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<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AR71</accession>
    <name>A0A9W9AR71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL39</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L39</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_313379</name>
        <name evidence="7" type="ORF">C8R41DRAFT_813842</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000008">
        <property type="protein sequence ID" value="KAJ4488748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AR71"/>
    <dbReference type="OrthoDB" id="6332053at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1620.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein-like L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_eL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_eL39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_eL39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_eL39_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970">
        <property type="entry name" value="RIBOSOMAL PROTEIN L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4488748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="51" mass="6366" checksum="656E0F761C2494E3" modified="2023-11-08" version="1">MPSQKTFRTKRILAKASRQNRPIPQWFRLKTDTKIQYNAKRRHWRRTKLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWK7</accession>
    <name>A0ABQ8UWK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_937316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000149">
        <property type="protein sequence ID" value="KAJ4463947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045868448" evidence="1">
        <location>
            <begin position="25"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="22158" checksum="E5D6378C6BD9EF14" modified="2025-10-08" version="1">MHSIISFLGFSLLTFTAVVLPVMSCHLGAIASPLVVHETSPAETTASLQLMVRADSYDSSQTSTQHNNTVGALERFEAGFIILGQRGRKKVRYYKYGAVLGRHAFVKEVNKPVTYKELNDREYATVRAAGMHEAMTLRMVNDETANMFRASSEHSCEWVVETLDTMKKHTDLLEGIDEKWRGLSDIEKEYIRNQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX74</accession>
    <name>A0ABQ8UX74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_937267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4464073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="458" mass="51054" checksum="491917A15E7D4A20" modified="2025-10-08" version="1" fragment="single">VGCGLGGLAAAYALGRAGHSIIVVESSPSIGEVGAGIQVCPNLSRILAKWGLVHKLKSIAERDKPTWFTFHRYDTGEVLGMSRLEGKLDRDHGAPWYVVHRADLYDMLFAKASPYMDLRMESKVVSVHFEQPFGPCAILQTGEVIFADLIVGADGINSVVRNYVTGQTEIPLSVPTGDLAYRVVLPTRTFVDDPQLRHLVDEPRIRCWIGPGRHVVGYCIRDRKEYNMVLVKPGDGHSYSWTAEGNLEEIRDGFHEWDPCVQKLLSRAESVLESKLLICRPLKTWIHSSGRAVLLGDSCHPMLPYRAQGSAMAIEDAVVLGNLFSRISDNSQIPDLLKAYEGLRHARASATQAASARNRSVYHLPDGLEQEKRDAAMKLAMEEELLNYEWSKDGDPPSVFGNRNRDNPNAWSDKNKNAEQFDYDPDTAVDEWWASESNGFQMDQSLESVEVDSKFPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXF0</accession>
    <name>A0ABQ8UXF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_740583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000162">
        <property type="protein sequence ID" value="KAJ4463466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="102" mass="12369" checksum="E1F6C8406903A75D" modified="2025-10-08" version="1" fragment="single">MEQLAERRMQREEEAVGDLEDDSEDEEDEEDEDGGEDEEEEEDEEEEDDDDEEEEVMTEEQKMEEGKRMFSIFAARMFEQRVFTAYREKVAQELRLQFLREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXK5</accession>
    <name>A0ABQ8UXK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_927636</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000191">
        <property type="protein sequence ID" value="KAJ4463236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="101" mass="11562" checksum="73923F4230881EB5" modified="2025-10-08" version="1">MTRSVVLVASWDLAPATHLRATWRWLTFTIYQIHRISQSNHLLVNEKALLLKITTDSSASTLVFSRLINSNEILRIQRMEMLLSFIPYGAAELQTVSVFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY19</accession>
    <name>A0ABQ8UY19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_98006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="680" mass="73328" checksum="9D4D8FDCD2F20A9A" modified="2025-10-08" version="1">MFGLLSSQFTGAELSKDVAPVASTEDAASSLRAAALLTLKSSKRRKVNTNQAQSSTFPIRPAGVDNSVQLDYGQDDAETDIASSPPEKPSLNQQPPPSIKIPEVDMEDGQVREEGEISDSEEAPKVIAAASVQSKTTTPSPTSKRPSPPKPSNNRHVLSSTFALKVETSSSSLLDRMSAVPPGPSSKSPQRVEVTNGEHTYFIDVDHVRPGLEMNQEQYDTAKDIVLDLLGWGVAPEYLLDCGLSREIVFYVFSELNLRLPQNLNTDGIIPYTPSTLEALLRVPTRVSSPLGSDFDTPRPLGHPSLPPKPSFPGQDRSRDSMPKPAESSGDTADVTVLLDMERQRRQELLARKAVQASRITRSMGSLSPTSKPMDVDDKDVEMTPSTSLAPSESVDDFLRSIEPVGSGKMDVDEVPGLVSTSTPVLVEREKSIDHMVESPSSQTPLPTDERLMSSVGASTSGEGSRRSSSSEDISGTSNGLARRNGKRPVAADFVDFDAAPRDRHGSGIKRSTGSFASISTMRRCVIDLSDSESEADGEDVQIKHAAVPPGTTNSRFSTPPASSAAAATPDFRTMSPAALAVKELEIQKMRQMIAEREQGRRMKLKKLEAMSNPDGIPVKQEEDLLSSLAIPVTQFPFMESSVTANTISSSAEIGSLISSPLILLLTHNRPCFFSLPRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY44</accession>
    <name>A0ABQ8UY44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_906748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1037" mass="113758" checksum="4EDE4970EBE723C9" modified="2025-10-08" version="1">MNTLRASRWVHPADIQKVNTVQTVNGRRMEAAQRNLHMQSGATISPFYHKGAAAKRSARHSYPQNQGFQGYGGGSVQSNAKAKSQDGFKFIVYFLPEMAPIIREFTTSPGTQYHPPVDVAYNDNQILRLFQRLAEYNLAVEVTITDNMSAKAIIDRIVTSLNVRLSELGITIPTPDPAIPQEKRSFYILWGNMRQGKRHYVPNRPGLLNDDWWTFKETQSLANKAPKTLGCATPALIAAPVAGPITWRGHVCCGPKLNYGFITERVDDDTGLHYTDCLQECRNSPKIPTIPLHFHFPPDAPIAFGAAALSPDHSLFDGISTITTSSSSSPLNAGRPFEELALSDDDDDDIQQGIVLPMKRRRDHATNSDEEHEDMAAAIKASMSTIQAEERRRLTGNSTEAGPSGIQATLPPVPNRSTYPSSSSNQYAADYICHSELLDATDMSHKVDIELANTASDLFRLLDQYLLVSGLQRSQRVVITATNCTTEAVADGLITSLINRAGYSLPEPMLMSITLPVQDIELLFPIEVFNLGHGYGSSLPKTLLGCAMERMMSHTEIWRPCGDQHLTLELNRLLSAQAQATLKAFGNLVAMSLVHLHVIPRRLSPSLMLALIHESVDSLDDQEFISFLPALQRILLHWHSNPSREIPNNDVTSEVALAFNCTVADFNTPVIALYGVGLPVSGQCFEDHWAVKAFRSGLNISLASGVNLLDLFGPETKSILKELDQQFPDSGDDLRPYISYDASACPEKQSRVDEFMMKFFRWANRPGHVTHASIAEALPTGEAELYSNDYSFRPRRFLQCATGSEILSNSTKITFIFTSNKLPVYETVYRRELPPDARSSTLLSIIIVSKADGGSKGTQLYVLLPPGTWVQKVVSRMNEAIVSKADEGLEVLSELYVLLPPGTWVQKVVSRVNKAIVSKADGGSGSTQLSVLLPPGTWVQKVVSRVNEAIVTKADGGSGSTQLYVLLPPGTCWVQKVVSRVNKAIISKADGGSESTQLSVLLPPGTWVQKVVSRVNEAIVTKADGGSGSTQWVIQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY62</accession>
    <name>A0ABQ8UY62_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SNTX MACPF/CDC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_109428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052090">
        <property type="entry name" value="Cytolytic_pore-forming_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056072">
        <property type="entry name" value="SNTX_MACPF/CDC-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31594">
        <property type="entry name" value="AIG1-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31594:SF14">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24674">
        <property type="entry name" value="MACPF_SNTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SNTX MACPF/CDC-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="688" mass="75909" checksum="32CAB79B63BBB128" modified="2025-10-08" version="1">MGFQSQEMDLPALGRPAFLGQLYDATSERLMNTQLFSPEVASKVQIVPNPSNSVKFKDISTISERSHALDINAELSLSILGGLIDLKGSGQYLDTSKSNVSSREVSMICTTRRNLKRLDLKGSDTITLDAYERAVKRHATHVVTGIIYGGTLVTNVVEKASFSESRTKIHGEFTASLMKKMAAAFSAEGKAAVDSDKTSKDVLQSHDFDFYGDYVASDRPNAMTIGDLFELAKTWPDLVGDGVPCQITVTPLDQLVDESVEAKILHELESDELIAILAAYDDIFRLAGRRTRIQVALEPGSGNLGACCPTFMDICKKRKIITDGILGRSRRALSKFLIAFRHGGIEEAGKTTTEFVDAAKVGLTERLKECEQDESVLGLLQNIHELAISHGVPLETLNGLRRLMTQADKKMLGVVLVPPSPNLDGAINTYDVLVSNIKRWRVDEDKKDTSVDGKAKETLFVSLYCDPALAPDILNLDGRKGVLKKALDGFEKSRGSRFVHYGVLPNGISTIQKQIDWSLLNDEGWAFIHNDQESFDYIGQVSGGKRHGRGTVTYANGSTYCGDWWYDQRHGEGKLVEKSQEITGVFINDQYCADGIIADLTILAHYAPIGAAKIPLRKRNAGTAHVSTIGTMLGWMETEEYKLVVEAKGDQKLEMIVVGKLIRHDQDEMFNKSWPLEEGVEIKVERRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZZ5</accession>
    <name>A0ABQ8UZZ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="556" mass="62121" checksum="EF696B0647068832" modified="2025-10-08" version="1">MVNQVSQLKAAAQLLAIFYGLTILAWRLLRRYLFNRSSGIPEIENIGKTRLPEQKLDGTALICGGSIAGLLAARICSEFFEHVIIVEPEEWLTSEDGMRRFAWKQEHKRTRVMQYQSLHGSQALLYAGLRKLFPDLAEQCRYSGIAIYPADRKMSFAGTLIPAPVESYHGHLPETLVASRAGLETLLRRLVLGRGNYRNIVQIAGTVIGLSPHSDDLSRIGRVKIRRTDSRIEELDANLVIDCTGVTRAGVKWLSQAGYGSTDVNIDGKLHLKDAKISFDQKLQYSSLICDVTPDTLKKLPIPNDQTIETMFFGLLEDDPNNGRRFFVMTKADGDRIVIFVGQSSDDPVKYESLNAMRSLIPDLKTHKNPIPGWVIETIDIIEASQPEVHSSQLRIPPTAYIRYHQTVNLPSNFVALGDSVSSVDPLYGQGCTKALLGAVALHKVLSAKTQVDTKELPADFSEQFFKEHSKKTDNFWQLTHLLDYGIPSTTPLPGEDLKVGRLLRWYLRRVQILATKDAQAGRAYWDGVMGFGTSVDIFHPFLVLKTLFNTLIGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V032</accession>
    <name>A0ABQ8V032_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_861957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000186">
        <property type="protein sequence ID" value="KAJ4463253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047362383" evidence="1">
        <location>
            <begin position="23"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12355" checksum="50D0325AC27031DC" modified="2025-10-08" version="1">MRLAHSLRLTIAVLSFACAAFAAPVMKLETGKIIGDGPTNVQDNINSSISQRGIFHICSVTFDQARHVTEVATVDSKANDLAQQWVVRLLQEEIPRAAVCWELSLFDSVSRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V061</accession>
    <name>A0ABQ8V061_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_50674</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4467618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="25197" checksum="4A750E8085B5652D" modified="2025-10-08" version="1">MMALGLLTVKESPRYLASVGHNEEAINNLAYLRRSPADSESVVLEMAEIEATIQEECLARVSLGWREAFFGKGNAIHFLIAFMIFLLQQWSGQNSVTYYAPQIFASIGYTGTKNSLLASGVLGVVKVVTVSTFVAFGVERFGWKRFLFISSMGMGILFFIIGALLITHPPPAASANDAPSSPSRASQAMAAMLYLEGVCYVIRWGPLPWIYVSEIFPTRTRHYGLALGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0N4</accession>
    <name>A0ABQ8V0N4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_779981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019180">
        <property type="entry name" value="Oxidoreductase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039251">
        <property type="entry name" value="OXLD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193:SF3">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09791">
        <property type="entry name" value="Oxidored-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase-like" evidence="2">
        <location>
            <begin position="92"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="205" mass="22738" checksum="C0588F4A96D34813" modified="2025-10-08" version="1">MLTNACLTLPLAFRCSIITTTRRYSSLSALPSPRARQHSQRGGQNLSERYIRLEKSLRGKEALEAEYENLHRSTLTGPSAGKNAVAGDTDGTFRGLVIPEKPREPQSDECCMSGCAVCVYDLYEDSLAAYGEAVAKVTATLNVMGVPESDWPWKLRSRSEAMGMERKKDVTLSVFEQMEREIQRRKQQENLVTDSVHSSLSMGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Q4</accession>
    <name>A0ABQ8V0Q4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_784533</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000182">
        <property type="protein sequence ID" value="KAJ4463287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021538">
        <property type="entry name" value="Syntaxin-5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11416">
        <property type="entry name" value="Syntaxin-5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="240"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4463287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="35735" checksum="338247DD9C36B2E2" modified="2025-10-08" version="1">MPVQDRTNEFLACVDSIISRTSIPSRRDTKQKLLQNGKSVTKSEFSRMASGIGKDISSTNIKLGKLSQLAKRKTLFDDRPVEISELTFIIKQDLASLNKQIATLQAYVKQKKAQGAKLEDGNQINEHHKNVVTLLQSKLADTSVAFQEVLEVRTQNMKESKDRTEQFMYTASIAASQPPSNSVLFNTRGDPMGDGSPSRYDSKRPQNGDMLALNLEAAEEGSGSQNGGAFMQMQMIEQQDSYIQSRSTAIESIESTIAELGQIFMQLANMVAEQGETVQRIDADSHDIAANVSGAQRELLKYYASISSNRWLMLKIFGCSSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0R4</accession>
    <name>A0ABQ8V0R4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin MVP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_912321</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07597">
        <property type="entry name" value="BAR_SNX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045734">
        <property type="entry name" value="Snx8_BAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554:SF1">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19566">
        <property type="entry name" value="Snx8_BAR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="11">
        <location>
            <begin position="237"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4466967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="682" mass="75522" checksum="C741AEB4E2C8B3BD" modified="2025-10-08" version="1">MFNSPRPAQRYGGNTSAGLGRSFVDEDPLASSAYDGLDPWSAAPSPSSTPAPPAYSVFSSVIADATVPSVYTRAFAAVDPGNIGETSVNSLSRVLATASLPASTIDKIVNIVSSKPRVSKLEFFVALALVALAQSGKEVSIEQVAALSSQNELPEPTLDLNSLQPSASTFSAPVPSYTQDTVIRSPAPHYTPDDPWDTTTRYISAPSNMSGFGNSGFGPGAPSTVTGTGLSKDWWKNQKSVSVTIQGQQGFILNRYTVYQVSTERGSSVIRRYSEFVFLWDCLYRRYPFRLFPALPPKRIGPDEYFLEQRRKGLARCLNYVINHPVIKDDGVLSVFLSETSLEEWRKHTSISLDEESASKRIDRAEEMSIPSDLEDKITTIRRRVSPLIEQWQRICILAERIIKRREAAAVRMSSQFRRPLIPAHLLPLFSPSHQRSFSDSASITSSAAFSASGMSATSTLSQSTTLNHSMTGSLPRVDFLGLQGDLSRLTNTLRAVIEVGDPCWRGDECELSSGVRTGLEQVASHFGRHSELSESRTRVLLDTTLEAVKSQRDLYIAVRDLFIRHDRLSLDQVERLKKRVETTSLKLDGIKAAQKDGWQDEADKFVAAIEKDQATIAAQLSRRVFIRACLWHELRVILHNRENTLLTVMTQSFAHEEQEYAEAMLNNWSSLTEAVEGMPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Y5</accession>
    <name>A0ABQ8V0Y5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_738489</name>
        <name evidence="2" type="ORF">C8R41DRAFT_745384</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000146">
        <property type="protein sequence ID" value="KAJ4464158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4485104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="67" mass="7813" checksum="421EBCA244BE2054" modified="2025-10-08" version="1" fragment="single">FWDDKLTDEEMDLICGSYEVATGSEGQQQTAIKSWWPRSGSWRSCGLNCGYWSSDAEDWFRNRLDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V163</accession>
    <name>A0ABQ8V163_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_778430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09998">
        <property type="entry name" value="HDAC_Hos3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053244">
        <property type="entry name" value="HDAC_HD_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="113"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="595" mass="65008" checksum="3211A9EDE91C5AF5" modified="2025-10-08" version="1">MANASIFIQDACYQHRYIRSRDTSLIVERPERLIAAKIGLAAAVIRMQEVVGKSAGDPNDLVAALDKLTLGSRSSDITAPINVVHSSATLDILDHPAVKFTHGFPDPNTAKDSNEYLRNLKKWSEDSIEKISKGDSEIPQGLAQGDLYLCPESLNAIQGALGTVCECIDTVVDSNPSSSKRAFVAIRPPGHHCGEDTPSGFCFVNNVIVGAAHAHLKHGIHRVVIFDIDLHHGNGTQSLAWAINEETQRQKLEVEARIEAGNSPPATIPGLQIYYSSIHDILSYPCEDGTPSMVQAASVSISGAHGQWIENVHLKDHAKEGDFWGLYEEHYKKIIHKAEEFVLSTATKNNEDVLVFISCGFDASEHEYASMSRHGRKVPTNFYAQFTRDARVFAEKHAKGRIVSVLEGGYSDRALISGTFAHFCALGLSEEHTWNETWWNKDNLDALQNATKTKKPRGHVSPPLSAPKTDPEPEPWLKQAVSIFQHLEPIPFKTPRKGKAILVEPSSRTLRQRKVGSSSPASAKSKPEKSQGKKTEPVVITESTRSDGQAEDSDSSTESFSTLSSMSDSDAGLPISAPSKKLPRVILKLGPPPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1W0</accession>
    <name>A0ABQ8V1W0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_854909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046222809" evidence="1">
        <location>
            <begin position="19"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="67" mass="7528" checksum="A085D888D445C713" modified="2025-10-08" version="1" fragment="single">MNLRILLLSICNALYTLAKWYFRIGCSCRKCGNTDIPAQTGKPCSISKYPFVSPSPFDPEGTIEHEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V224</accession>
    <name>A0ABQ8V224_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_925370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="3">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4468559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="74" mass="7920" checksum="3FB1168281ECE266" modified="2025-10-08" version="1">MSQTKYTTLINNYFQTPGRSSDSLSFEESSVGAADKVVWTVICKVDGETKGRGESSTKAEAKNQASKNALEALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V273</accession>
    <name>A0ABQ8V273_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_870834</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="77"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="633"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="669"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="712"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="755"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="798"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="841"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="884"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="931"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="974"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1017"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1061"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1104"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1147"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1190"/>
            <end position="1223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4470315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1278" mass="140424" checksum="19D4A04F3F95D894" modified="2025-10-08" version="1">MFSQAHNFHISGGQFNNVQGNQYQYNMGSGLDKLNPSYQAFFDTDMGVELSRSFCTRGTRTEVLDRILAWVTESNLNDNHSGGYWMSGMAGTGKTTVTMSLCKELKETHGILAATFFCSRQIPECQDYKLVIPTLVYQLAMFFPDFSALVQNVLDGDVHVMHKKSSEQIQKLLIEPWGMQKDLHSPMRMVVVVIDALDECNGIESVLGPLVSAIQNKKLTGLKFFFTSRPEQVIEEGMITKITSTQEILQVDEFVLHQVEYNLVQRDIHTYITDELHDLALSQEQLKTLTNLSGKLFIYAATVIKSIKGGSGIRRSRTRQKERVKSFLRQENNTPEDLSKLYAGILESAIAKEEPSPSEVLENWKIIHTIISVGEPLTCYAITQLLGMNLEDDDNDNDIVENLIQRLQAVFYISKSTNLVFTFHASFPDFIMQYDQVVYNASIQHLDLTFSCFTIMEKLRFNICNLHSSLIADSEVKDLNERVAENIGETLKYCCQFWNYHFLKCSQSSYEEVLGKLELFLKQKGIYWIEAMSVMKLLPRCGEIITLLLKEIVTSQQMNTLKALVEHLQSLLIQFASSEVKDMTPHLYLSIIPFWQNNLGCIPYIHKSVKIEHQVGNWHAQDTVTINTSPFIVHSLDFAPDGTKLVLGCSDSTVRIWDASTGVQIGDSLQGHTRTVNSVAFSSDGTRIVSGSDDETVRVWDAGTGVQICEPFKGHGRYINAVAISPNGTKIVSGSDDNAIQICDAQSGTQIGNPLQGHDLKVSSVAFSPDGGKIVSGSLDRTIRIWDTNSGVQVGNPLLGHSQHVTSVAFSPDGKRIVSASHDKTVRIWDAITGFQIGSALEGHESYIHTATISPDGTKVVSGSSDSTIRIWDISTGLQIGDPLNFHDKGVAAVVFSPDQTNIVSSSYDETVRICNISGGIQFLTGSTPGLQGHNDAVNSVAFSPDGTTIVSGSHDKTVRIWDAATCVQVVNPLKGHENFVTTVSFSPDGGRIVSGSWDKTVRIWDVRTGTEIGAPLVGHETHIESVAFSPDGTKVVSASWDIVKIWDSKTGHQLVGDILKGHNNSRVNSVSFSPDGTLIACACKDKTVKIWNASTGVKVTAPLPNYNNGVNSVAFSPDGKQIASGSDDKTVRIWDASTCVQLGNSLQGHDYIVTSVAFSPDGRRIVSGSLDRTIRIWDANTGAQVGAPLQGHEAGVKAVAFLSDGTKVVSASWDSTIRVWDIFSDIDKGDTLKYDYMSIVSIAFSQISPANGSHIVYDYSMTEVGNTFLNQTAHISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V274</accession>
    <name>A0ABQ8V274_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cullin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_858337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000125">
        <property type="protein sequence ID" value="KAJ4465585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1030.10">
        <property type="entry name" value="Ring Box Chain A, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="6">
        <location>
            <begin position="413"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4465585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="762" mass="88268" checksum="A767707D6A5AAD99" modified="2025-10-08" version="1">MASSSSSSPFTKPPARAADLDETWAFLSQGVDHIMNKLDTGMNFDSYTNLYTTVYNYCTSTKMQGRQDSNRSGANLVGADLYLKLQEYFVDHFKPMKEKTAGLQDEELLRYYATEWDRYTTGANFLNRLFIYLNRYWVKRERDEGKKTVYQVYTLALAQWKQHFFVPIQQDNIKLAGALLRLIERQRNGEVIDQGLVKKVVLSFVSLGLDNNDLNKECLDVYKEHFEIPFIEATEKYYKMESETFLASNTVSEYLKKAEDRLREEEDRIERYLHTKTRKELISKCEHVLIREHSELMWESFQKLLDFDQDEDLQRMYALLSRIPEGLEPLRKRFEGHVKQAGLSSISKLVGEGGNADSIDPKVYVDALLEVHKKNSETVARSFKSEAGFAASLDKACREFVNRNAATGSSSTKSPELIAKHADMLLRKNNKMAEEEDLEGALNRVMVLFKYLEDKDVFQTFYTTKLSKRLIHSVSASDESEASMISKLKEACGFEYTNKLQRMFTDMSLSKDLTDSFKERMTQNHDDMDITFSIMVLGTNFWPLNPPPHEFVIPAEILTTYDRFQKYYQQKHSGRKLTWLWNYSKNELRTNYLNQKYILMTSSYQMAVLVLYNKNDTMSLEEIFVATSIGKDILTQVLALLVKAKILINEEADQYDLNPGFKSKKIRVNLNLPIKAEVKQETNEVLKAVDEDRKYAVQATIVRIMKARKTMKNQALIQEVISQISHRFAPKIPDIKKAIETLLEKEYIERVEGSKDTFAYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2V9</accession>
    <name>A0ABQ8V2V9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanine nucleotide exchange factor Vps9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_857809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000122">
        <property type="protein sequence ID" value="KAJ4465744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041545">
        <property type="entry name" value="DUF5601"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18151">
        <property type="entry name" value="DUF5601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="401"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="861"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4465744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="906" mass="98484" checksum="DE9A6A7C8A77D31E" modified="2025-10-08" version="1">MEPSTPSGPTTNTTNQVNTTTVNEVQESLQGLSVAEAADQGATVKDGEVHKNLTPTISPNPWSDSERHFTSTARERELVLVPTDVEDEESEPGADDEAEARHILHTPDPSTFDRYVTGGFASDSQASAPLVAPPPATEILQEFDPLADQEEEHAKKAWEESEGHPAPPLPRDRISSPPPPVPLKDLPSPSPIPILSAQSSGGFQSSLVALARSFSIPSLTRSPKSKGRPLSMDVAKPVPSPDTISSFATQQAKQPELNERKPESPDRQEEEDFEGSDTGSEDSGPGDPPFDFQKFLDQMKMRSADPVSKYLKSFLSNFSKRTFTVSDQIKIINDFLNFISNHMRQCEPWKTASDAEFDNAMEGMEKLVMNQLYQYTFTPAVAKDLNPITGLPRRPISVDDLERDRILSERIALFGWVEEKHLDIPVEEGTAGFLMFAEQELLKIGHYKAPRDKLICILNCCKVIFGLIRHLQKEEGADAFVPILIFVVLKANPDHLLSNVEFINRFRNPDKLRSEAGYYLSSLMGAVQFIESMDHTSLSNITQEEFEQNVEAAIQELPTNPDGTPRVLSRGSSSSSSSASSSLSSISTPTQRSSPHLGAESAQPLSLPLSQNVYSQAPMAQQLSEDARRLLQKTGDAVSKPLNAISRIFNEALDLAEENFGSPERYASASTSRAGTPSGSAPSFPVPNWPHQLVPGMASQSLPDSRSSSPASFIAQGVYQTPAPSADGGPPVQTPYKPRVRRVPSPGGYLNQAQAPLYGQSVLSPGYSPGYSPGFSPEDTPSRPRPSGQGPQTHYPLAMGPSQQVQPPARVQSLHPYYDQPGSPNLNLGSPLNYSRASTPGNGDLDIAGMQAEIDTAHSQATEASRNTLFQIFPGVDREVIEWVLEANEGDLGKSIEQLLEMSEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V365</accession>
    <name>A0ABQ8V365_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_851846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="419" mass="46500" checksum="E10D310BB8DB7C04" modified="2025-10-08" version="1">MLQLSGALRRRDQPSRLTANPSPPSSLLAVPSSRRSLANQSAESFSSAGGISTAPSPSRLQPPPPRGSRSRKKSGPSVVRKPKDPDSVPRTIAYPASSELQQRPSAGKETNSNQILRVEANTVRIELMLRRMIEELRSSLLSAAAPHHQELLQASAAERTQMEARLMGSLQDDIRGITRSELKLLESNLQQKLTSLLPMEAINRLLSSLENTFTHLYDPVPPIQGLPTSTPPPERPSVQYEPHQSSNLPSTPPKPLPPSHQRHTPRISSTTQSPSLLTRLQDGPSSSQPETVSFDSKRSMIKAGKRRALEHEEDSRDSKRRPHNSRTAHSVSVFLPSEWDPLPFTIDRIFTMYYRWSSDFDAAVHVTLPRVGFITRIGGDRLKLSFSPEGLEEFLRAWNAYHKVVPGLADIVVCRDNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3F0</accession>
    <name>A0ABQ8V3F0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial Rho GTPase</fullName>
            <ecNumber evidence="15">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_776329</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Mitochondrion outer membrane</location>
            <topology evidence="2 15">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the mitochondrial Rho GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01893">
        <property type="entry name" value="Miro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01892">
        <property type="entry name" value="Miro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013566">
        <property type="entry name" value="EF_hand_assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013567">
        <property type="entry name" value="EF_hand_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021181">
        <property type="entry name" value="Miro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052266">
        <property type="entry name" value="Miro-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020860">
        <property type="entry name" value="MIRO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08355">
        <property type="entry name" value="EF_assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08356">
        <property type="entry name" value="EF_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037488">
        <property type="entry name" value="Mt_Rho_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51423">
        <property type="entry name" value="MIRO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 15 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 15" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="18">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="17">
        <location>
            <begin position="186"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="17">
        <location>
            <begin position="306"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="18">
        <location>
            <begin position="415"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR037488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4472406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="645" mass="72187" checksum="CB3EA5F437EE3750" modified="2025-10-08" version="1">MRRDVRILLVGDEGVGKSTIVTSLIKEAFVQHVQHIVPEVTIPPEVTPENVTTYIVDSGAGPQDRAHLESEIRKAHVICVVYSIDNPNSFDRIPAYWLPHFRQLGVNVPVILVGNKIDLRGGEVTNEALEDEIIPIMNEFKEVETCVECSAKMPLNVSEVFYFAQKAVLHPTAPLYDSRDHMLKAACVRALKRIFKLCDLNKDGILDAHELNEFQRKCFDAPLQLQELEGIREMVTQHADGGVREGGLTEAGFLYLHTIFIQRGRLETTWTVLRKFGYAEDLRLTEAFLSPKFDVPLDCSVELSPPGYQFFTDIFETFDKDQDGALNPSELEEVFGTSPGNPWASQRFPDTTLSDDTGSVTLQGWLAQWSMTTLLDHKTTLAYLAYLGYPDEPRTSALQVTRARKIDRRKGKVSRNVFLCYVCGAAGSGKTSLLRAFLKKPFSEIYEPTSKMMTAVNAVDIEGSEKYLVLQEFGSKYEAETLRNSKKTDLADVIVYVHDSSDTNSFSYISNLRQQYSLDHIPTLFVATKSDLDLAQQRHEVQPDVYCRRLGLQVPVSVSVKTNQTADVFHAICSIAMKPLSAIPGGAERALSSSARLRMYFTLTALLGGCTAGLFMLYRTLIRPGSALFPNWTTGWAGWLLSNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3T2</accession>
    <name>A0ABQ8V3T2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_970308</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF97">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="88"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4470530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="545" mass="60450" checksum="B9E62F6526CB1C0E" modified="2025-10-08" version="1">MPTSTFQVSQEAPDSPALDVEKTEVEQVENVLPRTPYQSEEPGPASILNWLQKKNPSPQFLADVAKMNETELDAGKVKHVERKIDLLIMPALAICYMFYYVDKTTLSYAAIFNIKEGLHLGSSDYSWLSSLFYFGWLGWALPTNLLMQKFPLNKYLAFNIFLWGILLMAQAASRNFTELAILRVLSGAAEATADPAFVLITGTWYTRTQQPSRIGYWYLANGFGIALGGLFGYGIGHIKGSLPSWKYEFLIIGALCSVWAIVMAIFIPDSPYFSHWFTPEERLIIVSRKRGDHNSTDTREWKPAQVLEAFIDPKTYLFFLFGFTANVPNGATSNFGTLIVQGFGFDTFQTTLMQIPYGMVIVAFILAAIFINSKLPSGYRTLLMALTNVPTVVGFAMVAWCKGTGPRLAGFWMTGASNATFVLGLSLLSGNVGGQSKKAIASAAIFLGVAIGNIVGPFLFKTSEAPTYYTGVVGCLVSRALEIVVILILRVVFIMSNRRRDRAVAEGRIRYSEQFTELEDITDWKNPAFRYVTVNLITDSCVTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3W9</accession>
    <name>A0ABQ8V3W9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046340313" evidence="1">
        <location>
            <begin position="24"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="18190" checksum="9D5ECC0E57C3EAE4" modified="2025-10-08" version="1">MFKQVRSAILLSALAVAVPVVRAQSTVALSWNSTSPYGQSNGDFTLVQGTYGYAMAFTADSSSSPTATYSEEFGSLVQHCPEIGYIAALIPQSGVIPETYILEWVDPTITLPEGSSTNSLVPASGGFVSTLGTGIFKGIEVDNTGVFAWVNETSAQDGGVQYWIVTTPDSTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4E1</accession>
    <name>A0ABQ8V4E1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_621197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="148"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="205" mass="22291" checksum="694D6B07586D88FF" modified="2025-10-08" version="1">MAFSNLSHHEKDAFFSLLDEYFQSRPELTAKLQGASGNNDEGSGVNASQVAGRVAAAASAFNNAPPPSRRAPPRNIEPPAGLVSKQRLGDVDTSSKKSMLVSGLSRKQPVVHNTPIAPSAFGSKKNNFAPPPPHRAPEPEPEPEQEEERGEWAEALYDYVSQDPADLQIRANQQILVTERTSDDWWTGEVDGKSGLFPATYVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4J4</accession>
    <name>A0ABQ8V4J4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_563330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051589">
        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964:SF5">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="10"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="121"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4473941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="251" mass="27188" checksum="F6743A54AEC77404" modified="2025-10-08" version="1">MISRQTIPSGWAFNSCFIDNTSAGRLLTINSGLPPDTMTVPECIEYCSSNNWAYAGVEYASECYCDQVLHEVGSQVTAASDCNMPCTGDPSQTCGGPNLIDVYWDGDSTIPSSPPTLYKSYWSYSGCFVDDTTQRTLAQQVYPDSGIVTPLSCADTCAFYGYTVMGTEFGGECWCGNTTNSASQLPDTSCTMSCTANRDYLCGDAARLSVYHHNTPPAGNLHRRMPRLRPPTLGGHLQFHRPRDPQGGSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5F8</accession>
    <name>A0ABQ8V5F8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_557803</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043323">
        <property type="entry name" value="PIN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45995">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13616">
        <property type="entry name" value="Rotamase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="41"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4474182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="136" mass="14419" checksum="C58C07665F4DA429" modified="2025-10-08" version="1">MANKKSSTTSNKKNDETKGKSGNGSAGDEKSSKGKGSLKAATAVNVRHILCEKHSKVTEALQKIQEGQSFNKVAGEYSEDKAKAGGSLGWMVRGSMVGAFQDAAFALTPSTVDKPIISPLVKTSFGYHIIMVEGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5R7</accession>
    <name>A0ABQ8V5R7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_550905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="34"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="53360" checksum="6B2F45006F5A97CE" modified="2025-10-08" version="1">MKVEVATEERASLETSGSWFMEEKRLIRKLDRRILPIACLLYLFAYLDRSNLGNARVLTGTNDGKPPLPTDALGGDPTGILFDWVNSAFFFSYILCQVPATILSKLVAPRIWLALAAIGWGTCSTLMSTGFDFGGLMTTRVFLGIFEAGFGPAIPLYFSLFYTKEEMGLRMAYWFGFAAVAGAFGGIVAFGIQNAVLPFSNWRLLFIVEGLPAICLGIITFFVLPDRPESTHYLDEREREIAIARMNRGTSGDVGAVVNKSHISMAFRDWRIYTGGVIYFALNCSLASTSAFLPTILKTLGFSSARVQLMTVPPYAVAAFVIVLGSWISDRLQSRGIPVAFASLVGGVGYLILLFVPTNLHARYFATFCITSGTYTSIGIIIAWFAHNLGSETKKATGIPMFMAIGQCGSILGSHLFPTTEGPRYIKGFAVCCGLEIFGALCALVMTISYRLDNARRNKLHGVPKEDARVDVAEMADKVCPLPFTNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5W0</accession>
    <name>A0ABQ8V5W0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Glycosyltransferase family 24 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_552763</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06432">
        <property type="entry name" value="GT8_HUGT1_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040497">
        <property type="entry name" value="Glyco_transf_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009448">
        <property type="entry name" value="UDP-g_GGtrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040693">
        <property type="entry name" value="UGGT_TRXL_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040694">
        <property type="entry name" value="UGGT_TRXL_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040692">
        <property type="entry name" value="UGGT_TRXL_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040525">
        <property type="entry name" value="UGGT_TRXL_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226">
        <property type="entry name" value="UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226:SF0">
        <property type="entry name" value="UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18404">
        <property type="entry name" value="Glyco_transf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18400">
        <property type="entry name" value="Thioredoxin_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18401">
        <property type="entry name" value="Thioredoxin_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18402">
        <property type="entry name" value="Thioredoxin_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18403">
        <property type="entry name" value="Thioredoxin_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06427">
        <property type="entry name" value="UDP-g_GGTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047245260" evidence="10">
        <location>
            <begin position="18"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="11">
        <location>
            <begin position="31"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="12">
        <location>
            <begin position="300"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="13">
        <location>
            <begin position="433"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose:glycoprotein glucosyltransferase thioredoxin-like" evidence="14">
        <location>
            <begin position="708"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="domain" description="Glucosyltransferase 24 catalytic" evidence="15">
        <location>
            <begin position="1261"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1551"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1573"/>
            <end position="1584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4474795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1584" mass="178101" checksum="7AD6195D4A38A628" modified="2025-10-08" version="1">MLSLLPFVLCLSRYAAASPPVKVSLRTSWPAPPFLVEIIETVALENSKVFFLFLDRVTDPDVVIITPNEAPEAIYSSSLEVAKNMGLFSESGALAFVEMSLALHAATPKIEAFYHHYTETVDQSARRKECGSWVDWYGSVVCDVESLAQLAGLDTIDSMENYSPKILPFDHIYPPPESRLETPPRTAILYASLTSPNFRELHTYLMRLTSHAEHRIEYILRHVPPENLDTSKRSYLSGYSVALDLKKMDYLALDDRHLGTQRDDPSLSDDQEVEAPVVDPIFSLLDGYPENSTAPDANTPPTEDELHTIGFQASQLIMDSSNPLLTLMHLSQNFPKYVTTLARRVSVNEGLAQEVHENQLRVQGGANAMWINGVSVAEKDLNAFGLSRLLKKERGIMMQLTGLDLERGEAIELLTHPILSAAQDSKDVLDGLVDASDRAEGGDVIIWWNDLEKDKRYNQWGASITGLLRPLYPGQFHMLKLNLFNVVLVLDLSRPANLVFVAGTMHSIIERGFPFHFGVVPIVETEDGARMARLVYFLLNNFGRKITMNLLKRVAHPFTMPGAQGSLQWSNIRHEYDGLMVAEANAGATIDQTSVDFESIVSGTNSISKSLDGVQAYTNRLSATLSVFPSGHGFINGKHFAFDESFLRNMQTEISRQLMHLQEEIYEGHLTEEDNGRISSYFFDLPTTARRRNKYIVPSKDNLDIISLPELQKDSSSIFAPSSFVYPTEAEVIPMTLFVLADLNAKDGLDFVKEALLSMEKNSTARLGFVHNPVTEGFSQEISTSSIFAHLVDSKQLSKTSPEELLQALNSGQYASEVDESNTQVPFSTVRALKNALKLDHLDDHKPNEQSGFLDACQWFVRSIGVEPGQNGIVINGRIVDAIIPNEFLAADFQALQEYELLKRIQPVLSALEDIRPVFKSLDRATIAHTVSMTSSIISAIQVPDPSEVGLFDAPRRPRNRNYQTLETKHTLFEVGDNSTALYQVAVIVDPLSETAQKWSSLLQWISHIPDTYLEIRLNPTQYGEVPLKRFFRYNLRTSLSFDETGQEVSSQTVFENLPLEPIYTLAMDVPPSWLVRPREAMYDLDNIQLGSLAPEDSSVDTIFDLDYIVVEGHARDTTTQSPPRGVQIQLVSGSTPIDDTQVVANLGYFQFKTKPGVFKLEIREGRGRDIFVTESVGNEGWNSPSVDEVGNEITVTSFEGQTLYPRFSRLPGMEREDVLAEEEEEESSSVFESMFASVKSLFGTSEETGIVETADEQADINIFTVASGLLYERFVGIMILSVLRNTKSTVKFWFIENFLSPSFLEFIPHLAEAYDFKYELVTYKWPSWLRAQKEKQRIIWAYKILFLDVLFPMDLKKVIFVDADQIVRADLQELVDLDLHGAPYGYTPMGDDNEAMEGFRFWKTGYWADFLQGRPYHISALYVVDLVRFRQIAAGDILRGSYQQLSMDPNSLANLDQDLPNNLQREVPIFSLDEDWLWCETWCSKDRLHRAKTIDLCQNPLTKEPKLARARQIPEWEEYDSEIAKFARKLSEEGKIRSRIAAADANALARTASGAASLSPESDGLDDAEKEADEKKPELRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V695</accession>
    <name>A0ABQ8V695_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_897241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="293" mass="33263" checksum="23A1864B75C4515D" modified="2025-10-08" version="1">MDINVDGSSESSQQQKSHYILPSDSRETGRLNLQHRLIVKAFDGKLVSAPLTFKSGDRVLESGAGSGIWTLEFWKEYSQKNIHLDIECIDISRDQFPSQVPSSVHFSLRSILDVPLEWSDQFTFVHQRLLVAALPRPLWHKALHQIYRVLKPGGWLELVESHAKIRKFAVGPNSKNLALISDRMFESKDFVGDTEVYLPPVMREMGFVDVHCEGRDVPISNSRSVVDDDGLDRVQIWYDLWKGFKGSVLAGGGYGIVSSEEEYESLLLGCKDEWNNSTEAYTSYWTIIARKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6E8</accession>
    <name>A0ABQ8V6E8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_594869</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Self-assembles to form functional amyloid fibrils called rodlets. Self-assembly into fibrillar rodlets occurs spontaneously at hydrophobic:hydrophilic interfaces and the rodlets further associate laterally to form amphipathic monolayers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045009114" description="Hydrophobin" evidence="7">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00093546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4471920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="109" mass="10742" checksum="295709AAE3127797" modified="2025-10-08" version="1">MQFKLAFVSAALATLAVATPAPRDEPASSCSTGPVQCCDTVESATDPAVSTLLGLLGIVLQDLDVLVGLTCSPITVIGASGSSCSAQAVCCDDNSLGGLISIGCVPVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6G6</accession>
    <name>A0ABQ8V6G6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045475324" evidence="2">
        <location>
            <begin position="20"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="215" mass="23187" checksum="E5037B3B5ABB90BD" modified="2025-10-08" version="1">MRFSIFPLVFLALISAALAAPFNAASINDLRIRGPSAHAPGTPKSFETSAQHSCPPSKKLSDSLKTKLSQLKTKIATLKGEVKEVTSSPRWKEKVDQLKRLKEEFGDWPRSGKGPPPQHDTTTIIVIDDNNNCPDDSPRLLDQVGRVNTEISRLELPDQMDPEVVDKFQVLADGLGQIMSQIGDSAGQFAGQAADFAGQAAEVIGEILSALGDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6K3</accession>
    <name>A0ABQ8V6K3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="171" mass="19219" checksum="9DED2EF29C4EF1FB" modified="2025-10-08" version="1">MSSRLASLLTEKIPGGPISTSSTEVTVLPNNTMRAFCYLAEAQYQYLSGDLEIRPQEKAKFRSTSQSNSQSFKGSKRIRKSTEDCPTSVVRIQSDYLPATPHPISPHSASTPASAPTSLLCEDKDRLQVDIWSEDRKKTNREGTRICTKGWDEKSWRSYRVQFKPGVEDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7X4</accession>
    <name>A0ABQ8V7X4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_963429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045278483" evidence="5">
        <location>
            <begin position="20"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="113"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4477593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="424" mass="44275" checksum="F89CB149DD87492E" modified="2025-10-08" version="1">MFAKSALVAFVTLATLATATPMQPRQAGGPIFLPKRSSLTKSDGTFDYDKAVAQTVATKNKHRQNLINLQNNTGSLPQGFEIKALTSLPSSVEANLKKRQSEALSDEEDDEEWAGTISIGSPGQSFLVDFDTGSSDLWVPSSSCTSSTCSAKSTYDSSASSTSSKESGSFSIEYGDGSTVSGPVYEDTVTVAGIQVSKQKFSPVTTLSSSFASDPADGILGLAFPAISNLDADPFFVNANSQNAVDSNEFGFYLASSGSELYLGGANSDLYSGSIEYHDVDTSTGFWQISGASIASDGTTAVSDFATIIDSGTTIMYGPPSAVKEFYAQVSGSKLYDSANGFYSFPCESAPEVSFSWGGDSFTVSADNFNLGTTSSGASTCVGALAAEDLGLGDSTWLLGDSWMKNVYTVFSFSKTAVGFANLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V824</accession>
    <name>A0ABQ8V824_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="14">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_503596</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="14">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="14"/>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="3 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="17">
        <location>
            <begin position="318"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4479458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="423" mass="48279" checksum="134EEA54AD3DCA8B" modified="2025-10-08" version="1">MDRSTIASHPQIWWSNGIFFVSVHLAALVGMYCLPPTLVSWPTLALTYAMWQLAEFGITIGYHRLWSHRAFRASMSVRFVLALLGSAGFQGSIKWWCLRHRLHHRFTDDPIHDPYAATRGLLYSHMGWIFFKPTYTRMELVDRDDLDRDPVVRFQHKYYIPLALFFGFAVPPLIGALWNDALGAFVWAGLVSRLAVWHCTFFVNSLAHWDGLQPFSDENTSRGNFLLAVLTSGEGNHNFHAFPHDYRSGPWIHTWDPSKWVILLLHQFGLVYGLRQARDEDYKEALAYMNHKSLGGEPPKEDANEEQDSPSKSVGDSYQHWSVAATKLYVREHPERCFLLLNGWVVDVTLYLGEHPGGASLLRRYAIRPGEDDEAGAQKWLDASWAFDGGLNNHSRAAVKRMKELRVAKIELPEDAGLACVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9C7</accession>
    <name>A0ABQ8V9C7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_849814</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4472657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="20541" checksum="BBB93D8381CA779C" modified="2025-10-08" version="1">MNTYPTITIDLILDRVTIKDVLQAILDAILFHRLFGTVKPTTREVFGVTMPGVSDSEMGQLVEEKVELFWKGIEEGMSKRGQIIITFSEKRPKKSWFQVYVGEEDVPWEQWIINAEIKQPRDRDRQKFDAALSNTLTKAIHTMLTHTSSDRGRTAVPLITDATGISPFPIRIAVKIGGVEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9R0</accession>
    <name>A0ABQ8V9R0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NLI interacting factor-like phosphatase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_841247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="208"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="405" mass="44551" checksum="1FC8E17241C72752" modified="2025-10-08" version="1">MNSLKYLSRQFDVLASPKTLQSTPTKEEFRQLASSSEPPLKRVKTWSSRSFLVQGASSSAHPKRSRSSPTVSTLATTAISVTENKRRKHAESLISRIFYLRVLVLAWDSFRAAWTSLIHGGLRQSINKVPVPEEKSLLSEESSESSDDDSPPPTARSSTSLTSSTSSDSDPIPLEPKLRNPSITVHPPSDSVSSTRSATPTLGTRKTPFHAQKTLVLDLDETLIHSTTRPISTASNSGLFGFGARKGGPGHVVEVMLGGRSTLYHVYKRPFVDFFLRTVSGWYTLVIFTASMQEYADPVIDWLDAGRGILDHRLFRDSCTQLPNGSYTKDLAVVEPDLARVCLIDNSPISYRVNEANGIPIEGWTHDPSDEALLDLLPVLDSLRFTSDVRRVLGLRNATGSRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAN7</accession>
    <name>A0ABQ8VAN7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_839973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045564">
        <property type="entry name" value="DUF5910"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19287">
        <property type="entry name" value="DUF5910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="294" mass="32425" checksum="A2423A449390006D" modified="2025-10-08" version="1">MSSSTICLVQTHTPSYSSWSLISYPLLTTTNFPMSPTFVPSKLQTIAAVVLILSSSFFGVSAVPIDVSSASTSDTPSRHSHVDSSATNSSSPSRHSHMDAHENAKRADFLLGYTYVKTDVGTDYNAATQFTAVHFEEGPLGNAGEYLSPRPSRSHELKSGHTMECVVFAKKESVMKYGPIFVEAKAVNDQQKLEKYLAEKKFSPKSSVLIAHAVDAERKGELIMYIPGTFISTLGYDPARPAPAVDSLGFYVNCRPVEMMLYQPYKEISQWEELQPRLWVNGMTTMSTLKYSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB67</accession>
    <name>A0ABQ8VB67_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_774381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="16034" checksum="92E5800CBBDE7CE1" modified="2025-10-08" version="1">MGYWFCCDSRLLGYQCAVPRPDDTEKPIFYYKTLTVISSILHAIKLSTVHRVFVFTDNTNTVDMFHTLKARQLYNPLLLMAINHSICSNLQFCVAHIPGDENDIADALSWFDYARILQLVPSMEIYNFTPPQLVLGAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB98</accession>
    <name>A0ABQ8VB98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FMN-dependent alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_770664</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF140">
        <property type="entry name" value="FMN HYDROXY ACID DEHYDROGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045167069" evidence="4">
        <location>
            <begin position="28"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="5">
        <location>
            <begin position="51"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4481845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="400" mass="43976" checksum="A76D9E5657F6D549" modified="2025-10-08" version="1">MCLRIHNLIIWWLGFFLLTLVPRSCLSVEIDREGLPDTGLNTTDWETGTLPPLDDMWELNDFQIAAKNVLGARWYASYRTAALDQVTYEANMNIWKKIRINGFSFRDVSDVNLNTTILGYNFTVPFFIAPAAYAGHTNASAELSLARAAGKMGALYAPSIESTKTIEEIADVGFANQTMFHQEYVWSNRTLLIDDLSRIEAAGYKAIFLTVDNTGVNGIRVQAMRQTGELDSDSGHSASFTLDALAEIRNLTTLPIVPKGIKTAADAKTCLDLGFPAIYVSNHGGRVLDGVPTSVEILLDIRKQYPEVFEQMEVYADGGVRSANHIITLLALGAKAVGLGRSPIFANIYGEDGVDRMLTLLQAELQTSLQLMGEADVQNVVGNTTFINTKQVEVEYFGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBL1</accession>
    <name>A0ABQ8VBL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_437545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="4">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF11">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="7">
        <location>
            <begin position="100"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="270"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4486468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="360" mass="39755" checksum="6A6260C7401F7945" modified="2025-10-08" version="1">MSFLLSIFKPIAYISLPVILARTAISSSPMGLYYFRRGLYLGCMTAVATFGIVVAATMSATGYRYDVNWVIARTFYALAGTVLNIKVEVEGEEHLLTKPAVLLSNHQSMLDILFVGRLMPKKTSIMAKKSLQYTPLGPFMIMSGAVFIDRGNNARAVRSLEAAGQLMKNRKISLWMYPEGTRHMSKEPELLPFKKGAFHLALQSGIPIVPIITENYWRIYQEGFFGTGVVKIRVLPPIPTEGLTANDVPELAERVRDQMLDALRDISVKVEPASAEEPRDLPPPTTSSDPALFSSPSNTKEEGTFSPHDVNPEQVLEARTSSVMSIASSDSNHREQRSEPSENGTETEEDEGMILVGRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBM6</accession>
    <name>A0ABQ8VBM6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_868552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="52254" checksum="4F7DFB381A28745D" modified="2025-10-08" version="1">MDINTTTIHPAAESPPLSISDLETITLDGQEFRIRRPPGPQPDRTIALPVHNSGVFDVDYVDIYVMKRTSLAELCKKNNLGTVGKKAELQEKLIGFSENMIFPSLIVSTKMEAANTSTMKPKKLKGSALRRNVMMGLNPDGSSNVQVQRSKDMRPVEEQEKLLRWADRYYVAHPYVPPEEVSRMLKAERDAKMESFPTTSPMLTTLLIPTPSPTLTTLLIPTTSPMPTTSLMPMILPTPTTSLTPTDASSLPSALHNNDVIMADAVALSVLPSTARKAHRRVEEKLFEIILANQNVLRFKYHDIPEPLLQLSFAHDIIRLDHIWDDKQPNWDPVDCATVSVINGVPVALCYWQQVYKGKKDQRWDSIKGVWSEWRYVAERYWSSTSEEFWSEFQTDAGEPMNWTSILERLRELQINCDEELAERARAEYGSRFPVLFSYRGKVMLKSSSIANRYLSLQNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCL2</accession>
    <name>A0ABQ8VCL2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fruit-body specific protein a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_920988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4487455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56082" checksum="231D01851358DFE4" modified="2025-10-08" version="1">MLLFPYYHLTPALLVAGNTSTNHRYGYAEHGSVVYSASQGIRTMEWDSNEFTGTTIDFDGIAYAVFQLDQISGLTADSRPNSPSISTIATALDGEAVNPAVLTPRNPSSSAVESRLHWHRRTKRDYVQIFEGAETGLEDPDASIVGVAYLTYTLVNNSTYNVDDCLEFCDRTLGCVSVNLYYEYNNLLLDHIYPQRSNLKCVAYGDVHFPQSKLNFGGMSVSGDLIYIQESSGWVTKSYLNPSAPDGYDALPDLDGANEAFGYMNSFFLTHYDVDACAAICNNWTPDDLGGSCKYFNIWRAVVGIVPITYTCSIYYIPADPSTAVYRGQGNLTVTESRGYKRKTYILDGGFEYYTCDEPNTAFCFTHTTETWLASSLWEGYYDASIFHYKPYAHSGNSVAILGSAFGYDEYPGTLTVASSLSTEAGVRYIIEFFHSRSGEGMEVNGFVEVYWNGDLVGVIYPAYSQWEYYQFEVVSQGNDELDFRGGRAPVYDYIDDIIVMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCQ4</accession>
    <name>A0ABQ8VCQ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_836798</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="6"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4487451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="24417" checksum="CCCBB2FBD7A5B873" modified="2025-10-08" version="1">MPPPKSKGGKMLGLINWRLKVTINDGRALTGQMLAFDKHMNLVLAECEEFRRVRPKKKAGDESAPAEQELKRTLGLVILRGETVVSLSVEGPPPVVDDDKKNTLPVGPGRGMPAGRGMGMMPPSALSNCSIFSFRFDVDSFQWVLHPWLLRCHFRQECQVRHLASVRLVSRLVCLLLQHQGLLDLLLASNHPLNKKQTKNYTVVFHALVALSCSILHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCT4</accession>
    <name>A0ABQ8VCT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="35595" checksum="F4903A398BA03767" modified="2025-10-08" version="1">MAEHLDFDLAKIPAPDFAGETYAFMRTALIADANTPEVSTNELAIQRLKEQWEAHIGGLKAQYQTQLQEAETLREQNRQEATAAEELAEAERQEKEKELLKEAEKKRLPIYSFQKGLGVDSIPLQLHPYAKKMMTARKYVPLWYFLPDAATEAKERTKESLDTNHLQFAVEDDGPVAGSTISLVGSHSVRASPNTIPDSQLSWPQVTRAKSAFLNALQLGTWPDTFIAMFAGFYSNMDMHRELQEQDGDRVMAHYHAEMRLAWYDAMERKDPFDLSIISDGVLRESHLQIAKQKQEKSLKGMSPPLHQNRDHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD83</accession>
    <name>A0ABQ8VD83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras guanine nucleotide exchange factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_840452</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF348">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="556"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="790"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="93"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="439"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="529"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="536"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1062" mass="117422" checksum="4B457C0A0BA21785" modified="2025-10-08" version="1">MAQPLEDTHSPTKAILSDNQLNNSLPSPAGSFVSKESYSTAISSSTHVDLEIHPITKSTPDTNSSSLILPQNLRKSISVDSFVHYGRETLSPVVTRPNRGHTGSALEPPTGLVGLRREFNHVNQPGRSRGDSISSVKSSLAEDSDADRSDTYNSSTERYRQTLKPQDHVRSFVPGGELPLPSRTPTLSTTSSMSSIMSSTTSSSTQEATPSLRSASSLQSPARPIASAGRTRSGSLGVYSQNTRRIQINTQIASEQNQAITLAVVGTAGCGKSVAVRKGLKNNNLSDPSGPLPGPHPSIRHTRSTGTFTRDEGVECPLHVIEVDVISEILQSPITPLDYLPEALKIDGVIVCYDASDESSFRPVEDLLKAYRSLQFPVIVIACKSDLERKVDPLSASEILLQYDVGLVEVNHNENGKEKMKRSFDYLLRAILRERRNGSSRSRFSEDYRNPASPEIVNASPSWDRPDGSRTATPTASSASSLNHIPIPGPIVLQSSLPTIPASRTTSVPNSPTRARSTGDLLCEQTSSIDKENANVDHSPTTELSPPTKVESKDKEMRPAQWATLDELLDKLLFLSVSGDDPTFVTHFLLTYRRFASPRSLLLAMQKRMRQLDNPSGDPMFACFAQMKICHLLEIWIRDYSYDFAVRGTAGALSALIKSIISKTYLLHYGSDFLPFLEVLPTLVDRDSSWALKVDDDAASDDSYSLLEDDDESIKSATKLTSSPPEDLGKTSVSIPSRSRKSSIPLLSAKVLFPSSGGYNGSIDSDNAEFTTKQQLRELVKLANEVNMIDSGEMAQEITRIEKQSFLEIEPRHWLHFTLVSGKKDPETNTIARFNAMSNHLADWVVSLILCHDRPRDRARQIEKFVDVAQKLRGLNNYSALRAFVAGINNSTFAGDQTMEKFKQRSPDSAKTLRSWDVLLQAIRAHRAYRLALRNTKGATIPALEVHMSDLIRAHEANDDVKSGDPTKIHWGKFNMMGRFITSTTQCQAQCRSATDYNFPERQHIGNLFITKYLMDDEMQKSRIAPPDNDFEEFSGGFPVATTATQYKPPRDMARLRRIFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDE9</accession>
    <name>A0ABQ8VDE9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_771945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4479434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="19222" checksum="613F8E9F45DE24DF" modified="2025-10-08" version="1" fragment="single">MTPLPRPPRDVVLDDTVLDTIRKNPHLFNITTPINVDRFQTLLTSHPNQDFVESVCTGFRQGFWPRASGDKPGTPLVLDRTRKLHDPRHFAFACEQRDKEITERRFSPTFHSLLPGMQSVPVVVVPKPHTDKFRLAVDHSAEPFALNSLIDRKDVKVKMDNLHDLGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDZ7</accession>
    <name>A0ABQ8VDZ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_384766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="71303" checksum="26CB5FF4300C476F" modified="2025-10-08" version="1">MVLPTQPSFMESVSIAETVPIELWERITYYANAREDAFLGPPRDIVNICLVCRFLNSAVNFGDNPSLYARLFRFKFDYRAPLRRFGRDWLTSRSIALEFKKRIILLKQVRQKECSTQDLWTCYLMILENDGRNERQLIEWAHLYGYLKHETCVRYEATLDSTINWFKDTEATSLLLWLWWMTFSRDDVRIENSHVRDSLVYHLLHNLIVASFRYPKLYGPESHFKIPPAGCIWSSTPPTPVARVNHFSKELYLATPLLSVASFLIWTLRLETIRENTDFDLGAISSLPLDREDAIAHRTQGPTQADILKFHQTQIRAPTHCSLVLCTFFEEEILTQECEQSVERLLLSSDSRRYDQDWYRSWTCFDSLSITPSNHNAYVPGALLGDWEGFFVQTSLDDHIALVDDPNHMPSDPISLYRHPLYFTLKEHHCFHPVVPIGPGTDCIGGEDVLNAWLPQGLKIQQYENEIEVFDPVAQRNVRYETFLPGGLEGTKVRLQSEKVPGTSRKLGNGYNYTNSFTLSKNESLNDILVTGKTSEENGAAWGHYLFIGRIRLWDGLIVLLRTPRDPTRSNLGRWLFRGYLHDGNFVGHWRETSTSPNLTGYQGEFVAHNRDGRNCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE10</accession>
    <name>A0ABQ8VE10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1688-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_896000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="440" mass="48694" checksum="CE740E22528B1BB5" modified="2025-10-08" version="1">MSLLVPNELSLQSKAAYLRTLPSIRERCTRVFELAQQGKLEYFDYHEEKEKQVVEYCRNIITRDFGTDYSRIPPHGRWRHFDLGLNRVERLLNKWTTELGTGENAKKESSKRLVDLFVVSVLLDAGAGKDWVYHEKDTEGNYSRSEGLAICSLHMFEDGLFSGEDGQKCRVDATGLSKITATSVAQHMQVSETNPIVGLEGRTSLLYNLSTALKSSTEFFGEEGRPGNMLDFLERQSKISESGTRLVPLAALWNVLIDGLNPIWPASRTKLGGVSLGDVWPCEALKSTSSSEGDDLVPFHKLTQWLTYSLVEAITHTMKWEFVGLEDMTGLPEYRNGGLLIDLGVLTLKPNALPIDETSGLPKAAPDDPAVVEWRAMTVVMLDRIATALRTSLNLSASDLSLAQVLESATWKGGREIAQTKRGEKGGGPPLELVSDGTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE38</accession>
    <name>A0ABQ8VE38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_724973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25413" checksum="66657721A35AA77A" modified="2025-10-08" version="1" fragment="single">IVNSLIDNGAHLALIHPDLVCRLGLSRRILKKPEPVCAAFQSGSNQSIAPLTEYVLLKVSSVDGSFTSRNVPFVIAPNLCTQLLLGLPWLTHNSIVIDYTLRSCTHKPLGFDLLNNKPVTRAFAFKTKSIEKIRESLVKLGNRAKEHWKKLLIELKNKCSTIRPTCPPSCVSSTPTSSEVIASIRSRIEDLATLETLKGHESRLKEKYRAIFEPIPHVDELPTSVTAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEQ9</accession>
    <name>A0ABQ8VEQ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB box-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_833103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="8"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="202" mass="22300" checksum="9EE11A5135F74973" modified="2025-10-08" version="1">MDLFLIPNNPENCALVSINGVAHYQVSTTKTSHSQRASKIQRPAESEEDSIVAEIDWGNWDRPTVVRSCPLVRAKSVSVLASEFLYKKHRFSSSRYFVGDDTIEYRWKFVKGVGCVLMRDDTKEEVACYSFAISKEGLYAGEKKSRLTIQPCSVELDLIVVSFLIMLKKRREKVGPAGDFALCAHDEDPQGDGGGDGGSGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGX8</accession>
    <name>A0ABQ8VGX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_834656</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4489814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="531" mass="59267" checksum="9C221D2804E5DF81" modified="2025-10-08" version="1">MLSLRKHVILCITSGEPIKPIKSPSIFQSLSLLAFVACYLVLRASARSARTLPGPGSYPIIGNILSLPIQNPWLTFTKWKVIFGDVVHLRGLRQSIIILNSKQAMDDLLDRRGAIYSNRPQFTVVEMMGLDRGMPLLQHNDTWRLQRKLAKTALNNDAVKEYEDTQAEVAALMCLSLLTDPTHFREHIRLAAGRIIISITYGLPVSDAQHRLITEMDKVVPMLSDATMPGTFIADLFPIFKDLPDWVPFMSFKKEAKKIRAIVDRLGEIPFAQVQKEMAAGTAQVSFTQKLLADRSGEDDESQYNDAVKWSGGSMYGAGGETTHTSVLVFLIGVMQNPAAQKKAQDELDEVIGRDRMPTLEDRAQLPYVDAIIKEIMRWRPAFPLGIPRRVDKDDEYAGYCIPADSIIIPNVWAVAMDVPSGTKYPAADFAPERFLEEHPPVDPALYAFGFGRRVCPGRLLAENSIFLLVTSILYCCTISTPSNHGQKHSAEAIEFSTTGLVSHPMPFSCRIEQRSADRFDVVKRAVSRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH11</accession>
    <name>A0ABQ8VH11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60s ribosomal protein l7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_830367</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="5">
        <location>
            <begin position="182"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="33334" checksum="BC8DB918B16F29DA" modified="2025-10-08" version="1">MPLARPTRFGKPPPIRKRLPADTRRKLPRPPVNLRVREYAPCRLSDHYHTTLSDNLMYMNYSHILQSDLPPKPPREIRLRWDPSNPYAKYRKNHPVGGTQWSKIPPEPSTPANITRLEAVQIHIMSKDALTSRSNLLGVIAALRALSGETEAGGGALAKGVKGVEIVLGKKQVGGWIRAGMPAGAKVTLKGSAMYDLIATLAEFVLPRLREFHGIPMPAAVSSYTSYLPASSNAVKASDVAGVVSFGLPAAAMGFWPQIEVNQDAYPKMYGMHIHFITNAVGVGAQERARALVSGFQIPFVRKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH12</accession>
    <name>A0ABQ8VH12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_833657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="17"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="33215" checksum="EE40C41A2911407E" modified="2025-10-08" version="1">MDSNTLKEELQLKIITYVTISFLALLIYDWFISLSREVIRVWQSRWSLVKVLYLYTRYAPFIVMAISAQERVSSTCNKMTFTTIFAGFTIGISELILMLRTYSIYNKSRRVLTIFGLSWVVISAACVWAVIRFTASIPASEGTGSSSSCFLPSESNVVLVCYISLLAGEWVVTLLTIWKTFDLYHKSGFHFSQVVSMVYCEGLFYYLLILPFTIANVAVLFSATAGFLALLDAPLTVMHSILCCRLVLHVRDVSKHRMEDDDGDDEDDVLPTFIIVTVMEPYMSKQPQQHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VII6</accession>
    <name>A0ABQ8VII6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_828027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="64"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="40030" checksum="D1F6ABEA8778FE3E" modified="2025-10-08" version="1">MAKRKNISKSHSDIEPYPKRRSNRLKCALADVKLAIPTYRASEIVSAVASSSFEAQSTDAQKNLQDLLEMPEDIFREVLRHLDPQDLLNLFHSASVFRTFLLHKSSAPTWAAARANLPGLPPRIKSMNEASYASFLFDKHCEICQVPYASGQNTFWDIQMRVCSACQFSRSIFLPENSFEFQPQPPFIDKKEFLSLVPTMFCGSLGGWMPKIVQNHLTQYEEMVTDEDSFKQWRARMNKEREERRKWCDYHYDWLRIDAERCERQMEQRKEGNLEIWRTRYKDITVRLIALGWKEEVIPTQLAQHPQVKKLQQLTDEEWIEISPTLVEYIKTQIQDAGMVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIW1</accession>
    <name>A0ABQ8VIW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="353" mass="37945" checksum="1ECED2D40BC457B9" modified="2025-10-08" version="1">MDPPLATEFKRGVSGFHFFGDTANFSATSQGHGVTDSAPIGSSRGCRRGSEMQLQPFDKMGYFLRSSVAKNPSKPEFKPGRTVEPVLAPPGFDFLSLIRACIPQSYGPIGEEDLGVDRDNPDFGSSVLPPTGPLRECAPTHKQTRDNVQRRRNRERRWINCGAESNAEVQTAASFPLNTLPIIAPTLVSKAPPLASPSPSPLCPSPSSLRNSKRAGKRKRKAETEPVQAGPSKRTIAHVLSAIEVDLEAQDFDAAHGAHTAKPGTQKQRGSNADIQRRYSVEDLVALGFRHIPWDGLTPYPLINPLGRVIGVLAGTPGSGYAEDLLRASDLILQEGKQAGLGAAAPNPVSDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJL9</accession>
    <name>A0ABQ8VJL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_826244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047047552" evidence="2">
        <location>
            <begin position="26"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="719" mass="72755" checksum="AB43C95FAABBCB62" modified="2025-10-08" version="1">MAFLFSGSTLSILLAGSTIITSVSAVNDWDTPCFDGTCQYSLTALPGQNGSGTMQIWGSSNAISDITTAAGWEILNCSATAMAQDIRLVCMSSDTEGAGCDHLFQAGGAEGKLVRLPEDCGMSPFARVAQSYVSGDQSIPAGISARFVRRAGSGNSSLPQVQGLSLDTNFSAVDPSRYGNINIAVQGANFAGADVNGTLVSTATARRRSGLSYSVSARDLSDFVGNAIDSIKSLSSFNTTKTISLPPVSVDKSATLLNKDIKCGNVDINVDLGVDGKAQAQISLGVAAQGTIVPPDLNDFAVTVGMDAVIDGTVDLSAGVSTTFDTGKIQVVPPLGIPGLDFPGILTIGPSFEVQAEATAKLDIAADLKVGIVYNISNAQLVFPDKNNQSGGNFGVGDTPLTLSVTPSVKSTGSLTAHLIPSLNLGIQALDNIASATVFLDLDASATMQLSLDAVDSASVSVDNGESSLNSTTSTSNSTSTASSTSSAVSAYYSMSSGSNSSASSSIDSSNANIYYYNFFRRSASAAPTTTKPTSIPQAISSAKLAASSASASASKATSSGVSNSTSSAGNSTSASTGNSSSSSSTTTTSSTGLQFGGCVEIDTGLAVNAGADAKFFDLFDASTQVPLFSKEFVLFKKCFGNGNATGSSTRKRRSPSSSFSSLPHQLTRLSNRAAAAAPVAANSTASSSLACLASSAVAPQPITGTIQIAGVTVTIKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKC0</accession>
    <name>A0ABQ8VKC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit M</fullName>
            <shortName evidence="5">eIF3m</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_761207</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit M family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03012">
        <property type="entry name" value="eIF3m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027528">
        <property type="entry name" value="eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040750">
        <property type="entry name" value="eIF3m_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF2">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18005">
        <property type="entry name" value="eIF3m_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="197"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="414" mass="46220" checksum="009A7337518D1865" modified="2025-10-08" version="1">MSQTDSVPVFAEGTFEEQVQELVNYLVRNQPDEERAASIRPFQEALASTEGQKPLSEDVERRRKILVMILTSITGLGHGQEKEIEGFFNLIYAHLFSLFSPSSQEAKQHTATLLKVISSAPSEQISIKYRILSNLFNALPRNSSLRLSVYKTILQIAVADDSINILHLSRSDVEKWTNEWDISPEDKSAFLENIVDAYAKSNQLIQSYDYSLLHLRSLPSTSEAARDTSIKVIASALRIPSIFDFDALFKIDAVVANKDHELFSLLQVFLNNGLSEFKSWEASHAGVLEKYDLGRAQLERKIRLLTLASLGFKNIGTNLPYAKIAEAIQVDASEVEKWVIDIIRTGLLSGKLSQTTQTLYVTRSTARSFEREQWQALEQRLSSWKSGLSSVLEVVASAKRQGGHVSQTVAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKS8</accession>
    <name>A0ABQ8VKS8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Manganese lipoxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_831570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoxygenase" evidence="6">
        <location>
            <begin position="243"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="222"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4492455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="918" mass="104472" checksum="AC34523523497331" modified="2025-10-08" version="1">MSEHVDQNDVVMLLMGSSGTGKSSFIRLLTNNTGVKIGNNLDSQTSDVQVFHFFDKVSGRNIVLVDTPGFDDSRNDITDTAVLKKIAEFLLKKYDEKRKLNGLIYLHRMSDPRFGGQASRNLKMFQNLCGPNAYGNIVVLTTFWDRVSAEEGLTREEQLKSTFFSNIVAGGARFMRHDRTAQSAREVIAHILTLSPTDVQIQEEIRVDGKGLEETAAGLVHREEVELVLEKHRQEIMSLGKEISSIKQDNETLRRELEEEKEELQQRLAQWENEKADLKKGLDDSLKSRERLENQYRSVDKVRSATLEVLQVKIKEGKTSNMVVEQMSEEATVQRVYNSNQNDLFRFTYSDKYPPYMKTIPVDDRKNPLRIFDFASFAETTALLFIRPELLWSKIRNLAPDLTNCDSMQALEVHNFRLHTESKKRAKSDSNARDMYFSKNIGLRRDWYTDAAFGQQQFTGTNPTTITLAPRRWIDEFTSTAQAQGRADIINLLTKKAESLYVQDYSDFRSSIGVSPGEKIVTDGRHGCSSVALFHLEPEGKLHPLSIVLDYRGSIQESVTIFNRRITSNVNGDEYMDWPWRYAKTCVQVSDWLRHEVAIHLVNTHLVEEVIIVAAYRSFGPKHIIFRLLEPHWSTTLSLNKAARETLVPSIIIGMTGLTASQTYAFLKAAYDRFDWKGLYVPNDLRTRGFPVECLDEPKYHNYAYARNISKTWNIIRKFVATVLSKEYSGGDAAVQRDASIGIFCDEVRSRKGGQLTSFPAIETLDELIDFVTMCIHVAAPQHTAVNYLQQYYQTFVPNKPSALHFPIPLSLSELCSFTEEDLLSALPLKRPRDWLLMAQVPYLLSFEVPEESTILHYAETTSSSRATPTVIRSAAQVLASDLRVFIDTVIQNSNELDDQQTPYLVLDPSRTAISILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLB3</accession>
    <name>A0ABQ8VLB3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_827259</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="29"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="172"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="115"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4495594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="54430" checksum="38CD3E201EB3692F" modified="2025-10-08" version="1">MFTRRLQGKRFLVACLHTSRRVQNSRKVIEKFKLADIGEGITECEIIKWNVKPQAVIQAFDPLCEVQSDKASVEITSPFDGVVTELLVQEGQVAKVGSNLCLIEVVKEGAIGISPNVAEPVNTSSNPDTNSLPTIESEQESGSSKEFTSASRRKHPMDPTFTPDAKSNSPIFATPSVRHIARQRGVDLAQLAPGSGKEGRIERRDIDDYLAGAATTKAPVALQDDQDVVVELGRTRHSMWKAMEKSLHIPHFGYSTTLDLTTLHGLLPSLNANIPPHFLPPSVIPTLPLAVSPSSVYPPSPPPEIPPSGQYTRLTYLPFLLKTLAKSMFEWPLFRASITTTDPSSRPTLTIRPHSDISVALSTPNGLYTPTIQSADSHSMYALFSQLKYLSHLGRQIPCGLTPKEMPKRGGTLTVSNVGAIGAGDFAAPVLVPGGGVAIVALGRAKWVWDVDRGDGSGERRLKLGVSWSADHRVIEGAELAAFVECWRGYVENPARLIADSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLC2</accession>
    <name>A0ABQ8VLC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-fucosyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_233012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="48304" checksum="AA272CD505D70433" modified="2025-10-08" version="1">MKSVSSYSRLRARVILLAVVVALYLLYYKYSNNDNDTSNYSPHLLYADLHQKEEQTGRKFLESLHLIDSQKDPKFVLFRQHEGADFGNQVQEILLHHHLALQSSRFYIYQPFDWKSRNEHLPLSAFLLGATEERAVPASFFEELCPKGSEDVVHIKIQASQEELWDTALSALRREERCIVVDNPIVDTTYLSSPAAQAIWPLFQKYLARWFRWSPQILDIVERRQTQLNLRRHFSNLKGEPYLALHLHRKEFIDYCKTAAHQKAGFTNWANLPSILSTTLAPQLNSRNESSVMEHCYPSLFRVMDAIDLQIRRKPYLRTIHIIHDGIALTDLWKLETALKNPERAHRAGWTYGPIKSLTHSAMLPRESGDSDFLVGADAELARRAEVFIGNGYSSLSSYIIALRMGGDLVAAGIPEDITLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLF9</accession>
    <name>A0ABQ8VLF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_258234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="221"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="352"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="425"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="517"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4496736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="572" mass="62149" checksum="2F00D6252A2FBBCF" modified="2025-10-08" version="1">MSGLKNSPFGKRLRASQQETDDGTPRRNRPRINSVFGVSPAGSATPSLDSRPTTSSDSSGGPDSPVDPPRVARDYGDRFVPSRDTGDMRTSYHLMEQEPSTPSKKNRIIPSESDALKEQANALFSSILHTEVTPPSPHRPSSPTRPPVASTSAAPPSTPTRRRLFAYSSPSRSNPSTPSRRLDTPTDEAYSMSPVRAQSRQLLESPRRQLRSVCKTPYRVLDAPELAEDFYLNLVDWSSTNVLGVGLGSCVYLWTAHNAAVSKLCDLAESRDTISSVSWVQKGSTLAVGTLSGTLHVYDASTLQLIRTYPQAHGQRIGAIAWNAHILSSGSRDRMVHHRDVREADTRPFKRCQGHKQEVCGLKWSGDGGPSSANLASGGNDNKVCIWDLRGSRRAAAGLPNAGRPVPGTSSGDDAGAGDIPLWKFHEHTAAVKALAWDPHVSGVLATGGGTQDKHIRFWNTGTGTMLNELDTGSQVCNLIWSLTSHELVSTHGFSSTTAQNQICIWKYPTLNMVASLTGHTNRVLYLAMSPDGETIVTGAGDETLRFWNAFPKKESSEREKDSRLDYGKLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLP4</accession>
    <name>A0ABQ8VLP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome biogenesis protein NOP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_762788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="28039" checksum="AA4987D52C711EBF" modified="2025-10-08" version="1">MPHKRAKRSVREQQRSQKSLDLAPSHLSISQEPIPKSLARALNAAKVREEWRKRKTEDREEEKTGTDRKKRKLNGKEQSKISKILPGESLQHYNKRVENDMRPLVKNAVHLSKIAVRDARRQELTAKAAKQAPKLKRDVRDHLDEPANELISQVSIRPTEFETLSTSAPRRLNDIAQSPPELSRLPRGVSTAKVANAKVDRRDGVLSLAQKAMMEEEREKAVARYRELKAYRRKDYNEEETED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLT5</accession>
    <name>A0ABQ8VLT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_742053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="2">
        <location>
            <begin position="249"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="407" mass="46795" checksum="5075F985BD256C28" modified="2025-10-08" version="1" fragment="single">VVNELRTNYRLFESAVTTAYTQDADTFLLQRLGNDIETFASIVDTQESIFNENSEWQTLRTNLQAMLADVWTIEFLEWAYTQRTTSGIAEYLGVARQTVRQALLDYGIAQPGINPFPPSEVHSEHTDSENDPVLDQDGTLPQELPDDVQDAAASIASSSSSSSYLSNLSDEDLDRVVKALRSHYARAGIRMLQGMLRRLGHIVPYERVRLSLIRIDPIHRVFDRIRIRRRQYKVPGPNSLWHHNGHHRNSVQNVRIERLWVDVSHYVSQHWHDAFTALEVHHDLDIQNVNHIWLIHHLFLCQINDSLAFWAESWNSHWVRENNGPSRSPEDRFGFDMFVQGFQGEALDQFAMSDEELEVFGIDWEGLEDEVLLRSLRKNYAHEDGTSTSLGRHGPPPNLNEVVVDPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLU2</accession>
    <name>A0ABQ8VLU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="410" mass="45496" checksum="C705D91DCEF2F297" modified="2025-10-08" version="1">MHCLQPLDVGCFSPLQTAGFNRCDDILAETGVSMDLCDVVKEYMAVRDLSFKESTIKTAWQKSGINPLNPGIFSEADFAPSIASSTRMQLPASYPTQLPHGPDVASSDAEFDGKVLEGRERRRNKRGSDSDYCTDESSLESSDKSDDSEEPSCHCSLSPPQDRNVNMQSTPLTRSHQISNQQVPMTPTAIPLTPSISLTPAPSIPGPSGSHFHATISLWEIELMCRVADLERDLAITKAERDAATVYTVYSSQEASIYKHHLNSHTNKKDTSKRFPTLACVVTSRDGRIQAKEDDVRRQAKVQANEERAQKKKDKERDDIIRRAAQEKEGTEFEGSLNSKNKTELEDIAFSLGLDIDATAIILKIRIDAHFNATPSLKQDPQYMGLFTCKRKCAPVLSENNDIWPSSSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNB5</accession>
    <name>A0ABQ8VNB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dirigent protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_237760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="24189" checksum="D4FF003A71A342BA" modified="2025-10-08" version="1">MRVILQNVSGFDVGLLLILSALFTVARPFSAPVSIIIPPYKLLLLHCNPFLQGTSDDRNPDLLDSNSTFQSQPNVTFSGRSTSHQETMEGKVTFGPPNNRGLSDNENTWAQLAVRALIGEAKNEHDSKHDYHITFDFLNQAKYSGEVGIYEFNVALEGWHWLKPGAKSSLAGRVHWGSGTQKLPGGVIRGKISGFLNYIGPDQTNYFAANDRPVEMTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNR4</accession>
    <name>A0ABQ8VNR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_762779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="130" mass="15330" checksum="0FBBF1425E353393" modified="2025-10-08" version="1">MAKSSQVKGQDEVIKTFEHHARLWEKLPEYTELRWDVFPWPMLNKPSSPEDITYAAVYGYLSSPYHPEKDRPQKDRIKEQIRRWHPDRFETKLLPKVIEEDKEKVKEGAGSVVRSLNSLLTKSNTPSFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNY0</accession>
    <name>A0ABQ8VNY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_790843</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10524">
        <property type="entry name" value="SET_Suv4-20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="131"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="292"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="491"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="666"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="738"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="821"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="872"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="936"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="389"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="510"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="681"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="821"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="941"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4498103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1068" mass="118428" checksum="0538729290B0D619" modified="2025-10-08" version="1">MAPNSSVHALSPREPLTWRPTKIMNMRDLSKDDDFLSHLLVEKLGTGSVPLLVHKMDSSRRLPKVSPHDLIEIVRRLVMFKGPLQHAVRNAVDDLVYLTPIRYYLQNYTQKQINAFATHASRYFELYHPSGSIEISHTSRYSHRTGKSELCILATRNLAPGSVITELKGSMANLTDEEDRELKRTDLRNSDIRRDFSVIHSKSMKKNHLFLGPARFVNHDCDNNCELFREGRYITFRVLRPISIGEEITAHYGDCYCMSWSVICCSCFDCLGFAVGRKNRHCLCETCEKKGRGGYAPDHTDDEIPSDSAFSDSDSDGSSSESDATSSGQDDGAVKRQVNLNERRTRRGVYAVVTKEEDHSDESDDEDGSVKPLAGASDIPSPGEMEMAESTSDLTSIPSSRAVSNCNQAGPSCLSSSTSELTPISRSTSSLSSLSSFEGTSSTHKNSSYQSIIATRRQKAQAEAAALVNASATLPEDSSLSSVSSLRHLTQASMSVTPGKGKAKQKEQIRASSTPMRSDNLQATESGKMKDEDPRILRPRPSASVTTPEAAKEINLKTEIPRGPDGKPLPICAICRNILPVISVDHQIVWGLGLEKDSKKKKAKQDCPRCMRHYAIYGELWPRRVPLPGCTSTFNTTPREETTPIEFARKVTHKVLPVLDRKIAAVASSKRKRSSEGPVAEEEHEHFAKKPKTSVDRTVLKKRIPIPLPEGQKRKRGRPRLMSVSVTVPALPPIVKMEDNEEPLHPNGFKSQGRRMNGRFERKLSSSSPEKGYDLDKSPKNALAGRAQRALEREKAKQIVERELLVKRGLSDGEIERITKKGKWDGSNPHDKEPPLKKVFPKRSTSFRSGNLFSRPNPMSFAARAWANPLVSDDASSEDEKVPDTPEDSLSPPAIVEVELEDWDRGPSLIVTAPAVPPAYKPSPFSFARRRWSSLSASPIEEPKKSTSELRPNADARPPLNMERILGHNSSSMSSTFKDRTSSYEKWNLNHGTYSSEEEDTPNLFTLRVSPLHGGESNTRPLLLQHTYPSDVAYTQGLAFTPDLSSAPPTFVAPTFNDAGWESDFSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP60</accession>
    <name>A0ABQ8VP60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_916812</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="6">
        <location>
            <begin position="257"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="640" mass="71815" checksum="22579D27750397E1" modified="2025-10-08" version="1">MSEQLQGKIGNDDTEQVPQEDPSAPLISRLGSTLSDSSSTYNMLSAGLPTITSNGSTTPSDGDGIISNGLLDLYSDPIHTRFFGPSSGFALMKKTYDLKSEVMSEQNIPLHALFQRPEYWLQVQPWERASRDQQIPKYNFPETSLMLSLVSLYLVSVNIFFPIIHTPTFQQAIAEGVHFRDQHFGATVLLVCAIGSRYSTDPRVLHVPDSELSSGHQWFAQVRTLRQSLLEVPSLYELQQCCLSILYLIGTPEPSQSWILVVLGIRFSCELGLHRRKPDGHKWTFEEEQAKRVVLVTLDKLTASFLGRPPAIHDEDIDADLPIQCDDEYWENTNRSLAFKQPAGKPSVITAFVSYLRLCDILDFALRTLYSTKKSQLLLGLVGQDWRERVVYDLDSSLNEWISSLPPHLRSESGRQREGVFAMQSAFLYTAYYHLQIYVHRPFLSRPSSRALPSLSVCMTAARSCARVLDCQQNGSVASLPHTQYAAFAAGVVLLFNLWASKRAGTEIDQHKEIQNIWILLGVLEAQEAKSASAGRFWDMLMELKRGYDHPTAETSADEVQEMNSLDDTHLGPQGPPIGKKTSSIDKTEHREHLTTNRFGHGMDVWSIAPPGFTYDEWVNYIENMSGMGGSFEQEKAVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPM5</accession>
    <name>A0ABQ8VPM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_918352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="26693" checksum="878AB04E63A3F135" modified="2025-10-08" version="1">MSYSVSNTASPLWIGMHIRIIKGKYKAYHGYVHHVNPSNSSISGLKIVVELSAHTSNGTNSLVTVEYDDIREFEHWRTLAEVQPLGLYQTSYNLRPDYFPPQLDVPYIPQPGPEVVFHFTTPFPTALDVTLDTFWGVQPLEEIKPQDLHWILHPAFNQKSLHVFIDPAHSLHGGYAKWVYVDNGIVSLKKQGGHTEQLELAVIQRPMVPPAVLSYTSLTHQFLGYFQGCFNLRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPU8</accession>
    <name>A0ABQ8VPU8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_152987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046183382" description="Secreted protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11675" checksum="8A52F01FC861EEA7" modified="2025-10-08" version="1">MRVQRVCNDILAFFVFSLSHISVPEVWGLELQLHNWWRQCCTRPIDVQSQIVQILCGRIRFNGAKAPNLSIPRSWCAKSTTARQQAPARTSYPHLQPNAAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPY4</accession>
    <name>A0ABQ8VPY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_740939</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="110" mass="12250" checksum="2756DF90680AF094" modified="2025-10-08" version="1" fragment="single">LHLDADSWQSSAATSGTMFHQFKFPAPILTSLTLVTDGRGITNGILPQMFSGEMPSLKKLCLKHLTAWPRGYFQSLTHVCLYDQNESTRPTMDEFLDFLASSPSLEELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPY6</accession>
    <name>A0ABQ8VPY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ATP synthase epsilon chain-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_134534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="73" mass="8084" checksum="140BBBB07F91D841" modified="2025-10-08" version="1">MSATWRGVFTFNKYSQITASAVRKSLKESQRLAAEKRGITALRYQVWENGKGGEQIILDPAQDSDPKANKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQM0</accession>
    <name>A0ABQ8VQM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CrcB-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_756262</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>fluoride(in) = fluoride(out)</text>
            <dbReference type="Rhea" id="RHEA:76159"/>
            <dbReference type="ChEBI" id="CHEBI:17051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:76160"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="FluC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259:SF1">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4498677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="373" mass="40878" checksum="BB2B488D032566B9" modified="2025-10-08" version="1">MFPLRTLGKKHEGGLSSRRNSHREIHTSVHDVGSEVSIASVDQPPPSRQSSHHDHELHRTRTYHPFAPHVLILLMPASIFGVLARLGLVALTTYNGQSIFPLAYVQGLGCFVMGFGLELKEPLGNFYPPLYTAITTGFCGSLTTFSSWQLDVFNSWLNSEHAEHAGLRTFLDGLGKTVFTLTISLSSVLFGSYMARVIYPFLPTLQPPSRTVRYIISILSVLMYAATLPAYFLLPTSYRHQATAALLFAFPGTLIRYILSTLLNPLLTTFPLGTFAANSTGSGLLAAFHVIQSIASKPISPNECSLLQGLDDGFCGCLTTVSTFAVEIRGLQGWERPRYVLMSWGAGQLLFLIIMGPSLLSGSVRKQLMCSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR05</accession>
    <name>A0ABQ8VR05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_816572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="705" mass="78739" checksum="4B80F22891629A5A" modified="2025-10-08" version="1">MSELDITVERLSAQNTEATTTPGSTTDTSTPTTSITGLDVEKLAKSEDTKRIPSYRSIFNSPPPIKYPYRPNEALGDIPGISYALELFLASHMVESEDYCNKSDVNKERLYFATGYGLIQCVKALMSYADEDILSGIEHTKQGNLIATQHRKKAAFFTSRLAGYVVSSLNTTGVGFIRSMTDVERHAELVYAESLFEKALLGIVYSGDWLAFIKETLNMRTTIQVYRTLHKYINTMDAESVARGGLAEDPSIDAHFRSGVYLGAGMSSLILSLLPTKLLTIVEMFGYKGDRAEALELLGRAGGWSRDSDEPGVSAAQEGVRRTICDMALLIFHLVLSSFTFDGVDVTMAQKIINWNLKRYPDGVFFLFGAGRASLARSQPLRAIGYYTRAMEVQAQYRNLHHISYWEIAIARMALWHIRGSLEAWEVLQVEATWSKSIYSYGMAVGLLELADALERGELESEPKSNITNEKARTPAKMREEATKLMEKVPGIRQKIAGKSIPLEKFVARKARKYISQDRRLALPMLELAYLALAIAHAPMNVVETSMIPEVNRTLAELDKCRDNHRNYYSGKGYWDDYCLAKLLEGVCKRYVAYPDPDAELDPAQLPNIPRDQAAKEAKAAFHAVLEHGPKIDFDHQLVYQAHYEVGRLLACQDDTAGATKHFDLVLSGKYLEVGPSGRKGKYSLENALHMRTHAALEALHQNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRG3</accession>
    <name>A0ABQ8VRG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD binding domain of 6-phosphogluconate dehydrogenase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_823623</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF81">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="3">
        <location>
            <begin position="12"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="4">
        <location>
            <begin position="190"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="321" mass="33926" checksum="E8171E2B86CFB09F" modified="2025-10-08" version="1">MSKPTNVFPQRFGWVGLGAMGFPMASQLLQKLPPSCELFVYDINSVVLQKFIQANADHPAITIVSSPKEAAEYSDCFISIVPEGSHVKDVYMAPQRGALAANTGGKILIDCSTIDPGTSLEVGRAVTASHPTNPPRFFDAPVSGGTRGAEKGILTFMVGAAEDDPQFPLLRRIFSCMGTSIYPVGGQSLGLAAKLSNNYLSGMIALATSEAMNLGMRLGIDPKVLSECFKTSSGGSWVNSTVNPVPGVCPDAVTSKGYEGGFKIQLMKKDISLAIQAAKTVDAKLVLADAGLGAYAAATDDPNCRDRDSRVVYRWLGGIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRK1</accession>
    <name>A0ABQ8VRK1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_819820</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="158" mass="16149" checksum="E2571B322FF51ACE" modified="2025-10-08" version="1">MASADHTRDPCPWVILNDFGGAFAMGAVGGGIWYSIKGARNSPRGERFVGAISSMKARAPVTGGNFGIWGGMFSTFDCAIKGIRQKEDAFNAIASGFLTGGCLAARSGPRSALGSAVACGILLGVFEGVGVLLSRVFAEGQRPPLPAPMSPQSSAPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS82</accession>
    <name>A0ABQ8VS82_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_814938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31585" checksum="1752011E4AB848BF" modified="2025-10-08" version="1">MFSWSSQSIVAGSLRNPTSSKTIKRCYAISLTPGKTLPGKKYPRVFHDKKLFQYNWYTRILNTTSRAPLIILHRDDFSANRLKKLRRDIQVASQKFLKKAQEAGEVIEAPTLTVVRSSIFGAALREFPNMRLEDVEKMIGGLPGGYAVLSLPVLDPSLLNAVLRAMDRSVPSRPEKTAEEIAKELAEKSADPAQPGRRMKRQRAVLVPDLKVMGALVEGKVLLPDRMQEVSKLPSLDTLRAQIVGLLTAPSAQLAAVLSQASGGQLARTLEGFKKALEVEEAPEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS86</accession>
    <name>A0ABQ8VS86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_754895</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of an histone acetyltransferase complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The PHD-type zinc finger mediates the binding to H3K4me3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ING family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16859">
        <property type="entry name" value="ING_ING4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059153">
        <property type="entry name" value="NSD_PHD-1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF42">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23011">
        <property type="entry name" value="PHD-1st_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="327"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="159"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="407" mass="44520" checksum="9B171A38529E166A" modified="2025-10-08" version="1">MSPARDSMVGLANHSTVYTLSLLSEYSHTLDSLPLDLSRNFADLRELDAVLSSSMASITQKITMLTQMIEEGTGKKEERLWLLTEIAEEAARLRPGGEDKIRVACQAADNLRNHANHLKALAENIPDFNPSTLNRHTTYPHVAAKSFMPLTAFETTRRRRGGFGSLLTSATDPSPAKRKRLVKDDEPTPRKDKPNDSRNRNRARARKVERQPSPVESLLSVASHQNGTLSRNNSSTNNKRSRSSVQHRAGSPSRDDHFTNGDQRQPSSNGRRDFDVPPDWAPSHNQLEGPGMPVARPVHSGTSASISAVEHMVDLNDGDVDGDGEDKPYCICQRGSFGEMIACDEPTCEFEWFHLNCIGLTVAPEGAWICDSCTSNQVAKKNGRRSARGGKRKGGGNRAGGRAASGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSD2</accession>
    <name>A0ABQ8VSD2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_160525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="315"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="41003" checksum="69849A1065207BC9" modified="2025-10-08" version="1">MNYLDPYDVAGGSNTPPTQNNEQSLNDEVSQVIGQLGRFWGGFKKQSQNALEVARKDLTEVVSQAQKELHKFAGDASNEAQPSSSLSGPQSEELHPRSSSETLKPDAAVSPENASASSSTTSVQNLFSRLQTSLPPNVVSTVQANLPESLKHLSENTDFAQFRTTLTSEFQRLQGVTLTQAEEYVHKSEVLLRDAMKEAGEVLRDAVKVLPPDENTSHNTGLIWDGSDMWMLPSESGDIPTSGKGKGRANSQNAVATRAEALLKRLRSDPNILKHDPEVDGGVYLQWIASDIDSEDGGIDGTHWRAKIDETLQSEDGKTLQATFDILVPSELSQDVFWKRYFFRVHQIQVEENKRKTLLQGISLMPSWSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTN3</accession>
    <name>A0ABQ8VTN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_753663</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="504" mass="56805" checksum="ABCD5540432FDC1C" modified="2025-10-08" version="1">MLTSSLFIWYHRNYHQGSNLPLPPGPKKLPFIGNALDMPPTDQHIKFSQWGEQYNSDILHLRVMGMDYIVLNSWDAVIDLLDKRSGIYSSRYRVAFWEGDLGLMCYGKLFNEHKKLFHQEFHPSNSSLHRPHEKKALGVFLNSLIDTPKEWESNIKQMIGAIIIGVAYGVQVQPKNDPNIDAAARMYGVLNTVLLPGAFLVDTLPILQYIPSWFPGASFKRKARAWYGVRKETVLPPYMQVKQAMINGTANDSFTLRCLTNGENMVDPRVDHLSEEEEMIMQTAGTLYEAGADTGKTALRTFILAMTCFPKAQRDAQGEIDCVIGQERLPDYEDIVDDSNASVSLPYVRAVVLECFRWQTVVPLAVPHLVDTEDTYRGLHIPKGATILPNVWAILRDEKRYGPTAHTFDPERWLLENDNSATGGFGFGRRACPGKHMALSTFQINVVSLLHSFDITPPVDVAGNLVMPEIEYVTRLTSAPAPFECTIKPRSEKHVALIQEMLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTV5</accession>
    <name>A0ABQ8VTV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_608983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="53908" checksum="A9033AF6B5E6817B" modified="2025-10-08" version="1">MHFSIPFLTRSKNLTVTDQSEDSGVSIDDDARTMDELLENDDNVFEELPVETRRRLLRWKLAVYFFTGVIFILLVTLVVIGIQPHSGKELEEPGDDEPVWDDDSEQIADDPRLEKYQTPSDATFCAPWLLTTAESRSSLNLHTKTSQVSFDFPANSDLIFFISRGHPTKGHLTVTSDRMKRLENIAVNVTAEYDHRGHLEQTKACFSENDTERGVMIWAKDIDSSLLPSFNISIELPWSSFRDFSTDLSGGAYTQSFGDFFDLWSPNGFAVVRLKGCNEPIRSLGMFAESAFIQTSDAAVSANFYSSDAVHIRTTNAPIDGVVWAFGQKDEAITEVSMKTNNGHIQAALTMASDFNAVKLNASLHTTNGVLNVTMPRMPFLDPDYNFIVDASTTNAASSVFLSPDFAGTFDLRTSHNSKTQVRWDSGMRDPWGKGRRHKLDMAHYEDVHKSGKVYWGDEVPETMGDIRVKTTEENVWLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU56</accession>
    <name>A0ABQ8VU56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RIC1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_978525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040096">
        <property type="entry name" value="Ric1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009771">
        <property type="entry name" value="RIC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746:SF10">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746">
        <property type="entry name" value="RAB6A-GEF COMPLEX PARTNER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25440">
        <property type="entry name" value="Beta-prop_RIC1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07064">
        <property type="entry name" value="RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIC1 C-terminal alpha solenoid region" evidence="4">
        <location>
            <begin position="823"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="999" mass="112080" checksum="F6C39984DC30B7DF" modified="2025-10-08" version="1">MYFPTSTARRLSIVPALPNIPPENVLTICPSPRKSLFCTLTRNGISIWRVRPSANLAFLSRTPISIIDHGENKEAFWSPDGSRIVIKTSDSYLVLVTVIFHPNETIYQAPPLSTNAQRNFLAGPGEAFPLSSVSLQFEGVIRVEGTLISVSPRKQSVMFSTQSPPAIQRIPWPASEEVVGERGSDEEEYGTRRRKLDNYDQWIINDGDFGWLVEPEVTISQILHDRNTGVESWIASDGRAYIVYLIRNDEPSELPSDSKNASNINLSENDQLQTQKLDHPRFADGSRNVWMGTCIHDFETPRWVQKQRRVEPEEHGSVYFEPRRAVRTAINAKFSLIAVGMLGGGIQYTTFPADEGAVPTSQQIEIHNPFNRRTGPVCSMEWSSDGYVLAVGWQHGWGLFSVGGRCLVSGFGVEDVDEQKFQDTFMNGVVDLFWAPGNFELIVLAQPSLKSIDEQLFVIPFAKSATTGQHSPDNTRYAFLQLEDRALVYRGADQPDISIINPESDVWQHIKVPQGYLAANWPIRYSSLSSDGRLIAIAGRRGLVHYSASSGRWKLFTDPVQEQAFSVQGGLLWFHHVLVAAVEVSKTHQIRLYSRDLELSNQNVLHREVMPSPVIILSLVDNSLLVYCADNTLFHFLIIPTADTIKLHLCGSITFNGVIATPSAVRMLSWMIPSAQKQLGDPVNDLAVATVLMVVGGQLVLLRPRKSAKQEVKYDMQIFAERIEFCWIHLRGIAALENSLWAFDGRGIRVWLNALAIEAPATQDQNENPESVKESVNIPLEFYPLSVLMDKGIIIGAEHEVAARSNLPFVMFRHATSSHLFLHHILRSHLEASQVKDAVVFASHYQDLVYFAHALEILLHDVVEHETDLESDSGSNSQEVLPKVVEFLDYFDAALDVVVGCARKTEMTRWRRLFDVVGNPKTLFETCLQSHRLKTAGSYLLVLHNLEQLDEKNVDAIRLLKSAMEEKDWQLCRELLRFLRSIDDSGVALRDALAQTGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU81</accession>
    <name>A0ABQ8VU81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_812665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006328">
        <property type="entry name" value="2-HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01428">
        <property type="entry name" value="HAD_type_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF3">
        <property type="entry name" value="HALOACID DEHALOGENASE, TYPE II (AFU_ORTHOLOGUE AFUA_2G07750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="29517" checksum="DA82494EC63EE1C7" modified="2025-10-08" version="1">MSAPPSPNPLHGVEVLLFDVFGTVVDWRSSVTKELENLGKRYSLNDSPQDWLAFANEWRKGYMENTRRIAEGGEGTNDVDVMHREILDSMLSSPRWSHIGEALTEEKARVELNLVWHRLDAWPDTLPGLHALKKHLIIATLSNGNVRLLVDMAKHAGLPWDAVFSSALWGVYKPNPLAYASALHHLSIVPNKEGTTKAAMVAAHLFDLRAAKKAGMRTVYVRRPGEDAGLSDEDRKRLSGLGGGDVDGVDVVVSDFMELARLFGDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU91</accession>
    <name>A0ABQ8VU91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_977859</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="235"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="280"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="280"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="361"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="361"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="335"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="484"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="664"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="484"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="696"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="738"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="754"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="786" mass="86196" checksum="2D4A26B19032315C" modified="2025-10-08" version="1">MLSASSTRQQIFTAVQSNTKHQYALEKYSQRLTAELQEIDKLLAAADVGDSDNEQPGDVEIQGASRATGPIPDHEFLNPVSPFFSEAIKRSRYCKSTVTHAMRPKELGTLTDAVTAEFRRLRILEGQGSASSAIDLTSNTDRLNWKTIAEKVSDASYSLRSDRECKTKWVGYQRPGICHDDWTLDELKKLKEIVADKEKDEEYELDWVDVALELGTNRTPIDCMRHGFKRVNHTWAPEADRKLFEAVQVYGTENWALVAIHVSPNVTSVQCQMRYNRSLDPLLNKSPWSSAEDERLNEIVSVLGSSSWPEVARHIPGRTNEMCRERYLERIKAKGQVNKGKAKAEGDDGNSAQETEGDEPREAIARSEWTKEEDEELVRMVGEMGNKWQKISAATGGVHTNVQCRIRYKKLKNGTLSTDTNRSSHSASITNDQPSRTSAPPPPDLSPNAYLSLAPSGSRHALTFITSDSHPPILQLAPTSIAQSSTSPNVSVAQPSKSSLALAKPRPKPKSKAKTNVPPQSMTSHTNTTHNSHDNEQQPFSSNSAVITSSVISSTTTVPPRPARKRPSHRRAVVLSTAITENLETLEPTRGVTSVLSQAQIRGWEAEGHSSIESQVTGWGAEKGREADGLVQGWEGEGRVREWEGNTNPALKIITGAAAEVMSDIEGPDPSERAGSHSFATGSPLSRKRQRDESSDTMSLSASKNTVSVQDKNSSEAGVESTTNIEHAIGNTSTPQRRPARKKERSRKRTADWSVVPVSPTTSSLPSTPASGSSTLRRSTRLAGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV26</accession>
    <name>A0ABQ8VV26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Linoleoyl phosphatidylcholine delta-12 acetylenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_960314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="93"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="422" mass="49614" checksum="958364D40D615433" modified="2025-10-08" version="1">MSEATKPQAKDLYNEADLPQFEPMPWSLKEIRDALPARLFKRDTALGLRYLAVDLIMTTALWTAATYIDPYFGKAEVIEKFSPIGAEVARWASWSVYWWFQGLVFTGIWVIGHECGHGAFSENQWVNDIIGFVTHTFLWTPFFSWRISHHRHHSNHASMERDEVYVPKTRSDLGIPPEKAEWEPLDWDELFGDTPIYTLYMLVRQQFLAFPAYLLWNVSGQKHYPKWTNHFDPNSVLFTKSQRGIVMISNAGIAFMIWGVWKSCQIWGAADTFKYYGLPWFLVTHWFIMITYLHHTDPVMPHYRGKEWNFQRGAAATVDRPFLGWQGRFFLHDVAHFHVIHHFFPKMPFYHGPEATDYLKAFIGEHYNYSDKPVFKALWENYNDCQFVEDEGDVVFYRDKEGKSVRRPADAYYLGKKSTKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV53</accession>
    <name>A0ABQ8VV53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_893009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF263">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BUB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="49"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="306" mass="34848" checksum="0E60724B8CA1F5CE" modified="2025-10-08" version="1">MSATTAHSFNKILSKPKYSSKSRSSGVDDDDSNLKKLRRMILVEGIPSSVDPTLRPRIWKILLRVNDISASSYLQYVSRGPCEVREKIRNDTFRTLATDRGFKERVREDMLVRLLDAFVWRNHDTQDTDQLGFTYVQGMNVLAAPFLYTMPSELEAFSCFSKFIEESCPLYVQPTLEGVHRGLRLLDKCLKIVDPELYAHLRSKNLSAEIYAFPSILTLCACTPPLDQVLQLWDFLLAFGVHLNVLCVIAQLLLIRDEVMSSSSPMRLLRTFPPLEALPVIGIAVTLVRDLPPELYDELVKHPYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVF2</accession>
    <name>A0ABQ8VVF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_914422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="158" mass="18409" checksum="C92FDEFE7DBC3C0E" modified="2025-10-08" version="1">MSRIWREREYFQHVITGLSMKPLHLNLGGFNGGIYKLSALDSEFEDENRAGPGHVIKLVDLHQEYADFHPNNVHVVLKLENKRITVVGVRLLDFGYPGVHTTTELPPEKKFRAWFDLRFDLLWNYVYELLGEKPPHYMKYVALIEGEILEVDDPSVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVH2</accession>
    <name>A0ABQ8VVH2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_814463</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the RRP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 9" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="98"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="313"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="41567" checksum="99F21B1202C1E80E" modified="2025-10-08" version="1">MPIRPFISTIRKGNERRSSRQTEEEQKDRWMNETSSEPEDEDEVDDDAPRVAQWVDEDILDEDATEAEYSQAPKNNLTLLETDLSSLPMGTLRRAQKILQVKDISDASDIERESSEDSNEENAASKPEWGTKPRTDINKRKDKHAPMEITSKKPVTRRRTVVNAQTPQIRDPRFLPMTGEFSSQKFNDNYHFLNESHKTELSTLRENLKRARKFLVTSPRDTRHEREVEIERLELALKKAESTVNKDRRDAVEHEALRAARREERKKQESGKGEWYMKKNEKRELLVRARYDSIAEQGGQRAVKKVIEKKRKKIEQKEKKTRPFEKGGFAQGVSSKRSFDDVYNRNREKRRKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVK7</accession>
    <name>A0ABQ8VVK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_899888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="196"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="274" mass="30447" checksum="96ACADCD670B184C" modified="2025-10-08" version="1">MGYSFDDLEPLVRQILSAPGTDLTTISAKRVRRELLSLDPSLTPEFVKANKLDVDAVITRVFGEVSAAQNGEVIDAPQEPVTASRRYSSSDQEEAEQEEEDEDEDEDEHMPKKSRKGPKKELSDAELARQLSSEINGRSSTRRSTGKGRAANGTPKKSRSKKKSATTIDSDDEDTGEEGGKKMKKKRAGGGAAKGGFAKEYTLSAPLAALLQVDKLSRPQVVKQLWVYIKENERQNPDNRREILCDQNLRAIFNVDKIDMFKMNKVLGSHLHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWB2</accession>
    <name>A0ABQ8VWB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_347094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="685"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="929"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1267"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1419"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1293"/>
            <end position="1307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1465" mass="155419" checksum="D8D7C05A09C67490" modified="2025-10-08" version="1">MIPDRGSGEAAGISHVNVLAVSTPSEETPNSVTPVLTDPIIGGEEFTVGNIVTDGSSGEVQVHLTEGIESEKHRLLDSNVREHDLASPAEPAESHSNELDSSAAILVGEKPGADANIVLGYPKNLESNAEGSHAIPLEALTIVSAAALQHSVSPPLVEPTQIETGQLSSTLENSEDIPTGQAPAGNVHDESSLEEMPMNFSETLEPLVERSTGNAAIETESPSELEHESELIATDEVAGTDGQSKLEIVPALEESSVTPDKISETAYDESEAKLVTESDVLGVILATGNVNTVSADPNAETTLPISGEKASSVELEKQLAGNVEAPNEVILNDGEKPAANNESTNTSSVEDVPVTRDEAVGPLVEGLTSNEYPANKDELSEPESVLDTAQSDVKPDEEGLDIGFDNNLDVANTVVDSAASATQSLETETEQHLMEETGGIVVTNEDADVEVAPASGEVGGEGAQVFPVLVEEQSPSDTTVERTIADDEALLKEESIADLAQDEPVDLFRENSGALVEESLNADPATSLIGSVVKDHSTDTIVQFLSSGEAISDASINQFTEMEQRPVLEPQIQVNQRAEVPQDEAADDSEAPTNEVVPPAAPEAPFAEDIVPPIMVTVDSQDEISSHTLGLEKPSLDQEIQLTELTTSSESAQIDVEKLVEVMPDTPSVETAPEDSSDLRVHVTEVERPESPWTSSYSVSDQGPDVTREEDISEIEQLPVSDVVTSAESSVPMVNIVLEESEPTANIVPEEFEPTDANPEERKEPSRPSSPWVPSYSVSVQGSPSISAQGLDFPNKESPAHPAESSVDELIPGTEELPELDIEIAPSVYQDEPEDNTAIPSAGLDQLPEVPFGVHLEITENPQEPVSISDEEVPVGVSVADSSLQGRLDIEDAPATVAIENREGEHENEDTTEPADVVNAVGAEEIRSEIGAEDSMNLSINTTEIDRPKSPWTPSYSVINQGPDMAREEDIPEIQQLPPSSVPAGQELPVPEVNIIPEVSEATVANPEEPKESSRPSSPWVPSYSVSVQGSPSVSAHSSPVLAATELPENVIPVIELSEESVSAEGSALNDAAGSIEEPSLEVDPLPSELPVDSVIHEENSVIPSVNITEPSSEISLDIPRESTEADIAQTPMQDQTVNMVSSVEEPLVVDEMLDQSGNEDTAVFEVPDEEAIVDLSAKPYKDVEIPEALSLSHSVVAAQIERPKSPWGSYEVTNQSRHETSIADIADPEVVETVENIPAPTSFIRDEPVLEPADEPALKDICTTEDAPAAEVSKLTVDTTENDLPERPKSPWTPSYSVSRQGSQVFNEARNDAELDTLKQPPPHGESSANAPITLEEPSVSDVIGESVSTPSGETFPALSVSGDTDRDTIGDTLAAPKDRKRLESTTSSLFFPGGWFSKPPTGRTSLDNAQGVITSPKAISPVEGRPSVELLGGSFAPGSATADITNEGPDEDNEKKGKWCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXA1</accession>
    <name>A0ABQ8VXA1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Las1-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_755456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007174">
        <property type="entry name" value="Las1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002:SF0">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04031">
        <property type="entry name" value="Las1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="477" mass="52139" checksum="2820E75BBC1AE2A9" modified="2025-10-08" version="1">MKLPRRVPWASVGELDEVCAAIYADESNLESKIFAVNKLVAWKAITSLPHAIESTLSLLSVIVQDDCSNASSLVLRHSYSAAVIRMVNGLVDPLQFGIYARSIAAIAVQLGLPAWLVELRHAATHEDLPSLEVLREAARQSMTWLLHNYWLPTLDPSTASQPEAPPLQPLEPILKEYRSLLKLTTRDASLNKQYKQAMTDVFKNIEKWIAEATVAANVVNGGLGWDQPDGAESSRDAREQWALEVFSDVLIGKGGLVPLSKKKRVFPPESFCPPENSVQIWTPLLMSVQALHPECLSTLVNRALSRLLATSTTPLENDAPPDPSYDSTLARWILWLVDRCDLDQSSDGNTRADIVASLLTVLGPGSKHLAHAKKKYLGSLKTSCSNADIFYSLNELLSALCTGYPSLSSACTDWTAKDLSVMEDRLSVLVSLTAENEDQTSNVFNETGAVSSAGWNLLDSSCWKPCPIGVACAPIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXD8</accession>
    <name>A0ABQ8VXD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_899313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="161"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="284" mass="29748" checksum="A1DDD51A2F8F2390" modified="2025-10-08" version="1">MEAAQQSPLSDAPFCQTSLIRIGEAGQVAGSTVLNGERASTAGSRGANGRRRRRSRRGGAQQGAEAQGRARGTGGTGRGNVIGGAGDSSESDDGNIGTGPGRGTRGTGRIAGRGEGRIRGTSGGRGGRGSDRGRGGEKVVGAEEKGVQVVESEEVKGEVAAAAAEEVEVEVEAEVEAIEEVEAMEEVEAMEEAEAMAEVMEEAEEAEEAEEELMVQEEEVEVEVVIEDLDDEGKDKDKVELDRPGVFGVTLSGRTIYDWEVGGEFADYYDPGLGFTPSDYDRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXS8</accession>
    <name>A0ABQ8VXS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_810959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12796" checksum="B472DCEB8A366AF3" modified="2025-10-08" version="1">MIISYLLVTSLSCWSQLHFLTYSQTIIYLLYVSITKVTVNFQRSVVFPQLSIQNDSEESGKACVTVYICTRKRPSDLPSPDRVDALLNIAFFAKHLHSLAHHHSRPSPSSDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYY8</accession>
    <name>A0ABQ8VYY8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="8">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_927951</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08382">
        <property type="entry name" value="C2_Smurf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024928">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001569">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 8 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="C2" evidence="11">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="12">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="12">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="12">
        <location>
            <begin position="443"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="13">
        <location>
            <begin position="532"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="169"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="169"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4501592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="865" mass="96694" checksum="A04328FEDFECDFE1" modified="2025-10-08" version="1">MSNPSGVLTKNIRVTVVAADGLSKRDVFRLPDPFAVITVDAEQTHTTSVMKKTLNPYWNESFDILDSLICSTVKDSSVLAVQIFDQRKFKRKDQGFLGVVNVRVSDVLDLELGGHEMLTLDLKKSNDNLVVHGKLIIYLSTNVTQPIPNPGPSQVNGLSSALADMGLNNANSPGASTSNLVLPTNPSGTLSRTTSSHATATDNTASPAVVAPSSAPSTETEQPSPQIVAVPSSSRPTSISGTNPSANNAAPANPMNPSATASGNANQMRNFNPNVDQYGRLPPGWERRIDPLGRTYYVDHNTRTTTWNRPSDSAAVNNDVQDSETNAARDQHSRRILADDLLEANNSNNSTSNVFRNSTATVNATANPAPAALTTGSNATTAGSGSLPNGWEERFTLEGRPYYVDHNTRTTTWVDPRRQAIIRVMGPNGQGSSLQPQAISQLGPLPSGWEMRLTSTARVYFVDHNTKTTTWDDPRLPSTLDANVPQYKRDFRRKLIYFRSQPAMRAQPGNCQIKIRRNHIFEDSYAEIMRQTPNDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPASGVNPEHLNYFKFIGRCLGLGIFHRRFLDAYFIVSFYKMILKKKVTLADLESVDTELHRGMTWMLENDITDIIDTSFTTTEERFGEMVTIELKPGGEDIPVTEDNKKDYVECIVDYRISKRVKEQFDAFMSGFSELIPQDLITVFDERELELLIGGMSEIDVDDWLKFTDYRGYEMTDEVIQWFWKCVRSWPPERKSRLLQFATGTSRIPVNGFKDLQGSDGPRRFTIEKSGDPSQLPKSHTCFNRIDLPPYKDYASLEHKLTLAVEETVGFGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYZ9</accession>
    <name>A0ABQ8VYZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_4772</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="24822" checksum="A21C74883FA78ECA" modified="2025-10-08" version="1">MSIAQNFVKHGKKILAIGRNYDAHIKELGNPPNAEPWFFLKPTTSYLRNGGTVLIPEGVQMHHEIELGVVIGKDGKDIKREDWEQYVAGYALGIDMTARNFQQLVKAKSLPWTSAKGFDTFCPISDFIPKENIKDPMNLVLWIKINGEERQRGNTAEMIYDIPELIRHCSSALGLIVHGDKISAGLERLEGEVLATWDGNAADRVGGYVFNQNAYVAGQARAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0J9</accession>
    <name>A0ABQ8W0J9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="77"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="430" mass="50355" checksum="BBE6379D3959E231" modified="2025-10-08" version="1">MPGTLRRKHRQELTLRRSLMEVMQAKLSISVFRRPSDQHSPRPPDNRRRDPCAEHRFKALPPAHRSSATSYTSTHSIRNLPPELLAYIFVLGCEDDPMLPLSVSHVCSFWRALALNTPVLWRRVVLGSHYNMWEETMYRARDCTLDIEFKPQNHRGPLAFYEVQQYMHLVMPHITRWRSLSIVFSEYQPYLWNNALSECCTKSNYTQVPGLEELCLVYRHNDDTKEFCLFSGSAPKLRRVTLDGIRLTWLPSLFQNLTYLDYTHHGKSNGYHAIQEIGNVLRVSSRLIELRLLFPNQGHITRAQNTQTSLPFGSLYLPWLRALHLRVETRQIPEELVLLASIFTTPRLSELLLIDTVGQRLAFRHIDAFWSAYTIPFSLRTLHLQNGWYTEDSVVFLSRVENLRWLVLRRGCSDVVHWLNPDIQRSPERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0X8</accession>
    <name>A0ABQ8W0X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_748558</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="84"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="531" mass="57814" checksum="B35FB08E17807A1A" modified="2025-10-08" version="1">MTSADCSSVFHGDCTSIVVHDRNSQSHTCKESCPVEEKTETDGGSSGHARYIGSGMHEDPYIVVWDEEDPENPYNWSKTRKWIITMQLALTTFTVSFSSSSYSGGLEYIVRDLNVSDELAVLGISLYVLGFAVGPLLFAPMGEMYGRRIVFLITVGLYTPLHIGGAFARNITTVLIVRLLSGIFGASPLTNAGGAVADIFNPRERGLASAIYAAVPFLGPVIGPIVGGFVADSSLGWHFNFWLMLLLGAISLIMGYFLAPETYAPVLLRRRAKHLMQLSNGTISYKSKYDIGRSTSFMKIMRVNLSRPFVFMLTEPIVLLFAIYISVVYGTLYALFSAFPIVFETRRGWSAGVGGLAFLGVGAGISVGTATASIQNTIYQKAMDNSSTGRAPPEARLHMAMMGGILVPIGLFWFAWTADPPVHWIVPIIAGFPFGQGVCQILQSSTAYLMDAYEIYFASAIAATIVLRSIFAAVFPVIAPTMFENLGDAWGMSIFAFLGLACTPIPFLFWKHGKAIRSKSKYAFKESDDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W123</accession>
    <name>A0ABQ8W123_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Ribosome biogenesis protein NOP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_9328</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NOP53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011687">
        <property type="entry name" value="Nop53/GLTSCR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211">
        <property type="entry name" value="GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211:SF7">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07767">
        <property type="entry name" value="Nop53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017302">
        <property type="entry name" value="Gltscr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="275"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="437" mass="49025" checksum="DB21639452379E17" modified="2025-10-08" version="1">MSKSTVTGAPRTKKSLQPSRKGKKAWRKNVNLKDLEEGLEERRGEERLFGGALSEKPDLDLFQIDKEGDENLRSILPKPKPSQLTSLKILSERSAVPAVFSRTTGDANRKHHLSREEKDRLLKVAKRQRKGPFGAIVDDRDGWSSGAAASGGVSEAVKSAGHYDPWATSPPLLPKSIPLPIANLPPSHAPLQTSEISTNPRSLISLPAVPLPHAGTSYNPPVQAHMELLHRAHDQEEVRLREDIRWKEIGQAIKDGVTTQPDLVSVVEEMVSHNLEEDVDREEKEEETLPPRKIPQRKTKAERRKATKLLVQKRILAERAAKRRQLSYLAELSAKHSRRTGNSLASQELIQQRKKASQEKLKAGIVGHKIGKHRVPETLVDVQLGDELSESLRGIKVEGNLFKDRFLNLQQRALIEPRLRVLYVYFGTFLLIQTIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DDA3</accession>
    <name>A0A9W9DDA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">UbiA prenyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8J55DRAFT_566733</name>
        <name evidence="12" type="ORF">C8R41DRAFT_913090</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000057">
        <property type="protein sequence ID" value="KAJ4464633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DDA3"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000008">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040876706" evidence="10">
        <location>
            <begin position="25"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4464633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="270" mass="29742" checksum="E7949BF8E2E06E7C" modified="2023-11-08" version="1">MSAYKTNMPLSALITRLVVYGVGSLTLRSAACVWNDICDVDFDRQVERTKVRPLASGAVSMAGAYTYLISLTLAFVATLYMLESKEAFYQGVFDVAVLNLIYPLMKRVTYLPQAWLGLAINWGFVVAWVDVSGRSVTSWHDFEVLAYGMVSLASWTIVYDTIYACQDLNDDKRAGVKSTALLFGSYLPAILRLFAAIYIGSLAYIGYLNGQGAWFYGVSVIGSAVHMLWQLGTHNPMNAANCKERFDSNINLGGIVTSGLLVDYLVRVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DYH8</accession>
    <name>A0A9W9DYH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_392579</name>
        <name evidence="9" type="ORF">C8R41DRAFT_739031</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000007">
        <property type="protein sequence ID" value="KAJ4489715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DYH8"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="57" mass="6753" checksum="07B19DE72846BCAD" modified="2023-11-08" version="1" fragment="single">EDKRRRNTAASARFRIKKKQRNLNLERTVSDLTGRADELEKEAADLRRENGWLKEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWA8</accession>
    <name>A0ABQ8UWA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_927273</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000154">
        <property type="protein sequence ID" value="KAJ4463718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF342">
        <property type="entry name" value="OUTWARD-RECTIFIER POTASSIUM CHANNEL TOK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="10">
        <location>
            <begin position="243"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="10">
        <location>
            <begin position="385"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="515"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="616"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="635"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4463718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="697" mass="77600" checksum="BD416D5E1E7CB89B" modified="2025-10-08" version="1">MNDPGLEDKIQDTATHVTQDLRDRAGSNSSRKPQTEYAHPKSAGDAFREELQVDDEEEEIGYFAPQRWWFTSTAFPLVAGTFGPLANLFSVCALVQTWRVKISGGESETQGQQISDPHWLIGLNAASLILALLANVLLLFNFAHRVRYIIAQPLTISLWYLSSLLLIIPLALTPSITPPSNVSQHALSQSYYYALLSAILYGILSTLLLLHLIFSLKPFSAYPASFATLTIPQRTLMLQTISFTLYLALGAGIFSALEGWEFCDGVYWADYTLLTIGLGSDFPLQTSAGRGVLIPYTGGGILLIGIVIGSVRGLVLERGGVKMLHRQLAKERDRGIKKVKKRLGMETRGDSDEALKAEFDVMRQVLRRTEISRKYSSLGISFLVFLVVWFLGAMVFFFSEADSQNWKYGTSLYFTYTTLLTIGYGDLYPESNSGKPFFVLWTLIAVPSVTILISNMGDTVVAWVQKGTMWLGQRTILPERSLRSDKDTRINSTDSRRTRIRTRLRQKGFWPLKSPESVEKAVHSEEAREVDEGAVPDPSRTQANGGGKNQEIRGDIEKLGDAVETVEAERGQGGGIAARLAREIKLVSQDLGKQPPKEYEWEDWKRWMRLLSVSNEDDGRNGRSGLGGLKSLKSPTRSMGTRSPSHSDASRSNGWIWLGDDGPLFSQESEAEWILGKLCDRLEQVLMNEVLNARTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX48</accession>
    <name>A0ABQ8UX48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_839556</name>
        <name evidence="2" type="ORF">C8R41DRAFT_860618</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000148">
        <property type="protein sequence ID" value="KAJ4464043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="151" mass="15936" checksum="79E33310190B35DD" modified="2025-10-08" version="1">MVQTVPMSTMLPVQPTVQSVGPALAEEIPTMDLPALTKTVTPTMKDPETPTIANSASLTPPIPLASTVPASGPGPSTSRKPKIFAAPYKPSKSSKTARGLCAIDYMAKTPNKNASKVQFDAYWGSVRETDIGKMYQTRANAAGNAMKKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXG0</accession>
    <name>A0ABQ8UXG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_113533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000134">
        <property type="protein sequence ID" value="KAJ4464819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="270" mass="30325" checksum="B76B1AB91D4C9321" modified="2025-10-08" version="1">MFSLGNKNKKKGYKYALAPPTSQKKVFSVPDSSDVLQEVEGESDVPNGPLPSSTTIFTSAPENLLARHARVIPPSELQSLGKLPKNMFVTSVDVEEDLWNNSFSKKKKKKKHWEEDYTDTVREKPRDDEIQSTLDYGLAEEDPTFSNSETALAVNDLDAEDSKSMLIWSVVEQNFKAFPQVSLNSLQNGKLVAWKALALNLETYSPEVLLHIATVTAISNDSSGGNSSFSIRRLIRPGWEELDVENIQGDYTWENVEQMGWRAVNEIQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXM7</accession>
    <name>A0ABQ8UXM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_927614</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000186">
        <property type="protein sequence ID" value="KAJ4463254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4463254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="42187" checksum="72EF1C1EF423119B" modified="2025-10-08" version="1">MTSTPVPNTFSSPQNLFTSSNNALDQTDTVSELGIFLDSHLSPSVAKELIVTARALVGPRGRGIYATDESPETMDALFRAAERDIEEQGLKVYSDSEKSERRKEWKKDAYEVLSSEYISGVILSFETLLEFNLGQILTEKDIIVGVRAHGELAPLPASPFEFIVQGLDNLLPQLQAARAAGARFSKWRAPIACTSPALELPSQVSLDIQAETLAMFAAISQEAGLVPIIEPDVEFSADASLERSVEIHEKAIGMIYARCREHGVLLEGTLIKPSFPQPGLKHHSRSTITPKDIAIATLAVISRSVPAAVAGVVFLSGGLPSSVAISYLSAVNALVNSSSAPSPFSRLLPLTFSYGRAIQGDAIKLWVRGEKDSMKANLEEACQGCYKAAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYW0</accession>
    <name>A0ABQ8UYW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_74983</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000116">
        <property type="protein sequence ID" value="KAJ4466328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="899"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="981"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="159"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="229"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="440"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="579"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="674"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="833"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="940"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="263"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="443"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="581"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="604"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="621"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="684"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="695"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="706"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="748"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="837"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="850"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="950"/>
            <end position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4466328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1111" mass="117655" checksum="D5AD7E11F4095139" modified="2025-10-08" version="1">MAPILNLKFKGNKSFVAFSNLSDVDALTRTWKVCTKVASYLEQGQRLENLSWRLWHLQNLMVDTDNAKSKREFKKLSKNMGDRLDREKGRNISELSAPDFKHSHSTDLIRQKAVERERSREEAAQEDAAAVANGLGVNGVGGPGTRTIKRMQFTFSVNEDQHSASSSTGFQPANGTGSYHNSDSGSAGYTAQPMHVDKPDLKPSAEFSVGKRARGIGFGAGIASAKHSTNAASSVSSTSTNAGTFTAKPNDHAHDQMDVSGDAQLTLTQRGRKTSSTSPSNAPRNNTFTNTRDAGTLSTTIRFPPLFSSDFGPAALLYPSPTLTTHLNYGEDLGLSYPHSYDSNDQNNLHSNSNSNSQVNNGASHSDDTYSAFSIPRPTIELPLDELLRGMDGFDGMDGMEGLDGGDDMDSLLNQFAPGAAGGERSWRPWSPAFFATLSQKGSSGATTNATDTSTRSSNTTQTTTATSSSTPPLFSTTSLVPPSKNNKADDFYGEDENQDVEMFDHSSSAYDRSNLLYDDNPNNEHVSAFDYDHNSTEPIQIPITTVSGNSLHALFGESPGGRSDGRLLTPFEETLSFSGQHDHLSRHNSHTDSSSHRTHLSNYEDDAESSVDVDVESDNSDSGSDSSESVELMSSTTMTTLSSAQRSTEFVYSGVGSIGGVKKKLSGIKLTLNHNKSKSLSQRRSTTPRPSSSTGGGRVAGGGLSVSSRPSASSRPYNRPTPRANARAAPRPSARPTPRAGVRNSHNSNNTTPRSSAAASRAASSRPALTVRTSSSGVSTRSSLPSATAPPSSLVSSISSSFSASGSGSGSGSGSVGFGFLESAPVSAFKVEDEGQGQNSHAGNNVNNSSSSSSTSTPPASMTTAAAVAPAPSLPLPSTTPRTTPPTTTTTSTPGAPAGQKAECSNCGATHTPLWRRGLNDELNCNACGLYCKLHKRPRPKTMRNQHGGESGRGAGAGGGGGFGSGLGGGGRETVEVMAQCYNCHTTATPLWRKDDEGKTVCNACGLYYKLHGSARPISMKSDVIRKRSRHDAHAPHAAHSAAIPANRRGSLSGGAYGYGGMYSSLFFLFFFSSAEKHQITSLPLLILKTRLLRWEGIMNPRHLFGSLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZB3</accession>
    <name>A0ABQ8UZB3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_780200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4466780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="134" mass="14833" checksum="14A96BEEDBDB4300" modified="2025-10-08" version="1">MSAYSTGGDDITGQNEGESYSQYAKYEGSWPSYPQASGVGETTAPKQGRPPARGRYANNTEVRVVSGGIKKATGDRRYVCTAPECGKCFVRGEHLKRHVRSLHSWEKPHKCLHPGCNKSFSRRDNLGQHARVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZE2</accession>
    <name>A0ABQ8UZE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="434" mass="46787" checksum="9A856081BFF78405" modified="2025-10-08" version="1">MVERFLHLDTSLGSPTTRTRSVFFILFLGLFTVNLNANAILPGQSKLIGYNTLTLERRDGENATCGPDYNWANNDAGISPCVMAAAIEACETGPHTLPPLSMGSHYNPPSLETNSVNVCQCSWASYNLISMCTVCQGQAASLSPWASYIVECNGFTESNSYFPLNYEALLPSNNSIPLYAQTNPLTQWTNGVFNVTQAQAVVNGTLSLQTSTTSQSSSSKPIAAIIGASVGGIVVLLCFTGILFWVRRRHAFKDEGRYQNLPTVGTPSGIRLSSSTPHSTISTRNDGSLRNSLHPSSISDYYTGSLIHSEDSTRNSGVLTPFRKSYIVYPTAHDDGIYARPEDLGLIRRNTGPSVAPRSTQEMYGIIRDHQPGLYSEPVLPGSSNSGPAIYTYEILANNIVEEAEEVPTDSSSPSARRISNPPPYSPGGPAGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZQ6</accession>
    <name>A0ABQ8UZQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_985664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000167">
        <property type="protein sequence ID" value="KAJ4463406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="79"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4463406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="559" mass="60204" checksum="B21B50F3B7031CAB" modified="2025-10-08" version="1">MSISRNDLSASSSSSSSSSPTATAAPIPRNQDLSESTNSGQQSLQADKIAQEPLTDEKTNDQRAQEPYSIYTRNEKWFLVMLIAISGLFSPLTANVYFPAIPAIAGAFHKSTELINLTITMYMIFQGISPMLFGTLADNVGRRIIYASCLLILSLTCVGLALIPTSAYWLLLLLRCLQSTGSASTIALGAGVIGDIAEAHERGGFFGVYQSGPLLAPAIGPVIGGALAGTLGWRSIFWFLCISSGVAFLVVIIFLPETLRSIVGNGSLPTTSSILHQPLIRIVGRGRAGGSSRSKSESNQPQPPSRKRKPFKNPFGILLHNPDITLILFFNGTVNAVYYAVTATISTLFASAYPQLGETEVGLCFLAIGGGMFLGSLTSGKVLDWEFGRIQKEVVKEKGRGKGIERGEGEEQKKTGRYDEDFPIEKARLRLIPFFMIFFVGANLGYGWSIQRKVHISIPLILQFIVGFIAIIVMNADATFVIDLMPEQSSSVSACNNLFRGTSGALLVSVIDLIANALDGPGWTFILLGGVCAVMTPMVYVVMQIGPGWRIRRAIRAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V027</accession>
    <name>A0ABQ8V027_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_906122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF55">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="277" mass="32714" checksum="3E3B8F4CB5734A70" modified="2025-10-08" version="1">MLRSSPFICDRLLWFLDRVENVVRKVWSVTFGRFVFVKILGIGDDTTVEVATMKFVLQHTNIPVPRVFVVLRYRGRHHIFMTRIAGKELSRRQWKAYSQDSRDHILAQLRNYISQLREIVPPPHSPPFICNVLGGPIMDHRLCVDRPYGPYCDEEQMNLQRRQGFSVERFAENFNIPEEFVGLIKHAHDLRHPVVFTHNDIAMRNIMVSGDRVTGLIDWECAGWLPAHWEYVKANWTEFIAEEWIDDLRKFIPPYDLENEADELIGWSRSWEPRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V065</accession>
    <name>A0ABQ8V065_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_927201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="195" mass="21313" checksum="9B34FB46E44B9104" modified="2025-10-08" version="1">MAARRPLLNNLRQRPPTKVSSQYHAFSPSGIENVECLPLPRIADIFDAPTRLDSTNGHQFFFLHRASTAPPTPTMASRSSNAGRSSGGLPAPLMFEGPAHPRSSFSLLSTKPPRTVKSQSRSHQTSHKTSSMLQDSTSIPLSIKNAAVHTYEGPSNMTRYRYKGQKKKNDDGRKPLLAMLSLATLAVGTTVFLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0U3</accession>
    <name>A0ABQ8V0U3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_985544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000148">
        <property type="protein sequence ID" value="KAJ4464055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="34506" checksum="9E3A5DEA62DF4376" modified="2025-10-08" version="1">MTVDITTNSSYSGLLKVITEEQHLNPADILDDLEESHDQVEVDLSGLSDAIREVSKGVSEKTLQEYLRCDIIDLDGKAIATTKERSTYTHAQKMRAAATFGFGRVHGLDMQAWHFSAVTQSGDTPTSARAVTSALLENLYYFNRKPEFREPQLSSPPTRKGQLGPRAHSMMNCGYNFSFCGLLCVDEMLKIQLQDINLSDDPKTGQLKLSLHLPFRKTSQFGDIKPFVWYEMPEEYQHICVVQAFVKWILISGLTEGYLFRKIRANDRLAEENEPMTSEQFLEMFRNNLLDIGVDFVPYGTHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V134</accession>
    <name>A0ABQ8V134_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_632387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="562" mass="62313" checksum="A90C0BE0390BDA85" modified="2025-10-08" version="1">MGPPRIDTVALLLREKDQEILQLKLQLKAYAARTSLIQSRLTSTQDALDALQLSHDEELRAEQAAKHKMQQQLKTYYQFLRSVNYEKEDLRNVIVSFLRRVYMSVVEDPHNTWPQSQLHVSSLLEPADPKLLMRRNQDVSNDFDQRLMNYAAAMIDALVHERDLARTAHQSLLSDTKAQIASLGAELARRDLELEKCISHCVDCPEFQGGTGFEPFTPMEPSVLSKILQKTSTRHKILELGNQQLEGQLENLRQNISVPLASTSQIKCSDRIQHEETSREIQDDSDPVCMSPKNGDVAPSLGNVNPTSKLIAQMDTDIRNLGLTINAFASERDRLQKMVTEQAVIQKSVSAPAGSEIESRRSVHLFQDNASVDQRDMEVAYAASLCREKSLIEDNLKLVGRLRDLHSSEVPDSDTKAKEDLRPLTRSASSAPPQLIDAEDGEVSMDLATPLLPTTFIATEKPRRTNTPGTPSTPRPLIPLSPALVSSSLFGQERSPSSPCQGQSSIPSEDMKSVEPLIQPSTEDVGNEIASKLASGEQQVVQSAGVVNRTELVLDSETNLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V193</accession>
    <name>A0ABQ8V193_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="57605" checksum="A1FBF0A057C87559" modified="2025-10-08" version="1">MQAPGATDGYGRVVGSQGHSCVTTASGFPGLTVIQCTNNTRLDHASQSLPQNPKKEKRRGKAIRPPGLGRRERVPSIDDCINVASGGVEVISIDVLVYLPLPPTGEINFYHLPRQLIFYEINKEAYRMVLNALGLFHQYPNLPTSTTIFNLFSDITVKLRQQYNLPSVSSSLPLAPQELLPLQLLGFSNHGWANGSYNTSKLRPMPYERYTTIQDILTSNFGTYVIPKLVITRDNHFTLHAITHLRPIMFRNASDANLNVNALDEEEIEGSCEPDDDDDDEEASDSRVVAQSLTASLETDDEEPQPSSGLEQNSNVSQSPSMLVSTSSIVDPVLPKKLWEEPWTQPAPLSFIPIFFDDERTPTIFKIVSEVQSQGSNCPGFQVKGTDEQELAAKFIAQMKNSVQSGDWSKVLSPTRHFVCVNDQDDYISSGPGLKQSAIAEVFRQFFEERESEFCTPLYEGYTTLQAANVQISSSKHEELVLFGAVTSLALVYGHYPGHVKPMPRASIPPLGILKIYLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1J6</accession>
    <name>A0ABQ8V1J6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="16591" checksum="20584903600363ED" modified="2025-10-08" version="1">MTRRPTYRLQKLYTRQRLRLVSPSDGRGWLYAYLDGGIEWKIGMSKDFVRRRRDWEKRCPCRNRKWFPPVPVANRRRAANQVTECTLRSLPSLAIGGSYGEKSLKQHCKGRQPFEEHYHTSHFSNINECSIWQHIGASVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1T7</accession>
    <name>A0ABQ8V1T7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Meiosis protein SPO22/ZIP4 like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013940">
        <property type="entry name" value="Spo22/ZIP4/TEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08631">
        <property type="entry name" value="SPO22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="968" mass="107215" checksum="55FE10C832CE560E" modified="2025-10-08" version="1">MSGTRKKKTLPNLQEIFESIKDLLSTTKTQLDASDISLRPSIIENLERISNLAESFTDRRLKAEQDCANFCDILDQEGAYDKKSSAMHLVTSVSGVTLWNISGLVSKYPDDDGRALAGARTFIKSGDLSAQPEFVQIPVRLAAFRLIEAGLEERPGIETLIHVLGLASKTGAILSELGQFDVAGGVLASAAKYEEMMRVEDDPEDSDPQKAWKEGNHTVSEFMAQKLLAIYDEQRLVFPAHDRVLLAAKFHDIGKSALKNQVGKIQDKSSDATAWLQKAFGIVDQEESSVPNALELRISILRTLARAYFLSECYDSAEATLEELTPSLDASKDHASSEYQELRWLKLAILKKRQSGDTAIHDAFKSIINHMKFTDTTVTDILRELRTLGHQHTLVSAVTQNLLQRALQCNEKESESVDRVLLSLIVHCSKDEVHSRAMEVIGKAFTSVCETNTELRSISAAACLSLLWQYGDRHYHGKRWSQAAEWFAAGGHPLFKVHGSSSASKSYRKAALCYIEQREYSRSAAVIRSCPSNEAATHYLAFLIATYQAIKSMHAMVNAPDFDRQMLLLATKISHESEMKNVLLAILEALLTTLKISKSGETVIEAMALLRCIIRLILKLLAEPIAARSTLIDSVVTHFRTAKILVDAAFEQKAVSLIIKDVSWLWRTAYNCAVQGCSDWDGFQEQISALFDISKDMLEVYCQASPVEVEPDLYVHLMNALFSGVAGRAREASSANGSINVRTAALVVVATAHIVQGQADTRDIRGDPVVQSKDLTNHREVFEAEILAQLNDWDQLLKTIADAVTSGQLAVATYEAIADILWEEKGCPVNVLCGGLEAVLHATLDHNSLSLEKYARWLRAICTITLARNTSADRLKAIGYVEQAVSMMENSDADKAYPMDERFWLLATSYNTGFECLEASSLNEAKRWFEASTVICRFVPGGTERAEKISETYAQLLSSLHSVYLVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V213</accession>
    <name>A0ABQ8V213_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_781947</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF13">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="5">
        <location>
            <begin position="72"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4465347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="475" mass="54938" checksum="C8BDC137B1BFC4DA" modified="2025-10-08" version="1">MSYLKVSGTQFVDGAGAPVVLLGAGLGGWMMMENFISGFPGCEFHIREALAEAIGVEKASLFFEKFLDNFFAEADAKFFKSLSLNCVRIAVNYHHFEDDMNPRVLKIDAFKQLDRVVTLCAAEEIYTIIDLHSTPGGQSGGWHADAGTHFGNFWKHKDFQDRFVWLWTQIAEHYKDNIWVAGYNLMNEPADPHPHHTGLISIYDRTYAAIHDIDPNHILFLDGNTFATDFTKFPEDSATRWGSNVAFAIHDYSTFGFPNSPEAYEGTNDQKDKMKASYARKRKWMDERVLCVWNGEWGPVYGREVYDGEQTEDINRRRYMVLKDQLEIYRKDSLSWSIWLYKDIGFQGMVYVSQDTPYMKHFREFLLKKHRLAVDAWGADDKYVKPIYEPLINLIKEEVAEPNQKLYPPIWSLENRVARISRTILVAEFLVKEWAELLIGKSDKELVDFAESFAFEKCKKREELNSILKLNALEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R1</accession>
    <name>A0ABQ8V2R1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Metallo-dependent hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_853650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052349">
        <property type="entry name" value="Metallo-hydrolase_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32027:SF0">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="57494" checksum="33D8866F3C6F8B64" modified="2025-10-08" version="1">MWWMGRQRAPLSGSSTPKVATAAKILFITNVHLAYPDPSFACKLWSVECREGNVVRVAPYIEGEYNPISFARYEIDARGGILLPSLCHSHIHLDKCFILDRCELIFGDFKEAMSVTGSAKARFPLDKEDLLSRGRKLIHESVDCGVTSMRAHVEIDDLVGFSGLDVALHLKEEAQLACHIQIAVFAQEALFSSAGDAEPGSNFRLLAEAVMRDGVDAVGSAPYVEPTIEQAKKNIELIFELASHASLTLVDFHLDYNLDPDSEPLIYEVVKQARKYCPAWKSHGPELFRRHITIGHATRLQLFTPKEWRHLQDAIGDLPITFVGLPNSDMYMQGRSQAGEPLGAPRSTLRVPYLSDKYNIQIAMNVNNVENAFTPQGSADPLALCTFGAAIFQAATKTDIQTLAKSVTITSKVAIGQTNVPLELYPQRGDIADFVILHGTQTLRQAVLNSPYDRTTIRNGIVVAHRRTRRWTAIKELPVSNTVDPISWWWYLLFPVSWPFLLLDNWASGPPKFLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V337</accession>
    <name>A0ABQ8V337_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Peroxisomal membrane protein PEX14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">Peroxin-14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_781113</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peroxin-14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025655">
        <property type="entry name" value="PEX14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="12">
        <location>
            <begin position="40"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4465903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="401" mass="44898" checksum="D7B8F3D33B34B1D1" modified="2025-10-08" version="1">MAEEDKSTTSPPAPSEPLQESGSQSGAHQPSQSTVEENNRSELILRARIFLRSSQIQSQDVFAKRRFLLDKGLNENEIELLLRELPPQLPRVPPRTYPQPLPSGLLTLLIGLARLLTWVAGGSAALLLLYHKVLLPRIVRTAEARKSLKMHQINLLQKLNASLQSFKETQTQCYAPLPRPVPHKEHSTFASCHGLLDVLKESETQNLQVNQLPQITLLRCAWEDFRALPGCADSNPRTEELFQVLESRIPWLVSDEGLAFERTLWDVLSTTPVFKELISQDSLEGATAPVRWVYVPPEPVVPTAFISSLNSLSKAISTFQYPTTSSPYQYTLQAMTEFTGYISSNLYTPYRPPSIPGTIASSIEPADEMKKEIRALKGLVLNRRSFMPTIPRANIPSRQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3G8</accession>
    <name>A0ABQ8V3G8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_636021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000099">
        <property type="protein sequence ID" value="KAJ4468930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11885" checksum="BDB68F4F667D2118" modified="2025-10-08" version="1">MWASGSRSWLHPVSVLQVFSVQWFLLLCFSPYLPYLGISIPNMNNYNVCQVLPIAYHSGVYHAVSFLPYMEQFCAPTREHWEHEERRLVVIDSGQNHRHHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3T3</accession>
    <name>A0ABQ8V3T3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_782286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000133">
        <property type="protein sequence ID" value="KAJ4464854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="262" mass="29297" checksum="EC9F88AC45446036" modified="2025-10-08" version="1">MEASVISKTQGCKHNNIAEFLDWAHQHRLHAKDVLPASEVILCEYAAEFRGKLAGASVKAKLSAIKGWTIMKGYTWQGGDCLRKVLTGVERSAPPSSFRPEREPVKKSHLSILHAELDLSDTNGLDCCIAAAADLMFYSQLRAGEILPTNSSFSQYNTKFMPKISDLSKTNAAGLKRLFLPRTKTSQMRGDKVMVPVQKGSTNPIHSLDNHICVNKLRPSDPLFAYTDTKGIKRILTRTLFLRRCNTIWGRHNISRRTGHCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V410</accession>
    <name>A0ABQ8V410_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_970811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF140">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047245894" evidence="1">
        <location>
            <begin position="18"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="308" mass="32803" checksum="B5F7058BF1FBD381" modified="2025-10-08" version="1">MRLSALFTLSTIYGALGVSLPTKRATICNGHAELCTRPYGNTTFLGSHDSYAFSSDPLALARDQEVDIPTQLGLGVRFLQAEGHLNDGVLHFCHTSCLLFDGGTVVDYLTTVKTWLDANPNEVLTLLFTNSDGLSIPDVWEPTFVAAGIDTVSYVPPNNPMTRSDWPTLGEMIDSGKRVITFMDAGADGTDGAPVDYILPEFTMLWEPPFDSTEPSFPCSVDRIAGPLSTVDHLNMLNHNLDINVLDTGVLVSDPEDASTTNGVASILADANGCAPLAGGVAPNFVMLDFVNIGAGLQAVDELNGFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V443</accession>
    <name>A0ABQ8V443_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_581161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="27847" checksum="3B984F1FA54ACA04" modified="2025-10-08" version="1">MKHLRPWRFHFLRHLRISHCFLAYLCNYRKFSLHRGVYVRYTTGKIFFFPPSLFTINDTLSTLQFDLELSVMTAPLTAETIFSFSLIVGPIYGTIIVELLLYGAFTVLFGNYLYLQARHHGRHRFYQISLTFLYLSATASVILDTIAGREIMLYVLDRLDPFYNDSSSSRYHYYSQTNLRNGSVCDRKLRGRYPPSLSLLCHLGLKEAGNCWSCSGVLPEYCRRGCCYLLSETRRRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4S1</accession>
    <name>A0ABQ8V4S1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clavaminate synthase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_888800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="57275" checksum="735595684F279A33" modified="2025-10-08" version="1">MVRTTRSGAEFSPYELGTPIQCDVDVADLLRLRYAELDAQGDGGDVIDSDHALEAPIRPACTPTKPPNNVKAQMQPPLPRPQVSPPHPSAPASKSHQQNFASAACPAPSQSQCPAFPEMASECTAPLHPPQNSAPSTAMHRNARQSGSHGRRKRKRELSTHIPTVEKPVHAKHRAHAYAQAIQVDLDAAMLPVNSTGFGGQNQVLACDRRDAETLCSQPGWCYIPSPPAVPTNTAGQNKGDGVTTTGAIPIVDRHGRMVVLIAGSPQMHWQSEVAEPLAEAIAAGSSHLKFSSEKLYHKRGDGFAALASGPSHGGGESFPGNRVLSPSERSFMDMLLEHPAMQRASGFMNQILHTYNPLMYEDYRLHQEELHVKEPHLRRNFPNSIWSSLTVNCGPQSVTNPHVDGRNRPDGWCPVLSLGPFNHRLGGQLVLPDLKLAIEFPPGCVIFLPSALLVHYNCPIQEGERRYSITQYTAGGLFRWVANGFQTQEAFLARATAAEKKKWRLNRATRWEHGLRFFPVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4W8</accession>
    <name>A0ABQ8V4W8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 20-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_848348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="480"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="924"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="960"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4474202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1041" mass="114949" checksum="988A6ED5417F569E" modified="2025-10-08" version="1">MQMPILPTLDDIRASIVQLEDRHRRNGVVLSGRILHVCHSLPVTCTLHIDKGEGSSSSRKWKLGPRYGHAAMISGIRSLSATHEQIIVGWTGDIEGSEDEKKEVGQVTEDDRTQLNELLSKGGEEDDVHEAHDKGHHHTSYAAVWMSSPVAHGYYDGYCKQILWPLFHYLLWQDVATEYASADSHYPHYEAANAAFARRIAELYRPGDLIWVHDYHLLLLPSLLRELLPDAVVGLFVHTPFPSSEVFRCLPRRKEILDGMLGANLVCFQNYSYTRHFVSTCIRVCGYESQLGGRGIENPSSSHVTAVSYCPVGIDAERVARDVLRPGIKPKFDALKTLYQGKKIIVGRDKLDVVKGVLQKLRAFEKMLQMYPEWVGRVVMIQVTSPSLADSPKLERQVSELVAHINGTYGSLDFIPCHHYHQTLKKDEFYALLSVADLAVITPLRDGMNTTSMEFVIAQERTKRSPSVLSELMGVMGILGPKGPGDTNESGEEEPISPGGLNGHGSPASPNINLANNKMRLNGIDISKRKFAWNSNSPSVIPTPTPVVRGDPIAYAASAYTANDLNGKSGPALNGFSNGSDNDSSSPGCSTQGALWVNPWDLHTVASAMHRALLMPEAEKATRHRYLYDVVTTRTSHMWANVLTEMLLQQMTPSVHGKSDANATGGSKRGIPYLDIARLRKWYDAASTISSSASIPRQPTHPRVKPTRLFFFDYDGTLAPIVKVPSAAVPSEQALNALNNLCKDERNLVYIISGRDADFLDEHLGSVGTADGGRGLGFSAEHGGFVKEPKSSPDGSASLWRNFTSKLDMSWMSEVYEVFRYYTERTTGSHIEVKKSSITWHYRGADPEWGQFQCRQCQDLLENNVAHKRPIEVLVGKKNLEVRPIAVNKGEIVKRLVYKHPEVEFIFCAGDDKTDEDMFRALRQFTERPSSSPKTEDDSNGNGNGKVEFVMEAPLSVTLVDGDDEEGPGSPTNNTSLNGKYPPMKIHLAPEAVFTVAVGHSSKRTLASWHVPSPAEVVGAVEGLLGLITPEEASDQSQRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V538</accession>
    <name>A0ABQ8V538_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="188" mass="21046" checksum="9D480C8ECEBD3A09" modified="2025-10-08" version="1">MTPVEQELISSSGQIAFFNSRYNSYSHWICYVNENLACKITISIAAVFLGKLSMSNTGSVTNVLVFKVLFMVFLCCTTDTIYFGGFNLTVIRSMFIWQSFPDTATAMLVDSTDNAGGQFTDSMETMAWRYMPGWKWTATVNNHLAGLGFERDILGCENSCDGSDNIQDMVRDNNNNEIPLVYILTNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5U1</accession>
    <name>A0ABQ8V5U1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3835 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024325">
        <property type="entry name" value="DUF3835"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12927">
        <property type="entry name" value="DUF3835"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3835" evidence="2">
        <location>
            <begin position="368"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3835" evidence="2">
        <location>
            <begin position="687"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="703" mass="76597" checksum="023A6EAC30D7BEE5" modified="2025-10-08" version="1">MASPNQAEALNNTEALQTLLQSFGPDAAQNVSQEALQRLSDKLSELMGADVVRDAFAYNDQDRQAVPTGSETLLNEEGLPIIDITEPEAAHVRSQIQSSSSSSDPSDSPITTEAPPLIDLSTLSPAERDLRKRERERILDLLEAEEVLEQRSEREKEAQERREALDRKRDDGKTERQRLLELKETHQKMGKALLRSVISDDDDTKKAETQPSSFSPASSSAVKETAVTTNIKKKSVSFASEDPTQVEPSEVSSKTSTDIADWGDFSKGRLRPNPKPLVADVYTRQSEHLMKLQVVERAPGDGSTSFQSNPLAENKQPSTSKIQILDSSAGDSDDESDMDSNTLSDDDNVPQNSDTEHSDAESGGLDLDEETDWDFAQHQREIALEYHQKRGKIGKETAAALTSHTHVPDEDPTFPGLASNKPKSSSSMSQFRANRLASSYAVANTDATSSVPSPLGSSTLPTLLPAGAAQTLQHAVRLGKLDEQKRLVGGDTGDSGSEPDDEVAREILELLQKGEVYNLGPNGEDLHVVRPNTITSGSGGSTKQSTRAQPPRSDPLPPFTSPIEPLPQKPKTSRFKLAKTQSDRLPSPSTSVDLSGSSTPVSNARRSSPKLAMESSVVERAVPQPSTSKSANYTNVPKPPIFNSIVIESPSFPRSAESQRRPERPPTIMSSHVVESSPQRNDNSTTRMDEVPKRVSRFRAERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V681</accession>
    <name>A0ABQ8V681_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Autophagy-related protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_869935</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF49">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="14">
        <location>
            <begin position="438"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="14">
        <location>
            <begin position="792"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="201"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="341"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="640"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="857"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1087"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="256"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="358"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="672"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="705"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="749"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="870"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="890"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="964"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="980"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1026"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1087"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4475447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1115" mass="118598" checksum="F66CF5F9A276C5F3" modified="2025-10-08" version="1">MSSKHSRHSPSPAPSSKLPKFLQKSRDRSKSVNEGVLSSPELPSTPSPSSSARPSRKNTRISEEFGEETPVIVEPVSIPSPRQRNRPDRPPSLETSHSISPSARMGDLPTRLSGWFSHTFSTSSTDLSLPTILAQSNTVSTGSTSSPRARMTGASALLTAAKHGKGHLDKAMRYLLDSDATPDKCTDVIWILGVQHPGYEPPLAQSQLPPSSFTSGTLGRRGSVASTTTSDQSHGHKRSRSRGQHAHSSSITHSGSQFLSQSQPPSSSPSQSLSSSVSSVTATPSASVYNPALSTSSTQSATSKDLKPGANWPPDFYADFTSRIWLTYRSHFPPIRDSNLQELTPPACEPIMGPAIIPTPASPSTLSTTSNASRRTSSRYTDSYKSDSSLSTSLSNTSHTKGPSSPTSTMTNRSKWNWTVGGLGGEKGWTSDSGWGWRDWRVPLSPEMTREYAMYVQIVTWFLDTPSELAPFSVHRMALAGKDLGKDVGMWFGPSTAAGAIRSLVHAYSDAGLGVAVATDGLLTQTDVYAASHGTASSSYPRRGKGAAHTSWGDRPVLVLFGIRLGLDGVNPIYYDTIKMLYTFPQSVGIAGGRPSSSYYFVGSQTDNLFYLDPHHARPAVPLRPPPTIALTGPGSAFSAVHISRPSGSSSGYGTTEDAGDEREVDKEKIKKVSTKKSHKHSTRSSSGGSSGSSGGSYQGLQAMSGSPSSTRTGSSFHTPLAPSPLQQQYSRSPPVAGNHGANPPHAGSTSSSSQSRTESPASGNSGDMDYSELMGPSVPEHDLTPLEEHYATAYSAAELKTFHCDRVRKMPLSGLDPSMLIGFLCRDENDWVDFRRRVVQLPKTIFSIQDEAPSWAADSADNMGLESMSDPDEVDTMELEDEDEPSLDVSIQSRSRSASLSLSSVSQHGSAGGARSDRSKSEEIDTEEDPVDPITPGPSATRFDSSVVHVPLPSDGHEKESSFDDASDDIEDDWVEPSIPSTPVHSSHGAQSSTDDSAGAVIAPAMKKTRSTSSGASKKKKPKKQIPVPVPKVKLPSTRESFPFPVATEDVAAEGPISVSYSSSSSMSGAGDDSVGVGALIREKRMNNARARDGGRTQSGGVKGVLTDDWIDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6D4</accession>
    <name>A0ABQ8V6D4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045518895" evidence="2">
        <location>
            <begin position="17"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="344" mass="37180" checksum="4ACE533698FBE2AA" modified="2025-10-08" version="1">MAGLIILFFLATSATILDTTATMKQIWLYLGQYWGGQSSLDAETASSMTVRLDIICGTVTFGLYVISNFIADLILIHRNSVLWNGSKWKTMIWVPLVISIINNVLGIIGIGLEASNISVYPSLSVSFDQYTNGDKIVLAYLFTNACLNLLLTGCLAGRVWWMGKTAELALGAHPLRQKYHSAVAITFESGILYPVALIGSVAATLQNSTAPSLYPFLIQIACDLVQAIAPTLIVVRTVLGISIEQRDMGSYEEVSSDTILSTFSHNGDTMPAIHLANPSKVSPTSDLIPYNSLPNPTPILHSAVVVTPGSVLMSLLSSNRQCDCDNVPVTPYPTPWHALSFSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6X8</accession>
    <name>A0ABQ8V6X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_849486</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="95"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4472704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="421" mass="44317" checksum="1425E055DCD0B1E5" modified="2025-10-08" version="1">MSHHHVVVKSLPFTSALGRTKPVSHFRHIVEHDRSRAQKFMAGLHPHGPNPFVEARKRRHGHHHHHATGGSGAATTPSGDSNSDSIDVTDSAVTYLMDVTIGGQDFSLLIDTGSSNTWCGANTKFEPNSSVESTRESVNVSYGSGSFSGTEYTGPVVLGGSSGLSIPNQSFGVASTAQGFSDTDGILGIGPVDLTQGTVSGTSEVPTVTDNLANNGTISTESIGISYNPTTGEDIANGELTFGGVDQSKTTSDVTYVDITSTSPASNYWGIDQTITYGSSGTTILDSTAGIVDTGTTLLLIATDAFQAYQKATKATLDQTTGLLKLSSSEFSNLQSLFFQIGDTSFEFTANAQIWPRSMNSVLGGDDDSIYLIVSDLGNNSGSGLDFINGFGWLQRYYAVFDTTNTRVGIATTPNTDAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7F0</accession>
    <name>A0ABQ8V7F0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_870523</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Self-assembles to form functional amyloid fibrils called rodlets. Self-assembly into fibrillar rodlets occurs spontaneously at hydrophobic:hydrophilic interfaces and the rodlets further associate laterally to form amphipathic monolayers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045003271" description="Hydrophobin" evidence="7">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00093546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4471922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="109" mass="10778" checksum="55A7A53A60C50039" modified="2025-10-08" version="1">MQFKLAFVTAALATLAVATPTPRNEPASSCSTGPIQCCDSVQSASSSPVAILLGVLGIVLQDVNLNVGLTCSPITVIGASGSSCSAQAVCCEDNSHGGLISIGCLPVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7G4</accession>
    <name>A0ABQ8V7G4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_923715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046110153" evidence="3">
        <location>
            <begin position="25"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4475112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="497" mass="54478" checksum="6B9962C284EC4DEF" modified="2025-10-08" version="1">MLLNKPGAWPVIICLLWNPRTVLASDKQPQVQWISPSAGDVFTSGDSMLGKWTADTAVVSPAFKLCPGGPQSSLKSRADGTGDDGSDISCGSKVYPTVQQSSGTYSISLAIPNTTTDQTWHLEMSDDFANTWSSPSFSLSPSGSPSSAPAVGAQSPLSPQSQTPTYPSTTSGPVTASSISSVNPESASVATMLATRTPPPTAAFAIPLSIVGAILLVAVFLSLKHNRKLAEERAQDVEKLVLSRKSSVASSFKSGFSRQSEIEHALNVLSKAQSQGNVKPMPVPLFMPVEIPVPKREARRSTREAYFPIQYTEYNQRPRPRQEVRYHERPPSYHTAPLSRSQSRARSLLSSDYSSSRASSRTAVHPPSHGHHSACQSSHRLPSLRVASPLQYYGHCSDKHRERDQHCDQRHSRSQFEGRDHDIECATHSVLDDYLPKPNPHDYSPRPPVCLMPAPQRLHVRNNSAMSSRSYDEEEEEMMEVDLYGAVADSLNRARRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7V7</accession>
    <name>A0ABQ8V7V7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynamin stalk domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin stalk" evidence="1">
        <location>
            <begin position="113"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="21726" checksum="8D2470693253C602" modified="2025-10-08" version="1" fragment="single">QINGIKTADASHCRQLKVHTGGSAPVDFTENSAARPLGEAVNIVGRDFLPRGTSIVTRRPPTTTDAGQHVIAALQVLQLIHRPSTAHQNGGPPELGEDGDAAANADENMTLDSSKSIALALEAECNFFEKPSVLQRKSTILMHPIRATLPDIKARISSQLQKYNAELMQLGGFMAEHNSGDVVLSVITDVHTCSHSSTGVIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V829</accession>
    <name>A0ABQ8V829_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_772367</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="3">
        <location>
            <begin position="27"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="4">
        <location>
            <begin position="189"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4478591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="301" mass="33227" checksum="48FC160DAA530EAA" modified="2025-10-08" version="1">MAVASVSRSIVKKVLAVETPEGAGALVRRSIGSMTLRNLSPFLMLDHFQISKGAGFPDHPHRGQATVTYMLEGTSRHEDSAGHKGTIETGGVQWMCAGKGIIHAEMPVHEEGLPDPRGMQLWIDLPREYKMVDPMYQELGPKEIPSAYPEGPEGPVKIKVISGKSHGVESPVRHLGGCWYFHLSFSKKGIAVFQDIPEEWTAFIYIWKGSVIVGNDTIPAESFHTLVLSANKGETGVNMVSGDDDTQFILVAGEPLDQTVFQYGPFVMTTREEIQKTLMDYQMGRNGFEKAHTWQSEIGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V848</accession>
    <name>A0ABQ8V848_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_897101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="440" mass="50334" checksum="E1FEFA7F798BB739" modified="2025-10-08" version="1">MNSQTVLLHPRPYARHSGSLILLPLLQPRHISAALPTEIWTQIFEVIDHGHKSTHLLSVLLVCKKFKDIVHPLLYSRVSFQHFHALEKFSNRINDAESKWDSLRRVPYSAPGRWVQSLDVSRLELYRHIPRHHLLENPLDNMELMALRLDSLLSNLFPVLPFLSEFLMNPKFIFSCRAFMSLNERNGVNKLRSLRGIFYIPSHGIPREALVDLLRNCPNLEELEVIGPDIDASEHDVMSLWYGQAPSPPSFEPLYLPKLRELTLLASLQLSPLMLCLLSTPLPSLTKLTITPYDDIPSSGSSIFIFSHGGTLQSLLLLTRKSWPTRLHPSPSTLLQTSPTLRHLSLEIPLPALELTEDHELEILSIPKPSHDSWILISRLLSHLPSLKAVRIRDIKWLRRGMGPRAMEAGVQGEMREWRRRLARRGVRVLDGEWQDADSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8D0</accession>
    <name>A0ABQ8V8D0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uracil-DNA glycosylase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_904455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10028">
        <property type="entry name" value="UDG-F2_TDG_MUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015637">
        <property type="entry name" value="MUG/TDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159">
        <property type="entry name" value="G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159:SF9">
        <property type="entry name" value="G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="5">
        <location>
            <begin position="159"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="67"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="279"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4479870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="42728" checksum="7C1CECB9963C7CDB" modified="2025-10-08" version="1">MAATKIPVVPASALQNLRRRKAGFQTPYTPGATLRSSTIISSTSSADIVPRLFPVVEIQIPAGIRTPAQTAHRSSKNNKATSYALGSKRGRNSDEEEEQREEKCTEQDNDEEVTPTPPESKVPACSAIPLAAKRTRAGPKGFPSSKDERPTGIPDRLLINLDIVFCGINPSMTSEGNKSHFSGRGNQFYSCLLHAELISPGTTFEHAPDLPRRFSLGLTDLVARATASVKEVSAYEKTQAVPGFLRKIVECRPRVVCFVSLGIGETVCKALQCQWAKPKAPREAKTRNKKSTSSSQTSNLIEWKSRPARPEKSKAKSPPSNENSHPQIEPVTTSGTVTETLFFALPSTSGANACSYNLADKKQLFAELHAQLQLIKHGSPDAPDTKRVLDTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V907</accession>
    <name>A0ABQ8V907_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_474875</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13279">
        <property type="entry name" value="PH_Cla4_Ste20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="12">
        <location>
            <begin position="142"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="14">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="681"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="74"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="377"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="466"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="538"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="609"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="710"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4481305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="954" mass="102542" checksum="40B440BF753DABDC" modified="2025-10-08" version="1">MSYLTQTALTPSRPAPKPNDNNAMYTPNTSSSSTSAALSSSGYNSALSYSPSTPAPSSSAYNAYNSNYSGIGGVPSAQGSTPSRMNSVDSTATGSSNGLGGGGGGGYGSGSGMSSPGLQSLSSYNSSSNLRRTGTSATDDASIIRSGYASVKEDGTFASWIWKVKWLILKEQTLTFHKSESSNTPQTTIPLKDVSNIERTDLKPYCLLLEAAPNKRFFLSLRNDEELYTWQDEIYSRTPLSSFSQPTNFVHKVHVGFDPISGAFTGMPEQWSKLLTKSAITREDYAKDPQAVLDVLEFYTDGLKKREMEEMGMGVGVSLGGLSTTNANAAASSSSLGLASPARFNAGTGLGGASTNTPTTPLSSAAARAADIVANGATSSLSPQRTPLAAPPGALQASRPAPPRPLLTGQRTAPAAPGLAASGTAVSGHAHTPSSADLRARQKAVGPREPGSAAPPPRGDSLASAEIREKEELERAQQERRDRAEQDKRDRERERENERERERERDRREKERRDRDRAERAERAERVERIERERAEALEAQQQQQQQLSDPSTTQSISTSRSRDRTPEPPAGARPPANPLGGAGSAKSTPANVGGAAPPVKPLQPAKKVQIEDGGRKDKPPNSAGVAAAAAALNGSSANGTTGTNGTAKVEKEKRISTMTEVQIMAKLRSVVSDEDPKTLYSKIKKVGQGASGHVYVAKTLATGRKVAIKEMDLSHQPRKELIVNEILVMQESQHPNIVNFLNSYLVKSNELWVVMEYMEGGALTDIIENNTLEEDQISSICFETCKGLTHLHSQHIIHRDIKSDNVLLDSFGRVKITDFGFCAKLTDQKSKRATMVGTPYWMAPEVVKQKEYGAKVDIWSLGIMAIEMIENEPPYLDEEPLKALYLIATNGTPTLKKPESLSRELKSFLAVCLCVDVASRATAGELLEHEFLKKACALSGLAPLLRFRTKQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V943</accession>
    <name>A0ABQ8V943_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_475733</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="124"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="128"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4481333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="38996" checksum="4937861BC3C649C0" modified="2025-10-08" version="1">MATTSVPLSNVDRGSALLIAQLALDDIRELRGGNTYPDQEYAWELMAEEFAQVLSFFNDAQTAEHPNDEGYPTSDAVSSSSSSYSYDELHEASSSSPSTFPPSSTASELVYSCQDSHTGHLTEPIPECVACTESLDEETPLFVQPCGHHYCGSCLTHFIETCINDDNLFPPKCCGSTMSFITEKNDHSSPMENPVQPFEKLVIGSDLGIRFNAKALELDVRPEDRVYCPSPRCSTCLGSWGSLKQSYNVPDTLYQSSSNPSPPPSHRCPSCLEQFCVLCKDPAHSETLTCPIIEEHLAEDKLRDLARLNEWQTCPGCKALVELTEGCNHIVCRCRSEFCYHCGSVWASICVCRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9R1</accession>
    <name>A0ABQ8V9R1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_886121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="20"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="30013" checksum="6D60BADDFDE91A0B" modified="2025-10-08" version="1">MMEGNLRQLKRSPSFFLSGGDLHLVVNEYRFRVHSYFFIRESQHFRQRLAISDAFDLHGNGSSMSSAVVLDDYDITPEEFESFLKVFYNPKYYFYDLERPYEEWASILKLSNLWDFPNVKELAIEELQKLDIPLVDRIVLYQDHDVDSKLRVPLYAELASREATLDHDESTRLGFRTTIVIFQARERLRSLASGGKSPLPDEVGPDAAKEVITNLFKALPPLGEATPPATPRPRLNGLDSPRRPSSGFGFNTHSRNPSVSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9W1</accession>
    <name>A0ABQ8V9W1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_575609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="105" mass="11649" checksum="B75327B1B49BBF00" modified="2025-10-08" version="1">MSTRYRTIMGIPAFFAFLETLLQQPKGHSVKFCAIQVLSSDPRSPYLDSNMSLCCRVVRHYAFQKPSLSCISGRLPDSLSPSTSPVNLVIDTAKSSLTFHDLIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Z7</accession>
    <name>A0ABQ8V9Z7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_840711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047166666" evidence="2">
        <location>
            <begin position="20"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4483142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="121" mass="12633" checksum="42AC3AB7AB73B3DE" modified="2025-10-08" version="1">MKFFAVFITSALLATVTSALPTRLAERNPAHRFQGSMPPPNSPHLAHYNGTSDGSDKENYPETDAESDTITAASTSTTTSAAETTLQSSSKPPLPVETITTTTTYSIVVPTSIGSDATALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA46</accession>
    <name>A0ABQ8VA46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_453486</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4483994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="56871" checksum="2181E20005CCB739" modified="2025-10-08" version="1">MTKKKYESLPFLILVVSTSILIMCLTSLLLLPSELGLTESYPPGPKVVNMPTLNAWVKYRDWGNKYGDLVYLPKWNTLITNDAGVAIDLLEKRARIYSDRAMSPIMKLCGGENLLSVECYSDKWRRDRRVFQQTFRQAAIAQFYPVQYNKVHEFLRKLLLTPEDFMQHINGISQGLIPKALYGLDIGPEDALARKVAEIIDTFGKALLSGSFPAYEWFPFLIYMPSWFPGCGFKQIASECGKVVEEIYTVPFDLAMNHLQKGSRTSPIVELAMQKPQDLKEIKAMGTMSIIGAIDTTMSSICSFILAMCLHPDAQTKGQEEIDRVIGKDRLPTFEDRRHLPYVEAIYREVMRLHPPVPLGFPHISMEDDFYRGYHIPKGCAVVANIWAMNRNPNVYQDPDEFLPERHLKSAAGPFESIDNIYAYGFGRRVCAGRYMADNTIWLTVASVLAAFTMGKAKDGNGNEIDIRGEFTNHFFRYPKPFKSSILPRSRVAGDLVLATVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA53</accession>
    <name>A0ABQ8VA53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA ligase</fullName>
            <ecNumber evidence="15">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C8R41DRAFT_541312</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07903">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18435">
        <property type="entry name" value="BRCT_BRC1_like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07968">
        <property type="entry name" value="OBF_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044125">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 15 20" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="18">
        <location>
            <begin position="370"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="663"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="905"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="777"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="840"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="779"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="845"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ4476172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1015" mass="115683" checksum="1D00DB55F7925811" modified="2025-10-08" version="1">MQPTPAPTTPPRSPPPDESLFPPAPQNSRGPSPPFGALVGLFDRLQNERKQDKRKKLLNAWFNHWRSEVGDDLFPVLRLILPQKDRDRAIYGLKEKNLAKIYIKLIPLNKNHDDAKRLTDWKKPQNNKASSAGDFPGILWDVVHKRSSVVEGTLNIEELNDLLDELSNSMGKQDAQMKILQRVYNRTTAEEQRWIIRVILKDMIISVKETTVFSVFHPDAQDLYNACSDLKKVAWTLYDLNHRLNADDKTVRLFQAFTPMLCKRPTKTLEHTVKEMGGTEFLIEEKLDGERMQIHKRGNEYFYCSRKGKDYTYLYGKHRGTGSLTRHLDDALDDRVDSIILDGEMLVWDPVSERNLPFGTLKTAALDRSKKENNPRPCFKVFDMLHLNGQSLLEKSTTFRKKNMRACLKEIQGRVEFATEYKGKTSKDVKSRMEDVMAARGEGLVIKHPRSKYVLNGRNSDWIKVKPEYMEGMGETVDVLVVAGNYGTGSRAGGVSTLICAVRDDRRADDEDGADRYSTFVRIGTGLSFADYAWIRSKPWKVRDSKNPPEWLQTAKKSQEDKGDMYLEPDDSFILKIKAAEIVPSEQYHLGYTMRFPRALIIRDDLDASDTLTASELLESIRSEKKRKMEDTTGVAKKKRKAITKKIEVLPTFQGPKLKDVNILTDIFEGLTFVVMTDKRTKDTEKNELVKIIHENGGKRAQIAANHGSQDLIVVYKGREDSIPRDVQVVMEKGVYDVVKPEWIIDSVTLGHRVPSKSKYFIDAKSGVETDEYKAIEPVQDDQDEDMPEGDESSSAVVRAETDVRSQTAATEIKEEYEQDEKHADWFHLDITDAQHLEIGKESESETEDDSDNADVAGEDIAGDNVDDWDKLDADDLPSAPLPMDEDIDVNNVPMGEDDGAMEYDLDVIFKHLCFYLDSPQNAARQGMAVKPKYEQEINQSFDVLRDVIMSHGGRIVNWDDPKLTHILIDKRDTSRRLELMKKTSTPKHRRLIVSDYIQACVDEATLLNEEDFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAA6</accession>
    <name>A0ABQ8VAA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_456945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="655" mass="70986" checksum="C52D96994FA07223" modified="2025-10-08" version="1">MHSNEISFPLIHPALSVVPTTSHIGRRNARRPLQSSPLTGPALSSEGAVIQEDHVLGKPRPSRISSLPEFSKSTDYRVESIPPLPFSESHQRKSLPPAHLTVFNSNPLPKTSSSYPSKPPQPSSGGHTHSLSQNISHAPHRTSSSLHDTGETWFVTSTYEETPRFSRPNKGTTVVMPVSVKEHRRKSLHSVKSQPSLRDRSANRTRDVPSEEGAFKRTIQPRRSLSSLPSTVRQRASAIMSLDIDVADSCGNAIPRQPYSTSVTSRSSSSTKNISDIDSFIPSPPPLPPSDSTHSSESFISNFVIVDDAETIQPDSNDPVLQGSPVDLLPLQPPDHQRSASNTPSKSRTVSIDSRNSFGAFKWRTKDVSRKSRSFVHSRASSSVDPILGSTVSSPFVAPRKHVKGFSFLSFSSSDDSHSFHVPPVPGSLPDGIGMTTISDTSSDSDLASDDTHIDYQKEAGQLLYDAFPRPPSIDYNAISSMLPAPLSDHNPGNFRLLPKTLPPELDLNERLGSPLPRTPTPSSPTRSSSRTLVSPLTPTFSPFKRGNTDQILPQNIGLGGRPFASMLDLSSTSSLRDSPTASFLSIEDDNVIPTRVSSRSKLPEAASAKAMNLLGVIDGPSNQAQAAIPRRVGTMKKFWKNLTGGEKDLVKSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAE3</accession>
    <name>A0ABQ8VAE3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6987 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_532848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054256">
        <property type="entry name" value="DUF6987"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461:SF1">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22485">
        <property type="entry name" value="DUF6987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6987" evidence="2">
        <location>
            <begin position="2"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="161" mass="17568" checksum="AF0149F6F9C6C760" modified="2025-10-08" version="1">MDVRPEEDRNEGELVQQVKPLLQQAEQIMNETQGMIKGADPENKISQRAQNHQKAHKATPEEQRLAEALKVMIEEVGGTIEWARNKLDAFPKAKKDLGPLLDALGQPLTQIVAGVGMLLAGVLNLLGSLLSGLGLDSLLKGIFAATVSCFFEPLDPSYYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAJ6</accession>
    <name>A0ABQ8VAJ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="179" mass="19620" checksum="BEF8A99855E53C43" modified="2025-10-08" version="1">MSKGGQRALTVFKKPYNKANLAGATQLLILFDLTNMSSFQAPACTPSSSVDWVFQQQFWKVYDTAIATIKRNGFSSPAPVNWAAGLQNNFTKEFLDEIYSIALTGIYYECITSQAPPAQSNYSHSISEGPEAASDTPSHYQVLGRQPMPQCSFAPSYEDFFAGLSSSSYNVAKHNSANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBG0</accession>
    <name>A0ABQ8VBG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_799429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="19655" checksum="2B40AB9BBF534B22" modified="2025-10-08" version="1">MSSTLVEIPVQVASSVASSSHISQPNAVSHTIEGSHLPLDSTIVIHDLPATMDAVDNIFGHHCQEQEALPPYIEEPPAYTPSGSNEPITLAMYLFKFGFLFPPFWIIGAFILLSPLRQPESTPSSVWLPEKTESEREEIIQKMRQAEVRWAKRCLVALCILLVLVIVGALAIWAVLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC36</accession>
    <name>A0ABQ8VC36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_845597</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046222054" evidence="5">
        <location>
            <begin position="27"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="41"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="462"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4476804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="619" mass="66574" checksum="90B09435D8B4BBB9" modified="2025-10-08" version="1">MIFQCTQSLYATVSLYLSTLVALSSAAIYDQYSDIPLGKEYDFIIAGGGTAGIALASRLSENSAFNVLVLEAGTSSVGVFNITVPYFATRTVLQYDWNLTTTVQPGLGDRWLFFPRGFILGGSSSINGMFYTRGSSDDFNRFADTTGDDGWSWDSIQQYLALNEKLVPPAGYPNTTGEYNPNVHYYHGAVDVSLPSFSQSIDSKVLDAVDELGGIYSYNEDVNSGSPLGLGWLPRTIDSEGRRSSSVTAYLSDESNDKLDVLVNARVARVVPTSNTTLNSTARYSFRTVEFTQDITNVTLTQITASKEVIICGGVVGSPQILLNSGIGNSTTLLAAGITALVDLPSVGQNLSDQAFIANAFLASTTNTYDDINRNDTVSNEVLAEWMGGDGQGDFQGAGPLGDTFANQISYYRISEELTDEYGDFAAGATSPHLEIYPGNGYFIAPPTTGYYMTMTTVVVSPVSRGSITINGSNPFTPPIIDPGYLTAKFDIVAMKEAFKIVYTFLNASVWDGYILEPPTGLPSIPDFFTMNATELDVQLESYIRNSTGSSAHPVGTVAMSAKDASYGALDPDLKVKGVDGLRVVDASAFPFVTCSHTQVPVYVFAERAAVLIKTSWQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCE2</accession>
    <name>A0ABQ8VCE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_920945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045122910" evidence="3">
        <location>
            <begin position="22"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="680"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4487414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="775" mass="80183" checksum="0D71D54E5118EEB3" modified="2025-10-08" version="1">MKGTPTCVLVLALSILQSVQPIFSSDPLTVSSNSSSSVTSSPATTSAISSTSTSSSASATASPYLAFDLSSTELDTCSPFNIIWSWGIGANPPVKLITLSVTNINVTQQLPPASSSSSSLSASSQITNTFADLDSSTDTVARRQIIPSVASGSVLATGTVSAAPGSSTQLAGLIESLSTALDPSVQSSFTWDQVNLPQGWYEFLATATDAGDVLGGVGGIWTTWNASSEPIFIRNSSDVSCLATITTSTSSSSSGATNTAGQSSPSAGGSLSTTSHVNSGAIAGGVIGGLAALVVIIGACLAYLRGRRYRNGLNDAGDGTSPRPNFGKWGALGSFDSANGSRSAPKSTVKAEGTDDFDPVTVLNTAANTRPQKSGGFSLGDIGLAAMGLAKPQDSPPSAFTTKSKRVRRTRQAKDSSGTTESTGAIMSSSFSSSFSPPSSSAHGSYDPYVDFPRGYSNTSTRQAEEDFAYSPSEQTGMPMRNLSPSSSPTEEDYSKYQSYVPSTDSLDSGAPGVGTIPIGYEPSPFVTPPPSEPASRHNSRSYSRSSLAPSGNTQAFSALGISDSSTSDGFRHNRARSQSQNVSPTSTRPMRGPDVPESPKHEFVSSAQNKRASSPDAFVYTLNPEQTQSSSSAGKAQSRRTPRKPVPSYTPDEALGAFTETVTSPTSPVYTYLGPVPTKPAKAATTRRPAPTIPASESASSSTSSFPATTPTTYQRAMNPYGSHVPALEHKDSAQSLASLRNMEGDLSAYNAVLGNEGAKHMHILIPDMPLTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCM6</accession>
    <name>A0ABQ8VCM6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="22250" checksum="837D60D4A265529D" modified="2025-10-08" version="1">MVGHHDILSQSITFKNILNAKDQIVEEVYESKDQMKHSIEHYWAPTDCCYADHLKCCIETLQSFKVGIENSRALSLRRHGWCSKKIWLGAGPGNRQNQVQNDAISGGVLQEILGALCGSLVTCRTLAALKLNIQGTIWVCRVCSRRLSARAIYPEVKPLQTWESELHGKFLYGLIIPWATGHCQSKTARPEFEVLVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD77</accession>
    <name>A0ABQ8VD77_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_835894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="34001" checksum="6D830EB90DE83503" modified="2025-10-08" version="1">MIHESRATEVGVQLKAPMVKSHYILPSDDSEITRLNLQNQLLTREVCDGKLIFAPAELEHGEQVLESGTGTGIWLLSLAETIPPTISFTGIDIHTRLFPQEFPSNVSFIQRSITNLPAEWTERFKIVNQRLLIGGLTRKEWKKAIQEIHRVLVPGGWLQCIEPNIPLKTDIGPHTERMFAAVRDLLAKNGLVHDIVEVLGRKLSKTGFTNVQTHTVSLSAHRHEEEFNHRTLMEWFFLALKPGILAQKLLQSEEEFGELMQNMLKEWDESPQVAWSWSVVYAQKRENNVGTAKFCIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDD1</accession>
    <name>A0ABQ8VDD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_981930</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="533"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="352"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="443"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="575"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="660"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4487514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="785" mass="85309" checksum="30DA7327468D8B39" modified="2025-10-08" version="1">MDTFQLRDENEPSNSVQNISRSFNEPSTSSVFEDASVFQNHTPSPHPTPSSSSSVHLPEIAQQRCYWALLSAHLVFLYLDPIMQADLGGAVVGRSLLEFVHPDEQSTARLDLSQVLESKTVHGSITHVRFSRPSRIRRELRKDGFRYSDKIYLDEDFIAVDLVINCAAEGLVLCFIHATPDIDPVSDNDERVKSSWSNWCSTPYISEEQLRHLSHNLLMCAPKSSHGRVFQILNNTSARPSLFTWPPPQEGSSEKDFTDLAKSVEFRQSGSSISQAKTNCTRRFKALQELHGTDVVESVFIPHGSVIFACHKVSTSPSSLSSSAHSQPINPTIPILNSPNYTTAFMGYNGPSSTSYSLPPPPPHQQPFYDPQYSLPPLTSSTTLPPPTSTYSYASGQPTLPPSSQYSYAHWANPDSHSSVQSLRSGYWSHGSASYENGSSVSAPLPMSGGHQSHGNYGRPFSPYGSHIPYSSQSVSSHLDGLNGNTPSPTSATSSTADLVPPSRRRISPSLSPEHRGSNGATGGPQRTHGNRPTGLIKCSSCKTTTSPEWRKGPSGKKELCNACGLRYARSRAKKEGHVVSNSGRKRKDKIIKRESSTPPSATSATGSITNSYSTSAVIPYHSSSTPPFTSVGSLRRSYVSSYDSIGSFSGNDIYGASRSVGTPSPSPPTGAATPAGGFSHYVSASSESTGHAHHPTAASRTSYYGSSVSSPLVANPPLLQTQSFERVHRDREGYPPTPVSAEPRASYYEASYNRGERKDALCGYEKEYEREYDHEERGRSLVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDD5</accession>
    <name>A0ABQ8VDD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_835842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33700">
        <property type="entry name" value="MYB-LIKE PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33700:SF30">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047088147" evidence="2">
        <location>
            <begin position="29"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="627" mass="67587" checksum="CBCF1CB7D3914D50" modified="2025-10-08" version="1">MIAFNSRFTFLAALLSLIAVSLNPLVEAAAINARRPETSSSASGTHHKTTREPVLPLPTRSEKALSGKNSEKGEKKKKEGSSKGHKHDGRSLEDEFIQILPWDHNDHDHNVISVNIKHRVLPGHHDHKDGHRNDLVDIDIKKRGEQAHFHTRRHSKFHDGKIIIDGKNDHVHIHARRHHDHDKVVVKGDNDHVHIHERDHDHDHDHDHDHDHDHDHDHDHDHDHDHDHDHRRARRFRPHPRSLETMQKRACQATPGYIDINSDGKRLASMAYNQTMQEYDVSESEASTFNLMNCGTPEASSLVTLACNDIPQGGCLTYMYNGTSEDMTCQRCVDQSSVPPTACQTFMYNVTSGQVNPTNCNMVAAQADDTDTEPNTGDGPDAGDEVPGDDSEEPDAEQAASINARDVSSTNSSSVTPVSLVFRPLAKELEVEDTGSNNTSFNSTNTSGNSTSFNATSIDSDPDSTSPNNTSTTTANQTFTTTITVTSTSTSTGSSSSAVQSAAVASPSTTGMKVEVFNDSNETDAPPFSSSTDSSVSSTVTSSSANTTPTSSMMDADAVASSIAASSPSDTMAASFTTSSSVTGTASVSASTSASSSGSPSATAAAAGLGARSTEPYLWQFKRFDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEC7</accession>
    <name>A0ABQ8VEC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="303" mass="34212" checksum="7D4FF1CF20099284" modified="2025-10-08" version="1">MYHIKNDDVPDDARGLKHAFEIHIHILWNSLSESVAPEAPSNINIANFIKCHKQVNEVLNQPKVSLSRKSLKSVVFLRTTCQLDPGTIVSAVAQVSDHSLRMSFSVLSSFGRTKWRPDVLGASPTSFYNLAISSLELGLQNGGYVYFEPNLEYIHNTAFLCQIYRNYVYSHLKKSILKESREKGRLASDAVKRVMYKRRKKVYSLSSFMSRSSKYFSQLMNSHIKYAQDSGFNNQIKSLIAEPECNSEDEDADDGSLHILVKNLCSENTSHFITHEIDKVSATGSSNRCHQASHSRKSQMAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEV4</accession>
    <name>A0ABQ8VEV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_439312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9929" checksum="F5F731E091DF8E25" modified="2025-10-08" version="1">MSDEILPGDVVAVNHGLAGRQEGLVVGSHIDYLGRHIIEVQLDSYEVYHAWHPTVTRIRRTVYNRPAQVPLIGGVPRTRTVERKIYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF05</accession>
    <name>A0ABQ8VF05_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sc15 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_370961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046972559" description="Sc15 protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="19699" checksum="E0F5D48D819B5307" modified="2025-10-08" version="1">MFFARFFALFFLFATFGIASSVPSVAAAAEVQKRQDITDIEGVFNTLKSSTDTILPQITSVGQSGKASAATVTPLINELTAALNTASSSLASLRTSNRKVRRQTEPDISLLVAGIVTDVTHALDTLLADLSIVPEIGPLLAGVDVALDETLAGLEILLAGVLTLVSVLLVNVAGLLESLSFGLTLASLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGN0</accession>
    <name>A0ABQ8VGN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_768542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26665" checksum="4C3C99E911D63BBE" modified="2025-10-08" version="1">MQDLLQNKAIRRISGFQNALFNTFCHKNYAEHMDTNDELLSQQPELRANFPKTAFAATTFNLGPLSYSPPHMDPDNRASSWCADTTMGPFNPDKGGHLVLWDLGLIIRFPPGSTILFPSALITHSTIPIQAHETRYVMIQYSSGGLFRWRNNRFQSDKSFLEHATAEEHAEREASRLSRWKLGLQKFTRWADVCRGDWKGTARTEAGLDEVSDLSDLEESPETTYPFKRVRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGV9</accession>
    <name>A0ABQ8VGV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_326910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050680">
        <property type="entry name" value="YpeA/RimI_acetyltransf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43420">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43420:SF12">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="56"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4493333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="25671" checksum="8A2EE02F2FCBB76F" modified="2025-10-08" version="1">MVEYTYNVVPIPFSPLPQSHVDKHASLRLLALRTNPECFLSTLEDESRLSPEQWRGRIDTEDRVTFIAVASEIPKYAPFDAPLDPTSSSSSSSLADTSGPSTLLDDDTAKWVGLVTVLTPEFLQKRWDDLPRKFRKFAMRSGKPAHVLVSMWVHPEHRHKGLGRLLISQAVDWVKNRVEKSSVEDKRGDVVLEVFEQNTGAIVLYRAMGFEDIEEVPPSIWMGRKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHL8</accession>
    <name>A0ABQ8VHL8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_305413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="215" mass="22138" checksum="CC53E052EF29727D" modified="2025-10-08" version="1">MPLPTKTSIVPRTGASGIPSSGLRSTTAAVTSKISHPSTSTSVRPLSRPVSQTATSNSRTTLTRPVPRTASRTAVSSRVGESTRPVHTATTIVRGNSTTSTTVASRSRARSNTTTNASSVVGVVAGLKRPASSAAASGKTTVRSVVTSNSTTTVATLKRPTTLVRSKSTNTATSAIKPARITDVVAQASELGGDIVRLDLQESLTDLGDDFMFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI57</accession>
    <name>A0ABQ8VI57_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_919047</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4495333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="301" mass="33942" checksum="2EF040003F04EDA6" modified="2025-10-08" version="1">MSPRPEVYIPGHVWDSQNPSERYASVGDLCAHIGDKLPLHLAKWIARDVLRGLANLHESRGKAHGDLSQDCILVSPQDMKMLISQFYNVDAQSQHTMPQSSEMSHTETHPIPSNMDTVVVPVAPSSTLALKPIVFRLCYPEISDRPRHHPFCDSFGMRPPEALLDAPQGISADIWTLACVLYELITGESLIDPFFQTLELGLTPEESHLIQIIEICGEFPRDVAKSGTNGCKWFHDDGTIRLETTYYPVTLKDILHSRIEPSEITHTADMLRSMLRLRPQERAKAVDPLNHPWFHDVDERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIA7</accession>
    <name>A0ABQ8VIA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_762610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040015">
        <property type="entry name" value="UBL3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039540">
        <property type="entry name" value="UBL3-like_ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13881">
        <property type="entry name" value="Rad60-SLD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="44"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="121" mass="13447" checksum="56AD16A8DE2C1784" modified="2025-10-08" version="1">MGDNPDIEAGIEAQDGNGEGTTPADTADIPAEEQIQAIPQALIVSVCFLMISGKRRVMTFEPETTVGRVKELVWNTWPSDWQEERPSTPSHLRILHLGKVLQDEDTLEGEIFIISYVNCTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIB7</accession>
    <name>A0ABQ8VIB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Meiotically up-regulated gene 190 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_918822</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF2">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="185"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="391"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="610"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="584"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="639"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="965"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="584"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="974"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4495380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1068" mass="119269" checksum="9944D6A1546BC9A0" modified="2025-10-08" version="1">MPTPEKKESPQRDSDGERSGNSKAMANEREVTDPITHFPVTIHDNTSIELEQIPPSRSDSKATEDMTTEETDQQRHTEMERVVWEETNKGWWEEPNHNRTRTALVVAISVSIGGYTTLVISKILPRIFARSTSGEGFGILDIYIGVVAYTLLAIAAGFVVLRYETKENDNNQQEKPWTKPSAQESPESAVWLNSFLDTLWPIVNPALFTAVSDMLEDSLQASLPKMIHAVRVADIGQGSEPLRILGIRWLDGADATQARPGMAAEEGDFVNFEVAVAYRATSSSSSLKGRSANLHLLMQFWLTGGIVLPVWVDITGIISTARVRIHLTPNPPFLSLMTLTLMGQPKVKLTATPLAKNFLNVMDMPGLSGWLQKSIDAAISEYVAPHSLSVDLKTVLMGREKMDTEARGVVWITVKSATGFKNGDGIEIWKSENGRKGDVYVTASWGKWGKPLWSTRSVDQIIQNEAHPIWEESTALLVSPSELNAQEKLKLQLWDSDRFTADDNLGTIELPLFDIMNTSETCNRIGHRQDRFLAEDGRSHWPGSLTWSVGYFSKTTLEEHMANKEGENVQDLKSDIEEEAKAKLREAETRKHSEKASEVEQQKKQDLREKTEEIVSGTPPTREWPAGILSVRIEQITGVEVDNPRQSGSKGTKNGEDGVEEEEGDDMPSPYCTIIINHAKVYKTRTKMKANNPYYDAGTERFIKSWSTTVVMIAVRDARMHEVDPLIGVVVLPLQQLFVKRGRSQITDTFPLVGGIGYGRLKCSLVFRSVQIQPSSEYFPKASLGWDVGTLEVKSETMRVSGSFPDDLKSARVLLRTLYGRDKALPNSLHDGWHQKKDRPVRLAVKNRFASCLLIQFRKTALGPDKTPAFGTLWLKDLPDLEEVTVRISVRRNEGNAMVRGRFNASDDIGEKVGELEMQVRFWPGLSGYHHWLADQDPSLADVMEVLDAAEESEEVSKEMLYEEGLDSDTELMSSSSSSSSSSPSSSSSDESSDVKGGRVKNVKTAVKDYNRRKGDLHRKHRGLMQWGAARKVAWIGRSTENEAKKFKQKLAGKLKHEQRDGGMEKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJU0</accession>
    <name>A0ABQ8VJU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_825425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="259" mass="28086" checksum="590FF511CD9E592B" modified="2025-10-08" version="1">MDPPDSLEKIFQRVEEESQRRAEVENGVLAVPEDKNLAEEIAKPLPIDVQRLSSLKSRRRGSVSITRFGQLADDTSPKEPPANSPPTTPTTIITALAAQSPFYQSQLLNNSHESIGSHASDNDGFHAEDDNHVTQVHRIAARQTLSRAVGSFLPRRLSRARSRPVIEDSDGTLVIGVSVQAATATVEESSPAESHLPSTTVTVGASLAPKLHSKESMSSLKSTSSNSNWASNNTWVSKAKDFTKKLRRKSGQPLTQSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJV0</accession>
    <name>A0ABQ8VJV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_254474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="585" mass="66650" checksum="BABA4823E8BCF37D" modified="2025-10-08" version="1">MIYLLYSHDTELFPMQRSRRLASVSSSSLETLSSLGYTSTLESVASTFTGPGSLTGKALLNFGKFTLKGFEQLIISRRLLAIGAHFPHHNADRIVGLPAMYADLLELSRIQLYPNSTRTRALQLLLGQIASRSTAHLMKALLIWPVVEVKLLISELLQCFDPLSIFNLVENNLPHALVSSYQQHLSQWEDHSLAPIVDFLQDLASASEQGWSIICDCGCLDFLLHLYLSDFKDLARSFNKSSVSATCTSFLLAAMANESAYRAFQSHALCSLWALWPMLALKTPDQTRCSQRRQVWATMGMTEIRWRISSIFDTLVLEWDSSSLTKLRVTLNEPSLFDLLIDLLEFSGSPQLDDEISFRALRSLHRLWTRILTTEANWGLEKYIEETPHDYARDIFIRFIRQLHLLSARAPESDAFFDPCHERCQAKGCPLELDAVIHIVHRLSRASRKNHILRRWLIEGDIVRLLDSTFSRLSELGALSLDVNVTDGGNYSSDNSVSGPRYRTLLLSLAWRLFNEKSQGDGNGFIPEYQSSASWFFSKQNPPPDWDDLSFPMQHHDNWADDLMSASVYHRKEHEHKDCVYSWIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK14</accession>
    <name>A0ABQ8VK14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_829618</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251:SF1">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="G-patch" evidence="7">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="14"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="277"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="44970" checksum="2BC2606120EDA378" modified="2025-10-08" version="1">MSASTIARWNAIALTRSDEPTPMKRKRDEDSDDDVLIVSRSPSPTSDAMDVDQDNINKYDEYVRRPAREVITVETPLKASNKGFAMLAKLGWVEGQPLGISGEGRVDPIPFQMKADSTGLGKVRQDVEMIETTVSQRRGLDSERQQKETEDQRRAREDAVARKSAVAEEISDVLKAFYCSLCDKQFKNVAQYDEHTNSYAHHHKARFKDMQASSRIKPQEEIEKRKEKEQKREEKQLRKIAAASGVKMAKTTLPPSGAPVLAPVANVTSGFQPSGWASVSGSGDSTLSSSSGGFKKAGWASVGPSSSPETLAPVSDSVTTTSSGGLKKAGWTTVGSTFPSTAQAVPPASASSGSWKIVTPSSGSSLDASSLPSNVPTPSAASSTAVEPVSQPAPQHPPSKSHLSRVGWQQFQKKNKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKX3</accession>
    <name>A0ABQ8VKX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_824507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="180"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="615"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="277"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="879" mass="98578" checksum="2054E9498120CAE9" modified="2025-10-08" version="1">MSSQTSSPTSSPPHSRPGTSIAPSTISTAASSPPPTDSNMVHEGELKEEDALENRSNSISMDETDVDARYERLNYVLEKSAIFSKLLKQSMDNANSKMFDQLDASTSKVKPGKKQTRRRKGRKRAIVESEEEEEEEESLVSKRRKISETSEDASQVTRQPSLITGATLKSYQLEGLQWMASLHTNGISGILADEMGLGKTLQTIAFSAHLRELGVAMPFLIVCPLSVLHNWIDEYAKFAPEIPVCMYHGTPAERATLRREVLRSDLFPIKKTHGIADDSKHPVKPGRGRGRGRGVTRKSAASKSKKMEKDIEEVMTPEETKRALKFPVVVTTYEMIIKDRAHLAGYNWGYIVVDEGHRLKNLDCTLTREIKKYPSASRMILTGTPLHNNLAELWSLLNFVLPDIFNDVDSFQSWFNVPTMQTSLGNDRTAHIIESLHAILKPFLLRRLKSDVETSLPPKKEYVLYAPLSITQREAYDKVLDGTLRAYLMQSKEENKGADEVLPEVDGPRKLRRQTNKGRPSYLVEEDDDVYFKNLETGENERQQAEREADLTQLRETHRRDLARKKVNNMKLQNTVMQLRKVCSHPFLFDWPVDPTTLQPILNDELVAASGKMMVLDRLLTELFKRKHKVLLFSQFTTMLDIIEDWARELKGWIICRIDGSSSPVERREQMSAFQTGGDSPGAPHLFLLSTRAGGLGINLVAADTVIFYDQDWNPQMDAQAQDRAHRIGQTKPVLIYRLVSAHTIETKIMQRATEKRQLEALVIAKGKFRMPSAAAQRGGKSETIAEMAASLLRLEGEKIDVVPNTSEGKANVLTDEDLDSLLDRSPEVFTDRGKGWTSANPPGKSVVESSKKAAFAVYDAPVDEGNDALAMMLGEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL74</accession>
    <name>A0ABQ8VL74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_917801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="209" mass="23642" checksum="822175363A332A5E" modified="2025-10-08" version="1">MDVDNGSREAASEPFTVRFPNAGLPVGQGATFLDDFNDDRFADERETNLYYPFASRPEWETASFLLNSSLSMLEIDSYLQLELTKRNNLSFNTAQRLHDLTDLLPAVPCWKSKTMRTLPLYPSRTPVVLYYRDAVEVLQDLMKSPLICDALNFSPLQIFKDSRKLVRVYNSWLSGTRAWEMQSQLPEGATLLGTILSSDKTTVSVITGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLP3</accession>
    <name>A0ABQ8VLP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF427-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="entry name" value="Domain of unknown function (DUF427)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310:SF9">
        <property type="entry name" value="BLR5716 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="24"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="142"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="254" mass="29313" checksum="5D67A8252BEC5F1C" modified="2025-10-08" version="1">MSSASVSVPPDLTKIHIEDCLKRVRAFLGGFFIVDTRKAKLVWEHQWYPQYYFPNNELPSKFLDDDSKQSLPDGATKYDIVVGDKRAPEAVIVYGDSNGDLTGLFKIGYNSMERWFEEDEQVFVHPKDPYKRVDVLQSSRHVRVEVHGVEVANTHKPRLLFETNLPVRTYIPQTDCKLELLTASDLQTPCPYKGVASYYHVQTGPDKKAENVVWWYRNPNVECVAISGYYAFYDELVDIWIDGEKQSRPKTHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLX2</accession>
    <name>A0ABQ8VLX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-conjugating enzyme E2 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_822036</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="18853" checksum="D185FD9544066F9D" modified="2025-10-08" version="1">MSNPCKRRLIRDFKRLSSDPPGGISGSPCPDNIMLWNAVIFGPADTPFEDGTFKLVLTFDESYPNKPPTVKFLSRMFHPNVYANGELCLDILQNRWSPTYDVAAILTSIQSLLHDPNPNSPANAEAAQLYRENMKEYVRRVKATVEESWLDPGETENGDTEMASGASAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLY6</accession>
    <name>A0ABQ8VLY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_917433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="846"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="917"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="312"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="425"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="569"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="722"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="849"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="934"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="975" mass="112551" checksum="07DA72D92D3D03F4" modified="2025-10-08" version="1">MAQQKRGVFSANFEDDSDSEEPEYSKIRLVYTDPTDELRNEVTSLRAQLLHVTSHQNSVAQAKSNAEKLSLKLTIAKSQLETKNVLIHEYKKRLNLTLGQFDSEVSSAVAGVIHNLKQVLVCLNTERTIKSQKSLEKEEDNSFLTSWSIRLLNEIQDLDHMYSELRKDYEQVRIEFIQAQESVLACIQTTEPDRHHHTLHQDVGDANLQFYQKYIVKLPELIRECPESSADVSSWFAWLEYFKDVKIKALTEINSRTERSSNVIVLKPGDIKAIKSILLLLLEDGQEQKSEKLQRVYEYEEVHALKPQKLLLNEKNKQLELVQERSLEIRRQDEDEAYQAKNNKIEKEIVAIRQKVHKLQLEKEELQSMLQVGEASSSNKLQNAMQEMKTQQEQQACFFEAQILALNRQRDLLEASLKQAWECKNSELKRNCEEFDSLKKEVEALETILGEKDQQLQSNEQHRLEIDSALQSYQSLEQVRATRYRELVKELTAAKQEVHLRQYSPQARLQEQQKAYQSFDARLNDMSRRKDLLEISLKEAWECKNQELEDSQRGCSILQEKIQTVQTILNQKEIQIQENELEISRLNASLQRKEEENDYEDSIETDHQMQVERLREDIKYLEDAVEQLEASRDSLEADLQSEEVKVRDREASLLQKEADHAIICKSLEDRLSAFRRDNQTKVSKTLLTDLQHAYELESTQLKDTQQKLIRANKKNVKVKDHIAGIEQKVAESQAQGEEMQRQIMQLEYELAQRRTQSKDIHSTVSILQDENLAKALRIKELLDLLEYHKIDHHSTLTGTSSTMQADQFRVSSSSSRATQLQLEPHTTIGAPSLALGQFAHSTASVTYQPSSSSSRNLLPISSPSVSTEMRSPMRSVPSTGEASIPLMQGIHFGGLNKSLRKAAVAAELRMTTKREYVLRPSKEMKPSSQLATSKLRHRNSLSRQHRKPSIYSKQSRVHMESEEEQDSDEENGKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM37</accession>
    <name>A0ABQ8VM37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-amino-3-carboxymuconate-6-semialdehyde decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_792285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF30">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="42"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="35763" checksum="3A45EF776E8507A1" modified="2025-10-08" version="1">MTLPPVITLEEHYASPSLLALQPLDELSYVLPKLINLDEERIIDMDAGAVTLQVLSHVATAVPSPDLARSTNDELYAAIQKHPKRFAAFAILPMADPSDAAAELSRATKDLHFVGALIDNHLDGRFYDDVFFWPVFERAQELDVPIYIHPTFPAENTKQQYQGNYPESTAYMLGIAGWGWHADTGLHILRLFASGLFDKFPRLKIIIGHMGELLPFQLDRIVPISERWGNQRGLRQVWRENIWVTTSGMFSLTPLACLLKMSPVKHVLFSIDYPFSKNETGKQFLEEIRKSGLVSEDDFEGIAYKNAEQLLKVKAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMM2</accession>
    <name>A0ABQ8VMM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase 2C-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_879634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="47629" checksum="80B3D46046D1BAF3" modified="2025-10-08" version="1">MRGSPREISLWRFGDGSWSYTLIPEPDISTELARQSGARTHGTTHCVSFQPNGLEENWNQDRYVVHEYTLPNGSVWKLRAIFDGHMGHDTVNHVAEHLSTKVQDRLNNAFPKLDPDTVSSLLAEVITAFDDSLLLDLLSGIPSKSQLSSLTEYEVQNIIGGDHRSKVLRSMQGTTVIIALTNPDNEDLWVASLGDSYAVLGIQSSYDDQRELMFLSSYHNGLNSREREQLIRGHPNEPEVLSRNRVLGGLAVTRALGDYPYKLPSIYTDRVFLHASQSRNQRELINSVSNRNKTPPYISNIPDVKYVDLKSKRLGNSPSGLNTNKQGNDTALRMCLLMCTDGLLDLYEDELETKEPLDIFQRCMDVACAVPTACETSTTSHCDNVALSVLRDALGGIDIERVSAMMTVEMQEKWMDDTTILFEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMQ2</accession>
    <name>A0ABQ8VMQ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Membrane anchor Opy2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_759024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="67332" checksum="2CAE7F5462EF58C3" modified="2025-10-08" version="1">MHINALLGGRDDCVNDCDVPSCSCATDQTCVFINKSCTQCAFYECQDNPQPSSTSSKGISAGAVAGAVVGSLVFLAIVFVLFFWYRRSPRFRSTAPTVEVKDVPASADDVLNRPDPMEKHHSSTSAPATELNTVRVYSSSSNTTIDLDPESSSNHTTGTNTQRTSVRSNPFEDNHSIQTTGTEGTNVIPIALVTPDSLHHSAGSSETETSRSPSPMRPARTPEVDLNLDHINVSHDSLKQIGNYPTSTRSDVSATSRNSYMSSASYSSDFLNEAPMIMTPNKGAVRQVLGVVKAEMVNAPGHSPTTAEGLKPSASTSKPAVRSPLAASSFGPADLNFDTASVSTSEEGGNPFSDRHSTRTTLASSPAASHTTFGEPSPAFNTGTDWAETGPRLPWSTGDDGSRPSSVSTQAGSVIDIANATRVNLGLSQLSSESGVLTPRTRTTMGKLVNPSTATTELDTFEEQQQRALAHAQAQAQAQGGVQSRRISASSAMSATADSILESFPFVPPSPISNRPARSPPISPLAQQAFNVSPPSPMSSQNFQATTFDSKLDSNVVQPTPNRKTLGLSTGSQLSTVSTGLGSFPFQIDTGNSRDSTAPSAFSGRQRASLDTLAITSDLSSFPLGFDRDSVTVPVPRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMT2</accession>
    <name>A0ABQ8VMT2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxalate decarboxylase/oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_182442</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045477565" evidence="2">
        <location>
            <begin position="19"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="3">
        <location>
            <begin position="105"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="3">
        <location>
            <begin position="284"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="442" mass="47964" checksum="9F10985E80102692" modified="2025-10-08" version="1">MRNILSLLFLTILSPAYGAALPSQDATSTLSPAAEPTPTVPYASTTPNAVLWGPASSNSVPKPFRGKTGGSVLGPDNIPIDLQNPDLFAPPSTDNGDVPNSKWPFSMSHMRLQTGGWARQQNTEMFPVATSMAAVDMRLEAGAIRELHWHSTAEWAYVLKGTTQVTSVDQDGRNFIATVRPGDLWYFPPGIPHSLQATNESAEGSEFLLVFPDGAFSDDGTFLLTDWLAHVPAEVIRKNFGITNSNAFSRIPSKQLYIFPAAPPADDAEDVSDPQGTVPQPFFFPFSQVAPTKLEGGSVKIADSTIFDVATKIAVAEVEVEVGGMREMHWHPTQDEWTFVLEGEARITIFAANSNARTFNFQAGDIGFIPASYGHYVENTGIGTLKYLEVFNSDRFQDISLNQWLALTPPALVKAHLGLDDETIALLKKVKPTVVGPPSSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN69</accession>
    <name>A0ABQ8VN69_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_821246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="26588" checksum="F88D7A6ADCD3B510" modified="2025-10-08" version="1">MEKYLTNTDLTSQNDTQDILGRAPGSARFKPYTILERKCGPKKKNSLLDLLPESGNPPSSSSVTKLLLKTLKEAANPIAHSDLYERTEHVVSMASGHQVSESRRNHRPYLQERSRKLAVQKETTNAAEQPQILSNVKVYIDGLLSGTTDIEMKRVVSRAGGQILYSASGATHILSSQSLSGSKTHRLLTKKTRTSVHVVRPEWVFDSIKAGKRRPERDYTILKNSSTLNVTMMMQKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPF9</accession>
    <name>A0ABQ8VPF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_761858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="89" mass="9837" checksum="D522946261F98FB8" modified="2025-10-08" version="1" fragment="single">CDTINLDGSSIPASVEKSTYTHAQKMRAAATFGFGRIHGLGMQAWHSSEITGKMLGNPSVSEIVSTYMLSLRRRKASYYFRTSSLLFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPP3</accession>
    <name>A0ABQ8VPP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_790637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="713" mass="80296" checksum="DB2434C72785E182" modified="2025-10-08" version="1">MASSSSQSPVSPVEDQHGEHIPVRTKRRYGASCELCRRRKRKCPGRDSNGNSLCTHCGEVGVKCVFPPNGSFLRARKAVATTNSSPALPEVDTLRAYIRHLADASDSERERMLNQWIDDHGSSGSKDAVRKLPHKLSGRSSRTDGVDFDEDEDEEPQLSLLRDAPSRGHRSFKKPKLWPDNSQNTSLQGDPEEEDGQSAEKSLQPESALRLSLKPATPDDSETTGEDELSVDRSIQSTTTLQANISAWVDRWIGNSFPTGVTAEGPNPVDRKLLFDNYFCWQGPRNGIVHRAIFERALEENDSKHIPILRDRVHEYAAKAHYLLAAELSRPSSIPTYSTGLMLLASHDAARGMYAQAWNLSSTAIAMMMDLGCHLDKAPFTSIDRNDPQREQRIFIQRQMRSRVFWSAFIWDKLISLALNRTPLLNSEEHAPPFPEPTSSSDLWIPVLCADSPPSLFSYAPQPSHEMKCFYETCRANQVMLLNHLPSSTQVFYSLQFLDQIHRHLYRTQKLRSTQTREFVANMRERMLQWQEEACPEVMLDLRAPLEVSPPPHIMQLNLLVRLMWILLYRPFFQSSAGLDQSPSVLEAIPTCERAAIEINHIFTMYDRYYPLSRASYIVIFAGFLQATVDLALADREKSVSGPTLSRLALAGRVLSGGSANIPGIRTAECARNECNIVLFGLYPWTVKRLAEYFMFAVIIKSTIQCDSSGRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPQ6</accession>
    <name>A0ABQ8VPQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-NAD kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_818938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="628"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="725"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="629"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="654"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="824"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="94853" checksum="257512244DAE3D88" modified="2025-10-08" version="1">MSLSPEIETFSTPPTTPGFAAFQDASIRPSLSRKGSRPSSLQLAHQGWNPDIVVEESSPVLTRKPENGQSITSSMSRDQTATPTSSTSTRASSTLPSIPSSSSSTTHLANGHTHRPLDSPCFVHSQLDKGASLSDWLRNKQNGILNNGSSDVGVSKSLQDSSPTSTSGMSSASSLMSSIDDEDEFGGNLTKQLAETAVGVREMSKQLGRARIRSNIQNILIITKARDNRLIKLTRQLALYLMLKPRPAQKRGLVVYVDNQLRHSRRFDAAGIERDHPELFIPFPHRRTSSSASLASISSASLSREDFTIKDEGQLRYWTSAMCNHSPHLFDFVITLGGDGTVLFTSWLFQRIVPPVLPFALGSLGFLTNFDFADHQAVMDSAIDSGIRVNLRMRFTCTVYRAVTNEFKGRKAVKKGETGEILMRNIEQDGWEALEGGWSGSFTAPENGKVGRDKEIMCFTTRPVETFEVLNDLVVDRGPSPYVSLLELFGDEHHMTTVQADGLTVSTPTGSTAYSLSAGGSLVHPEIPALLITPICPHTLSFRPMLLPDSMELRICVPYNSRSTAWASFDGRGRVELKQGDHIKVTASKYPFPTVCADKQSTDWFHAISRTLKWNERERQKSFVVVEEGPEKVKKQKKVEKTGRDGTPKPTQVEEAESLDDEEEDEVSDEEEEDKFDIDDSSPEAAAAASVISGQVTNVLSKRDQAVGHEKANELVAEEQLHKALSLSGLKPRRHTPRSRSVSPSGLRSGIDSPSRYAGLPPHPPVSVPRHVEFAPESSDESYGRNGARDELFAHRKASAKSRIPKEREDVKTPTASNLVYPRNRSRGRAHSRTRSGEYVGHRAFAVWGQDESDSNASDSDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQC7</accession>
    <name>A0ABQ8VQC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_138894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1399" mass="155924" checksum="7ED4DDD28B2C20A6" modified="2025-10-08" version="1">MGIFEEARQEEALQAHIRRLLYDYAKEHLTTSYVEFTERAVAELLSQSLHEIPIADSTSIRLPEEPFNVLTRLYALNDLKPYNEQGTRSTDVMKYLKTFLSTLKQGTKLRSERAVEIDDCYILEERFVPMLSRRARRETLRPGSNDFRKSLKTPYGAFMKSSEVGIKPVEVQVLKEPAVKLEKVLNVTWSLPHDTGIEVRDFLKSMATLAYPGPSYKNQYLDPSSRPDSPPLQLGPGSSLFYESGDGFVPFEPIFSRAQRPGFGRAKPKERNEGPVMQPIAKSHLFGNRKTKDKGKDVDAGIDTKDLFALGLPPPRSISQVVPRLNTVPVDEDEGFDLLKENMKIVNGWETYHTSSPAPASQASGASSLSSVTTPRSSQEVDELNLNLAISSPNTDLSPIKLLKESRMDLPVMPRSKRNILSARGSTATKTKKIGAKQSYAAFLLETLNKRNNLLSKRDEPLPPIFEQDKMQEALPAPLSSLRNDLRSSPILDFDEPDVNPLIDKTPMKAEAASIVKENFDDAASMAGQVGSTVAVDSLAAGMRGTDNTADIDNFESELHAIFKDVQREDPLGLIMREKLDAMRNGKEMLMEVPPLPAPNKHSPNDDVLFPASGLRQYMVPSGTGANRGREKNKVYQFLRKAKGTASATLVLSWVPFAVTTSLPTQEEILAVHDFYDKNTSILNGFDRLGMTKEQGLARVDEMSERAKGAYRVTENDNVNHNSDAESRAERIWAEWSHHGDQITSSVLHSRPDVGKIDIVLSREERRRSKGPGSSKVVERVADDCENGETSQLLDDPEEEECGVDPAERTGAVAGDFQEMAAVAEYHSCSSIVSAPANLNTQHSLNFTSDAAPPSQVYDAELFSRAETDFGIPSFLEESDIAIHTHDRAIHADDQPLESFATVQVLDEYPHTNQYGYEFVEEFGSDSDKENQDPSNLKAIAQVTDLEWDRSDTPLLLHGQRERPDYQQDEDDRIRLAKRPRLYWEGDDRYQSRDYRYDDGGPEVEDSGIGLLDYLSCSPARAVNMPPNATQDDQAYIVNRVLFEDNHPTDGVNDERIQNHFDLEDDPISTQLQNSDFVPLAFDSQPVPDAQSQRPWPPSAPQSPPRGSFLKKAAPFIIPFHDHSVGIAEFARLRARKIRTPPPAPEPPKPTTADSDSFEEVMASKIAPEAIFDKNTLRLPGADRTFRTTAHWYMASMNLIQKQALVRSLRSGICGVGLVEREMLTGVDLIIDPHTAVIFTNLLALPSEVDVLINTICEQSWRYAHLLVVFEAFVPSMSFKPDSAASAKESLSAYSPPVLKAMRKFRRDVSLAEACGNKREGCQVMTAFAETVQDAAVFARTFGDKAERRGDSATGLWGNRAWLDDGVGEVSIDLNLFTEILLLISIEYRTKKTLLLRME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR29</accession>
    <name>A0ABQ8VR29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1746 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_819164</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038967">
        <property type="entry name" value="Dsc4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013715">
        <property type="entry name" value="DUF1746"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39405">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39405:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08508">
        <property type="entry name" value="DUF1746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1746" evidence="3">
        <location>
            <begin position="16"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="29569" checksum="AECE05AD6DDD5233" modified="2025-10-08" version="1">MPRRYHVQRKHIIQALDALLYQLFCFSFYLSPSLFTMFLRLSAQLVCATTRELSPTMSLGSFFFFPLFSNSFSVWNHATVGPTEGRAVVLDFVGLAYAPTKFQLLFVDFSIIFMQVLLTIISFEMHTSDSSTADSNDYLLPAPTSPIPPPLLPASISLETTFANQKAFETPNNEPQYILDIRVSSIFARLRNTPAMSRTSNSQDTLIPFPNTTSWPIPITMLMRTAGRRRQMATERATAPSRDTGEDRDSRTVPGGMNTENLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR36</accession>
    <name>A0ABQ8VR36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_864385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="22106" checksum="4B8F27917C96B879" modified="2025-10-08" version="1">MSRSDSSDRSHEHESLHAPEWKYFQRISESTFQLRLIEGELVEVSAQQFGAYLDHSIDIKKHRYKAGDSPIGYTDFAEAFNAEEYDRKLAYFDPNYEGEGRVPIVDFDTKSPSKDLFDLMPYQCYAPGALTRPGYVEIPQKEYEELRTSAIAYTKTSLKGRMKAEEMKERKKLAEAAQRQKKKGGLPYIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRS4</accession>
    <name>A0ABQ8VRS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_79610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="252" mass="27681" checksum="B17D7D0F1431D542" modified="2025-10-08" version="1">MHELSFVSVLNILGYCPNVQNVTVTHLRTFGATSARVKPEITRVCNAQSLSIDFGIRSFDGLRGNLGATDLENLLKSITMPRLTHLAILDTFSNNENFVEPLRDMLERSMCSVTHVRIRGAQFNKDRMHRLFDSCLSLVTNMEFEETSDAAYECFFDGMTAHHQEKDTAKNATSSCNAEVGGRISTGVTQTQVEGDSVPNTNNGAEVGVKAAVAPTQEDQSSPSFLPNLTDLSLIIIPQTEMTEAHSCHVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSN9</accession>
    <name>A0ABQ8VSN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_815588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="846"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="855"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="931" mass="105381" checksum="0AB6CD51BC04ECDF" modified="2025-10-08" version="1">MPSSEDAHARYLSEYLETFWTEMKPDRGLISLRSLAVLLQHNPDLQQLVQKAYEEGNSSILKDYDFPHHPRGMVYYREELCEIFNRLETIREPLEKVVDGTATYNSLAWNLRGDSASSTDVVEHIRKLSIPCKRRSSEPLLVLHETGRFQSEPELNERLDHIFTPEKNTFLVNSSGTGKTRLLYEGLCKHWGLFFTAAVDTFGLGSVDVQSVVNQRLPYDRNFTAVLNDEDATSDSGPVLANIALAYRRFSETLLARLLVFKLYIEIVAKGEFQEVHKRRWLLAQLQPYFTNGSDVFAVLQTTIRNSRVTDALLIDCITQCIEDIMNLFRRHSPGSHFFVVLDEANAASERHGFAFRGVHGPHPVLKEIIKTWQSHLHTMSSTMVVAGTWIPNVHFQEDNWKEWRWTSSTGAFDKIEDQRAYILKYIPRDFASSASGQHLLHRMWVWLRGRHRMTAAFITIVLVDGFRSPHYLLNRYIQMFTDFWPSDGGEFIRAELPRSCSELDGIPMGQLERIKPLRVNMQHLLLKHLIADYRFTPPLFHEIGWVTTAFGRFSDDAMTCVAVDESLVLIAVAQWLLEESYLAPDLDRFISSRSFAAEPLSYDMDYVAFAVALCFKRPRVVSDVLSFSTITPPNWASQRAHLVALRREGENVTEDTIEYSPEKPSQLVYYTSISSAVLNWLKDSHGVPFCMHIREATATLYFILELEDSARICLSLRGISNSEDEDHGESAAIRTAVNEMTPLGLLKEGDSLDEATLTAAFGAIPQRSLDIGSIGLLRTLVSLRDKVRIQGVPFDALDKYPVATLNITTLRDALKDISQKDVFSSIVTSVVGDLKRKAPPETFVSRTKLRLSDPTTEASSSTSVAPTPSRTKAIGGRKLRSADQPQTSHPKSQGIKNRKPSAPKKASRKVETALSEPANSRYNLRPRKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSY3</accession>
    <name>A0ABQ8VSY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11655">
        <property type="entry name" value="rap1_myb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="588" mass="65603" checksum="F4785BAB49508880" modified="2025-10-08" version="1">MNGFPPFSRDSTLQPPQHNGQHGNYSTNFSSTSSTPFTEFSPQHMNVNVANGNSQMRLPTSQEQSQPHFNSIASPWGISQQTQQHIAPMLSHPQQSNNHWNNTIPAQAQFMNGMNAVMNGMSNMPMNMNMPALNMSLFQQQMLHDALALSTPVAGADDERLIIDTLVDARARKDNYKNALNSLHGKNGHSATLWKDFYLEWKDKIDPHVSLSLKRKGIPDPLPIVKVAKKPTPASFKHEPSPPPPSPVHALKPKGHFPKASSSRSAVSSSPNALPKLPSIKSGNHRSTINSITAHHPSYNSRLPPPNSEITIPDAPSCSPSPPDKVVPHSRGNKFTKEDKEFFIKFIQWRLRCDQSLTRNQLCEQLAEKAPHHSLQSWAAHWSNNHDLPDKILAAAYGEADTNEEDTEDESSGEEEVQKSRPRKSIYKESSSEGDEQDADDDLDQEKDQDEDFILPSFDESAMGMAGGSFTDADFALTARYIASFNGFSNKTHSSKWVPWSQRYPQRSHKSWAEFYRRNEQSLVTLARKIKNAGAARGLSPKREESENATLADLVPDANGPPKAKRKYTADDQEQNDDNNRSKTSKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSZ7</accession>
    <name>A0ABQ8VSZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatase 2C-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_754309</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF589">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="5">
        <location>
            <begin position="44"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="43462" checksum="DB129D04DEC907DA" modified="2025-10-08" version="1">MAFRLLQRSPKYAFLNSLNRHFSDYIRYSTPSGVIRLPLASPKVIGAATSRGNRSHQEDFYAFAALSLDPEELQVSLKKSLDIEWDPNLVGDVFSKQAVFVGIYDGHGGPAVSGYLHQELHGLFESVHPSMIPELFAWIKELGGYFKRYKGGPLTPWIIEQNHPVVKFNLEARAAAAFFEVDRQLSTDNMSQTCGATASVAILQSLDAPATPFFSANRLALTVAHCGDTRVLLCSTDGGRVFPMTENHHADARGESIRLRRMMGSSLITDSYGESRWMGALDNTRGLGDLRFKKFGVTAEPEVRTKLLEAGGEWAYIVLVSDGVSSTLSDDEIVDLARDAPDPKAAADRILAFVQELGGEDNRTAIVLPLSGWGKIRGPDKTKELREYRRRQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTC2</accession>
    <name>A0ABQ8VTC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_754421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="138" mass="14470" checksum="952D81400EDD9321" modified="2025-10-08" version="1">MLSRSSCSLLTQSKNNVFKILSRAASTSTSAPITSNHIATPTPAGSTPSTPVIGTQAPNYPSTWSANQRTRPTSGSGPRFEQTAMELQPNPLSAMAMIAEEPIRLVEGRKAVCDGGGGPLGHPKIYINLDRPGPRPCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTF5</accession>
    <name>A0ABQ8VTF5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_915385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="159" mass="17497" checksum="1D5193BD1C271691" modified="2025-10-08" version="1">MTSVILPQMLSTSLPQSLEIDSKAMKPYHELQCLEDAVQAFTQVLVQSGRSTVRLHCSVPTWSAESNLCLDLHDLNHLRSKSLMLIHDLVNSLRSSGIFATYYLAPAHSPMCLVCASSPGFDASRINTRAVTMLQNAKLDIGEHVLLADLERCSSLIIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTR8</accession>
    <name>A0ABQ8VTR8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="5">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_606790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF105">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="34"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18080" checksum="84D596DFC35A89C3" modified="2025-10-08" version="1">MPPTHTMPESDEDAREAVEKVFEVRPCLWQLKAARTILGGQDTLTIAPTGSGKTLSYWLALVFVPEGTIVVVTPLKDLGSQFENELKQKGFCALNVTGNITTNNLHKDIASLKYRVVIFSPESIVNDGRFDDLLSNRKFMRISEAWAAPIYNGATCAIPIRVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUM1</accession>
    <name>A0ABQ8VUM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_573434</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="373"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="680"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="728"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="880" mass="98016" checksum="9B3350CE93A6907C" modified="2025-10-08" version="1">MPVAKYRPEQEYGEHVKFVVKEKKVKCNGQEPCAYCVSSGKICSFKDINDNAASARQQSNSVELRLAKVEETILKLLPMAQAFEAWLRANNQISTPGLPFRIDPDSTTSNIQSPISRSPPVEDRPSTSTSYRASNAIKDLCVNDVSESSYTPRYDHDLMESSSSYGPEKWSDRYSHLSKDSYGQLRYTGGAASFMLVDALASLQNQAAIDASSNSTLSAKTDIQLPFFAPDKTFRKQPALPRPDDIGYPSHELADELVATYFANIHHTFPILHQQTFVDQYMKAMEQKAKGKPSREHTFLSSLFAVFACGACLIEKGRPKSGQGEGNEFRGFDFYEKAQLLFWMGTGSSQIEHVQCLSIMAICNATWNTLAQSWINVGGAVRRAQDLGLHLSGRHLPLTHFEREYRRRVWWCVYGLDRVLSISLGRPSGTHEDDYDVELPSELDDAQLAALREGTFPSNSVPSKKSYMIGFVALLRIYVIAGKIMRFVQSAKVEDARSEKMHESVMDLDSELDNWQHNLPPEVKYAANDTSNPKMFTLCLIAHFVYNSAKINLHRPFIPDRLTSSSDHSSWTRCLAAARSCIRIGEITQEMLPASHHLAFAVQYITLSAVLLLRSTAYVNQPDLFSTIISDAETAVKSLEGMEGIFPASKRCKEIVASLLSVVRVKLYGGPSAIEALQATQRMQEEPQQESLSAGVKRKRSVDPGPIASSSRQRLDDRGWTSAGYDTSLDRNTDEERYEQQQFSNLMRTSSIRTPMSNDISLPPTPSDTVPGHALSNFRGDPALTLNSGKQALPSFEQLVKSQGYTELPTQISLDINAWSTGRNHSIDEYSGYDFLGEDLFALLGSVVKPLEQPSPHTFEENAQALWQAFHGKPDAPFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV95</accession>
    <name>A0ABQ8VV95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_752183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="25138" checksum="CE7D27A30AA9D572" modified="2025-10-08" version="1">MDGDYISQSSYQLTTYLRIASVSIALYDFLETAPSTCRYIREQWNAPHMTKLFTALYLSRFTSIATLALSNVGYFYSHFTERSCSHYYLIPSIFKVIQSTVSQIILGLRAFNLSRRSRLVGGSLLVLLIAATALEGLTNLYHRTEFLFEDLKPDQNNSCRGVFQIIHLGAWIYYVVAIIYDLTTSTICMVYLNKYKTASNSLYVPIHLSSMVVLIELALSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVD8</accession>
    <name>A0ABQ8VVD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_751941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901">
        <property type="entry name" value="2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901:SF38">
        <property type="entry name" value="PSEUDOURIDINE-5'-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="257" mass="28839" checksum="356D84ECFBFE7A3B" modified="2025-10-08" version="1">MPFSKGIEYVLFDMDGLMIDSEKIYTDVTNEILAKYGKEMTWDIKAGCMGKPEKEAALYLLSFFPDISLRLEDYLTQRNQHYKKLYLAWPTVPLLPGVRKLVLHLKKHNIPIAVATGSRRRNYEMKTSHLSEVFGCFEGNVVCGDDPRSGMRSKPDPDIFLVAAKETLGRDVGPLKGEDEKGDEVTDAQRIERGKGLVLEDGLPGMQAGKRAGMAVVWVPDANLLDVNYSGDEKADQILKSLEEFVPEEWGLPPYDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVG9</accession>
    <name>A0ABQ8VVG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-trimethyl-L-lysine(9) demethylase</fullName>
            <ecNumber evidence="2">1.14.11.66</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_811207</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:60200"/>
            <dbReference type="Rhea" id="RHEA-COMP:15538"/>
            <dbReference type="Rhea" id="RHEA-COMP:15542"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.66"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the JHDM3 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.66" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF7">
        <property type="entry name" value="[HISTONE H3]-TRIMETHYL-L-LYSINE(9) DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="8">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="9">
        <location>
            <begin position="306"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="606"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="541"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="859"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1071"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="881"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1144" mass="126769" checksum="7AD491A8B8BF42BD" modified="2025-10-08" version="1">MDFSSPTPSLTPSIGSPPFIPVQPDHFYRLDDSSGLPSSPRSLDGTTWYEPEDDRLASRGIPVFRPTMEEFRDFEAYMNMVECWGKYSGIVKVIPPKEWSDALPSVKEQLSSVQIKAPIEQLMLGQTGLFRQQNMEKRRTMSVREWAEFCSQPEYRAPSVDEVGIHARTTVKPKTRKTRKSKVTAKDEASDLDLANQVVIKEEPVDSLTHDHVLLSHSATPVADDIKPKVKNNRRQQAKLTEVQKLERDASFLDSFDPALDWLPFSMSPEDYTPEFCAKLERHYWRNLGLGKAPWYGADTQGSLFTHETEEWNVAHLESELSRLLPSSDRGLPGVNTPYLYWGMWRATFAWHVEDMDLFSINYIHFGAPKFWYAMPQGRAAALEQTMRSYFPKDTSQCPEFLRHKSFLASPTLLARSACRPNTVVQHAGEFIITYPRGYHAGFNLGLNCAESVNFALKSWVELGKVAKACKCVPDSVVIDVGQLIADRAREKETAETHPSDILPSSLRAKPYARKSPTRAPSILVKEQEIYVSIPPLAKNKRKATSSANHTPAAKRSRKSKPTTITLPPIASSHTVVTQPFPKLSIKLKLGPRPVPEVFPCCLCVSMSNEGLLHVHDPPFDRKEALEACSNPSVWMAHEQCANIIPETWVDAVEKVSGEREKMVFGVDGIVKDRWNLKCSACTRMQPKAHGAPIQCTRGKCLKAFHVSCACEGKDNNIVFNVLRESEKEVVLLDAVSPPNHKRVDVETHAVNGHDAMAPNKDPPSPNVLKVIKKLEVQVLCSQHNPAVAAAKRASKQDRIKADLLALPSMSRIKLRVSAGVFEVSLIRVIEEIGSVEVVWDRGSKREFKWGSVVFGNTDGPILQKPSEPAPDPPPMGASLTPYSTSSTPQVTASHLPPVEATSTSPSYSTTSQYPYAAYNLYDYGKYLPQPSHASHGAPNMGASSTNHVSGPSFTASYTHLAQSHYLQSAWQQQYQQLNLTQQYRPSAVYIAPQLSTQSGSLLSALNQTPSTSVSPTALNTPTPIPTPILTPSYNSISSSVNVMPNCIHPTPIRTTGSISNTIQTSAPTLPSPNMQDPPSVTLPHAQSSSIAYTPPQSHMTHETSTQAPVFDFDALKSLRPEQLVQLVRDNAQFRDIFQSAFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXA8</accession>
    <name>A0ABQ8VXA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_750166</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="9">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="10">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="446" mass="50011" checksum="6F0ED0098760F185" modified="2025-10-08" version="1">MREIVHLQTGQCGNQIGAKFWEVVSDEHGIEPDGQYKGNNDLQLERISVYYTETGANKYVPRAVLVDLEPGTMDSVRSGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAEATDCLQGFQITHSLGGGTGAGMGTLLISKIREEYPDRMMCTYSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICFRTLKLSTPTYGDLNHLVSLVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMTGFAPLTARGSQQYRAVTVPELTQQMFDAKNMMAASDPRHGRYLTVAAVFRGKVSMKEVEEQMQNVQNKNSAYFVEWIPNNVLSAQCEVAPRGLKMAVTFLGNSTAIQELFKRVSDQFTAMFKRKAFLHWYTQEGMDEMEFTEAESNMQDLVAEYQQYQDATVEEEGEYEEELQPEEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXJ5</accession>
    <name>A0ABQ8VXJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">beta-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_913664</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF2">
        <property type="entry name" value="BETA-GLUCOSIDASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046222068" description="beta-glucosidase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="11">
        <location>
            <begin position="669"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="749" mass="79862" checksum="DF36151CE682BEB7" modified="2025-10-08" version="1">MISSRAVVLLVFCLSSIPKSLGFVERSWAESIALANETVNLMTLDEKIGMVRGVGQFSSRCVGNISPPSRSFIVSGTNITIPPLCFNDGPAGIRLGGSNVTGFPPAINVAATFNRDLMYSRGVAIGEEFRGKGIHVYLGPAVDIMRNPKAGRAWEGFGPDPYLGGEGAYQTIMGVQSVGVSACTKHLGPYNQEHWRYGLNAEVDDRTFRELYWWPFMKSVEANVSALMCAYNEVNGTSSCHNAALIGDEGYLRTEGFQGFVVSDWGATHDTAADNANAGLDMEQPGDWILIGGGVYSGLEAAVDDGEVTEARLNQMVTRILTPWLRLGQDQGYPDINFNAQDPDGTDSLNLNVNVRTDAHTALVRQIGSASAVLLKNNRTTSDGTATGTTIRGLPLSKDIKTIAVVGQDAQQLNLDCGGGLNECNDGTMVIGWGSGSNNVEFTVPPIDAITDFAQGFATISSDITSNDLTGGPAVAEGKDLAIVFANAMSGELGFYNIVDGNEGDRNDLNLWWKGGSLIEDVAAVCNNTVVVIHSVGPVPMSSWNTHPNITAIIYAGAPGEQTGPSLVDVLWGAVNPSGRLPFSIDDDEASYGTSIVYGIDPFPVLDYTEGLFLDYRYMDSQGITPVYEFGYGLSYTTFAYSSLSIEASASSGSVSFILTNTGSFDGTEIPQLYLGFPSSAGEPDKVLRGFDNVFLASGAKETVTIDISQKEMSIWDVVSQEWVVPSGTFNVYIGASISDIRLTGSFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYK7</accession>
    <name>A0ABQ8VYK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_892984</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="140"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="441"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="456"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="529"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="591" mass="64152" checksum="52E41810DC3A64DC" modified="2025-10-08" version="1">MASNLLDAFLTTHSRAVRPLRPIPQSLWTSLDEHLSPGLWAVFKTHEEACAVLSLPPTTMSIAPALESDLEPFHKLSRFELHLPSAASNPTPSQLTLPCRPQMFHLQEARSEQFPLQESSSRGVAFPLSSNPPNPRTNFRLGDWICNSPKCAAHNFGRNLACIGCGSSRVVNSSTSLNYQPPLPPSTRTPLSPRFASSPNTPNFSSVISMMHNNQTYAPGPSSPSPAQPVNVLPVSQSKNGHPLLTPSGRAFAVGGRVQNISVDPLSPCIMYWPDNEAFPDPGQIRPNVIMGISPPILNTGNRGPIAHVRRVPPSFSNQATGFAKSFAKLASLVIIISFHAHPHAEGNGDSISAAVQAERIALLTSVLTQNHGPSAAQHPALTPLRAQVLRAHSVTPPQVRRQFVDVSPPQSRGPSSVVHRSQSQVELGSQYMINNQKAPPIYQTSGHRRPSPVYSTSPQPRRSLSQQQHLHHQLQIQQLQQQLQQQLQLHAPTPAPLLPSFLQDIVHSPTLSTSSTSSADLSFDEYDTSASPSRTSVTSRSRQTSVDSATMQLANIWKMDSKESRSISAFTLPNTIVGGSRKSSLEKLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ40</accession>
    <name>A0ABQ8VZ40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_805348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911">
        <property type="entry name" value="MODULATOR OF FTSH PROTEASE HFLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911:SF2">
        <property type="entry name" value="PROHIBITIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="2">
        <location>
            <begin position="249"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="567" mass="62114" checksum="F694CAFEED5C1426" modified="2025-10-08" version="1">MVKSINMSNYADGSTVVGDDSRDQQDFLKSKPKVNDGLLPNPLLPKKRVGNPFVNSIETELEERPFFVRIGKDGLIAALQKLDRQLAESGRPKLLSKKVPTDWIGSEITPGQLGLINHGGSPKILTRPGRYPGFPLRNWWARSFEGKKGLSDTVIEFLGLTVVQVSQNQAAVISDPQNHIFVIKNAGFVCFAIEGTYDVLSIVDQTHLSQSVKDKITKSTLGWTHEVTMKSKTNAQEVKEYVVATFLNIPANNCAILQRGDDLELLGAGQSVITNPSVTLRGLYTLGENQIEMPTKDIFTRDQVPVSLTIYLKWQLTEPLKLTTHGYNTPYDALRDKTQSILTQIVAHLDYSAMVKQRSIGPDNMEDGTDPSSAFLDALRTRAMDEMHEAALDYGIVLKDLAVIDRQFKGEIASTMDKLTTRALQAQVEAANVDRENSNKVKQEEGALSVARIKAQARNTQADSEAYSVVAAAKAQAQRTRIEAEAQAEATRLAAQADAEAIRIKAAADAQVSDEFAREMELRRMEVTKVRAYGAKTVFVPSDGPGSQMGSAMAMGMAAGMGADRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZE1</accession>
    <name>A0ABQ8VZE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="5 14">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_748149</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="5 14"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF0">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 14 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4501680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="417" mass="44479" checksum="DB2FE5C3F34F3F64" modified="2025-10-08" version="1">MSLSNKLSITDLDLKGKRVLIRVDFNVPLQDGKITNPARIVAALPTIKYALEHGASAVILMSHLGRPDGKVNEKYSLKPVAAELESLISKPVTFLKDCVGPEVENAVSSASLGSVILLENLRFHIEEEGSVKNKDGTKTKADAAKVTEFRDGLTKLGDVYVNDAFGTAHRAHSSMVGVKLPQRAAGFLVKKELEFFAKALEKPERPFLAILGGAKVSDKILLIENMLDKVNSLIICGGMAFTFKKTLENISIGNSLFDAPGSEKVKGLVEKAKKNNVKLVFPVDYITADKFDKDATTGTASETEGIPDGWMGLDAGPKSQELFRQTVLEAKTILWNGPPGVFEFPAFSAGSKSLLDANIEAASKGAVVIVGGGDTATLVAQHKSEDKLSHVSTGGGASLELLEGKILPGVAELSERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZM1</accession>
    <name>A0ABQ8VZM1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FACT complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_928929</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the FACT complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M24 family. SPT16 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.210">
        <property type="entry name" value="FACT complex subunit Spt16p/Cdc68p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029148">
        <property type="entry name" value="FACT-SPT16_Nlobe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056595">
        <property type="entry name" value="Fact-SPT16_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048969">
        <property type="entry name" value="FACT_SPT16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013953">
        <property type="entry name" value="FACT_SPT16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040258">
        <property type="entry name" value="Spt16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980">
        <property type="entry name" value="CDC68 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980:SF15">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14826">
        <property type="entry name" value="FACT-Spt16_Nlob"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24824">
        <property type="entry name" value="PH_SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08644">
        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21091">
        <property type="entry name" value="SPT16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01285">
        <property type="entry name" value="FACT-Spt16_Nlob"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01286">
        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FACT complex subunit SPT16 N-terminal lobe" evidence="14">
        <location>
            <begin position="5"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="FACT complex subunit SPT16 middle" evidence="15">
        <location>
            <begin position="557"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="16">
        <location>
            <begin position="832"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="954"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="636"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="961"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="985"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1005"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1018"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1048"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4501831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1066" mass="119354" checksum="6AA40E27C342EF59" modified="2025-10-08" version="1">MLVELNKSQFHSRVDRIYSGWGSANQNEDYTSIADADALLLLAGDPAGEDEPMKKGTCFQQWLLGYEFPSTFLLFTKKKLCILCSASKAKILSQIEGSSGSIQVEIFHQAKAKDPPNDALPKFFEIYTSKKRVGILSKETHVGKLVSEWNKLVSEASDKPEMVDMSVAVSAFMAQKDQEELKTIQIASSLTSTLLKHHVGPRLETILDKESKISHEMLAAQIEGRLGSGEGSNAKGPDMKVWNKGKGLEKIDWQLVEFAYSPIIISRSTKTGYDLRYTAESTEDNIAHKGVLLVAFGMRYKSYCANVGRTYIVDPTPEQEAQYSLLLSLEAELLKFITDGVAARDVYQYALSFVKEKNPEYEKNFVKNLGFGTGVEFRDSTYLLSPKNGHILRENMTLNVGLGFSELLDKDGSKYALHIVDTIRVGKNESSLLTEGMKSTKDFLFFLTPESEDEKPKKPERKAPVQPRANGTPAKYAVAGKMLRNNRRAAQDEVHQTAAARLAEHQRELHEKLQAEGLAKYSEGGGEKGGKEGKGWKKFQSYRGEGALPPEVDRLRILVDRKALSVILPIHGFAVPFHVNTIKNAVKSDEGEFTYLRINFQTPGQVAGKKEDTPFEDPDATFVRSISYRTTDGHRFDSINKQINELKRDVNKREAQKKEMADVVEQDSLIELKGRRPVKMPEAFIRPAPDGKRLPGEVEIHQNGVRYQSPMGQKVDVLFSNIKHLFFQPCDHELLVIVHMHLRSPIIVGKKKTFDVQFFREATDVQFDETGNRKRKHRYGDEDEIEMEQTERKRRQILNKEIKAFAEKIAEAASASIGEPLELDIPFRELSFEGVPFRTSVRLQPTTDCLIHLTDPPFLVVTLSEIEIASLERVQYSLKQFDLCLIFKDFTKPPLHINSIQSSSMDDVKNWLDSVDIAMAEGPVNLNWGPIMKHINESPYEFFQGGGWSFLSGTTGGAESDLSDAQDSESEFEAESDSFEESASSDDGSHFSDASGSESGSDFGEGSDSDAGDDWDELERKAAKSDQKRADIKKSRGSDDDSDDDRTKKKKAAPKANGKKPVKSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZN9</accession>
    <name>A0ABQ8VZN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">DNA-directed RNA polymerase III subunit RPC3</fullName>
            <shortName evidence="9">RNA polymerase III subunit C3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_862358</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055207">
        <property type="entry name" value="POLR3C_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013197">
        <property type="entry name" value="RNA_pol_III_RPC82-rel_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008806">
        <property type="entry name" value="RNA_pol_III_Rpc82_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039748">
        <property type="entry name" value="RPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017919">
        <property type="entry name" value="TFIIE/TFIIEa_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08221">
        <property type="entry name" value="HTH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05645">
        <property type="entry name" value="RNA_pol_Rpc82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22536">
        <property type="entry name" value="WHD_POLR3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51344">
        <property type="entry name" value="HTH_TFE_IIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HTH TFE/IIEalpha-type" evidence="10">
        <location>
            <begin position="390"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="568" mass="63436" checksum="8814B98C78A31BA3" modified="2025-10-08" version="1">MADLHTTNLCVQIVSTHFGPLASKIASTLLSHGRLTLPQLVRFTALKPRLVRNILLVLIQQNIIWHANSETDGSGEEVLEINADECLMRLRFGAFVYQAEELFGVAGGEIVQLILHHGKLTSPQILQRLNAAATTTTFLPGEDKTPVVYSQALHKLVLLHYLKPSVASSHISPRDKRIQYEAEEKAKISGFPTSKQLREAKETVDARLRTDEEEVWKIGLKRKAKSQLPSTKKRKVTSTKEEDDMVVDETVYFRVNFDKFIIHTRNALIEKAVKERYNSGAALVVHAILKITEESQHSVADCRSDPLSVSNITLHLSSEEDEETLTSGLIQSSSRTMSSGSCIKEYLGILSSADNPTPAGRAGAFLELSSKGGGSGKVQMLFDVVARRLRRQVLEGVARERHGSEGVRVVRLLMDTGKLDEKQISKQVMMPLKDVRPLLSALSASSLVSIVEVPKSADRNPTRMFYLWQVDIPKAFSYILNVLYKTLYNISARRQAEREDPMLIAVLNKRERSDVSVDVEGLLSQHEKEVLKAWEEKQEKLGILEGRVEESVFIVRDLGRAVGSLEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZSM3</accession>
    <name>A0A9W8ZSM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_566180</name>
        <name evidence="7" type="ORF">C8R41DRAFT_270811</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="5"/>
    <dbReference type="EMBL" id="JANVFS010000049">
        <property type="protein sequence ID" value="KAJ4465692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZSM3"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4465692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="242" mass="27118" checksum="05E450A8FA99A2B5" modified="2023-11-08" version="1">MSLARATLVIVQALTNHWACTPPNPTQQKSRYHTEELYILQIAPLVFKLHMIIIWICAFFEVIYYLSTLSVFGTTTILSSVSPFASPLLKTLACPSTSTPRIGISPFFVIGIVAVVLGSYIRLDCFKTLGKLFTFDLTVHPEHRLVTSSFYAYVRHPAYTGSMLLVAGIAFSHLTEGSWLTECGPLKSNGSALVVWAAWWVWTLAVGVSRAEAEDKQMQKMFPGEWERYAENVAWWFFPGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B088</accession>
    <name>A0A9W9B088_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8J55DRAFT_497683</name>
        <name evidence="2" type="ORF">C8R41DRAFT_809188</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000002">
        <property type="protein sequence ID" value="KAJ4494797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9B088"/>
    <dbReference type="OrthoDB" id="2141050at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39218">
        <property type="entry name" value="OXIDOREDUCTASE 14 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39218:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 14 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="93" mass="10313" checksum="9647E3996793FFFD" modified="2023-11-08" version="1">MSMLANILGFSLFGLAARFGQLGIQKRNLFENLGGHALAMGVFGYGGYMAYRWDQTAAFLIEKKKAEIAESRKSRLAKAEALEAKLMAEKEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DTF0</accession>
    <name>A0A9W9DTF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SGNH hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_34589</name>
        <name evidence="5" type="ORF">C8R41DRAFT_838890</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000011">
        <property type="protein sequence ID" value="KAJ4485039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DTF0"/>
    <dbReference type="OrthoDB" id="2141316at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037459">
        <property type="entry name" value="RhgT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN ACETYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040737151" evidence="3">
        <location>
            <begin position="19"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4485039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4485157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="256" mass="26960" checksum="BBDE63E9736917C3" modified="2023-11-08" version="1">MFSLTVVSVLSLLSSVVGSTVYLAGDSTMAPNGDGAGTGTDGWGQYIGQYLTLSVSNQAIAGRSARSYTDEGRFTTIIDEVVAGDFVIIEFGHNDGLSGDVDNGREDAFGDSLTTTATVTETDGSTEVIHTFNYYMTNAVNSLKAKGAIPIISAQTPDNIWDGDVITAPPRFVPYAQEVAGNTSVTYIDHYDYVAQAYEAIGETTVNTYYPIDHTHTTVTGANVVAEAFVRGLLCSSSTLKNFVNSAGQAAPNGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWJ8</accession>
    <name>A0ABQ8UWJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_927169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000149">
        <property type="protein sequence ID" value="KAJ4463948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="380"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65896" checksum="381C89D5BBC8A82A" modified="2025-10-08" version="1">MSSPNSDEPTLPPPTTPVQNGQQYSQQDSGNQQYANYYIPPQGHPGMQGGLGTGGLNQFNYMPVHGHAMYPYSNMTPYSNAGPPTMGGQDQHEIGHARPRPCPHMNPADFTLPDSFGAPFQPNTASGYQPPPDPRPLSPDTFPSPSELAASAGNEAEDNGVAKPVNKKGDKRKSNAAVKPTKKTVDEDDEEIQFEEQTMRRGRAKGSGQYSHEECAEIVQLINKLLPTSGKGWDALSATYNKWAKNRNFPERKRASLQNHWNKLYFDALAAKKGISGKVSLGDIQDDDDGNNNSNDDEDIMDISSESEHDNDSKVVKKKGKKQVETVLTKAYKMEAPLRLPSRKTQSANFLDKLSISLDSQALQQRDENQTAASFQLLMLQNYQTQVATLTSQVNEERRRADDAEAELQMYRMLDRTRHRSPSRHYHRRSSYSRSHSPERSYHGRHHIQSPSPEHGFHGHSQHPLIRPPYTSYTMHSPMRSRHSRHAHSTPPSIKRYQYSERSRSPYCRSPRVATNSIVEDEFRSFDGDSAPLSPLLPQPIANRPTIASSSAVNLNDLASIAAGLPNAVAPGNTLSIRADNEGYFNVQNDSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXR8</accession>
    <name>A0ABQ8UXR8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000167">
        <property type="protein sequence ID" value="KAJ4463410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24968" checksum="C7DBD83B1E5C78CC" modified="2025-10-08" version="1">MATPSDLTSAGVPPAPGAPPSSPNPRDSDVDEILSLFKSVFGVGVSLARYIMDDPLWSILAAAGLPCPTCVRGKKTDALATWLSLVASWRSMETRSTNSTSALLELNPLDDQDQWDLDRQELREFRQQQPSVLGPLSPFPRTSPLVGDSSPPPRAPVTKKRKRLVKVDSGSTPKRRRPEQPVVPPVEGVSDYRRVVLVLRPPHVPGSELTTLLEAGQLVPADSSHRWFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY53</accession>
    <name>A0ABQ8UY53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7587 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_783311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056009">
        <property type="entry name" value="DUF7587"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24494">
        <property type="entry name" value="DUF7587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7587" evidence="1">
        <location>
            <begin position="16"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="235" mass="26955" checksum="028B60FBCEF52712" modified="2025-10-08" version="1" fragment="single">MYSSSCAPLIETATYEDCVQHLGWETRSSSPFISATFNFAWALWDAVRRFRGGMKHDVEIAVIDAAALSGKAVTTMQLLRRSPSSEKRHPRHRKWCRFAQESQSVLIHGSIPRSAVLASVPLRIIVQNLPSYFLQTPSSSRNIRPPIDPPFERILAWDPIGRKNASFRRFCQEMGDRFKRMPYHTRVREIAIGSVRLAITLLDPWFHRTVMHGDIHSAVIRIRELSALIAHWPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYB2</accession>
    <name>A0ABQ8UYB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000122">
        <property type="protein sequence ID" value="KAJ4465751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="386" mass="43590" checksum="B0A0941AC8233203" modified="2025-10-08" version="1">MKLRRSARQAMKLLTKRFPLLSDIQLNPAEVDVLAPRHVQLHQVGLLRHLTQHDHLQNTDPEFNILEQSLNAGFSGYDEVDFDAIEDLVVEHAATEAGAESKSHSREQENEDDEDTTGSRSDSADEWTPPSNTKRKRKRNTAPKTAKRRRRNSRTAVYSGKTTNATGAPPLPSVSYEKSLPAETRTEKFHALRPPNLSSKQWKAERKRQYNLWWQGRKHASSVEVHTAQDGFDVPQHSRISKPAWMGLRASADIRGSIQDAIAERASDVVHTILEGITRIPYVPHLAVAVCDLSNRMFLYRSQLTPNILGRILPDVNTAVPKFVRSITHGFSEDDMQNNSRGDHWFSIAGHDRNNRQRPEATKFQKNNHAAIASAFSPGQIFHTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYI6</accession>
    <name>A0ABQ8UYI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000138">
        <property type="protein sequence ID" value="KAJ4464600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="674" mass="75022" checksum="6820A5A3AAAEE19A" modified="2025-10-08" version="1">MWVIKSKILKSISAQSRVDSTLGANIKLPTDTAEAEPGSESRAVFRLSGISVKVETQLDFRGPRAKVEAHFDFRGSRAKVEAHFDFRGSRPKSRPSSTFGDLGPKSRHTSTFGDLGPKSRHTSTFGDLGLKSTSVTSVDVDDDDMEVDPSSSGASGTRHKAARLRVLSSDEEGDAPLPKKARSAIEPNSVEFHQVIRKGVVIKETFRYLESDEDFDKRIEEETKVKTEESIRWRNSLLEHTKKKLKENPTKGIQDHTKRRLLLFSTHFKILENVEAILDNYCQPDDSIPDKMCFFTPEDLEKLENIHTCLDEEPQDEDVLMDVDTIHNTPETAFLLLQSDEPMLNNELDGLTEDDDDDFLQLPPLDSPPSPPPSNGPSLVDLPEGMVQRSSILAESLTGHEMFTDEPRSAIPKEWIHVPKDASKDETKQTGTDKTASFLSLHSCSSPSYSSVPVDYHLQRQPQREPKPRTSPFVADDDPGFNIDGFVTELSLNSPEKKKRALFKLGKHSGPPSSIEPPSPIEPPSSIEPPSPIEPSAPLDNSGANEETSSKVVGKAVWTPISHRPKSAKFKVFEEFKDSLFALGISQCLERPFTCKIFWYFHTILVPYAKFDSRAYFFISTPVAAMSTGTAGAYTKSLGEQKYAQFCETLFKGACGPQVHHLGDHFRSYQVKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V055</accession>
    <name>A0ABQ8V055_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="530" mass="57096" checksum="1357D934134A6631" modified="2025-10-08" version="1">MSTFLSIPNNLDTLALSSASSSSISSSTSTSSLFENSCLFSSSSSQTDISLPTSPLNEDEEDDGPDKRKLLVEYDESWESSYKGRLKTPTLSASNASLPVPQHSQGLLKVESPATAADEAGYEAEESDGEESVARFIFLKNKKKKLVKSKTRSGQWTESLKQEELELSILLSPSMTQNIGQNLEVNPLTKPVLRPQSLDLNSPSPIVALPSPRSSSDSVPRLFWDSYPSFSSSSVDAISSPVVNINDRIHRETVLSKTTQKPLGLGLRLPGMSGPCSQKSASSIEIIGPLHSSDQTAKEKGLVGLGLKLPSGPPSTSLSDPSSSVLESVSAKRRCLSGLGHGHPSTRNRGPSARVHNGVATSVTTVPSSEATIRLVTPTQHGSGSILLPKIPTQRRASICLKPFLSSKDHHFTKRHMYPILESPGSCTVPTASASTTYPVSNSTSPPSSQLRKLRSFSRSENVGVNTCTNMSSSFRKSSSLRSFQRSPRSPLQQLVDHGSEELWHPAPQMDPYLIVHNNMLGDMIARTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V189</accession>
    <name>A0ABQ8V189_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_635383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4469016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14033" checksum="BCD8F72D50838090" modified="2025-10-08" version="1">MSSSSPSSTSSVSSSTETASTSQGPSTTSQGNLYLFTFLSTLLVLLIISCSIVFRSFVLRRRYQRRLAEALAVGAVLAPRVQGSRKKRFRTRPKFYDTWISDAEKTSIWADLMVLVNQFSHVCSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Y8</accession>
    <name>A0ABQ8V1Y8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EKC/KEOPS complex subunit CGI121</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">EKC/KEOPS complex subunit cgi121</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_870848</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the CGI121/TPRKB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="entry name" value="CGI121/TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011465">
        <property type="entry name" value="PRK14886.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840">
        <property type="entry name" value="CGI-121 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840:SF10">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="PF0523-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4470053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="184" mass="20385" checksum="0CB6089EC5645EEB" modified="2025-10-08" version="1">MLFYPVSNPAKIKQRIIDAAKSKAHEADEEREAVNFSFIDASLITSRLHLETAINQAILAESQGSLRTKTVHSEILFALNPTNNITEAIRRYGVSDTTKALCVVQIMNSSATTASISDVEIKMKKVVNGSIVSFDELAKLTDWNTVEKYHKLGNEVKEKRDAQRARAFIDNVAVSSVAMKSVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V265</accession>
    <name>A0ABQ8V265_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SGF29 tudor-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_912091</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20394">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047287">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="6">
        <location>
            <begin position="178"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="113"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="36534" checksum="31CEC41F4CD3CD89" modified="2025-10-08" version="1">MSRRQGMPLRPASSEEIECWNHAAASLSTLSAIYSGPATIETIGRVNRLISAWPADDTLPAEGLDSVKAIYKKLVSGLEEIRLISEKENKAIDNAMEQLGILIALRKAPEIISQEKRNKRPRAASPSAGGTPVPQVLPAPGGINRVSITLPARNSSTGPPAGTALPREPKARREAWAKQLPLQEGRQVAFHPPPNKGNSSVTESDDNNWILAVVDKCINGDKNRYEVHDPESVPISRFNTTLRSIIPLPDPNAPAGSPSSLSAYREFPIGSTVLALYPDTSCFYRAEVVATPTDTAPSVRSDTPYASTYRVKFEDDDNQELVVQAQWVVEWPGGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2B9</accession>
    <name>A0ABQ8V2B9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_853271</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF66">
        <property type="entry name" value="HISKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="422"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="923"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="599"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="813"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="827"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4469136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1067" mass="119252" checksum="0E8E6B6DF119D34E" modified="2025-10-08" version="1">MSTWTHSASSKWAEEVAMASMQKTSQNADEPSTTSMSFDLPIPVVQKQPFDSSLRRKFTFVSQLNCALYTKTTNIFRRVQKTLAAPSSSTVVRESLEGIQHALDNNRYALEEDQAVKVEEVNEDDVVEEVVVDRAWNEASTKTSLKSKALSESDGGEVCSEAPASVPGIQDPMKRPALLIVFWTLYSHWQQFFNPIFKDINKEIHYQKENWAHSKRLSLWASVFFIGNWILGAALIPTPAVLLDKIYYYGFAPCTAVPLVLLCAFNLPRDHTRFYQCFLFISTWSWSYYQVLFGFLCGYSGRNDLFTCGSKDFSSTFYYTTALQTVALFGLDLKRFPALLGAIIFIVLSGFLIIPEKVNWMRNAVNFGFFQVFLMYMHYQREMSARHLFALRIELKEQFERTQKAQINERKAADSKYRLTSYVFHEVRVPLNTALLAVQNMSASGTIVKSLELEFTALEGSLSMMSKVLNDVLDFNRMDSGKFESLSRPYAFHHVMRSMLLPLRLATDARKLELVTDLDMNIDEVARRAAYEALGEDHETIDRHMKEQPSGESHFGIVVGDETRLRQIVTNLASNACKFTPAGGKVIIRTRLILPSSSIPLHNEENEQNSTQDESLTTQNVEKHDEENNPENISRIVVRIEVTDTGSGIKPQDMAQSKLFSAFNQTEQGRQQGGKGTGLGLALVRLIVKLIGGRLGVRSRVEEGSTFWVELPLGIGVKAMLSADENNVFSSPARNLSSNTLRQLIKSKSRSNSTQSKISIIEVVDAAVQRATQTSPMTLRSNNALHRLMDQGGSVELNLANHESHTAVPTRMIGDRSTGTEIPMEVLTREESRRSDDASTHRIQPEMDNESNSLSSSKSSRRASARPTYVPLPSPRTLAFDSTTSMTSSLPTISPTHLPPSPLANRAFPPPSPSNPLFSHPLHVLVVDDDALTRTLMRRMLERMGCDVTTAENGDLALRILLSPDSDGESSSLSCSNSEQPVASDTVSKFHIIFLDNQMPVLSGVKAIAKLRDLGRRDFVVGVTGNALVSDQREYLDAGVDHVLTKPVLERSLRNMLQLADDRRKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2K4</accession>
    <name>A0ABQ8V2K4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">argininosuccinate synthase</fullName>
            <ecNumber evidence="2">6.3.4.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_777233</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="ASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="entry name" value="Argininosuccinate synthetase, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048268">
        <property type="entry name" value="Arginosuc_syn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048267">
        <property type="entry name" value="Arginosuc_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001770">
        <property type="entry name" value="PRK00509.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587:SF2">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20979">
        <property type="entry name" value="Arginosuc_syn_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="Argininosuccinate synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginosuccinate synthase-like N-terminal" evidence="8">
        <location>
            <begin position="7"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Arginosuccinate synthase C-terminal" evidence="9">
        <location>
            <begin position="180"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4470517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="426" mass="47179" checksum="DFC4715AEB9BE755" modified="2025-10-08" version="1">MPTNSGRVLLAYSGGLDTSCILAWLIEQGYEVYAFMADVGQEEDFAAAERKALKVGAKKFFLEDMKREFVNELIYPAVQANCIYENVYLLGTSLARPVIARGMIAVADREGCDFVSHGCTGKGNDQVRFELAFYGLKPDIKVIAPWRIPEFYHRFAGRKDLLAYAAEKSIPVAQTTAKPWSTDENLFHISYEAGILEDPNTTPPVDMWKLTTSPENAPQTPEQITIEFKAGLPVKVVVPDSSKTHTDPVDIFLALNTLGRKHGIGRIDIVENRFIGVKSRGCYESPGATILRAAHIDLEGLTLDRNVRALRDQFVTIEFSKILYNGHFFTPEREFITAAIPASQRTVNGVVKLKLYKGNVIIEGRESSEGLYDEQQASMDELGGFEPSDTTGFIAIESIRIKKWAQANIAKGQAGVAPKDVYGSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V319</accession>
    <name>A0ABQ8V319_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_781066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="108" mass="12166" checksum="E0C3D41E4ADD1E20" modified="2025-10-08" version="1" fragment="single">PIHHPLAFLFKLSYSQQSQWQVTRRAQRLHLPLLASSPRRRRQAMTLERAHSLLVSNPPLLQTSTRVPLGMHQLVLVLEREDGNPPAKVLGSNRCPLLGLTTVSHVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3D2</accession>
    <name>A0ABQ8V3D2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_592077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="53399" checksum="C44A738C3D451AA2" modified="2025-10-08" version="1">MSFDTTRKNSMASLCHTIRQNQRDNSGNGSFDSFDDLLRQHAMELGEDEPSSSGIVSSNKPSKRTPNNNTSTRATQINYSKAPPLAGSPIDFSSGSSSSSDADADGETDEELDAESDESSSDSSESDSDVDFMILDCNPSPREYSAKPQLPVDVSVEPGDAPFIPQPTQPVHEHDSVAVFASDYPAASSPRLAPSDPLQFTSPFHSPTLPHRAFTPGPFTVLSAEIYDKAAVEPTPPMNLPVTSMINPLQSVSKRKRVPTSSKRISKVRATTISDDDDEYKNNGSDDDDEYAPSPPLAPKSRKRGRTVAVSRHRTSRRKQGVSPSSASSQPTSSHSTPKRRRIAPESRNEQSDSPVLLDAIANTSVENCDFICPVCGWEQSNKRMPDYQRHLKTHLRPDREDKTKGWWCKGVRLEDKDEFNVRCEVNGSRRVRDDADPYWFHDHMRVGGCCQTFSRRDALKRHMANPNVRCGGIIAEGLKEGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V530</accession>
    <name>A0ABQ8V530_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="3"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="274" mass="31623" checksum="570A0A889E7AFBD8" modified="2025-10-08" version="1">MQGFRLQDLPVELERTIFEIAARLDLKTAMNLSLVCRQLKEWIQPLIYEMVTLGTGDTALFLRTMEMLPADFFARSVKRLCLTVSVDPNDAQRILRICTGISNLACWVDFIGRFALTRSTPFRELLHPLPLRRLSIEAAHFQTLSFPQCAWIHSLTYLDLVFWKEDSLLIRELRFLPGLTHVALLLQHSSIETSALAYILSILPSLQVLCLVTDEDDLERYEQGTRLVDPRVVCLPHPESVLDWEAPYRGRPDMWSQAEEIIEQRQLAANRMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5K5</accession>
    <name>A0ABQ8V5K5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trehalose utilization-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_897927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469:SF2">
        <property type="entry name" value="GALACTOSE-BINDING DOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469">
        <property type="entry name" value="SECRETED GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="258" mass="28589" checksum="F9472F3673E5F969" modified="2025-10-08" version="1">MGEHAFATNVATKVSIYSATEDFRHGSIPTAIQALQSKGPSPDIQFETTEDKAQFTDQYLAQYDALLFLDNIGEVVDDLGKAAWQKYLDLGGNFIGIHAASDCLRNTTFYGHEVVWPQTVDVIDSSHPNDFRYNLKSNPRTIGATIILSANEFSYIERGTRLDQGIAHPTAWFQECGAGAESNVIAGRSFYTSLHLNKTWQFRMNCFCYWRNYMDITMYNLQSNTTLAFNTSAQVGNPSVSVDPTNIPSSTTGTSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5P1</accession>
    <name>A0ABQ8V5P1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_847933</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="5">
        <location>
            <begin position="750"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="195"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="651"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="690"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4474545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1053" mass="117353" checksum="7C478F22CCFC8AC3" modified="2025-10-08" version="1">MSHALLLRLFLTPSFFTVHVALQYLTVYADNIGITYYITRRLSELDIAELRDVWGFVCHLLLTRPSKSRALECFVVEIAQKSTHIAMITLWFMQAALKDLSASPHDSPSFVICQRVLHKCHEIIFGDLPPPTTPYPTINLPFRSLFPRKKIKPHAEPAIIGMGLVLAGVPAMPRLTEIMGEVAIEQGRAEDKATVEVKRSVDSDDDDTAVTPSGIKSAVSMDEETEPESNEDNPPSPTSASSEPAILTRRRAMGPAQTVPALPLHLRGLQRSRRSEDPLGQLDAEHKETVTPYQSSPSISSARPPLRTASYSYADTLLQTYDTSSQIHLLKGHYCRSEVQFILSLENISERLLVVPRPARVSALRAELTSLNHKLPAEVCMPLWCTSSDSPPGSQLSHPHHRIVRIPPGESVVLNSAERAPYLLYIEILNDDLDFDPQKRINKDVLKKIVLREDQRAAGPKDLNPFTPLLPFQQHKAKSESLQESDLYDGSSVLLGNSLAATPPTPTASNDDEEMDLVEQLYGPGQSLLSQKIDLSESIVLPPPPKNKDLDRVAWSRPSSVHASPSLDNTDRHTLRIPPPLNLHLDNTIPQPSLVPAETPYSISLDEYSERMRTAAIMLAQLNANLVREPINGSAVPDGAHSSGPLSWIPGSSWLSNSNEPPKTAPHLTGGGTGSQDFGKPPPSRMRLQASEASAIRDRIMQEMLALEEERMAHMRENRETESIIRVGDISGGMKTAEDEGIIRRELSKVDPSAMVFSESWTAKKSRIRHVSPYGHLANWDCVSVIVKIGGDLRQEQLAVQLIHEFQRIWEEENCQCWVRYFRILITGGSSGLVETITDAVSIHSIKKAEYARRIAEGRFGHVTLFDHFKSTYGDPSSAKFARAQRNFAKSLAGYSVVTYLLQIKDRHNGNILLDRDGHLIHIDFGFMLSNTPGNIRFEAAPFKLPAEYIEVLGGVDGAPFLEFRRLFREGFEAARKHCDRIITMVELMQKESTLPCFAAFGEQTAAQLRDRFQPALTHSLVGELVERLIDTSLGSHWTRLYDSYQYYSQSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V619</accession>
    <name>A0ABQ8V619_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_539874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="21003" checksum="FB44B4643C83BBB2" modified="2025-10-08" version="1">MSFGSHPESFLEYALSLPDPVVPDPETSDSSDHSSPSEQNSEQESVQSGTNSDPDQSSYDSEFPGPFDYDYLYQSSDFDSDHPGPYDLSYLHSYPSSSASDSHESFHSFTSEASEAPELRPGDDRSGHPHLGPNGRLVDSERERRRVLGLCFYCGGEHMKVDCLKLQARTGENYDADDSESDIPGSDDGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6T0</accession>
    <name>A0ABQ8V6T0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_773096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="15326" checksum="DA5464D54035C144" modified="2025-10-08" version="1" fragment="single">PYCRFGCRALEDPHHLFVECKRYTEWRVETSKEIENRTRRKLTEKGFKETSQTNIWPLQYSFYYLGHIPKLDSLLPYSPTMTPIAREQLLYHLAADWHMHIIRLVGRIFGDYQQEMAKRLTSNHKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V852</accession>
    <name>A0ABQ8V852_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_922706</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="263"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="474" mass="53444" checksum="1E7B496A74F8C547" modified="2025-10-08" version="1">MADEQDTDTLLALVSSLTHKGHSTEVMLDALVQAEGNPELASQILNRGHPGSEVAAGKKRKRASDLDSWLKGPNHAKPVSRHASPLSSTAPSSDPPIRKVNRGVDLMAVLKQPPPSKKTTPRKPTLILTNPQMVAEHTPCTMHLSILPLQLASKLFYSLEQSSRDWQRNKWWLFDRLVESPHRTAFFVRKTDGVSDDETWHESAQYWYNGRKTDPPDVFSSEMEEACEIIERLVTDEIRRRPYRYPLEWAGGGVDSTNDLIWRANVAASNRYEGRNESVGWHSDHMTYLGPHCTIASLSLGTRRMFSLRETVPLHETEIRGAQTFNIPLPHNSLVIMHASCQERFKHSVPPQSAMDVYRPIHPRIPGGPIEPFNCRINITFRFYRPDFKPPSIPLCKCGIPTVLRPDMKNQRDGQEGKYWWTCFAGAQNDGKSCGMWKVMDMEAEGRGPTVGSMQQTGASSSSSSREQLQNARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8D6</accession>
    <name>A0ABQ8V8D6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_905631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="128"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="442" mass="48196" checksum="60B86B4501F10706" modified="2025-10-08" version="1">MSSFFPSLSTVETLAKGAFATAAGLGTLSAGLLYYGQSYLIYPSAYIKIGEDDGVPSKPASYGLHHESVDLKTKDGQTLKCYLLLQKKDLPKATKYSSLPTVPISAIEGATESGYAELADEELVSHRPTVIMFHGNGGNAGHRIPLGMMFQQVMRCNVLGVEYRGYGDSTGTPSENGFAIDAVTALEFVRGDTRLRNTPVILYGQSIGGAVSIDLASRFPGEIAGIILENTFLSLRLLVPHVLPLLGPFRWLCHQRWESAGKIIGMSDVVSQTRVEDRLVGLVKEKIDMKVKEAFKERLANANDVLNLAASQALEGGGGSLARVGKGLGKEYKGIPRETNVLLLSGQSDTLIPPIHMKFLRQVFEARPHTRRTLGLSPLPAYQEGKSQDTVDEERSQFILFPGGTHNDTTAQHGYWNRIGDFIAEVGKEWREQQKLGNDSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8G3</accession>
    <name>A0ABQ8V8G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_500059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF2">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY SUPERFAMILY (AFU_ORTHOLOGUE AFUA_3G13450)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4479900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="29853" checksum="19A71F008EDB1679" modified="2025-10-08" version="1">MTIALVVGASRGLGLELAKILHDRNFQVFATSRSPVAQIRKELGPDFPQEINIIPNIDLTQRDAGERIVSYLKGDLGLGVGLGETRKLDLVIMNAGVFKADTLENPNWEDLLEMHKVVSIAPLMVASNLYNSSLFATPSKFVIITSEGGSIALRTRQEGGGNYGHHSSKAAANMVGKLLSNDLYDKQVTVGLIHPGFMKTDMTKGVGYDEFYDSGGAVEPSEAAETTVEFIMKELSHDLSGTFYAPRGPRDIGQAERVLIPVMGKELPTPLLLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8L5</accession>
    <name>A0ABQ8V8L5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Long-chain-fatty-acid-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_843658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="88"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4479497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="689" mass="75686" checksum="A8245FF48034C5B4" modified="2025-10-08" version="1">MPLVRDHIEGYPETIPFTKQGVVVPGTKKPGQTGHYRNGVWGLLTRDTPNALTTITEIYDSGMRAGKDAPFLGRRPLISTNPVKYAPYYEWQTWGQVDHRRRCVGSALTLLFKTGKLGGAGELETVGIWAMNRPEWQIVDLAIATYGKVDVSIYDTLGKDVVEYIINHSHVTSVFTSADHIPTLLKLKPKIPMLKAVVSMDDFTAETRTILTQWGWSVGVHVMDMKEFEAIGEANLIEPIPATPDQLVSICYTSGTTSNPKGAMLTHGMLALSVQANLYGLNLPDEGSTMSYLPLAHIYERITELATISTGAKIGYFSGDPLRLIEDCQILKPSLFPSVPRVLNRVYQAAMLAGDVPGLKGTLFRKAIQAKMEKLHATGDNTHFFWDKLVFRKIQAVLGGNLVLVTCGSAPIHGEVLDFLKIALACDVLEGYGMTENCGTCTKCWPFDPSASGTVGPPQSVNEIKLIDVPSMNYTSEDKPRPRGELCARGENIMKKYHKDEKNTQEAVDEEGWLHTGDVAEIDDFGRVRIIDRVKNIMKLAQGEYVAVEKIENTYSSSAAVAQLFVHGDSLQSYLVGVVIPDPLHLSAIASRISGSKVTPEDVKSLGEACKQPEVIKEFVSILDKEAKKGGLKGFETLKRIHLSLNPFSVEDGTLTPTFKIKRKDAYKKFKAELDALYSLGEPGAGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V924</accession>
    <name>A0ABQ8V924_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_776286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1070" mass="122089" checksum="292F7D3BD9A426CF" modified="2025-10-08" version="1" fragment="single">MVTRTVKKPSEVKIVDQINLLLILVGSNFSHFIATNNDWTAEARFPTLFAHRREHINQDPTSPFFPWPDRETCVLDILRHVPCCSFSRKQNAAIHWAMLALGVPNLPSDKTMDQIDKEMQRMCGIRSIRYDGKLGHVYYANDLAAIIAQEMSNPSVRTHMHFSPEDSGCRLSQANQAERWLKELDPDLLTPVHHTAGQDFFTLEPTVLKNGRICMPSRWFIRNKRVFAKAWPMKVVDTETYGRGWAVQTFSEFEISESDLLLAFKQFQTSYRDLGQISPSSIVGMCFELYLAYSACIDLMQAEEKSNEEFIAWEKTNPNEGNRWRSKSQGKRVVAFPIWLYCDDTSGNVSKKWNKHNSFLFTAAGLPRHLSSKESNIHFLSTSNSAPPLKMLDGIVEQLLETQANGVWAWDSQLKDLVLVIPSVLALLGDNPMQSEFACHVGFRGRLFCRNCWASGKVSGDGEENTNIHPNDGSDSNVSVNSLNSNKKSKRKKTLESMKDMITRISEFMKVKFMKPRNREETCKELRSQFVEGSRIGGGTSFKRMKTDSGIKDTFQGEFVDRIQAIATRKGISRERREQEIMRLKNSFPSHVTSPVWRIKGLDPHQDTPVEILHVILLGVVKYYWRDAVARISKKDHEILIGRLSSFNTWGMDLSPLAGKTLVNYAGSLTGRDFRALVQAAPFVLHGLLSNEQVEVWKALSALVSLVWQPEIHDIEQYLVNLEKTIDYFLDCTCRLTPRWFNKPKFHVLLHLPNHIRRFGPAMLFATEGFESFNAIIRTQSVHSNRHAPSKDIAYSMARNNRIRHLVNGRLFWTKIDIDSCRQSSSSKSFHQRLSDNPWEFSNLDFWKTALTSIRLGLGNLSAHIYFSDTVMGRKNPSQHASSQSEICRTFEGVLLQSGDKCQIKNWVIWNLSDTTGSSTAQVGLVVEILQMSPSTAEKEGLVSTLTLQRVIVGEQHSHYGMKQLELVDEYFSVNPQDILCVANVQHNCYDSKCPVTRTGRVMKEREESTEKELQVEHTGSQSFILNTVQMRNSAYLEPFRQQIPSLNREQIICKAVCLEIDNRNKQRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9G9</accession>
    <name>A0ABQ8V9G9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_842588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045869773" evidence="2">
        <location>
            <begin position="27"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="271" mass="27007" checksum="9A97D4A1E8FC3174" modified="2025-10-08" version="1">MIMTLVKKSVVTICLGLALEFGCISALPQQASVTLFEFLPSGESNNAVQGTEWAQPIGTASDGSETTFIVENIQSTSGLVSSNGAIVLTTVTETAIETIVVSASGWAESNFPTTTAADSSQLGGGLDCHFTASASGECVEEEVLDDGSTSTRTLSGGVTAQILAISTGTLPSGVGVSAITSDSQQSTITVVSTTSSNQQSTITVVSTTSSNVQSTITFLSSSSSSTSASTFGSPSASASSNTSSSVHKGLGTGILAVIVGGIMLGASATLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Q9</accession>
    <name>A0ABQ8V9Q9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_770457</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ELP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037289">
        <property type="entry name" value="Elp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 10" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="194"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="297"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="412"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="612"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="658"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4482703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="792" mass="86587" checksum="5956CF65DB82A2E5" modified="2025-10-08" version="1">MNISTAYIAASTNRFSGASDVTPEGTVIFGSSNLIGIWDIGNDDRGISMTIPGHNGAITCVRVIGSHSFVSADDKGEARIWKKTESTSQACSKNIWTAFANFSAHKQAISALAVSDDWLATGSSDATVKLWKLPQDGTAVENLQTISLSGRYPLALAFARLPQSNSLVLAIGGTDKNIQLWTRSETTFVQSAVLGGHEDWVRGLAFCPPEAEGPLILASGSQDATIRLWNIEIYKKEMISRPQEGLSDDLLDAFEESLGDFGIADEGGRQISLKRHILSVKSDQEHFIFSVTFDALLVGHEAGVISVSWRPSNSNQSTPTLLSTSTDSSLILWSPATILTDPENRTKSSTIWINRQRYGDIGGQRLGGFVGGVWRLDGNEVLAWGWSGGWRRWRRKPSATNDDEVWEEGGAIGGHRGPVKSVDWSSTGTFLISSGIDQTTRIHGAIPQVNGPATWYELGRPQVHGYDILGSVFLKELKFASIADEKVLRIFEAPRRFVDLMEILHVSQFSENEKNRPMGASVPPLGLSNKADADGAVTVAAPELRRPFEGELASVTLWPEVEKVFGHGYESIALATSSSRQYIASACKALSPEHAVVRIHDTTTYQPVGEPLTGHSLTVTQIAFSPDDQLILTVSRDRSWRLYQKAEGGGYIPMVHESKPHGRIIWDCAWAPEGDIFATASRDKTVKIWGQSNRNNWPCVATLKTEESATAVNFTAFDSRLKRYLAVGLENGKILFYSSSKLEPIWTLGMTHSGHVGQINCLRWRPGSGEQFREIASCSEDGTLKISIVQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9V6</accession>
    <name>A0ABQ8V9V6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_922023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="462"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="818" mass="93048" checksum="901735F4BDEF056E" modified="2025-10-08" version="1">MEAPPETKLATPTSLPEQKQSDPPPSVGSTPESNGAAHHTQDYAPQRISTLTKFLEDDAHERVVFSLDELVTLILDLPTDWKIKEESSLPPTSTAVIEALGAYLKVAIKIAEGERKKWRNAATNEIELNQPLTKVLNTLRDGEGHFTKDNDEGIFCIEDPHLVLGSLLERNGIYSPLLKLTENKKLSTYLADKNIFGVFWGLLLLFVEVNLRKKGFADPNIQRAEIGVPLNESSNFTFSQQRRSHPKSNKRLRSNEELDSTNVQTVKVKHPDPLLNMHLDQLPAVEIQSDASTPLPSTPSTPTTTGLKQKDRLRVTIQCKNRTKTVEIATLREARGVSRAEQNVIQTQGQHPTRKCVTEMISTESMNHGFSFVNYRGSEVDSEPNDEWTKLVLAMICQLKKLPTEKLVFVPTLVLNGFDYLRDPEQFLQEFADDPQDLIDAVYCFKEIDGRTRKVIIKSILYHAKDIVGLHSLIADVECLCTKTGCKWHGNEKKVMKISFMGTARQSEQGLIGEARSKAESTGELWALNHLPNVIHSLSLLPNRRKASHRRLKKTLKEKYEEQAMHVTVLEQLHPLSGLEDPRDFAQVFYDVLQIHQWLYECGGILHRDLSSGNIMFRRKDGKIYGVLNDFDLSSRVEDMDNGDIRTGTRPFMSLDLLNSYWEGGHLYRHDLESLFYIILCLTCRYEAPGVPAPDPRAYSKWFSGSDQDILGNKNTFLTSPFLLAQDLPIQPYFAHFVPWLKRIRYFISEGYHARPRPQLEPVDDTDILDLPEDMQPQVSFNWQTLGGQVTYSRFRRVMSSFKDEPLETRWSDGQAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9W2</accession>
    <name>A0ABQ8V9W2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gryzun, putative trafficking through golgi-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_840527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021773">
        <property type="entry name" value="TPC11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374">
        <property type="entry name" value="FOIE GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11817">
        <property type="entry name" value="Foie-gras_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 11" evidence="2">
        <location>
            <begin position="488"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1179"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4483112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2047" mass="222661" checksum="A26DE47DCC89D45F" modified="2025-10-08" version="1">MNSYPLELIAQLAPVMFVAGLNPASMNNSNNVPNTTSPPLQSIQPPPPTHHSRNPSLTTMTTVSGADSVNYPLSLPPSTTAPNLLRPDPFNILTSRLREILVHQRKITVWDTPTADKVFQVMLIDKDVRFPPRKVESSPGAPAHSPLSPLTPSSPLHPDGLIAPIWIRKHTMLVPAVFVLFIRLFESDDPSSIYAYSLGGEHNTEFEQRLKELRDLADRRNDKDTDRVVERVKDLERLKDTELAALIAQRKRSTNERGIKLTVVLMASRKLLDDSASGAAGGLGLDARLTFIRRQSGLDSRAALFVLSPISREELNDFVKSLQTALWDPAVEYYTAHSKRVRQKRNRHQAQSAQSSHRPTPSIVASSSSTSALGAMSALPAPLKPEGWTVRYEYKMASFAEFRGEYEVALKHYQDAYAALTMLFMAPGSSLAMASGGAGVTMPISTSTSTSTMPTSTSSMSTTSSASAASRAGVSSPVPNNGGSRTKRWAEAKVLADTINIKIVKLYLYNNETGLALAQQRLHVRTFPVVAGFTGGSAMSTKTGSAPVGGQITPSLNAADEGSYEYWSWVSRMWCILAEMLVEGTRTRGSPGSPPIPPSLIIPIHRPRLSPSPAAVPTTDSGSRKPSPTPESLLHSAAPGVNPAHALMHPGWYYLLAAECAERKVGRFVEGLNFGASDEMKEQKITHLRALVGDILELYTKSYELFKAYSSASTTTTTNTTSRTHTLNASISNPLSMTTSISNASNAVGPSNPPTNTSTSTTGRLALYIAHRIALTYARFPDPNRPDIRSTNSSNDTLRMSKDSKNTGDPAADNAEDLDEPGTSDNAPHELDSLSAEFDSWAREFSADADEDESESLDEGNFRGKDPEKLALAARFLARIAKSYWREGVISSSSSSSSSFSASTFSSAYPTLPSMFPGYPSNAGFLTYPTAKYNTEDDGENDEIWGWPALLVPLLRTWSGILRELVGRGINETRKLFKTFRTLQKLDSLYKPSSTLEKLESLEAHFDSYTRVLISRISVDRDVEFSRKKEEMEIQRELTRVMKMWVGVQTLKGVLNKASSDTSSTREVKVIRVDNAETQPIFDTSVVFWYGRIWMSPFFPSVSSLPSSSSSNAESIQESTPFQLTLTAPSRVAIDKLDWVELRVRVTFEYEGYDDFDEGYEKQKEEGEERDKEEGGKEDSEEDDEEGDNREGTIRTDVEEANIDLRTQEIEVIIRSNSLSQGGEAIETLNEPVQMIDVGHLSFGTDFGFDKADYDRKSSTNKIQEIISVSSSSLCWIPGQAMIVIGSVCVCSSGGGDQFGQGKIRISSVLLRLNAPTPFPPSPSIPNTPPVVLEIPLHVPARRGAPPPPTSYVHAPGSGELGAGAGVGGIHMQAMWFAGFAEIQHRHPQYGIKAPRWVPVSRRGIEKGLGYEGVEVSLRPHPVTLSVLHSGVAYVGEEYPLEILVKGCQCDFGSSCPADAEEGKQEEGTMDEEVEVVMDVLLQPVESDVTAVNTISVGPHQSNTMIKGISLGLLALHPQHSSPSDLRHTLWIKNTGGAGDRVVDMSVWTRPIHKHKTGKPNKNTSGINVRARSMRQLPHLETETLKTVTIPCIEPLNVRYDVTYQRRVDPSSYSTLNPGEGALWDRPQIPWWLDEEKDDHGDEGEGGNRDIGDTWDERVEADVEAVLRTTILCVGGGIADSGGSTSGSGLTSVASLGVEVEKVVLRRKDPRSTIVKILSSEMILGSEKAVVKDEGEEQEKDGELSLFPLEFLPGDQLSDVCRIGISSHRNDEEIYIDADGELEIPSSGSYEVHWRRILPNNTRGTPSSTKFPLPALRPPTDDLIALLDVSPTARLHEPLAMTLTIRNRHPTRTADVYVQLEFPPGTGVAANTSAPTGTSVGGAVPMGESTVMSNTTSTAGEQGGQSAQSGSAFVIAGLRAGRVPLLLAGTEEQMVWMLIPIECGYVRLPKVQVLDRRKAAMGTAGMLGAGSIGSSSNARSESIVAVAGNAIDNVDKNGSNAGGREVRVVDIRSEYRAERTKRQVGTDLVRTEEGDDQGRIGTVLVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9X0</accession>
    <name>A0ABQ8V9X0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_774217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="142" mass="16309" checksum="3A45F6934B3D34A0" modified="2025-10-08" version="1">MHPSIRLFTERVHTPLIRFLGKRSWPPSKTPHAHPFAPPEFRNKNYTQFSKAPDPVSSSPFPTSSESKTGNVFQEFWEAPERLWKPRVHHLEEAEIDAILVRRRVSNVFSGSDTILLGYRVVVHLCSRSFVGDLVSEQAFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA16</accession>
    <name>A0ABQ8VA16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic peptide chain release factor GTP-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ERF-3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">ERF2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Polypeptide release factor 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Translation release factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_868877</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03704">
        <property type="entry name" value="eRF3_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003285">
        <property type="entry name" value="Sup35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01343">
        <property type="entry name" value="YEASTERF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Tr-type G" evidence="15">
        <location>
            <begin position="150"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="15"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4482745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="591" mass="64603" checksum="4C72049D828EC553" modified="2025-10-08" version="1">MSKLNAGAFEFVPGKSFALPPQSFQQSQAPLPPPIERPEQTEAPRPPPTISLSIGGSKPSAPTPVVQSNPAAAITPSNAPTSSAASSQTKSTPVPAKISVKVKSDSPAPPTAPSKTFSLEKSKTDTNAIAKEVQAAADKAVLDDLFGNVKEHLNIVFIGHVDAGKSTLGGNLLFITGAVDKRTMEKYEKEAKEAGRETWYLSWALDSTPQERLKGKTVEVGRAYFETSFRRYTILDAPGHKTFVPSMISGAAQADIAILVVSARKGEFETGFERGGQTREHIMLVKTAGVSKLVIVINKMDDPTVLWDKGRYDEIKDKLTPFVRAAGFNPKTDVTFIPVSAYTGLNLKDRVPKTTCPWWDGPSFLEHMDHMPMVDRKINAPLMMPVSEKYKDMGTIIVGKIESGHMRKDDRLVLMPNKDQVEIAAIYNEIEDEVPDAFCGDNVRIRIRGVDDEDINPGFVLTSPLKPIHAVRQFEAQLAILEHKSIICAGYSAVMHVHTLAEEVTLVSLLHYFDKATGRKSKKPPQYAKKGQKIVALIETTAAVCVERFTDYPQLGRFTLRDEGRTIAIGKITKLVEGTEEITDGVANLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA33</accession>
    <name>A0ABQ8VA33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_840095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056890">
        <property type="entry name" value="UBA_DHX29-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24899">
        <property type="entry name" value="UBA_DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="675"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="953"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4483983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1490" mass="166634" checksum="C2AED950CCE8C5A6" modified="2025-10-08" version="1">MAKKKKTQLKPVARGFATISVPKKVAEVESEDPLSQPPLDDQESAEALLTENSNGSKEQQNVQDEFDLDKVEEQSLQNLVDRYQEKTEKEIVRNVKAIEVDRRFSKTLPSIELDSSIIDRVLDFAKELQVNEGKKTLEESEEKAVTKLAITYGVLRRLGFTEERVTECLTDINGVDLEEAYDWLFINCQEDELSNPNGNQEELRLPTAPNTPKGSMARTPRTPRTPAEFLIPSTPTPASKYFKKKPSSNLDANAPVFIPSWKSTVDNELTSDSASALHASPLPVFSLEADEDQSDISVVKSRILASFRNGSGSDTDSSSENDLNDEYVRLKLKIASLSTHRDVSTSLQLQELQNRLSILQKNYFFNEREAEKLYAVARKKADIASLDARLRGVMADADITNTSKSPKKRPVEIQTSTPEISTTVDVFDLEDGAEGGVLDILEEMPNSEITTEGVTVSVRDMALPKHWSGRTSKILLGETVAKSDRYAVVTYSIISGSSRVKRASVSVRWEGRKTDEWFMVDVACHDEGQAEQYVATLALHALTFPSTEGFAAGSSGGPQTFFRLLPPVYRDLWSELTDARKLKDDAINRGVWANLRSIVEPKLSVSSKDQGSIKIQHATNENLEVASNRRLYPNGQAFSEQLMSNFLARQSTSAYQEMLVHRNALPIASYRDIIIDTLEQSQVLVLSGETGCGKSTQLPTFILEDQLSRGKPCKIYCTEPRRISAISLAQRVSRELGEGLNAAGTISSLVGYSIRLESNTTKNTRLAFVTNGIALRMLEGGSGQGGQGTAFDEITHIIIDEVHERSIESDFLLIVLKSLLEQRSDLKVVLMSATVDAEKISEYFGGCPMLHVPGRTYPVDVRYLEDAVEYTQWSISENSPYARRVHDKFYRTKNKTEWAEELAINDDEDSDIPSENVKLEKRYSPNTAATINLFDERLIPYELILRLLEKICFEDQSLSNCSAAILIFMPGLGEIRKLNDILTEHSFFGLDDFKIYPLHSTLSSESQSAVFDIPPPGVRKIVIATNIAETGITIPDITCVIDTGKHREMRFDEKRQISRLVETFIARSNAAQRRGRAGRVQEGLCFHLFTKVRHDNQMVDNPLPEMMRLSLADLSLRIKIMKVKLGSSIEDVLSRALDPPTPVNVQRAISMLVEVRALTSSEEITPMGRLLSKLPTDVHLGKFLLIATLFRCLDPALTIAAALNSKSPFLTPFGLEQEADRAKASFKSDNSDFLTLHNVFSSWRKAGANANPAFVRKFCKQNFLSHQNLQQIEELRQQFLGYLIDASFIQVDKSFIRDLNRARYSRNRTRFVPVPPELDSSSSNITLVNAALLAGLYPKVLAVDVFKGQMRTLSNNQQASFHPSSVNFGKKPTDLGTNHIAYFTLMHSKKLYAWETGPVDDMAMLLLCGEVDFKLISNAAFIDRKVKFQIAPKTNIALKFLRTQLTSLLWYQFRGKILTESQILWNELALMVLGKVKIEDLHAPSITISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAK5</accession>
    <name>A0ABQ8VAK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047323536" evidence="1">
        <location>
            <begin position="21"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="71" mass="7788" checksum="D146AF964E8ACE0E" modified="2025-10-08" version="1">MQSKLLITLALSCLSAFVAASPIPAPIPALVAAVHDLESPRVETLAREQPSLTREEIDVEEREPICRYDCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBW1</accession>
    <name>A0ABQ8VBW1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_439625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="36498" checksum="693F129F47E4050E" modified="2025-10-08" version="1">MIGFSVILKTSIDSDVPQSKTCTLAEMPGVLILSNGTCSALPSGSSVVIESLHVTFIWIFNGLQIFGFIALTTLTLTAFFSSHIKRAATWYTFMIGWIFWCISYFALIGQQTGDCPGFGFCLFQAALIYAGPPANACASLAILLQLRLSMNFDLYGSGNQKWQSIMLIAAPPVVYILVFIATLVYGLLNAAEVQRDPTGMYCNLANGIPTKIIRTFRMLYKNRSALRSLQAQRRSSVPVTMIVRISIFSFLPILALGLSVFAVVLTNGGSTENILSNIMTASLSGAAALIFGTQQDLLHAMIFCRRRKVKTVPNETAAQKGVSICVSVSVEDKDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCA7</accession>
    <name>A0ABQ8VCA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_981957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="427"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="840" mass="94191" checksum="EE805B9013C6BC04" modified="2025-10-08" version="1">MVVNKKQNFPAAPTMGSRTNSTQPLPRAKATSNSKSLSTAGPPQKKTKPKKPSKTPKLRTKSSIMDRFLVIMLAIFSTYALWTCPSDIHLSNPICRSLSQYRTHVLDPYVLPPVQKALLHPYVAPAVTKFYAVEHAVAPIVIRAHAVVQPYITKATQLTQATALTAYAKLVTPMYNKHIQPLYQKYVDPLYMEYVYPRLHLLRSRVLDPYLRPLTLKTHLYANKLFWTLHRIYLAAAPRIHSAYIRARPFMDRAWEVAKPHVVQSVDTGLKLFGLLLEKSAEARRQFVDPHVIKIWEKVVELSGSSGTTTTSTAFSVSTPISETKATSAEAEVETVQSGSSSVPSASISTSLSVPLEPSEASPVPEESSLPLETLTSEDPTLSSIITGLEASIISEIFSASTTSSLTSSEHESTTASYDSTLTPDIANPAETPLAATEPASEFEAPIEVEQDTSWEETLDSEYASSTSEDDLDNFFADLGLLENEDKETGDSTETPVVETKQDGAISPEESAAARRAATAKKRAELEARMEKWHADLDGLMKRRTKEFRKELVRVRKGAVRSLFPDPEKDNSDLEEALTHIRGEDVAGILERFEKESEKLLKGLESYLKKEEKLVSDSSDVDVDDRMKRWFNVVKRVEERFIERINGLQEKIHWWYLEVRELEVQEYHRATKEVKTFAQKAQGNMGMPMAWLDDVTYQDWQKYHDLIRAHERFDEQIRMIQNGTHPSPPIDPLVPALDKLQLELEDAKNGFDTRVRTLSAQIHHVLSPPQKEEHEGEASSEEPVSGEGEEFSILPIDPVPTSPVMDGEEELESTNIIIGKSKEQVEEAIRIAQESVHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD28</accession>
    <name>A0ABQ8VD28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF572-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_796687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4487409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="307" mass="35002" checksum="0992606A0EDB448D" modified="2025-10-08" version="1">MQGFNKYYPPDYDGEKHGSLNSYRGKHALGDRARKLDQGILITRFELPFNIWCGTCNNHIGMGVRYNAEKKKIGNYYSTPIFSFRCKCHLCDGWFEIQTDPKNTRYVVVSGARQKDEEWDPEENGGFAVHDTDGNSAPVDPLAALEKTTDAQIHQTKVQIPRLESLMDVSDRYNSDPYSLSLKARKHFREDKKIWKEKEKSDTQVKDRYALPTNLSLAEEDGETIKEAKEQWRKGREEILLRDSKRRKLAVETSIVPSSSGLSSTSSSAVVESLRARVLINTARQSRTSTNSASTFVNSRKSLLRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDY2</accession>
    <name>A0ABQ8VDY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_834677</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4489820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="533" mass="59444" checksum="69530E04D7E19C2B" modified="2025-10-08" version="1">MLVLTMTNIYQALPFFFVIWTLRIAWTRLQCRRWDIGNLPIAPMKHSWIWGHELEVSRHEACEMYVKWSTFVGSVYRVKAAFFQPDILIVNDTSAVQHIFQNAYNYVKAPAFLPIIERLIGNGIVCAEGEEHRHQRRLLAPAFTASAVKSMSDDIFACADKMSHKLRGSINEQNTIVDMVPLVSACTLDIIGRVAFGHDFGGGESNEAKEIASAWHEDILMAHTFGGFLAPRLINLFPWITSLPIPVIPGESVSKRIVDRLAGKLLQEDHHHFTSNARGTDILSLLVEDNQKKGKSDLRLSDTKLLDNITTFMMVGHETSGASLIFTLLELARNPTVQRKLRQEVQAAGNLDYDRVQQLEYLESVVKEGLRLYPALPVTERVALQNDVIPLSGPIETKNGNIITSLSIKAGQVFHIPITALNVSTQIWGQDAQHFIPERWLEPGGVPPTDKLPRGPWAGISTFSDGPRSCIGYRLAVSELKIIIAVLVRSFELTDTGAKIEQYMLPTLQSFADGKAASMPLKVSLVSDEQRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEG8</accession>
    <name>A0ABQ8VEG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_766078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="877" mass="97675" checksum="ACFAB0BFDDB84B77" modified="2025-10-08" version="1">MQGSQVQRLLPTPPHPTPPSLQELSSEPRMSPGASPPIHQLNNITHYPRPMNRVPPPQFLSNLHDLEQNWQMTDELMAEIERADLQQAQGLAAAAHIYPSYPVGSGYNATNVKTDSSPRDPGVERVRAAEKSSPKAVDGQLGRRPSVRESRESPKARDRPSFSPNQSQTPERRKSPPYITPLGSPGEQYNQYHHEPASVARRPAHDSRPNLTLATQTPPLQAISARTPDKSLPLQEEPEEEVPVAIKAEANGREHSRYMHQIHQQREPELGSPTPSSDLNPEGSYIQDGRSSRAAIRPEDEDTLYEKSDKQESSNDDSGTPRSPSAGIPAAENTEQNRFWPAQQTQPRGAVPALHRGRGRNGSTDQLGLRGLDTSLFAQVEQARTSEMPPQYAEAPKPIPRPDPIQESYAHYYAQHMHPDDLQGLMDDPTSAYIQAYLRSPRPDAPIPPTPHSQTSPPSPSPMLSGRYENTKDSYPPFSPVAPAGSPYPYPFTHVRRNMSYSGHSQTNSNLGLNPAVIQEQFVKQFQMYAQNHSGNITDSTLSPSSTPYPPTYNPWAYWHTQRLMGGQIPDTVTRQSSPSHEPIPLPPHPPMVSLRRKSDSSNLRAYRPAPKANRKPPPRVDSTQPRETSPEPSTSGEETAGEDTRFAVSEEGNWVNGTTSAIPIPIPIPIPIVDDASSAEWVDEDEEEDEEDLLELEYHPTYVNNVEKRRRRWETKWDALLQAFQTLDRQTDATMVLLAAPSHSTKLHLVTSRSIRRLPAIGHSQALKGVRAGFRQVAAQRRTSRSHKASLVDRFLNASSGSGDGSDGSSESNKEDMKRVLDAALGSLNVMRNMYEQREARWVEEMRRMSEDRERVEFLLKQVLGDGHPVAESTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEI2</accession>
    <name>A0ABQ8VEI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD/PDEase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_766205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569:SF1">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="23494" checksum="C2A44239C08267D2" modified="2025-10-08" version="1">MLAHFVPLDPVSRHAYALSCEHLPPAILNHSLRVWVYAATLSGLEKLSSSRLPLLFTACILHDIGATPAFSNLDSEKLQRFEIEGADAAASLLREAGDSSFSQDDIEEVWRAIALHSTPQIPERMGGLVRIVRLAVLSDFQRGTVAGKEGLQEETETHFERLEIEKVLGDAVVQQALRSRVPEAKAPAASWPHDLLRAHREYPEWEGVNKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VER1</accession>
    <name>A0ABQ8VER1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237:SF9">
        <property type="entry name" value="NEUROGUIDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="42987" checksum="EA9882B620435D40" modified="2025-10-08" version="1">MSSEDATVDTQQVCKLLDDMTASMASAREAIESLKTKGPSYFETKDGISLLSLKHHVLLSYMQSLLLVSTRRALGHSLSIRDPPSEPFSSLERSARGAGSGDLVDQMIEGRIVLEKVKILEGRMRYQIEKLVKAAQQKEKVTDDIINDPLAFRPNPQNLLDTNVDDDDNDNDNDTGVAHGRNGDSNADGIYRPPRVAPMPYMPQTSAKTKRQQRAPIPTSLASVLHTDGSMPHVESTSGLGNTPSLNNTSSRAKYLKHLTEFEEEQFGRVMMGKKEARRRVRDEEALALGGGLSGLGEEGKGRRQRTAGGWEDEFGDVLRDVERGSGRGLGGDGYDELRQRSKRSGVLQRSRENKKRTADSVVADADVPQKRKKSRFERERKGIKVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEU4</accession>
    <name>A0ABQ8VEU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_366820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="21502" checksum="564F6C168660B39C" modified="2025-10-08" version="1">MFIGIVISELILTLRTYAVWERKRSILIILIILTVVFLVPAIVFTQLAVSSLRFLSHGGCRMTSASNIIFLAFCLLTIYESILAILIAIQACKHLRQTRSPWVTKLYKDGIMFYVYLLILSCANIVSCLLAPALGPWLQAPQRVVHSVLCTRVLFLIFQRNFPSIRATMVSEEQELPVATLTELLELEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEX6</accession>
    <name>A0ABQ8VEX6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_369295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045671611" evidence="1">
        <location>
            <begin position="27"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="172" mass="18943" checksum="00C06294C16D4EFB" modified="2025-10-08" version="1">MRCTQPYGISLCVVLGIFRLVCVALGSPIQNPSSLQVETAKPSTSPNIIVQFHGTQPVDEGVMQIARVNVQTLLHLSARKISGTPDLTVHEWRGNPQFSAEYKHVTFLVIVTGLGKEDSGGYTGYYIYTGVPKPYQLNDMKWVERVMTAKLIDPHGNTVLELPCAETSQEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF32</accession>
    <name>A0ABQ8VF32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Ion transport protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_832679</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="3" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="706"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="843"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="897"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="974"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1220"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1264"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1297"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1349"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1474"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1554"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1588"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1619"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1672"/>
            <end position="1697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1717"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1765"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="502"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="780"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="1218"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="1553"/>
            <end position="1799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2020"/>
            <end position="2056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2081"/>
            <end position="2151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="2038"/>
            <end position="2053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="2081"/>
            <end position="2102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="2112"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="2122"/>
            <end position="2132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4492257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2202" mass="246261" checksum="95137D61BC215F39" modified="2025-10-08" version="1">MDSQDKYLRRSSSSSAIDLTRTPAGIASSAPPSPSLEPSNNNSRRRTSWGKVDLGQDPLQLDTQPGATNSAHYTVHDDPFQDSPTDDRSFAPIPFATTTQYDAQPEEDYTLSYYTTAHAGPSTTSLLDMDGTREDDQARLTTNMSRNPTERWREEFGETDMERTAGALSPRAKRRTVRYNTSPSPLKKTGSALKTVSKSLRRASLRVVNFGNSALETQVRLPDDDSEKNEETADDELLPDLSARLPIRGRTLCFLGPRNKLRLWLYSWLIYPWTEPIILLLIIVNAVVLTLQASHSLTLPDGANVGDTLPPHVTGYFHEWEDYVLFVLFVLFTLEAFARICVSGFILDPDISASTFFTSPLASPADISMASQSSSTNNTFPRQLTLASNVGGPLSRGLSITERFNRLNRNLKRPFELPSSNNVTPEPQNHNPSISQTIPVNPVTEKIKHVAQASHSVLRDPPQPTFFSSVLRSDRKDLQETLSLPFKLSINQSHNKTMRSVPYLRQSWGRIDFVAILGFWTSFILAMLGLEDGAHHIGVFRALSVIRTARLLTITSGTTTIMHSLKTARPLLANVALFVLFAMILFSVIGIQSFKGSLRRNCFLLPVNGETQQQLSNQFCGGHINDTTLVANPYVLLNGSVSEYTAKGYICPLGQICQETENPEGNIESFDTIYYAALQIVVTASANSWSGLMYNIIDAEYFVSSLFFIVCVIVLNFWLINLFVAVITNTFSAIRSETQKSAFGAASLPVIEDERDDGWAAIDRNKPVKKNIAKTIYDYTRWCWVLLALASLTLQATRTASVSSTHAEILSFGELSITFAFDLEIVVRMLATLPDWRSFFVRAQNWLDVILAVGSSIIQIPVIKDSTVYSWFTIFQLIRFYRVILEVPRMKPLLLSVFGNMYGLTNMSLFLILVNFLAALVSSQLLRGDMSSNDAVNFGQLYNAFLAVYQVFSSENWTDVLYNAGQAELQLGQTVLVVLFISLWLLFANFIVLQMFIAVINENFDVAEEQKRSQQATHYWSTHQVQAGKATWVRRLNPYRWFKANPVKVQVENLPSSLVLPMQQALVQDYTSGTDSRPIDNKAVRGTAGAKPMQHYTTKSLSALQKLFGGDERADDVPLATLKHNRSETLGALGDEETERHLELLASVNPEAVNSNDLNDALFERRAQKADFIRDHPTYDKTFWIFSQKDPIRRFCQRLVQPAHGERIFGVPTSHVAHPIFQVIIFLAVIGGIVTEIIATPVYRRNYYATNGRIRGAWFDLTEATFGFVLLLEFIIKIIADGFLFTPNAYIRSIWNVIDFVILSGILVNVTTGLIFIGGLSRFTRSLKALRALRLITLFDRMRNSFQSLIISGASRIFDAALLAILYMVPYAVWGLNIFAGKLNTCNDSNAAGMDDCTNEYVNSYINDAFGYPVPRVWDNPAPSTKFSFDNFGSSLLILFEIVSLEGWVDVMQAAASAVGDGLQPQTNASQWNALFFLIYNLLGGVVILTLFVSIIIGNFKSRTGTALLTQPQREWIDLQKLFKRQRPSKRPQRRPVSGPRAWCFDRAVHKHGWWSRCMTVLFTVHVIVLMTQTYTSTTISESMRNDFFLTIIFIYLIDVSVRLYGLGWKSFRANGWNLFDILVTMGSFATTFIARFGNIGFLEQQLQKLFLVLVAFKLVQRTNSLNKLFKTAIASLPSILTLLLLWLILFMFFAILDVEVFGLTKWQTGEDRGRNYSSISSALVMLAFMSTGEGWNQYMHDYALVYPRCSNSSNQDVDSDCGSFGWAFTLFIAWNLLSMYIFVNLFTGVVVDSFSYVFQASGGSRAITREEMRAFKKVWAEFANPQTGYLERSQFVPFFGKLSGVFEVRIYPAQYNIHNIAAACKASPSDNSTSTLTNIQSWSNLSSNVIEGLDIDKLNNVLDGIDYATIRKRRAVYNRLYHEATIAHQQGRGISFTDMLLLLAHHKLIKDSDALVLRDLVIRTETNKLVTDLVNLDRVQSLLKMISLRRRFLAHMERKRASMYDPDIPAIVVDTMPETPPPFPSPSFSPSRPSSRDISTVGFSGWDNSAPSTPTPVRRTNFGSVQLDFGALGFGGSQFAQQQQSFPSLSSRDSFSPSHSPNTSLTLPAGVGIGGAGAGGSSSPRRSVVGAGATGLHRSNRRTSDMSQISRLSTDLGYRYPRDSMGDEDPSLVLEGMQNSIWGDLMAEAMDEEDGRDKSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF34</accession>
    <name>A0ABQ8VF34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_765897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="344" mass="39525" checksum="70732861620F07BB" modified="2025-10-08" version="1" fragment="single">QRSLLGPMFSRRAVLALESTIQNQIDQLISLIEEHYVSPHISIPMSMAYRSITTDIITEHCFANSANTLTPNFDHPIQIGVRDLIKRFWIQRHFPSLNSLVSKAPPKLVRWLFPRYRSYIDMKSKYEKQIDGLLENSDSLSTVDHETIYHHLLNPKVEVLPSRETLVHEAFTLVAAGSDTVGNVCTVGTFYALKIQNIRHKLIEELREVWPDQDSPMSYAVLEKLPYLTAFIKEALRFSLGVVHPLPRMTGPTTMKIAGHDIPPGTIVEMSIVFMHMNPDVFHDPYTFNPDRWLAADTTKMMLDLAPFSKGPRIWFSLAWCELYLIFGNIFRKLDMTLLESEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF39</accession>
    <name>A0ABQ8VF39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_375499</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="36"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="682"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="791"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="543"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="156"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4491715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="842" mass="92185" checksum="A9D7CF535A3EB8D3" modified="2025-10-08" version="1">MPAPAPFPSPFPALYLYPINDSFIPKHISLLHNTHVKIGRQTNAKTTPGERNGYFDSKVLSRQHAEVWEEGNKIFIKDVKSSNGTFINGERLSPEGLESDPYELKSDDNVEFGIDIIGEDNKTIVHHKVAARVMCILSEQDAQIAARAEQYQMQQMQQFAGPSSSLSPASNGSMVNQTGPSSGPGSSNSASFNFSGQQPPRRPQMSQQGISGMGGMGGSMRPPGKSGLTFDHILNRLQGELQKSRETGAELHTLTGAMSDIHETLGGGNLPTTAPPFPHALPPVRPPQSAAPPPSQPDVPSVPSAQDQQDSMSNEPLATSTTTTHFQMSSASSSALLVELQTQLKDTQTSLSQHIDKIRVLEDALKEQETIRHEVRLLRDMMDAVQRHDEPSQNTTSHKTRRQSNVEPQGGFDVDEEEETDAFDDEFEDDSRSVGTAVPHELERVDEEDEESASTVDDESLPSQVDELDLEMAVREEARLQPSAPDGTFDGEFEDNEVEEEQQPQELGRPRTPEPSHLGMSTSRSKALNSPLKHSQGLSSSVVDELTTRLTTLSAQLESALALSSTLQAQHSTAQSTISALESKVEALESLVTATLSAQQRQPAVTTEEQTAPQRAEHESLISMVVEWKKSVEGQWSNVQEEWNQERERLNRAREEWESKVRLVDDGLERLERMQNIALSKDTPFFHGNGDIKHGLVTPPSPRSLSSDSNRPRRKRSGSGRGRTGSKRRSLSRGAETDDTEATLANEEPHVFEKAASKLIASTQTNHHSELTSGSPLAVSELSANPFVRSDHAENSLVPGRTTKAPSINDHNNRVNMQTVVGVLVLSVAAAAVVWRTKPDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF65</accession>
    <name>A0ABQ8VF65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_981250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="456" mass="50757" checksum="B7F5DDA054C7FBA7" modified="2025-10-08" version="1">MHQLLDQYIHSVAGFHPTDSESPEKSFFGVVELPALAFGFEKLDERMREKVKTIAHEYLFTSKLETYLGTDERSYIELGLARISGYDGQKSIKIDEPLVLLSCSIWFNEQRPHTVYKTLADHIQKHDPTTGRNGFKEFIAFYLLKVFEKSRQLNHVFDFEGAADNGLGDREARLVTLHVDESGRKPKVVEGEVSLSKGASSLFGPIGLAIGSDNHSVLNEWMNLRRRATFCFPMNLMGPDIMCFLKLKGKRLRKFTYVCLAIQCKFFRAETLRPCTLRGAIATVTPGKFFEGDPSSDHAMNQKRILNALQNLKSKDSAAGKYGIVHVICGFPVHVNLGKAFPIAVNTKSGNKRQQVITKDPDCHESASAPLLLRFCSASAPLLLRFCSASTTLLSRSASLLCLVTPPLPLCDTDQDNDHPLGKLRMSLLISTTGNEHPTDILEVIRQSALNAKGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF79</accession>
    <name>A0ABQ8VF79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lysine decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_364824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="26319" checksum="6E6117836EE40E8A" modified="2025-10-08" version="1">MNSEERIRAVAVYCGSSIGKRAAYAKAAHSVGVALAKSNRPLIYGGGALGHGLMGTVAHAVVEAGGKVTGVTPYALVAAGGEGDKSIEPNGIKRRVALPTSSSNNIETIIVNSMHERKVEMAKRACGFVALPGGFGTFEEFFEVTTWTQIGIHDKPVVLLNVLNYYEPIRNMIQSAIEEGFVQSFSSRLITIVDGPEDLAQHETYDWGFAALRAIESWKEGEVLTNYDWTKRIDGTRAEGSLAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFL8</accession>
    <name>A0ABQ8VFL8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_769996</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46297:SF2">
        <property type="entry name" value="TUDOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46297">
        <property type="entry name" value="ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="5">
        <location>
            <begin position="71"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="236" mass="25664" checksum="A16CD902CAC7963B" modified="2025-10-08" version="1">MDRTDLETYQVQLSQVDTALQAEPANAELASLRAELQELIALTQTALAQAAEGSSSKVESSRKTASVPSLAWSAGDECMAKYSADGAWYPARITSVAGSEQNRVYTVMFKGYNSTEQAKPSDLKPLPVSYTSTVSATKRKHETDDEKERKKKKNEKKLETRAAKAKEQNHKQATWQKFAKKSEKKGVHIAGVSGTSIFKTPDNPLGKVGVTGSGKGMTQVTLLGKHKFAPTEDDNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFM2</accession>
    <name>A0ABQ8VFM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_407023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="384" mass="42410" checksum="2073B9EFE876C6B7" modified="2025-10-08" version="1">MSASVSFDSQPSLFQPTKVGRMNLSHRIVLAPLTRFRITISHAPIPEVVREYYSQRASTPGTLLITEAAVVSPQAGGFPHVPGLWSDEHIQGWKEVADAVHAKGCYIFFQIVAIGRGANLESLHDHDPSFEVVSAGDIPEPVVESTSGPQFAGTIPRPLTKPEIDQYVKMFAETASNAVYKAGFDGVEIHGANGHLIEQFLREGSNNRTDEYGGSIENRAKFLLEVVEGVSKAVGEDRTSLRITPWLHDRGLAMKHPIPLFSYVVAELKKRFPNLAYLHAVEPRVSVIDDRTPDADESNDFIKALWCPRPLILAGGFLRDNAVQAAETDGVLVAFGRRYIANPDLPYRLMKNIPLNSYDRSTFYLMGDATGRGYTDYPFAKANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG94</accession>
    <name>A0ABQ8VG94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde/histidinol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_981127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="249" mass="27303" checksum="3CCAF282A5FC905E" modified="2025-10-08" version="1">MPFSATNSRNAGKTSFNAGLYINGKFVEGSDKNTINVINPATGKIIRKVAEATFKDVDVAGDQDYWQKSLNLWKELTALEALDSGKSFTWVIDVDTTFAIDTICYYAGWADKIHGQVVEIIPWNFPKLMMSWKLGPALAPGNCIVMKPSESTPLPAIHMSKLIHDARFPPRTFNFLTGYGDIVGAAISSHMKIDKVAFTGSTLVGRKIMEVTAKSNLKDITLELGGKSWNITFNDADVDQVVSWAAHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGA5</accession>
    <name>A0ABQ8VGA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_839205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="71" mass="8214" checksum="802DB36857EEB984" modified="2025-10-08" version="1">MYRYLTLFSALSPSQEQSNILQSRNSHGAKAEECRVYPGVWGFWTLAMRYYTAESLRTSSIARCIQRIECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGM7</accession>
    <name>A0ABQ8VGM7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_830970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046693233" evidence="1">
        <location>
            <begin position="29"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="24735" checksum="B254CA701E2E6550" modified="2025-10-08" version="1">MYPMSMVHLFLLWAGLLSSSFLQVGVVAIPMPNTSVSLEPRASRTLDNIQILLNRGRGPTAKQSWSLFVGYDRGYRTNIDLSAVEAVLSSSGARQSLTRVKDEDRIGQISFETKLGKQIVFDSLFQVQCGEKCSTRLFWIIHALEELRQSPHITSFQFLETRWLDAAEKMIESRGTADGRSVVGTPAEEEYKKLETTLNALRGHITVEEFQDIALGKVVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGT8</accession>
    <name>A0ABQ8VGT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Emp24/gp25L/p24 family/GOLD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_830033</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046772171" evidence="10">
        <location>
            <begin position="23"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="32"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4494158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="25018" checksum="E89DD1ACEF5D8E51" modified="2025-10-08" version="1">MAFKHTPSLVLLLLCSALAANALHFYLDANEKRCFIEELPTDTVVEGHYKALEWSEKQQSYISDENLGIHVEVEEVETGHTVVKSKGPSEGKFTFTSHDAGDHSICLSTNYTSWFSSTHIRLYLDIVVGTTRPDSEHDRTHVSEIAAKVRDLNQKLEDIRREQQYQREREADYRDLSEMTNSRAVWYSVVQIVVLIVTCVWQLRHLKNFFEDRKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHE8</accession>
    <name>A0ABQ8VHE8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pescadillo homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Nucleolar protein 7 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NOP7</name>
        <name evidence="7" type="ORF">C8R41DRAFT_794609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pescadillo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17709">
        <property type="entry name" value="BRCT_pescadillo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03028">
        <property type="entry name" value="Pescadillo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010613">
        <property type="entry name" value="PES"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221">
        <property type="entry name" value="PESCADILLO - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221:SF6">
        <property type="entry name" value="PESCADILLO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06732">
        <property type="entry name" value="Pescadillo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="358"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="582"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="606"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="619" mass="69381" checksum="09A49D9D4F17BEB9" modified="2025-10-08" version="1">MGRLRQKGNAGAAKAYVTRSIAIKKLQCSLADFRRLCILKGIFPREPKSRKRANKGSSAPTSFYYAKDIAYLAHEPVLKKLREHKAFAKKLSRALGRGEWSSAKSLEENKPVYKLDHIIKERYPTFIDALRDIDDALCMIFLFASLPSNPRIPPSLVENCSRLAAEWQLYIMRSHSLRKAFLSIKGVYYQAEVMDQTITWLVPYQFTQNIPVDVDVRVMLTFLELYQTLLGFVFFKLYTDVGLVYPPPLDAKRDESAAGVGAYLLQEASQKSDKPAVTKVKVVEVEGRQVSGRDVYKTIKNIASSSPNADDMDVDAPTIENNFGETEEEFIVQPSKSDAEMASSLPTLQSLKALPQSINTSLFAPYTFWLSRETSRPIFEFLVRSFGGKIGWPASSGGGSPLDESDDSITHVIIDRPVIEQPSETDEQRELRLKRRYVQPQWVVDSINAGKILLEAPYAQGQSLPPHLSPFGEYEGAYDPAELANEELAADEDESEIEGEDVEIEDADIENEALQAVATAATEDSATLRAAELAAEAAGIDPSTFEKEVAKSRRKSKKSSSNGVDEAETDMNKMMMSNKQKKLYEKVKHSQDKRNLERSKLEEKKKNLHKQKRKLGQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIC0</accession>
    <name>A0ABQ8VIC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2OGFeDO JBP1/TET oxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_762876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="29830" checksum="2D13753C6360B663" modified="2025-10-08" version="1" fragment="single">VLAGQPGFDYAEDLLEAFRLFSDAGKEAQLGAADPKGPHKRGEFPAFNRGATMGIGSRTPVAINTGYMTGILNRLVGEKAVRRMAAYQNAAFSLWAPRMHAEYKTVHDTLRNQLPHLPVNFPGVSEFCATAFNLGGNVWTFKHHDFRNWPFGWCAITALGEFDPSRSAQLVLWELKPVINFPPGATVLIPSAVITHSNTPVAEGDSRMSFTQYSAGPIFRWVKNGCRTEKEMQKDDPKGWAEMEAGKDSFYIQCLENFSTIDELLASIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIG0</accession>
    <name>A0ABQ8VIG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_763199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="54" mass="6088" checksum="C9FAED219B09D0D3" modified="2025-10-08" version="1" fragment="single">VHGSLARAGKVKSQTPKVDAQEKKKTPKGRAKKRILYNRRFVNVTTLPGGKRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIL9</accession>
    <name>A0ABQ8VIL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_793988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="48001" checksum="965130775F359C87" modified="2025-10-08" version="1">MWSSLPTEMKLAVVDVLDMDDVKSLSQVDRDTYTACLPSSFKNVKLNNLQALQSFVDNVPRSYCRYVHYLDLCTESNTRSSDPRSITEVVISILAASPCLEELVLRTGGSLHHSIISCFGHLSKLERISIHNSGPEDLKPLSERLVVAIAASVPNLKRLSLDRVSRSLMHAPELHGVPPYVPLVAGDDNIPDHPRLGADLYLPSLLQLPTLRELVIRDTHLGDRRWATVPVKCKLQVVDLGSCFHENEDFNSICIQRIMGAVGKTVDEFSLTTTVSDIVFAKPSVTPLQRLRKLHISPFFPVDSVVDTITNLAGSPIENLSMQCYEDDVVDVCVALEEFLNRRVERGVGFYEKLARIDVSVTSNDASSPLGPDEVAECKEAEQRLKELCCDLRLASRFSRTIPPSAASRLARSTGLVMTRLPAPGDGRVRSMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIN1</accession>
    <name>A0ABQ8VIN1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TERF2-interacting telomeric protein 1 Myb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_335303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11655">
        <property type="entry name" value="rap1_myb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015010">
        <property type="entry name" value="TERF2IP_Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08914">
        <property type="entry name" value="Myb_Rap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TERF2-interacting telomeric protein 1 Myb" evidence="2">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="507" mass="57251" checksum="CB708C813488E355" modified="2025-10-08" version="1">MAPGGRTAFSPREDAHLVEYLAECNQGRKGNKLYHQLVDNLELFPWARRHSWQAWRHRYMRESADFDRRIDLQQKRNLSTLFRNTQNEESTSRDLPQAQEHLDQSAAHRPQRQKRKETPEREINVQVKRRRIDASEHTVPTNGRDLQEGFEAQDMARRVRLGEGSSRLPTEKHVLLDRSRKPSPQLVQQRTLSSESSSESNKMSLSPSNTSTSNSTDLISAAEPVRNTSEPNLSPTPAKSLTKVQQSFSSLSLSWLSMIDQSRLVDMMVEILFDKYKFPPEYVLRVWKQAGDLEEAEAILKQLRDLENGLLRESSSRRSSHTSSNTSSGDGRKEGDQITAEPIMGGPQRASYAGGDSSIVRNPSRLRESFSGDFLKPEERATATETRATFSFPRALDARHDFANSSSFKINVTTPATYQSRVPDDTSTSPKSTKSSTTRDSSDNQSEAHTSNPSDVEAALPPKLPMIYSAISSPDRKMVLQKFWKAYGTDFIQVESTLNDNLPAFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJC0</accession>
    <name>A0ABQ8VJC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_826723</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavoredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798:SF5">
        <property type="entry name" value="FLAVIN REDUCTASE LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798">
        <property type="entry name" value="FLAVOPROTEIN OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="5">
        <location>
            <begin position="106"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="315" mass="34912" checksum="FD8AE443C9046456" modified="2025-10-08" version="1">MNSDSPLSNSAVPSLDQDTTKYTQELFSSCLEGLPTFEESRYNTSTSDDPAVKYIQPPNPGWKFGEKIESSDLGRKWMEGSKLEDDWEHFDADKEDNRKIYALMISGIQPRPIAFISSVSASGEENIAPFSFFQALSPSPPLIMISAMNAPRIKDTTTNIQATKEFTVNLISLPWIVQANAASIDAPAHVSEWEVAGLTKEPSTHVRAPRVKESAFSMECTFFDKYDIVHPDTGITASTITFGLIKCIHVRKNVLNARGVPDPAKLQTVSRMGDISYGLTTEAFRLPRPSWVADGEVIEKVLDKNRQLDLVGDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK06</accession>
    <name>A0ABQ8VK06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_761651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="914"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="936"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="960"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="994" mass="113660" checksum="D1D199968CC8C209" modified="2025-10-08" version="1">MSNQDSDYFPYPNKLMMLLDLISNLPRLRLSSAHFKLILWLLRNSGVPNVPSYYAFRKMQAELQKTCGHEPQPFKSVMGNYFYVNDPRDAVKRNFANPQVAKHMNYYPEEVEGPISEVWQARCHKEYHPSKHTPMLSMAGKQFYIEEVAMLNDDCLVIPRCWIKQNGVVYADAHQVIIDQDGKWEIQLQPIRIPSEKFKFSYLDIEASLPDHLIPWKDSSLILQMPNPNRKLVPTGYDLYDVFIPLWADDVSGNKSKQYNKHINMYSVNSNLPGQLLHQEYFVQFVSTSPNATSPEQFSALKDMINDTHQHPVICYNAETRRMCGVRLHVPTLPADNPQQAEEACHAGGNANLLCRKCDAGGTYEETESDEGYHALYGVGIARSAAQTREQLTLQLKAATLGVKSEITQMQRATGTKDKVAQYWIDILLEKSIKMKKDNPNMPADEITATLETWLDNQPGDKINPLLDIADLDPTQDTPVEILHTILLGVVKYVWHMFHTSLSIEQKNLFVVRLQSTDLDGLTVPPLRAAYMMQYNNNLIGKHFKTLMQTMSFHVHDMVTPAQFQLIQSVGELGAMLWIHEINDLELYLKDLEIIIGNTLDAFAAVDPAKIINKVKIHLLNHIVPDIRRFGPIIRNSTEVFECFNAIFRMCSVFSNGQAPSHDIACQFAGMDRVKHILSGGYWVHSSGQWVQAGPRVQEILTNQPIIQRHLGWIPKEAIKIGTFHSIKKTQTVLWSTTKAALVLEQDWRFWHNNISVIAKSGDCCKIGSWVAVQKKLSTEFHIGRIAELLSPFSPTTNFASERPDNVIAIEDFILGPIRHPQFNMPVLHKQELGAGYFTVNSSEILFRLSVQHDCRSMHCSATGTQAVIQEHEATERTTHYIEHVDDKHFVINMHSLHNANLIRALLPHNLTEPKPLHSDRERWHHSIAADLRRTQREKRVRTQEKRKRTAKENQRQKEAQQAQMQVVDQDGSNAESEEQEEIFALQPINKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK97</accession>
    <name>A0ABQ8VK97_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="857" mass="95575" checksum="69127F5479E3447E" modified="2025-10-08" version="1">MSLKPSSRNRKQVVGGWQFDALDETRPGRVMPELPRELWIEILAMASCQYLGKASGLVGSGGKYDSLPRTANGRPLGAKSDILSFSLVSKAWNTYSQPALYHTINIRRSSQAKALAWTLLSQICGGPPPAQTLLIPSYSPQPMSYSASCSSVGSSSVTPSTGLETSGRHIRYLTLSTFSYDRCDPSDVLVILSSSPHLVGFCDEGGIRCPLLDDCCDWKATPEKLLGVLVAASAQDKEKGRKSRRESKRYSNGTISAPYSSNTARLECLTWTCYPHLPLPLPIPFSPSGEFTGFNLLRSLHLYLPYNDGMESFSFPEYPELDGSINTKYQPPLHLPSLTKLTLTLSDPILSKSHKGSTGYTYSTPPNTLLALLAEWDLPSLRILTINTPYTLHHSSDGRGQNPQQHHDANDAADERLGYKLGDGFWRFFKSHGSRIVVLEFGRISAGSQISPRQTLSPLSRLASRASHIAREGYVEGSEAPGYGYEHSYIRDVQEMEDRWIEAQVRDANREQVEAERLAEAEREREEFESWTKPFPPSPEAAAASSPMSSSFSSMSASSQNLASLTPNLRTFICSASLSSSHDQDLTFNGLDAFDDAADAFDALEWDWTHPDWVAPHPLLPSHPNVRMIGIREIGERVRADWDEREEGVIWDQSELGSENGMGDHNNPFFMLYLQLSSLLLPSVDDAEHPDEVQGSSIRRERQKVPFPSLKYIRDLDPDSDLLRRGVRHLERTSIPSVMGPMQGAGSPVMSQAHARRWSWRRPSLLSLPSFLPSPSYASQFSNIISARNSSRPPHFNLYSVQTQTRSRHQNASDASHSALLTLWSRVLFATRGGEVWLEDWRGWNLTKNNLERWKRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKQ3</accession>
    <name>A0ABQ8VKQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_241204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="53862" checksum="DCA9C0C8607BD2F5" modified="2025-10-08" version="1">MERGNTHHGTTYTNDFILPHSHVGITDNLPQTNSGTNRSSLSSTLSRLVQQCWLLLFFRLPALYHSQMLEVATSSGIGTADLHLMSTTFSALWRHELPPSLVAKNNVIAISPHLVQFKASWELLVDDLLQEWKMFNLISALVQTSISVLLSLDNQAGSDPITRTGVLLSFTCAGISLLCGSFCVLQFGSMRRMPKAAKWMQEAHKSDQLVWWNCWIMLAIPATWLAWSISLLMATIMTYTWRNTTQNGVSSTIELSAHAVLSLRITVTAVLAFGVVCIGALVITLSLQFGDHLDQNSVLRAFDKRDARSPKLEEYRHESEQPRTSPSVSFPVTTFHSCDPLPLTSAGIPHMPFPTTKLMDANSILPLSLWLPRYIQYQNQCFSPWDPFVNELQNVIHQVTLIPSLLISLTCYPRFSNIHLHRVQRMSLLHALSVGTCKFSGQIIWKQSCAWNFLSNLKCRMKTCRHLRTIAALAAEGLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL06</accession>
    <name>A0ABQ8VL06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_760607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051806">
        <property type="entry name" value="HAD-like_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481">
        <property type="entry name" value="FRUCTOSE-1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481:SF2">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="344" mass="37121" checksum="263569883250F559" modified="2025-10-08" version="1">MPSSFHADAVLFDMDGTLTDSIAAVEAAWGKVAKDLGQDPAYVIAATHGKRAIDNLAQFKPQILPHQMESEVQNFEESILFFADAFQIHGPGSRRASPVTLNSDSAIDSEAATPSLTPGSSATSSRASSFVFDSSRRPSFVGRLSSALMMSAVPEAEIVDQYDPDFEDPCMVEDHLSVVEDQWIEKSKIHQLEAWQIEAAAVDRSVRILPGVKKMIDSIPAGRYAVATSGAKTYAYGCMTRVGIIPPPVTITADDKRLKAGKPAPDPFLLAANCLGYDPKKCVVFEDSPSGIRAGVASGATVIAVCTSHERSKIENCGAHFVIENMEKVKCEMVDEQLHFTILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLE5</accession>
    <name>A0ABQ8VLE5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein N-terminal glutamine amidohydrolase</fullName>
            <ecNumber evidence="3 8">3.5.1.122</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 8">Protein NH2-terminal glutamine deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_895221</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:50680"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="Rhea" id="RHEA-COMP:12777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:64722"/>
            <dbReference type="EC" id="3.5.1.122"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NTAQ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.122" evidence="3 8"/>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.10">
        <property type="entry name" value="Protein N-terminal glutamine amidohydrolase, alpha beta roll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037132">
        <property type="entry name" value="N_Gln_amidohydro_ab_roll_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039733">
        <property type="entry name" value="NTAQ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023128">
        <property type="entry name" value="Prot_N_Gln_amidohydro_ab_roll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035:SF0">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09764">
        <property type="entry name" value="Nt_Gln_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein N-terminal glutamine amidohydrolase alpha beta roll" evidence="9">
        <location>
            <begin position="14"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4495624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12974" checksum="B52849F7A23B0424" modified="2025-10-08" version="1">MFLKPPELPQDAAYTSHWCEENVYLLIQSFSRDSSLSEDWDVFAVFISNHSKTVALWNQKLSEELGCPVIWDYHVVAVLRSRNISTSVQSWVYDFDTRLGIPVTFDSKLKGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLH7</accession>
    <name>A0ABQ8VLH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_221621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="28960" checksum="F6DDFA4717EDA7A8" modified="2025-10-08" version="1">MTLITPFSFSFMQLLFPLIKFYFTFVLFLAPTMAVPTGPPNAGESLSMTGALSTSNPDLPDHSTGVDNNAYDQVLHATDVNTGQNPIIEARLWIHHDVFSHTPDYRTAMGYAVEYIINPIQSTILKDIRKDNPSLTLPSPTRVLVYRLSGKDFTNQGDFEISFSGVAGADSTLPENWWFAMPGSVDPSYFGHVDLKCLVRTLKGGYTFKKELVTGKISRRYPGKNEEVLVSFKNGKATKSMKSSTLSRVKTLFGKKPGGASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLV2</accession>
    <name>A0ABQ8VLV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="1">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="140" mass="16643" checksum="B8D89B104A0CE42D" modified="2025-10-08" version="1">MARRRTHQLQSLYRQRISRLISPSDGPGWIYVYIDNGNEFKIGMMKNFERRQREWDRNCPCLDRIWFKPILAANRRRAESVVHILLEIQLSGTRREICFCWSSQGYSEEDLGSSVAEGSDDLKFILRYDRLSILYNSDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM71</accession>
    <name>A0ABQ8VM71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_309939</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="103" mass="11059" checksum="117946C592513345" modified="2025-10-08" version="1">MTVGKISAQCGHATLACYKTLTKKNPKLVRHWERTGQAKIALKGTSEEQLLELEAIAKSLNLCARSIIDAGRTQVEPGTRTVLAIGPAPVPLINQVTGSLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMG0</accession>
    <name>A0ABQ8VMG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_866417</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003764">
        <property type="entry name" value="PRK05355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247:SF1">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="11">
        <location>
            <begin position="8"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4495641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="403" mass="43462" checksum="25970F25DA0BF81D" modified="2025-10-08" version="1">MTEARPVNFGAGPSALPESVLEEACKGLFNFKGTGIGVAEISHRSKEFTSLVADLEDNIRTQLGVPPTHKIIFTQGGGTGQFSAVVLNLLARHRLLHPDLSDEQRVLDYVITGSWSKKAMEEAKRLGGGSVHIAVDARAKSKDSKSFDNIPAHEDFDFSADPALIYYCENETVDGVQFSDDVQSPASFPFHLLPAGGLWPLVADYSSSFMSRKIPRIADHAVIFAGAQKNIGPAGLTILIVRQDCIVDVDAAAKLGAVPVPITMSYKTNADAGSLYNTPSTLSIYIAGLVLERSKKLGGVEYFESVNGRKAQKVYTALQEGEAKGVYRSKVKEGSGSWMNVVFDVLGDNAESKFLAGAEALGMKALKGHRSVGGIRISLYNAITEEQTDRIVEYLKDFPTQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMG4</accession>
    <name>A0ABQ8VMG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucan 1,4-alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_731728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="8861" checksum="920669D81FA03F14" modified="2025-10-08" version="1" fragment="single">LSALLAKATSNQTYLIAAQTSAAFIKAHLYNTDSVVQDTISARENDSCSTSGNMWPYNAGLMIEGLATLYSFTQNATMQSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMK4</accession>
    <name>A0ABQ8VMK4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_909519</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4496439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="512" mass="57744" checksum="E835DFF36805225C" modified="2025-10-08" version="1">MTFAVGDFVLLTLLACFTSYRLFFSRKYPHSLPPGPKGWPLIGNAFDMPKTHSWRTFAQWGKKWGPIMSVKVLGTPFIIISNPDIADEMLGKTGSLYADRPTVQMALLTGWDRALSGARYNARFREYRKLIGKVIGTKGSMAKFYPVEDFQANMLLKRIFQNPEDPAAAIRKTAGAMVLHLTYGYKISEDRPDHFITKAEFAMEQFSDIHRTGAYLVEFFPILKYIPAWFPFTEFKRKAVECIGPCNEMADVPFAYVEEQLGKGEENNSFAADLLKDRSISSEKLTDLKWSAASFYAAGSDTTVSVVYSYLMAAVLYPRVQRMAQAEVDSVVGKDRLPSFHDRESLPYIEALVKELYRWLPIVPLAVPHRARKDNVFQGYYIPKDSLVFVNVWHFLHDPAVYKNPSSFNPERFLGPDAEPNPIDRGLFGYGRRVCPGAHLADVSVWINIVKAVAGIEVSPAVDEKGQAKMPVPKTTDGIIVRPIPFECLVKPRSEHLLHVLEEALKDGEKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN92</accession>
    <name>A0ABQ8VN92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Origin recognition complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_881587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25420" checksum="2325082D9628B6D2" modified="2025-10-08" version="1" fragment="single">MKNGSTKFRWGGQAKAVSGACLAVALRESNKPDRLKEIALLLGQKYSYLQRTLATLLASINLKFPPTTPSHHIPNLLSHLFQELKRLPEETILNLKLYSQLKALSLQAVADLSCAFLETFAMTSKSNFIQSSPSSCAVSAFVICLEGELGKSLSEIKDLYKCFSQVCHLSAGTLARPYRSMCQEVLKWMEDLNWVEQYKKNTTGRADSSLRNVCARGLKDALREIDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNJ5</accession>
    <name>A0ABQ8VNJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RmlD-like substrate binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_822353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="299" mass="32984" checksum="7A6F04AFDBF8A36E" modified="2025-10-08" version="1">MKVIITGASGVLGSAVREAFKSTPHQVLALSNTRTGDGLVPLDLTNTQEVEKVFTEYKPNWVIHCAAERRPDVAEKDPQGAQKLNVNVSGHLASLAKSLKYTLVYISTDYVFDGNSPPYTPSAKTNPLQLYGRTKRDGEEAVLSVDGAKVIVLRVPVLYGPAPKNSDSAVNILLDVVQDQSGKQYKMDHYATRYPTNVVDIANFLVRLSEFKKTATVPPILHYSAAEPFTKYEMCLVFAKILNLPHGHIVPDSEAPKGDSATTRPKDCQLYTKETEDLGVEGGLGLSLFEEWWTEYLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNR3</accession>
    <name>A0ABQ8VNR3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_820598</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13329">
        <property type="entry name" value="ATG2_CAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="629"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="727"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="969"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1542"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1542"/>
            <end position="1552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4498035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1998" mass="219818" checksum="1A33E5D55DBF9353" modified="2025-10-08" version="1">MSWFSSWLPSLPSISSFAVPSSIQRRFISFVLKRSLGHLLKPGQLDIEQIDSQIGSGYVQVNDLQLDNNAINSIISQSGLPLELVDSSLASVTARIPWPNPLTSTLGFSLSSLHVTLRVIPVQESTNHTDINLSESVASYAESFIQDELTPREEANLRESFRYDPSASLHHEPDDGNVPGGLNPFRDLSEEEELADMDPDGVSLFATLIERLLAKFEFDATDTKVTILHPQSSRLSLSIADINYRTEAPSNADNTDGIERTGESRTVSISGITLSGYDLRPHSAVPFSPDRLSFEGTPSYALTPRSPSPSSSSSSSSMDEQAQWAMSQSLAFLPPRPGSPASSVASSMYQSAVSGHALYAEHTGRTEESSSSPVSGSKHDLDHAKEADDEVFLSLGVDPTIIKLTTPSLRGRTPSQTVLEELHISMDIGIISCALRPWHVPSVVRLLDAIMLSRVSLTPTPSNASTSQFSLGTDKRLSLNVKAVVVLLLASSSNGASSPFALGGYFSRPRVPPSLSEGYLRLFLDNLSATASNVTMNSKARKPESGSGSRTSTLTFSLSLNEISVFASRLSNNNNEAEVLAFPLMITDPLLPSQHISEHKHPDLSSEFPILLDFDVMDWTTEAACKHGMRPSAWRTKQKQNKASHSSHAPPPATDRDSLIPVLTVKGEWQSLEKPPHKGKSMKNDIRAEFSPLQFFVDLRHLLGATSINSYVDELMSALKSPGATKLETEMDGSDSHNDGDTPPATPRVNRYHNIPAEHEEERRNLEDLVLQDLDLDLDYRQIPTSKDFKRSGTAKPVTRRSQKKGPNVVVRFPFIRTNIRCSSNYNQPSRSGAVVVDIQDLALTNRQIPTSRRTASFESPSSTRRLKPAGNVILTSEFRRLVIASSSAGSPKASVVVSLGHLQNEEASDRPESQTLLPRIVLSQFSQAFNSTTTITLSLPSVLVSMDKDSFDALQYWADDASQLVQKSSGYSDSDVDTEKPTSRDSSLIGSHYFAESNTSSEVTSLASNPRELKAIITVQVFVVETFCRIHLPRLAEQPMNIRPFDMMASDIDVSIRIRPEGRDETTATVKLMNLLINDHTGQGNIHTLLSLTKARDLLLSPQPLLKLRFTSVILPETIAKESRIRLHLWGFTYQLFTDVSWISDITLFANAPPGAFETVVPSERTKITLRVVDGSMKVLAPTHPGALVLHIGDLDFSTDLIGESPELEFMLRIHTAALLAIDDLAEFHASPTSAEGFLFWKKCGFVLLSEIMNVVLSFKALKSATAPDTRVVIQNLGLRLHLCADTMSAISVFVSDLITALNPTLEHQTPKPKRKPMVISEEQHNARGIMSSVDNFAFKKLPEIGPAPDMIYDDLPRNPDYLDESFGAAGGLRELREEDLNDFDDEEVFPTPSSDEDINGVVSRLGGETIRILRPEGLQVVESHFDNLPPIAENSPTNMGDTTLHVQVHNADINVFLYDGYDWSTTRRTIENEVKEMRKRLAKIRQLVAKGQTQQTAGEETSALLFNSVYIGLKEDTDELDSNALIAAIDEELKEDLDTATESSWQSLPVPSQPKTPAPAARLNGKRLARAKSPSIEFRIAGLDADITQYRPDDPLVSRVFATLKDLEILDHIKSSTWKKFLTALRSDSRGNVRETDSNMIKAELRTVRPVVNDPSEEARLKAKILPLRLHVDQDALDFLKKFFSFTDPTRPSTPTDSDGGIYFQLAEIFPVDLKLDYKPRRVDYRALKEGKTIELMNFFHFDGAEMTLRHITLSGVTGWPRLGELLNDLWTPDVKATQLVDVISGVAPIRSVVNVGSGIADLVLLPIAQYKKDGRIVRGVQKGTTAFVKSTAIEAIKLGAKLATGTQVILEQAEGVLGPQFKYPITTETLRSPNFGDDLLDIGFGDSSDEEENALDLISKYADQPTNVKEGVQSAYKSLQRNLNSAAQTILAVPMEVYERSGNEGPVRSVIRAVPIAVLKPMIGASEAVSKTLLGLHNTLDPNLRHENDAKYKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNT2</accession>
    <name>A0ABQ8VNT2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription and DNA repair factor IIH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_819201</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01453">
        <property type="entry name" value="vWA_transcription_factor_IIH_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
        <property type="entry name" value="TFIIH_SSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4498064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="446" mass="49455" checksum="7E74D2EEE7225B2F" modified="2025-10-08" version="1">MNVDSDSDISISDYEENEAGVSRSRTKGKKKATDKRKKDKAKRKPKDVQAYTWEANFARSWETVQEDEGGSLQGAVNDWMARGRRKRLLQPQNAIRRTIIRHMVLLIDLSSSMMDRDMRPTRFAVTLQYAREFVLEWFDQNPLGQMAVVGMRAGVGERICDMSGNPQDVLKSISDRHKLEPIGEPSLQNSIEMARNSMNHLPTHSSREILIIFGSLTTCDPGNIHDTLDECVKNRIRISIVALAAEMKICRDLCDKTGGQFGVALNEGHFKDLLFELVPPPAQRALPRSSAAVSSSTNPAADLIMMGFPTRLPDTSPPSFCVCHSELRSKGFLCPRCLAKICDVPTDCDICGLMIVSSPHLARSYHHLFPVKPYSAVASFDNVADPSTSPSCHACSKIFPTTALHNIVDGMSAIGRYRCPDCETDFCSDCDVFVHDVIHCCPGCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP55</accession>
    <name>A0ABQ8VP55_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_819174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="692"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="871"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="885"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="928"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="946"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="969" mass="109341" checksum="362FDD63E24ED9A8" modified="2025-10-08" version="1">MQRPGSYGLTENSMNSHSGLKTLHPSLQSSKHGDDLYKRSFGTKISNRTRACDFCRSRKTRCDGPRKVDNICTNCLQNKKACTYVEASTPRGPPKSYIIGLEDKLEKMEILLQRLRPGQDFSAELGPPVVRDSWKDPKPSSEISPSASRLRVSSPSKLAPHLDSNISIPLSSHLKIHTNPSTSSKMLPYHRTRQGSATNSTDSSSSQYDSSDADELVDNFEKGMQRLTLHSGHSQLQGAGPYDRFHGQSSYIKLVDATRKLRQAHIMAQKEELGHSSGSNTSTTSPSPEISNALRRLEFWRAPKWELVYEGLHVDSPKLLDSVLEQFPEPDLAEELIEHYFLHVNSLLSLLNRQIFLRQWRERLHNKDIWFSALSMCILALGSRWSNDPRVIPRDHTKSRLDWTKAGWDYFNVVISIHRARRSLLCTATLFEVQTFSLVAWYLRGTPDYAVGGTMVTVGIRKAQDVGAHRKAVYERFPTVDEELWKRAFWLLVILDRTGSASLGRPCSLGEEDYDLDLPLEVDDEFWATEDPTLAFQQPSGLPSRVTAFNAWIGITQIVGFALRTLYALDPKKFFLGRRTLPEPEILVKQLNIALDEWFNSLPEFLQWPVTTDDLIFSNQSASLHLSYHFAYILIYRTFIPFSQILPPGIRGVRIPRSSQKPSALSTPALPICVNAAKSCARIIQEQMLRGFSNVAFLITMCNVCTAVLIVHLWDLKAKEISERSIRISTTEDVKPQYALAIQSAKDDIEIFLNALEWAKPHYSSVAQILDDLRASFPHYDSPAADQYISGRQEPSSYLPSSEGSRILWSWDSPEVPSNAPSLSTLSKPDWNNMPPGYSPLRTNSYSIPTASFERNSNPLIRRDSDPYLRQRAFGPTYSNSSSSAQIPSNQHTISDYSAPNRESLPYSSTSSSRHDYSPYDSYRANDELNTSQQLPTSDARSLPPEYDKRGSTRDTGDTAWNGYRPVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPA2</accession>
    <name>A0ABQ8VPA2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_917451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="53"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="491"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="794"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="872"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="623"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="675"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="801"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="886"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1157" mass="125204" checksum="F2627A99D37FAF25" modified="2025-10-08" version="1">MLADNDGALPSPPRAPNVKYSAPHGTRWDKEKAAAGGARAFDLPSDPKVLGPWIIGECVGKGASGRVKIAKHRYTNQLAAVKILPRAPLDSSRNSIATQEAKSKKHSLGIEREITMMKLMNHPNILRIYDVYEGPKELFLVLEYVEGGELFDYLVNRGRLPEPDAICFFKQIIYGLNYAHTFSIIHRDLKPENILISSLSPPKIKIVDWGMAAFAPPTLQLETSCGSPHYASPEIVNGFKYTGNATDIWSCGVILYALLTGRLPFDDKDVKLLLGKVKVGKYDMPSYIDRSAQDLLSKMLVINVEERITIPEILAHPWLNTSPAALRQMSIASSFESRSPLELVLPPSPSTLARPITDPSSIDSDILFSLKVIWGRHADLAAIVKDLGSPAGNGVYTKAFYWLLLRHHEEAERLSGSDETNAENTSANGMGPGSVTFNLGWELDTSGLDGVTVKFPSAAREIKVGRVLGPERRGFADTSLQAADRLLSPLMTREVSSTSSSHTYRSRPNTPGGPRLPTVPRPTYERNSSQYTGSHSGRSSSLPKSSFAMGNGGGSGIRASSVVNGTQGGPRPQPPKRGHTYSHPRPDKPSATTARSNKSPDIINVSTVQFPPTPIHPVQYTQSHRSVSRSSRPRSVTTVDVTTEVSRPHLQARSRSHTSQVRGGYIGGSSLKRATSSVHSGTNSSSGSSTTCSITSTATMHAPIPMKAVSGVFEVPMEVDDDSSMPIASTPPPLLPPHSPVYSLPLLTAPKTNDPTLQMELDEVAEHMNRLSLQNAVAETTTLCQDIQTQLREYHSHTHQSRAQSRQASYQQQRFQSPKRNRRRTVSTVERGARCVDKENKENASVNDESWSYVVPDEGLSIVSGKKNALFADTGNHKRGLGANDGKGKRDKDKKPRPPPLEFTPLNHKRSTTSALGSPIALSPPAMNSTSTKAGLGSPVVGEFKGWLSSLFSWSSKNTSGNYILYSIDDVTKTRRDLLHLLASLGVVVEVNSCETGVERENSPLRCRTEESPSDALAHLGLKPVKFRIELTSIGDEGESSGTFPSSPVTPLSNGHHLFPTAGAPGARGRSSTLGGGSKSPHLPLSPLLSPNYFAGSVHGFLSALIVIQEKGSASTFKAILRKLKDVYDDGCGDTINSNFSPVMTSTPVIEPPRCVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPH8</accession>
    <name>A0ABQ8VPH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_757440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="143"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="337"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="382" mass="39424" checksum="2821C3D0685C9227" modified="2025-10-08" version="1">MKVTVKTTQQKVFNIDAEATESIGAIKAKIEQYQGFAASSQKIIYAGKILTDDKTLESCGFKEKDFLVLMVSKPTPSPMPVITSTPTPAPDVAPVAPAAPTLSGESPATTPTYTESPSASTPVPASVTPTESHAAGSSFLSGSALQTSIQSMVDMGFEREQVMRALRASYNNPERAVEYLMTGIPAHLEAEAAGPAAATSRTPAAVAQATPTAAPAPATPSNQPQNLFQLAQQQQQQGAGAGAGLSAGAAAGAGAGGGQQLDLAALASSPQMQQLRQHLASNPEAIQPLVQSIAAQNPGLAQILASNPEALMNLLGGGDLEGEEGDLPPGAQVVNVTEEERAAIERLEALGFPRQLAIEAYFACDKNEDLAANYLFDMGNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQN6</accession>
    <name>A0ABQ8VQN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_817170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fl(2)d family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033757">
        <property type="entry name" value="WTAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17098">
        <property type="entry name" value="Wtap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="270"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="40373" checksum="8C79D76541B09A54" modified="2025-10-08" version="1">MDVPLPSTRELELEMLLREKEGQVIQLSDEVSRLRLYLSTQPPPSTTEPVTLPPTFASLILPHIPHLPQTSDAAEISNSTTTAALTQRVRVLQDENDELYGILKRGETGRLKEEVQSLKRIVHKLEGALRESHQVIVTLSNELDKSYQAFASSSNNRTASPQNHYHNNGIKPHPRSHSNTGGRLPPTGPRAHSHVHKKQRLSLADQDQHQDEMSPSMRSNVSLPSSAHHPGNNGRRGRSRSRSRSPRGKSNVKMEIDEVQDEPQRGSPQRIRDRERWDRDRERGDRGDRERGGDRDRGRDRDRDGNRSRRNGGGRGGSRRGGGERGDKGSYSLYNASSNFVGSQGNSGSGDRTLAERMGLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQU4</accession>
    <name>A0ABQ8VQU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">chitin deacetylase</fullName>
            <ecNumber evidence="12">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_817611</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF135">
        <property type="entry name" value="CHITIN DEACETYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047167423" description="chitin deacetylase" evidence="15">
        <location>
            <begin position="18"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="16">
        <location>
            <begin position="150"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="381"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4498755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="444" mass="47222" checksum="A6120AEBA87E8A62" modified="2025-10-08" version="1">MLLSSLLPAAFFLSASAASLTHRSATHHEHRILQRLPSNEWFHPRDHPVHQLFRRDADTDGIVYPDVGSSTWAAAYPSSTPDTSQLPAAWTAALNAAVGAGNIPNVPVSSQPVPDTNPVYPDGYDPTGPDVCSGTYKCRIPGNVWDAPDGYIGTGFDDGPTSASPALLDFLEANNETVTHFMIGINIISEPDSFTRSVELGHDIAVHTWTHPYMTTLSNEDVLAQLGWTMQLIHNSTGGRLPKYWRPPYGDTDLRVSAIAKEVFGMETILWNQDTEDWSLTETGGTTAAAINASMTTWLTGSKTPGLIILEHELSDESVQAFEAAYLVMKSNGWNLQSVAQLAVAGQSPYQNALGINDGSVTPADIIIGEISATLSATLSSTTTSSTTSSSAPTKTSSQSATPSQSVASSADNSSNSAFSAWSRLSVGKSVVYGAIISACVIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRE6</accession>
    <name>A0ABQ8VRE6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 5">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_755713</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 5"/>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="180"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="PI-PLC Y-box" evidence="7">
        <location>
            <begin position="540"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="475"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="677" mass="76381" checksum="37FD5AB1DB799485" modified="2025-10-08" version="1">MIHVDNNKTQTQSLPTVPEASQEWARFTKVSDGVIKYPLFRIDPDEGQILYESKKKKGIKIIPIESIKELRFDADSSYYRTLFKLPPDTQSRWITIIYIREGAYKVTHLIAPSASVFKLWKESLTKLYAVRQGLMTGNFDHVLRDVIWEKQYWKTADHDGDQKLEFENVQNLCRRLSLHFSEAELRNLFNAADVHDRGYLNYVEYQELIKLLKKRPEVQTLYEHVSGGKLDFAAFKSFMLHSQESKLDDKGLEVLFTKYSGIDYSNGSTPPSTTTKDLDTRPPDAIMTPEAFATFLRSLDNAAILNQNKVVHHDMTRPMSEYFISSSHNTYLIGNQLVGVSTIEGYIRALLHSCRTVELDIYDGSDEPMVYHGKTLTSKVSVREVCHAIAKYAFASSPYPVVISAEMHCGIQQQDMIVQIMKDAFGDALISAPVEGRAKITSLPSPEDLRGKIMLKVYSSPTLLPTKNLNISSGLRVKKAPPKTAPVDDDSSSSSSSTASSASHVSHSSLLGEIKDLKSKLARKVRSKSRTKHKEMSFALASLLVYTVGVKCRGIGASEHYEPEHVFSISENSANKYLSTSMLDLVKHTQSHIIRIYPKGTRVDSSNYEPHLYWAAGAQVVAINWQTFDLGYMINYAMFQRNGRSGYVLKPLALRPGNESLLQKPTKHYLDLTVRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRK7</accession>
    <name>A0ABQ8VRK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tim17/Tim22/Tim23/Pmp24 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_79706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019531">
        <property type="entry name" value="Pmp4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460:SF3">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF013674">
        <property type="entry name" value="PXMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="23903" checksum="8221067C69919825" modified="2025-10-08" version="1">MDLSSINDFLLNPVFHDYLAILKGARNGFVYGVKVRFPHALVMSILFGRGDVKTRLKVIYRATKQHAFNLAKFVSLYKTLLLLQKKVNGGKERSADTFIAGLIGGFLVFGERTAVNEQIVLYVIARVVASFIPRAGSPYSSSPQSPRATALVKPVPPNPQYFAVLAAVSWGAVMWLFKERGETIQPGMFNSMTYLYRDSEVWKNLKTLLWHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS96</accession>
    <name>A0ABQ8VS96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD/NAD-P-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_893561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF7">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="605" mass="68427" checksum="3363C97FAA432142" modified="2025-10-08" version="1">MSSVEGTSGLNGHTTYSPENKYKLPSFCIDETRPMKVVIIGAGYSGIVAGIRFLQRVKNLELTIYEANAGIGGTWFVNRYPGLACDIPSHCYQLTFAENLDWSSFYAPGPEIQAYLESVVEKFHLGPYIKLQHRLTRAQYDEKTGKWHLTIKRATASTDNSNPQIRQGMAHDEYEDIEVTADVLFTGIGSLSRWHWPEIEGLETFQGKVIHSAQWETGEGDSGAKTKWEDTVKSWGDKRIGVIGVGSSAIQIVPALQPRVKTISNFVRGKTWVSASFVREHLVTLANGDESVDNYTFTDKDKKKFRDKEYYREFRRGLESDLNGAHLATLRGNPLQQGAREIFEKIMRQKLSKKPWIAEHLIPDFSVACRRLTPGPGYLEAFCEENVEFVPENIKRITPTGIETVDDKHRDLDVIVCATGFDTSYKLPFTFIGRDGIDLSKQFEPHPRTYLGIAVDGFPNWFSALGPNTGVGAGSLLIIIERQVDYAVAATLKLQRERLKSIEVKKKAVDDFDAYLESVFGEKCRSWYKVGKEEGRVVSLWPGSCLHCIKALEHPRWEDYDYEYLDPDNNRFFWLGNGNTLADKIPGSDRSWYLSPEEVDIPGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSQ0</accession>
    <name>A0ABQ8VSQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_63557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="114"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="419" mass="45235" checksum="F363FD5A87C9EA26" modified="2025-10-08" version="1">MEIPDPVSAPQDPVHVRRTDEQGRGTVNLPPHDPPTTSDGVFNASEGRKLNREALTKYTQINPNSQNDETSQGTESSVKTGDTADHSSVKIRRGDKSDKKDEEGLTDEEGDVEWAGNIEIGTPKQKFLIDFDTGSSDLWVVDKSCTEGPCAKKKQKYDAGKSKTSKQESGTFSILYGDNSTVSGPIHSDTVTIKGVTAKDQEFSSVTTLSASFADDPTAGILGLAWPKISNLKATPWFLNAVEQGAVKTKEFGFHLSSGKGSELYLGGTNPELYEGSLEYHKVDPSDGFWKVLDASIYVGGKEAGKDFSTIIDSGTTLMYGPPDAVKELFSKVDGAKLYDETEGFYSFPCDKVPEVSFSWGQKGKNSSCVASLAASNLGLGNAWLIGDSYMKGVYSGFRFGMEKIEQDAAVGFAELKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTB9</accession>
    <name>A0ABQ8VTB9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_31322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026505">
        <property type="entry name" value="Solute_c_fam_35_mem_F3/F4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346:SF4">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="41774" checksum="398713FB90AFE87A" modified="2025-10-08" version="1">MVHQRTSGHRKPFVALILALGGFVAQTQLTHRVLTVMNYNRPFFVIYVTQSVFTASVLVHLVYLAITTKSPISSLCKGLKITIAKRLHSSKSLQRIRFPCIRFLLITLTLTAGFTTPTLLWGVGISLSSASDVTVIWNTNAFFAYLISVTVLGHQHQHSKFAAVLLATMGVVLVVYGGAEPGNSVLHHRRLPSRSVGDLFALLASVLYAGYQLFYDGFIELPLTSPQGLDNFSSESTPLMEPEELEEYKDAIYPSPYGLESSFWTSMIGLCTMSLLWAAFPALQSLGIEHFGLPTDPPTVLAILGAAMSGATFMTGTMMLLASWGAVTTSVTTLLTTVLVFLTDLLLGAAISVWSIIGAATIAAAFVMLLLADNSPALVHATQESNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTZ0</accession>
    <name>A0ABQ8VTZ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_813923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="6">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="84"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="142"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="409"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="458"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="531" mass="57473" checksum="46884DDC2EAAA2DC" modified="2025-10-08" version="1">MSRFVRASKYRHVFGQSGKKEYIIENVKVTNNAWDTNIIAASGKYVSINWNASGGGAFAILPLPSPFHTISGFPHKLPDTLPLARSHTASVLDTDWSPHDDSLVASGGDDGKVMIWKVDDSAFEGWGADHWVPKDFDPVWRIDASPRKVGQVLFHPTASNVVAGATGDYTVKLWDLARTEDPRNVLSGHNDAIQSLAFNSTGTLLVTTCRDRKLRLFDPRAGSDAVRVTDGHGGIKGARVVWMGDHDRIATTGFSKMSDRQVAIWETGSLSNLKTTTIDQSSGVMMPFWSENNILFLAGKGDGNIRYYEYEHDNLFALDEHKSVDPQRGMCFLPRRALNVADCEIARAYKIAGSNIEPIAFIVPRRADGFQSDIFPPAPSSEPSMSANDFFSGKNAPRKVVDLASGASFASSAPPSAVPVPVSASMPSPAPLTPSYSTPAPASQMPSAPAITKSYSIPTPSSTTTAEPPSPAPAPTIQKSNSRDDSTLGQENTQLRKELREARELIRNLELQVEAQRANARKAAQALLDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUQ3</accession>
    <name>A0ABQ8VUQ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_863440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="389" mass="43512" checksum="BDFAEE763F3B1C3B" modified="2025-10-08" version="1">MNQLYPLWPQVQDPPAPPTGAQNAALYLPHRFMNILGMNPPALHFTHFPFSVALNLAPNVPPQALQVPQAGAFPVNLPYNGLLITQRFPLPVTLSNNAVNVNHTQLFSKKFNETAEFLPCTAVQWPAITCTTRQFPGCLPVIPLPSQEQQINAIHGLWAWHQERCTRPTFIEVESEPAVQDEVKKQLLNPLDLLLHKNGTWFNYPRWGRLTIGSNLGQGEHGKHTAGFSDHALYVGGYRQCLAALCEVKTFWAYKSEQMHALSGPSNGTKDVNHKDKVFAQIPGETNVLDWNLRGTATKALKQIWGQMVYNDTHYATWTNGEHILVFLHTGVDELTVTTHNYNGPGGRRSHRWDDPDVLAALFGMCCAAIDSKFLGDQNLMQHFIGPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUR0</accession>
    <name>A0ABQ8VUR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_755074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053216">
        <property type="entry name" value="Appressorial_penetr-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="245" mass="26064" checksum="B60FEF2F32761265" modified="2025-10-08" version="1" fragment="single">QSSLTLDPRVIATGFLNNDVQEAGQVASLTSNNNFINYCLTQGNLPITNGLQTTTGSCNPAPIGTIPSVQNMPSAKFASPANGDTIAANTEFTIQMNINNLDTGNFVNANENYFAAPQQLSAQGQIIGHTHVVIEALSDLAQTTPTNPQQFAFFKGVNTAAVNGAVTADVTSGVPAGAYRLCSINSSSNHQPVIVPIAQHGSLDDCVYVCILCHSASPKHLSEEFFDSTVHCIWRRRNCCECISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV56</accession>
    <name>A0ABQ8VV56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pex19 protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_810787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="384" mass="40940" checksum="2E354AAE8246D143" modified="2025-10-08" version="1">MAGPEIKHKAHLQIEADEDLDDLDDVLSEFTTASPARPTSTAVPVSPLTSPPPPPPTATFAKARPRTNTRVDSAPISIPGTGALQKEVGITERSEDTDDADYIPEGPEDEAALSDAFTKELVKNMQDLMRELADEKTPKSDKGNENKNEETEEGEAERLMKAAWEAMLIEGMNGMTEPPPLPSTSKSTAASTSASGGGPASGAGSDFQSKIKQTMEKLKESEVNLQNSSSSTSTGKPESLQGLLNSLKDLSLDDLGADGDGVEDEAELASFLESMMGQLMSKDVLYEPVKELNEKFPPFLANPPSPLSSADQTRYEKQYDCVKRIAAIFDDPSYKEGGSEGAKIVDLMGQLQTYGNPPESIMGSVPPELMGLGQDGPDGQCIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV81</accession>
    <name>A0ABQ8VV81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="189" mass="20728" checksum="05E23185AF81D46C" modified="2025-10-08" version="1">MLYNTSSFDPFGDGYHPTPSNSTLLSPLDNEFPMLSTFEEPSLSASTSSLWDSNPVRDLEDVAFFNLELVDVVSRRRLGPSSPRRSTPHTMAPEVSPPPPSPCHTEDLKRATVSAHDHFELRSAFSVMSISNFSPSLSAKRVSSPPLNALSLGSPRLNNAIELFQRAASPPSLTPTSPRWNRQNLLSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVF6</accession>
    <name>A0ABQ8VVF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_484258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="17888" checksum="C4DBC5BF0E563CB9" modified="2025-10-08" version="1">MQFGAVIGRQPSYQPRASGSGSDSASSSPTLDSWAPIRSARPSPTIRTPSPPSDSGSSSHSDHRRRFPCLLAGCSRRFTSQYTLKVHMEAHKPKPKVSFLCTLGCSERFSRQHDRLRHEVAKHGKICEFSCDDCGRFFSSGKTLGNHRCPVAQGSTRWVHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVV5</accession>
    <name>A0ABQ8VVV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_892892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF152">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="38528" checksum="1EC3A0F0D14529CD" modified="2025-10-08" version="1">MTSFKGCMLITGANGALGRGFVSCFIRSSYAKDYKGFYVVRSPERAAELKELLEKAPQDHSYEILSLDLSTLASVRAFATSLNARVSSGEIPPIHALVLNAATQQVSGRSFTNDGFEVHFGMNYLDNFLLVLLILHSMDKEHGRIINVASSAHDPHHWGTRDHFPDDVRDSLYTDTEALAKGHLTNESKDNYTVGMRRYGTSKLLGVMWIYELQRRLQSSRTFSNISCINFDPGALPSNLTRDSPLSIRVLIILMRFLNPILLWLNPNGYFRTSSRSGSDLLFATFDEGKLGEMPRALYVDGTQIVLSSKESRDEEKQKRLWRDTLGYANIKDEDTGLENWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW24</accession>
    <name>A0ABQ8VW24_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein PBN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_809990</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PIGX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013233">
        <property type="entry name" value="PIG-X/PBN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040039">
        <property type="entry name" value="PIGX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28650">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28650:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08320">
        <property type="entry name" value="PIG-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00780">
        <property type="entry name" value="PIG-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 10" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="232" mass="25866" checksum="B29FC43537C8C6C1" modified="2025-10-08" version="1">MLLNVSSLIEPLCGFHRTITTSIASENDVWIQLLEESQCLVRLYYKLPVLVFVDPYELVNYQHLYTFHHHGNANLELPVAAMDSNGSSLLLTLTSVNPHVDVKVPIHLRYGEISHSNSEAHRAAEIEWPHLFLSCTSLVQNPNASLISYDLPPEEFASSLAGYSLYVTSEPFRADPDARFMAVAVPVGQIGDLAQVSFGTVLTIVVMFLYVAYISYTTARRLGKRVKLVKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX12</accession>
    <name>A0ABQ8VX12_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="567" mass="63480" checksum="BDF3B842885D0D0E" modified="2025-10-08" version="1">MEDLSTSPETMIPSFQPDIMEITVALKEIQDRISPASTQGQDKQITQFETIQEFHVAVVALSELVSRVERQAHLFTQSAAQWNKQYTPSSSPTGATIGKDSADKASLQIVSPPESPTIRFAQHLTKLPLLPQRGQGLVRVMRHNYRIFVTEFWDGETPLKVRTLLTRMLPTFPLFMDKFTGASKRPVRKAELSVLDGTTVETVKYVPVLPQIIVEILEEYHGHFLETYLDVETLQIILAPAHLFYLINQLAREADVEFGVRVIVTSIVSHLLVLLTEGSKHFFRAGTVHAEEGFEDDGVKRTIPDVEMPPDLLIEVKTWLSFSEDTVHKFLGIPSSQQDAIDASNSVYSVPLFWPTGTETIAVPDQPLLQMATQILNRNITELGMVTSLRFTSFCAIFEKEPRTMYISKVSDIYKREDDSLLQHFAFAAIARDPALRSELFQRLKELPLQGFAKKGSRRSGHLAGNSQSSWKTWGEAAARQQNANRIVYRDVTHEQMGLIGKPIGDDAVGKSLAFHSEQMSSQKNQKGSLPPLDPQRTARNLRTANSTQDSGAQEIGKVRSSTSKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXF9</accession>
    <name>A0ABQ8VXF9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_807738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046930501" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17904" checksum="AE13FD521A49F346" modified="2025-10-08" version="1">MISVQRNIRLLSFFFSRLIMMLSAMTDLSCQTWGLFNNRKHCQMDEWLCPWTCRLWTGSHKVTAMPNRLYCGESSSTAKKMVEFKPRRPSTSLSELIVKSHGTVEKIDNFSDIMMRFGCVKCSLSMRNIICRFGYKRVQWSDEDHGTYGYPMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXZ4</accession>
    <name>A0ABQ8VXZ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127080" evidence="1">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="225" mass="24511" checksum="3A00D82DEBDF57AD" modified="2025-10-08" version="1">MIFPKAILLVLPVLSYLNTIGALPIDPDRLALRAIGTYYRAIEVVEMSANKVGHHPGKPKNKPGDFSNQWGYYMFPSKVDAIFWGNQFKTPNHDSGKGQFAVVELEWSSPVGVTFYEFTSPDDQWKSFVTANYNAGDMADRPKLAGKDYSAVQGPMSYNADPSKSGDYAQETSQVTGKPLTQLAIVALDGLEGVTVKNVDIYNAADWQGGPMPKSVKLAPKSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYC4</accession>
    <name>A0ABQ8VYC4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_203386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="57730" checksum="73667DFA5B432352" modified="2025-10-08" version="1">MSSSEISPLEGVSRVPLDLAERPNIRTCGIGDLPVEVLGHIFSMIHSQTISSSMTNFTTSDTVLRLSHVHPLWRETCISVSSLWSHIHIIRASSDEVKRTEMFLERSGTSLLTIEFRARANTNPYTPEANRMIQKLFAACERWKEASFSVQAQSIEQVMIALFGENKTPRLEQKFHFPFLETLSFTSRPESQNRRFFDIFQHKYTPRLHNLVIPSYTTFLPFAFGQITDLTLSKMNKDFPDLSVLCPHLVRLKIGQTFGESNEPTPAHAATTFELPKLETMIVSCSGPGRLWSTLTLPSLRNLALEAITFMPLEHVAILNMLRRSGCGLGLRRLTLAYMDITDVDVISMLSLMPQLEEFVLHETLIRQQKILTPRLLMVLKLPNTNQDLATTVNDSTFVSPAVTRAHFIPNLAYIELQVYYFPTFGLDLLFDMLSSRAVISSGVHSSPYSTRQASGTLKQIVLRFVLDEVNPPFQIPLELENMVNRLRLVSTSHIQSIVQCGQEWKKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZE5</accession>
    <name>A0ABQ8VZE5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_805695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="12"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="131"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="309"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="342"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="1296"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="483"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="715"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="896"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1069"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1119"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="623"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="400"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="450"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="743"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="760"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="896"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="934"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="955"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1070"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1126"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1172"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1184"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1337" mass="141152" checksum="62AA1A244821C738" modified="2025-10-08" version="1">MSSSSFSPTQAELSLVNQIFNQHDTQKLGILTGDVAVRVFGGAKLQPATLGEIWSISDEENNGWLSKKGVAIALRLIGWAQKGEKVSTDLISKPGPLAVIEGFSIATHHTGMSIPRSPPPISNIPPFTPQDRAKFLNMFMKSNPRDGLLSGEQARDVFVKSRLANDKLLQIWNLADTQDRGALDSTDFAIGMYLIQGVMSGQISVIPTSLPPGLYQQASGGATPSVRSHATGTSISYSPSANQTSFPQNRSYMQPQYTGQMLQPQGTGGAVSKKPLVAPTIPARKTTNPSAIGNSSFGAQARWDVTATEKASSDEYFDTLDTTKAGYIEGEVAVPFMLESKLPGEVLAQVWDLADLNNDGRLTRDGFAVAMHLIQKKLAGGEIPPSLPPSLIPPSMRQQASASIPASPFSPIGQHMQQVPAPEPQKDLFSFDETPPSSAAPSAGLFNIPMQPTGQQSSSVFASPSNFASPSVLASPLSQDPFASSVSKDLLSDDDDHTASAHPLEDQSAEIGNTQNQLNSTNKSLATAKNERISVEQTLANQAAQLSALQVQLSSAKAAYETETKLLETFRERFSKQTADIEKTRTELITAESDLSAMRVEKAEIEGSFLRDKEEVRDLNRRAFEAGHQIETLKAEIEKAKKEAKQQKGLLAIAKKQLSSKEAERVKVEKELAEAQAATVAATQEKEEVDAALEKVTNLIPATAPTVAEPVVAGFPHAERTTSEDSLSFAAAHALPSTPEIGSPSSGKSNNPFERLAKSDPSTPRSQSPFLPFNNATVPSPSVLNGNANQTAEASLDDPFGFAQAFETPDKTPEPVVTEAVAPPPSEDNVGTPKPTIVSLDDHEESPATPTTAHTEEFATPPSTADGILKPMRQSTEDIINSKFPDLDDVATSSAIPSSATVETPTTLNHMPGHFSEPSSAIHETDLGASLNEIEPEDSDSSDDEDEVPLATLKAKTDNLETEPKSAIIPATNGQSATASFDDIFSEPSLNGQAVPTETKDAFGIPIGTESNSPFGSTSASHVASSAEAGVNAFDEAMGKIAPTTFNNTAQFSFENAFDDTFDFGSAKGADASSSFPPAPANGASPAKVKESDGFESLFVMPPSNGVTASVARPVSSFLPNVIASSPPPSTPSSAPDPPVAAGPSFDEVFAGFDSGPTIQLGTLNTAASAPAPIPAPSPIPVPTTKTPGSPTQKPFPATNTSPSQSSVTRSISPPPHRRSPPLRTGSPKPRPSTASSSKEGHEKEKNPPPPRHSKLSIRLPFGKKKKQEAVPPPPPSQFLTPPTEEPEQIGTPAVGDDVEAVKQLTAMGFSRSQAVGALEKYAYDVPRALNSLLGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZH2</accession>
    <name>A0ABQ8VZH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_14520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="269" mass="30668" checksum="7B116EA5A980EACA" modified="2025-10-08" version="1">MAPPHRNSSQLAHPSSPNEPIQTTQTWERLFQRNSLNDCPSSPNDMKLMLRIRDTVCAFPYINDIPHSLDDMRKFKFTIAKGSDIYGHLKMAMPYRDWSSEGIFYFPGCVHQFTTNAQHFLAFGPHPQQIPSSDLQKSRYASSSFAATNHVIRSRFQHLYGTICELFVNRPNGYFCYAGTYKMYALDYLMPNGIDRPDYVSLFSIAHAATPPSQPRVFPNIIELEALYKTGVLKVECAALQLVGFDESIYRAVKRVQTAKVPQKPAKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2Q0</accession>
    <name>A0ABQ8W2Q0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_892254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF5">
        <property type="entry name" value="FAMILY ACETYLTRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="25790" checksum="102253DB0C71B017" modified="2025-10-08" version="1">MLIQQGMDKNFCFPIPDALENSRPSKHAEALVQAFDENTWNYLSYGPFTSTEQFVEQFWEKGMRVNPATTSFTILDKTSPVNGEPAIAGLVSYINSSDQDACTEIGFVVILPKFQRTHVTSNMVGLLMHYALDLPEKGGLGLRRLQWVCNTKNAPSLKVAERMGFRFEGVLRWARVLPPSKAIGYKAAPERKGDPRSGKGGRDSAYSSCCWDDWEGGVRDWVDKVMTRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AKH4</accession>
    <name>A0A9W9AKH4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nucleic acid-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_559001</name>
        <name evidence="5" type="ORF">C8R41DRAFT_788587</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000011">
        <property type="protein sequence ID" value="KAJ4484839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AKH4"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4484839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13577" checksum="F6C17D2A6D9345B3" modified="2023-11-08" version="1">MPPMAFRGLVTKVGFMNKTATVTVTRMVAHKTTRKRIERTKKYLTHDPENQLQKDDIVIIRNCPPVSARKRFKLETVISSPETERAKMRARRAIEQAKTTSTTNVLPTDALRALLSEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DHT5</accession>
    <name>A0A9W9DHT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme/RWD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8J55DRAFT_521435</name>
        <name evidence="4" type="ORF">C8R41DRAFT_815274</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000029">
        <property type="protein sequence ID" value="KAJ4471347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DHT5"/>
    <dbReference type="OrthoDB" id="406833at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23808">
        <property type="entry name" value="UBCc_UBE2W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000072">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="153" mass="17401" checksum="337C7BEA3634A6A3" modified="2023-11-08" version="1">MTSISSRRLAKELMEIKNEGCPVGINLVQADDFSTWLFTIEVMGESLYQNEKFTLQFRFDQQYPISSPAVQFVVTEGRQAPVHPHVYSNGHICASILGNEWSPVLSVIAVCVTLQSMLASCKEKHRPVDNDRYVKHAPENPKKTRFHYDDDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9E004</accession>
    <name>A0A9W9E004_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Osmotin thaumatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_160597</name>
        <name evidence="3" type="ORF">C8R41DRAFT_130545</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000144">
        <property type="protein sequence ID" value="KAJ4464263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000003">
        <property type="protein sequence ID" value="KAJ4493475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9E004"/>
    <dbReference type="SMR" id="A0A9W9E004"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.110.10:FF:000004">
        <property type="entry name" value="THAUMATIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040981356" evidence="2">
        <location>
            <begin position="19"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="28"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="96"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="150"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="155"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="256" mass="26332" checksum="9121406CBEFA5D6C" modified="2023-11-08" version="1">MIGIISVVSFLLASGASADRTFTVTNNCDYTVWPGMFTNLQVGTAVPDQANGWEQAAGATVSFTVPDNWTSGRIWGRTECDFTTVQGPTSCATGGCNGGLVCDASTGTGVPPATVAEWTLSGAQDLDYYDVSVVDGFNVPVAVTVSDTSCSTASCPADLNSDCPADLQVLDSSGAVVGCNSACNANLDGDQADSANCCTGSHDTAATCPPSGVTDYDFFKDACPDSYVYAYDESSGTALWTCPDSASPDYTLTFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9E172</accession>
    <name>A0A9W9E172_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 11">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8J55DRAFT_553688</name>
        <name evidence="13" type="ORF">C8R41DRAFT_418470</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 11"/>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000001">
        <property type="protein sequence ID" value="KAJ4495936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9E172"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07849">
        <property type="entry name" value="STKc_ERK1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000040">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000028">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="14"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4486805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4495936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="367" mass="41671" checksum="133C229F17FC6601" modified="2023-11-08" version="1">MDDRTTAFIVGSSYQPLDIIGEGAYGVVCSAVHIQSQRKVAIKRITPFDHSMFCLRTLREIKLLRHFQHENIIGILDILKPNLGPDGSLDGMTEVYLVQELMETDLHRVIRTQELSDDHCQYFIYQTLRALKALHSADVLHRDLKPSNLLLNANCDLKLCDFGLARSARPPPDHPVDASTFMTEYVATRWYRAPEVMLTFKQYTKAIDIWSLGCVLAEMLSGKPLFPGRDYHHQLSLILDVLGTPTLDDFYAISSSRSREYIRALPFRKKKVFGKPVHEGGVKGFEGKNPLAIDLMEKCLSFNPKRRIDVEGALAHPYLAPYHDPSDEPGAERIDSEFWSFDTFNNGKGLSKEELKVLIYEEVMRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXZ2</accession>
    <name>A0ABQ8UXZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4939 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_781832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000127">
        <property type="protein sequence ID" value="KAJ4465437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032549">
        <property type="entry name" value="DUF4939"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16297">
        <property type="entry name" value="DUF4939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4939" evidence="2">
        <location>
            <begin position="7"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="38340" checksum="868759048B03015E" modified="2025-10-08" version="1">METLGTVLAALGRPSDSSESKSKVKEPEVFNGLDPRKLKTFFINLALVFNDRPKYFTDQRKVNYTLSYLSGSAKEWFVPDILDPDLDSLPAWTSSFKALVKELQDNFGIYDAQDEAKDSLDARRYAKARTKDDIENVRDIITEAFPARVHRDWFRAEKNAHLALVLESLAERIKDKMTRLPGLATLADYRLEVLRIDNRYWKREAGKPFIAWNPKKGSSDFKTGSSNQHNNSQPSGSSAPSMPKPKPFSGGKPNNNGKPQNSSNSGQSGGQRPAFNHLGADGKVLPSERERRMKNNLCLFCGGKHQIADCNKRKARELKGHAAEVEETPQATIEVVEEESEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZU5</accession>
    <name>A0ABQ8UZU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_52496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6533" evidence="1">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="118" mass="13505" checksum="618EA85B764771B4" modified="2025-10-08" version="1">MLSPDLLKAIIASLEGSEIARIVNIACLALSVYEWSITLDQEIEYFWTGKWTISRILFFLNRYIPPFLVMLGLIEFSIPNPSNELHLGYPVLIRLINPRLGYHPSDAHSPYMVPFPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0C0</accession>
    <name>A0ABQ8V0C0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="286" mass="31742" checksum="516F91EEC6B770DF" modified="2025-10-08" version="1">MGFEITHRQGGELEKKGGQNEIARAKRNTNWQLVVHVSGEARCLRHEITGGKRATTMRSGLGIVSSHVAWDYCAFIAISRDTRREAMLLHASSRSRFFDSLVSQPMESGRKISIQDQLYTCASFIIVLLYVLFGNVINGLYHRVPTYPRERALSTVVVSGHIRLHPSTVSVGCLDTSVHPYALILVLGVDRWGITNLFYYCFLGGGVADTLLSAISSGTSDGRKIDIRLIQTNQRLHMVDVEGTLWTDEIDSRLFRTSQTTPDSLSKYPGILIATPRTSGPDSEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V172</accession>
    <name>A0ABQ8V172_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="728" mass="79596" checksum="AE1F450EBDA6191D" modified="2025-10-08" version="1">MASSSSQTRTGASSTLLPTSLAEAQELIAGLKSKSSQPLFFESDLFQHLLEGDYSPPILDSQNLPDHDSSKPFPAFSYPSALVPFCFPPGSSRHLSVASGLDLFCSASMITQILHPSIEASDSLDSGEAFNAFEEAAPFLAYIHDFWIGHANCPLFAEHVLRTADGLYQCLPAFLRDSLEQQWGIPFNHQSSFLGPSDFKQFPVIPILRLASPKDLDPFVSLRSSMTETRLLPGGPRVPSPVEDSFESSEENQSVAPPKRNKRKRELVSLMADASTILDRRSNVKSPSKDDRPVLPKASSSKKKMEKPVPKPKATARSKTTVKVVEESRVSPESEELATPSYQIKRVRLPPRLRQAAKGKARQMEVLDVEESVTEEEVVPPPSKRLKSSKSAPAPPKASNFRPALLIDEQGRLKLPGDSVEGFTPFKRIEHARNSAPLQCQNPIFDVNPEFLDLGVVLTTQKASFTMQDLLQINRSIRDPSIPAQACVSALSRGEFNPNASRLPGLKCESCSSRSLKCMCSLDVDLAMDALNALHVATTSSTISLTNSLRRTQELRLQLDRLGALFDQARQSFLRSFLDLQQAGQDPIVVLEALKAAEPQRKSLSIEDWTLLATLFQWSSPFNLNGLKFDNWTPAEWIDLLRSIHSGASSATVTADGHLVDTSQLPEAAVEVSEALDPQGSPPITVIEKVSGVENLASLSEGSSIQTELDLPQIESLTESTPSPEKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V209</accession>
    <name>A0ABQ8V209_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="692" mass="77325" checksum="28F7537225C49931" modified="2025-10-08" version="1">MESHLELQTEIEHLYATLEEMQSSSEAFNTNTIALVKATQQSLSQMVVHTHNLVAYVNGFKMDFSLKLESNLRQTQLHSSNPRKDISQNRDRIHLILTHLQARSDQTASAPNSVTQAIAAIHSKEPVIPPNASRMTEDTLQILHFLWLCQEVTKVKAVRLYCSTQYGCHQLPVNTPVFESIALELFIPSDTGISDTRQPYQLMTLFRKFKNQRVAEVSDIIIECQQQRRKIAEDTRERNLLLQRREVHHKNAYSQIDAQAVTMIESLNRKLGEVEERIHLNAESTASLAVKQLWSQTQNFSDLWSTLLRHLLANSDHMQNASTRIQLAKETLEALQPQPRGVFKNHEPCLEEGTNTGTPVRHPHGCTKECDINSIPVIFSKEVGQQVADNGNSKSHHGLNSGYPDEVTASNDISNWELVSRESPNVLCLMEELRIQDWRNVVHCGETPVNTLSLEHLGECLEVISGLFQISQISDTSEDNHAQENCTTPLVIPEIVQVCSDNENLTTSVSKGALQDGGIESSEACDLVSEVGVSQSALVFENSGPQINEEVSPCEPEHSSKEIEDENLDQELPDVSCGLDAAVIYDMDSGKTPLEAFGRLNEQRHKLHNMLNARTINTHPKRGRGLYIDMWSGGRAGFSQFLRETKADALLLGAVRRPLALDQIRRDASQQQWTEQLDAGFSTGAMGAVGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V283</accession>
    <name>A0ABQ8V283_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_777614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="564"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="596"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1177"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1691"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1750"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="634"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1177"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1694"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1756"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1771"/>
            <end position="1780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4470050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1801" mass="202839" checksum="F17AD13972DA2DA2" modified="2025-10-08" version="1">MHQNSEAQAFIDRVLALPKGPGVSLESVLQPSLDDEAALRRLFATEKDNNRLKNPYVGLVNVFDAPPDIRTIRARIVKDEEDLNGKYVMPLSPKDRKAEGTACMVPSLEEFQKNWAVFSEGSLSQLLDWNNVVAAGGSVLACLVPLPEEAKVSKRAIRKYYHGSAYPSSDIDLFLWGLTPQQAEAKIVKIYEAVRDSVPWDVTCVRTKHTVSIHSQYPYRSVQIVLRLYTSPAEILAGFDIDAPCCAYDGRRIWANPRAITALMRQCNTIDVTRRSPSYEVRLTKYSSRAFEIYVPNLCRADIDPTIYERSIVRVEGLARLLVFEKLKYPNAREIFLQSRRTLRGRSYANSVPYYIRKKRSLKGDLKNEVAIGGLEMNSYDVVSLHIPYGPGWDARKIDKLIYQTDLGMNSTFNPKNKNRRLHRHPAFFGTIEECLEDCCEDCPKPIDEDEVKLQEEEDKQYLRGRISFVQQDPGRQSLSGSFNPIDDSEWSAQVFIGPTEKFFQVIITSDRAAIARMIAEGVDVNRRDHVGRMPLHVAVLAKAEDVACDLIDAGARITSRLAEGKTALHIAAQLDQLKVVKKLLERSKINEDLLKKDGDAEEEGNGDVEMKEAVRDSSEDDWSSADDGVISMEEVEDTDVDDEDDGDDVDDDNGDDNDGSPRKKTKSKEVSEPPKTPSEYNALPEDDSGEPDVFDINAPDWDLCFTPLSYAILFASLPVIDTLLLSGADANLATTASYPDAPRLHPLLLTVYHSDEEQACFIAERLLQAGAASSAADQGRTILYKMIEAGKTKLVNSLLRLDPKAGVVLNLPSMDMNNGRPTFPLIAAVQLNNYEMATTLLAYGANIVFKAEDVVRAQELRNHHFINFTLGEPLDQVIHPVEAALCCHTDLIQLLVSVGASINRATRVSMSTYANQEILRTYLDWARYAIGWINRYISEQQDKMELETKKLDSITTALSTPWRTFVSRTIYLSDNGVLPGSELQKKKFVEDQVELEKTTRKCVALKGFFGDAERLLVSKGAKTYNILFADTEKRSTATSNVSIQIDHRDHIFWQQNSNSTKYFFLGQHDYSREAVPMYLNDRYDELFEVCWKGDDTTVRKLCLPDEGKENALRVSVAVAHPTNQWSQTNLTPLVAAIEGRHWSTVRLVFAICVAQYKPVDEKEVAFRLKDINLDEDDEDNLSDDDSEASDVTASAQKRNQPFIDIAQISSAVKVPFPPSRLLDSHYVTYEEGGGSLVLIKAIKTKDLEAFVHIADLYKLTEPPLELGQGYILDAILEADEPEMLDEYIRRTGSGIDLQSHGDETEEKEIRAINDKNKIYLGLLVHGKKRKDLAQKNDPVNFHYQLRDQDVTPILWRAILSSSKEVKIIEYLASTRPLEAYQFYAMTHGSELSIRLRRITDLEQILPDRLGWRINNLGESPLVAAILSNKLNVIKLLFAKNPKLMSAALKERIKFSGFNLLMIAVQVGCDPQVIDFLLANGQSPTETDQVRKWNIYHMLAASSVPVLFEHLLLKLPRDVNELLLQQHCKGNLDTPLHLAVSRGDYRTSSIIIDYTRAGLAIRNVYGSIPLHIAISKSQAKTVKKLIDSSPDECLFMENGVGNTPLEMSTLLDLLGRLQNVSRDREPELSAQHVNLDPSRITLDKLQQDVPNLRQTINTLLKNGPLKVDDKLTKELFAFSRFMETKLTAATAEAEATKRGNEDEPDVKDKWKDPEDRGTTLKIIKEAILARPHQRQLIHLVDVQKSVDSHLSSAELRSTDAHNQRHQREHDEEGLEPEEDTEIKLRNSSIVYRRLGQPLLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2G3</accession>
    <name>A0ABQ8V2G3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_612802</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="8"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="303"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4470741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="458" mass="50108" checksum="EB6E96FE3853BC21" modified="2025-10-08" version="1">MTNTLPTETQIIVVGAGPTGLAAAISLIYSGIDPSNLTIVDCVEKGANTSRALTIHAATLEALDKYDCASRLIELGIKGTGWRLGDKTSTIFQATFDHIASYTKFPFVLILEQSTTERVLEGRLKELGVEVKRPWRVTGMRDSKEFQGTDILFESGETVRTRYVIGADGARSSVRQLSGINFADPDGKSVDDSVDPRVAQMVLADVSISLPEDQAALQASGISLTASEAGMFLLVPLGKPTVSEQLYSSSETVYRIGFNVPRGLGEPPSKPSLEYLQNNTNLHAPSVLSSDPDVNPNPVRITKVHWSTRFRMRSALAEVFFKRVHGGIVFLLGDAAHIHSPAGGQMSMNLGLRDAAGLGPVLADHIRRRESKLSAPGARNWDVSDMDFDTTTLEDYAASRRIRGLENIRLTKDFTNILNFVSRPHLLSRLLLWIFKLLLSLAIFQSRLVYRLSGLGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2K0</accession>
    <name>A0ABQ8V2K0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_970048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="114"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4470768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="351" mass="37912" checksum="B905B59B872E2457" modified="2025-10-08" version="1">MPAVRGTSVIRTDVEAPFICSQCGTRTFRKADLQRHEKIHTGIRHQCPHEGCKFSASQRSNLNTHLALHDPSRRRACPDCAFCCKDPSSLIRHRKSKHSYVPKKYTVAEQPLKFLPPEVPSPNDPTSTPSVDLPHTNSSKAGNASEVADHPHPSILYQTPTRLAPSPGTKDVVGIAAAPAASLHLPSKDYGQTPLSALPFPFAEYPCAADFPPNLSRATLFGPWQGFYSEYSHLPHPSSQYSKSFSGTDTGNDIAAGSGSRIASQIHFGVGLEMGVQTANNFSVGMAMDTNRRLTPAPPLVPSLSMGSTYGHSSYGAHPDPARRSNIWEVGQDYNETPGAGSSTYASLQYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Z1</accession>
    <name>A0ABQ8V2Z1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_45059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the free Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000614">
        <property type="entry name" value="FRMsr_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF15">
        <property type="entry name" value="FREE METHIONINE-R-SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01320">
        <property type="entry name" value="UPF0067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="88"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="186" mass="20581" checksum="CEE7C84C19BA1DFC" modified="2025-10-08" version="1">MNRVKTKTQFWTHVHSQLESLLDGQRNWVSNLANTSSLIYNALLAFPTHFGPDSDKAVNWCGFYIDSTRFPKSTDWEVEGNRLLLGPFCGKPACQFINVTPGKARGVCADAFMDAETKSVPDVDSYPGHIACDGETKSEIVCPLIHGNQVLGVLDLDCLAMCGFDEDDQKGLEKIVELVVNACDWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3J6</accession>
    <name>A0ABQ8V3J6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_851361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="62" mass="7369" checksum="31F0040D22D413AC" modified="2025-10-08" version="1">MLQHKLILPKPTLRPILTQVLQNSSQTVISMGLNFLFKCLNPLFWLDFFHVVLYTHWVINFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4K9</accession>
    <name>A0ABQ8V4K9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_775143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF3">
        <property type="entry name" value="BNR_ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="Sialidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045828921" evidence="1">
        <location>
            <begin position="17"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="380" mass="41132" checksum="D5D00C57D4584709" modified="2025-10-08" version="1">MLLPAIFLASFVIAHPTPEFIAHRAPKVLEEVTIFIPPSTYTIPRTLYARTLLLETDGNETDVLLATWENYSPEPPYFPIFQSTDSGSTWTEISQVTDQVNGWGLRYQPFLYELPSEFGGFPAGAILCAGNSIPADLSATQIDLYASTDKGLTWTFVSHIASGGVAEPVNGDTPVWEPFLMLYQDEMIVYYSDQRDPDFGQKLVHQTSTDLLTWEAAVNDVAYDVFDDRPGMTTVALLPNGSYIMTYEFFGAPEASFAVYYRISDDPTAFDSVPGQVLRATDGTIPTSSPYITWSSVGGANGILAVSANSDSAVYLNQCLGAPNAWTRVSTPESASYSRNVRVLPGGILLITGAGVLSGTDNSVTTSSIDLNTVTLASCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4M3</accession>
    <name>A0ABQ8V4M3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_849610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045089120" evidence="1">
        <location>
            <begin position="30"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="200" mass="22047" checksum="5BCBFE9836358C40" modified="2025-10-08" version="1">MHLRHFVSFTIPLTVLLFRTVHLIPGAHAVPIDSEAIVSREPSWNTPDNGGDGDVVPVPEVVVSTTNVDLHARFIHNPPLHRLRQDIIKIFCTNAKPSIALPPAANSLTTLQEDITKFVTAAKSAMGLKGLGDPKVEFTNPEKCVFVSMEAPLEYTVQVEGHTKCAERETSFCRGTMYRRAGKETIKAENNTLLYPPPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Q7</accession>
    <name>A0ABQ8V4Q7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_854100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF19">
        <property type="entry name" value="NUCLEUS-VACUOLE JUNCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="270"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="489"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="568"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="933"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1013"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1051"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="629"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="737"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="774"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="786"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="824"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="862"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="943"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="955"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1026"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1059"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1084"/>
            <end position="1121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4468546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1168" mass="126420" checksum="94B100E67EB511CF" modified="2025-10-08" version="1">MSLKIIFYVYILGGFTLVPLLLCALVAYAIYTSEPVSEDSKAKSIVTEEDVGKDVPDVQDMPKTRKGWLTVRRTFEQSTFDGGYVTLVRSFLDARSKDPKRSRPKDMWYVVLKGQILYLYEDETMTDCEAAIQLGSHDVVIYPEGLLDGELFTKRNSICLKPKLDVKVMPSLTREMKLNENDDGERTKEGEKARKVAESAAQAMAREQALDQQSPWFIFVRSTVEMEDWYFALVHASQHPAQTPTLDALQTVFSPSDMNLLVSTLDEQPDIIPMRWFNAIFGRIFYSFYKTQHLETFIIGRLMKKLSKVKRPNFLNDILVTEVSVGNRTPVFSKPMLKELTREGDASMEVHVAFKGEVRITLQATATINLGARFKPYVVKLVLAAVLRELEGNLLIKVKRPPSNRIWYAFTQMPKMVLNVEPIVSDRQITWNMILSTIESSLKTIIQESIVMPNMDDIAFFDTSRRGGMTRGGIWADAAQKHSGFVIPNEAQPTASDAGPPQDPFLSNDEITSTDSLPPSVHKSSSLQETSSSAAEPPSLVPSYTMPEDASSNRRKTWFSSVRNTHTDAEYSSDNNMESESRGRTLDVDTRKTPAVRSQSTPNAESILENDEEGATTPSSLAVPLVKQRSASQSSSGTVNELSNELSTSSASDNTRIGQNNDGSSLAVPAPTPDTPPSPNNFLTTLKSRAADKQALSNTAKETMRKWGMKWGGMNKPSPGSSSSSSHEDIPDHDTVGESSGLTHSRSRTMSALGGASSNSQKTRASYAEVRAAVAERKGRVEHSQELSPSRSLTPSATSTPIAIPPNTNLSSQNTEFSDNGLVSSSGSSVSSSSIRDSSSYPNKPILDSNGGASDMHNQIMSVSSSASNSSSTTSTKSSTISVDEAKLSSRSHVNPDVSIDEVAPVHAPIHVQPQAKTMSIPGIHASHRGEVMSLGYVPPSPQEDKTKDKQRGRTTSQGSSTLSNLSSLGASSMGSLSKNPKLQSMYRLWKQAASNNSNSEIHGVHNGLAEDAAGSSPALSLETDLASTSNGTLSQPEPSAIQAAPVLPASMTSLSKRVPPPPLPPRPSPVTISPSRPPPLPARTPSSAGLASLTNSSSIPQQSPNPSSQSLMPPQPTMSSAQDVLKGIATKDDHTRKRASLTLSSTPPSPTIGRRVSLTGPRSPRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V560</accession>
    <name>A0ABQ8V560_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_847802</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="172" mass="19552" checksum="D5A62F6B8D980AD9" modified="2025-10-08" version="1">MTRSQIRFNHRVAKKLKMTCMEAGMSRSDAAKLSLSCLPVPKVSGTTRRNPGRMDGVQWKSDSFLCPERVDGFESFYGDSGAISLLDIARPAKSKGDYLQLSSVREYGQMLKIIHCCILGIAKEYEVVKGVRQVIFLDDEEVCLKEQWEEWEEIHEPSDTEKPTYADVLKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V670</accession>
    <name>A0ABQ8V670_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_779529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="224" mass="24485" checksum="D9204A1C40FA4239" modified="2025-10-08" version="1" fragment="single">AELKQKAVKAKDATVSTVQNTKDRHTSVPLKKTNWNPYDGKPPPPPAPRTNNSWTKPPKPEPPKLPPPPIRRDTSNSSSPSSSPRPPTISPSPSQLSSSSSPALPSRSPSSGPPVVNRATRPSDPAVSTPSPNLRPIPSPNRTPSTASNINRLPALPSRAPSLQAPSLPSRTPSSSSYRHTSESEYQTQIDWTHFSQQDKEVFFSWLDEFFERSYGIRPPVSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V680</accession>
    <name>A0ABQ8V680_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_846321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="117" mass="13470" checksum="2E21CE5BEAB1FB8E" modified="2025-10-08" version="1">MSAPMTYFSNRQSANAIFPNAHNFTVCNSTFNAYEGDINYILPNDEEKKLQEWLSAPNSSINYTTALNKRTPGTGVWIFDHPIYNAWREEHGILWIQGKGFLVSSWIRKDSSTFHHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6L6</accession>
    <name>A0ABQ8V6L6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_527396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="333" mass="37126" checksum="74AC326445B1D1F5" modified="2025-10-08" version="1">MTMLLYIKHRLVIDKIRNDYLSFVRQLKPDGPAVDWLSLLRTHHPDLCDGTSFEYAICVRKDISSKWCPHNSLVSLALNSYVHPLTILVRLCMLLDETGAKVQYTLGTTENWTTSQLSKRDILEKFKYNKDDENLILENMQLAADIYALMPKPFKRFKKGDGGGKTDGTLPNQESRGEPLQGDDSVGGDSGQEDGEGGGRDGQGDDNVWVQDPNLNRGCSRIPSSINVEDSLLRSSSLEGSNSIDDQGINELLFEIFKERDVAPKVNKWVSGLEPRLPSSSTTIREHAQSLGKERESEVGILTLTKRKTRSFLLSLRVLLSQSRTGGDSNLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V735</accession>
    <name>A0ABQ8V735_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exosome complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_844502</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="137"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4477926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="40362" checksum="73655D59E0F96DE6" modified="2025-10-08" version="1">MASAETRKAKSRLKVLSSSLTEIEAAIAPLLSGERTLPEILLALEPLEQAKLQTALPYLVYDLIFIYLRTRGIDPKTHPVVTELERVRQYFEKIKNAENTPVRGTQVDKAAANRFIMHAISQAQIDADAAGVAYAPTKASSSSSSTTPLTTSASNSAGANPSDPSTSSAARVPLKVTSKMLERQEWQKRVDEAGSEEEEDDIEGWEEGDRVQEDEDSEVKTNSISKGKGKGKAVELLDDAEKLGSKRRRPVIDPFEASGFNDSDNPSNSHPTKKQALLPRTRISSTTTANPSSTSSSSTSTTVDGPNTPATKAEVKKTRRKDKKKKNKQKQKAAMKDLELKAPGRAGRVVELLAEVAASQGAVVVSSSESGEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V779</accession>
    <name>A0ABQ8V779_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arginase/deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_844656</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF26">
        <property type="entry name" value="GUANIDINO ACID HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047088143" evidence="5">
        <location>
            <begin position="42"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4477971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="416" mass="45722" checksum="03CCA341771F9505" modified="2025-10-08" version="1">MEPMTQLTLSLFEFALTGPTMSHSTSLLILGVLLFSVTSIAHDHSPEQNAFKLEKCQESLKESTWLDKYGPQIDQSFSGPLSFSHLPYTRCLENEETKFDIAILGMPFDTAVTYRPGARFGPYAIRSGSRRQREARGYTLSWAKDPFAQGVKIIDCGDVPVNPFDNALAIDQMEVAYSTLLRRALATPERAKGAMPNPHPRIISLGGDHTIVLPILRALNKVHGPISVIHFDAHLDTWRSYPGAVTNQSRVTHGTFFAVAQEEGLISDTSIHAGIRCKLEGEEDLENDESVGFQLISGDDIDDLGIPEIIRLIRKRIGDSPVYLSLDIDVIDPGLAPATGTPEAGGWTTRELKRILRGLAGLNLVGADIVEVAPAYDNAEITGIAAADLVHDFLMMFLSDHPPTKRKAREDPRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7B8</accession>
    <name>A0ABQ8V7B8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047323532" evidence="2">
        <location>
            <begin position="26"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4477564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="403" mass="43987" checksum="81DC009E21148F75" modified="2025-10-08" version="1">MHIPHNRMINLSLAYILIAIIFVSAVPISSPQSILTSHHQRHNNFIQSRVDDSHHPETPAVASSSSSGGTVESIPGLTGTTSTTSPMDSTTLFIVQYPNDAPPPEVRNPNFQPSINKGTQGLVLGAAQKLKVDMKFEGDVKNTFKFHGFASKPSPGGYGFKVHLLKKAGGGSGSRDEWVECSGTLKTRLNPESKLVYYGEVVDLTGKPIFSLDSGAAVSLGMTVTMKKPEIVVKFEKEIRSPDVPISYQKNANRGSLSLVKEAIKVLGLGIEALDSNTQFSGYVSKKRSKEDRFKFELFDKRGNDGQGVWIPCTGILRMVVNETKELIFYGKVIDLKGEPIVTLNNKGKVVPKKRPGPSNDDKPGVRDEEKNEEQKRKGAGKQVKWADPESVDIPDNQGSRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7R5</accession>
    <name>A0ABQ8V7R5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_888242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="362"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="362"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4473472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="413" mass="45724" checksum="8884275D0F85749F" modified="2025-10-08" version="1">MTTQSMSTVNQQMWDEALKSILSLSKATIKHNMELEVRVADLEMELLVWKRAHSVALEASERDNVHIASLHKQITNPDGSRENGNPLVLCVINGQKIFFNQALLMQGFMGGQNAAQYLTKAISDYLASETVQIFGRVSFWVSIYFNKIELVSTLVGQDVCSREQLEGFLAGFSEASPRFTAVDVGIGEGAADRKIREYIQTYTRLPETYKIFLGGCYESDAHYSSAFDNLQSENLLGKLVLLHSLLDDCSDQTFAVPALNVEKILVQQPLHPSRQQLTPLSVAASMEPVAGPSHGGLVSPQSPGCIGMRYPDPRYPLHKQSPPPCNEHYLMACSKGFFKAGACKYSHDYMLTPEQLAMLAANAKKAPCNWLKSGLRCPYGDSCCWGHVCPNGSRCFHLSKGKCWFKGEGMHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V844</accession>
    <name>A0ABQ8V844_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_843571</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046184593" description="Mitochondrial carrier" evidence="9">
        <location>
            <begin position="29"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4479478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32838" checksum="555F242E4AC6057A" modified="2025-10-08" version="1">MVIPRHFVPPMLVNALLGTVLWTTYTEASKVMEPHISQHPTMTAALCGAIAGGFQAIVAAPAENVRILFEGGSMYHSWSHAWKDVFRGTEVRGPTSRQEKFEDARQVRRWMKEVGDMAGRGWNGWIWGCAKDTTGFAVFFSIFEVTRRTAFRTREDTALYIRETFSNDEFVVHHIPKMIHSFTLVSGGVLAGLAYEFTGRPWDHARRTVHLQKLQNPTEYAPWWAIFQQLRQEGLSGFFENPALTHAPNPDPSIGSGYRPKLAVALRTLGRVGPWGIGFLIYESFGPGLQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8L6</accession>
    <name>A0ABQ8V8L6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_842693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="64" mass="7511" checksum="693231B0AB0C1DBF" modified="2025-10-08" version="1">MNPQPNPIFHDPPRCLRRRGMAALYKWRKLRLRHIGPSILSLSDTNIGYWRILAGLSRSFSFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V975</accession>
    <name>A0ABQ8V975_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_470466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="223"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4481782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="395" mass="44255" checksum="0E323848159583E3" modified="2025-10-08" version="1">MITVQRFTRLPTLQLESPFMFLNLNRYSSKSLARTRTRSALSITSVHEIILFFAMADSTAPVFHVELVFGPMLIGVYFNMILFGVLLNQMHFYFQNYKADALWIKCLVAYLFVVETANTVFDMVIMYQPLITEYGTEKAVANFPTLFMTEPIVVVLVSMPIQCFFAWRISKITKSYIIPGFIVVLALTSATGGFITGIKVAILKLFIKKPELHWSALLWFLPSCVADIIITITLVRSLSKRKTGFGATNTMIDKLIRMTVQTGMITAICAIGDVACFMALPHTAINFTWDLALAKLYTNCLMSTLNARSALVNRSQTSTSGMFINVVDSASQKDIRRQLESGTSDAYELESAKTVEAVHDQDSSYHENHTELQITVNKFVERIEDSIESGNASAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9A1</accession>
    <name>A0ABQ8V9A1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_959867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="69" mass="8222" checksum="81124A63ACF98786" modified="2025-10-08" version="1">MDDTPLRTRGEDCWKWIWNGTRLITSRDLQSHPVTGWFITHGGWNSIQEERSSIEFRCKIFWPCQADQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9D9</accession>
    <name>A0ABQ8V9D9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_534992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045564">
        <property type="entry name" value="DUF5910"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19287">
        <property type="entry name" value="DUF5910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045475329" evidence="1">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="25295" checksum="33DE5E989DB664AB" modified="2025-10-08" version="1">MIPSLNVLVPLLLLIRFSLVVACPVPVIDERGLTFDKIVGFHYTDETAAKEYNQAGTLTSDVGGYKHIHPVPMDSDHQRHWKCEIRILQLENLLEAPKLFITDRSANVWSGLQRLENYIKDAKLNVRNTIMFGEPLSAAFLGKEPKQVIMFLPSDYLEKSKRNPLALHGSNSLGLRAKCVPPREYLRVREIAEWRDWRILRWPDALHTQLVDSDDSHSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9W7</accession>
    <name>A0ABQ8V9W7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_724307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="247" mass="28634" checksum="B58C1AFA5F0C2FDE" modified="2025-10-08" version="1" fragment="single">KIDETVLPWLNRASSSNRASLSESLEKTRVILANLAREPKYARSTIQSQPDCPVFSTEDWDDIVNGKPARFDHIFSSMHATTLDERQTQKVGEVEFKFGPPVPGKRVNNSGDWQIVFAKYSKALAFVFPHRADELERYSEHIVRLFGALPELDHDKVINYDKAIRYRVSQSRQYELTDFSEFQDLFLHWIQAPPSRVKESGQRENKSRRREPCKRYNEGRCPNTAQSCGYQHVCGKCNRNDHTRPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA00</accession>
    <name>A0ABQ8VA00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_841711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053221">
        <property type="entry name" value="Burnettramic_acid_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887">
        <property type="entry name" value="CHROMOSOME 21, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="499" mass="53755" checksum="F60614D858CE57CB" modified="2025-10-08" version="1">MDSSSSTRMSMPTPSTVEDTPTGTSSGVHLAHDADLLIRTYISSSLSLAQPPTGLPIPLPLCIPQVSVNPNDQSAFARGYSDTLKDVGIPQDVLLNFIDGLNMAIIASPPLRVVGMVGTIIGMVPYHWAMIAGTVISTAAGVATHVLSKTLTDRYLRAANLTLFKPRGFSVRLCTTTAMLALLTSSESKTRSKLNKLGRGVGSVLLKLPIPVINPIASTIIHAIADKPPTIAPSGREGDPINSPVLRRRVAMTNGLALPLKMDGLPPPAKPEGVMDTMASWGVKYDTARERLSEKNIERRRRALESIKQAGIEPPSRSMGLLGTGLPMSSRPGLRPPSTSTGRSDSSSASSSSGFRGMASSAFNTVNDLRLQMEVRNERIEQQRNASLFNSGRGNGGLGGLLGPKMTRMEQKVADADLLEHWGAEKFLWIVVMASDKDEEIADIAIADDPANEEHIDDETWRERMAFERDEMELEDIQELEQLEQHESSAGTQASGSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAB1</accession>
    <name>A0ABQ8VAB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_840335</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="14">
        <location>
            <begin position="65"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="326"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="452"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4484058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="465" mass="53098" checksum="4B25045747B5A972" modified="2025-10-08" version="1">MKLDATDLRYVTGDEFRVLTAVEMGSKNHEVVPTSLITQISGLRNGGVNKIIGSLAKRNLVARVQNSRYDGYRLTYGGYDFLAMRALSKRDSMYSVGNQIGVGKESDIHIVADNEGKEMVLKLHRLGRISFRTIKQNRDYLGKRKSASWMYMSRLAAQKEWAFMKVLHEHGFPVPTPVDQARHCILMEFIDAYPLRQIADIPSPGKLYSSLMDIIVRFARAGLIHGDFNEFNILIRRETGEPVVIDFPQMVSTSHENAEWYFNRDVECIKTFFRRRFKYESALYPKFRRTLANEERGEDFQLDVVVAASGFSRKDMKILEEYMDEVKEADTGSSDEVESEESEDDMQDVLRLSPKEEIDDSASVHSPPPFQNRSISPTASDEEPPESDHESTRNLSRSPPRSRSISPAADHSARNVKDIVKSNLDKSRARQQRKYHSKRSTQRAGRAQGSKAKQDTRVKLDSTWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB14</accession>
    <name>A0ABQ8VB14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_843714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="67"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4478865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="429" mass="48197" checksum="2117102BF29EE3DD" modified="2025-10-08" version="1">MSSRHQPIGIMIDPIPGLQNQEFYVDKDGTSRVDLSFVEEPLGLPGSKGYGWPQLEFGERIGPDLRYEIKRKLGWGMSSSTWLAYDTGMNDYVAIKALTGFSTELRRRGRVWELEALQRVAGSNHCLHLLNEFTHPGKGSSGDHSCLVTPVYGGDVKILWTRHKEIKNFPLPLAKRMLLHTLRGIAHAHSKGVIHTDLKHDNIFFTSLLSRQDIDANVVSDPPRRNPPEASLDGAVCSAVTQPLPVPSLDDAMKCQYLIADFGSAQLFDKPKELEVTSAPLRAPEVLLLGSWNEKVDIWTFGCLIFEFIVGRSLFRHEAFTNTALNVTLDDIAYHLYQMACFIGEVEFPPEVLQYSRLASTYFNTDCTFKNSLPLQWFSIKGQINNTQNFSPEDVKSTTEIVERCLELDPADRPTAAELLNDPWFVGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBJ8</accession>
    <name>A0ABQ8VBJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_838408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="477" mass="51398" checksum="9A80F2371E9CB1A8" modified="2025-10-08" version="1">MGSSFSSATKPKIFYPPSPEEILVKKPGGGVGPESLSKLVEEHCPSLKKEFNPPWWLNNGHLQTLFSVAGDFTSVDKVVYERTYLRLMDGGTLGLDFTPPGDTSPDDAPIVVVCHGLTGGSYEAYVRAVLAPACAPVSEGGLGYRAVVVNFRGCAGVPVTSKQLYSAGWTEDLRMATIYLAHKYPKAPQLGLGFSLGANVMVRYLAEEGERSRLESACVLGNPWDLVKNNWALEHTFLGKHIYSKGMANNLVNVLKLHSKALEKVDPPTPSATSKYEPDSTQASLVCAAYHAALALRSPPLSVFDNTFTRVGGGGPPDWPLASADAYYKHSSSHHVVPQVRKPLLAINSTDDPVVVHAPTSPEEVGSGYTVVVLTEGGGHLGWFEPSSGIVLIGTDVSKLHVRRWMTKPTLEWLRLAAEVLVHGHPDHPPRAIFVDEGGWIREVNGARQGLGCRAVEIGDLIDGTELKKEPGMLQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBN0</accession>
    <name>A0ABQ8VBN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_771613</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.830">
        <property type="entry name" value="Ile-tRNA synthetase CP2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050081">
        <property type="entry name" value="Ile-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="56"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="767"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="633"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4479846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1030" mass="115562" checksum="4DCD545C845969DD" modified="2025-10-08" version="1">MLRNAGARFSRAFSTVPLDTKAFSDTLFLPKTAFPLRPDPTKNEILYRSRTCEELYRWQRKNIDGPEFVFHDGPPYANGDLHMGHALNKILKDIINRFALLKGRKVHYIPGWDCHGLPIENKALKELGKDSSNVPPSTIRAAAHAVAVREIASQKEQFRQFGIMADWDDNASTYRTLDHSYEMRQLRVFEQMVNNGLIHRRYRPVHYSPSSRSALAEAELVYKENHVSHSVYVTFALDHPSAELVLKTTNLSSFEPIQLLVWTTTPWTLTANMGIAVHSDMVYTLLRRMTDSSLTLIAQSRLEALQDILGPIEILAELKGSVDLIGLQYSPIFSSLCDTEPPAMRILGSSHVTSESGTGLVHCAPAHGEEDYKLFRSYDLISSGTQSPSTAMSNTLVCHVHDGLFSEKVVDVVGPSAHMLVGQPVLEEGSRGVVELLKQAGRLLAVKRYTHKYPYDWKTDKPIIVTATSQWFANLDRIKDDALKALNDVQFYPNQSRNRLESFIQSRSEWCISRQRVWGVPIPALLNTRTGDAMLNRESLRHIINVLEEKGVKHWWEGPVEEFLPPEMKTLDAGEWQKSTDTMDVWFDSGTSWSMLDPPAPSEGRSFRADVCLEGSDQHRGWFQSQLLTAVGSASETTAEHPSGDATPNAKLRSPYGTLITHGMVLDEKGKKMSKSLGNIVSPLTIVLGGTDKKNDPAYGADILRLWAASVEFKTDISIGRTSLTQTAEAMRKIRNSARFMLGNIRDGTALEGLERVQRKDMGLVERFIMHELYVLEKIALKGYEEFDFAKVTAALVNFANTTLSSLYFDITKDCLYANSFRSIERKAVVTVLEKILDTTTSILAPILPHLAEEIHQHLARDQNLHLKSKSFFEKGWKPLDPEWEDYAAAKDMSYLSKIRKAVLGLLEEARGHKRVKSSLEAEVDILLPNEGGDHPVVELLKREEQILKTLFITSDACLVDEGSLGSSSQSSVWVYTESLDLGEDLGMHYALGIRVRPASVAKCPRCWTYTKHSKEETTCARCADVLRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC86</accession>
    <name>A0ABQ8VC86_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_472894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="474" mass="51066" checksum="FEC11D5CCE50F8E9" modified="2025-10-08" version="1">MTKLIKPHPPHTPSRTNAHTNESKESEEVQEPKDSKAVAFPTTSDASPFSTPSKFKFYRSSRHSTSSTSSSDNQDDHDGLRLRKPSLLKTVKRVSTKQLRSISSTLTNSAHRITLHGHGHGHHIDHSSESSESSQLSEPPHSTQSFDSSHLAPSPHSSQSAEHPELAEAKSDSSSKDARRRRVSLPSFRLLRPSSYSRSRTGSNVGSVPSSTVTSLPVPPVPANLDIGVGRSHSSPSISTERNIESTVLSPVLASPSVTPITAAATPTPTSPTPMAVSVPAALSADGEGRDTKDFRATSLGTGDDSFHHADAQEARPHPPGLLVSVELVPTSPITITSNEKAKAQTQTPSMTSRGVTEDDTAASLPPLPSSSRSVVSVSSFFSYTLPPSASPNHYSWTDDIDEQKGSENESDDEDEDSDDDSEEHIKTEKDLNRVGSHRVSEGPFISSVFILVPVFSVRRPIGFYLTWWLGRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDF3</accession>
    <name>A0ABQ8VDF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_903390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="152" mass="16368" checksum="51B35A35FE8876F0" modified="2025-10-08" version="1">MYFYVPSQNTRSRRLGMGSAGTDGAKEFGSTGQALKSRRVPIANASKAAVGTVGSILVAHKGQTTGVVSTLGNNPTLKQQQAHSYSKSQNVGLLLYMAKDKFVDHNNEVHDTELNIEEQKAELNYWNTAHGSIGAKNLSSDVESEVSDKSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDP9</accession>
    <name>A0ABQ8VDP9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_982911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4479856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="465" mass="54184" checksum="0A9CF953A35A0C1B" modified="2025-10-08" version="1">MNSHANAGYAMVEAPAPKAHQNKTSSQILEMLVSYNQRFSRLHWSQFDQFVFYKNPSTLSFFDDFTGRPSQTYCGESGGWVYHVIGDYVEMIRPPSIRNGKELMTHKLKYRFEVLAFAVDYISRNVAALEKEDGKCVIHLRNPQGRKNSRTFSWPMDWSLIVRPLQFQIVGPYIALNFEPVRTARRAQLFTVANWTTGEIVFTREFVETFQFIAADSFLYATFITDCFPDDNPSVLKVFQVIVYEGQIRQHERLRDVMVNKQRHLLRSVNFIPRAGPPMKALKPWNPDGLDHFVHNIFDPVPYEDRNGPFHSDPNEQIIGFHFVAVDTHPFFIVFDQKHFLGSCRCLTPRRGIGHFPTINGKRLLWWNEHTLEIYLRDYKPNCAQLYGGGTIRVRHPQDQGWKMSSWIQEDPPVNVNDSFGDNTFVATASENNASTRRHVYFTEDSIFMIEYWRDGTMEGRIYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE96</accession>
    <name>A0ABQ8VE96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA prenyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_766523</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13965">
        <property type="entry name" value="PT_UbiA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4491098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="294" mass="33922" checksum="5561730B90D19492" modified="2025-10-08" version="1">MFPKLDISQQIIYHAMTGYLFCKSDIMTTVLPVTILAFTATPLCTDHPISHAIQSMFWLLLHLLQFNLSNQLYSINEDRENHPYRPLASGRITISMAFNLRWLSTWICLFVSLFYGKAVLEASFFSALFALLYNETKFHKHWFYRCSFNALGYGAFKLGTMLISSCDNSVLDSVALDALLIGMAMIWTTVYVQDFQDIEGDTMMERATLPIVFPTLSRAAVMPMLLLWSIFLWNFWNLAFYAGTSIVLLAVAVSARFWLARNIKADKISYLWYNLWLAICFMLPAYYRVRSSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VER3</accession>
    <name>A0ABQ8VER3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carnitine acetyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_839227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="4">
        <location>
            <begin position="52"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="643" mass="71780" checksum="1CA802DD1EF80EFD" modified="2025-10-08" version="1">MFPARLSKYLSKKPLNTIMHISHQRNTHWKTFAPSALPGSETFAAQSSLPKLPVPELSGTLSYLKESLKPIAWNEAEYRAVVSKIDEFGAGIGPELQKRLLKRQAETDHWLERWWDDGAYLGYRESVVVNVSYYYGFDDHPSHLRQTPAARAAALARGAMLFRKKLKQGQITPEGTREGPFCMDTYRWMFDCCRIPGSDGLDWSKSLAVEGDTGDSGHIIVMRRNRIWRIDAAVNGRILSTDELESQIKYIYENTTQSYPGVGILTASNRDVWAKDYAELVTSEHNSDILDTIHSSAFIICLEEGAPSSPEQNSRVLWHGHFSNGQAVGLQNRWVDKPCQFIVYDNMYAGFMGEHSIMDGTPTVRLCDEVLDALASPSFDHGVKLSGQPAILPPTPLDWKISAATAQAIMTANAAALDLINSQVLSYYLTPYGKDEIKKFGVSPDSWAQMIIQLAYRRTIGNENRKGGTYEAATTRKFYKGRTEAIRVVTSESDAWVKSMDNPNASNATRKELFDLATKKHVALAKLCGAGQGIDRHILGLKKLLAESEETPALFSDPVFTRSSYWVLSTSAIFSKHFNAYGWGEVVPDGFGVAYMTGHNDRLQYTITSRKEMPNSKFINEIASAARDLYNLHKTVGTSKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF56</accession>
    <name>A0ABQ8VF56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="51381" checksum="8E8E567FDAFACA8E" modified="2025-10-08" version="1">MHEILNQYINNMAGFLPADCGGSEVDFQGIVRFPGLAFGFDRLNEQMKEKIKTVAHGYLLTSKIDTVFGEDETEYIEYGLARILSKQGRKSIRIDEPLVLLSCSIWFNHQPAHTLYKTATDNIQDHNPSTGRNGFEEFIALYLLNVFQTPTQLKDVFDFSGVAGKLNDQGLENKLATLVTLHLDDNAGSSELVEGKICLFGDPRLSGPIGLGIVSNGNPVLNDWLNLKRHTAFCFPMNAMGPDILCFLKLEDMANSDFTYFHRAEKDLAPLTLRKAVATITPEEFFERRKTSDTTTNRMSTLASLKALPHRDPHAGKYGVIRIVCGFPVKVDLSKPSFSTEELANGQGRRVKAEDPSGNDNHPVAKLKIETLIETTRHEHPKNILHVIEQKAIEARDAGHGAYDENDPAILLPGVHEVREVMPIGMDDLIFTERIFMNSVQDDYGQKRFSTGLKWGYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFA9</accession>
    <name>A0ABQ8VFA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="266" mass="30172" checksum="7F232DA4C9D483FF" modified="2025-10-08" version="1">MQSLNPEFGRGKAHELDPTVDQLGSENTFRERPVAPHADQFRSGYNLNQAEIDSFYMIEAERLVDGFQSQMQKLIKDEISLPSWKPTFNSPDLKIPQDHKEFIHNLKIPLARAPHHNLPDMLLYELGRFQQDKRLEARIQALFTAEPYHKIFVNTSGAGKTRLVLEHLCSSWGLYFSCHDSSHVGSKDLPSAMSNIRQSLDQSILPHAPNLLVTSADIAAHARDKGIPHRDITEADVLTNRIANFKKDVPKSDQFRQALQKKPTSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGM4</accession>
    <name>A0ABQ8VGM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CinA C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_764463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="entry name" value="CinA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="CinA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA C-terminal" evidence="1">
        <location>
            <begin position="11"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="18572" checksum="92B68B6674CB1D25" modified="2025-10-08" version="1">MSFLTPTLKLLASEISSVLILRNETLSIAETACGGLMGAAILTVPGTSKCFKGSMAAYSLESRVAFLGWTREILDGYKGPDEQIVIGLASHLRKTLSSTWCLSESGVCGPSRPDVYRAEIEGPGYCAFAVVGDGNRTVSKEVRIPQPKSREENMVAMAEEGLKLLLDTLKAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGR6</accession>
    <name>A0ABQ8VGR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_713506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="1">
        <location>
            <begin position="101"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="18661" checksum="B9254D81F5819966" modified="2025-10-08" version="1" fragment="single">FPPPPLSDSQLATVIKNWCDASSADHFEESGCSVCGQLTLKKDLSPLSHVKNCLHILEAEGVTREPRQESTDPIQELKGPVLDLSAGDNICNSCRASLRSGKVPRLALCNGLWLGNVPNVLQGLTFYEKMLISRVRYTKNFVRVQKGGGIHSKMVSNVIAFENPIPLIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGV5</accession>
    <name>A0ABQ8VGV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_764028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF4">
        <property type="entry name" value="S-ADENOSYL-METHIONINE-STEROL-C-METHYLTRANSFERAS (AFU_ORTHOLOGUE AFUA_4G09190)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="177"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4494173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="403" mass="44673" checksum="5AC581C2B09FC5CC" modified="2025-10-08" version="1">MSTRSSPVAIQTAVPVPTPSKASATAPSRGSSDRTDSSDSIAETKQKTVKVKGTSSVDVDRSASTGRLKTMRNSYRVLKNLTPKQMDDFMNSYVIYGLDWENEAQMITTLGPDYPTAVHDCLVSYYSVLNHLCALGEVEKMYIPPLMNAHAGILDNQLLYEEFVAREIELKSGDHVLDLGCGRGRVAAHMSKYTGAHVTGLNLDADQLASARTFAAKRKLPLEFIQQDFNVLPLKLETESFDAFYQIQALSLCKDLPATFREIYRVLKPGAKLSLLDWVSLPAYDSGNSEHAELMRRIKPLIGAVGTPTAEKFHTALEEAGFHVLKSDNASIDGLQAPLIERADGYFRRLQSLVLALVKLRVLPPHFKTLMLRLTQDGQAFIQADRMRLITTSYHILAEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH42</accession>
    <name>A0ABQ8VH42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_919232</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SGF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="118"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4494260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="35583" checksum="C13F19D606CC00F7" modified="2025-10-08" version="1">MAPSKAERAEREQILSTLSNRLFCDFLDDFIMDVALEAHAEVSRSRALCENCGTRCNGAHVPASLTSRALVSSSRAETPSAAEGGANTPNSAKGSDGTVHLECVNCQRMVASNRYAPHLSNCMGLNSSRRGAVRGSTKAKQPSDAGRSGSPASEAGYPSDDGKLAQKGKGKSKTKRADEAEFNLKRKRPLSPQVSPSKKQKQKVQSGSPVSRAKSDMDSASLLPTTNSQSKIPSKLRDSSLASFNDRETSGSSRESSPDASLSSTLSSNFMNKGMANRPKPIPLKQPSPPRPPPPVPAYIEGLRFSIRSVAIVDSNLLPDDEGDETGSSTDTSDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHB1</accession>
    <name>A0ABQ8VHB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Septin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_763622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="4">
        <location>
            <begin position="14"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="370" mass="42601" checksum="8C08072216E54EE6" modified="2025-10-08" version="1">MSFAGRRRGNKVKKGVQFTVMVVGASGTGRTTFVNTLCESEVLAHKISDSPDTAHVEEGIRIKPFNVELEEDGVRIALTIVDTPGFGDNIDNEFAFQEIVGYLERQYDDILAEESRIKRNPRFRDNRVHALLYFIPPTGHSLREMDIELMRRLSPRANVIPVVGKADSLTPSELRGFKKRIMEDIEHYDIPVYNFPYDVEEDDEETIQDNSELRALLPFAIIGSEEEIEIDGQPVRARIYPWGIAEVDNPKHSDFSRLRSALLNSHLGDLKSLTHDVLYETYRTEKLSRTVHADNNDSSILPEELASQSVRLKEEQLRREEEKVYYQRKIELKVQREINEKRQELLAKEESLRNLESRLAAQGSQSEFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHM2</accession>
    <name>A0ABQ8VHM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127068" description="Heme haloperoxidase family profile domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27323" checksum="192BCAFCADA2DEB7" modified="2025-10-08" version="1">MFLLLVLISVLIAAQTVQTAFIPILRSSSSSFSGNSSEITLSQLDAIINGTSCPLKGSQFLDECRTAAQALPFVNKGFADYNITTVGEKAALLSLMSFESGGFQFNINHFPGNPGQGTHNLMEFPSVYQYALILSQQTLALIPNINHNKLKSNISLSSLSSNLPDETKNIIRAVVLGDGLSFASAMWFYTQSGATQLGQPGQGCLKLPGMVQGLQAQTQAGWENYITNCVGTTVTDERRKSYLTTLQILNGNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHN6</accession>
    <name>A0ABQ8VHN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_765747</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF119">
        <property type="entry name" value="ROA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="583"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1004"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1029"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1078"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1112"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1152"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1230"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="23"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="660"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4491759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1271" mass="139837" checksum="CA2C7AC9446B72FA" modified="2025-10-08" version="1">MRQVSVDVTTSRSLTKIFSKARSSCSDVEADNPKAKRILDGTSADFPKGSLCAIMGGSGSGKTTLLNILSRRMQNASMVLSGSVLYNGSPELSTVTSAYVTQMDLLLPSLTVQETLLYAAALRLPSRTTAVERRNLVEEIILELGLKECAHTQVGDGASHRGCSGGERRRLSIGVQMLSNPSVLFCDEPTTGLDATSAYQLIKMLKSLASKGRTIICTIHQPRHDIFFLFDRITLLSQGFTVYSGPTDESVNWFESLIPGSLSEHLNPADYLIGVAAVDDRTPEAESKTRAQLHRLVEVWKKESSNRFLLPSSADSVKVKGPPRPVHTAGIWRQIQVLTSRTIVTTIRDPMGLTASWMEAVVMGLVCGLVFLNLPKTLAGIRSREAALYIACGLQGYLVLLYDIYRLTGPSLALFDREHSERVVGVVPWVISTRIARLLLEDVIVPFLFSVIYYFMCGFDPDASQFFRFYAVVLLNQYIAVSFAMLCAAISRDFAIATLIANLMFTFQSFSCGFFIQAATIPVYVRWIKWVGYCFYGFAALVANEFSGKFYDCPESGGPSNPACIQYTGDFILENLSFHPNWYTVPVCALLGFVVVFNLSATLLLLFWTVDVQVAGTHIAKNTDTNGPERYQDVSGMKKEKERDKSVDIDVDLIDLALTIEKTSLRKGFTKVHIPILHAVTTRFEAGSVNVIMGPSGSGKSSLLNLMALRFKSTPLTRYNSSGNLLLNGFQPDESELRSLCSYVTQDDNSLLPYLTVREMLRFAAGLRLPGSITMKEKNNRAEEVIRMMGLSNCADCLIGSEFVKGISGGEKRRVSIAVQVLTEPRILIADEPTSGLDAFTASSILDVLNGLAAEGRTVIITIHQSRSELFPQFGNLLLLAKGGRVAYSGKASLMMPYFGRLGYQCPSNCNPSDWALDLVSVDLRDEKAEAASRLKVEEILDAYEPNPPTGIESNLSDESKHRKYRPLPPNLVSLKKEPAPFYVAFPILIRRGLINFQRQPSLGIARIGQVLGLGLVQALFFAPLKRDYIAASVNIVGAVQEILPLYFVGMLQNVALYPIERDVFYKEHDDGAYSVEAFFAAYVCLEVPFEIISALLYSLLGDIAINLKRTIPMYFIIALNCFCIVSCGESLGIIFNTLFQSTGFALNVTSVLLSVGTFMGGLMSIDMIGFLQGINYISPLKYATANMLPYTLQGMTFTCGDTQRLANGQCPLNTGEQVLDLYKLNVDPAPMLGALVGATAVYRLVAYIILRISRTDFSHLAQSRYTVKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHP2</accession>
    <name>A0ABQ8VHP2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_832688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="51" mass="6287" checksum="2B64114AE9D397D0" modified="2025-10-08" version="1">MHISEFRQLPRTRVILAHDEPWYNWYKKNIGLFHGRVYVLQDRSHLRRVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHP8</accession>
    <name>A0ABQ8VHP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_306736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14725">
        <property type="entry name" value="ZIP_Gal4-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="581" mass="64884" checksum="3945336A4C95F88E" modified="2025-10-08" version="1">MANKATFTDKGTLQRGKACLRCRKRKMRCDGNRPACQQCTHAKKPDGCEYDDGKGKTRTQLLRETIQQLQQRVRELEDPEYISPAVMLHDPHPPMSESSSSSYDSAGSTPISISHSPYPSESKSSPSETWTHLPVSSPSPSPFMSDIFFEDPRSYQSSFDLGPILLDIFSPHRHQCGLGIHMGHLRESLNLSPDEQRHPALMNSIYLWACFVSRPKPLSQHEESFLSQALDGVRDGLRKGDKLLDVIQASCLLSLYFLANGRLVEGSFHASAVAALAVQCGLQTAVSGEGSYNPSSSRERLDLDHIRPGYQEGERVLTFWQVYNLDCCWSVALRKPRVALDSEDPWTSIDCPWPQDITDYESGNATVSNGFPTVKTFLQGDVSGGFSMQTWRAKASAIFSRADQLAASWRYRLSGVTYPEEFQVLELTINRFLPTILPIHQLNATILEEKHTLIVVHTLIQVSVLMLYQRFAQDDPVTYDKCSAAAKACVAITKFVSEQDYDYLDPIIGSCWTTVAEWLICEITNIESAWALSMTSTDVRNDISTILYAMTTLNARFPVLGISISKIQKRMAELSLNSNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHZ5</accession>
    <name>A0ABQ8VHZ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_866593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="2">
        <location>
            <begin position="3"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="277" mass="31225" checksum="8C5E377849EA6D77" modified="2025-10-08" version="1">MLSLSSPSRVLAQVTVKLYHAKFSGMEYDWQYFNQRGTIQFCLNNCEADVELSTTEESASSKLIEADYWFRLRDELSGKILWTFSIPEECRYHIEKPFFHIFNGRSRMWGFLFDRDEDGYAFGQSVQAHLPSSATQDSQMKVRKSPSKHSGRAPSVRSERTTISRFENFGFSNASAATLAPQVSPEHKPRPPMMGLSTSIISLPQTNSFLHIGHIGLGRDGVIECSEGINPAWSKVITELQTHASLVPEALKRKEFFNNLRSGIKRLGPATVRSGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI18</accession>
    <name>A0ABQ8VI18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Dihydropteroate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_828533</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the DHNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="16">
        <location>
            <begin position="526"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4495285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="849" mass="93942" checksum="E5A4AC4B91ADF77E" modified="2025-10-08" version="1">MRDSDLIRVNDLLVTVLLHSGSRWPSKGSTPTAQPVHISLAIPHDISSAARSDDLSQSINYSTLASTLRTCLSPTVASHEEPAFESMEQILFRCFDVLLLHETTSAPRLPGAKIKIVQLKPPLHCKVLAIEGEAAFGPSASWRLTKIDHIVEDLGCNPIIGVNPAERLERQLVRINITVETLNATRALKNWLDFRALTRRLYQKVEETSYLTLEALASFVAVETLQHLQSHLDNIADYNPKIRVKAAKPCALVFADSSEVEITRYFEDYPMELTLASEASSRPDSSPSAIHCAAIALGSNVGDSIQNIELALRLLENPLLVVGDRSTISQNAFVYIVNTSFLYESAPMYVTDQPSFINCACMIETNIPPVDLLQLVKKIEEIVGRKPSFRNGPRAIDLDIVLYDELNFDTRAQEEQHTLDNLNGHLVIPHPRMSEREFVLRPLYDMIPEYVHPSLHKSISTLLNELTLISDDPHMDKVIAFPQYPLPPNNTSPLPGVDPVPSILTHWKYRDSRSIRTVPARTQGKTRLMATLNVTPDSFSDGSTHNTLPTALAYVHEAVRVSVDILDIGGYSTRPGASFVSVEEEIDRVVPFIQAMRSANLATTEDDSEENRMVRDMPISIDTFRWEVAENAIPAGANCINDVYAFTGPQNYPYPASGAAKQQMTEYMRKMKDVARKFAVPVVLMHSRGDAGMNKDYSVYDYSDDGSVLEGVRVELGMKVDEIVKGRGCIRRWNVIVDPGIGFSKTVEGNLELLRQGAAVTADRLIGSGSNEKKRNPLAGFPQLVGTSKKSFLGMILSDKRGKSTEAKDRIWATAGAVACAVQQGALVVRVHDTHEMSDVVAIADALWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI43</accession>
    <name>A0ABQ8VI43_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_724942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="160" mass="18293" checksum="70E45248CDFE6A40" modified="2025-10-08" version="1" fragment="single">GMKVHGRLYKVHRYFLERDSLFLRGALSTVQGTQSQPIELHGVSNQEFESLLDFFYDGMYRSSADAVPVSEWINLLAAASALKFNRAREHAIAAISDVSQRPTAIDMIVMAEKYGITKWLRPAYISFCKRTEPLQLNEAERIGLDKVVKLIQAREEFLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIN2</accession>
    <name>A0ABQ8VIN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_834997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046930486" evidence="2">
        <location>
            <begin position="22"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="24599" checksum="D160C59B93BD683E" modified="2025-10-08" version="1">MLLISIHTVVMVFGLFNLLCAMPVSVNNAVGSHSDDESQLSPRRAKPVDSQAYHGSKANLVPSEPALPPGGAPTPPRTGSPTRPPTEQSASHPATPSTGKVWITFTDATTSAHNSNPAFQQEVTDIVKRGLARTAAFSPERHGERIFDFRNSFPSNSLAQRQVIHCKVEDEWLRGQCGSGCLGSVAFVDDSGPRSFHGRVRVLDEDEQEPYERYPRVSLPPPPPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL21</accession>
    <name>A0ABQ8VL21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heme peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_828989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1089" mass="120046" checksum="2071418B6D07B404" modified="2025-10-08" version="1">MAQITPLQVFELGADDVYLKSRSPPTAPDGRYDWQVPANANQSPHAHSGITNLMQEMQTIKAKASPPDIKMADALIDQVINPNAVDDRKGGISDALTVLAALPASSEAAVKIGNAAIGLLYNTVPHPVAALMGEVHSFRHADGGGNNLQTPDIGRAGMPYARSVQSKWCSSSFSLPDPNIVFETLLKRRDIVAHPGGNSSLTFAFASLVTHSLFRTDYKNMNINDTSSYLDLSPLYGINQAAQDLVRDKAAGRGLLYPDTFSEERLLFLPPAASVLLVILSRNHNYIAETLLKINERGRWTDPPPSDETARALQDEEIFQTARLVNGGHFMSLIMGDYVPGFLGLSEGNSWNMNAFDPITNLNGTEVTRGQGNHVSVEFNVLYRWHATTSAADEQWTNDFFKSTFTKPLDELTPTDFGGAFFKILAQLDPDPSKRTFSGLIRGPDGRFSDDALADILHSATENAAGAYRARGTPAALKVIEVLGIQQARQWGVCTMNEFRQYLGLKTFSTFEEWNPDPEIANAARRLYIHIDNLELYTGLQCEATMPLSEGLRFACGYTMTRAILGDAIALVRGDRFYTTDFTPANLTTWGYQDTMRDPNNGGLGGNLPKLLTRHLPRHYPFNSVYACYPFFTPQKMQDSLTRQKIAQNYTFTRPVAAPIPKVLNTFTGIKYAFNDPSKFHTAYQMSGLGNGYGFMLAFDADVKKHDADKALALHALFPSQDSLDSYRRWYRENAIQRIKEKSWTYDGVPGRYVDIVNDVINATSVRWAADRLCGIDVKTKDNPSGVYTEQEVYDMFALLFTITFLSFGDNEHLFSLTVAAFQAGGVVQALVAKAILEVAPSSAPNALVSVASRVRGYFWPSTAKPYYPFLSTLSGTGRPVNELVANVVSLAIGSSVNYAQAAVNVIDFYFDDERAPERAKIIELAKASDDKSTELLRGYVREAMRLNPQYTGLYRDAVVDTVIPQGPGLEPLAVKAGDRIWASFKNAHRNPAEFPDPLKVDPTRPQSAYNLNGTGYHQCPGVTYAEQTIAETVKVVFSLKNIRRADGNAGRLGGFTVIKDETETNVYLKPNGILTSWPGSMYLVYDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLM4</accession>
    <name>A0ABQ8VLM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_979749</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF33">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="37510" checksum="DD6CDFBB65FFC274" modified="2025-10-08" version="1">MSAPSIPSDVAPTGFVPILDDQLFEHGERLKDKVVIITGAANGIGKEAAIRFASFGAKILIGDLDVVGAEKTVSDIVASGGQATARKCNVTMWDDQVELFDLAIQKYGSVDVVIPNAGIGEPESFLEVKLDKTGRPQKINLPTVHVNLTGVLYSVHLAQHYLVVNRKLDTQPLKAIVLIGSMASWQAFPLAPTYSASKHAVLGLMRSLDPILTLRGIRIACINPFFADTGILPTPLKVFLAGCPLTPVPRIAGAIIYAASHPDPATSGCAYVLPDDGPVFKVPREEFKAGVYQLLDGKLQTTTGIVYAIKYATDIVKIVAKPLSALVIAVGLARVLWFNRRTLWTFMDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLP1</accession>
    <name>A0ABQ8VLP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_895133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="211"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4496482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="33093" checksum="7EFDDCF4EC4DDE27" modified="2025-10-08" version="1">MLRRLGTVFKELGGAVRSGIVEFSSTEITQDCENNFCFGATPVPGKMGMTMAGLGFFSHTQNDPGNQLHIGNVYLKDLFHTAGNIICANIDIRANGCPKGSGTAVFETPKDAQQTISMYHGFEWYGCILEVREDHFAGLTGAACGGFYGGLCGGLCGGFRDGMRGGFGGGPSHHFSNRPNQHVLGSRMDNYGGGFGASMGYRGYTEPEPSQQIMICNLPWSTTNEDLVKLFETMGQVELAEFLLEGTCSKNCSIVQFMQMTEGETAIAKFQQYMYGGQPLDIWFNDHWHTFTMAAAKGGVNLLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM66</accession>
    <name>A0ABQ8VM66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_219750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047051579" evidence="2">
        <location>
            <begin position="21"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="31654" checksum="FB3A9C072F391085" modified="2025-10-08" version="1">MHLNQLFVYLLLGIVSGAAGAPISSNVIASSEFTTGITQSSNVESSSNPDIRTIGALSHPTQSVVPVDSHTVMEARSGNISENWEEVQHPGQAPGHPVDSEKGDEDWETVHHPGQAPGHPTKSTAAAHPGPPRTGAKVPKQKPKGPEDNSLVSFLSYTWVGIETSHLGDIGNNDDELIRHEAVALVEKAAKFKWKLTNYYINRNNPYMYPAAARSDTMNTTEFKFLLKLEYDVLKGKDYCGGRVRGESEDGCIGIVRWGEDKSGKGRISELINKDGVVVKMRSGYDDIDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMK5</accession>
    <name>A0ABQ8VMK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol-3-phosphate O-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_894553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="695" mass="77263" checksum="9ECB552A5252555E" modified="2025-10-08" version="1">MGDPKNSHIGYDVSMFFWKLIVNIFFREIRPRGAFNIPSDGPVIFVGAPHANQMLDPLLLSIHVYKETGRHVQFLAAAKSLQRTFVGAFSRLMESIPVVRAADNAKAGIGTIYLSETDSCLVLGIDTKFTQEFAPRMQIQLGKVVKYAFAEVIEVVSDTELRIRQEFRVANDSGNDTVTTLLRNKAAESRSAGNGGALEFKTVPYVNQQEMYRYVYDRLRHGGSLGIFPEGGSHDRADLLPLKASVSVMALGAMANDPACRIKIVPVGLSYFHPHKFRSRAVVEFGSVMDVPMELVEMYKQGGSQKREAVSKFLDLIYDALKTVTVRAPDYDTLMLVQAVRRLYKTPTQHLTLGQVVQLNRRLLNGYPHFKDEPRIQKLRTDVLKYNRSLRDLGIRDHQVPRVQKATWKILGLLLYRVGLLIFWTVFAMPGTILNGPVFILASVISKRKAKADLAASTVKITGRDVLATWKGLIALGVAPLLYPFYALLVALLSIRVDASFKWRMLAPLSVFVALPLTSFSALKFGEAGMDVLKSLGPLITVLIPGQQRSFDKLRSTREKLSRSYGGDTGISASFMRTMPSASTPPSAGTSSLWRRKTNVGAVDAQGLGLVHPMTWLDERLFGWSGYTTGGLQEDEVRPDDEDDDEGDYEAVVSRYDELVKGNDGGLRTNLLYTKLRQRRLGSDIAITHAGIREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMU0</accession>
    <name>A0ABQ8VMU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_820765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="254"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="35751" checksum="9112012C39405821" modified="2025-10-08" version="1">MLASFDRTSLLTHPFFIVTTLFANASWMIALISQGLAATKYGRSTVATLWLAILLQFLVNIGVLYGLYTNLIHMFRLQLSLFASMAVVLGALGINNNIFSGFRSRDAIAAAWIILSIVDLLWILVFSSERDSPVLQVFEKEARIRLSSDSNFPIDREEESQTHSPIPKDPISESKLALDPRTTRFSAPETFKSDDAARPALLQPSPIVYEGSRTSFDRPGSVLMNDRQSTTSRLTVPASIATHESSNAASSNYSYSQKALALYNYNAINSSTEVDNSGEGELSFVKGDILEVSRTLEKKWWPARRSNGQVGVVPSNYLQVIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNB4</accession>
    <name>A0ABQ8VNB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_894313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042453">
        <property type="entry name" value="WDR53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44666">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44666:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="356" mass="38703" checksum="04116C6A9F66B7C2" modified="2025-10-08" version="1">MNGSCPYVVVKTLNTPAPVSSFDFGHAGHLFAGSDDGTLRVYDLSSFKVLKAVRGLKNEVSSIACFKRSGSEFRDAWVACGNQIFLFKMDMSSMIATAEDAILSLRLTEDDDVLNEIALDPTKKHLAFSTDSGVVGVVDLTSLLVAKMKEQHTSVCACVKFVPDRPREIVSAGYDETFLHFDFREGTILSQQKISFSQSTEGVSLSPPFILSTAFSSTGILAAGTADGSLWIGLGGQKVLSKSKLKRYRKWNGLSDGEKQIFIKVVDGPIVAMSFSSPDILTTSTLLGSIAQWRINCETSDQDKNIKELWRKKGIALEKVNALVTNDTKIVIGGFSKHGKGIIEIWDRGAPIEASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNK3</accession>
    <name>A0ABQ8VNK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_820415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004864">
        <property type="entry name" value="LEA_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03168">
        <property type="entry name" value="LEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Late embryogenesis abundant protein LEA-2 subgroup" evidence="3">
        <location>
            <begin position="162"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="32650" checksum="14DB24FA6319E125" modified="2025-10-08" version="1">MAYNDQYAGHQEYNPYSNSQPHASYEEPHAAAYDNYGPGYQDTSYPATGFNKTRDADELSSGFDRGEFGSPRGEKAQNIRQYRREFRNDNLWTKGGRGSCIGRFFCCTLMIAVFMIVSIVLALALWIRPPSIIIGSAGLTSAGTNGIQLETSGITVPLEVNISVNNPNYFSVDLKKVTLDLTYPLDGNDTAIGNGSTSDITFHSHSNTSFTFPFEIDYQFSTDPNYAILLDMASKCGILGGSQSDLTIDYSIKVDLKIIFISVSPTITNSFSIACPFDESELEDFIKSLGLSSILGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNQ5</accession>
    <name>A0ABQ8VNQ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Inositol-pentakisphosphate 2-kinase</fullName>
            <ecNumber evidence="2 8">2.7.1.158</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_177223</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20313"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.158"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="8">The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.158" evidence="2 8"/>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.110">
        <property type="entry name" value="Inositol-pentakisphosphate 2-kinase, N-lobe"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009286">
        <property type="entry name" value="Ins_P5_2-kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043001">
        <property type="entry name" value="IP5_2-K_N_lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456:SF2">
        <property type="entry name" value="INOSITOL-PENTAKISPHOSPHATE 2-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06090">
        <property type="entry name" value="Ins_P5_2-kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="409" mass="46208" checksum="3ADBC7AC9A2B9FE5" modified="2025-10-08" version="1">MLAQKTYHSVPALDLADTSPDHWKYLSEGGATLVFSYTGPQDERFHNKVLRLGKNNTVVEDEDSLILFQTEVISRLVLQKHLAVLETVLLSSSWLESLSSLCKKARPDWRTGDIDTNRTKGFLAPNLVSSPISVEIKPKWSFLRPGLRTCRFCMHSSCRGWITSYCPLDLFSSSPARIKNALYALYDAWVDGAASQNNFRLFADGRLMSPEDLLPALRGLGMLHSSVLEEKGIRELVVETLLVSFMKSESLELLKTLKNLQRTLDGLGIEGLASLWDNVHSLDRASFGGGFPQPPIDDWKFFVTEYLEPQGSSVPPQALSGETQLRYNILSYLLSATFKDCSMMIMLPGLLHESLPTSLFPSRITLIDLDPKRVERLQKWLEQDRNIMQEYTVSSQTKSEKRCVDVWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNT0</accession>
    <name>A0ABQ8VNT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_296330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="256" mass="27668" checksum="E86A3A9719047CE0" modified="2025-10-08" version="1">MASISLSYADRAKNAQNIRSPIENTVHAISVSIPESTSTSSPFSSNASSRSSTSSNTGSSTVISSSSTDVDADITAPTTSNSSVIVESDGECNGGQQEQKKQREREREEEVSRITTRKPSVNVWEQRMNRGSASSSFPLISSSSKSSTTNSAFIKKDNDLSVVKVRPTSNNWSARPTPASPSRLVSLDLRNSNAWPEVGVGLSSPSKDKGKGKLSNEEVSVVQAKPPYTRMNLLFVSNTNYSVHAFQKTKIRKMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNU1</accession>
    <name>A0ABQ8VNU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diaminohydroxyphosphoribosylamino-pyrimidine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_820602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF162">
        <property type="entry name" value="RIBOFLAVIN BIOSYNTHESIS PROTEIN PYRD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18785">
        <property type="entry name" value="Inv-AAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="177" mass="19254" checksum="6333104D6A9BB591" modified="2025-10-08" version="1">MRFPPYTVYPMTPEGQHLQFLRLALDEAKKCTPTPTAFCVGCVLVSCLEAEPIVISTGYSRELPGNTHAEANALSKFCSLPQDQLSKFNASAQSHADILASADVYTTMEPCSIRTSGLPPCAETLIDARVKRCFIGVGEPDDFVHCEGAQKLVNAGIDVIWLKGLEEESLNVARRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP14</accession>
    <name>A0ABQ8VP14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATOR2 complex protein MIO zinc-ribbon like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_819445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16691">
        <property type="entry name" value="mRING-H2-C3H3C2_Mio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21720">
        <property type="entry name" value="MIOS_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="3">
        <location>
            <begin position="1274"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="667"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="803"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="893"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="826"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="894"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1401" mass="153773" checksum="DDF9534D9AEFE005" modified="2025-10-08" version="1">MPVQSEKRVLWHPRHSNKFVVGGGSQITLYELSDEQPEIRQVTSQHELQFMKCFAWSPASIPSDIFAVGHTSGRVDLLRLEASRYSQLGRDENVLSSGPILSLPVRNQRSCNALAFCPSDPNYLAVGLDKVRGDSSLVIWDVQEEMGVFRTTMNPFDNANVVTIPHSNEPISKFNTYPPIPRTDHPVRTDQRIVQAHAQTELISSLAWLPQNTHPYLLLAGLSPRWLRLFDIRNPAGSGAGASYVSSIATKVTGIATDPFDTTRFATWGDGVVTVWDIRKLHISRIHSDSTNATPSPTPLLTFSEKDAGFDSVSSTLATGASKPSVASSSASSKTRGVSATDFPNLPVVQHSTYMTAEFSPSRRGVLVTLAKDANYVRLWDVLEVDNSPITREVDNENIIKLQDKVPVGRKSWANLPWGSSGTSTESKNSSPIHEEEHREQSQHPMLILYNTRKAFTRSISNPLCSFAAVPPVYLSHQTISKIVVVSQLGEITVQSVHDAPQALAWSSRGDMLYGPLQSVDKDDVKTGFGVVHSYHEEQEETVKDEYVHDTQTSPSVTRPSMNQKPYPASEPNEFHERGRPRNPVTFQEVPPSPALFGRGDAEGFPALSRSISENPVSANLAATKPTDGRKEEEKKMTFSPAAALRVPLRPTNALSSLMNVSAITHNEPSTSVKSQSSNPPTPKYQSMVNGGKASVVHAAANDISVLMRRRAIRGYSIRDPLRNASVIRELSHFGNPGAGVEFEEPSAFRSKESEMLADLWEWIHHSQKFLSSPTPLLHGYDFSFAGVWGIWDGPPSIGGSGTISRYKDSNTHHAEPSTNMSEEYSSNSGSLTSGSVSSSLTGSINMSSGSSMMFGGSSIISGNIGDAEATPVHRDRLELPLETETASLYPGFDRSRRVKPQDETSTSRETRTRSPITEPLTNDPEWRQALLELLARTEEPSSASRPPIFPYVSTSRPLQRHVCLHLIGWGFILRDDSLMAEVRRWERESEGDEGYARAAAWLVFSGRYGGGAGVSNEGAVHGEGAIECLLRSEDESHHMMSGVIAALVPFASATLTTPNSSSKLALPSTLLEHYARLVNKLQDSYLRALLTHLTAISSSVTPSGEHWLEILHDEEDLLPFYERLALAFCFLDDAALTTYLRRCREHALGKNGGDVDALIVTGLGTSEGREVVGLWLDRIGDVQSAALLCWTGLSSSLGRERIAKLTSGLKAKGQTSIQDSRVARWVEAYRDFLDSVKLFHCRVEFDIERGEMLQIAKDQKITSLAPRQILIRCNYCNKTVTPNAEISLSESNNLGTGQDSIPKGKPTTCPHCGRALPRCSICLMILSIVPDAHREAELLLDHSQYQDNDTIDDAILLCLGCRHGGHASHILQWFFGQDGAVLSHRVCPVADCAHQCGNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPQ7</accession>
    <name>A0ABQ8VPQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_894127</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="156" mass="18106" checksum="39FDD2D7426C7200" modified="2025-10-08" version="1">MSLVVPEAHQQFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNIVCKKADVDLNKRAGELNSDELERIVTIMQNPTQFKIPTWFLSRQKDIVDGKDYQILSNNVDSKLRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVGVSKKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ26</accession>
    <name>A0ABQ8VQ26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_944214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="190"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="53392" checksum="3281290345311652" modified="2025-10-08" version="1">MMKMKATRLNMRTNLTQRERLKESVKTMHRHQIIFKLSESGENKQTLKKATRHQAQKLRSELPQVRSHPLPITHTAATTAVNQLPQVRSRPLPITNTAAPTAVTRVHSRSLSITHAANPTTVSQLDTALAAPAWLECTNIHIIKKVRTFTLAKTGQPPVMLQIIDKSIAYGKLQMIFNHEYSPLHTFKIKQLAHACLMEMAERSGHDGNNNVCDRLERGDHDSYSIPLVTYVSRRIGNERADLKAHSSTILQAFGLVNHAGCLEAGALARRRTYYYPEMFNGMPDYRKPFEHPVFASFLREAFSSSTYYSSIVRRNFHLFKSSNSKKSEELEVTKGMVALAAAAIHACLHDYSTGMKSSFPAPELDGVWGLAIDILEGIESRNHSKYHRLMHKIFVEATGNSMTAQDGWCNQQHLDAVDWDAIENSDDDDDSNGDDESRVYPNPVGDSEDVVSVHSGNSHHTEASTTPALATISTPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRE7</accession>
    <name>A0ABQ8VRE7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_755706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="243" mass="26557" checksum="665D4F5B7ED61880" modified="2025-10-08" version="1">MIFYCQVGLLNGRSEAGHQKLASEMLHNVVIGAVGVENAYFAAFIKGFLLPGATGFNLADIVRSFFGGPEEFVRTAEASTIRDFKSLDIRIVCSLGNQSLDELAEALSVAGAHFAGKTFEDIIKDFLISIGAPCPQLLAVTKDRFSPEVKASLSGLQSPTFRMRLMCWAVTGAPRVLRDGEPMQIILVDDNDTSYLPHGLTSYLIQLLKDTYNPDAEIKNAQVAIHHWLLIQMLDSAGTYNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRT0</accession>
    <name>A0ABQ8VRT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_908629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046065987" evidence="3">
        <location>
            <begin position="19"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="365" mass="40270" checksum="DF84706AA55DDB64" modified="2025-10-08" version="1">MFLPATLIALSWFSAVFAGSANFGDSCSVSNNRLQVGTYQFYTDCNSVTYCASNGTCAHRGCRKDDFPFGYPQDSNNLPPKCGKNQFCPDEMDDCLNVLPVGSACQMNRDDQCEGPPNYKDLLDTTNRGLNVNGSVCLNNVCMWANLTENDDCVVQNTAYIGYTASGDEFIDIVSRGNCRVGLYCDAQSLKCFQEKSLGVSCDADKECSTWNCMSSGVCGTDQALDRHLSSWVYAIVGIGIFVGMFGTLIGLFCLHTKQRDAERERRLRYWREQNAFHQNLSQMREAARSSILSIPGIGSSTRSTLYGGNNSDDSHAPMMPNALGQPRTSRLRNHVKDDGNSEDDDESLIMQQPVQSLRGDDGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRX0</accession>
    <name>A0ABQ8VRX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_816102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046654271" description="Fibronectin type-III domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22091" checksum="962828F3F9F647F0" modified="2025-10-08" version="1">MAYTPLIHRALVTVVISWLLLVVRADGFMQQSFSFSWDSNLAVPVPVTTQCDTLNIQWSRGTNTGPNPVAPYYLQIYTSAFVYPFIVAAGSNLNFNFAVPFGPGTIYQICMFDSQGNTGGCQATYTVIANTSSSSLSCSNSTLSFPLGPLDVDAEVASGALSQYGWIDQCTDITVTPKNGTGPYTFTVAPSLHPPLNITSNSASAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRZ2</accession>
    <name>A0ABQ8VRZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_893745</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="560"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1031"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1073"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1156"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1250"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1282"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="339"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="737"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1037"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1341"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="427"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1588" mass="176497" checksum="53A7EBF29DCEC60D" modified="2025-10-08" version="1">MGSQVILNPDSLVNITTSLSAVYTNSLIIPLCFAAASILARVEPVRRLFRRNGTVPNSEESAAPVHPENLVQELNAHIGSHGGPLIYTHMLIRLVGTLALLGLSITSLILDEVRRNGKQGLELLEGQEDIVDSLGKWGKKHPKKKYGTHYTKREWLEAAMCLTFLYTSLLALISVTAKPKWSKVVTRHLNTVLLATFSVYLYRDVYPLITFTLKPKDLSEGGILWAKITLLAVTSVVIPLAIPRPYVPVDPKNPLPEPSPEQTASIFSLATYAFIDRLVLAAYRVSHLDFNQLPPLSDHDSAEYLKSLSFKHLDVFSGAPKRHLFFGLIHIFRSAYVQLAVMILVHVFANFAAPIGLNRLLRYLEPGGEMAVVRPWFWILWLFIGPIGGTISIQWYVFVTTRTLVRTQAIITQLVFEHSLRIRVKAETADSSGSSTSSSPETLTPDSASVHEGTVDGSDTIHSISPSEAESTTVHSSTSSVSSGTDKGKAKKTDKRIKKETDDAPSSDTNNLVGKINNLVTTDLENITDGRDFLFVIIYIPVQIVLCMVFLYAVLGWSCFVGLGVMIVSFPLPGMIAKYVKRAQEKRLKKTDARVQSVSESMNVLRMIKLFGWESKMESRIAEKRDEELVWIRRRQILEMINGIITISNSLLFQSVIMKQTIHASVIYSSMTVFDMLREQMRIIFRSINDTVTAKVSLDRVSDFLKNTELLDSFSDKAPESDDYFVPADAVSDPQKIGFRNAHFTWSSDVNGSLTPSKRRFTLRIEGELLFKPKCVNLVIGETGSGKTSLLMALLSEMHFVPFGPDSWYNLPREGGIAYAAQESWVQNETIRENIVFGSPFDQDRYNKVLYQCGLERDIGLFEAGDATEVGEKGLTLSGGQKARITLARAIYSKAEIILLDDVLAALDVHTARWIVDKCFSGDLMEGRTMILVTHNIAVTRPIAGFVVAIKEGRIESQGTALEALGKDPALAEEANKEQQIIDKTGEEVDEKPPAEETKADGKLIVAEEIQEGHVSWSAVKMYLTSMGGRYTWAFFFAFIFAMFITEILNAFYTWFLGYWASQYETHDPASVSVSHAVVTYSIGVVIYIFGTVRASRAIHKELIISIFGTTLRWLDTTPTSRVIARCTQDIRAVDGPVAMWLQAVSEISMMMILKYTAVVVITPIFFFPGVAVAFLGAVCGQVYIKAQLSVKREMSNARAPVLGHFGAAIAGLTSIRAYGAQEAFKAESLRRIDKFTRAARTYYNLNRWITIRVDVLGALLSCFLAVYLVYYRGQSASNTGFSLNMAVGFSSLILWWVRTLNEFEVQGHLERIQDYISIEQEPKPKAETVPPAYWPASGNLRVEKLSARYSQDGPKVLHDISFDIRSGERVGIVGRTGSGKSSLTLSLLRCIFTEGTVYYDGIPTDKINLDALRSNITIIPQVPELLSGTLRQNLDPFDQYDDATLNDALRAAGLFALQSDMNEGRITLDSSISSGGSNLSVGQRQILALARALVRGSKLLILDEDYRTDSIIQDSLRNELKDITLITVAHRLQTIMDADKIMVLDAGRIVEFDSPQALLNIKDGKLRSLVDQSNDKDSLYTMVTRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS32</accession>
    <name>A0ABQ8VS32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_789623</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4499174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="62540" checksum="E7B85BAA59D8CFB6" modified="2025-10-08" version="1">MTFTDFQSFPLLGIVALSVVLLQLYLRKKYKTLDNVPGPGSASWITGNFKQVFNPGAWGFHEFIAKKYGGMVRLHGPYGTKSLYTFDAKAMHTVLVKDQDIFEESDGFIESNLLIFGNGLLGTLGHQHRQQRNMLNPIFSAAHMREMIPTFFQVSHQLECALRNRLQSGPPTQEVDILSWMGRTALEIMGQAGLGYSFDPLTDDESFHPYSKAIKELLPTLMRLQFWRMNVLQYVSRIGTAGLRRFVVNLLPWKDLHHIRDMIDYMHSIAEEIYESKKRAFEMGDEVVSQQIGRGKDLISILMRENMKASTENRLQDNEVVGQMNTLIFAAMDTTSSAMARLLHLLSKHPDAQDKLRQEIIEAKRQKDGQDLTYQELTELPYLDAICRETLRLYAPASNVVRFARQDGVIPLHKPIIGLDGAEMHEVAVPRGTTIFVSIFNANRNPDLWGKDAHEWKPERWLSPLPESLVDARIPGVYSHLMTFIGGGRSCIGFKFSQLEMKVVISILVETFKFSPSDKDSKIFWQMNGVTAPVVGKDKHPQLPINISLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSH3</accession>
    <name>A0ABQ8VSH3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycopeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046067921" description="Glycopeptide" evidence="1">
        <location>
            <begin position="22"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="15768" checksum="3143BBAADBA1A56A" modified="2025-10-08" version="1">MFTSLRFAALVAAALVAGAQAETHTVSFTNLCGRGVPTLKANGVTLSTGGAYTSNGPLEAAIAYLDVGCGANGEGCTMVETTLVNPTSPGSGSSTDITLISPHTFSVTTGFGYYDGCDGAGADCTSASCSTAFHVSTDTGVQVACQSDNVNLAITFCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSH8</accession>
    <name>A0ABQ8VSH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_754730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="125"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="569" mass="63612" checksum="41F976EDB44DC491" modified="2025-10-08" version="1">MVADIFRDATVGQLFNYFSNGTILPYPEERSDFTVPARFLPSQTPTIIADESDDVQKPEPESQKSKEEVLVTETETSREITLDENEGLGDLEAQKINDDPYLVTWYGVDDPENPKNWSSKKRAFVGFCVTWMTFTSYVGSAIYIAAIPGIMEQFHVGLTYAELGLTLYVFAYGLGPMFLSPLQELPKLGRNTIYMCSMALFIIFQIPTFVAPNFQTILAFRFFTGFFCSPALATGGASMGDMYPVSELAMLLALWAEGVNAGPIVGPIIGGFAAQAKGWKWPFYELIWLSSFSFVFLMLCLPETYEPTILHRRARRLRKLTGNQQLTSQGERDAKEQHLGLVFKDALLKPIILATEPVVLFCNIFIGLVYAIFYLWYEAFPLVFTGIYHFNLGESGLPFLGFLVNSILGFFIYIAYLKYHFQPRMMKAMAAGKPSSPETLLELGLIASITIPLSLFWFGFTSRASIHWIVPIIGASFYLFGIFFNFQSVLIYISSAYPAYAASVLASNALFRSTAASVFPLFGRFFFQNLGLGGGSGLLAGISIVLMPVYYALIRWGHILRRRSKYASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSN7</accession>
    <name>A0ABQ8VSN7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_756344</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01514">
        <property type="entry name" value="Elongation_Factor_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="29"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="788" mass="86499" checksum="DA919405D5ACB05B" modified="2025-10-08" version="1">MQPRLWFSFVRKCPAPCRKISTSFSHDASKIRNMALVAHIDSGKTTLTESILLQSSYISASGSVDTGSTTTDFLPAERERGITIQSASIPVKWKNWTFNLIDTPGHADFGMEVESASRVIDGAVVLIDSVEGVEAQTKGVWKQLDRYGVPTRMMFLNKQDRPGASFKLSIRSLLTHRLHPHPMVLTLPIASFDPQDYMHAEPGIQGLVDLLKWEIWRWNEAGESTCYPLPTDVQALEKLEFIPSHHPIIPQLAPARTQLLENLSMFSEDLMETLLALPSEPSSYLGIKYPDIIPHLRKSTLENKILPVVCGSAIKHIGTSIAMDYVGELFASPLDVPHDSAKNAPLRMLAWKVSWDQKRGWMTYVRVYSGTRKLTRQSAVLNATRNQKEKVSKLLLMYASEPLEVDELPFGAVGVVLGLKFTRTGDTLVSPGAPPSARSVMQDIVPPKAVISASVIPHSHSDLEPVQNALESLSRTDPSVRYDLQEGQILVHGLGALHLEIVEGRLRSEFQANFELGKRRVSYRESLGSNYDPPHYEKPLVTNNDKADIAGTSVVVALDIRPLQDDEEGSPLWDGNLVLNKAGVAIPSPESSSTANPELLIASGIATALSSSPHSSLPMSHLRIQIREWSTPSPLSLLTGASAIIMRNRIRKAGMGPLMEPYSFFKVSATEDTLGKVVKDLTEHGAELQDLGDGISDGMDEVVGYPVEGNYIPPDMLSPSSSNLTGSGASPKLKRFVHALAPLSQMLDYNSRLRALSGGHGQFDMVNAGFRVVAEPRKMEILREIGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSZ4</accession>
    <name>A0ABQ8VSZ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_893993</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="7">
        <location>
            <begin position="66"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="21631" checksum="ADEFD27BB18214DD" modified="2025-10-08" version="1">MSGDKSEKKDKKRKVIETDIADEDVQMEDVKQSSKKVKKERTEIVIPLEDLSPLAKPLAQKKLVKKLHKTIKKASKARQVKRGVKEVVKGIRKGEKGLLILAADISPIDIISHLPVLSEEAQIPYVFVTSKEELGFASSTKRPTSCVMICPDQKKKTKRKEGAEEKDDDYRELYDECYKEVEKMDTQIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTH2</accession>
    <name>A0ABQ8VTH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_56949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="705" mass="76629" checksum="7F549035DED6F163" modified="2025-10-08" version="1">MAEPSVVSSSRHRSQPSRTNTSTRSASTQQGHISSQSPSQPISMPMPMPSTPPVLPNSQGTTELRRSYYTTNPDPDTEGSVEGDYVNIPAVGIGGQAMGFNVQPVEVEPIPRRKGGGRFIGGFVRSLRKIPRTMFRPGHGSNAVVPETPSQPAARAPLPSYMLTPPTPAIPGQPFSYLDENHVPETPDIFPVTSPHPTRIELDEATVHSPERNADRDTTNMPSMSRHTSHHTSHHTSQNHNNPSTNRNSFAYPNSYHDPPSVAAHPQPSPDYRRMSRHTGDESVLGSYSAGTPSFSTELDRNPFRVLKALVNMPWISHDRVTVDYSPGMEDSRGALRVASPSGEKGKSKGSKERQSTRWSIVEQGWKPWKRTSVFLTLDGRIVSPEQGPDALARGDARKGKMYVPVNKPETSWYSGGHMIKVTRNKRSGIPRNRELDLMSSGSEPGARSSVASTPRASRVSARRRISRSTLTSPSSPTSPPPIRRPRNRETFRQTPRRHSRRLYYVNNEYAFLDPGSTPGSSPILARRSNMRSREVLRDRHRPIRRRYSRDIPQLPTQQPLVPPVPPPASPYPLSPLVFVQSAHMDSPSGGADPHPHPQTGSGMPVPVYGVTPMYMSILPGMPPPPTGSGVGIGESSPPGFAGRGAGGGYGSGYGVQGYAGTAPPGSGAYTYGYAYPYAPSQSPPPPPQVHHNGETRKSPLNTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTP1</accession>
    <name>A0ABQ8VTP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_813310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="383" mass="43732" checksum="4495A22895C147B8" modified="2025-10-08" version="1">MKQNTDTIKWPFTVQGPDLHKIASRIIQYGSDGYVRMHDAPLKSNVVVTLHGWDWEKKDHSLKGFKIHDGFDFVSAANERILWDGYDGNIGLGPRQGDIQTEKSRSFLASLTATRQILDASMFIIRFVHPDDLDNAPLNCNLFNVISFGPGFPFQAPVNPDAYFSSPIPTISRDIADMGRPERWTFKLLRIGICSVDRNDYSWIDMDSPEKRSSIIQGIDILMDTATPMTVLPDYVVSKIQSDENWLGSSRQTRLDLSMNDKTYTRLARKKIQFEFKGEGHHPVGVTVSAKSFMVWYSKVEAGDNPKLHLCSIKGSYDQKEFVLGQNWYWAAIVKHVSPREKQKFPFVQVMPNGYFTDYDTNKTVRPTDMILKPLPPRLYPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUA9</accession>
    <name>A0ABQ8VUA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_812744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="25164" checksum="39B52EF4924E3908" modified="2025-10-08" version="1">MQQYLPSVGPTPESLSRSRRNAVDISALTSNTRTSPIPSRFGRRNAIDYTSSLVKSDWWHAGQPHAFVPRHNYGANPAVPFSSAEHVQAGVAMSELENHQDLNHSSALITSFLPRDWMPKRPFVRLVINWPGYNHLQIVKKLFLFSHNGNPRTLMEVAHDIADFYRSFIHEFHTAFNSAEHGAVRLGPNYVTFGHLRLLGMQLCNPSSGDWIADVSYVQFRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUH8</accession>
    <name>A0ABQ8VUH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="7">1.1.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_753349</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2</text>
            <dbReference type="Rhea" id="RHEA:21252"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:16782"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the L2HGDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.2" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104:SF4">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="9">
        <location>
            <begin position="28"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="457" mass="49900" checksum="B1E98FB773B915F9" modified="2025-10-08" version="1">MKQPVRGLAAALNSGGKFRFKAPEVVVDHLVIGAGVVGLAIAQRLCESFPSKSTYVVERHARAGEETSSRNSEVIHSGIYYPADSLKTRLCLRGRDLMYQRCRALDIPHRKTGKLVVAKDNQRPYIENLHMKALRSQWPPYSNAIDSSPVLPTRLISGDESRAMEPHLSQDISAALWCPETGIVDSHLFMESLEHEISESEAGNLAYATRVVRLDPYRSSKEMSVAERGWVVQTVTGNDGNSGTESDTILARTVFNASGLSGPFILNSLLPPERRIPMYYARGSYASYQGPGVSGISHLIYPCPDTGPNAHAFASLGTHLTLDLNGKIKFGPDIEFLSPPSSEDSEENMDYWTRHLIPDDSRLEKMHLAVRQYLPEVVADGLRPDYVGIRPKLVPAGAGFQDFVFRIDYPCQFGGGGTVGKGPMISLLGIESPGLTSCLAIAEYIVNGLLGSTNPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUI6</accession>
    <name>A0ABQ8VUI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyruvate/Phosphoenolpyruvate kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_914921</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="35"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="286" mass="30667" checksum="050FA78D4E026AF4" modified="2025-10-08" version="1">MSSISSLDVPSTETLLGLQKVMADARNPRRPVVGSWLMLPGASLARMVAQMGYDFVLVDCEHGNLADADMHASVGAIAAQGVSPVVRIPAPENWIVKRTLDTGAHGILCPMMSTSEEARKLVSYAKFPIPKSQSTPATTSGIRGVGSPFAPAVFGQRMDDYIASANRNTFIAVQIETVEGLENCEEIARVDGIDMLFVGPNDLCSSMGYPALEHASIPEVQDAVQRILSAAKAAGKYAGMFCTSAEQVEARYKQGFDFMNLGADVVALAMWNAAELEKLKNIRIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUL9</accession>
    <name>A0ABQ8VUL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_899910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="408" mass="44900" checksum="F94D7E464A2B8CEA" modified="2025-10-08" version="1">MGAFGESGDSGCIVEAGLRRGGLWRTREVLGRVKQFHGELRRWEGGSSESVGAMGGEAEQDQLALTIESPSRIQLQLFETIFNTGKPLVLYCHDDPLWSTLAEVALPCSNCVKHPEAWKVPEGSPRCSSCTGKKTCSLGKILRHCYFSHRCSQDLAYSRRFLELHGSPAQRVSWSIPEDVWRRYDNRLHSQISSTSILMELNMLDDQDTQAVDRRELARFQRAQEQEAALALAAKRKRAPVSPPRDGSSKKRRSTKIRSQPGASEIIAGEVPRVVRLVFPPARPPPPPSFPSPPRPSSSDSVSTSRVAPVSRQTGSVRDPEPLVQLAEVAGRQTGFATRSGAQLAIPTPSAIKGPQEVQVPNVPSSPAMPAANCPALVPRVLAQHPYRAENECLIAQIFFHKFYKTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUN4</accession>
    <name>A0ABQ8VUN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045711212" evidence="1">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="225" mass="24423" checksum="EA1A2DA90F8FA285" modified="2025-10-08" version="1">MKFLKAILLVLPALSCLITASALPVYPNKLAARSTGTYYHAIEVIEMSTNQIGHHPGKPKNKPGDFSNQWGYYMFPTKVDAIFWGNQFKTPKHESGKGQFAVVELEWSLPTGVAFYEFSSPNDQWEAFVTANYDTDATLGQPRLAGKDYSAIQGPMSFKVDTSDGGGYTQEISQVTGKPLTQLAIVALDGLEGVTVKNVEIYNAADWQDGPKPKGVALAPKSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUP3</accession>
    <name>A0ABQ8VUP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Manganese/iron superoxide dismutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_753377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="3">
        <location>
            <begin position="124"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="3">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="29983" checksum="A99718D0B7F47F85" modified="2025-10-08" version="1">MHRSPFIVRGCRRASSSSTRRLHTAKPLPYDPAKGLGDFLPPEALKVVGVEYQKGLLDRLNDEVRGTEMSNMSITQTLISSAPDRTRVLAFNYASLALNNHFFLTNLLPPNPPHPSHQHLLSPTLAQEIRTQHGSLAQLKSSFSAAATGLFTSGYVWFVTDAAGNTGVVPTFGPGSVLVRSQMYMGYLKGLGGRVGRESGGGGIGEGPDVGPGEVLKGTYGRGDTLYPLFCLSVHEHAWLSAGYGVWGKEQWVRAFWDVVDWGKVSRAYEYFKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV42</accession>
    <name>A0ABQ8VV42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_478278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="156" mass="16893" checksum="E3C35F8BF33B8BE2" modified="2025-10-08" version="1">MTTYSAFFSSGLLAAPHMSSSHSMYNNHIPRHGDAPPSLLTVTDALDDTSDVELDRSTTPTLTNIETSMHQTQRLRRRRSSLTIGTSPINAIKSPSRAAGNALQLQRHLFTTPGRSRSGSTSSVMSIGEEVNSNIASENTSLYRRMRSGSVGSVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV66</accession>
    <name>A0ABQ8VV66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_726943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="60" mass="6848" checksum="F1D5FD7982ECE1CF" modified="2025-10-08" version="1" fragment="single">LVRAHVPKVYKQVALILDSPSLVLGRAVAPVRFLPRSIYFADCKLYIRTRLLASAFSNFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVM0</accession>
    <name>A0ABQ8VVM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mini-chromosome maintenance replisome factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_811437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019140">
        <property type="entry name" value="MCM_complex-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13489">
        <property type="entry name" value="MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13489:SF0">
        <property type="entry name" value="MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09739">
        <property type="entry name" value="MCM_bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="596" mass="66608" checksum="4A7A3DA5C4449E60" modified="2025-10-08" version="1">MVSSVPFDVLNDPQAAIQELFDQHLQSQSSIEFHSVLSNHFREIFNQEERLELIPHLHSTYFARSSSDSSSTSPRLVQFRGMVQDTSASPELYLSQLREGKYGGWGAHESMDEHIDYSNLRECTRYWVVSVPGETEWAGQTRTDTVLASTSKNSNRSADHKFPLSSTAHIGVHTNIYSVQSDPDLKSTDIATFVGLFEAERDTLHVLFHLHENMAHKPYRVYPLTMADTHESTSLEKGNRALQRELVKWIADESLAGDMDAAEWVLLSIISRVQSRHPPIIPASLTLARFPPPPAKVVPTASTSATPDMHRLATSTSTPALYHVLSLLLPILAHVPLSLPLLNDEVFFPESKPRPRSEGADEDPEDELYSGLLQLAPSTVCLITDSSVTEGQINDRGVRNLRALQEVIRNQTLEYVFPYSVFRFETDIGYIVCTEGKKSALVETHTTIPLKPVDSLSTSELQQRLYKSPDELNLPPIEKLEAWRKLIGGAIAMQTANIVNQSSLSPPPPVPVGGIGVSNAAAELIQEEFVQERQTEAQRSKSSVERKAQTTITPDDLIHRMLMTKLLALSTHEPEVSIDIWKRMKDLESRRLARMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWT9</accession>
    <name>A0ABQ8VWT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_977410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="3"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="436" mass="50551" checksum="5AD9D5E59CC8CC65" modified="2025-10-08" version="1">MLTTLFVAGLGPTTRARELGEVFERYGRIARCDIMPPKKRRTHNSNNPYAFVEFLTSRDADDALKSLNHTYVEGYLLKIAWAEHPPNQDDPHAPLSHPSRHHISCRSRSRSPIPSRRDVSSEMTRIIPNLHSSSFLEHHRDNNHHSRQISDIASRNNDIQAYSNYHAIDTERRHRDDERYNHGYEIRSDPNHKRNGDSHERLASSWDSRHYEPQQPQNIFPERRSRYWDPEPVPHRERRKEDSRSSDYQHTDHRPVHHKHTRTSRSCTPPSVRTSRASRYASTRAGDASFALAAEKIDSASREISEKRNWDRPSTKLTEVGTNLYHSSRQVRYTDDDSTQEFPPSRSRRSSSYTNRRSPSPVTQTRIPADQTPQSPTPQNMQFTEHVDYARTPPGPPPPVEMVDVEADNYAKTPPREPFENIGHEAEAKVHEKQDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXS7</accession>
    <name>A0ABQ8VXS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cation/H+ exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_893263</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562">
        <property type="entry name" value="NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562:SF3">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="38"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="475" mass="51086" checksum="313BEB513DC8FB64" modified="2025-10-08" version="1">MCVYTVPDVPILLTTFSLLYLLNVAEAILNFLLEAGRLGSLVLGIVYGPEVTSIVPENVLQTLLILGYIGLILLVFEAGLSTNIALLYDNSVSSILVGASGILLPITLSILVVHFGFGYDILPSFVAGASLSSTSLDTTLSLLKPEFRRTRPGIILLSAALFDDVVGLIIAAIMQTLSSNARGSVLWQDIVRPLLVSVAFSGSTYLLVWALQLLMKRMPDHWKRDIYRAETQLFLQAVFLAGFVAGAKYAGTSELFGAYLSGVLVGHIFHSPPETVQPSARSASIESVGESRVSLALGAPSAGIYTPHLTFDIFVQPILRYVLSPIFFASIGSALPIRTLGSVDGSSRVVWRGFVYALSMAGAKALTGFWLLIPPTFLTFQTICPPWRIRNRHRQSVPDPLEELLMSPIRSAILVGLAMIARGEIALIISQIAGPILTQVSQELYAIVIWAILLDTVIGAVGVGIVLRQNPKASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY30</accession>
    <name>A0ABQ8VY30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="484" mass="54751" checksum="44E39B6D7E905EF8" modified="2025-10-08" version="1">MSRYPAQVSSAQLLLPTWQQALKEDAREQFSEIAVIEWLAVFIIDYPIGRDHSFHKQSTHLKESILHSQAHSDLESHCYRNEFSAFEAGEPEASFNAATVIKNAWNALDKIKALSQFKVPGSRKASQIKAVERIINAFTIYLIDAQLISLSALTRIDDAPQPSLEAHLIACDATMHSIELAANLVDITRQLASLRFLCVSLSENFSQEYVILKGEYMAISYKETSAEPSLTLFPRKFSLSNMHSLQRQVSNQESSTMSTGINAQMKTLDAPDKLLEAQVNQQESFKDPAHMNTQTQFQSGTRGLEEKVMDIKQNNLTQSKPRPRPRPHPYTKDRESTAKDSNDAKYYRFDGSGLSPDQKGWVHLHLTTWFDVKNNPEDTRIFIEQISGEFLMKFPANDLVQEGSALNNAHFQAYTLTKIKKVVLQVIVHDVTALHFERFFKKARAFKTGKAFPHPKLSLNADWHAMLITGIANSGYQAWSSYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYC6</accession>
    <name>A0ABQ8VYC6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_913404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_7G04540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="58077" checksum="9D984C11573D6921" modified="2025-10-08" version="1">MDSKDLFDISNWACIVTGGGTGIGLMIPQALVNHGARVYITSRRKFVLDNAVVTWGSSLAHPKGRLIALECDITDKKSIQKLVEEVEKGDESAKQLSEELFGEDLVKCEDVYRTNVIGHLFTTAAFIPFLAATATVHPSRAAIHLTTLLAQELRRDGANVNTIAPGILPSEITTQESDEANKSEIPTGDDYGERKAIPAGRPGMDEDIAQAVLMLACNQYAYGQTIAIDGGYLRHHPRWNAVIVSWIVTAWCTTCLFFATTNTYVRAGLSTGAFRSTIIDSSMTFSPASSIFLLVLLMHSVAVYSSPVNLALLNKREPGTIDNNANATHDLYRRVDFDKPNLILGYLAVPQKTAEEFNAHGFTAIPVPRSSNPLGNDGTYVEATAIPDKHLPEESSQCAVFINTLEMVRTLRGFVDDVKSPAYNQPKYLTYFIEDLQKEWKNKGKHFVPGPPLLAARMQKGWTQLVVLVPYHYLLKSPSNPKQPSGENHLKLSLKCTPKGTSMDVKLPPPEWEQWGFEYWPKGLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ59</accession>
    <name>A0ABQ8VZ59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_976616</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948:SF3">
        <property type="entry name" value="FI21118P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="99"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="533"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="9">
        <location>
            <begin position="653"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="486"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="588"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="630"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="486"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="597"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="635"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="755" mass="82313" checksum="C05864F00F28B8CF" modified="2025-10-08" version="1">MDYNDNREWDRGKIPDTPWYPPDSRQSYHPREDDHNAQGKRRKFNDGGYQGYDGPQAHEDYKYDANYTRQGPGFPQDQSGRGGGPGHPKKRLQPSEPSPHVIFLGLDPDFTESDLQSYLNSRGCSVETVTIIRERSTGSSKGFGFAQFSSSEHARAFVDPLFPFVQVPPPASHGATATAAFYKSLETGLPHNGRRVKIDYSQSATPHEKGRSRGNTNDGTRDIGNVQAPVLLFRGLDPLSGPQAIHQAMRNSSGVGKEGAQGMKRIILIKDKVTMASFGFAFVEFIDTLSASAVLAATMSPQIHPAGFRISDRPVAPSFAHPDSFQPIQEIMLRDEACLVSSLALGGVEGTYVRYWDESSMVAVLEFQVATPQSSTMPNAKDKKEKKKKDSAARPTAPPIPSALPVSDKPVTLSFNKGPFKTSISLSPAVKPLSLGFSADDLEENDDKEDNSGIGIKVNNSKGVASHMASKKTINNINKWNQVQEELSSSTKTNSPTLVAPTETPTVTSANASAPAGPPLAEDAFEFADMNSFACLLCSRQFKSVDQLKRHNKESDLHKARSLIHSSLVVIKNYEDVDLRDLARQKVSARQQAKVSEQPKYRDRALERRSLFNQPDVPVPDVEAIKLSKRKQVEGPPPPPPPPPQPLNPGQDGNNVGNKLLRMMGWKEGTGLGVHGEGRVDPMYDNVFYLLLMTDFLLSKTAIYTEGVGLGASKGKEVGKFTDASSGYLSMAQESVSGTASISDNVENTHGMNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZB8</accession>
    <name>A0ABQ8VZB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_914756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="52013" checksum="3C65D42C6E3E1395" modified="2025-10-08" version="1">MNPRCKDVAPFGHNKCFILRLPIELQTQIFIECASYPYGQLMIEHEAPQVLLLVCKYWRDLAYATSRLWSSFEIHFGTWEQNFKGTEGDARILSRVRLWLRRSGNYPLHVKLFYKPVASRPRQGTLSHLMSEMLALLIRYSSRWQDIELSMPSSCFASLSSAAPGLDLSSLSSLVLNSIPSTHSDFLDVRNLASNCGKLTRLHINFESGRVLTLDDCGVIFAQHPNLSSCKLYAQCLFDGSSEHSGHAVDKFILPALSELHLTLYSRSNHGSNNSFSPQTALTMFLNRLELYVLTSLRFEWFVDNDRSSWSSCHPFFVKFLEAVEPTLETLSLGYLPLSEEQLIDCLRATPYVTSAELLFSLGEEIEGPAITDKLLRALTFIRRSGSISTSEPLLCMLQSLTLQCHGKVCSEQELVRFLESRSNKQPHTLQTLKLRTQTPILSGESRWIDSGINVTEVCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZH6</accession>
    <name>A0ABQ8VZH6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sugar phosphate phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_810212</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:35603"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:28002"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="domain">
        <text evidence="7">Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039763">
        <property type="entry name" value="ARMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260:SF6">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="8">
        <location>
            <begin position="22"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="493" mass="56632" checksum="4A013BA24C0E706E" modified="2025-10-08" version="1">MVFQPPFPSYDPTDKSGFSYETVVRRWPVILTGIVDQLHRENHDLHLVVQTPDDDPERKQHLEAKIAEGKTIIEKISKLKYEMARDHVMEPIPSDGEPHVQLYNTELEELARSSKNTWFTAPWLYAECYLYRLLRSYFVQTTHWRNYDPFHAQKLDVFAKSGPSIYGIATIMHELESERSALESDPTKLKVFFQEMIQMCLWGNATDLSLLTHMSLVDIENLQSVGKDMQAARKKFIMRDDQEKAWDHIQAVRDGRVDFVLDNAGFELFTDLVFADFLVTYTPNVSKVVFHPKLIPWFVSDVTPPDFKETIEFLLDPKSFLSDIASSQPQPSVEQQQHLRELAGRLRRYVSEGVFELSVPSETSLGGRHTTATPSTKESSLAQFWTAPVAYWDMATYDQELYEFLGNSDLVIFKGDLNYRKLTGDIQWPSWTPFEEALGPLAGSFPLLSLRTNKADVAVGLDEEVLAQTEEKDEKWRVNGKFALISFLGKRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZM6</accession>
    <name>A0ABQ8VZM6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="156" mass="16568" checksum="0183CC31090DDCA2" modified="2025-10-08" version="1">METHSADTEYLVRKGSNTGYRILSILTPPAYTVYVLARHGRPSFSINGLLRSTWIGGIAGAAGGAGIAFARYNYTNAEKVRAKRVQVAYDTGRIRAEDHATIGGVLLAVLTPAVFWNRARVANLILGGAGIGTGVGMIAHWTRSVTGDTPKPFVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0P7</accession>
    <name>A0ABQ8W0P7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_976828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1235"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1235"/>
            <end position="1280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1287" mass="146191" checksum="44892CF6F5B5AF16" modified="2025-10-08" version="1">MSDPLQCAPECKRGPFLSTQATNRHRGGCEAWNAYVAAQALKRGYDEVSGEDEDPAITRRKKQKRKKLEQAVARAESLSLPRSSIIATHAKASSSAVTLEQSKGPEIGTAEHLTPRALLSPEPNSPVYIGIDGQPDEPELAPEMTAAGRPIRSTRGHLPARYLDVLPQSAPAVGSSQVENEQQPAEQQNSPLTLPRIILIVRDKLKTQLNVFGLWREYPDRPSHDPDGEVGLEDLSNLPRSEEYRDDEHPEDARDDSPLNPTQTLLTGWQNNGNSTKSNSEMDGLTHILQRPDFDVKELKGYNAQAANKKITKADEDWEHNRFKDSFIETAIEIEVPSGSPQIPSKKFKIPQLLYRNPLSVIRAAFADRLASQFHFAPFKLFQEIDDDNGETISQRVQTNIYNSDVFLEEHKNLRRAPTDDKDCKREKVVAALMCWSDATQLANFGTAKLWPIYMLFGNLSKYIRASPNSGAVHHLAYIPTIPDSVKHEISKFNVNWKTQAKEIIAHCNRELYHAVWRFLLNDAFLHAYKYGIVIKCFDGVERRVYPRFFTYSADYPEKVLLATIRERGLCPCPRCLCPKEALDRMGLHQDMKMRDKLRVFLHDKVKLTREWIYEQGIKIQGSAVQRILKATSSVPTMNAFTGRLGLDFNLSRMLVVDLMHEFELGVWKALFSHLIRILYAVGQQYVEELNHRFRQMPTFGFDTIRTFANNASEMKKLAARDFEDLLQCAIPVFEGLLPGPVNSKLMTLLYRAAEWHALAKLRMHTEKTLDYMETLTYEFGKLMCQFQDLSNNSFQTYETDRETTARYRRKEKEAIAAGASQQNENSGRRRKFLNLLTYKWHALADYICSIRWFGPTDSFSTQLGELAHRVVKKLYSLGNKKKDPRQIGRRLRRLEWAKRAADRRGIHTKRRRQQRILNAGNAAELLAAHHHIGLSAKNKHNIGSFVKAHYDDPAAQVSFQFTRTLDILLNASNYCQNFYPKLQDHLLGRLMDRKFDGDTHESFTDADRNHIRLKGGSFISLKTCRINYTTYDVRRDQDTINPSNHADVMMLSGEDAAGAHPYWYARVLGIFRATTISSHPNASTTKSGPVEMEFLWVRWLGIDPGHQSGSRNARLPKVGFVPESDPFAFGFLDPAHVIRGCHLMPAFSDGRTSELLETEKPTVARKEGEKDDWAYFYVGIFVDRDMFMRYFPGGGVGHVANRKFFKQGEDSTNDNDISSISSDLGADELDVLDTEEISLEEMSEDGSDDGSDDDLGDEQGDSNDDDDDDLDVGGDDWQWDDGYGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1Z3</accession>
    <name>A0ABQ8W1Z3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">endo-polygalacturonase</fullName>
            <ecNumber evidence="2">3.2.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_191275</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045440199" description="endo-polygalacturonase" evidence="12">
        <location>
            <begin position="25"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4501190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="37747" checksum="603EA20440CC768B" modified="2025-10-08" version="1">MFHTDMQSLVTFVVLATTFSNTFASPTRTGTAKRSTCTVNSVSSASDLSDCTSVVITAFEVPAGDTVTISAASGASIEMTGSVSFAYTSATGPLWTFDTDDVTFTGKGYSFKGNGELYWDGEGTGGGVAKPHPFVKFKGYGSFTDFIIKDSPAQAISVGTTGTSSFTDILVDNLDGAELGHNTDGFDVSASDVTFSGNKVYNQDDCIAINSGSNIVFENNYCSGGHGISIGSISSDKTVSAVTISGNTVVESMYGMRIKVDSDATDASVSDITYSGNTISANDKYGLLISQSYSEDFGTPGTGSVISDINFTGSKTTVTTSGDYPRVGVDCGKCTGTWNWSELVASGGDSSDIVLAGGAKISGGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9ASN1</accession>
    <name>A0A9W9ASN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_302986</name>
        <name evidence="5" type="ORF">C8R41DRAFT_309113</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000007">
        <property type="protein sequence ID" value="KAJ4489546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9ASN1"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001423">
        <property type="entry name" value="Ras family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4489546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="190" mass="21673" checksum="D339D74CD6E1F93B" modified="2023-11-08" version="1">MDNWRVAVLGDGGVGKTALAVQFTLNCFTYDPTIEDAYRKQLIVDNRMCFVEVIDTAGQEEYATLRDQWVREGQGFILVYSIASRSTFERLDIFRQSMRRVKRGDPIFMLVGNKCDKTWEREVSKDEGQALARQFGCEFIETSAKTAQNVERLFTDLVRALRRTRNVEAGPPAGGPVRPPREKKTKCIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DD38</accession>
    <name>A0A9W9DD38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_442977</name>
        <name evidence="13" type="ORF">C8R41DRAFT_771803</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">TFIIA is a heterodimer composed of the large TOA1 and the small TOA2 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000063">
        <property type="protein sequence ID" value="KAJ4464009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DD38"/>
    <dbReference type="OrthoDB" id="586585at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000003">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="10">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="11">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00063181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4464009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4479899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="114" mass="12768" checksum="7BCBB827D58C2AAB" modified="2023-11-08" version="1">MASAYYEFYRGSSIGMALTDSLDELITSGSITPQLAMKVLQQFDKSLADTMVKQVKNKTTLKGHLHTYRLCDDVWTFIVKDASFKMESNELVNAPKIKIIACKNGEAIESGNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DQS7</accession>
    <name>A0A9W9DQS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">37S ribosomal protein mrp10, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8J55DRAFT_428589</name>
        <name evidence="2" type="ORF">C8R41DRAFT_748245</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000015">
        <property type="protein sequence ID" value="KAJ4480508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DQS7"/>
    <dbReference type="OrthoDB" id="2210at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017264">
        <property type="entry name" value="Ribosomal_mS37_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9149" checksum="CC3B891732B85E3E" modified="2023-11-08" version="1">MAIHIKNLKVRPKKNAINVMCAPQLTSLLGCWAASNDLHSINACRDAAQDLFHCMKTTPMPKKMHRPTINYHLARLGKKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DVV6</accession>
    <name>A0A9W9DVV6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_508518</name>
        <name evidence="6" type="ORF">C8R41DRAFT_810629</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000010">
        <property type="protein sequence ID" value="KAJ4486743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DVV6"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4486743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="130" mass="14639" checksum="7079CE869B77F74C" modified="2023-11-08" version="1">MVRISVLNDCLNNIVNAERRGKRQVLVRPSSKVVVKFLSVMQRHGYIGEFEIIDDHRAGKIVIQLNGRLNKTGVISPRFNVQVTQIESWVNLLLPSRGFGIIILTTSSGILDHEEARRKNVGGKILGYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWN2</accession>
    <name>A0ABQ8UWN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Delta 12-fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_132838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="86"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="435" mass="48461" checksum="8910E6E44595E318" modified="2025-10-08" version="1">MGAQREIVVEQEPVVIPDFSVKDLLGVIPAHCHKRSAFRSSLYIVMDVAVITAVYNIATFVDSFVNPESLSLPHPLLFPLARFAIWALYGFWTGLFATGLWVVAHECGHQAFSESKFVNNAVGWVLHSALGVPYHSWRITHGQHHASTGHMTKDQVFVPPTRSQWGLKPFNPEQENLLGSRVSEEVSKELWDALGDSPIGAMIGSATYLLGGWPAYLILNASGQKYPKGSNHFNPSAVMFKDREWSQIIMSDVGIILWIAGVIASISVYGFTNVFVLYLVPYLWVNHWLVLITFLQHTDPLLPHYRAREHTFPRGALATLDRSLLGDLGSFMGWIGALATHGISETHICHHVASKIPHYHAWEAGEHLKRKLEAAGMRTEGAPAGWAEVYRVFKECKFVEDEGDIVFFKDARGLAKARPAYHSDSPSDSGIELEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXP4</accession>
    <name>A0ABQ8UXP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_804018</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000131">
        <property type="protein sequence ID" value="KAJ4465094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="14" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="571"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="511"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4465094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="990" mass="108182" checksum="62E9A8F7177894DF" modified="2025-10-08" version="1">MSSPPALDFPSSEADMNEDGDQGAAPTNNLPLFLAGTPSTNAGTPARTRGNQSIAGSSPLRNITARRAVGLSTPKQRPLFAPGSSSPIAFPSSSPSKTPRRRVNFTSDPPIANQDSEPLDFPSSPTASAPINRRGDIHSSLSITPTSHRRVRPPRSTHSNADPLTSDGIQLDLPPSSFAPLLSAANDPVSEEPDEIRAIWGTTVNINQTIQLFTDFLKNFKTKYRIAYNRENRLPTSALATPEEGEVLVYEGYLRRMRQTGETNLNLDVRNLLAYPPTKKLHTQVIKYPQEVIPTFDQALKDVMIDLAEQDQAEGLEGMQDAAGDAEISDILSKVYKVRPLGVTPINMRELNPSDTDKLVCIKGLVIRATPVIPDMKVAFFRCLTCSHTIQVEISRGRISEPARCPRDVCASVGTMSLIHNRSEFADRQVVRVQETPDAVPDGQTPHTVSLSVYDELVDVSKPGDRILVTGIFRSTPVRVNPRQRSLKSLFKTFVDVVHIKLGTDKGLGFDRSTRPMGGDKIPGVGGVGDGLDGDNPDADTLDDVPSVEGGSSRRALHQDHLRELSQQPDIYERLARSLAPSIWEMDDVKKGILLQLFGGTNKSISRGGGGGGPRYRGDINVLLVGDPGTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDPDSKQLVLESGALVLSDGGVCCIDEFDKMSDATRSVLHEVMEQQTVSVAKAGIITTLNARTSILAAANPVGSKYDVDLPITRNIDLPPTLISRFDLLYLVLDQVDENLDRRLAQHLVGLYLEDTPDNSGSDILPIHELAAYIDYARSRIHPIITEAAGKELVAAYVEMRNMGTDPRTSEKRITATTRQLESMIRLSEGHARMRFSEFVENQDVKEAVRLMREAIRTSAMDPRTGKIDMGMLNTGTGQGQLKLREDMRRELLKIINATGGTRGVKWTDVVKSLSAQSSIKIDSAEFTEVVKGLENEGLVKIVGERDKRMIRKMDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXT5</accession>
    <name>A0ABQ8UXT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_898810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000165">
        <property type="protein sequence ID" value="KAJ4463450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="9">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4463450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="314" mass="36192" checksum="9509DA8F581F17B9" modified="2025-10-08" version="1">MTEWDHGKENKRIEIYTDGSCTGNGTDEAIAGAGIYVPNNNALKFEDRGFLGVKNVKEIKVTIARLHERKAPTNLRWVKGHSGIEGNEKADQLAKEGSEKSHTDTINMTIPPPLQISGMKLNKLMQATAYKAIQHRKMNTRAYQNALNRKATKVNIGRAKASVQEIGSNHPTDTNLWKSIRNKDFERKTRTFLWMVYHNAYKNGEYWDTIPGYEIRANCSECRCNCPGQDLIWRLGQELWKNKRSAWVKPHFGIILGCGLANFKNDDNKPLSGDSRLYRILISESTYLIWKLRCERNEIIRRWRKTLENRIQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY06</accession>
    <name>A0ABQ8UY06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">60Kd inner membrane protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_859003</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="12">
        <location>
            <begin position="180"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4464957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="442" mass="48546" checksum="2F82FE27294C2D90" modified="2025-10-08" version="1">MSSLVGLRIQLPARRFNALINVSFHQPSRTRSFSHLVYSHNTRSRNLPYLNTATTLSRSFSLWPFSRSLPSAPLPGSEAAVSAISGSSNIPTHKEAILSEPVSSELSKSLPEGVDLVPPVELLSPDVVDATINVANASNSLVPPALQLGDLASLDLISYTPAGLIRWSFELINVGTGLSWFWTIILGTLFWRLALFPVVVKTLQFSSRMHLIQPQTQAIMQQTLQARQKGDMLAMQKLQKDQVALYKSVGLSPLQGLVGPVFQLPVALGMFIGLKKMCELPVPQLTVSGMDWLPDLTAVDPTGIMAPAFAVTLFWQMTVSARDMNVQAQPGMAHIMNLMRFPGAPLFSFFMTTLPSGLVLSIIVAAIATGLQSLVFRIPAVRSFLGILPPPQVEGRQGLPSFKETFAYVINWWKNKWTEAKNDAQNRAEQQRLKGGPPRRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZQ1</accession>
    <name>A0ABQ8UZQ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_855566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="565" mass="62924" checksum="A178BB9BEC2883D0" modified="2025-10-08" version="1">MDENEQTKRKKPPACDYCKARRVICHAQSEGPCPRCVEKGVPCTTTALAARRRRRTKAEMQEERLKKANKTADSTLRTAGLETSQPNEGPTRHIEAPHFIPPSLSLSAELVAELIQIFHILPQSLHPIIPLDELEASLRLASWSLSSLPPQLRVLAQCIVTLASFFSTNAAIVGRGGCGPEVTSIALSKAPLKEPVVPDLREYGVRRKPVCYQLWTEALSLAHQQGITAHVSRENAACCWLLDFLECRFSGEGVSTYASAYNSHLRCLAETNDSAIPGDAEAASPGTSVLYRAYMMHDAVYAITSRRSIPFSHQDELLISGPCTTTLEQLLQEFSSDVSNKQLFLSMNAFASHTIRLARESSERLSGVYARRRTLDEVFLASHFASLDLMHSILLAERDRALWVVDNSTESHFIRSCAYALHISWGCLVLNLYDLLLDRVNNNLCDFDLGFTVHSAVPSATEYDPREWARLHFSRVRQMALRVAVGISEALKDVPCISRVTHLHFEELEKWAKLLLGESGTVVINRSDRSRALQCYRDALKIAGFSWANRSAGLVEIIDEHLAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZV4</accession>
    <name>A0ABQ8UZV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_50727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000107">
        <property type="protein sequence ID" value="KAJ4467505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCUN1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="184" mass="21100" checksum="FAC2429CC921DCFD" modified="2025-10-08" version="1">MDGAMPLILAWQLDAKEMGTFTKDEWLKGTAKLRISTLPSLVIALSELDDLLISDKSPAKSNPKTDPYDRGTYLNYAKNVKDAYQKLYIFCFSLAKPEQSRNIDMETSTALWSVILAPKYPIMQEVLEFIAEKETVYKATNKDLWTMMLEFCETVKVDLQDYESDGAWPTLLDDFVMWKKARST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0N3</accession>
    <name>A0ABQ8V0N3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_984707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="33796" checksum="C83CBE74046FF391" modified="2025-10-08" version="1">MDVRQSKDTGWRALSSTESTPSSIDQLLGVLSQLDSALKISVDRNAFDKLNHIYADEQANVETALHNHQMTHRNTIVVKPKFDTFGVPHSMKDLDFWTELDGTPYHSSDGTVVKFWASFTPVAIINVGASPIGSTVLHDRAPARLFLGYTYIREGEGELDQWTRQDGSHRSMEGRVGYLKFRKQFYELEIEIDEEAFSKLNYIFIDNHVVTKVEDEIRSHQMNLESTIVVQPQKDKLNGMDTMKNLEFETEPGFHRSQDGTLLKFYVSSVTPVKKATSKKVADWRAWKGGILNLPSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0N9</accession>
    <name>A0ABQ8V0N9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_906042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="804" mass="89158" checksum="FDF60D516080370C" modified="2025-10-08" version="1">MSLPVSLDPSLLGSCRNSPPKCQAFCGIFCTEDGLLDSVSASTKCLICGCFAASHIHPPDHKTQTTSTSMDPPPLSSSKPFPKPFPSGSATANSIFGARSGLKTTAQQFSASPFRDHIKERETRRESTNVNATSDPELGDKRRFNPAEADRKAQFDNITGRPKKKKKADLPKSTKSSAKISESLPKPVVFHVVLYGKPSLVSRGEATRPSSTEFQALWSSRRIRPISLPPHAAHFEICTAIELAFADLLPATVQPSDVQFCILQVQKVGRGQSALLKLLEKDTFNVDDLRMASVSAKPKDIPSTVVKTCFYITLPSGSSDIDPVDSENSTKSTSGKPRKKSKKSDDYSSDDSIDFDEENGANNMPKSLLLRPLDFDILKRMLVNMAGPSDSDHCDWWTTSSEHHFIYSGYTDTTKMLTNWFQRLAATSNGKSASPDLIYQEVFRRIMDIISVNVIGNATDLVKLHRSIPVWTTFDDDEFTFIFSLGPSGMDLIVTCLETVFSEGEAAGPNFVRKFASNYCDIYQNLRELPTALLSLVKRFRERTFRGLWDPKNGYSQLIHVLDQQGQNLPNGSVSSIFYHEMSHINLTSLSSADIRIGLEKVFGSITDSTKIHPSALCKGQYGLHGFYSRFAGDILDWMNMNRDGNDYKHIFNDFATLCGALADRIKTHFPSTQRASTSGHTSGPSCSSPLRSSFTPTSGSAPNQPSATVSSSSTSSSSRVAAAQAFAERVKDFKWSEFVQALLQDYPHPELSKRLYFTDIKKLNKIQQYRKLYLIYHPDRNRIPLEWNQIANILTQTIGYARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0P6</accession>
    <name>A0ABQ8V0P6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32341" checksum="15685A7686D7A7A6" modified="2025-10-08" version="1">MFDTYHLILLQHFEANTGVPATPRSKNETIEVEVGSETAEVDLEDGTCHIQPSGVTGVSNFLPQNAPPEAQIHGDEGPYLESKPEYVDRLSDALDLQNDTKGRYIFIWISMSVLLMRQTRTSKPVAKLEDETTGRTIRGQSEFLHNSIGTTMGKPMQPLQDGKRAFENVGSESPHLIAFKSFVLSEFLFRAGTLSYLLFVIKRLRKIWTMFQNQSAIAVGHLVVSVGLFIVIQYWGTKPVEIQAVGQRSRYSRIIVDATVLAGAFICTSVVWQIVSVIGGSVVKILRMYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0R6</accession>
    <name>A0ABQ8V0R6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_860055</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04043">
        <property type="entry name" value="C2_Munc13_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052811">
        <property type="entry name" value="Glucose_resp_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010439">
        <property type="entry name" value="MUN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014770">
        <property type="entry name" value="Munc13_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263">
        <property type="entry name" value="ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263:SF1">
        <property type="entry name" value="C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06292">
        <property type="entry name" value="MUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51258">
        <property type="entry name" value="MHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD1" evidence="3">
        <location>
            <begin position="674"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="865"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="domain" description="MHD2" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1299"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1300"/>
            <end position="1312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4464403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1335" mass="151434" checksum="E096E77BE73C61D1" modified="2025-10-08" version="1">MSRRSLGSFAHDKRLSKYRVTDDELFNYVLRVALLSYLMIPKPTTTAEIKSSDSKDREHSSRLAALSNFSIGDMIKDLRDGPNSKSVKFPDKLIKVLEQKLQDIAMGKDPAYSDQLVRRTMGKFYGQFMVDSFKRQMKENRKIEELILMFATHATGVLKKEPTLTGDSWKFELNNHIALFVKLLRESLRGLNHVSPELLGRLDMYTAKLGPAQSSDSGYESSSTSRDRDSIASLTISGHVSDMPLVKTVAALFRLSESSVQKEVDQLRTLCTEKAALADLKTCLKNINAGAPFPGRREDFESEDAWQHWKTLETTQLQQMMVAMVQFNPELAKSTPSDVLPSVGTSSSSTRPGSVYSQTQSSSRHGSISSRLSLHGLGGDFVDITAPEDGDEDGIEVGHHFTYIPPNPKRFYKRLLELCLIADLELMLSPEVDDNDEVSLGILSALHIDLLNECAIRWRIGHSYRASCFLDLVKQFYERNDVPLECIPEALQNVVRVMHDMDLDKWPLADVDYVCNIYGGLFNIFLSSLYHSMDSIPHLKPSEIEPYLTILEHVRDSGFLDRFNVDVNARVSDVQTRVRQVALESFSTKLHELQSTPGVNRALPLLLMTDELEKSTKALDKRFPEPILGKIDLVSLVVEVQIPLFVTEVQSSQKRLFESSMNGPTPDIPIQDIFALYRRTKTLISMLAAFAPEQRVDFNLTGFFEPYVLQWLTNTDNKTSNWVEAAIAADKFQAEGTEGHSSSIVDLFDSLRSPIDFLQDLEWEDEYQNARFFTSLSKTIAKAVEQYCRTVETKFLAEMFPRPNDYLQPQKSSAWLEKARQLAIQGEKKIEPFNFQPESCVKLNNVEAARKLLDNMYNQIEVDKLAGVISDSAPPVPEKVERERFLFSVKIVLAEGLVSGEASLTNKLDTFVTLSDEAGNRLAKTRTIYETAAPRWEETFDISVDKPLWLMVSVRDRALVGKHDTLGRAYLCLDPRRFGDLMTHDLWMDLDSSGRVLVRISMEGEKDDIQFYFGRAFRFLKRAESDMLRIFIDKMSPFIRQCLSRSVVKTLLKANSLGLDVNKALGNVTALYRSALGSSAGEVQIPLPSGEKPRVRPEELSDVEIEQAILPLFDYFDANLQTLNTYLSETAKEKVMTRVWKEILTVLEGLLVPPLSEVSSDMKPLSDKEVDIVFKWLKFLRDYFYAGGEGPVPLEVLQNQKYRDVVSIRLYYDWSTDELMEECVRMMQQSLRSSAGTIMKRAKSVYQQRNLGTIKERKKEKQQEKEITNGQTIMQILRMRPGTSDFIAQQLQILTQLQQDQEKRAKQAEARKVSRPNNSVKKQNADLPSVPPLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V155</accession>
    <name>A0ABQ8V155_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein Het-C-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_36461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF7">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046733406" evidence="2">
        <location>
            <begin position="24"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="735" mass="81720" checksum="C6E0701E063F90D0" modified="2025-10-08" version="1">MPKASNFLLLTAIFCLLPSNVRAFGAGDIPDFAYLNDKAFRHGDIENILEQVLKNAALAAGGTSLFGFAKKAFQNVSGGSKFDKGDIKKIYFGNWLRDYSQAMDIAGLSKLTAETLVLVVSVLGFMTFGFATEEFEVTADRLGVYLPVEHIDNPKGYAEKEGDARSFHPKLRPPVDPRELKIDPRNGMKNYMATEDQGWDSSTAHIRRTFRACIEHGRRAGGREGSDLWEAYRFLGTGLHTMEDLLAHSNWCEISLRKMGYSEVFCHVGENTDIDTPNGRAPPLVTGTFGSADFLHSLLGEATDHLSQASVTSLSQKMTDASNESNASGNIENLRKIFSKLPIGGSDDKMNEAEELQQESKAYNFNPDDIAPPDVQKRLLEMLAWRDGVFRWITAKIEMIPGLSSLIDELMNALNAYVYTVIAPWLTPILTQATSVLGEGSKAVIDTDDQYEVFDNPYASDPSHSLLSKDHFGLILNEPAGKVAQIVVVYSTELIVKAWADNSDPDEVVDQILKAFHHPYFADGHSSIQHKMFEEMERWVGELSPDETSQTIQALSKDSVRNGKNKRLTEESVEVEAGYGKPSTFQSYTETSSYMQGGRSDTSYDGKESYGGQYQQQSQFNTEYNTDSRGLRHEYNSEDNNQQYSDVDNKQGTYGREDAYDLGHSQQYSSSIGYAGSQHYEGYDPNQSRQNPHGSGLAFSNYGRPTGSSYGYNREQQDPYGSDEYRSLPRHGSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1K6</accession>
    <name>A0ABQ8V1K6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-tyrosine phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_912384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF10">
        <property type="entry name" value="PROTEIN PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="1">
        <location>
            <begin position="162"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="33110" checksum="D59EBA2BF45215E5" modified="2025-10-08" version="1">MTETITNPPFIGINNFRDVGRVINACTSRHDFVEGCKLTRMKEGMLLRSGRLDEATAEDTQLMVDKYGLKTVIDLRTKTEHSRSRDFEMQCERRWDTVKINFISRKFELNLLKQLRWWQALWFIILMLFQQRMAAIRIIGQNVMSPRGLAALSKDSLRFCQDEILQALEVYISPQVYPVLVHCTQGKDRSGLIIMLILFVLHIPLDLIKTDYVLSNQGLERVRASMMVEVLEIGMDEKYTQAPEKVVDEVWSFLEDGGGVEVYLDEIGFGESKRQKLRELLLEYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1U5</accession>
    <name>A0ABQ8V1U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ubiquitin elongating factor core-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_110288</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000131">
        <property type="protein sequence ID" value="KAJ4465100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16657">
        <property type="entry name" value="RING-Ubox_UBE4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="10">
        <location>
            <begin position="1012"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4465100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1102" mass="124610" checksum="A682D37A05A95E66" modified="2025-10-08" version="1">MSDATPNEHTPQDDAERIRLKRLAKLQTSASGFAAPSGSSTPAIGTSRPSSPKPPLPKVISKPSPATKKILEPTPTPLEPPIRKKAPLHLDLDIWEDEMITGVLKVTLDKSVAEQSSYDIVWLKPLADEMKSEAVVQSLRLNIDLIDRLLIARLEIDPKAMTDDLDFLPVLASLPPQQTIFEYLVGAWKRLNMFRTSLIKKGYTPAETQTALTRLDKLRDLVISYSGLTLQEPEMFPQPSGRLLGPPELVTPLLSLSTLSTPLYSSSTASANTLSPTDVELFLQDLARRFEPDNEIDEVLGDVVRQLLFHESLFRPEGLGGAVATWRGVVGGLEALVSVKSIAVMITRMPEWIPANATAANFEKLSLMGPLCRLSVFAREWPAIAQSYFSEPEKRSPQDLESSYASLRGTLKSLQGTLFHIFNTLVRAAPKSREAVLQYFNKIVSLNVKRAGLQVDPDTVASDSFMVNIQSVLYRFAEPFMDASYTKIDRIDPLYFAHSDRIDVTEETRIKATAQEASQWAEENRLSGGPAPNFISDIFYLAVATSHYGYQKTISSYIELDKHMEDIERHLSFLNGDGSWMGTPLQARIQASINNINNEKAKVQSAQYAYEAQLKDPELVFRSIGFTIFLSVWLIRQADPKKTHPNPLAELPLSKDVPMSFRVLPEYIVEDIVDYFHFATRHAPDKFELAGKTELLTFILTFLSSTWYIKNPFLKSKINDVLFLSIWGYGRESTGILGGLLNTHPLALKHLMSMLMHFYIEVEQTGASSQFYDKFNARRNISYVLKVVWNNPTHREALNREAENVDKFIRFINLMINDVTYLMDESLSELTQIHDIQTEMDNKEEWNSKPLEYRREREGTLRQLERHASSYTTLGRSTVELLKLFTAETKKPFMMPEIVDKLAAMLDYNLEALVGPRMQNLKVRQPEKLRFDPKALLSDVLQIFLNLSDQPEFMKAIAGDGRSYSKGLFEQAERIMFRRSLKSGTDLEKWRLLITKVEEAKETLEAEDDLGDIPDEFLDPLMFSIMRDPVILPTSRTTIDRSTIKSHLLSDTTDPFNRMPLAIEDVVSNTELKSRIDAFLIERKQRNKAAGSGLEDSMNVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2F4</accession>
    <name>A0ABQ8V2F4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="266"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="372"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="427" mass="50554" checksum="1FE5CD31071CBD67" modified="2025-10-08" version="1">MRRVPLSRLEDTRSNGYCAVQFTHVLKQFLVQYRYPNIPINQIDKWARFVVLPFSLLPVWHKLKFVNTELFSKKTLDSFSAHPSSSKRSNKSIKPSRFNTVLVRLKQGNDWTKDMRVGRVRVIFSLPSDKLDTLVPSDIPPPQHLTYIEWFTKFVAHPEPYSGLYRVRRDVGADGLYTASIIALDSIVCSAHLFPQWGGSVPPEWTNIPIRVSTLPNRRLKCSDFDMSTFTKRKPEVPYIFKREPYFKTHWTMLKCPACFTSRMALDNEALKVIRLEAQMKRLQEDCATKEFDLRQTQKAIEDFKMRMQDWEQQDQDLKEHEIALKERELSLYQREVLLWESKADLARRERQDADALYERWKRTRDYHITAIESEKRMRAEIKDERKRLEEYEKEVVRREKKNAKKLEEFNDLHSLEAHRIIAAATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2N8</accession>
    <name>A0ABQ8V2N8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_924722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="265" mass="29591" checksum="FE0419E372F3D2F2" modified="2025-10-08" version="1">MSISQDPSTRAITISQQGYFTRMLQHFGLQDVQPKKTPLPVGIQLEQSPETLPDDEHMFMENKPFRELLRSLMWGSTCTRADIACTRLLLGHSTTTPDTTWAHAKRSGAITITITTTILQSNEQTNDVQGVWSGNLNLLETRNERYPHTGGEEEEEVPKHITVDMRYTLLTDLLLILIADSVYDSRSRSLLSLSWWDIVVFEGRIVGAGEGVGESGTDATDGGLQKSESAVADQVRRLRNRRIALLELTRPGEGLVMGCWHPSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2V5</accession>
    <name>A0ABQ8V2V5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_804604</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="9">
        <location>
            <begin position="245"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="297"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="373"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="512"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="553"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4463905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="576" mass="62377" checksum="8884B97B77A914DF" modified="2025-10-08" version="1">MFLPKTPSRHRTRSDVGKTPKTPLTPSVLSGLNNISLGGFPTKKRTGKTHAKASSSGPFDTTNPFIQPSTSRSRPNSRPASPVKFATGAIPISEDLKGQAGGGLIRKGGVELSRLDVVSRDYIPPKPELKRSRSTPAANRDTRDRFITSRDTENDVAATLEQMHLNPKSASPGHTARLVAATGVPLNRRILGYHEPPPAASSDTSLAQQREFAKPLYARPGTLPTSTGSSTNKSRRIPTQPERVLDAPGMVDDFYLNLISWSCQNTVAVALEASTYIWHADTGSVNQIGEAPEGSYVSSVDFSNDGMFLGIGIGQGDVELWDVETGQKLRTMSGHQAQIATLSWNQHILTSGCGDGSIWHHDVRIPRHKVMELLGHSGEICGLKWRSDGELLASGGNDNVVNIWDGRLGDVGEGARGSAKWTKRNHTAAVKGLAWCPWQANLLASGGGTNDATINVWNSTTGARLHTQKTPSQITSILWAPHKKEILTTHGYPTNSIMLHAYPSMDRVAEIRDAHDSRVLFSCLSPAGDVVCTGASDENLKFWRIWDVVGEGSGKKRKENEERRVNSTSSGQLSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3P7</accession>
    <name>A0ABQ8V3P7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_48320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051767">
        <property type="entry name" value="Nucleoporin_NUP42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527">
        <property type="entry name" value="NUCLEOPORIN-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="228"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4467781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="490" mass="50839" checksum="697F89213D79817A" modified="2025-10-08" version="1">MVVCSYFLRGQCRFGDKCRNEHPQSGNQTWVNSASGSDTGVKNSVGLFSSESLSSDITLGREKPLWPLSSYGPAKYEPVIVVGLDACPEELRVKAWEAKVQNNLNGYIQYEATQISQADNAFNNARNNIQTLYTQAVKQSSVVGSTTGTSSSAFPSSSSSPFASSSSSNGAFGSQSAFGPSSVSTPSIFGASANSNSVFGTSNSAPALATGSVNNGAFSSLMNKNPPTSAFSTPSTTATTSAFGQPSAFGANNNSSPFGKPPTSVFGSSTFGQPSSTAFGGTPSTTNTSSVFGAPSTTTTSAFGQSSTFGSSPAASTTSAFSAPATATTSAFGQTSTPTSSLIKPAISGGAFAAFANSGPSAFGSGAPSGSGSGGGFAAFANSQPSTFSGTSSTNTSGSAFVPHHRQPQHLLSALWHLLHLPLRLVLLASLRQQHRRRHLGNLHHRRQYLDNQLPLHQIRLPSLGDHRQTLRLHSLKHLHLLNHHRLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4G8</accession>
    <name>A0ABQ8V4G8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="22526" checksum="CCB51DFB0FFCA11A" modified="2025-10-08" version="1">MASTSSQTQAAASTTLLPTSLMEAQGDYSPLRSILRIPRISMELLPFQPFRILVLCPNGHADVTKWDEDSIETDPMELYHLFEDAAPYLLMQQWGIPPNIGLLLRKRTDAYGSSEDLDVFASLRGKGSPGTSKAVSPPKVSDIVSSPPATKAQTVPPRALRRNREIESLKVDASSFRGRHYLEPLHLPRFRGKKEPKSKTTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4P4</accession>
    <name>A0ABQ8V4P4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_563312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046379743" evidence="1">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="168" mass="18412" checksum="AF288E838F1C1108" modified="2025-10-08" version="1">MERKITMHFPVFLFLVLCAVSASTVVYAMPFQANSESTPSPHSQIARANSRPPVTAIVNFLDHNGGDFIPFAGDNGFVVTSGVEAQAHGIMPLKVYNRVRHAVEFLVPSADRGRGLVLGFENYFVPSAKGHEDDDIRITLHGIEQYPNGCWLDVDKKGKIVPGMFGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4W0</accession>
    <name>A0ABQ8V4W0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-1,3-glucan synthase</fullName>
            <ecNumber evidence="2">2.4.1.183</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_983662</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19749"/>
            <dbReference type="Rhea" id="RHEA-COMP:11150"/>
            <dbReference type="Rhea" id="RHEA-COMP:11151"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28100"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.183" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11323">
        <property type="entry name" value="AmyAc_AGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058659">
        <property type="entry name" value="Mok11-13/Ags1-like_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058656">
        <property type="entry name" value="Mok11-13/Ags1-like_GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058657">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058658">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26122">
        <property type="entry name" value="CBM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26108">
        <property type="entry name" value="GH_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26114">
        <property type="entry name" value="Ig_2_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26111">
        <property type="entry name" value="Ig_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047088140" description="alpha-1,3-glucan synthase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="2348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1067"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1926"/>
            <end position="1948"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1960"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1984"/>
            <end position="2004"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2016"/>
            <end position="2038"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2087"/>
            <end position="2108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2168"/>
            <end position="2190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2240"/>
            <end position="2260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2272"/>
            <end position="2290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2321"/>
            <end position="2340"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="11">
        <location>
            <begin position="70"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1640"/>
            <end position="1724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1692"/>
            <end position="1706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4474520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2348" mass="262360" checksum="E2648F8E6CE19A7D" modified="2025-10-08" version="1">MRFNSAFFYLFPLLTCIRTLVSASPYREDLVNYNLNTNKDATDPTQYSTTRQNTTYTSSPGNWRALPVYTILLDKFADGDPSNNDYFGTMFENDWRETQLRFGGDLKGLVARLDYLQGMGVKVIFISGTPFLNMLWQADSYSPLDFTVLDPHWGTWDDWVDTIAEIHARGMYLMADFTVGTMSDLIGFDGYVNTTAPFDLNEYNGVWKHPDYIPWNFTEYKDFQISNTRNDSCQTPKFWLDDGTIVTVDTNGCLESDFDQYGDMEAFGVHPDWQRQLSKFASVQDRLREWKPSVMDKLTAFSCLAITALDIDAIRIDKATQVTVDALATWASSTRNCANKLGKNNFFIPGEVTGGNTFGSLYIGRGRTPTMLPPGFLAAANVTSNMPEYFLRDAPLNALDGVAFHYSIYRSLTRFLGMDGNLQVAYDVDTNFVTAWNQIFVTNDFVNSQSGLLDPRHMFGTSNFDVFRWPSLENGTQRSALATFMTSLVMPGMVLYFYGEEQNIYMYDTGASNYLYGRQAMPGTQAWKRHGCYKLGSTQYFNMPLNKGALGCYDEWNGRDHFDPTTDSRRLFGQFNHLRSVYGSLQDGFNLVERGNWTYYIERPGSNGSATEMGLWSISRSAISGVQTLGGTYQDQVWLLFTNENTTKTWSYDCKGDLWISSPYTSGTTVRNLFAPYETYTLEDSLSSYNNDNQSVWYGCLSSVTMAPYGFKALVPANEWTAPPPALTAFNPGHDARILASPGDANATTVDVSLEFNTEMDCNSVTNSISMNMSSYSGAPTPSITNVNCGALTNPATGNVPGVSQTQWVWNATLANFPDGILTLTVNNPSSSGGNGTGSTDHLMLRKGTSGNVMVFPDNDYNSSALSYSDGTYIFSHTAYGADQFRYSWNYGQNWTNWTNWQDTTTIDTSLFDGTSQFWDGDHIMVQYWSQAALSTAAVVHADYGYSGYPRRVPQFLARGPFNDWGFDKGLANQMTQNSEGKWELEIMAQWPTYVQLNVFGFDSFYYGDTDGDGVLDRLPPNTAAPNYLNMSAPPSPHLAWSLIVDDATMTWSLSPRGQSSVGATMYALLLSIPLVTGSLAVLIFMWSFYGIKYNQYGVKVKSSNSNYFPIFSAFSNNRSNTDFKDGGAVSEKLFGHKHNNEIIGWPEDKNKRRKVLIATLEYEIIDWKLKVKIGGLGVMSSLMGKAMTDVDLVWVVPKVKDLEYPPGEPAQPIEVIIFGEPYLIEVETHILDNITYVILDSPVFRAQTKADPYPARMDDLSSAIFYSTWNQAIAATVRRFPLIDIYHINDYHGALAPIYLLPKVLPICLSLHNAEFQGLWPLRTKEEMKEVCSAFNISKEHCTKYVQFGNTFNLLHAAASFISTHQKSVGVAGVSDKYGKRSWARYPALWTLKHVDSLPNPDPTDIAALDEKPVDAHDVQIDQVSEAARPEMKRQAQVWAGIKQDPDSDLFVFVGRWSKQKGVDLIADVLPSLLEKRPSIQVIAVGPVIDLYGRFAAEKLARLMEIYPDRVYSKPEFTALPPYLFSGADFALIPSRDEPFGLVAVEFGRKGALGVGSRLGGLGLMPGWWFPVESTSTAHMLSQLTKTVKLALKSTEEERAILRARSALQRFPVVEWRQRTEDFHKRSITVSRNLSGANAWRESDCNSEGARPMVDTDDWDPVSQSYPSQPEWDNRSSMTSASLASPVALNSPGSPGRWSQDTLTPNAAPRLLQPDGYRSSYSTENGEVDYFSHSNASPEHNQSYGDFLEKANRVIGRDHRYAPDPFLDGGVTPSRPFGLHSRISSVESISSIVDEKSNSPLNKAIASFTDSDGGVAADFIQKLQALNAKNSEHELSIEKYLMKSEEAFFGKVKKDKLSSAASIRSSQRDSVFGIPAPSIYSRPESPKSAFSPMYDEGTVHSNGPPSDSVPMTGLQIALAREIKGWPLYTIIIALGQMISATSFQITLLTGRNWEDNLQLYVLGGVFLAASAVWYPLFRLKPSIYVLSTPWLFFGLAFLMIGLPSVSSAFHPAHRIIANIATWSYAVGSAAAFLFFGLNFGEEAGAATEVWTFRACIVQGSQQVWVAALWYWGNSLNGQTDDYIPPWWIALIVWPLAVLSFIFFYLMLFGLPEYYRQTPPKVPHFLKTLFRRKLVLWFLASEILRDYWLSGPYGRNWGFLWEVNVPKWQILLLVLTFFVGVWAAMLFVLTHFSKTHTWLLPVFAVGLGAPRWCQMLWGTSSLALYIPWAGHSGPYLGLSLWLWLGVLDAVQGVGLGMILLQTLSRLHVCATLAFSQIIGSVCVMIARATAPNAIGPGNVFPDAAKWDFSEGLKGSPMAEPMFWLALFCQLVIVVGYFWFYRKEQLARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V569</accession>
    <name>A0ABQ8V569_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_778214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30140" checksum="835661304174CCA2" modified="2025-10-08" version="1" fragment="single">RLNAQHNIITNAFGGKLSVAPINLATGDRVLESAAGSGIWALEFFETNRADGITLDIECIDISSEQFPTTHPPEIKFSVNSVVNLPNHEWTERFSFAHQRLLVSAMNDSLWHLAVAELFRVVKPGAWVELVEIEAQGFGSWSVGPHSTKLAFLINTMYDKRGVIGDLSVYLPLILKEAGFVDIKCEARHAPIGGEADAAAPHKFTQVKGFDSEMWRELWMGMKEPVIEAGGYGIVKTVEEYDSLVQGAAAEWKTSKEAYTTFYAILARKPSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5E6</accession>
    <name>A0ABQ8V5E6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_848863</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="417"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="417"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="43"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4473473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="471" mass="52488" checksum="DF654CF383CB7AD9" modified="2025-10-08" version="1">MDSFPDTRPSSPGRHLRIQGYLENLNGEIRTLLADNSLYTDIINKLKSDLNVYQRAFSDVNAELDRYKTQMLETEKQKEDLEARLKGHRVVTLIDGDGAIFSKELIVQGQAGGLIAAQKISDSLIQHLSERYGSHQYQLWVYVFLNKKGLMETLGRLGSPQLKNNFEDFVTGFNQAAERFSMLDVGNAKEAADAKIKCHLEDDIRLPQTFKVIFAGCHDNGYVTNLRSQITAGYKNKLILLKSYAEMASGIAEMDLPILTIPDLFVAQKLGVTEVAASRFPSYSNATIVGETKETNKQIPANPQIVSPPTSYSSVTAVPYKRDSTPDLDFSEGSTSGESDYDDDLPHNAVVAAMASPNSSSQSFSNSRYINPNIPLWKHKPPPCTLFYLASCKHGSTCKYSHDYYLEAEHYEVMRENAKKQPCPAANRGEVCTWGEECCYGHYCSALSKCHFLKQGRCKFSGANMHKNPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5E7</accession>
    <name>A0ABQ8V5E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_777431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="139" mass="15759" checksum="6D2AA79D9A70E8A0" modified="2025-10-08" version="1" fragment="single">AFIRPGVTADRLRAFEENREANGPKVRNTMIDKNGATTNDLKESSWNQELLLVLVKLAEQIVDECKDARFPASIDWIGLFSERLYRVYLAVIKGKPRIKQGELESPAQIEARMLSTHIERNKNNGETGFRHAVCVFSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5U6</accession>
    <name>A0ABQ8V5U6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_847634</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="170"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4474780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="328" mass="36656" checksum="275B13B0BD5EB2D2" modified="2025-10-08" version="1">MVQANIDNTLGALFIGLILSAVLNGVTLSQTWFYFSAQQQREHSDPLWLRATVVVVVILDFLHQLFTSHWMYDYCVTNFGNSAALDVLPWSYYGMAYPTGVVTVIVQSFYVWRVWKLSNNVIIAGAIWSLSLAQFGAFLYYVARVFGVPNASDLSLVLGNYAILVNAIGATCDIVIACAMVFYLRQSRTSIKRTNHLLRSITIFTVTTGIVSSVCAIMVLSMAAAYPGTNIELTFYFMLTRLYANSFLATLNVRDHLRELGHGGIITTSNFVQTRTTATVHRTVSHEMDDFPRQKGTQNFDRGHSEHEDPGTVISVKVDRITDVDYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V627</accession>
    <name>A0ABQ8V627_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="35303" checksum="1CF87F24891BB72D" modified="2025-10-08" version="1">MTPDEQEVVFSVAQIVFFNTVNLIVTVTGYGAFVLGTIIAVVSLRRRTWGRSQTILLVCLLVIFTCFTWDVFYSGGFNVTDIRYTFVKTSPEGLVAQIEAADRKTLVWQYMPSWAATVNLLLSDCIVVWRAWILFQDEKFWKISLAALMIANIGINVADCIWVDIELSVEVASSTTLDWLSSIISLTVNIFATFLIAFKAWNHHRFMAAVSIRKRTRSESILLLLIESGAIYCGIQSVYAVFILLDVYTVVDIGFSQAMNVITAMSIVAAACYPIAVIILVHNENSLITEIETFQESSCAKTVDESHSMGTLVLSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6A8</accession>
    <name>A0ABQ8V6A8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_983345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="58533" checksum="8FD15780D1CF7FC3" modified="2025-10-08" version="1">MRSRNPHNLRSVHAINLSSARLGIHRLPNEILSYIFMNAIQVCDSDDPSEAAFFPLTISHTCSRWRKVSISTGSLWTSIRLCLPYSLNQLAYLRTWLSRSRSYPLDILLDFRDEEWDWEEEDHLFTHDAAKEIISVILPHSKRWRHIEFFTDTWAPIHAFLDLTRDIDDLPVLKSVALSRCNAYFARKGECFKPVELKEPIPLFAGGRLPALRDLALVGVHVDWRQSVMVNLLELELKFHAYDVLPTLGEFTNILISCPELERLSIVGWGPRLDATFTNTRRVISMAKLTRLILGFVDVEYAVMLLSLFHLPSLYELELEDVAAIVDPIGSSDASTLLTLLEASSTELNAETCFFPLHQVDYLDLRSIRSSEVVFAQFLHRFNSLEKINLSDADSALLTALGPQQFSPEPKAEISSKPRDRRPSFASSLSTSLAPCPQLVDLTCRRVDMSVLSSVISARAKAGSGVRPLQSVQFELDNIESTCHDSDDGSSIASGLSDEDRTSLLKIGVDFRINDLRSCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Y4</accession>
    <name>A0ABQ8V6Y4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="12">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_923580</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02736">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02583">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035698">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035697">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015700">
        <property type="entry name" value="RPC1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="13">
        <location>
            <begin position="244"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4475872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1401" mass="156175" checksum="330798AA9F3DF292" modified="2025-10-08" version="1">MKESVSHQAPKVIKKLQFSLLNAQDTVKYAEFEVTHRDLYTHNERLPVKDGVLDRRLGTTEKSAFCETCGQATIDCVGHYAYIKLVVPVFHIGYFKHTIGILQCICKTCARVLLEEPDRRNFIKRFRRPNLENMQRQALTKAVNTMSRKTVYCPYCSATNGAVKKAGALKIIHDKFRAKKTAEEMEKWKKSFAPALEEQKDLALYLNKAVHEDLNPLKVLDLFKRISDEDCELLGMQPKFGRPEEFIWQYISVPPVCIRPSVAQDGGSNEDDLTVKLTEIVFTNAVIKQGLARGVPTPQFMEQWDLLQLSVAMYINSELPGVPSQMGLKPIRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPQRVAQILTYPERVTSHNIEALQQAVRNGPEIHPGANFVSRGQNKKFLKFGNRKAIADGLAIGDIVERHIIDGDVALFNRQPSLHKLSIMCHRVKVRPWRTFRLNECVCGPYNADFDGDEMNLHIPQTEEARTEALELMNIKHNLVTPRNGEPVIAAIQDFITASYLLSRKDQFFDRRQVTQICCYMADANLQIDIPPPTILKPVRLWTGKQIFSVLMRPNRKSKIMVNVESKCHRWEEAKPENYPNRMKLAKDMSPNDGWLVIVNSEVMCGVMDKAIVGSGKKKSIFGVIMRDYGPHEAAAAMNRLAKLCARWLANYGFSLGINDVIPGPELSTKKDGLVEEAYAHCQRLITKAKNGELENKPGCDQEQTLEAEISSVLSKVREAVGQICMKELSRQNAPLIMATCGSKGSVINVSQMVACVGQQIIAGHRVPNGFQDRSLPHFPKHSKEPPSKGFVRNSFYSGLVATEFLFHAISGREGLVDTAVKTAETGYMQRRLMKALEDLTTQYDLSVRNSTGGVVQFRYGDDGLDPACLEGDAQPLDLDRAWQYATATSRVGAPLLPFQIIDLVDTELGTKRFATECTPTYVESLRNFLVDNVVTKLARARSDQGMYDALERSSEWDEDTDLSFGASEAAKVAVNNKVKVTTRQVKTFLDLCWVKYVKARIEPGSTVGAVGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINAAKAISTPIISCKLVTADSEASARIVKGRLEKTLLGDISSVLEEAWAPEYTYIGVLVDTDAIQKLQLELTLDDIKWAIVAAKKLKIKQESITIIPRKNRLRIYVDGVDKFYRLRELKRTLADVVVKGVPTIHRAVINIKEKDDHRGKKGDKELLVEGYGLQKCMITEGVIGEHTSSNHVIEVAQVLGIEAARRTIINEIQYTMKSHDMNIDPRHVMLLGDVMSYKGEVLGITRFGVAKMKDSVLMLASFEKTTDHLFDAAAFGKNDSISGVSESIIMGNAAAGCGTSMPHLVSVAPSLSKPRKLLFEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V759</accession>
    <name>A0ABQ8V759_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_517435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="25246" checksum="004BF0BA10328056" modified="2025-10-08" version="1">MSTLELLYDRKIYELWSWEPQQAVHQKARHQTARILPTRLTPRGNVRVAYLGPRDEEPDSLVVTKLARDNEVPALEREYRVYMDRLQHLQGSVVPICYGLYRGKVQGEKFACMLLEYYRHLMTYSIEERNFQIMRATWKLHEAGILHGSIDSMHHIVCSTAGVRIIDFSDVVDNHRCVGVIQGPHLSYPNGLAPSKTGCPELVLVDKIYGPTDLLYQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7L4</accession>
    <name>A0ABQ8V7L4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_848563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="89" mass="9889" checksum="A14AE39EC5B70EFC" modified="2025-10-08" version="1">MNFLVRLSALKISRLSLALYTLNYLLCLEFPYNIARGSASRLKPSLGNLMRTLEALASPKFAKLSPTNRAFEKALRAEDPKSQTSQTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7L7</accession>
    <name>A0ABQ8V7L7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_772504</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="537"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1088"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1121"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1158"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1191"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="239"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1335"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="14"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1335"/>
            <end position="1347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4478596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1358" mass="147066" checksum="00CDD2040B01B894" modified="2025-10-08" version="1">MGQDTGSSHRRKGSTATDNSFASSNTETGTDPDSHSPRGTNELSQIKTNTTEVTRIPSRSRSRESTSPLRKGKGRASPDDDAAQIHEDGLKAQVELIEDEDIIPAPFAFSPLTLARLLDPKSYDSLASLGGQDGLLQGLGADPTRGLHVGVLRNNRDFHENTHELDVGKTEVTRQGVGGDELGAGEGVSHRHPPLTPAIVLTQPDAEDGEGDIVKAGSTPSINSYPLKEKDPSPTGALDPQTFDASGAFHSSLEKRREIYGHNTLPVRKSKSLLALMAAAMKDKVLILLSIAAVVSLALGFFQDFGTPRAPDAGPKVDWVEGVAIVVAILIVVIVGSLNDWQKERQFKSLNDKKEERGVKVIRGGVEKVIDIKEVVVGDIALLEPGEIVPCDGVFISGHNCRCDESAATGESDAIRKVSWDDWTALRKKHAEAHESEPAHVDCFVVSGSKVLEGVGRYVVVAVGQKSFNGRIMMALRGDTENTPLQLKLNDLAELIAKLGSAAGLILFTALMIRFFVQLGTGEPVRSASEKGIAFVNILIISVTLIVVAVPEGLPLAVTIALAFATKRMTKEKLLVRVLGSCETMANATVVCTDKTGTLTQNDMTVVAGSVGIHAKFVRTLKENEGRTNAEEKPSQAAVAAATRKHIHDFSLDQSQLNTILSPATQELFNEAIAVNSTAFQDTDPNTGEMVFVGSKTETAFLKFASELGWPDYRETRTASKGKVLQMIPFSSERKSMGVVISTGGRYRFYVKGASEILSKKCTKHIVVGRPGQDRPAYEDDRIETREIDELAADNISRTIIFYANQMLRTISVCYRDFEQWPPAGMTVDEEGEADFNDLAQDLTLVAIAGLEDPLRDGVREAVSKCHRAGVTVKMCTGDNVLTARSIASQCGIFTKGGIIMEGPVFRKLSQPEMIEIVPRLQVLARSSPEDKKVLVETLKHIGDLVGVTGDGTNDGPALKTANVGFSMGIAGTEVAKEASDIILMDDNFASIVKAIMWGRCVNDAVRKFLQFQLSTNVTAVVITFVSAVASNEEESVLSAVQLLWINIIMDTFAALALATDPASEALLNRKPESKNAPLFTVDMYKQILFQSTYQIIITLILHFLGLQVLGIESSTTNNTIVQTMVFNTFVFAQIFNSVSSRRLDRKLNIFEGVMRNWYFIAITLIEIVVQVLIVFVGGSAFQVTRVDGKVWGISLALGFVSIPLGALIRILPNEPFEKLFDKLGLFGKSSEVLPTSTVDQEGWHGAISLVRDNLSTFSHVRGGRLRSSSFVVKSRSARLSRDQEPLRISSILTMAPTLIAGAVATHGYSPRGTLSDPTSNDPSKSSAALWEGKLQLHPDTSRDDPAYTRFGGDQNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V800</accession>
    <name>A0ABQ8V800_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_705150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052925">
        <property type="entry name" value="Phage_Integrase-like_Recomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605:SF3">
        <property type="entry name" value="P CELL-TYPE AGGLUTINATION PROTEIN MAP4-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27956" checksum="F2C757C53C82A7AF" modified="2025-10-08" version="1" fragment="single">HDFPIDPTTDTLSFYVVYICHFIKPKSVSSYLSGICNQLEVFYPDIRRNCTHPIVKRTLKGCKKLHTSIASRKRPLQRTELTEAFNNLHSSSSFDDHLFLALLYVGFFALMRLGELVFPDRIDLQDFRKVIMRDSFLADAEHLEFNLPTHKADRTFEGNRIVIKASSDRDDTVKIACIYVRERDSRFPGLPHLWVRSDGSVPTRSWFIRRLRCHFSDNVAGHSLRSGGATWLASLGVQVNLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8C1</accession>
    <name>A0ABQ8V8C1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Le.MFB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_844030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15550">
        <property type="entry name" value="PHD_MLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="144"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="264"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="477"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="636"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="968"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1114"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1176"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1436"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1612"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1753"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1939"/>
            <end position="2036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2063"/>
            <end position="2137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="645"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="672"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="688"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="971"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1013"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1052"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1240"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1449"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1511"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1636"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1753"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1794"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1814"/>
            <end position="1823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1972"/>
            <end position="1990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2004"/>
            <end position="2014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2025"/>
            <end position="2036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2117"/>
            <end position="2137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4478519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2155" mass="234286" checksum="299285AA4CA479E0" modified="2025-10-08" version="1">MNVEGDHVRRSSNPTTNVHRLSPKLTPSSSAVAATQDELSGTGSNRNHGNGFHRRGGGGAGRKNGAVTSSHINGVVGRKSGRSTSPVASSTLVSTSSTSASAIPHKPPRSPTPTIRTSASTIPTKRKHPSTLDGRPASDEDSESIRCICGFSVDDGWSVGCDGCGRWVHGVCFGFEAKDKENLPDHWWCWECDPSLLERIDREKARSLQIARLATAAGDTTGNGRRRSSPGVDRKARKINIATGAGPFLSPSFGISPNFPSIFPDHGSHKRKRTSVAAPSPLTTGSALPFPPSTGQPSSADDFVDIDESWSHSYIDISHDIIPESEARERLRKQASEWRGISAISPVHDLSSKPGWPYFNTTPVRYPHPVSPSVSSVSLRPLNSSPGSVLPPSYAVHTTHPIPSQSLLAPYPSVITSSSTYLQDPLNAYATLGMPKPRVHLIGPPLDVSLDARGKGGKARFVRSGCQPNAVLRPVLCDGTREPGSASDPDHLHRRTSTGEQAHSSSHSAHPSPQGTPDSLSFAIFALRDLKVDEEIVLGWEWDDANVVHLLPALLQDKDIFPPAQLAAYKLQMANILRALGATFTSCACGDRAQGCVMRKMKEFVDEVDDWDSEHELQRERELRNVDSGIERSEEFRHIRGMQDGQGSVNSTSETFSDHLSPSHPTNSHYQPPSTTGSSAAPSMTPPFESSLSSTIPGNLQTRPQTSSFSHSSVMYARPLSPSLIQQEQLEQEVELQTQSSAHPTFQRLNKHSIASSSQIPPSSSTVDLGPLIGVPRGFRTREKVEGSGGLGGVEMDTDDSVEVGQDVHTKAYVRLGPQDEKRRNLPALQPNLDTDSHILSMYADQATQPPAHNFPLHPYAYPIHGITPSPPSVYSYGTLYGTPYPFPHTTYPLYIPHPPGNPPYNPERNGGKEELFWGDIPSIAGVDKGKGRALDIDILAVDDEDNDQISVGRNNKEDIDVVVNEVSTRHPQRHRRKQSVYKRPKSLETLHLSDQVVEGSEIPPKMKRRWQHERNESQSPVEVKRTQRAYEDMQVDDDGRSRGGQDPPTGDLSTTTSPAMPAISTTHAPVVCSPSTTSPLLTFANLSLLSPVPVSSSSTSSLYPFPDRQLPSHKSTHWWDVSPQGSRHQSKSPMPRAQFRSQSPPRHISPTRRAITDPLAALAAAAAAARPISPVPNRIYSDSRSKSRSRSSRSEKRLGTISTLNEPDHERYSYDTATPYLGSPRRSRRMSTGDGECSDSDHHHPSHFRGIEDFDHDNQDVRQSRAPSMLENHDAVLGPGGIRVLSSPEHEWLPLRKGVSTPTESLYGVAHVLSATDSIDHSRFERRVIAIQDESIVDSRSLKVKAELLNEEYIPSSTHLVHQNYEPVEVVDVERPRHVGTSAEPETALQITQPSHLVPTLHPPLAFPNELPRSDLLSPTDSYVAPLSPLTPPATNLKDIPPWPASPSPRNSPSVSDPVQKSSLPPTSLVPDAIPSSELQPAQHNEARPSTLVSAGPHAPTEWEPFPLTPSHSPMSALSSVASSSPITAHFTLHAIENKENDCDNECTAQVTRSSPFSSPLSSPMEKLISLPVYSAPIEQSSSSSGPVHTEVDCPPPNTIHRIPSELPAATVGSFQSQPDPPLHASIHDVPALEHSSSMSPLHSPGNDSPTTPKEVDSDEVETMDVDVMNAHDTETNDEQERKAQLTIPSINANLSPPLVSVRAAINSEHIDDSHSYFPLASELAPQTSPALATSPPPTTFAASKVKKMSLKDFAIRKRRQKEEEEREKKEKEQDKGHNVEQKPVDWEDAIIIEDRQKVQESHVEVEAPVDSNGEDDAEILPETDGLSAPPAKYVVPAVLESSIEQHGHNLPKSDVDVIMKASETLNKLINSSSMSMKSMTVAHEYSASPPHCDVSTTAKPPPIVSSLSASPNIASRPPRGLITDPIIIADSSLSVMTREKTTAPHSVPEDGEIEDGDSRTMFRFSPSPKHPSSNIKSSYLLSTSQPKSYSPPPRAFKIHENIVTNEQRSRTPPTQPRSFAARSPSVSSVPHGSPPIRRLAIAPVANGLSPKVAANVTSTTTTSAPFIPSAPPSANPALGRTPPSGPRALRQLQQHQHSGGGGPRNGNAYIPRGLPYDRDRFRDHGGDFGRERDRDLHWNAPGVQRLRTSENRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V931</accession>
    <name>A0ABQ8V931_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase pc-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_896805</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4481321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="591" mass="67571" checksum="20782373FC5A486C" modified="2025-10-08" version="1">MTFLTPGIIYITRALAFPAFFTVGVVAARRFLETHTNLVLPTWIFVIISVLSLPALITCRILLRDWRQKRDAAAIGARIAPRVKGKWFANLDLLKMMMNNYYKGYPADGLIDIMKDEGPVFNMNILWENMVFTCQPEHIQLILATDFNNYAKGGRFQRNMSAVLGAGVFNSDGDMWKFHRSMTRPFFSRDKITHFDIFDRHADSAISLMKTRFRAGYAVDFQDLIGRFTLDSATEFLFGSCVNSLAAGLPYPHNVAPTVVSAFSLARDFSNAFLEAQEAVSSRERFSMIWPVLEIHKDRTKEPMKVINAFIQPIVDEAVAKMRSQKELGQMSGLAADIDDNETLLDHLVKQTEDPVVLKDETLNILIAGRDTTAATLTFVIYFLSMYPETMDRLRKEILKKVGPSQRPTYDDIRDMKFLRAVINETLRLYPVVPFNVRECTHATTWPSPDPTQPPIYIPAGAIVPWSVFMMHRRKDLWGPDAEVFDPDRFLDERLKKYLTPRPFIFLAFNAGPRICLGQQFAYNEMSFFLVRLIQNFTSFTHLPDLCPPEFQVPSEWKSFSGRKGIDKFFPKMTLTMYSGGGLWIKAQEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAM2</accession>
    <name>A0ABQ8VAM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GroES-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_769620</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08282">
        <property type="entry name" value="PFDH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF3">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="8">
        <location>
            <begin position="187"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4484491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="40894" checksum="EAEDCC18C0C1F561" modified="2025-10-08" version="1">MRAVVYEKPFTVSVLEVPKPTILHPDDVIVKGDCSCRWIIDSDLHMYEGRTSAEPGIVFGHENMGIVDEVGGGVTLLKKGDRVVMPFNVACGRCINCEEGRSAFCTVVNPGFVTLMGTYVAMGPYPGGQAEYVRVPFADFNALVLPPGTEHEEDFALLADIFPTGWHGVQLSGFRPGESVVVFGAGPVGLMAAYSAIIRGASNIFVVDRVPERLQKAKEIGATPIDFSASDPVEQILKLRGGKEVDRGVDAVGYQAVTSDGKTEQPNVVLESLIRVVRPTGGLGIPGLYVPNDPGAPDSAAAKGYISFPFGFKLFEKGLSLGTGQCNVKAYNRYLRDLIIAGRAKPSFVVSHNLTLDAAVEAYEKFDKRIDGYTKVLLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB07</accession>
    <name>A0ABQ8VB07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HCNGP-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_445284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012479">
        <property type="entry name" value="SAP30BP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464:SF0">
        <property type="entry name" value="SAP30-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07818">
        <property type="entry name" value="HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="25239" checksum="AEE9BE89AAA78C98" modified="2025-10-08" version="1">MQQKKSQIVIKRPRTSQRPKGHVTIDSAQPAPTTPMAPVDNPASTSTAGSSQTSSTPEPEDVHLARIRALLCPPPIPGLADWGIPPEAETACDPELEEKLKQFHQLKSLPTPKHFNDTLMSNRSFRNPHLYAQLVEFVNIDERTTNFPKDIWDPDEVRDGEWDAEKIAKYQKIRSEQQSQQSKSRTHIEFSSGKDIRSHPYANAPSSGSALGGRRQARSSGGPSRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB27</accession>
    <name>A0ABQ8VB27_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PRP1 splicing factor, N-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_839244</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="5">
        <location>
            <begin position="16"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="931" mass="103337" checksum="E85BCA2EB52A3FFF" modified="2025-10-08" version="1">MASNKPNKLAFLSMPAPASYVAGLGRGASGFTTRSDIGPAREGPSAEVIAEAQARRGEEAEVDPEQFQDPDNEYGLFAGTAYEQDDEEADKIYEAVDAAMDARRKARREAQEQAQLAKHRAERPKIQQQFADLKRGLSAVTDEEWESIPEVGNLTKRKRPKYERTYAVSDSILAGDRSRGEYENTLDSLQQQTGGLVTPAEAGPTNFVEIGQARDKILSLKLDQVSGTSTSSGLSTSIDPKGYLTSLNSVVLKSDAEIGDIKRARMLFDSLIKSNPKHAPGWIAAACLEEHAGRMVAARKLIKQGCEQCSKNEDVWLEAARLHNNEDAKVIFANAVQHVGQSVKIWLAAADLEHDVKSKRRVLRKALEHIPNSVRLWKETVNLESSASDARVLLSRAVEVIPLSVELWLALAQLETLDKAKAVLNKARKAIPTSHEIWIAAGRLLEQEASMMGVEKTNAEKKKALDLVDKTIEAGVRELRRHGVLLTREQWLKEAEKCETQGSVLTSESLVKATIAMDIEEEDRLDTWIDDAEGALSRNMVGTARAVLAYALKVFPDKKNLWIRAAGLEKAHGTSESLDAILTEAVKHCPQAEVLWLMAAKERWLAGNVQGARDVLATAFDANKESEKIWLAAVKLEAENGHLDVARELLIRARSTADTERIWMKSATFERQQGQLDAALETLATALRKFPKFSKLYMVQGQIYQSQNKFPAARASFAAGFKACPKEPILWILASRLEETDGKSIKARALLDKARQVNPSNELIWAEAVGVEERSGGAAQAKAMLARGLQDCPTSGLLWTMSIWLEPRPQRKTRALDALKKSNDNPLIICTVARLFWAERKIEKARQWFQRAVPPRPDDSVDTGADIGDLWGWWLKFERQHGTEEHREEVRAKCVTAEPHHGLVWQAIAKDLKNNGKSIREILEMVADVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBF3</accession>
    <name>A0ABQ8VBF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_838185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="361" mass="38677" checksum="C6AFA736648F7487" modified="2025-10-08" version="1">MAPSTRARSANNTPVKGQDTFASELDTIATPTRKVPHCSKCKRPRAGHPRSGCPFVTPTDENGSDRSSTNLTDALGSMTLDGQETPPPKTPARRTGRRSLGPAPPSVPVEFEDTKQVIRERRRSEKATTLAHSQTLQSLSDSDLEALLLPADTDVSDDGKGGEAGEEDRNIVHWKDRIGMLSAGGDIPTRAIMPGTLVTPSPWSSFASIPEENKDGILRTRPPSNASSSSTETISVEVVSPSSTTAPRPLSRTMSMEERAGFIAHLEELSSAKAYVLSRADLIELRGRAPKGLYTRFLMDEEAGRNVLVVGRDEVDTERLYQTLDAEKQQAMYATRGVSMKSAAGGAVVGAVATFTGLAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC11</accession>
    <name>A0ABQ8VC11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_896309</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="405" mass="45930" checksum="71A8BE96EB83DA94" modified="2025-10-08" version="1">MSEGSTEERHFSNVVATFRKYTSYHLAANNRRRKDLFTLPKADRELLEQLGYKEKLDQVDKAILANEQFLNKIVIDPEIFGDDGNDAFEEGDEEGEAADPSISARSHSHSHSHSPHSHSHSHSHSQPHSLQSPKEYKPTEFDMDKLRSTLKQFVRDWSAEGQEERETSYGPMKDALLAHFSDIPKEERRNFRVLVPGAGLGRLAYDIASLGFACQGNEFSHYMLLASFLILNKTERPNMHTIYPYVHSFSNVPDRTSMLRPIKIPDVEPTLPSGSVFSLVAGDFEEIYGGESDPNEPQAGLWDAVMTCFFIDTAKNIVNYLRIVHKILAPGGVWINLGPLLWHWENNHTNDPSIELDLVEVKQLAAMVGFEIENERTIDATYTTNSQGMLGYTYRTAFWTAKKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCH1</accession>
    <name>A0ABQ8VCH1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_836768</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF11">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="79"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="384"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4487444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="473" mass="51499" checksum="68DEF40A1C3392CA" modified="2025-10-08" version="1">MPPKKAKKISLNEFLETAPGSWADEMDELPSAPAMRSDDDQGHQNDRYGRRSDDFLASRPDRAALPPREDIPLPTQPPYTAFVGNLPFDLIEAELEEFFTKTKSVKIIKDRDDKPKGFGYVEFEDLDGLKDAISKSGAAFSGRTIRVSVAEAPKERSGFGGNDDSKFDNPWRRDGPLPDVSSSRDSSRRRFDGPRPDPLPSVSEDANDWRSSRPRAALPEPETPTGSMRKKPIGFGSDNSGAADRDEVWSKGSKFKPAEERENAAPANRFGSGRGRGDMGPPRDPVPEESDWRSSSRARPARDNTSPTGSTPPTPQMGRRKLELLPRSGNGSNVPSPLSSPKIGPTPPTSGSRSNPFGTAKPVDVTAKDIEITQKLEKDRELNRISMSRTSSRTSIERPISRNHTPPASAASHSQPPSSPPAPASKVIPQGMSANVRPAFSFANAAANKKKAEEAETIRKEETLAEKLGEVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDX7</accession>
    <name>A0ABQ8VDX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Scavenger mRNA decapping enzyme C-term binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_766621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF5">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="23"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="113"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4489767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="176" mass="20439" checksum="6B479B8BF10C81C2" modified="2025-10-08" version="1">MRTKALPLHLSLHEDSKYDQSRAFCNVSTENGFEVMWEDENLVTFRVRDPACEHHFQVIPKEHIPSVRQLRKSNVETLKAMVNVGHQLLEQLAVENTMRKMGFHIPPFNSMGHLHLHVQALPYKNFSKKLKYPIVDGFKPFQKGFSWFVEAHQTISIIQQDRSVGLFPCEEARSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE73</accession>
    <name>A0ABQ8VE73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_921015</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="9">
        <location>
            <begin position="387"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4487479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="857" mass="92638" checksum="DCDAC297E172E064" modified="2025-10-08" version="1">MLSAIAARKAATAAAASGGVKPDSYSISASTSTVSTSISIPTPKSKSRPRPTPSKRKHSSTGAPLDASITGKKRRRREKDVLEKPRAPRPRYFEQGGIAATEGEDDEEDWDGSNSDVKVETTATRGYSPSRPISPEDSSDEEGVQNGSIQPEPQTQTQSQVLLTTFVPIPGQNTFYLSPDELSLVLSSENSTVPATLIALGHSENLTLLGMYRLTVIRGSIEICGAILRSRVHPETHNVFAPRSSPVPSIRVVSATPSSPLHALLPPGIQHEIAALVGDPVLVLLQELRSGVEALGKVCKTFDGVFEVHPRDVLNRNRELEEEAEDVLRLRAVRIITHQSKYVSPLVIPASWEKALDEVSTKNWDDDHDDDSETERKHPPNIYLIKGPKKVGKSSFARTLVNRLLSQHNTLAYLDFDPGQSEFTPAGLIALTLVSDPVLGPPWTHPSVPVRAHFIGAFSPKGCPSLYLEGVRDLVRFWLEEVCWEGSKSAIPLVVNTMGWAKGLGVDLMKKIQDVLTVDGVEKASYETSFGSRIVGESRAVMHVYEFGQSENEMGNGRQREMDGLPLERSSFFGEGGTSRVHHLQHPLPPGIQIHDLEPVPVSASSTLSLLFSAADQRTMNIMSYFHAVFPSSSSFSSSSYTTASHWDASLPLLARPPYQVDVGRALDRVFLLGGGGEVIRAEIESVLGGAVVALVRCEPGTLDAIDDNDDSTQGQNQIPYFPTSNSASSYPSPLTSSAIGLALVRSVAPGGSHLHVLTPLPLSAILSSSSTSPGLNMSRSLDMGTGGAGARVLVKGEMEIPIWGMVDFRRLGGRGANRGEGDEQRDIPFLQWEKGVGVGAERRRVRRNLMRKGQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEA3</accession>
    <name>A0ABQ8VEA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_766478</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4491097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="516" mass="58419" checksum="14F08E91608C0B7E" modified="2025-10-08" version="1">MCLIIDIELTVILVLLLLVIVIGFRGWQCFDLKISLPPGPTRLPIIGNLLDMKTSSEWIHYHQWCQENSSDLMYFSAGSLSVLVLDRLQPVVELLEKRSALYSNSFSAWTNVCLRIGWNWSFPFRYEQWKEQRKIIHHEFHSKAVAQFHAQEIEAVRKMLQCLLYSPESWYHDLTQFLGALIMLTIYGIKVSSEDDPFIAVAKRATHTVSLATTPGRFFVEVIPLLKHLPTWLPFTRFKRSAVMWQADAIDSLLKPFAATKEMMASGATISSCASRGLQKLEGLADGHNKEEILQWALGSMSPGWSKHSMMLSALRSFFLEMTLHPNVQHKAQLELDNVLQHQRLPTFADRSSLPYISAVVMEVLRHHPIAPLGAPHATSADDTYQGYHIPAGTIVLPNIWAILHDPVQYPDPFVFNPDRFTSMSPYDGIARDPSAVFGFGRRICPGRHIALDVLWITVASILTVFTIDQPKDEAGNPVRPLVRYEDKGVIIHPLPFECNIQPRGQKETLLIGHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VED7</accession>
    <name>A0ABQ8VED7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_920261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046300730" evidence="2">
        <location>
            <begin position="23"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="24286" checksum="70300C8165126F91" modified="2025-10-08" version="1">MLALSLLRLTFLLLSSLIAVTAAPLTSMTDMTARVEKRQVKNILEAKILIAPNSCEESSIYFGRRNSFQPVQQDQNTEIFKGKHSNEKKSYTNPIASVKFGPTTRNMVFQDLKIVVQGSSKWDYIAKAMKYLQTKATESQLEFKFETGGEERWQKLLEKCGGKGPEQQGELKTSEGHTSSGSNEERRPSYGEFGKKGKMPTFTDILVGGSAGDATESKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEW4</accession>
    <name>A0ABQ8VEW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_766146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29123" checksum="4C42E6AD859C3332" modified="2025-10-08" version="1">MSNSTTHENLLIPRGLNEPTPFTQSVFVLFRALDLPLQYAILSSRSLAAPLIHALGGTSISLTTAQPFFLMGTNTGLSPQRAILFSMAIGSFIKQSYWVIAISQDALPPRASAYIGTFNALANSLNTVLFVNTATSVLNSAGGDETRLSAPTIVGISLYAIGMLLEWGSELQRLKFKKNPRNKGRVYTGGLFALARHINYGGYVLWRAGFAMAAAGWAWGAFIGGLHTYYFVKAGIPELDDYCSKKYTGQWAQYKKAVSYMLIPFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFB6</accession>
    <name>A0ABQ8VFB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMN-dependent dehydrogenase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_840739</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF148">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE (CYTOCHROME)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="102"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4483149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="56084" checksum="231ECD0F341F7D01" modified="2025-10-08" version="1">MLSGKEVAQHNGRESCWIIVHGKVYDVTEFLNDHPGGSRIILKYAGKDATQEYDPIHPPDAITSNLPPEKHLGPVQPDTVEKVEIQITDEEKERFERIERRPSLSEILNLHDFESIAKEVMPVKAWAYYSSAADDEITIRENHAAYHRIWFRPRIMRDVTSVDFSSTILGHKTSMPIYITATALGKLGHPDGELILTRAAAQHGIIQMIPTLASCSFDELVDGAQPGQVQFFQLYVNKDRAITKRIVQHAEARGIKALFITVDAPQLGRREKDMRQKFEAEDPAEVSKTRKDNVDRSQGAARAISSFIDPGLKWADLNWFKSITKMPLILKGVQCWEDALEAYDQGLAGVVLSNHGGRQLDFARSGIEILAECVKHLKDKRGLTFPNEKFQLFVDGGVRRATDVLKAVALGATAVGIGRPFLYAYSAYGPDGVDRALQILHDEFEMNMRLLGAPTIKDVVREMVDASNLSSHVVAVPNDSLFNTNYEVMQHAVLKLPLKAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFE9</accession>
    <name>A0ABQ8VFE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="350" mass="39852" checksum="F13E2D051CEE1BA6" modified="2025-10-08" version="1">MAHNHSANSSDDDEAPETLTLTESKGAFRKRNAEIREVEEARKKMRKDKRRERERIFKERKQQRQREELKAVKSRRVSDDAEEEEDDGGEGDEEEDGENDAEKRMLRAMQQAEEEEESENEVDNVEEGESVDEDVDEDDIDAETREDVDEDEDKEMVVDEDDEDEDKEMLVDEDDDYSHEDEDEEGSDAEMFSVDSSPPRSKSKSTLNAKSSMPKLKTNHLPDHLFASAFSSGSQKNQSKNNNLSLSGLSTTKKLQEKKTRRRKRSGGIARDHIVGSRLFRTLPKPDTAPRASAAMVPSSKVNKFLDRSLSLKGDKKARMRGWERRAANIGSLRRQGPAAHFVRGASYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFU4</accession>
    <name>A0ABQ8VFU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_795243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="386" mass="43921" checksum="3FB6D41EAE2B855A" modified="2025-10-08" version="1" fragment="single">MFSGAHDFEISHSNFIVRESHHQTEDIQMAIQPPGYIRGMTDCPRSTLAFTGRNEILESLEKFFLSTTVPTNQKVFLLYGLGGVGKTQTALKFKQRLSSKKRLTKIYFIKANTEQLIQASYFDIAIDNGIVQAQDWHAGIHWLHSNQESWFIIMDKADDPKIPLTKYLPSCGHGNIIITSRNPDLQDVTTQSLEVQNMVPTEGIQLLSLKAVGGSLTAEQEKKVAQIAKRLHYFPLALVHAGAYIRQRKCLSTYLERLQNLRRQILEKEIPQSLDGYSLSIYATWKLSWDELSDQAKALLSVCAHLHYEKIPRLLFERAMKNIDNVYMPLGPSNAVDEARIILSELATFENVWDLNQFDEIVIEANSYSLLQVADEGLYEIHPLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGB4</accession>
    <name>A0ABQ8VGB4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Sec24-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_920831</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF4">
        <property type="entry name" value="SECRETORY 24CD, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="6">
        <location>
            <begin position="125"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="7">
        <location>
            <begin position="221"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="9">
        <location>
            <begin position="475"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="8">
        <location>
            <begin position="576"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="5">
        <location>
            <begin position="721"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4488588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="865" mass="95394" checksum="96FA5CCE226ABAE3" modified="2025-10-08" version="1">MYNPAQSPHIPQPPHSAGRGIQGLRPRIDPNQVPSAVDAVESDRQHWEKQPYLTLPGTRVPLATTDFVAVDQGNSSPKYVRVTTWALPHTSRLASECNVPLAAVFQPFAEGDEPIPLLDPGPSGPARCEKCRAYVNPWCVWTAGGSKWKCNLCTHETTVTPEYFSNLDGNGMRLDQMDRPELCKGTVDFVVGDEYFASNPPQRLTPPYFSPTPLPTGVRAPQSLNFVIALDVSVEAVQSNFLYAACISLLKILYGGPDHIDEEVMLDSCFPSGSRIAIITYDSTLHFYDLTTDKVPSPMMVVSDVDEVFVPLYNDAFVDPWEHRKSLEALLQSLPQRFVNTSDSRNALGSVIRAGQGALSNRGGHIIIFLSTMPSVGIAALHGQPNENELYDTDKEKVLYKPRDPLWKQIGEECAEEGIGVSMFLGNSKFVDVASVGAVPSTTGGDIFFHPRFDLLRDSPVLESQMQRLIRRTTGYDCIARVRCSKGLRITNHHGNFYLQNSTDMAFGILDADKSFCVSLSHTATSMTSSGLSPREYAYLQCAVLYTSLEGQRRVRLVNLALQVVELAGNVFQFADVDTCMNYLTRTAVSSLSSQKMSLIRDDLTENCSAMLLGYRNKCAAASRPTQLIIPETLKALPTYTLGLLKSKPLKARNIASDVRNYFTHRLLSMSVRSTIQHLYPRLLALHDLDDTIALTLTDTETPGVGGIPRSKAANSAVLLPSTMRASHEWMVANGIYLIDNEETTILWIGSSVSPQLLIDLFETADIFSLDPHMVKLPPLATRFSKQVRNIIATRNAERGGRAAKFFIARQNLDAAEIEFSDMLVEDQNNGNMGYLDYLTMVHKQISAVLTEGGSLSSAGVRSPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGQ5</accession>
    <name>A0ABQ8VGQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_866941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="19918" checksum="0949F863A1133F93" modified="2025-10-08" version="1">MTRTGLVQEAASADPCAGQGPKEVSGDGEQDLEVGTDDESALRKIQKPKGEVSRPGRGGYNLRVELKWSAERFDKVKAYIDKLVQEHLDCTEPLTKQIASKVEEVRSLAVKKFRFLDDYHDYWAVDDFVRCHLKYRKQALQKISLQNEAAKTRKEIKEVRQRLAQAEKEARKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGS2</accession>
    <name>A0ABQ8VGS2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF914-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_830001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="43905" checksum="E5FDEEE3ED96CB85" modified="2025-10-08" version="1">MSSPLAKDSKDFDYAAPALESQSIIEAPPPKRPPIEFSSPAAFFKSLDARIKSIFTRRFLFSLFAGQIVSLCITCTNVSTTELMLRNWALPTTQNVFFYFALFATYTPYTIFRYGFKGWLEMVMRDGWKYIILAACDVEGNFMVVKAYEYTDLLSCMLLDAWAIPVCLFFSWLYFRTKYHWTQLLGVFICVLGLGLLVCSDELTKKDYEALSRGKGDALMVAGATLYGFTNATEEFFVRKRPLYEVVGQLGMFGFIICVSQAAGLEHNDMHTATWSGANVGLLLAYTSAMFILYTVAPILYRMASSGYYNLSLLSSDFYGLIFGLGLYHYQPYWLYFVAYVIVVIGLITYFWYSAPEDQAELAPEAPTYIQERREDLRGPQKIAGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGW7</accession>
    <name>A0ABQ8VGW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb/SANT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39679" checksum="B58922014851C0AC" modified="2025-10-08" version="1">MAMKWTELETWGLITQIKVVENFKNSSGDTKNAVHQRIAAALWPGGDGDITKMASRVKNRITWLEKTFKDKVKLLKKTGEGMEEWHYIAPSGPDHDTDQHAVSIWDRIRHEFKYFPDLYHIWSTKPNLVPICATTGVGPNRSEFVLIQQTSTKTIPSQPSPPPATPDVLMLVPSSSDPFSSGGSNDSPINSPSTPSSAHKENVEPPPSSQRPPRSSAFSSLAPPVNGDKVPITVPQKLGFEDKMIGLQQEMMKSMEKRSDDAQTLKRLREEQKMEDQRLKHRKLLQDGRGQLLAEFQAGLWTAEQYREERKKLDMVFSTPQKPRHVPPPPPRAPSPDWDENLFDDDLEGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGZ7</accession>
    <name>A0ABQ8VGZ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 15">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_372612</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 15"/>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23283">
        <property type="entry name" value="beta-trefoil_MIR_PMT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF50">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="661"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="349"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="418"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="490"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4491666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="787" mass="89301" checksum="24CADD2B7425E901" modified="2025-10-08" version="1">MSGNFRARRPASPPPGAGYPPPTAVPLTAARFPHPRQDHLDADARREAASKGFAPGRLKSNISSGGLSITSGEVKLLIGLVLVAAAVRLYRISRPNSVVFDEVHFGKFASRYIKTQYFVDVHPPLAKLLITLAAFLFGYDGHFDFKDIGKVYENVPYVAMRMVPALLGVATVPLAYLTLRALDCRATTSLVAALFITFENGLVTQSRHILLDSPLIFFTSLSIFSWVGFCNEDKHKPFTDSWWTWLVLSGLSLGAVVSCKWVGLFTIATVGFSTIYQLWVLITDIRIPPKLFIRHFAARALCLIVIPVLFYMTMFQIHFLILGSSGEGDGFMSSEFQHTLGGRGMEDTFADVALGSEVTFRHVNTQGGYLHSHPSVYPGGSKQQQITLYPHRDHNNDWRIVNATHIDPPVISESPNGLRYITPGMRIKLRHISTEKMLHSHDIRPPVSEVEFQNEVSAYGAPGFQGDANDDWILEIDEVASRDRRDREAVKRLRTLRTKFRLRHALTGCYLFSHKVKLPEWGFEQQEVTCNKNAVRANSLWFVETAMHPDLPADAPKVNYRLPGFFAKFLELQQVMWTTNAGLTDRHLFDSRPDAWPRLRRGINFWVKDHRQIYLIGNPMVWWLSTLAVVAYVGVRGLLILREKRGFKDFNNSTVVKYDGVCGFLFMGWALHYGPFWIMGRQLFLHHYFPALYFAILLSCGIFDFVTSSLRPKIRLQIAAVLCILAIWNFSKFSPLAYGTPWTKQSCEAAKWGKHWDFSFIAIQYRSSTTYTIQGHRSNHYKRSLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHB6</accession>
    <name>A0ABQ8VHB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_313599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="350" mass="38855" checksum="75525E34CD2209D8" modified="2025-10-08" version="1">MTLPRSFSRASSFSGSMITRHESRYSMRPSTSNSFHALPPILSGSSVHFNFQSLMISSGKSPRSRRASRLSENPPALPPLPSLSQPLFPPAAEAAQKDLFQIPSLRHPNSPYVPWDSPMRRQIFPPLTTESSESLSSHSECSRSGARAPQPLIISDDDHKLVRVSRGIRKVHRTVKHVAGVAKRMFMRHKHVQASSVPPLTINTHISGHSVHPPAYPPSPGVASLDSSNTRSLALWLDARHQEILEWDADSRHFMSLEDYERRGSWINLTGDRTFICSLPGCSIHSQLINAVTSIELELDISCCDQRVDEQSQLENTGSGRASHDSDKTAISEILLDQKTKDFSRTTLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHH0</accession>
    <name>A0ABQ8VHH0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_895601</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="161"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="498" mass="55235" checksum="76AA4B4F322C9608" modified="2025-10-08" version="1">MVVRRLPKTIKQLLEPGSSSAAALTSITGHVRSIRRQKRCTFALIEDGSTSKGLQAVFKHGVRGEGTSTAMVEKLRQLTFGAGVIVSGRLVESTGPGQDVELVVEGLDGVEVVGRCDPDTYPLQPHHSGASSSSSGKHSAEYLREHLHLRLRTPGIQHTMRLRAKVKEALEGYLTGEQEFVYVHTPVITGIDAEGGGESFRVGKGEEGEEFFGRPAHLTVSSQLHLEAFQAALGRVYTLAPCFRAERSMTGRHLAEFWMLECEWGGESPSCDLHGLCTFVEDMLRYTIARFLHSGLSVSPPDADNELHRAAFSQKPWPRITYIEAIHILQQAQPLFTYPPTLGHSLQSEHEKYLAEVHFKSPVFVMDYPRGVKPFYMRVNPRTDMETVACFDLLVPRVGELVGGSVREERYGVLRSSMVDAGLIPSPPETEIIDSSSPHSPKKPLNPYEWYLDLRRHGSVPHGGFGMGFERLILWLGVGIANIRESVGMPRWKGWMGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHL4</accession>
    <name>A0ABQ8VHL4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="53462" checksum="5BDCF7BF70453C97" modified="2025-10-08" version="1">MIYELLRRLYKPLPPLGWKNIAWLSFIISTGHFLARLVPNFVILRQSPPSFPDLPVEVLTEIFQFATYLHEAENILPLDPFIPQQISRNALGPNTALSTMRTKCALVLVCRSWRNVAIPLLYRHLVIRSPQRAIYLLSALESRLPMPVDATTPTRPSEYGRFARHLEIYTHSRGSNAYNFLLTICHIIQKSPNLRIISGSWNHALPAGFPQSVSQMCGPTLQGLLWSESCPDSPTFAKFLSSFQSLRVLDISRVPRHRAEDISLSLPSIQDLIISTHTGSMSLATSISMPRLHTLVLRLESNAPESSTYIRKFLKARGIALRTLHILPSLGIDDQNILYNFHIPFRDCTCLETLTFHVNHTPSFHHPTVKRVGIHGLKSEAFEHGKTNSGKTCLKTLATRSLYPCLETVRTVDYLVENHTLSLGHYILWSEKFERLGVDFQDGAGIVWMYTEALDIDGGGESSNDRSCEEATLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI48</accession>
    <name>A0ABQ8VI48_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_909757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="8"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="47473" checksum="4129F25937D1E080" modified="2025-10-08" version="1">MSQRLVHLVYIHGFRGDETTFQAFPTHLQQYLTDHIPTRLNLKVQSSLYPTYKSVKPISSATKTFIEWLRTQPPGPVILLAHSMGGLLAAEAATDPSNVHKRIVGLIAFDCPYLGMHPHVVITGIASLIPKKAEGKMKTETELNPSPNVRIVDRTKETENWDDSEKQDEYSPSPSPSQLSLSTSATSTSHNKSDSLISRTMKFVSSHSDDPLVRWTRKHSNEPFSAGKRWVVEHFQFGSCMFDPSGLKDSAVTESDGQQLLDNNDEALIGAGIANPSENPLGSVQSSVEPSASSGNSMLLDSVPEAPVALGPKTKSENKAYMKAAEKELRMQQKERKKEIQKNQKAAQKERDTHAKAATKDKVKGERHFVVLPTGLGAILGGGDHWEQVVIGGVDDEVAAHCGLFIPEQNIDYAKLVERVGLRIIEWCHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIJ1</accession>
    <name>A0ABQ8VIJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosome recycling factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_828048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="4">
        <location>
            <begin position="95"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4495456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="245" mass="27876" checksum="4E6B29F2717DDF16" modified="2025-10-08" version="1">MSLRRAALRSSSILRQHSYLIVHQNFISPRNTSIFPSFLVRTYAKAGKGAKSTANLVPRSKQPITDPEAQEEYASAEQKMTAAVDWFRRECASIATRTNGRVTPDLLSSVRVRFPKDEHAFKLEEISTVGVRNASELVITVFEEESLKHVERALYDAKLPGLSSFQKQDSRTLKIPVPKPTVEARKALFAAAERQAEDTRTQIRRHHQASLKRGKYEKHSVELDEFQKLTTRFVNNVDTILKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIK9</accession>
    <name>A0ABQ8VIK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pheromone receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_707672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="20620" checksum="3593D303628190DD" modified="2025-10-08" version="1" fragment="single">MLPYALKIVWFSLSLSGLLSCWAVLSAFAVAVRSHWLALLYCIGCTILQGTFCLGLIWRMDPSLMPRSFCIAQTLLSGLASFMLTGVSATFSMITSLAVLRPGVCSLASSKPFIWHPIYTLTLIVFPLLASIAQITAVLKLDAVQPVDDFACDATDPEWVRFLSYAGVPLVFSIPFSCLGLMALVRMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJC4</accession>
    <name>A0ABQ8VJC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_761847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="128" mass="14471" checksum="217E044A2D0116F6" modified="2025-10-08" version="1">MPSDFSLTPPTIDKGTFAFARIHGEICLVQVSSSTPAQSALATVDVKIFRHEFITIFRLSTTTTLHPSDIQIMENIDEKLVYHEEENGTVFLARDVMERLRKLTLPVFPISPRRVARPSSWRQSIGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJQ0</accession>
    <name>A0ABQ8VJQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Saccharopine dehydrogenase [NAD(+), L-lysine-forming]</fullName>
            <shortName evidence="13">SDH</shortName>
            <ecNumber evidence="4 13">1.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Lysine--2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_763702</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="EC" id="1.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.7" evidence="4 13"/>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12188">
        <property type="entry name" value="SDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027281">
        <property type="entry name" value="Lys1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF23">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE [NAD(+), L-LYSINE-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018250">
        <property type="entry name" value="Saccharopine_DH_Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 13" id="KW-0520">NAD</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="15">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="14">
        <location>
            <begin position="175"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR018250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4494329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="369" mass="40656" checksum="CC0C8A5E3CF6AE32" modified="2025-10-08" version="1">MTRPVFWLRCEKKEFERRAALTPTTAKKLIDAGFQIIVERDEQRIFDDSEYEAVGCELVENNSWPSAPKEIPIIGLKELPASTDPLPHAHIQFAHCYKNQAGWADILSRFDRGNGTLYDLEFLEDANGRRVAAFGFHAGFAGAAAGALALAAERRCEKLGQLNPYPNEEAMIEDVKKSLGGSGKGVKALVIGALGRCGRGAVDLFKKIGLEDDDIIKWDMAETAKGGPFKEILDVDIFINCIYLSSKIPSFITRDTISAAGKNRRLTVVVDVSCDTTNPFNPIPIYTINTTFSEPTVRVDLPSELPPLSVISIDHLPTLLPRESSEQFSADLLPSLLEFPDRNTARIWTDAYKLFQKKLGEAAEAKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKD3</accession>
    <name>A0ABQ8VKD3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_726648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="128" mass="14361" checksum="C9C396C4D29FF56D" modified="2025-10-08" version="1" fragment="single">ATGWHVGWLIGPEYIIRPTLAASMRIVFCSNSPLQEAAAAGLEQVQECKFFQTQTAEYAERRKVLTDCFDTLGLPYTNPEGSYFILLDISRVEFPDDYTMPSLRVCLEEVKTSTCWFIALEVGVSSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKM3</accession>
    <name>A0ABQ8VKM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39617" checksum="41DD3E8E551A8EA2" modified="2025-10-08" version="1">MAQSSIQTQLRSLDDNHSVFQLSGFIGTLSTLSIAYFSPITRQATWYNFLAFWMLYCLWFLLLFFSGHYRDSQPSLKLCMCQSALIHSASPAASAGTLALVLQLYFSVHSALSRDGIRFQRLWLRLAFALPYVVTLTLMTSVLVMSNAPGTVFIVTQYCSVNQLIPGRLAAGFTVVLIIPILFLNVLIYVCLRKHWSEFRSSRLRNATSMIIRATMFSICGVFAFFLLSVGIIFFTIIFPKRPGETEEDEVARLSKIYEVLNVILGLFPVFVVVIFGTQRDILRRLLFWQDQISSSRTQEYPIPEISLELSISHPGQGEGDPGFVSPLHSSSQIDYSEAHTATGLVDDFQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLG6</accession>
    <name>A0ABQ8VLG6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Nicotinamide-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="12">2.7.7.1</ecNumber>
            <ecNumber evidence="12">2.7.7.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_823750</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>beta-nicotinamide D-ribonucleotide + ATP + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>nicotinate beta-D-ribonucleotide + ATP + H(+) = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the eukaryotic NMN adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.1" evidence="12"/>
    <dbReference type="EC" id="2.7.7.18" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09286">
        <property type="entry name" value="NMNAT_Eukarya"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051182">
        <property type="entry name" value="Euk_NMN_adenylyltrnsfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045094">
        <property type="entry name" value="NMNAT_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00482">
        <property type="entry name" value="nicotinate (nicotinamide) nucleotide adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039:SF0">
        <property type="entry name" value="NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-0520">NAD</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 12" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="14">
        <location>
            <begin position="38"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4497239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="31514" checksum="9C8B817AF9D2969E" modified="2025-10-08" version="1">MATTNSQQKFTNPSNYSFPHDRLNRVLRDPSKIPLVLVACGSFSPVTYLHLRMFEMAKDYVRQNTNYEIVGGYLSPVSDMYKKAGLLSANHRVEMCTIAADDISTPWLMVDPWEAFQSYQRTAVVLDHFDHELNTVLGGVQTEDGEHRNVQVMLLAGSDLISTMSEPGVWSHEDLDHILGRYGCFIIERAGTDVDQAIDSLARWRHNIHIISQLIQNDVSSTKVRLFLRRGLSVRYLLPSRVVDYIDENNLYIDEAAAAEKEKEREQQQYKKESCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLT7</accession>
    <name>A0ABQ8VLT7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="23751" checksum="FFA89F69AB1D6938" modified="2025-10-08" version="1">MEQHVELVVLQTEAAVDEQDDAQIEELLSSFYFDNSVTRQSAGEGSRHGEHLHPIYEEQEEDGIFYDLYGTVEEELPCSICESSDEDNENDSEVSSQYGPKELPPNITQNPSSFWPVIEEDDEAPDAERITFSAKLSSSRSRSNIILEKDEENKNNKEWEDRGRSRAVPARLEQDGRREWIDDQDSIYGREYERSFGKVTEFNFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM34</accession>
    <name>A0ABQ8VM34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_822262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="72"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="33539" checksum="271F1F8A051AA0FA" modified="2025-10-08" version="1">MHASSSFQYRSTASSSYSSSSSHHYSNTRYNSFHGPKQRVLGNWQAGNVAPAWRSSAQGQSQSLRRQQAAGSKILLSQLPLDVGEKEVEELFKKTVGPLKESFIIHNNQGRSKGMAVVVFQRPGDAMIAREKYDGKFVDGRRPIRIELVSDGPAIPTGPSSSSSVPPAPLSLIDRLAKATTPNLSTRNFQKPPTHPNHQLPRQAAAAASIAAAGRPKPFFQSTSIYSTSNPSTSYNSSHVTGPTTSISKRRTKKGPKRLKKQNVHIQFPKFTSGHVTKLAKSKEELDLEMENYRAEADVDFEDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VME2</accession>
    <name>A0ABQ8VME2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_208925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="343" mass="37893" checksum="76D48831576A76A9" modified="2025-10-08" version="1">MLLCISTESIPESPLSLLSQQFLWNMAAQADYPRESGERSLFSSPVPLPACNTQELRDDSIMRSHDSDEVYDKLEAQVITIRTVSPGFQDGVNFLRDHVDDSCPPSLFHHTYMGPSDFVLPRLGTDMGAGAGGADTLGNVDFRGSLPFTPSTPSWTSDPYGGCPLQSVNPFIYTPPVPSNPCSPIGYSYPLAPLPTSAPIYNKYPPPQEFGPIDVSGPLYPYHIATTYAAVDYKTYEAQTIQHDPGFAQNYHYSDQDLGLDLRAQTMDSDLSSGMSLDFVKCETLVKQTQRSWLEDLLGAVLSYGLFSLGVMMLFLGLLYLYDADLQYKTLLEEMETFHAELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMR3</accession>
    <name>A0ABQ8VMR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_879427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="925" mass="100977" checksum="6B91134C4247C7F1" modified="2025-10-08" version="1">MAAPFSRLQLAAALLEYDNDPSDPSAPYRSAHESAIFAHLRRNPARPQVSQRKSDYLGVPLPSETESVLDGKRKSRGSTIGPLRNPFGADDHFEEEAEEQEVQEEAGEMDLDLTSWGLDAFMSKDKSGKGKGKAKSLPSAQPLSAVQAHFPKTNDVLGEVHRRPRTTRSMSVGNYDFLSPAEEVRRKSIGSPLDLSAMEIPASFQRPVASTSQSLDYDSLAYDGLALEEPHPAMGSIPFPTTSVRSPSPMTLDHRRTYSTASFESKMAMSAPRLRTTSNGTMEPTDDNPFTIAPPSRASRFDPKAAAHARTVSNASLGSRMLLENDGASVMTGRPPLESRYSTTMELLRPKVLVMPSPLQSANAPPPSPKGRDGFTLADAPPMPPGARTLMRTPNIGSSTVPVPSNSFTPNPRLNLSLSQLTFRNNLTVGGQRDIAYNDIDGDLPRALEDGEQAKLSTTPTMEMEIILPIPSENATGPHRPAGKLYGKSLIDDLENRKAGMKSKQRVFRGDDRPSMMARTPIARSSTLIDPATLQDHPVNMRASSFEPTSGVARRNSRNTGPLLNFDDDGKVPTVAVNKGPPNRSVFGVDTLWEREMVKLREIEAQEAFERERQQAIEETEALKNGGKKKKKKKGKKGQDSELASPVPDILPSVAGRSVLEDTPAESVVSSGPPVLPTIPAIRGPPPVIDDEVSDSEESTGGRAAQSPQAEGWYADSDEEKDGPRRITGIGVRYPQKQTPRPQIHATEDDSEEDLPLAATIGRAIERTSRLAPPESDSDDEKPLSTLIAKPSLPSINFDNLSPLNAEPDTRDDDDEPLGIRASRIMPNPNADGEDDDRPLAFHPEQQRRTQYQMMAQHQMMMNSMQMQNSMFFNPSMSGFFPPPMVMPPPMVPAPIPIPSPPPVHDAAKFGRVDRWRHDVATEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNA0</accession>
    <name>A0ABQ8VNA0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal RNA methyltransferase FtsJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="832" mass="93717" checksum="1C025D939DDE549B" modified="2025-10-08" version="1">MANSPYSGYNPNLNLNIPYSSYDGGRGYGFGHCPGPYSDSKPENPYEIQEQEEAVVGPHSSPHPENPANNSGHRQHPLGRSSQDSRVYNPSSESRSSFAFASLGPTRPEQVSSKRERPHPHHFPQTSPTNNHLNQFKQSRNSRNDSTSISHVSNRHSRFSNRYHHHDGQPKWDHSEFPGRRQLEVPNERIAGTPRGSGYFDNDQIHRDGSGVLVRPWQSVEANAKLRSRSGSSSSSLGSAKCNKPLLGHHHRHSPSNRVVVPSSYNRQQELVHWDEALNRRSEVAWWECRDSKMEMGGSNWNLMQTETLTRTSTLTEQLIACGAEELQEIFEIWEESQANARKEGTIPRLVFQRESEQRGQGGRERGRREERDRHGNQDKQKGFSQRRQLLRDDDKLPKSNSRVNRYGSLGVQVSDEDSPQVFQEIVSRFSKIFRGPHIDDEGYYFLDVGCRPGGFASFILQNNAFAMGVGISPLPQESVFASETVKLEEGVLERGIPLQLERERAHEEYYARHQKHYAPFTRSSNSRFKLYFLDMAKIDLRRPGEKNRRGLFNSWSGYGNEESFQGGLGYGSSEAIAAANFPSELLDLKRPPQELLFGFKQGPDSNRHTMAGASSRKFNLVILDDYTSSFSLSGDLHLIAQLLLGFQSLTQSQSGGGTLVVRLRHPESVITAKILYMLDTLSSTVAAVKPRGTLGDAEDPGCFYVIAQNVGGGPHGHKVGEVVEELRKLWWKLVMRVVRWKSLVKSVGSDVKVEGGGVEGEIEMGETGEIECNQRGLSPECGLKEEDFDFIIYTDELKGPKSDYLVRLVALGKIVWTRQLEMILMARENRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNL6</accession>
    <name>A0ABQ8VNL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_917010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046810704" evidence="2">
        <location>
            <begin position="20"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="127" mass="14812" checksum="6031FBB6F1285367" modified="2025-10-08" version="1">MRIQSILSLFFVFAVAANALPAVELRSDTVSMAREEEPEVIELERYSPEPQRANSPDWRREPQRGNAPDWRRDPQRGNAPDWKREPQRGNAPDWKREPQRGNAPDWKREPQRGNAPDWKREAESNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP81</accession>
    <name>A0ABQ8VP81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bola-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_757782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230:SF7">
        <property type="entry name" value="BOLA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="108" mass="11812" checksum="0D2CA825D85DEBB7" modified="2025-10-08" version="1">MATASPSLGPIESVIRSKLLSSLQPAALVIHNDSYQHRHHAPMRAQDGGSGETHFSLEIVSDEFKGKTTMQRHRMIYSLLSEELDQGLHSLSLKTKTRAEAGIDTAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPQ3</accession>
    <name>A0ABQ8VPQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3074 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="1">
        <location>
            <begin position="64"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="240" mass="26991" checksum="F715D712421D058C" modified="2025-10-08" version="1">MSDHSEIKLTIKPLKPTDIPSEETIFTTADGLIESCTSWKQGKTYHKVVKTYSRGKGPEDGAPWHCRISVHKSEEATFDQMWAKLGKDKPTNEMQFIPDIHKVTKLKEISSTQSIWSLYYKFPPPVSPRVFTELQVTRLSEVKPRTGIIISIPIDLSSPEDAELAKMEEKGVKGRYVSIERITELEDGSTEWRMATSSSPGGSLPSWLVEGTMAGKISEDVPHFMKWLHSLPKTEATAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQZ4</accession>
    <name>A0ABQ8VQZ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_817724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="729"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="779"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="995" mass="110263" checksum="695CD3ECE53FBADA" modified="2025-10-08" version="1">MWCCGFGLNHRVKISISSLLNPVTRNKDRSQIGDDGRTINWRNINANFRHPHRKPKARMIPVVDSTPFEIPTVSMKFLSRLSCEEAELSRYTLIAAYISCKLVSLVKFQRPLFKRAFVLQEIHRRIYYVLCDIGCSSKLALSSVLYMLRIFPDGIPYSGIRDHNCVHLVVRLFLLGFQLGIAWFHDACCTSKTWSKLMGLTKKNVLRLEQAALQVLGYTLFISPSAWNGFMEQIHEDCPLFLYPGDFENLRQLVRSSRVPVHIAGPEQRPRELAAIGTISQAEIEYHRLRISECAIRGKITVFPNQDTESSRIEVGTEEDYLFDVFDAAEELLLEELVESDQLLPLWPRFLPSTSTNADSKQSSTSLLPPQSYPSSSTRSSPPAPGTCLSPVIKIEEVEVELVWPSSPHNAVSVRDQRSEHPARRESLRELSASSCSAEPHPNSKPVLFSSTNSIAVAGRQSILAHSPTESFNASHSDSRYAVSQGISDMSPNSIIMHSTALPPPSRKGQSIPETEPGSGRSRYKRFETPASPGEYHKISQEVADMLVDLETNSGVFSPSGRFPALASPVHHNTSQGVMEISLDSGVLQSTPLPTNVPSRTDARSPTTEYRSPGQFQSPDLSSQKRDETLTTDLDAPQLDLVTLPETRSSKQNTFFSSTSGAQLVNEDQVSSVPQTPPARLQSTVELSLFSLSPLSPLPSIYDDSDCEAEDDMAQPDELYRSYTGAHLDVQAGRSGPQVRFRTPDEGTQIEEEEDEGEEEVHYCDCSEYEDDGYDSDSEGSGYSHVSSYSSSTPTFDSPVSPHLSQLFSLSSLSPLSTTYNSDVEIDDAEEIDEEDRDSEDNFEDDSDVDSDCSYASSTSATSAFNPSVSPPPFKIPDTYDRETGLWIIPSPKSTEEELGSPGSRHLHQEERPFDFTSAAFTPDIKDEFYSMSHYGPIDLGQGGFADGGERAPSPHPLDLEAELIHREFLSFPPRDRLSSPAVVRINSMVQGALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR19</accession>
    <name>A0ABQ8VR19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_864381</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="484" mass="54969" checksum="4E68C58A1F82E66D" modified="2025-10-08" version="1">MAIFPSVSLFLLAVGLALLTILTRRKIKESYIEFRAIAYSYDLMSSSFRPGQNTYHFTILGNPVVGIRGQEARKVFFNERSFSTSEGYKVFSKAAPVPELAKTLLSAEEGHGLHFKKQLEILVNKNRLADIIATMLGDMQRLTATWNNKGSMDPFDKINDITFHVTAHMITSNDFVSDSVNFSRFQTHFFTQLKNNTPAMIFLPWFYRKSQREKEIAITSLFTTLTGYIEAREKDKFSPSEPIDLLLDHGLNSQEIIQFILGFLFGGVYNATKAISWVLIYISMHSQWKMAIRSEVEDVLSKHSFDISKPLHSRLSEVPLEAWEESLPTLDLVISETFRLVMNQTVLRRNIGEDVEIPGGQGHVPSGAFVAYSNADAHLEPEIYDDPWSFKPDRFEHGKQKVLSNDFLGWGAGRHRCVGLGIAKLTIKTIVCLFVMTYDYDITRTKRKSNPTIPIPDHNKVNEARPKGEVITLNYQRIEQSAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRC8</accession>
    <name>A0ABQ8VRC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein serine/threonine phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_823462</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF837">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="46"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="37831" checksum="E90F38A375371332" modified="2025-10-08" version="1">MSRSQMRSNGQKDPAQNAYSEPITRTSGSDSFGVLNRIPTQYNSYQIGVHEAQGMRPTMEDTHAFIVDFDSVRGQGYFGVFDGHGNKCVSEWCGQEFHKIFLNCIHKNPTLNGLDVLKKSFLEADEVLGKMSEGSDELADSGSTAVVAFLRIEDSDGSQNFPHTDLPEHGKVKVPPQDARRVFYCGNVGDARGVMCRNGTATRLTHDHKPSDSDEQARIRGAGGIVLRGRVFGTLAVSRSLGDHMRYESLKLKDLVIGTPYLSRTELKQNDEFCIIACDGLWDIISDQDAVDLARTVDDAEKASRMLVEYALKNDNMISRDNVTVMVIRFTNTTLVDHSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS44</accession>
    <name>A0ABQ8VS44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatases II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_864329</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="577"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="914"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="783"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="888"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="972"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="797"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="909"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="989"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1097" mass="121138" checksum="E0FFD3BC95D4202E" modified="2025-10-08" version="1">MVSNSIIQLIKSEDREPSTTIRNTIRHLINKVTSLEQASSILDECASAATNYHYTLSNLIQWKSTSDDNGQSLLFQKVLQTDVNDEVSLSILSLIMIYAVSEKRDVLPIADIRRACMIKDDQPLFEFVRNTELYRKFAKDRDAIYLGSTGLQDTVEVQPRTPNSLRVSSSNRHQAAFTAILTIPMFQMRMRGLNEVKLEFIAQDLIPSVAKGRMWCLTFRKAIHDPQSSKKKKSFSLWRRTRMNTESAADNWQIGLSLTDQSESTPVQATITFLPSTWSTVATALRGGLKDSQLKNKDEVEIELSTKPGERLVSEPDSARIESRVKAVKGQTQGIYASLDSGILSSSGSIFIEEDGSLIVILEAILAMTVQPSKQKSVKKVQKMDEPLVDDDIASCLIWNGHLQTAVSRAFVIWRNQTFFGRSSKDFLTGEDKEQQTVCMRQLSLLRPHLHTTATRYCAWVSMPLKAKAKSSLSNYDLEDLLPRWLQTAYTTSHIQSALTTLDEREDARVHLRAESIESVRSKDANQHLSVDAVQPGGAGKIKAKSKAAAEAISNHLHSSDSTFDSSESINFYSIASGTLPVNRQRNRYMDVLPYDRTRVKIKVPHFDNPGSAHDHLSGDDESEGLYLNANWVQEKYGKKWWIASQAPLRNTAYTFLSLLLEDMYPPSLSHSATSTSNPSVPAPKSHINESHHSRPRTVVQLTQNVESGRRKAHPYFPDVVGQTMIIVPDITDYPSSSPTSTSASQLSSSKLKVTLVAQEEIREACCVKSIIEVRPFLDAVVDDEDSDKDSDDLPLRPRSSSSSVPPIPSSSIADSDSDSDHYGDSYDSSTSSSVHRKPKSTRSKTYPAIRFTHLLFVAWPDHSVPSPSDRAALFEFVRLVDRVNRQMPFDDSDSGSSQTTHIRPGETSSKDAKDKMKIISKDSKTVSHDQTGGSTEEKDVDLDPPIIVGCSAGIGRTGSFIAMNSLLRHAGFLPPPGDPQHPSSSPSSPLPSPHLRPPPTQSSQATSLPTTSSQSSTAPTSTTTPPLDASTASYNSHIPVVGPLGPLPTSLSADLVSQEIDSLREQRAGMVQRPEQAVLVYEMMVGAYVERGELKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS71</accession>
    <name>A0ABQ8VS71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Calreticulin family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_754726</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the calreticulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF1">
        <property type="entry name" value="CALNEXIN 14D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045011141" evidence="8">
        <location>
            <begin position="21"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="225"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="501"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="506"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="539" mass="59763" checksum="94C505268D898C8D" modified="2025-10-08" version="1">MRSVALTVVALAASGALAQAEDAKPTFTPTEIKAPFIEQFTEDWSERWTPSEATKKTPVGGETFSYVGEWKVEEPLIQIIEGDVGLVAKSKAAHHAISAPFAEPVDFKEKPLVVQYEVKYQKGGNCGGGYLKLLEDGFQTSGKEFSDTTPWVIMFGPDLTCPGTKIHFIFRHQNPKTGVFEEKHLKASPKPSIEKLAGLYTLIVNPDNTYEILINNESLKSGNLLEDFDPAVNPPAEIDDPEDKKPEDWVDTKRISDPDASKPEDWDEEAPYEIVDTEAEKPEGWLDDEPLIIPDPDAEKPEEWDDEEDGDWIAPTVSNPKCAEAPGCGEWKPPMKANPAYKGKWYAPMIDNPAYKGEWAPRKIANPDFFEDLTPVRSLSKIGGVGIELWTMTEDILFDNIYVGHSTDDAKALATETFDIKKSLEKAKKATDDDEDEEEESFREDPIGFIRSKIFTFIDLLKLDPLLAFKTHPETGVALVTALLTLFGMFGVVTGVVGSQQKPVTKKVDAPKSDEKKKTEAAPVSDEKKDEGLKKRAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSI4</accession>
    <name>A0ABQ8VSI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BAR-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_815346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="15"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="369"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="288"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="428" mass="47657" checksum="AEFFD69C714F658C" modified="2025-10-08" version="1">MKGFVKSVKRTPFMVTSKVGMSKKSNDPEFDDYQRHFSSMEQAVEKLLKDTKAFTDAVNHLFTSGAGYASHFSVIFHPIAGEYDLLGKHPDAAHTIKSVEKYETAMEELRSAVAPELELIESRIVGPTKEFQSVMKTIRKTITKRDHKLVDYDRFNNSLTKLRDKKEKSLSDEKNLFKLEQDFEMATNEYDYINTALKQDLPRFMTLSTQFIDPLFHSFFYMQLNIFYILLEKMNNFSEEAKYDISNLPGNEITSNYESQRSDAWSQIEELNITKRIISTSKFVQSNRAAAGPGVSRATSSTSSLASSRSPPPSGFKKPPPPPFTASHAAPPPPYTPSNGPGSAAASAAATKKAPPPPPPLKPKPKLAPKPQFVVALYDFAAQAEGDLSFNSGDRIEIVEKTASAEDWWTGKLNGIQGVFPGNYVQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT13</accession>
    <name>A0ABQ8VT13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Oxidoreductase FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_817169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815:SF2">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00410">
        <property type="entry name" value="PHEHYDRXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="496"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="626" mass="69044" checksum="C741C96A5BD11D60" modified="2025-10-08" version="1">MALNGWHIGELSIRQKMKFTEDPSLDGMYTWISEEIDPGHAQFHSECHFLPVTTVDSDGRPWSSILAPREGRPGSSFIRYIGGSRLRVSARIWDGEPILRTGKDNMLIAGIGIHFPTRRRNKIAGFVSRYERSRDGDDCVVLEITINETIGNCPKYINLRHLSPHPNTYPKVMTERLHLQKDDRLPAELIDFILASDTVFLGTTYVALEKDAALFPSHLGMNQRGGRKGFIRVSLKDQRTLVLPDFSGNRILTSLGNIEASSLASFTFVDFESGAILYLTGEAKNLVGEDAQRIMPLHTQMALTTLFVTGYIFVLDALPVRQTVGTHAEQSPYSPPLRFLAEEAGGRVISPNPNQTVLLSRIDMHSSSIATFWFQSSVPLTIIPGQAAILSFADLLGKPKYAHMAPSNPKSLNDDRVRTWTVSDSSTHEFALTVREIPGGVVTGALLNLARALAKSRPELLTNASDLEIRLGLVGFSGSFCLPSPAKDSEVKLLWIAGGIGFTPFLRMLKALKEDNSGCRWDIHMVFSTRDPDVLLPLLMKAADSTGETVKFILDLFTSRKVTAMAGSIDDVRIHSERVDSKYLRSTDLSRKIYLCGPKPFEAAVLGGLANSSISAHQVTVEGFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT92</accession>
    <name>A0ABQ8VT92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6697 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_88416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046520">
        <property type="entry name" value="DUF6697"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20411">
        <property type="entry name" value="DUF6697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6697" evidence="1">
        <location>
            <begin position="51"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="19300" checksum="549C809ECC4342F5" modified="2025-10-08" version="1">MNHSASSLTQARDSSLNFQTSLRMYIESLLASYPRYDPEFKPDSRRNPVRVRRDLLNNAYGMGTQQMLAQINPARNPLPSGALSRRERRIMFPNLDRNPDLPRQPGDSGVLFTARPEGEFTLEGCSVFVKKESKNALWDYMGEYKIFPKGKIGGRGNGRGWYEQLPSKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTW0</accession>
    <name>A0ABQ8VTW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GTP cyclohydrolase N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_754916</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="7">
        <location>
            <begin position="70"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="6">
        <location>
            <begin position="324"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="514" mass="56853" checksum="390BD7F969498044" modified="2025-10-08" version="1">MSTTQVDTAVLGQILAQLESLQMTQQAMQVKLNNLSTPSSPPPVETKTLPNGNTTTPTNPTREKSLYPGRVLLTTYPSQHSITPYPLKWGASTPLLRGPIICSRLPSSLPFRNALGAHSGSYSIYRALSIAMGTLDPNYKPEYGMTEPPVEIRENPAWYDAKKIVSMDPWGHLVPSVFEREGREKEKGGLGLDIRPSISVTKAHIKLKEIDEAVKRGEIVIDGKIVLGSEPLRREDGSLVEGIDAGVEVNVSKAAVDPIWYLPGVAERFGIAESLLRRALFEDTGGMYPELITRPDINVFLPPIGGLTVYIFGNPAHIHDPSRMITVRVHDECNGSDVFGSDICTCKPYLTYAMEECIRTAQGRHPDQTDGSPGVGVVVYFRKEGRALGEVTKYLVYNLRKRTGDSASSYFRSTELVAGVKDMRFQALMPDVLHWLGISRIDNMVSMSDMKYDAIVGSGIEIRKRYDIPSYLIPPDSRVEIDAKIASGYFTKGKKVTQEELKNTVGRAWEEVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUC8</accession>
    <name>A0ABQ8VUC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Supernatant protein factor C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_893212</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045396580" evidence="10">
        <location>
            <begin position="27"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="36"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="202" mass="22910" checksum="5724913B8B730ED3" modified="2025-10-08" version="1">MPPSFLQRLVAGWLAILLALQYTAYAHMIDVPAGKKECFFEDLHKQDKMTVTYQVGGGGHLDIDFWLADPEGRLLGKQVKQSTGTLSITAEKNGRFEYCFSNQMSAIADKIVSFNVHGIIYVGEDDVVAPIEREIRLLAHGLAAVKDEQEYIVVREKTHRNTAESTNDRVKWWSVLQAVVLFAVVGWQVYYLKSFFEVKRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUF0</accession>
    <name>A0ABQ8VUF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Glycosyltransferase family 31 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_754285</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF333">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 31 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="82003" checksum="B7756CA2FA650862" modified="2025-10-08" version="1">MSRFQSRRSHFLLPPSPVPSGHSSVASSASSTPIPSRSGSPLPQFLVNSRPVLSTTSDTDSDPTTATPLRNRNLWRQERRSWWQISRRSRRRHGRTWRFLNRWAKRIVRHPLFPRQPITIVLSLILLSLFAILLTLFLIYILNPDKDPLPWRAYCSMPSMNSPPDPTNPSLYHDPFHNYSIGMSAPAFPHDELDTLPPAGLFVGVFSTDSAFERRALVRSTWASHPRSREGAGDGDDGVGTSRTIVRFILGQPRKDWERRIQLEMEEYHDIIILPVAENMNAGKSHTYFSWASINAWVPPVYMKTPVPPPLFSYSNASKPPPPLASHDPSDAWQDLSSPQPQAWVRPDFVVKVDDDAFVMLAELEARLRLEMHAKPPADGSSSQRNAIHRRSDTPPRHNNGSYRKLLSVQTNAYSTFQDQDPLIYWGYLVTNRLHRFMAGELYALSWSLVDWVARDPSVKELTRGAEDKQTAKWMKMHPQAEKVRWISERCWIYDHPRAGTVYGHGFLFPSEVRRVRKSMSSALKHLLHFGASSSLTSSLSWDTETQAISLPSSPDIEQFDSNELLTPYGGTPASWAQSSVSTFHVRYTPPVSDLGTLESIEALVEGSEMSSLRPDTTSSLSTTSTQDAVSRAWANREGRNARYEGKRVGGTIVVHFIKQNTWFLETALALLEGDDYTQAESQKQDILEDCDSDETQNIFDGQRTIGSLDLPFATYAETVRYGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUR4</accession>
    <name>A0ABQ8VUR4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_811774</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343:SF10">
        <property type="entry name" value="RNA-BINDING REGION RNP-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="236" mass="25597" checksum="65AFDA5335D33453" modified="2025-10-08" version="1">MSTYNVTVSGISPTTTETHLHDFFSFCGKIASIDHKGTEAAVNFEKPSAAKTALMLNGGSLDGATLTVTSDTVHPDEHEDSKDEHIDQTDKPRAGIAAEYLARGYTLSDSILQQAIEMDKQRGISKKFLSYFNSLDTGIGSRALGPDKTISGKLQETLAAATQQAKTVDEQKGVSKTAHEYYTKALGSPFGKKVFEFYTSTSKQVLDIHEEAKRIHSTHKATTTHPETPVTAEKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVE5</accession>
    <name>A0ABQ8VVE5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_751659</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>melleolide F + FADH2 + chloride + O2 = 6'-chloromelleolide F + FAD + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67160"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:167712"/>
            <dbReference type="ChEBI" id="CHEBI:167713"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:67161"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin-dependent halogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050816">
        <property type="entry name" value="Flavin-dep_Halogenase_NPB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747">
        <property type="entry name" value="FAD-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="603" mass="68878" checksum="ED7815CFD4D87EB2" modified="2025-10-08" version="1">MTIDDLHYFTQLRATHPELTDSMLLNSNNLSRFSTEPDVVVAGAGILGLCYAIHLKNISPHLNIAIYKKNRAPVQKIGESTLSSFSRFTTGAVMPQDYFFRLFGLKDGLQFYCIDREGVEVTSEDIGGLDLSFQLDRRMSELFFTMWAQRIGINVYHGVEVDFDSTHHFNTPQVKLKNFPKPGVTDVDAKIVCDASGFSRKLTSKFGNKELLDGWNCDAYWAYFKEKEGGKAETRLDHWDYPATKHMCFPEGWGWFIKLISWHHAPLANLMDLVAYIINKAKSGVPANAIPPTKILSEMFNCPFESITSIGWAVRNDHEFPDNLEEYGGGEGERKFNYFKVLYPTLNKLMNGVYELLPKYYGNQTYFVRKSMTYRSPVVAGEGWFAIGNSAGFTNPLISPGINAGIGTSVLAANMSKEILDQPPEHSHVVMKKCAASYQTYSHEFMIPRLHQMNRYWYNSFRDHRLFEVMVPCFWTLGVDDVDSQYVNEFTEEDVYWVIGVGHDDFVDFSGKILDILEPSDGMTVNEEKVEQARALAKQCMDYRKERFPGNEWGKYLRRHDCKLQLVPEKHERMPGGRCFGVRCKSCKVWRHNNMNACPVCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX17</accession>
    <name>A0ABQ8VX17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_362173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="753" mass="83289" checksum="8D990B452FEDAFCB" modified="2025-10-08" version="1">MLAPFGTPQAGAGALDGPLAVDNYKRAVYRPPPARFMVDMLPPAKQGSQYSFGMRITPILRGDRSSVSSSESKLSTKSNVGYEAWRRWEDCLWFQDSLELEYSRLARMKRQRLLAGKGVKKDGFYLQDRASSWESLPPGPEPNSVARDIHDIIPKLTKKGTLFRASQATIEQRHSELTAFVEALFAEDVPTLLAELRADRMVTDFFGYWRRDYDLAMKNDQRSGNKQSKPRSSITSSVLSSYFSSGDNHTDTESVQSRSSLSTSPSSPSFRASRISVSTEAYQYTRAAKSKEKLKKEEFPTRRHTTSSSTSSSGSSSNSRHSMDSIASTIPGIREDVPLTFDHNPQVESQKDRFLQSLPEDAELPIHSDSESIPPSVRRPKKRSSKDTLYRRSARIFTAPPNINDIVDGLRTPTAAQWSGTRGIRDSWQTTGSATTYLEGLNIAIPDSPAHIYHSSRLSIGSIATFMTDSSADAIIPRNRPPSISTRRSSFMRKSRPLSIYTVTDDGPWSDGDEDLLDSCIFDAFPMPAHLFPFQENNKTGPHESRSASSESRPETPLGHLPIIPTSPLHIELPDERLQSIPEDVQSVTSRLSSLSETCFTPVPPSPTSSTTSTEFSSFTAASRISVSTTLSTSTAVTSVLSGNLTIKAAHNQSIILLRTSRETEFAEVRQRIYDKFLAQEKITLTEAFAIAFVLQDPCESRSSKGKGRARSNSLGGGSSQMILVTNQNDWDRALATTESSKITVRVLDTFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXB9</accession>
    <name>A0ABQ8VXB9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_282286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="23781" checksum="EE89886625AB555E" modified="2025-10-08" version="1">MFAFHSAYCGIYIAVSVFPADAMPATRTVTLFEAQFPSNSLSNDIPTPPSTPTLVQSFSILGTTTRNGNTMTVYGEDIINSEYVEGHAVTTVDGSTSYTWTTGTLSTTDTAHEIYEVGTTAVGFIFNNDSAIGVEPLIHIECNFDSGASSGTGVCTEVVQFSGQSTAQSTAWTGSIIPVSTFEVSVSATTTGSATNAAGSVKGGQWSTLFAGTCFVAVLSWLAGVISVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXT5</accession>
    <name>A0ABQ8VXT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_717611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="210" mass="23975" checksum="09CFA63AD6A28EAC" modified="2025-10-08" version="1" fragment="single">GKDMMDGGKERGRAVEFDVVVILKEQMRVVDHTWRDFLVHLRHGMVEERHLKMLRTLVLGDITCLPTDFSKGPWNDASLVTPRHAVREQWNEEALQKHCKNAGSRLYVCKSSNMIQKRSLTLMEKYALALHLGKRKSRKTLPDVVELAVGMKVLVTRNIETDLDITNGARGEIVVIVLDPREPTPEDGTEIVHLQYLPLYVLVQMGRTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXU1</accession>
    <name>A0ABQ8VXU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045469">
        <property type="entry name" value="Nis1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19271">
        <property type="entry name" value="Nis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046025600" evidence="1">
        <location>
            <begin position="21"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="148" mass="15987" checksum="BFA03F26DFFDD42C" modified="2025-10-08" version="1">MRFIFSLLPFLALATSVVHAQNAYIYTPTDMTEVSAGSSFNVTIAQGDSNSSWKNIAIVIALLNCHEYSSTCLGPAEELGTILYSGPFNPQFTTEPGTAELPPHENFTLTVPSDFETGQSQLGVALFDLVGALLFPYLQTFNTTIVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXZ1</accession>
    <name>A0ABQ8VXZ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EXPERA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_806514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19664" checksum="BAF9923A640C7119" modified="2025-10-08" version="1">MAGRWWITAWYILTAPLMLWDAGYCLMRPRSMVGGDLHWIWAFYEFYGNVDHVYGVKAFEDGEGFANAAAVLNVIENFFAVLYLWTTHVCSSELAPLAGYTASAMTLAKTLLYVSQEYFCGFCAIGHNTFPGMLSYWILPNVAWITISGLIMYHLGKDILWSLRLSSERVKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY16</accession>
    <name>A0ABQ8VY16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045868478" evidence="1">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="128" mass="14888" checksum="23BED4F658410893" modified="2025-10-08" version="1">MFKTFYIAVTVVSLLTATYAMPIKERRVVRTFFDDMVGKGFVRQINDTYKYTPEEMNALCSRQLSLSSKDYGHYFQEHLPVKVAEMSGLGKYKGHDRRNLIIKSFPSDKDMRLQATAPWCMAETRLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY59</accession>
    <name>A0ABQ8VY59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD/PDEase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_363150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33594:SF1">
        <property type="entry name" value="HD_PDEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33594">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03035)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="228" mass="25680" checksum="F159AD08B96323DD" modified="2025-10-08" version="1">MYPSTDEKVYIDAAERLMVKVMARYDPSHDAFHVRRVRKTALAIANALPLTPDLLTVELAALLHDVLDKKYVSLEETSDPYAFFLPLFQSAARESNIDIIKDGRARQIALIVDSVSWSTEKKLRATGKWNVWHDECVELHCVQDADRLDAIGAFGILRCAAFSASQNKPLHTPQDDTAAGLSAIQHFSDKLIHIREGMKTQPGKQLAVKRHQLLIHFMQSVNEEYSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYI8</accession>
    <name>A0ABQ8VYI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sas10 C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_807384</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018972">
        <property type="entry name" value="Sas10_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237:SF8">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09368">
        <property type="entry name" value="Sas10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sas10 C-terminal" evidence="6">
        <location>
            <begin position="580"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="447"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="458"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="533"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="656" mass="73644" checksum="88A0F7C39723C9A0" modified="2025-10-08" version="1">MPRRPSKKLKTAGKPRNTNRPDAKINKWNDRSDIPMDEEDQFHASRDQILLNEEEEDDDGAIYDDEVFALQMEDEESEEDEESEAMEENDNQSSWAAPKAARLKQKASAKGKEKGKESQIESSDDDDEEEEETWGLGKAAYYSSNAAQIESDDDEALQLEEQEAKRLQAKARDDMNDEDFGLEDSIEANVIGGSDHLDEASVPVQPVLQDKSSILRHLQKTDPECLALAGDWTDSATTLMKTKQKLEKLEAEGGSKNSFSLGMMHLHYQTLLTYTTTLAFYLYLRASQKYAQKPELLRSHPVMQRLLKLKQSLITLEDLNFAVSDDDDLGDDEEEENEEDDIMQDARQLWDREHSNEDADEDVDSDELDQLLADARSITNSNSNRVIIQPKAPALTHPPKKKRKTGSESEKSSLSMFDLVEPEFVSSKTTSSTSPYAAADAFGEATSLQHADAADKSARRKTLRFHTSRIESANARRSNARSNALGGDDDIPYRERKKEREERLAREAAARVRTQGGADLDDTEPEPRKPDDSDGDGDEEMEDANGYYDLVKKQVKEKKERKKAEYEASRADRFVEEASNGPRSLTRAILANKGLTPHRPKSVRNPRVKKKINFAKAQRKVASQKAVYKGGVNATGGRYEGEKSGISKVVKSVRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYT7</accession>
    <name>A0ABQ8VYT7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial proton/calcium exchanger protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Leucine zipper-EF-hand-containing transmembrane protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_748177</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LETM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="15">
        <location>
            <begin position="195"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="576"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="50"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4501543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="642" mass="72347" checksum="0266C4F930597CE0" modified="2025-10-08" version="1">MSLIWLPRPTPAFLSRSHSRLQYVLRSYSVFLLRTPSSLHPSVFNVHPSRRFQSSQPLGSKPSGPTVPVDPHTSAEVKPSPPATAESPKGPLLIRAWKKVKHEAAHYWHGSKLLVSEVRISARLQWKILHGEQLTRRERRQLKRTTQDLLRLVPFAVFVIVPFMELLLPVALKLFPNMLPSTFEDKFAAEEKQRKLLRSRLEMAKFLQETLRESPLKANAHIIGSDAFKAFFLKVRSTGESPSASDIINVARLFDDDLTLDNLSRPQLVSMCRYMDLNAFGTDNFLRGALRSRLLTLRRDDQLIDAEGVDSLSTSELQGACQSRGIRTSGVSPARLREELSTWINLHLHNRVSGVLLVLGRAFNFDRKTGEDEDGKTNVIKSLESVLSGLPDNLLNEAELEVDSDKASYKQKLEVLQQQEELIEDEEEQEQKEEDARRAKREAEEREAQTAQALLPDTELVPESVKAEGDDARMTTEQLKELGEALSILSTRSSVLKERSDLRALMDENLQAEEDPKSPSGALTKRIRTMLTKIDKQLEEYDSRVGSSLQMISQDAQGRIPVQDLQKALAVIKHRPDDEVGQAVIQKLDVDKDGFVELEHVLGLVQEEGLGIVLDDDAQTLIGQGREIKNSKPRKEDIVQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ57</accession>
    <name>A0ABQ8VZ57_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_748714</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate. Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartate 4-semialdehyde + phosphate + NADP(+) = 4-phospho-L-aspartate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:24286"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18130">
        <property type="entry name" value="ASADH_C_arch_fung_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02315">
        <property type="entry name" value="ScASADH_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051823">
        <property type="entry name" value="ASADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006416">
        <property type="entry name" value="PRK08664.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718:SF1">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000148">
        <property type="entry name" value="ASA_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="11">
        <location>
            <begin position="17"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="41739" checksum="35B043A115D6516D" modified="2025-10-08" version="1">MSSKITPNTVSSLKKVRVGVLGATGTVGQRFITLLSEHPWFIIEALGASERSKGKKYREAVKWKQTIPLGGLAADLIVKGCTPEEFKTCQLVFSGLDADVAGDIEYAFRAANIPLFSNAKNYRRDPHVPLIVPLVNPSHFSIIPQQQSLHSPPLSKGFIVTNANCSTTGYVIPLAALEKAFGPIESVLVTTMQAISGAGYPGVPSLDILGNVVPYIGGEEEKIEWETLKILGGITDSENETDKNGAPLKTFDMHQAGGRPALRVSASCNRVPVVDGHMECVSLRFHRRPPPSPQQVREALSVFTPEIQSLGCPSSPRKAIEVFEEPDRPQPRLDVKGTHNGAGVSVGRVRQCQVLDIKFVVLSDNVSIGAATSSIINAEYAVLKGIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZF6</accession>
    <name>A0ABQ8VZF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">RNB-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_748706</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09862">
        <property type="entry name" value="PIN_Rrp44-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033771">
        <property type="entry name" value="Rrp44_CSD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033770">
        <property type="entry name" value="RRP44_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17216">
        <property type="entry name" value="Rrp44_CSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17215">
        <property type="entry name" value="Rrp44_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="PIN" evidence="12">
        <location>
            <begin position="76"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="RNB" evidence="13">
        <location>
            <begin position="520"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="328"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4501763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1001" mass="112247" checksum="4F9AD8A51F1BF109" modified="2025-10-08" version="1">MVEITIRKRPQTEAVITQRKFFKKTARGKVVKVLRERYLRDDVACGIEGCRECSTEISRLLPLSGSLEHDLFPNGHYILPDTNVFLAQMDLIESSLFNPPMILLQTVLEEVRHRSLPLYNRLKALTKSEDKQIWVFYNEYRSETAIVREENETPNDRNDRGIRTAAAWYNTHISLTHTPVRGQKQMPHPTVVLITEDAANRQKAEKSGIVSVSVRRYVETMKDANVLLDLLSAEGSHNIEPTKAAAGRQALYPDYLPTPTLIAGVKAGELHQGHFNPNQYNYLEGSVPVPAFDKPILLVGRENMNRAVQGDIVVIEVFPEKDWKAPADEVVDQEAMQKNDDAEDSGEEGDENDEEVFSKESRVLSGSSNQKPPSERQPTGRIVGIIKRNWRAYVCHIDSTSLTSTLTTSLSTQTVFATPVSRLLPRIRLRTRQAPTLLNQKILVTIDRWDSTSRYPEGHFVRALGQVESKEAEQESLLLEFEVPYRPFGKAILDCLPPEGEQWVVPPKGEFDLQNIWRDRDDLRDVIVCSIDPPGCQDIDDALHAKLLPNGNIEAGVHIADVSHFVLPDNPMDSEAAARGTTVYLVDNRIDMLPSLLGTNLCSLRPFVERLAFSSIWELTADAEIVSVRFTKSVIKSKAAFTYEEAQIRKDDPNLHDELTNSIRLLNSLAIKLKAKRMAAGALNLASPEVKIHLDSAESSDPIDVEQKELRETNSLVEEFMLLANISVARKIEESFPQTAVLRRHLPPPKTNFEKLQDILRKTKGFSLDVSSSGALAASLDECVDAREPAFNTLVRIMATRCMLSAEYFSSGSVAKDTFGHYGLASEIYTHFTSPIRRYADVLVHRQLSAAIGSTPLHATLHSKSHVERVLDVVNRRHRMAQMAGRASVEFYVGLALKARGEQARARGEPDVREDAYVIRTFRNGVGVFVSKLGIEGLVTFKRETQFDAENYTITVPGAKEEVKISVFDKVVVRIEVEKDKNTQRGKVKMTLVEPVDSSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W045</accession>
    <name>A0ABQ8W045_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBZ4-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019240">
        <property type="entry name" value="DUF2196"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03833">
        <property type="entry name" value="YwbE family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069:SF1">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09962">
        <property type="entry name" value="DUF2196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="23603" checksum="3EB5697E52F951CB" modified="2025-10-08" version="1">MIQRPRNRQGRKQQNHQNNKQPPARGGGDSQKRSNGSSSHSLSLVPTVRQVIYGAHVSIVLKIDQPTGRQVQGTVAEVLTSGDHPRGIKVKLVDGRVGRVQRMITEAEAKAGSSGLTNLDRNGEPSVTSHLAASSNQSCFRNPFIREESGMNPTPVGFNLGDFFPRDVFLPPEEGAGNCRQDFGRASSDSTTQICPVCYDFEGDEVAVAHHVDFHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DXK2</accession>
    <name>A0A9W9DXK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">39kDa subunit of Ndufa9, NADH ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_534141</name>
        <name evidence="3" type="ORF">C8R41DRAFT_913455</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000006">
        <property type="protein sequence ID" value="KAJ4491261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DXK2"/>
    <dbReference type="OrthoDB" id="275457at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="54"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="369" mass="41046" checksum="D8F252E90EE21580" modified="2023-11-08" version="1">MTASSNLLRIHHAINRQSKRAYHDLITLPSKKPIISQGPPGYSAVTGHVVTVFGCTGFLGRYLVSKLARQGTQVIVPYRDEDEKRHLKPMGDLGQIVPMEWDIRNENQIAECVRHSDIVFNLVGRDYATKSFDFASVQVDGAERIAKIAAQSGVPRFVHVSHLNASATSPSKLYQTKAEGEERVNTAFKGATIIRPGPLYGYEDKLLNNLAIWPIWWKLNDAKTRTRPVHVMDVAQVLANLVHNAQQGRTIALPGPSTLTYEYLLDLVSSLTFQPPSRAPVVPKAVALAVAKAAQAVWWPLLSPDEVVRRYIDDADTPGDWDSVGVTPSEIEQHAIQYVRRYRSAENFSRPNVFPPRPVLVEEEVGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXB2</accession>
    <name>A0ABQ8UXB2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit TIM54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_859505</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000136">
        <property type="protein sequence ID" value="KAJ4464697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021056">
        <property type="entry name" value="Mt_import_IM_translocase_Tim54"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11711">
        <property type="entry name" value="Tim54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="369"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="369"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4464697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="537" mass="60148" checksum="A3186EEF0919B13F" modified="2025-10-08" version="1">MSSSSSQKPKSGFVAALEYTGIPPSLLKRPKLPGRNWLIFFGVTGSLVGAYIYDRRQCRSLREEYIGRVQNLAEEYSWHNGSGPETLGKDAHLAWPRKLTVYAAKWPGDEDYDVAMKYFRRYLKPIFVAAAIDYDMVPGKKHGDVALRIADEIKRKRAEQEYATSSSESVSPGMAMPPQYHAPTQTERESLELAGGTVIIGRATLKEYFSGIVRGWTEPPTVDGRPNWGDDSREEKVRSMLDDSVFDEQDPYTQNVSSSLNTPAPLPISSNAPLPDIPPLPPLLLVPFVNHIGFPQIPYMVLDFFYRRKHVRDGGEAALRAVSGAARELQGPNSTLKSGLTHLAPPPPQGGDLDFALRTESFYRSSLRSPLPSLLDTSPSSTSSESSSLSSTTIPTSESTSVNDINPKSPLGVIQRAREKYYNELPRKLWVAREFARRGGFDEIERPNIGEYGKEDIMSEELTKEWKKAKEAYNSDPSKIPPSEVQLRLERLEKEKIWRRDEEGWEIVRPERGVCWDERLGANGKGALTVFIDPSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXJ5</accession>
    <name>A0ABQ8UXJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_782282</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Cytoplasmic vesicle</location>
            <location evidence="1 13">COPII-coated vesicle membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Endoplasmic reticulum membrane</location>
            <topology evidence="2 13">Peripheral membrane protein</topology>
            <orientation evidence="2 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Golgi apparatus membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000133">
        <property type="protein sequence ID" value="KAJ4464852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01478">
        <property type="entry name" value="Sec23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11287">
        <property type="entry name" value="Sec23_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037550">
        <property type="entry name" value="Sec23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="15">
        <location>
            <begin position="54"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="16">
        <location>
            <begin position="122"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="18">
        <location>
            <begin position="397"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="17">
        <location>
            <begin position="512"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="14">
        <location>
            <begin position="624"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4464852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="764" mass="85214" checksum="77959627D7593A78" modified="2025-10-08" version="1">MLDFEDVEERDGVRLSWNVWPSSRIEATRTVVPISALYTPLKVREDLPPVLYEPVACKPPCRAILNPYCQIDIRAKLWICPFCLTRNAFPPHYKDISNTNLPAELLPKYTTIEYTLSRPAQVPPIFLFVVDTCLDEDDLKALRDALVVSLSLIPPYALVGLVTYGTMTQVHEIGYPECSKSYVFRGGKEYQPKQIQDMLGLSSTNRAAPRPGQPMPPQAFGASRFLLPVQQCEFQLTGILESLTRDPWPVANDKRALRCTGGALSVAIGLLETTYPNTGARIMLFTGGPATEGPGMVVSNELKEPIRSHHDIDRDSAKHYKRAMKFYEGLAKRASNNGHAVDLFAGCLDQVGLLEMKSLPNSTNGVIVLSDSFATSIFKQSFLRIFNKDEQGQLQMGFNATFDVQTTKELKVSGMIGHAISAGKKSGCVGETEIGIGQTSAWKINTLTPRTSAGVYFEVVTPAGQPLQPGSRGLIQFVTHYQHASGQQRLRVTTIARNFAEAGSPNIAASFDQETAAVLMARVAVFKAEVDESPDVLRWVDRMLIRLCQKFADYRKEDPTSFRLTDNFSIYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNEEDVNNSLIMIQPTLMSYTFDTPPQPVLLDSVSIKPDVVLLLDTFFHILIWHGEVVAQWRKQGYQDQEGYENFKELLEAPVQDAQDLLGERTPIPRYIVCDQGGSQARFLLSKLNPSTTHMSATMYGQSSATGSGQAIFTDDVSLQVFMEYLKRLAVGAQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYN2</accession>
    <name>A0ABQ8UYN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Triose-phosphate transporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_780967</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="33"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4466048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="357" mass="39268" checksum="7856F613B1F1AFF9" modified="2025-10-08" version="1">MKSSPNSLLPSPTSHSLPSPSKTSFTDSRPFWLTLYFFFNLGLTLYNKGVLVRFPFPYTLTAIHALFGSLGGAVLARFQVFVPPRLKNNETTVLLAFSVLYAINIVVSNVSLQLVTVPFHQVIRSTTPIFTIIFSALLLGKSSSRWRVITLIPVTVGVGLATYGDYYFTRWGLILTLLGTVLAALKTIFTNVLQSPVPSLTDPTPKSFLSQIYPFSILAQARLHLNSLALLSLLSPLAFVQCVVLAYLTGELDRVRLYSQQEMTGTRLLALALNGCIAFGLNVVSFSANKKVGALGITVAANVKQVLTILCAVMMFHLNITTLNSLGILLTLLGGAWYARVEYMEKQEQQQQRNRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYZ6</accession>
    <name>A0ABQ8UYZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_859616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000138">
        <property type="protein sequence ID" value="KAJ4464584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047363531" evidence="1">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="56" mass="6086" checksum="0435F1092039512A" modified="2025-10-08" version="1">MPRLLATAPFLMSSCLVTTRTAPVSAIRSHNPHRPTSVPPQNIPVTIFSFLNTSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZH1</accession>
    <name>A0ABQ8UZH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phospholipase A-2-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_780399</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015155">
        <property type="entry name" value="PFU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51394">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="181"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="221"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PFU" evidence="6">
        <location>
            <begin position="357"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="7">
        <location>
            <begin position="532"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4466592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="820" mass="89577" checksum="AD74F6A9A1DB9755" modified="2025-10-08" version="1">MPYRLSATLKAHTSDVRAVNSPTNDMILSASRDSTAISWQKSSSHPNFTPETVIRASTRYVNAVAYISPTPDAPKGYVVTGGQDAIINVFSLSSSKEDPDFSLLGHSENVCALDVTPGGTIVSGSWDRTARVWKNFSLAYELKGHELSVWAVLAVDEEQTLTGSADKTIRLWNQHKLISTFRGHQDAVRGLALIPDLGFASCSNDSEIRVWTLGGDLIYSLSGHTSFVYSLSILPSGGIVSGGEDRSVRVWKDGECSQVLVHPAISVWSVSTMPNGDIVSGCSDGVVRVFTEVEDRWASPEDLKAYDDMVASQALPSQQVGDIKKSDLAGTEALNAPGKKPGDTKMIRNGDIVEVYQWDADNTTWQRVGEVVDAVGQGRKQLYQGKEYDYVFDVDIQDGVPPLKLPYNVTENPFTAAQRFLQTNDLPLSYIDQVVNFIEKNTAGVKLGSNEEYVDPFTGASRYRSGGNSVQTTNLGPSTYVDPYTGASRYSGNSAAPSAVPPASSEYMDPFTGASRYSGAPPSNPPTSASPKRIPMAAWTLYKPANVPLMRQKTFEVDGRLRDEISTSSLAMYPQELASLEETFAYLTHITDPKSSNSNLPTPTASNVDAIIQIIQRWPSAALYPVFDLSRLVAAFCPGAFDTPALKSRFIQALITAGEWSSTWNLPLQKSREINLTLALKALANMFQEGTKLDEPWVNEVLSALSLLPYEVLSKVQRTCLATILFNISCTQHSSPLDTPQRQRFFELALQNLKNERADSETVYRTLFAVGNALYTMKSSGNLLEPRQNQVLVKTLPSISQTFGSEARVQDLTGEVTSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZJ8</accession>
    <name>A0ABQ8UZJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_898499</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF43">
        <property type="entry name" value="STEROID 5-ALPHA-REDUCTASE DET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="120"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="205"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="274"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4465480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="35739" checksum="C59AD48F635D1E93" modified="2025-10-08" version="1">MIKLSPHEVRILYDACRKWFTIVSIIVAPALFIINAPFGRFALNGKSILLLDGRKSWIAMEIVSPLMFILSFLKSPLSRGEPVSLEPSLAQYILAAAYLVHYSNRAIISPLRTPSRSQSHIIVPIAGVLFNVLNGSLIGSYLSSPAAFANFSHVRPTFYVGLSLWAIGFAGNIIHDEILLNIRRKAKTKPDGKATRTSNEFAETKKTSEHYAIPYGLLYKYVSYPNYFCEWVEWFGFAFAASPFPINASVLPSPSTFLAFICAPPSLFAPRLTPPWIFLLNELVLMLPRAYKGHLWYKERFGDSYPKERKVVVPFVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZN7</accession>
    <name>A0ABQ8UZN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_54706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="672"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="793"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="987" mass="107138" checksum="C584F60C48DED799" modified="2025-10-08" version="1">MGDSLFLEGRTRSKLTLPEASIELSRSPLKNARLAFRNRSRLELEEGSEARVEDSAEEDEMNLSPKKLGDKRSPSPSASTDWPRLKRFKSSLKGSDLEANIASKPAHSRHLSDSTLLVAKIRRKRSATTSKPKSSSSSTTRRQSPAVLPLQKERARSVPIFPSFRDFPVIDINDIPTSPTRRRPPSWEPKLRITSGSLFPQSQTLESIPDEASEEQEATVGAARGVVAEIFVDAPLPAPPRQTDVLVVPADIHAVPLSPLTPLSETPFFKKATENVNNTEDRFIASGEGQALFRKEERKAASEIEVVVPDKVSRSRLPRPTNATASSSKTNLRGVVPLKATSSRPTALRGQDTNAFDVLMGRTGKMKAKEKKSTEMAETSMHLSGVNVDKATEIGKVTKQKKGSDVKGKGKNSANVEVKSGSTSTIIGKMRPRTKPDVKKLAVPHIFLEDEGEDLPGELSNIGKIPGSPAYPLQPLPTRNSPSPQEFGALPPKSSSPDMEERLIGVDEAILTMDDVEVKGADEIAVERQLAPNDSLPAIDTNVVPRVPSPLFSEPPTTAPSPLFSEPGHREDENSKDGAYDEHVDTTDKPDGTARIYDEPMEIEPHSPSLTTLEVRSSPTLEINSRTRRQKVARPPLPPRTTRSASSKVPTKESTTSGRTKKVPVSRKAGKKAANQAVALADVAPSAVASSSSTDLSGLKEPPADVHISNPQTLPVFTDGEPLSELSDLPEDYLDVELPLKGDGGEDVEMEAPSDTAESRMKPSGDEKNLIRFSPKKKSPRGLKSEAAPEGASASFSVVSPPSPNSTSTAPISVRSTRSSKKSAIPVPITPARPKSSIFKSPTAPGIKPGSAPSSPTKLTKSYSMFSYVPVMPHLINSDTSVLARLDHALAALSKPPPAWEPMRPNTSMGFNRDDPDSSIEFEGGVQIVCWKRERENRYRRLDLVGQAQVRRRLQAPIVTLPTPNPHHICRPPLKYWLSRRCPSSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZS4</accession>
    <name>A0ABQ8UZS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Adenosine kinase</fullName>
            <shortName evidence="10">AK</shortName>
            <ecNumber evidence="4 10">2.7.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Adenosine 5'-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_779801</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>adenosine + ATP = AMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20824"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.20" evidence="4 10"/>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001805">
        <property type="entry name" value="Adenokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769:SF3">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00989">
        <property type="entry name" value="ADENOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="11">
        <location>
            <begin position="39"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4467331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="344" mass="37126" checksum="62D72EB52CC3380D" modified="2025-10-08" version="1">MSYSIFCVGHPLIDMQVREAEDLLAKYKLNANDAVLAGVEHESIYEELVREHQVVYVAGGAAQNTARGAAYVLPPNSVAFAGCVGDDDLAEQLRAVNRHDGVLDVYQVKKGQKTGACAVLISNGHHRSLVTTRRSSNDLDEEHFWSPTVAPLISSAKVIYLEGFLLTFRPEVSISLGKKVSEDGKILVLNLSAPYIPRSYNTQIQEIAPYCDIIISNEAEAEAWAASNGHPDPTNMPAVAKAIALLPKANDTPPRIVIVTHGAHSTTLVSADAPDTPKTYPVQPLKEEEIVDTNAAGDAFSGGFLGAYVSEKSIDVCIQTGHRLAAMCIGQEGPQFKWPKVKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1U1</accession>
    <name>A0ABQ8V1U1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inhibitor of growth protein N-terminal histone-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="650" mass="71216" checksum="63053E943359D953" modified="2025-10-08" version="1">MSSTAHSNFFQRGRINAKDLTRQDPKYILDYAARYDIPKTLAPEEIVDKIFNGRQKFIPILPNHTWALEDDCIVLIERRQPPKFPHYQSLPPNTCPPLGDAFPEPPEDTFSRSPSPTSDKSAEEHPSPRLRLPLVYPPVGLNDQAVPDGWLQQMLEEYQEDHETVVNDLQKLVEEVESVSYETVRVMSKIRKEQADTWRLLDIVKEVCGSELLDKILRDVHATTRFEMNRRTSGSSSQLIPPTAGEDGGKIRSKKFTKNKQIFSMTRGSVLPLNESNVPGPSVQPSDLQTRVSLSTGPSVDASVARKLATAAPHTSAPESFSPITQPTATSDLDNTVNPTIKSPVPARNKRSRPNSSNDTSDDVGSVASRLKRRKASLAVSGDPAPQGNTPTAAPLPVSTSPVLPSVPSDPVDWTISSAQPVQRSDGPFNLWGPMPAHMLRGPATRQTASTSAHVAGSSNNPSITASELPRIEESYNLWTAKFPTPFERRRNPNPDPAESSQPATDSNQSSVGNLLNATSSSSVTNSSLPIASSSRPTTSSSQPIASSTQPTASFSQPTERRRPAPLKRANERLVMNSDGTLELIDIDTPERIAASEELVRDAQRKGHYFTLTTIAEQCAPRYPFLFAGKKEDDYHSICPPSPRAGWGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1V8</accession>
    <name>A0ABQ8V1V8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase delta, subunit 4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_109395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="24940" checksum="C1A27A664A37EC53" modified="2025-10-08" version="1">MPISRRTSSTQSKLNFGTSKSSPAVVGGKKGKHSDRKALELRKVEAEFQDVEGYSSSSSSEHDNIKEANESEPVEHPIAVTTLKRKRSGLGEGKEKKKAGVKNEGQEPQAGPQTLVKSIKERAELRVHDPRWRKVSAQARAVNGHLQLVHAENQNNIHDILRVFDLSYQYGPCYGISRLDRWERAEAMGLNPPPEIHAILSTRQGVEDTQYAQCVFFDQAERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1W3</accession>
    <name>A0ABQ8V1W3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="832" mass="94935" checksum="1209B2D250AA0FC9" modified="2025-10-08" version="1">MPVLSSSPSSTPLVKMDDETEAPMVHGFPLDTLIKFLNQPAASSLFSSYPLFLVRVERGKEISIYRRIAADLLQDVPSPNLLFPPTRTLIAGVYRSRLPGWLYLQVPNMSSANTPLATYLHHVEGFLYERRPSNPSAQKDRTIWHGDMGCVISSDNDDRMKDAGETMRLVLLIPRLPTNARILEDFLKEQKKLQKRLRRSGRGRTSLFPIRPEPALFDIEFTKTFTASVKIQRPQQVGCFDCNDPQSCLPFHRSLYWYLEHLLEARLTTVVLDESDMKKAPPLMDPKLFAMFADSRHPLLNSVATSAMPPPSNWIFEQHDRVRVAHFDGNKQLPLHSNFMRLQDLDGVLEEVLELECVVAFGEFDRERIPKVLLRKSFSVGDCVQTPDQDSVGLVIGDGDKPWSKVVFFHNLSLSFHVNVLREVSEGKAPLSHQDTDAQHGPNLPSGSVNNFAEVSPEAPYISKHEQNSLNHKPLSIEKNANTPAPPWVGFRCICIRHSARKGFHAVVKDVGRDLSLKSGLRVLISYDNPNLPEDWVDYDDLRCQETFRFLDDDSIQKEEKRDSYYHFKSGYQPRYTKYETDVLQEARLANEKADMEAQFKRSAHAELSRAVSHPIPTSADNWMLDPRLKLSLGFLEFNVIIRRGPYALDPPEDIPVYLAYNIDNELQIYLRTDRKQSESVMVPMTDIYEPGAPKTQKIPRTIARLRGLYMIADGEEENPILNENIGKLVRRITYVADDSLEGNDLVVCKVVRVYRLPGRGMNYTEELTTEPLLTVPRRYLVEVEESEYMRQKGNSLVAQIRLKAQPPGQVMQLDLNFSGRRTKKRKPKDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2U1</accession>
    <name>A0ABQ8V2U1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="343" mass="39354" checksum="5913A30B28E14D4D" modified="2025-10-08" version="1">MTERLEIDPAKIPAPNFAKGAYTFMRNALITNTNTPEITTYEHAAQRLKAQLREAETLREQRRQQIADAERLAAVEQQEKEKEKGLGNRFHYKSTHTLYAKKMMTARKYVPLWYFLPEAATEAKERSKDSLDTNHLQFAVEDGDMLSGSTISLVGSHTVRASPNAIPDSRLSWFQVMRAKSAFLDTLRLGAWPNDHISMFAALYINMDMHSELQEQDGDWVMAHYHAEMRLAWYDAMERKEPFDLSVISDRVLAESRREIIKQRQEKSLKGKQTSSIKNHRLIIDTYHFLASLYGMNTSPFQTTTLTDTNATFATYATLMLPEPPMLHKCYSLPPTLTNNLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V370</accession>
    <name>A0ABQ8V370_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_924477</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Self-assembles to form functional amyloid fibrils called rodlets. Self-assembly into fibrillar rodlets occurs spontaneously at hydrophobic:hydrophilic interfaces and the rodlets further associate laterally to form amphipathic monolayers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Secreted</location>
            <location evidence="1 8">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044991068" description="Hydrophobin" evidence="8">
        <location>
            <begin position="19"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4471927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="98" mass="9734" checksum="94EC326F25F20571" modified="2025-10-08" version="1">MRFKITFVTVTITSLAAAISTLPTEPASSCSTGPVQCCQTVESAQSSSAAGILSALGIVLQDLNVIVGLACDPITVIGAGGSSCSAQTVCCEDNSHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V394</accession>
    <name>A0ABQ8V394_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sec63-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_596454</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18021">
        <property type="entry name" value="DEXHc_Brr2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041094">
        <property type="entry name" value="Brr2_helicase_PWI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048863">
        <property type="entry name" value="BRR2_plug"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21188">
        <property type="entry name" value="BRR2_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18149">
        <property type="entry name" value="Helicase_PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="518"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="754"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="1426"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="230"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1684"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2263"/>
            <end position="2285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1684"/>
            <end position="1700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4471946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2285" mass="253769" checksum="1C96E957A99E9964" modified="2025-10-08" version="1">MSSSSNPKPDLSQYNYGAISSLVLTADRSALPRRDKEPDGAPTSLAGRIDVRDMGSRVVREGPGDVGKRKKREERGKEGGGKKKEETKGGGTGTTAFGFSGYTDILDATHQVSGLTYRPKTLETQQVYELLLSEIHAILGGQAQDIVRTAADAVLEILKDSSRGMKDLDKKREMEEFLGAVGEERYGVLVGLGRKITDYYVGGEGGEGGEGGGGRGKGEIDDEVGVAVVFDDEEEEDDGEGFEVRDDDDDEDEESSSSEDERPTVAIEGDDEEIVVGEKPKKQTPKSKKDEVVSPHSIDAFWVQRQISQVYPDPHTSSTKASEVLSILSSTTTSTLRDAENQLMDVFEYSHFDLVRKLLRNRDVVVWCTKLMRSSREERGDVEVAMRERGVGWILRELDGERRLDTSTNDDDGEMEGEKMDVDAGPVTATLRAPKTIDLNAMAFSQGSHLMSNKKCVLPEGSFKRARKGWEEIHVPAVKSRYSTTVGDELVPITALPFWARAAFTVPNLNRVQSKLFPVAFGTDEPILLCAPTGAGKTNVALLTILSELSKHHSPPPDSDPSTTPFTPSSTDFKIIYIAPMKALVQEMVGNFRSRLGPSTPFNLTVGELTGDSQMTKDQMRETQIIVTTPEKWDVVTRKGGSAGGGGGITEGVVKVIIIDEIHLLHDERGPVLESIVARTVRKMESQSNAHVRLIGLSATLPNYTDVAAFLRVDPSIGLFYFDATFRPCALHQQFIGVTEKKAIKRYTLMNEITYEKILDQLDPSTSGGRNQSLVFVHSRKETSKTAAYLRDTALSKDSITSFVNPSSAVREILTTESQSIQNPFLRDLLPFGIGIHHAGMSGTDRATVEDLFSDGSLSVLVCTATLAWGVNLPAHAVIIKGTEVYDPSKGRWTELSGQDVLQMLGRAGRPQFDTYGEGIIITKGEELQYYLSLLNAQLPIESQLLGGGATDSSGTGTLSNALGPGKGSTKIVDALNAEIVLGNIRTLTDAVDWLSYTYLYIRMLASPSLYGVSTDYLLPSDPTLLLKRSDIIHTAASLLDRAGLIKYTRPSSSGSGGGSFLPTDLGRIASHYYISHNSMLTYTRLLRPTHRSLEILRVFAASEEFREIPIRQEEKIELGKLLERVPIPVKEGVEEGGAAKVNVLVQAWVSGLKLEGFALVADMVYIQQSAGRIMRALFEICLKRGWAVPAKACLELCKMVEKRMWGSMTPLRQFKGVPQEVIRKAEGKQFPWYRYFDLSPPEIGELINLQNAGRLVHRLVHSFPKLQLTAQVQPITRSLLRIDLSITPDFIWDPKIHSTSESFWILVTDTSGDLILYHSPFLLLQRYAESHDEHTITFTVPISPSPLPPNYFVEVVSDRWLHAETRLPISFRHLILPDKFPEMTRVLELQPLPLGALHNSEFEAIYRGESGGVETFNKIQTQVFQALYTSDENVFIGAPTGSGKTICAEFALLRLWSSNSKSHPAPSSSSHPKRAVCLLPYQDMVETRVSEWREKFGRVQGGKEILALTGETTADLRVLEKSDVVVCTPAQWDILSRRWRQRKNIQTIALVIADDVHLVGGEPGPTYEIVLSRTRYVEAQTGVRTRIVALGVSLANAQDLGEWIGVKGGAVFNFEPSARPLDMDIHLQSFSIPHFPSMMSAMSKPAYLAITEHAGRKPVIIFVPSRKQCQLTVDEILTHAASDTSSSSSSLTSGTLGADAQQHPDQTERDRADRFLNPDIELADLEKHLEYVSDEGLREVLRHGVGYYHEALSKQDKKVVQRLFESGAVQVLVASKDTAWSLPLSSYMVIIMGVQYFEGKEHRYVDYPVMDVLQMIGKACRPRHDDRSRCVLMCQQTKKEFYKKFLGEGLPIESHLTAVLHDYFMAEIAVKTIENKQDAMDILTWTYFYRRMTQNPNYYNLHNVSHQHLSEHLSELVETTLTDLMNSKCIAIEDESDEVSPLNLGMIAAYYNISYVTVEVYTLSLKERTKLKGLLEVVSSSAEFEAVPIRRHEDVLLRRLYDRLPVKLDSSSVNYESPHFKTFLLLQAHFSRIHLPADLVADQRLVLEKILNLLSACVDVLSSNAWLNALSAMDLAQMCVQAVWERDSPLKQIPHFEAEVIKRCAEAGVESVYDVMDMEDEKRIEVLKMSNAEMQDVAAFVNSYPSLDVAQELIKGEYTAGAPIFLQVTLSRDVDDEDSPEGTDDQTVIAPFYPTKKMPNWWLVVGEPSTRQLLVIKRVTLNKTLTVKLEFTLPKGKHPLKLYVICDSYVGADHDIGLGEIDIAEGEDSDEDSDEEGSDDAMQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V404</accession>
    <name>A0ABQ8V404_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="24749" checksum="12696078F18B5C6F" modified="2025-10-08" version="1">MAEPDTFVSTYNEKHNPINIPYPLVNSVPMHPSEVIRIQNEGKLFFCCTHGMICEAWYIGLNSANELRRFRLNDIYDPLHQAHQLKASHKMESHPFPPQSWKWPSSLIELPNTPIKCSKKIGKQMAKNTIPASDDGVTTLWDPKELLFIMKPRNSKGPLQRQQLILRFFLTNSTGKSSNLKSVLKSIINTIFSKINKNGMIYSRISKELELDPTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4A1</accession>
    <name>A0ABQ8V4A1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_849064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="594" mass="61525" checksum="58CE5EDE7399F626" modified="2025-10-08" version="1">MSDSATPKPLSAVREWGRNNDESGSAFSGLGRGKRGGGPGRGIPRGGRGGRGGASFRARGRGRGSGNNGTTTTTTTTSAITSTATKPAEVASKPSTATFKAKLSETTATPKNTPLGKTGGRRRSNAKTIPQITVPPPSTSTSTTITDEVNALVEHVRAGALTPNGPITPFTPSHIDWAGDEEEDGSLPDLDDWGVSTSSGGAPSTFEPASTVETTKGSNMKPDAISPILVEGLKSLPEPKVPEHPEPEAEVKAASPVPYPERLISKQTSPSETISTSTSSSLYPSFPHKPSSGSVNRPAKNKLGVTGSSRDGSTPLPPRTSRGSRNNLAAIQPVPESSPDINTKNTGKPVSGGVSLSTPTPLTNHGPISLTPPESPTKGLTDSIHAPKPGLGSAEPVRSKANIPASLNINGGSASKVGSYVPPHTRNSRPAFVPTPAPPPSNNGGLTAEFTFPSLSPSPISGHYPTGPRGPGGGPSESAGSDRPHDRFNGRNGAFNGNGSGFNPRYNNHAPRHYQQDPNHATNHFSRDRPVHQPQTQSHHSDPLHPGLNRSDSPHHTPRHTPHHSREHSASRPVITGDAISKLARTIAGSPAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4M6</accession>
    <name>A0ABQ8V4M6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Xylosidase arabinosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_890017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11576">
        <property type="entry name" value="GH99_GH71_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="587"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="725"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="860"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="926" mass="102063" checksum="D321FC3289E5DC89" modified="2025-10-08" version="1">MDGQDGSRVLKRADPSTIQDKFLVGYQGWFTCAGDGEPIDPGHHGWLHWFNYPIPNGGRPTIDPWPDVSEYSPSELYTVPGVNSPSGEPATLFSSRHPKTVQRHFHWMARHGIDGVFLQRFLGQCDTERGSKGIPRLRDEVHDRVQEAAEKEGRVFAVMYDVTGVEPDDVMRIFTKDWIHLVREKRILESPNYLRERGMPVIGLWGFGFDKRKDTPELVREVTRFVRDVTPGGAYIMAGTATHWRRSTEDADRNPAFLDVWLKEFDAISPWMVGRLTDEEHVDMYAQHYMKADIELLRKSHEEGGRKIDYIPVIYPGFSGLNLSEGKWKFNQIKRNGGKFLWQQIFNAKRLGLRVMYGAMWDEYDEGTALMPVVEKSRLLPRSDKYSFMALDADGYDLPADWYMRICGFAAEGLRSERMIHETFPSKELQDYWSTRPRFEEIKIKSGDFVSGSAGELDGGQSYQGWLAAQKDSKDEAPPPPYSLEAEHSTATSSQAQASGQSQPADAIASSSHHAQNESIVASSLSQPSLANDTTASSVTRPPLHPSHPSRSSSSSSSSNAPISPPTHPSRSRPPEPNRLSRPQSISASRPQTQSQPQPQPQSSDQAAHPAGSPHWPPAEWNADTNRPPTSMSYQPYRPNRTPSHASLIPETSSSRPTSPYDSQSGILHPSCEPSNRPNIPQPPVASVGSTLSFPQAHVSGPTSDHRVTGTVSYTPPSGSPSFPPGAYGPAAVQEGSSHSAHTPHPSSPSFRAEFYGPTSSQPPTVPYTSHPSHPSYSTQSTFGSSYPGLSPPHSPSVGGFPDPYYNGHPPPPSQQYQMPGYPPSQNTFPHSPYNSPGQWSTPPSIPPRPANLASPTSPPNQYQPYPGSYSSYPQHMPSAPSSSSFSSYARNAVDKVAGQDTRQQLENKLGSLAQSGSKLFGKFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Y8</accession>
    <name>A0ABQ8V4Y8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiamine thiazole synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Thiazole biosynthetic enzyme</fullName>
            <ecNumber evidence="6">2.4.2.60</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_925459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:55708"/>
            <dbReference type="Rhea" id="RHEA-COMP:14264"/>
            <dbReference type="Rhea" id="RHEA-COMP:14265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:90873"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">During the catalytic reaction, a sulfide is transferred from Cys-207 to a reaction intermediate, generating a dehydroalanine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the THI4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.60" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03158">
        <property type="entry name" value="THI4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027495">
        <property type="entry name" value="Sti35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002922">
        <property type="entry name" value="Thi4_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00292">
        <property type="entry name" value="sulfide-dependent adenosine diphosphate thiazole synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43422:SF3">
        <property type="entry name" value="THIAMINE THIAZOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01946">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="100"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="286"/>
            <end position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="2,3-didehydroalanine (Cys)" evidence="6">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="34793" checksum="A696F2CB6E52A555" modified="2025-10-08" version="1">MAPVQTLDNNKFVETRFGKQLKPSSKSTTYDDVAENYDGQYRFAPIQEAQVSRAMIKRYFETMYDRAISDVVIVGAGSAGLTCAYHLASTRPDLKITIIEANVAPGGGAWLGGQLMTPMVIRKPADRFLQEICVPYEDEGAYVVVKHAALFTSTLLSRVLAMPNVVMMNATAVEDLIIHEDHAGQQRVAGVVTNWTLVALNHDTQSCMDPNTITCPVVVSATGHDGPMGAFSAKRLVSAGLLKELGNMRGLDMNRSEPAIVNNTREVAPGLIMAGMELSEHDGKNRMGPTFGGMIGSGIKAAHEALRVLDSVNVVEGKVVSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5D2</accession>
    <name>A0ABQ8V5D2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33406" checksum="42FF92749866BA5D" modified="2025-10-08" version="1">MAERMDFDPAKIPAPDYTSEAHAFMRAALIADANTPEITSNELAAQRLKDQWQVYIEGLKAQYQAQLQEAETQREQRSQEAAEAERLAEAERQEKEKELTKEAEKKRLPIYDFQKGLGVDSIPLQLHPYARKMMMARKYVPLWYFLPDAAVEAKERSKESLDTNHLQFAVEDGNSLAGSTVSLVGSHSVRASPNAIPDSQLSWPQVMHAKSAFLNAIRLGTWPDHFIAMFAGFYSNMDMHRELQEQDGDQVMAHYHAEMRLAWYDAMERKAPFDLSIISDRVLGEKTGKESQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5E0</accession>
    <name>A0ABQ8V5E0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_888093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051750">
        <property type="entry name" value="Trans-sulfuration_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699:SF1">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4474167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="637" mass="69347" checksum="852BC48FBEBF54CE" modified="2025-10-08" version="1">MTATVVETIGVAPVALGLPVPPFTPHAISVSLPTWRDNVAYEAGDKRVMDAMVCGYPRFFIGLGIRKLAEICAHKFGVDGESAMLFPTQKTADACRTFILSRSALEGVLAQARLIQLLICPEDKANRTILVNSEDCDCNGSASLLDLHIVLFSSEASQVAMQFWQHSGAGISSRLAEQCLSLLPEGSPTFSPASPPARGISFKSSNKHYGVKGTRRSSPPTIAEDLNADHSVYLEERYGRNLPIAAAAAAKRALHRRIAGVLLRDDPTGAQSPLFGHSTRGVSDVSEGDVFLYPGGMNAIWNAHQLALATRPVGKSVCFGFPYTDTLKILQKWGPGCHFLGHGLDSDIDQLEKILEEESKLDPLKPPILALFTEFPSNPLLRSADLPRLRTLADQYDFLIVIDETIGNFINVEVLPFADIVVSSLTKVFSGSSNVMGGSLVLNPKGRHYTILRSHLDSNYEDTYFDQDAIFMERNSRDFQRRIRVIDINTEAICDFLYSRSQAAGAPNAVIKDVAYPKYTTPEHYAARRIKANAQTDVEQGGYGGLFSVTFTSPSASHAFFDALPCYKGPSLGTNFTLACPFTILAHYNELDWAAQYGVDADLIRVSVGLEDTSELLAGFNLAMKAAEAAVTQNETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V653</accession>
    <name>A0ABQ8V653_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongin-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_611496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4470719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="117" mass="13294" checksum="9E8D1D05A07DC0ED" modified="2025-10-08" version="1">MNEDHPMDGSVEGDPEDWVRIISNDGYTFLLKRKVANMSGTIKNSLDETGGFAEAGTRTYRSQERGIIVQKMIEYMSFKAYYSNVGPKEEIPVNELTERLPPEIVLELLLAADYQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V699</accession>
    <name>A0ABQ8V699_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_897202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="663" mass="75736" checksum="C27F3F8959BC22A7" modified="2025-10-08" version="1">MYNLIDSIVDGGVPWNCFQTVPDEGLSAEAPEWQQTSYQIWYRNPDTVIANILANPEFANDFDPAPYVHINSDENWAWRHATQIYEDDKDDCVDGAMIVPIILGADKTTVSVATGHVKYHPLYLSIGNVTNSARQAHRNAVIPIGFPAIPKSDRKYDNDSDFCIFKKRLYHTSISAILQSLKPGMTNPVIRKCPDGHFCCIIYDLAAFIADYPEQVYVSGIVSGWCGRCQGIFSNLDGLSASDWHSQHIDQLLRNEYGGEGHTLWDNFGIDEHVKPFTESCFKDSLVEWCIEYLTIEHGEARANEILDDIDRRLAVVPAFPGLRRFPHGRRFKQWTGDDSKALMKVFLPAVADYLPEDMMKCLTSFLDSLTLMKHVSKQSSHPWKPSTITAKFLKHRIQILLTNQQLDKLMSQHQHTTPFDAENEDVGPTDSGCSLADVKLAKTRERGYPWYLEELGPHINQPNLEYLMRRFLQEQLDQSDNSSTSSMYDIDINSLPEIPLTINVFHSAVAVYFAPSDPCGIRGMRCERICSTPSWYGQEHRDCVLVSLNEDTPGFLGMSIARYEWRIYPCALVHWYNNHRERPDARTGLWMVKPADWDPEHQQRDPSLAVIHLDALVRGVHLIPVYGSEPVPIRLEFHQSLEVYKLFYVNKYADHHANEILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6G3</accession>
    <name>A0ABQ8V6G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="39490" checksum="F24DF1B871A54360" modified="2025-10-08" version="1">MTIRPNLTCCHTRFRLYETSRDHEANRLSSSRTSNRIFPTGSSLQSLVPKIPASTPTTGPMSPHYNYENRSPVSKRHRQTEPDDIMINSKGSVDYLGLPAGSLISENPIQSKMSLHCINLRSMSPRGLPSSLSSERESALVVEDSTLDVGQGIVPTALLDGLNPRSSSSCIFVLLPSASTPKSVPSPVQSKPSPLVVNGDGMPPNLKAIVFYKKRAYKWNGIIPNLIHNMIESGIKANAAVQAYHVEVFFAHFDQPPKFKDHNFGISVRYYVDTARQKDFPGHKYGTFTFIPKWEDNQPTLENQSLDSTWQYIEHLYTATKPSNSTKKSFNPAAQSFDPSKQPVAPYDLKLEWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6N8</accession>
    <name>A0ABQ8V6N8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_845715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27438" checksum="B01942972FF5D34E" modified="2025-10-08" version="1">MTDPGPLSTKIKNTNTNAALPPTRSSAFYLDFAIFEVENVLYKIPRARLAEESSLFETMFTLPPGAGNTSEGEDDDHPIHLPQTERKDWECLLKLLFRNPISGPPEFTLDEWVSILKLATKWDMSTARTCAIEKIAEHDGIPAKKIRLARDYRVPRYFIPSLVQLIGRSNPLTADDYKDIGVECALKVVSLRERYYDPNHNAGMFRQQRVASDISSPTNNSWNGIVSEIHKTFTDQDEFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6T7</accession>
    <name>A0ABQ8V6T7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C8R41DRAFT_523676</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08689">
        <property type="entry name" value="C2_fungal_Pkc1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11620">
        <property type="entry name" value="HR1_PKC-like_2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037778">
        <property type="entry name" value="C2_fungal_PKC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037312">
        <property type="entry name" value="PKC-like_HR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="22">
        <location>
            <begin position="119"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="18">
        <location>
            <begin position="212"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="442"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="508"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="764"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="21">
        <location>
            <begin position="1024"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="66"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="576"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="582"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="633"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="710"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="735"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="793"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAJ4477124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1091" mass="122692" checksum="AC6247D2051965B7" modified="2025-10-08" version="1">MASELDQKIQDVFKHIQTERKILEASQLLRQATTNQDVLRRNDAKIRETERSLSYFEETLRELQARKMQQNEPGRSSGPQVPPKEDRYGRDNPADTSMKRSSASGSPQTKAYSNLDLIKAETPLTSAKISKMLHQLEFKLQVEMQYKRGIDKMAKLYQADGDKKSRQDAESKKVESEKKIQLLQLARKRYKNLHVLDDALAEEEEEPNGTGIEGERKENLRAKPLSGILSVTVRGARELDHAPIVTRFRSSKNQVVETSVSLKVEGTQLARSHPSRTDRWNEDFEITVDKANEVEIAVYDKQVGETHAVPIGLLWIRISDLVEALRRQKVFMESGQGGWVTAGAMHGDAGHPNSADLNAPLSFGAAPPGGFGPQGGMGDGIPQQPSEGIEAWFAVEPAGAILLHLNFVKENVRKRQIDAPLGGLGRQGAVRKRKGEVHEMNGHKFVQKQFYQLMLCAFCSDFLLNATGYQCEDCRYTCHKKCHEKVVTKCISKSNTGDDEEKINHRIPHRFEPLTNIGANWCCHCGYMLPLGRKNARKCSECDLTCHANCAHLVPDFCGMSMETANTLLSDMRDIKKHRAQRPSQPSAPQQPSRHSPPADTMGRLKLSGAPEPEPDPFGRQQPSLPATPPSGYPQAPYYPQQQQQQQPPLSGPPPGARPPSASVKAPPAYAQEPSRPQTSPYELQPGAYPGSRPPGPPSPVQTKIGLPSSPMQQQRPPDRSSTVLPTAQTPPQQPQIQIQQQQQQQRQPVRQQTQRRKVGLDDFNFLAVLGKGNFGKVMLAEEKKTNGLYAIKVLKKEFIIDNDEVESTRSEKRVFLAAAKERHPFLLGLHSCFQTETRVYFVMEYVSGGDLMLHIQRKQFSLRQAKFYASEVLLALEYFHSQGIIYRDLKLDNILLTLDGHVKVADYGLCKEEMWFGQTTSTFCGTPEFMAPEILLEQRYGRAVDWWAFGVLTYEMLLGQSPFRGDDEDEIFDAILEDEPLYPITMPRDAVSILQKLLTRDPNRRLGSTKEDAEEIKRQPFFKDVSWDDVVNKRIPPPYFPTINGSADTSNFDEEFTREQPTLTPVHGQLSSRDQAEFNGFSYVASWADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V741</accession>
    <name>A0ABQ8V741_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pkinase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_553992</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09534">
        <property type="entry name" value="SAM_Ste11_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029458">
        <property type="entry name" value="Ras-bd_By2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14847">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01304">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="9">
        <location>
            <begin position="75"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="917"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="148"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="536"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="628"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="831"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="323"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="628"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="668"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="734"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="843"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="868"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="946"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4474524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1185" mass="128662" checksum="B4D3B17F2BD79C1E" modified="2025-10-08" version="1">MAAVAVNGLLLNNAADNESPPASPSFPVQVGVARSFVPNIRGQISPFPTTPTTGQMPNPLDPPPGVSYADFIRTWTDGHVVRWLTDIKCGHHADTFSANDIRGDILLELDHTTLQEMDITSIGDRLRILAAVKALRLRTAKSSLPSRLDIFTDSTNGELPETSPTTRKRNVRPAPLHLNPTIQNDLPRIIREQQPDSARSVNAPGFVNHPVRPLPQPTSHATSNGTPLSTTSTGSSSGPTPLSNHSTRTNLPPLPPPPRGQPPPPPTNRTPARNNINGVNGRHTPTPGENAPSRDLLSPSPNNWAGYHLPADPRPGNPGGGKTPQSSRSTSPLPARPNSRNGSPSVSVTTSPNNKRASPSVTNHPYSSGLQAPNSQGVINLSPIQEQFTNPSGVSPPNQNFVGNRPFNPSTPSHSNAPSLEDLRRKLVKFYLPDEGLTYTIDVDTCVGGVEILEKVLKKFGKGGGRGLGADADAEGTLDHVTTEDGGLSVDGWGVYLENGSGDLLSEGELLSVCHAPLDHPTRENPLVLRRIARARRDGNVSPSQSKFTQSTSKATKRASSYSILNDLGVQDPERALVPPSPTISLSPGRLSPGSASTSRPSKLRNFFGQRPPSELITNHLTEFFPNTEKKVLERTKRQSMMTRSNTASSRMSRISRVSTASKRDSVASWNPSLPSRFSSSTQGSAHTRRASSHYSPRASLSSLPPPLPDKTLRDDASIITSSEELPRMSLSTEDGKSIDLDREVEDTSGRSIDKPQLLPPIPFPSESLSESLENLTRARPGARMSRTSSNASHRLSFMTELRSKRDRSDTASLMTVDEITKEMENRRISKRESIAIRPPESSDTDEWTEVENEEGRSSTMGLNEDDKAGDEEYDDDDDDEDTSLDDEDSASEEADDEDEDGAAGDAAKLKKINNKWIKGALIGAGSFGKVYLGMDASTGRLMAVKQVELPNGSAPNLERKQSMLTALEHEIELLQDLQHDNIVQYLYSTLEDDCLNIFLEYVPGGSVTALLRNYGAFEETLVSNFTRQISLGLSYLHERGIIHRDIKGANILVDNKGGVKISDFGISKKVDVQALTGARVHRPSLQGSVFWMAPEVVKQSAHTQKADIWSVGCLVVEMLTGEHPWAQLTQMQAIFKIGSSAKPTIPSDISSEAHDFLTRTFDVDYEARPSASELSQHPFITRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7M7</accession>
    <name>A0ABQ8V7M7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aryl-alcohol oxidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_527113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047166874" evidence="5">
        <location>
            <begin position="28"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="41"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="461"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4476825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="611" mass="66127" checksum="E2ADA07B2B2C81DA" modified="2025-10-08" version="1">MLFRLVTPSIWVLLIWLFSNFDAFCSAVLYNSFSDLPSKTYDFVVIGGGTAGNVLANRLTENEDWSVLVLEAGGTNIDAFEIDVPFFSLNIKPQYDWNYTSTVQSGLNNRTIPILRGFILGGCSSVNGMFYTRGSADDYNRFAAVTGDEGWSWDNIQPFLALNERFEPPADRHNTSGQFNPLVHSFSGVNAVSLPGFPTNIDSMVFDAVDELGGIFHYNEDVNSGTPLGFGWLQKTVTSQGRRSSSATSYLAPEFISRPNLDVLLNARVARVLPNVSLTEHSTSGLAFRTVEFAHDLDAHVHTGPRQRVSAAKEVILSAGVIGSPQILLNSGIGNSTTLFDLGITPLVNLPSVGQNLTDQPSISNEFLVNTTQTFDDLKRNATLLNEVYTEFNKSGMGPLVDTGGNQISFFRVNESLTDIYGDPSSGKNSPHLEMVPGNGFFLTPPATGHYLSMSIVVVSPASRGSVTINSNNPFAPPLIDPGYLTSPFDLAAMRQALEIMFQYLSAPIWDGYILSAFGTLANITSLSDDNILNTYIRESSSSTAHPVGTAAMSAKGADYGVVDPDLRVKGVVGLRIVDASVFPFITSAHTQVPTYVIAERAAAMVKSVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7U4</accession>
    <name>A0ABQ8V7U4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_624221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="414" mass="45921" checksum="0CAF20A7830207E8" modified="2025-10-08" version="1">MKLKALGIECWLSSSHTDEHPIGNTETSFSETTGTTTVRTSVFPHEEPDSESESESESEVDYYLSWRTSPNEPMSLWCIVFSRKPTGHLETVESKVWMCSSKQNTQQRSSEHFHEDPARRFRPHSIKSSDNMGTLRLEIKRLNGTVNAVCLLGVDDLDIDILDEKYPWIVFEFNFKRKNNDEVSAFSNPTTTRIYSQKRKRKASASSSASTSSSPSRKHSFTGITPCENTLSSSRITPRAGAGLRRKSASSNPHSSHSVPALIAARSPRHSLHTNTIVDLPAPGESNVKASSSGKAKEPNSNFSPPASSEPDQVKATDNYVSGAQADSDILNHSGKMKASEFSQDVSSSLASPIEVIEREAEELEKKSRELAEKIVAKKQKSCLACRNLLRSTARVPRPKLPNLRLKFKNRKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V806</accession>
    <name>A0ABQ8V806_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="157" mass="18144" checksum="4CF50F210BC7AA4F" modified="2025-10-08" version="1">MNIEFRMDVFISRSYLMKNQGKIDDFERRKWAALCLSPCVGVQPVGVTLSGALYSIHFLDLEPLSVKHSLWNSFSSSITKHSRECPTQPCFLNEMWDLRIWLFFGITGYESRPFPVNLTIYPDKVTTLSGLTKYFIQAEIGQRITVPIEKSKSFEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8A5</accession>
    <name>A0ABQ8V8A5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_922549</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1125"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1132"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1200"/>
            <end position="1216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4479852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1225" mass="136718" checksum="DD89E250EDFA5DED" modified="2025-10-08" version="1">MVAQTRHTGQPSPKKLAFREKLITKGQSNDTLLKKLKTLHSELAEMDQELVDVNSMSSVRKELVSSSIMLHKDRGVKAYAACCMADILRLYAPDAPYTQAELRDIFQFFFKQLSNNLKGPDVTYYTQYFHLLESLSTVKSVVLVCDLPNADELVLGIFRDLFTMIRRDLPKQIETFMAEILVAIVDESSSLSGDVLEIIMAQFMDKSARVEQPAYRLAVSVCNQTADKLQRNVALYFTDIIVSNSEEEDFEQIRIAHDLIKRLHASCPNLLPSVIPQLEEELHADASTLRAIATQVLGEMFCDKSGGDLARNHPSTWNAWLGRKVDKSPTVRLRFVESSHGLYSAPPEMAEAIESALNGKLLDPDEKIRAAVCKIYSQLDYETAVHHVSELQLKAIAGRVADKKLTVRFEAANSLAKLHGLAYPEIENNNVTAISKFSWIPNELLHMTTIVVDCRTVVEQVLSDYILPLPSFTPSSLNSKTAEVDETAWTDHLLNVMRYLTDQSITALVLLSNLKPNRPSAIDIFVDACVQYNGGVIDENEERVTQKLGRIIEVISVYFPDPAKMREDLKAFAKLNEPRLYKFMKTCLDVETDLKGLVKAQHDFIRRLEQSSSTLTPSLTALLRRGSLHIANTSSIPTLLLRLQRSQGTTITKTNVAANHAQILFTNIAKFCPALFKPHVDELITAIEDGKNDKTVAVGLQALASLVKLDSLLMPLESSIVEVIKSHVLSSNHRHAKFAARIFAFCEEKNTLCDGVVESIADSLSKAPADQLIAHLVSLAQFARFIPDAFEQKSDVITAFLLKKLLMVPSLPPDDLEDDGEEWVEDDEVSNNLKAKIAALKILRYRTMSHANSKNAVDISTPVLKLLATILDRGGSLAGNDAVEEDRKALSRIRLQAAISLLYLSTVPAYADALTPKFDTCFNVRMSFLQKLVPLLWHRKLPAKYHLILFLTAHDPEEDIKQKAAAAASGLFKKLPSDLRTENLEFVFIRLLHLLAHHPDFATSQSELRDIAKYVQFYLELIGSEETIPLLYHLASKGKTVRDPESQAYSENLYAMCEIAQELIKFRAQHNNWTIPTFPGKIKLPHDILRPQPNAEIANKIAKQTFLPPDASSWLAEIVVAAPREKKERKIPAKRKAATTNGHSKRSRKKRKQTDSSDEEPFDVHTDGTDIEMSDGPPVHPPDVDEAEESSGEEQLGRGARSKAKAKAKRKSRTLKKAGTPSSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8G6</accession>
    <name>A0ABQ8V8G6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_771513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF9">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="31640" checksum="B76C0B6B61A26A73" modified="2025-10-08" version="1">MSNISAPPVNWQPDPDFRGTFNIVSTCLTTLLLCLWSAVHVDVPSHSGRCRELWVRVGWISVGLVTPETLLFIAYRQWTIAGEIFTVANPCEASNKPWHRLFLQLKEYLKWGGRKHRWTMMHSYYAAMGGFVFDTQTEDFLPASYRNGRAVITPEGIQFLLRNQPDLFPDLSIEEISDRSKANGLLKSVVVVQVTFFLVNCIARKIQRLPVTLLEVTTVAHTLCSLLAYAFWWNKLLSVAHPTFIRGEVAMRTCALMCMASTCRVSYGLASCGTRQCVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8P9</accession>
    <name>A0ABQ8V8P9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_488521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="172"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="788" mass="90268" checksum="BD480714624E794E" modified="2025-10-08" version="1">MTANPAPVSTALVLPALPPAKETRYKSRTTNLLIFREGQLGDKRDAVIEDLGNMVPEVDLDWFFENLLPPMPKGIDTATVVEQLRKSGVVTENGWAGFSLNPQDERRHEDVVFAQLQPIFKAISDTVQELDPSLQQTFTLLLQPTKYPTSERACTSKPDNCWVAIEDVERIKNDPGRFYTWYNIAGPAEDKKLPESSREQRNKNVAQIVFNMQQIMSLDPCRRFTFGTTMQDRELRVWYACRGFVLTTKACDFLKDYHRLVHLYIAFAFSSRVDFGWDPTISCISPEFIWQDERKRRVYKIQVRDDEGQVKSFKTIRILADYAADSTISRATCVWLVEDEQGIQYVLKDVWLDMDRLPEHIIRAQMLADVLEKCGADDNVTLQNHLLTPYICGKVFVNGVVDTTDDMMHNQPPCLASNSVFSLKLEQTKNPLRQSCDPASSSATLSTTTKGYSHNRNSQAKPIATWQAPQPPVLRRKYHYRIAFFEYGHTLFAEKSLLNIYTTLADLLTALHIIHRSGWVHRDISCGNVYYYTGPTEAEPRGLLGDLEYARKCDSREEHQMRTGALDFMASEVVSQVWNYMVPPPRPPPRKGVVYNPPERAPFTYTPLHDLESCLWLLVYILFFNDDALNPLLDPQSLILRNKKTNQLFSRKAETFWRFYFIRDWDTINIHTTGLSPTLESAVRTVSYFASYLHAAFQEIQKSYTSVTVEESFLQTLYDNILPLVNEDSPLREEIRGIQLKSIPKPVMSAGEKRKAEEEADEDNVSNLPKSKKSRTNTSLHGRCGTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Z6</accession>
    <name>A0ABQ8V8Z6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_886077</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4480724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="32792" checksum="ABA307FF5C7D86DD" modified="2025-10-08" version="1">MRHCNRCRRKFYSEQSFHTHCCNRNDHPYCVSCRLPFRNIDDLHCHLYQYHDEDTSFSDSDCDSNEENSSNPCCHTCNRQFRSSASLYQHLAGSSRHNWCFVCSKDFSSPNALNQHSSSQVHRSRDIKCPLCSEQFKMASAIAQHIESGACHHAINRHTVTQAIHNLNLIPTISINRRITGNSESIPTSRAITTYSASECAYNGTAYECYLCDRTYNTLNALNAHLGSPAHDSKEFRCPKCQKQYSLISGLVQHIESEVCGVARFEGVREQMLELTSGHHFQRMLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9A7</accession>
    <name>A0ABQ8V9A7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GPCR fungal pheromone mating factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_896762</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001499">
        <property type="entry name" value="GPCR_STE3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097:SF1">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02076">
        <property type="entry name" value="STE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00899">
        <property type="entry name" value="GPCRSTE3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4481808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="30098" checksum="E9FB62D5738C80A8" modified="2025-10-08" version="1">MIWASLIGLIDFINSILWAATHVILAGTFAIPLSSLCIVRRLYLIASAKSALTRIEKRRAVIFDTTLCLIVPLVLTALQYIVQGHRYCIFEEIGCMPYVYRTLATQFLVTFPPILTGLVSAYYDKCPSSLNLLELKNLQTPACENSFTMNRFIPVVIFAMLETCTTPIAVFALVMNVSAGLLPWISWDYVHADFSYIPATPSVIWRSNGIDEASLELQRWINSSCGILIFLFFGTTKEARQHYSKAFYNLKSQFRPKNSLGKASNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9P6</accession>
    <name>A0ABQ8V9P6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_467321</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF1">
        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4482688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="525" mass="58716" checksum="C92E894BB161C8CB" modified="2025-10-08" version="1">MATHEPDQKNLEEIHVNEKAFPVSPVFEHLRSDSIEESDTSVDEALQLVGKERTSEFSDEFNRRVRRKLDLLIPPLCAAVYFTQFLDKTSLNYASIMGLPITGQNYNLVSMAFYLGFLLFEFPTVYISQKTRAAKYLGVNIVLWGVILMLHAVGTSFGAFFALRFLLGMCESCVAPTLILIISMFYKKDEQASRISWFYVMNGLTQVFGGFIAYGVSFSNDSHIAPYKIIYVLLGGLAIIVGFSVLIWLPDSPVHAHFLDQEERIAALERVRNDQGGVANKKIKRKQILEAFTDIRTWLIVLTTMMTSIPNGALSNFSNIIIRNFGYTSRQTLILSTPAGAVASLMTLFCGWYSDRKNERMIPIIIALVPTIVGAAMLIGLNDSGKKGALLFATYLIGTFGSSLSTVYAYNASNTSGHTKKSTVNAMTLLTFSIGNIVGTEIFLPKDAPAYIPGKIAIMVLLTVQLGISLLLRYINLRLNRRKIAQIEELKRSRGWTEADVQKEREKHAFMDLTDQENIYFVYTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Q1</accession>
    <name>A0ABQ8V9Q1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">4'-phosphopantetheinyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_922083</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="8">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4482702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="128" mass="14588" checksum="2A54E3B5187768D7" modified="2025-10-08" version="1">MAILGIGADIVRIPRVFAFLQRRGPEKLAHRILSDVEVVHWDASRSGSEIKLEDAQFLAVRWALKEAAYKALYPNYRPTWKDLTYYPLGAMKLGSKPVLSFKYQQDLSFHCSVTHDGDYVFATVVVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9W6</accession>
    <name>A0ABQ8V9W6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">A to I editase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_840543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910:SF62">
        <property type="entry name" value="AT07585P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910">
        <property type="entry name" value="EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A to I editase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4483115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="453" mass="50383" checksum="3065AB8B2AE1E938" modified="2025-10-08" version="1">MNQSSPSDDDHISLIHTLYSQLKVYPQPSQYTVLTAFYLTSSASSECKIISLGTGTKCLPKCRLPVRGEAVHDSHAEVVAHRGAIRWILEEIIRERVQGSGWIERHADTYRFRERIQIHMYVSTVPCGDASTRFLAASQDPKMAFLKDSAVMAHIEGIPARGRDNYHLFNILRTKPGRADSPPTLSLSCSDKIASWSWLGIQGAFGAKLFEGGTYIQKIIIGEVLPSRDVDLIKIVKEDCERALGGRLEGLLPTDQGPYSLHKPVIAFTPVPFIHSRLVVGLTSTSSNESLCWHADSIPPHTPPPPPQTLLSSSSFFPDSDHFRNSPSNGTVQVLINGYKRGISPKHRQKMQNSKFIPQVSKLSILRLYARVCKDVYGVEIPSTQSYHETKTDFHDFSDHQSANANVLSTQPVSAYHEAKILLKGPSAPFSAWWDESARSLVLDTRDLTTKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAD7</accession>
    <name>A0ABQ8VAD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">3-ketoacyl-CoA thiolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_896616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="7">
        <location>
            <begin position="20"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="8">
        <location>
            <begin position="264"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4484082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="41287" checksum="108D11E461601DEC" modified="2025-10-08" version="1">MSTQVPRGLAAVLEKKPDDVVITFAKRTATGRAKKGQLKDVPVDEMLYHLFKATISGAKIDPAKVDDICVGTCHPPSPLYLSRAAALAAGFPHTVPISTVNRLCSSGLMSVRNIAQSIKSGEITLGIAAGSDSMSLNARPTPEISAVVDEHPEAHDCVQVAEVYKVPREKQDYYALISHTRANEASTKGIFAEEIVPITVRGTTISVDDTIRPGVTAEGLAALKPAFPQWSPSTTTAGNASGVGDGAAVCVLTTRANAEKEGMEILGKYVTSAVVSVEPKVMGISPVVAVPKVLEMAGLTKEDIDVYEINEAFASQFAYCVEELGIPIEKINPNGGAIAISHPLGMTGTRQVVTGLAELKRKNKKLLVTSMCVGSGMGAAGLFVNEARHGANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAH5</accession>
    <name>A0ABQ8VAH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_769646</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046379752" evidence="5">
        <location>
            <begin position="23"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 TIM-barrel" evidence="6">
        <location>
            <begin position="76"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4484443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="505" mass="55377" checksum="0146C06355AFED5D" modified="2025-10-08" version="1">MSPTHRLYFLILCAFIPRRVQTQQIYDVWQTTWDRSSLFTSFPRTTSTAINFNPSTNSVPTSVNIVVDDTVEYQDIVGFGGSLTDSAALILKNLKTANSGNYWNLLNYMFNPADGANAAGLSYVRVPIGASDFSASVYSLDDSNGDTSFHSFNINRAPAYLFEVLRDIQTINDLLKVVHVLPWSPPAWMKDSGTMNGGSIKPDMVSFYPTYLLKAVEGFQAMGFPIYANEPQNSNPTYPTCTIAPDVEAQIGSALRSLLNDNGLSNVKIIGYEHNWDDAGAYPVTLIHDAPDAFAGVAFHCYAGNVDNQDVFHNAEPSKDVYLTECTGTLGSDWWGDIKWDMDNLWIGALEHNAKSGLMWNIALDGNGNPMLPGAVSCNKGGCRGLVTVNNDGSYSFNQDFYSMAQASKAIIPKDSGGPFGNRIHVSVTGSLGWTLRAGAYITRRKNPSDWSRYSIVVLNWYDTSPAGSWSPTPVTASISFRGMQATYTFPVGVTTLWWYAPPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAJ0</accession>
    <name>A0ABQ8VAJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="29173" checksum="7F72E94DA5E68BC9" modified="2025-10-08" version="1">MLWNEQKREQNGTMEDARVLIKELTAYVYGESLFDIPVTDARERLSWWKDRSKDSGARQILKLAIKLFSVSPSEMCDERSASKLSGLDTAKRNGLSGQNLIQMTQLQQYWRYGFLGPRYTHTAQLELDNSLAHNLTQIQLPAPTPNDLLNPAQPNTTDKNLSFDISDPYGAKALDEEEDSEDESGTDDMDGPPIIVRAQMNRLKIESIVNLFNSKLLEHYNPSPATKDIQKEKPSTSGSHSQKTSTAKNVDWSPKDLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAM3</accession>
    <name>A0ABQ8VAM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_769846</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="234"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="44"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="568" mass="62284" checksum="3849AEF20CFE9AB4" modified="2025-10-08" version="1">MLSTPQLDLAFDNDDWTPQIAPRLFRSTSSASSVSSWGVTSIGRGFEWDQNDDENSIKNAQPQKPEKDDYRLAFDLNNDEEEKPRKLSPNSAGSSSNIMRPVTNVTPITTTSALLSEPFCMSPSQSRSTSPVIYSPTPSSAPSSSSPRPGYPSRTPSTPRPRRRSSQQRVSLVAGRVMIAPRDSPTQPSLEPQSLNGLQRANSNSSFLSVASSTRAPSPTSHESFLGNRKISEFEIEGEIGRGAYGLVKRGREKLENGLLGPPLVIKQIIKSRILADCWKKHPKYGTIPIEIYVMSAISNTSYVLPARRPWDPLRFASADSVENDWIEAKVVRGHPNICPLLDFFEDNHYYYLVLPSTTPEPKSGEESVSSDLFDLVESFPQGLPPNSIRTYLGQIADALCFLHSHGIVHRDIKDENVVLGPHGRCILIDFGSSGLMKKNGWDSFSGTLDYAGPEILRGERYYGKEQDVWAFGVVAYVLLVGECPFMTAEEAQDGLESPFANASIALDERCAEGKELDGEEPDGGSALGDAAALVRACLRVEVAARPTFEKILQSRFLSGNGGWTKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAZ6</accession>
    <name>A0ABQ8VAZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_709754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="1">
        <location>
            <begin position="31"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="124" mass="13565" checksum="0FFF7E934493BD1F" modified="2025-10-08" version="1" fragment="single">LLDPAGIEISESNNELSIRLCSDCMSSLKHHKIPPLLLANNMYLGEVPPELMNLSIVEEVMIACCRTKSYIIHLKEEGMASGPTLQHALRGNVIIYPQRPSAISKILPPDLDDIASAICVIFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB26</accession>
    <name>A0ABQ8VB26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="9">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="9">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="9">HAD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Biosynthesis of nicotinic acid protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA1</name>
        <name evidence="10" type="ORF">C8R41DRAFT_772333</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 3-HAO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497:SF3">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4478880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="20162" checksum="4590247E20BFA6CF" modified="2025-10-08" version="1">MPLSSPINFTKWMSENSHLLKPPVNNFCLYRGGDFVVMVVGGPNERNDYHVNETEEWFYQYKGGMLLRTVDDGTFRDIRIEEGEMFLLPANTPHNPVRFADTIGLVMERERPGNSIDRLRWYCPSSTHEKPTIIYEESFHVVDLGTQLKPVIERWQQTPDLRKCKQCGSVADPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB29</accession>
    <name>A0ABQ8VB29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_721412</name>
        <name evidence="3" type="ORF">C8R41DRAFT_738750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000143">
        <property type="protein sequence ID" value="KAJ4464276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="189" mass="21874" checksum="031FCA3F95D3E7BD" modified="2025-10-08" version="1" fragment="single">QNRNAELLARKPMTEYEAQLQAALLRSNNQLNLQNEWMMSMQAQNVLQDWYAREVRGQLEYKEEKASTKKSARLHVDGRAKLLTSNEFTSLVEQANTKKAEETAELARKRDARVTANQRLATAMIRYDAEVKGIEEKNEQTLKEWEASVQEWEKERDIARTERRKPAWTKPSKPTYTSGALVKPPAKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBC2</accession>
    <name>A0ABQ8VBC2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Actin depolymerizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_771975</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Interacts with G-actin; ADP-actin form.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11284">
        <property type="entry name" value="ADF_Twf-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11285">
        <property type="entry name" value="ADF_Twf-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028458">
        <property type="entry name" value="Twinfilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759:SF1">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ADF-H" evidence="9">
        <location>
            <begin position="6"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="ADF-H" evidence="9">
        <location>
            <begin position="178"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4479424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="355" mass="38422" checksum="5BCA071776F8963B" modified="2025-10-08" version="1">MSATSGIGVSQELSSRFSSAIDSKSVRFLKISILNESLVLDQSISIEGTFAEDLAKLQDLLLENAPAYVLAKLDDPSTEWLAIYYVPDSAKVRDKMLYASTRASLLKHLGSTVFTDSLFATSKSDLTPEAYLAHLKHIAAPKPLSTREQEMEDIRLAERSNAPSYEGSRARTSIVGTGVGLNWTADVESAVKEMGNGDESGLVVITIDTASETLVLSSVAPMKIDTLKSSLPSSEPCYAFFAWPHNYTDPPRREVVFIYSCPSSSPVKHRMLYSSGSTSVFQAAKTFLSSSNSHLNTRKVETSDPTELDEAFLKSELGFDNVTIGGGDSATIKTPLGGDTSKSFAKPRGPARKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC25</accession>
    <name>A0ABQ8VC25_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_488407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127864" evidence="2">
        <location>
            <begin position="23"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="18902" checksum="CD5657D40887F5D8" modified="2025-10-08" version="1">MRFNATVYISFVVFLASASVSASPISSENTQEVDATITHNARVPGEEHIWTLMRQVFEEKHGWTRAQANHLNLHMVHDDGISIRQDGKTFFAEGIPGVTRKCKGVVNAEGGQLAYTDTREVYYSYPGNTLQAFPSKRSARKKKINPNPGPVEQYPLPGAFPEEPSMLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC72</accession>
    <name>A0ABQ8VC72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mug135-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_415022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0612 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013902">
        <property type="entry name" value="Mug135-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08593">
        <property type="entry name" value="Mug135_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58100">
        <property type="entry name" value="Bacterial hemolysins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mug135-like C-terminal" evidence="4">
        <location>
            <begin position="206"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="86"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4486955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="28436" checksum="DFB162708AB13291" modified="2025-10-08" version="1">MAVPAPPNASGIFVPPPTQNPPTLAEVGDAQHYLDNLLRVQAASSNMQPPTNVEVGAATLYVHEVAIKCAPQIAAPPWLAPIAAQLIHLTTNVDNLNNTVNNLSDNYNKLNNTVNNNYNNLNNAVDNLNNTVNNLSDNYNNLNNTVNNNYNNLNNAVNNLSNTVTNLEATVDARFTGLERSMAILQNSTKAYGLVTPYNNILNDAGAPLPLSPITCAGDLANLSDADIRTWFIYYFPNRTLSGTSHTEKKVEIGRYIGCSVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCK7</accession>
    <name>A0ABQ8VCK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GRF-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_921174</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4487006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="6">
        <location>
            <begin position="361"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="163"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4487006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="433" mass="47154" checksum="7DF4A05C14ED75F0" modified="2025-10-08" version="1">MIFLRSLLTEVGWNTKLSTRASNYGTRIDYILVTPGLLPWIKAADIEPSIKGSDHCPVWIDLQDEISLSGGGNSTLKLQDVMSCPTPDKPDREPPRLATRFWDEYSGKQRLLASFFNTGSARDKIKPEVVAAKATPTTNSDNSNVKMLMTSCESTLHNMTIPQPVSMSSSLPSITSVSPFPTSSGTSTPTSTYSPLNSMKKKKTPPPSTSSSTAGTETSSSAIQTKPKKPKGDVQNVKDLKKPGQSKLSSFFVAPPTTRNTSNSKAKNSITLKIKPRRSESTANLADTGTQVIVDLTASDDKDGKYPVAQTLQEVDEDLQQAIQLSLSQISSSSMPSQSSPISSSHEAWKSLLKPREPPKCLVHNEVAQEFRVNKPGVNKGGLFWVCSRPAGPGYDKGHSERPREEVDSKWKCNYFVWSSDIGVNRTTKQSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCX0</accession>
    <name>A0ABQ8VCX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance-associated ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_767664</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="472"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="556"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="993"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1037"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1122"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1175"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1227"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1252"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="321"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="671"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="997"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1317"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="931"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="934"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4488652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1578" mass="176290" checksum="2424ED24F6AA9B1F" modified="2025-10-08" version="1">MARFQLEIALALAVLIAASLFHLVINRQKDGKIQLPVNATESEQSPPDAFDVTTTEDFLEGYPIDEEIFWKKLRIRKGLLCFLLVVILVLQSVQLSVSGEHGELAERLINICFAAYLTILSARSVRQDTVELNSQSIVHLTVLLTVASVTLGVSAILPNTPPLTAFEYSEETISESTKIWYASVSLYVMACFIAFTTPRGPSLHFPYDSIYSEKTVSARTNTEKENVTGVYGASCWGYLYFTYSTKVVMLGNTSESLEIADLPIVPANMRATVNYFEMKKAMKRFKLKIGSWRPRIGSGWNIGYTLFRYNLGIIAIQFWIAVASAILFYAPAMFSRMLIAYLEMDPERKDRGWGWVYVVGMFLSNIIGFFTSAQLWSISTTTLQTRFRIQLSTILFAKTLIRKDSVSSTPPKKDKDQDHKSSENSSDEDEDFTSKAQIMTLMTTDTDRLSEFAWHFFALVDSPIELVVGTIFLYRLLGVSCFFGLAVTCLFLPLNHFAGKVVVGAQDNLMKARDERIALMNEILGGIRMLKFMAWERSFEARVMKIRDRELRYQRLNYIIETCFNAIWNATPILVTLVSFWHFTVVRGEDLTPSIAFTSIMVFSELKFALNALPETFINMLQGLVSMRRIEKYLNTAEIAPVPPLSEQPRHIAFQSCTVTWPQDRSGGDSSIPPSVASTPRQKFVLIDLNLRFPTGELSLVCGKLGSGKTLLLLALLGEADILTGQMFCPRSPPNIMTMFTTIGIGEDWIIQGVCAYVPQSAWLRNASIKDNILFNLPYDEERYRKTLEVCALVTDMDILEDGDESEIGERGVNLSGGQKARVSLARAVYSRASILLLDDVLSAVDAHTAHHLYHECLKGELMKGRTVILVSHHVQLCAPDANYIVALDNGRVQFEGTREAFQTSGVIRTLMQSTVNEIGDEKEEQVIEEIPVPSSHSSDSDPSSETTTIAPTPATVKMDKKPARKLVEEETRAVGRVSKSVWLTYIRACGSCWYWILFTVAYIIAALSPVAENGWLKQVVWSGSVSDGDHQKSPTYYIGIYALVIVRFLGLIVTTTRWIVLYSGSIHASTVLYKRLLETVLFANMRFHDTISRGRLLNRFGKDFEGIDSSLSDNFGRSIQYALSAVATLISVSVVGGPPFVFAALILGVVYWNVAKVYGQTSRDMRRLDSVTRSPLYSINGETIAGATIIRAFGASSKFLRDMLRCLDTNANPYYWMWGVNRWLSIRFNVLSSCILGAIACIAVFNPAISASFAGFSIAFANTVTNDLLFMVRRFVGLEQSMVALERVKEFSELKREAPEFIEPRPPVSWPATGAIKCEDLVIRYAPELPNVLHKLNFDIRPGEKVGILGRTGSGKSTLALSFFRFVEATEGRILVDDIDIANVGLTDLRSKLTIIPQDPTILSGTLRSTLDVFDEYEDVEIFEALRRVHLIPPSDIPDEDVATVNANIFRNLDSAVSEGGENFSTGEKQLLCMARAILKRSKVLVMDEATASVDYATDELIGKTIRQEFADSTILTIAHRLRTVIDYDRIMLLDQGRIVEFEKPHVLLNNPSSKFHALCRATGKDEFSTLKKLAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD08</accession>
    <name>A0ABQ8VD08_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32632" checksum="47FD806652D86934" modified="2025-10-08" version="1">MPTTKGASSSKLPSKPLELPAGQDGRFTSAQKGKKKTPTTIQRESSFPDLLYPPDFKLDKRPPKEKAGDQDIRVERNFIHLHQLLTLDHSTLAQLLTTLNKLQADFTVFLNNPNHISQLSLPPPSSTPPLPPVPTTPTPVPQDSTHVVTPQTGTCPDLLSRIMDSPSVPVPPPHKRPHSELDPTAPSPSKFARISSPHHLGHSPSAILLAPAWWALPTSPAAIIAMLGRWQTFFDAHGASLPLPDLAECLDTTENGSYVVRLSFTDKSLNTFMRTWKTHQPKIPEIFDVSVTWSSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD19</accession>
    <name>A0ABQ8VD19_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_844388</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="206"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4478588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="277" mass="31056" checksum="4217726526BBB5B0" modified="2025-10-08" version="1">MMAYRENRPDKRSISSLLNPVALNSDVPPPNFSSNDNMPRSHHYAPLVKTSRTEFDRHSSNPDLVGSGLHLPPREWPRNLHNDHRRTSNRNDIPNITSKMPPTRHSPVGSASGQFYGEGYPNGVTSSTAYVSDVSGLPFRNEQHTGLEQSNPMLQAPVYSSSNWEKNPVARNPGGTFHTFSVALRKEYSSIRTSPLVIRPRTAEISPQPRICSACGITHTVLWRKSKVHPGNYLCNRCGLWERNNRVERTTLADGHTSMVKEFIVQSPYSSEGDILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDR1</accession>
    <name>A0ABQ8VDR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_835478</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT XANTHINE DIOXYGENASE XAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="22"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="396" mass="44084" checksum="DF156BDBAFB36F13" modified="2025-10-08" version="1">MAVEFVPLPLPASADASKFIDFGREVRGVDPGSLSPELFEQIKDALYKHDALLFRDVKLTPEQQYALTKAFDPQSENYGHGNNKTEGTKKSILHPDLKTIPRVPQVQLIGNGTVYNHEGLAEAMLKHPSHSTFHKTRVTSEDEAKGITRFYRWHIDAALYDLSPPRVTTLYGINVPKGNHQTCRYDDGTGDELDVPLGTTAFVSGKTMFDILPQDLKSLAVRSRVRYAPHPYVWMAPAHAMSTGLGIESEGLELPLNELPPWEEERRKVLPVVWKNPVTGNLHFQVHPCGAAELIVDPLPAGASRDGALYPDGAHITDLKEVRDLLYKMQRPAIAPKLVYPHDWRENDLVLFHNRGVLHSVVGAFTKEQVRAFHQCNLAASDDPAGPTKEDVEAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE00</accession>
    <name>A0ABQ8VE00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pyranose 2-oxidase</fullName>
            <ecNumber evidence="5">1.1.3.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">FAD-oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glucose 2-oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Pyranose:oxygen 2-oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_834782</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose + O2 = 2-dehydro-D-glucose + H2O2</text>
            <dbReference type="Rhea" id="RHEA:10552"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16609"/>
            <dbReference type="EC" id="1.1.3.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.10" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012814">
        <property type="entry name" value="P2OX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051473">
        <property type="entry name" value="P2Ox-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02462">
        <property type="entry name" value="pyranose_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42784">
        <property type="entry name" value="PYRANOSE 2-OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42784:SF1">
        <property type="entry name" value="PYRANOSE 2-OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="13">
        <location>
            <begin position="297"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="14">
        <location>
            <begin position="501"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4489848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="625" mass="68662" checksum="A451969C2EC9E90D" modified="2025-10-08" version="1">MATESTRISHAEALDFLLDAENNVHSFVDSSTSEQNVRTAGFEPVADLGTQAARFANFGSPEPVETRSCSTTTPPRRRIIQCDVFIAGSGPIGCTYAREILEKCDSDVLRPRNAVYMAEIGAQESPVVGAHLKNAVKYQKDIDAFVHVIQGALQPVSIPVSDTHQSTLGGNSWTPPINSKQNQLVICGQNPQQSREDNLGATAVTRAVGGMATHWTCACPTPHSEETTSSPIPRNELDSLLARARDFVKVDSTVFDKSIRHTTVKDILTTSFPNRNIRSIPLAVQPHSKAESGFVTWSGSNTVLGDIVNDPRFTIASEHRVTQLIVHPSFPGTVAGVLMRDLKTDRDVLVHARAYVIACGAVCTPQILYNSDIRPPALGRYLTEQSMAFCQIVLSKKTIQNIQNTQNPVWQALIAQHRNKHPLDPLPIPFRDLDPQVMIPYSSAFPWHAQIHRDAFSYGDVGPRSDPRVVVDLRFFGKGDILENNRVEFSNKAKPEERPEHTDVYGMPQATFHVVRTDEDRDRDQKMMNDMTTVANSLGGYLPGSEPQFMEPGLAMHITGTTRVGSDSKTSVANPCSKVWGFSNLWVGGNNVIPDSTASNPTLTSMAYALKGASDVIQCLQYEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE32</accession>
    <name>A0ABQ8VE32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_377252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF31">
        <property type="entry name" value="DCN1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCUN1" evidence="2">
        <location>
            <begin position="61"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="284" mass="31843" checksum="B2D6F16DD4B79AB3" modified="2025-10-08" version="1">MSSKSKASDVDIASFCSVTGASYKDAKKFLEKHKRLDAAVDAYYSNPNSFATSTKLQTSAPSTSKINASFDEYKDPDSEDIMINGTIKLCEDLEKDPEDVVLLAVAYELKAPEIGRWTRKGWVDGWKANGCDSLPAMQNAVARFGHQLSTDPAYFRKVYLYTFDLGRTDGARSLAMETAQAFWSLLIPHGLKGGALSHISSTDSDDDVDMNGAEGWRPEYTDWWFEFLNEKGGKGVSKDTWSMFLDFMRSIDTKFEKYDMEAAWPSTIDYFVEFAKERLASSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE93</accession>
    <name>A0ABQ8VE93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1064"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1064" mass="119171" checksum="916DF779E43F4DE5" modified="2025-10-08" version="1">MSSSPFSIYVWSLSRLVNQIVQRLQCARHKLDLCYQNFNNRGTSSLIYIHRLLGHACVSLSLSSQQDEPSRIYHFRTHFMDSKSYLGNPNNTIKADGLFFHDGTMFVYSSPRPEGYGKPKPCVFTIAGRVLSSSNNTGMTGNYVPSKAFAKSGKRTALLGRPYLNGMTSDWDTSISNLKDIISRLTNGDGHDVSYLWQDDDADMNDGAVRFGSPLFRALKPGEARDASVAGVVPVGKENSEFWKDAVEAFTFTEYPAFDINGKKIANKDVQRSIEGATVALDVIIRGWKFKTDKKWGFALDLKRLSVIAPAEDDEEVELPPLPSSQESTASTTATDLSHDGAGGPQVKVKHIVTVGDDHVSADAVGVLDLQIRDSGSVPHPTTNKPQGMAPIAHANANNRSMTRSANKREGSPLLKANKVAKLALKDGQDRDISSLAVVCKHMSSVFLPVLYQRVSTNAFNTIALNRPLFSILTGAHPASYVREVELVPDLRPIKPSVLRAGIRSLDYRVSHPILRSLSIRSTSTVLSDIFPHSPRRFTAEYVSVVLQNGYKNLDKLLNAYIYGLTGFEPTDYSGEEVIPVLINFPHRAFVFEAVSSRMKEKIKSLCYDFLLRSRLDGWLGNDENEYIVHGFARVKMTGVLKHIRIDEPLVMMACAIWLNGSLESSAHSLYKYVANRIQDHNPSTGRNGFEEFICFYLQQVFQKPRRLGQVFNLPDKQNPEKDSALAKKRATLVTLHIDEVGSQRKLTEGTTDIQSIGEAKLPGALGLGVQSMDECVPLTDWVKLKGHTAFCFPMNEMGPDIMCFLKLEDDKGDPEDFTYVCLAIQCKFHQVDGELEPSTLKDAIATVTPRKFFAPRHVKDIKGATGREEKRKSVREGLLSALEGLPRKDPLAGKYGVIRIICGFPVRVDLDTIFYQHKEQRKTPRHILDPDEEDEHPLGKLDVEFLTTETAQLHPTDLLSVIKARAQNEKKKGKSFWSTFDPAILWSDSEEEEEEESQKRQQRMLVQAQSFELDNHSRMIIEMLRSDYARSRGLDLPPRVRKRKHDTLKTDLDLSDYEGDNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE98</accession>
    <name>A0ABQ8VE98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_868580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046261051" evidence="2">
        <location>
            <begin position="18"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="124" mass="13132" checksum="E6D0FE83F9B9DCC0" modified="2025-10-08" version="1">MRFSTAISAIFIVAAAAQKSQPSSVPSTGFLCPTSTTNGNSQIPDLCDTPPHSSSVFGCTFRGNTSSTSTLKCVYDVLTGECTSAEEDCPKSALDLSKRSMPAKRSHIPALPVPVSRKVHRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEE8</accession>
    <name>A0ABQ8VEE8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobic surface binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_372400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046501537" description="Hydrophobic surface binding protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="14599" checksum="FDF8DE28857971BC" modified="2025-10-08" version="1">MARIIFAALFVLLAVFILLVDAAPLKSRQIGDIQCNVARLQIVSDLAETGNLLSKINGNDAATTSAVSTAQSGLSSAGDGIKTIAAALIEGQTAPADARDQTADGLQTALTALSGLNSTDPAVASTLSKLNEAISAGQSVVSDCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFG5</accession>
    <name>A0ABQ8VFG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="183" mass="20169" checksum="000F466CD373CBF3" modified="2025-10-08" version="1">MKERKAAAAAKKRAEEEAAKKAAEEVHRQKEIAAWDLEEWRRKMAEAATTCSRWGSSPGETSVSPRRPVVEIRKEKGKGKAKAQPVGGDPNDGNNGEDDDNDEEQAPCEQCQLKKIPCLEQAIIHNVGHTYLLAAGGCLPSLVAIFSPFVTITHGLAYHPINLQPHTPADYHLLFSAHDHQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFX2</accession>
    <name>A0ABQ8VFX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_764964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23422">
        <property type="entry name" value="beta-trefoil_Ricin_MPL_CNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="46"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="20952" checksum="2817DC7231C92EBB" modified="2025-10-08" version="1">MLFTKFAPSIISVFSLAAYTLAVVMPPRSELESRVYPRATELIQSGSVFTIHNVKADTVVDLSAGDNTTITGWSLNGGKNQQWTTLWSGESWNFQSVATGLYLGIVGTPGNGTNLTVASTPTAWDIWHDTVNETNYRIFVPNTTVNWDLWGYGDATSGDPITLWGTWSGIHQTWRFVQGTQGFLHLDSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG20</accession>
    <name>A0ABQ8VG20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_344091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="71" mass="8053" checksum="95D5491164F3D8C6" modified="2025-10-08" version="1">MSRGPYSGRVCRAFLPTRNHFLNSIISRWFGLVLLPLATYSADGLLAIGHFLRYIVRHFRGQPAQSSILVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG78</accession>
    <name>A0ABQ8VG78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="449" mass="50010" checksum="3E50C57B66F352A3" modified="2025-10-08" version="1">MDVTGDESSVDDEPRTPPAQSAASDPGATPTQQNPGEARTRKATQLQTAKSISKKTARTASRAARSRTPSTADDDDDTGAPLNPAHVAVVSGLSGLNQNVGRLAESLETISKNQSITSQLLSRLEGCLDGERPRSLTRSSSHRRPMNTNTGHADDTQAEGSNQNAASAKGKGRMEVDEEDDEEDDDEEVEYVDGEDQAEEGIALKKKRKLTKTRKALDLQSLVVTVTDEDAKTFEETFTQDPLAKPCTVNDFRYYINGKPSAAWNKGAAFVFVDYVKQEKLMKIPNKATHDLLRKGFMTRQEVLKEDIWIVGMSSDEEDKEGPLSVPPQYKTTRPFWRGEDLEEFFILLDACHILIRMRNESPTGTTYSQGAPPRYRVRTQRESENKSFVKGLPRNFYRAGWLEEKEPGWQKGGEGFVNMIICPKPAKELVFPAELKEELKKNGYVFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHQ0</accession>
    <name>A0ABQ8VHQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_829162</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045199685" evidence="5">
        <location>
            <begin position="28"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="98"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="455"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="497" mass="51005" checksum="F2A49015F6520903" modified="2025-10-08" version="1">MTRISLSLSAFSLVQLLLTFTISGVTADPLHIPVHRKRSAPRDVHYYAAAADRVRAKYGFPTSDSSKKRNGASISARFGKRASSAGISITNQDDDASYFATLSIGTPGQSMSVVLDTGSSDLWVTGSGCQSCNTQTPTFDSSKSSSFKSSSSSSSSSKGGQTTIQYGSGAVAGALAQETVELGGFTVQGQTFLLADELTSGLLDGPVSGIMGLGFEAIASTDSTPFWQALVNAGDLSSPEMSFWLARESSSSSTTTVDGDTEVPGGVFTLGGSNTSLFSGNVEFLDTQGTPSFWLLNMNALTVQSESVSLGSSSQLSAIDTGTTLIGGPTDAVQNFYSSIEGSSTVEGQQGFFSFPCSTSLNTTISFGGTAWPISSADMNLGPISKDSSDCLGGIFDLSLGSNIPENSGNPAWVVGDVFLKNVYTVLRGTASSSSDTPAIGFAQLSTSAGGSGTTTGNADSGSSSSSSNGSLRSFKRMSGMVLNGFILLGVVPSLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHU2</accession>
    <name>A0ABQ8VHU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alginate lyase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_882071</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047047554" evidence="4">
        <location>
            <begin position="19"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase" evidence="5">
        <location>
            <begin position="233"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="622" mass="67228" checksum="6EC0BBEDB34F372A" modified="2025-10-08" version="1">MLSVSTLCVLLVVHRTLADPTDFVHPDYVLQHIHDSSTDSAKASITRNAQAAAKSGPYSIVNSNGVTAPSGDKHDYLSWAPYHWPECDWCSTGRTHLVHSGDGGNGTNAGPDDPPPDQDLGPGEDTGDDYDYDDASYAQARSLHVDSILELASRHNRLLRIRRTAPKEESFSSSVPPATDSVLDVLPLPQAPFGTLSSMPTAGLSTGSLPTPTSHATSQHIAGSSTAPQAAVQTSKSSKSACTPSPTKSLPPSATWTTCPYVARDGQVNPDVRTLAGASAINNASDGFLSNVLASLFSGNRQYLKAAINILNAFFLNQDTRMNPNMDFGQVIRGPGNDVGTFTGPLDMRGLVKVVNAIMILKRSNGTDWTSELDQQMQTWMSHYLDWLQNSEIGKKARSRPNNHGTFYYMSISALSIALNKPQDAVNAMEEFFGTTFQSQIAKSGEQPFESVRTRPFHYRCFNLEGLIVLAKIGDYLGKNYWNTKTKYGATIKTAIDFTMGVKPGNEDIEELVPHVAAAMAAYGPSQAYTNFLSKESAQNQPFWFYDQPSALLHAPASKAGSSKRSTVVWGRGDDGVTGPVDPACPPIFQEHGRVEIDNGIFVTCQELLPAYLGRAEGAVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIJ7</accession>
    <name>A0ABQ8VIJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_762765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="255" mass="28156" checksum="7B2107AA3026CC0C" modified="2025-10-08" version="1">MSRSPVEAPQHVLALLNKLHKLSIEQEDRIKGDKARFVSTDVSNNADGEDGVTPHKYLNNDSKSKASLDDLMRDKFIALDEDKCHFVYQLIRAMDATNVIEAGTSFGVSTIYLALAVRQNKKSRDGAKVKPGVIATENEPSKAAKAREHWAQCGSEVESEIDLREGNLLETLATDVEQSVDLLLLDIWTPLALPTVKVIQSKLRPGAVILTDHTLTAATGYKELLDYFEAPDSGFHSLTLPYSGGFEMTVYNPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIX6</accession>
    <name>A0ABQ8VIX6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polysaccharide lyase 14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_919545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048958">
        <property type="entry name" value="Polysacc_lyase_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124:SF1">
        <property type="entry name" value="DISAGGREGATASE RELATED REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21294">
        <property type="entry name" value="Polysacc_lyase_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046261056" description="Polysaccharide lyase 14 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase 14" evidence="3">
        <location>
            <begin position="215"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase 14" evidence="3">
        <location>
            <begin position="513"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="58661" checksum="E145099E0C8A52C6" modified="2025-10-08" version="1">MTSLFLATLGVFIVISCPPSLSAPIIGSYPISNLSAETVYETATIFTTETVQNIMFSPTPTSFRTYPAPTVEIIDGKILALPPETTSTITEFVTAIVTVLPISTSTSTVEVVVTDTVTPSTALPATTTVDIVTVTVVPSPSKPTTWTAPAQMTDLSAFNITNFAGGSQNLRIVDNLSTNSSTELSNSSAPTEVVTFEVSSDHSSNNDSLTVWTNATSALQILYPENSIDPARKPQGGAEFYAAPLELKDAKNVTLEYSVFFPQAFDWVLGGKLPGLYGGRQGCSGGDAAVDCFSTRLMWRKDGLGELYLYAPKDKQTDSLCNDPQSVCDAEYGLSVGRGSFVFAPGSWTHVRQTVTLNTPGQQDGCFTLEVNGNTVIDRNDVYYRGAPLSSSPPSSVPSNVDSRKTVPKTTGSHTSATSATSPARVHQPQPSDSGDLFGPGGLLGGILKRANQEVVISEETDGKQQSLRLNTSNADTVPNDNVDNGDHDNPENLSLPLLGNTLQGHSTTSDQPPGFIGLFFSTFFGGHEKQYASPKDQLVWFKDFAMSNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK49</accession>
    <name>A0ABQ8VK49_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_946428</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="201"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4496753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="694" mass="75787" checksum="CD8EFEF29797A112" modified="2025-10-08" version="1">MGPLTEPSILTEKLLLELRNSIRGQVYQKGESNFDEYTLMFNGNVEPNGQVVTCPLDAEDVSRIILFCRKHAFSPSVKAGGFGTAGWAVGGEVIVDLSRIGDVDVEPPNEESSYTSIRDMAPSNSKGKKPEIAPYDVNPGKRRREEDDKLRKYHAASGSVAAFLQEPSRSDSPPPNVRRRLNESTEGSHDNISNTNIEVVQSPTPDSNVEASDAQNARSAHADDNTDSSNAPVDADPFGYLEERHPSGYSGRSNLQSTSRTLYDSWGSGSRSAGSSLAITTAPAVLHSIPSQTQAIHSHAYVTFGAGMRQKEIDTFTANNPLRAQSISGGQDTVPYHVPFAAHPAGSSIMLLGGFGFLGRLYGLSIDNLVEVEMVLADGRIVIVNKDEHPDLWWALRGAGPAFGVATRYKAKAYPIPVVFAGNLIYRFHKATAASLIKHFRDCIKNAPRELYANVLLTAGPKGKDSLVVIQMCYVGSREKGQEYLAALASWDGEKSLLNEVHEKSFLHQQDSVAQVLRGKAGRQWFIRSALINSLPDDIIHQTVLKFDDTPVGCTWLFELAGGAISEFEDTCVPKSQRETLFTVAALHQWDMGINDPRCITTAEEWIAETLKPIQTGGPFPSFLGRHEAPSRTISAFGSNWDRLKELKKTYDPTNVFRNSLWPLDSEGNIVEASTHEPATPSAAGTSFEVLSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKB6</accession>
    <name>A0ABQ8VKB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_824957</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lipin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031703">
        <property type="entry name" value="Lipin_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007651">
        <property type="entry name" value="Lipin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16876">
        <property type="entry name" value="Lipin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04571">
        <property type="entry name" value="Lipin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="6">
        <location>
            <begin position="927"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="465"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="605"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="731"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="849"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1204"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1204"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1218"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1228"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1270"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1325" mass="145494" checksum="FE06EB2BC3ED2CCD" modified="2025-10-08" version="1">MNYIRGAVNAISAPYQYYKDINPATLTGAIDVIVIQRPADNGGTELACSPFHVRFGKWQVLRPSEKKVTVSVNGHPIPFDMKIGEAGEAFFIFETEDDVPEDLITSPLLRPSSPANENTRASIDVETTRFGTKKAGDQTPDADEPEPLDLNALPSPAEDDVQFSPGVDGDNNANTSSGRIHTPTTHKPSASTSNFTIPSVSVEPHHIRRRASTVSVSVSIPHASSLPSPPPSPTRTPAGKAQDACADAALQSVAEIQVPEIRYQDGIALDTAGYHSQQLPQTPSSVSTKKHDSSHDRERSDRTIRGNDDVDDTTLYAFPSDSTRKSVSSMPYVTHTQSQPHVIDDAPDSESDVHQDDTLPGGDHGYRTAHSNSQSKSLTLPFPSRATTEPPPDLPFPSPSSSAPNSASPVSLTLKRFPGPGKLNVLSPVQEYSWEWGAFPTPSPMKSTFGKGGRFESGLGTIGPEEEHDSFTSSEPHNANFTSSRGRTIGSGIRDSKGKSMLSGLSSVNPDDEVGNMHGRSMSVPPGFDESPTRERQRESLLAKYNDADAAAEFTGQEDKLDAAGGFGSSGKLSVSKSDPTVFKLSIEGKKVEFELSLVEYLENERNGHDSSDVEGESDDHEEPSRGRQSRNLRRFSDNMRNRNHFRVFSPDGRWPGIDEFETARLFEKGKISFEDFIQNDQLVRDPRLVLKWTRQQFISQRDGSPLMDALAIWRDSYILRKGKRVSMRPISPTSALDEDQEGSAQISPVTDPEGKKLVLERSKSEPPEEMKGPSLGGVKSPPPTSSSWAQWWRRSRKSTNVPSATNSEGSSDKIARPEMKEAFTAPSGVPVSKLLEVPVLRDELITGSAPALPSTPVHQSSTEPERTPAFTDSSSRKYAKTLRLTSDQLKSLNLKPGPNSITFSLYMSGVVACTARIFLWDSTDLVVISDIDGTITKSDGLGHVFAMIGRDWTHLGVAKLYTDITRNGYKIMYLTSRAIGQADATRGYLKGIKQNDYQLPEGPVIMSPDRLMASLHREVIMRKPEVFKMACLRDIQRLFGEASRNPFYAGFGNRITDALSYRTVNVPSSRIFTIDSAGEVKCELLELAGYKSSYIHMTDLVDQMFPPIHRKWAPEFTDFNFWKPPMQEFPLPDFSPPSPALSARSDSSTFARIRNFSLVGPRQNNIPKVAAAVAAASSRASDDEQPLRNMKLQQMSSFERLSSTLGFSGNGSSSSILKDRRSDSPDTRSYSSSSYAGSEDEDDDDGWNGGRRERRRSTTSMPGSLEDMNFGDDDEEEYVHDDPNDDYNGEYDPHGEDEVDEVAADDAFDEDLLAAGEMKNVPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKF7</accession>
    <name>A0ABQ8VKF7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial outer membrane protein IML2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_763054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="745" mass="80423" checksum="1B2E5F00AF859851" modified="2025-10-08" version="1">MAYSPNAVAIHLLSASRGFDHLFADDIPSAEKVFASENDPFHIVGSGYLCFLEASLGLDSSKMGEAARLLSLAEAGSRTALKAAAKSKSRFASTAFPPGLEYEIANADTVVLLGVTHALSESYMGYLQCLYSMNSAYGKFSKLYKTVFPNGLDSYSTPLTPLSPFSTPSSAGSPAITSSAFITTKPNKPTRPPVRQSSSFFSLAGRWGLDSASSSASSLSLSVEAEKPEEIQNLKSLIIAGTAFGFGLFNLIFSLLPKKIQSVAGLFGFAHDRRLALQALAVSAEYAAEGEVHGVLAGLVLMTYHGTVLLLSGYQADEARIIREYEGVVRSIEARYPTGALWILNRAKIYRMTCDPESAIRVITSGLEERENDAEGENNKGCKQGDSLLLFELAWIHLSQRHYMESAAAFLKLTELTGWSHGTYYFIAAGCHISLALSENVLPYEKENHLNKAQGLLDAIPSLLDKRKIGGKELPTEVLIKKKLAFYKKKQKRLGGDEAKFVECIRISPAEEMGIFWNTHNLISPSLAKAHIKEWSALSPPLGIDSPYMADPISSTTLDLDTPDELALRFLLLGIAHRSIGCVGIRIKGNSPPSTGPASSSSSCIDSPGSEPESIVESASSTLFDELTPYADNASACLRASRELLSAAHALQSSIKVSTWIGGLAMFELAVLDLKEVEVEENDGKGPLADLGQRWKTALESARIKLDAAMNLSPHSIDLSSQLDIRVSMLRDEIDMKAEMIGLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKR8</accession>
    <name>A0ABQ8VKR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD-P-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_824188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF7">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE (AFU_ORTHOLOGUE AFUA_2G00830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="333" mass="36118" checksum="0940630836F77028" modified="2025-10-08" version="1">MLERPAISSNLTSRNGSPLRPAFSSTASSFKPDSASLGDDVHPIINEGRVAVITGAASGIGRAAALELAKLKLKIAIADVDEARLQQVGKDVAAIVGDANVLVVPTDVSKLDQVVHLKEKVYELWGEVAVLMNNAGIGLKGTSWDGINNWKTIFDVNLFGILNVQQTFVPFMLHQENQGMIINTGSKQGITNPPGNAAYNASKAAVKSLTESLAHELRERPNSNVTAHLFIPGWTYTNLTGALTQAEKPTGAWTAEETVLYMLDKVRAGDFYVLVPDNETRRELDELRIMWAAGDIAEGRPALSRWHKDYKALFEEYVRDGMTGVGAGSERSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL58</accession>
    <name>A0ABQ8VL58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_228654</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="145"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="556" mass="60821" checksum="564C71B112862018" modified="2025-10-08" version="1">MFSSNKTRDRIISEDVENGEASRPLLGDHNVVFSVDDDSDEESLAGPSKTEHSVRFQEDVQVIGPPLRSTTASREAEYELDSDEIDDEPEITSTPRGHMSPNMPLIVGLLDSSRRSFDSPLPLNDANGRDLDLEAIAAKRTAGGGLFDSIANMANSILGAGIIGLPYAINQAGFFMGFLLLVVLCGVTDWTINLIVINAKLSGSHTYIEIMNHCFGSSGRAAVSFFQFSFAFGGMCAFGIIIGDTIPHVIRSIFPTLYKIPVLGLLTNRQFVIFLCTTCVSYPLSLYRDIHKLSRASGLALISMVIIVASVLVEGPGVPSILKGDPSMRFSFVNAGIFQAIGVISFAFVCHHNSLLIYGSLRTPTLDRFAQVTHVSTFISLVSCCTLAVSGYVVFTDKTQGNILNNFPSNNTMINVARFCFGLNMFTTLPLELFVCREVIEDYFFPHEDFNPQRHLFFTTTILFSSMTQLVDTVAMITCDLGVMLEITGGVSATALAFIFPAACYLKLSNQSLPWYSRNRLPAFLCVAFGVIVMTLSLFLALKKSWTKEGEATICM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL82</accession>
    <name>A0ABQ8VL82_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_823490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="4">
        <location>
            <begin position="123"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="27567" checksum="EB50D5C1435F116B" modified="2025-10-08" version="1">MTEGNQSEALHCLQRLIPTVMSFIFKNAVSTAGRRAAFRPPTGVLAYRSLHTSKPSTAQSPAPLPSSSTDPANPITQIANYNSNQHSLENPQNKAEYVLSTLDKVANWARQGSMWPMTFGLACCAVEMMHMAAARYDQDRLGVVFRASPRQSDIMIVAGTLTNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGMLQLQRKMRRSRKGVLWYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMT1</accession>
    <name>A0ABQ8VMT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_793098</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF2">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="5">
        <location>
            <begin position="136"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="482" mass="52393" checksum="BA9DA50367B4AAE6" modified="2025-10-08" version="1">MNFTHGITHTPATVKASSKAITLAHIKASTELKYVRLYWVDLTNTRRCRVIPRDSFLQLMESNRPGVNVGQVALGLVYLTIAEGFHPISEYLYVPDLSSLRILHGVGKSPIFGILGKFENKSPVGEKSGVEVEMCPRTTLSRIIREVRTNCSAEFLVGFESEFILLKSTNPVVSMNVHGWSASAGMLNGSIEAEIMEEIADSLQASGITVELFHPEAAPGQYEVATGPLPPLEAADALVYTREIIVNVAAKHGVHATFAPRPFMYSAGTSTHAHISVHDIPNRPKFRKAPGELSLLEKAFLAGVLSHLPAIAAITLPIPASYKRAVDGVWSGGTYVSWGTENREAPIRLTNVASPNSRRYECRFIDATANPHLALAAVLGSAMAEMKAVSDGSGDVQLEVQDAGTKPAAVMTKEERKTHGITKRMPASSGEARSYLRGDGQLCEVLGKELIEAFLSVNKTLEDALMQDQVEDEQVTRLVEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNL0</accession>
    <name>A0ABQ8VNL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_219663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="596" mass="66419" checksum="EAAB0E76465E132E" modified="2025-10-08" version="1">MRWLAPPTRRELTLLLFCSTVFTLAYNFENTLRYVGFDAYSTRGALLTRFGFISANTVVGTLLKDGRKVGDLRDQTDNTIIWNGEDNKIIKIYSESKGAYAEYGTIEAGQQLGVGAHSAMWISQARLEKLWPNKLTAKSVKEGFWRWNGDVPRTKLIRHLPGYTVLDQPIVLNNVIYIVTDKPQSFPELSSITSSMLDNMQVISTQQARIVLGKYGGRIHGVSWMCTEPAPQDTALLSLWSMHSSIDSSPSKISPSLLPNSLSPARLILPLTPTFTDSDNDENGNKKPNFPFNYGERDILPPGSPPRPPVIPRSRSHTGIHPLLLKIALPHMPGVWYKEDWDDYMGMEVPYVLERVVIGDYGVQGIETLLQQHSQSGTRDWWEPIRKTVVSFFQDPSEIFLDLIDNSRKKTLTYVHRPNSLVAEDHNALVRALMKMGREKGIEVNLVDAGASDGMHVEKVNTDDVEWGTRMGAITRSDILLASQGSDILDGVFLRPSSPASTSIMVEFFAPSNSRSNEGEAAEVAFPGAREHEVVAKSLGLSYIPWVKDRRLTSDEIANSHTLAPDSIPQSEHNVPVDANTIAQFLNDILESFSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNT3</accession>
    <name>A0ABQ8VNT3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_792387</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPL family. TOM1/PTR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14297">
        <property type="entry name" value="UBA2_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010309">
        <property type="entry name" value="E3_Ub_ligase_DUF908"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010314">
        <property type="entry name" value="E3_Ub_ligase_DUF913"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06012">
        <property type="entry name" value="DUF908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06025">
        <property type="entry name" value="DUF913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBA" evidence="9">
        <location>
            <begin position="1263"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="10">
        <location>
            <begin position="3262"/>
            <end position="3597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="709"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="952"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1310"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1674"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1727"/>
            <end position="1761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1982"/>
            <end position="2166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2413"/>
            <end position="2488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2511"/>
            <end position="2542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2893"/>
            <end position="2956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="716"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="952"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1310"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1348"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1691"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1727"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1993"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="2004"/>
            <end position="2013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="2044"/>
            <end position="2117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="2125"/>
            <end position="2159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2413"/>
            <end position="2443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="2444"/>
            <end position="2460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2461"/>
            <end position="2482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="2522"/>
            <end position="2542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="2895"/>
            <end position="2924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="2946"/>
            <end position="2956"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="3564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="3597" mass="398275" checksum="F68CC5EBECF42189" modified="2025-10-08" version="1">MKILHKSKRTVPPPPQVADLITRLINTPDDALAQTLEEIDAWKWQRSDLNAWIKVLNKFDTVLEDVIREYDIDKLQVREFSTESKKMVSEILKFERLLLENSTNRKMFNSYDRLNSFLFASDLDVLILALKLLLRPSQQYSAQPAVSQALNISTPRLLSLAKRWPHLREYGIDLVDLANAQGSLEIDALPNEAREVDFSFYRKDAGSSQVKPEADPNDLSSSRKLSSTTPIAAGAVAVHLDEQTLRSKTAMDVLADAIRTHEIPDSEKFDLLCRIRAATTLAKGREAEREKLVHVRLLSIAIFGHTHPESQALSTLFLFEPDLIPHVAELLQVGRGISVHIQTAAIAALDAMARYRSKVHEVLTSVNAGVNHGILMGLLRKTISDISSPDCKIPHSFVEALLSFVTFIASHASGGNMIVGAGLIPLLIQILENRLPTRLQVVSKTMQLIDNVLYSFANAFTVFCSSHGVEALVDRIEFEVDLDIREHGDQQKSRQIFGSHGELPVVRAAVLKHILRSMHRMMQSSGTLEGLRGLIDMSILKSIKKIIEYRGLFGPSVLPIAINIMATFVHNEPGSLTVIQEAGLPETFYKSIEIGLEPAIEVLQAIPNALGALCLNEVGQSLLAAHPSIIPAIFSIFTSDRHLKILLEKENAVLIGTAVDELIRHHPFLKAPVFQALKSTMAKIEELGHAYVPPDDIRNWYQLTVARPSTSSTSEDVDKMEGVESSEGKESSPPPPPAYTAALLEPHSEEAMRLHENNIISFIDILGRFLEGLFQHTPHCRDFISQTNGLVCLGRLTALPCLPYDFANSVASDSMVQTMRTLTEVAMSETLQQMSQLVKESLQATQEFWSDDTEDSKLLSLLDVTDEEYVNKNFYFRNLITLHVRVTLLSDVFSTAGYAHGRGAISLLQNLMTSTTPQVIADLGSLHRAGIWENIVLKAALAAKGIEVYQTPSASPLDQSPNHRTIDLPVQGPSVPASAPNGAVENGASTSTSTPTKETHTRHAGPKEFNATALKHITHGIPTALSPFFQAMVKTFHSRRTPEQSQKKQMIESSATVADVLLKHLSAKSDIEDKSTLYIYYGIMLGLVTVLLIDERTTNHTIYTVQLLAFYRVGGVDAVLNVSRSFISSIRSIVPIREEDRSPAQTQELLHAFSGLKIVLHLLHPLVSSKPLFESGQTNIVVTKDKKDTDDDYFEPHNFLVRLRLAVLPLLQEIWESSWLIKAPLGVCRSVVQTVLEVLNSSDESKASIETGPSSSTFFRSNVLDESRIRQLTDMGFPRAAAEHALRRTHNNVPAATEILLANPFLPFAAEPEPEPATTASGSADVVTDESSVNEDGAGSGPTTMPAEPVESSSPEPTIGKTVEEWRKDLEAAREPLRAGISRKALSLVDEHISLLFDIHTAFVRPGDAHQPEAIRNIVDDIKGFSPYAYDVQEQPLANRCRLLALVLSETPYSLDSELRNSLMDSLLALLLSNPVSMDPENPVIPRWLAAHLLVTEALLTLSEEPRNISTPKEGEPIPSEPLSTGPVLTDARAMVFDFCLKLLAMPDLPSDELLSSLRLLVLLTRDHEYALQFVKKDGLGMLFSRLHTSPVTGSSSYIAIILRHIIEDHKTVQGIMHQSIRRYFTNPRNRVPDVSSYLKNCSAMALRDPNTFIEVTQKLCHLGSPYATSYTLSLNKNSDVPPKNEESKNTVDMQVDPSTADSSESVDEVMYFLAAELMKAAKALSSDAPPTTSSAPSSVVEPHTAPDAAHVPGSKDSADSSKDKAQHLYMCFLMQCMTELLFSYDSCKVALLSYSVKKRTNTPAKENPHSRFRTSTMHFLLSELVPFDGLNPPNGPETRSKMSVSTWAMSLLVALCVDTSSGQEGRDISNDLVAVRKFVLESISRAIKDASPAESTELQYGRLFALSDLCHRLLTVRFSPSTRKHEDGPTQISKVMLEKNFVATLTSTLSDIDLNYPNVRTLVVAILKPLELLTKVAIKMSRAPGKARESSSPKTGSISPLSSDEEDEEEETQDAREETPDLYRNSALGMYGGEMEDMTYHGEDEDMDDEEDMGEHDEEMDFDEETGSEDTSNTDEEEEADEDLDDAEEEGWEEEEDDEEDLVPDEVDEGHEDEEGIVNPHEPVDEEEIEEAEEMMWQDIQDDVDAEELREEDEDEDSGGQGPIQIIHEDGEELDAGSDEDFGHDLDLVESGDIMRDVFNFGDPTGSAPSFFFPRRHRNPVEDHAPMFGRARSGGSAPPEATTHPLLLDASSQAARPTSSTFRGARNPQRIMAGGTTELLQTIEELVGGGAVQLFHHIMTRGRGGGGAAGGVPETIRLDVPAGAIMNLGRHYHLPHRRPPVISASVRMERNTRTPPASSQARTLDPLLTLQRWAEEVKVLHGDLVADRASKLANHLVNTMLPNAIEVARKATEEEAARERDAEAKAQQEKEEEDRKEAEEKAQTQISVESSDQPIQSPSKTEEAPSDVHHPDPPSEDHPMEDATSSVGVSVAAVPEMADTEMVDGTAVTGLQPLEPDQSNDDNVTSLPSENEASASGQVNTTNRVTVMIHDNEVDITDTGIDPTFLEALPDEMREEVLNQHVRDQRAARIERPADSQISVEFLDALPPEIRAEIIQQEAMERARHSAEVAQSASGVPRVPAEIDPASFIASLDPTLRQAVLMEQDDGFIQTLPPHVIAEAGNYRTAQSRRLHVSSRGVRETSGAPAIARKFAPQHDAIQLLDKAGVAALIRLLFFPQVLKKTLIFKVLVNLCENAKTRTELFNLLLSILQDAIGKQKSTSDLITNLVLPGGHTEAVPDLIAQRCLEALTYIVTANSSSSLFFLTEHELPAGLRRASSKKGKGKEKQIPQTHYPIVLLLGLLDRQSLLRTPSIMESVVGLLATVTRPIKEAKLQAQLQPSTSKSVRNDAESSNNQTTSGTDDNSVPTVETTPAPPPSLPHDGIASHTPTAQDPSTEMTLQAVEQQILLSNPPQIPHAVLRLIVNILTVGECSSRTFQQSLNLIQHLSYIPDTRDVIAQELKSKAQEFGHTLFSELDELASALQNSSETQLSSVASKFSAASSIQAKLLRVLKTIDYMYSPRPSSVGVGANHENEDTEKVQAIYESFRFAPLWKSLGDCLAIIEEKADTEHVTTVLLPLIESLMVVCKYVGTNSSANRALRATSSPRSPTTPKESMEDLFVNFTDTHRKVLNVMVRNNPSLMSGSFSLLVHNPRVLDFDNKRNYFTQQLHRKPHAREHHGTIQLNIRRARVFEDSFQQIMRKTGDQIKYGKLNIRFYEEEGVDAGGLTREWFQILARQMFDPNNALFQPCAADKLTYQPNKNSWVNPEHLTFFKFVGRVIGKAIYDGRLLDAYFARSLYRQLLGKPVDYKDVEWVDPEYYNSLCWILENDPTLLELTFSVEADEFGVNRIVPLKEGGDAIPVTQENKREFVQLSAQYRLYSSIKEQIEHLSAGFYEIIPKDLITIFNEQELELLISGTPDIDVDEWRAATEYNGYTSSDPNIVWWWRALKSFNRDERAKVLSFATGTSRVPLNGFVDLQGVQGVQKFSIHRAYGESDRLPQAHTCFNQIDLPQYSSYEMLRQQVLFAISEGGEGFGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNY7</accession>
    <name>A0ABQ8VNY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_901115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="759"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="582"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="639"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="786" mass="86238" checksum="DE5DC221EAF4DB22" modified="2025-10-08" version="1">MTSIKTESIHELNYPRSTSPTKESLRPNAHPYAIKTTSTALLSRSNSSSRTHDSSHHHYVPRTPPATSLGHRKHEGAHYRHRYSSSLSSDNIPRPLPVPPSPTKEAVDDSSGKHPRTFFNPVIFSAPLTLEDLPPNPKLWTPSQLCAYLSTALRVKSGESLQLPAPVARDIASFVRESKITGRIFLRLDEKDLEAYGVNKLWKNALLKTSQNLRQNVLKGQIWGFVDELEGTSNGINFPSAGDAHSGSIGEEEDDDSTPHRRRRSASQPQTTRSRFIAGSTVESSFNHPFPNGLPIYSSASSSSSSDDLFSLTGISPSVSFSTRSTSSNRYTHDNRSRHGRVKGMVDSFERSSSFDEGDPTSAKLLHEIKGNRELDLEKLRKIRRERSGSTSSISNGSSGSSHSPTSSSDDGSEPGAFVGSPVEEYNVSTITSSRPLPDPPRSETDAILLASGLEEPSIEELLAQEGRLEDANSSHPSLTTLTSTFKNQTPNFAKGTFSISKGKGRAKKRGGVYAWEEEVEDLGAAAPGKTTAKRVFSQIPIPATMMPSASSAQDSFEDLENVNGNIREESADQLRSVHISSPAPVKSGQGSGTHTPSRPLPEIPLHPSLVALPEPGDISFSPVSPKETDEETRLRASIAEVTELLQAFEVRLADVERKVDVLDVELKELEVANSIRNKQQAEDTVQINDETEQMTREDRVEEVNEPIFLSEWPMMRKVIDRVFRFSPTGQPPSIGSRIFHSQYWRSPSHINPQTLSQLPPYVLLVGLGVCAVVLKVVARRLIGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP22</accession>
    <name>A0ABQ8VP22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_757672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="45938" checksum="7EEA499C95CD61F8" modified="2025-10-08" version="1">MSLVLPPNYFPTSSPPRYSYLLPEGEETVEFTPRGNAPTNVLVNITQTCSFLTIILKDQNPAEECPTYGRGSTIHGEIGLRSSASVLSVSIKLKGRLRVSISDSGSATIPVVSESAVLWSQDSAHKIICPSVLPFSIVFPTTFKHGDRIRSIPPSFSEAYYQLPAISAQCSYILKVTIHNSSKMAFWNPSRSYSLWLNYRPRTRPQRPVYHLDRFLATLKQIPEDWLESESTMRIRRTDSLDLKPVSCRFFFPSVGAFGLSDTIPFHIQISSSLASLRLLLSSEIPNSGTERPSVRVFITRQTVVEVNTRKCWRTATLVEGRVRAIAPPIYATAVEGADMYVDWEGEVRVEKDMVQYGGFNIGTVVVKDYIVFAITPPNPRSCPLLAHQHSVPIKLVTDVWTDGSTSHPLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ58</accession>
    <name>A0ABQ8VQ58_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_756918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="20244" checksum="C64AE4F322B68769" modified="2025-10-08" version="1" fragment="single">MFEAFPSPFHDVLHTNYAASATETQAIHALLAASFDELSNLAEEIDSAQKTLDRLVSRHTLLKAHVDAHLALTSPFRRLPPEILSEIFIQCLPTDRNPTRSLTEAPLLLTMISKDLRELALSIPQLWTNIHVHLPQCPSNGQVDVDEMDALIHRRREGIEAWLNRSRCLPLSISVHLSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQP2</accession>
    <name>A0ABQ8VQP2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zf-MYND domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_759512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="240" mass="27944" checksum="7803A3AFEB6F15B6" modified="2025-10-08" version="1">MPANVHYTLAPYCARCISRDTSRRGSWCGCGSVFYCCSECLTRHSPVHRPMCRPFSPKEVWGIKIIQNWNDPPRIGHPADYFRHELCRVDPGRSTTHPIFERGELCPLTQRIGIPLRIYRTSLMRESSTAGPNEIAVKLRVDPSNGLAPARWRLTDHPGECIVIREDRKPLTRELLETIYSFIVHFMDYPIDDVEQESWARWEGLLNPSVWHFFARKYYQKQSEESGRNAFHYFSPLLCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRJ3</accession>
    <name>A0ABQ8VRJ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_79229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4498998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="185"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="38422" checksum="534F682AA2E4C3B1" modified="2025-10-08" version="1">MANYTSTPYHSSINHASAYDGIPGAVLLDGILQSFLLGFVIGQASKYFSAFKDDRWQKRTFVGVVVLLSLLQTIIEEYKLWQISVNKSSWAHSHFVWTGVAINGCISWLCETFYIRRCWKMTDHNPWVLYPLGTLSVTVFIANLIQAVSLPLVVNKTDPESGNYIGSGPLMSLLQFVFSYWIFGSLVLDLIVASILITTLWRAKTGLEDSDRVVWSVITLTCESASLPCISMIAAVSLYHSTKESNLVLFFVLLAGKLYSYGLLRTLNSRDGFRLRLNSHNLGRATLSNWKWDQGRGDDHPHLETAVASISETQPPPLHMFMKLFVTRGVPMKFLPMMSPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRU7</accession>
    <name>A0ABQ8VRU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pantothenate transporter liz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_876913</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="517" mass="58451" checksum="C88833DDA3EDA671" modified="2025-10-08" version="1">MTFWQKIKLYIWDSDAHLKSRFERRLLRKARLDFGMLVIGCLGFFMRYLDSANLANAYVSGMKEDLLMNGNQYTYMGTFYTIGYALFQIPGTLAVTRVRPSLYLFVNEIGWGIFTFAQTGAKTYNQMYAFRFMVGVFEASFFPSILYLMGSWYNKHELAKRIAIFHLSGSLGTSFGGYLQAAVYTTLDGVHGIDRTHMLVNYRWLFIVCGCMTTPCAIGLLLVLPDLPSNTRVWYLSQEERKFALERSIALGKSQPGEKELNWTLIKRMLLTWKWYGLVLGYVVYGSSCQNTSYFAIWMKSAGYSVVERNVIPSCSYLISALCIFLWGFGSDLTGSRFAFVFGPLFYGLLPTGILAFWPKNKDLILFAFMTGGVQLMTAVFYTWANELLADDNELRALTISSMNGLQYSVAAWLPIVIFPQTMAPTFRRGFPGTFGLVIAGLVSRDMTHVAGLSHSPMQIIIFGIKLLADRDERRATSLRNSTAFNPAKAKSMSLGDAPFTQEEISFEKELPVVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRY0</accession>
    <name>A0ABQ8VRY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_755287</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="560"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1109"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2264" mass="253450" checksum="46CB27AF34482156" modified="2025-10-08" version="1">MDLPIHVSSALEAHYDPDEAELTCSWLTRNASLRPDAIAHEIYSSVNSDPEMLTYASLNEQSNRLARWLVSRGLQREDKIAVCRARDKYFYIAHAGIFKVGGCYVSIDPELPEERKKYIADDSGSKFVLTSADQAPYFGELAIVLDDLAVQEEVLGHDAADICLAELDSLAYLLYTSGTTGTPKGCLLNHRGLYWAIIAMCKLPSKVTNPDTDKRLGLASIAFDVHISEICQSWCLGIRLVSGPRYEFLANLQENIINIGITHLGMVPSMIEATLSSPDDLPLKYLVSGGEKISDGLLRKWATSPKLILANFYGPTEATIGCTSRQITINDRKENIGRPFASCQAYVVDSAMNIVPRGTPGELVVEGPLVGVGYHKLPDATNRAFLEWPRPGCRCYRTGDLVRLMPDNTLEIMGRIDTQIKLRGVRIESEGVSNVLLSASPIPMDATTLVSLHPGLGSAEVLVSFVAVLNPNITFFQRRSELPVVTDEAFSNSDTLQNMRDAAIRELAVYMRPSYIIPLNFLPLNMNGKTDNKILSALFKETQLQDLIRLQGQAFAQITSDLTSEEAQVIEVVSRVTGLEPGRLNQLSNLFESGLDSLKFTALASELRKTFMASVTVAELMRNPVVRDVARLIPRNDPDYPSGDQTNIITEFAEKWKSVVDGIFEPSSIQAVLPPFPVQEGILFRCITSPHLYVQHFMYRCRKSVDLSRMKRSWEAVMRRQEILRTCFIFDGTLLQVVLHDGVNPLPWQFSDYEDKESSSFPDWFLRDQASHVSTRINEDFTTPLFAIGIYRNLSDKEVYMVISINHALYDGFSMPLLVQEFRQCYLDEELSEPVPLVHMLHPILCQNNEDMRAFWISQFKDVDLRARAIRHPSSISPPSFLSHALDVPLSEIQAKSHSLHITLQALFCVVFAISGQSLFGWNNDAIFGVLRAGRSFAAHGIESAICPLVSVIPTIVDLVPKLSSSNLLERSQSFVTESIQHEQVALGQIQRWLGVTELVDVLFSCRFDTGEQVSDVIEHIGTSRSSPEFIFAVEFVLQPIDDAIEVRVSFTEPEITPAGVLSLFARLEQVLENVLSRNNDIACDSIINQSSVDNVQDANIIDEPSTSVESEQILQKYISEFLGIELPALRPTTSFTSLGLSSIKAVSLSRVLLQHGINISPVDIIQGDQIREIAKRAHASACLDDAPETTEWLNDMKERLANELIVERLKLEPKDEIVITGCTSLQTGMLAQTINSRGILYVHAFTLQLAFDCDVSRLQAAWHEAVQNLTILRTSFHFTPISGQWAQVTHSIIDFKWSHSTQDELGSAAADFITTLAFDNEETFARPPVYFRHVSADMEYLVVVLHHALYDGLSLPKLFHHVQQLYQSKPVDVSTPFNQVADTILVAEGNGTAFWTRRLESVKPCHFMVQSRSSEEAWRASTTLDITTAEIQRFCRRYHVHPQALGQATWAKILCMREIRSDIIFGQVVSGRSLSGADNVIGPVFNTIPCRVSLIKGQSNQQLVRDIHRSNNDALPWQHASLRSIQRQLHLGSLFDTLFLFQPHVALTHENPLWHLITRQDMQEGKTQYAVNIELHEGEAFYSVFASCSSDAMTQTELASLLAQFNLLFVEIVRAPNAITLQDQAQIFSRPINVSMPPTSLKASGDPEAAIKIWSPTQQQLWKILIDFTGLPSDAIRPSTFLIAIGIDSICAIQVASLARRAGIPLAATDVARSPTVQDLLFLDPVTKKGVVTQSKPNPLELSPELVQNILARLPIGYQRKISRLLPLAAGMEWTLSAWQMNRAVFPFKLDRNNEAIDVVSSRLHNAWQKLIRRHEILRSVLIHTEEQNYRVLLGILSMEEFEVPWEEDRLPSHDLLSNKTELELVRMKTKELAVMPISFGQPPTQLVLLHGKQSSYIIIGLHHMQYDGWSLPLFMRDLESLYTSRQPLSKNDLSSFLTMFTRSSEYFLEQEVYWKHAFPHTFRPHLFPCLNRHRVLDETTHYDISFLSSLIRSVSSLRNLFSLGWARNRRRITEGEGGADAPLHVSRGRDRTFINITIPNDILPLDILQNKARSYSLSLQSILLACWAIVQMNWSSSLDGATFLLSHAGRSSAAIPNLDVLAAPCCNYAPVHVNLGIKRAGALKISAMTILDVARRIQADLANRTPVVEQTRVADISKWIGLKGKSFCNVAVNVLRLPGGQSSKDAETPERLLKAIKFPYSTVPLQMFPGDPVFPEIQVGCIIICNQRRYLTELLSLCSTTVLSKSISVQHPLRPLNRQTQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS62</accession>
    <name>A0ABQ8VS62_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="660" mass="73771" checksum="8E2D91E73B88B582" modified="2025-10-08" version="1">MLFSSLPAEIYAALIEQLDEPDVRTTLFALTRAIPRSPVPRYQLFRRVNITKADQLIALYQRIRPRKQDIEHQGEDPCKWVQGLYLETWTADAEIVLNLLTLLPNLEALTIWIGPKNFTPEHLEELFSVDRGGRSLRCVENLLYLSLRFRPYVQKATYHQFLSGSYFDSILEALSRWPPGRLSTLSIVQDPLSMESGTSEGSEVSPPPTFSLGLPQRTLASGFAQPIVFFQLESTFPGLLRAPYLHVPLQYLRLRFPSRNITRSLTQAPVPYLPSYGASIPAGSKPSKRYVRHVANAHLPPTPYLKFLDLSTCLISERSLPQILIQYPSLTHIILDDCNILRNGDIAVRDDSREWGSIAMSCAIAGIGKAKEKEKLVNAWLNMPGVRQKREQKLDDRGQYTQNKTRTRGRKGIANASLSIHKKDITSGSSITEPHVHDAPERIRILPPLPTLRHVTANLYVPPSMIPSETCALPPDVLDPLLVNIHREWERGWAEGLAQLIKVRERLHTSWRNNLVRVMRFATPEEISTLSNDFEKRLGSSGTEGSSLSRSHSPTNSETGFYEAGDENEIKALEDPLATLIEVTDRQEFDLDIGDNSSTSIGKAPVLCLAGSSLTSSMSYEQNASLLYGVNMGTVCIQGLDHASSCAHVAGRKLWLDGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSC7</accession>
    <name>A0ABQ8VSC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_815084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051640">
        <property type="entry name" value="GRB10-interact_GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445:SF36">
        <property type="entry name" value="FI03272P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445">
        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="325"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="758"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="809"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="909"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="918"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1142"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1151" mass="122575" checksum="AE02D0805EC0633B" modified="2025-10-08" version="1">MSTTTMHFGPEWMRTKPQPASRIQSPPSPPPPNASVHTASTYSSLLTTTAAAPAENKDEAHPFRYTKEEMLRIYREGGGKGGLGLEVERWDGVVRETVTDPIGLKEIGEAEKKLFATPLNSDLRRRQSTDYLHLNTQNLERPRLSHANTVSATGSPLRERFGSLMTRRRDSTDQPPTLPRRLSLTSQTTNANPRESGMPSPSPRGRLGHTPGFDGVLNGGESWVARRRASEGLLPKIPANSARDPGEESKELEIREEDEENHLDSNPEPDPQLGSKATNQLAMQKPDKIESGAALDVPATLSVSNSPASTSASVGLPPGIVDLSSVEWSYLDPQGQVQGPFQASVMQKWGDGGFFSDELLMKRTYIDNDWIPMGDLKRLVGNTDKVFLTPIPLYGPPGLIRRTDSPFSNLNSNPNEGGYHNGPLQPSPVRTLRNSTLDSFSSNYSDSPTSSFGAAGRFGDGSPDPAAFGGRAAPQYVLPGEMGPRFNGYPGEASPALSGRSGFAAPANDYRSPGFSNVTQGRANSLDVNPGFASPATSWPGFDGMANGRGGSIDSSTYHPGHPNAGMSSPFGNNGFQTSFGTQNHPSLGMGGLAFEQYPPSPSVQFTNTSVMPNAVPDIFDHNQLQQTPARPSQPSTNSSAAASPWGSGDSNINKRNVQFDTTSAKPPAVNNQSPWGTGRVSRSSSQANDLSPWLAASKGVTDNWKEEPSVISDLTSNNLGQHDREEKQLQETAQEVTEIITGPKATIAETQADPVLAPAVPLPTPSHTKTSRQAQQGTQVKAVTTEPAHVILDIPEPQSVVVPSAAPKAWAKEEDSKKSATSLRKIQDAEAKKVEARKTAEREKERAARVATQSIISPSPEDVQTFTASWGLPTSKAGKGSAAVTPKEFLLPTPASASAAPPVWSTTAAKPVATKKTMKEIQEEEERRKKTAAKETVANVASRRAYAESTSKPSPTSAPGASAWTTVGPSGKQTPVATTPTRPPATPTAAAAVSTTSITRVNGAATRPTPTPVSKAPVNSAKVDDFPIAPSTDFLKWLAESLKGLNNTVNVEDIMSMLLSFPIDPDPSTSEIISDLIYANTTTLDGRRFAADFLSRRKADAVARAKAGPGAATTKMVSIADVVKAQPKPQAQSEWGGFKVVNKKKKGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTA4</accession>
    <name>A0ABQ8VTA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689:SF1">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="269" mass="31555" checksum="10F0F86ACA165F5C" modified="2025-10-08" version="1">MMIVTHVQEARNVIHKGILETDTLHDAQDPDHRLVRGRRDVPPNTEISRDRKKRKGRADSVSSVSSSDSERRRRKKKKDEKRSKSKERERKERKERKREKKERKEKKKKAGAHASQWGKYGIISEVDIFSKTSEFQTWLVEERKINPETISKDQNKKEFARFIEDYNTATLPHEKYYNMEAYERRMSALRAGEYLPPADDHYDPSADMKALSNAHKKKGADSSTYLSKERLMELRKVQNERVEAGKMKLLGMDIKQNMGVRMDGTVFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU58</accession>
    <name>A0ABQ8VU58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_710115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="66" mass="7134" checksum="C7324CF06E14C463" modified="2025-10-08" version="1" fragment="single">CVDCILARQTTRPYDKPSNPNVDPLELVAIDLWGPSRVPTAAGNKYMMVISDSGSGTHGGEFLKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU59</accession>
    <name>A0ABQ8VU59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4498990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="30849" checksum="994A56B44507B5A9" modified="2025-10-08" version="1">MALRVTYNVTRMVFKFARLAAVNPEQTMSKRPLPWSGTDEHEYDEDYSPYTRVRLIMQNGRYEDELDLLRLKTTELQARVAELDHEIDEIINLDMEDVISLKQDVHLYYRQYRRARLDALELQEELAKTRTNGSNGTDEHKLSDELIALRAELTELERRINPDVKDVGSEGIEQVESEVSDRINTEGVTNENIEHKPSDEAILLQAELIELENQVNSDVTRVFDNNTLTSLPRFCVKEKGRNLMGTPTNQSNTQYASSLLSNLFNSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUP6</accession>
    <name>A0ABQ8VUP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">hydroxymethylbilane synthase</fullName>
            <ecNumber evidence="2">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_815277</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13645">
        <property type="entry name" value="PBP2_HuPBGD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="entry name" value="Porphobilinogen deaminase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557:SF0">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobilinogen deaminase N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobilinogen deaminase C-terminal" evidence="9">
        <location>
            <begin position="239"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="37104" checksum="C2DA0CB33EF11C35" modified="2025-10-08" version="1">MTNSSRTFVLASRGSQLAQIQTNLAMDSMKSLFASSNTDAIPKFTTSFMSTAGDKNQSQALYLLGGKALWTKELEVALIEREVDMLVHSFKDVPTVLPEGCIIAGIMEREDPVDSLVVKKDSPWKTLDDLPNGSIVGTSSVRRVAQLKRKYPELVFQDVRGNLNTRMAKLDAPDGPYAAIVLAKAGMVRLGMGDRLTSDLPPPLLYHAVSQGALAIEIRSNDEESLKICQQITHQETAWCCLAERACLRKLEGGCSVPVGIGSSLDGNVLTITGCVTALDGSKHVEHTITETVTNEEQAEAVGTKLATTLIEAGAKEILDDITIDREMRIKLAQEKDEKIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUS2</accession>
    <name>A0ABQ8VUS2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_811687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="31007" checksum="E35B5B10A796AAD3" modified="2025-10-08" version="1">MANYLPINAISAVIIISGEIGTPNETWKGPSIPVVLQRQSVPSLETGVLDDYATKIENRTFSDFCEPYPDPPFEIPAPANLSLQIRLGNVLSEGKTSTVFDCECFIPVGNETLGYNIPPMVVKLAKQYRSENLTKEAIMYEGMKCLQGSSIPRCYGFFQVRSLEFFDFGPMSLLLLEKLGGLLPLDKPIPDCTKSDIEGLCSDLAHLRIVHDDLQYQNILSTLSHEQGGLPSLPSPISGRTYGWKLAGFDGAYRTSTTLWNVQSFYNYHLPEVLEDIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUY3</accession>
    <name>A0ABQ8VUY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="567" mass="63374" checksum="21C9C927BF1905AB" modified="2025-10-08" version="1">MEPPAIPVEILNAIFDFLSDSTSDLKTCSLVSPAWHAAAAKILFSELHLLCSLDHPNPPALPQSKRRFDLAYGIFPVYRKKWLMEDTDAHCICSDNQDRTIQSFCSNGISSMVNITSNVARLKLMFCRSGDGPLEPVSNGPHSLQLYPDSTISTLLQLIDELSFVHLRFLTIDSAPQVLYFMICEPFSGVLSSAPSLEEIKFTSFESMQNSDIKRLLNKHTFSCTRFPRLRRIVFQGLFGTNTSGPYGPRMSCALELARTDSITLHNASASFVSVGVSYSSYQDSLTEPDGFSRFEIPGWCCFSGLCKNLPESKSLVDVMSLGSGFKDWSLPTIGIILGAFQSDTLGLFARTLDVKVSSDVNDPSGTKLFAYITQTYPRISSLNLFFSSIVEMRLALLHNTEQGSDHPLLERITIIQQLLLLSELSSLKLTLYDNAAFMTVLAFHIVHSQNQSLTVMSDLRPDTHIIQHQLEIISAMDSWFLDLALLSISRSRSLYGPLSSSLQEVVLVIDMHDTNSVWDLYHRTHSSDFDFQAASTLDPRFIERELEIMFPRVRAASPNFLTVQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVG2</accession>
    <name>A0ABQ8VVG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_811193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177:SF1">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="2">
        <location>
            <begin position="209"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="470" mass="53176" checksum="B3E4984907745A6F" modified="2025-10-08" version="1">MDSRYKTSTCMPIGASNPFPSCSSSPMSESEAEVASQLIASQPESEDNIPESSSQPRTNDNNNWTGRNQYQNRPKIGDESVHQALLEYHRRNITNKLTISELLKADYGIILSASSVTRHKKYWNITASQVTTAKMAELDKRQLVFDEMSKDPNAKRGPKTVKENIARVAGVHLTRDFIEATMRDQHPEGFANREPTAKKIHRSALVCVGPHQEWSGDGHDKLTGIGFPIWAVRDVWSGKWLGIWVVPNNRLKDTIAYLYLKLVYEYGGIPVQTTTDCGSELVMVYGFANALREAFAGDIPVEQVAAHRFLQSIHNITIERGWLRLRLEWGDNVKIFWDAGNTVYNAAIPEHYNLARWLWSKLIQSELDDLRDKFNNHRSRKDRGKWLPSGLSPNVAFSLHEKYGAVSGLLPVDREIIGRLMEDIGGEELVRFVSVAYAAKAQQVFNGELGAPQMTMQNVWHIFQDMLPHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWD7</accession>
    <name>A0ABQ8VWD7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Centrosomin N-terminal motif 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_874730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24622">
        <property type="entry name" value="TMP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="5">
        <location>
            <begin position="132"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="581"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="979"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="729"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="979"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1000"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1027"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1042" mass="118977" checksum="6AB220D1D5DB7C43" modified="2025-10-08" version="1">MSDALLNAFTDSSMQSLSNFELTLGSLPSDFSTPPRPGFRVPSATSQTTAQSSAAVTTPPPATISFRRKGESSLSRKLTAETDVEGNLETPSAEKSRWGDAGLDTPSSARPPASRHRSRPSISGSQKGVPLTLRDQEKHIDSLKKENFDIKLRVHFLEERLAELAPEQMDAALKQNITLKIETHNRGREIKRLKKLLLELERELERLQRSTGNRGARERELEAKLEERDREIRELRRRRASIDGGDAALREVEGRNTELEEELENVRGLLEDNVMEIERLQDLVERKGNTSSAGDAHRIDELESDLDQLKQTITEQAQLLDQKEDDKVDLLDEIEALRLNIENLQQRREVESIERSESRAQMLEEREEREAVEDDLNALKDRLAAALIELQQKEDDIERKDQVLEDMASQHQQIVGEVEEEWRGEVAEHKQQVEELRDVLAERDTECKELRITVTELEATMNDLHGKFEATLAHLEQEADDKDAQIESLNEAIEKLSEQVYILEDENDKFKEDHDKMKEEDDAERERLETLAAALKEKLTKLKAELDEMTEMYETCRQDIHAHHSRQEELATHVETLVDELEREREARERAESDLDAADKEHDAKLRAERRALEAKESALQSTLDDLARTQSLLTQREADLQAVQTALQTLETESKRAGETHSTAQFSLQLEVDRLKRDLERLEAELSRARADLNDKDHKGRDRDGAFDKLHAENRDLASQLAAQTQARLNISEKLDNAQASLRTAESDIASFKTRVSELEMRLSKDQRSLLSAESQYRDQLTERNTLLLTIYQYMDKILGVDKTPKKSGQAETKPFTNFGVFHDNLITRLKALSQIQMDFDKRCKDIEGRFTEKMADMRKQLDNRWKQIDKFEAGVKAFAETKTTWRRKYNAKEGEVEALKTTNAELSAQLSSTKRPGQTDSMEIRSLSARAVTAERRLNNAQNQLLATEEKVASMSQKTAAADSKWEARVKEYEARLKSAEERVKRERQGSKERVNELENQLKSLQRQLELAQKRSQQLTGVIDSNKAGSGSANSSPSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXY4</accession>
    <name>A0ABQ8VXY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_899546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="401" mass="43049" checksum="91912F2348AC99EC" modified="2025-10-08" version="1">MPAPAVYVIAVLGTVAVGFAFKEYVYDPHIKPKSRGYEMETLNPTQVRTRTRTLSREGIESWRTGIQSTISATTLRKRNTATTSTMPADSRSLISPSSSTLVDRSRQTRELTPLIPIQTGSELGNEMNTHILTDVDTETISDSTSPSTSSIRQLPSEASIISTFDFNAPETPAPSSTIMISTDHTGTSFEQLDNLARVSNPVGPATAVDPPSNPNNNPFLDPNSSPLTTPHASSPLNHSTYPTYPTYLTTQPDMWSSNPSITESSTSSPSMVPSLSLSYPIARADIEDGVVLLSPPSSDAYSSYSVPTSRAMSPAVSEAFTSLSGVSEVSRMSMPASASASVESLSDFSDFSVLESASDRSGPASRIASPLLSTGDADNEYYRWEAAFNEQIGRQFAKCRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY06</accession>
    <name>A0ABQ8VY06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_197461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="89" mass="9804" checksum="F235B763F1085F4C" modified="2025-10-08" version="1">MGTKAAIINSHSAAIPPAIHGMDISHYFPSLNIVPSRSTGPITSRITFQNPHFSAVFSQSFLSFVISLDPNNKINPREDITPPWPMYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYY9</accession>
    <name>A0ABQ8VYY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SPT2-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_806379</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691:SF8">
        <property type="entry name" value="PROTEIN SPT2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691">
        <property type="entry name" value="YEAST SPT2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="407"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="49554" checksum="7D982C1C5F102A78" modified="2025-10-08" version="1">MSSFASLMALSATYTQASQNQAQAKLAERNRREAELKKRRLEQEKKDREREAQLRLKHFEQQKKEEEQKKKKEEERKAIEAAVERRKAAEREALLHGPAKKTSSHRASQVRRKAPADNDDDNDGLKSEPLTREELRERKLQAELRRQFTSVKRSTTTGGYQRHGRHLPGGAVDVTTTGPPAPSSNGQSVKARLAAMPNTLTKLNTVKRDTRTIDEILQDRAKAKELKILDGHEALAFDDWFGTKKKEQTRPSSIGPASGENTPKSTASVARSTGTPPINSAKKSSAKPTPSSRPVPKPAASKPIPRYSEKSEKYSSSKLARPNASSSTSRPSTSITKKRARSSSRSESPRPKRRAISSEELDDVDNESLDVSGLIWGIMGKNRSHYVNMDVFSDDEDMEADASALEREEKRSARIAKEEELVALEEERRHEEDKRRRKMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ35</accession>
    <name>A0ABQ8VZ35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_357301</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045119">
        <property type="entry name" value="SUN1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911:SF8">
        <property type="entry name" value="KLAROID PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911">
        <property type="entry name" value="SAD1/UNC-84-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="7">
        <location>
            <begin position="875"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="563"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="659"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="747"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="979"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="563"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="757"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="979"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="998"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1155" mass="128279" checksum="0AEB83C21F8A9CFF" modified="2025-10-08" version="1">MSFAGTPLGQGRRLDHQTFLGKPPSSNGSTGNNNPQTQRITPVPTSYSSGAPPLGSRSPPKPSSSRERVDTTNLNPERWSVRDTSVNAASAIYQAMSNPNTAWASSSRTTRTSHPPRSTSVEYESQASNNVRRLGAPPSRLGSKANNKPLSMNSSSRSIVPDSEGEQSQSQILDYSREKSPFSFDQLTNLAQTAIQKTSYFVREKQREDQQPNGNASYDYSAEEREYQQYERNVNANASSSKNLSSSAVHRKNRISTDNRAYKPSQEELEESSDDDVSDTRRRRRKKGASGPAGGPLTTLPQVGPEKRRKKGSRKTKGGAANGEEEDEEEETDKEQNISASQRASVPPPARRSQSRQPDNSLSFIHNQSHSLNLDAIPEDPDPDLVDPESNPGEFYDDSYSHRSYLDDTHSLTSLRPSSGIGARLGTIVYTLFRLIGTGLTSVAHFAGRALGQIVSVLVLWPIRGVLKLPRNPLAYYFLVAFVILFGAWMVNKVPTGLSPLSSEWRLTSSWPFSSSGGSIKYSPSALPVENVAELNARLRALESTLSALVLENEQTKTRLRMTEEEVKEYEKERAKEAKEKEREQVTERQRERSRMQQQAIEREKERERATQQGKSEPGEIKEIVGRLGALEGLVKKDISGRVSKVEDVVGGFNRIQERNDKEERERQARLAVEAKEAREAREREERFKERLERDVREREQKERERDQREREKENQRQKEEKERQQREERERLVLNQVKKEMESLKSVIGALQSQPSSSGSGSSSVGSDIEARTQLALLEERIGSIEGGVKEALDLGNNALKTIKSSSQHPDPQSNWWSKISPSSSKSGLTIKSTDGQDVTSLLTHLVSSAVSSAVSIHSKDSIARADYALHSGGARVIPSLTSDTFALRAPSTFTSQLLGLIPFSGSGFGFGGPGSIAVGRPPVWALHPDITNGLCWPFPGSHGQLGIALATPVVVDSVTIDHVAAETAYEDGLVEVEEGSQDGDEDVENGHVEKKTNRRRSKRRSAPREMEVWGLVEGRENIHKVKEWREGLITQRQAKNAARERGEEQDFNHLDDLLGTSELDVPYPSTLPKSPTYIRLASFTYDIHSPSHIQTFPVLPYLSKYGKLGEAGVDFGVVVLVVRSNWGMEEYTCLYRVRVHGERGMIGGIEESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZF3</accession>
    <name>A0ABQ8VZF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_13154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="168"/>
            <end position="209"/>
        </location>
    </feature>
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            <begin position="256"/>
            <end position="295"/>
        </location>
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        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="616" mass="68031" checksum="089A2AE50BBD02FA" modified="2025-10-08" version="1">MQIELHLDPRIPFNIHLYLDKPFIVAYRTLIQTVYRFRDKFPRDGLRLHSRLQALYMTTTPPDEIIDVEATNSPDSSSLAQFSGIVSSSIISAPVDPTVSPSYHAHPPQLPSLLVPLPSAPSISSKDSISPALHYNIVPSMASFMHTANPDPINSSISVPPILAANPEPLLASTTPQPPAKPPASSLPERLQSDESISAVAKPRKKKRKKLNLSEMLDLDQADQVESPMGPISIVSTEGHGSKVEAMVLDPAVKFSEPDLPTPDMQGSSTVGIKRARSNSSSGMRDSHSPNSLDRVLKWESPIDRTEHEHHPLSIEPHESAAAHITPTLVEDKDKDSPDAEDAMEVDIEPAEDNGPEDEIMMDVINNLQTVEASLTTSDKVESVKAVEVLPPTPDSVNDAPSTTMALNDAPQFINIETKPHKVSLPEFSGFSKTLNTRKQEGLSTTAQITMRFTVDREQLTSLENWNRRNISPIREDRKETLCISLACYLRADMAKNPGNYNALKSRWPKRHRLDLNVTKQDGTNKTMPLNPPTVCTPDGFVDLGPFIEQGENTIKISQNGDLSAYVFCLHVHDPTLAQIQRLNQSLDANMEWELWCKSVSRPLNLEPSTFALHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZF4</accession>
    <name>A0ABQ8VZF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1224"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1357"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1364"/>
            <end position="1374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1545" mass="165983" checksum="3DB2FE820972FB5E" modified="2025-10-08" version="1">MTTFVTCSSSTTQHTSVHKIRRKPAPTLLSPITPITPLRALNVTPAGSLPKATSNSAKPSVTPASTSSPSNPSMKQALVIHTRTASTSTSLFIDHRYPPPDPSDPFAPLSVLRDRSRRCSTNAILSSSYTFAAGSDDTGHLKGKKVGMASTDNLSVASSTKSSFMPVKVAKKPGVIRTFPNDFIKEKKRSKHPQERISMCSVELHPDPLSSHVLDKKEDGVFGVPETPKKRSITPCPSHYESKVSTPTQFGTLGHYTPHSRQRTRSSFSALSSPSPTFKLSNRKQHVLIPAPDAHPLPSLVRDRSESSVSGSSSSGTGYPNYGGNTGEPTSTPERVLPPASASILSLGSPNASHLDISDSYALTMALLSSPQKHPYARSEAYTRSQSSSSSRDSSPCRSDYGKGVKSEQTPKAARMKKIDIGDTERPTSPTGSMFKLARFFTGGKVSRKNSIGSLKILDGITSPKSERRKANSPPSRGRARLRKLSLSSINISGPVAAPVSIPLGSDICHRVTGLPLIERSANRPRSQTTSGLPPSTIPNRLHSSPYRLETSSKSSASVSAIGITTVNEFDISRDQGVEDDVNKELNLSLLKPWTASIPRKRSSLSLSVLPASTSLEAGETCDAPSDIVSTLNLMDTSFGTCEPRKNNGSSESAVSAGSMGSSYIHVVDSCGESFVKNEPVHKREEDLTWTGARRAPLPPRSKTEGLLKSTANHGIAGIKFPGFRRAQSSVQDPIQGTTLLSTPGSVRGLKISSPMMQTTVSSNVKLDSPIALPSSASLASPLMHSPAKGLERAISESSCTFLNHSSPVNTKIAENDDAALSPPLPTTSELQALLALPLLDEHGQEAIFGDILNDPAPVNSDKAVIVLFIRHFWCPLDQDYVQEVGDILRRLSKDKDGWQLATSNGDLLIGDEEGNKAGKKAIPEVIIISNGSPALIAKYKEIFDLEAEKGSNPKVKMYTDPTCRTYGVLGLENVGEACISVVSTPSTPASKHSSTISSSPDSLTSRRGRGGITPHKYDTEIPLARTDYRTPLRKNIKGSFPPSASANIDSRSCPDSPSPSAMLSVLETSEPALARSVSPLSIESTHVSTSRSYVKHTSVIGGIATVVLRAIKVGMPVWEKGGAIKQLGGEFVFRVMKEQLYDQETGRDPEMQVACVFAHRMRDTADHTPFGDVLKIALTASPSNDFVSFCPSAACVTPSSITHPAYSLRRSSKAMYSPYECSTPPLRGSQTASSAPCSPYKPSRRKTQIDVYTTHTSTAGTAWWVAPTDEGEEVLSDGSPEDERVMHDSVLDTLKDGPVGTWGDKLHTLRTRVAQDGNRGVSDSIRGIRVRDSICSSTGTATDTSIRAIRAKRVPRGPRMRMQSVSAESLTASRSRDTVKSFGSGMEGIESVMEYGDSISSPDLSIFGQLAIAAGGPSENRWRRRRATDSTSTLNSSLYYDAHEGLLGITDNDDEELSKSLAVDVAPIVSRPASRLWREENVDSSEYQDQTFNSLQSYDTSADRTDQLTSLCSETSDDDYEENAEKLRELLVIRASGSIRGKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W153</accession>
    <name>A0ABQ8W153_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase III RPC4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_862270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="406" mass="43942" checksum="CA701885CB1EBB3E" modified="2025-10-08" version="1">MYIIFVEGVRKASIKNPYSLLGSGSKPKAISSLAKRPSEVTRQGTQKLKFVPTLPARRSKDAVKIEPVPDTIPASSNDRGRGRGRGRGEGSGRGRGGPRPPAEMVASGPFALGPAMAGTSSSRRFAQAATPIPAPSNTKASPLGAGLSQTAAPKIKREEQKLEKDEDEEIYSDADEGVEIIDMENVGQMDWMAPDSIIKEKTKRPKKEDPDATVQEVNIANALDGDEDEADEKDLETMFDDLNKMNYDTDNDSQYLCLFQFPSPFPTFSAQPSDTMQTDAPVTPGSKKVTFAPDVKLETEGLSSTAEVQELDGLIGHLEVYRSGARKIRLANGIVLDVSPASQPSFLEHAVHLDMKENKLTILGELFKHYLVAPDIDALLNAMDALDSGSQTVLAGEENLIRMDIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1V9</accession>
    <name>A0ABQ8W1V9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_808158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="25310" checksum="B1FAC92C8600F58F" modified="2025-10-08" version="1" fragment="single">DNDIISKPLLQRLGLGPGDDINRWSHNTNSWCTDITTCAIEIDKKRRPILLKKPEVTTPLNLERYIERHDNLKSDKKVLKRTWEEGLQEKQSIEEGVMKRICSPKPKTRQRALTAPTPSPTPSPPPYDRYQTEAHAADMRQYLKETLLYVKSPQPVTLESPQPVMLKSPQLVTPKFPQSATPKPDTRGEDGTMRAQLKEEHRVCVSGVVASGRPWLLEITLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A9R2</accession>
    <name>A0A9W9A9R2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8J55DRAFT_430281</name>
        <name evidence="2" type="ORF">C8R41DRAFT_861058</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000155">
        <property type="protein sequence ID" value="KAJ4463691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000018">
        <property type="protein sequence ID" value="KAJ4477801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A9R2"/>
    <dbReference type="OrthoDB" id="3205170at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4477801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="134" mass="14931" checksum="BE165FC81B10E158" modified="2023-11-08" version="1">MPSVLSKAASRKASQSRNPGNPLHPVSPEELESWSDGGDSESTLNETLPDDLDEPWPYTFHKGQAVWVRTSGGNWHSGRVSSETTRKGNTRKKEGLFYPVKFDGNLRKYFAPQNGEIKPDTPHIRGLLKKGGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9E1B4</accession>
    <name>A0A9W9E1B4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="5">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF6</name>
        <name evidence="6" type="ORF">C8J55DRAFT_497570</name>
        <name evidence="7" type="ORF">C8R41DRAFT_809369</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <text evidence="5">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000002">
        <property type="protein sequence ID" value="KAJ4494756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9E1B4"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="5">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="245" mass="26360" checksum="10B2DB81808CE34F" modified="2023-11-08" version="1">MATRIQFENSSDIGVFSKLTNSYCLAAIQGSTNFYSAFESELGDVIPIVHTSIGGTRIIGRLTAGNRHGLLVPSTTTDQELQHLRNSLPDAVAIQRVEERLSALGNVIACNDYVALVHPDVDRETEEIIADVLKVEVFRQTIADNVLVGSYCAITNQGGLVHPKTSIQDQDELSSLLQVPLVAGTVNRGSDVIGAGLVVNDWCAFTGLETTATEISVIEATFKLQGQDSTAVIGEMRDSLIDNWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWU3</accession>
    <name>A0ABQ8UWU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_860445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="57" mass="6537" checksum="50FE5479C18A978F" modified="2025-10-08" version="1">MRTLHFIYPVKEISMCCIHLGYKHTRYFFLVTSLFPVRGTWLGKSVSAAQLTIAVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX85</accession>
    <name>A0ABQ8UX85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_985404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000138">
        <property type="protein sequence ID" value="KAJ4464591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="3">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4464591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="489" mass="54286" checksum="03D9095D7D631A9A" modified="2025-10-08" version="1">MAQTVSSYEIVADVENFIHAGSLISYFLVSNIALFIYDLILIFPAELELVWSADIFGMFNVLYFLQRYMPFGSLILLLFFDGVVSPPMSFTSNSCMTLYIMSGLTFAIGICGSQVVLLWRVWTLWNYSAKMTFVFTGLFLCGSVFNLVIFISTRTAEGYPGPSVTSAVHCASQRYVQPLFFIFWVLLIVHHAGILLLMLIPQGYSLLRMQRWSDLINLINDIGIVYSIYLLALSSLNLAGALRLPANLQGLLIPFQHVMETILTSRAIIHWKRQSQKSQTTTALDLTGTSFAEVFEPSNESASIPPHPSSFRRSGSTNRYSLEEPLIFLEDPHDANFVNGSPSVDTPSQNNMDMGSLYSELIEDGNPRLFPPSPSRESEIIRRSLSILTPSLAPSEISDNSDGPSGGDQAREMGSSRDTMQTSSSYETLPSYHSRVSGPRRSSSRFFSYIPLNRSLPPLPRQFANGDGNGVSHQLSVSTTDTPPSYRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXL3</accession>
    <name>A0ABQ8UXL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_927295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000155">
        <property type="protein sequence ID" value="KAJ4463698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27310" checksum="84063415E19457D9" modified="2025-10-08" version="1">MKWATMIIPRVSHLSSLHLVELCLPPTFPAHLQSLSSLCQLVIRGCCLAANTSFDQCHYLITRLHIEGLCWHDHTSRSFELIRTCPEVEHLKLDWFCYLYDENPCLPVNLTSLVVLPPLLSSSECVSRSALSMLGHCLSSLSTISTFLVEGTSPPVVDVDYSKTLLPPSLTKFVGPSTFLSLAGPCHVGLREVALTDDDLSLSYIMSMLPLLPDTRSFRAHVNELASFLCERERKEFNGHSNQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY65</accession>
    <name>A0ABQ8UY65_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="7">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_781503</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>deamido-NAD(+) + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07570">
        <property type="entry name" value="GAT_Gln-NAD-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4465609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="719" mass="80715" checksum="10BD63E7B54E0141" modified="2025-10-08" version="1">MGHLITLATSLNQWALDFQGNMERILESIAIAKRRGATLRVGPELEIPGYGCLDHFLEGDTVLHSWEVLAKILASEETSGIVCDLGMPIEHKNTIYNCRVIIQNRKILLIRPKMWLANDGNYRELRYFTPWTKHRQVEDHFLPRIIQVVTGQTKVPFGDAVISTADTCIGVELCEELFTPASPHILMGLDGVEIFTNSSGSHHELRKLYTRVELIKEATLKLGGVYLYSNQQGCDGDRLYYDGCALIAVNGRIVAQGSQFSLNDVEVVTATIDIEDVRSHRAKSSRSMQAAQAEKYPRIEVPFALSLGKFEEVREEDMIGFLSTKTMEVRYHRPEEEIALGPACWLWDYLRRSRTQGYFIPLSGGIDSCATAVIVFSMCRLVAEAARRADKQVIADARRIAGEPEDSGYLPSDPREFAGRIFHTCYMGTENSSAETRNRAKNLAGAIGSYHIDLNMDTVVTAVRNLFGFITGVKPEFRAHGGSNAENLALQNIQARLRMVLAYLFAQLLPWVRGRVGGLLVLGSANVDESLRGYLTKYDCSSADINPIGGISKTDLKKFIAWAEGSFDLPILKSFLDATPTAELEPITENYVQADEADMGMTYDELSVFGRLRKVEKCGPYSTFTKLVHEWGGFLSPLQIAEKVKLFFFEHARNRHKMTTLTPSYHAESYSPDDNRFDLRPFLYPSRFPWQFKKIDEVAAALPDRSYLTTTNVGHKKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYQ6</accession>
    <name>A0ABQ8UYQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SPIN90/Ldb17 leucine-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_780820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000118">
        <property type="protein sequence ID" value="KAJ4466066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030125">
        <property type="entry name" value="SPIN90/Ldb17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018556">
        <property type="entry name" value="SPIN90/Ldb17_LRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357:SF1">
        <property type="entry name" value="NCK-INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357">
        <property type="entry name" value="SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09431">
        <property type="entry name" value="SPIN90_LRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPIN90/Ldb17 leucine-rich" evidence="1">
        <location>
            <begin position="218"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="49046" checksum="D21B09C4E9AA48DE" modified="2025-10-08" version="1" fragment="single">MEDDLGIVYLVDNAQQFWSELEDILVIPKEAIPTLEQLDLTLKRSLSLCAAYHEQYLQSPFQLEHACNMLLDTELFVFHSERMCDIVTSEAQSNTNPHFQFICFHVLLSFGRRRSDFFRSHKRWQPLLPVLMDHILVEIDSDVEDTYFGLSAGVGSGSGYSGANVPVPIEAKLRSLGVRLLYEMCRVQKLSIQDLRIFDDSFLDYLFDLVEQTRHMQDDTFNYSVIKLIVALNEQFMVASLGDEAGTNGNGANRHYQSSPENKNRVMRVLMRRLGSSQAFGENMIFMLNRAQRTPEDLCMQLLVLKLLYLIFTTKGTEEYFYTNDLCVLVDVFLRELADLDDDSDSLRHTYLRVLHPLLTKTQLRTIPYKRPQILYMLESLIRTSNVRDVNPITMRLVQRCLGGEWCVGLVRQKQVKEAKGVNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZP6</accession>
    <name>A0ABQ8UZP6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_898276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="25"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="360" mass="39519" checksum="B1B44F846610D2FD" modified="2025-10-08" version="1">MSERWILGPQETQFYTRTYTPLSGTPRALVVFVHGFQEHVGRYTHIHPSFAENGIILWAFDQRGFGRTALDNECRSKNSSWGKTGWSDQMQDVDWAVRTAREEFPGVPVFLMGHSMGGGEVLSFVTQQSYESPRHAETVASLTGVIVTSPLIKQTIPASKTLRWLGGKVATISPYTLIPAAVSPDDLSHSPEFNDAYSKDPLIKSTGSLRGIGEMLTEGEKLLSTGCHHWPKKIPVLLIHGDADKVTSAKATQTFFKVIDAEDKQIIIYPDGLHELQNEPPAIRQKFVTDIISFVQGRTSTPVPPRNSTHEHTGSNENNAGVTVASPESSSSAPNSTDPNAQLSLEIDQNGDDMKITPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V062</accession>
    <name>A0ABQ8V062_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_906903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000169">
        <property type="protein sequence ID" value="KAJ4463357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="39"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="308" mass="34980" checksum="626AE5C57AF8C3B9" modified="2025-10-08" version="1">MNITPELSAALPLRANWQPGARAKTADYTAKGEAILLHAMRDFEARIVGQDFFPDQTTRLRWAEKCFRDACATAKAQFISDKCVLKLIATRGSRIRGQVSKWIRANIISCYKFDVTVGKHAVKQNIALSRLLSSRNFSGFSYKDREAWTGYAEHPSIIFLLSYIFDESNMGMVFEKDFNPISLQTLASLFTMIRAAISEWSSGTCNKIKKFSEEEYDKYYKAYLIDLTKWDGMNPAVSLNIHHQMYAKSRIRMREESSDDSTVHIFGSIEAQLHQEMEARTGDTESKPEDSEIDDDNNEDDCGGSIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V080</accession>
    <name>A0ABQ8V080_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_860717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000150">
        <property type="protein sequence ID" value="KAJ4463924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF162">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="192" mass="21140" checksum="9A60496A488FA100" modified="2025-10-08" version="1">MQPAHETKHQSTLEYSFSPQLTLHLAQKSHSDDYSSIGTTGTTLWLGAQCLSAYIAQYHKPSRNTSNARAIELGSGIGLSVLVLSALGYSTVYATDTKLVISSVLARNIESNFHVAAKPGREILVRELDWHVSPENWNWDNDCAIASNTPQLSDGTNVLSSPFNLIITSDTVYEESIVEPFYALFTRSPYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3J9</accession>
    <name>A0ABQ8V3J9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_905388</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="282"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4472655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40657" checksum="30BCB3AEC8AB19B9" modified="2025-10-08" version="1">MSAPKIRPRGIHQNPRPGTTDFEFGQKQAAQQLIYYHTLCAALQKKFSVSVSKGFIRKSILTIPLSAGPDANGRLVGDPGITLGVLARRPLSDINFSEYTDFALESIRKFKLEIRPGGLAPQEDLEIWHNIFKNNFETREGNVLSCTHGSFAREFWPIIYNYHACGDTGDAGWNKLFNRLKSEGYPKSIIPCRYFGAHAGCWDGKCPFLHDKKSAVANREAVLKARRKTFDYKHKPTPQQSSARIRLLLNRRTGPSASFEEREALMTQIHKEVKGDRAYCANPECMNPWTKDQITSPLKNCSRCKFVLYCSSQCQKKDWPRHKAEPCAPIEVLVENDDLWSPIGTRKGTEFFKTNWGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3M2</accession>
    <name>A0ABQ8V3M2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="22854" checksum="361046922B3C99C9" modified="2025-10-08" version="1">MASLTGLQSPTFRMRLMCWAAMGATRVLRDSNPMQIILVEDDDSLYLPQELDSPGLREAYLSSGSCSFRTCTRSMRIPALYLIKLLKDTYDPNTELKDAQINHILHYDVEIPGVRHQNVKVTTGYSAIMKQRNIAVWGVSLAPHWPAHLVGAFSTTRESNMPIATPDNETAMPVQQTMERAHGEFYRLLAIPTGTEVYQFCAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V464</accession>
    <name>A0ABQ8V464_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Topoisomerase I damage affected protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_775714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21449">
        <property type="entry name" value="DLC-like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF7">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14805" checksum="D5FFBCD9BF24D093" modified="2025-10-08" version="1">MANTSGLRSPPTPRSEVSSPRPSFDSELLKAYMKKLLSTTLSSSLWPEPKDRDRVRRWMKEIGDRVKDRMLEIQPKGFKYVVLTQVNENLGQGGRADMVCHWEDTDTVAQEVYVNDSLICICIALAIRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4B0</accession>
    <name>A0ABQ8V4B0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48825" checksum="1C25E4F6FA80A5FB" modified="2025-10-08" version="1">MLLGNYIGNFTEYVPDDNEEYSRGEEPRYNSWYSPLGPTGLLQRSLSMVEMHRAVVTLLTTSGGSVDCSTKDRTLVTKDYGYFTDPDCSQISLDEPLTVTYGAGWLKQNSYFSFAKFIQIFRNNRRDDNQDIRPAPTHFALFLALSFSSILDHYCEPSSAFTIIGLPASLPQLKLITFTRIAHRLQAVDVCPWREDAYGKLVLMAGTPEETLSWFKHERDEPFCVLLSSSSNGLILVFCLQLANARCFWTFVWIPSTSMNEDELDFAQDIKNLHPDELFRDQPEVVPLLNNLPNLLLDVGTFGVLRVSGSCWAENYIENGIPQGLYPAEREKATWQIYDDAGTANPSIEEAHKTKSVKPSQEDDSASHISTRSRRLRATHVDSAVTGSSTRTGKNRKDTGRPLPSRRGQGRRVTVGVAPTDSTAPSSTPYNLRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V521</accession>
    <name>A0ABQ8V521_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="561"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="773"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1036"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1284"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1531"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="780"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1721" mass="191123" checksum="7B8F3AC4FF9DE091" modified="2025-10-08" version="1">MMNFEVRPIIGRKRQDLDPDVADDGSEVMQEKEYSPAKRFKEIPKSSPFVSRKSRRAHILPRTLRNPRQVRELRYLRASADLHGIYNERGPESVDEKSGLGAVLQARSNLNATNVECFDAVSQDLTSEPLAPHPGPLIRSNIDDETQLTPNFDLDSNGGVFSRVQSLNHASHEQSLVQSITSLSNCTSSTPNTFDQVQGVVGLEFMTVRGGPEPGSFSRPLIPASAYDQLEMSTSVGFDSNGDISTHPLSLNDPSYTGFPIAQNEGEDVDFHLDHDGGISTQPTPLFSPNDTSNAFHKAQGFPEFESFPGDPESGAQTELQMFPYNGFDSNVKVSLHARCLDDVSESGFEIAQNEGKEEVHSLHRDGGVTAPPRLSFSDYPPPHPHTISNTFDELGDNPGSDSSPYSHIPRSAYSHRPHTLSSTADEMQTLSIDGRYEDEDDGHRIEDPLDQNSGYTQFHAGNPVSDCSVYTHTPRSASSPHPHVLSSVEDETQTSHSDCRTEGEDDRHRFEGSLNRHSEYPQSHVGDPFDEFGDSPGSDSSPYAHLLRSASHHDYMLSSAENKTQTSDFGGRDEGKDESHSIEDSLNQDSGYAQSHAGGLFDELGDNPGSDDPRTIVFDEVCNKPVSASSLHPPVVISVEDKMQMPIVDGRNGGENDHRMEDSLNQNLGHTQFNAGALHVDSSNPTYFSDGVPIGHDITVDPPGFGSSSDVNVVFSHTSSNSAESSYIQPKFESSPHPHTIPDSFDEYGDFTFDSPYPRTTSDTFDEVSKDHRFESSHPRLSSNAKNETQMSNFDGRIEGDDGESMEDSLDRNSRYNPFHAGDWNELHIDSPNPTHFFDEVPISHDLNVTGYGTIASLLIINVDVSNHDTGSSSDVNTTSSNGAEFSYIQTGTPAAFDLDSQNAHHPDSSYMQSDFQRAYESFQIDSSSFPVPVAINAINTFELDEGMSNRYRLDHHESERNFAIQSNVIAASDHEVTIDLETGIRMSIVPWLDAYRAPYFQDQSPNAYYSDVRPTNEAVPDFVLQNHNRIFAPQTPKHPEAKGASSLLDAGAPNPSFGDSKTSYYVQTDARGSSNLPSQFPDANNDISCEGSKVNEQFRPMSNSQKPVDDFAGSLNHSIPGINSADTCSNEADRARIGSQSPSLNSNLALGNNYSSSFEMASASEYNMNGLSAFDDTGFDADDEGVKDGDGDWEMQCEDVRFDSNVGTAGNGNGSQISPDYESSRAFQTEVPPTPIYHNARADDHYLPCNTEHESCGDHHQGSQNLVDHNHLGVPSIQGNMLTPESNKTDRDIDNQQGVSPPSPLTEIPDTPIAADPSIEDEKYLRTELESLVSRCIKSASMKSHFISQLNQPPFDKIKLRSLLDSCYRYVGVLTDHDPPTPSPNIDTSHLFPRPGPKLYKAPQHRLHSRVELAERVCYEVGCLLGRVNDQHDPEFIAKPLSTVPSTTIDSWRRSGAGGPTLENFVLQLRGGKYTDWNKTAVQVFSRHLRSQEEYEGFTIKSIEEAFLAHLSQLRTDYDRQGRLKSIDEKDAEQRMRRLRRRNAELHRRISSLEEIFACHSDALRELRDVYKCITVECISGDESEPGQEPKLDRVYYRTTHAWSSQQFEEFQILLRAWHVGSRYIGSGKYSNGRFPHPRYPSSRPESIFDPDVAPRGLPRNWYDPGWLRRNPSRVEILAVGPDVPLTLPQEEVRFAKRFLHVKYRKTPPLPEDHPSLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5E8</accession>
    <name>A0ABQ8V5E8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="51963" checksum="1ABDE4A7114BF636" modified="2025-10-08" version="1">MFRITMQPLSFLVAFIFVPMLHQYSVLAFPLSLHSTHSRQLEEREEGTIQNIILVCREHPQSVIITDEGSATGTEVWTLFLGNTPGRNGYRTEFDEKSKDWVKSAKTPNRIRTHSKGGFILGSFKATRSANRKILERLDQVSAQMMIFYTYSLLLKLQEFGKNLESGVSDVDLDLGSQGIFMHRMHLLLSRGGSGAGLPVNNEDLQRYQQILTRLPFDYKKSPSERVRSSTGLQPGSSPLQLVQFFLIRKQNRHPFRCFKEGDIVGRDESWTFALTNTAGGLWGLRTTKKPDGTWIYVGEEKRNYVVPIKKGIAFYAIPLGSLKVTPGTVKTVLKRFRQVPADVNLLYLTNLYEAAEEMAKSPEFFEVQLDPTKFFPQMEQMLIKGGSAEGFAVTETERSRYKEVLKQHRSKDTPRIAPPRTPQLQTSGTPNYLSGPQLSPGNSTGYSAFDEFINMDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5I1</accession>
    <name>A0ABQ8V5I1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045912574" evidence="1">
        <location>
            <begin position="20"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="479" mass="54619" checksum="75DE7337A1879D1D" modified="2025-10-08" version="1">MLLILTQIFAFSSFRVTQSSLVCKIFDSSGFAELLPLAWTVAIIHPQHQGYVGEVTRMLGRAKFRRLVDNHRLGSIAKQLEVYFAKITSESIDHWIHRVTFDHNLSLINGPQMLLLLQILSEIPGNSVHIYLNKANGTMASLGHLIECLTNRRKIFVSGSDLLSSDQICIQCINAALGCYQIWLSGGARWVAAVLDHNLIFMAAKIRDFLEGVRDDDAGCENATCSTLVAICELFQHVRRYKPYFLVSHRVKLNLDLCEKRIVRKNLSVALVRLRESCPDIAFQDEWHMLRLEFYVKDAFALRRTSWDCARLLHCSFDQSQHHEHNLRCRQIASGLNEHPLYAEALGFVIASTKVSYMQSLLCAAMQKFENEIPPFTTELSDEDFNSEDLAVIIDLSQPGFGTCEIKLQRDIYDEVDNEGREVLSKGLAAVFCGLVPVFGSKHNLFLFKNREIHLEDGEIVGLEELFRVYALWWRNHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5J8</accession>
    <name>A0ABQ8V5J8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_65886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24431" checksum="274B202F8E8B15BC" modified="2025-10-08" version="1">MVTGEPQVIPIPGPVPTLRRGRSPGSTIWVEMEKRAHLFGALRNEPDAFTDAFISGLRKRPDLFQVVLHSETDPGQRFECFGSGNEALPAFQTRTFEALPPFINNHPLGVGEWQVQRSAADLLFGMKGMLGYLSSLTRPDSSGWFFQFKKIPVKCFVILNTVPHRHYSILAREVAWVVLCVLGFGEGEYSDSKYARASNRLFEKCAEVRFSWKPGVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5V9</accession>
    <name>A0ABQ8V5V9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_774768</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF305">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="205"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4474806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="400" mass="41536" checksum="4193E5935C003947" modified="2025-10-08" version="1">MPEGGYGWVVVASCSMIMFFAVGGFYSWGVIQAQLAAESIAPNSTLAFIGSLGVSFIAFGAIFMGRLIRWIGARNAGFLSCLLMGGGQILSSASSKNVGGLFVTNGIIVGLGTSMSFMLCSTLPSQYFRQKRGLANGAVYGAAGIGGAVLSVAQNALIRRVGVAWTFRIIGASVIALTFPACCFLKDRLRRSTATIEWSLFLDPRFVMLALGSAIGTFPLLVPPFFLPLYTNSLGEAASVGSVLLAVFNVSSALGRVSFGALCDVCGPITSLSLALILSALSLLAIWPVSSSLAPLIIFAILNGFGNGGFFSTIPSVVAHMYGPIRVTTVFSMVLTGWAAGYLLGAPVAGWLLDAYGGSGAGIVAYRPAMYYAGSLSVGSTGFILGVRVLTTKTNLFTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V628</accession>
    <name>A0ABQ8V628_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046064868" evidence="2">
        <location>
            <begin position="20"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="218" mass="23613" checksum="867C0E1A3C2A3C20" modified="2025-10-08" version="1">MRFLTTLLPLITLAVHVAATNSEQGSIPLTILRPGAVHLPDPPPPYNPPTYDEATRSHAIIPPPHYSSAQSGVEQPPLSGISPRCQQEARQRALELARQELGPNHGDVSNLRAVMERVTTSVGDAFMRHPGRVIACFLVTATVASATVAIYLSNCGKGDWACINKRDGFGSNPQCKHLDIEVCRNPSPTDTHSPSKATGGHGKRDAARMSYRRRLELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6E9</accession>
    <name>A0ABQ8V6E9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_983362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="338" mass="37318" checksum="3B1943B85EA0291E" modified="2025-10-08" version="1">MSASNETVDVGKIVIGFTEPTSIMEMFVLPLYGVYTALFGLYMYLQIHQQGRRRCYQFSLSLLYILASTAVVISILIGNQMTLFILDAIFTKDIDSPLTAFHFNSYANLVVAAEGIYVAANFIADALLVYRCYAMWSSRTYVISGLIIISLVNTTVAIFATVLTKDNIGNLLTTKGGSVSIQVADTIISYAFLSVNLFTNLLLTGLIAGRIWWMGRAIQRSLTTANHETDLNTMVAIILESGLLYPIALIICLVLSVYEGTVETFSLLTLIVGIAATLIIVRTDLKISIENAYCPGVTESLADEEEIPYDLVAIHTKPQPYMLHKENHFKPVKMGQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6V8</accession>
    <name>A0ABQ8V6V8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="33055" checksum="309A54A692E65CEF" modified="2025-10-08" version="1">MADVWSGDISQVISSLPQLESLCIFTNISSDVRGPLLPPPEVGGQQSFLPNLRKLRLRMSNPSKFLRWMLDHSMYAPQIHTLDIIIYNDTRNGWGLVYALEPFLIANNDTLKSLSLGLEYNYKLQHGMNDQRIQTLNIGSLPNLHSLTLQTHDIEALCQTMNTFLGSSPLVLKTLTLNLLPFFSLEESRDTNRIQSELRKCLDPKKFPTRTLLALNILLPLSGHVPSNQAFMLLAQHFANDILPNWEETGRLNIGIPLKTQFQVDSLETICGTIWNYKNVPFSRTLTRIGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Y3</accession>
    <name>A0ABQ8V6Y3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="143" mass="14495" checksum="DA2E45EC110460FF" modified="2025-10-08" version="1">MAGGTSPPPTQQRSRRRASRSLSVATDPGSRPPRNRRRGGGGQQNQGGGGGGPLGGLPGVSKVADTATGAVGSVGDAVGGLLGGVAGGGGGGDKPLKLRLDLNLDVAVEIKARVHGDLTISLLYVFFALMVMRLPSELNFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Z3</accession>
    <name>A0ABQ8V6Z3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_845023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="72"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="3">
        <location>
            <begin position="345"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="555"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="588"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="654"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="691"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="721"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="787"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4477612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="849" mass="93980" checksum="578FE0C711A17D34" modified="2025-10-08" version="1">MSKRTNTNSASPVQMFAQATQLAFHNSSFNAAGRDINYYTVFNDDEKMIHKWLGAPDSSINLCTALDKKTSGTGNWIFHDPQYIHWMKQGGMLWIQGKAGSGKTILLSTLIESLQTDPQKLVAYHYFDTRDTTGAKSSYQGLLASILQQLGSSNSRIHPALKVLHQSSKTGLMYAKPSNKSMENAIKTIINDLQSEGPVCVVLDALDECNENNSLQKFCTNLVSDMRNLWLAVTSRHLPDIHWGARILISLDIENTSGDIDVYLATKIAEDFQDFKSEPFKVEVKKALKTKAEGVFRWIDCQLNILKECKTSKAARRAMQNLPLDLQGTYEQAVQKCKNGPNSTEAYHILLWLLYAFEPLDQKQITAILSIDLEEQVVESSDEIAFKIENIVDSTLVAINSDGVVQLAHASVKEFLLLKQVAIQMNASFDMDAHLAHDTLAQMCIVYLLQWKDGEVLEQDFPFESYAIQHWAGHATLSLQGDQLGNVLRDLSHEILKASSFQYHHWTENYKLQTFLYDTKKGMNPFWWAACLGLLPAINDITLLDKDLLNQPTGDLGTPLSAAAYFERENSVHFLLHIGANVNAQGGKLGNALQAAACCGNVNMVKCLFESGANVNAQGGLFGNALEAASWNDHRDVVEYLLKNGADANDQGGEYGNALVAAAYEGNEIIVKLLVAHGADVNIQVEFFLGNALQTAAYEGYESIVQYLLLNGADINAEGGEYGSALKAAASKGHENIFIYLLDNGANFDAHSRQYEHVLQSAIRRGNERIVKRFLDDGADVNTQGGYHGNALQTAVFWGHETMVKQFLENGAEVNVSDGPYGNILRSVEYAYNGRNEKMIQILVEFGAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7H1</accession>
    <name>A0ABQ8V7H1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_772992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="187" mass="21428" checksum="3D90C1E80E570C36" modified="2025-10-08" version="1" fragment="single">MKRHVKYLLSLNDRRFQEHPSFIFTAFNILQCREMLLHISLKSNRSMFAKVANKFASVSASAVNVVAQRYAKGDTVSFNTVEERTVLELMREVNLVTSHVPWSPSSLVSMRNQIRGLMMDEGLPSFYLTINPADVYNPLVKFLAGSEIDIDNMLPDQIPRYWDQAVLIAKNPCVVSNFFNIYMNAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7U9</accession>
    <name>A0ABQ8V7U9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sphingolipid C(9)-methyltransferase</fullName>
            <ecNumber evidence="14">2.1.1.317</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_886735</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.317" evidence="14"/>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052290">
        <property type="entry name" value="Sphingo_C9-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197:SF1">
        <property type="entry name" value="SPHINGOLIPID C9-METHYLTRANSFERASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197">
        <property type="entry name" value="SYNTHASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4478934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="485" mass="55692" checksum="A66B3860791B9135" modified="2025-10-08" version="1">MSESKVKVTSYPAIANAPLVGLAEGNDTFSNLHLAGLVLFVPWLLKRLLPLVNRGGFKTYLFLLLLTGLPTTLAYWMVMSRIGSRKNEKVRLPGKNIEEYITIKDPELKKLYNGKEKIPMQVFHDAFFDGKIEFNGDILEIMEQRHDWAKFTMTWSLLKYVLTVLIPDVITHSREQDADQVTEHYDRGNDFYSWFLGPRMIYTSGVVLNPDEKETLEQLQDNKLAIVCSKLNLKPEDRLLDIGCGWGTLTAYAAKNFDCDATGVTLAKNQTEFGNNRIKENGISSEKARILCCDFREIAEKKPSGTYTKIVSLEMAEHVGIRRYQTFLRQVYNLLDDDGIFVFQVAGLRQCWQYEDLNWGLFMNKYVFPGADASCSLGWVVSQLQNANFEVKSIDVLGVHYSATLHRWYENWLSNHDEIVAKYGDRWYRLWAFFLAWSVITSRQGSASVFQITLHKNLNAYHRIEGVKSHASIHVKLEKEPELIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Z2</accession>
    <name>A0ABQ8V7Z2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear protein 96-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear pore complex protein NUP96 C-terminal" evidence="2">
        <location>
            <begin position="479"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4474226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="867" mass="96058" checksum="6E22DA3C18E43643" modified="2025-10-08" version="1">MARFRAFSDGESSSASSSDSDSENQIVKRARHVSYKDQKLPIAEEEEEDGAEEGEDDDEEEEEEDEDDEGEEEEEEEEEEEEEETDSELSSEMQEDELQLSKDRNLAPRAQVAGVDSQRMHVMQTSLFRMPEEAAALKAMNQIADSSFRKLTPTLRKHGRESDGDIRSWDTRPSFSKDVQPTLTRPTRKYTRVDSTMSVAVGAEDALADAGLSFGRSFRVGWGPGGVLVRPSSGTTVLKSKIPIPASDSLSPKLLQHQLSHSPISPDDGGVPFANPSPEVLLFSSFSSLFPATDVSQEASMFRLGSALFDPLSLHLSSQAATPEIRQRVSLLTRKAALSTWLQYAVAPAVQEYLQTHLAASAPAIAFAHLTGNQLERACDVATDSGYPTLATLIAQAGGDSQYRNDLLEQLEIWTNQKVDTLIDSDLRKIYALLAGDFTVDIVHGLDWKRIFGLYLWFAEPMHTPIAQVFNSFRESTDDGSEDLLFSLLRLYSDETCSLSDILQPRTSAGQLNYTIPWHLYIILSRCMRVRDFTDRSDVRHDSHVSIDVDQPEPEPEFEGHSPTADLLTSSYALQLEQQGMIQEAIFVLLHLEGSAGRRKAIQDLLIRSAPMLDEWNIRGLVGSLKIPLRWVKEAQAIYALNSFSPPPGHIVSSDHDSSSSHPAYVAYELFLAAGNLNRAHDIAVLSLAPDAVIRNDYDLLKELFSPFVPFSGDSDHGRVEGWYVRGKAFLDYASIMTRIPTLIPSETNPVVEGLEPDAVPDAMRAKELDDLVRGIPRLISLLPDVLTLARSGSKDGSRANRTDAAQLKLKHQVALHEMTARLVKVVDRVRPNAMEHVQPQLLDEATKLLHIRAAATSSFIKSIEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V837</accession>
    <name>A0ABQ8V837_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_922904</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMEM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045014">
        <property type="entry name" value="TM41A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220:SF18">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 41B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="8">
        <location>
            <begin position="143"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="357"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="357"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4478606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="418" mass="45429" checksum="4C301C824B2BE3F3" modified="2025-10-08" version="1">MTPSPLNLNRTANASVYTLATVDERHDEENSPHAPLLTPLTPSYGSTMPRSPGTSRSSRKLILNATLKMAAIFVVSTAILGITLWLALPTLEEKDRPMLRIPKSFEQLQDLNGLLKKYRDIYPYRIVICYITVYLFLQAFSLPGSMYLSILGGAVWGVARALPLACCCVASGATLCYLISSALGPALLTIPRIKKHLESTAARVQRNKENLISFLIVLRIAPLPPHWVVNVVAPHVGISIPTFWISTALGIFGVSVIHTTIGGGLDEMTSADDFHLISWKNFLGLSAIVLGVMIPVGLRYWFKRGGVTADIEEQDEDAPIPAMTPTPRSAANGAVFLYDEEEEEEDQILAAGATRLANNSKDADSRTQLLASEDDIDEDDYTSDDDDGDIILEAGPSLNDSESKSSKLGNPQSTTSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8L1</accession>
    <name>A0ABQ8V8L1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="17842" checksum="5E7AE3DCB8A90AA4" modified="2025-10-08" version="1">MDSPTDKSRKRGQCNQGSSNRGNRCQHTAPSATSNENSMAIPETESHINPTATAEVCGIGPILAHTQRPLSPSKNPALNSRIFRAMAKKTGQGSGQVASDVWYNVCPYSKLISGIGKWHAWKNTNGQSDGIRDHLQKEHWDLYCETVLKEKLKGFEKISTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Q6</accession>
    <name>A0ABQ8V9Q6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_773718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="427" mass="47035" checksum="B4457312C534F429" modified="2025-10-08" version="1">MDGLSGTWSPPHYDVSRPPGLDKVVALTSDPNFPQNFARITKWSPDGSVYLSQCENRSFQLGALYIGSPVTLEFCQSAPIVDFAWYPAATSSDPATFCFLASVRECPVKLLDASDGRLRASYPIIDHRERFIAPHSLAFNLTAQKLYCGFEDAIEVFDVATPGEGTRLATTPNKSSKDGLKGIISALAFCPSYESDMFAAGSLSANRANIALFSESQGEAPLMFLDGGVQAGVMQLQFNPVQPHLLYASFRRDTRIFCWDIRYNSDQPLKIYAPTSYVPFSGVNTQIDYPSFKESTNQKHRFDIDISGKYLSVGRQDGNILMYDLNNPLSLEVSEPQGDEIEPTIISPTLVFEAHDDSVGSVAFHPITARLLSSSGSRNFDDSGSSDSEDSVSDSDDSLKGTATSVSMRRRKRQPSVRDNSLKLWRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAB0</accession>
    <name>A0ABQ8VAB0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-alpha-acetyltransferase 40</fullName>
            <ecNumber evidence="4">2.3.1.257</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_840329</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-seryl-[histone H2A] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12742"/>
            <dbReference type="Rhea" id="RHEA-COMP:12744"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50596"/>
            <dbReference type="Rhea" id="RHEA-COMP:12740"/>
            <dbReference type="Rhea" id="RHEA-COMP:12743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. NAA40 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.257" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039949">
        <property type="entry name" value="NAA40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="12">
        <location>
            <begin position="57"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4484057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="210" mass="23851" checksum="44AAA771AD1ECE2C" modified="2025-10-08" version="1">MAEDEEKSLSEGSETVIRANKKSAKQLRLALKYVDGLPPAYECTFWLAKELSASMGAKIWELINGNMSELYVNSSLGWNALDKQQELFNPLARYIILNPVDQPDQIAGYSVLRFEHEAEEDILYCYELQISPLHQRKGLGKFLMILLQVIGRRTKMEKIMLTVLDNNSAANDFYATIGFQLDECSPSFEDPENEGDTEEVDYQILSKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAK6</accession>
    <name>A0ABQ8VAK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_839856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="111" mass="11900" checksum="9B9AD91CFB97F42E" modified="2025-10-08" version="1">MGSGDPELDNAPVAPMLNAKTDGLISRVFSLEYRICAAKPFLPVKSFPAHFLNTVAGYQYLLEDLPQNIGVSGISSTPGHLAVAFPLYLLQAQQGLTRIISAEGKSWISPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB01</accession>
    <name>A0ABQ8VB01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Quinate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_771847</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF34">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="24"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4479466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="538" mass="59253" checksum="983CA8C8DDD7F95C" modified="2025-10-08" version="1">MVKLFKVEDRPTPPEVYNWRVYMNAMIATFAAIMIGYDSAFIGTSVSLASFKNEFSLATKSTAEFNLISANIVSVYQAGSFFGAILGYPIGYFIGRKWGLFVSAGIFVVGAILQTVANSSIGLGIIYAGRIIAGLAIGVASNLAPIYVAEIAPPAIRGRCIGLYELMWQVGGVVGFWINYGVSLHIPTGHKQWVIAFAVQLIPGGLLLIGSLFLTESPRWLVSRDRNNSAMKSLCNIRHLPPTHPYIVEEMTSIEATIQHERNLAGAGFLGPLRAVFASKALILRLILGSSMFVWQNATGINAINYYSPTIFKSIGVTGQNNSLLTTGVYGIIKLVGALVWLLYIVDQFGRRPALIGGSAGGAVCMYYIAAYIAIAKPAEHPTTSLTPGGKIAFFYLWTVFYSPTWNGTPWVYTAEIFPQHVRVFSQACMAASNWLYAFLIARFTPQMFTAMGYGVYLFFASLMIMSIPFVYFYVPETKQIPLERMDEIFTPGLPVWCAHRTVINSIQHEQHAYNPQGFRSSKTSVTEKEEIERVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB44</accession>
    <name>A0ABQ8VB44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF260">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="35234" checksum="93677EC4989C46ED" modified="2025-10-08" version="1">MGMLEFISSQNIAGAVDLVAGGHVTTFVTDDEFLRAKEDYDAVKAAGIDISNVEWLSKEDMLSIYGVSFPGVRYGGHNLWPLKLVTHLYNFAKSKLSLSLHTSTPVNIVERNSETTNSHRWKLHTPRGLISCSYVVHATNAYASHLIPHLRGSVGIVPTRGQVVAVRGTSLDKLSLERPLYILGGGREVESRFAHGEIDDSKSNEEVAQVLREFLPGLFPGKFERGMEPEMEWTGIMGFTRSRDPFVGPVGGYDASNKHSNFDGQFVAAGYSGHGMPRAFACAEVIASMLFAEFHGKIWSAPKWLPHHFLTSSWADQPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBP3</accession>
    <name>A0ABQ8VBP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_869041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF14">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="3">
        <location>
            <begin position="362"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4480749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1244" mass="137688" checksum="B39EC545F1B8F8D5" modified="2025-10-08" version="1">MGKNTKAPYNNDNHMGDTEDLIGSDDSEWFEELTQNLVQSPVPTPRKPKMKKTRPESDPTITTKKIPTAIDLHTQWGPSSPFKISDHTSTRFPINAPRAPTVPNLTWISDEEDAGDTATDSSSSSIFDQYSGLSRQNTTSSISSFTPESSTKPNSVRPSDTGSLSLRAHAVPQPIIFDNPNSAISPSDDDSLARSPTLFSHSASFPSALSPPPTPSDSLSGSFPAILPKNIRKPFIIAHDKETQKLFDNPDGLVPWGAQYELARGVILREWTWEDVREKIHNFTGKSDADMMHSVCYIMKDVALPKLLKTDIGQESDREQLAVLENRERGLGLMGHFQGADHWFGGQIQQIATLRKTARCTLRLQLEPLEMRRSTRLARQFGSRRVLQVRIPEDLLRGEARRETIQYLSNKFILNGRVFAPTPPKEGAVYFIEINEDYERTPVDKFGDQYRKSLREVLDWHNPMTLNSQQPLSKYAARAALALSNSVPALLFEAENIHFIDDIIASDCTERKPPAHKVLTDGCGFMNEAALKSIATALNYSSRPTAVQGRIAGSKGLWTISPDQVANASDIPQIWIRDSQRKIVYPHFNSFSRHYVMLDRVHRTFDLCHAALPSLSTVGPMVSLKKQSVLNLWANGVPIEIFRELMEKGLQDMIQPLIQWEGQFAMPALWDAINKAGKVSHVRTTRLGAGMARALGLAGREYKKEGSTQGEADASIFSSTVSGRNEISGAPATLHEVAIELVQAGFHPAKDALLWSTLESVLRVTVQGAIDKCNIPLPEGSAATAFVIPVAHDQDADPLGILNENEIYYRSSTPMRDPNTQTLFHVITGEMLSLGIKLALRYPLRVTSDTQKVIAVDKPELAPWSDVFIVPIQPSQSGQGLVSMMSKCSGGDQDGDDLCGIWLDRLVKPFKVSPLVLEPRDISANFEDKVEKVDDFLNRIKTVPDVEVESSLISVFLQGLTDSNVGLYDEFHDKAVRHDGYESMEAVRLAFLFNHLLDAPKTGAVLRAAVSTEDRSQNQKYKKSLEHRAQTGSQESFIFDELEAFGLELLEATMAEFMQLPASSSEKSDVLLEPYRMAQRLCKVGCIPIDTATKIAETVGTSELGAKNVTQILLEARRLDLDLIEKHVDRAFHKFCSIAGTTKDFDDKKKKKKGKSSQSDVMAPAIALFAQEIRGLTNTLPNIDQVKASYAYSKGKTVNFGKTVAFRTLCEIQVAASSEGGAPCFRLLDQVKSISGGARRLFQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC19</accession>
    <name>A0ABQ8VC19_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_884672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045792573" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="16"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4486897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="58408" checksum="538D3FACAE7D3DFB" modified="2025-10-08" version="1">MRSLVFLSVGATAAGFSFTGVPSSASTNQASSATLIRDSSDPTAFSLLLRLTSQNGGSTIQEFSSEQETNIPFSFTPTESGVFIIEVISNLSPISDTQEPDKIYASSSSINVAADNQASLPSSTSTSSSENAGTSSSSLISNAVTSSLTASTSQTTTSSNNNGNTLSTAPSTSTLVTSNGDTSVAATAIQSDTASLTTTNHLSSSTEGSDGKGALASDSSESSTVVSVTESSTIVSISGTAGITNDSPTSTATLAPTAATSNSLKTGIIVGIILGILAFVGLCLALLVAYTRSRRRKRTDAFKRQLMTRQISPLVFNRMTSSPSSTEIDGSGDGDGYREYIPEEDYSRNVIETGTVQIAEQESSSLSHLNSMYSEQSVHSVYSDSPSVFYTAVPIPRAVGATTSAPSQTSPPPAPQTLSHSALHLTFDSDLKFPASISDTPSVPVASDSQFSTSTSQPASTSTLPQLAPGWVFPRIQPRLSQLPLPKTDRQMDIYDRKVRLQGKLIGLQGWGNVTASESQKAEMKEVSEQIRRLETLENSDWALGRSNEVPIWGLGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC23</accession>
    <name>A0ABQ8VC23_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc-ribbon 15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139:SF1">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13862" checksum="0C59B43164870285" modified="2025-10-08" version="1">MFFFLPLIFGCPTKVKPDGNEQTAHLCPKCNNASVFSAKSRTWFELFFIPLIPMNTKHIWMCGICRWVAPMGPGQWEPPIAYQNPQQNFGHMQGHIPSNGFQQGYQPSYDQSPNNYPPNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC28</accession>
    <name>A0ABQ8VC28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_910820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the RIX1 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the IPI1/TEX10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024679">
        <property type="entry name" value="Ipi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057949">
        <property type="entry name" value="TPR_TEX10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056">
        <property type="entry name" value="REGULATOR OF MICROTUBULE DYNAMICS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056:SF2">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12333">
        <property type="entry name" value="Ipi1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25781">
        <property type="entry name" value="TPR_TEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Pre-rRNA-processing protein Ipi1 N-terminal" evidence="7">
        <location>
            <begin position="139"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="TEX10-like TPR repeats" evidence="8">
        <location>
            <begin position="596"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4484045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="731" mass="80864" checksum="C5BE616EDFE0ECD5" modified="2025-10-08" version="1">MPKSAKRRKEKAADFAKAKLKLGKGKQAPSNAIDTSFKARSIALPSQSIAVEKDDSAPTTRRKLSLNDLIVNIKHHNPGTRKDTIFGFRELLDAHWELIDSSLPILINVTVRIIGDEDASVRKALLSFYSWLIPRIPKEDLVPHAPLILLFTSSAQTHIFPEIRIDAIRFLNIFLEYFPEVIVRGWDTANNSTGSRVLEGYLGVLSAGTITGDAEGPPVATSTASVILTPASKLVVLQSLSRFLEAATGIQSTSLTSEDFWFLSRSFHTKEAYITFNRLLRPSSTLQSSPHKAWSSEMEPEADIFPVASAMATHTGNLSCQLRELSDHVVLCRNFCESGASTSTGNPFVVRLAKTLHPTLVSVFLDCAPAVFSPSNGPPETEMDSISAVVSITRTLYSLIIQDSSPASAAIEELQIMLGYMAPFFPFHSNGRKDVKIEQTFQDLNFTYCDLTSRLVPASRPSAAASHPTTSRGKKARHFGNDASQANRVQEYVLEILQEQVSTSQLVRGLTSTAYNSLLPTIWSLLNYSGRNEEQLERSGEVLEAVVEHAVKIGSKSVLKRSTFDFVARLVLLETDVRYQGAFRLKTRTKADKLIEEWLTQLPQILWELGSSNPSVSEAIVLFLLRLLQRRSKILHDNTLASLQTRFAPYFHITHPTRGEILGPFNKLPKNGLSSPSGLRRRVLDVVILLCADGSSGEALRSAVDGALVNTEEYEYWAHLKHHFGRSQTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC55</accession>
    <name>A0ABQ8VC55_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_922153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4481801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="31477" checksum="4021386A454D5CEE" modified="2025-10-08" version="1">MNILFNRTPSSKRWIGVVITGLAWTLFASKGYASPLPAIPEQPELGTAVSNTNSSGSDYDYHYTNHTDSQTRPRHLQLDSRGVGLKKGLIRAALWLNPDWAVLGFAYVKPEEGEVHGDGSSVQLGALKLPTMKLDATEISFRRMYLLPKLGMPAQNPGVVDQDFSSNFVVNTWPYSVPGVCLKEEHEKSQGSNGRNANSINPHPLTHIFRSYSDHISTQAITFFSDPSFAGTTVMQVPLSAKIVDDWKLLAECYKTANGLPTKANPSWNMWKKEIEGLPEGMNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCA2</accession>
    <name>A0ABQ8VCA2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_896784</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF26">
        <property type="entry name" value="FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="2015"/>
            <end position="2161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1337"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1365"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1414"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1443"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1468"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1482"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1517"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1536"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1558"/>
            <end position="1574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4481846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2161" mass="242234" checksum="626A578DC7C786F1" modified="2025-10-08" version="1">MAKEVKAKPKQKTLDRFFKGPIASKGTKPSEDDDADDSMVIDEEEDAPQAKKGDFSGLPPLNDISAMFSDIVSRASELKEVATRLQGRKFRVATMCSGTESPLLALDMIVESISAQYGVKLDVEHVFSCEIEPFKQAYIERNFHPPLLFRDVCELGSDKAHTAYGALATVPGNVDLLVAGTSCVDYSNLNNEKQDIDANGESGRTFRGMMGWVTRHRPPIVILENVCSAPWDRVKEKFEKHNYSALHIRVDTKQYYIPHTRTRVYLVAVDQKNSPIPKKWKEWVERLRRPASSTLDSFLLPIDDPRIHHSRQKQAQESQNSLDRRSGRTDWSRCESRHQRARLEEALGLKRPLTSWDEGGFCKMLSFAWTDWAVGQVERVWDLLDISLLRDAKKGIDPSYKTQVWNLSQNVDRTIGSNKVGICPCLTPSMIPYITNRGGPMIGLEALSMQGLPVDRMLLTRETEDQLADLAGNAMSTTVVGACIIGSMIVGLRLFKKGNEKAVYGGGDAFEEFEDVEMKDIESSAKPSPELPVDERIVGEKSLIFEPLNLTATQSQSLAHLLGIASKTVRLCSCEGRTDITSRPISRCIDCGASSCKRCGGRPEHNTEPIDIIANPRLPPSTFEMELKSALPMCLSLLNVTAELLDELNEKTLGDLNGKLWKEWCTAVLVASSSDLRYVELKRQEVWSAIFRSPHGSLELHLDPQQPEWRFFAKPKDNEPANAQIRQILDNPVGRLICQGSLLSGQWAFALPKSTEVEITMKGSGSLVPAWESRLGLQGEAFREKKVWSEIQVSVPKADKPKFDRDISGTYELLDRCGTACNALHKQKGSDLSLPQLYMLLVPHRTKDFEDCFMFSTEIRRLEFGESRPFVARLSTKWRQSSTDDSEKVACLLPFQWVESSAINLLPTPGQDARFGIPQDTIRVSGSNVACQHAQALLSLSAPLRGQTGAEWPLGSWREVNKSDEREIFRSVAWLLERIKDVSGRFHSWQKVEGLDHSNCERCAPTPPDIEYMQVKNKIVGIEDPVQAGAYERRLKRRPSPFVTQLMLTDDGSGTVRIGINVPSLLHRALSRLPSEDRSEKPILSWRLDTNFTPAASLNLPKFTILSNKLDKEHAQPPSFKLNLRKEQTRSLEWMIRQETLNAEPFVEEEISEAVLDPLGWRAEGLAQRPVHVRGGVLADQVGYGKTAITLGLIDCTWKTVEAEFAKQKPIDGKLSLKGTLVIVPPHLTRQWDSEVRKFTGKRFKTLVLSTVSNLNSATIDDFKDADIIIVASNIFKSNVYLDNLSSLAAVGPLPSKDGRQFNDHLRTVCTALRSQTNRLREEGSAAVKAEIAEAQRRAEDEAMQVSQLQSKRLKGKSYRNAADALEKGKTTKEQEVSSTKGEPKRTRTVLDSVEIPVYRAKSELPSKSSDADISSDADHDEDENVSTKRTQRAAARKPIVLSDDDSSDDDPEIAPKKKATSNSAKNSRARKPVKRRHAMSDDGDDSFVEDSSNEGGSDEADSSEVPSEDDIPSPKSKPKKIQVKKKAAPPPSSASEDDMDVDEDLQSSAKKGKRKAKGDGNRPAKKQRVDTDPWKLASSKVLRDWTQMHAPPLEMFHFARVVVDEYTYLDGKVHALVNNLTAARHWVLSGTPPVHDFGALKTISAFLDVHLGIDDDGEGQSAEIKKRKKERTDVEKFHSFREVHTLEWHAHRHEVGQRFLDRFVRQNIAEIDEIPWSEQTVDVILPAAERAIYLELEHYLRALEMTVKRGRKTESDREKRVAQSLGESKSAEEALLKRCSHFEVESNNENAMKACDVIVQERQKQLNDCKENLLSAIKDGVKREKDLNKKLNNAGGESMFLEWLRICRTDGVEDLEATNIIRSLIDKADAPTMKAKPRKDDVTLSESVKAQVWDHREKTHEIRRLTKELVGRVRSLRYFTVVRDLQKQRDQPPVLSCPVCGREALEVEDASVLSSCGHIGCNDCVRSCAEKEECVYSASGGCKSAARVINVVKAETLGVDDVERDGTGKHFGMKLEQVISLIKKQIPKDDRILVFVQFPDLMKKVTEAFGHHKIQFLEIRGTAAQKSKNLEKFQNESKERVLLLNVMDESASGANLTSANHAIFLSPLLAPSQEIYNACETQAIGRLVRFGQTKHVHIYRFLTKNTIDEEIYLQRKGPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCV5</accession>
    <name>A0ABQ8VCV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Caspase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_836398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4488637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="55368" checksum="04D6FB2CFDE6AC5F" modified="2025-10-08" version="1">MPRPSRHIHLSEKPAELVVGQSNAKKALLIGINNTLMDQDGGGRRSRLTMPHRDVNSMRTLLIEHYHYNPNDIVTLIDVDDPKQLQPTRANIRTELRKLVADARRGDRFFFHYSGHVVQTENQDHTEEDGKDECLVPCDSDGVQNLIKDDELHGILVDQLPQGSQLVAILDSCHSGSLLDLEHYRCNQVWVPWMSTGRRKSDPIRNKVQRHNALIVYQHKRISGDRVKQRKTTILNHPLSPLSPERRRRVSREMPATPISPVTSPASPSTHKKLARALTKLDINATKGIHAIRRSSTWKNSPTTGQQVMKRSKTIKSQFVPWLDIERAEAAAAEGDTDQEGLQCESPVQQFCNGWCHHNSSPTSPKSPRSPGSPEIISLASCKDSQEAWEDSEGNSMTQRLVEILKQDPHPTMGDLMVTISHKLHDAAMKAHTQTKQYKDKIVRYRKKHPEKCKYPDEGDTDGLNLNDFQDPQLSSRKPLDMGRRFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD24</accession>
    <name>A0ABQ8VD24_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclear transport factor 2 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_920717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16442" checksum="9F1D9CA60E7DB7C6" modified="2025-10-08" version="1">MSATQTIHLYDRSVFSNEERAVLQVAENFLDGIGARNKTLMTEQVLPSGGAVLMRNGAPIITTLTGVIDRIPFDSPNKIEERISGQPIVKIDTNIAMLWTPYDFLINDKVDHIGTDIWSFAKLDGKWVVSSVADNALAPKTSASYNSTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD49</accession>
    <name>A0ABQ8VD49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_396756</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="3"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="553" mass="61040" checksum="5129280B002B212B" modified="2025-10-08" version="1">MSVNVLIVGAGPSGLSLALLLLRNGLSVRIVEKQLQFHPGERGAGIQPRTLELYKLLGILPDIIERSSPPPTNLRSFAMPDDGKPPNLTPIAQSLVNTPDRPLINARMLGQNRQEQLLRERILADYGIQVELGAELKSFEQQPDHVVAHVVKIVDSKIVEESFTVDWLVGADGARGVVRKQLGLTFLGESPEMDAVTGDIHVLGDSLDHLDFSIWRQSDQAEPVIVSMRPCAVQGKNLYQFLIGGGKRKLDIDKISSSRQEMVKAFHELTGRRDIEFGQLVWMGLWRPNIRMVDRFGEGRVFLVGAHVHSPTGGQGMNSSVQDSFNLAWKLTLAQKKFAPQSLLDSYSQERLPVIAAMLNKTTELFQKEFVGKAGQKQEFVRGYELRQLGINYRGAPLVSDEKFTDKDEVNDPYRSGDDGTARAGDRAPDAPCLAQLGVDETSSTVSLFDLLNTTQHSALVFPGSTGRYFADEVIGTLREYPSNLLKSIFILPRASDSASSFTLVDTEGHAYSGYHVAHDTPTVFIVRPDGYIGALVTSGRLGIRNYFSRIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD65</accession>
    <name>A0ABQ8VD65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isoprenoid synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="262"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="37239" checksum="B196982E33118968" modified="2025-10-08" version="1">MAPFPSQLVNTANISSYFSSFPVRSCELDALPTIQQALNDTIYSCTAPGSKERKKAEYRHTNPAGNLFGLSFALCEADRLGYVGKLIEFLCIVDDVMEDLPFGEACIEHAILRQALYESYDDDQYGGRAVGKMKSYLRELRVELANLNDPCTPLLLKTLDTSLRDRDSDDSEFQTLAEYIPYRKTNFDYDFVCQLVRWAMNISPEVQENLLVQSYEHAVGVIVGLTNDYFSWEMERQQPTDRIRNAVPVLMKEHSVSEVQAKSMLKEIIIREERRARELKSEIMNQTEESDQMKRYVTEMELFAAGYSFWCATCPRYHRLQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE05</accession>
    <name>A0ABQ8VE05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_867682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="239" mass="26716" checksum="CA61B9EB4F0FB654" modified="2025-10-08" version="1">MYIYGIREVVVDTKRSENAEIYMLCTCQIGQFITFSTPALSELTPVLRLVFAPDDDDVWIGTSEPSTDILQTILDKAVETKSSRPKERLIQKPPFNSASFPLWSKKNASKSLLVSVKRGNMIQAFANAQAQTNGFDNGVLSAIAQDKDNSYAICIWYDQLLRKVIEVLQLDEGVPAIVVLYCRGTRDTPANDTIPWVQEVSSKSASKTVPRLQIVANLEEQKLLLAVLNMNARRLSDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEM6</accession>
    <name>A0ABQ8VEM6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tubulin binding cofactor C-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_838056</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031925">
        <property type="entry name" value="TBCC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16752">
        <property type="entry name" value="TBCC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="6">
        <location>
            <begin position="119"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="316" mass="34887" checksum="981F975BE2F59CD7" modified="2025-10-08" version="1">MAEPQLVDGSRWNFSQTFLNNFQSLRSDLQTRIEQANQSVSISQQALDGLNLQLAELSKSIVDATGSIPKFDQRNCENQLKEIEQSLEGLRKSSAPASKFAFKRKAREAVQSSSNVSTPSIKASAASTSSLTLSSYTMKLVTPDDLPDPETVAPELRSELSIHDLDSCILNLINAKQEISALHIRNVKNSILLLPTLDGSVILHDLINCIVVVKCHQFRMHSSRSTDVYLSIQSNPIIEHCHSIQFGPYPATFSPTIVQHNPDVSVQDFSHIKSTPSPNWTVLDEGARKSPEDWQSISALDATDVERILQKALPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEN3</accession>
    <name>A0ABQ8VEN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Magnesium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_841463</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane magnesium transporter (TC 1.A.67) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018937">
        <property type="entry name" value="MMgT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10270">
        <property type="entry name" value="MMgT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046851739" evidence="7">
        <location>
            <begin position="21"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4481814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="99" mass="10933" checksum="CDFDEBB10D0E76C0" modified="2025-10-08" version="1">MLGRFFLLFATLLILHAAFSTYEHLSHLKSLGKPEGSLPYDIVLEAIIALALGILGASLNASSLKETTWSSQMKTRSIDEMDARLGFANYVNRGRNIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF67</accession>
    <name>A0ABQ8VF67_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN" evidence="2">
        <location>
            <begin position="103"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="391" mass="42831" checksum="B8338E29216E1D20" modified="2025-10-08" version="1">MSRALGAAFLNHQVEQLEKSVGNVHGPSSGNWRDRTSKYNSGNPNNSKHNASKRVSSKVVNANNRKRDGEFQLLTRDRESPKSEQGLKKRSNEQQEKDADIVIVDASVLVHALNHLKKWCKSGREEVVIVPLEALNTLDLLKKGTTSLAQRAREASRILEAQVGNNPRIRVQRDEAFVPWDAIDFQLESDNTDDKSNIQNSPEWVRRTICCARWEVQHASPADDIATKPNVVIAVCTAITTSPSNATTKLPDADANSTALLTPVPLPAPSHAHFNKHEPRTMGSQVSRWAAKAGVTILDLKPAPPPSQSTPKSNGSTGYSGHPRSSSEEDRPKRILTNKGGRRPPSAETGKLKGGLVERSPAVSIMMEMVQRSDSKAVRVLARGEKLDPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFF1</accession>
    <name>A0ABQ8VFF1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="23625" checksum="8D3C6BEB6DBB8033" modified="2025-10-08" version="1">MSYESQIHQSYRAHNSCPRPLTRTYPTDPLALSESLPSSSLAANRVNFPLTNLSPRSLYIPFSLFTRRRLSTRFQTVCRPPQPQLERLLNPSRSASLQHASPASHASPAPRSDVSACSTLALNTTISQPSFFTVTQTSALTLPYPSGYPCVDLWKNCKAAMKCERCGGSQKRMARDISTPTSIVIYGKWNLASAYPGREQAESGDIGASLARNGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFH2</accession>
    <name>A0ABQ8VFH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_343023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16014">
        <property type="entry name" value="PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF1">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045594599" evidence="2">
        <location>
            <begin position="20"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="655" mass="71389" checksum="9F8A0A7FA183C63E" modified="2025-10-08" version="1">MISLLNTLIVTSWVSSAFADSLAEVEHIVLFMQENRAFDHYFGTMAGVRGFKDPNVQVDPDGRSVFFQSVNSFLSNDTDFLLPWYLAAEGGQFINGTQCMTAGSNGWAENHAALASGQNDLWVEANMPQSWGHFRRSDLPVHFAIAEGWTVGDMYQQGVIASTNPNRVIWQTGSIAVPGGNVNTTQGPVLDNNETPGCSSLTQRLENGTEIDSPKNYTCYPFDWKTLPEYLEDAGISWKEFQAFDNFGDNPLPDFVFWQNLADNNATSELAQRGLAMNGGGNWQGGLDLLKKQAAEGTLPAVSFYIGPAELSEHPPYRPIDGAWLQKEVVNAIVNSPKYNKTILIISFDETGGWGDHVIPFTSPENTPGEWIINPFTGQPAPTGPGFRLPFTVISPWTRGGIVFTEPSDHISQTLLLEQWAAARGTPFINTQINDWRREHMSNLTNMFDFENPDYSAAPLPDTPPPHTDPLTSLLDGDVFCENTFSGHVQPPIPYGQQTPTDSLFTETGFKIVRGSLTEGRYLVIESSTKNLALSSNDSSLGTSAATNDKINTPSQRFVIHATDPKIATGKSFRISSAASITDATAISNATTPFLDVNLQFGSANSSAVFNITYQGAGVYNFLESGSSKFLSLGDNGAPVLGSEAESFKIFSISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG06</accession>
    <name>A0ABQ8VG06_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pinin/SDK/MemA protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_919654</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039853">
        <property type="entry name" value="Pinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707:SF0">
        <property type="entry name" value="PININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707">
        <property type="entry name" value="PINN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="10">
        <location>
            <begin position="45"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="234"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="61"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4493190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="35148" checksum="88F577A18E160936" modified="2025-10-08" version="1">MSEEAATAPAPTPTPDAAEAAPPSVPPPSRPRIALGNGTRGGRGGKSMFGLVLGTLNKAKIESREREASDAAKRRQLLEARLQAKLRNETAEVRRQEEAKKDKTLAVRKEEELGVRVSVYRLRRTRTPYLANFLCTSDVILDEQTMEEDVEQSDAQSFAKILEKAKPPRSHPPPLYYLPKKLLPSQEAFLKKRKEEARPFRIITVASAAEWSAFAAERDASVQEIRQLREKVSNAQAIEREEKRERNTNAEGDGVDATGMDVDGSNKDGDKDAKQSTESTSAPTAADVTSEEKDKTAAMDVDKPSSTQPENDNDDAVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGI3</accession>
    <name>A0ABQ8VGI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_867693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="243" mass="27146" checksum="DDB4332F819F4DF9" modified="2025-10-08" version="1">MVEAGEGQESEDLSLDLESKVSNRSPLSFPQLMPPGVERLTRKSIKRPATITIGEGDLVVDTVDLFGKRERKCVERTGFHATWYDVEHSHCDQRVIRFGILEDVDEPVLENIDGPGKMRQAPLYASARYAQNATSDRTAEAVINLQGSAETRIVVRHLRDVYEPPSSGSEGAFGFSIPKKQTHSFLAKNNCEALPPEKSLGTQHESQLLAFEIMQDCWVSFAALVKRHNHLACKVYSTRYLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGJ7</accession>
    <name>A0ABQ8VGJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_333403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="68"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="56965" checksum="0D3E48E874982584" modified="2025-10-08" version="1">MILAIGCYVDLNRPAESPDSEKYHMLARAALCEIPVLEDTTVETVTALYYELWFLLVFSDKKKSTDQAWALMGLTAKLAQSIGLHRNGVKSKVIPEEVENRRSLFWELLCLDSRLALSLGRPPSLSVKHMDCSRPMYIPDPHCDFLESSHHYQSWKHSFYVDCLYPIVDAISQPGIEYSTVLELDMQVRNFPIPEHLQRQNSQSRIMLLQQVSFTMAYESVLLQLHRTYFMRALSGPEEAFNKRHRYAPSVVAVWLGAVRMIAAVETLYRREPELAARILGYWSNTFSAVVAIALLVSRAPFTCLSPAGLQELQRARLLYQAVTHTRSSEIVPMLDIIIAKANNIFQRWYHGQDVPTLVLRHEDEHDTFIDQLIKMDSNPFVPAPSPPPTDDSFQHAHPLLTQCIAEAHERAKIMFPMRKPCQCSVGNPTTCPPSHSWTPPPHIDLSRPILPYLYAEIANPFGFDAAPAVPPITSHYTGSNSVNFELGALHPNTEQSWMGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGL7</accession>
    <name>A0ABQ8VGL7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_765489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="12616" checksum="CEA084725E6360F2" modified="2025-10-08" version="1" fragment="single">IIRALRLRVAHLPVKFVVAGTLIPEKHFRSNVGEWDDFHWCSDTGFFENQDQHRHYVSQFLPPEFAKSIAGQALLKRMWQWLRGRHRYTAAFISILLANNFENTHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHA7</accession>
    <name>A0ABQ8VHA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_763922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="747"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="804"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="833"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="959" mass="104286" checksum="C990AC9D40E4460A" modified="2025-10-08" version="1">MHTVVSLPQSTRAPRKSSSYATLRRDKQQTNTDPPSSYYSSRPTYLDSYPTSQRSTNFKSTATTSKFSSTSFDFHSFPSTEDFDSSSTVPNPFPRERSRTGPSSQNPNWIDRSISPRISVTSTLTEGTSPDTPVDNASFRDFDVLVAAPVSGVEMMDALVDGMNGGEEIGLSSRSRFGIPNHHPLYQPPLPTPPPGVVLGGGKSRRQKKPPKLVHRSSFSDQDDDQDNGPPTATPKRRRPFLPGRSTSNTTITLASPSSRSPQSSAPPTPIDTESSLYTARPRTAPSTPSSADKRRSLAPSISDIIRAHAPQEAQARARASPLNRAPSYSRSVGHTTVREESEPEPEPITAEEEADLLSRSSIDSIADEVRRTLRHQVSMKHVAHPPPPPHRHSYISDSASIISPRSDGCGTASLYSSSIASSQPPLSPFDTGFMSKPTTPSQAVAQYLRSTRLTTLLKLTRSPHASHDNPLTVSLSDLGSQNGFPVLVFLGLGCVRHVMGLYDEMAQCLGLRLITIDRWGLGRTEPRAKSAKGIIQWASVVEEVLDRLHIDECSVMAHSAGAPYALSFANKLPHRIRGEICLLAPWVGESAGYKWLKYVPNGILKTAQAAEWKLQTWMIGKPPTLAWEGIGYTQQAGKSSSTSSPGSSSVYSESYPRPSLASSSFSAYDDLRDFDGRFESMSTLGTAHPNITQCGNNRNESKMQVTRKSSRGILGRLKSTPQSPSVNDQSPPSTGKRLKALRSMGSLKSKTSPSSSKKQQSLPSPQLPISLKVDVSLGLDDTTWPKSFNCDSSSVSTPEKFPRSGSRRSLSLSSSSRPFNTQSLPPSPNPPSSHDLPSSSSASELPSSPNNAFQAAVGNALIAASHSESAKGTHNDLLQILNHDHHPWGFSYEAYPHKVQVWYGDRDEKIAENAVRWMEKTMGEGMCSVRVVKGADHGLMYKSGVVVDVLEYLLSFWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHE4</accession>
    <name>A0ABQ8VHE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_764690</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="145"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="87"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4493178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="589" mass="64840" checksum="61BC30D7C214A940" modified="2025-10-08" version="1">MHITTPNSQSPDSKNGLLQSVTVPTEEVLPSSNRTYTGLLHDLKRILHRTNRASTTPQQPLSRLLSLDLLKKKVKLSSIFPKEKVNERDLSPFPSSGSASNSELNRSRSPLPPSTLKFRSHHSQNSSHLTRPININHANLHKKYGKWGRVLGSGAGGTVRLIKGSQKTGGAVFAVKQFRPKRKDESEKEYQTKVTAEFCVGSALSHTNIIEVVDIITENGQYYEIMEYAPYDLFSVVMSGKMSRPEIYCDFRQICEGVEYLHSLGLAHRDLKLDNCVITTDNIVKLIDFGTAIVFHYPGTKTYIKAKGIVGSDPYLAPEIMTDEEYDPRKSDVWSVAVIFLCLILRRFPWKCPDMGTDASFRAFVDAQKDLSMSKSTESKGVILSSQLELELSTTAKVDVEMDPSVIRLGRPGNSTESLPEFTTFPISKSSPTTTISGDVAETLKESIGLQEVTLKRSNSVATLHSGEAGSIFSLLPRETRPALRRMLHVDPNARCTLSNLLKGWGKAVSGFDLNSDMSTLTGTVNGVGSIDEHSDSASTLTFNTVPCVNHDCNAEEEDGGDPWLTSIATCSTPGVKPNHVHVKVTRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHG3</accession>
    <name>A0ABQ8VHG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_829894</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="72"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="507" mass="55232" checksum="6C208E81999A4BDE" modified="2025-10-08" version="1">MSRLWHWSRRCSRIFTRPNSSLASQLNSVTDADVLHFSKILSSPSSVLSILPSISTSPEELDIYNNDWMGKYFGKSTTVLKPKTTEEVSQIVKWCNDKRIGIVPQGGNTGLVGGSVPLRDEVILSLSNMTQVRSFDPISGILVTDAGCILQSLTDYVAPHNHIMPLDLGAKGSCQIGGNVSTNAGGLRLLRYGSLHGSVLGLEVVLPDGSILDQLTTLRKDNTGYDLKQLFIGAEGTLGIITGVSILTPPAPQASNNVILALPRFENVLPLYKTVKRQLSEILSAFEFIDRTAYDLAVKHGQGRALSEEEVEGAECFVLVETSGGRREHDEEKLNDLLESLLEAEEPLINTGVLAQNPAQFSSLWALREGVTEAVSKEGKAYKYDISVPLSTFKECVDLTRERLRSKGLLNGDQVKAVIGYGHVGDGNLHLNVIAKAYTPEIQDALEPFVFELVASHRGSVSAEHGIGAMKTHALHYSKDETSIAWMKKIKAIFDPNGIMNPGKVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHS7</accession>
    <name>A0ABQ8VHS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_715669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26630" checksum="82EEE2109D84B781" modified="2025-10-08" version="1" fragment="single">LVDAHDRIIAVLGGVPPGSKGKEWEAVEAEAAAAAMCCRESSTFTEAQKHGRRGEFASRTVGYGYGNGRRKPQNYKVSGRANQRAVQELLQNTAIRRISGFQNALFNTFCHKNYVEHRDTNEEVQRKQPELRANFLHSAFAATTFNLGPLSFSPPHMDPENRASSWCADTNMGPFDPDKGGHLVLWDLGLIIRFPPGSTILFPSALITHSTIPIQAHERRYAIIQYSSGGLFRWRDNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI92</accession>
    <name>A0ABQ8VI92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_918801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="16"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="237" mass="26921" checksum="17BFEB11C33A154F" modified="2025-10-08" version="1">MTDSIGDLESLYRLKYLSGVALSVMVYDHLLTLNEEFSNIWAAPNRDYFQKLMFVINRYYTEAMVMYVVYVCSGLANLDDAYSPNRADYYTETAVFITLRVYHSWDKRKQVAIILLVAFIIFMAAAAALAVLSAVNVQPAIHFVSFLKACEVPDIPITFPFMMGTLLGFDLFIILVAFFNAFERPHKTHADVLDTLHRDGARSFVVSVVKPLTRNIYAQVLVNTAKSRLSFYFDSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VID9</accession>
    <name>A0ABQ8VID9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_827838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36658" checksum="E899687A83DEEA51" modified="2025-10-08" version="1">MSPTFDPKKDLVELKGKVIIVTGANRQSGLGYSTVKHLVREGAKVYIAARNEQQSLESIEKLKEDLRLGPGSDGQVHFLKLDLGDPRNVKKVAEDFMAKESRLDVLVNNAAMVMAPFEKTSDGISKVVVTNLISPFVFTQTLLPLLTKTAQEEDSDVRIINVSSITHYIVPSIKKLETVEDLNQEFHGRPVAKFFRYAHTKLLIIIWARALHKHLNSLSSITPGASRITVMSLNPGNVDTFSNRWPLPWLWRPLVRILMTAPNVDVGVYPMVFAAAGKTIHEDREKYTGAYISEKRDVVDPSSNARSDKLAEELWILLQKIMKDMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIH5</accession>
    <name>A0ABQ8VIH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_827998</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08066">
        <property type="entry name" value="MPN_AMSH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044098">
        <property type="entry name" value="STAMBP/STALP-like_MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015063">
        <property type="entry name" value="USP8_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947">
        <property type="entry name" value="AMSH-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947:SF13">
        <property type="entry name" value="FI19924P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08969">
        <property type="entry name" value="USP8_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="10">
        <location>
            <begin position="447"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="120"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="199"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="304"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="394"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4495441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="619" mass="69218" checksum="396C7F0080232CF1" modified="2025-10-08" version="1">MASNQHPQHDRRRPAMISELAARASSNDWNENGAFKYFLRLAERYRKEAKEAVARNDLEEAFVAFARSATIVLEILPVHRDYLTSLSNAQRNNLTLNGQELLENLGHLKPILLDRFDNWQAQHPDRGDTPPPTLAQSQQERQVEHDRIVAEEARRSQQEADLVRRGQAEQPRHSPPPDHATNSAVPFAQPVQGIASMELSQRHQRQQEEMQSRSQELMRRKQEEKLRTHASSPSIPSTAGTSSNSSMIMPTPSIAANSSAPSLSSPATMYHAASKQSAVSFQPPPVSHPNMYRSISQQAPTMLPLENPSWFEDDSTDSEHDSRTAAQRYATPTKSTRSSYPAPLTTMSPPPPDRIEYPKLMNVHQKTQGYRPSQDSMFTQTWNRDHYSLSDAYSQPQRENYHPLPRPPSQPPYTGPNQSAPAPPIPTETKPSLTPSGAPETSNGLKIVHLPRDCLNRFLTIAKVNTARDRETCGLLLGKDRGSKFVVTTLLIPKQHSTSDTCTMDEEELILQVTEERGLITLGWIHTHPSQSCFMSSVDLHTHSAFQRMLPESFAVVCAPSSVPNFGIFRLTDPPGLGLILACNAKEAFHPHPDAPIYTDAERGHVQMKDISLEIVDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VII3</accession>
    <name>A0ABQ8VII3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="45847" checksum="AE286FEC2D247896" modified="2025-10-08" version="1" fragment="single">MSPTPTRPSSRTPSPLLPPLTTLGEVPSPAPESDGEVEADELAFTIESPSRPQLQLFETVFNTGKSLSAYCQDDPLWPVLAEVASPCTNCLKTPEKCKVLPSSPRCTNCSSKKTCSLGKILRYRYFTRRCNQDLAYSRRFLELHGTPAHKSTWGIPLTVWREYDSALHARTSSTSILLELNMLDEQDAVDADQQELQQFLTLQRDEAVVAAKRKRNRSPVPVAGPSSKKIRSDASKKRSRRKSPAVEVNVEPFRRVRLVVPPVRSVAPTSLPVPPPASPSLMGVLRRDLPMQGPSDLVRLADAAEVHPGLVQQAGSSSPARTPIKGTGQDLLSSTMPPILRPALVPRNPASHPYRAENQRLAARVHLLETQLADSQRENSSLTSALRDTSHALESRQREVEQLRSSSQEFLQRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIL4</accession>
    <name>A0ABQ8VIL4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HbrB-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_828682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013745">
        <property type="entry name" value="Bit61/PRR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32428">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32428:SF2">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08539">
        <property type="entry name" value="HbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="510" mass="54414" checksum="3B802DF1B2B08381" modified="2025-10-08" version="1">MHRLGTVPSSSASLPNPSIPQASTSSLSSSSNDPWGVLHVNLLPLFNGEPLRIPIEDLNNLVRRHISSVVSSTPSKALSTLESDTAELLSSGMVTLNAKLSGIEDDKLISRVVELWGFFWDQVLTYVEGVLLPLQIDPLLSSLYRGPKRPSSPSRQTSGNKQSKPSLSISSSLGMSSYHIDVRTVALCSFRDKIILPLSSRLYARLSATSNMSLNKNSHQEPLQETPPRMHQMLLVLSAQSRPRPQTLSLGIAGGSSNASNLSTGEAAIADLLRVVRSASRLHYQSTFNRPSGGRPIPGSSVSSRQYHPGINNRMGISSGVGIGENSARAPNFLSEGGPGDRRGRVADKKLTIIQGRLNITSTSGADENLNGGDLDTPRNNAAMDIGMFGFTEIERQRERDFFLDSLKSPDLPPGTPTGSSTTATVTAPRASIGGWGLGAGNEPGEGGDEDEPLDWDQAQAVVERMVGMTSSHQESNGQPVLSVNSNNSHFPSAGNSVSPAPPVARRRMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ17</accession>
    <name>A0ABQ8VJ17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33834" checksum="D893ADB1798B0825" modified="2025-10-08" version="1">MITGVFVGGTSGIGRAMAQAFARHTNGNAHIVIIGRNKIAAAELIASFPKADTNAIHEFIPCDVSLITNVHHTTSELARRLQRIDYLVLSSGILIFAGRNETSEGLDDKMALSYYSRWTFIHDLMPLMQKSERGAKVYSILAAGANSPIEKDNLDLRKNHTFGKMTAALTTYTNVAFQVNLFTYDHILNKITLLEQKFAKEEPNRSFNHAFPGFVRSPMLTPSTWYWKIPYYLVYPIFSFISVTPEVSGDIHFAALLESPPGFHSYNPKGKLMQYKPAEEETVDIVWEHTLELTERLHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJV4</accession>
    <name>A0ABQ8VJV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein RAP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_316115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Chromosome</location>
            <location evidence="5">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the RAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11655">
        <property type="entry name" value="rap1_myb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039595">
        <property type="entry name" value="TE2IP/Rap1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015010">
        <property type="entry name" value="TERF2IP_Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466">
        <property type="entry name" value="TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466:SF6">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08914">
        <property type="entry name" value="Myb_Rap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="TERF2-interacting telomeric protein 1 Myb" evidence="7">
        <location>
            <begin position="193"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="275"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="453" mass="51736" checksum="40E93AA29FF19CBD" modified="2025-10-08" version="1">MTIFQGVHFYLHPEILPEVQNTLRQSITELGGQVDGNVPDRGYVLADLHNPESQRAFQLFSAERWVVPLTFVEACKTAGAHIAPIFLESEGRPMPIHVHESIANVKFRELLYEKILYCAGFPYASLESARVIMADSKTDVFNALVKHYQLTPHKYIESLEWVDKCIERQGVFFTPHVFKNPGGRRAGEERTQFTEEDEQKLCEWIAAKIPFKSTGGRTGNKLYQQLCEMSNHPEYSWVTRHTWQSWRERYKKNAGRLDKIVDKIVSTTKPSQGEKWQYGYVRQDDDKPKKKRKRLSKHEDGQEFVVGSSGTGHESVHPDPHVAANSSLGQLAGILRLAPPVNREDEWRIRDGHDPPPAWAKSRGSNELEEGPNVECAKSEEPPAISDDTLQLAITVAVAGHVLEQELSEIALQTRFTVEEVREYYDKYGGDLERTSRRLQKMREHLNAFSDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLH4</accession>
    <name>A0ABQ8VLH4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GrpE protein homolog, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_918653</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4495522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="256" mass="28322" checksum="7AF86961D3C9B507" modified="2025-10-08" version="1">MSSVYARQIFRSCSASLSSRSLARPLPSSFPCRSTVLNAKRGYSETKSTSAHEEQKKDESNDEPEKEAQPPCPDTEKLKAKEAEVVDLTSRLRYLQADFLNLQRNAAREKEQTRDFAITRFASDLLETVDVLALALKSVPAPALAAETAPASEPLASSSSSKTDTPPPKSAQEYLQELHTGVEMTQRQLLQTLFKYHVKPFDPTGDKFDPNRHEALYQAPIPGKEPGTVLDCQKPGYMIKDRVLRAAQVGVVQDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLT1</accession>
    <name>A0ABQ8VLT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="21106" checksum="C2DED815724531EB" modified="2025-10-08" version="1">MLNRDYVMQEAVRNEIDARKKANSVAFQPPAPVPKPSPLGSNTASNPRLPTVYLPSNQTRTQQTPNIRSRHVVHNSFSEVPSVVYYPLQNPSSERHYAHAQHSSNQLVAPTTQFLLNSSYTQYTSEMHYGHALNSSNQFLAPMVQSPLNPSYTHYHTALSNTSVSSNLEACPSSPHHSSDSLGIWHSSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLW9</accession>
    <name>A0ABQ8VLW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_252017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="810"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="579"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="699"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="901"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1025"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="599"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="699"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="719"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="773"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="913"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="925"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4496901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1081" mass="113674" checksum="06F8963181F879F3" modified="2025-10-08" version="1">MRQQPHRSESPSEQFAMYTELEPEQRSALNGYHRSSFTAIPNATRPSKHHATPSSTMPSTNPTIYRDAGAPVYQYEAYGLSSPTQSHMQPSLVDRPKYAGPFGLAEPYVNYNKLPHPSQPHLLPSNLNPLPMPMSSQTPYGPHLATNNVSTGVNSGHGGGSGNVPSGGNNMQEDISTIFVVGFPDDMQEREFQNMFTFSSGFEAATLKIPNKEYTAYGVSGSTNPGVAPPGLPGLTPSLASIVRAQAAINDPYNLVTMNQGGVVVDGGRDGTMSSWPTAPIDDSYYPPGLGLGNLGGMPSVGGPGITLGPNPNPNASGTTSVGNGPVPPRKQIIGFAKFRTREEALEARDVLQSRRVDIEKGSILKAEMAKKNLHTKRGVTANGGAGTNVGSVNGNPLGATLTSPSHLGPAPPAAVNGISFPGHAPMSKYDLFSSSANLAEPGSGNISARDRELGALGAMGFTMAGSSNNGSFTGTNNVPALSSLTTLWDEDNRERERMVYDAMGLGISSGDESLGLITAKEVGRRQMETWRDDRDRDRDERQPLRLRSGSAFDAFHSIPASLLQNSLVSPPFQKAKPLPLSSLTHDDGVPGPWDHFSKSSAGSNAPNSASSKVSHSSSDDTKGSNGRSRSSRSSSVAAGSTHSRGSARDMNGHDDDDDVHTNPEMEMEDSNTTVKEIDVAQIARAVGSLAVTTNKHVSHAGSTGANTVNGGHSLGHTSPQLPSPSSGSGTSVSALSAGGASGISPSAPMSSSSSSSSMRHALPLNQHCPAPNFTTQHPGSNPNISHLSSMLSSTLPGLVSGVDQNPPINTLYVGNLPISPPPLGYPPDILEESLRELFRTRPGYKRLSFKQKSTGPMCFVEFEDVDAATKTINKLYGNTLNGLVKGGGIRLSYSKNPLGIRTPTSANGPGPGFQQQHFQQQAHVGRDGDRERGDRYGYGGTQALSPTPHHHSVNYRPSHTHEFMISPPPPRFAGNSSGANSLSNISFGNFSSTSFSGVNSQLVGSGSNPMFGATNSFQGGTGPGVGYHLLPSDPYGDAQGQGLNTSFSPFDGSHLDHPQMPPMSSLPMQHGPNPSQNQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMI8</accession>
    <name>A0ABQ8VMI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_901476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="15967" checksum="5EDF1923DCDEB685" modified="2025-10-08" version="1">MLKLEDMKFPETLDAKIFYSMCKKHISAAQLQFQGLGFLPPKISALEDKFHVLGGENGKVATLIGIGHETLLLSRLPGEEEIRSNIFDNNDPAIVISLAQSMAIIVLTALLLDVFELFPWHSVRKSSVGSNVKLRVSTEAARTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMR7</accession>
    <name>A0ABQ8VMR7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Gamma interferon inducible lysosomal thiol reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_822024</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046737310" description="Gamma interferon inducible lysosomal thiol reductase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25706" checksum="06207FBD0A79D2C6" modified="2025-10-08" version="1">MTRMTAFTFLAFFANVLLVPATVLSFIQDATQNVLSDAKVDVDIKVPVTLGVMSRCPDALLCENSMDAVLKKVGNKIDLKLVYIAKINSSEPDFGATCMHGPEECAGNVQQLCAAKYSPFANWWEFVQCNNYEGRNKIGLPDTARKCAHTAQIDLETSGVGECAGLDASGKGAEGVRLLHKSVALGKTMGLEKSCTIYINGEKVCVHDETWKECENGHTVSDFTRQINEAYDKLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VND4</accession>
    <name>A0ABQ8VND4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_827562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="71" mass="7887" checksum="BF8C5E6D33D6A2A9" modified="2025-10-08" version="1">MILRTTFSAEDLGKCAGPKFTGGPDDSTRRSVNMMKMYHYTYRCACACVCSSHSTVAHQESRTQTRGTSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNW4</accession>
    <name>A0ABQ8VNW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Early meiotic induction protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_157798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021475">
        <property type="entry name" value="Pants/Emi1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052:SF1">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11326">
        <property type="entry name" value="PANTS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="14108" checksum="2B144C88CCC563C5" modified="2025-10-08" version="1">MSQSSADFEKVVKQEEAYLRLVHPTPEETPTCINLFDTYLSCNAIRSQIKSFYRYGERTHCSQKLEDFKFCLGLTRMEPEERRDVWIRRRAEWWAQRRLGKSSEDVWEIRRTAKRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPJ2</accession>
    <name>A0ABQ8VPJ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_704838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="89" mass="9993" checksum="833816E752CCB676" modified="2025-10-08" version="1" fragment="single">DILKACTIYVDVWMSHGENTSPLFYDIAKSLGAQVSVCTHSFEILLSTLVRLALNRKRRPQVVGAAWLKDCRDAATHLGEEPYLVDMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPZ3</accession>
    <name>A0ABQ8VPZ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_894659</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="114" mass="13032" checksum="A9DB69703FADFB11" modified="2025-10-08" version="1">MSTSRDRVEDTYERQNDQRLDDLHSKIRTLRGVTTDIHDDVERQNLMLDDTSNTFTSFANSLTQSSRRAAHAFGLTSGGVKSWRVAMYIVGAFLSLWIMGKIWWWWSASGETAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ67</accession>
    <name>A0ABQ8VQ67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_900930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27209" checksum="5F249E3274CAEA81" modified="2025-10-08" version="1">MASLPCCKLVFGVSESPINSPIIAAGSHPPWIGDFYESEHFLAEADKETFARPLNVQCGEKIQLNRLDRGEHNLGLYNLRGDYKGHPASTAVVKILPGPTDRRAWGEVEALQAVGQYIDSGLLQPGNRLAIVMKKVEGEIITCTKTWAESDETKKKVLLNQMKVFVKKQFKDWVHEKGMAYVKGSIRSCGLVDLGYYGVFKVESPESVTDSQIDEFFKKQWKNRMKVVNLIDGDKILNGTAAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ92</accession>
    <name>A0ABQ8VQ92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_186215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052479">
        <property type="entry name" value="GPI-anchor_Adhesion_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185">
        <property type="entry name" value="SERINE/THREONINE-RICH PROTEIN ADG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185:SF1">
        <property type="entry name" value="UPF0619 GPI-ANCHORED MEMBRANE PROTEIN C1322.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046694216" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="142" mass="14835" checksum="437699F7A0AB4B6D" modified="2025-10-08" version="1">MRSAAALCLAFAAGAYAYTVTFPTETEGWTNSGAQVLSWTRVDTDALNFTAVLVNNDASILSDPQILAAQVDGTLGNTTLNPPSGGWPSPDGGFRVNLVQNTTELNTILAQSPTFNITAASSSSSSASSTGTCFWYNCGSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQA0</accession>
    <name>A0ABQ8VQA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FUN34 transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_894926</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="207" mass="22133" checksum="C7E3AAE4C027AADC" modified="2025-10-08" version="1">MSHGHSYGRTTSGNGRIASPGPAGAISFAATALLLSLFNVQAGGVEHPEVLVSMAVFTGGLSQFMAGMWEYPRGNVFNATLFSLYGSFWMSYATIFIPASGILAAYEDPLELSHALGLYLITWTIVTAFFLFVVIRRNLALTIMLSTIFITLVILSTSQYSLAGMPIVQKAGGVFGIIGALLCFYIGVSELLEAELRPIVRLPLGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQG1</accession>
    <name>A0ABQ8VQG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_218511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045397765" evidence="2">
        <location>
            <begin position="31"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="26793" checksum="6C4277575A16140A" modified="2025-10-08" version="1">MYSSLCNIPLRALVIIFLCAAQIGLTPVEAAPVDLSDIVVLPHTQTLSPTPTYLFEARLNTPAPAPASKTPSAMITYPTTGKPPRRPLTSEVVNFHIRKLLNDFAVAHLDAVPPTSQTNLNAIWIKYSDKWGGRPKYQDDNYMEYTLKFVVSGAKEQSRDGEYAGSIVFVQTGRPDKGRRALSYNGTVKDGKGTVVTEVKLGKLINGHTKSISAALGAIDHKGTHGPTSRDSDKDIPAHAGSKDPTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQP9</accession>
    <name>A0ABQ8VQP9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_916202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02205">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="381" mass="37902" checksum="C90CBABE7DCFDD93" modified="2025-10-08" version="1">MASSELLAQIQAGKGLKKTTTRDRSAPAIEKPKGGGGGGGEISAGVSSAGPALGMGAGGPPQLGGLFAGGMPKLKAAGQNNLAKPPALGKPPSVPRATPVIPVARAPAPSARTPAPARAPPPPARAPPAPARAPPVPTPSAPHPPARAPPAPARAPSTSTPSPPDPPVRTVPPPRSWPAPPVQSAPSLPSRKPPAAPARPSPTPPSRATPPPPMLPHRSASPLSSLSRLPPSIPSRKPNALTTPGRAPPPPPPRPSSVVVSSPAKSPPPPAPARKPPPVAPPPRESRLSTPPASVGLAPPPPPPAARPRVASSPLPPSRPATNGVASAPAAPRRQIPSPPPTAGSHIFPVSDFPPPRPFAAGVRTYPSGRQRGSDFDLGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR09</accession>
    <name>A0ABQ8VR09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_894322</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046109122" description="Glucanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="454" mass="48060" checksum="E3C783B8FBD87C87" modified="2025-10-08" version="1">MFNFAALFSFAFFAVAYSQQIGTLTAETHPPLTWQECTASGCTTQSSSVVLDANWRYLHSTTSSTNCYEGNTWDTTLCPDPTTCAANCALDGADYEGTYGVTASGDSLTLKFVTTSEQKNVGSRLYLMAPGSTTEYQAFKLINQEFTFDVDVSQLPCGLNGALYFSQMDADGGVSRFPTNKAGAQYGTGYCDSQCPHDIKFIDGLANIVDWTPSTNNPNTGTGATGTCCAEMDIWEANSISAAVTPHPCTVTEQTSCTGTTCSSPNSTAGVCDQAGCDFNSYRLGDTTFYGPGMTVDTTQPFTVVTQFVSSNNETTGTLSAIRRLYVQNGVVIQNSETNIPGITTTNEIDATFCEQQKTAFGDTDTFDSKGGLSGMGDALSAGVVLVLSLWDDYAVNMLWLDSTYPTDGTTAGDFRGTCPTTSGVPATVEAASPNAQVIFSNIKFGAIGSTFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR63</accession>
    <name>A0ABQ8VR63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrolytic ATP binding site of dynein motor region D1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_915986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="3">
        <location>
            <begin position="228"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="350" mass="38818" checksum="013C99E74C1B50BA" modified="2025-10-08" version="1">MAMTRPDRELIAQVMLFSQGFRTAETLASKIVPFFNLCDEQLSPQPHYDFGLRALKAVLASAGILKRERLSSAWEKADADDAAIGLSDAISEQIIFIQSVTETIVPKLVADDVPLLTNVLGDNKLLTLPNGERLNLPPNVRIMFEVEHLKYATLATVSRCGMIWFSDDIVETSMVYENYLSTLSTTPIDSDEEDAGDALARRNNEVLPSDAAASAALETQKQVASILERYFSEGDLVSSALAFADSIEHIMDFTTTRALNTLFSLVNKTVRNIIEYNFQHPDFPLPPERVEQYVTKRLLVSIVWAFSGDAKLDLRAEMGDFLRNHTGIDLPPLLPGSSLIDYNVQVSTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR92</accession>
    <name>A0ABQ8VR92_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_724675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707:SF60">
        <property type="entry name" value="ACETATE COA-TRANSFERASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="KETOACID-COENZYME A TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="60" mass="6767" checksum="7321CE5915E535C2" modified="2025-10-08" version="1" fragment="single">RYRSQKFSTPMAKNAKLTIVETEETVLVGSIFPNSIHLPSVYVDRIVKATVPKHIEIVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS70</accession>
    <name>A0ABQ8VS70_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_814908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056775">
        <property type="entry name" value="YABBY_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04690">
        <property type="entry name" value="YABBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="114" mass="11999" checksum="40E496229794D320" modified="2025-10-08" version="1">MPKASSTSTSKAASKGANAKTSKALKEKRPPSAYNIFVSEKIKSWKASNPKANAKDAMKAVSVMWASAEENPNRGKPPKSKKAKTPRNISSPPRSSSLPAADDNDVPSSDSVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS72</accession>
    <name>A0ABQ8VS72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_864018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="23280" checksum="159490560B119B84" modified="2025-10-08" version="1">MPSTRSSERERTSIARAEVTSQFDLSPTRLIPVCRRKYGHRAHRCAAAATSPLPLDSISSSLEDISSPATMEHASPRDATLSLPDVEDFADQDSRKQSQRSYAVLKKELWANCRVACVLILPFNLGCRTHCGHVFCAGCMKKQRRESLLNKEDTNCGSCGVKLVSEPVPCNALQDSVNTFARMEDITVPKEVKSVWIRRTGGFSKSHLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSU5</accession>
    <name>A0ABQ8VSU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_138734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046574857" evidence="1">
        <location>
            <begin position="22"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="175" mass="19795" checksum="983C1E22DF07D19B" modified="2025-10-08" version="1">MSAAYSSTLILILTFFLGVISFPMTLPSHDNQLEARMPPVASARLNNLHLRLMRSSVSSSGEILMIGGTNSKNTKQTDPDKRNASELMIFKPRLTGRRPKRKQSTLPNSRPLNSTLLRIFCTDVSPFYSRIACFTLQMKKMKRRKPSWQLFQNGIDSIKQCYKWKVLDEAAAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT16</accession>
    <name>A0ABQ8VT16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ASST-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_820721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046970006" evidence="1">
        <location>
            <begin position="24"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="531" mass="57016" checksum="FD02EDBB3E41ED9F" modified="2025-10-08" version="1">MLLHSLSTFALLTLLSLPLSAIASVAYCNNQDYESGALGESPYQSYNAAPFQPVQLNYALPTADCPSNSQVSGYFMISPLGTGLHMTGGGYIMNPNGTMVYFSSGFGSVVILRGVFTYQGEDHLGIWVSDGSIPTPSGHGSGWNILLDRSYNTVATITTSGLSVGADLHELHITSNNTAIITAYPTDETDLSAYGGSTTGYVLNPVAQEIDIATGEAIFTWKALDHVSPSECYAPFGTTSTGYGTATDPWDYFHMNSIQKNDDGTYLISSRHCHTLYLVNSAGEILWRMGGKNSNFTLNEGANFTWQHHARFRGSGQLSLFDNGATEWEQDIPYSQGLLLDYDESAMTVSLLSARAPYDRTNTVSQGSVELLSDGTSVVGWGAMPYFSGHDTDGNIIWSAQFAVASSGIASYRVFLNDWTGRPSTPPSHKVTSPFSGNITVYAWWNGATEVASWELLGSRLLTPLKATSLSNASKTDFETTLVYSGSGYAYYQVAALNANGQVLKYSNFTALDGTTFGPADNQTVTAAPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT29</accession>
    <name>A0ABQ8VT29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_756358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16982">
        <property type="entry name" value="CID_Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045154">
        <property type="entry name" value="PCF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054127">
        <property type="entry name" value="Pcf11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047415">
        <property type="entry name" value="Pcf11_CID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921:SF3">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21936">
        <property type="entry name" value="Pcf11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="38"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="627" mass="68844" checksum="5589C5F727152858" modified="2025-10-08" version="1">MSLYYGQPSYGANAFSQPTMPNHYPLVSPPPVMPMYMDPATFRTDFSNRLAELTVNSRPLIQNLSMMAHDYSRFADIVAQSIEAHIRKVPPWVKLPVFYLLDMISKNIYEPYARHFARFVIPLFVDTYQQVDEATRNKMVELVLTWRTGSPTGKELFGLPAQVQIERSIWGDGSNSVGQITKAQVLSELEFTLGQKERAVQANPNDFTSKNHVNVLHQLRKMVEAGVSQNDLQQILNQLRTLMRSNVQSSALPPPPPVHPQQWSSTSYPTTPASMPLPPPAAVPVTFNATPAYPLPNLKSETYVSANLSSGTAPTPIPTIAMAGSSTQTPDFAGLLSSLMKAGVVTANSAPTGAGATARDDSTADMLEAVTQSRETARAYRKSVLSHSAQLTAAAITKTRPPIYDLLYEQLGAQCKQCGIRFLDTADGKKALEDHLDMHFRQNLKANQNIGRGHSRSWFISVEDWVHDVKGKGRADGSRPITTKAAAAAEVAARDAKLRSEFVVVPPGDEAKVLSCPICKEPLKSEFVEDDEEWVWKNAVKKDNRIYHATCHAEASSNVLAVRLRSDINSRSRSGTPESNSSSMTRLSLSPDPVTRGIKRKADDESSSLIGEAEDSPHYKKLALSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTG1</accession>
    <name>A0ABQ8VTG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pre-mRNA splicing factor component-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_817624</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="48"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="100"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="220"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="416"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="499"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="754"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="243"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="791" mass="88045" checksum="5C194577EB4A02DD" modified="2025-10-08" version="1">MNTEDEVLKAAIAKYGKNQWARILSLLVRKTPKQCKARWYEWLDPSIKKTEWSKTEDEKLLHLAKLMPTQWRTIAPIVGRTATQCLERYQKLLDEAEAKDNEELGLTGPDGDAGPSADDVRRLRPGEIDPDPETKPARPDPIDMDEDEKEMLSEARARLANTQGKKANRKARERQLEEARRLAVLQKKRELKAAGIIMRHKTKKKGMDYNADIPFEKKPAPGFYDTSEEQARVAAAPVGQTLRRLENKRKPDAEEAERKKRQRKNGKEGEGPGHQTKFIPARDAQIQKLKEAESISRSRKLMLPSAQVGEAELEEIVKIGQAGENAKALVGGGSDASGRLLSDYEGLENARMARTPWTAPQEDNILSEARNLRYMSIAQTPLLGEENTPMHTNTGGGTGFESATPRHQVAFTPNPLAIPIRSGTGDVSATPRDMSVGSTPLRTPWRDNLSINPDGFPSIGDTPREQRLQAHSAKRALQTGFMNLPKPAYNFELLVPEEENEGGDGEERGLLLSEEDAEERDAKLRRAREEEEKRILSRRTQVVRLGLPLPANFDAATLLEHLSRYDDVEEGELGAAQKLGDAELASLIQHDSLEHPIPGTSRPGGAQSTYEIPNDESIHAANEGLIALSKADSVDDHASWASVRQSLTFDSSSKTWVNHSQLSSEQRIAGYDALLSEHQNTMGQEAQKIAKHEKKLGKVLGGYQARSQAISKRVTDAFAELQTTYSNYQSLVRLQTNEAAVGPRHVDTLKVEEVENLERREKTLQERYAELAAEQKESEAKVTALEEKLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW21</accession>
    <name>A0ABQ8VW21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_817485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="19453" checksum="7396CAC5D3755EAF" modified="2025-10-08" version="1">MHQQPIQVPNSRDSNQAFPLSASTSVVGMSANHSGQSMSMQSDPNSIDAFKHNIQDILKDILHLQNVARSTLQGIQNAYHPGNSPTQTEANIVALKQELEILADKSINIGVGALPILHIPPVPTNSTNPISGQENVVPSEAQMIADATRSIQILFERIKRVQESAGTVANLLQIPAVTNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX45</accession>
    <name>A0ABQ8VX45_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_874450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF72">
        <property type="entry name" value="NEUDESIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046222066" evidence="7">
        <location>
            <begin position="24"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="8">
        <location>
            <begin position="59"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="165" mass="18462" checksum="CCC39BB760D2FDD8" modified="2025-10-08" version="1">MAFDVGTPINTALLLFIIYSVQKIVFPSTSPPKEIPNEFRSGYSWLPKSHQPTVLFKTYTPKTLEPFHGKDNGRILLAINGIVFDVTAGRSFYGPNGMYGNFAGRDASRGMAKQSFDIEMLTPIDQPLDKLADLQQDEIENMKGWVEHFSNKYIICGKLVENNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX48</accession>
    <name>A0ABQ8VX48_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_809522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="11"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="30990" checksum="A3D8B2E907A306DA" modified="2025-10-08" version="1">MSKLTSFAIIGSGNIGSFIISAFLGQAAPPSTLIVLSRNPESKNFPPEVQVVKVDDYGDINAVARILTAHNIEAVISTVGFGGISAQKKMVDAANLAGVKLFAPSEFGSPTDGAPREYRPLQERDEVAEYINAIGLPWARFYTGAFINTALFTVTGVRVNGKINIIGSGHTPVTFTSEEDAGGFIAYVLTSLPSSSISNKIFRLEGDRASLQDIAKWYHKEVAYVEAIPGPRSEILSMFSRIFESGAASTGWNFALEGEGKGWDAAGSANELWQGHQWKKIRDLVTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX67</accession>
    <name>A0ABQ8VX67_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein CPL1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_609464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048661">
        <property type="entry name" value="CPL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967:SF2">
        <property type="entry name" value="SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21671">
        <property type="entry name" value="CPL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein CPL1-like" evidence="1">
        <location>
            <begin position="214"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="304" mass="31539" checksum="487D0BA6A91AFDC5" modified="2025-10-08" version="1">MHSFACTICPAGSVSGTGGSQCNECPAGTYETGDNRHCKTCSAGTFCSECTERTYQPNFGQNQCITAAPGHYVPSKRSNTQTPCDAGSAQPLSGQKSCDLCAPGFFQAQSGQVSCCQCCAGFYSSNSGSKTCSQCGAQGTQSRGTSHPGSTSANACMAGSSPQPVKTCTQPNNDICPAVIAKTPSKRSPSQLHADSCSISVPRRHWCKVLNGGMECVDTMNDLEMCGGCLEPGHAEDLTTGARDCSAIEGVGNVQCKQGKCEIGSCRKGLRVATDGRTCVRVKLADIHKRLSHGSTGKGWAVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXE9</accession>
    <name>A0ABQ8VXE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_750370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846:SF1">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="20944" checksum="D6D66A7E4AE696BC" modified="2025-10-08" version="1">MASPTQATSNHIQSFFEQYPRFTYDPTGETMYQFRMMCRSYGWRPDSEERMQALEGVRDAIALQFNAFYGDDANSLNGWHSLYRALQVQDIPDTVKGCKEGIKTIHVNICDLVDHKEDVPTKFPSEAALAQYSRDSGKIYPRQNAHAGGLLRFLLRQIFGKYQGQQREGVQRRRGQGRSRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXV5</accession>
    <name>A0ABQ8VXV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_191400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05188">
        <property type="entry name" value="MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF17">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="33"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="202"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="375" mass="40348" checksum="9CCF073E08BD921A" modified="2025-10-08" version="1">MSQTTLPETHRILQLTSTSEPLQLKIVPTPQAGPGSAVVKVLVAGILSYSADIYNGKRQYPFPKPFVPGSSAIGRIVAVGPDATTLAPGQLVFLDCTIRGRDNSEAVILSGISEGFTEASKKLMHGEWRDSTYAEYTKFPLENCIPLNEQRLLGPVDAGGLGYCVEDLMHISKLVVPYGGLNDIGLKPGETVIIAPATGPFGSAAVRVALAMGAGRVIAMGRNETMLHKLSTLDTRISTVRITGNEKTETDALKELGPIDVFFDISPFMAANSTHFKSAIAALRHSGRISLMGGVYADISFPYLSFMHRNLTMKGTWMFSREQMFGFVKLLESGLLPLGEKNGLSVGGKFGLEEWEEAFEKARIAGAEEVVAIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY52</accession>
    <name>A0ABQ8VY52_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type 1 phosphatases regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_899135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the YPI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0650">Protein phosphatase inhibitor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="130" mass="14470" checksum="5F8DACB656DDE248" modified="2025-10-08" version="1">MSFRTSAMRRPNTSSPGDGSRTITITSTPTSEDEGSSNDASRSAVGALKLRATTRKPRQKVVWREDVVDNEGVGKKSSKICCIYHKPKAYDESSDEDESDSDSSCDHNHAGHSRMEKDFRTEILDRLFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZX7</accession>
    <name>A0ABQ8VZX7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Terpene synthase</fullName>
            <ecNumber evidence="6">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_977756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the terpene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="352" mass="39831" checksum="6B06167877F9AD2D" modified="2025-10-08" version="1">MPGIVQYQLPNIDLLLDRQSRPNYKVNPSHPELETEFISFLDKIDHAISPFQRKEIEGAQLPLCAAAYAPDADMPQLRVYLDYFVLLLLVEVMSDVSNAQAGQFDLDYMVNLLNACSDNEPFDTSKQKDTLVHLAAKFARKCFPPLSPLYRYDATQGTILYLQAAAQENHDRKNPSTFTVDSYLAHRRKVVAIHPVIAFNRWMSQVKLSPEILQTPAFEGLLESTIDLIALPNDLISYKKEKAQGEDIHNLVSVAMVDPATPVKSGDIQAALDFAGIKISEAYLRFQQCKLDAIAQTAPGDFETRSEIMRYVDILLETIDGNIVWQIDPRTVRYHVFETPEERAQWLVSICI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZY1</accession>
    <name>A0ABQ8VZY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="322" mass="34328" checksum="C6F2D32745C771F7" modified="2025-10-08" version="1">MTLDVIANMVMGTASSHGNDPMSATPVVNLPIDTSSPTLPVETDSSSPSTGSAAATTDASPTHTSSSASSDSSSKDASSSDSKSTVSASSTSKSKSTPTPHAAASRREVPGAEVQLSEGAENSDKKKKENHGNGPRKRKGDREKKHCGTGSSEKSHGGEKETSPKKQRPLAKNMGRETQPRRQGEHEEEHVPIHAGGRKPNHGDERHRRTLPGREQQHGQGGEVDHAHGGPGDEGENNAMEDGKKHGDRNVHLAVGSRRIRERERINNIVVQVARTSRTKSRVKKLLGPMIANLSVEGMKAKPRMGRRLPQASVNYGADLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0B8</accession>
    <name>A0ABQ8W0B8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_805847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="404" mass="44567" checksum="BAD333C652B55DDB" modified="2025-10-08" version="1">MAAYPYTSSQTITPYPQQQYLYAHPKAGLAASTTPGITAATTAALNFASSVTKPPSPIPSPLEPCKNWDYALKSFMESVGLTQALRGLERDMFVLNSDWENQKVPGALQELANNIQKIQQGQLEDRSLEDRKIDHVRLSNGSEPKTPTSLTKSISTFLAQKRANNEASNRAEFLRSLANLRPQDGTSSDASNMESPSSCARTDAKAIDRNAQIKYDIVKNEDGPLRRTIRSHDVSGSTTTTLLPSTSTYKGKAKATTFKNEKAETTLVKDLSSERHPGLDDRLTNIENHLAIRYVPYAPQSLLDRLRFLEEHIIKLEKDYPPWAAIHFNQPSRNWPPPPKQTPIIVPTSMSRQPKLDASSYSAPIAGAASYSGGLTRAKNSSLHRAVMERLEVHNAKLDLTGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1B0</accession>
    <name>A0ABQ8W1B0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_804955</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009449">
        <property type="entry name" value="DNA_primase_large_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="11">
        <location>
            <begin position="290"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="450"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="470"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="487" mass="55517" checksum="72C8D5A1AB8C333F" modified="2025-10-08" version="1">MFQAAKQSKLPKNESANILSVDNGSTLYRLSLYDQPPLYDVTVEEFETSALDRLRILAEIESSAARNRSWDETKQVTMTQCGKYLPLNSNSALGIDVLEERRKDRLGHFVLRLAFCRSEELRRRFIRAETTLFRIRFETDDSNERRAFLDSKDFNWISVGAEEKERYKEQLKHFISAKTDLDGAFQSEAFYKVKWTTIPDLVEKRKVFLKGGYAYVPAREQASIIYSAFEERLEAALRVTSRAIPLVDEDTRLNPILDNLAQGFIAGIPSDWVASAETTGEGITADMVDSLAKQHFPLCMRVLHHSLRKDHHLKHFGRLHYGLFLKVLGLSIDEAIAFWRKSFAGGPGSDKFDKEYRYNIRHSFGLEGRRMNYPAKNCLQLHSAHEAGCPYRQLESSPENLQSALLSSYSAQGLTINDLPEIIAQVKKKSYHVACTRVFEITHARSVRKGEGLSDGESVTHPNQYAARSIELEKETKDPKMKVDHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2V5</accession>
    <name>A0ABQ8W2V5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Not1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_785403</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="10">
        <location>
            <begin position="478"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="9">
        <location>
            <begin position="667"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="8">
        <location>
            <begin position="857"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="7">
        <location>
            <begin position="1166"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="11">
        <location>
            <begin position="1406"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="6">
        <location>
            <begin position="1758"/>
            <end position="2115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2122" mass="238324" checksum="DD210C222D6FA9C1" modified="2025-10-08" version="1">MDNSSTSTTNIHTIVKAQIVFLLSTLTEDNYERNQLEIRSLSEQHGIDTYLHFIRRLIAHSHSRLSSNNNSTAFDTSNSLTFRLLVQETQRLARDPYLAERFRDGIDKGEGEVYRSFDFVRFVDRVGLRPLERLVLAAPIVSSPTRKEFGAQAQVVIKQEFENAVLSLCHNPSFDLADLSPNQVTKLLGNLLSDPPADSPVLDASQRQALIVAAQTKYGKDTVAPMLQRILPNLSLPSGTTLVQALMQLGPDITGDADAVRALLARFGVTDAASPQDEQVIDIMSNLSRKATEGAVLCDVAALVRALNSFPNANINWAAIIKSFDVPDRHGVDTPTLKLLIAILLNCSRDTNPHAVTGFWSIWSNALYQLRLLDALLSLPGDTFNFVHLPGRRIVTVEDVAVASPTIKSLAANVQGHTWNSLDLFEVLVKLADSESTEIRNFVREMLDKAIKISAELVHMGLLQVPDAPWNEIRLEYSRKLLAMFLAGHPNHQLVFMRIWQIQPTYLTDAFRDFYQENPLNITRILDVAQDLKILEALLEVRPFGFALDVAALASRREYLNLDKWLMDNVSNHGAEFLHSVLMFLEEKMQSEKTIRLADPQPESRTMPLNPNTITIILRMLRNSQGQMADDDKHFWLEVKNHCLQVHPRLMSMMPNSEIEPGYSVINYSTETETEVDGIYKQMYDENTTIDEVIDMLRRYKNSNNPREHEVFSCMLHFLFDEYKFFQSYYPARELAMTGYLFGSLIQHQLIDYIPLGIAIRYIVDALNCPPETNLFKFGIQALSRFESRLHEWRPLCETLVQNSNLAEAKPDLVSTLQKDLAATADGITGDVQVPSVEITPVFSAIQPDVIHEVVTLPAEEIHDKILFIINNLAPSNFNTKLEEMQGLFKDEYSRWFANYLVDQRISTEPNNHSLYLRFLDSLNREKLSKFILHESFVKSASMLNSERALQFGTERTNLKNVAIWLGLITLARDIPIKHKNISFKDLLVEGYESGRSIISIPFVCKVLEGCARSKVFKPPNPWLMGVMSLLAEIYFFADVKLKYKFEIEVLCTLLDINLDAIEPSTILRTRPESLVGPLLPEYVTDIDSLPIGLYDPTGTGASSVGLGAEGGLVGAGDGQNMLSLGSSSPSDPSRALDPHIESILSTLANIAHVNSQLSPLNTQSAFKRAVALAVERAVREIILPVVERSVTIAGISTRELVAKDFATEGNEEKMRKAGHLMAQKLAGSLALVTCKEPLKSNLALHIRQFLAENSFADIAQNDAVISILVSDNLDFACAAIEKAAMERAVADVDEGFATAYDLRRRHRELRLGHYVDQNIIGPAQFNISLPNPLRIGTNGVQANQTSVYEDFGIDAKKRINSRPSSTMSFSSPAVYPLTPAADSVLGSGPNHQDAMDRFNVMTRDLEALFAQLPVNSLAVLPPNHDVRYLIRNILNAANMGERQRTPLQMSQKIVQLLYKTSSALGREVYVALLQQLCNAFEDVAKEAITWLLYAEDERKFNIPVTVTLLRSSLLDVGALDQALAKTMYMGSMGPRPSFLNFISGLIRECLSSDPPVASQAQFKYCIEMLTNTIQEGNATDQVSKLLDDLRGVRRPPMAALPDSRQPSTKPGIENMREKLLGWFQQWINIYQRSHSPEKNFVPFITQLTKAGIVKEDDTSSLFFRVCAEASVNSYLKSVAAGEYDYAFQALDAMSRLIVYMIKYHGDPSGGNVDQAKVHYLSKILSIFVLVVANFHEEQGVAFQQKPFFRFFSSLINDLHSMEVHLGTAYFQLLFCISDTFISLQPTNFPGFAFSWMCLISHRLFMPKLLLSENREGWSAFHKLLGSLFKFLAPFLKEADLQVGARDLYRGALRLLLVLLHDFPEFLSEYYFTLCDVIPPRCIQLRNIILSAFPPTIILPDPHLRNVSLDSIPEMGPIPPILSDFTSALKNTDLRGHLDQFLLNRGSPSFLLTLKDKFRYPGMTDPMPDSYNLSLLNTVVMYIGVSSVAQAKARSGTSVFIPTDPGVVSLQYLAMNMDVEGQHHLLSAIVLHLRYPNAHTHWFSALLLHLFLEVKDDKFREVMTKVLLERFIVHRPHPWGALNTFIELLRNPKYEFWNKDFVRIAPEVSLLLESVATSIFQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A1T4</accession>
    <name>A0A9W9A1T4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8J55DRAFT_520586</name>
        <name evidence="10" type="ORF">C8R41DRAFT_776965</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000028">
        <property type="protein sequence ID" value="KAJ4471685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A1T4"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000001">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="14"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4470987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4471685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="106" mass="12132" checksum="BE817F961AEEEF3E" modified="2023-11-08" version="1" fragment="single">TATGGVKKPHRFRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEAAEAYLVSLFEDTNLAAIHAKRVTIQPKDLALARRLRGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW58</accession>
    <name>A0ABQ8UW58_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_861188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:14761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="EC" id="2.3.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000157">
        <property type="protein sequence ID" value="KAJ4463617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="242"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="556"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4463617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="691" mass="75970" checksum="A9ED85039C569AEF" modified="2025-10-08" version="1">MPRSSYPTSPMALNRGSSPTSSIFKKQKHSPSSPPTAASYLSALSQADARARNAQRGTPTSTPALSLSSSLTTSTEDTVLAEEDGGNSDGLAIPVGKPPNSEQLYTTVHTEFGHCYNEEYRHISQHPQGTPVPRHVEQDPPYYILFSTYISYLILIVLGHLRDFLGKRFRAQSYKHLTPHDGYAPLNSDFDSFYTRRLKKRMDECFLQPVTGVAGRTISLLDRYTPDCNQTQIILDTRTRALNVSSYNYLGFAQARGGCADAVEESMKRYGVTSCGSRLEGGSTDLHTLAESVVAKFVGMEAAVISSMGFATNSTFIPALVSKGCLIISDELNHSSIRFGARSSGAHVRMFKHNDMEALESLLREAISQGQPKTHRPWKKILLIVEGMYSMEGTMVDLPSVLMLKEKYKFYLFVDEAHSIGAIGPHGRGVCDYFGVDPRKVDVLMGTFTKSFGASGGYLSGNKALIDRLRIRGYSGAYTEAIAPPVLTQIIASMASIMSIIDDDGSAPGVIKLGLHPSSSSSTLHQVVDYPHPGPISQRALPHWLSLPLPLASGAEGLMRLRRLSFNSYYLHRGLDKLGFITYGHPSSPIVPLLLFNPAKMIMFHRMMKDRKTPIVIVVVAYPATPLVTSRVRFCVSASHTKEDIDSVLMACDEIGDVLDLKHGLSKGERWSIDEVCRRAVELVHIPDHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWN9</accession>
    <name>A0ABQ8UWN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_860516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="690"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="463"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="696"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="933" mass="102963" checksum="3E523AE7727810E7" modified="2025-10-08" version="1">MDNFYGRSRESIADLDEILANIFASHPHAEQREDNTTVIPVQFLPDIFKALKERDLMSLTSSDEEYLQGVITTIESTPSDTPHMVDSNALLLLVAQLSTLNKVEDSTPAGSDNGQSRARGRPRALSTSSDSSSGSNGTSRYPSRPPSRSGPPPSTPTHPQTPLDKRQRSAPLSSNPPSAYTKRPPPHRRKSDASPGRGYSSGGAGGDSDGTSGPGKRSRSRAGSQSITTPSSSSTAFPLSPSGTFSPGDSPSRDRFLAESGSSSPEDSTTHLPRTDYDLVDSISRIPMPHSSDSDDSDDDQDGNTYTHFVFDPEHGPRSTTSSTASLLPGERLEALSRANTELAKRLQDAERTLSRKIGEHESELEELQYKLEELRSELARSKRDEKELRAKERTNSGQISSLESEVARLTKELSTTRDSLHSLHKQYNEQTSISERYRGDLRIREDHIRSLQDQAGLHDIEIGKMTEREREWEDRVLKLEREVEEAREGCAELVRQKTENLGLKETIDRLRFEMDDMRSGMGNGLGTIGMPGSGLNSRNNTISKSLGAELQSQLEREERERAERGDFGDDDDTEGEDTVVEEIADDNDDEGNFVTTIIKRTRRKVASKAQAELPTPKKGYSERRIEEFEDDKEYADCAIQYDPLAFFDPDSEDGFWRSESLQTEAEAPPILPVERVMTEMDIQTDVLEDEEDNLTSSSSTPTPTVPSDEPPAYPGPSTSHAEKTEEQMEKEVQAELAVLRKWHRSLEGRDVMDIKNIIMHNSSGSGLSIPKGIMKDWARVQRVAGIDCDVVERLLATAVADEDMVEDEEEEGKKESSKSRLSLRRFSPRIPHLPANLNISSYIPPTLIYSSLSVLIGVMLAPHIANQMNEPYGGATYYDRRAWTSFNNLGGGGEGFPGFGAAGYQGGTEGALWKVLEAVFGGGARYARGLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY30</accession>
    <name>A0ABQ8UY30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_898501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="51"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="174"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4465486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="373" mass="42045" checksum="FAC8F77ADFF2C647" modified="2025-10-08" version="1">MDRGTPSQLPASSIKYHHSYFTPAEVEIMSEKQRGKMTVTQEDKIRQNACGFIDAIGSRIGFPRRTIATGQSLYHRFHLFFPRKDFNFHDVALAALYVSTKMHDTLKKPRELLASSYAIRFPDLLSKSKSPFGEVDIDTVDPQLVEHDRQRLLAVERLILETICFNFTSRMPFSYVIKMGRALGASKQLTKLAWRLAIDSHRTFIPIEYPPHTVALGSIYVAAILGSFEQPEGEERQENLKLAGSLGQRGDWEQQFQAHLEDLEAIAHVMVDLLIQRAQTTANTSPATPSSPSPHPSPRNAYLSSIQSNPTNPYNTDQLIRLKIAMRESDHDPRPRESWQDPDSASAVGREVIGRNEGTVRFLFEPPGFAGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYE7</accession>
    <name>A0ABQ8UYE7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_926315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="42013" checksum="E49437B26B84B06B" modified="2025-10-08" version="1">MQNPALSSFSISAAFPHPVKQDEITIPRSLLYIIVSSIFISFLLLIVSLLDLGYCSLWLTPPLCLFTLLYFTGVLVLSRMERTIEEPTYFPTVVFVGYIMTIIWLVSFILTVIVFAAYPHMVDALRQQGLHTASVGLQRFQCLLCMTNLGLVGGFTARSHVIAMEEGDPENWRILIEKTQNPAANRPIRVHHQVNLNDPSMIQEPREAPAPTIQPDWITAAVLEDNMSVAPRTPKPPSSPCPQIEISPPGPVDDLYDEAYMSDYHREEVPEHQVSPRAPHSPFAPRSARGKLDSEYSEKAHFERAYSPRQPVFSPRLVHLPPSPLPPSSYHSHPTPSDTDSFYDDSETPETPDRWSDEDEVEEEYHAAHLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYR0</accession>
    <name>A0ABQ8UYR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_872433</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000165">
        <property type="protein sequence ID" value="KAJ4463445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF19">
        <property type="entry name" value="DUF895 DOMAIN MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4463445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="50943" checksum="CA609AEE7918B07B" modified="2025-10-08" version="1">MKDIAEGTTIPQLKNDTASEQEMPKSYPVHWFRGTIFQILVVGGVFFCAPGMYNALSSLGAVFMAFFCLIGGIIVGKIGVKAALLISSMGDIIYAGSLYLNSKNGTQWFLMFGSIISGCTDGLMYTIEGPIITSYPEPHRRGRMLALWVFMRTAAPVIGGAIIFGLNSSLDSSGGVSLETYLVIIGIMCAGPFISTLLSTPEKVQRKDGVKIRMRKAGWSQTFSEWYKVVCSPDILLLCPLFFTSWFYGSYIGTLQTQYMNVRTRALCAFMIPWGDIAGGLLIGYFLDNRRMSIKQRARWSWIGLMVLNLALWTWTAIVTKQLEDEQPVIDWTSGTLFGKTFILFVLFDLATMATQTTLYWIISQMSDDFVALSYMTGTLRGVECAGQAVAYGIKSSDTTDWLSIGLNVGLIVFSLPFAWVVIRKIGVVDFEKISFSHFVHEDKLETVDDKSIDDKGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYY0</accession>
    <name>A0ABQ8UYY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_985376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000135">
        <property type="protein sequence ID" value="KAJ4464719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="669"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="16"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4464719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="700" mass="79221" checksum="A727DDAC6D6C3F85" modified="2025-10-08" version="1">MQSILLRLQELTEDQNIILNEVNDSLREELKNKETELKKTGHRLAEAEAFKEVIAEKLKSEQSTHFNLKERYELLKDSFEEQKQELEKKKSDLNSAHKALQQTAAENTTLVVEKERLEVQIASKYKTLEATLAVEQAKNQELLAERTKQKDQAALQMEMFCTTCKAKENIMQMEGKSTQIKQEQIHDRIQGSNDTTLQQSKIRQLEEELQLVTEKLNEADIRAKLYQEKYKHMVMEKKALANRNDLHLQAPTPIPEPTGNTPICPADAPPINNHSRPRSHSLTPTSVALECHNANDPTPLVASPLPPSVSESLAAPGITLAQLYSTSPASAQSHISHTDAVGQASGTIHASVSPPRIAEPMTDPDCVDGLRDMSQSPECISQENLLQTVISTVSDLPQCTQLSDGKKRLPVAPRSSKLLDCLRDAAPTYHWGPGTIFFLPGRLLEAGSQHYVVVEPASQLIPNTGHRIHSRIGDYIGQTRDLFVTDNEWIFYAGSYKLFKIGKAPSAAFKFSDFHDITLTSLTNACMPKNHLQAFPREQRIREWIEKGVIKLDCIGLQCVNFNTSLSTMLIQHHDEGVRKRKREESEARERRYGPRMRPEFDYYERSRPLARLPRSRSRSPPRNAYEDGYQMPPSRSRLPAQRSLGSPIDTFFPDREVKSLLTRLENGLFGYTISLFEMYLLFPLLLIPASVLTQTQIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ80</accession>
    <name>A0ABQ8UZ80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_856580</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF1">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="11">
        <location>
            <begin position="155"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4466737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="576" mass="63449" checksum="CD1B9D1828BB69EE" modified="2025-10-08" version="1">MSYPQHALEASSTASLLRPSESNLRDDSRYSTGARSKMSSVSNKFSLPADPAAWGTNVSINYHESDDFLHNPDVRKGKIVDHVGSIFTSRGLANLGFLLLLCTGLLALFIGYPVLTYVSNIQTTTAALNALGINGTGQVPEIGNFGLIDLETPDDAYTKTSNRDGSEWQLVFSDEFNTDGRTFYPGDDPYWEAVNLHYWATNNLEWYDPAAITTENGSLVITFSEKETHDLNYQGGMMSTWNKFCFTGGLFEASVMLPGINNVVGMWPAVWAMGNLGRAGYGATLDGMWPYTYDSCDVGTAPNQTKNGLPEAAVQDGGSSSDYALSYLPGQRLSRCTCSGSSHPGPMHSDGTYVGRSSPEIDMFEAQVTDELGYVSQSAQWAPFNDFYVWDNTTDNLIIYNSTASELNSYIGGDTQQASSVVTETNQLCYELSKAPCYSTYAFEYKPGFDDAYITWYSSGTPAWTLNVAGMGADTATEISARPVPQEPMYLIINLGMSENFGTVDLEHLTFPNHLRVDYVRVYQDPSNINIGCDPTDFPTASYINEYIEAYTNPNYTTWVDDFKQTWPTNSYVDSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZX9</accession>
    <name>A0ABQ8UZX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_737171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000136">
        <property type="protein sequence ID" value="KAJ4464701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="14638" checksum="7FB48FD5A3CD1E63" modified="2025-10-08" version="1" fragment="single">PYAKKMMAARKYVPLWYFLPDAATEAKEQSKESLDTNHLQFAVEDGGPITGSSISLVGSHSVRASPNAIPDSQLSWSQVMRAKSAFLNALQLGTWPDSFIAMFASFYSNIDMHRKLQEQDGDRVMAHYHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V051</accession>
    <name>A0ABQ8V051_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha N-terminal protein methyltransferase 1</fullName>
            <ecNumber evidence="5">2.1.1.244</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">X-Pro-Lys N-terminal protein methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_860858</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54712"/>
            <dbReference type="Rhea" id="RHEA-COMP:13785"/>
            <dbReference type="Rhea" id="RHEA-COMP:13971"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138057"/>
            <dbReference type="ChEBI" id="CHEBI:138315"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54736"/>
            <dbReference type="Rhea" id="RHEA-COMP:13787"/>
            <dbReference type="Rhea" id="RHEA-COMP:13974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138059"/>
            <dbReference type="ChEBI" id="CHEBI:138318"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54724"/>
            <dbReference type="Rhea" id="RHEA-COMP:13789"/>
            <dbReference type="Rhea" id="RHEA-COMP:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138061"/>
            <dbReference type="ChEBI" id="CHEBI:138317"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. NTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.244" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000152">
        <property type="protein sequence ID" value="KAJ4463817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008576">
        <property type="entry name" value="MeTrfase_NTM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753">
        <property type="entry name" value="AD-003 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753:SF0">
        <property type="entry name" value="ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05891">
        <property type="entry name" value="Methyltransf_PK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016958">
        <property type="entry name" value="DUF858_MeTrfase_lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4463817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="303" mass="32913" checksum="070E20679EEFDE52" modified="2025-10-08" version="1">MATTNNLQVPVVEDGIRYWNEQPASVDGVLGGYGTGSLPRIDALGSRLFLLHLYPELCTVSSALKPLEAHPVSNPIRALDVGAGVGRVTSDVLLHLVDTVCLLEPVTPFIQEALQNARKSAAANSSTQINGRHPIHWPGLAEQTKSVTFLQGTLQAFDPAHPIVSNDSSSSIAFIDRIGSHPDPEDPMTDIDSGFDVVWCQWCLGHLNDIDLVAFLQRSYVALRNHGADGHNGNSLIVVKENTCSDAEDGGLRTVFDEQDSSFTRSDMAWKAAFREAGLRLVKEQVQEGLPDGLYVVKMYALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0G8</accession>
    <name>A0ABQ8V0G8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_779121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Copper-fist" evidence="1">
        <location>
            <begin position="132"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="283" mass="32593" checksum="7A6FBC46B2C1B6D5" modified="2025-10-08" version="1" fragment="single">MSPDRATWAYVADALIAHHTPKTYDNIDEYSKINIFLQSWNTDVRKLPKDLQDMIKVAKKHNLRLDGLAFSRDTIRQMPLWLHSECKEIKSKHNNPLSKCLRENHKVCLVRDAETFAKHSQMVRHQDRRNCACASCTQIRRATECRHPNRCYRKARELLLMLPPKWNPMHKIPTDYEPSELEQPLIEDGQTFNWRVTSRGGITDAFRIFTEGEKCNTLPDTERTVTNTYRPIEAFTDGSCMHNGTDDASAGAGVFFPNGEYSDCTIRLPNNIQQSNQTAEIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0K1</accession>
    <name>A0ABQ8V0K1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_729199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="166"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="211" mass="23581" checksum="D3C2A7D24B5656C3" modified="2025-10-08" version="1" fragment="single">LLDAFRAHYAQFMSVVVQVHTEPTDPFLLQLLGEDLNQFAQLAHEHVAIFEPEEAQTLQNSLQVMILDIRTLHERSIESSHSGRPEVVFTEYTGHPGRPRTVINPDFLSFAYRHRSTSALSHFLDIPRSTLRRRLLECGVASPGTNPFATTSSSSGYITNISDDQLDSLLGLIRWGIVIHGFIDGYSRLITGLRANNNNHGQTVLSLFLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0K2</accession>
    <name>A0ABQ8V0K2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_778893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="220" mass="25734" checksum="4CC084BFDEE5EBBA" modified="2025-10-08" version="1">MEHARGEGRGSYLWGRSVHNVRIERLWVDVSHYCSQTWHDMFTLLEMRHGLQVSNSNHIWLLQHLFLPVINEQLAFWAESWNSHRVSQRCGPARSPEDMFVFDSLVNGVRGDNLDQFAMSDEELEVFGVDWEGLQDETLLRTLRMHYTHEGSGSWLGRRGPPSDLNEVVVSPPSTLLTQEQLTFLNRQLQHHIRLPREQEVIQLWIDALAIAKFMYPDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0S9</accession>
    <name>A0ABQ8V0S9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_95885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047166526" evidence="1">
        <location>
            <begin position="24"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="163" mass="16685" checksum="9FFD62DCDCC25F83" modified="2025-10-08" version="1">MIGMTYFLKLIAFVAATAFVVEGQSETHTVTFQNLCSTGVPTLKTYDGEILSTGPAYTSNGSLIAAIAYLDVGCGAKGEGCTLIETTLVNPASPGTGSSTDINLIPPHSFSVSSGFGYYNGCDGRGANCTDADCPSAFHSSTEGGVGIVCLAENVNLAITFCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1K7</accession>
    <name>A0ABQ8V1K7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_871308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="31702" checksum="9356A6370C922D79" modified="2025-10-08" version="1">MSDFFRALSPAIQSFAGSSSATTASDRRLSGAFHLLASAVNVNEVLATLPDTYRDVLTGPLQGVRATANRLCSARKSLASLEAHKASGTIPPSIPKTSLDLQLTAEFKSSADGLTVTKAVSDLSSEFRQKLFEQTILAKSTEISVLESKITPRKLLTELSPIISSNYASLKDRMKRAVFEDVQITNDRGQPSGETELRFVRWEESPELEPQYRDLLSNCVQYAFRIIQLVEAMFAKQEGKRKEKRELKAAADVEMTDLTQPGPSLQSTIDKAVAAQYVYRLFRPAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1P9</accession>
    <name>A0ABQ8V1P9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_782211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="166" mass="18157" checksum="75904ABC6ECCC44F" modified="2025-10-08" version="1">MQCSLVLFFHFGTSDNEHLIPGSIGGEVDQWTANPRDFSTEMDCLTVCGWETPYEKFVSPASGECQVSRNYSQALDCLVIGRTAQDHDSAWGGFNFAGKLKRDGTIVMKRESKDSTDAGLGVWIFEGNVRYGSVFAGTWRSSNSPGSGIHGIFSLGKKVHPSQSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V284</accession>
    <name>A0ABQ8V284_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_96287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052190">
        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="4">
        <location>
            <begin position="27"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4465603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="24284" checksum="154CFB0990798FEE" modified="2025-10-08" version="1">MIPTPDLSHLSAQDYEHVYEPAEDTFLLLDALEADAEELRSLKAVVFLEVGSGSGCVSAFAGKILGPSALYLATDINHRACDCTRRTGSQNKVAVHTINTSLTAGLHQRLKNSVDIICFNPPYVPTMSTEALEAQGLRGIEGSWAGGSDGMQVTNTFLEVVHELMSPTGRFYLVAVKENNIPKIQSRMECLYQLKSKIILARRAGREHLSIVRFEHTAAPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V377</accession>
    <name>A0ABQ8V377_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase C-terminal-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_595391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005442">
        <property type="entry name" value="GST_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF8">
        <property type="entry name" value="S-TRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01625">
        <property type="entry name" value="GSTRNSFRASEO"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="242" mass="26884" checksum="6677FFCD55D890C9" modified="2025-10-08" version="1">MALAEPLVLYTAKICPFAHRVELALAETGLKSNKDFVRYEIDLKNKPEWYQPKINPASKVPAIAYGGPKTTGDQPSPSSTKIAESLVLIEFVADLFPNSSLLPKDPVLRAKTRFFIDTFANKFGPALFTFQSGKAPNGAEGIFSAIEQLQDLMAPEGLAIGDGTEFTLADAAVIPFFGRMEVSLKNDFGAFPEGEGKSTWETLQTDERFARWKKYWDTAKARESFKTTFDEVTKIFYPITFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3X8</accession>
    <name>A0ABQ8V3X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Copper P-type ATPase CtaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_984919</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00942">
        <property type="entry name" value="CUATPASEI"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0187">Copper transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="879"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="908"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="17">
        <location>
            <begin position="51"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="17">
        <location>
            <begin position="125"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4466953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="995" mass="105966" checksum="5AC723177F499D5F" modified="2025-10-08" version="1">MSKLLKEIWVRTPLSSTFRSSSSGVELPVESSEPLMKGLDKEMALDEPVSEKYELRIEGMTCGSCVEAIEGMLRPQAGIHSIKVALLAERGVIEFDPKHWNVEKIVEEISDIGFDATAIPPSREDEVTLRIYGMTCASCTTTVESGLVSVPGILSVSISLVSETCQIAFDRGIIGPREMISHIEDMGFDAMISDENNATQLQSLTRTKEIMEWRSRLIWSLMFAVPVFLLTMIIPRIPGLKLFHQIHIYNGVYLSDVLVMLITTPAQFWVGAKFYRAAYKSLKHGTATMDVLVMLGTSSAYFYSLAVLGCAAFNPTPDSRPMLFFDTSTMLIMFVSMGRYLENKAKGRTSAALTDLMALAPSMATIYTDAECTQEKKIATELVEVGDTVKLVPGDKIPADGNVIRGSSSVDESAITGEAVPVLKQVGDTVIGGTVNGLGTFDMVVTRAGKDTALAQIVKLVEDAQTSKAPIQAFADKVAGYFVPTVISLGVITFIAWVAISGLSSEDSLPAMFHRHGSSKLAVCLQMCISVIVVACPCALGLSTPTAIMVGTGMGAKNGILIKGGRALEASKNVKRVVMDKTGTVTVGKLSVVGLCWVPADGAENTELYGGDPDLNGLCADGVTTRKSIIAMVSATEARSEHPLAKAIAVYGKDLLKEDGSEPDVGIESFESVTGAGVKALITCTGQKYVILIGNTAFITQSSNGSLNSSLAAFETQETNLGRTIIYVSIQRGNAHPQPLLSVSLADSPKPSSKHAIRALQNMGIEVNMMTGDGKATAIAIAKQVGIRPENVWSTMTPKGKATMITELIEKHGDGVAMVGDGINDSPALVAATVGIALSSGTSVAIEAADIVLMRSDLLDVVAALHLSRSIFAVIKRNLVWACIYNILGIPLAMGIFLPIGLYMHPMMAGAAMAFSSVSVVTSSLTLKWWRRPADSVMPDEDSADSGVAWTGLFFDSARSAVGDAWGSVRGLVSGRQTDYGYSQLPVEMSNHSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4E7</accession>
    <name>A0ABQ8V4E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_848519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="571" mass="62505" checksum="FF047F9E9218603D" modified="2025-10-08" version="1">MPKRIATPPSDINTRYFTISFPYPLNANWELKADQITFSRWIACCIKKEYLIAIMYKPTARGMVIIEVDRAFPDDEHRTLLGEHRWSEFLKRPSEEERRCCSKIFYSVYNDHRGAQKDGWKTINVLEKWFDPAQWSPNNSIIKSPYPSTHWCASPAEDRTNKKMCRPLPVAMFPPPPKPVRPVVGSSDWVQSNTAPDPKSPEYQRVIWGNNDISAAMKLNKSSTVIKPTVRLNTPSAVKIASNAWGSQGKTVATPPSTTHGPTPASVPVKPPQGAWGSRRPAVTTPVSTKAWGLPKSVAVSPSSTSSAPLSAPPAISTAVPSVPPGLIRDSASGSSSGSSLSFDWASEVEAELPIHSFSPNLNNLAGNTDTLDIANTMAKVLGFDEDEDQIAATFVDADVPPGLGFPTPAVQYDTTQETVKQNLWEDVSPVDEPKEDECPVHGVLCSKGICQVAKKKKRQQANESKNKDGRNGSSRNRGRGRGRDARDGWRRNGGERNSRSNEGDHDDNNDDDTGEASNNDRDEDGSTQVNTNSPSSSSPPGSRAVSRADSVKAESQVFDHNDLRNPFADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4G3</accession>
    <name>A0ABQ8V4G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_579167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF1">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="553" mass="61637" checksum="35C8A5ED922CCF59" modified="2025-10-08" version="1">MLRIPILEDLIGLLTRYKNRSMLPYDFNVFPHPSPTFFKITGRISRMRFLRTASAIVTGILLGGLSVTQSQCPDFTTYSASPQGNPSNGTLGLPFMRPAPACRTFNSSAVETVINDMKSRLKDPDIARLFENTFPNTLDTTVKYYNQSENLAFIITGDITAQWLRDTANQFAHYRSLLSMDSELATLVKAVINNEARYITQYPYCGAFQPPPESGLPPSLNGYATDVIVNPPVDNQTVFECKYEIDSLCGFLKLSTSYYNETKDDSFMNDNWFSAIDQIFQVINNQSQGSWDENFNFISYYNWTGSAGSLSPAVNNGGNGEPKAYTGMVGTHHRPSDDLSTFAFLTPANAMLSVELTNLALILDEAGQGTSISQSAKEWSSRINESIWANTLVDNIFAYETNGYGGRYVMDDANVPSLLSLPYLGFLEKDNPSYVATRQLLLSRENPYYAAGQNFSGIGGPHIDAWNPWPMSQISAIFGTDDDEEIMQSLYLIVNNTDGLGLIHESVSIYNQSDFTRTWFAWANSYFAEMLLDLAERKPSLIFTDPVSYAPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4R6</accession>
    <name>A0ABQ8V4R6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_851626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="117" mass="13642" checksum="E31312320CE7EDA6" modified="2025-10-08" version="1">MLIPGFRDFRTGRWLTRVVYRDGITYYIIIFIWSVVNVVAILLLPHVFENLFSSYQRVMHTVLTSRAVLHMRSKSRKFSTTRSLAIVVTQEHVISGLDDEDTQRTRTASDMELSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4U2</accession>
    <name>A0ABQ8V4U2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_557028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="138"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4474172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="21025" checksum="99E19C6FA99FB463" modified="2025-10-08" version="1">MSRWTQYDEDSYRLPEGMERIGYDSDSGKYIFRDRDGSVWQGPEGAEYGEMTRVSGSSDQEAQAVMEEPSVRADGYQPLATDIHSDAPLAFRRPVNANAYRTLAPFFLLIGVVLLLVWKLTHSGWSTPPSPCPANATTPYMVQPGDYCWDIARSHNCTLEELESLNPAADCGTLRPGAILCLPKSMLSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V574</accession>
    <name>A0ABQ8V574_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="831" mass="91171" checksum="9469A6AA68D90BB4" modified="2025-10-08" version="1">MDDAQLHHLHAALQNDNTYLGSPANCPPGQGRWEDDGQKGLKFAHPKPPAIEHPVSIVMCVVGKVSNINICMGPLGAHRVKKPDFKLSKTRKTIVLNCPAKTPFSRDWSTAEAKLNRTVALQTTEKPAFLVSELYLDASDFALQIRDSTMPVDGRIMAAVPKNEKDDDDWKEIARNYTLAFVPVFDHHGNPIPQNNIQFSLLNATVLAKFTLHIYKWAGCRVNVTADIVSLSILYTSQALPRAVGVAPVDYTRLPQTPSRDLITHPELTPPNSVDGGQPYYHRDSSHTRTAAVRTPPSANVGRRNPYPTPLSSPFMLAHPPAAPSVYSHPQLRSPATTNMQHNLAMTPISRAPTPQMHVRNSYSDACPSTGSTVAEVQNHPYPYWPRIENGAHSQNDFAAFRLTQYAPPTAMNTVWPDYESPHLTLSHDDIYHTPHVTQSPLTSPARVLASGVGGTFRGHSASTGPVTIPNGVTQRAATAPIPDLHSTPTKGSCEPEKHHPLQRAMQSGDDNTTFSGSPPSNRDIGLSIQNKEPKFTFDQALPVVGLDTQNVRNNSHIAYKNTGRWMATQGLYTVVLIASIPFELLLRIAFFTAGDKGAAHSMPLVSRGFYAATIENLYSTVNGNALTTLAQDQPTFTTYKLPAACVRELLIEGVPLAFETDTDNTFPGFISVFLSAPCSTGEELHWYNIINNLCTVNTTQFELNFSGINGSVTFEMLAIIMRLLHGNSPHLRSLKLNLAAPHLEGEHDLLQEVFNDNTVTFTALQEFSLQDAPLYIENFLRRHSTVTTLTLMPAWQVYNDTNALHCADVVPHLKSFTGTGNLVAAACDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V575</accession>
    <name>A0ABQ8V575_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AIG1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_552988</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006703">
        <property type="entry name" value="G_AIG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046">
        <property type="entry name" value="G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046:SF11">
        <property type="entry name" value="IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING PROTEIN 10-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04548">
        <property type="entry name" value="AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIG1-type G" evidence="4">
        <location>
            <begin position="48"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4474812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="543" mass="60325" checksum="25640E0353AC550A" modified="2025-10-08" version="1">MSQSVTLKPIGASIAPDTNAPVAGGKSGVTPTTRPMTIQPPWVKRTINLVLIGETGVGKTAMLDLLANVCAGIKLEDFKATHQTKSERGGSSSGSQTNVPEFYTIPCANGNEVNILDTPGLADTRGIDMDNEHKAAIANAVKKHFEVIDAVIILANGTLARLGAATEYALTTISGMFPNSIVDNIAFIFTMVSDPTSFNFERKSLPEELRKAKIWSINNPFAQWTKYQEKLAQDPPTVDEEILQEMDEGVHRSYTKALKMLGQVFQFLDKCKVQPTNSIYDLYIMSTDIEAAISNVIARMDQTENTRNGLKKLQSDKAAQEQGKKINEKYEEIINTPFYEHENTGSEHNTLCVAGNCYSNCHEGCGVGFTLDRATLGSNCSAFYNSTGTGLKRVCTICHHLAEDHQHYRSKWVKRIKSGKVVDEDAKRRYDEAKTEADRIAIVMEGVEKNIIALEKEIVDLEKQLSELCEKYNQLALSGSFIGYITSAIRLLKLRQETMKKEGADAESLQRMADRIKRLEHKRHVLEEAEKPRKQKLKALFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Y7</accession>
    <name>A0ABQ8V5Y7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_629026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="16361" checksum="897943E943F322D3" modified="2025-10-08" version="1">MSSFTWYTGIRLGIKDVPQQHSKTSPMISGPPVNDFMTHCTLTHTPNTHPRPYSPHRPSNSAPPHPTPGNHSLSQSKFPHRDFFESTYSRVIVNHSYNVKFSLLLIRDLGNIMRVAACASFPGAHEMIRACKRRAMDVRKKHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V629</accession>
    <name>A0ABQ8V629_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HMG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_970853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040648">
        <property type="entry name" value="HMGXB3_CxC4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18717">
        <property type="entry name" value="CxC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG" evidence="1">
        <location>
            <begin position="252"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="458" mass="52160" checksum="3F5437B28B3565A7" modified="2025-10-08" version="1">MDRSNHAQLQEPEIGNSVDEFVVEGDADEAYCDAVERNVVAFLPIGGSLYVVQGWSAKKKEGTRQWFHFEAAQRGPDLIPVCMCGQGDHNCIHQRYFCKYMVSDQQIEERVPERPVRTVLFHREAGSSGQVIHRFSVAKNGSGLSLHGRAIVVHEGRDEGEGLWRCQRNGTQCIHIIAAKQFLKKGIQEIDSDDELEETREEIEGMNLNHTISFKLVLPPKWCELESDVKLYLRPPPLRQVPETVSIQGGEGSCACRDGGRRMYDDSSPTFLRNCTVYTLSKAVRANIELQRYPSCERRYVGPETRSLGLFNLNNSLLFTHELLDEYTSAFTSSETPSDAWVQQISRRYQAEDNSLPFVGNNTFRAAWFAYARLINFEGDKWCERCGEAPENVIWDGVTLAYARKQLRVGLRPPTAVDADSPIRPRTVTKRKEWLEDSVARKRLHHWIAKGGFVSDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6D9</accession>
    <name>A0ABQ8V6D9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_906066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="194" mass="21050" checksum="CBD70F430E0593FE" modified="2025-10-08" version="1">MSRATTFERSYKVPKFMSPSSKLIMNCDYMTPSHHTPSSAPTSADGRWYYLNDQFGYWPTSLFKAQTKAPWPAPRPVNPDALIQHSRVISGAVWPPSHHLSSLDLTPEPGLDHPPFATIDTNEVVSDNGSISNSADSPVSPISSTDSLDTAGNLEEGSETCPIHVDNSSGEDENFIKDEEPLEAGISSTATDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6J4</accession>
    <name>A0ABQ8V6J4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_897698</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="5">
        <location>
            <begin position="60"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4472368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="471" mass="52022" checksum="846B64900E80B5D5" modified="2025-10-08" version="1">MLIRGTFVQCPKLGELVILSDWLAAVDDSGYITHFENAESSTSLELQHVQTALILPLGTFLLPPFNDLHLHAPQFLYQGTGLDLPLLEWLHQYAFKAEEKLDRDPVLARTVYRRLGQRLVKAGTGAVSLFGTLKGDTNMILAEEMQSTGIRAYVGKVSMDISSRPSYIEASSSAAVDAARAFGEKLEQTYSVTSQSRPSFVHPVITPRFVPTCSDELLHGLGALSAEKGWRIQSHMAESSDQVEWVRKERGEDDIHIFKKHNLLTSRTIQAHCTFISSSSSSSSKPFVDLHALGTAIAHCPLSNIYFSASRAFPLREALEAQTKIGLGTDIAGGYSLDVMSAMRMAVAVSRIREGERVRTVSPDHGKSLAIDWKESLFLATLGGAQALGIDSGIFRVGAPFDAQQIRLFDPRSGIGAGALDFFELEMIFTKVHEESYEKPDLTEEMIEKWWCVGDERNREAVWVQGVKIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V780</accession>
    <name>A0ABQ8V780_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_850988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045514942" evidence="1">
        <location>
            <begin position="22"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="23318" checksum="920FED9F75979A5F" modified="2025-10-08" version="1">MLAPSFLSLSSLLLLIPTTLGAAILRRDNGCNTWPSVDIKDNNASFELWAHYESRVVIPLAMTTFDGNSSGNATKAYLAPSDLGGTVVGTLFTLNNSGLIGAGSSSNNSDSSSSPNTTWISNTIDAGGFFPFSLSPDANDAGIADDYCEVPNTDPHGPLINGPLFGAQGSTSGWAICNRVDNPLFQGVVFNPASYSSDYGFNVSTCQNVTIYLRSAALGNLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V820</accession>
    <name>A0ABQ8V820_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_846454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047205947" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8020" checksum="A73864E308AFB636" modified="2025-10-08" version="1">MQWVGFIVIIMALIALASKSKVAVRKSWSAILKIFYEVQSTAGSGILCFHPTAILPKCGSIEMGKKNLSPQVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V873</accession>
    <name>A0ABQ8V873_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_843688</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="36"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="739"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="528"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="751"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="773"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4479505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="899" mass="98457" checksum="C86A6CAFADC7654D" modified="2025-10-08" version="1">MSPRAHSDPATTRSTSQPYARRPSGQPKSSRQQFSACGACRMRRVRCDLKDISIPVTGPHPACSNCKERGLKCVDEFADVKAVKLLRRGRRLQQVEAIYGKEANQNSSSSSYLGLPTRIPSTIPTLHSDFFDSAFWQWFSLQRPILDGAEFSARFCAHAKGADSLGYEGSLLAMVLVVWAASFGLDERGIPSDESSGQCDSDSLRSNNRKGGMDMVPTVRSKTNERDPSAVDEISVRRGRKERSEAMLREVLELADIHGIMRRPTWDGVKVLLLILPLLEDEHPLDRLTMHEASLSQAHSLCTLLSGPPSSMPSISSGSSESPDEALMRARIFWYAHMQEGITTGMRGGRLLLSEDDLDVFQRTLPPFRTNSPRGLNVVYTSGVGLPSPNSPTFPSGMSSDSLRDGSPHSGAHSYLSVTHLFSIPLHLSSVCRKIHAVLTGAKASRTAELGGGVDAEGMREVWEGLDTCWDEFEAIRRGISTSAGGSMLGDVDVWTERFVSCWQIFIFECHNVIRESLKQYGSSPNTPANRSPARSPSPFASPRQLHDVASRKCFRLLPCVLSIIKHHLTLTYESADPTGLFKWDTGLVRDGCFFAAFLSASVDSEQLIDYATYEPPVRQFRRFKQEPSERSSNSFGSGGGVDIVRPGLLPILDADEGTRICLAAIAEMQWAFSKSEEREEAIRIIWEDNKLKKQRQDQQHFNAVVGQHNIPSLPELETRYQPHHQQISSSYMIHGQQNGLSPLSLTSPTHSAPNSAPVTACTTDGSGANGWPSYTPPGTSSSSNGTSLSAQGSPVFTTNITTIPNSYKNDDNFYHVVGVSDMDHFSFNAPATPVDPTSMMTAYQRNTTHVSSNNGVVHNGSGYLEYAAGGTSATPVLGHTESDGCPPHFVEDVHGFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8T3</accession>
    <name>A0ABQ8V8T3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_842116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="37825" checksum="4083166AF84CFFEB" modified="2025-10-08" version="1">MTNGQDFEESAVEAIREASSNDGSIWSKIVSLVIGPRAPDNYINTINMTLQARQELRYWRKVSNFWKKTARESNINTGAPTPSTSNVSEIREILSEERKKAVQELTEKRKTLGLNTTCNAPTSSGSLSSRSNESFKLSYRLPESQPSFTSIMSTMSKSVSSCESSVPQSTDRLAPLASDLFKQDLLSSHSAQRLFSSSSHKYLWSSFAAEKQVEVISGPSEKSFGKRKAVSARVSSASTVKSCVIFADVDLISRRSQLPTSFSFESNVGQIGSSAVCHLFCMILILVPTVLPPRSTHRPRAAIYPVWRRSTLMRRVKVHRFPTSGQILNLYPKTSNPRTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Z3</accession>
    <name>A0ABQ8V8Z3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_771210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="46"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="337" mass="37751" checksum="BE85C2BDD69EAFEF" modified="2025-10-08" version="1">MSIIQAEKVVVDTPSVDGLPSLKMVVNRYTRSPSARIDPSCGNISLILFHGLGQTKEQWEPVLADLWDEAEGNADFARCYHISEAWTPEWPSHGESATLNKPVLTKNNIQGISVTVWARGISAFLMQGYLKNKQVIAVGFSIGTLAMFNGLGPIFFAEKSPPVIGLVVVEPLMFDRETSSPDHPRSNMIVKMMKKGIMSQAENWPNQEAARRYLTKQLPWSQWEQSVFESYMCHGLENYEVNGKQGVKLICSRAEEASTYGRYQESWDALSMLEQLSSIIPIHVVFGSKDKLIPREWKACVIDTSKGRKVAGVHQIEASHMVCLHSHTSALSNRMLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Z4</accession>
    <name>A0ABQ8V8Z4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14810">
        <property type="entry name" value="bZIP_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="346"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="913" mass="96265" checksum="41419EBFC1A490FC" modified="2025-10-08" version="1">MLVDPVANPSNSSISAPTNISDLEEYLNTELFGPSTSVAAMSPGPSGSSRASSPSSHSDSLSQILSTPPQPVENSFPAVDPYSFLGGLSGADGNHNFGFGFGGGSGTPSFFNFLDEEMKVDPSTNSIPFETGSPFDFMSALGLGGVSGLTIDPSTSFSPGSGSVAMAIDPQLVDSPSTHVQSDFGDEEDKEQKMEHAVVPIIGDEKKTRSQSKGLSPKISEDAADVAKEAQEKLTVTIAPVKVGGHGKARKGTVQSGGVTKRIVIPTTAPATVPMPLPVIAAPSSLSSTSSYSAASLLSRNKENVSAASPSSSTTSHLKEVDDRDKDDDDDLPADWRPPPEVFAKMSSKEKRQLRNKISARNFRVRRKEYISTLEMDIAERDRLLQAIRSELGSTQSENLALRQEVAALKRALLDGRGATSPISPSSSTSSLIRSASPALIIRGADVNLNSAAVTTGLTIDDLNLPPPAPLPERSAAEELALRAAASGASPSVSTSNATTNILTPNIKKDLPTSPRLNNAAGFWGGVSQAGFGFGGMGGGFTPVHTVLMPDLNTNMNVDGTNISIGQWVRDVLAANAANLRDGSSSPEVSPKLLQENMNPVMNVTGAHQEDNMSPSAGVHNGFEGFVDTNPFTMKSLDAYRMQLWTKMAASSSHQASHPNQSPPQQPSQPNIYSSTYAQQRKALERELSYSSPFTLPSHQPGAKSPHSHHHHHNLTTSLKPAYFVNSNKPNLPSPPPPPKMGSTLSALLAGKHSTPNAFGGSFPAIPAHSSLPSSSNLGRPALSKQQQQQQMQQAQNVMYAALASTASQTLVRRLGNAFWDAFSGSSSGPSASGTGAHSHMKPWDADKVRKVLEGKAVIKVVDVDEPVQRVIKREPSTPMLPSSSLASSDCDKSCSMTALLEDSMRTLSLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9A4</accession>
    <name>A0ABQ8V9A4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="344" mass="37056" checksum="B979E1A38FEED833" modified="2025-10-08" version="1">MKAVAWYGAQMYDTSKVFSLYLPAALNLLQNTPHLNTLESFTSNFPMNWNPHLHRNHRVIVWLVNSLACAFTLAPAVSAVKSNPPYITALGAIGAILSLGSSILASSRSSAEPHPREVASLGTRVMEAQMSADIENHLLHQKQFQFPKRQLGRVLLLDSVARTSFQRSGILLQSPLGACVAPQEVHLRDDFSAADRQTHIRTVAPRSSSLVSLSTESLPSSTSCSSFYHSFSPPSSILPLSVPLSTSPPSRSSLPSASSLLLSAPSLGSSPIVTPSDLSVHTSSETNLPSVTLESASSSPPLSPSLPANLHYVPSITSHSMSTFYLPLTMYLLHLYHLHCVKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9B6</accession>
    <name>A0ABQ8V9B6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plectin/S10 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_841488</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="87"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4481825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="150" mass="17138" checksum="6A2C238B4E2FC963" modified="2025-10-08" version="1">MIIPKDNRRTIYENLFKEGVMVAKKDFNAPKHEELEVPNLQVIKALQSLTSKGFVKTQFSWQYYYYTLTPEGVEFLREWLHLPNEIVPATHKKAPRPQRPAGVRPGGEGAYRPPRGDRGDRGEYRKKEEGAPGEFRPQFSGVGRGAPRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9G7</accession>
    <name>A0ABQ8V9G7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_774105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="5">
        <location>
            <begin position="130"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4476143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="445" mass="49792" checksum="D5E095E73CBA5D5B" modified="2025-10-08" version="1">MKVSIIDLTEDPITSAKKASSVHDVNSADPPFGSRFLVDPSLTFTQNAWDHVPPPMDQGTTIATSLARQRAAVVSEEERLKLNSKPAKYWDNFYKNNEANFFKNRKWLHNEFPDLVAAEEPDAGSVKIAEFGCGAGNSIFPVLSANQNPQLELYAYDYSNHAIKLVQHNPLYAFPPCGSIHSAVWDLSSDDSLPPGLAPASVDIVILVFVLSALHPDEWASAIRNVQKVLKPGTGKVLFRDYGRYDLTQLRFKSGRMMGDNFYKRGDGTRVYFFELDELSLLFTGQQLSKEERDRANLEMSTAEIVDGEDDDGSTGAGSITTVELAKSSPELITNSPNTILPSPFTQLSVTPSTINDSTKKFEPSSANDAEIHPNLLNPSFPFLRDDIDDTSDKDDQNKQLLSQTPRHHPLFTIVNLGIDRRLIVNRKRQLKMYRVWMQAIFRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9I9</accession>
    <name>A0ABQ8V9I9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-related protein Arp3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_886873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="430" mass="48147" checksum="B3E356DA4C8DFC97" modified="2025-10-08" version="1">MSLLAPIICDNGTGYSKVGFAGNSDPSFVFPTAIATRGPAGQSSRAPAVPSKPGHLASKRGVEDLDFFIGDEALANARTPGYGVHYPIRHGMIDNWDHMERYWEQTIFKYLRAEPEDHYFLLTEPPLNPPENREQTAEIFFESFNIKGLYIAVQAVLALAASWSSNRVADRTLTGTVIDSGDGVTHVIPCAEGYVIGSAIKHIPIAGRDITKFVLDLMRERGETATIPPEDQLRVAGKIKENFSYVCQDIVKEFRKFDTEPYKYFERYEGEHSVTGRKYSIDVGYERFLAPEIFFNPEIYSSDFLTPLPEIVDDVIQQSPIDVRRGLYKNIVLSGGSTMFQHFGNRLKRDLKQLVDRRLDASVLASGSVLKSTGVEVDVISHKRQRYAVWFGGSLLASLPEFYTSCHTKAQYDEIGPSICRRYQIFGSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAB4</accession>
    <name>A0ABQ8VAB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_896608</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12910">
        <property type="entry name" value="SPRY_SSH4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035780">
        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="7">
        <location>
            <begin position="105"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="579"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="519"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4484068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="602" mass="65443" checksum="7B630F73CE955CBE" modified="2025-10-08" version="1">MAVDQNHVDPQESTWLILLPLLIVLSTFLFLLLLFLICLLLIRRRRGIILRDSDGPVDMSREELVEGDGGFETIEARWLEGLTDDNSRRAYMRAKDYQSQYLPNSLPSDITLSQFLSIQEKGVSAWSFEPDLETLNSLLVHARTEITFLPDPASASCVQSNLPLPKLNEVYYWEVKMFDLPESTNVAIGLATKPYPSFRLPGFNRYSIAYHSNGDKSHNYPFTAQNFGSPLKEGDVLGVGYRPRSGTVFFTRNGRKMEDAFTGLNRYNLFPTIGADGPCSVHVNLGQAGFVFVEANVKKWGLAPSVGTLAPPPAYGSERGSILLDVGGRRRSPRDSSASSPSGTASPTPSRRTHRSRRPRPNSGDPIVSSPLRTAEPITPPPPITPIDEEPASGSNVSTSPRYISPTDLSFHAPPNTNLPPSPGPHDGFDSDDDDYSSAASTSRPSSPDVAGAINPFSTPRRMRRSLTHLATSLSDSGAETYIQVHPPPDSPLSPPPVTPNPHDIHLQALTRSDHRRTGSSGSQTLSSGPDGDGNRLNSSESLSRRDPPAYSPLDAFTYADGVHIDLPAEVITAALEGNTLPASVMGQGNGSRSSGRRSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAZ8</accession>
    <name>A0ABQ8VAZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="15">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_847394</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05001">
        <property type="entry name" value="RNA_pol_Rpb1_R"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="17">
        <location>
            <begin position="243"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1545"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1598"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="1545"/>
            <end position="1555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1556"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1606"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1732"/>
            <end position="1749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4475111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1749" mass="194143" checksum="4BCDD1AA69E7E36B" modified="2025-10-08" version="1">MLGHQFAFSAAPVRRVKEVQFGILSPEEIKAYSVAKIEHPEVMDEGTHKPKMGGLMDPRLGTIDRNFKCQTCGEGMAECPGHFGHIELARPVFHPGFIIKVKKILECICVNCGKLKADIADPNFADKIRHVRDPKKRMAVVWSHCKSKMVCEPDDPKEEGAEPEPEDTKKGHGGCGHIQPLVRKEGLKLFLQYKKPKDDDEEIKSMQPDKRLMTPQEVYTTFKKMSDSDLHLIGLSEEFARPEWMILTVMPVPPPPVRPSIAVDGGAMRSEDDLTYKLGDIIKASANVRRCEQEGAPAHVITEFEQLLQFHVATYMDNDIAGIPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVITGDPNLELDEVGVPRSIAMNLTFPERVTPYNITYLQELVRNGPTTYPGARYVVRDTGERIDLRYNKRADAFLQYGWVVERHLKDGDFVLFNRQPSLHKMSMMSHRVRLMPYSTFRLNLSVTPPYNADFDGDEMNMHVPQSEETRAELSQIAWVARQIISPQANKPVMGIVQDTLCGIRKFTLRDTFLDWNQVQNILLWVPEWDGSVPIPAVLKPKPLWTGKQILSLVIPRGINIHRSPDPKSSNPVFDDGMLIENGEIIFGIVEKKTVGASQGGLVHVVFREKGPEVTRQLFTGLQTVVNYWLFHNGFSIGIGDTIADKNTMSYITETIASRKANVSKIIEDATHDRLKPAPGMTIRESFESLVERELNLARDTSGQHAQKSLKEDNNVKQMVVAGSKGSFINISQMSVCVGQQSVEGRRIPFGFRHRTLPHFTKDDFSPESRGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDVMVCYDGTVRNSLGDLIQFVYGEDGMDGAFIEKQNIDTFSLNDREFEHNYRVDVTDPAGGFLPGVLQVGIDDSSLELQNKLDEEYDQLVADRRLLREFIFPQHATSFNQYLPVNLSRIVQNAAQIFHIDRRKPSDLDPAFIIDSVKTLCERLVVVRGDSPLSHEAQANATLLFRMHLRATFGCRRVLERFHLNKEAFEWVLGEVEAKFNQSVANPGEMCGTLAAQSIGEPATQMTLNTFHYAGVSSKNVTLGVPRLKEIINVATNIKTPSLSVYLEPALRFDPNLAKNVQQELAYTSLRTVTAAVEIWYDPDPSSTIIEEDEVFVESFFAIPDEEVESKLHLQSPWLLRLELDRAKMLDRKLTMAYVASRIAESFKTDLFVIWSEDNAEKLVIRCRVLGGADKDEDGTETLEEDIFLRQLENTMLNSVSLRGVQGINRVFLTKHDLVETKDDGSIVAEKDKQWVLETDGVNLKTVMCIDGVDFTRTYSNSCVEVFNVLGIEAARAAILKELRGVIEFDGSYVNYRHLALLCDLMTHRGSLMAITRHGINRADTGALMRCSFEETVEILMEAAAVGEKDDCHGVAENVMFGQMAPMGTGAFDVALDIDMLKDAIVDHRLPVQSMLAAQVDGGMTPGQVAMTPYDTNSPMWDNHLFKGSDQAAFSPLAVNSNEESGNFNYLPWGQSPRGAGGMSPGGPGYSPSSPNAYSPNSPAFAPTSPFGGGATSPMVYGGTSPYYDPGRGVTSPTYSPTSPAFNPTSPTFSPTSPRYSPTSPSFSPTSPRYSPQSPSFSPTSPRYSPTSPSFSPASPRCKSPSPAQLSPSSPRYSPTSPMASPTSPRYSPASPAYSPASPAYSPASPAYSPTSPLRSPSSPSQNGTAHRSHSYQSSPSWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB68</accession>
    <name>A0ABQ8VB68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZW10 C-terminal helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_770702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="2">
        <location>
            <begin position="832"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4481815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="982" mass="107988" checksum="BBBD014CFE780EC4" modified="2025-10-08" version="1">MAFPVPSHLPRRANPQDVTSKILSTMDEATNKSLTASLAKSWLEELDTTIHSTKERIHDRIHADLPEFERQSQTSISVQTRLHTLVTEVDSLNHSLHDPESGLVPSLVKTLTAHSTLAQKATNARIKHEALSYLLRCSKEFSSLEGLVRNGDLPEAVESCASIEQSLKDAPIALAQSDVYLDLKRKFNAAKARTEEQLSDAYSRCVLVAPHELTIAQSVQVRQSERTLSLPEILSSLSLVSLDNHLNTLRRDITTHYIDTLLTQPMSVVEEGFKLSFFPSPPNDENLESRIDNLSRTLHFLHAHLFTYLPAAKCSLFLQSLCKPVISSVLNNLLISNLPYSFNRLPSFLELVKDAVSFEQTCIIELLGNDSADRPIKAWADGVCGHYERQRRVFILENTRAKILEPEDSSNAFHVEVEVVQAAAEPEVVPIQEEGVAEDAWGLEEDDASASAKVDDSGWGFEDDTGSAKTGEDGWGFEDEVNTDDMDKIDDGWGFDTAEEATVPTGDESLSDIKPATNGHEPEPEAEDAWGLDDDATADDAPPASEEETNWDDPWGENISAPPSTSVESPRPPPAPSIKSPPKVATRLEKLANKGKKGLNGNSPMNSPSMAMAFSPNVSSPSFSPAIASPSFNAKVTQSASPSQPSLPSLPSAASKLAEKRPLDLSISAPKESYLVSTSMKDIVALVQETLREGREVGDSKLLSPAHESSSAPGSILYQTAVSILDLYRALYPVVFSGILQSLEGPMRFSNNILYLSTEIDIIVKELHGSNVQTVKERFSECGRAFKLLSESWYGDAIEKQRQLVDKILAENTQAFSSTGDQERYDECESAMNRSLQEIRRVSQKWKGLLTKSKYYIALGSVTDAALSRVVQDVLALGDIPELESHRLSELCRILLALEGLFSEDPEKPSFVVAYVPSWLKFSYLSELLEASLADITYLFEEGALVDFEVEELARLVRALFADTPLRTNTINKILSGHSVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB73</accession>
    <name>A0ABQ8VB73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar ribonucleoprotein protein MPP10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_910846</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the MPP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017300">
        <property type="entry name" value="snoRNP_Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="192"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="372"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="656"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="730"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="424"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4484095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="749" mass="84081" checksum="4408BF7D4EA5EC26" modified="2025-10-08" version="1">MSTAPTVLSSAPLLYQLSLAADQQPESLYSGDSDVQNAALQAAKFVFDLSVQSEITCKPYLETLLASVSPSDAPQTRSQARKRKRSPDPLSLEVIFKTTPVDSLFIDGMDDDQIWSQLDLRTNNICEVLDKILDKEPDEEDLEKEDSGFEEGDVEEDDEEFDEKLGEAIRRMKSGEDVDFAELGLDESLKELVLEGAFDEDEDDSDVDNDGEEEGDGSIDSEDDNVEEEVALRDSSSDRGDGLGIQRSKIDVITHKSSIQNRKRTRPGHPELDDNFFDLNALKSQTEQFEAKNASSGILDDEEQEDAEEEVDLFAPIDLQEAEEEDSENNANMLYYNDFFKPPKQSKQPSKPTTVRFRDEVRVKKIKAQGKNLPLSGLYGDGEEEEEEEEEEENIAWASDGSSEDEDADMGVEDEDDGNGAEDFADHQRDAISRVKDDLFADDEREEPQKDLSTHEKRMAALKRQILELETENVGPKDWVLMGEADSRSRPQNSLLEEDLEFDRVMKAIPVITEEVVKSLEERIKTRILENRFDDVVRIRPLDDKPFLPSRFFDLKDTKSTQSLAQIYEDEYVAAQTDGVAGDDRDGKLKKEHEEIEKLWESISYKLDALCNTHFTPKQPKATISTVSNVSTATMESALPTTQSVSTMLAPEEVFAPSSSTLRARSELTPAEKQSLRRKERKAKKKTRDALNLSTDKYARAQKGGSLKKQKEDALKSVVKAGKGVTVVGKKKKDILGKKDRNHKQSNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBG8</accession>
    <name>A0ABQ8VBG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial genome maintenance protein MGM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_921290</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
            <location evidence="1">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009446">
        <property type="entry name" value="Mgm101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404:SF0">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06420">
        <property type="entry name" value="Mgm101p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4486419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="247" mass="27615" checksum="7806C2AA3A96E404" modified="2025-10-08" version="1">MSLASRLLRVAARTNRGSTGLTSPRRLLFPIHTQRNAGYTTETPADAVKKEEFKVASEIPPPSGIADQINDGKTDWSKSYHGLSEQAFAKEVAEVLMAPVEALDVEIKPDGLIYLPEIKYRRILNKAFGPGGWGLAPRTETNVGPKVVSREYALVCQGRLVAIARGEQEYFDPSGIPTATESCKSNALMRCCKDLGVASELWDPRFIREFKAKYCVEVFAEHVPTKKKKKLWRRKDQPKLGYPYQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBJ3</accession>
    <name>A0ABQ8VBJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycoside hydrolase family 18 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_797252</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046810697" evidence="9">
        <location>
            <begin position="23"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="54"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4486402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="441" mass="48008" checksum="2CB5EB48EF0B8E08" modified="2025-10-08" version="1">MIFYFSKSFFLYLSAFSLLVSASHEHHDHHEHHHEHIHARDALQVQIRRRDSDFIAAAWFAGWHQDSTPSFGTPDISWEKYTHMAYSFAVPTQDVTQLSLDGSEGDKLPGFVQTAHQNNVKALIAMGGWAGSMYFSSAVGSAENRTAFVKTVTDFTSKYGLDGINFDWEYPNKQGIGCNVINTSDAGNFLEFLQELRQDPVGMKLSLSAATGIATFSGPSGDPLTDVSGFAEVLDFIAIMNYDVWGSWSAAVGPNSPLADSCAASENQQGSAATAVKNWNSAGMPLDKIVLGVASYGHSFVVSHDDAYMSGSTTELAPYPPFDKSAFPHGDSWDDDGGPDACGHHEPSGGNYNFWGLIENGYLDQNGDYVDKIPHRFDSCSQTPYVYNPDSNIMISFDNAQSFTSKGKFIKGAGLKGFAMWEAGGDYKDILLDAISAGIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBL5</accession>
    <name>A0ABQ8VBL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_896396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08570">
        <property type="entry name" value="GDPD_YPL206cp_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43805">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43805:SF1">
        <property type="entry name" value="GP-PDE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="17"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="36351" checksum="2C6546C2EB1313CB" modified="2025-10-08" version="1">MHSPSERVLPVLTNFSTDCWGHRGASAAFPENTLASFEAAIRDGAEGIESDVHVSSDDVVIMFHDPDLSRTTNSTGAIKDRTWYGENGMEHVRTVKEPRQAIPTFAETITLLMKPENQHVKFNVDVKPQNNPRRLFSLMHKIISAQPDWETKLASRLVLGLWHPSFIVAAKETLPYLTRSFIGSSPSVARTYFWNHCDFFSMSFAVLATSDGEKFRKECQDAGKKLMVWTVNKPEHMMEAVRWGVDCILTDVTRTWLDMRSALYADYEKTGLQYSRIFLWTTLDYWTPIQMLRQTAEVKRLQSIAGPFRIEAPVTISAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBN3</accession>
    <name>A0ABQ8VBN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_838480</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4486479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="85" mass="9641" checksum="6905219A59553882" modified="2025-10-08" version="1">MPVPWEALIPFGLVTVMFGVSGTLLNVSTRAQNLGKPVRHNIDNWDEMMMRRDEQLTGHKRGQRDDPTPPPGFETSSVWYTEKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC01</accession>
    <name>A0ABQ8VC01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_841763</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050198">
        <property type="entry name" value="Non-receptor_tyrosine_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24418">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="892"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="482"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="683"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="757"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1460"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1542"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="398"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="482"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="683"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="792"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1460"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1549"/>
            <end position="1567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4481326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1864" mass="201198" checksum="78C52F0E2CEEEA81" modified="2025-10-08" version="1">MFDTSASSKDRPRRHSVATGTPTKEGKEGKDNDTTGTVPVEQMENWEITRKRVAQAASSILGTSALIAHEILLTSVDLVELAPVPGLQAAARTLLQIWACLQQVDSNRLQCLRLTEHCADILLSVRQEVYEAGDEVEDELRLPFDKLTESFNDVHALLVKQAGRPFLKRYLKRDEISKQLHQCDVGLQEALGMFSISIQIRILKQVQLAEARRQHDTQELLRSVANLSHLSQHGYPIQPDPPSYSMPTTPVALGAPDLQTPKVSQAYSQVPMEPFSLSSGISTSARPPFPYAASSLLSLSGTRSVSTTASASASSQSLIPGLHGLPASSSHSSWSQSQSVSVDQSKDPSIEAYSWNYNSNNSSEMTSTSKIPPSMSSVKVPPEPVSPKDTSTVIPSVSITPSSRPSTATSSSTASTQIESSITTESYNAPSSAALQTRSGQIQKSSLPQPPIQLIPTKSSIESAGAMLDAIQRQGNVSAGSSEVEVSSLESSSTSTTICTVTPGVTGVESTSTTSAATSTATSTTASHTTTHPIPPALFPSASSLPPTQVLPTLLSLTRHQAALDAESDYADLRGVMRTALSKGSDVEILKVLGVGLRQARLGRGSVGQLEGLSRGRSGMGGEGGIEGSGLDAGEMAEAIKTLQRAHEAILERERWEDLQARQQEQEDVSKLAQTQLSHVSQITSQQSLEVKSREVQVQQQDNRPGVEPRSSSSSSSSIKMLSGIKRRMSLQSSRSYSSTAASLGFQTSLNETIIDEEAEGVEGDENVNRGKPEVGKLRSKRGKVGAKLMRSKTSSSSSTSSTATTNDSVLSKSESGSGSGASRSSVCGKRNDRYMREKDTLDKEFIESGIDALRRMSRSAAVQTRTKTRSHEEVEDPARLLPSWTITRYEIDREEKIGVGFFSDVYKGTWRPPSVPSAPLYPYSAITGISHTVETSPSLSFYSPYSSRVVAIKVLAETTPRSLFLRETAIWKKLSHPNVLELYGASSASGDPPWFFVSPYMRNGCLVEYLRRNSTSIPHTTNGRFGEAKVPWGLILPGNSAYGVYEAAGLGGGKGLPRIQGFDLSTSSTTFNSADIGLGLGLASNAADPPSASSASSPISPHLASRAYFRDSTRAETTVFETLEDGIESAGNIDVRILGSGVEKVPKEWDLLRFMHEIAKGMEYLHGQGVLHGDLKASNVLVDDNIHCVISDFGQSEMRSEAYRISGTALPHGTLRWQAPEIFAGSSQLTVEMDVYAFAVCCTEVLSLGRMPWPLYDDNQVQNHIMANQRPDVPPTCFTSPDLIDLIQLCWATNPLNRPLFSEVASELKALRKKSTLSAGVTGAEMIDSRFKSPRFSELVYQLQDSRSPPSPDMHPIQLLPRVQSTSVNTPPRDIHAPVRVVYADGTPSSYSSPFSNASSSEDDSFRTANEVSMSTYGVAVRGYPETAVAVSPSVASTIKAGVHASSFSTSPFAPPGTLPFSPATASSSSSPAPPPLSPNSSPYPLMPASSSLHLPGDGLAELGFKYNDDTDNSDITPATLAQSQILETVKPFRPSSSATSSIFTSTLRESQSGDGCSYDENSQVPGQEPVSGNKKVNGYDGYDLPPLANDLIAEAQNERRYRLLLVHEFHPSLTLPLWSPAPVALGAVGYLSKPKGEFITLFNAFHPQNSVINGVKSLPSVHGYGKFSTGNQRQDKRNAAQRGLDTIAGLLTFKGRGGRISKNVSRRYSYPLRVGHKTAHLCTETTMYRYVENLDAPKKWFKANVDTVLEIFGPQHQIQKEELFFVIGSLDTPEYALFVSHNHPDGQVHFNVFNSSKSPQPWGTFTTDTETPFELGGPSYREPVSCTPICSNKISPQGSYPWNTVLIARLRFKPDVLEPTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCT2</accession>
    <name>A0ABQ8VCT2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_839208</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044968671" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4484630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="677" mass="74239" checksum="D5070A827A31C3A0" modified="2025-10-08" version="1">MTTTSRLTRFKMLLGSCGVALCFACLATAQSLPSSFPHLYAGAPSGDYSPEWQSYFEVIEPLPNVTFPLTRSFAGNLPVRRADHPNDTLFFWAFEHQNGSLTSNTSTEPWGIWLNGGPGSSSMAGMFFENGPMHINGDYSMSSNTEFSWDTVADYVWIDQPVGTGFSTADEAGYVSGEDQMGTDFLGFLSNLVKVFPSLATRPLYITGESYAGTYIPYILKAHFESPNPPVTIAKIAIGDGSVGSGPEFQDLPAVTVIETYPQLINYDPEVFEYFEEQSHLCGYDVNLTYPQNGTIPTLGYVPGIYDSDEAGSFSSRLKFSNNFKSRSFRSRLLSRFQERSKTEDLHPFAKSTHFRKREERRQDWIRSKRDLTGRANGTIDSRYGCDLLDEFIDYAINFTFPWTLSQPDGGVFDVYNIPDALDPEVPIDASVFLNDNRTRAAIHAPTSKDWVLDFDFPFGALGGPEPMTFLTDLATNGTEKGVGFVFFSGNDDSLIAHRGTEAPPSIPLQNTTFGGIQGFTRKPATPWTDDSGTLAGIVHQERNWTYVLFKGAGHLVAATAPANAKIFLQQFVFGTNTTGLVTGSTVTGGEDPELAEDVMPGSDPIFYGSLSTESSTIWPEATRAAWTSFIQTETASVTTTPISTSIAVSSTSGAVRRTVPCYMFTGLTMLLYVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDJ9</accession>
    <name>A0ABQ8VDJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microtubule associated protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_883648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007145">
        <property type="entry name" value="MAP65_Ase1_PRC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321:SF41">
        <property type="entry name" value="FASCETTO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321">
        <property type="entry name" value="PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03999">
        <property type="entry name" value="MAP65_ASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="645"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="771" mass="85633" checksum="DBED2F062BE2FFFB" modified="2025-10-08" version="1">MSSTSLLTTLLNNLHTHLQTQTELLPTLHAQLGLPPTALEDDLKKLQSTLMEGVETQIDSRRKEVERWLENCNEAEVECLKYAKALGGNTKATGSSIGELRKVQQLPKRFEMIGEHQEKLRQLYHTKLEQLTNITHRLNAMARSLSSDFYSQDILEPTSASEGGLDTNVHRDVTPERFSRLEKELARGKAEVTKRLNHLSDIFTQIDFLYNELGICSPSLEDLDSVPSSLYASSSQLHPPSDPFTVSISTPTPPPRHSKSYSPLLLSDDEEQQSDVAYQRIFATFVARVEEAETEGRSVLPTSSTPLGLNSVDPTPSLLAWAAALCSSLEDTKRRREAHIQAMYDQLEGLWWRLGVAKEDVDAFVDVNRGSTEECVQAYEEELERMLELKRERMGAFIGSAREEIQNLWDELMTGEEERGAFGPFVDDEHTEELLLIHEEEVRKLKEEKRIKAPFLASIKKYFDICEEEKELAIAASDQTRLLGRGARDPGRLLREEKMRKRVSKEKPRLEQDLLASIPMWEQETGRTFLIHGESILRILQELVSAADQENKRRPPRAGSVPPRATTPVNHAGHSYMPKGTVTPAVRPAPGGANSAPNKRMKYGDESASRSGQRAPLGAHRAGNTLASSLSQKPMDVSPAKIPGSRSSRLPSSLHSSTSLPRPIAMPMPKPGTQHHALGHGRVPTSGVFTYSGGNIGNGLFPKGIRSASSTLTGYTAGTRHTSGSRAAEKKASRAHRESFRPRPSMDGIDDHRLGKWAVNGFGGVKEEEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDR8</accession>
    <name>A0ABQ8VDR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="34871" checksum="97943504C6A9327C" modified="2025-10-08" version="1">MSLQSVASLPMAQDDPPSDEEWFTPSGKEGTLPSGRHCSSVEFSTPRDDGLHHLSPGPWGNVPREPMADALELSPSIRMRDFAEVVVRPVSAVPAHHRQQLTSHRGPFWDLSLASVSGHGLQPAPDIRAHKQRGRTSYSHHSRFRARTREPSPGPDFGAHLRRPSRSLSPVVRYPPAQFDAASLRASRDQGQHHLSSTASSSYPPSYGAATEQHVPVKNRHRFRDPRQGEISLTVPAAMLNQVHPLVISALRTGWPSFISLNYFSRRMSEVGKSLISSGMWIMLDKLSSSPNAYESFPSSRSRAVAGTASQRTCPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VED5</accession>
    <name>A0ABQ8VED5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_371762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25054" checksum="54533CF7DF119F3B" modified="2025-10-08" version="1">MSSNALFNRGLNHSTPFSRALFVLCRALDLPVEYAILLGGTSHRTILLAMALISFIKHTHWATRISQESMSPRAALFTGISHSFGNLLNTVLFVATSRDGDGLPVHTIIGMAIFILGILVEWGSEIQRLRFKKDVKNRGRVYTKGLFGLTRHINYTGYLLWRTGFALAAAGWVWTLVTCGLGAYKCLTSIIPELDEYCEKKYTNQWTKYKEDVPYKLFPFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEF9</accession>
    <name>A0ABQ8VEF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tubulin nucleotide-binding domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_960119</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the misato family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049942">
        <property type="entry name" value="DML1/Misato"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029209">
        <property type="entry name" value="DML1/Misato_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019605">
        <property type="entry name" value="Misato_II_tubulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391:SF0">
        <property type="entry name" value="PROTEIN MISATO HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10644">
        <property type="entry name" value="Misat_Tub_SegII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14881">
        <property type="entry name" value="Tubulin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Misato Segment II tubulin-like" evidence="5">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DML1/Misato tubulin" evidence="6">
        <location>
            <begin position="128"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4481324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="509" mass="57868" checksum="3BADB25F666EA9D6" modified="2025-10-08" version="1">MREILYVQAGNLANYIGTHFWNAQESYFTYSDHEETIFNHDVSFREGETPQGDPTYCPRLISFDRKANFGALSKTNAIYENGDIEDSQLWWGDVAEYEHVPIEPHAYQTHLLQSDRESTFSALDSVHGIRYWSDFNRVFYIPRTIQMLPDVPDWQQSEGDWALGQESFQRYNEETELMESSVRLFIEECNSFQGLQLMSDTSTFGSFSSSFLMAFHDEFSRAPCLSFPLMGDAVPRNVNVENAVPTRKIVNDAVYLRELDSLSLLTVPILNPKTWSQGYWDVNLKISDDHYHTSSILSAHIESATLPLRLKVNNEDISSISENLNFHGTHRFSQLAGIFPVAPGATPQDFLRQSFNFSILRNSSMATVNFARRDVTRGFSASNLQAYNSWYSQEVIKGPFVSSTHAQAYPLPSSFPDIFRDEGILANHRQTLHTERNPVLPSASLFTTLSANSRTAEMFADYAKVAQTCVDRRKIGILPGLVDSLDDIKELVNDLWTIHDSYSERSVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEP4</accession>
    <name>A0ABQ8VEP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_921260</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13980">
        <property type="entry name" value="STKc_Vps15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="28"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="507"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1202"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1548"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="939"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1001"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1099"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1001"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1015"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1049"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1099"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4486885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1666" mass="183669" checksum="C941AB148F59A684" modified="2025-10-08" version="1">MGNIQSGSTLTRTTVALDSFIAELGGEILYEKSLGSARFLKTVKCRHQNGYLVVKVFIKPDPGLSLRNYLRRLKIDRETLLDIVNVYNYQALVETEKAGYLIRQWVASNLYDRISTRPFLSAIEKKWIAFQILNGLRDARNRKVSHGDIKSENILVTSWNWVYLTDFASYKPTYLPLDDPSDFSFFFDTSGRRACYIAPERFYTAASNPEISAKKSTLAVEEGQRDGKVTEAMDCFSLGCVIAELFLEGAPLFTLSQLFKYREGEYNVESHLNLIEDEGVRNMIKQMISLDPLSRPTFDNLMQASRGTVFPESFFSFFHNYVSSNNEISGISPFAPNGTSIPNPGDQTPSFSATALRSGTLTSTPPAPGGSSLNVTFSGDVLPNDSDNRMERLWADFESVEPYLAADSAEESTMDVKIDFHSTTTSVSRPFQDILPIELQIPNRASKLNSILQPKARATLDGPALIILAIVTANIRNCYLPSSKVRALDVFLALSSHLTDEAKLDRMVPYIVDLLHDEAAIVRLAAIRTLVQVLMLVTVITPSNAAIFPEYIIPNAKYLVQDPEVSVRCTYAQCIVQLADTAVRYLEMGQALKAHGSFRISPEAQEYDQYEVSYEASLQDLQSSIQEQLSALLVDSSSIVKRAVLHHISYLCIFLGRQRTNDVLLSHMITYLNDRDWLLRHAFFESIVDVAACAGGRSLEEYILPLMIQALSDVEETVVAKVLASLTSLCGLGLFQKMRIWELMSATLGFLYHPNIWVRQGAAAFIAAAAKHLPPSDVWCILYPSLRHFLKSDVDTIDEKSLLNAMKPALPRQIFDATVQWARKTDRTNFWKAGRRGGGRTETPRESVASVRKISTSLSKNLSEEDEIQVIKLQQLGMTPAEEAKLMAMRDYILKLANALSSFSSRAGPDIGATKHLKVTGDVELPKLGVVPQTVFLKSSSSETSSRVSRSRRSDITGGTAMPGSPLSIRPFGDHMNFVGPPSSGAPFEDLRRRLATINGSASSLSLAPQTPTTPRSSLPSHLPQPSPALASGAMSPAPVERPGSPTESVVSTSNNSTSFRPLSRMQFGGNANGDGSHKAAPAVGSSKTNALGLLDTHSHLQTESSPERSGRTTPVSLSQTIRPVNRSRVPSLFPISTYDGQEAGINNLLENLYLDNNRDLQHDFGPRVHEGPVRRRNPVRHSLVSRDGIARKMDSVLVTHLGSHSDSITGLAVSPDQTFFVSASDDKTVKVWDTARLERNVTAKPRHTYSQHHARVKCICILEGVHCFASAADDGSLHIVRVHISQHTGTLPKYHKLQLVREHHVDTVGEYITAMQHYNTDTSSNLVYATTHSIITILDLRTMGVLQKMENPRHHGPITCLCIDRKRSWILVGTSTGVLTLWDRRFGLFLKSWHVGVASIGHLVRIHQCIVHPSKGRGKWVMVTVETSKSNNDRAFTILVEVWDIEKSLLVETFVVRRGPSDNDSIEPHGLIGVDADNSPAAAIAALVRSRQVGEDPVIHPQQLLAPAADVRAIVVGMEFGGHSAVHRSDLANFTGEAPPKYAGKGFMVTGSEDRKIRLWDLGKIERSTVLCGIDTDAERPSYSVSNNGSASTYIEGWSATGSSTQQNRPTQRISLITHNQQTLLRSHQDIITALVCIDSPFRGGIVSGDRAGVIKVWKVEASEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEY3</accession>
    <name>A0ABQ8VEY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_369298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="53745" checksum="61D0090BC8CA2232" modified="2025-10-08" version="1">MSPSTRRLSRSKILRRIPPRNRSFTLEPKLPPELFNLILDYLQFSLPTLKVCCLVARSWNARCQPYLFRVVNLDVWSLPPVALQIRKRPFIRRLEGLSRKSHLVQFTQRMWIETTSSRVGNKVTPKFLYQILTNIPMFTNLHTLVLNVPWNFRWGSSSEWPSKTLGSSLSNLIRQNPNLNSLSLSNPIFSSLDDLLAIVGFYSLNLEHLTIENVQSIPEEMRETTSDEFRLWMEEIVAHREPHHFHLSMLGLGFMHPRIRDEILMYPGFIDWKEVKHLNLSWDRHHASSCSTLLYCCFHDNLETLILSIVCYTDIFALDIQRNQLPKLKFLRIFSESVAAITTVLEQIIPASPRLLGQIEVVLDWAVPGVKKIHNSRTNSPVVSQLDPLLAHWMQIQYEYFRFVHVDIYMFYRKFSLKELQKLFQVLLPESFRIPGFHFGQCHGGFHYNNQCRGTTSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFD8</accession>
    <name>A0ABQ8VFD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_832266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="330" mass="36248" checksum="9AF21C95D7DCCE71" modified="2025-10-08" version="1">MNQRSCQSFTLIMSVPTIKLNNGVQIPAVGLGTWQSQPSEVVAAVAYALKEAGYRHIDCAWGYNNEKEVGEGIRQSGVPRSEVFITSKVWGTYHSRVEEALDETLANLGTDYLDLYLIHWPIALNPKGNHPAFPTLPNGLRDVVHSWKLSDTWKQMEALVQKGKVKTIGISNFSVKKIEEILPSAEIIPAVNQLELHPYNPQHELLAYCRSKGIVPQAYSPLGSTNSPLLKDDVVLKIAQKHTLQPSDVLLGWLVVHDIVALPKSVTPSRIASNLTGTITAIGKLDKGDIAELDGLAASGKQKRFIMPPWPVDLGFDNWTAPMPQPQPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFS2</accession>
    <name>A0ABQ8VFS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxalocrotonate tautomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_765018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028116">
        <property type="entry name" value="Cis-CaaD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14832">
        <property type="entry name" value="Tautomerase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase cis-CaaD-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="135" mass="15638" checksum="6B0A14B1634E7393" modified="2025-10-08" version="1">MPFHRFYCSPNLYTREEKQAIAQTITKYYAKLPPFLVLVSFIDVDKDSFYVGGEPNDRYLRINVQHSADPVQGYVVSRPWIEGYEKALEPFTKGKGIGWELQMTNDDVSFLPVQRKNPHSHFHCSLTSTLTPPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG18</accession>
    <name>A0ABQ8VG18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046521">
        <property type="entry name" value="DUF6698"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20414">
        <property type="entry name" value="DUF6698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="498" mass="56280" checksum="21D8B59B33E2D017" modified="2025-10-08" version="1">MAYKALLLENESVLPIMITVTATIPSPIRSSARHSSPIVDDHDTEVNDLRRQVLALTNAKKPSEDGKKRKRVPKGSEPTPLQQGRAIPRRVTVFDDLHTIQSQYDAYRRNGFHKPPNDDDDDIDELEEGPSEEERAEKRNMERGYTAIKEMEHVMPNFIKRVGEEGGQALILELERGADSAKTHDTQAATKIIGQELNRRVRRVNEARIKEHEEEIRRVQTETEAVLKEHAAQRENSSTDHSHDTVIPLPLPPLPAPPLVLLPEFDEGSRNNRGLENDMTGGLLCPGEIDWKDHITRTAVQRMDPEYDFASSAHSLCFYKDEKFDLDDPDNGFLQSHWLLQTYRTIFTSPSSAKGQSDDVENLPPSKKRTTSNSHRAHVANIIHMTEVTPRSIAYAAVHLHIALTDASHWTHSYNGYNYQDLWNFVVDFFEDPIDEEAEKQGKKLLKWWTDRIFTGTGSAANSRGTKMVSRRQVVVKKQTISSSPVSPLSPAPLLSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGC0</accession>
    <name>A0ABQ8VGC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_324494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050665">
        <property type="entry name" value="Cytochrome_P450_Monooxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24282">
        <property type="entry name" value="CYTOCHROME P450 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24282:SF211">
        <property type="entry name" value="CYTOCHROME P450-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4493291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="45788" checksum="AA32797B818A7D12" modified="2025-10-08" version="1">MRANIHTTPEDIINLLGHSESPSASVSELLKARSLANQRLRHTFNLTNTFVKAETDIHNTFVGRMKDLIRAQRRRGQWGEFLHVARQAFACELNSYVPTEARFPTAFPDFIQVLTLRIIVVALLDPDRDMESIDAEDLRVSATLITKLWGISKLKKISSAVPLMNASCTSPDIDDLTTLNYHLRRLLPDTEKYPNPINFVIPTWETLWRVVATCLAHVHENVEFRRVFEELLEDPTSERFKTTSFDSKLCADWIISETLRLHPPSRHISRSFVIEQPPFLQFVRALLPRSVTDQLGLAPLIRSEIADVEGIHLSVGIWGADVLEFSPRRWGRYTNPSETPTLFAFGYGPLICIGKNWAPMAAALIVGAILEGIEREELEIVGTGIIGGRAGWLGWRVQSREAFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGD8</accession>
    <name>A0ABQ8VGD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_866968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="356" mass="39387" checksum="7A6BCB26302AC38F" modified="2025-10-08" version="1">MTPEESDLLSHIGTLIYYGIVVLIVDCFYLLAEFITLYLFIQRIQKILFICSLTTMATATWDFVNQCALNLIQIKVSLMEPLEAGLQAQVDAAHSAVLPWYSMMVWPISINIVIGNGIVLWRTWAVWENDRLIESALLMMMLVNTGICCSDAIVGTIVRSQGVKSGNSSLETAQMFICLAINFIATGLIGVKAKKRPQLVKEYFSLSRKRREIVERTVLVLTESGVVLLLFQLNISAAQFSGINIAWSIIATMFNAVTVLYAVVVIIMVIVDRSALDKLFELNTTINISVSEKNGQTTKISTLRFAEGGHQATYSTGLGSADLEVIQEASSRIDRLASSNGDIKDRSRNESEITVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGQ2</accession>
    <name>A0ABQ8VGQ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053221">
        <property type="entry name" value="Burnettramic_acid_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887">
        <property type="entry name" value="CHROMOSOME 21, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="55384" checksum="91BFC0EC47707CCA" modified="2025-10-08" version="1">MASSQHTSPNSPSTSSSRPSPVTASSTGVQLVHDADFLIQTYIPAPSDTETPPYRRDDIPQLLPLCIPRISVSANPASAFARGYNPALDTVGITQEMFLSFIDGLNLAIVASPPLRIVNVVGQLVGFVPNHWTQLASIIVTTSAQVGMRVLSKTLTDRYLRAANLNVFKPRGLSVRLCTTPAMLRLVAPPGSHTTDDESKTRATINKIGRGVGTIFLKVPLPIIGPIAARVIHSLADKPPPIAPTGYPGDPVNAPVLMRRLALLEHTFPGATLPVVTQGLPPPAKANGVMEMINSWGLKFDEKRENKAERKNEERRRAWAQIQAAGVANGGYPYGGGYQAIPRNRSPSPGPVAMPTPMIGGAAMGMSYGGSNVGYMDYRDARRAGRRAAKAERKAYRRMQKGQRKGLLSGMSRAERRATAADLLEHWATNRVLWVVVMPAEKDEAIADIQIAEDLANEEQVDEETWKMAMRLEKDQMEDEIESEEEWEEELANETQHASTSHLSPPKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHE9</accession>
    <name>A0ABQ8VHE9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Maintenance of mitochondrial morphology protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MMM1</name>
        <name evidence="11" type="ORF">C8R41DRAFT_980857</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MMM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21671">
        <property type="entry name" value="SMP_Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03103">
        <property type="entry name" value="Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027537">
        <property type="entry name" value="Mmm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="38"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="10">
        <location>
            <begin position="77"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4494370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="297" mass="32818" checksum="D82A6C7FE675FFA8" modified="2025-10-08" version="1">MGANYVFSLQPTFTQGLIFGQLSILVLLVFVLKYLFMDSTKYPFETTSYHPRINSDSIMRSQKPYNQASGESELSKADESAEWLNSLLHQIVGTYRSKLRNDLPGPGGDEVARKRVEDYANKIRPASFLDKIVVHSVDLGSSAPHLCNGRRVHPSPSSNPQEIEFDVNYVDSVSISLSTSYLFNYPMPLFARLPVALTISLSLFKSSVTITPPIHTSPAPTLTFSISPTFTLDLTTMSLMGSRAKLANVPKLHDLIQHQVHRVLATKGVWKVVLPGLATVDEVKQEVKNELADAAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHP3</accession>
    <name>A0ABQ8VHP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UV-endonuclease UvdE-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_829078</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004601">
        <property type="entry name" value="UvdE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00629">
        <property type="entry name" value="uvde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290:SF5">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03851">
        <property type="entry name" value="UvdE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0228">DNA excision</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="479"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="535" mass="60497" checksum="54723B4B97BA6FF6" modified="2025-10-08" version="1">MYFSWLSLSRRRLPSLYSKFPYLQRPWSSTLSMNSLQETPSAASSQRRSARLRTIVNNGTSVVTAAPVANDIRQKRKRVSDKVSVEIEDAGLSSELSAIEDEFIPKAPKKKRKKKAGKEASEVVKVDADEEPYDEVEVKKARRPRKPKPEPVYIIQDVERRETKFRGRLGYACLNTILRNKKPASDAVFCSRTCRIDSIKKNGMDWVKELGRKNVQDLITMIQWNEDNNIRFLRLSSEMFPFASHPIYGYSLDYCSSLLAEAGALAKKYGHRLTTHPGQFTQLGSPKPGVIESSIRELEYHCQMLDLMGVGKDGVTIVHGGGVYDDKPGTIERIKTTIRDVLPQHVRDRLVLENDELCYNADDLLPICEELDVPLVFDYHHDALKPSSIPPAAIIKRTNAIFARRGIRPKQHLSDPRPGAVTLMERRAHADRCERLPDELDLEGIGIDVDLMIEAKDKEQAVLQLYRIYGLEEVKYESLRPPNENQTKETKGRKSNKKAKKGEQAMIDGVEGEGEDLVNVDEDNVEDGVGDMVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHT6</accession>
    <name>A0ABQ8VHT6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DASH complex subunit DAD3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Outer kinetochore protein DAD3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_833296</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013965">
        <property type="entry name" value="DASH_Dad3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28017">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28017:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08656">
        <property type="entry name" value="DASH_Dad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4491819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="106" mass="11939" checksum="B76F77F36F671A54" modified="2025-10-08" version="1">MASPPPSGTIFEQNPYENHPSLSAVEAEVLWEYAKLAQNVKLVTTKTRKLMDEPDQMLVARLRSLETKMGLVMVLFKASVWNVINEQPVDVQYGSAETSEDTTIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHY4</accession>
    <name>A0ABQ8VHY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_726409</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="112" mass="12464" checksum="F5E2D38CD9D0E804" modified="2025-10-08" version="1" fragment="single">LGLIFLHQSGIVHQDIKPANIMISSDGHIVIADFGASNALPFSFNYDFPVMPGSRVQKTFHPIVLNAHDFITFTPLYAAPELVCRNRAGLIIYDSRVDWWSFGVVLYELATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI13</accession>
    <name>A0ABQ8VI13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_724214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4495280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="73" mass="8236" checksum="F906E57CEC04745E" modified="2025-10-08" version="1" fragment="single">QIRSRITVCKRLKLKCDRRNPCGSCQKRDTVSRCIYSPAAAEKVDLHSLNNRLIQVEATLAQLTSGQFTPSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI19</accession>
    <name>A0ABQ8VI19_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_828542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="53908" checksum="42027F83FF778FD6" modified="2025-10-08" version="1">MSMSSSRSSSAFHYSAHLPASKSPAQYLPFDVLNEIFKYLPDLQLVKELEAEVISPKTGPYILRPEKYPWSLSRVCSAWRAAAIYEPRLWSRVHLEVGPRQPSQGKVQLLQLYLSRSRNSNLSVSLHCTWTGRARDNALLTMLFTTIGRWQSLSLHALAISLPLFNALGPFPMLESLHLYVAHQAKTPPLANVHHIFRHAPRLHTIRHRHSDDRSVFMMPLDQLKVYQGPTSSIPPESGCQWLSNLQWCALAVNGQQPGWDSMEVNAPHMREFSIQERVHAYNTTAILDILTLPVLEVLRVKSAGRDRLCDSITGLLDRSMCILTELCLDIPDLIAPIMDAILILTPQLVKLRITSKRLVPDFVESWIYDPKTHADNPCILQHLEQLDLGRSTFTPSAEIALLQMVRSRWEIPEKMTVEKYFGGPAVHSIVRLRSIQVPYKFQRTKRSQKKILRVWKEEGLDIQFGPGSQNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI87</accession>
    <name>A0ABQ8VI87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_308397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="247" mass="27929" checksum="B01639FF7F467D7E" modified="2025-10-08" version="1">MSTSRLSPMNPSPQHNSPTVYQSSTDTFRSLLKDGTLKLFTNPTILSGRNDEGVFDKTLEGISFGPEIEGASNNYGLWEISDYQEKPKHNLLAKFFKEPGPQHFGEVKALRMMGLLVASGMIRDPHPDGRPLLRPAIIMEKKEGVLLRNTAVYKLATLQEQRSMTEQINAMMCRQAVEDAVTFKVYHYDNNLSNALLTFLDKEPAKVIDFIKSVKGLELVDYGDAYMVMKDVSKERLYDACMNRKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIX8</accession>
    <name>A0ABQ8VIX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_827281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="58"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="318" mass="35246" checksum="58631CF6EF9869C9" modified="2025-10-08" version="1">MQSEILEAVEQNGTTWAPAVAEAFRQIYGRRHQVLNPTKYHAVVKENISYGPHERNVLDVYSPTEASIAPRPVIVYVHGGNLVAGDKVWYKGSLYANVGNYFASHGIVAVIINYRLVPNVAYPGGGDDIQMAREWVYHNISKQQSGNGDPEKVVLVGSSVGGLHIATNVYLADHSNVNYKPVFPPIAGIVYLSTPFSFDTTPEDRQTALRAYYETEDAKEIYEHSPVGLIEALSASSLVLDPRKFPCLIVLAQYDPKEIQDSTFSFIEEYRRKSPQGILPEFVVVAGHNHISHVCSIGTEDDVLGRILREFVGKVCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJN7</accession>
    <name>A0ABQ8VJN7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_826238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046261057" evidence="3">
        <location>
            <begin position="26"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="228"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4496588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="33522" checksum="AA793376FA2A3F25" modified="2025-10-08" version="1">MRRHFSHGLSVVGVFLLITLPRVTASPLTIRAAGPSAANNIDPTASSEIPPLPDEIWPVEFFQSKDNSLAIVIDRFYGFKAQHEDGKVIEFRYPETNGVPLMDFGYSMHPWTGHDFDNWYQAHGMIIMFDSPHNGFDFPTKILSRLVFDDDGRIDGRVDGTPCLIKFRQDARKKLNEWIKEATKGKGKETEVMGEEEVKRDKEREENRRKGEQEGRSRIIQANITRKKRLLENSVRDAKDAVRQAEEDIRNNRDALTAIQRKRRLKQLKKELKQKEKTLENCRKGLSCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKI2</accession>
    <name>A0ABQ8VKI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA binding HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_918181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="34466" checksum="B1A324ECDA0245DB" modified="2025-10-08" version="1">MRQLLKFLFLPLSLIYALLSVFTFAPTITHSTNSSITLPNTDVLLNALRAHYEQFQVLLTQVYTHQTDTYLLQLLGEDLNEFGRTVKQYTNIFEPQELQILQNGVQLMVIDVRALHEQMMESSHQGRPEVIHHQHTGHRGRPRIEIDRDFLQWAYTQRTTSALAHFLGINRDTIRQRLLEYGIASPGQNPFPSASRTTSPNTLGLSEDDILDAQIPDPSHLPEHIRLEAASIPSTLGYLSHMSDEQLDSLLSSLRVYYSRAGIRMLDGMLRRLGHIIPICKTWVMFASSWEHFPAFPSIPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLY2</accession>
    <name>A0ABQ8VLY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_917443</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF21">
        <property type="entry name" value="NON-REDUCING POLYKETIDE SYNTHASE AUSA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="397"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="1283"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1662"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1776"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1283"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1453"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1634"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1634"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="1331"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2128" mass="232429" checksum="FCB5E09D70E6CD7D" modified="2025-10-08" version="1">MSPLSRQRLLVPIFAGQGSTPSTHSSYINSTIRRSQHGLCATLLTICHEAFIDELSSLSAQELTQAGVDPNDFRSPETLLTMWMSRFPHNALISSSALVLMQLLQYLSFVEQFGAENGSLRPFADLLIGHSTSSVGILGFSSGIVSACVVASSNSAKSYLSFALEAYRLALWIGIRCQLYCFGTSDADTVLPWSVVFIRISTEEAQEAISDFESRRNSSESEDPSKLYITAVMDDHCVTVSGCPPILAEFTASVCRTLPSVLAHQTTVDTLYHSPVHLRKVRDQVLVDVADRNIRFPELSHLHALVRSTSTGVLLSPSVESDRPLVQMVVDMLIIEPVRWDLVTDQVSRSIPEAEVVVLNNFGPGIGVARTLEKICSPGRVQLRDLCSEFHETRSQQEPIAIVGMAVNMPGSSNISKLWEVLEKGLNTLDEIPEHRFSIRDYEGTKNPNRQMKARTGNFIQGADEFDNRFFKISPREAKSMDPQQRVLLHTAYKALEDSGYVPGTTSSSQADTFGCYIGAATHDYVQNLRGDIDVYYSTGTLCSYLSGRISYTMGWSGPSMVVDTACSSSLAAVYQGARALMNGDCKSALVGGVNVITSPDMFLGLDRGHFLSPTGQCRAFDAAADGYSRGEGCGLFVLKRLSDALAENDNIYGTIRGIEVNQSGLAHSITHPHAPTQVALFERVLRNAAIHPSRVNVVEAHGTGTQAGDINEIASIRQVFAANRTVQNPLHVTSIKGNIGHLEAASGAAGLAKLLLMLKHQTIPPQISFDKLNPSIEPLENDNTKILRRSSPWKPSYNGSSRMAFLNNFGASGSNVALVLEEHIHNPSQAFDHPLVFVLSAKDEHALHKLRFDYIQWLQSPESKALPLVDIAYTMTARRQLYSYRLAVVVSERTRLVESLHKAAIVSSSAQPPRRVVFVFSGQSSEYPGMGQDSYSTSPLFKHHVDECHAILISLGFHGVLSIFTGNEDVLSDSEKIEAYQAAIFTLEYALGKLWMFWGIIPTAVIGHSLGEYTALVFAGVLTLRGALTLIAHRVRLMSRKCDLDLTGMLAINLSPDLVKHLLGTSENVFPLTVSCYNGPNDCVVSGPLKALEDFKSFLDATKGCRSKMLAVPYGYHSDFMLTISSELTSIAKGIEIRAPNLPVASNVDGNVVLPGEEGIFKPDYFARHCSQPVQFDGAVRALTDAFELSGDVWLEIGPHPTCLPMLKGHSSLSSNALLISSFKRNQDSWLTLGSALCSLLAADIPIQWRNTFSHLPHTRCISLPSYPFATSKYWAPYEEDRLVVSSRQPSLTSGYTFLHNWEQYPSSENGHVAIFETPISQLSDLILGHKVGGLPLCPASIFIELVLSAVELSIRRRDVSSNESLVQITSSRFLKGLVFKENIPRILVIEITLGDGQGSFAISSRVEPSNELILHVRGDYLLQSISDCAAKLCQMLPSVTGCINRLKDPSTRAEVFLSRTTYEVVFPRVVHYAKEYHTIKSLFVSPTDLQGCASICLPSGHYRGTFTAHPVFLDTLLQVPGFIANLQGKRQPAESSDANLGIHVGDVFICSEITSCSISTTSLDDNATYSIYCAGVWLDNRTLSFDVYAVKDGDSLQIIASVKGVVFRQMALETLRKALSLAAMLGQPQGSQSLPALSNPPLQSRARSHSSPPNFVNVVGELHSRIFDAIAETCGVTREQITASSALDSLGIDSLMLIELSTKLQSLSSKIDLELQSLYSCKTVADIIRKSCSVLGLGNAPVLTIAPPSLTCVESEPSSPSTLVADDRLSDTVFSRADVYLDVRNVINAALGTTEAFGDETDLEAVGLDSLASIEILHALQTHYGRQVPNDFLRKYRTISAIQEYLGSSKFDLPHRRLFIPQSPPKEAVQARLIGILRLGTNPVRVQDCNKMNTPIFFIHDGSGLVNYYDKVESLHRDVWAIYNPKFLFALPWGSLKDMALAYADYISALSTGPILLGGWSFGGVVAYEVALQLAKRGVTTKGIILIDAPNPIGHVPLSDALIKTIARYDRKNGPVEIGKLVRTQFAMNAQLLSAYDPHETGGVCPPLVFLRSELGYAAEGIQVADIPSWLVDRSDPSTTIAGWSELSSSVKVWDVPGHHFQAFDNANIASVSAKLLQACEYLETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMI2</accession>
    <name>A0ABQ8VMI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_211860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047166542" evidence="1">
        <location>
            <begin position="23"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="207" mass="22627" checksum="53C4855229F1FDA2" modified="2025-10-08" version="1">MRFDVPYLVFGMLACISIHVQAAPFSGVANDGLGLVVRDSLTNPKTHLRVRALSSEQSRSGSWNYVSPSGYGDHWNVVMGSGDNNMILVRFDGSHGTALTRQGNLFAHLNPPYHPIEDRVREAIRHLDPLNSRQVVFMNQYKFHGASKNLSPEKIVSEITAAGIQHLEHGGIISIDQKGVPTITVKVQADGKVVSCNIRVMDGKVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMQ5</accession>
    <name>A0ABQ8VMQ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal RNA-processing protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_759123</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22525">
        <property type="entry name" value="KH-I_Rrp4_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Exosome complex component N-terminal" evidence="5">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="RRP4 S1" evidence="7">
        <location>
            <begin position="65"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="6">
        <location>
            <begin position="159"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32073" checksum="2CAC93AA0E23D423" modified="2025-10-08" version="1">MDEDDEDFLETGGMKLTWPGESLTSSQDYMRGHGTYVDKEEVVASVSGLVERVNKLITVRAVRTRYNPEVGDLVVGRITEVQPRRWKVDGNSRQDAVLMLSSVNLPGGVQRRKLESDELQMRTFFEEGDLLVAEVQAFFGDGTMSLHTRSLSYGKLRNGQLVTVPPILVRRLKSHFISLPCGVDLILGLNGYIWVSKHVKENEREGEEAFDAEAVYSNQNDDIDDSTRMAISRVTNLIIILASRSIPLTDTILLDAYDWSLEQEGDVKDLLHEDASDALVTTILAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMZ5</accession>
    <name>A0ABQ8VMZ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease for cytosine/purines, uracil, thiamine, allantoin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_758811</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="518" mass="57370" checksum="7774FFCE1DA399FE" modified="2025-10-08" version="1" fragment="single">LAPTPPEERKWTYWTFAAFWTAHASDATAWTAGSATVALGLTWWQAWLALNVAHMIGTILIVANGRMASRYHVGFPVCARVSWGMWGSYMAVAMRAVICIIWNGVNTFYAGRLVDVCLQCIWPSWALVANTLPESAGITTRELTGSLESPDLVQCLTFIHPRDLKWFYVAKSVIVLTAMHGILAWWMRKNGGVHFPSQNSTQLSGTTRAWLWMQAFNSGFGAVSSLTVNQADIARYAKSPNDQLWGQIFVFPLASALPGLFGVLVASASQEMYGAPLWNLWDVTQKMLDQYPQNSGARFGIFLAAGSIALALIGVNLATNCLPFGSDVSALFPKYMNIQRGQFLCCLLGLAIAPWKILQNGTTFLAFLAGYGYWLAPVAAIIFVDYFFIQHGNIVIAELYNGRPGGLYWYKRGWNIRAPIITMLALIPCLPGFAWTISDHVNISLNAARLSTLSFILTYAIAASMYWTSYRIWPKTSTSNEQFEFIANVVDGEEASIELEDIEKPLSDKLSIRECPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNA2</accession>
    <name>A0ABQ8VNA2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein HRI1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_758251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.320">
        <property type="entry name" value="Protein HRI1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031818">
        <property type="entry name" value="Hri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043047">
        <property type="entry name" value="Hri1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16815">
        <property type="entry name" value="HRI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23554" checksum="BF015BD6C44A832F" modified="2025-10-08" version="1">MPATVSFRKSIRWIPDQASEPSDTVVLTGGKTGVFLDVRFLKDSNEIEWAFAGYRSTESEELTKFTHLIDSRTEDPLQVVDYGSNTVLSDGTILEKGEMMNPETGSLTAYEEVWQDESSDSNQAIFLQNVKYTSWYARVGHWQLALGRDSAGVFWAFQAHSIDGDWMVVHNLGVTNSGTVTLLPEDTSHWAEGKVLEWNGDRWLVLEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNZ3</accession>
    <name>A0ABQ8VNZ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Protein transport protein BOS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_757789</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">SNARE required for protein transport between the ER and the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 11">Belongs to the BOS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15863">
        <property type="entry name" value="SNARE_GS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF1">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR028865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4498099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27939" checksum="96DAAC3389B08A59" modified="2025-10-08" version="1">MNSLYTSGVRQTNSILTDLERLRSGDNSASLLGQISASLAAMHRTIDDYDSMAKREMIKAKQEKAQMRVQKFRTDYTEMRNQFERLKAEVTAEKEAAQRVELITSASLASPSANARQRFQTTYSQNNTLHPELVSESPFRGPSPQPGLSLRDQHALNEHSFIQQTESRLDEFLLQGREVLDNLRDQRSILKGTQRRLLDTANTLGLSRNVIGWIEKRSTQDMYIFFGGAILTFFCFFMIWKYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR49</accession>
    <name>A0ABQ8VR49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_916650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="153" mass="17202" checksum="DF0C8422504D1645" modified="2025-10-08" version="1">MATKEQKIWEKLHMIIEDDAANHRGAEDAGLLSTVARLEKGEKKLAALVNQVSHKMEALTNDDKLCGHEQEGEKDFILNAALLTEVTRALEMQSALPDDLLDNDILDLKWLAEVIQSILNDDTESNRLEFLRRLQAASARTLSHALEWLADVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRL0</accession>
    <name>A0ABQ8VRL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_722896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="15338" checksum="64218D323A16AD2A" modified="2025-10-08" version="1" fragment="single">LVTAKENIDISPGKYGNVLQAASSEGHEAAVKLLLETGADVNAHKGYYRNAFQAAACGENEAIVKLLLENGADINAQRGIYSNALRAAARRKNEAIVKLLLENSADVNAQGGQYGHALQTAAYRENEAIFKLLLENGADINAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRQ9</accession>
    <name>A0ABQ8VRQ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4498991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="350" mass="39452" checksum="BC647444A13BC159" modified="2025-10-08" version="1">MTPLTYNPASAHSPVFISSRSCSPQPINSFRHRSVPLRPTTPPSFSESEPIFPPLAPTSGKQSHSSKLIPKPPGEVGRPGRGGYNLRKITNWSKKDYDDVKDYVKLLVTRLDCNVPLGQQPLVNIRSIRDEAIAKFDFLAQYDNAWVVDDFVHCQLHYQKRLVRNRKRKMASSTYNAASVCSPGSISSGSCSPLPINYSHLRSVPFRPMTPPTCPESEHLFPPLALASGSPPPLSAARQLLHSWKSIPKPPGEVGRPGRGGYNLRKIINWSKEDYDDVKDYVKLLVGRLNCDVPFGQQPLVDIYSIRDEAVAKFEFLAQYDNTWVVDDLVRCRLQYQKRVAMNRKQRQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRS1</accession>
    <name>A0ABQ8VRS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="204" mass="22629" checksum="F8AF86F8D44A40B4" modified="2025-10-08" version="1">MPTFYNDKSQVIVSALNTLDQKPPPSLREILSAYRSKGDGDRDMLLAMLNAKTAEDRRIAETSALHRTIIETCSHEISSPSLPPLVYPNLSQHSYQARSSTLSSGLSHDDRESHMSKSRSSRSPPHHHTYSPYNRPVSRDSPTPPLQMPPSPYSSASNPDSNSSPKLKERGTMPISSMLLGQKSLPRTQPSQDTSDDGRLHKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS28</accession>
    <name>A0ABQ8VS28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_88082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="28364" checksum="45A977E8FEA2A125" modified="2025-10-08" version="1">MASYSTSYPHHHHSTSYAGPPPPIVPSTSPSISSSSPSQSPVQDFREPEYESFSSTGGNFPYLTSQMSLGSASASAPYLPLSSLNSLNTDALSGPGRRPTPTRLSSRTSHPRLNDLNAYPSSSNGAMQGMRHGGGRSPNPRSPFRPSPLSGPASATSPGSYFPLVPSNGGDISQLHNMSMEQQHRQQQAQRQQLRSPSSQSQSSTSLPGTPFDEGVPDGYLTATNGNGYFSHQQQRQRVPSVPSMGHGAMQNGYASFSAEGSVGYFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSM7</accession>
    <name>A0ABQ8VSM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_864141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047205972" description="Thaumatin-like protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="18093" checksum="E212B09B659B8287" modified="2025-10-08" version="1">MMKLSLLLSALASASTLVSAQHAFTLANHCGSSITPIVANTACGYSPRCSGAGYYTAAQPGVLGAGASETITIPVDWVGRIFAQNGACGASGEDCTITEFNLDTGDFYTPQAYDISNIQGFTQSIEIAAAGCDTVTCTNVNCGCTEAYPPGDESGCGDDSPVRACGAGNIAFTITFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSW9</accession>
    <name>A0ABQ8VSW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_815836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="59"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="192" mass="21870" checksum="83025E7CCBF272CC" modified="2025-10-08" version="1">MKAHKNVVEPSHWPKYLRYTQSYIYHSSVSLEVKKTINEGPKSPQRSSSSQNHNSQKNNHVVIRHITEPSHPAYNQFGLFASKKIPAKAHILDYIGEIHADERLTSDYDLSLLRLKNGESIGIDASTTGNEARFINDYRGIKLKPNAAFIDYRTDSGELKMGIWAANEDIKKGDELLVSYGKAWWKARTELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTV0</accession>
    <name>A0ABQ8VTV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_753424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="369" mass="42747" checksum="56EF4CA4E1CBDDF1" modified="2025-10-08" version="1">MVAHLRPDGPAPPNLELILPNETWWVEHFDYLKEHGYVMRPRYRPGWKPSYKLGTHEFLEREDGQALDVNPIMDAIRSSDSLMVAIKRVKTSSSEVEVGTLFSNDEHESNPSNHCIRILEVLSVPETADEVLLVMPWLREVDSPSFRTIGEILQFTKEMIEGLQYMHKSNVAHRDCSINNMAMDAKTMYPHQYHPRAPERRYDWTGRVHHRSRTHRPPRYYLIDFGFSQKYDPSQPRPLEYAIKSGGYLPPEGAAVIPCDPFATDVFLLGNMIRTSFLDVIDGLEFLRPLVNDMIVDDPFKRPNMDEVASRFSIIMKTVPSWELRSRAVRKNEFPLLKPFRAIHHLLWTTSMMFLLKPAIPTPTKSPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUF6</accession>
    <name>A0ABQ8VUF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_894272</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21742">
        <property type="entry name" value="MobB_NDR_LATS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05573">
        <property type="entry name" value="STKc_ROCK_NDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059233">
        <property type="entry name" value="MobB_NdrA/B/Cbk1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF400">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="368"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="720"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="735"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4498205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="847" mass="96059" checksum="73AE19B12C970247" modified="2025-10-08" version="1">MAASSSRRPLPVPPMANFRSNLADSRFEMYPHSSNFPYDYPQYQYDESRTAGFPVGTLLHKGFYDLLSMIPTPSPSRMLQQWRPDNSHSLVAGTRYEELDKGPIKSLSPPSPVLKKGRRISKDMVSHPTGFVHLVHASDADQAEALLTRWGPDGLGKLGDPRWANPIKNRIRQGNQAQVVNQDVNIPQQSYRESIGPIDAGALGPLRVVNGMSTTTVTSSSMLTTVARENFSTQPNIAVDGLPGRPGNSTIRWGRGLITHPELQEHDELGGPSDDPGKALPEVPPPRPIVPSLATLEKAVSARIYFENLYFPLFRHIPSREQRRLAMERDMMEMNLSQIQKENLRQRWRRNETEYLRERRRKVDVTTFTKLKTIGHGAFGVVSLVKEQSTGQLFAMKQLRKTDMLRKGQEGHVRAERDLLKSASLVSSPGGAEWIVKLHYSFQDRDNLYLVLEYMGGGDLLNLLIERDVFEEDFTRFYVAEMILAIESCHKHGFIHRDIKPDNFLFDPNGHIKLSDFGLATDLHWAHDTSYYEQQRLHLLHKHGIDLEDTNGIADGKKTKRMDRKEVERLMGGDGPEGVFTWREKNRRKVNLSVVVFPCGTNSYMSPEVIRGHGYSYSCDWWSLGVIMFECLYGQMILNWKQYLRFPKRLPNTKEPVNLSSEAIDLMQQLLCEPEDRLGSQASSSVSRPNSLIVQSRLSFVPQHSAADGSHLIKTHPWFRGIDWANIHRYEAPYRPELQNPEDTRHFDDDIPAEPLAPANGAPPDATRDPLLRDKVHGAEILDVRKALAFAGFTHKSPRVFSYVRAERAFDHLSDDVDVDSQATVRARGRSARREIQDVGRGRAISM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUN1</accession>
    <name>A0ABQ8VUN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="553" mass="60334" checksum="DC2282FFBC6E0661" modified="2025-10-08" version="1">MHNDNFASQASDTPIVHANPDPSDRVDGQLDPQEFSFGDRASYGHGAYQDVEYEEGSTDGNYPIFTKEEGHMESTGSGKEGVQDGKMAPYYYPRSHHVDIPGPVLTIASFSAGNPIPLQHPDHFPSSKDCTMALPDSDYYLGYAGVPSIILTMNSFSNDDTVPPQQPNHTPFDKAGAQDTGMPSDPSYYPGYADVPSPVVIVDTFSNGNIDPLPQPNYSQDYSQEQSMNTMPRLNGQPSLPVELARTSQGVHSSDNNLDNDIDTLQHVCTESSSYNNDPTPVNQSIQEKAMQKQEPADINVAMNVPLKDKADKAEADEDEKQGKQTPLQIEEEDTEDLGFPTLPPQFCNENISDPQADVPNSHIYPCDAASRSSIANHITVYEGEHGFNNTPMHDVTCDAFFDMLSSPPPSPDAPVVDHPHQPDVGEDSSVLLEGGFDHHGHDVTKDPGVDNNYQGFIDHHCAFCNHDAVNHPGSGAPSDLNQESQDSPHHTGLHGTDAGNEQGVSEDHHHPYQVNTIDKMQIDDGLYKSVNDNTGPEDFETPNPHVNTTLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVY0</accession>
    <name>A0ABQ8VVY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_607253</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="403"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="404"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="557" mass="63343" checksum="880D944A09C691E5" modified="2025-10-08" version="1">MKTWSLFTSIIRRLDDYQRIRPEEYSYELHPTNDEEDYSLPSPSHRRRKSVLHKRRFSLTIFSVVSFVQHALTLRRLVFIISATLFLLVVGILSSGVPSTYQDVRVYERSLPQHRIREAVNEKIGRDGVTERIHRRKYLWFDGALWGHGLNNVLQESFVMAYVAQQSHRSYVFEDHVWSQSPLPYTLYDFALRPSRIPMNAFISGPSAGGPVPDGSITHRAVSLEFFNTVCRSEERIMVNTKEAPIDASLGKDANEIVSWFLDELKKVEDEPCVVIDSAGRTLFDRELFGTKRILPIFSSLLESPILANFAWSPLVLSVVARNFAILQPDDLNDLYPSPPSYSHSNAGVLSGLVAVHLRRGDYSRHCHRLVGWDDEYMGVNQYDELPDRFDADAYLREHKFHSSVPTAHSPPSSTVLSSRNSTLSASPTTSRTSEDHTILTPYYLTHCLPEIPEIVARLHQVRLDNPGLKRIYLLSNGWGWWLNSLRDSLKKDGWEDVRHGGELETDQAQKHVAMAVDMAIAEKAEVFVGNGFSSLSGNIVTLRLSKGFKAESNRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW74</accession>
    <name>A0ABQ8VW74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Metallo-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_704378</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="147"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="40907" checksum="5967B30EAA9F14A2" modified="2025-10-08" version="1" fragment="single">ISGPALVALSSLTASDILWIKSLPKAELHAHLNGCVPIEVLYEIAGLSLNYISSDPPTGTETSNNSVPTHTEILSGLETLSNFALDDIHEFFGAFRTVYALISTRETLGAATRAVLQRFLDAPNKRNGNNIGGLEGGLTPDDYPECTYLELRTTPRRTPTLSPREYLETVLDEVEKYPRDRAALIVSLDRRMGVRTELGAGEGRITIEDTIDLATLLKHSGRRVVGVDLCGDPLAGDMSLLEPFIAKAKSAGLRVTLHIAETPGNSAADTLQLLSYAPNRLGHATFLDEQARELVLKDRMLIEVCLSSNIICKTVPNLSSHHISHYLDRGHPIAVCTDDTLPFRTSLTAEYALLLAPPPLGLGLTREQVQKVAEGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWR3</accession>
    <name>A0ABQ8VWR3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_717523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42052:SF1">
        <property type="entry name" value="ABM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11200" checksum="0318264C0B12DD43" modified="2025-10-08" version="1" fragment="single">MPVTEFATLEVLDSSNPSLITQPLLIDHLRLVAEKQSAVSGYPVLFFESLSPDSKSIFYLISGWSSVAAHYEWIHSQTNQELLVLLKDFVGVKGLAHVNVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXY1</accession>
    <name>A0ABQ8VXY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23073" checksum="AB0F466B422553DA" modified="2025-10-08" version="1">MFHSESSLLTATSHPLLRGPSHPTYLDAPDNEYYRSTASSICSDSSHFPQSDSEDSDYQNTSTKDLQKIIATVSETQIRATMLKLAGHSTQFRDAIARELKLKSSQSATKPSRRSRRFRRSTGSNTSCPPILTCSNCGQGFDGGDIRDTCHYHPGQLEDEIFEFMSQTPEGRIFKVLKTVSMWSCCEEEPGSVGCVNAPVHVELNEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY49</accession>
    <name>A0ABQ8VY49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_806837</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="883"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="929"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1020"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1112"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="268"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="618"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="889"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1213"/>
            <end position="1444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1448" mass="159936" checksum="646B9128C2A19D00" modified="2025-10-08" version="1">MSKFCAQDSAFGPQSQCRSFDFTLMFENAILSIVPSAIALALFVSYIRLSVSRKIIGVSVRRPDVLIAFILNLALNILTLIAWTIAKPTDVPVLAGSYLTAALVLSLVVSILNVILVSNELSRKDSSFATSLYLLIVLLLDASRLRTFSSAGKSSISMFFFVAFAASFAVRGLCLVLMNTPEPKESGVYKSSGFFSSIFLLWLLPLMWKGRKGTLNLDDLPDFDQRSTALYMRFETSWRREKRKTHPKLLKALLRAFLSTFMSPVIPAILMSLTQVVQPAMVNAAIQFVDSYSSDSPEPVEWGWSLAGMFAFIFLTLTCASTLYWYCIARTSAYIRGTMSEAVYRKTLALNVTCLASVPGGNPMNLISADIDRITSVIDPLHQMWSSLITIAIGLYLIYNELGVAFVATIVMTIVIMVVTPYFSREIRPLQTKLSAAGDKRIRLISGILRQIKGIKLSAYEPELIKKVSEVRTAELQARKKFWKKFYLIVCTTSVTMNALSLATLGTYAIISFLSHSQGLTTARLFTAYTAIGIITAPIYAIGQNYPRVLAAYACIKRLEGYLLSLESTSSQSVNSSSASAFDSETEGSTKGDVVSGIQEITYDEKMNTYEPQISGTVSFRSACIGWSEKVLLYDLNAEIQVGMITMVIGRVASGKSTFLHSLLEETQILSGTISYPWKRGSIAYCSQTPWLQPSQSIRNNILFASNYEEAWYTEVIRACALEFDLEKMKNGDSTLASGLSGGQKARVALARAVYSRKPVVVLDDVFSALDGPTANSMFEALFSRGRGLLTHRTVILSTNKMAHLNFADWIISLNESRISTQGTYSDLRGVEVLKEVESTVEDTSLPNGPVSGPKKPSFKMEELPDYTKSIAMRSYMHYCRAASWYCIAVYLLLLLLTVGIQTITPVYLQVWSTYNDSHFSNRKSVVAYLPGYAAIEIAYTFALCYVFYYMIMILSQNASRNLHEWQFSAVMHAPMSFFDSTQVGQTINRFSQDIAYIDGGLPLALYDFFYQMVRAIGGIIVMIIALPYMAAVVFGVVVVFYLVQWFYLATSKRVRRLDLASKSPLYTLYQETMMFDALLTVRAAGAEGHFLDSSEILLARSQRPFYLSRNVAAWLVSSIGVMTSIVNTSVVLLAIGTRRSASAGLFAAAMSQAISLQDMLNTMLTSWTKLEMAAVSLERNLDLVNLVPEDDDDKSQGPGVLDDNEWPSRGEIELTNVMAKYRVTPILKDVSFHAPAGSSLGICGRTGSGKSTVLLALLRALQVEGEILIDGKNIMNISRRRLRKGMTMVGQEPFLLDGTIRENLDITGCKSDDDVWAAIESAQLKPAISKLNGGIDHQIQSISPILSPGQIQLLALARSLLSGKKIILLDEATAALDGETDDSIQEVIRSSFKDCTCITIAHRIKTIKDYDQVVVLNHGLVEEMGDPAELLQKEGSVFRELAQASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYC9</accession>
    <name>A0ABQ8VYC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoprotein TPR/MLP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_749767</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057974">
        <property type="entry name" value="NUA/TPR/MLP1-2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012929">
        <property type="entry name" value="Nucleoprot-TPR/MLP1-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057577">
        <property type="entry name" value="Nucleoprot-TPR/MLP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898:SF2">
        <property type="entry name" value="NUCLEOPROTEIN TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898">
        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25481">
        <property type="entry name" value="Nucleoprot-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25785">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07926">
        <property type="entry name" value="TPR_MLP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoprotein TPR/MPL1" evidence="7">
        <location>
            <begin position="238"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="NUA/TPR/MLP1-2-like" evidence="8">
        <location>
            <begin position="543"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoprotein TPR/MLP1-2" evidence="6">
        <location>
            <begin position="1114"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1113"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1228"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1767"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="68"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="498"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="632"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="758"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="881"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1265"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1353"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1571"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1117"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1235"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1785"/>
            <end position="1834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1842"/>
            <end position="1856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1914" mass="213839" checksum="08F66B6D16623FAA" modified="2025-10-08" version="1">MVGTRRTSKFPSNTEDEGGPSTTEDSHNSSFTVPIPEDFDIEAFTSLIPDFDIHSPSPESLVNLYQLLLEQSGAIDAAQRDVDELRAESERKDVELDQALQDREQSSKDMEQQVERLQEELTQVKQERDHLCVLNLPFLYVNWLIHSFIVPVASQNELQTRITGLASSQTSSSREAEELKHRLEDTEREKRDLINVISRLKQDGSERDDEINALRSNLKEARAEHQELDSKFREIRATETSTKFKLDSLTQQLHLAQSEVERINVELTTKSEEYGNYRRTKQAELVALQASLNDMTQNHSSSQANLKALQTSHASQTHQLTQALTKVQDLNGQIAEQEATYSTETNSLHRLVEVLEAREKQAKDFVENMERDWAELGERADEREANLKADIEKEKRAREEAENKIEQLEKVLDKMGRGELPIPGRGAAGTPSRRTSGVFDEVHDGLVGLSPTIAMVSKTQKSGKSFTEVYADYVRLQDLYEKKCIESKNMEAAMEDVLAQLEERAPVLSQQRIEYERLQSEASQLASELAQAISDRDVQYHAAQDNAQKLHKSSREIDLLQQQLDDLGLQVRALLKEIGRRDDPNLPSDEELENVIAAEVVEDVITNNLVLFRSIDEVQLQNQRLLGIVRGMGQEMEEAEKKQKAKMEAEQAEAVREAHETMENLAAELDRQRKHSDNVIQAYVKERDALKAIIARSNHNEGHTNIPTDSSEIGVSDASSSVAKELAEIQSQFDTYRTEMGVDSVKLREDNIAAHREIGQLQAALAKASAKNENQIERLRMLQDQIGLQNQELNDLTKRNQQLLDQWTRVDVECGRVTEDLHVTSGRVEQLRSECANLRAEKGIWESIQSRLVEENKSLALERSHLSALMSNVQRMHSELERSGENDRRRLENQLQLTESQSQELRNQITQEREAIRNLSLQKDIEVRDLQNRLDKSTQELSKTREALAIAETSKVHLEERVGDLTKYMKGNEEKLAVYERHGGAYSSMEQSDLTREQQLESEVAGLRSTLKIAEFELTQAKGHVQQFQSISEANEIALTEFQSTHEEYIASTDAQIAKSESDRRVLEERLQIVQTELAELTTKHNDLQKQYEDDRIAWSNDKKTLEDTIVDLSTSENDRNSHENDVKQQEERAKVAEERYSNEVLSHAESIKALDNLKKQLASVQATVRDYQVAAETAASKLATSEGSWQQQKQTLDNEAKDLRQRCNDLTEQNNVLHHHLETVSSQAARIRQAAETTTSTSSEADANDSSDVKLSEMRSVVAYLRKEKEIVDLQLDLSKQENTRLKSQIDHLYQNLNETRQTLSEEREKAVEAAASGAKHEELIKRINQLNILRESNATLRADGEARAKRIKELETKLDLLGNQLEPAKEEARVTKAELQARDTQIKRLEEENRRWQGRNQQLLTKYDRIDPSEMQALKDEIERLKAEKSSSENVIKEREDELNQTKSRVEALEKALATYKETYAKNMNSFKSKLGELNAVRSKLTTEKKELEEKVSALEGQTRNLEATLDSLKTEKESSGSASALPDGAADPDVVALRAERDLLLAEKASWAASQTNSEVLSSWDTEKAALIAAREQAETALKTATEKAESASNTAKSNKAAFERLNQRLQALNKAREEDAHKATAALEAAVSAAVAKVKDELQTRETPPDDFVAKHQAELKALEVRLIAAHQEELKNATGNKGPSTSGSEIDVQAAVAAAIATHDKERDAKIAEEISAAVERGRMEAASKMKLRDSQIVRVQTKLKEYEAQIQTWKQEGILPKDAKVSPLSGKAPPPPSPSTSSNLSTPVTPSTAPAPTTASANASLPRKPSVPSATPSSSSTIVSTPPGIGRGRGGPSAVRGAIRGATRGAAGTGRGAKPSQPLSGGITIQGAAKRPAPESAADDTLAKRLKPAAGNPVTLRRPPPPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYE4</accession>
    <name>A0ABQ8VYE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-reducing end alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_942764</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055235">
        <property type="entry name" value="ASD1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051563">
        <property type="entry name" value="Glycosyl_Hydrolase_51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776:SF0">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22848">
        <property type="entry name" value="ASD1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045128767" description="non-reducing end alpha-L-arabinofuranosidase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase C-terminal" evidence="9">
        <location>
            <begin position="447"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="625" mass="67451" checksum="11FF48FEA4BB115A" modified="2025-10-08" version="1">MLPILLTSLALLCVSVKSQITIVVNGTASHPIPSTLLLQNRAFQMVDTTDQTTALNAWHSVNGAQLTVIEETVPVSSALPNALSVVIPSGSSGQVGVGNEGYFGIKVNSSDTYNASFFYRFPVASSFNGTATVGLQSSTGDFLGGTNVTLSGSQTSWLQVNTTIRPTITPDSLTNNFTVTVDGAELAGQTINFAMFSLFPPTFKNRPNGMRIDIAETLSAMAPSFFRLPGGNNLGQTVATRWQWNNTVGPLVDRPGRVGDWGYVNTDGLGIFEYLTWCEDLNMQAIMAVWSGFALGGTSIAEDDLGPYIQQAIDQINFAVGDPAESDAAALRASLGHPDPFPVVHVEIGNEDFFAADTYTYRWNQYITTLQATFPNLSFLATSDTFNPILIPNPAEWDIHVYQTPSWFAENSFIYDGFERNGTHYFEVPISPNPDDLFGTPADGRLTFPTIQSSTGEAVFMIGLERNSDIVFAASYAPLLNHVVNSQWTPNLVSFDSGNVYPSTSYYVQQLFSVNRGDEYLPSTLPDADGTTFWSVVRKTSVVPNEIIIKVVNTVGAVSNVTFQLPFSVEDTATVQLLTGAETDSNTPTAPKMVTPQLSSLVVGETFAYTAPGFSVSILTLITSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYS9</accession>
    <name>A0ABQ8VYS9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal membrane protein PEX13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_787270</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxin-13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007223">
        <property type="entry name" value="Peroxin-13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035463">
        <property type="entry name" value="Pex13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19332:SF1">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04088">
        <property type="entry name" value="Peroxin-13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SH3" evidence="15">
        <location>
            <begin position="327"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4500655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="414" mass="42947" checksum="DFC733B8EEA38D08" modified="2025-10-08" version="1">MGSPPKPWERAGGAVSSSSVPSIPTPTPSVSSTSTVVANPTPSPSSSIPERPPGSPSTATTTALASTNASPYSYGTSPYSRMGTYGGYGSYGGGLSSYGGYGGYGGGGLGSYGGIGGIGGGYGGYGGLGMGYGAGMYGGGYGLGGMMGPNGVPVDANGNPLPPSLTQTLEHTTQHTFALLHSIVQTFSGVAQMLESTFMATHSSFFAMVGVVDQFGHLRNALGSVLGLFGLIRWMKELLTGNKSSSGGLPGEFRQFVNGRPVQSPSGPPPPRPSKKPLIIFLLAIFGVPYAMNKLIKTLAARAEAQAASGNPIAGQLDPSLTPLDPSSLTFARALYPFTATNSSELSLAENEIVALMAKWDQARGIEVDPRVDLQGGIDAEWWRGRTREGREGWFPRKWVEVLQRKPVSQKVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ74</accession>
    <name>A0ABQ8VZ74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_9121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF3">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="674" mass="74562" checksum="EDDC991B48E206F4" modified="2025-10-08" version="1">MCDVESVRIFTYCTLSFNHHISLTFSSLPLYTGYSDIVMFDENPNPVMQHDNRSVPYLPSERAPDTVPPLPTYEAAVESFSNLTINDARRDPIPRSTSSMSMRSLQSIQPPQHQRMMDPSRHANGLPPAPNYARTYASHEPISPRRDNYPESDRMTVSSHDDRSIASPDSFSSGQSTQSWAGYAQPPQHGWPPNGYDPYMSAASSVLGMAPPPGQQYPPSQGPYNPNPHYHQYANSQVSLGSNHSGSYAAGYAASVASFPPPNGRATLPPVSDTASEIEPRPSLARGESLLPATNKSKAVDLSTPPYTKQYIDSYRQRIKGDPDPEAHFLYAKYLIDAARKIRTSSKDQRSAKKYSELLIGEALKVVRRLATQGDAYAEAQFFLANCFGTGALGLQVDHERAYHLYLQAAKQNHAAASYRVAVCNEIGAGTRKEPPRAAAFYRKAASLGDTAAMYKLGMILLQGLLGEAKNPREAVGWLRRAAEQADEENPHALHELGLLYEMPNSGLVPHDPIQAKNLFTQAAHLGYTQSQYKLGQCYEYGALSCPVDPRRSIAWYTKAAEKGDPEAELALSGWYLTGSEGVLKQSDNEAYLWARRAANKGLSKAEYAVGYYAEVGIGINQDIEFAKRWYMRAAAQGNKRAMNRLTEMKRMGNKRMNIVRPTRQQAKDECVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZA7</accession>
    <name>A0ABQ8VZA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX hydrolase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_912997</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF1">
        <property type="entry name" value="ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="51"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="22866" checksum="4FEBBCA1ABD027D3" modified="2025-10-08" version="1">MSQEPRVVSVTDLPTNEAKQVWITLKKIKYTDAEGHERLWEVAQRKTRKSSGIDAVAILAILKSKANSFPPSTVVVEQYRPPIGKFIVELPAGLIDEGETPEQAAIRELEEETGYKADSVIESSPILVSDPGMTNANMKLVVLNVTLEDKLETPDQKLESGEFIVRRVVELKELLNELRAYDSRGFILDARLHHLAAGYAMALNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZT5</accession>
    <name>A0ABQ8VZT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_807799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="103" mass="11796" checksum="205CF747C81801E6" modified="2025-10-08" version="1" fragment="single">MIVRPVKQHIPMTKLWLERSGQHPLTVYIDHQGLEFEETFAATDAVIDLLRPHVHRWKAVTFILASGIHSSLLALPRDEYPLLETLCFDTTGVYCWSPDAIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W013</accession>
    <name>A0ABQ8W013_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="109" mass="11933" checksum="78587E1FCE5E11BF" modified="2025-10-08" version="1">MSSPSSLFPTLAARSALIQQVRQARIDDPDTIYLGFPLASQRPIEWVRQGRADVLAWKNSESNDKSEEVETNGHTEKSAPEAAVLSLIMQLSSANFWMSSNGGWKAPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0H7</accession>
    <name>A0ABQ8W0H7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_913148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="44013" checksum="746DDF7AA21E1AD0" modified="2025-10-08" version="1">MATTSFQGMPPEILSRIAFYTVDCATTVVALPLVCKQAYIASIPNLYAKVTERALPTLAKPSSECQELMGCRHPAYYVEHVRIAPDITNDTFVTYFVDAFNNVSRYAKNKKSFTFQPFYLCDLRPVPRMANFESNGFEAVSLRCSTPPILPVDLFSSLMTALCSRMLRNLTLDFHMVSVPVIFPVAANALNNVQLRCPSLRTLHIVFDALRQGPMTAMNALFHSTSFVFPHLEDFHLFDIDGDLDIAAFLLRHPKIKKLGYVPGWTVDLSSFLKDPRLVPLLECFSGCGHVVPIVASYPFRPLTTVIITDWKPETSKLGHLIDGLLQIPSLHDLCFLQIDCFTIDELRMFESMFHTLELFECNLIANSSTPDVSFALFYVVTSISLVFRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AKL8</accession>
    <name>A0A9W9AKL8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8J55DRAFT_509264</name>
        <name evidence="12" type="ORF">C8R41DRAFT_814060</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000011">
        <property type="protein sequence ID" value="KAJ4484908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AKL8"/>
    <dbReference type="OrthoDB" id="10250970at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052092">
        <property type="entry name" value="SF3A2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031781">
        <property type="entry name" value="SF3A2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205:SF0">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16835">
        <property type="entry name" value="SF3A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4484908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="220" mass="25357" checksum="B14715002063EC28" modified="2023-11-08" version="1">MDFQNRVGSKFGGGGVAGASETNVDRRERLRKLALETIDLAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDAKDTQLMIAPTQSTIQRKVFLKIGRPGYRVTKVRDIETGKEGMMVQVHLPQIKAGVIPRRRFMSAWEQKREPPNKAYQYLIVAAEPYETIAFRIPAREIEDESDDAGYWNWSHWDPDTKQYSFQFMFRLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AXL1</accession>
    <name>A0A9W9AXL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Chromatin modification-related protein EAF6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_504380</name>
        <name evidence="11" type="ORF">C8R41DRAFT_593418</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000006">
        <property type="protein sequence ID" value="KAJ4491513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AXL1"/>
    <dbReference type="OrthoDB" id="440324at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13476">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="132"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4472421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4491513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="180" mass="20260" checksum="B8B11AF360FB599D" modified="2023-11-08" version="1">MAEDVKTRYEAIKKELLAQIPKKRAIDKKLAQVEAQIFTLEGSYLSETGTHSGGNLIQGFENYLKNQTTGRRRTEAAEHDRIFSSSSLTYTRSLELMSEENGDDEFVKQTSTGLTTVVVPPATRSEGLTAAQQNKLMRDKEYQRRKRASTRRSAGTISDDDSVPTLGRRPTKRARLMDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWM7</accession>
    <name>A0ABQ8UWM7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_861281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000160">
        <property type="protein sequence ID" value="KAJ4463531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="59" mass="6653" checksum="4221B9A76E5861C0" modified="2025-10-08" version="1">MTLAVIELLSFYVTVAVVLFFFKKCFHCQTAFRYSFQLPSSCAGCLLVFPQAVITIDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY59</accession>
    <name>A0ABQ8UY59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_891163</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4465608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="512" mass="58284" checksum="65DF393819BF28C3" modified="2025-10-08" version="1">MWSTVLLYIGVILITFRVVKTLRMSLRSKLPPGPTGIPIIGNLFQLPTSRPWLVFDEWMKQYGPIIYLNIAGQNTIVLGTHKAAADLLDRRANIYSDRPDLVVLNLLTGGMHWAWTQADESWKKKRREAHEALNAQAAKEYFPYQETESVIMLDQLLAHPEIFTDHFQRASTSLTLTIVYGWPPLLDSAHPNAVHIDQMDHELLVAAAPGSFWVEFKYFRWMKYLPRWMCAWRRNAEDAFSRNSVMLEGLSADVQKQMDAGDNITCVASKILQNTGNLFEASWNSISIYTAGAETTSGQLAWFMQAMILYPEAQLLAQDELDRVVGSERLPTFDDYEHLPYIRATVKEILRWRGVSPLGIPHRLSEDDYYEGYFLPKDTTCFVNVWSLHHDTQVYGDDAEHFNPKRFLDANGNLQSSIVDTKDEGHYSYGFGKRICVGRYIANNSLFIHIAFLLWAFNIKAKVDADGNPILPDSLQFNEGLIVRPAPFSCNITPRKMDASEIIAQAKADRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYF2</accession>
    <name>A0ABQ8UYF2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5648 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_734420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043708">
        <property type="entry name" value="DUF5648"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18885">
        <property type="entry name" value="DUF5648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5648" evidence="1">
        <location>
            <begin position="11"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="156" mass="16897" checksum="B74E5132B5540B4D" modified="2025-10-08" version="1" fragment="single">SDCANNANATPFLRAFSSTGKDHFYTTNSTEMNGVAIAQDAYSFEGDATFLWSTQETSTVPLYRLYSQTANDHFYTMDANETSEAIAAGYAFDTDSHIAGYVYPYSICGASPMYRLYSSASSDHFYTMSQAESQSASASGYILEGIAGFALLPSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ08</accession>
    <name>A0ABQ8UZ08_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_857420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045239161" description="Transmembrane protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4466045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="40989" checksum="D950B2ECE7FC83C1" modified="2025-10-08" version="1">MLIVYRRKRKAYKTQMLAMLLLALASTASVIVQCVNQGIELLALWDSEAALKGDAGERSKTVQDNMSTALIHDYAVLGIYIFSNVIADALLLYRCFIIWEKDIRVVLLPVLGFLCNLVLGILGLSYNDEFVFYFWILTIVENIVLTTLITGRIWYINHTSGDLLGSTVKTKYNMIAAIILESGSVYSAIVLVTSITSMMPHNAILASCMLAAATQVVGIAPCLIIIRVALDVDTRVPELASIAIITSHTTRHTMQDPSELQDNILESEEALFPKEMKEDTGIHEQDLHVRVWGQFHSQNTGQCKYSALGDPDDGEDSKLNSTNASSTSMIDSHTHVDDMSTPNPTPNAQQVEFARLDTAVLGWYSLEPSSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZG9</accession>
    <name>A0ABQ8UZG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Serine/threonine-protein kinase Tel1</fullName>
            <ecNumber evidence="4 16">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C8R41DRAFT_925941</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Chromosome</location>
            <location evidence="16">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 16"/>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021668">
        <property type="entry name" value="TAN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11640">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01342">
        <property type="entry name" value="TAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="16" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="16" id="KW-0779">Telomere</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="19">
        <location>
            <begin position="1981"/>
            <end position="2569"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="18">
        <location>
            <begin position="2685"/>
            <end position="3001"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="20">
        <location>
            <begin position="3023"/>
            <end position="3055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="759"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ4466974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="3055" mass="345483" checksum="742B03F3AA64F849" modified="2025-10-08" version="1">MTTESKVKNATTLLHSGKVKERQEGLSALRNIFSQNSSIERFYNVAGRDGRKPSHEIWAPILDGLQTCIRSEKSAFVTAKKSTDVIEKRLAAAAGTYRWFVEKSMMHFAKKTVLEICHFLYREMKVRETLIPSVALDFIKAYECVASHPPHLARLEEDETEWEEIVELSLNVVLKKPLRTPLAKDIPSQDPPSPSHTDNSEMFVEDSLAYNEDEDMDALPGSKRRRGASQPGPAASKHPRFTTSKPVSAEQVACMSLLSVLFKSSCAPLLKSSIVRPVLRSLEGFFEIYSSETSLHHDFLAATLSTLKHVSLNHKDDVVRFAANSWDRLLDLWGTKNKSLKEGLISILRMLFPFLIADPDIGESPTKPWIENLTKLWYLMCGQGDKRWNLDPLSLSAVRLKVSTQDDYQKAFRAKTFRASAQLDPSQALTWAMLELQADCLAKLYQHFESNPVSSTQPQSTQSSKRPRLLENPVTSLLKSVQQPPMRIYNLQILLFFIDRHWNTPHESMQSDIIRTLLDHVTNDDGTVQSWAFVCLAALASADCDNAASLLSSQTLSASAIPPTTIQTRYMTSVSTRGASTWDSVWTHAIRRTNSPQVCRAACHTASILLVYANTGSARQSLVRSSLTSHRVLSEIETLAKDLDVQGPVAPFDSVCTFLSLCLKVANQDVRLYRMQLEEKVLTWLIDSWRPAHMEDPEAPLYLVSDVLTLLEAICSSSQRSSLVCRVNLPQCLIVETLIAEEQTRVIRDYLLDARLPSVKSDGSRPESSASPNEPSDLGNATFMAPIPAETDLVQPRSRERKISTFFLKSLESALSPWQEGSDHTIVLRAAAAKRALDIAVVGLSFESVLVLNGIQCNRRVIQAACKLITSIAKLLDQSQWSIEEKGTVLLSLEPLVCLDAETYDVASWTVLLPPTRGTGIRSQTLKSLLLDDDRRQKTLRLERMKHLKTLWRNPDVQATFSGISEVFKEILRVVMGQPSKLPADAMVVDDSFSTAGRSPSQSLGATLGTAAQISATRQVAGISILFLSVGPLLQQSAGEPTRDKELTELMLEGAELDLDRFLLACPVYFNCIRNQTLNLSLNHLAQFITVLADHLVRYPNVKSEEFNLQMISFLDATLSLWISLANVNQNAADNFRELFDHYSKHLLRGRLKHWKTRDSVARLYDRYLTLDPSQNAWMDHDEQTTSPMYILPMLIEDIDIRVRFRAVVINARLFEISKNPMALYDTIRQKYTTELEHFELMLTRILSLGNIMVVSSAVRRGPYWHLLETCFFSTKYNRHIETLLTGVSQRMGLNKLSDLFEAYAYQLAFSILQGEHNVLQLPVNLLGYRDLKERANETIRAFTPANLVVVGNPTIKEAGRSLFVGHCQATQRQPEEVIRECFGDLVAYQVLVVLDGNSRSAEQVEAKILETLETYDPSVFRETLKDSVDSIAASIMRTLNEQDFTENGSIVHALRTLDGSTGPAPLFSRLTRYRRLEDIDTHMTNLPNFSPKTILKALTWLTTEVPGGDSHALTYHVLQMLFANLQRSFLINEQMRLVNAILLWVVYRHQRTSFDDTTLLHALVRGACSMLGQWDLVPAAQSILEWCFSLYDSRTDPRFPDILIRVACLCHDYATDADDDSQERCQALLQWVDGQTYALSCRPSVCEQVKLALPAWPHKPSEILGPLSDSIDPASLSKVLTDRHISSNKFRLVRRLRDQSQLHIYDHSQFAQTDFWKLKECMPATHQLREEDVHAFASLLVLNQGSINGFGSEPEKKITPSFQVKSRQQKEVAKAKLHTPQSSLILVLLTMLDNHDDDGSRYAAYRTLRALMLTLPLDLFEVLSQFWPAEYRIEICYLREFRLIATKRQIPELSSTLSAAKFIETAQDFSVWISAFAILLADVLSASNPFYAQLCAILASHIPFTTTVLPLLVQTLLQSPDGNSHSLTLSRYFEQVLSSSKTAVLCRRSIIDIVLHLRHIDHDGRDALAYNRWLNVSFLSLAQNAITCGAYTTALLFLELDAEYRDRSGDDGVSRDTEQIMYEIYSNIDEPDGFYAIRTQDHHQFLMRRFHHEKEWGKAFRFHGAALETDTQNATEIEGLLQSFHSYGFNHIATQTLLNSDQENPNIAYQLGWRAETWDLPESNDGYHPGASLYLALRAVHRERDQGVTDAVIRHVLFKEMDHLRTLGSENIAQIREAIQSLMCLSQAIQWRSSSIQDLIVGKCTDVSKWSTFTTVESGFHFDDIESIMATRISLVKSARRKEQRHQIGTMRSPFSQTLLDVEKICLLGLSQAARETRQNQIALNSVFRAKNLEDIPSFVVTEEFASVLWAHKEEKHAVEYLKDLRRVGGNSDPIWQARVTARLGSWTSEACLEQPSFIKHEFFEKAISLIKQNAHDSEGRASVCHQFAKFAEAQYKAALDSPDLIRLNVYKERKEKELRHYEQLKHEQKGRIVDKNLANTIAAVQKVLAQDNKATSDFISSRDAYLKQAIEMYSRCLEASDKFDADVPIRFCSLWLSNFDYDPIQEKLHKALQRVPSRKLVFLAHQIFSRIDKIDSSSQKTLQPTILQMCTEHPFHSLYQLYCLQPPKTQTKIDRRSSGRVSSGRTTELPPTGRSLAAKIIFDKLLNDPTTRTRTAAVQELCDASLTFANFPVSQSKEKKVPDDQPIRTLHLSRGTVPVITAYTPIDPTMRYDPGNCVCVDKYAGEFDTAGGINLPKIIFCHGTDGKKYKQLFKGDQKDDLRQDAVMEQVFDLVNVVLNRDVETKRRNLYIRGYKVIPLASQAGILEFVGNTTTLKSWLDRAHVRYRPNDMRNIVKKLAEQQKSPGSTLEANHQFYVQCMKNFKPVMRHYFTEIHKTPIAWFRTRLNYTRSVATTSIVGHILGLGDRHTSNILMDNSKGEVIHIDLGVAFDQGKLLPVPENVPFRMTPDMVDGMGISGTNGVFQRCAEETLRVLRDESDVIMTVLQVFRYDPLYNWTMSDYKMKKQAEIDDSATTTTMIMKNPENERILTERLGIGINLDSTRAQEDADRALMGVSGKLSRNLSVAAAVRTLVAEATDTYNLGTIFYGWGPYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0E2</accession>
    <name>A0ABQ8V0E2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ribonucleotide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_925512</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-cone" evidence="9">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4468011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="555" mass="62904" checksum="C41C6959CD52C084" modified="2025-10-08" version="1">MNYVDPIEVTQKVVQGVYQGVTTVELDNLAAETAAYLTTRHPDYAILAARIAVSNLHKETKKNFSSVITDLYEYINPDAIIYNRDFSYNYFGFKTLERSYLIRLNGRIAERPQHMIMQVAVVTSVLGLLLSISNLGMADIFAMIDLRKNHGKEEVRARDLFYALWIPDLFMKRVEGGGNWSLFCPSEAPGLHEVYGDEFEVLYERYEREGRARETIPAQKLWYHILEAQIETGNPFMLYKDACNAKSNQKNLGVIKSSNLCTEIVEYSSPDETAVCNLASLALPTYIVKDASGKPFYDFQKLHDVTKTVAFNLNRVIDRNYYPIHEARRSNMRNRPIGIGVQGLADAFMALKMPFDSPEAKELNTKIFETIYHGACEASCEMAKTDGPYETWMGSPAQQGQLQFDLWGVTPTDLWDWNTLKENISKYGMRNSLLTAPMPTASTSQMLGFNECFEPYTSNLYTRRVLAGEFQVVCPWLLRDLVDLGLWDDAMKNMLIAHHGSVQNIPAIPDNIKSIYKTVWEISQKKVLDLAADRGAFICQSQSLNVHLASPTMGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0R9</accession>
    <name>A0ABQ8V0R9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="14967" checksum="71E2BBD068EED573" modified="2025-10-08" version="1">MSPSPSLGPPWTLQEPLQGSHPLTPATTRSFPSLVAVSVAPFELQPAPSTLQHKLLIPKPTLRPILTQVLQYSADALPFHPTSSSQKPLAPSPMMNTGSCPASPTASLSAPSFGARHAPAPTYPLQQDSSRDTNSTPGGPTGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0V4</accession>
    <name>A0ABQ8V0V4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="19353" checksum="A9B33B797AE287D9" modified="2025-10-08" version="1">MDGNTGNGGDGNMNNDQLYRLLQSFMATPNAQGLELAGQNPHPLTLFQSFLCSQRLTQNLPNQAGPYPAFPSVQPSSQAPTTSSQNAHSSLPPSASLPPPQATYTSPSFDPMRQSQVLFQNQAQFPSSQSVPGPIPPPPPSNQHQSLCTSSTAPYPTQWPILQTPFLGSRQALSAPPLSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1F5</accession>
    <name>A0ABQ8V1F5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_925217</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4469184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="47786" checksum="5D76E424CFB4E40E" modified="2025-10-08" version="1">MPRVTSFKFIDESARECRECNLVFDYPYQMRKHMQTHGHADASQAKFRCTWSGCAYSSSQRSNFNTHYRTHTQEKSKTCPDCSFRTGDPSSLTRHRKRIHNYIPNPRKPRGSSSSDKSVSPASITPTFQSTVDFASVPALFSESSSTSDSGVTASDFSPLSLDFGMDPSFDATSLDYSCNPAADTLPLSLGDLFNQPSAFHRFETFELTHCPRPLFPAVDSTASLERSSNNNLQSRSESWSDLSLLFGNNAMPSLEGIGSSDMTHTSDSSFFSSPYDNTWQTNAGVSNFQSYNQCPEVPVQHLQPEHMSYESCAGMDYVTDLDPSTSVVISPEDLKVIFGSKTHHQHVEQDAGFPEVAPCFNLSSYDYPAISQDQTLPFESLESLPFESIDTQPFPLEFFEQVPSTSFPSLSSSSTDPLFDLDQFAASLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1I2</accession>
    <name>A0ABQ8V1I2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_853178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38390" checksum="EA77581AC7C85C42" modified="2025-10-08" version="1">MGHLTLWRFISEQWQTIKPVEKVDLTGKTVIITGGNAGLGFEAAKHFATMSPGRLIIACRSEEKGKAALSKLSQDTGYTQAEIWTLDLTRFASVREFADRFEREGGRLDILVENAGIIGSPSYEKTDDGYVSILQTNVISPSLHTLLLLPYMIKTAEEHKTKPRIVQVSSDVHYRAMGKKNKKFADQSNIIDALSSLDYHNQTPLNSHYFDTKLLNVFFVRALQARLAKYPSIIVNAVNPGYCYSGFRSSLSGARAFIDHLMETLVALSTEEGGRQLVWAAVGGSGSEEKLKGGYVSFGKVVEPSDFSISEEGQALEEKYWNQQLDILKGVDPRVKQIVDEYLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1W1</accession>
    <name>A0ABQ8V1W1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_852704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="31511" checksum="CC33CAE52A09FF9C" modified="2025-10-08" version="1">MIYVHGGSLVAGDKVWYKGSLYANIGDYFASYGIITVIVNYRLVPDVKYPGGAEDILMAREWVYHNISKAEFGEGDPEKVVLVGHSAGGLHLATNLYLYPPEPKPKPNLNTQKYPLPSPPPIAGIVFISTPFIFDSNPTTITTTLIPAQPSHWHTNTQFHSNTQFQTALKAYYGTQHLDEVQELSPIGLMMGKIPDGSPVLDPRRLPCLVVLAQYDPQGIQDSTFAFVDEYRRRSPHGVLPEFVVVGGHNHISHVCSIGTEDDVQGRILREFINRVLVLKGGFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1W2</accession>
    <name>A0ABQ8V1W2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_746879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13742" checksum="AE2A09D68AD7905C" modified="2025-10-08" version="1" fragment="single">VSSAHASEISSVLVNLEKDIEDCSVEIARLQAQIRSQNTKRDFLHHVKQWGQSILAPVRRLPNEILHEIFAYCMLDDTFTVAKDFGMSRQPAWVLSSICSKWRKIALPCKPLWSNICLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1X9</accession>
    <name>A0ABQ8V1X9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000122">
        <property type="protein sequence ID" value="KAJ4465757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045047112" description="Aminoglycoside phosphotransferase domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="17940" checksum="7D0E8FDA31B01947" modified="2025-10-08" version="1">MALSSILITLLSRASVVPTVFENLTADEALSAARSSAGEYYSQSPLTSIVPHDDQGCGSSTFVVNYADGTKAVIQLRDSPCVRSRRLKRIIGVTQQLGEILAKLKLDLPSDDIVDNHIIPRLENVLENGMPDVEDAVILHSDRESLVSSTQPQEASFDTFSYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Z9</accession>
    <name>A0ABQ8V1Z9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_898512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42032">
        <property type="entry name" value="YALI0E30679P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42032:SF1">
        <property type="entry name" value="YALI0E30679P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="263"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4465332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="55538" checksum="D5AA53273E8C30AD" modified="2025-10-08" version="1">MNILERAHSLSNLNHNSSIEKGKGSPVATKTPQDIHGSDDDEVEVSGSTDGEYETESESSRTEGNGSPRRSAFTPRANDDDGRQNTGLNSDHAERRPLAHHPAQARSWYEFDLAVVAALVSPVGQWLTGGDHIKNLLFVLLLVFYLHQIIEIPWTLYYNARPRVRPHSTSLPAAEDFYTRRALSELRFLEFLFFSFTVVSPFLGAYLLRYVTFAVTGQDMHSWFSIGLFILATGVRPWSHLIQRFNQRVTDLHDIVHYHSSVKEGSSEDVVEMKQQLERLHEQMQDMEKLIIKLKKKLAKETNEVYDYVDEQVDSVEKIVKRHEKALEYVLQLPASLLGSHPSKSSINSLSSNGSPSPVTFKHLLRPPSHSGASSPIMTKLETIPEVMEIRTDRQKSNNTPLRPKTVLVQSPPTSSGSAVQPIIFRPFFVMVSFMTLPILFFVHVLYAMTLPFRWCFRVFLRLVGLEEIVFRVYDEYSSSFRVYLKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V232</accession>
    <name>A0ABQ8V232_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_777414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="42367" checksum="00B7FB9F2639B536" modified="2025-10-08" version="1">MQEYLYETCKRGFGQEHPNTLLWKAGVAIILEKMGRYNESLYLGQPLLEILKKVLGEEHPDTLNRMQHVALTLKQLARYDEALDLEQPLLEISKRTLGEEHPDTLNRIQYLAVTLGHVGRYNEALDLQQALLETAKRVFGQEHPDTLTKIEGLTYTLIQLERFNEVLDLQEPLLESSKRVLGEGHPDTLTRMHNLALALLYLGRNVEALALVQPLLEISTRVLGEEHPTTLFRMKSLADIFGQMGMYNEALNIKQSLLETSKRVLGEEHPDTLNNIQSLARAFGKLDQYNEALNLEQFLVESSKRVLGKEHPDTLDRIQTLAYTFTKLSKYDEALDLQQSLLETSKKILGQDHPDTLLDGVFSRFNPLTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R2</accession>
    <name>A0ABQ8V2R2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4471180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="27823" checksum="8B68190AB601426C" modified="2025-10-08" version="1">MIALFTQFLSNKLLPSNQSLKAGVKGKITKHNMNMTKGAKAMEKIIKITEAIECYQYYGAWQGDNIGYCTLAQGNIAGSVFPDVVNPAAENPNTKTWHLNEIHGSRFICLTCIKEDFAENIDLCSQCRNLAVKRKCFIHEVSHPLLQVDAVILDAELALAIPKSQTIANQVEDHPPTGVISVSNVHHLIRVRRAHVSVSTDRRLELLEQQDTDTAKPYDERIGYRITKHWGGVISISLEERKLPERSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3W3</accession>
    <name>A0ABQ8V3W3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_780181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045007165" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="173"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4466803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="685" mass="75040" checksum="98CBB3D6A249C898" modified="2025-10-08" version="1">MRLVTVPLLTIYLSNLFTPGVQGVSERSVSLLFENDGNWENLANRTSALLFYDPETFDDASQVCQDFDENLLDIQGLSDIRNKLSYLRYQGEFNEHTKFWVASNTTDGGSAIALFTPNSSASNTSSSQKLPFLCSNSAPLTSQVDTDFASLPQTNATSNGIAFTGVRDHLTFRFMGVPYASSPTGTLRFQYPVPWNGTYVNARGFRPACLQFGSFANNDAGLNPWGISEDCLFLNIYTSYLPSSSSRPASLRPVLFWIHGGGNLNGMGSDETFDGGPLVSRGDVVLVTINYRLNIFGFLGLNDTAIPGNYAMADKIAALRWVKDHVADFGGDPEKVTIFGQSAGGWSIVDLLKSPKAAGLFHAAISQSGGSGTFTTAEEVYKMVGELPFLSPLCNETGTELLKCLQSLPANVLLNITNFAGSWSTVIDDIYALDSAVNQMALGPDAVNSVSFMLGFMPEEGQSLLGTTILPNTTDFNQSLINAIGSTLAQDVLQSGYWTISEEFDVYNATIDAYTDWFLTCPAENMISAASKSNAFPAMYVYSMQHAYGLSFYDPYELCTFPVGDPQPYYRCHSGDLYEVFGTYHLFSEPLRVPADIFYTNLVQDLWTTFARTGDPNPDLADLAARGPAYESTRQLLVDTKWVWPKYDNMSMQIASLEYPELMTVRGLPDDLNKRCAVITAGSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V440</accession>
    <name>A0ABQ8V440_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_850489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045564">
        <property type="entry name" value="DUF5910"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19287">
        <property type="entry name" value="DUF5910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046497057" evidence="2">
        <location>
            <begin position="30"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="272" mass="30795" checksum="5D834D9887558C54" modified="2025-10-08" version="1">MLSTKSPSFFILFLSALLALALVVSESSALPVDAGPIQHVNSSINWIDLTESDLANATTHELDRRLMQDFNVNDYAKLGYMTYVSKEDAEEYVKLKTFTAIPGPENFRPVGEGAYLDPKVFTYGSSDQHCKVSPLLVSLFLLLLSWLMISQCVAVMPKKTLTETPRLFVPNDAMHMVPQWIDVQKYKESPLLFYKPAESTSVQLVIPFQYLAKSPRYGNEKIYAKSNSKNIYVNCYENDRPLGSTKAEKEVMEWETWNVKHWPTGLKSSGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V489</accession>
    <name>A0ABQ8V489_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_803144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF107">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4467307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="52406" checksum="9935121D90CE0C66" modified="2025-10-08" version="1">MMHKVSKLWSVWICWQGRQHTEFKAMHDKYGPVVRTGPNEISVIDPNAVTDVLGAGGLPKGKWYLARQDERAPSNLLTLTGEKHANRRRVWNRGFNAGALEEYDEILAKSATQLVDGIQARSESQGEVDLTTWFNYFSYDFMADFVFGGGSDMLKEGKDEKGILELLEHHMITGALVSHIPWFFYLGNRIPGATQSTLKMRAHAMKWVQDRLKKGAEIKDLWYHLTDEAAREKEEQPLWKEVVADALMAIVAGADTTSVALTNFFYLILKHPEHYQRVQEEVDRVYADADATDISKQSELKFLSACLDEALRLLPPGLTGGPRQVPQGGRMIAGYFLPEGTQVYLPPYVMHRNPECFYPRTNDFVPSRWLSAADSDSDSENPLSWKIHDRKAFLSFSFGPANCVGKKLARREMLMVISIMMQRFRFAFAKDFDWERWPHTMKDFFATSRGPLRVVARTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4I7</accession>
    <name>A0ABQ8V4I7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_924240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="86"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4472705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="415" mass="44289" checksum="446F373DE26D0DAE" modified="2025-10-08" version="1">MSRVVVNSIPIAPQLAADVDNLKNLVEKDLRRARKHLSPDTIAHGPRAIHEARNKDNHRHHEDGSGSTPTPASGKAITVDDATVTYMMPCIIGGSEYSLLIDTGSSNTWCGANKKFQPDSSCESTRKSVNVSYGSGSFTGTEYTGTVILGGKDSALKLEKQSFAVASQAQGFGGDMDGILGIGPVDLTSSTVEGMSSIPTVTDNLHGQGLIKTECIGISYNPTQSNGTMANGELMFGEVDQSKITGDVTYVPITSTSPASKYWGIDQEITYGSSKKMILKQTAGIVDTGTTLIMISDDAFQAYQEATGATMDQATGLLKLTDQQLKNLQSLNYKIGDTTFELTPNAQIWPRSLNNALGGDADSNYAVFASMGQISGIGLDFINGFTWLQRFYSVYDVTNQRVGIANTANTNAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4N3</accession>
    <name>A0ABQ8V4N3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_617446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="185" mass="20472" checksum="DB882E5F44CC23FB" modified="2025-10-08" version="1">MIAFETSVVLFTTIRTFQALRAGGPWRRQKHHLTFLIFEEGILYFCVVAVLNTTSVILDIRAPTGFLQRLLDGFTLPLSGAFTAQFILHLRAWQDKHAGVYIISTVEQVRVLHDGIPLSSSDAMNVDVEAIFRPTPSMDEFGEDPVNRVLRLSSRSESGTIVVAVDCQVHGGEDDHVPLPPDVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4N8</accession>
    <name>A0ABQ8V4N8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_857583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="141"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="283" mass="32116" checksum="B2DDEA4BBAD867F0" modified="2025-10-08" version="1">MSIPEITFDLFKQAVLPVVEESSVEKAHQKLRRRGILIDEGWKEINFGLGEQEQEQEVEELKVNMEIEVEEVEVKKKEKKESLFYAPLFEGLNSIMGADSAVKFSDHPGKHLLSEDDHSHYNADVNGLLTKTTAVPPIVEEAEYECDVLMTGELKKKSTPDTVDDNNKKVLSNATHIMGADPTRRFMFGLTIDKFNVRLWFFSRSHVFVTEAMNLHMDAKNLIYFALSLSGACREELGYDPTVRRVQGKNGTGPRYIFTIDGKQYITTEAIAVRKAKFLLGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V570</accession>
    <name>A0ABQ8V570_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="389" mass="43129" checksum="EFDBE6EC569CBB14" modified="2025-10-08" version="1">MSSTKLFKPIEVGNLSLKHRVVLAPLTRMRCDDQHVPQLPVMREYYSQRAKSPGTLLIAEGTLVDPKAGGYPNVPGIWNDKQAAAWKEITYAVHKNGSHIFLQLWTAGRDADPKILTAEDPSYTLIAPSAIPIRGHDVPRALEVDEIKSLIQSYVRAASNAINKASFDGVEILMANGYLLNQFLEDVSNNRTDEYGGSIENRARLGLEIIEAVTKEVGQEKVGVRFSPWSTFQGESCLIFPVATRFNVLPLDMRMQDPIPTYSYIVKNIKKLYPNFAYVSVCEPRVEGSTTRDTPIISTDSNDFIRDIWAPKPLIVAGGFDRATAIERADSTGDLIAFGRRYISNPDLPKRLFKNLPLTPYDRSTFYLPGDASGRGYTDWPAAGESGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5I8</accession>
    <name>A0ABQ8V5I8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="532" mass="58632" checksum="02482585A31B13CE" modified="2025-10-08" version="1">MDLRDTLSQDSRELSLSPILGEQQLPNVAEVVGSPVLFSHQLASQFELGDIGRTELSEVAKASPSTSITGLIADLFLVFSVLFKTHENQQALQLEVAKLTLKVEAISNSIESTPTLTKPHKDDILTACKLVVYNPVRIDFENDSIVQDGNLKEHSSSNSFKIFFVQESTNMKRVIKDHIRIQASYAKSAFRNARHFARKERPDLFDASKVKAKTRKPTKRARLDGDNFVVNSQVTTVSSSTIPILPIPSGATDTEHDSQNVETEEPESKAIAWASGFTEWINGKINAQVRFHQNSIYSHANFSCSFYEELIKEELLLFPQDLIPNIPRQRAPSVPHPTAVSSNATMLTSASNQNQTSNFFAAISNQAGAPRSSPSTQTSMNTACSNAPVQNPFTGTSSPAHSGRHSSTLPRPLMRSNTPTWMGSRSNISTQGTARPPFLDMLLNTGRPSMPTGLLGSSRLNSTVPISQGHDQNLEPREPLRASERTHSDRYDDPSSPRNDEHLSDSQWSYTQSPDPSFSGQQSQHSHSRRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Q9</accession>
    <name>A0ABQ8V5Q9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity nicotinic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_846826</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF51">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="51"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4475847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="485" mass="53497" checksum="D9F931707998FF51" modified="2025-10-08" version="1">MSEVAPATKKPSSTTSIEKIADGGYGEELLSTDLVSESELKRIQRKIDLRIMPWICLTYMFMRLNVNTVGNIAIINAEQKHDIKTQLHLSPSQWAWVISCFYYTYMGIEPFSTLMMKNTSPSFWISRIMVSWGIVACCGAAVQNYAGLITIRTLLGAAEGGFFPCILYYLAFWFRPEEITLRICFMLACSTFSGIISGFISYGVAFADGHGHLAGWRWLFIIEGLPPIVLGLLTLFILPDYPDSKATAKFLTEQERHIIKERLYDGAPEKTSATWNTRQAIDVLWNPTFWSFAGIWVGNALGNPTPSFVLPTVIFELGFTNSNISNVLTVPTSVAIFLTLVTCAIMVRKDIWNPFCVAFILQIINLICCVILMTVKQPIVRYVFILIARSASNTVVNILWPSRVAALKGTTAVGLGIALSNVLSNIDGLIGPLIFSTVYGPSYHVSYSICAGILTVGIISIAVTGALVGRPVFRPLQALNSSHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Y1</accession>
    <name>A0ABQ8V5Y1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_852168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="8296" checksum="298FE5527C1465C7" modified="2025-10-08" version="1">MTRKLSTESLLILAAITLATKKQEFHVLMLPLFVRAGLLVNKEMTLSRIHKLGVFGSYSLCLKRHSTSYFLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V647</accession>
    <name>A0ABQ8V647_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="49936" checksum="18A1DC82BFD72D84" modified="2025-10-08" version="1">MRRDLSIHLPGDVFTEILEIVRDPPTHGWAQQVLVLASVCRGWREVAVGTPTLWRYIVAPAYDIRFIALSLERSQQCPLVIEYHTKKPNHSVLYLLAKHSERWEHLSLYIPPSSYPLLSTIKGKVPLLKRLALQATTGDDPQPHQQLSGFEIAPALQYLDLQRFYPDLRQDSSTPWVRLTYLCCQSIELSRLYSLLANTPTLSRLHVSDISHDWPYKQSKNEILTQLKVLSIVNCDLRVIYSLLSRFSNLAELSILIFSDPGQANTGLPVILPYLYRLKIQINGIFPGLVNFLVFEALNLSEMEFSGCHSLEDSDDEHEDRIEENAATGRSHLQFLWNFIQSSRCSLTSLVLHFEVDFPTCEMAPLLKALLSLEHLDISVVHMECVPFCAMLPATAVFPKLRRLYLHIPSEAHSIEVINDLIALATSNHILKVWLVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6M8</accession>
    <name>A0ABQ8V6M8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GSKIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_924413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2280.10">
        <property type="entry name" value="Hypothetical protein (hspc210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023231">
        <property type="entry name" value="GSKIP_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103107">
        <property type="entry name" value="Hypothetical protein c14orf129, hspc210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4472398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12478" checksum="8835DD38D2F767DF" modified="2025-10-08" version="1">MNTSEFYINELGRALSEQAPFIQTFSVDSSSSLQATGSVTLLEGNVINIEITNRGFHSHQARELPFETIEDLLQTVSPLYARQRRSVLLEALEKLSSNQPLNGGKDKREHCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Q3</accession>
    <name>A0ABQ8V6Q3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_541387</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF343">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="4">
        <location>
            <begin position="350"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="2">
        <location>
            <begin position="350"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="444"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="542"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="568"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4476171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="704" mass="77277" checksum="9604EB03B0F4C410" modified="2025-10-08" version="1">MTTTDGYHSPISQLLTTLGLTREDLQQRSDEMRQFLTAENSQSSRVGPRGRADSTSSHISSLSRSNSIFSTSAPSLSRASSISFRDASPPVTPVKLEATEAGLPQRHFDSMDVIIERQRQARKEKRQRREKEKDSQRRASMSNGSPTPSSASSRNLIIDSLLQRRDDDQKDVQDQLESLTRSSMEARSPLPLTPQQSRYYREHTVSQSKMVRSRVHAGLAHLLINLLQVVPKVESPVQTPVLSQQLAPQQPKPFYPLPDTVSLTALQTFQASVSGPPVTPHIRRVQTLNEIAERSPLPPSSPFLNSPQSSPVRPIVNLVSSPGPMGPPPEEESYGKLPYTLPSGPYSPNKPDLSYAALLGQAILSSSDHRLTLQEIYDWITIVYPFFKRGETTWMNSIRHVLSTTACFRKATRDRALGRTQWAIWDEDLECFKGGGFRKQFCKDMNGGKTGSEAKTKRGRKQVEDSDGSAEPKPKKVKKDNNLKDSDKAHQRAIAPATAIFPPTRPAPPLQPYRGVSVAKNLTSEVVFPPLPAESGFRLLPVHPSSSSNSRANSHVDADDGIRPSSPTPSVLESQCTDPSSTSSVPDLTPNLSSSSPPQSSSEIELEAPIEIIDGPLCLAPSATVAGLDSEEEDGFQNMFSSSKSSTKLTPVQFWGDSPRIKEFSRLGGKLNFTVPALSQYDDDSEDEGILFNTVKNKSMLAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Q6</accession>
    <name>A0ABQ8V6Q6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_523248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="64" mass="7436" checksum="BC22DC04D56E05C7" modified="2025-10-08" version="1">MFWSLSSVMYKVWIYQCIDVVNHALIDRPEPEHIIFSDIWTSYLGHVVDTDRDPVVSVEQARGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6R3</accession>
    <name>A0ABQ8V6R3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_923397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="103"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="103"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4476268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="30184" checksum="BF83A6C870FD8AE6" modified="2025-10-08" version="1">MSLLSAKFALRLAGTRLTRPLAAPVFSRTTALSFRTFLTTASVHLPTTKAKPKVKAKDVDKPKTKGTRAKKVPAVKKKATPIERVKKVNVKPKFDRKLMVVPKRHGTTAYAVFTKEYMANGLQNKIPVRDLIKTASKEWNALSDAQKQPYSVPIQANKEAFEKRYDQWFRSLPPGYVRQINLQRKEKGKRLIRRPKSMKSPPTNGFIYFYSEYRQTTPSDDMSLPQLSKNAGAAWQALPAEERKKYNHRAHVIREDFFKTHPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V777</accession>
    <name>A0ABQ8V777_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF382">
        <property type="entry name" value="ACYL-COENZYME A OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="1">
        <location>
            <begin position="261"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="563" mass="63028" checksum="81CE0DEF08E83798" modified="2025-10-08" version="1">MSSNRLYEHAIFKIRNEHLSKDESVSLAYQRAKLVVRTYRLTAADVEHCSPKFWSMMTDPICSLDIAMFTILAAHVGLTIGTLSRHLKTRPDLRPLVDRLLRFDTVGIYLLTERGHGLDAFNIETTATKTKDGFILHTPREEATKFMPASTPSFGIPKVALVNAKLIVDSQDRGARFFIVPICNEHEMYRGVISTRLPTRSGTNPLDFSITQFNNVQLPPTALVASDITDFAPPKRPLEAWWDEVWRIQLGTMAVPAPWINALKATAFIGGRYSMHRSIIGKVSNTPIISFRTQQWPVLNATAVAMVMDNWFPRSIKFAMTDTTDDRVRHAMSVIVKATVCRHFQRCVPEMAERCGAQGTFEHNYMAKIENDGKGVIIAEGDILTLCIRLFSELLLGRYTVPMPSASNSLLAQHALGLMEENTEILRSLGDHRSESFNSLVLPQSQVVIEAIGHAMAYAAAGEAKIPQPILDIYECSVIRQDPAWYSENVGLNRMAQRRREDAAVKAALPNLNAYLDALRIEDYVSAPIVSDEGWKNYVISLPRHTGNATVEPQQIQHTQAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7B2</accession>
    <name>A0ABQ8V7B2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_776158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14232">
        <property type="entry name" value="GAT_LSB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16980">
        <property type="entry name" value="VHS_Lsb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044103">
        <property type="entry name" value="GAT_LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045007">
        <property type="entry name" value="LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789:SF1">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VHS" evidence="2">
        <location>
            <begin position="27"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="460" mass="50658" checksum="41A8A676C67BA886" modified="2025-10-08" version="1">MSAITFARQAFNREKPHSSITDWVDILTANHVEEEAYDGIPELVDSINLQGLTGTSEASRALRKKLKHGGSHQQYRSLVILKALVENCGDKFKTSFADGQLTDALRQIAGDRTADKRVQKKLKLVLISWHEQFKTDPSMRSVSELYHMCKDIQPAKPAIDPIEVEAAHRRAEKEEAKRKAKSEKEEARKKEEAERLKQKQMKNRPKRAPFNFEQEKPKVLSSIVEASQASSNLVNAITLVNPEKESLQSSERVQDCLAKAKLARKPIVRYIQLVENEEVIGVLIETNDRIIAALEMYDNMSSPDSKSDQSSAIVAGLAATHIGPESELIKLQEKQKAAVQKAKMNGSLRSDPTGGVYADLEDLNFGTLGASSSNLPPPLRPTSMSGESTGVGANTRGSLSDFSDYESSDEETHNARVSSSKYATNDYYASSDDGANGSRGMQTVNTKASIDDPFADPFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8D5</accession>
    <name>A0ABQ8V8D5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_896926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NadR/Ttd14 AAA" evidence="1">
        <location>
            <begin position="20"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="214" mass="23660" checksum="54648515D4C363F7" modified="2025-10-08" version="1">MSEPFVHKVGEPQISGLRAIYIVGPSSTGKTTLCNALATCLGLPPSMHITEVARTVMKEQGFTRADVHSLDMQHAIVKAQVSKDREARRKAAAEATVLGQAVLLSDRSAVDAVVYAALSELKAKSGSTQTLISSADFQEILPFYRSPRSTFVLLRPIKEWVIDDGVRSLEDGEHCHDMFVRILKELNISYIELGEDCRWLEERIAAVRRGASYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8T0</accession>
    <name>A0ABQ8V8T0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glyoxal oxidase N-terminus-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_965174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF96">
        <property type="entry name" value="GLYOXAL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045317476" evidence="3">
        <location>
            <begin position="24"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="4">
        <location>
            <begin position="237"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="5">
        <location>
            <begin position="624"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="737"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="750"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4475853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="759" mass="82400" checksum="68A4BD6A81E2EAC3" modified="2025-10-08" version="1">MNPRPSRPFLLFLICVVLNTVLCIATDEPAWNGHTPPGSNTPKPFTPYYVAPGAKGYSSSSPFIQYKGDWQIVYSPNFNHKAVHSTCQKQATFSFSFNGTGVEWFGNCDKRHGTASVYIDKTLAGVVNTYCNTTSLRLNQRQFSTFNLPPGSHRLVVENSGDGCIDLNDIVVTRVEQPSRPALRRQLHRRSSASGWNLEVDGSTGVNAMQLAVISETHAIVIDKVEHNPLTINGHPAWASLFELNTRQVTPLEMQSNSFCAGGSFLSNGTLINVGGNPVVADHTSAADFGDKDGLQAIRIIEPCDNDGHCSIRISEFHDSVRMASPRWYNTVLRIDDGSAMIIGGSKKGGWINNDTVNNPTYEYYPPKDIHGSNGMPIKSPFLTDTLNSNLFPIAFSLPDGRVFLAANNDAMIYDWKTDTEERLPPIPNGVRVTYPMTGTGLLLPLSSGNNYTPEVLLCGGSTVDDKKPGSQISSQDPASSQCSRMVLTKEGIQAGWEVDHMPDARLMPDAVLLPTGQIIIVNGAGSGISGYGNVVNQVGVSNAANPVLTPVVYNVSADLGSRFNSQGMPSSSIPRLYHSVATLTPDASIMIAGSNPNLDRSEIEYGTEYRVEWLSPPYMRSARPEIRKHKGNVGFKETLSIEVNRLKSDSDLKLVLMDLGFVTHSVHSNSRMVYLDIHRISGNTLSFEGPPSGGVYPPGPAFMFLVEDGVPSEGVKVMVGDGNGPEVNQKAIENVLKSTQPDQYEKSKGNQGSNDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8V0</accession>
    <name>A0ABQ8V8V0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="197"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="43837" checksum="91C1DB591255088D" modified="2025-10-08" version="1">MSSSAQETHDGNVPHRIRPDKPPTLFQPSFNPNMLIQGLSPGELPKSDDILHFFLTPGHKSVYDIVYAAERLTLLTAKDNKAKLVSLRVLGYLVLLAPGPDHKALAEIATAVRTTDSSDIYVLGGIYSDCFVRSFYKFKGSRTPFTPSHPSRPSFNVRVQEIKATILQAPKNHSEAKDKVGHTMSLVSALVRDGYRCVVTGTIDTKCKGFFDFTELKKSGTLRTECAHIIPEATYFGLDKGKKKDYSASVLAVFDRFGVQFDKLNEGNIHSLWNVMTLVQPIHDSFDRLELWFEATGNEHEYFIKTTDETNRLLSELNGPITLTSSDPNVPLPDPKLLAFHAAACRVAYLSGATEYMEEILRDFERLNVLAEDGGSLAILEHAFFQAGLVRVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9E9</accession>
    <name>A0ABQ8V9E9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M50B-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049500">
        <property type="entry name" value="Peptidase_M50B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979">
        <property type="entry name" value="OS02G0221600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979:SF2">
        <property type="entry name" value="PEPTIDASE M50B-LIKE-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13398">
        <property type="entry name" value="Peptidase_M50B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="28246" checksum="0CDED39894945276" modified="2025-10-08" version="1">MASPTRPPLAPPTASSSPSLPSAITPSADQIVVLYVIIAMAVIIFGFWNVPGIRHLINPLKLFTIGAHELFHIIAAILSGGRILRITIDPHVGGATIVEGGQPTFILSSGYIGSSILGGLFVLAGWDTLVAKVMSFVLAVGLILPLKLVRDKLTILLTIIYEGLLIGFWFIDHAGALRWYCLFIGVMNVLFVVWDVADDRFFHKTNDSDCTQFAILYPSIGAHVWATIWIAFQLGVLAAFAVLGIMVFKVPSAGSISSSSDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Q8</accession>
    <name>A0ABQ8V9Q8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40596" checksum="75627BEF3804898A" modified="2025-10-08" version="1">MTCQKSLLSPIRKLPSDVLINIFRSVSEDSILFTESPNEKASRTFIGAIFSLTWVCSVWRNLALSQPTFWSSFKLRLQGVGENSRSVIFRELVLSRIGPTTPIQIVIGLNDPPRRVPATWNILSQFAGRLKHLKVMVLYPEHFDSLLEMITDGFNAGPCFHCLEHLEFWFLYSSNRKTRSNETFQSFKHPSLRNCPRLYHLKVPFLNLADSLDLSNLTCLQITFDFGGSLSTLLQKCATLEILQLGWFNAPDNLSSRFPPLCHTYLSTLEITNIGRQRDNSSAFEMVSIPNLAVLAVKCPISCGPGNPFNELRTMLVQSRCTLREVLFEGIPSYVANVFLNIVRISEDANITENSGRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAI4</accession>
    <name>A0ABQ8VAI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">C3HC zinc finger-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_772505</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013909">
        <property type="entry name" value="NuBaID_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08600">
        <property type="entry name" value="NuBaID_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3HC-type" evidence="7">
        <location>
            <begin position="47"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="NuBaID C-terminal" evidence="8">
        <location>
            <begin position="279"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="355"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4478590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="468" mass="50166" checksum="B1A52D980726BADF" modified="2025-10-08" version="1" fragment="single">SLSKSTPNLSAILSRAAARTRKAFPTKSGECSSATPLSPLADYRPSSIPSFLGRLETFKLVTYANKPASLDAVAASKCGWINDGKDRLVCGLCNASWVVAGKEGLSREAANALVDKQCASLVQNHKIGCPWRTRQCDDSIYRIPLQSPASTVQNIKINAATLDTVLQDVEIKHPLTASQLSSLQSAISSFDPSPDTSLEKSGNHSSSSEISQTAIITSLFGWTVAPERPRSTSTSRSNSRLPSASRTPSLSRSTSVVPVGSPDRPRPLLHTAVSQAMARDTSLVHCVLCQRRVGLWAFAPPKQPSATPSEASEASSPQQPKRNNSILIKRQFDLLKEHRSYCPYVVRSTVVPTLPSSPSVVSVSTPRTSNLHIRSSSSTSQLNGTSGARVGSNATEGWRAILAVVMRYRMAQRHQLSRIEGLMTGDDAEGQRSSQDSIGVDDGVDMMVQGVKARGGTDLLRYVKGLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAR4</accession>
    <name>A0ABQ8VAR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc/iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_848040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF32">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4474568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="40237" checksum="4169A1EDA99D866D" modified="2025-10-08" version="1">MTVRTPSLAIRDDTDDCGSGGGADTFFGLRIASIFIILVGSMFGSLFPVIAMRYSKYVKVPNGIFEFAKWFGSGVIIATAFIHLLSPAIDELGSTCLSDAWQGYPYALALCLLSIFGIFIVELIAFRWGTAKLAKLGFVYDAHGHEAGAHAAPAPETLARDNIEGEKDVRDLSRVMEEARAGSRSSRSVNREDESDLKETSRGNVAVLDSPLTQILGVAILEFGVVLHSVLVGLTLAVDPDFKVLFVVLVFHQTFEGLGVGSRLAYMQKHLPQAYRNVSVYGALLYGITTPVGIAAGLGVRTTYNPDSTTASIVSGVMDSLSAGILIYTGMVELLAHEFLFSDEMRKSSNTRLARCVCTMLLGCGLMALLGKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB74</accession>
    <name>A0ABQ8VB74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="586" mass="64394" checksum="556CB60A0F6C927F" modified="2025-10-08" version="1">MTCASANLQPNALSTSTTTIPTPPRLKTLLKEDLCISRWTESLAFAEAPGHTPWGDVEDHDITPWKPEGSLYAGDTFQMALLKSRQRPSMLRLARQRLPVPNAHHRNALVFEREITLKSEGRTKRWSVQVPAGSMDPDLAGMMMELRDLNSYFKEEEVQADDSVQRLEEGLCSPVDGVYTHTPSLIVSNSQCIIPLSLESTGSLHTVPKILAVRRGNKALPPLSIKSELMNPSPYPSIPTAFLGSPSSYHPTFEFAGNTRSSTAFQDMIESLRSQCASLQVETPHFPALQEEENNFRMIQSCPHVPPASPSARDGDNDWAFADSLLQEFPEFCSKNVEPPNVELQSNKNFLEASITDPAQSTHTISSNDPSNSHLPSPSIAGSVSPTPSSNSPRGILKRCKSVRFAESPLIDPDSVHTAPVQEVVCPSTRHSTGPPIARSLKRPSPLRHTYAPQLKLTSSSAYSSLPLRDAGCQKPTIASETTNAKPSVHLQRTAMKKLGRERMVSSLNKPAKPKSPGPPLLGRSFRNTLISGKENKLIKLRTSSFANRHTMDENALRRVGNSSSPSETLKSRMPVPLRNILTRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBD4</accession>
    <name>A0ABQ8VBD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_982241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13971">
        <property type="entry name" value="ADCK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044095">
        <property type="entry name" value="ADCK2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF1">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="207"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="295"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4485183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="706" mass="80242" checksum="EED30A4D81A8E69A" modified="2025-10-08" version="1">MSSFHNPRVFPKSVFSTKFMKRHASNWSRAHYSRFPSFFTPTPIVKYDLKRRALWLIPIAGGLALYFTPPQKSLIPTLISSPAVIPCRSSDYTEQSPVILSPFEDDLSVGSRLWLVLRDKIWEPILTAKRFIALCFIFLPVILTSPMLLVGKPQKKYKRDGWGAIWWYGFLARRMESAGPTFIKLSQWAASRADLFPAYLCEKLGALHSHGKPHSFRHTKRVIEQVFQRPFKQVFEEFDDEPIGTGAIAQVYRATLKKDLIPPSYLGPRRHKKMPAAALNSVTLTNPPPSVPTAAVAIKVLHPRVAKTISRDLSIMSFFANFITLFPGMQWLSLPDEVDVFGQMMFQQLDLRHEAENLLTFESNFGSRNVPVNFPRPLQVWSTPHLLVEEFQNALPLETFLKNGGGPYDEQVATVGLDAFLNMLLLDNFVHSDLHPGNIMVKFSKPASTRYLLENLWTSVTHSFFHKSPEDPPDRGIIVPDYSESDSIVERLRSMTHNRSAWLNELSSLHESGYIPEIVFIDAGLVTTLSAENRRNFLDLFRALAHFDGYRTGQLMVERCRSPELAVETETFALKMQHLVLSVKRKTFSLGQIKISDILTDVLRAVREHHVKMEGDFINTVISVLLLEGIGRQLDPNLDLFKSSLPILRQLGSQMARKEPVTKDLPYTNLGAFIKVWVWLEARDFIAASIVNADDLVKFGWLTPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBR2</accession>
    <name>A0ABQ8VBR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pkinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_843970</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11651">
        <property type="entry name" value="YPK1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="205"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="10">
        <location>
            <begin position="463"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4478924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="541" mass="61085" checksum="CA2923BCF42B99EC" modified="2025-10-08" version="1">MSWKLGKGKEPKDSGLNPSRSVTPIPSRSTTPRPSNGTDQFRSGMLTIRIFSGRSLALPPNVPLPDVIQKALESTPPRRSTSNRESMQRKRYWWLPYVVLEFDKNEILIDAMGGDLASPVWNYKANFDVSRTSTISVSAYLRTVAMQGPDDMGNDLLLGRVDLTPVLDGHHASDQWYSATAGSGSFHLKIDFKPTRNETLTIEAFDLLKVIGKGSFGKVMQVRKKDTQRIYALKTIRKAHIAQRPGEITHILAERTVLALVNSPFIVPLKFSFQNPDKLYLVMSFVNGGELFYHLQREGKFDQDRSRFYAAELLVALEHLHGFNVVYRDLKPENILLDYTGHIALCDFGLCKLNMSETEKTNTFCGTPEYIAPELLESQGYTKTVDWWTLGVLLYEMMTGLPPFYDDNVNTMYQRILTDPLNFPPDMPSEARSVMTGLLQRDPAKRLGANGGEEIKRHPFFAKYIDWERLIKKGYPPPFKPSVESVLDVANFDPDFTNEEAQDSVVTDSALSETVQDQFRGFTYNPANEHLSESVSYPSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCB5</accession>
    <name>A0ABQ8VCB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclophilin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_896295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01925">
        <property type="entry name" value="cyclophilin_CeCYP16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="243"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="390"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="447"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4486997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="506" mass="56638" checksum="415FD49BD95BDEC8" modified="2025-10-08" version="1">MALPTNGRVIIDTTVGEIDIELWSKETPKTCRNFLALAMEGYYDGVIFHRVVPGFLVQTGDKTGTGMGGESFYGEPFEDEIHPRLRFAHRGLVAMANNGRKNSNDSQFIITLDRADELHGKHTLFGRCIGDTLYNVMKMGELELDANERPVYPPKIKGIRIIDNPFPDIIPRITAAERRAQQRAREEALKEREEYERRKNAKKRELDVKLLSFGVDEGDEEEAIAFKKKPIVRPDLIDQPVAPSVSGVLPDFVTQGSRTTSNNLEKIKDQEKTKGDVDQEKKSKQGRKEIDLSKIREAHAAEKANSTTARQTEISKMEAEIRKLTKRRDGVDDDSDDERKKKKPKTSYLEAELGKYASSRGIKKKGSKGKGRAKDESDVLNVLNAFRGKLQTALPAEPEDDSEAKIGDDGTEKAKETQPTPANFPVGEDPGIEIDDDRGFLGHSLHFPKDDGEESRKAERDYEVIDPRQRGARAKEEEKARKAKAKYRDGGRGSRGRGSSGGGYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD26</accession>
    <name>A0ABQ8VD26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_920718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="87" mass="9607" checksum="8B36F9A79F8FFCF1" modified="2025-10-08" version="1">MGLTSSYEPLPQDVEDSEKIPTSKQHGNERLLFMIVLFLAVLNILLVFTTTLKASNIFSGILPEITRDDLSSLPRPDPYIGLSLSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDE2</accession>
    <name>A0ABQ8VDE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exosome complex component CSL4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_840178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039771">
        <property type="entry name" value="Csl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019495">
        <property type="entry name" value="EXOSC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE CSL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10447">
        <property type="entry name" value="EXOSC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exosome complex component CSL4 C-terminal" evidence="4">
        <location>
            <begin position="91"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="186" mass="19911" checksum="D6CC60B45AAF34C8" modified="2025-10-08" version="1">MASDIVLPGQPIPLPKGPVPQIGRGIYERDSQLRASLVGVPRFEGSSLVISRVRPQPPAPNSVVLGSITRLSPLQALLSITVVDGVPLPPGEEFTGVIRSQDVRATEKDKVRIGDCFRGGDVVRGIVISLGDARSYFVTTARNDLGVIFATSEAGATMEPVSWQEMRCPRTGKVEKRKCAKPEGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDX0</accession>
    <name>A0ABQ8VDX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_383892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045750499" evidence="2">
        <location>
            <begin position="21"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="577" mass="64614" checksum="2E778C39444D0E59" modified="2025-10-08" version="1">MLPTMKRFVGLFLAFTLLEAAQIPLEALPTFNLEKNDGDNWDISIAPGENVTGHLVFETVNSLMQHWPNTRYRNGHSIVPGVVPSGTVLYHGRGDANTPTNPEWLATDPEHSYMFCRGQTADSGCWQLMVTAIRPLKVLYLDGSAAAKMPDGAMDSQDILAYGKVVPEKYRGERERIKYLCDWTKDLDVDGFVRMEMDFEIMLCDFTKGVLVEAINLRSRPRGGPGPGGPGRGPGGPGGGPGGPDRHLEELLPPPEIHPHHDSSYTPKAHINSSALPNMGFSESINSGSWHRYYPGETRIQLDLTRLVSFYDTDLVPSLVAERYGKERIRHRLLGISPEDIQTVVRKVEELTAVSEAGSGIDWATLIRLIVKRYSERLEMVQYILNSTNPANSAAENKVLAENIQVQLTAMLQPYMLFTIKPPQNSTSTNWVSPMYELCATTYTNYITTSSLHSRLTASEDLILDGVQKTTKEICRVVTGMWVDGIMSGLEPDFYKSSATENDGNVDLAPLLNSWKERIFGLMKWLDWSVWLKCRPACGFEEMCYLPMWPFRRGSEDSDDPQPRCERRMAPLEAQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE14</accession>
    <name>A0ABQ8VE14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein-like 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_838888</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Possible regulatory or functional link with the histocompatibility cluster.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF3">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="6">
        <location>
            <begin position="352"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="553"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="560"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4485156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="633" mass="71984" checksum="763B7F7E46792251" modified="2025-10-08" version="1">MPRRQPTSTRQKKEERQLKRAVKRGEVSPPPPKGRKKPTKRSRVLHSNAPASASVESSRKLQSSFIKSSRQFLENTKTLASTIPLPRPIPPTAAILPQSYEQSSEFETLTCPRRPKWRYDMSKKEVESNEEGLFKKWLQDTDSALERWRLGKKRSDDHLDDAEREREPAIVRSSSSFERNLEVWRQLWRVTEISQIILVLVDSRCPLLHFPPSLARYLSNHKVILVLTKVDITGPVRANAWIDYLRNSFPGLRVVQVQAYGTKEESFYHQGRSKYESRVPQIFKEQLLDAIRDLHAEILQPPKKIIENPDRLKSWKPPVKQEIDWNAALNHHAQRTMVVTDTSDPEEGSFLTIGLLGSPNVGKSSLLNALFGESKVRASKTPGKTKHFQTLLWTSEIRFVDCPGLVMPNYVPMEMQVLSGVLPISRVSAIPACVHYAAQLLPLEDIFNLPHPRSEEPPITDKRTWRENMERVENVSMYWTAMDILVSFANKKSWVTAKAGRPDFSRAGNAILRALAEGQVSWGFWPPGTPLFSIEPEDRDGLGHGVWIKQYNRKTSGGEDNNEVSEDDSDDDDDSFPEDSNDDDSNESELESDRWSGGDTKPINAGKYPPTTTRFAVLHIESDEGASELYDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VED2</accession>
    <name>A0ABQ8VED2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_920260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="40655" checksum="7D7DFFA103AB8BEE" modified="2025-10-08" version="1">MKSIIETLQTEHDSTLIELQATRTSLDTALSPLLAGTVSVPEAVTRYESLDPDTNADEEAVEESLDEFVSDTSLSDLTTTSIYGGHSINESFATGKFSSDVHGQDCREASRKFLDVESRFVEDMAAVSRLPGDVLQESDVYDKVMASAETESSEDKSLPILPETTGATILPSVSTSPALEAADSVSSWHISIKSLEPILSKLPVPSTGKAVKDLCQKAIGTEAEVNYCILKCPEALFTLSDTDSRNQTLVTVSKNAATPCKNLIKFDRHWRGHLLLQNGIAGHLYYLGEFESGTGHEVTPSEYKYSFPEETKAYVLSAGKSLRHNDIRAQEHLLQSMENGLHVTKTELRFIGYSKTIEHWLKVEGAQKGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEI1</accession>
    <name>A0ABQ8VEI1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_953339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="973" mass="109409" checksum="E2AAF4FC0CA152BE" modified="2025-10-08" version="1" fragment="single">RSRRRQQSENPAWFPWPDKETCILDILRHLPRSLFSDAQMDVILWGIASFGVSSAPSTDAAKSISEYLQTLCGIQTERQKGPLGHVYYINQLAGLIRQEMGNPKIRPHIRHYPEESGQHVEHAWQAEAWKTLDSDLALPMVRVGDQDFYVHELTKLNDGTLVMPFRWFTRSQGLPGGPEQEFFGLAWSVEVYPTSDGGGYVVHQHQTIQFPASQLLSSFPYLVETHDLDGIPNPCNILGTIITSNFSDIYLTKMYLYVYMSSHDHEIQPWSFTSAEHNFANRWRVLAKGHEVLNFSMWLYCDDTSGNVSKKWNKHNSFLFTAAGLPQEYGHQESNVHFLCTSNLAPPLEMLDGITTQLEQGQSEGIWVWDIQRKAMVLTIPAVLAMLGDNPMQSEFACHVGLAGKYFCRCCFVKGRDAEDEVLVPAQGSLRDDVSIQSDASDVGEEGGKKHGRRKETIQELVTRAKRFVGISETRHPKKTIETLRNIFITSQKYNGKTQAKKIVTQTGVKDTFLESFNQRIVAFTSKLPTNSSADQKQKLVDNFVAENIPSEPNIFSPIWRIKGLDPHRDTPVEILHVILLGFMKYYWQDAISRLSDPQKEVLIHRLSSMDVSSTGLSPLAEEMLVKYAKSLTGRDFRAIAQVAPFVLYDLVPKECFEAWLALSALIPLVWQPVIHHLDSYLATLELAIDRFLHCTANWMPRWFNKPKFHIIKHLPMHIRRFGPAILYATEGFESFNAVIRDHSVHSNHQAPSRDIGRGFAHCSRIRHLLHGGLFFSPSSEGATTPLTQSAFSDNADHWVSAGPLPLKLARTGLGNLQSPVARAYGLEHPEGEKMQPGMSDSVHRSCLSDMHGLSGRCIYSKAAKFNQPASEVLTLTKLPNAVSSADTQRFHLYEQAVSASLERYQVGHHVVVGASEVSPEQLCIGKVYEILQMSSGTATAVLLQLCELGPVDEAYKLQRIKPGEWTLVEAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEN5</accession>
    <name>A0ABQ8VEN5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ChrR-like cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_766443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="62" mass="6943" checksum="F86D95A5D309D882" modified="2025-10-08" version="1" fragment="single">ITHDYIEEVIFLEGGLKDLTLQQEWGPGAYAYRLPGMKHGPYRAGENGCLEFVRCISVTKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFC1</accession>
    <name>A0ABQ8VFC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_765666</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF19">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4492334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="85" mass="9497" checksum="7D51D9B672C023BC" modified="2025-10-08" version="1" fragment="single">IRPSKIVLAGDSAGGNLCSTALTVLCDMGMPLPARAILISPWVDLTHNFPSNMHNSKTVSSLVYLNRRPIHILRSRRTSYHYMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFI3</accession>
    <name>A0ABQ8VFI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="83" mass="9494" checksum="D18252AEC8E30EA2" modified="2025-10-08" version="1">MDEQFVFHDPPKKIAGFLSFPICFELLRGMAGCEHEVSGKWPCVGYTVDIDPVVGSLTSLIKKQSYDMMKWDPLEKWDGLEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG51</accession>
    <name>A0ABQ8VG51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein-tyrosine phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_951180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14522">
        <property type="entry name" value="DSP_STYX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="30"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="96"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4493235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="207" mass="23819" checksum="12162BDC40E23447" modified="2025-10-08" version="1">MFNGNLTEEQLKNVIQGPGDVEWKYEMRRECQEILPGLLLGPFVASKSLETLRSLNISHIVCIRDQKEAFSVKPRFPDQFMYLVLDVEDNEEQNLIRLFPSAKAFIDTAIANGGRVLVHCNGGISLSPSFVVMFVMQHYALSWEDALHMVQNRRYCISPNGGFLTQIKEYEAIYRANRAVSSYPAMPRNVSRRKRSDDDEEEENRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGG6</accession>
    <name>A0ABQ8VGG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_902727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="137" mass="15515" checksum="7A0DDD4CA0BC85BC" modified="2025-10-08" version="1">MHHWEPALMKIKHLQRILTRTEGEPTRYLWFNEGGGVADTHMKIGTPCHFRARAYGEGCDGRLTDLTPAKKRTNPRWVDASQNLAVANFNAVDHTGAPLPEALLPQTLNGATIDVTFTLRGWKFGRDTLVPMFQHYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGS4</accession>
    <name>A0ABQ8VGS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="44591" checksum="EA20C11193A699D9" modified="2025-10-08" version="1">MYKDPSVILLKRDSIFKRLESDLILAQSNAEIEFHLYPLLNRVVTDFCNVNEGDNRFTLECHPQAYFGDSAPGSYRLPDCAACTFDSRASTMKEAIKPIFWFEAKPLPDSRNWRKKEVLIDTMTSSYFAAAIPQVREQVKHAFRSFDGPTQYPVFILVGLYWSMLIFDKDKEQRAYEHEETVASQVLARQAVAANLLALKDRATSTASTTSVVDPGGAQEKSRFSSPERQIDVFDDYLPELKYFNEPLLLGTPVQEYNPAFLHALSTIMEKHEFSQQPSCFDVPHNYQYVPTINILANGMKRLRTVYRNILNSIMVNASMEREDEEYSQSEDSKDGSYKPPGRYNAPPHWVDNEESPIQTRARTKRDRRVISPLDSSPVEQQAPRGSGSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGY6</accession>
    <name>A0ABQ8VGY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_343265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056146">
        <property type="entry name" value="DUF7729"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460:SF1">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24855">
        <property type="entry name" value="DUF7729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7729" evidence="2">
        <location>
            <begin position="289"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="534" mass="56930" checksum="CD51583DBAFCAB0B" modified="2025-10-08" version="1">MFTPPASPLPSPRAKLGQVNPMGEIQRQSYVLLTPPSSGSTGPPRSGSPQHSRSSVSSPSYFSAGSSLDPPPSKGLLSKPSVATIPSSPSVSPSCSSTPSASPLYLPSLSAVPKTESIRPQRPDFEFQSSSEAKRRIGRRIKWTAIAIPAVLILVTLANHCFSELLGMVWWVNDETLEAHDGQNWLTPDTPNVIMDVLHPSHIHHNHVFQPVDNRKKEDTMNEGIFRRQESTDISISVATGTATASELVTPTSTAVSSTSGSATTTTSIPATSQTLPTIPDSAPVLPTPFPQPWDSSITQNFSTQSCYNFFLNMTNSDDFRSCRPFGLLQNTSDDFSDLQTNLTALNAVVWGTCNPTIGVDQCTTNMATFAASLQSACAQDLKDTNLYAVSTLQALNAYSLTQSAGCLNDPSTDSYCYVKAVHNTNPSDLYFYSLVSGVSISNSTTLTCSTCTKSLMSLYVNALNVNASQLMELASVYASAEALASSSCGSSYAQVSTNTQADSSNRASKSSSLSLNIFGTFLATLLPAFLFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHK1</accession>
    <name>A0ABQ8VHK1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_763822</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="4">
        <location>
            <begin position="50"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="401" mass="43634" checksum="CA7FDEC5F4ABAE0F" modified="2025-10-08" version="1">MSQVEVSADATKTKVAEEIKFDILAGVPAGGNELKRSQIARTFISQIALVPTKEMYEYALFASLGDDVYHEPSTVQVALEAHVAKITGKEAGLFMPSGTMSNQIGLRTHLMQPPYTILFIMIFYCRYEVGGAGFHSGAALTPVIPSNGHHLTRKDVENNIIYGPDVHFAPTEVIALENTLNGTIFPQDEIIAISEFARSKGIKMHLDGARIWHVAAETGTSLHELLEPFDTASLCFSKGLGAPIGSCLVGPKEYITRARRIRKLFGGGMRQTGILAGAAAYALTHNFPLLHRVHVLTIKLQKSFEDIGVTILSPAETCMIFYDAASIGSTYDEIAERGEALPEPLFLGGSRVVLHIQTSEAAVDDFIKLIATIAEEKRKAGFVNSAVQANGHQDVYVRRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHN0</accession>
    <name>A0ABQ8VHN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_920964</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="71"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="73"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4487433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="473" mass="52825" checksum="7416525D387EF5BA" modified="2025-10-08" version="1">MPPITRTRRESLRIEPDAVYAPDDDSTTPISAATTGSPITPLATSPDSAASESTEADNDGDAIIRSSSRRSREKRKRSRVTPEQLIHLERYFAVDRSPTAARRREISDLLGMQERQTQIWFQNRRAKAKMLDGKVKDRNVSRSPDTSSLKYDGDLHHIIHEDEAVTFIPCTDLSIGTWRRIATTVSKHDLVAYVCEAKQSLAWFILSGGTGFKMEIPFDRIIATEFNHTSPGIAHAVFTVSEPPYFYLEHRMAPRPDGRIKLSWRQCNDWTEGAQATHVLRHSLLGSAPQLSHLVQRLKLFRSHRNISLLSTPYKGDDSLPSPLEIPAPPMAGLLRHHLSPYSDGSPDTDINGDSDQVTCNSDGYNPHLRNAPVLTSAYGEEQYPRLFGRYSTPDISSYHQSSTGATLVAPVSRLSTARPYTVTQETFPSMYSDDVSIAQSLQSARRHTWTNVQDHVSPSLGTSFHPAADFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHT4</accession>
    <name>A0ABQ8VHT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_829408</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="659"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="669"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="826" mass="94244" checksum="47A45187937A2703" modified="2025-10-08" version="1">MFDEDTERVEHKKPRLPNACKNCRLKKVKCDSAIRPDNICSNCIASKTECTREPVKKRGPRMGNPQRSIQATVDAILSTRKPFEVPKDPAIVKGIFLDLANCIKDLEEDIARLRQTLSTPLSHENPLSKTSLQLNREERIAVVSRYPDHPSPPVEGYSVNDLTRDLRTFGYYEDRARHFGSSSSRKLVKDALDVKKEYTGGADFVNVKPSFKRLEFWSVQPWQKIKPEDPSPFEFPPDDLMTDLIQLYFTQFNPLLPLLHHPSFLRNVAEGLYHKDRHFGGLVLAVCALGARFSNDPRVVEDYTTSEQSIGWKWIRQIQPIRHSFTEPPSIYEIQLYTVYTIFMGATTTPEVCWILISTAIRLLQDVGAHRRRPGDSKSSWGTESWKRAFWFMYSIDILASTLLGRPRSMSQNDCDADLPIECDDEYWEHPDPKLAFQQPRGKPSTMSYWIHFLKLMNIADSTLHTILAVKQSDMWSAAFGLSKREWNEKTVSELDSLLNKWADEIPDHLKWDPSRENIQHFNESVVLYTTYYGIQILVHRSFIPRPGEDSHSTVPSLAICANAARSCLHVLEVEQQRKTNAFVIPSVMMALFNSAIVMLVNMWIGKHFVGSSPSGFSKDLAAVYRAINTLHRYELRWEQAGRLADILTEVISVSHFHKSSQPMSSMKRPREDDRNMHTHSSTDPDFVDNGQRHNDMIAGNDMGTPYLPTIEEHPRNFELPLNSGELGSLPIHEPFLDWSVPSNQWVSNSENENALDSWAATVPNDTNQFGFYNYSTSSESITNFPSTVSGEEPLDNRVPNDLDDWTSYIAAIDEILQAANPRVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK84</accession>
    <name>A0ABQ8VK84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_319207</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="808" mass="90946" checksum="29CCC432695F95E5" modified="2025-10-08" version="1">MQQKHDVVHGTAARVPLSAAAASSASTTPKPPSQPDKKKRRGGVAALSCAECRRLKLKCSRVFPCTGCVKKGCAAICPDGHLTTGKGNRFVLANINELQGKIEELTTRAKALEDALAKSHNLVSPQPHPLLSDDLLQITRTVKEESPEPNLSTDSTTVKKEENNKEEQDEALIVYKSSLGSLYAGEQSTFYGRSSTSWHFLLNETGASQQKEVPKGIIKRPLPNDLPWLANSFPFSTPVDGSTRQKLVGFLPTVAVARRHCQNYYRYGAWQYTPISEVEFKTTIFEPYYEPDEGTLFEDPLVSHNLAILFLVIALGALLDLEGQAHSQEAKWYYQLGKAALALEPVLDSSSLSTIQALILLAYYMLLDDIHDLRWSIMGLTSKLTQTAGLHIDGTHWNLPPEETYRRRCLFWEVYSYDILQSLTYGRPPHMALSFVDTKKPFETTRDANGDVEMTCDAWKHKFFSECLGVIWNKAFGAHPLSYDMLKHLDQQMRAYYVPPSLRVPGFGGAKLNQDIHPPSPELTMQRHFLVALKEITSFYMHRGFFIRAMNEKPENPVEHHPYGESVQTIYDSACICVGLMRSLFRQQPLIMQRFPYFFDHIFSCSYVLGSIASKPKVPIALSALTNLELAYDFFEAMADNSPRKSKFLAEAGKLREQARLALNVTQNPLTEAQKLARPKPIKTEEPVSGRQQSSWTKHVPFSLSSTLPSASPTSPSNHRYSPTAAIPPAFQTTYNLPQPTQYPVDHLFLTVIRFSINPIRRTTPFRAINITITKMRDTFSKRWITSQGMMPLVMLSCLYWKSRGRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKQ4</accession>
    <name>A0ABQ8VKQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_880155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4496968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="411" mass="46557" checksum="37D65CB27FEEF020" modified="2025-10-08" version="1">MSVELPFQISIPDFKLDLLRQKLALTEFPDELENTGWNYGAPLSDIKRLVARWKDGYDWKLEEAKLNQDLPQFTKDIEVNGFETLNIHYVHQESSLANAIPLLFVHGWPGSFIEVRKILPLLVQSSPQFPAFHVVALSLPGFGFSEGAHKPGFAAEQYAEVAHKLMLSLGYHEYVTQGGDWGYVITRIIAHRYGGKYSKAWHTNFPLATPLNISVNPILFLQHLFTPYTAAEKAGIERSKRFEKEGQGYFHEQSTKPQTLGYSLADSPVGLLAWIYEKLATWTDSYPWTDDEVLTWVTIFYFSRAGPAASIRIYYEFVHSANGSQPSSFKPMIPLGVSHFPEELRITPRKFVHSVGNLVFQVEHSTGGHFAAYECPDELVDDLRKMFGKRGPAFGVVPGKNGYERRIRANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL93</accession>
    <name>A0ABQ8VL93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_760239</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017348">
        <property type="entry name" value="PIM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF72">
        <property type="entry name" value="CAMK PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037993">
        <property type="entry name" value="STPK_Pim-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="52"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="390" mass="43694" checksum="76279CE06576C651" modified="2025-10-08" version="1">MSSPRHKAQHTFPAYKVNSPRTPAIDYNLDSSFHSHHFPPDHRLNPHFVRIYQLGDELGSGGYGFVVTAKHRIEGHEVAVKFIIKEKVPDYAWVNDERYGRLPTEVIILSNIEHDNIVKCLDIFEDAKYYYLVQELHGTPWHNPDHDKKLTAAENVQPTEPFPVPPLSPSVSADSISSLSPSTPSHTSSVIASHSSKHKLKAPRPPKFPRRPSHDLFECIEQSDNKCLSEDQARHVFAQIVDAVDYLDSIGVAHRDIKDENIVIDGNLKVKLIDFGSATFTDPAAEPRPFYNLFYGTTAYAASEILQKKVYQAAPAEVWTLGVLLSYLLTGTSPFPTAKDAVAGRIMIANGPRVSRQALNLMHVCLDPNPTTRVTIQEVKSHPWLTSRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLA1</accession>
    <name>A0ABQ8VLA1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6830 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_760421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049233">
        <property type="entry name" value="DUF6830"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20722">
        <property type="entry name" value="DUF6830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6830" evidence="1">
        <location>
            <begin position="264"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="562" mass="63762" checksum="1E537CF65CF45D7D" modified="2025-10-08" version="1">MFWDHDIKWAIQAVGATSIDFRFSIHQPTVGYRSFKEGVSTLKQVTGRTQRDIQRYLIPLISGAVTSQFVPALRALMDFRYAGQATRFNQVSASRVQAALDEFHENKDIIQHLKARVNPKGVPIVHWEIPKLEFMQSVEPSIRASGPIMQWTADTTEHAHITLVKDPARSGNNHDFEVQICRHLDRQARVRRFDLMTAMVDARVDFRLGNIEGDEGRGDEGGDSGKELLDEKEATTKISSSEQLAAHLNPVSKKLFGSFRPKRNFFLRARLLKQTPSAPLPLRIFSDEVSGEISAFSFVRDADLKTLTIEQVSILYALPDFRGACVDFLERYEAKIVSFVIGGRRGNSQLTLPFTKVRNWSRFRIQSKTYFNTDLLTDPHTIFAAPPSTDWEFGRQNAAIINIDPSFEWPRSSLEGHCVVLVKVLFTVSQPRKPSPPVRGTDQFLAYCERLDVVNQALPPHKYCHLSGYNSWPPYNPDYSSGCFILKRARRADGTPFGDVIPVSQFCSIADICPRYRGNPHPSLKQESSQYHSDEFLLNKYFNKELFFAIDKVDPSLTSSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLB8</accession>
    <name>A0ABQ8VLB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047206053" evidence="1">
        <location>
            <begin position="21"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="180" mass="19195" checksum="AEEDDEDCB0ED1632" modified="2025-10-08" version="1">MLAKILALITITSLLSFAAASPLPTAVDHADKVAESSALNITAPPLSGNIRRAPTNLVLNLVGCTMEIITWASFNPGRLTAKQDGILYGSIIPSGGLYLAVDPRDADTIGRASRCPGGTFVVVEYNFVSTGLRIVDMTAGQRYDETAHAVIGYFDPSRVGIFAPHMKMYVLQNPIGECRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLN3</accession>
    <name>A0ABQ8VLN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exocyst subunit Exo70 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_894690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="45428" checksum="84B1555E251462B5" modified="2025-10-08" version="1">MDNAANNDTTTTGLERLIPTFAGMLWRIRCILHILNLIAKVCIIIIIIIAYSSAILAHFTKQMKRKKSNNSTSTTATPEEEILNDDLAEAPAMQENEELDDIAIADEDEASAVLDAAQVVHDNGVIKTGVFIASNEQKRAEGIIPKVSGLARRVNDSSSVLKPEFERLVASTPELRTDKTALSRRVPTRWNSEYSCLCDHILLRKPVEQLTGQSQLKLSAYRLNALQWPLAKELRNLLKIFLDATNAFSRKETPLIGEAVELLEDIIHSLKTIRDSEFSPNGNLVSPIIRVAAHSGVLVAEKYFKLLNECEVYVIAMVMSPEKKLQWFSNCGWSQEKVAEITEHILGRWMQTYVSLPTTSASSASSTVPHAINPSSMSLGSWCNAPFYDIYEAIDALEKSMRREKVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLX6</accession>
    <name>A0ABQ8VLX6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_894608</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="538" mass="61234" checksum="E463CA173731543E" modified="2025-10-08" version="1">MARLPSEPHSWSSIPQTIANFPVQILATFLTVFAVNRIWVTLQKLRAVNHLPGPRPPFSPLGLPGVLFPTSWWNTSQDVHWARRSNLYTNNESVSIVPFLIGEPLIWTSNLNVARQIASGGNRTAFFKPPWSARALLLWGMNLFAAEGDTWRKHRRVMGPAFNNELYRLVWTQTMKTYRDMVTSEKWEGKASVSVPIIQELTFKLALLVLGTCAFGFSFRWDEPPRTSSGNLSIQETIRTVADSYMLRVFAPKWVLRIPLKMIQQSNAAYEAMALFMKEQVVVRKQEIQENTRKDAFSLLVKANEQEELKYQLSDDELVDIIGNIYIMLFAGHETTAHTLAATLGFLALNQDVQDEVFAQIKEVVGYRRDPEIEDYHNLNKVLAAFFEALRLFPSGHIMIREASEDTVLQIPSPRGQEGTIPFMIPKGQVVVVDMVGVQYNPRYYDDPASYKPSRWHGINNDSEDFTAFSVGPRACIGRKFATTEAVCFLSMLLRDWKVIPKLNVGETEEDWRARVLDAKLVLTLGVRDVPLIFVPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMC0</accession>
    <name>A0ABQ8VMC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_865324</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="138"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="63994" checksum="00ABF4402B6987DA" modified="2025-10-08" version="1">MSLAQPPLSKNADTRSSRKNGNALRRGKACINCRHLKIKCDGIKPICDLPSRANRLQSDIEELLARIEVLETSNGSSRKNVPTQSSSATSPSLSLSLSLDSPQSPQSSNLIQSIFSLDDDYSSSDSEPPVHERASLIDNFISRCATLAFFLNLETFRSSALLPLPLGDPQRPSPALLACVYLWGLRISSSPWKSAKGTAFLRRARRFIALEGVGARNRTQVMHLIQAKILLIIYLVHGGQFLEAEFHGNGAISLVLSYGLHKIIPASDGVYDDPEGRLPPCTGPVDQAERINAFWSVFYIQRLLAVIVNSPSNSFGSLDSYLEIQTPLPLHTENYGPEDTARTLYDFLHNTALQPPETSSLGIYSKSAILLHRAVYLHKQIDTGSSLIRGFTLRFLRTHIPGDRHKISEECTRLEKIVLNFYSSLPEISYIKELEARSSPFPPFICSEKLSLMYAVVGCACVNIQSIFSSFGVVHEARKRLVDASRNVYASLELTYPGSHPLAGTLSRLTCEAIVRELNSIKAGSSSASSWTGDVLDTARRVEEESQLVSTIIDGMGTMSILVTCCPLVGEKVDAVDSNNLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMF3</accession>
    <name>A0ABQ8VMF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_759120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="166" mass="18072" checksum="26DBF9ADD52FB868" modified="2025-10-08" version="1">MSFGIEPFTKDLNLPLLSGQEPEIVTAVLVPLPKDTNAVVFGQRIAMWPQRFNSYLLNSSEIVVDPQAVWDAPAENSQFAVTTIVPSGFAPDNRFLSVGPFSDDRYIAIVCSHKKAGQSHYAPSTPTFSSKHFNIEGHKALSFTMVNAEDGGDTDYHDTIVGVAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMW0</accession>
    <name>A0ABQ8VMW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methylcrotonoyl-CoA carboxylase</fullName>
            <ecNumber evidence="3">6.4.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-methylcrotonyl-CoA carboxylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_918045</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13589"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57344"/>
            <dbReference type="ChEBI" id="CHEBI:57346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855:SF13">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="8">
        <location>
            <begin position="47"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="9">
        <location>
            <begin position="304"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="534"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4496785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="562" mass="60342" checksum="9907C75A02C6C826" modified="2025-10-08" version="1">MFFKAGTRRALQKVGLQKCSKRLYHPTVLPSLISTTSPEFISKKEAMDDLIEELDAKTAKARLGGGATAQERMRSRGKLLPRERLALLLDPHTPFLELSSLAAEDVYSDYIPGAGLITGIGRVSGRECMVIVNDATVKGGSYYPLTVKKQLRAQEIAREHGLPCVYIVESGGAALPHQANVFPDREHFGRIFYNMAQMSALGIPQISSIHGISVAGGAYVPALADENVIVQNQGRIFLAGPPLVKAATGEEIDDESLGGGMMHSTESGVTDALARDDNEAIIRVRGIIGDLGQAGYRGVLPEEKVEGPVYSAEELHGIVGTDVRQPFDMRDVISRVVDGSRFREFKKDYGSSIVTGFAHIHGYPVGIIGNNGILFSPSALKATQFILLCSQRQIPLLFLVNVAGYMVGSKAEKGGIAKDGAKMVRAVACADVPKLTVIVGGSFGAGNYGMAGRAYSPRFLWMWPNAKIGVMGSGQLSQVMTSVSKDPSQHATLKSEIEHQSTALYSTARLWDDGIIKPTDTRDVVGLGLALASRRPSSGNQSRTGRSTTWDGNGMGFGVFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMX0</accession>
    <name>A0ABQ8VMX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_260447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045868470" evidence="2">
        <location>
            <begin position="20"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="202" mass="22405" checksum="5EC3B97682945B53" modified="2025-10-08" version="1">MRVFDILFPLITLTVRAAASSNSPPPSLLSDPNSYELSHVGAAPPSYSDMPHSPPPVYQPPPSYEHHREDPIYPPQSGDPNRPSSHLMQTYPNSVDHSMRNGTADLELGSLVRQVDYNRRFGQCVCAVIGLAMVGVIAGVTATSKHSRSLTDNHSNKKCDCPKANQTSNVNLEDVHSQEPTRCKRGAARMSYRRRIRNWNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN68</accession>
    <name>A0ABQ8VN68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_183726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046851746" description="Secreted protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9603" checksum="62996EF22768E6E2" modified="2025-10-08" version="1">MCCIMMLIVIRYLTSFMSFIISVVPCCYCSSKKQNLYTISCKIMYVVVEYPHIRILCNVGVCISINSAQRHYFLKFCPELTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNT1</accession>
    <name>A0ABQ8VNT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Csf1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_894171</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029636">
        <property type="entry name" value="Csf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048636">
        <property type="entry name" value="Csf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085:SF3">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21678">
        <property type="entry name" value="Csf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 N-terminal" evidence="3">
        <location>
            <begin position="20"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3072"/>
            <end position="3099"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="3213" mass="362121" checksum="5FE8526905C64047" modified="2025-10-08" version="1">MLNILLLIACICITIASFLYFFYFNRLIAWFIGLVIRLVYWNDGASSIWLEIGSIHFSILSGRILFKNVRYHSSNQTAKIVKGQVAWRYWIRRPTTEEEIGMSLGGGGKITPRDSSCRIQITLHGFEWFLYNRTAAYDNILAQMRSHHPVNSQRRTSLHKSSAASLVPSSLHTRTPIFLTNLVTWIRGQLPNLDPKDLLPLGIDINKGAIICGNPSTPNLLVAEFQHGSGTFGIVPSRSKYDLYKQMLTLKFKQALVQFVENEHYRDSMTSTGETIENQINNYDLRTPSTLASYHTFAKIWDSLKLYAPVLKYLSANPRRVMLPTSHLRRRANKKSLDEDTPLGIDFSKFEYAIERKILETSLLELCYYTDVVGLVPRASITQPSASDPFDIGNGDIGPEWGVDIAMNDGTLRYGPWADRQRGELQRTFFPPVYSDSQESQRLQPGDSRVWTAMRVFLELRGETTLHVPLRESSKNWQWDGVVKETERPRKREPAYLHLTAGDRSSISYLMPMVASKRGYEPILEVHLDTVTMTSSLNDIRLVSAESCRVHCELPSPLKWKAQRTWNVGVTLRRPTLYLIRDHINMFTDLGKDWSSGSPHDYQRFIPMIYQIQLDMHYYELNLYANDQNIIDKPLVEDENAIFTLAGVRFSFNTTIPSNVYRPESTTVPLSIDVPDVSLKLSLPRWNTNALHAPKKGNTLAKVGSFHMDGSYLYFADFHEEHVEQLVLTMKVRDIIFKSLGWSIRYFMILRDNYLGSFTHFSTLYEYLRRQKRGAPLGDPVNNMMQVELGINVLDGLIVLPVGLPGYEIGLDMPAAPPNSIGRCVVITMPELNLQLRLHDLYMEMTLNIGTISSSIEEQFPETLTYPEIKAKKAPAVLIVDGIDIVANRLFGPVPRTITYVCLWEIHVGGIKASLSAYQATVFQAAVRALGINFTDALNAPADQYQTGIYPDITFVKVSLETIEILWRAGCATAHVSVHKGLKFDYNDLAGQFHKKLTSIRLPHLSVKALLDYNASNTWLEAAEVVTDVFLDIYSSPTGWHEMSAAQADFVWEQDRPTGRVDQLVNMLKTTRSVPGIRKHLKNVYMPQPTIPRQNAYSRRHYEHHPRSDIGPIDDVVQSSESDGENPSGFADTIRAARPLFNSHTPDGKNEEESLSIGDESDNEDLTDHSDGEWSDSDNEPDSNARALKQYVHLVRHYILHRGDSPSLWEEGPFIPIRVNGTLENQFAYAKKHLNAERSNWTPFAFEPPDNSKNSITVKLSQYDGIDLKLTPLIVNVLEALQSDLESTHFSAEYLTDRWLSSYIGDFPDPSKPKVSSRTILDIHSESVALHVLHRLDVIENGPVHKKDYSGRFAYLIFTASNIQISGNMSVENRSLAARFARTDMDLTSVHSDGRASAKQPALSFSVLEFQTTLFKDDHEFSCAKLTAELSHLLPSLLISVVNAVEGDLPRLVRLQKRASESSSNVIRSTIYHILHSSSNELVIDPLSTIQPSFLVQVGLPQMLRVDPAFRFLFHLRDCLWRLREVNPSWDMDRTEAQKVTIDDVTPLLRDRLLALDPDAYHTSRLESLQPLFPFIKPATNRRKDETYFPFSYVSIKLNSVELKVVDSENRTSCQISLSDMFSGLRLRHHQLLDEEDEFRRLAASQTSLRSKSPDLVQRASVSIVLGDIQTTIYPYLINFVQEIIRAQKLNAGASSAKKLKRARFKPFNVVYIHAVLTIKRLRLRASAEKLTFEFGISELRHSSTVLIHHHSKTQSMNHSLLFTEMFIKARATSEPHEHDDLASLTIADSLLSSVMRNETLDQSMKLAFNLKALRFSVPRSALRLYHFVEQWRADFLLGIESTVQALMLEVNKPSTKNARLPQSHSTFPKSSTLQIDGQVSCAGIYLRVMHDTWLSWEVNDISLFLNSLARAHQKSHEIGLQLSSQLFAVSTESLEPSYKTRVKFEFPPTLLSGHIDQSSIRITSFIHFLELKVKPSYWDTLLAVQQKFGQDFNDLLAVIQQTRSKRFPAPPASLSKPETTTQTDFSVFVQMEGFRIGFEGRSSVLYLECPGIRSKFEGVPEKVWSIIVTDLALSLAPRSSMTPHSFGLNRHQRSAFVIIDFKIQSESQGSGSEALEVVVTKIHAVMQPSSIGEMGDFIDELQEEMIDRREQRTQELAAFKQKTQRLIKTFEIKNQEPALSDRMSWLDNYIIQFSLSNIGVAFPLAHDHDMDLPPLGTHDSTAVRAFLFSIKSVKFGTQRGETGEAGMESLSFQFVPRFRQSVPTDFLGETHDTRNRLLYPTMTAQLRSSKSAMFSQIYMTATVSGFVLNMDSTIPDYVFSLFDVYRHGKERVQRLSANIPRGGPSIPNAAASSRQSSHSATAPDIFASLTFQSGKVCMFSTDASKSSRIRAYSGTWDRPEEPIGDVGAEVFNLPVVSVWAEYRAAPPSRQGSNAETEPSILIFKSTVHSSHNTLRPMLLPFVTEVVTLVEARLRTSTRIDLPSLAVEPAVQTEVTPVPNATSTLRMSFSLRIDQSRLELTCLPDVNVVAGVNWDSGGFMVNVLPGSRDVTFTGVVGGLTIGLKHGFLSEDCLKLDARNLAFSVALGKPCFEDRPMLTSISLVVDTEFLGAVRFSRLQDILCFKAVWLDRIPVFNTHNDDDDFSKTNLNHTPPTTLNNKSEFDIAILVRIRRIKLEVDLGQSISTVTLHLENSNLRTKLTQSFHELSIRVGHLAITAKGNVAGYANVPNCVFQTIQWVGKPPTEDGTRDRMLELRMMSGPLIVMLESDYQKLLHYRAEPLEVDILDDWSIPKSSQTDRPLRLSLTVKSKEVVAIATVGTIPKLLAYANKFKANLEAQREGASRESNTFRISRAPKPDNPLSAVAEAMITSARTRFKEADAILSYTIRQHMSLRLDLLRLVVFPRTMGDAEVAQFVGQDVRGRLNRLIESASTSSNRDIRLSFSFMRISRFTQLGHAIMPPITEISDGRQWLEDLLKDANNADIVGLPSMIMHMASTESQEGFHKTLAYNFDSQFVRLKGVQHSEDIYITLNVGLYSWLTVLRKTLSREMEQVQTAADWRMFAANPVQTRKNIPESLNLSNPPRSATVPSPTNAFSPLSPKSASAVTTNFGSSLDVASLSKSQPDAFAPSPTDGEGEAKAFVYQPGHRRIERLTMRQLGEATPDVMHPFFMKKAGFSLEDSLPQYVHEYATVPLEEIMEVLLRLYSRQLLAATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNY2</accession>
    <name>A0ABQ8VNY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_823472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="38283" checksum="A2EA3E097073C666" modified="2025-10-08" version="1">MSLENRVQKALVLESPKTPFVLKTVPIPKPGPGEVLVKIIASGLNPVDWFIQSRDLFAPNTPYPAIIGLDMAGDVEEVGEGVKEISRGDRVFLEPKLNSNEYASHQKYALAPVEFLGKIPENLSYGQAACIPLTFSTAVYGLLPAHPVGMGLNPTFDDTVTYPSEVALVIGGSTSVGQYAIQILKYLGFGTIIVYASTKHTEYLKSLGATHFIDRNEISFADLPAALPKVCSQPIKIIYTAVTSPEAQNAAYACLADDGKLAIATPRLVSWGDAEITTKKVYGVFGGPHIPPNREFGITLWKHLPRLLERGVFVPNRIEEIPNGLSGVVDGVKKYEKGEVNGVKLIVFPQDTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPJ9</accession>
    <name>A0ABQ8VPJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID 23-30kDa subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_894061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07982">
        <property type="entry name" value="HFD_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003923">
        <property type="entry name" value="TAF10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03540">
        <property type="entry name" value="TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01443">
        <property type="entry name" value="TFIID30KDSUB"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="169" mass="18258" checksum="2D568D99119104A9" modified="2025-10-08" version="1">MSDSTPVPYPLSSDIGQPVTSASPAPVAGSSTVGANGPGSSQSRQAAEDARKDRTLAEFMLMLDDYEPLIPNEVTDYYLQKVGFECEDPRLKRLLSLAAQKFVSDIAADAFQHARIRTNAAGGRARANQPLYGGPGSLKDRTRTTLTMDDLSAALQEYGINARKPDYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPZ2</accession>
    <name>A0ABQ8VPZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_757007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF177">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER MCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="1"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="436" mass="46323" checksum="257575BFD824DEC3" modified="2025-10-08" version="1">MVIPVQLHKPRDGLLDSTGSGSSRSEGPVGGQGTDSQLDCPDGGLRAWLVVLGVSPRVSSSLGYITSWGVFQSYYEQTLLKDHTPSSIAWIGSLQVCLVFLPGLISGRLFDLGIFKLPFVAASALLVTSTFLVAECTQYWQFVLCQGLATGLGVGMVFGPSLSVLGHWFKRKRGAAMGLTTLGSSVGGTVFPIATRTLIPAVGFPWTMRILAFILLFSLCIPCFTLARRLPPKAVSGGLFNFRAFKDSPPFTIYCVGVVFLFLGLFTVMTYIDISAVTNGVSPDYSFYLVSIVNASSLLGRVVSGILVDKTGAINFIAPTTFLAGIVTFAWPFATSKSSLTAIAVTYGFTSGTIIPGLAIPVFLLGDVSDIGRRTGMMMTLGALGGLFGAPISGAINRSSGGFKEVGYFAGTMMIFAGIFMLATRYLVLRKLRGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ99</accession>
    <name>A0ABQ8VQ99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_137677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="176" mass="20181" checksum="3971F01AE9CB98AD" modified="2025-10-08" version="1">MPIPFVFVSVFCVVYRCGDFPYTLQQCFYCYLYRAIDITKQQARMNIPLLSVITSIEYSTRHSRRTSHLAWGDVAVENPFGKHFVHAWGLRTFRTLQRGQLRPIIYYEITISSHWAFGFIDAGLDNGMHIYMSSREERGWEVLAGMPVPHILPKITPPPPPGLFRRDRSGKGDAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQD4</accession>
    <name>A0ABQ8VQD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_756459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="25352" checksum="77FF48C7F439BBF9" modified="2025-10-08" version="1" fragment="single">MRRQKIDSQVASRIPEDIHTIVDHYDLDPTLHISIACPNCYALFPFTNEAISNSETALRANQALPVCNKRSHPDLPPCGATLWRTRCIGTRTFVTPIRKQAFQDLQEWIGRILAIPGLEDIIDQHQQRPLPTVEFLERDFVDSSTFRCFKGADGQPYATPQMGPSGSPDLRLVMSLGFDAFNPFFLKEQHASFSSTALYMVILSLPEHLRYQPKYMYLVTIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQH7</accession>
    <name>A0ABQ8VQH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_865045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="302" mass="33152" checksum="29C097C8FD98151F" modified="2025-10-08" version="1">MSPLGPDGDANHLYSTTTYMDLGFHFLRPLLFASLLTAGQRVFHSAMQNLHYILKLILISSLSIGVRSAPYGAKDIGISVNPCSSSSGSEIPPVDSIHQRGLPSDQLPPHRRGVERTFRELVDDGTLVHFMTPTVLNGEADKNVFDETLKGITFGQKIERGLNNGGIWEISVTSEGPQPHWLQGQPKHGKLLAKFSKEKGPPQLPFAEVKALRMMGLLVAAGKIPYPHSDGTPLLRPAIIMEKKEGVSLGDTNVFKSAPFEEQGPMMKHVLELMCRQVAQDAIEHKVFHLSVPPSLYLLKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRX5</accession>
    <name>A0ABQ8VRX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="3 10">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Gamma-ECS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 10">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_757802</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glutamate--cysteine ligase type 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="3 10"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004308">
        <property type="entry name" value="GCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164:SF0">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03074">
        <property type="entry name" value="GCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="508"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="508"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="676" mass="76594" checksum="56779049AE5D5B41" modified="2025-10-08" version="1">MGLLSAGTPLSWDDTKKVADHIRSHGITQFLHIWDRLKDKNGDELLWGDEIEYMVVVLDNKTKNAKLSLRQTEILTKLNSIVNNLSLETEDSIAIPTFHPEYGRYMLESTPGSPFTGSITDLLSVEKNMRYRRTLARKYLKPNEIPLTLTSFPRLGSPGQFTEPYHDPHGAVSSHSLFLPEQITNPHARFPTLTANIRRRRGSKVAINLPIFIDEKTPRPFIDPTIPWDRSIYAEDPEAKNGAALPDHIYMDAMGFGMGCCCLQLTYQACNVSDARRLYDGLIPIGPIMLALTAGSPIWRGFLSDVDCRWNVVAGSVDDRTVEERGLKPLEHDRFKIPKSRYDSVDLYISEHWRNRPEYNDQPVVIDPCIYNRLRQHGLDDLLSKHIAHLFIRDPLVVFSETIDQDDKESSDHFENIQSTNWQTLRFKPPPPKSPIGWRVEFRSMEVQMTDYENAAYAVFITLLSRAILSFNLNFYIPISKVDENMSRAQGRGASQSEKFYFRKDVCPGGRSPKSSGSSSPVDESRPKDRKMRNCFPPPEIPENGVPQGPVEEEYSEMTIHEIINGKGDSYPGLLGLIWAYIDTLDVSQQELSKIHSYLDLIRRRANAGSLLTPATWVRNFVRTHPAYAHDSVVTQEINYDLIVAVDEIERGVRNVSDLLPEDYTGGEADGGSTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSD7</accession>
    <name>A0ABQ8VSD7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_815133</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17950">
        <property type="entry name" value="DEADc_DDX39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="78"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="265"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="430" mass="48336" checksum="5B2A4E149D7E8474" modified="2025-10-08" version="1">MSAPDNEDLIDYEDDIPIPAATSNGAVNGAADGDDKDKKNFSGIHSTGFRDFLLKPELLRAISDLGFEHPSEVQQECIPQAVLGMDVLCQAKSGHGKTAVFVLATLQQLEPINGQVSVLVLCHTRELAFQIKNEYTRFAKYMPDVRISTFYGGTPVSKDAEVLRDKAKCPHIVVATPGRLNALARDKVLDAKNVKHFVLDECDKMLEQLDMRRDVQEIFRATPHHKQVMMFSATLAKEIRATCKKFMSNPLEIFVDDETKLTLHGLQQHYVKLEEKEKNRKINDLLDTLEFNQVVIFVKSVARAIELDKLLVACNFPSISIHSGLQQEERIKRYTAFKAFEKRILVATDIFGRGIDVERVNIVINYDCPPDADSYLHRVGRAGRFGTKGLATTFVSTDEDQNVMNQIQARFEVAIPELPEHIDPASYMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSI3</accession>
    <name>A0ABQ8VSI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_939082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="249" mass="27966" checksum="80BF5FDE74813952" modified="2025-10-08" version="1">MEPSVPERVELSPAFEDVPMNDLVELIADMLERLMSHNDRIPLRPENLTQFHSQSAPAISVLDYLKRIVRFTKVEKSCLLITLHYIDQICARVPLFILSSLTCHRFIIAAVTVSSKGLCDVFCNNALYAKVGGISVGELNTLEREFLRMIEWTITCTRELLQEYYINLVRTHSTSKYIIAGTHSSEGSSSSGSSDFDMETLPSRSPSINEPSAILIEPVAPNTDVPRRPTIEQNMAFAALQYQNREAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSQ1</accession>
    <name>A0ABQ8VSQ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_136798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="193" mass="21850" checksum="D31202F7C21FEE58" modified="2025-10-08" version="1">MYVHTYYHNNLPGVTSLPHDSLPPAAPERLETLGWNLWMLSGDDIEKQAAEIAEQVGYTRPTDKINVLATETIESAGTVEEKVKMTAKLQASKEHYTATTSSVVLIVDGKGHYDIEDPIENMWIRVILTPGVLMHIPGGAHTRITFENPEGYLDVLMWFNKDVKHSDIDWVKGKDTQNHFVRLDYLNRLGVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSV2</accession>
    <name>A0ABQ8VSV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_875964</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="141"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="143"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="252" mass="28880" checksum="EC6C678B6092BDEC" modified="2025-10-08" version="1">MSSTPQSFLATPSPSDADNIHQLNPLELLAQVAADSQRLDTPLRTHTPNATPHEPRTPARSSKRLSSRRSASLTPSDSDFSTASRCSMSPTPTLVDRSDGSPVSWKARKTCHRSPKVTEAQKCARAAKEPRRKEVLARALRIRTVDNSPVNEQQYRVLRMVYDEITKYPKDHWIAIVAVIIHRSFAQVKHWFSNERQKNKSGETMDWHNELGEKIRVRPMAIELCEQWSDEFFENVVMVYNFKSLKLLQWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTD2</accession>
    <name>A0ABQ8VTD2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_863951</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032440">
        <property type="entry name" value="Ribosomal_uS17_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF484">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Z1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16205">
        <property type="entry name" value="Ribosomal_S17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="408"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="143"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="608" mass="67407" checksum="DA0F87DE82162CD2" modified="2025-10-08" version="1">MLQYDGTETVLIATQTQIEKAFQKQPLFQNAKVKAGKKVSTKDRRWYKDVGLGFKTPAEAINGTYIDKKCPFTGEVSIRGRILTGKVVSTKMNRTLIIRRDYLHYIPKYNRYEKRHKNLAAHVSPAFRVETGDTVTVVFTSRLSKGRPSSPQPAASQSQTAQQSSKKSKKTSKDKESESSPDNVSLDTSPDDSLETSDPKPSNGTPAINVPEPSRSSAQPLNGVHGSPYPNPSSIDPSSLTSVSPQPSPKPLPAPIDIPAAQTILSNANASAFSPGSTTTSTAQDMNGKLKPLDVDDMIQRLLDVGYTGKVSKSLCLKNTEITSICLAARDVFLSQPTLVELSPPVKIVGDVHGQYSDLIRLFEMCGFPPAANYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKTWKTFIDVFNCLPIAAIVASKIFCVHGGLSPSLHSMEDIKRIQRPTDVPDYGLLNDLLWSDPSDTALDWEDNERGVSYCFGKGIINEFLVRYDMDLICRAHMVVEDGYEFWNDRTLVTVFSAPNYCGEFDNYGACMSVSEDLLCAFELLKPLDGAALRKEMTKAKRKSVMNTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTX4</accession>
    <name>A0ABQ8VTX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_754278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="747" mass="82297" checksum="67D47328981E7AE3" modified="2025-10-08" version="1">MKSPLILRDPEVTQKLLEAMIDTPGGKRTVSRLARTCRAISEPALDVLWRDLDSLIPIIGLFPATLLKKVRKPGLGLSKEPAEQDWTKILRYGERVRSVLYNETANNVSPSIFLTLAQNRPREYMLPNLLHLSWKVETLIALDHCAMFLNPTIKSLQFELGTTRFPNLNKILGDACSRLNLTSFSIISPASLPDTFTVMLSSQKLLQKVALVAPGALSSGVGRWIAFLPELKSLQLDLSARTLTAVEGFFDELPSQSGDSTPNSVATTDSGVFSGEELDFSEIRLKSAMRGSKAGFSSLRHIHLTGDVANIAVFLRHFSIPLTQLDLVIEDPPDNAEWMELSYLISERFGSSLHSLRISATATSKFNDLVRSTSRGESTVSRLAFDNLQPLPALRRLDIDLPESINFLGDDIEALAHACPNLEELKLCPLARFPVQSGPPKLTLEQLALLAEHCRRLHSLSIPVNARRASPSVLDSQSNSSNSIRRLHVGHSWINDSLHVSILLSHLAPYLDNLKWFHDKNRPGFIESNARGWEKVADTLPHLQGIRLTERKAMVGPLPSLDIISAPPLPQPAPVDTVEKGIMASVSLVHEGVLARPLMTSRRPSMVDESVEVHPELASVSIDAAPRTTEIAVEAVVAVSDEFVEARPETVTVSVDARPPSVSKSVEAMILNPLEGKKSIFHSSSHSSLFPVFSLISFTYRVLVAYPISIPIRMLHVIFDNMPTIIRRPPASTNSDISMDSLQVRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUG4</accession>
    <name>A0ABQ8VUG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_32055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="220" mass="25470" checksum="8DBFD4FDA9201920" modified="2025-10-08" version="1">MRLLLPSPYRLYIASFLLVIALLNVAVVSRPVATSCLKIERRGKFTCLKESVRWPILYLVSDALPEDYQIYLARWHPARKEYVSKDAAFDEIQVVRFFMEGTVPDHRAGFEFVATPNGNKIERVEYPSSFGQRSFESIMLRVDQVQLGNFACVDSMFNIEFLQGVIDKLIISDLDFIWTILRSIGLSHSPAWRELCGNMNRARAAWNERHRHFYTSQSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW22</accession>
    <name>A0ABQ8VW22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_742444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="16536" checksum="B41CB2AD026044AB" modified="2025-10-08" version="1" fragment="single">SISGEKRIRNRAYQEQSVSGTTRIRSKAYQEQSVSGAKRIRRKAYQEQSVSGAERIWNNAYQEQSVSGEKRIRNRAYQEQSVSGTTRIRSKAYQEQSVSGAKRIRSKAYQEQSVSGAKCIRSKAYQEQSISGAKRIRSKAYQECI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWT2</accession>
    <name>A0ABQ8VWT2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar protein sorting/targeting protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_356903</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031777">
        <property type="entry name" value="Sortilin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031778">
        <property type="entry name" value="Sortilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006581">
        <property type="entry name" value="VPS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050310">
        <property type="entry name" value="VPS10-sortilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106">
        <property type="entry name" value="SORTILIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106:SF27">
        <property type="entry name" value="SORTILIN-RELATED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15902">
        <property type="entry name" value="Sortilin-Vps10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15901">
        <property type="entry name" value="Sortilin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00602">
        <property type="entry name" value="VPS10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045552472" evidence="6">
        <location>
            <begin position="24"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1348"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1390"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="7">
        <location>
            <begin position="48"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="7">
        <location>
            <begin position="712"/>
            <end position="1344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1453" mass="163506" checksum="1433736E5480BCEA" modified="2025-10-08" version="1">MILRALCLSLVATLSLLNVQVVAQDPTHEITSFENLPAKLVFLEDTTTAFYLDDLEGILYVSQDEGKSWNAAENIPAGEATMVIEHPFEKNYAFVLTQGYIHYRTEDRGKTWRPFEVPVRPAFVAQPLSFHSDPKKYGYILYQGTSCDQVGWGTVCHDETYYTTEAFTDDAKLLLTETTRCQFAHSTVDFKHEAHSDLIYCVAFDTLEGMHSLSHSRLYSTTTFFDEDMTVEDLGIGSKNAKGVFAFAIVAKYAVVALKDMSADNNGEMLLYVSVDTKTWAKAQFPHASSARLRENAYTIVESTTHSLAVDVVLQDQGTIGTLFVSNSNGTFFVQSLKDTNRNDMGFVDFEKLFGIDGVGIANVVANAEQVEGRGASKLLKSVMTFDDGSNWSPIKPPSYESSGAQVNCNPGDDDCGLHLWSVTAPHNFGRIFSSPAPGIVMGVGSIGKTLLPYEDCDTFLSTDAGLTWKMITKDAHKYEFGDSGSVIIAINDEDGVDNIIYSLDMGVTWKSYNLGLKLRARALSTVPDSTSQKFILVGQVSRKDENYNQYGRYVVVFLDFAGIRNRKCEKDDFENWYARSGKSECLMGHKQWYRRRKSSADCYVGDKFIDPVQHEDNCQCTDADYECDFNFVRDGDNCVPVGPEPIAAGVCTLPSQKYMGSSGWRKIPGNTCTGGHKDDKVEKDCSNGEVIHQTFEFPSQIVQHAYFRDHPTILVRLHDNSIWKSSNEGYTWSQFAPDEKFLAFYHHPYSSDRAYLITPESYFYSTTDAGRSWNKWNAPAPPNTFRAQVLRFQPEADRLIWTGNVKCNTGLFEDCHATAWYSRDHGRNWKQIEEYVVNCAWASDTKLNADPTEILCESYQRKEGNQRFFLQDNPLELIEGQGYYSKKKKLFNQVVGFAKFSEFLVVAELASSGRALELQVSLDGVNFATGEFPPSMHPETHAYTVLESSTGSLFIHMTMSEPPSPYWGTILKSNSNGTYFIVSQELVNRDERGYVDFEKVIGLDGIALINIVANPFDAMLSGRKLIASRITHNDGSTWKPLTPPTVDSEGNSYWCDYTACSLHVHGYTERRDPRATYSSPSIVGLIMAVGNVGEELAPYTDSDTFLSRDAGFTWEEVHKDAHLWEFGDSGSILIMANDEEPTDHVLFSTDEGAKWREYKFTNDKIRVTAIVTVPSDNSRRFILMGQYPSRQTESVVVHIDFSALTGRKCVLKVEDPSHDDFELWSPSEDRNELCLFGRQTLYHRRIRDTNCYIGDQRKEEARIQKNCACSTVDFECEFNYIKNANDECVLAPGTTPLSDDETCRAGEEFWYERTPYRKITYSTCDGGHRPDRGKAHPCPGFKHHSGWFWWFVILISFGLAGLVGLYFYRRSGIARGNIRLPTDARSSRLAGDDGVLSTLASVPWFLVGLAGIAWEFVASNVESLSNSYRARRGYRNLPVDEDAQILRFEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWZ1</accession>
    <name>A0ABQ8VWZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pectin lyase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_913967</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF19">
        <property type="entry name" value="PECTIN LYASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="370" mass="39308" checksum="CCC24B985A5910E5" modified="2025-10-08" version="1">MSSTTASTVPQSRYNRSAYPQFQGAVADNSTDLGPALTKAWQECVIPQVTTTVATNVLLYVPAGNYLLASTVTFDDAANWNLHIAGDIFLPFNPSLTGTMLTFENCENILLDGPGAIYGNGYRYRPGGDLSLYPSRPRLIRFQNCNDCEITAVTLYDAPMFHVTVIGNNNEAHDMSIIASHIGETDGFDMSGNNNYVHDVTVENGDECVTVKTPTNGFVGERITCRYTAGCNIGSFGSGTTGVDVQNVYYSDVTISNSDAGVMIKSYPNCAGTVRNITYTGFTLSAAACPIYISAFWEGGTTDTGTLEVSDVTFENFQGSGTPTRPAVLLDCNKATPCNDISFSGITISNAKANSFTNACGSGLSGLSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXD6</accession>
    <name>A0ABQ8VXD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_279486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="236" mass="26487" checksum="B6B7FCABB42B4251" modified="2025-10-08" version="1">MKRMCPIDRDVQIVRYLFQTLLPLELVDVIIEDAEYWPCIHVERSEPILVDAKRSISRGLKMAWCYLVSSPVPEALDSAGQSLGQSRVRRVDLKVQGHDQGWATHPGPWSWFEATIIKALSEPNLVWLPAALNGPVDPASVLAGLNFDQTFEGFTRWHIAANAIATQVKQDHSIVWTEQEAQAPGNVKGMRGREGLGHELVRALQPGDRIAILALAEQWGWENHVYNASIDIYYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXR5</accession>
    <name>A0ABQ8VXR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_806243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="161" mass="18355" checksum="CF6350086692A963" modified="2025-10-08" version="1">MLFKASYLSIFASFLLATYVAPSHSLAIVYIKFYFQNPDIAPPGTGSSSPQVRETVKFVTDVLRLKNGAKAKWKPQYRNRLDHDEDELSFYYWGDGVGHDCKREESSCFATGTQHGDQWHFEIYGSTNALLHHFSIPSFSSQHPQRPVHDIDHLDLHGIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYK5</accession>
    <name>A0ABQ8VYK5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_786116</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24134">
        <property type="entry name" value="ASKHA_NBD_OSGEPL1_QRI7_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="7">
        <location>
            <begin position="46"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="391" mass="42660" checksum="EDF4DEFE29EBA6AE" modified="2025-10-08" version="1">MLTSFRSFPFRKSAHLSRRLNRLFTVLAFESSADDTCVAVVTSDRQILSNIVVRQNDLVERFGGINPGAAVMAHQANLPIAAKRAMTEAKIDISDVHGIAFTRGPGMGVCLSTTLNAAKTLAAVFDKPLVGVHHMQAHALTALLTTPTHKPNGEINPAYPRFPYLTLLVSGGHTQIVLAKSVKSFRIMATTLDESIGRTIDKVSRILQIEWANMSPGSALEKFCLRPEKGILPDIFIPFTPVMPGRLAFSYSAVHSHVDRLLALNGGIENFTSANKLAVARIFQNAAFSQLEEKIKLALGDCEKQGIKINHIVVSGGVASNALLRERLRACVTVSPTNSSVETVFPPIQLCTDNAAMVGWASMHRFLAGDYDEYTINPRPKWSLEDLENDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYV2</accession>
    <name>A0ABQ8VYV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adaptin N terminal region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_748996</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026740">
        <property type="entry name" value="AP3_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037096">
        <property type="entry name" value="AP3_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="52"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="661"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="725"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="675"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="699"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="733"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="801" mass="88944" checksum="4F733A384F1C98CB" modified="2025-10-08" version="1">MSVDYLNTITENASRLGMRIQESLSEHTREMNLARSNVSYLEADDSKGRNIRKQLDSSSDREKLDSMKRLIALISKGRNVSEYFAQVVKNVASQNLEIRKLVYIYVLRYAEQEPDLALLSINTFQKDLNDSNPFIRAMALRVLSGIRVPMVGNIVVLAIKKCAADFSPYVRKVAALAIPKCYQLDDSHLPSLIETITKMLNDTSPLSIGSVAVAFEAVCPTRLDLIHQRYRRMCKLLVEVDEWGQIDLLNLLLRYARTMLPRPIVNSDGEEVDHDIELLLSSAEPLLQSRNPAVVLAVVRVFWYAGPPSVHVKVVRPLLRLLHISKEVERVTLSYILVLARINASLFSPHYVHFFMLSDDSRQAKAEKIQLLVCLVNFENHQPIFRELIEYTEDPNDQVVADCIAAIGKCAKMVPESMQTCLAALTEMINNNHDVVVSNAILVLKYLVQTQLSQISGANAVNPSQSSLSIVSSLARKIDHIRHPQARACVVWLVGQYCASDQVTSAPTGIAEWAPDVLRKTAKTFPKEDVLVKLQIITLAAKLLVLNPAEQTLGLIVRYVFSLARYDLNYDVRDRARVLSSLLAGVGSPVLTPEDGITPFEDRGGVVLRSEQVKVVLFNGKTNATDDEHAEHSNMIIGALGVIVGKTTLSDTILPDWHEEGVESTLRDSPDDTPVSHASNVLSVSSSTGSATPVLHPSRGNSPSAGLSTTNGRKWASNLDDFFKEDVGSDNEASSEYENDDSDEEYEDQAEGEDEEDEHDEQEGQSDENNDEEENSEEGNEEDRNSEGNLKNNETGYEAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ70</accession>
    <name>A0ABQ8VZ70_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">trans-L-3-hydroxyproline dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_809334</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10320"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:39785"/>
            <dbReference type="ChEBI" id="CHEBI:57938"/>
            <dbReference type="EC" id="4.2.1.77"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the proline racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.77" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442:SF1">
        <property type="entry name" value="TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="399" mass="44079" checksum="2B69FF64CCAB4DB2" modified="2025-10-08" version="1">MDVLQEIGEHPSMVRTVELHTSGEPTRIIVSGFPTLKGETLLEKRRYVSENSATDAVRKWLMLEPRGHEGMYGAILVQDTELTLSGEADIGVLFCHNEGYSTMCGHATIALGRFLVDTHDSEVFPRRSLLQVQKDDDGQTFTVLRLHAPCGVVTVNVPTTLEDKSDATKPVRFQSVTCFVSSPKQGVTVEVPLEMAWPKLIKQNKRQIRMDISYGGAFYALVSSAELGFASLRGSNSEFKELAEAARILRILLNQNSQARRSFVHPNEPDIGFLYGMTVIDSSISRNGASDQDEKTVTWICFFADEQIDRSPTGSCVSAHVPLAVDQTQLRIGEWCTYQSFISVQFAGNAFRGRAVTHTEMGYVVEIEGFAHYTGTANFIPPQKMMDAIGSGFALKLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W196</accession>
    <name>A0ABQ8W196_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="9">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Biosynthesis of nicotinic acid protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA4</name>
        <name evidence="12" type="ORF">C8R41DRAFT_898838</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-kynurenine + NADPH + O2 + H(+) = 3-hydroxy-L-kynurenine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF2">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0274">FAD</keyword>
    <keyword evidence="2 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="11">
        <location>
            <begin position="13"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="501" mass="57043" checksum="F58839EBB49C12A0" modified="2025-10-08" version="1">MTPQAIPARRRRAVVVGAGPVGCLAALMLAKRGWEVSLYEARPDPRLSSAKAASQQRSINLAISHRGISAIQAIDGSMAQRFMQTAIPMKGRMIHQLDGKWNSQLYDRDGQCINSIDRALLSEYFVNEVSASENIRVFFQHKVLAVDFDCRNITIEDTNNALTTTPSFDFCVGADGSYSVVRRQLMRVVRMNYQQEYIKHEYMELKMPASQDDEGCMKFALDPNHLHIWPRHSYMLIALPNKDCTFTCTLFAPSEELDRLNTPDIFLNWFRLNFPDALQEIGEKNLIHDFTHNPRSSLICTKLNPYHYKDRAILLGDAAHSMVPFYGQGLNCGLEDVRILNILFNQESAMSTASELLTDQEDEQMKRVLSRYSQERHKDLLAINELAMDNYVEMRHLVTTPIYLARKALDNLLYKISSPQYRSLSSLIPLLSDELYSENEPRGWLPLYTLVTFRPDVSYDTVRRTVARQSAILTGVGFVGAAMLLGLAGVWMSYATKSRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1I3</accession>
    <name>A0ABQ8W1I3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trehalase</fullName>
            <ecNumber evidence="3">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_907520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="4">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="775" mass="88336" checksum="F05F8DCBAA531236" modified="2025-10-08" version="1">MAPSLTHPTTVNFIEEHDLSTPSLPMKEAADYYGKSETFTRSRTYSASHIHGYNPRRIPAFDESTHARARRLSHDEKASQPRRFLIDVEETIRLVLEQEDTDGDFQISVTDAGPKVMALGTATSNGFKTFDIRGTYMLSNLLQELALARDHGRKRIVLDEARLTENPVDRLSRMIKNSFWHSLTRRIDGEGLEIICADPKNRTGRVNPRIYVPHGEPAMADYYRKVAREKPHLNLDVQVLPVKPDDPSFVKSLNNKPGILALAMNESDDGRGGKILKGIPFIVPGARFNELYNWDSYFISLGLLVDGKVTMAQGMVDHFIFEIKHYGKILNGSRSYYLCRTQPPFLTDMALQIFNQLDRSDVDANRAWLKRAIQAAIKEYHTIWVAEPRIDPKTGLSRYRPAGLGIPPETEATHFTHILEPFAHKHGLSILEFSEKYNDGVLKEPELDEYFLHDRAVRESGHDTTYRFEKRCANLATIDLQALLYKYEIDIGTAIREVFDDELELEEDFPLAPFPITPAAYAKTTRESSKGRSQSSDEWFKRAEFRKQMIGKYLWNDNKSLYFDYDTAKEQQILYESVTALWALWAGCASEEQAWKLVTQSLKKFEVLGGLVSGTEESRGKISLDRPNRQWDYPYVLPPHQTMAWVGLERYGYLEDAQRLAYRFLYMMTTAFVDFNGVVPEKFDAVKLSHLVDAEYGNQGIDFKMVPREGFGWMNAAYQVGLSFLNSHMRRAVAACTSPEVFFSAANNGTEQVLQDMTSDPLGLAMDSLEIVTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2Y4</accession>
    <name>A0ABQ8W2Y4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_748352</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="19120" checksum="2ACB4343A2268741" modified="2025-10-08" version="1">MPMCSMNMLWNTQIVDTCIVFRSWHISTNTAFLFSCLAIVALGVLYEYLRVLQKLIDTRIALSLVKDKRSRSRSSSGRSSPEIPLEEEGLLSGRVFQAKVTGVPVPLPSRIFRAVLYGISVFLSFFLMLVFMTYNAYLILSVVLGAALGHFIFGGSVDPDSILSTDGKGMACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZTQ0</accession>
    <name>A0A9W8ZTQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Rab-type small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8J55DRAFT_528335</name>
        <name evidence="14" type="ORF">C8R41DRAFT_494426</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Protein transport. Probably involved in vesicular traffic.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000050">
        <property type="protein sequence ID" value="KAJ4465496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZTQ0"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000363">
        <property type="entry name" value="Secretion related GTPase srgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4465496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4480318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="208" mass="23098" checksum="732805924776297C" modified="2023-11-08" version="1">MPPPHYDFLIKLLLIGDSGVGKSCLLLRFCDDAWTPSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDERSFNNIRTWHANIEQHASEGVNKILVGNKSDWTDKKAVTEEQGRELADELGIKFIETSAKVNEGVEEAFFTLARDIKTRLIDSQGDAAGSSNNTNDGSVQVTQRPSSATSGCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B421</accession>
    <name>A0A9W9B421_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8J55DRAFT_539374</name>
        <name evidence="15" type="ORF">C8R41DRAFT_902430</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000001">
        <property type="protein sequence ID" value="KAJ4496127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A9W9B421"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019158">
        <property type="term" value="F:mannokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000156">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.367.20:FF:000009">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="13">
        <location>
            <begin position="43"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="14">
        <location>
            <begin position="249"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4495319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4496127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="500" mass="55845" checksum="D205A2100125932D" modified="2023-11-08" version="1">MVASRRGSGSITLPTGQTMAIHTRTHEEEDLPHATKKTMADHLRKYESLFTLTPQRMRMIVEAFKDSLELGLQKPKQVVPMIPTFVFGWPTGQESGDFLALDLGGTNLRVCLVTLQGEGKFEMTQTKYRLTEEQKQDEGTKLFDFCAECLKTFIDTNFTDEDGNSLLKPGELLPLGFTFSYPCYQTRIDHGELIRWTKGFGVKNTEGRDVAEMFRQSIEKYELPVQMTALINDTTGTLIASHYVNPKTKIAVIFGTGCNAAYMEDVKNIEKINDLGINEKDQMAINCEWGAFDSFEHEHLPRTKYDIIVDETSNKPGEQAFEKLISGRYLGEILRLVICELIDEGVLFLGQETYKLETPYVFETAFLSLMESDPTDELLMIIGIFTHFFAVETTLAERQFFRALAMLIGRRAARLSACGIAAIVGKMGYLDEGCLVGADGSLYNKYPGFADRVHEGLIDVFGEKGNNIKTVHAEDGSGVGSAIIAAMTKVRRDAGLYPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DKV1</accession>
    <name>A0A9W9DKV1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_457556</name>
        <name evidence="9" type="ORF">C8R41DRAFT_554854</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000023">
        <property type="protein sequence ID" value="KAJ4474588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DKV1"/>
    <dbReference type="OrthoDB" id="1109245at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.740:FF:000001">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000051">
        <property type="entry name" value="40S ribosomal protein S4, X isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00485">
        <property type="entry name" value="Ribosomal_eS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_eS4_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_eS4_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_eS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018199">
        <property type="entry name" value="Ribosomal_eS4_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00528">
        <property type="entry name" value="RIBOSOMAL_S4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="8">
        <location>
            <begin position="42"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4474550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4474588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="262" mass="29625" checksum="4B49B4AFC1159844" modified="2023-11-08" version="1">MARGPKKHLKRLAAPSSWMLDKLSGTYAPRPSPGPHKLRECLPLTVFLRNRLKYALTGREVTSIVMQRLIKIDGKVRTDPTYPAGFMDVISIEKSGEHFRLLYDVKGRFAIHRITPEEATYKLLKVKKVAIGARGVPHVVTHDGRTIRYPDPLIKVNDTIKFDIEQGKITDFVKFDTGNLVMITGGRNMGRAGVIVHREKHIGDWDIVHVKDSLDRTFATRISNIFVIGEGSKPWISLPKGKGTKLTISEERDLRRKRAAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9E0V5</accession>
    <name>A0A9W9E0V5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_106273</name>
        <name evidence="10" type="ORF">C8R41DRAFT_356258</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="JANVFS010000002">
        <property type="protein sequence ID" value="KAJ4494845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9E0V5"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4494845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="305" mass="34960" checksum="195DDAF3DBD2C61A" modified="2023-11-08" version="1">MMESEIDGWIEQLSQCKQLSEADVKRLCEKTREILMDESNVQPVRCPVTVCGDIHGQFHDLSELFRIGGNSPDTNYLFMGDYVDRGYYSVETVTLLVAMKLRYRDRVTILRGNHESRQITQVYGFYDECLRKYGNANVWRYFTDLFDYLPLTALIDNQIFCLHGGLSPSIDTLDHVRSIDRVQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLVARAHQLVMEGYSWGQDRNVVTIFSAPNYCYRCGNQAAIMEIDEKLSYSFLQFDPAPRAGEPLVSRRVPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW08</accession>
    <name>A0ABQ8UW08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000161">
        <property type="protein sequence ID" value="KAJ4463519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="12591" checksum="CAFEF25F6617DFD2" modified="2025-10-08" version="1">MVAFGRGSELKARLLLRNITLLDATHMQKWLKEKVKAQSLNIRMQPTLKRCLEFKDNEENTGKQMKGMDIENNENEMEDDEEDARLRMRGMDIENDENNNEREGMCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX66</accession>
    <name>A0ABQ8UX66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_782768</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000140">
        <property type="protein sequence ID" value="KAJ4464491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4464491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="486" mass="54695" checksum="CA8307DEF6BD2AE6" modified="2025-10-08" version="1">MSGFSSPLFRVPRGHACVRCRQRKLKCSGTRPTCTECERANAEDECEYIGKTERSKACILQDEIDRLQARVRDLEKAGPILLHQPYKETSRPSNHTSDLSEDLSKQLIVTFMENANELCFFLNSARFRVWIENPVQQHRAPPPAALMSVVLLWGVHLSQDSTLRQLEESLFARVLRETAGISSAHRPDNFLYNLQTEFLLARYLFSTGKIIEGRYHVSCALSIGVGSGINKIRSSQPPSPRYAAISLLPPVSDMIEEGERIRCCWSGFMLDKSWAAALETSSDMLCPAEIPGAQTDTPWPQDEEVYEQGGNFLPEGYSFTTLNFIRGIPTSDLGDSIEATLVKAVFCWERACNLTKDTWTLCKPPRSICPLAQPLKAASEEYIEYLISYDQRRQCIARFISTLSYSEDIKGLIPSKALKRLKAHSMAHAANIEILRILPSFEQNEDSQPQTRSMVSSAEEIMKLLASPLLHTLQYIDSVMGVRFVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY17</accession>
    <name>A0ABQ8UY17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_97909</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="10">
        <location>
            <begin position="286"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="118"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4465473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="444" mass="49995" checksum="0E4E6A3D39F69BA6" modified="2025-10-08" version="1">MSSHGQFIQEIIRGFYDFFRLIIPEPQNRIPIALDVIPYSLSWFIPFFFLAYLARRPETYLIRLLLLPIVITTTLASAFRYCWTIPALNVYNWGQGLAAEVVIAKALEYALTPEGMLRMGESQPNQPKGKAKAKHYSNGDAQNIDADSRLSPPKHRRSHFISAFGDALNLAHEMRGSGWKFGVGTHIPKPVRPLERKEFINVTLWSFVKHFLLLDFIESIIKLFPGVGTPAGGSIFYQNLPILQRYIVSTTIHMLTGTALLSGFHMVYDLSTIIAVYVCDDSPSSWPPVMDHPWTADSMHVFWAKRWHQLLKRTFVVYGGIPGKWVAGNIGALIGTFIASGLFHECAIYAMGQGFDPVVPAFFALQGPILILERVWRIVTGKRVGGWIGRLWVYSMMFFFAQPMIDSWHRRGLGGGMVIPPFISPARVVLPLLVRAFDATVLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYL9</accession>
    <name>A0ABQ8UYL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_780909</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="108"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4466036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="161" mass="18678" checksum="14817A0696457309" modified="2025-10-08" version="1">MYTVSDRRNAIRPYVLSIQIDLKHNRPWRCEFCTKFARESVWMTSEWLQLKTPSMVSYVHLVCNSEIGECAQTLSAINSEMQSLAGAPPRPLPKLSRNGTKYPMAASCVNCNNEAKESRKHLKQCNRCKITRYCSTDCQRADWARHKVFCKTVKEVKWVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ26</accession>
    <name>A0ABQ8UZ26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HotDog domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_926764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000133">
        <property type="protein sequence ID" value="KAJ4464842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF57">
        <property type="entry name" value="DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisomal multifunctional enzyme type 2-like N-terminal" evidence="2">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="185"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="316" mass="33915" checksum="4B12BCB7E8137422" modified="2025-10-08" version="1">MAAEISKLIGYELPDRPVSWLKRDLILYALGIGAKDDSDDLSFIYELDPNFAAFPTYPVVLTFKGDSQELNLFAETMKSSALPGLPPVDLGKSVHGSQSIEILKPLPLASGPGWKWKTKYTGVSENKSGVVITNENLLVDPQGVPYARLYSSSFNIGMKITGQKFAKVIAGPPQAKPIPKDRKADWVVRQQSASDQALLYRLSGDYNPLHIDPQVGRAAGFGGTILHGLATFGFAARALLNAIAYNEPEALKFFGVRFTSPVKPGDVLETHAWEVGPGPDGTIEVAFVTKNLTSGKDALGGGIAYITKAQAILAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ32</accession>
    <name>A0ABQ8UZ32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7598 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_803339</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056019">
        <property type="entry name" value="DUF7598"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24535">
        <property type="entry name" value="DUF7598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7598" evidence="3">
        <location>
            <begin position="75"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4466581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="35622" checksum="C47C28FA77461E69" modified="2025-10-08" version="1">MLPLRAYTFIGLNAVRALSVIAMILVFSSSIEVMVTNIKAVNYYEAHKGENNATMSAMNMDYIAGSTVPNQPAGIFWAVVSSLLIIFQTVILILSECSWPISFFDHFFPVLGSAFGTGALGIFQCLIGAQILSHHVDEFTLVSAFFLFSLGCLNMFLGLIFRESIKSKRSITSWRSESKAVLPTIHDPRPVFVNVTPAYTGNSEKPQLASEFGSIRSTDKSGYGFGRQGEKAAGLRGFILQRPEESLPRYVSPTPPASPPTVHVALARNRSTTSSFASPQPARESVQSASHYDDDERSTDTEEEDEEVIRQHRPPVFKSSRTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZD0</accession>
    <name>A0ABQ8UZD0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_780519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="1">
        <location>
            <begin position="53"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="22217" checksum="04BAD98049BF54CF" modified="2025-10-08" version="1">MLLDIPLSFHRQVRQIISSVKTLTHILLSSATNRSAKYPSLHHILAVDSTTLKIDIRQKPRAGINASTFYAYAGIYAMAIPTYHIRLISKAFPWSIEIKSTTPITCEAVWDALHSALQENIADSEWGMLAGEKKLRETIEKAAKKRGQSDADKALKRIDWLGDGTIFRGLEKVEDFQKIRLLPGSDPVAETWVVKMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZY1</accession>
    <name>A0ABQ8UZY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HotDog domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_49519</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03442">
        <property type="entry name" value="BFIT_BACH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655:SF0">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="5">
        <location>
            <begin position="48"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="HotDog ACOT-type" evidence="5">
        <location>
            <begin position="288"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4467575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="468" mass="52704" checksum="A6CADA4AA3ED3CA0" modified="2025-10-08" version="1">MPMRIPSLWAEARLTIAREEERTYITKSSEVTISPSSDDLPPRNMRDSYTEFVLPIASNPNLLEEYVNASGGIRTGKLMEHLDSLAGSISYKHVLGPTKSELKVEEMGLYIVTAAVERIDMLRPLTPSHDLRLSGQVIYTGRSSMEVVVRIERIAAKETPEKDETILLGRFSMVCRNAKTNQAYPVGPLIISTEEEKALFSIGHELKRRRASRAQRSLSRVPPSSQEAAALHENYLKFGAAISQHSYGHQQTSSEIKSVHSDFTTLGDSNGSSVLNGSNHIAELVPMGETRIERCMLMFPQERNVHQKIFGGYLMRLAYELGFSNASMFCRGRVRFLGLDEISFKLPVPIGSILRLNSVILYDDFLRQREENGETNVYQLVHVGVKANVVDIKTGTEKTTNEFRFTWRGEEKLLASGTTESMESQKSVKVRRVVPKTYGEAMLWLEARRAVTVGDEIRELTVKRFENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0I7</accession>
    <name>A0ABQ8V0I7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_927076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF260">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047367360" evidence="1">
        <location>
            <begin position="18"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="503" mass="54563" checksum="1061C4398069F17E" modified="2025-10-08" version="1">MLWAVLILSLLQNSVLSSIVNSQEALSFQPIASLPVANASKSFWIDTPGANLLGNEGSIGPLTEDADVCIIGAGMTGISATYHLAKAIEKLGLEGSSLEVKAVVLEAREFCSGATGRNGGHLTPYSFFNYREYEEKYGTIEALKSLQIENRTAMAMVSIIQEHQLADVVDLVAGGHLMLISSEEEYASLKEEYLAASRAGLNVGDVEWLPEEDVDRIYGASYSAVKFPAFNFWPLKFVTQLYLLANSSTPHFSLSLHTHTPVTSVTPLSSSRIWSVNTPRGSVKCSHVLHATNGYASHLLPQFGGPSGIIPTRGQIVVMRAATPVNDSWKASWGGLDHYWFPRPVNGSISDHGTEDGKENPVVILGGGRHIGGPAFEQYETDDSVVNTALGEELRAFLPETFPHMFNKGEDAEMEWTGIMGYTSMADPFVGPIVEHLQSGATSGIFTGQYIAAGYSGHGMPRAFSCAEAIANMIIAAIQNKSWSTPEWLPKRYLTKNRSQEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0K9</accession>
    <name>A0ABQ8V0K9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_73689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="122" mass="13952" checksum="76EF9257ABA7E649" modified="2025-10-08" version="1">MRKPPIHTDTSMPKLYQNPVSTNMTLSTAVQLQTFVILCYTPRMNPYDISVPCDGSIEEILCYPVTVRRHSPRGSSQIQLLRSCCSCCWHCVLWNTLYPSFQPRLRSDILRAWGESVLVFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0X3</accession>
    <name>A0ABQ8V0X3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PCI domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_37146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="263"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="476" mass="53975" checksum="5C22C36FA47FC1A1" modified="2025-10-08" version="1">MDDDDADYMQGSDDEDYGFDYSDGEDAEESGSADVENMYYKAKSKKEDNPEGALKEFRAIVDQEKEKGDWGFKALKQATKLLYLVLRRPNDALQTYIQLLTYTKSAVTRNYSEKTINGILDYVGGGKGGSVEVDVLEKFYQATKTALEEAKNDRLSAKTNLKLAKLWLDRKEYTRLSKLIRDLHVATGPAGDGDDQSQRGTQLLEIYALEIQMYNETRNFKKLKEIYNATNNVRSAIPHPRIMGVIKECGGKMWMGERQWDKASEDFFESFRNYDEAGSPQRIQVLKYLVLANMLMGSEVNPFDSQETKPYKNDPEIKAMTDLVDAYQRREVHSAEKILRDSGATILGDSFIRAYIGELLRSLRTQYLIDLIKPYSRLELSFLAKQLNVEIQEVEDLLIGLILEGKVEGRIDQVGMRLELDRKQSLEKKRYSALQKWTENIEAVHGAVVGKTGSSGRGGDPGMSMSDVYMRDAGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V100</accession>
    <name>A0ABQ8V100_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_855655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="247" mass="28140" checksum="2146DF39B9836A8B" modified="2025-10-08" version="1">MPLHHHLAMSENIPPACNIPPAYKALYAPTLPTFRVRLARQLPHETNLIKTAILHGMLKPEDAPTRLDSLMNALMDESQVPKDANDEYLQYLLGRSKKKIDKEKQKIDKGKGLLRRWVEEDQGIRDSDIWDDLLQVVNLTLKGDDFGDILFGEITPELRAKAPWLPSKSSQILPTALALPKQWKDIEKDEEPGKRWVAQYILGPLNEALEPVWNDMGLAPPHPRPPAVPIITQRQRLALVLQNRFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1F1</accession>
    <name>A0ABQ8V1F1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_782066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="133" mass="14866" checksum="2619736C22A21B6A" modified="2025-10-08" version="1" fragment="single">DMPRDSRISKPAWMGLRASADMRSSIQLALTQGASQVAQTILEGITRIPHLAVAVCDLSSRMFLYRSQLTPNILEDILPKVNTAIPHFVQSITHAFSENDMQNNSRGDHWFSIAGHDRNNRQVKLLLSLSKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V287</accession>
    <name>A0ABQ8V287_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin N-terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_890928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF40">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G09800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="52"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="289" mass="32359" checksum="0AFFA0E0699386DB" modified="2025-10-08" version="1">MNGVNGKYHQSLDGLAENPLRRTWRGNEQGTIELSSVPKFDDPYQEREWIKEHMAAAFRYWGKCGYGEGVSGHITVRDPVLPDHYWMNPFAEHFSTMTKSMLVLVDPDGYVSPHGAQLPINSSGFYIHSAIHKARPDVKAAAHCHSIHGKTWSAFGRPIDILTQDSCLFHDNLGVYQNFGGVVLAEQEGQNIANALGPKWKACILQNHGLLTLGNTVDEAVFLFGALDRLCQVQLLAESAEANGIRKSVISQEDAEFTAKTIQWWENVYVNFQPEYKLLLQETNGAFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2M3</accession>
    <name>A0ABQ8V2M3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_711749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="108" mass="12494" checksum="6BC5D897FB923D84" modified="2025-10-08" version="1" fragment="single">PFETLRKAQLKEGLEPWSPFQNKGEWELARWLMESGASQGKIDQFLKLTKVQSSNKDMKPPFKNTHTFLQFIDSLPRGPGFTCTPIKITGNIKDMNGDFRTEILELWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2N2</accession>
    <name>A0ABQ8V2N2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-conjugating enzyme/RWD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_897813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="148" mass="16558" checksum="362026BFF5763665" modified="2025-10-08" version="1">MSLAGLPKETERLVADPAPGITASPHDDNLRYFDVTIQGPEGSPFQSGVFKLELFLPEEYPMAPPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSVQALLSAPNPDDPLATDVAKHYKENEQDAQRVSQEWTEKYASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R4</accession>
    <name>A0ABQ8V2R4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_601549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="871"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
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        <location>
            <begin position="671"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="774"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="809"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="901" mass="95591" checksum="D29426A5AD7AD1C9" modified="2025-10-08" version="1">MTARASYVDYPRPIIGSPGSGALVSGKRFSHRYTQSAPSALLPLPSLSSSLTSISSAIANSSTLTTPTCDTYDEYTASSSSVTLNILSSITGSGSTTPEVDQEFDVPTPKASPRASSRIPVPVLLVNRTRRYTAPTESKATTLDRVPSYSDLSFTQRSQNLRKSSPSFIPIFSNSVRSALGSKKKLASKSTLRPPSATVLSHRRRTFSPATPRPNPSQPSQPKPTLAISFISSPDSCPSPSLPAMVSSKTDVDRLYSSHRRYTSTASSEIGKAMDSAARKCYGAASCSTSLCSPQTGSYRTSSSSSSLVPGSQAETMSSKRMTPGARHTHGMHNIHKTASNSSQTLLDNPSNSSRAAARMLRSTLARDETNLSLSVSLSEKRRRHSSAAPTLAVGNDGLESSPPTTLKPHEKILRARLERVLLANVQADGASLYGVDDGSRVRASSTESADIGRKRSRSRAGSDTGMLGWFWSKGSTIDDEYEDGGDEAISLPVPPIACPHVQAFSQTSHFARFTSPQQPALPSSPQNPSRMRSHTSPVSSNSQGAFQTSSQSPRPRHAFSLETVPSVGEMSVEDNGADADIQADTTKADTTRAIGNSVTQSQNQVQKTPRMPTPPPTPPPRRPETSGIRSTGQPPSVSGSSASHTPQNRTRRSTEPMHTSHQMPQQSAFALATAIRSSSRSSTPATASAFPAEAKSRRKSTPVSSYVQATTLNLSERQRSIPASTGAGPEPRCHPRNVNNPAGHLDFVQCENQHLGVKKADARTQHVRQATMPANLSSSLPSPSSASYLQTRHRLSNSTSNPLPPSPTVHISHPSPSSSASMSSPSPTSPSQPPSPSTTASSFNAHTASMRCRQIDGYVSFAAVAGLEEPHGDDEYADGPEGLAGRSSSDRGWVGRLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3L2</accession>
    <name>A0ABQ8V3L2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA splicing factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_897668</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022209">
        <property type="entry name" value="CWC25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051376">
        <property type="entry name" value="CWC25_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12542">
        <property type="entry name" value="CWC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="9">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="161"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="384"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4472668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="50204" checksum="D801BC329CC28486" modified="2025-10-08" version="1">MGGGDLNMKKSWHPLLLKNQERVWLEEKKALEEKKKLDQLRKEKEEERQLQELQRLQEEKTGKKRAEKLEWMYTTPATGSTQNSNDLEDYLLGKKRVDKILTADENAKLGASHKNFIAVQNANNVRDIASKIREDPLLAIKQQEQASYEALMANPLRLREMQMRNGIVPKKDKKERKREKEEKRRLKEEKKQRKLQDRYSRSPSPLNDRYDSRDRHDRRYNQRRSPSPYRRSSSPYSRSNRRNDRDHEPSIRRRQSRSPISRQGRDDDRHPRSRSSSTTPLSDNARGRDNYSYDRPGESSSRGRAISPRRGKRSRSPSLTRESRYESYNHKRPRRSPSPRTAPSTRADDDRAARLAAMALSAEATKIERQERLKKLLEKEKADMAAEEATRSKSKGMGGFLSHESKKVFGGSGGLEDRIRRGRGGMVIDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V473</accession>
    <name>A0ABQ8V473_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="273" mass="29367" checksum="71083573C8010420" modified="2025-10-08" version="1">MVTPYGWFQFTHHAEAETAERALEGEPALTILFGATSVRKLIDFGIMAKSKPQREAPAKADYISEHTSALEESIFHLNGMLMNVKRTQKWCIRIYSPLAHILIHLSYIFHTRNNRGFSIVWSTQNTESALTSAARGACFTDADLPLDNIELDYLSFLTLKVFPTDPNTSFVCSVSVPAPGAALVFLTNDLSEMEGAPLTMFATTTAMNAGNTATVDASVLATSNGNNGKSPLGSSSKGSVDGGVVFRESVAGLLLRAGSIGALGLFLRIVFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4U3</accession>
    <name>A0ABQ8V4U3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_613818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="386"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="695"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="777"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="932"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="748"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="788"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="851"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="941"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4470760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="988" mass="105863" checksum="6A0B1360DE5C342E" modified="2025-10-08" version="1">MTFAVLRALHALIGDALDDVERIYAEAGNSSHNSRTSTPGTPSTASTARSPTHKSSNSAQGHAYASPPPSPLISSYFQSQPSSQDRSTTPLSTLDFPSLDLPFDPNSPSENLTSHPVVISAVNRIVAAAGQMSATVQIPFLTLCDAGMGFHLPSCLRLLEASHTVEILREAGPDGLHVKLIAEKNGVDKNKLAHILRLLATHHILREVSPNVFANNRLSSILDTRKPVEKLMRNPETKYSDTNGVSAFFGMCTDELFKSAGFLTETYFLSPQKHKNGREPTRAPFNHAFGCEGVGFFGWLEGEGIDGRQVNGPGRGVDLIPGVVIPGNGSINHKRGTSSIGKAADMYSGKGSPTNKPRDPLANPNRFRLERFGKAMTGTASWEVPGAVLNGFDWQSLPKGSVIVDVGGGIGSTSMLLAHAYSDGRDISSDEDVPGLKFIIQDREVVVDMGEKAWKDKCPELVDSGVARFQVHDFFLPQPVKNAAVFLLRVVLHDWPDAFAQRILLRLREAAMPDTKLLIADFVLPLACADNFGSAQDEDETGLTEIQGAETMLAPAPLLPNLGKASANGYWMDMTMQCMFNGQERTLREIVSLAHSAGWKVTKVTKAPGSLFGHIVAIPIEIPIQRRARAGSGSAFFDIPNSNYMGGSAVDPHDEALLDVRQMGRASSRCGTPTFGSRMDLPSYEEARAKFGGGIRGALRRPSTSVLTRPPMKPSILPAAGSAKKKRPSPLAVVPQSPSPVPRNISSPRPPPPPVPHSPLKRRISHAQLNQIYSSQQPSLLPAPQPSQSPRIPGSSLPLSRRASLANLSNQASISREPPPPLPTNFALRSSDRASPAPSQMPLSPASPVFSRLNSSGLSLRSPTPASPNLSHRRSYVTLSPSAIPKKRVDNSIGGLPSTLGRRGNTLMRTLELSELTNRGVNGRGRIGPLKFGDELSLDPASDDGNDSESIEESLPGGSVLAAAARIESLRSTPSQPSMSALNRQYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5D7</accession>
    <name>A0ABQ8V5D7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GMC oxidoreductase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_850327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF78">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="275"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4471904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="669" mass="72903" checksum="2DC1E1D328F0C5E6" modified="2025-10-08" version="1">MNSAPNEFDIIFGGGGTAACVAAGRLASANPTLRILVLEAGEHTKYEDSHVQPGRYFGHLSPASTTLDFHVGKPSKSLAGRSLVVPSGRCIGGGSSVNFTMYTRASASDYDDWEGQYKNPGWGSKDLLPLLRKTETYQIRPHQPTHGYSGPLKVSWGGHVTNIGDQFLKVAAAIDNDRMYTEDVNDFYECNKYGKWPKWIDGETGKRSDPAHYYIYNQEANKNLVIRTGQRVKRVIFEGEKAVGLEYVADIALRPDVDETPQQAYASRLVVLSGGAFGSPAILERSGIGAADLLAKYDVPVKVDLPGVGESFQDHNICFVPYQASDEADTFDALIRGDIAETTKNFDLWTEGGKGLLAANGMDAGIKIRPVAEEDFKDLGPDFEERWNEYFANAPDKPVIWFGPSSFLLGDHTTAPVRKYYSLAYVNEYPVSMGSVHISSGQDPHAPSDFNPAFLNHPADFATLRWGYKKTREIARRMKFYRGEHLPIHPKFSANSEALCNGNSAGPAALDAPNLKYTEDDDRAIDDFHKQFIQTSWHSLGTCAMKPREDGGVVDPRLNVYGTRNLKVAGNLSIAPANVGANTYSSALTVGEKAAVIIAEDLGFPLDGVGILETSEQSLSGFAEPVSAPSTKTQIPDDFAGLQGIEGLTINSMVKDEYPNSKSSMITVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5N9</accession>
    <name>A0ABQ8V5N9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_846786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="282" mass="32523" checksum="3AD80DB97AEC552C" modified="2025-10-08" version="1">MSRKHRKTQKQKKAAKNRASNANEKETFADGEYRARSQQAREFSDEMYRRLELQRLNCQAWEAYVQEEVDIYTGSGAYNIILKESLGVLATLGVLLVLLFTDEVFIKLFEFQSHSNAIFSVVYLFCCGNTGIALSMHAYNGQIWASIAADGLPFLRSARPIYYGLHPQGILPSSQRNPFSKRVDKYGPWNTVIAPLRILFLKFLSKFSFIILYFPFLVFWLLSRSYDAFPTQWWTIVGALGTFTGILKLCHSFLGEPIKEDDRMAEEHMLYHMFWRGLGFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Y8</accession>
    <name>A0ABQ8V5Y8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_549250</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4475114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="465" mass="51589" checksum="D81EB30650F81FF1" modified="2025-10-08" version="1">MYNTDTVKRLKSGHPPESDIIHLSALGNSIIILNSSKTVGDLLEKRSSLYSSRPPTVMLGELMGWGSTLIFRPNDDSWKAQRRIINQAIPPTDPKRFHPKQLSATHDLLRVLPYSDNVMKSLQVWAAAFIMDVTYGLDPEEAKPYLPTAMAALESMSIAGTPGAFYVDQIPILKYVPEWVPGADFQRKAREWSDLRVEMTETAFNVTKKRMAMGTATPSLTLAALEQMDRTQNLASQEEVIKKASVTAYGGGSDTIVAALGSFILNMLMNPEIQTKAHEQLEKVLGPGDLPSFSDEPLLPYITAIAQEALRHNPVTPLAFPHALTQDDIYEGYFLPKGSIIMPNVWSILHDKEEYPEPDLFNPSRFLRVDGKINPKVKDPATAAFGFGRRACPGKHIALASLWIAVASILTCYSIEPELDEHGKPVKPKAEWYPGPTLFNHPLPFKCRFVPRSKDVQTSLGVTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Z4</accession>
    <name>A0ABQ8V5Z4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="833" mass="94598" checksum="39A201BAB89E73C1" modified="2025-10-08" version="1">MSAQRLAHATSKLEVLTVTNSPQAQYHRRTTVYTLHSTSALTKLEAIVEAPSTPSTQRLEAIVEAPSTSSTQRCSLSPTAPKAQSNHRSAVHSIYSTVSPREIKNGGAHCHQQPQALIRLKLIIEEPYALSTKWLKIIVKAILTLSIQWLVHAKSKIEVLVVTDSPRDPRKASKKQKTEETITGSPVKRLSDLRRETNVNTTAHIRAPNTIKKYEEVIKRGRKWLEDFLDAEEKARDCDENEEDEDGSDFKEDRSTAALQQTASEFRGCLDGKPRESTPEAIAMFMSWKCYTEGRKIATANQIHAAFKYYYTHLNGDKYRGPWRYDGAQREWVGNPCDAAQVADLHDGCKRKDGEAERHHSMPASIIVMERLYAYSITICPDDYPVADVKSLALKTSHLRFRAYASLGFTIWTRNSETSNLQAKHIDRNPLPRPGATPSDPPFIQINLRDRKNWQKKQGKNETQLNGHRYNLYPQKIRAICAYTHLSIWMSFSEQYILRRKYAPEDYIFPNINVNGITIQNKPVTPEAVQKMINEFTTAAGVPGAFTTHCFRRGGAQYRFMFAPVGERWTLARIRWWGGWAPNEKRDTLIRYLLDELNTYEEDHSDALAPVDRRASESHAGEAAEMGPVSAAECRNLFQMQSFFIQKTVKNEVFAALTTPSLVQQIGSVPGYRHTNGPNISPSFIYPAIHSTNSVSIPSEIYAPPPPLIPPSKNPQTTYIQASSMSSSPPAFLPGLEHLPTIPNIRPGPEGWKQIVHDWEHADPNRHHHYALRDWKTEWAKATKLASNYNKRKLIATEFIEEFERDEEKFKLAYPSCKKGIEQLLHEIHIEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V622</accession>
    <name>A0ABQ8V622_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1,4-benzoquinone reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_773962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="202" mass="21682" checksum="F6FB6D8CA9D1D9CD" modified="2025-10-08" version="1">MAPRVAIIIYSMFGHIAKMAEAVKSGVENAGGSVKIFQIPETLPQEILDKMHAPGKPNYPVINVDQLTEFDAFLFGIPTRYGNFPAQWKTFWDATGGLWGKGALAGKYASVFFSTASPGGGQESTAMNAMSTLVHHGMIFIPLGYSVAFPQLTNMDEVRGGSPWGAGCFAGPSGTRQPSALELEIATIQGKHFYTTVSKVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Y7</accession>
    <name>A0ABQ8V6Y7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_845021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="281" mass="30892" checksum="7E7BCC463A8C1DF7" modified="2025-10-08" version="1">MAYNYAKSLGWNSVAAAAVFAALYTPLALYFVAKIIQERRKVLFTMTLFCTIRVAAFIMRAISAGVTSAGDNEGLFIATEVFFSVGFFGLLYATYSLVMDRLDLCDNDDKASVPTPIIGNLLRLTRNRRFFRMALIVPMALGIAGINLASSDPSSSIGTSLREASAIIFLVLTVFQVLQTLVLIKAEHEGKDHLEYTSTSFGTKHASLLFGIISLLLLIREIFTVVTINNIAKANNEHLWYPLIALPEILCVLVYTIPGVIPPKGYSIDLPASQDRDRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Y8</accession>
    <name>A0ABQ8V6Y8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_897693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35585">
        <property type="entry name" value="HHE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35585:SF1">
        <property type="entry name" value="HHE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="194" mass="22083" checksum="49EA60C48CB4FE2D" modified="2025-10-08" version="1">MSSQRTLTDAIKEDHEEMYEYYDNYKKAAGDADAQARWARQLTWEIARHAVGEEIVVYPLMEQHMGHEGIKLADQDRADHQKVKEQLYQLESLAAGTTDYDTLMTQIMAHLRQHNDSEETQDLPQLELKLGQEGSQHAAATFTKTKKFAPTRPHPSAPNKPPAETLVGFLALPIDKLKDMFSKFPTEEMKKAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Z3</accession>
    <name>A0ABQ8V7Z3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="157" mass="18247" checksum="89EF6673E877165E" modified="2025-10-08" version="1">MSVNRDYEEVISEIQHYQEEWCNGEKLGAVDALKFENLILSSKRNDNKHSTSDHTVLHNKRVFLEEPLGKLVLMTLSPIERKATWRVELTKIDTIESGNNSMRRRQISAAENEALDTTELHEVNHWIRTNWAKDAMHQRRQATSSPHLTSKRSASRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V815</accession>
    <name>A0ABQ8V815_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_771855</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044996940" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="11">
        <location>
            <begin position="334"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="297"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4479446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="38215" checksum="4C1BE0A1476198A2" modified="2025-10-08" version="1">MYRLSILPVLSLLLSPLVDAATQQLVQVTADIGPNPNNVGMYVYKPAKLASPLPLIVAIHECTASGPIYFESTQYATLADEYGYLVVYPSSPRSGTCFDVNTPQTLTHNGGGDSQGIASMVTYSIATYGVDPSLVYVTGTSSGAMMTNVMAGSYPELFQAASVYSGVAFGCFAGASSWNTQCAEGELIQTPQQWGQEVANAYPGYTGSRPKMMLWHGTADETLLYPNYGEEIKQWTDVFGLSQTPTTTTQNDPQSGYTMTTYGTEVVGYSAAGVGHTVPVHETIDLAWFGITGSTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAGTVAEWGQCGGIGYTGPTTCASGTTCTVSNAYYSQCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8P3</accession>
    <name>A0ABQ8V8P3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-aspartate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_843055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="12"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4479878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="42523" checksum="3D853938F6CDF248" modified="2025-10-08" version="1">MSSLNEAQKKEIIVLGAGVIGLTTAIKILEDKGAEYNVTIIAETFPTDPRTIKYTSFWAGAQYVATRTEDLNLRRMERESFDVVWAMSEPGSGVAEGCLLRCTDYAHLPEEERHPDGEDHPCAFMPDFRQLRADELASGAVQGFACTAVTFDIPRYLPYLLARFTSGGGSIIRGSVTHIQQVLEGGTKLFASANSVRKPSPPDAVILCVGLGARFLGGIEDKDVIPVRGQTVLLRAPWVRTMPVLKDLKDGAMPPYVIPRKGGDVIVGGTYHPNDWYPHPRPEITERILARGLKLCPDLAPPEVRAEREPTVDDLRPLILDVGVGFRPYRNGGVRVGVEWMDSSPLKDKGKKVPVVFNYGHGGNGYQAAWGSAIIALEYLEGALKNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8S8</accession>
    <name>A0ABQ8V8S8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Oxidized purine nucleoside triphosphate hydrolase</fullName>
            <ecNumber evidence="13">3.6.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">2-hydroxy-dATP diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">7,8-dihydro-8-oxoguanine triphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">8-oxo-dGTPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Methylated purine nucleoside triphosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Nucleoside diphosphate-linked moiety X motif 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">C8R41DRAFT_886409</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Oxidized purine nucleoside triphosphate hydrolase which is a prominent sanitizer of the oxidized nucleotide pool. Catalyzes the hydrolysis of 2-oxo-dATP (2-hydroxy-dATP) into 2-oxo-dAMP. Also has a significant hydrolase activity toward 2-oxo-ATP, 8-oxo-dGTP and 8-oxo-dATP. Through the hydrolysis of oxidized purine nucleoside triphosphates, prevents their incorporation into DNA and the subsequent transversions A:T to C:G and G:C to T:A. Also catalyzes the hydrolysis of methylated purine nucleoside triphosphate preventing their integration into DNA. Through this antimutagenic activity protects cells from oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2-oxo-ATP + H2O = 2-oxo-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67392"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71395"/>
            <dbReference type="ChEBI" id="CHEBI:172878"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:67393"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2-oxo-dATP + H2O = 2-oxo-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31583"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:63212"/>
            <dbReference type="ChEBI" id="CHEBI:77897"/>
            <dbReference type="EC" id="3.6.1.56"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:31584"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>8-oxo-dATP + H2O = 8-oxo-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:65396"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71361"/>
            <dbReference type="ChEBI" id="CHEBI:172871"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:65397"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>8-oxo-dGTP + H2O = 8-oxo-dGMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31575"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:63224"/>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:31576"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>N(6)-methyl-ATP + H2O = N(6)-methyl-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
            <dbReference type="ChEBI" id="CHEBI:172873"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:67609"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>N(6)-methyl-dATP + H2O = N(6)-methyl-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:169976"/>
            <dbReference type="ChEBI" id="CHEBI:172872"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:67605"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>O(6)-methyl-dGTP + H2O = O(6)-methyl-dGMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67600"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:169974"/>
            <dbReference type="ChEBI" id="CHEBI:169975"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:67601"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.56" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03427">
        <property type="entry name" value="NUDIX_MTH1_Nudt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003563">
        <property type="entry name" value="8ODP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758">
        <property type="entry name" value="7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758:SF2">
        <property type="entry name" value="OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01403">
        <property type="entry name" value="8OXTPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="24">
        <location>
            <begin position="37"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00032071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00053094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAJ4479874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="210" mass="23691" checksum="A6755A184EEB1263" modified="2025-10-08" version="1">MSISSMPESIPGLEKDFNLLRETVSGGTSTKWIDHKKVKFYTNAFIFHENKVLLGYKKRGFGLHKYNGFGGKVELGETSPEAAARELEEEAGIKSALKHIGVLFFLSDDEDCAFHIDIYRGDGFTGVITESEEMRPEWFFTHADDSLDTGAAPSIPYEQLWETDPYWFPYLLSNTPFRGRADFRTDPDEGKLLPCKWWFGVLGGSAEVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V952</accession>
    <name>A0ABQ8V952_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SMAD/FHA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_776235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="188"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="290" mass="33686" checksum="93FD4D3D87FCE0BC" modified="2025-10-08" version="1">MPRDSDREYFSRSRRAHNGVDSRSRNSRSDSGRKYDDGPSQRGDRGSNYRRTEEARYGYGEEERERERRRDRERYDRDGDHNRDRDRDYYESQRSSRRRSESPHLRSSRPHSRSRSKSPVNKAKPNFGASGLLAAETNTVQSIDGKNSTVLKYNEPPEARKPVLGWRLYVFKGEEQVELLHIQRQSAYLIGRDRLVADIPIEHPSCSKQHAIIPDLANFERTDRLVQEKDEFGGAKGVVKPFIIDLESTNGTHVNDNKIPASRYYELKLNDVIKFGTSNREYVLLHDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9F8</accession>
    <name>A0ABQ8V9F8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_179853</name>
        <name evidence="7" type="ORF">C8R41DRAFT_776081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000182">
        <property type="protein sequence ID" value="KAJ4463290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF2">
        <property type="entry name" value="AMIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="5">
        <location>
            <begin position="75"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4463290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4472687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="561" mass="61456" checksum="FFFD925FC30B96A4" modified="2025-10-08" version="1">MSDWKAIAAKKKAKQQALIPKEWILKLDDIPIGADVSRVPETCGLMTVIEIQITNSDVDDLLEKLAAGEWSSVLVTTAFYKRAIIAHQLTNCLTEIFVERALFRAAELDDHLRKTGAVIGPLHGLPVSLKDQINIKGLESCMGYVSWVGTYAERNSVLTDILENAGAVLFVKTNVPQTLMWSETFNHVFGRTSNPYNRSLTSGGSSGGEGALVAMRGSPLGVGSDIGGSIRIPAAFCGTYGLRPSYGRVPYAGCVNSLEGQDSVASVLGPLSNSLSGIKSFMKAVIDARPWLKDPLAVRKRWSDDEYNLVDHGNGKNLCFAIMWDDGLVVPHPPIIRGLEVVKKALLNAGHEVIDWKPLKHAEMFKCLHDIWAAGAAEDFKVVTAVTGEPVIASMDLDDEISAVGKHEEHNNATVVIPGLSAYDLWQTHRQKRILREEHLQLWEDTIQITGTGRAVDAIISPAAPYTAIRHGKNNTAQYTMVWNLLDYSSLVIPVSRVDPEIDRVKAPHNFYNQKDKANYDLYNPADFANAPISVQLVGRTCEEEAVIAMGEIVVAALKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9X3</accession>
    <name>A0ABQ8V9X3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gti1/Pac2 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="466" mass="50928" checksum="F7E21584BE82684C" modified="2025-10-08" version="1">MSTSSASHQPPPTTWNEPPWTGWIETTGDALLILEAARRGWIPRVTRRLVDSERKMITSGSVFVFDEEESGIKRWTDGFFWSPSRILGNFLLYRETDKRGPGHKGARPQEEAAEVSDASPSSETHSLSRPKSETSNNHLGFDKLRERSLMGSLTNSYKFKSDGLMKKTFSKTFSLSIGGVAQHLISYYRIEDVENGRLRSPSSLPELASLDISPEYLDKTHFRNPPKVEVGPDGVPRYRGEADDIEAVSTSSIISAPLSTGLPLLTDGRVTDMPKRPNKRFEPYPTAAQPAAKRQRKRPNHNTNNDTSPESPTSKDRDRQRGRSSSQTPTPSSSSSQPPVPYPDPDPSIASVGGVSGVGVASAQPAYTGYYPMPGYGPPPAMYHYPSPQQLPSMPAQGLNVPSAGSPGPGPPGHPTYYGYRQPFPAYPGSYPPQATMTWASYPAQPALPSQLQPIVTSVKEGEHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAD1</accession>
    <name>A0ABQ8VAD1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxisomal biogenesis factor 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_769792</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4483987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="265" mass="29390" checksum="12C36D6255DCC917" modified="2025-10-08" version="1">MAAIASQVVLHPTVSQGLKFGGTTLGRDKANHFQYFTRTPNLCSTFRSIQYFARFYAWFLLRKGDKEAAARWNALKIHLATARKLLRLGKPFEHLQAGLKAALISGPAGEQITTIGKQIAYFAYLSFDALVWVNAVKFYSFSTETSNKISKLSNRFWLAGILLSIVNGALKSVRLAKEERRSKRSKALGGEKDVSQEAEQEMRLSTTIASRDATRYQLVIDLLDLWIPATALGISSMNDGVLGIFGLITSVMAGHKQWQSVNGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAS6</accession>
    <name>A0ABQ8VAS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_921744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="46507" checksum="5C615DF65A3C4048" modified="2025-10-08" version="1">MPYDITSIRQDALRSEISRLRGKPVTEMEQLVFDVVLEGGQRMIARCERAGPDQEDPREVQRRLHKHATVLDTLQKAYDIPVPLVYHIEPDPKVIGAPWILMDRISGGMLHYVVSRWDKAVKEDNMKVVLAQHATVYACIFDTIMPEPLSSMLAEERQYDHIDPMPTAFDIKLHYESFTDDPDLLRARAYRQETATFIAHRFWKLMHDGEHSAEADGHPELPVLHKLKALVPAFIPTVEAYLELDDNGQSLLGSKKLHHYDPSVSNIMVDFDTAKITGIIDWEFTVAVPALLSAAYPEWIRYDGQQSPTSHWSSHLLQLSPDKFEYGKWREMYEDNVGKISANYLKAMRAGRELQELVDWCRFAVYGLPLDERMAFLDSWVNSKAAEFGVDVESVPIRRKRDWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB59</accession>
    <name>A0ABQ8VB59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_844616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="18"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="490" mass="54988" checksum="566866DA39EF55BC" modified="2025-10-08" version="1">MNRYKMYSGFTPALPPPKHPMSSLPPELLAEIFQYCSTYNADAPLLLGSVNRRFREIVHSHPAVWYKLRLRLGFGTEFARIQKAGLWFKNRGACPLKVFLNITNTCAPRSDTSEQEWFSHNYPFLIALFRKNIHRIHALTLQSDTELKAYHLLDAITASSPVSPTESLQLHSLHFQITADIPPMPSGWSPVFESFSLFPQLDSLKLINHILPALTPPNIVHLQNLSIVRPLTAPPLPTLKILRMISSAPSLIHLDIDSRISGEPLSDFHVETELPALKSLSLRINNLPSTLKLLASASLEKLRLTDLDGRRPRAGEELGSVMANLTRELKTKDGSSGGLDLLKSLEIAGVHCVSSTSAHWDWCIRHLPRLESLTLNKSGFVSLIKVLTEIQPEHPDIQGGFYCPRLSYVHLSSVDALLLLQDLKMKRPSLTVEWDNGGPVWHHSIPDHPRTTFSYTTGGYGFASLFDYDRRHIEDTQVKGVSLTDEDSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB70</accession>
    <name>A0ABQ8VB70_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_921560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="2">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="73" mass="7964" checksum="6AFC03E3E4C3B0A4" modified="2025-10-08" version="1">MSDSEYIHALNNLAQSRHLTVSYSNTHTGTQHGGVWISIVYINGVEHGRATCTTRKDAQKAAARIALSVLELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBC5</accession>
    <name>A0ABQ8VBC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_839783</name>
        <name evidence="1" type="ORF">C8R41DRAFT_840745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4483151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="77" mass="8567" checksum="0F8A8878F1DACDC7" modified="2025-10-08" version="1">MANLCYSQLCSQLCPFLFLIIGGTASFSISPILSSQKSQTHHHSAGLHMFQHWGLEVEEDNGLVQKCSQDLPLYCIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBE5</accession>
    <name>A0ABQ8VBE5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_838738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="694"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="837"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="910"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="933"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="969"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4485097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1171" mass="128863" checksum="21C19BD2DFF8E74D" modified="2025-10-08" version="1">MQRYNNNKRPVRKRPIRDRTVTTLTGNDDEHNQEVLFSGPSASGAAADKTNNNKPSGFNDDHPSVFSDSNPVNSGLASFENLQYSAMPSPSTFGFGYNSFVGPMNPGGVTAQQNHLSSSSSTYYNQPMLPPGKSDLEILENLKERIKKGQHEFFRATPMPELLAGLYLGPSSGSAQDLDAVQEKGSVAVAAAASTNGDGNVGNNKTSSSTTTMTSPSAIIPSENSPSKITSMSTFHQEINGQKSSNENGSKSATSMPPNPTDSSSHGLNNSINMGLPAKPPLTNAHGTSMNGSFTKDERSPSSFGREIYPPPPSRTRASSSSGASSSLPHSHSVSAPENTHATNKYYDARDIRDTRERDRDNHNNNRDKDHDSPRPSSVSVSGAEYASVRYGPIRDIRDIRDNKDGITSMRRDGRRPSTAFHYDSASYREEDYLPPSDDYRRLSGPPSTPQALPNDRYSRPPPSTDERHRLDDRYPERVPLPLSSTPSSSIPTSSPYGPSFRPDERERHRYDTHSNTNYPANHNHHVPHAGITPPTRPNHVHNSTHVLASRYNENRPQIGESPVAAAAAAEREQRERAAAEREQREKLERERDRERMGTTRDLRERDMRPPPPPPSQVHQAAPAKLEERITSRAPTLQERLSQPPVGESSRTLSLEERLSSHPNTGTGTNPAAGTPASPASSKGGSVAPVPPDSASSAASTTTIGTAERAVPASASSGGGPNSVATGGLTNSRSFPPTAARDETGAVRGRYSSPTPSERDRERERSRTYPSPPPYDRDRDHRRVSSGGGGNILGREYVYDERDRSRDRRREWPPSADEQYFRSSSVTPVGASRPAPSTYPSPPPPGTSDRYERDNRNGLRALWEQRDHERRISAPGVSAAATTSSPRSEVPSRGGSGIPIPIPIPIPVSADERDRDRDRSYRSSDSRYPPPSSSVTGTPSPYTHGRVRPRSPSPNTRGPPIKRSRDDLYPSSSSAAAYPSPSTYGGSSPPNSNRTSRRMSDYPPPPVSMSMEEYARPLPIQSMPLSQLSREIRNPRDAYYDKYDKYDSRPPPSSGGASAYPPQSSIPANYDRPRSPPPPRSAAYPAGYRDPRDVRDSRDSRDVSDMRDPRDIVRDARDPRDIRDLRDVRDVRDMRDIRDPRDMRDMRDVRDMRYPRDDPRRFSMPPPPLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCM0</accession>
    <name>A0ABQ8VCM0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_981859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467:SF1">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="106"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4487421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="279" mass="30634" checksum="0D4A75771A011634" modified="2025-10-08" version="1">MPEALNITEAQSAQSVLSEASERIEKPSSTVDDSTVPNEPPAFRVYKPSSGSSFIPSTDLPDSYFNPTASDLKLAQTQLSARTQALTNAPLQLRTTREAAEKAKKDRWPNTTIRVRFTDRTQLEKVFPSTDKIKSVYAFVRNSLREDAKPIKFILYQPPRRDLKVSDLKVKNLTLAELELAPSSVLLLRFEDESLNGSDVPAPLASDILALAESLPAPLSLEDTSSASRSSTKKVDKTLNGSAAGEKKIPKWLKLGSKSFPLSFSPLVLTSTCRKIIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD86</accession>
    <name>A0ABQ8VD86_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nife hydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_836842</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="7">
        <location>
            <begin position="199"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="16"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4487469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="469" mass="52713" checksum="02721247B45EB4A3" modified="2025-10-08" version="1">MASMLLRSVARSTVAKLPTSSNTLRRSLTSSPVTRLAEPVSAADSAHTQGAKNVFEYHTVEDLQGMHASEILAETGTRADAKMRHFTVNFGPQHPAAHGVLRLILELNGEEILRADPHIGLLHRGTEKLIEYKTYIQALPYFDRLDYVSMMTNELCYSRAVEKLLNIEVPDRAKWIRTLFGEITRILNHLMAVLTHAMDVGALTPFLWGFEEREKLMEFYERVSGARLHSAYVRPGGVAFDLPHGLLDDIFQWATQFGSRIDEIEEVVTGNRIWKERTVGVGVVTKEEALNFSFSGVMLRGSGVPWDLRRTQPYDMYDQVEFDIPIGVNGDCYDRYLCRVQEMRESLRIISQCLNKITPGAIKVDDHKLVPPPRASMKESMESLIHHFKIFSEGYSVPPGETYSAIEAPKGEMGVYLVSDGTNRPYRCSIRAPGFAHLAGADFVMRHHMLADAVAIIGTMDLVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE11</accession>
    <name>A0ABQ8VE11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cation efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_769981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 63C, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="10"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="346"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="137"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4484048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="482" mass="52582" checksum="C8F4B1BF0283B4E1" modified="2025-10-08" version="1">MTITRATRIKILLAIDVLFFFVELIVGYAVGSLALVADSFHMLNDVMSLIVALYAIKLTAENAADSRYSYGWHRAEILAALVNGVFLLALCFSIFLEAVERFFNTPEVSNPRLVVVVGSLGLASNIVGLFLFHEHGHSHEHPHNQPSTPSISSSSGKDTPSRPTSPLRAGRSLAPRSRSESFSSLYGHPAATRASLVQTAQEIADARSPSPSHRIRLPGESLEYSPLRAGKVTLTEGPDSEVATAFNAATPSETTALLSSSESPRPRSQHSHAGSMNMRALVLHVLGDALGNIGVIATGLVIWLSSWGFKYYFDPVISLVITVIIFSSALPLVRSASFILLQGVPSTVSLDEVRSSVLAVEGVLSLHELHVWQLSESKIVASVHVMTSRKHDFMPVAAKIREALHHHGIHSSTIQPEYARIHIPEEQLMTSEDTSCLILCPEDQECDPQENACCREHFLPFQFAPWVNKHVHSYSAPPITDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE87</accession>
    <name>A0ABQ8VE87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_411289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4487494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="382" mass="40739" checksum="16ACB82D6A6F7814" modified="2025-10-08" version="1">MVHHSLIRQHRRSDIFASPTVSGITGALTAGAGATTATVLAEAQNTASNGTPSLQGLATGVAGVSTISSTSSSSSFRSTASVSSSSSSASSSSSISMSTVIGACVGTLVGVLALVLLAIWLYKRSDPTKKRRPNTRAGPGLQPNWNKLGDDDDKWEGMDKKTETAEIAPMEKLTMFKKSTPSIRTAYTSKTEELPAFDFGSHPFSQYHPNLAKELASADEPPVPPFRHRADSAAVSWDGDTIGGASFLSAPSKRMSGAMSPTVEIARPTPALTNSEPHRWESAEVVNLEGHIAEVIDPLDSENPFEHPMERRKSQHNPFFGSSSSEVPIAKDYKGKGRAREITPLPPIPVSNPFVDDSENLDKTPTRPTFNHQVIGSVSYHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEB2</accession>
    <name>A0ABQ8VEB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4485084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="172" mass="18585" checksum="EE05DBEA1834E1CA" modified="2025-10-08" version="1">MRVGVKVVWGVISGILGEVHGNAWGDLLYPANFKLDKGHPKEKAGPFGLKSAPNGLQQTPFGPHALINRSSLKPQSLPPPPLLPSPTSIPETHAALPNVVPPPPTFGDLLSCIMDSPSHGASTPHKRPPPEHDIALRGSKRPRIDSLNTFMRSHQPNIPEIFDVSMTRSLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEE3</accession>
    <name>A0ABQ8VEE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_910746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formin GTPase-binding" evidence="2">
        <location>
            <begin position="69"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="637" mass="69706" checksum="963AC1D1AD92A3DF" modified="2025-10-08" version="1">MFKSILPSKRITSSDFTMVTTLADGAPNGKENQPSSNFFTQSTRNTKGGPAGSDKGFTDKKKRGAAKEMNQLEHGDDMHEAFDQLLDELQIPSTLRPKLVGMDSSVKAAMLKSSRGMSLNIKSTFPVIPEMPLTSQPMTLRRTRSIDTLESPRPAKPTLDYDLRPPMAPFTFSDPSSRSASSTGSPRKSSHSRGISLGAGIMSRSQVNLLGNSSTLDLTATAKSGKEKGPGSSRIISPTKSVSILAGASSTELDVEQVKKLRLLLRNESASWTEEFLRSGGYAALLTRMNEILEVEWREEQHDDQILHELLRCFKALSTSSIGCVALRSSSPTPWGQLVTLLYSDKKPGEVATRQLIVELLHILFDLYPSSSLPSSGRSPHREIWDSDSAPLGSGNVITLPAPHKSLFSFIRSLLLTPAPPTAEAPASPLSPHEFIENLHRPRIYKTYLQELSDVCRDYFWVFCHPNNTIWLLSETDEGRVEKPRAPGGMTGGVEFEAMNYFTSHLKFINAVAKATDDLNLPKDNELSAHRFHSDMFASGFERLILISRKASTTYYPTLHLELARYVAFAGRAQFELPWTVSRLIGLPPPGLCKNSVSPSLTSGRSTPATPSRRTARGPASALPLQPGSPSRGALAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEV8</accession>
    <name>A0ABQ8VEV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_836036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="21578" checksum="1DDA5FC862709F91" modified="2025-10-08" version="1">MSYDSSLLAAAPQATREMRQEGYNPYILDQEQKKSNASSAPVVGGSANDLTSKEYPPNSNLHNPSALPKTPFYRTRKGIIIIAILAIVVIAAVIGGAVGGTSHKSHTLSTVSSSSSAPTDSQAVQGASTSTAGSATATITTTLTTVIQSATQPGGAIGPVTTTITSTITESAAPTNTGSANTNGVGNGNQDVNSSGFVGSKRRLSRVIKRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF42</accession>
    <name>A0ABQ8VF42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_833478</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="207"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="571"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="10">
        <location>
            <begin position="938"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="410"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1137"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1137"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1167"/>
            <end position="1180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4491877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1194" mass="133736" checksum="5CF1015A3D3723ED" modified="2025-10-08" version="1">MSTFTAVGPDDELLSDVVPSNIVSRQPSTGADGESEADFYDDELASEPDEPVPSKGKGKSKAKGRKSTGGGRKGASKAAEHQLADQRVEMDKAKEADAVKRYSYLLGQTELFKHFVDIKRARDSEYAALLDAQQGKGNGKKKGKNGKAGNGGARHRKSEKEEDEELLKDGEKELGGAEDMPMVFEESPSYIEGTMRPYQLQGLNWMISLHHNGLNGILADEMGLGKTLQTISFLGYLYHHLSTPGPHLIIVPKSTLQNWAREFAQWTPFFRVVILTGSKDERQSIIQDQLLAFSQGEEQDGGLALPFDVLITSYEICLIERSTLKKFSFQYIVIDEAHRIKNSSSLLSQIVRAFASRGRLLITGTPLQNSLEELWALLNFIAPEIFVSFSDLDSFLNKDDAPTAATITTADTAVNNASEKDPAAMEVDGTEVEQKPNEGENQSVAQGKQKEQTDQEKKSQKVVEALHKILRPFLLRRVKADVEKGLLPKKEINIYVPLTPMQRRWYRSVLEKDIDAVNGLTGKKEGKTRLMNLVMQLRKVTCHPYLFDGAEPGPPYTTDEHLIENSGKMVILDRLLVKMKAKGSRVLIFSQMSRVLDILEDYCLFRGFKYNRIDGGTAHEDRIVAIDEYNAPGSEKFIFLLTTRAGGLGINLTTADIVVLYDSDWNPQADLQAMDRAHRIGQTKQVYVYRFITEGSVEERMLERAAQKLRLDQLVIQQGRGGPSGAAQTNKAANKDELLEMITHGAEKIIHGGDNGDSDDLDIDAIIAKGEERTSELNSKYEGLNLEDLSNFKSDASVQQWEGEDFRSGRKALNFNLLSLSKRERKSNYSVDNYFKDTLRAGPSKIEKGPKLPKAPKQVTIQDFQFFPPELSVLQERELAVHKRLNGIPATVREPTAEDTADTLAELEIERQQEQEFIDTAEPLVDSEIALKESYLEHGFPNWSRRDFQQFVKGLEAYGWDQPAEVYAADIQEKTAEEVEKYYRTFKRKWKTLSEYPRIEVRIAEGIAKRNKRSNLEFLLDQKINSVRYPMQELELNYPTTKGKVYSEEEDRYLLCRLYHYGLNSSGSSASTNGAGAGSGGAGLGGIGDAEIYEKIKRDISEFPVFRFDWFFKSRSAAELGRRCNTLLAMIEREAEAEEKVRQEEEQKKSGSKSKKRGADEIVKNEIASSRPATPSGSVTSASAAKRPAKKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFF3</accession>
    <name>A0ABQ8VFF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF2">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="744" mass="84824" checksum="9573862CC459FD5F" modified="2025-10-08" version="1">MPGKPKQNHVNHTLRILLKQLLAFWEGVYYTRTARHRIGRKVFVVLLPIVCDTEAAIQISGFAAHNHTYFCRRCLLPISDIYNLDPETWIMRDPAKHRELAFEWKVASRARREAIYKAHGIRFTELMELSYWDPILYTVIDDMHFGYLGLFKTHLCEIWGIDHERNSGDGLHPDLSDKKRMKLSNASLRNFLNEIRENEQSLGAILLAEKKGVLWYLCFWLKLRTGLSSKQQMVEQILQWCSTVENEQVPEIPPVDYNQVPDGWEGNNSVETHEAVVEVSESEASNLESFNSQASSRASLVTSSIALSVTNADALPPVSRPAPTFVFSKDSTFEKLKSKLLNLAAKPPSLNTKKIILRALCQDLNILYNPSDSNKTLAGRLMVYHQENGAKDDEDVSQMRYNQFKRAFEEDEPSKSIMMSQLLRHLEKLCTEYHIPPFNSNISSGSLKKEKLAQWLILWRREHHDSALRQTSPRNVIGKDLLAEIWADMARSVLPSWIQTAPSRWGIPSAGKLSADEYKVLFPDVMLASNHHLALHIVTDLENMGPGHARSTPVFERINHLLQEIKKNGHLGEVEVTMMNSYGRIANLQLLLNNYLELREEIGEALTMLTDIDREDHRGIFAGTDLSAWSSTEFNETPTHIERSTLDRIVQQLCRMYSVQASHWDGKVARASHILGGAALGRVIYSTGYRQNSIIFRDEGKIIAGTIDKIIKHSHPHPFTQEVIATTYVEAIAMEPINREDDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFJ7</accession>
    <name>A0ABQ8VFJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_344185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118:SF12">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="24259" checksum="F662F87586D8C754" modified="2025-10-08" version="1">MSVFTMSLVDLSHPFDPERMSIPPGLPQFISCPIATVPKDGFSMHTVSFGSHTGTHIDAPSHFIADGKTIDQIPLTALVGSAVVLDFTYKGPKEVITWADITKSPHADKIEPGIIVLFHTGWSKHWAADEQIYWDHPYLSPDVAEQLIARGISVIGIDCASPDKSLLEPPWNFPFHLAFLGRGGFIVENLTTLGELGPKVMVNLLPINLVGCDGAPVRGIAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGT6</accession>
    <name>A0ABQ8VGT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Integral membrane protein S linking to the trans Golgi network-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_835958</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952:SF0">
        <property type="entry name" value="PROTEIN SYS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4489111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="218" mass="24744" checksum="BF33354A3367CFCF" modified="2025-10-08" version="1">MTSQISNWDPILLISQIVSMQTLHYITLSIFIPPLLTVFAEPTSLAYEGGASNIGMIMDWREMAGRPTVRGIYDSEKWGSYSWAWSGGKILGFTWREDQLRGGMDPIRGWIIAFCWMLACSADIYYLYILVRRPRLILDFAITLAFNHLVLTTYYSSSVPTSIFFWAVVLAGTAMTIVIAEQLCVKREMNEGLNVAPARAQEEDLDEMELGQLLPRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGU5</accession>
    <name>A0ABQ8VGU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_437750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="207" mass="23082" checksum="7614611BDFE17865" modified="2025-10-08" version="1">MSFSMTHSVVLPYPIDHVFHTLSDADRMERLQKLTPEAQKFSLLPPDIVSLPHSALSSLTHSDTMPEGCPRPRELPPLSLDQTADSEMRTFQRTYFEFSGTVPIPFGLFNRALSVAGAQIVDEEAKVVLFESGVVAQGIKEVKLRTFRAILLPGDSNGSEEPTKSGTEVKETVWGTSPFGLSLLLKFLAPWVHRHHMELYSKLFEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI66</accession>
    <name>A0ABQ8VI66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="555" mass="62440" checksum="CE6DD3393759FB13" modified="2025-10-08" version="1">MEFLRISYKGSNLPEKLKLLLGSLQIQLEGNFSSNPSFPTPSPSPERPSKAARATKYLSIKTRPNPPWLASKSRTTCEAGIQVDLDLAAQDNHDPPLSLHRALQDRCNMHHQLHICHPDFPNCNQDQARDLHQTRDQNRDVGQSRVVDQSRALNQNRAVDQSRARYRNRTFNHDHNRARDLDCNHNRAFDDDQNHAFDDDQNRAFDQNRAFNHDRALDLDRDQNRARNFDSPSFCRRTISAEDADEDGEELWIADQVPDFDMSHNSLQDHGTFPKKDMIHSQQNSDLDKLLLSLLDEPAPTQNSFAALPASALTTSSTQHPRSYFATSNSDPGSRKRRHSQANHEEHIPRQRHGAVNAHADPVEPRPDCNRNGGSASRKRLRVDSQANRQDIEEEEEEEAPNGTQYLYEASQTPHPPPKEVTDVALAWMLRLTGGVGWGSDKWAEDIRGLVAAVDWEEASEALSSDSLLHLAQRCRRAEKVNTGSTFIQMMYELFLAAKVNSILHENAKDGKLIASAYPALSSVTGTGISRHSSRWGRLASAAWASFTIPIQGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIK3</accession>
    <name>A0ABQ8VIK3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_918899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat PWP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="365"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="407"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="494"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="6">
        <location>
            <begin position="777"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="221"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="921" mass="101210" checksum="6376031963721AE7" modified="2025-10-08" version="1">MKPNYKFSNICGTVYCQGNVLFTADGNSLLSPVGNRVSSFDLLNNKSFTFPFENRKNIAKIALSPDGNVLISVDGDGRALLVNYKRGVVLHHFDFKKPVKDISFSPDGKFIAVTHGSHIQVWQTPNHLVREFAPFVLHRTYTGHMDDVLSIQWAEDSQCFITTSRDMTARLFTLHPVKDYRPKTFAGHRDAVLGAYFSKDGNTIYTVSRDGAVFTWKGKVEAPNSDSSDDNEDDDDQPIASTSNGLSSSSSSPLSHKIIHTRWGVHRREYFNVPGSNVSTSSRPAKVITTTYHASSSLLIVGFSTGIFGLWELPAFTNLHTLSISQESISSLNVSPSGEWLAFGAAHLGQLLVWEWQSESYILKQQGHFLDLNTLTYSPDGQTVATGGDDGKLKLWSMQSSFCFVTFNEHSAPITGVAFARYGTNVVFSASLDGTVRAYDLVRYRNFRTFTSPSPAQFNCIAVDPSGEVVAAGSTDTYEVFLWSVQTGKLLDILTGHEAPVSTLEFCPEGTNQLASGSWDRSVRVWSVFGRSRASEAFTLNADVLALTWRPDGKELAVSTLDGQITFFDVAQSKQTNVINGRNDISGGRLTNSRTSAANSTAGKSFNSLAYTADGRCVLAGGNSKYVVLYDVREGEGVLLRKFTISENLSLDGTEEFLDSRRVNEAGVNIDSLMIEDEEEDADRRRVDSTLPGAQGGDMSVRKYKRAARTKCVRFSPTGRSWAAASTEGLLIYSLDSLNTADFDPFDLSLDLTPSSVLSTLHSKSYLPALVMAFRLNEAPLLQTVFEGIPRGDIKLVVRQLPVMYLGPLLRFVGGVFLKKTPHVEFGLLWVHAVLMIHGRVLRAGGGAVGGHSSSNMGGDMPSVLRVVKTALGECEETLSRLCDQNMSNLSYVVDQSRLSRLREQQERQRQDVPKKDVESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIY9</accession>
    <name>A0ABQ8VIY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SPX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_834462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="509"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="590"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="670"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="740"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="779"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="828"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="107"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4489779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="851" mass="94848" checksum="00B72CED2A2167F2" modified="2025-10-08" version="1">MKFSSALKFNAVSEWWEEYIDYDYLKKYIYQLEKQQQSLTSSYRDLESNERTSLVGRPSDAATDSIFIPLLDKELKKVALFYEHQEKELFDELAELEALVQNQEELGLDGDHYADDDEYDEEDEESLSRSPERHRRRRLSSSANVNRNTSGPGESSYVRQSPVRQRHSISSSEGEMEDSLASLRRSISPNRTMQKLANTFSLMKDSVTSSGLSETIWTARTNYAYDTRLLFKRRITNLYVLFSSLRSYVEVNYSGFRKVLKKYDKVTYSELKDHYLHDVVEQTVPFLPDSKDRLNGAIDRLIHLYTKCVARGNQNLAKQQLKLFQRENIAWERDTVWRQMIGRERRGEGVASNLLGATLVKEPQPGLFAIPTPFGRLSITRRFLYLVIALVVFAVLLNVEVVQGHEANRCFAVLVFCTVLWATEAIPLFVTSILVPLLLVCFQVVRGPKPDYEHLSAPDATKFIFSAMFSPTIMLLIGGFTISSALSKTSIDRILITRVLSLAGTRPSVVLLAFMCVSCFASMWISNVAAPTLCFTLIKPILRTLPPKTSFAPALILGIALAANIGGQSSPISSPQNLIALQNMDEPLDWGSWFAVALPVSAISILLIWGLLLASYRPARSPDGESEIEIRPIRATKEPFTRQQYWVSFVCLATIVLWCIAHSIEDYVGDMGVIAIIPIIAFFSTGILKKDDFEQFTWTIVFLAMGGIALGKGVTSSGLLDIMGELVRDLVDGFSLYNVVLILSPIVLVISTFISHTIASVLLVPIAKEVATSLGGDHQNLLIFVTALICSAGMGMPVSGFPNQTAATQEDDLGELYLSNIDFLKNGIPASIFATLVVATVGYLLMIAIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJN4</accession>
    <name>A0ABQ8VJN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_866215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25896" checksum="A76DE930BC61E8F5" modified="2025-10-08" version="1">MVTQKSQLNIVMGAMTFGKEGTNGARVHDVKDVEAILDEFSKRGHTEIDTARVYCAGTSEEILGQIDWKAKGLKLETKLVARHTEFAQFSLSPPLQHIHIPYPIVPRNPISKPDPNATPNQTPVEEIYHTYEDLNKHLLRSLKALNTETPYEVTMKAVNDLYKEGYFKKFAISNYMAWEVAEIVGICKANGYILPSAYQGIYNAVHRAAEPELFPCLRKFGISSYIRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJN8</accession>
    <name>A0ABQ8VJN8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF4048 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="296"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="69775" checksum="239C642B7729497D" modified="2025-10-08" version="1">MTTSGPRPLRLASSAESPTITSPTPLTPRSAGLDSSKRNSSFRLNSRRQSSISYNPRSRDDPLSPALFSPRHAASVLTPDSPGPSSRPNLSRSASVGSRVPRRTESRGERSPYSGADPSTPATVNWNRNRNSTGSLLAEERERPALTLVEKHAELLHFIAQKESKCLELRTQLSTHEAELLQLKRKWERIVFRGFEKSQANGERRLPSSTSPSPDSIPITNATHPPSAYIYSAASLSYLDSLSTQAQGAGSAAMLEALGGMKGIRESVQQGVGRFLGAVAGTNDPSYTTAHRRSLTHTPSQSSSSASTYATSSTRFSQSSQSSFGDIVPTSISEEDGDLMSDSNIDVTSIKRVKKHRPTHIGIVSDTGATPLVSPTRDFALESPPRTATPSTRAIHGGGNIRSRRKSRTFSSESPTEATGISISEELNRCADSDTNTSESLSSSLVDWGMGVSSPPPVDSPVPASRDGKINLNKRMSLPARTLNSGSGADSWMGSMVGKRWEDTISKNQKRASVLLSDVSQSISQSFPQSIIQALVSPPLSASSELAPPSGYHNGIKKQASPASASSTSLLDEDIPPEESGGSLTPLLEPSPAPFPVLSPTKLAPSSSEPQPKSPMKKKSSSSPAGVTNAGKTNKTGSKFISAVASQEDDDDDWNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJP1</accession>
    <name>A0ABQ8VJP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="279" mass="30803" checksum="59F237E1CC23BDDF" modified="2025-10-08" version="1">MTAPHASTSAAVSDAFGVPPSSPNRHDSDVDEIVSNVEEPSLGQLSLFKSVFGVGVSLARYIVDDPLWSTLAAAGLPCPTCVRGKKEGSCSLVPHLARCSNCDDKKPCVLGRLARFRYFSRKCSRDLAFARRFLEVHGDPGQRTRYSLPTEQWRVIYDRVEQSTNSTSALLKLNPLDDQDQGELDRQELREFRQRQPLVPGPSTPVPCTSPLVDGSSLLPPAPVTKKRKRPIKVDPGSTSKRRRPEQAVGPREVQITVAWSSSSVLLTFPIRRISICRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJY0</accession>
    <name>A0ABQ8VJY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_309408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="102" mass="10862" checksum="B73B837BC80861E3" modified="2025-10-08" version="1">MSTGKIAAQCSHATLACYKTLLSSNPAFLRQWESSGQIKIALKCFSEEELLTLQAQAQSLNLCARSIQDAGRTQVAAGSRTVLGIAGPAKLVNRITGTLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKS3</accession>
    <name>A0ABQ8VKS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Subtilisin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_824412</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF19">
        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046615437" evidence="9">
        <location>
            <begin position="20"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="10">
        <location>
            <begin position="213"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="610"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="633" mass="68770" checksum="DA53CEEC9E0317EB" modified="2025-10-08" version="1">MLALLSLPFICSWFGQVSSSLTPFVLHERRSRSPSGWVLERKHDASAVLPLRFGLTQSNIQNLEEYLYDISDPDSSNFGKHWTPLEVAKTFAPSAESVKVVHEWLIDNGIPKDRLRITPSQGWIEVDATVEEAEHLILADYYVYKHESGQEHIACNEYHLPQHVAPHVEIVTPSVHFDAIIRPTPMNRDTALMKTDITVVNTTYLGVGHCDTQISIDCLRALYDFDYTPIASGRNSYGIVEYTPQSFRQSDMDLFFTNYSISELIGRPPYQVSIDGGYQQTFNQSFDYVGESHLDLQYGMGLVTSKLNVTLYQVGDTVNPNTSFNNFLDALDGSYCNYEGGDDPTVDAIYPDTQAGGYDGPSACGTTKPAAVISTSYGYNEADLTPFYATRQCNEYAKLGLMGVTILYSSGDSGVAGNGQVCLNDDGSQSVNGTRFNPSFPGSCPYVTSVGATQIAAGNSVDDPEVAAARVTASGVFYSGGGFSNVFGIPNYQKDAVATYIKNFKTDNFTTSAYNSSGNSRGFPDVAVNGAAYVVAAEGEFILEWGTSASSPTMGSIIAMINDARLAIGKSTIGFINPTIYSTLFQEAFNDIRSGNNPGCGTEGFTAASGWDPLTGLGTPNFERLKELWLALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKX5</accession>
    <name>A0ABQ8VKX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_824588</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF54">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046143194" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="68"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="57468" checksum="6728EED431C9C089" modified="2025-10-08" version="1">MLLSLFLTTGLYSNIALARQEAFGTPATNLEAKACCTGLNSLLPGQVFWPSSDSYRAQQSSYYSGEQATMTPACRVSPNNTSDVSRILKFASAHECHFAVRTGGHMAWSGASNIGSEGFTIDMQQVKGVPTLSADKSVVSFGAGSRWRDVYTVLQLQNLTTVGGRVGDVGVGGFLLGGGIGFLSAEHGFGSDNIQNYEVVLVNGSIINANRKQHSNLYWGLKLGSTNFGVVTRFDMFTFSQGPVWGGSQFFAIKDASNLLERLVTFTEKLAEDPKGFFGLSLAWNPEAKDYIIWTLQTYLKPEAYPALWSGFESFTPLVDMMGIKNLTDITEEFQEADPGKHGRSRWLTMTYKANAQFHLDLYARGVELFEPYHGHAGVHWAVSVQPVPARLASASIENGGNPTCLKESEGNLWVMLITTDWLDPSDDHIMNTSAEALLKWAEDEAKRRGLFSPFIYMNYASGSEPVMVRSTDDQTLKKMIQVKKMYDPQGDLDKLWHGGFKLPRTEEHEPVTNYDRSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKZ9</accession>
    <name>A0ABQ8VKZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GLTSCR protein conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_823174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015671">
        <property type="entry name" value="GSCR1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15249">
        <property type="entry name" value="GLTSCR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GLTSCR protein conserved" evidence="2">
        <location>
            <begin position="101"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="421" mass="44810" checksum="96310ADB9A65B606" modified="2025-10-08" version="1">MSTISTFFPSSSSVPISNNSTQAKSLPYPAASRSQTPVSSSLAGPSIWRPPAHWDLDTNGRPANPPSNSIKKSPRTKDRTPEERDATVETSARFSSRIVSDHEAVLNPDVESPFVDTIDVVNRLLPYHIFFQPKEDLAPLLRDRKGKTKAADIEDLADTKFALDCHRRRKKLEDRFRKARVKGGAGSGFNPQLVVLTQSVLDSDRAEVAALNAELRAARGEYDRLERQKRATSNPPPPTPASRTSFYTAPTQSAVANGQSAYYRPYPYTYTSTFGTSPPAQAAAATPTFSAASNAPSLSPQVNTSIVPPPVTYPTTSAIPVQLPIAFMPALNRLGIIPVPTGSVSAGQPQPPAVLRGSSSNGTVLNLEINVAMLQPSQMSGLAVILNSLMSRSNSSSIPSAPAPSSGSSTGVLPPPADKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLF3</accession>
    <name>A0ABQ8VLF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_865777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.40">
        <property type="entry name" value="Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043094">
        <property type="entry name" value="Nab2/ZC3H14_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="79"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="283"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="551"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4497227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="594" mass="63397" checksum="FEDFF74159D5969F" modified="2025-10-08" version="1">MPFGLIIGTDRALALQQAIQDELMTRGYSPEADPVMAEYITIMIINNKTAAQITSELEDFFGSDFDPSFTDWLFKEAARGSTETETTLPEPSVELSERLAEPAPSRTTSHPANDISRRGSNPPRNGIYQQALSQALPSSSSSQKRPASARSPSPNHPNKIRRTEPPTGPRAMHRDSQLSNNPRSLLDRVGGPAVGGQQDEIQARIDTIVNTGDPNMIMAGGFPGMNSMDMNAMAAGMANPMMIQELMMNQMALMAHFSGIMNPGQFGGFPMQGVMPQEMGMPQQNMGVNGFQGQSSGSNRGRGTGGRGGRGASRGRGGPPISSVTSKIEEVPTESPAISTPIAAPTPSTIIKAPMSDATPSTAPSRPAYAVPERPQSPTLCKFGLKCTNAHCRWSHPSPVATAESGVVLSNDPCENGKYCKDKDCIKAHVSPATLKPQDHATPVPPPQTHSFAPSNPIPCRFGAACARPNCSFAHPQRQSNVQCKFGAACTRANCQFQHPPGRVLPTTFHQGLSENGPMVTVKNPEPGSMGRPSPHRTATFNHSGAGTGTRDHLEKQMREIEAKKGQAEQAVREAQVAAANVKKEDVKSVQITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLW5</accession>
    <name>A0ABQ8VLW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046343623" evidence="1">
        <location>
            <begin position="20"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="142" mass="15649" checksum="7CE1CD04361654CB" modified="2025-10-08" version="1">MRLVTSLIFILGFVSLASAAPLDSRRPSSHIDVTIAFEENPLEGIHTHLTQTYTEAVKEDVRSLVKSIAGRDLGAPKGSALLFHWIGTPSPDTAKPVMFDISTKDHGRYRVAMSHRTPMHDVIVTDSLGHPVRTHGDPYRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMA6</accession>
    <name>A0ABQ8VMA6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VIT-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_919266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="274"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="877"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4494297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1031" mass="112729" checksum="680ADF186E6941A0" modified="2025-10-08" version="1">MRPLPAPICRLYTPSYNFILTGCSVEVHIVDVHASVELSQRFSNPTGYTLNATYAFGLMVGAAVCGFEMVRKDGTRVEGRVRSKEEADKEFRQAKREGKTAALGREATHDVFSISVGNIQPFETVTINLRFIQALTEDENHDEVKFIFPRTYAQRYGVAPTVPSAARESETAIQPFDMKVAVQQAGLIKSISCPSGHPISFKRKSAKATSAEVTLKDASGFLTQDVILVVSAANLDNPRCFIEAHPLSPKHNTTAMALTFVPRFEVPDVSQGMEYIFMIDRSGSMYGRNIQLVKDALVVLLRSLPTKDTTFNLVSFGSRATTLWRHSREYTQSTVEEATNHVDSLEADYGGTEIPTALRTVFTSLQKPLRKPVAVFLLTDGSSWDVSACVSVVTDALRELPGPLPQSDDPNAQSFIRVFTLGIGPGASSNMCDSIARAGEGVAVYAQEGEEMVGKCARLVSAARTPPISIEVEWMGVKDSDETSEYQKEPDKIASVGHEDDTSAEKDKDTENDDDAKTLRNEPSSSSSPVNLFNPFITNLSRETGPSTKAKLNPKLPPPATIQQAPLVVPTIFPGTRTCIYAIIKSGSASFLNLMHNNDLLPTYVRVRGTVRATGRRVELKVPITRLLQPQPSQFSPSSSSSTSSKLYSGLSSLFTSPPPLTKPKPFLHILAAKALITDRQEGKHAFPSSIAESNSFKLDAEVRRSYIKMDIIRLGTTYGLTSEHTSFIAVDDREHMVSVSQNYHAQERSSKQNSARTSYHYLTGGFTESYDPTTEDMSSHPDEYPYIQEEYGSSYATRGGSSHYNPNTGIMHPPSPQLGSDHKPVTSSSLPPTPTSKNKLQGWFGKRQSVDGIRRPNMKGGASFFKRMSLSISMPSNTSNISNSETTSKTATPTSSPLVLRTAVASSGLNSSTTTTPSRTVDTSLMSSGERLASIARLQRFDGGFAWSTTIFSVLQLSFNDLDNMKRQLSEQNITADIAATVLAWVWLERNGGYEATEMAKKAGEWVGIQLGTQENEELKNKVLAVIPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMD9</accession>
    <name>A0ABQ8VMD9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="450" mass="51170" checksum="7C016F58D229451B" modified="2025-10-08" version="1">MGELYHHLQNSTAEILRKQDQVLQKQDHKIDKVVSHLAQNTEILGRIGETLDMLSAKSKHKGSPGHQDEGDSQRHGSGSNQGPQPSNDRDSAAKPSDGGAAGSATNRNNGNGDGEDGDDEGDSNDNPFFRYARKKQPARSGGVKHRPAEELKIKETMRKWLNEVMEGQDQLKEAVSQDEADKFTLLFKTNPLARPCSVDDFRYWIAGGPKSAWNKGASYVFVEILEKRKLIATPDVQTRDGIREAFLLRLKTLHASWMERQKMQEDNKNPRSLFSKRWQRKNTLFHRRREVIITFHSLESFLSFFDELGVAGMSSDDEDPGMKKPQVQYIIKEPKWQSVELKNLLRLFDYCHLEGRCTTEATRFGYTRGAPPRIRIDKNDRSSKTKYVSGLPANFYDAQWLEEQEPGWAKGGSGFVNEFVRPRKPIKLIFPADLLKTLKDRGYPRAQGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMT5</accession>
    <name>A0ABQ8VMT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_821632</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="5">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF22">
        <property type="entry name" value="CRYPTOCHROME DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="7">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="595"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="620" mass="70643" checksum="16BCECA8A5631C06" modified="2025-10-08" version="1">MYLIYLFRRDLRISDNPIFHHLQKHPQFCHILPLYILPPNQIEVSGFLQDPSLESPYPQARSRLGKLRRCGPHRAKFLAESIWDLKESLKHRGSDLIVRVGRMEDVVGQILKQKEFQGKVGAVWMTKDWASEEVDEELRIERAVKEEGDGKIEWKVWDGEEMLLNDNDFPTSDPAQVPDVFTSFRKSFEPLRDNIRVSYCSNRSQLPPVPPNVPTQAAPFSISTSLEDFISSLQKPVQDCGLGPPILKPQGASTAHPFIGGETSAHERILHLLVSGNLSTYKDTRNGLLGEDFSTKLSAYLALGCVTARQINAYMVAFEDGKDLPDFGIRLNTEVNLSNAKGFGNGENKGTAAVRFELLWRDYMRLCMRKFGDGLFSIEGFRERSQSRGPEDVQYRKNKPNSDTSYHWSNLSSPETRYAFDRFIRGETGTGLIDASMRELALTGYTSNRTRQNCASFLAKWLGIDWRLGAEWYECMLIDHDVANNWGNWAYVAGVGNNPRGRDASGGAEGRKFNPVKQAWDYDHNGEYVKAWIAEFEGVPSGNDLGDGKQGWRDVLFQGWKVDDIFRHTKDKRERELREKLKRLEWVNRPLGKIRYQPKDQVQGKKGSDAKRGGTQRTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMX1</accession>
    <name>A0ABQ8VMX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cora-like Mg2+ transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_758647</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="387"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="573" mass="65265" checksum="4351C38316BB903D" modified="2025-10-08" version="1">MTESRYTRPPPPHRHAGPSAPWPWIDIHDEVDANQLESPLPPIPPLCDHNDCGGCWKGYPQSRFPNWTPGQVLRSGIAEAVHDYDTTDPCIIHYVNVDTGGFFTDADKHFVREGDVDVFWNEIAHETRPSNLRVRALFIQNLSGPVLQMLGAKYNIEPFFFSSSLSSIPSRFQEEVRPGKGDHITITLSFIRTVRATSSKPLFPSNHNLSSTSSTDLISLEQMINTQAPLRIGEDMHMLALDLLSVHLIRRNDGLGSTIISYHGHDENATSAPYLHERLRFAGQSVYWQSIFQKSPDPTFVLLTFIWHAMYAWDEALEKLYGHICWMESQIMRSSDMDLTRDLHTIQAHLLHYSSLLEDFRKSVVFVNDTLNPAMDSLPNDERLLSRKLLEKECNNLLIEVERLEKSRTMQERRLKNVMNLVFSTVNILDSKRMQDLTEAAVRDSAAMKQIAYLSMIFLPASFVAGVFGMNVKELSAQTLGTLPHYFAAAFPLTAVTVWIVIAFQSKHLFKNRETSSFWARLAWPILMFQSLFSKSKKTRTSLSSVNVLNQWNTNQQRRRRSTAAAGAIYELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN98</accession>
    <name>A0ABQ8VN98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycoside hydrolase family 18 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_758801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="9">
        <location>
            <begin position="1"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4497853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="40759" checksum="72A10AF46E6DC59D" modified="2025-10-08" version="1">MGYYPYWVGSAFPPEQIDFTKYDWVDFAFASLNQTFQLSFEDASCPDLLRRTVAAAHAKGKYVKASIGGWGGSQYFSSAVSTDSNRRTFVQEVIRMIQTYNLDGVDFDWEYPGHEGLPGNQVDPADSSNYLLFLQLLRSSLPRMKKITAATSQTPFTDSNGQPMKDVSAFAPVLDWIMIMNYDVWQSSSTPGPNAPLYDGCHNSTQPQASAASAVKQWSQAGFPLYKQVLGVPYYGYLSNSNATRLRTRASSPSVRLTADEGADEGSVTFRNLVKQGALVASPSSDGRRRIFTASSGFNRYWDECSATPFLRSQTSRQLVSYDDPQTLHMKGQFVKKMGMLGTNTWDMSGDTPQNDLVVALMDGLFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPC4</accession>
    <name>A0ABQ8VPC4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_939912</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF133">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="30345" checksum="E822DE4D57DA0CA5" modified="2025-10-08" version="1">MSNRLAQVSGHLSNTYGRGLLAGEVAIITGAGQGIGRSAALIFANEGAKVVLSDIDAKKLAAVEQEIKSAGGESISVAGDVGADDFPKRIVDATVAKYGKINHIVNNAGFTFDKMLHTTPDDTWDIIMKIHVRAPFRLIRQAAPYFRVKQRENRSIINVSSTSGLHGNVGQANYAAAKAAVIGLTKTIAKEWGPFGVRANTVAFGLIHTRLTAAKEDGATMEIDGKKVALGVPGAKPPTDAARQSGEAYPLIPLKRGGNADEAAASMLFLASPLASYVSGHCLEVTGGAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPV2</accession>
    <name>A0ABQ8VPV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dynamin GTPase</fullName>
            <ecNumber evidence="1">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_901059</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF212">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="9">
        <location>
            <begin position="255"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="8">
        <location>
            <begin position="836"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="927"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="946" mass="105686" checksum="1F083AE33137CF61" modified="2025-10-08" version="1">MYCFIHRHFPSILSNRKAVTYGLKTAKAYSTMKNIPSRRRIWEQTRAYNRSQSTFLAAGSLRSSSATPLAAMRRIHARSLSYSSIPRFVARAFRVPIAGAAVGAGGLGYAEYRFEEFRKETQSWMNAVQDSAVDLFDSATDRVNKARTRVSGIKLPKFQAPQFLKDLFTEGDQDKTGKNKGEDGKRDKDGSSDSKQRPPSDNATIAALLAATMSSPSDSKTGNGQLESQPNGLMNLTKKLIEIRSMLLSIDQNDSLKLPSIVVIGSQSSGKSSVLEAIVGHEFLPKGNNMVTRRPIELTLVHTPTPPGETPSEYGEFPALGLGKIHSFTDIQRTLTDMNLAVPASEAVSNDPIDLRIYSPFVPDLTLIDLPGYVQIASLDQPESLKEKIAGLCDKYIREPNIVLAVCAADVDLANSPALRASRKVDPLGLRTIGVVTKMDLVSPEEGAAILGGNRYPLHLGYVGVVTKAIGKNKSERTGEVVKRREDDFFGAHKGIYGSGSLMVGTSTLRKRLMEVLESSMASSLHGITNAVQLELEEATYQFKVQYNDRRITAESYVAETMDVLKARFQTAKAEFRKPIIREKLKMMLDDKVMDVLEQLYWLDKRAKELGDLAVDSRVKGPEDVDSYWKHKLDAAGSLLTKSGVGRDSTLLVADGLRAMIDSIASGEPFTYHSRAAERLISFSHDILRDRIGVAADQVENCIKPYKYEVEVEPREWELGRERAIGLFEKEIAMCEGKLKDIRKKVGGSRRLGALVGYVQILEEKEKERKERKLRAVTANSNDDAAEEFEETLTESYRFPAAQILDAKHAMLYTDRISILKLRTVALRSKRCKAGPDNDVFCPEAFLNVVADKLAYTSTMFLNIELLDQFFYEFPREIDSRLLYDLDRKEIVEFARENPIVRRHLDLQDRKDKLEEVMKQLNSLSTLRADPQPKPRRNRGLFGGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ00</accession>
    <name>A0ABQ8VQ00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_979041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="683" mass="74577" checksum="C4A2C5C8BC2EDBD2" modified="2025-10-08" version="1">MVDSLNLESVFSSSLQKQCVPTLASTNKHPEDMASFSLVDIQDHSTPHMKTRVAVRDRTPHRFQVIPLKDAKQTHSMLQLSNKTTPVSNSTVRKGLKDVTNFQETTPRGALAVSDGGKLNPCPDLQNELKLSAPGLVKDVQARSPSFISRTLQHRTSLKPETPSVTPIPPHKISQIGSKCTSITAAIQSLPVKPLNIVKRGDVSGPPLTGIRPPTVRPAAIRDVSKPPTATSAAPLRTGLATVAVSPFPAFDFLNSPSESTSTISKHRRRSRSNNAPLTSKLPTARTRMNPEHFEVRELSKPGHDPKVPTTVSNPATPTICQHHHKSPTPNTTVTTLSTPNFASKDIVRAPSATPTLRKRVSGDIQMTTESVNRRCTSKYLKSSSTAAASRENLSEFRIPSSKLKLAFHPHTLDPVLLKPKHGITHSVDIVNLNPRLLQAPRIRQYQDVRNVFPQCVEPPTAVEKSQSSESVAVTPSPPLGRRSVLKSEIPSKRHAIYTRSLYVGKAEKDSSNYLRALEGMITSHSSLHSQVTDHEEVSTSSDSLGSILQVYQDAVNDEAHPHSRSFSVGLPTSHSEPTLYDINVTPLAVACTGITPSDENQSKFPVASVSLSSLGSVYSQDSWASGERQDIQLSIVAGIDAIIFSEHKPERKTGHHPIVWELLEKLESAQRTWLWDTGSDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQN3</accession>
    <name>A0ABQ8VQN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_916187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="7">
        <location>
            <begin position="238"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="301" mass="34256" checksum="9FD21AEDF2B80324" modified="2025-10-08" version="1">MPFVKKIKSGAYFSRFQVKYRRRREGKTDYYARKRLTTQAKNKYNAPKYRLVVRFTNKDIIVQIAYARLQGDFILAAAHSKELPRYGINHGLTNWAAAYATGLLCARRALTKLGLADKYEGVAEPEGEFTLTEALDEEDAPRPFKCFLDVGLKRTSTGSRVFGAMKGASDGGIFIPHSEKRFPGYDPESKELDAEVLKKYIFGGHVAEYMESLEEEDDERFKKQFATYLADGIGSEDMEEIYTNAHAAIREDPVFKPTEKTKDWKAESSKYATPRLTHAQRQEKINARIEQFRAGAGDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQX9</accession>
    <name>A0ABQ8VQX9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_817660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="167" mass="18814" checksum="DD9133AA8F32DA95" modified="2025-10-08" version="1" fragment="single">MFSMNFKFFCTFLVRSTTSEAGKRTSKFKRIDSKFEKCIYTSSRFEPFSSSVPPQSNHPSQSVSRATVVGMAPIMTRFFQFALVCVVVVGLTTTVCASPIPVPVYVLRVISSITDLILSSLGLVTTPHSRMRPDIGVRDAWKELATTKLRIPSSQFRWKELFLLTEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRF2</accession>
    <name>A0ABQ8VRF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_865744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986:SF1">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="27894" checksum="E2C5B1F41C021B33" modified="2025-10-08" version="1">MIFAHPPHPSELRRKENSYTFTIPLLGSSSSSPIRDPHDIPTFDSTSLIEPKTPILYLPPLLSSLPANFPRSALPHEHPPLVTETRLPDIDPASLSLHKALHRFRPLDSLYSETPYAQAFNWHELSLPVDEEREWYCVVFRSKRKAGSDGGSLYEADKKAHEEAVGNGGLILYWYGIPNQQTGMNLATCIWQSRKHAIAANSRPHHIRAMMLAKDSYEVYDLERYVLQKVAGVTGVTVQPFVAGEVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRH9</accession>
    <name>A0ABQ8VRH9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_755963</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="54"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="205" mass="24295" checksum="18058DC3E370237D" modified="2025-10-08" version="1">MDILPESNDQYGTKQYWNQRYAREDDDASFDWFKSYSEIADILRSLIPEKRSRILMLGCGNSKLSEDMYDDGYHNIVNTDYSSIIIEKMKQRHGDARPQMEWHEMDVRDLEFDDSSFDVAIDKGTMDAMMTAKGDIWNPPQQVVDDCTREVREVIRTLRKEMGVFIYLTFGQPHFRKRYLTVPGTKLEIRELGEAFHYYLYILRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSQ6</accession>
    <name>A0ABQ8VSQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyrimidine 5-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_817266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="250" mass="28753" checksum="3B0B21ACE23A7A90" modified="2025-10-08" version="1">MTIQDERQITVFFDIDNTLYSTSAKISQAMGVKIHDYFVKLGLSDEEASDLHHKYYTQYGLALAGLVRHHGVDPLDFDRNCDQALPLEEMISPNPIHRKLLEDIDRSQVRVWALTNAYKVHAERVLRILNLRDLVEGIVYCDYEAKDLTSKPEPAYYRKAMSLASVIDPSKCYFIDDNWRNVQAAQKIGWAHCVHFCERGLEHVEGGKLTEISLTAKANVDSKQEEQPDIEVISELEELRDVWPEIFKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VST9</accession>
    <name>A0ABQ8VST9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_754511</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. LDAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019363">
        <property type="entry name" value="LDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390:SF0">
        <property type="entry name" value="LIPID DROPLET-ASSOCIATED HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10230">
        <property type="entry name" value="LIDHydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32858" checksum="723D10AB6C230043" modified="2025-10-08" version="1">MDVPSFLQPQTDSQYANSVYVHSIFQHSKALGVSKTIWWPSADPSTVVLFIPGNPGLSEFYIPFLSALYHQSNSLCILAQSHLGHTEEATAFIHNLAAQVSAAIEGLDALKQTYPGKKFIVIGHSVGSWIASQVLKARPSEVHSVFLLFPTITNILDTPNGRSLSWAFRPPFPYIISKFSLLLRPIFSRILSVLFSEWPKAQLAVLLRLLHSSSCIEACLSMAHEEMNTIRELDVKFLETYRHRIHMYFAETDGWVGNNKDVILRSFNPDRDSVKIVHGDHGIPHAFCISKCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT60</accession>
    <name>A0ABQ8VT60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_893452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="201" mass="22404" checksum="502C787440323141" modified="2025-10-08" version="1">MEETMQVDDFGSTSAFVSQAPVQSADSGNIPTPLITREIQVKVHIRRPERDSWVYMGRGLVSQEVIGHSSRVVVRAMSTNKLLTQFGEGTDLQAEKRGNFVVVGCVEDSGVVSWSLNALNNSETLRLLASIELACYKCKNALTDPRKAGRDRKKTERIIKDDRRRRHRRRKDQEALIDAFAKSNISNEATEMSTDGVPAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVR3</accession>
    <name>A0ABQ8VVR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_914039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="177" mass="19855" checksum="73147D8CF442D9F0" modified="2025-10-08" version="1">MAAFPSLDTLSTLRNVPTLPDTDNRRTIHFFYVHPNSPFPLRQPLTFAISPQVVHHPRPWISSFLIAIQESAYQPASVIAPTLACLTVDEIGRQMEVIMLSMHQGPPYAIHQCSDSSTCTRSTATCYSTTHAFGIAVNSEGHLCDVEVGDQWVIWNWFRSKACTHPITSLQQYDPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW08</accession>
    <name>A0ABQ8VW08_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_914077</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ZNF598/HEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16615">
        <property type="entry name" value="RING-HC_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057634">
        <property type="entry name" value="PAH_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041888">
        <property type="entry name" value="RING-HC_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23202">
        <property type="entry name" value="PAH_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23230">
        <property type="entry name" value="zf-C2H2_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="96"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="374"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="667"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="830"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="688"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="727"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="806"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="841"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4500506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="865" mass="92328" checksum="D41B43A4D9C5661C" modified="2025-10-08" version="1">MSTVVTSTNTQQTASSQPQSREHQYRGGRGGKAQGNKGRGRGGRGGREINNGRETNVIKNQDSGAKDGREKTDLVEDTTRVVAAAADDVDSESDVCWICAEPVIYYSLSACNHRTCHVCALRLRALYKKDVCTFCKEPQQDVIFTTSADKPFSEYAEELSSSIDGSSPKFYDPKLRVAFETQEMMTESLILLRFNCPDNECDYIAKGWGDLKMHVRASHGRLMCDLCIRSKKVFAYEHVLYTYQQLRVHLPSMDYSGRQRPGKKSNATLNPPEGGIHPLCEFCRECFFSEDELYAHMRERHEECFVCKREGVRDNYFAAYPDLESHFSIAHYACTHPECLQRKFVVFGSALDLQAHMVDEHGASRKVVGIEFASGAGGGRDIGSRNNRDPPPRQQPPPLPPPAPSQNQSRRRQAFGGALTSGDATPTTSSPAPVNIGPGLGISRRSSPTANADREDTFVDPAVADRHSAFLTLLSNLAPNPSSALIAVKAAARGYRAGESTARDLIGIVWNVLDASQNKGSGKSGTEGLEPTARVINSFVDLLEEDEDRDGIEEKDKKSLELLREWKGFEIEQRRQFPDLISSATASSSTGGYAAITSGRVLNAKHSTHTSYNRGGSSTRRVWDRVAQAANSGSGARTPSAAGPSGSLVPGSLAAVNAKSVDKFPPLGGGSGVGSSKAPTGSRKTPWAGSGSSSSSAVNPSATSAFPGLSSSAPSSSPAPLRPFSVPASSMTSKTRTNGTPPPKLSTAAFPGLPTSENKREKVQVKGNVSLRNILGSTKEVPTSKWGASGGNGLNGTGALPAPGSGSATPVTTPGPNEVEELVEPTEVEAGEGLSATGKKSQVHNKGKGKGKQKQMLFTLGSFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW56</accession>
    <name>A0ABQ8VW56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PEBP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_810232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047047562" description="PEBP-like protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23298" checksum="2F3F73844AE586D3" modified="2025-10-08" version="1">MQLISIKVCSALLLGFLSLTKVVSAPVRATSVGDSPFSESNPASPDMNTTTPHSLSVSGRSGRPYLHRQSEQSVQAIVEFESNVISTFPPTQATLTALHVILRNTIGIYYPHEPEAPEIELAVKGPQPALQKLQFKVLFSDPKGIVPNEQVYQVLMRAPWLSEPGLRDGDVTALSGYVVANFGTVLRFQNGKGQFLTGSWDPREKSFDLNRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWC7</accession>
    <name>A0ABQ8VWC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_808479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="251" mass="28242" checksum="BBE854553DF6385E" modified="2025-10-08" version="1" fragment="single">MHRDDHGSRMDITMPVHRDPPQTQSIPYQTPVSVPFRPPQHSTAYMRTNSHATSPMDTGPGQMINNFSSPHSIHSPLHHSNVPSLPSFPSAPTLPQSVSETWHHRIVPTFQNLTHNFTSQNLFNYRPLPPAPSSNNFLPESFTPIGSPPFLPINYVRSPVSVPPASVRLPSRLGSRMANHPAIERTPSRIMHQPCPHRIVDLDHISASAQLIPETQSAPAILSEFPRDHYHHLPESNHQWFPNPLRVQESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX73</accession>
    <name>A0ABQ8VX73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fungal calcium binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_279637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.120">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045206372" description="Fungal calcium binding protein domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="13191" checksum="3525B6495BDDE71F" modified="2025-10-08" version="1">MSSNMRTIALAAFLASATIMASALPTDGQMPQARAAVVKMRQEPAPNSTETTTTASTTPTSTSDSASCGVSDIFDCVKGLEKTVTSCATAASDWGADISKDKQCLEDAESDIKSLPSQCLGCVKKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXB5</accession>
    <name>A0ABQ8VXB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_913569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="30290" checksum="798CF09AC21AA6CE" modified="2025-10-08" version="1">MVPYNITYLSGDFPMDHSFFESLSELKNLETLRLHGSARNGIVFPPLPTPLVLHRLQSFEFRSDIHTPFLLDSIVTPSLRILVIARQINEKTQKSLCSFIQRSCCRLSAFSFLNASGDDLENRFLKEFLVSPYMEFLTELNILSSNADAVFRILVGGNSSEPVLPSLNRLWISTSWCSGDLLIDMLECRAHNFHPPTSTLMSEPLFCVKHPHPSQYLFIPVSGISLCIQVTRFKSCFEDVSMWFESHDRAHWSMFTASVYWEPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXF1</accession>
    <name>A0ABQ8VXF1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_807984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="333" mass="36892" checksum="89224B53A6DCE02C" modified="2025-10-08" version="1">MTLPLRKIGNAEVHPVGFGAMGISAFYGKVESDEERFKVLDAVYASGCRHIDTAHIYADSEALLGKWFKKTGKRDEIFLATKFGISPQGPRGDPEFVKEQFATSLERLGVETIDLYYQHRPDPKIPIEITVGAMAELVKEGKVKYLGLSECTAEDLRRAHAVHPISALQVEFSPFVLDIESEEIGLLKTARELGVTIVAYSPLARGLLTGQYKSPDDFEEGDFRRTVPKYQAENFPKILDVVKQIEAIGRKHNATAGQVTLAWILAQGDDFVVIPGTKKIKYVKENMGAADVKLSAEEIAALRKIAEESDIPGNRYAEKHMQIVLVKTPPLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY46</accession>
    <name>A0ABQ8VY46_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyanate hydratase</fullName>
            <shortName evidence="5">Cyanase</shortName>
            <ecNumber evidence="5">4.2.1.104</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cyanate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Cyanate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cyn1</name>
        <name evidence="7" type="ORF">C8R41DRAFT_873283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>cyanate + hydrogencarbonate + 3 H(+) = NH4(+) + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:11120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29195"/>
            <dbReference type="EC" id="4.2.1.104"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MBF1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.104" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00559">
        <property type="entry name" value="Cyanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1160.10">
        <property type="entry name" value="Cyanate lyase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00535">
        <property type="entry name" value="Cyanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008076">
        <property type="entry name" value="Cyanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003712">
        <property type="entry name" value="Cyanate_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036581">
        <property type="entry name" value="Cyanate_lyase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048564">
        <property type="entry name" value="CYNS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00673">
        <property type="entry name" value="cynS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002773">
        <property type="entry name" value="PRK02866.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34186">
        <property type="entry name" value="CYANATE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34186:SF2">
        <property type="entry name" value="CYANATE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02560">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21291">
        <property type="entry name" value="CYNS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001263">
        <property type="entry name" value="Cyanate_hydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01693">
        <property type="entry name" value="CYANASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01116">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55234">
        <property type="entry name" value="Cyanase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="163" mass="17891" checksum="9895059D8D71FA1D" modified="2025-10-08" version="1">MSQSASIPTNSAPFSALPSIHTLLLEAKAKKGLTFDAIGKAIGKDEVWVASAFYGQAKFNAEDLQKLSEVLDLPHAELTAGLGEHWFPYRGLGSAVPTDPVVYRLYEGIMVYGHPIKALINEKFGDGIMSMIDCYVKVDKKPDPKGDRVVLTFDGKFLPYAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYF1</accession>
    <name>A0ABQ8VYF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_27750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347">
        <property type="entry name" value="RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347:SF1">
        <property type="entry name" value="RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="5">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="271" mass="30483" checksum="4B5387B1E572FF96" modified="2025-10-08" version="1">MSDTEDQKQCRICLDGADAEQELGRLIRPCLCRGTISYIHVKCLQKWRNSSQNQSAFFRCGMCGYSYRFSRTRAVGIASNPVIVGCISALIFTLLTLASSYITTYLLAYFQGPSSSSFYITSSSYWFYDPTEVIHDLVRAALRILQDEEFDTETFLSRGQTPGTSFSASLNSTEGANFLKRFIQRFVIGLPLIGASSLIHMMISLPFIGPVHWLARFRGRRRNNDRDISAIIIVVLIVLGAVRALYAVYQLTQSVTKRLLLRAEDAILEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYK1</accession>
    <name>A0ABQ8VYK1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_786113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="691" mass="74357" checksum="FCCCE0668AA14FE3" modified="2025-10-08" version="1">MSVKPGSVATHIPTSLPSFAQTFNSSSLSSYGPDDNSLPPIHDFSRVERQSILSRHRSDEDAARAGRKRTHAEASSSRNEDNQLASDRDSPSLTRVKEEPEQDMLASPPPPSSDSTNSNIHDTSGAPPPSSINAPKSKKRRVTISGAPALNTDVRIAPDQTNNSTPISPVVIGFTVQRDNPSEVEQIRSMLTVKQQQQALIEQRRGSTSGIMSPTIAAGPSAAAGEGHPKSSLQGIRSVRRSPNSGPSNRRHTVVIQAGTNRPPSPNSNIVHTQPPPASVAPHSLPPPPISFARRRANQIGGGKKKPADIMISPRDAHTPDQFAPSIQSAPPIPHAGQQGGGLVGRFPMALPRLPSVMGDNVRRTVGGNVPPTPTRFSAQRMAISQGVSHPITGISGRSPPNASVPISSTLVPSTPSALHNPGYTGEKSAFLAPFESFYDALNDSKQLKTWLSEQLQKSKILIQNLTQQQDKLHETVDSLVEKKVAGMRTEIVGLNRRVEELEDALRVATSSRRPSIEGPASGNKGKQTVRNGNNLLGTSITEGYTFPPIATIDRERLRSESSEHRMSPGWTHDKDSRDTQDSEHGSPVLYESRRLSLSSSRLEPRAQSMESVVRPFASPSLPFREVPSVSHPPPTSSKLPRGGRPLGPGRHHSSPRLPGPVQDSLVTSSPRREESRRSSIVDGSIDDRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYU0</accession>
    <name>A0ABQ8VYU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">VHS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_913184</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14235">
        <property type="entry name" value="GAT_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16998">
        <property type="entry name" value="VHS_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052653">
        <property type="entry name" value="ARF-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="4">
        <location>
            <begin position="23"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="5">
        <location>
            <begin position="187"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="529"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="544"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="559"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="586" mass="62655" checksum="DF56BBAB06EC4A02" modified="2025-10-08" version="1">MLQSPTSSSWTRVSPLEVLITRACDPSLHEPNYAAHIEVAEYINNKKANTPREAAMTIARLANNRNPHISMLALSLLDTLVQSCGYPFHLQISTKEFLNELVRRFPERPPPYPNAIMSRILELINTWKEGICVESRWKEDLSNIRDMHRLLTFKGYRFRDFARPSQSQPTAANANLKSAVELEEEDRAAQSAKLQELIRRGTPRDLAAAQELMKSLAGADPEAKPDYKTQALHEINKLESKVVLMNEMLDNVDMERGEKFVEGDAYDQVAEILRAARPKLQKWASEVDVESHDSESLDTFLQMNDQINSVLNRYEAFKKGDYSFAANPIPAELSNAGSASAGTGLSLIDFDDSTNGTSATISTPTNATTATSNSGGDLMGLFGAPAPAATRPSPLSSLSSLSHPMSNAMPVMESRIGLGLPGMHVGTPTPPIPSTFTPPNHSSPSSAPVFASTPPIGMMHGTGGVGMGMGMNSALGYGSPFGPSGNVGPRNSSPAPAAPHTPNYFSGVAGSGTVGVNMGMGMGVARIGTPSTPQTMQPMNAMGSMQSSQSSQSMQTQSPAQNGSSMSSQPPATQAKDPFADLAGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYX2</accession>
    <name>A0ABQ8VYX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NOL1/NOP2/sun family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_748222</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023273">
        <property type="entry name" value="RCMT_NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054728">
        <property type="entry name" value="RsmB-like_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF30">
        <property type="entry name" value="28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22458">
        <property type="entry name" value="RsmF-B_ferredox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02012">
        <property type="entry name" value="RCMTNOP2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="11">
        <location>
            <begin position="311"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="110"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="205"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="636"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="528"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="403"/>
            <end position="409"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="668" mass="74267" checksum="15D812B4B6A010F6" modified="2025-10-08" version="1">MGHRAKNKQPAPQPLDVKQPHSSSKKLGKRKAESLNDNSNSRPVKRPKDQSESKQKGKKKKKKVLVDSDAEGSADGWEDVADNVELKIHAKSLFSTNDDEELDELGMDEFSDDELRGPAQAFDFGSDAEDNEPEVIIGKSKKSKQSERPAKIIPTASDNSDSSDQSDEEEERITMANMVARSKALDEQAAAEDALDFEEMQHAAFNEEDDDDDLDMDEDEEETDGEPFRLPTREENEAESKAGGPDVHVVQRRMRECVRVLGRFKKLAEKSRARSEYISQLLSDISSYYGYNEFLAEKLFQLFPVAEAIEFFEANEVPRPVTIRTNTLRTRRRDLAQALINRGVNLEPIGKWTNVGLQVFESSVPIGATPEYLAGHYMLQAASSFLPVIALSPQPNERVLDMASAPGGKTTHIAALLQNTGIVFANDANKARTKSLSANVHRLGCKNVVVCSYDGREFPKVIGGFDRVLLDAPCSGTGVISKDSSVKVNKSERDFTLLAHLQKQLILCAIDSVSPDSKTGGYVVYSTCSVTVDENESVVDYALRKRPNVKLVDTGLEFGREGYTKYRGKIFNPSLSLTRRFYPHVHNMDGFYVAKFKVEKRGKISKASDSTAEVGLTGIEEGEQIASEKEKIAFDDDEDRPYIEESKRRRMKAKGLKPPPRTTVKIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W062</accession>
    <name>A0ABQ8W062_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_913292</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="181"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="300" mass="33203" checksum="B600954F55B4253F" modified="2025-10-08" version="1">MHTNTPAVARRSRSPTPDRSSRSHIFGRPSPRPVRTYGRKSQSRLGPNTPSSCRAVSTPSVPSHRNRPLASSSVPSTYHLLSSTLDYEEPVILPATPPHDSTPTPCPPNTSTREVNNLNLESDDDDELVFISMNPPVELKPLQDVSLNEKLQTNPAPENALQNAQTRIQALNDVIKERNNCPCCLELMLQPFILSCGHTFCKDCLLTMSRIHLRAKYNLACPSCRTIQGHFTPIPNYSIQKSVDDMLEIKGIPTPTRQPLQWPHAFRSGPVTFPFPRRNGTYPTAASAAAPVPFPISIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W063</accession>
    <name>A0ABQ8W063_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_863266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047153">
        <property type="entry name" value="TRIM45/56/19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462">
        <property type="entry name" value="BONUS, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462:SF229">
        <property type="entry name" value="TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="135"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="243"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="31488" checksum="24C0CF7350A5AFF9" modified="2025-10-08" version="1">MPPTRLSRRESIVEVLQSGPSTTGPSSTTRTSKNRAPKKPLVLHPDVIEISDSDDDPFAPPAPLMKRKSSRELQLEREVKKLKQENELHKNKANSLRAEITSVQDKLTHLLAAPSHASSSKDHMPISDVEDSVTCEICTMKMWTPYILECGHTYCQSCLQDWFSTTLAQHMAAHPNYNINQPQHPYGADMYAAYPGFAQHHYMHLLGAATPQPHYTCPICRKQVRNPPVEDFNLKKIVRAVASVQGESSPRKEKAGSGRRKGKAPARREDPWSGFFRIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0U2</accession>
    <name>A0ABQ8W0U2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_2825</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="356"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="674"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="674"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="702" mass="79197" checksum="044B8C2F0ED2A359" modified="2025-10-08" version="1">MSLLPVRPRARSSSARPQSTTFKGKTKSNLASIPPDVTELTDSSDEDCVVAKESSRDVTRSGHTLPRKQSTPKPLGASASAENIPPSSARRESKTNMFPPFLPSDEENVPPSRNSNLPSIIEDFVVVDLVPLKHPEGDHVEENQLMELQAEKNAQLSMLSQVLELVPDVQPEYAEELILQHSTTRQGEVLEAVIHALFENSAYPKIDKKGKRKSTEQHHDEGGHKKPRFDEPDYSRLDREYKGGVHYSDLSIEHLMVDFPDIPKPYIRKTLYANKSLYVPAHLYLREEQQRGPPFTYVPKKTLYKPSSKGKHRALEDAEFDQERAWLLEKLRGDDVKMDGAVAERVNQQEYEECGDGIECGCCFTTFPFDKMIQCPDAHLFCSDCMSSYAENLLGAHNINIVCMDQSECKLLFPVSELRRFLSDKLLELYERVKQRKEIEMAGLEGLEECPFCEYKCVIENPNEKLFRCGNEETCGAITCRQCKKIDHLPKSCKEMEEDKVLDGRHLIEEAMTRALMRNCPHCDKSFVKEDGCNKMTCPHCHTLSCYVCRQRVTGYDHFNQSNPGAPGSSSSKKCPLWEPVESRHAQEVKAAAEKALEDYKRDNPDVSETDIKVDVPKFPGHVQASNAAADPLGYGLPGMPRNNPYAPMAIQPHLQHVNNLLRHRAAVYAAALPPPAPHPPQPPAPVPAVRVQPRGHRHRWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1F4</accession>
    <name>A0ABQ8W1F4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_862975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="30392" checksum="4949800FEF613715" modified="2025-10-08" version="1">MNIRDKTFYSDFKIFKVENVLFKVPTDALTAESEVFRDLLKLPPVPSNVEGLSDENPIHLEGVLSNDFRQLLRILCPRFKSTQVLSFTQWTSVLKLADQYMMDSVRSHAIFIMDQQSDFDPIDKIVVARRYSIKSWLTPTYNKILQRPQSFTQHDLERLGSDTVLKLVALRDRLKPMENSRFGSFGLWSLGTKREAISVDFTEALEETLSDCYEIDSESKQSASALTVNAPTDMFIFAAEPSGIPATSATPTRRFTGLRNARAGRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1T0</accession>
    <name>A0ABQ8W1T0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_807998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="184" mass="20489" checksum="F421F1A3511D6675" modified="2025-10-08" version="1">MLLFDTPFVRRILDEHPISQIVSVLGMVIIVWYLYAGDGPLLHRARDIQGVGVLVMLPLGFKFILLYLLLCYVRTIYYAIPSSPPSDSHRISSATGILPTARNPPCKSRVKKSILPLPVQIELPVEGWSITVRFSSSQPHVRLSYNFKFGKELGTIINSSLDPPPSCQDSSAASWKQDRRGGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AXJ2</accession>
    <name>A0A9W9AXJ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_215447</name>
        <name evidence="5" type="ORF">C8R41DRAFT_574021</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000004">
        <property type="protein sequence ID" value="KAJ4492804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AXJ2"/>
    <dbReference type="OrthoDB" id="2971942at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040979965" evidence="3">
        <location>
            <begin position="22"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4492804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="258" mass="27509" checksum="FC289CCA801CBDBD" modified="2023-11-08" version="1">MLVSLFSLFLTLSRYIGFTKGLQITLENTITLGETTTISYVTGSSDPSEWLLRNVYANGTTQIGGVLSGTGSVSFSFQLAGPHFLQAVAYNDSTSTATSQPFYTGNLFTPVNSSSTSSSSASATPSASCPSASSTPTTSPSSSTSSSSSESGAIAGEVIGVLGFLAALIFFGMWFRLYRQQHRKPEFAQTFMQTSGNNGNGHGVVLTPVIVTPYDGPAPTQRIASWMRRLYRPSKYLDEADMKEANIGDDSDTTRSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DU50</accession>
    <name>A0A9W9DU50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Septin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_471829</name>
        <name evidence="7" type="ORF">C8R41DRAFT_752262</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000010">
        <property type="protein sequence ID" value="KAJ4486725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DU50"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000238">
        <property type="entry name" value="Cell division control 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="28"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="317"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4486725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="384" mass="44364" checksum="6F68D46AD3E8F3BE" modified="2023-11-08" version="1">MATTAPPTFNDVGIANLPNQRHKIVAKHGAHFTIMVVGESGLGKTTLINTLFSTELSPPKNYSRRHHKQLDKLTEVEIIKAELEEKQFKVKLTVIDTPGFGDYVNNRDSWSPIVEFIDDQHEAYMRQEQQPQRSEKTDLRVHACLYFIRPTGHTLKPLDIEIMKRLGTRVNLIPVVAKADTLTQNDLFLFKQRIRDVIQAQGIRIYTPPIEADDEGADHARVLTEAIPFSIIGSTEDVQTADGRVVKGREYLWGVAEVENEAHCDFKKLRSLLIRTHMLDLISTTEESHYENYRQQQMETRKFGEPKVKKLDNPKFKEEEEALRKRFTEQVKSEEARFRQWEQHLIAERDRLNKDLEMAHSAIKQLEAELDNLQVGYNRGSGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVZ9</accession>
    <name>A0ABQ8UVZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000165">
        <property type="protein sequence ID" value="KAJ4463453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="501" mass="56953" checksum="1DD7E77950022219" modified="2025-10-08" version="1">MPSPATPDKVNTENNANKKAWCDTSQSAHQSPGHSLPSLRKVPSATRNLSRTPLPRGSQLCNLLIPGHASEEEELGPLHPIPQPHFLCALTDPVPRTESDPSDPFVDHDIPITGPPSPEKNLSNLLAPSLEKERERKQIDQSDENPHLQPVPALELEQPSDIEAWRVFTQNTGQFERIILDFPFLYQGHSDETICSIQDQSDKWVAIMPINGGRYLFSHSRDIFDKIESTLAEAGCSGQILPPEVPELPSTAIVNLTKGQSMANTNTAQDSFGPPYAAFLSFDSFADWDKILRQQSFAKSKLVAFHAIPVINKLQKWVVGHFWTTVKRYNDETKANMMFVIKNYLFHSNDFRHLIQLYSTIKGPLDEQVTALLDMFDLRKQEYEFKKNDASQYQWVLFAAPTSMNPNLAIREFKEEQICSFIRSREYRGGIYHVKAAPLYCAMCKSWTHNYFACYFATSPDWHGPKIEERIKVITEEVKKDRRRAQRGTQAKSNGHNHSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXM2</accession>
    <name>A0ABQ8UXM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_804071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="62177" checksum="197A931FC29FAAE8" modified="2025-10-08" version="1">MTSTSISDFSIVSDFPSFSQPEEASETSISISNSYILEPLPSSVKDLLKTNEAPLHSKLLQSNLHDAESMLFDLNVQLEKMKAEIALFTVKRNQLMTMIETYRSILHPIRRTPPEVLLEIFSYCVEFVDTDHPKICQNLDSLDTKQAPWSLAQVCKYWRFVVLECPRLWSSLSLDLARMEHKDPAKAQELEYNAIALLSHYLRRSKDCPLTIAVHSTRPMHPIVSLICSHSGRWSNVLLSLPPEGFRLLSTIKGCLPKLKALHLRNVECLENIWNAMPVIDAFEYAPNLRMVRAYEIPNIASKLLLPWDQITHCMNNFPAGDVLFRDSLNRQNMDILTKGVKLRHVALFCSGYGPSLSLKNLKHRFLTALTIDLIRHSNLYLLTQLLNALTLPSLASLRISVSSKLRVRPNVEPIVRLLERSDCALVKLRLKGFETDMEEDSHFRSLLYLIQSSMQVLCLEYFPTSLLSALIATEDQAPFLPRLRHLRVSGVCSPQMDQLLFLKMLESRMKYTKSMVLEISSHFILTNQEAQRQWDQLDIITSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYT3</accession>
    <name>A0ABQ8UYT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Laccase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_93101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000121">
        <property type="protein sequence ID" value="KAJ4465860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="98"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="211"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="423"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4465860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="505" mass="55967" checksum="2B7088469781A0EC" modified="2025-10-08" version="1">MDCSCCIIICSRGVYHKLASSTKLPMFLINIVFGFCLLLLPTRLLLVNGLEIVKSHPRDRIWHEKTDHHDQIFIVNKDIAPDGFQRSTVLAGRTPQDASFPGPLITGRKGDRFTINITDLLTDPTMDRSTSIHWHGLFQKTTNYADGVAFVSQCPIATNHSFLYDFGVPHQAGTFWYHSHLSVQYGDGLRGPIVIYDPEDPHQDLYDVDDESTIITIADWFHLTSLQLLAALVVPNADATLINGKGRYVGGPDTPLAVINVEHGKRYRFRLIDMSFDAFHGFSIDNHNLTIIEVDGINTLPHTVNFIEIYPAQRYSFVLNANQPISNYRIRALSNTGVGAHNFTNSVNSAILRYVGAPEEEPQTSQPLSSDEVMFREGDLHPLENRGAPGNPYPGGADLVLNFTLGFNADMVLFSMNGVVFESPTVPVLLQILSGAHHAQDLLPKGGVHTLPPNKVIEINFFGGDAPAGPHPFHLHGHAFDVVRTSDSSEYNFKNPVSFQSNSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V020</accession>
    <name>A0ABQ8V020_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_927236</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000153">
        <property type="protein sequence ID" value="KAJ4463773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24094">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="736"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="761"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4463773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="780" mass="85913" checksum="DB616475B64DBCC6" modified="2025-10-08" version="1">MAVVGVDFGTLASKIGVARHRGIDIIANEVSNRATPSLVAFGPKQRAIGEAAKTQETSNFKNTIGSLKRLIGRTLNDPDVQDIEKKFINAALVDVQGTVGVEINYLGERQKFSATQLVAMYLGRLRDTASAELKTTVSDIVIAVPGWFTDVQRRAILDAASIANLNVLRIINDTTAAALGYGITKADLPEADNPKHVAFIDVGHSSLSVAIVAYSKGQLIVKSTAYDRNLGGRDIDYALVKHFAAEFKEKYKIDVLSNPKAVFRLAAATEKLKKVLSANAEAPINVESIMNDIDASSKLTRDDLEGLIADELSRIVAPIQRAIDDSGLNLDEIEVVELIGGSSRIPAVRARIAECFPGKTLSTTLNQDEAVARGATFSCAMLSPVFRVREFSVSDINAYPIKVQWAPVPSDPEEDTELVVFGEGNAMPSTKILSFYRKDPFDIEAVYAKPENLPGGINPWIAKFTAKEVPLLGQENPGDPVQVKLKTRLNANGILGFEGAYVETREDKDEPAPMDGVEGGEAAAAPPKKKKIIKHEVKFVVGNSAMDKGDVEKLKEQENSMWENDKLVKDTEDRKNALEEYIYDTRSKLDDRYAPFVQQPEKDALLALLTEQEDWLYTEEGEDATKSTYVQRLDACKALGDPIYNRWRESEDRQRSIASLRETLNTYMAQATSSEEKFSHIDEKDKQSVVEKVAVTQKWLEDMTVRQMEREKFRDPVLTTAEISKKRDEVIYFATPILTKPKPKPPVVPTPTGSGAQTPKTEPEPEAKKEAPGPSEMDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V098</accession>
    <name>A0ABQ8V098_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Calcium uniporter protein, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C8R41DRAFT_857401</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Highly selective calcium channel localized to the inner mitochondrial membrane, which mediates calcium uptake into the mitochondrial matrix. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates ATP production, cytoplasmic calcium signals and activation of cell death pathways. Sufficient to operate as a pore-forming channel without the need of calcium-sensor or auxiliary subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer, assembles in a dimer or dimers configuration with two interfaces.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCU (TC 1.A.77) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006769">
        <property type="entry name" value="MCU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039055">
        <property type="entry name" value="MCU_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462:SF10">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04678">
        <property type="entry name" value="MCU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium uniporter protein C-terminal" evidence="20">
        <location>
            <begin position="212"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="348"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ4466028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="397" mass="45037" checksum="DE3E40270A3399FC" modified="2025-10-08" version="1">MFWSRFTGRSTFLCASVKPTRYSLLTYSLRTTLNVKGTRPISSAYLENSKVEHSQFLANASTHSNWKDAVPGNGTTDTEDDELSDIEEGIGKLLPTTSHLFKLILPLGRKGPNDSPIPIVLLLHPSQPLSHTGRLILASLPRISENGPSISFRSTPSTSSQQDSRQFEWSDSIDIGDFIRDAARAAEFSIHITPDASDGQQEQVITVRVPTFADRTRFLRRRLDAINHQLATMEGLKRECDREARKGARRMALGGFGMLVVYWAAVARLTFWDYGWDIMEPITYLSGLSTVICGYLWFLYQGREVSYTSVLDRSVSSRREALYEKRGLDIEKWMELVSEKKHLMREIGQIKEDYEQPRGDKDKGEKDPDEDEADGEEENSNPLHEPEEEKESKRKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0A0</accession>
    <name>A0ABQ8V0A0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_779196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF142">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="453" mass="50366" checksum="7C624FD060A72D2A" modified="2025-10-08" version="1">MADASDLDAAAVADSQVLGVIVIARNGDRVEYYQDPKTYEGGVTETTALGEVESHQLGSVLRSEYLSPTSPSYIDGMRSDLVDNSEIKVRVKNGGEGTVIFDSAIALLQGLYPPNPKNKIVLANDSVVTAPLGGYQYVPVETVEPSNDRSLESWTDCPAFEKHISEFYASDEFKAKEKDAQPFFNSVKDFVFGRPTTLENAWNLYDYINSELTHNKTYAYRLPPTLVETARGLADFHENGVFSDKQSGGIGNIAGRTMLHTVLKALERVAFNDDPLQFMLVETGYQPFISLFHELEIVKEHPELQAIPDFASAFAIELRRGSPPDVRDFLRFRFKNGTGGGFKTVYVYGRHADIPLTEFIYKAKGGVISSNKQWAQVCGGSSFINSELGFVDQITYAATHQTLYTVAFAFMTFIGLFVLRSVFVRATKATGQKIKNLRAKKVRLEGEEVSWWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0N8</accession>
    <name>A0ABQ8V0N8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-protein ligase molybdopterin-converting factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_860784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="94"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="479" mass="53554" checksum="E2BEDDF3105A30A1" modified="2025-10-08" version="1">MDNFRSHQAQLIATALAASAATAGLIASYNAYTRRAKRKDLNDEVLRSIQSNGSNFNIQKLQLSNSEDGLSFPSKSSESSGNMYNEELIREQLARNYAFFGEEGMKKVRGGAVVVVGCGGVGSWAAVMLARSGVSKIRLVDFDYVTLSSLNRHATASPEDVGTPKVRCIERTLKSVAKWIEVDARVEIWRKEEGGVLLEGADWVIDAIDNIQTKVDLLKYCTDNSIKVFASMGAGAKCDPTRVQISDISYTIYDPLARSVRRRLRLLGVSSGIPVVYSTEVPSEVKLLPLDEEEFKKGPVKELGAFDDFRVRILPVLGPLPSIFGLHIATYILCELAGKPIVNPLPIKARRKLYERLWKDLLHREEKLIGHTLNRIPLDEDDIALIFEDIHRGRSVIPPHEVPTKPALVRWDLTQPLTLKNCVVMEEKDTVKHIEAWYAWLETNDDEALFSPTGIWGSKVNEVVTKRAKEIESVQEWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0T7</accession>
    <name>A0ABQ8V0T7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer kinetochore protein SPC19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23193" checksum="1A3C5D1B5F2EBD16" modified="2025-10-08" version="1">MKDDLQALQGIYLSPVLESRLELLAQTAEALGLDEPSIIGFNHFIANLSTRRLNLKLSVDRATYVETELRLHLAKLEAELALLRKWTVSLSEVTSPGLETTSVKTGTTETAESLERRRQAIIRKAKEYQAQLVQLNTTNPSSFSTNVSISDLTRLQEQNKEREKEILRKRKKVKAFRGLPAVCSCPVFNLHRNCSSIIPAIPNAVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0U0</accession>
    <name>A0ABQ8V0U0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_854415</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11319">
        <property type="entry name" value="AmyAc_euk_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013777">
        <property type="entry name" value="A-amylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015340">
        <property type="entry name" value="A_amylase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF215">
        <property type="entry name" value="ALPHA-AMYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09260">
        <property type="entry name" value="A_amylase_dom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001024">
        <property type="entry name" value="Alph-amyl_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046810693" description="alpha-amylase" evidence="14">
        <location>
            <begin position="23"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="15">
        <location>
            <begin position="35"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4468520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="539" mass="57695" checksum="FEA35F5AC0A06F80" modified="2025-10-08" version="1">MKYSWAATAVASSSLLANTVFAASADDWTNRAIYQVVTDRFALGNGSSPSCDTSQKTYCGGNWQGIINNLDYIQGMGFDAIWISPVVENVQGTTTEGEAYHGYWPQNINSLNSNFGSADDLKSLSSALHGKGMYLMVDVVVNHVVANPTNTSSVWPETFDYSLLQPFGGSNSFHTQCFIDDYNNQTDVEQCWLGDSGLPLLDLDTENSTVVDTMYSWIKNLVSDYNIDGLRVDTAKHIRQDFWPDFASNAGVYTVGEILIGNVTYAAPYTNGLDSVLDYPTYYAVYDAFTNGTSGNMSAIAEMVTQAQDQYNHGTFYVGSFVENQDNPRIQSTVTDQSIVKNVMTWPFINDGIPILYYGQEQGYQGGNDPANREALWLSGFNTENKPLVTHVKTLNAARKQAISYNSSFLTTKAAFISQSSTSTLAVSKPPFLALLTNAGTSSSASWSIPSSAGLYTGSETLVDVLTCETVTPSSDGSLSVSASSGLPKVLMPAEALSKSGSLCSSQASGSGAVGLKSLGVGLMGAIVIGIVSGMMVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1F3</accession>
    <name>A0ABQ8V1F3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidine-rich glycoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_984513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045475755" description="Histidine-rich glycoprotein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="71401" checksum="8C26919A32BA8A88" modified="2025-10-08" version="1">MVHSRSMLTTVIAVGAASTVLAIPLPPAGIPGGPLTGLAPNTGLPPPPAPVIGSGPIARAETDTRTLSARELDIFVEDEDKPRHHRGENFGVEHHHHHHHHHPHGEEEQIEVEVEEHHPHRHHHHHPHGEEEIEVEVKEHRHDHHRHHHSGEELEIEVKEHGEHRHHHHHHHHGEEELEIDGEHRHHHHHHHHGEEEVEVEVKEHHGHRHHHHGGEEELEVEVKEHHGHPHRHHHHEEFEEHRRHHHHHHHHPHGEEEVEVEVKEHHGHRHHHHGGEEELEVEVKEHHGHPHRHHHHEEFEEHRRHHHHHHHHHPHGEEEVEVEVKEHHGHRHHHHGGEEKLEVEVKEHHGHPHRHHHHEEFEAHRRHHHHHHHHHPHGEEEVEAEVKEHHGHRHYHQGGEEEFEVEVKEHRHHHHHHRHHGAKQFEVEVKEHPGGRHGEEEIEVDIEAVPHNHHHHHHGKEHFEHEHKHFGHHAEHEHEVEIIPVPIPVPVHAPVHEHKAKKEEVTIVVGMENGPAIGGRPLQRMERRRVDEGSPGSASGPASGSSKTPPSTGSSLTPITEEVPSPTGPGVAGATKSSRPTLQRGIPFSTALPLPTQGSLGSRSTPFGDFGDDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1F7</accession>
    <name>A0ABQ8V1F7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000116">
        <property type="protein sequence ID" value="KAJ4466334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="65" mass="6875" checksum="BC3728BFD16FBF89" modified="2025-10-08" version="1">MSKRKSDGFASASEAKKMATAHEPNSSLLSLSTSSKENRTLRRAGPYSSALPVSQGSKPCTNPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1P2</accession>
    <name>A0ABQ8V1P2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Magnesium-dependent phosphatase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_626372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010033">
        <property type="entry name" value="HAD_SF_ppase_IIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01681">
        <property type="entry name" value="HAD-SF-IIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01685">
        <property type="entry name" value="MDP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="133" mass="15092" checksum="C5CA9613091550F6" modified="2025-10-08" version="1">MSTRLPKLVAFDLDYTLWDLWIDTHVTGPLHRNKDTLNEVLDKYNESVSFYNHVPQILHRLRAAGVTIAAASRTSAPTSARSALTLLLVPPMEGSEDEPMKAMDFFDQLEIYPGSKLTHFKTQQKLCRKMSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V210</accession>
    <name>A0ABQ8V210_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000121">
        <property type="protein sequence ID" value="KAJ4465869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="184" mass="19690" checksum="7650E47867AD10B0" modified="2025-10-08" version="1">MSVALPPGLYEIHIPNDAKKKLLAPPSAGETISVGTVQTPHSVWQISGNGAITSFSTGNQTQTKDNPSTVGSNVVTDKAEGMQWIVCGVESTGNNSWTGSIMTNDVTGLFWSIESGRRIVLRNPANESIPQFHFVPASRKAFERGNESIQPSAGKGALEAILTVIILVLYMILERSRGSKAKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V278</accession>
    <name>A0ABQ8V278_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_619703</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4470313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="414" mass="45115" checksum="90877E7BCFA4236A" modified="2025-10-08" version="1">MPKVSARSRSDSSSETNGTGFPCKSCDKTFDRSSDYRRHERTHTGERPHRCTWPGCSKSFAQSSGLKTHMNTHTGAQPHLCGYCDSKFGDPSSRSRHRREVHGDEGTHECPYAGCHSTIKRPKMFYDHVYEKHNVRLTPEEVEACNPYIRNGICPRSKRSQSGRKSARTLVLASTSPSTALEPTYLYADGVESSPILQLPVPLAVPVIPESYPNQSTRNMFYTYDMGSPFVESSASASPSPSSIYGCDDSQSQQGYNSPHTSGTPMGMHDQAFNLNYLTIPHSYAASSSSHSYSTFGSPALTCRSSVASPSLSPSPAPETMETTRLYSTVHHATPEPELLMGFSLDMGQVALGDPLGTLNLKDIERDVQMETFLASLNEGVDNHGMGPENSASSPWGIEQGYGINGMSVVGQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2L9</accession>
    <name>A0ABQ8V2L9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_870792</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF881">
        <property type="entry name" value="FI07970P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="181"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4470532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="353" mass="39000" checksum="C83C17303A0A4B08" modified="2025-10-08" version="1">MPVPVRELPEWPSNVEAHPLLVIDYQLLKAGDETEINRLWEAGTNLGFWYLKNHGAEQDFVAMWGMGEEVFKLPLEEKMKYEQGDEGLSFGYKAVGHYIVDAAGNPDPVEGVNVAKDDALSYPKVSRREYPTVINELMGPVVTPFVEKCVDISNTMIGIFNDKLGLPEGALAKLHGRNDFSASETRTIKAPANLTPGKLAIGGHTDFGTLSLLVNNLGGLQVLPPGTTEWSYVRPLPGHMICNVGDTLTMFSGGLLNSNIHRVVPPPGSQSKYDRWSQVYFTRPADNAPLLPLLESPIISEAFNKLSPERQASLSPGVTSWDWFTRRQKNYRTKNHKGADTWAANRGTEQGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V316</accession>
    <name>A0ABQ8V316_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="250" mass="27702" checksum="AF03A5259B0F0608" modified="2025-10-08" version="1">MFLRQSSAFCRIFYLYIVFAALLGVSLVTSCPLVAVPHLLERSGGDQPKITRPQAFKDGDLVIRLGCRKPGQEEGYMVACVRIMSLLEKDLKFTIFFSTIVGFSTSTVTVAGDLHSQKVIVEQSDIPRSDVSETMQNHCTPRIDQSRLIRLGLGQESLVAHFYRNDTAKKQLVDMFGDADNLLSHTQAMFLKEYGFSWAHMLVINDDLDYITVALICMQMIKGPKGQGGLGCFGGMAQNIPGHESSEGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3H6</accession>
    <name>A0ABQ8V3H6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_924438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF108">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="508"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4472425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="601" mass="67672" checksum="CD532762604E09E0" modified="2025-10-08" version="1">MALSPKFHQLVLENPDFQCSITAVVVDEAHNISEWGTEDFRPEFSRISSLLGHLPAGVPVIAASATVPPEVILDIQDKLGFGRDSECISVSNEKLNVALSVRTLQHPRDSFADLLFLFPSSGATAMDFIQTIIYHSPEYISYVSFEFYHRYISEDHKAIIEEAIANGTLRGTAATDALGMASFGMDFQGIKRVILWIEPCTFNSLVQKIGRCVRIFSELGEAIVFITKASLKRFFIEFNLDSVDGVNDSDGAPAGEEPEWEEPSYRDQTEEEEPRDDDDEVEDDEEGDFIGDFLEDHFEDNGKDAMNSSDNLVEPIPTRCKVTKRKKRNVDVFLGNCSKLPSLFPAPLGSRCCNNCEPLQFPVEAIRLTDPDQLRLPGRAQKSSPEVAEAVRSQLLVLREKLVADIYGPDQYMVTGKMILSDEIINVLAERARFVDSVEALKQCVYWHFAHEFGNDVVLVLADVLANFPDSAQKAQELQQHERALRALLKMEKRDLKNQISSISESCFVAVKNEMDGTQQVYPDYYNIIKTPISMANVKRGNVYESVAQYSSNWDLMFENAREYNEDVSTIYNDTYILQHVFQNALEAATRIHGIILNDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V428</accession>
    <name>A0ABQ8V428_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_587531</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STE7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="120"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4472755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="450" mass="48929" checksum="2844F53B50AACCEA" modified="2025-10-08" version="1">MATPIRKKRNFKALQLTTASAPQIADTAAQPIPTRQAPPASGKKRPPPMTLKAPKLPPSTTSATIEDGNLLTVQSSSTSAPNTAVTPSAKRNTYHTTLSNTLAILDSNAEVKYDLRNEDLKDLQELGQGNGGSVKKVEHTPTGTIMAKKIVLIDAKPSVRKQILRELQIMHDCNSRYIVSFYGAYLADPNICICMEFSDKGSLDGIYKKIGAIDIDIVGQVALAVLEGLTYLYDVHRIIHRDIKPSNMLCNSKGEIKICDFGVSGELINSIADTFVGTSTYMSPERIQGAQYTVKSDVWSLGISLIELALGRFPFAESESDDSDLSDLEGTLSPARPGSMGSIVALSLPPRQKIPKSGTAKKDKRKSKGVSLQGGGMTMSILELLQHIVNEPAPKLTPEGRFPNEAEEFIDSCLLKDPDVRKTPKELLNYTWIEQAKASTIDVEAWANTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V431</accession>
    <name>A0ABQ8V431_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug:h+ antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_775818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4473251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="587" mass="64436" checksum="F256B6DABE054500" modified="2025-10-08" version="1">MNTTTELNHDHRSSDEYNEKHSAKSVVVVGEGQTEGLAKVEAVQRVWGPKSRIAFWVGIALISYVYSLDGETTYTYQTYATSSFNQHSLLGAIATAQAIILACMKPVAAKIADTFGRAEAFTFLVFFYCLGYILLASCTDINTYAAGGIIYYVGYSCLEILIQIIIGDVTNLRWRSLLSSLYSLPFLVNWAVASNISADVLAQSGWRWGYGMFAIIVPAAVAPITITLYWAQHRAKKLGVVATNINDATGEVDAPRIVSNQPFLLKFWNFLIDMDALGLLIFAAGWACLLVPLTLVNGAYTTWNSPSIIAMLVCGGVILIGFVPYEAYVAKIPVFPLAFFKNPTILFPAFIGFFDFVSFYLQYTYQYSFIFVTRDWSTVDQNYFAYTQTLALTVFGILTGFVQAYTRRTKWLLTLGLCIRLLGVGLMIKSRGAHGSTGFLVICQVLQGLGGGIAACSSQLLAQGSVRHQDLGTATAFVLLWAAIGNAVGSALAAAIWRDYMPKQLSQNLNGLLNSTEIDTIYSSIVTAVTYRSDEAVYNGIITSYDYTMKILLIVATVVAVIPVGLSLFVKDMYLSDKYVVHSFVHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4C2</accession>
    <name>A0ABQ8V4C2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_37520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="2">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="77" mass="8273" checksum="835E4193EA0DD646" modified="2025-10-08" version="1">MAKDGAFALNNFLQSKNRLSALSWLNSTSGLSHAPQWNCICKIDGEVMGSGTGPQKHVAQDIAANQALKTLIDTNWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Y2</accession>
    <name>A0ABQ8V4Y2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SEN1 N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_632572</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024481">
        <property type="entry name" value="Helicase_Sen1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056474">
        <property type="entry name" value="SEN1_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23576">
        <property type="entry name" value="SEN1_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12726">
        <property type="entry name" value="SEN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="1256"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="1274"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="940"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1765"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1421"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1765"/>
            <end position="1778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1792"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1837"/>
            <end position="1850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4468964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1892" mass="213035" checksum="9589B71F9E6CFC68" modified="2025-10-08" version="1">MAESSRTVSDLAVQKLLQRLHDSPSNSESVQEVELDTIYAYLQRSSVTKLSSLHWFCRHADRITTQAAIFLLRLFAYSSPKVETWKGWLNGCLGGCSECVMGLEKAKIISRDSYFGAFPEHVMSAFWDSFNNWELEHTLAQISDASAWTDIPTPTLYRMICNFQIFQDSRIQTFLEQHPPSRSPSDWPAEPIPPAMLVLMMHENATLRDWSVKQASRCTNIPISQDDAAPLLYDQALEIIMLPFISTAQARSDSISIRLITETVTLWSSFHSVLRLLHPKHLTLFSSKGVDVRHVVTGHLHDHGPEFKTILQCFNLVLKRLGKDLWQGEGPEYPQVVFDAFKDNPSLNALLHEKDFSPERNPWFFNWLSEFLHTIRDQPGYSEVVAKITDFMCEELQHERFSDARPTVIACAARLLKGQKRDGINFAVANVLDIHAESFVTVAFATSHQKAEWQIAREATRGLIHTSLMQDIHDIHDAISRCTIVLALSLRKNEENGSKPHLHDNGHNSMAPLVIREQIWKKIYVHLQPTDIDGLAFLLAVLASAAHLDTVLKNSFGPALAFPGFSALLDSVNRSLEVIRSGFPELASAYEMSITATQVLHHPDVAKDIVKLMLSPVPDLHGGAMGIVTQANDAGSDGRRECFQWLFENFTEESFMGSFELLKVFNDYAPRVPEACSLSKSLVRCFTDIIGVLCSSHRGLLHRSEYLRSDGPARRIPELWTLMCKTITVIFKRTPSWSQYYKTEVMTEWMRDALIFARDILGERAVFESAAEAADAVVTKSSEISKRMLMNLQEILAELSRWLRLTDEELLHQTCTLIHSLLELFREKHDPPQQVVLQKLSKQITDVRNRDSSSLSCRLDPAKLAPLEAILASFDDDVEIVEVSKAMPPPKVPAKHIRKAKAEVDIGLKPTSAVSRSLPASTLKTKSARFSAADQERLDAANSMPKFRKPAATSVPNVAPHSTKPSAASGSSREKGESGSSSSSDESEEEEEESQRSLMAGLVKLQQSPKVRKQVQRRQVKMLDLPHLKQNAQEARLLKRDEARQKALRFKPDISGLHRTLLSWDYQHDGESPPRTRLQLRSVPDTFSDFNHYRAVFEPLLLMECWAQLLQSKDESSESYNCRITSRLYNGQWSDLEVLFLSDLRKEWFLTENDVVLLRHPEGKSTVLAKAISFRRPGKDPAEAGLRCYFPPDARDPGIQIQSLWQISKVFSLSTLHREYAALVAAEYYDFADHILRPYLALPVGVDTKEINQMMNKFKVNEPQAKAIVSALKSDGFVLIQGPPGTGKTSTICALISASLETISQGPSKNHEKRKVLLCAPSNAAIDEIVYRLKDRYHSLKVVRTGAAQSISPNVKHVSLDYLVEEKLGMQGQKESSETANDMISARQEFQTVKNLRQVKIQELQKLRDSGARFDSLEVEVKQLTIKTTALRQRLDNLRDKHTSESRKMDTARRRARDEVLREADVICSTLSGTGHENLEQYEYDMVIIDEAAQAIELSSLIPLKYKCNRCVMVGDPQQLPPTVISMQASKYQYNQSLFVRLQKQRPEAVHLLSIQYRMHPDISRLPSKIFYEDRLQDGPNMDTKTAQPWHTHSKFGTYRFFNVKGGLEESSGRSTKNRAEAQVAVALFNRLRKDFPSVDFTFRVGIVSMYSAQIRELKIAFEQRFGREILTQVDFRTVDGFQGQEKDVIILSCVRAGPGVVSIGHVKDIRRMNVAITRAKSSLFILGNAATLERSNETWREIVADSKARNIFAEVDVSYFTAPSTMATGTPLTGTSPRKSKQTKPTLPVPQHHDLSTPKELKAAALTKPPKSSTSEPLPVNDAAPTPLDKQKGKRKLEEMADPKPDSSHPKSVPPAPSATNTRPLPAPHPPRKRPKQSPALFIPKNKNKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V550</accession>
    <name>A0ABQ8V550_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_775953</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="120"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4472753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="358" mass="41755" checksum="ABE0CB351B47083D" modified="2025-10-08" version="1">MYTFPEIDLLWDLLRIYFTEVAPYFPLLHRPTFEKAVINGRHLLDPSFGALLLAVCAVAARDSQDLRILKQDTKITAGWQWFSQIRLVRPNFVEPTSVHELQLYCVSYLYLRQTNMFDSAWSLVGLGLRLSLDRGIHRLKTSKSRDAESELWIRIFWILRNADVLQGLSLGRPAAIDSEHFDLDRPVECDDGYWEKTEHNESFTQPPGKTSGLSFFTHYNKLVDIAASVQRSVYCVNEVPEYKDDSLTPVERNRKKAMQHDSALNHWLMSLPEHLRWDPNQPDKIRLNHSAILYTTFYWIQLQLHKNFLFRQASDNQQGFPSFAICANAARSTVRISQVLHQRSKNRFEVLVRVRFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V561</accession>
    <name>A0ABQ8V561_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_897397</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045596103" evidence="4">
        <location>
            <begin position="20"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4474797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="408" mass="43849" checksum="0D0FF5439E7C924D" modified="2025-10-08" version="1">MIMIYPFVILCSLLFGVTASPLAPTETPGLSVPIRKFVNVTSGHNLVNTGRSRAQSFRDRAASKRTSSTKRQEVPVVNEIITYIAEITVGADNQTFHLLVDTGSSNTWIGANSSYAYVPSSSSVWTDDIVIVDYGSGYFFGYEYYDTVALSNDLVIKNQSIGVADFQQGFTSMDGILGIGPVALTDGTILGDLAPVTTVPTVSDNLFTEGIISAEVVGIAFVPTTGAADEPEGELIFGDVEGSSKYTGQITYTQKETDYWGITQSISYSGIEIMASAVGVVDTGTTLNYMPTDAFNAYINSTGGIFDEATGLYEITEEQYDALDDLVFTIGGTDFPLTSNAQIWPRTLNANIGGEEGKLYLAAVATDPVEDLNFINGYVFLERYFSVFDNTNSRVGFAATAYTNATTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V665</accession>
    <name>A0ABQ8V665_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="10">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_888016</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="352"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4474559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="609" mass="69238" checksum="249637AF07FA5CAD" modified="2025-10-08" version="1">MLSSLLARNQYSSRIPSFREAFSLLAGRPLRWVPQLLGFLVVIWYFGPIIRGGPPDDYVYELPLPIQHPHLPPLYKPPTASANDWKLRSHQVREAFVHSYKGYRDHAFPADELGPMSGKIHNNFNGWGVTIYDALDTMWIMGLTEYFEEAVKVIGEASYTTKPKQYVPFFETIIRHLGGLLSAYALSKDPILLQQADRMGEMLLPAFNSESGLPAYAISTRTNATRGGWTGNTLWAEALSNQLEYKYLAHITGKPEYFEKAERCMQLMYEANVTDGIFPTQWNTKTGAPSNNKFSVGAFADSAHEYLLKQWLMTSRSETKIKDLYLNASKSIIEHLLYITPNREMLYVTDADMLKPSPPKPNASPESPRTTTQGATSTPSSVPSGTFEHLSCFLPGLLALGVQTLDLPESEKEIHLWAAEGLAYSCWLTYADMKTGLGPDVMSMKMYPKNEDGLWLPRVEKWKQQGRSGRPPGLREPGAASEKAGRDYTIYKRSYLLRPEALESFYIMWRTTGNPVWRERGWTIFQAIEKYAKTEIGYASIVDVDKSSTKAPVKDEMPSYFLAETLKYLYLLFTDEEIIPLDRWVFNTEAHPIPIFEWTETEKKLFNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6H9</accession>
    <name>A0ABQ8V6H9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall beta-glucan synthesis</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_776320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045042423" description="Cell wall beta-glucan synthesis" evidence="2">
        <location>
            <begin position="17"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="27143" checksum="F6E9A27F0B2D780A" modified="2025-10-08" version="1">MLTFIISCLFFSVVRALPTFLSRDVFDPPITSPSASTIWQVGQTVTVTWDTTNLPPTSQLTDPNGTIVLGYMASSTDSEHLMIDSPLAQDFALSDGNVSFIVPSVVTRSDYIIALFGDSGNISPTFTIQGTESTSSAPTTSTSVSTLSTSSSISVPTSSSPSTPQTTVVTEAEASSSASTFASESFATNTVTSVITVSSGIASSTTAESGSASTLSASSLSISSTSGSSASPSATEAAASSNGAWQPGVSQSQVYAFVVAGLLAACLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6R8</accession>
    <name>A0ABQ8V6R8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_737086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="27075" checksum="F2C44017A3137982" modified="2025-10-08" version="1" fragment="single">NAIFSYLDHNDIDNLGLTCRWLEHEKQQFRSKANKIDLVLNRFLTVGEISGFQDIQVLTGMVVSGSVALQFFSREVYRTDLDTYCVLGKCLDVAKYYQSIRYEYRPSKDQLDHFEDDLSRIVDWRWYTENRGPYLQDNVLQVWNFDRNGSKIQLIATARSPLEAILKFHSTCVMNVITHRRAYCLFARTTFKERCTVVIDRGDRYNATGVEKYRARGFEVVDVPDVDRILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7A3</accession>
    <name>A0ABQ8V7A3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_778318</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4469004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF20">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="7">
        <location>
            <begin position="51"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4469004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="39991" checksum="24B9584383FA94DB" modified="2025-10-08" version="1">MALPFKEALSRLENRRVKATRPLIPPQILQEDLPLTLLAAQTVIEGRMQTENILKGSDDRLMVVVGPCSVNNVDAAREYAHLLKAYADEAKEDLFIVMRVYFEKPRTTVGWKGLINDPDLNGTFQINKGLRIARTLLLDIAKLGLPAGCEFLDTISPQYTADLVSWGAIGARTTESQVHRELTSALSMPTGFKNSTDGSVGIAIDACRAAQSGHVFLSVGKEGLSSIVETEGNPDVHVILRGGASGPNYAAHFVRECGLKLGKAGLSQKIMIDCSHGNSSKQHKNQAIVADDIARQMAEEDTSPMIMGVMIESNLVEGRQDIPLSGPSGLRYGQSVTDACMDWDMTVEVLNRLREGVKARRARIAKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7K3</accession>
    <name>A0ABQ8V7K3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Autophagy-related protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_844386</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Preautophagosomal structure membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ATG17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007240">
        <property type="entry name" value="Atg17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="8">
        <location>
            <begin position="22"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4478587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="482" mass="54930" checksum="5DAB980953EC1EDA" modified="2025-10-08" version="1">MSVAPASDPHIVSLVLQSKKALQEGEQICSNANELSATSTQTSIDVLILDAKVKWITDNVLEQLKLAAFVAKNIEEKRTKLNKQVQDWDNLRTEQTDALDKILNELGSQRVPPDFHQTSTASSIFGSQDSEDEQQNDKQSNGLSTLSRSPSDTIQVPRPKPQADLKNWKTLRDFVDDQAIEDIFECMEEEHTIVEDILSRTDEYSEKLTTAIHSIREYLPEMIPPPSIEQLITSQDSAQIGMAGHLESLAAHYDQMCNALREREAGDVFGEDDLQDMNRDTEELPSILSELEENLRSVTATYDQLCQIRDTNQEHIKRLSNVLDELDELGDIMTEMLQTQETVESECEQRFTQMQRHVLTVEDLQQQFISYQTAFRKLILEIARRRVYKEAAENIVRGMMDQLTAMTEEERRVREHFNQEQGAHLPEDLCLCISNYPTKWDISPWAGEVLESLPDIPTDMVTEARNHVRTEPPSVVNGTESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Q8</accession>
    <name>A0ABQ8V8Q8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">RING-type E3 ubiquitin transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_499863</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF70">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="508"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="468"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4479893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="562" mass="62501" checksum="18EED0B48B5D7012" modified="2025-10-08" version="1">MFPCSICKKHFDTFRALKEHARTSRSHHPCGYCERIFRNLYTLGRHIDAKHSTKEGETKSYTCRPCNRSFASQSSLVEHYRGSEAHPTCPKCGKGFENRRSFNEHQQLRGPCNIQIAQVFCSSCDMTIQKDDIFQHYLESPSHPTCHQCRVGFVDDRDFEQHCLRLHDLTRCKQCGRQYENVAQLQQHYLTSIRHPTCSACEIGFETEKRQQAHIQTIHFHSDPVNGETDVQLSHVSRVPSPVYVSQPSSPYRSVISRSVPIIENEDTLSTWTSCVFPDDEPPSVKPGFSSSGPSDITTPKAKSDDFRPYWTLNPPSPPAGALSSPEVQSPLELDALPTISPTPSTPISLSTIAPIRQVPWSQWGGSVGKAVSRPSLPRIATRLHKTPIESVKSSISTSLARDLVLLGFDKGNNSLLNTQAPDLSSPALMNDLSWKFNASMDLRPNGAHPKTENDQWYPVQPTYQKAVTRPSSNSSSTSTLNSGPYSRSSTIESPLSASTVAAVSLHCRLCMRDPCIDPTATMCGHIFCGNCITESVIVSPRCPVCEHALLLYCLFRLDLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Q9</accession>
    <name>A0ABQ8V8Q9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_850810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4471215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9767" checksum="3281BA2719F23634" modified="2025-10-08" version="1">MRKIIDHVFSMQPALFFFTLSTFGFGKGVLSIRPTLHASLSNSRHRTASSVLKCPATRTPSSKRALLTKYRDRTAAFALQVLNRVGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9I2</accession>
    <name>A0ABQ8V9I2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_464165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="162"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="517" mass="59326" checksum="207678B164A1091C" modified="2025-10-08" version="1">MIEDCPASVGRIQSDNLPATPHPVSPHSASTLASAPTSLLCEDESRLHVNIWSEDKKKTVEIATVQEKSWESSRVHGVEDKSSKNDEWKKLLIVMVCQLKKTPRTTKNAGSIPTLYIDGIEYLQDPELFSHTFALDTQDLIDAIYSFVGTDGCSRKVVIQSILHHAEDAVGLYAVVAEVECLCMEADCTWNGERKIMKISFMGTDRQSEQGLIGEARSKAESTGELWALNHLPNAIHSLSLLPNKKKVFHRRLKTYLKDKYEERVMHVTVFEKLHPLSELEDPKNFAQVFYDILQIHQWLYECAGILHRDLSSGNIMFRRKEGRIYGVLNDFDLSSRIEDLNKNPTFNVVNHTGTRPFMSYDLLNSSWKRGHLYRHDLESLFYIILCLACRYRKPGVPADEPRAFSKWYSGSDKEICGEKCVFLLSPYTNLPIQPYFAGFTSWLWLLFEDICVGYKRRPVYRLSTSKKYLKHSDDGEGLGFDWTTLNKCVTYARMRLIMSSFEGQKLETRWIGNQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAR1</accession>
    <name>A0ABQ8VAR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_897143</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MoaC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4478007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21117">
        <property type="entry name" value="Twitch_MoaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040064">
        <property type="entry name" value="MoaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047594">
        <property type="entry name" value="MoaC_bact/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01383">
        <property type="entry name" value="cyclic_pyranopterin_phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01386">
        <property type="entry name" value="main_SPASM_domain-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01067">
        <property type="entry name" value="SPASM/twitch_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="26"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4478007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="526" mass="58708" checksum="62E13F3A4F789E21" modified="2025-10-08" version="1">MTVSAYRNQLLRLWTRTFSISALVDSYNRRHDYLRISLTERCNLRCFYCMPEEGVQLSPNEKVLTDEEILRLAKLFVRSGVTKIRLTGGEPTVRKGVVGIVAGLNELRPYGLRSIALTSNGLALHRRLPELVENGLTHLNLSLDTLDPFKFEFMTKRSGLEAVLKTLKVALESPHLQKVKLNVVVVKGLNDNEVLDFVEMTKDRPISVRFIEFMPFTGNKWDKFKMVPSSDLLQVISEKHLGLERMADETNVTARSWKIPGYQGEFGFISSMSDHFCSACNRLRITADGQIKVCLFDAKEVSLRDEIRKGASDSEILRLIGRAVHGKEEKHLQMEDIDVVSNRPMILIGRASMVDVSEKSVTKRSATAKGRIIITERAYDLINKSYSSESQSSMGKNPSSMDEAQKKVLRKGDTLTVAQLAAIMGSKKTSDLIPLCHPLPLTDVKVKLTCEAFEETQGTWKYSVVCQATVACEGKTGVEMEALTAVSVGLLTIWDMLKAVAGKEMVIGEIMVSEKSGGRSGEFHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAY2</accession>
    <name>A0ABQ8VAY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_983124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="851"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="912" mass="100907" checksum="D9E91898542E00B3" modified="2025-10-08" version="1">MTGANYMGGKRNAAKARVRDSASRAQKRYFGAQRLNLAANRGSGMTEKSGVNLILDLAQTNGSTKSIPDIKLAHARQNSSNTTNQIVGYIPDPIRISPCTPKSQLRLSKISMDSNHTSSARIKPSRILQALDTCERRSHPTYPDVKAFIHFFEKAFALRAAMDEVLSLSDLAGLSRRPGRNLKRHHSSSSPCPREESSKQHKAALQFLTSSDSSTFTSTEVSDLGPSRRESSSDFEEAVVESQFAFNIPDDGVLGKDDKQGYSSDNNISATWTVYPNRKTDSPEMTRYIGPADRSSHRPLSRLSEPKHLNVTSSSPSYHVNSDNPMEYPHTSNSFSQTTPESNIFDYEDPWMAIGVMLGVEKTPLKPLKKRDFRKILAEIPTPVATPTSNVNIFATNDLVPDIIAGSSSPSRLSDSKVRVSPSTHANTDAARNQFRIFSPSVQTQPIFPNTFRSLVSYSSDEANFDPLSSPTDVKRLQPVLDFSIDPGRGIANQAQSDILTNIRPRSGSSEFSSPNYAREGKAGSYLAPEQELPLFPNLCNDLDDVNTNDHRASNRAADLSSSPLFGHSLYSSSSHTRGQVLPRHRRQRHELTHMHNLHHIPDGLSDFQGVAASQGGDPSSPSLTPIQFALSPRRSNFDSKYHVNFPFSAIAQAGDEYLHTPEQRTRIGTYKNRTPHDDTDALTIRLVTTTKQSTADSPSIVNPDVSSPNDLQLHASQSDQLRDNRRFAPASIPRLNPRTKLSTELDTSLHRAPAGYRSPAVCPTNATENLPRNPQTRRMPLLSRFNASHAIPSSQSTLPTLFLKSPARPSARNYSHENTSKETDFQDTRQSTREDNQKTEIVFPTPARSIVRDSASKPEEEEVRERGLVESNVSKQPIPSAEVRSEKHSSREALRFSLFVDDEIVSDSESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBB8</accession>
    <name>A0ABQ8VBB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_921426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4485116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="44257" checksum="619EF5E13E72BB4A" modified="2025-10-08" version="1">MKLAPRSFGRQISAFQNFHCNAYASRIRLANPVLVQRRGIRTKPETLRLKTHKDGPTAGEKVLMQRMLEQRQLNISKVARERGWFFPSKYLQLPFGWSYEWPAWVAGWELVPIVTRSHNELVLEHYFAMSGKSTPIIFHLDPHAPDFIFRYDGMDTQDIQRKGTSWMDQGIPGAYYYFRMGDDEVFKFPSEFDTYSPEEFILASGSTPGLEHMMKETSAVSVSSDDHSSHRDTFAEECDLELIQFEQRLSDLENETKRKDRAETIMSLAFGDSMEEPLYPITDEKILALRKKYESYKAYGVYSVYSLVPDDEALKAEERRKRHLQYYHNVENLENRVEELKRELHEITDDEGEFEVVKQQSRGRRQKRDNRPRKLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBF8</accession>
    <name>A0ABQ8VBF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_493851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047088145" description="Protein kinase domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="38831" checksum="6D2D0E4CFE4B8DB1" modified="2025-10-08" version="1">MHFCSTFLNLIFWASLLLAAGAIPYDRSKRGVYQSDPDLGTSALRHSVVPRLQLRSSETHSLERRKEAGAAAQEFANEWFGQLHHEDWIDYSFNSKCVGYDKNEETFMRNNLTTEVADRKLLASFGSYNKGIFTLPNLKDSVVKLVRLTGLCHETASCEIESLKAFGQQVTSGFATLPEGNVGVIIMKKVEGIYFSESSKWMFTLDEAQKLNALDALKQEVQEMIYNLLREGKPLFSDFQDGNILIDEEEKAHLVDFGFPGVWPVKMVPERNVFNKWFERRWYFLWESSYQQLGYPVPVFYQEPISKKKNKWSTSILTKLGLGRSKRKGKRGSFAIDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBJ1</accession>
    <name>A0ABQ8VBJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_896429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4485142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="35915" checksum="996213F54FD43E95" modified="2025-10-08" version="1">MTVRTNTAQRLSQQLRLLSSQPSSEMTSQYSPRLIGAPNTLEHRVFVEQNGSVVSSFHDIPLFADQNNGIFNMIVEVPRWTNAKMEISKEEPFNPIKQDVKKNRLRFVRNCFPHHGYIWNYGAFPQTWEDPSQQHAETKAKGDNDPLDVCEIGEQVGYVGQVKQVKVLGIMALLDEGETDWKVIVVDVQDPLASKLNDIEDVERHLPGLIRATNEWFRIYKIPDGKPENTFAFSGEAKNKKYATEIIHECHEAWRRLITGESNPHGISIDNITISNSPAFVRRDDSSYLSIPPASSKPPAPIEPSVSKWFYISSAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC80</accession>
    <name>A0ABQ8VC80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-hydroxyacyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_414732</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4486954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="31470" checksum="736126C8B53E4CEA" modified="2025-10-08" version="1">MRISNRTFVISGGSSGLGLATVQELLRCNAYVAVLDLSPISAELVSDETCSSDDTSQNPRVLYIETDVTQEDRVESAVDRVVEWTKSTGAHLGGVINGAGIALAELTINRRGEPHSTRTWDRVLGINLTGTFYLTRLVAKHLVTVPREYELEEIARQREEEKEGMTMKVSDGERGVIVMIASTVAAGQIAYAASKGAIRSMTLPMARDMSRYGVRVVTIAPGPFKTPMTGQFSQSMTDRLEKEAVLFPKRYGMPEEFAATVRWILECPYVNGETFKLTGGTRVPAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCL7</accession>
    <name>A0ABQ8VCL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_471247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047323587" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13315" checksum="7877A94DF418B2D1" modified="2025-10-08" version="1">MVQLSVPYVLLITVPTLAVSIYKSNKIHLVLAHCVSVRLTAFSILQHLCAARSCYVDPFRYERFGHTTVKKKSCCDVQISAREWQRSSVQSRGSVLIFTLFRSGNRAHDAIDPKEGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD63</accession>
    <name>A0ABQ8VD63_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_770657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="228" mass="26012" checksum="C2954607E4B0C83E" modified="2025-10-08" version="1" fragment="single">NVAQLVYNLLQIMFLDPCRRFTFGMTMQGRELRLWFACCGFVLTTKLCDFLKDHARLVHLFVSFAFSSRTDFGWDPTITCTDPASNPSDPRKRRVYSIEVRNDQGEVRWFETIRILADYAADSTVSSATRVWLVRDKQGVQYVLKDVRLDMDRLPEHEICAQILADAFKHCGAADQATLKRHFLTSYVCGKVFVNDGVDTTDGIMHQELPTISSDSMFTLGKINNPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDP0</accession>
    <name>A0ABQ8VDP0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4483123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20297" checksum="0FB665F419958CCD" modified="2025-10-08" version="1">MVTAVYIPNTRRLRSGCTAPETLKKLPGTVTSHTKHSSSTSSSCSSSSSASTSETPVSTSTAMRTRMNDDQRRAKLERDLDIVPGTVHPRTVTCRGCEHTIRLDTKIKYGDSNWRTHKKKCVKLREEDRTISDILLSLNVEVRLQKISGSSQANPSEDLAELEYCAVQALRDVQKRMDHSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDP1</accession>
    <name>A0ABQ8VDP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_393399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045161569" evidence="6">
        <location>
            <begin position="22"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="337" mass="37323" checksum="FD6541E632426DF6" modified="2025-10-08" version="1">MFCKQVSLVLAMFYGAALVVASSEGSNLNSRNISDIETRDSTRPIAGFIMKVWPAVIGAALYGISGLLHWIHFFRVGQRYMLTLTIGMSLMTIGLALRIAVSHSPYSLTLYIVEDLLVLLSPCAFLATDYLLLSRLANSLGCDIADDCLLIPSRRITKIFVWSDVITFWVQASGGGMSTSESLSSAGTTVAMVGLVLQLVSFALFTCLLISFGFRVRTKYPDAWDVQSSVLSVAGPFKTSTTSNWKILYYTMCLTCTGILTRSAFRIAEFAGGYNGYLAIHEGYFFLLDTLPLWIAMTLYCFIWPSRFINQDEKNIEVRGSPFSLVESNRNNDNYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEA4</accession>
    <name>A0ABQ8VEA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_921327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="67725" checksum="28E32C19F191BE03" modified="2025-10-08" version="1">MTTSFESSSWNSMRSPFASTIGTNHVPSMDEMLRLKALLAVPRTELNRLELEIARTQLVLDGLLRQKEKINNYIGAHQALMSPIRQIPSETLADIFVWCLPADRNAVRSLKEAPLLLTTICRNWRQVALDTPRLWNSLHIFLPPYLSDIAVSKRAIGVKTWLQRSGSLPLSISFHVKPLSGAPPTTTTTTMDFSDRLKLLIRTLVPFGHRFGNLFLSLPSENLRAFDDLLMCQFSILQSFRVRDANVFCGFFFHPPDPWNDGSHSARVPFAPLLTRMPALRRLQVAEISVGDGGHLTLPINWGLLTDLNLQGGDLMTDQCYGVRVTEAFDILRKTSNLQYLQIRITLIPDHPFEGTSLGMIHLPHLGSIRIKFISFQLDDHTIPAQVSSVFEYISPPSLKLLSVACYHPLPMGSALSGIPFHTLETLEIAMRMTSETLTGWLSCVPELTSFKFKDLGCPAGAESLFAFTNTFCDSHLLALTPSHDNPSPLCPKLTTFRMINHLPAETRISSSALLGFVLGRAPTLKTFDLFFDRDQLFAENDLIELRKLKRNGLQMRLHYAKYPLHAEEDLPSDGLHPRPNSQPPIMAHRISDMDGAFGTNRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEJ8</accession>
    <name>A0ABQ8VEJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_833770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29383" checksum="5981B352004CD2E1" modified="2025-10-08" version="1">MSRPIVTFYDRPGLFMPTVEQGSLIQELRAVAAASFCMDTSQLPNYQCLAIDDPFALSDKLIAVGRAPSTGCIIGFISSVLVQIPDFSEGEVLHVGLACLSPSSKLETVSGLAKHLMASIVYGYLLKNPSTSKVWVTNRSSNLSTLGRFAQTVDEVFPSPSHPISPPTSLHVTIANAIIGSSSRSLNVTPGKLDPRTFIVRKFLFHAGKDEDQRNDRYHYSNPKMWEFYRGYLDENGSKEDESGILQVGHISPRMLYVLRGIMLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEK3</accession>
    <name>A0ABQ8VEK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047205953" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="15523" checksum="103D1C0BA54F2B3B" modified="2025-10-08" version="1">MSCTVLALLVLTCTSVAQKALFAYPQDGDTLVAGSNISIRIDRPTPSGPVVEAGIGLGMSPCNESCPSPETSFEYLFYAGAFNPQRPAQVSLGEDFNAFQNFTVTVPSIDGPAILGFLHSSFGEGADAFYPYFESVNITVNVVPSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VES6</accession>
    <name>A0ABQ8VES6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_767124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127065" evidence="2">
        <location>
            <begin position="28"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="286" mass="30091" checksum="6A6D806CBBCAD859" modified="2025-10-08" version="1">MLTRWSHLCSISTWSFLYFPSIIPCLAQQGGSLQNTSIANTSPQIDYTPFVCNVTGSASFSPNCLGGWQVLSSGGGTIVSTGGAGPLGANIIPQMFLQFRASALFLSTSPSSNASFEIAVSAGNTSVSVSANSSIGVAAILNLPENATTTLSLTFIPGQLPSHLDIGTIAITVADNSSISSVLPTPTLPPTISLPSFISSTSSSLPSATSTPSSQSSDSSHKQLVKDAVGLTVGLGLGLTLVASLGYYTWKRRRRRQGDAEWRHSGDQRTISLRRRTDNQDTTRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGG7</accession>
    <name>A0ABQ8VGG7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_326950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325725" description="Secreted protein" evidence="1">
        <location>
            <begin position="39"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10456" checksum="097FD7B4DA5DB50F" modified="2025-10-08" version="1">MAQMAHGFWGTVRSNAHGGRWRHMHALFCLLRFDLLSSFLIESIDRTRRLTVGENWGKWQSRRKSIERITSRTVLSYAFKAMKSQTTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH81</accession>
    <name>A0ABQ8VH81_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="7 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_829652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="7 8"/>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.320">
        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006765">
        <property type="entry name" value="PRK09287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="7 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="179"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4494295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="489" mass="53369" checksum="45A83D276E2E0FB7" modified="2025-10-08" version="1">MATGDIGLIGLAVMGQNLILNMNDKGFTVVAYNRTTEKVDRFLANEAKGTKIQGAHSIQELCSKLKTPRKIILLVKAGQAVDDFIAQLIPHLEKGDIVIDGGNSHYPDSIRRTKELEAKGFLFVGSGVSGGEEGARHGPSLMPGGSPAAWPHIKEIFQKTAAQAYGEPCCDWVGETGAGHYVKMVHNGIEYGDMQLIAEAYDILKRGLGLSEDEIADIFLKWNKGVLDSFLIEITADILKFKDDDGEPVVAKILDKAGQKGTGKWTAIAALDAGSPVTLIGEAVFARTLSALKDERTRASKVIAGPQKEPFRGDKQMFIDDLEQALYASKIISYTQGFMLMRQTASDLGWNLNYAGIASMWRGGCIIKSVFLSDITKAYNNNLKLESLLFDDFFNKAVHNAQPGWRRVIAQAVLWGIPTPAFSTALAFFDGYRSDIVPANLLQAQRDYFGAHTFRVLPGKENAKFKKGEDIHVNWTGRGGSVSASTYNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI03</accession>
    <name>A0ABQ8VI03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_828477</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="747"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="850"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="893"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="938"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="994"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="768"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="895"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1043"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1163" mass="129450" checksum="DA17CC30EA20E660" modified="2025-10-08" version="1">MPQATRKDPTMQRAQDKESKRARGALSCAECRRLKLKCDKTVPCSSCKRRGCSSICPNGVLITGQGTRFVLADTEKLHAKIEQMSDRIRSLEDALIILHSTTGVQEPHPLLDRDLLKIKSSLELHAAIQSDSKVKEEEMEDSQYLDAFGTLAIREDGASTFYGRSAGSESLLIGETVSTPLDGRDPHSTTQVNGQSLNGVQTIREWQQQAAQARGLPTVLSNLSHSFPLPASQPIPDLDYLVDTFLPPWQEASRLCELYLEQAPWFFGAVTQRQLVEEILPMWYTEAPRPAVAPSLNQEGVSVGDRGVDTPPLARSGLGVGTMSSSSPLGTNPNPPADFHQSSSTSAVHNGRTGGAHDLALLFMVFCFGALTDVNLPAAPDNMQSERYYDLTKVGLNLEGLLDRPPSVATVQALSLMGIYEGMRSGENSIESTWALMGMATKLAQSIGLHRDCARWKLPPAEVQKRRALFWELFITDCWQSLATGRLATFSLPFVDCELPYDPDGTISDDGTVQPSFPFWKARFGAECVSAVVQGTLTSRAPKYSIILDLDRKIRDMELPKYAQGPIPEGAGLKETMSCCMPTNYRELTLLYIHRCFFTHAIQSNPTDPIKSQYAPSFLAGYRSACDLLNAVRKQFTMFPAQIARFWVLWTHAFSSTVMISSVVTHGSRSKVAPAALFELKSACELFEQAARHGGRAVKFLPIVQRLLGKAQKVYYDTCNGIPPAIPNDIFRPSNTGSDEISVFSGKTHTVATKAPRTPTARSPGSNGSARSSQSPNGSPSQSHLTTNPSFAEVHPTLVQELNGFEGHISAQLQNAYNNPNFNELLMGPYASQEISGQHQYEAEHLARQQYEQQRRELEQQKSEEQERAERQYMEQRLIHQREEEQLRVAEEEAQAYAQTQRQQQQLHYSYHHSPTSESSISIANGLPITAHVQDQLMQDQRRTLSHSQSHPNLHRVAGYNGHSEYNQASQVPLPNHYNYASQTSSEQQHIHIVTHQQNQHRPPPNRPHLHSHHQHPSTQPDPSHPPQHEMYAIPTEYMPVHSSPISSDVSISPTSSAPPRHYPSPEAVFEAHNQRSHPHDGVAAGGNYWPNGQHQTVPEGVAYNHHHAPRRGPEQPQQYNHTHQQYTPEAAMQGMAAEDPRLQETWRSYMYKVGSPRLMLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI54</accession>
    <name>A0ABQ8VI54_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_833930</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="131"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="312"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4491743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="44557" checksum="C5DA1A03B1B91FD2" modified="2025-10-08" version="1">MSNDEEVVVNKNKSHRKDKPWDTDDIDQWKIDPFMPADNKAGAFAEESSFATLFPKYREKYLREVWSAVTRALETHGVACTLDLVHGSMSVRTTRKTHDPYIILKARDLIKLLSRGVAVTQAVKILNDDISCDIIKIGNLVRNKERFVKRRQRIIGPDGSTLKAIELLTQCYVLVQGSTVSVMGPHKSLKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPKLATESWDRFLPQFRKNHLKTSDKTAKKNERLEAKNAARTAAGLPIESSADVAAKKKVYTPFPPAQLPRKVDLQLESGEYFLKKHEKIAKESAQRRQKQTESMEKRRAERAEAFVAPAEDAAPTVEEKRKRKRKDMGSEMTRDQQEADGTKKSKKKKHKVEEEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIK4</accession>
    <name>A0ABQ8VIK4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_902807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046145183" evidence="1">
        <location>
            <begin position="19"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="202" mass="22003" checksum="643A1DED97767765" modified="2025-10-08" version="1">MRLNVAPLVLALAAAVYAVPITNENPAVAPPDATVVPRGASLSQIPPVHMALETIADSRRNPDLVSFIHEVRAIHRVPTTSEVPANPDGPIHYQFFVHPPSSETHDPSVKRKAQDAVHSILTPFGGTREIMEEEGHLMTSLEMFGFQVNSPVVIGDPAEGVTCPCDVWVRVKEVEGQRPITALITSYATKKEAAYLTVFKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ02</accession>
    <name>A0ABQ8VJ02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine nucleotide binding protein, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_828152</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF360">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4495478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="490" mass="55372" checksum="38507C8148FECBE4" modified="2025-10-08" version="1">MPSRVYGPTDPDSWDPLTNAISPPSDESAQEREIRIKHELEAKQKSDAIDEDLNRQRAAEKKGPKPVRVLLLGQSESGKSTFLKFFKLMHDPKAFSAERASWRAVIQLNVVRSIHVILDAMTHPSQPRHDPRKQMTSSASSSPLSGEIPLPEDTSDVEPELIQIRYRLSSLLQVEDSLTRQLTPKDYSEVGTTQLAPMNHIKHVATELAINSSVPWKQRFDRLVGKGDTERMIIDWDDPNDPGKILHACGEDMIRLWQHPNVQQMLEKQNLRLEEMAGFFLDSLSEITAERYLPSDEHILRARLKTLGVSEHQVKVSAGSDIGSDWRIFDVGGHRSLRAAWAPFFENNLDAIIFLAPISAFDQVLAEAPKVNRLEDSVSLWASIVANKILQRTDLILFLNKCDLMAAKLASGIKLKDYVVSYGNRPNDFDSTTNYLRKKFAGILKENSPLPRTFYCHYTSVTDTLSTQKVIASIKDMLMRDSLRHSTLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJS9</accession>
    <name>A0ABQ8VJS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_763829</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20537">
        <property type="entry name" value="CYCLIN_CCNO-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20559">
        <property type="entry name" value="CYCLIN_ScCLN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="111"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="206"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="210"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="430" mass="49305" checksum="861D92E8106D82B4" modified="2025-10-08" version="1">MKDLSSTSSSSRHARNSLIYPKKRPSPHGVSKSHKSPLFSQDVMRKSPRSVKAALIQQRQQLRRDGVILEDEYREDIRCYMHEMENYTMSSTQSMDQQPEIRWHMRPCLVDFLVEIHFSFRLRPETLYLTLNIVDRYVSRRIVFIKHYQLVGCAALWIAAKFEDAKERVPTVQDLVQMCHDAYEESAFLQMEGHVLSTIQWTLGHPTAEAWLRLMCCGPCMEEPKVQHVARFLMEITLFYREFVKYAPSSIALAALTLARFLCGKPARVWEETDECLEIVDLLDTRLAKHVNDLSETLVKKYSYAFYSKAATFVVQYYLQGGTFNRIATAAFPVTPTRSVPISAVSTPMSCSTSVSDGSDDFPLTPITPVLHPPSSDYDDKENRPTTFEPVYNKHRIDSPPEQFLPHDFVTFSRPALHSLNVSSSPRAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJV1</accession>
    <name>A0ABQ8VJV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="204" mass="21727" checksum="B6C4285F0EC04287" modified="2025-10-08" version="1">MSSFDSDPNNFNNTSYESQNRRREFDNQPDSMRSGGMNTGGGGYDQQASRFDNYNSNSNSMGGGGFGQQTPGRDQFSASGYNDDSFGPQSQTGRGGNPGRSEFNNERSYGGDSTGTQGYGAGNDFENNRSTGYGTGNTGSAYGTGNDFSGDRNDESYGSGNNNNNKPSFGDKMKGTAEIAAGKMTKNPGMVERGQDRKTEGNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK56</accession>
    <name>A0ABQ8VK56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_946508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="61"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="485" mass="54877" checksum="2C2471FCFEEBDFAB" modified="2025-10-08" version="1">MSQFLLPSRIEGPIWLSPVEKAVLHKQVAMINQEIASLDSQKDIQLALLASVKNILSPVRRVPNEVLAHIFDDVLYHPENSKKYYAQRNIGKTLSTLSRVCVVWRHVAHTTPKLWSTLCLSIPKHMCALVGDLEWVEEWLMRSKGLPLDVYLILPQNIKHWPGCESWFNKTCDSLVDRLHKFLEKIINEPAHHRDCVSSLILIGHSTFFSPLLKLPASSLPGLKRVFLQVTKDFSASLTQVKAFLGAPKLREVEIIEPYEESQLKTILLPAEQLINLKLMPGPGISFLQCFIVPLLEDLDLDYGDIEFQDFCEIITKFQRQSGYIPNLRSLTVKLGSMDNTVLIPVLDFFPRINSLQLVGINFDVNFLFEAMTYNPSTEQNSLPVPNISTLKLVFKMNNWDNSYPSKLLSMILSRTLPDRPSKLQVDTGAATRGKKTRHEVGVGVHRLQRVSVCGSELEKATEDVAHIAEIPSTTIYSECWDCIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKB3</accession>
    <name>A0ABQ8VKB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_825595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="641" mass="69053" checksum="6FF60A4742A940F1" modified="2025-10-08" version="1">MLDSTARNVDDDGWQVVPADWPRIHFEAISWAHKLPGSRGAPCKAICRPPTKSHYLANQADGNSADLEQELNAELVGVSIALDVLTAYEATSGFHYNLCSDLRGGEFTSATVADISCQIDEKDVAACKENWNEIIQNLTGDFAEDRDTSSSSGSDTGSFSSSLMFDSSDCVYPNYVSMPSTPKPRAPSCGAARSRPSVSPHSKLNASASSFTPSGSSVPSLTFSNNASPLTTRSSPSPTLHDFVFPSLDSTKASSYPKLKIEKDDQGFYTDMEVEMELVTPKSHMHPSTLLPAFLQDDHIRRKGLSSKTRALVDRLRSRQFITTHEDSGYNLSPSPVDPGLHDSQGTSSDVDDSASSSFSESRSIAGVPSLTSTNLSSDTDGWIGLEEFHRSTPPKSRKRHGPNLSLSTTPMHCRTGSGPAALETEPQVRSPSSPSSQEPALSSSSSSSSSSILSPPSPPVITNNDGWIEVSEISRKKSLSCVPAKKPSRASKRKMETEPLTFPTLNATPQTNYRSHTRNASSASSSKSTKAFKSTPAGVLPLLPPVPASNYGYYVPPALPVAPTVSYAPYAVNPMTPYATMMPQYYPHQYAYQQQHTHPQQYAYHHRGHGVAVPSIGSTPASYVIPNVVASPMTIRPGMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKJ3</accession>
    <name>A0ABQ8VKJ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_894843</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF18">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="11"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4496943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="335" mass="36471" checksum="F3D7FCC69B5A74BE" modified="2025-10-08" version="1">MLAILVKDGKGPIDNLYLGEAPTPDPRHGQVMVKIKAFGLNRMDILQRKGNYPVPPGASDILGVEFSGTVSTLGEGVTKFKANDEVFGIAGGGAYAEYITVQETHLFLKPSHLSWTDAASIPEVFLTAYQALVVYGEMKEGENVLVHAAASGVGIAAIQLARVRGAKTVISTASTKEKLDWLVNVPNGATNGVNYKTRNFAEEVKKITNNKGVDVVIDFVGQSHWNKNIESMAMDGRMTMLALLSGAKVSEFELTPLLYKRLRIQGSTLRSRTMAYQADLIRKFTDDVLGSITGEDGQGPIKTYIHKVYSWKNIQDAHRDMEGNQTIGKLVAVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLZ0</accession>
    <name>A0ABQ8VLZ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_917431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="197"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="300" mass="33158" checksum="4315F75F57532500" modified="2025-10-08" version="1">MVAKSAAKSRATTPEYSLRSRSRTSDRSAKSQVFGSPPPTPSRIYGRKSRARSYMNTPSRLRGPSAASTSSTPSHYRRSLAEPMPSYTMQSLALDYELPVLLPETPSGSPSSSSSDLTSVASSSPSTNLSDSNRVEESGLDVDSDSDDEPVFISRIMPIQSSAFRDSDIMDELRQVRLDLENAREVFRSAEENRLKCPCCLEVMSQPFILCCGHTYCKDCLIRLANIYLNAKMNLVCPDCRTVQGCFTPIPNYFIQSHLDNMLRLEGIPTPSRQPLQWPLKFQSGPTPLPFPPSAATFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMH7</accession>
    <name>A0ABQ8VMH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_879316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="484" mass="53885" checksum="A2D2E71644F0CE2B" modified="2025-10-08" version="1">MIDTPLDEIPKINASLHATFATRKTFSLAWRQHQLLQIARMLQENHKAIADAIYADLGKPAFEVYMTELNLMLDRAIISAKRVPEWAAVKNLENHPDLPPHQKGWKPRVTPTPKGAVLVISPWNYPLILSIQGTIGAIAAGCTVCLKLSEVTSNYAGLLQRLIPKYLDQDAVRVVCGGVQEVTKVLEQKWDHIFYTGNGTVARIIAAAAAKHLTPLTLELGGKSPVIIDPEYDMELAARRVLWGKINNCGQVCVSPDYALVTPSTTASFVENLKKAYASFYPDGSLKSDSYARVINMQHFNRIKSLLERTQGKVLMGGGMDEKERRIEPTVVLVKPGDVLLESETFGPILTLLEVDDMRAACDYISANDHPLVLYVFTLNEQLQQDVFKATMSGNLIFNDTFMQMDVKVLPFGGVGESGYGRQVLENTFNCFTYERTSLDIPPEVEDKIYLRYPPYTEHAFEVECAPGLTVQIPESTPEEGLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMT0</accession>
    <name>A0ABQ8VMT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_825775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="182"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="369" mass="41313" checksum="B561A585918AD1D8" modified="2025-10-08" version="1">MSNTTSPPMAPFPSTGFDLSSIFDPFFYGVIISTGLFGISIVQLWTYINLSRDRWMFRVVVITVFFMDMATTYLDIGLLHNYLISHFGDLSIFSSYSNLLDMEILFTALIVFVVDLYFASRVYLLKQVHWSVVTFIVSTNVIALLLSILSVIISFHLAVFTRLGFTSKDNEIIVALENAMTTICEVVATTALAWSLHSSRTGVPRTDNILHKLHNYTITRGVLLTIVQILSLVFYVAQPTKLTWIAFHMCLSKLYFITMAAMLNTRSSLRRRLDRTITDSEVGRIIQQSGHDFARGTSFVLASNPDASALNDSNSLAEFGLTQISTPDTENPDDDHESVHSIKVPTALQPIVITRNRISTVDYHAPGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMU2</accession>
    <name>A0ABQ8VMU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_183237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047245277" evidence="1">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="79" mass="8302" checksum="3D098794BD727E1D" modified="2025-10-08" version="1">MKLSLQVALLALAAVGANAASRKKRDVAESAIAETTTATTEPLTLTATRVFNTLISEAPYMTAVTTEVVWTQYPASSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNG0</accession>
    <name>A0ABQ8VNG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Lysophospholipase</fullName>
            <ecNumber evidence="2 9">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_979292</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the lysophospholipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="2 9"/>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF33">
        <property type="entry name" value="LYSOPHOSPHOLIPASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00022">
        <property type="entry name" value="PLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8 9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 8 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044966265" description="Lysophospholipase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="PLA2c" evidence="10">
        <location>
            <begin position="33"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="607" mass="64024" checksum="10043C473C96DB54" modified="2025-10-08" version="1">MAPSLSLSLGLVSVLLVVKSSASLSDYAPNFTVCPDISLVRTFTPTSQILNPSELSFVAGRESSVIPQSWQSWLGNGSAIGYNTSAFSSFARVGLAFSGGGYRASQFGAGVISALDARNATAVAAGTGGLLQVATYLSGLSGGSWLTAGLYMNDFPMVQDMVLGSQPGWLLQEDLLDPDGSLGIVDVLEYFDAIDQSIDAKAAAGFNVTIGDAWARALSYHFLTGTNLSNFFDTSSHGAGQLWSQIASASFFANHQAPFPLVVLDSNGTFDLATESIPLDSPVYEVSPFEFTSFDPDISAAAELSYIGTSLFAGVPVDNGSCVTGFDQAGFVIGTSSNIFASTLSGGDTEVELVQALLGEPIEGESPGDAAVSKWPNPFWGMAPSNVAATNAELQLIDGGSNGENIPLNPLLVKAREVDVIIAVDGSSDTDDNWPNGLALLFSAERLSTLLGDSHQQLPELPSSTDDFIAQGLNLRPTFFGCNSTDVPLIIYLPNSPPLTGDAPFCNAPTTQLQFETSETQTILDQTYINTIGGFVPNTNFPDPNWGRCLQCATVDRSRLKATSIIDRSAFCTTCFTQYCYDPANITNSSELPNRNLTYAGPAVSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNM4</accession>
    <name>A0ABQ8VNM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF395-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_820422</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046513">
        <property type="entry name" value="DUF6691"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp_TsuA/YedE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30574">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YEDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30574:SF1">
        <property type="entry name" value="SULPHUR TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20398">
        <property type="entry name" value="DUF6691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="34114" checksum="9B2DFA80837F8749" modified="2025-10-08" version="1">MSTPTPLASFLGGFGLALPVHSLLVLNGSVFGISGFVHRAVRGNKEGLIATAGLIIGGIIIGTIEGRGPETSISPLPSLLLSGFLVGLGTKLSNGCTSGHMLAGLSRFSKRSIAATATFFCTAVAATKLHHSPTFIPANPPDYNMNTTDKTLLIAQTVPLIASVLLYAYASMSSHNPDTSSNSGQHKSPSVFRLVALLSTAVDFALALRLSNLTDPKKVTAFLLLPFHPAFDPSLAFLAIGAIPIGAALYHFFRGPEKPVLGGPWAIPKSGNVDTELLLGSVLFGIGWGASGLCPGPVVINLGRALATGSQLTSWLSWSVSFIAGGLCVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNT5</accession>
    <name>A0ABQ8VNT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTMP kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_820655</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="9">
        <location>
            <begin position="10"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Thymidylate kinase-like" evidence="9">
        <location>
            <begin position="139"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="237" mass="26326" checksum="2165F3B97BBF4748" modified="2025-10-08" version="1">MTRRGAFVVVEGLDRSGKTTQAEIMRRRIQEGGREVVCIKFPDRSTPIGKMIDSYLHSQSDLDDHVVHLLFSANRWEFASTILSYLEQGKLVLCDRYAFSGIAFSVAKSSQTPISTEGHLESSLEKLSPITLPWARAPDSALPSPDLTLFLDISPEVALTRGGYGEERYEKADMQKRVRNVFEEIGRQVSANAGEAGDGRWVVVDAGRDMSAVTEEMWGHVQPLLDGVDSPVGRLWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ80</accession>
    <name>A0ABQ8VQ80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_937700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="499" mass="55874" checksum="63DA0A8B1FF4D676" modified="2025-10-08" version="1">MAGKRLTASAFSLVFSEHSVTVSLIDVLMPLMCTLYFVQYLDKSTLGSSSILGILCFEHISLSHPFLTSSYRLSTVFYLSYLVFEYPQNLALQRFPVGKWLSLNIFIWSVALCCHAACRNFRELVVVRIILGMCEGSITAGFLLVSSMFYTRNEQMLRVGYWYLMNGTAQIATGFISFGVLHIQTSGFQPWQWLMIITGILSFITAAAFWFLFPDSPTTACFLTPEERVTAIQRVKVNQTGVGNKHFKKEQQVSLFYEAIRDPKTWGFALFSGISNVTNSISAQSPLITASFGFTYLQTSLLGIVGGLIEICTIWTGVNICARIPNSRAYIGAIYILPNIVGLLMVNLINWNDRIALLAGQYLNGLGTTSFVLMLSWLNAVTAGQTKKVTVNAIMLCAYCIGNAAGPFMWKQKYKPRNHVPWAVIGACYVSAITLLLLLRLYMSRENRKRDAEPQDEAADTNVYIKQESAEGDIVKMLKVDKGFLDMTDVQNRSFRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQX0</accession>
    <name>A0ABQ8VQX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalase</fullName>
            <ecNumber evidence="4">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_917976</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF1">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046025595" description="Trehalase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="745" mass="80898" checksum="721D68F2B8E03E66" modified="2025-10-08" version="1">MFTKFFALALCARRLYAIPAASTSVSQISVTTSIASPTASLGASIPSQYPLPPVQGWCPSQIFCAGAVLQTVNDAGLWTDPKTFVDKPTSNSSANVLADFQQLQAQDITEGDVEQFVDTNFGGEGLELEALVLSDFPQNPGFLGNVTDPLLKAWSQTVHGYWSQLIRSTNASALCPTGSSGSCESTLIALNHTFVIPGGRFREQYYWDSYWIIEGLLQSELYDIVNSTLQNFMDELELFGFIPNGGRIYYLNRSQPPLFIQMLSRYVTVTNDQSILERALPLAEKELQWWQNNRTVNVTSPYTNQTYAMARYAVNNTAPRPESYLTDYETAHGSGLNLSTSELSDLYAELASGAETGWDYCSRYLASPAPGNGDLTTLVVRETIPIDLNSILYKNHVLLANLYGSNSTAANSHLSQASLIREGILDLFWNSTKLSFYDFSLRTNSRNSLFSSATWYPYWSGIIPDEVLNNETNAFKAFSAVNMVLNRYNGSFPTTFLETGLQWDSPNSWPNLIMILLSALNELPSNITSMSLSVLSGNQSSFDLVPAGQLDLAESQLFGQPVMPGVNASQTGSSADINALNGTVVNGGNATDGEGWGRALQRMVANRYIASALCSWHATGGSISGLLPRLSDTELNVTQSVNNTGNMFEKFSTTDIDSSGSGGEYTVQAGFGWTNGVALWIASNYGNVLVAPQCPDVLVSAQIVGSSTTSTSSPAQQTSAASPRRFSAGDVMFWFGLLVVVQILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR60</accession>
    <name>A0ABQ8VR60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_724573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="111" mass="12642" checksum="A93060E231354B62" modified="2025-10-08" version="1" fragment="single">QVKLCSAIGDMGFLSNHVRSVKPLRPGMYQMLQYVMVFLVYGRFATVHTKKKLQINAVEAVRLEDFSVEVCTSGPIWIFFSVRHSHFFHSIRVNLQEALKVTSGTGSEEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRD9</accession>
    <name>A0ABQ8VRD9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="235"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="485" mass="53559" checksum="E3101804D09FF1F1" modified="2025-10-08" version="1">MTHLEQELVKKRQEKKAQKTALRRAITAARVESPNESITPIKRPAVGILEGETESKKRSKLSEIGGLVPAWKSILSTQGKISTAQPPLDVEPIDLGEFGQDDTADTLKIQRAGKSHQKEQKIAAKDIVEVKLESVDADLIANEERVTGKPAQPPKSSRRMKTADVPFVNAGDQDVWNTRILPALIEWSGTRQSQFNINADPELRSKVRDLWNIHLATIPPHCLDQKGNTILRCDHPAILSYAQNKLRTYRSHIGRNAMRIVSDYVANNASTVPKRQEIVQKLLRNNAFIYEKVGATRDLSSGAWRGELLMQAFAFYITWALSAPKNDLDSISDEPHFPVGALALTAAAVKWALTLWEPGYKITQTSTEEDQLEESGDSPEAKTKTKRKHSGTPKAPRNHTHSFGERWSSDCNKFQESTTVLAEPKWNLIFAAAEVHLLGVPNAGAGPGLKELQRDAQRAVAGMSVTSTGNSAKIEEEPDAIVLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRU6</accession>
    <name>A0ABQ8VRU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">sterol 3beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_755221</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="13">
        <location>
            <begin position="220"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="68"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="497"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1225"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1233"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1276"/>
            <end position="1286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4499098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1325" mass="147244" checksum="9696A484EF9AC5EB" modified="2025-10-08" version="1">MRVGTQTLIQALQALPWASDQDHEDDITSHDPSALTLVTDEEEEISNLFPLDMASSIHTIYRPVARSRKMSLTSRSRPRLHVSTLSPTEYSSDEIVQSDEEPDADDFEETTPKAPDPAAPSHLQLRSVSYVTQRQLGSSKLPEVVAMSRSGRSGSMATVRLQRRTKLAEKLRDIFELDGIEEVQAELPCWLLRSVLLQGYMYLTNSFLCFFAHMPSREDQILKSGSLNKKAQRTKRWVRHWFVLKNDALSWYQSSSDPYFPHGIVDLRYAISCEPSGERGFRVRTNQKSIVLSADSVPSREEWVKAIRKVMFKAQNMGDTIAIPYSAILDVDKSSALDFSETIEVKVYDKEAQEQFSIDSFFFAYFRDLPAALDQIRDAVRCRRTKGEASYTVLDTTATRNVAGPSGSTLPTSITSSNSLFRIPSILRPFSESRISSPSTTTSTTEPQHEEFTHITKRVHSSSFIPITTTLSPTSLGDVEDDSLDTPIASTIIIDSRHTYPPSTSGSPVASTHLSIPQRSGTSNSASSSNGSSWAVNVPHWLKVPRTRNLFGGVADTLPVIPPGGEVREMYTTAATTSPISAGSKLGNGGDLTYSILETPDAPIDDDIAEKFRNYFAYDERETLLGHFPGYIYRLLPVYGRLYISLNHFCFKSSGPLTARTRMALPLRDILSVEKSKATRFGQHGLIVIVKGHEELFFEFGAEDKRDAFVRLIERQIDDVRRRLAEGEASLPTPGQRDALILEELDIHSYSPTAEEHRLSTPENLTDSLLAPMFSSSTFLTFKPQKSLHFTFLTIGSRGDVQPYIALAKGLQADGHKVRIATHKEFKEWIEAHDIEYGYVGGDPAELMRICVENGMFTVSFLKEGLQKFRGWLDDLLKTAWEACQGTDVLVESPSAMGGYHIAEALAIPYFRAFTMTWTRTRAYPHAFAVPERKMGGSYNYMSYVMFDQVFWHAISGQINRWRRNILHIESTNLDKMEPHKIPFLYNFSPSVVPPPLDWPEWIRITGYWFLDDADVSSKKWTPPETLSKFIDTAHSAGKKVVYIGFGSIVVSDPVAMTKCVVEAVVQSGVCAILSKGWSDRLQVKSGETGNVEEPLPDQIYPISSIPHDWLFQRIDAACHHGGAGTTGASLRAGIPTIIKPFFGDQYFWADRVEALGVGSGVRRLTVDSLTEALRVATTDSKQISRANALGEQIRKENGVDTAIESIYRDLEYARSLIKRPIELDSDGGVTDIENSTIRQPPSSAEPKSGYSSNGSVHGAPSDWSVISERGDPSRRSSISSTFSGTSDDRPSKRSSIAAAMLSVLPNSLTPGSPRKRTISTPSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRY4</accession>
    <name>A0ABQ8VRY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_816010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12284" checksum="9B4C57B3BCC032CD" modified="2025-10-08" version="1">MKIIHRSSARTGVFRSGRITVVSSYIGCVDGSIQNASGMVNRGYCRCNFLKILLFTQNRLHSQELSHRKCSTSRGHAFSGYGSVSSGQLSPCVLYPMKPNVVPSPSRSSGLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSE4</accession>
    <name>A0ABQ8VSE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_908191</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="1755"/>
            <end position="1983"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="2163"/>
            <end position="2286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="423"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="2215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2293" mass="254328" checksum="538384DD15D08F5B" modified="2025-10-08" version="1">MKRKFGQPSLPTLFFRPDGVLTVPGYTFSKAVQWQDTGSMTMLAEGSSLKDGSLTLAKICPSHSNASMCLEREAHILNKIASNPQPFRPTLRMIELLTIPREHGDVVVLLLVHPGLNLLGRYLPPSKVNDLLLADISRPRHAPSHRDAFMMDIDISDIEQEMEAFDVVDLATFLEFAIQATMCLETIHKAGIIHREIRANAFHLNAHSNTVRFAHFGNRAVSLENYGSPSSLVLRTFEEGEKLKVKEALCYLAPEQTGSIETMAQDQRTDLYSLGILFWTLLVGRGQMPFEGGALELLHSIVQKRPMPVHEVRRDVPQVLANIVDKLLAKHPDQRYQSAYGLKVDLLECQRRLLATVSSASDDAELIPHFEIASQDRFMDFTMPLALFGREKELELIRNVIRHTNTSFSRHLSTSEGYIAISSSSGSQETGTAMSVGDDPESLSSSGSVSNSGMAPIDSAGNKSARYSPTQDYSSMSFSPSIQTSDGLRRAALIRKPRSSRAQVVILVGPPGVGKSSIILVNQAKWRSHGLWGQAKFQNADSAPFAALLGCLSSVLRQLMVFHMDVHRFVSALKDRLGPQMQNMPLLYQGVPELRDILALFGLNLDTPRETLSTRELRARFETLVENVFAVIADTRLFALFLDDLHEADESTLDVVSALFNSRSRMLIFVTIRSDKPDVVEKVRSMFSSRARPTWINLEPLLYSAIHALVSKSLHRSKEDSAPLSHFVYAASAGNAFTARSILTTLQRRNHITFNWELNHWEYNMTEIETSMDSTPKSDPTDLSFLVSQFREFPEEARKYMLWAIFFGETFKTTEVSLMMDWEDSSGSSGSDEDDIFWNLRRNAESSSSNNASRSSMRGMQLALVEGWLIQRARDMCSFAHDRYRQAVQAEANNLSEEARSKMSLKIILMMLHETESEATVDVYRIAEHAKNCLPLLLEHPKREDLLGLLIDAGEMAWARGAHELATQSFKSAKTLLRNEPWAENPKRTFSLFSKLASLATWKGDFAESNEFLKQCMAYAQQPEEVATVLRAQSQNNWMNKNFSGALEDTLQALKILGVEVNPAPTRREAAHMFERVKNEILAIGFDEILSIPRANDPRTELAVRLLNDAGTNAYWSPTPFSFAEVIGLTTIQMALRSGISTGTALGFFWALGGAAERRDLYRFSSDLAKLALRIADVHGSSGEKCRAYVLYCSLVSGYDNVHMRSALPRLEEALKYGSSAGDRIYTGLSSLYMISTRLFVCDYLSELVTAAEECLNDVQLTAPGEIAVLSQGTLNCIRALGGYTLASSPETAFDTDTFKEHEYLERVKADSGNEELVLNWYNAFKVVGLYCLGFVDDAAELGFYVYRTRDRHPNHRHIRYSLFFHSLSLIACLKQGGVSKEKHNRYLSQVNINQELIKKWVSSSAVNNSHWVALVDAELASLFNDPSTHKLYDIAVKQAVNNDWLLEEGLGLYLQGCHFVKCGVEGLGSELQRRGISRQSQWGAQGIVNHLNSVVGIRSQYPLKRPIFTSDVAVQTDSGLASLSSQMSSHPKMDISDDHQTTLQASHLAAILQWSKDISSDINLSSALQRLTEIATETSGSQNTCVVIAHEAGEYSVATQMIAPEPCLVYEIPKSIRSIGDPLQKAIIEHTLNSKERICHDDASSDMRFSSEAAQSPHRSIICIPIFSNRGQTFGAVYVASKYTFSQNIVTILTLLCQQASISVSNALLFRSVQAGTRENLKMIAVQRDALEAARKSREDALKATKIKSNFLASMSHELRTPFSSFYGLLDLLSGTELNPGQNEIVQTAKQSCELLLKIIDSILDYSKLEASAVKLEPSGFLVENIIADCMELLLPMAAKKLDLSFDIDPNVPPWVYADYARIRQVLMNLIGNAVKFTADGSVQVTCTLDKTHTSSSTPTANDEVSLKFTIQDTGIGLSPSDVELLFVPFQQADNSSTRRFGGTGLGLSISRQLVKLMNGVIAVESELNVGSKFWFTIPVKIYNSAESQKYLFDIENLRSGLTKPRPPHIVVCSASPVTLTLFGHILPGFSVVLASSIADAEIYLRNLGDRNPPVDFVIMDHQSEMQAEELAKFIDSLHHSTLNETKVIHLYTPTTSLSGRSVFGSNSPGVVKMTKPPRKARLLQTLAGLKNLPNAMPIAPSSDVIRAMDNIAAAQRTLFGNVLIAEDNPIAQNLLVKQLERYQLNVTATSNGNEALAEWEAHEPGYFSVALFDHHMPICDGVEASKKLRHLENKRKVSIILPIVALSADCQESTKQLCLSAGMNAFFSKPLRRTPPGDLTSLLSMFGPSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSH5</accession>
    <name>A0ABQ8VSH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_815321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="349"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="392"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="479"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="577"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="600"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="680"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="234"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="711" mass="78412" checksum="7A54C5026920439C" modified="2025-10-08" version="1">MPSDPPGSLRDEPKRNGRNVLDSINTSNSLAGSSKLQFIQNAIMTPFSHRKNESSSIISGLAPVIMTPRMMKAASTVSSKQPRERIVNSSMSRSRMDFATLGRAPLRLGLGTRRVTSRDLEIVEATEQLLHVEVPEPDGVASNVSLLRGFNATIPSAEQSKSRRRQMRSVDAPHIGLKKLGMNARGLLADEDDHEGQSVTSEDDVVMVPRSDATLRKGKRRGRESLSATKMLGKDELTRQRKEILRDKENINIKRSLVNNEIMEITHKIEALDDIRTKLEKDLIKLQEDELELDDELQGVKERLEFEQSGPARMSQSFQILHSSRRRKGPAFLPSEHDELPPGVAFMTLDSHTAPISALDFSEPYGTLVSASVEDSQPIVWDLLSGTESGRLRGHIGTVKCIQVEDTVCVTGSEDCSIRLWDLRLVDAEGSDGWGDEGEIVSLSDVAEEDSSEEGTRPNGIRNGMGKEQKEDAACLRVLEGHTKTVTTLFFEDNCLVTGASDKTLRQWDLTTGQCVMTMDILWAIAHPTSSTLANNLFAGAAASVGTFAFPMPPRADGSWDMYEDYVGGVQFWGYGLVSGSGDGAVRMWDMRTGQAHRTLAGHSAPVTCLQFDEVHIASGSLDKTIQIWDVRTGGVFETLKYDHPVTALQFDTRKVIAATGENGVKIYNRTSMQHSTLLTNGHTSPVERLRYMDRYLVTGGRDSTVKVWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VST4</accession>
    <name>A0ABQ8VST4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L36e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_817321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="70" mass="7826" checksum="FB0092CFCAAD1E7D" modified="2025-10-08" version="1">MARSNLSIGLNKGHPTTPIPKTVRPSQRKGIQSTKTKFVRSVIREVAGFSAYERRVMELLRNSKVSMVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT89</accession>
    <name>A0ABQ8VT89_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Indigoidine synthase A-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_978191</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="8">
        <location>
            <begin position="376"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="8">
        <location>
            <begin position="694"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="775" mass="82710" checksum="8E52EF476FBD2DA4" modified="2025-10-08" version="1">MLFRATSRKLSKLSNFSRGYLDSSLTRVLDVHPEVLDALASKKPVVALETTLVTHGFPYPTNYDLSNSLESIVRSTGAIPATIGIIEGRIKIGLEMAEVERLANPEKPGSVVKISRRDIAPAVALGSSGGTTISSTLIFAALAGIKVFATGGLGGVHRGGELSMDISADLQELARCPVGLVSSGAKSILDIGRTLEYLETLGVPVISYGPSKEFPAFFAPRSGFQVPWNTHSPNIAANILHTQSQLRMNNGALFAVPIPGKFEAAGAEIQLAVDQAVAESEANGISKRGKEATPWLLKRVSELSKGSSLASNIALLENNVRIGGEIAVEYQKLIEEQSCSSDYVTVGFSATSEQSSRPQPLASKKEPLATENNNASLLVFGAAAVDISANAFEMAPNFASGSTVPGTIAVSLGGVARNIAEASHRVSPKGSVLLVAPIGNDAFGHLLTEETANIGMRTDGLLLQKNQRTAVCNMIMDSHGGLTTGIADMAILETEQFQTEAIGMIKRVNPTLVIIDGNCSPEIISTVVKLCTEQGIKVFFEPTSVVKSTRILQAVENVSSPASPIDFISPNLIELREIFESANEKSLSSKPDYWTALDNFSLTSRYRMDLEHLSRVNVTDKDPSKGTLSFLLDQGAAQMAVRLLPFFRHIVIKCGDKGVLVAMRQSPTSQWRSEQSNIQRHQIINHSDSDTVVLSHFSALPVESLANVTGAGDSFVGALASCLVKQPNAFDSSETLTQAIEIAQRAAVLTLGSPYSVSPQLSMLEEAIKHLQYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTE1</accession>
    <name>A0ABQ8VTE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_978890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="155" mass="18178" checksum="C2EE8253E2BB914C" modified="2025-10-08" version="1">MSNEFVLPNFFTVFPASRAVDDFPPIANHIHQGHRVPDYRLGWVVTVTEAEELLEPAPEGREAINYYRYDILPPRWGTTEAKSDLQPPDLMLWSYETGRESHHKNEAYLLFYVAQNSTEDLKMVKEHKEELITRSIEALGLTSERQEKVKWYRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTM6</accession>
    <name>A0ABQ8VTM6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_893296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="66526" checksum="F362F80D723DFC2E" modified="2025-10-08" version="1">MTTRDTALIGNTALWRLKLLPNNPQRVLRSQRFYPVVPPGTTFSGVSYSILDPGSVPITQGVTSFPAQAKVGGSAKIPSILYYDKEGTVRAVGSEAMEPAFIEQAEEEGFIKVSWFKLHLRPDSLQLDFDIPALPGNKTPVAVFSDFLRYLFECTKSYIQRDTLGGHHWNSVEHNIDFILAHPNGWEVSQQGQMRRAAIMAGLVSEVESQERVHFVTEGEASLHFCINRNIPFKKDEGVIIVDAGGGTVDLSGYRQTPSGFEEIVTSQCVGQGSVFVGRRAHKLRNSRFGSEEDVQQIASIFDSDAKHTFRNPDDPVFIKFGTFRDRDPSVDIKAGQLKIPGNIVETFFEPSIKAIIQAVKEERKEATVPIGAVFLAGGFSANDWLFSRLKSELEPLGLTVSRPDAFLNKAVADGALSYYLDHFVSVRVARFTYGTNCVRAYDPYDLEHMRRRATMITAPSGRKVIPNVFSAIVIKGEQVHEETEFKEPFFLESRVRAAYREISADIIVYRGKSSSPQWTDLEPRMFSTWGTVYADVSAAVKTAGVHAGRFYHQAEFQIVILFGGPEIKAQISWQENYFFRSPATIVCEQIPQLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU35</accession>
    <name>A0ABQ8VU35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DUF1212-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_790221</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="603"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="8">
        <location>
            <begin position="168"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/Serine exporter ThrE" evidence="9">
        <location>
            <begin position="503"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="69566" checksum="8B13AE57E2E126FE" modified="2025-10-08" version="1">MTESKQHRNSDFLPRPSSTQPQQALPGANTVYGTSPSPAEVMKHKSTSPNGKSKEPPEFRRVNSDLEGGNVMRQSYSKKLGRLSKLSSIFSTNSLTPSTPRKGSDATLVGDDSGEQDKYTSFKGNQNRRRLSLKSGIPSVPVLSVLQSARQRSVITKHLEDIQIRQKFLLKLSKALLSFGAPSHRISSQLAAATEILGAEAEFVHLPNIIIASMKSSPNSPSARTYFVRATGAVALTSLHQVHIIYRDVLHDKIGAEEGTQALRKLLREHPIYPLYFRCILAFFGASTICATSFGGSFLDIWISGFCACVLQYLGLNAAHKSAMYANVYEISVSIIVAFVARALSNIPGNWFCYSAISSAGVVLILPGFTILVSALELMSKNLFCGSVRIVYAVIYTLFLGFGLTIGSDFYLVVDRRARKAYYVNSTPTNLTYTHGRFVMANGSIPFIPIQGVLGQANALNYEQQHLVKGCFRDPSWQWFRQPFPWWTLLLLVPLYSTLSSLGNLQRVRSVQLPVMVLFSCCSYAANKGASVVLPGRTDIVSAVGAFVIGLLGNLYSRVIGGTAFTSMVTGVLYLVPSGIAQGGGVTQTYRSSADQYSSGFSLALRMISVASGVAIGLFVSQLLVYLFGTRKNAAHFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUA0</accession>
    <name>A0ABQ8VUA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ferredoxin reductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_752977</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="70"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="349" mass="39486" checksum="81FFE7AE8A61B984" modified="2025-10-08" version="1">MRPTSIRLRPSHSNFRKWYSTIPNPSSRKGVRQLVIGSILSFGALTSFYLFFPDASRGAPTIKHGKLSPSHFTPCTITSSEPCGPYARLITLSVPTKLLPNPDEQRFPSIWSVFIKDDDIQVERPYTPLEGVDVEGRMSFWIKKYEHGEVGRWLHSKKVGDEIEIRAPLQTWLWKDDNVWDEVVMISGGSGIAPFYQLFHEIISRGVSSRTRFTLLHSSRSPSELPPSKILQRLSSFASENPERFRFRVFVDTLDSEEKQKMQLNVGRINKTALLSNLKEQSTSSKWLRWPYSRPVEAKVDVRKTLFLVCGPEPMVAAISGPYGRNFSQGPVGGVLARLGATSSQVYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUD3</accession>
    <name>A0ABQ8VUD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_82816</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047173">
        <property type="entry name" value="STRAD_A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014:SF21">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="53"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="210"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="43007" checksum="C54D202C6BD46171" modified="2025-10-08" version="1">MQALNTPPSFSHPILPSHRYPNMASLSNGVSLPQFIGAVEDHWQLFSDRSSDYVLGAPIGFGASSIVYAALYQPPNRQPVPCALKVLDLDTLPLRSWPLLQRETTLMSLSKHPNVLRVRGSWMDGHKLFIALRLMKKGSAADIMRYGWPGGLEEDVIKCILEQALQGLNYLHINGFIHRDVKAANLLIDDDGTVLLGDLGVAADLSEGSSHTLSSLSSNNEPAVDQKAASHATPSSPSNRVFNDSTSPSKAPRIGKRKSFVGTPCWMAPELIQGKQYDSSADIWSFGITALELTQGRPPRSREPPQKVLLRTIQDDPPTLDRDGGTYKYSKGFQEMVESCLVKDPSKRPTAQQLLQTPFFRGTKKQSYLINAILSRGFTSINKATRASGIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV47</accession>
    <name>A0ABQ8VV47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxidase</fullName>
            <ecNumber evidence="14">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_479026</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="14">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="14"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00692">
        <property type="entry name" value="ligninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024589">
        <property type="entry name" value="Ligninase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11895">
        <property type="entry name" value="Peroxidase_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 14 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="97"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4500258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="352" mass="36828" checksum="89D50C71C5CAC6EB" modified="2025-10-08" version="1">MLALKCANAVPHNNKRFACPDGVHTTSNEVCCQLFPLVDQLQSDLFDGGECGEEAHESLRLTFHDAIGFSPTKGGGGADGSIIVFSDIETAFHANGGIDDIVDAQKSFMASHNVTINPGDFIQLAGAVGVSNCPGAPQLEFLFGRPLPVAASPDLLIPEPFDTVDSILDRFSEAGFNASEVVALLGSHTVAAADTIDTTIPGTPFDSTPGLFDTQVFIEVQMRGILFPGTGGNQGEVESPVPGEIRLQSDSELARDSRTACDWQSFANNQAGFQNAFRAAMQKMAIIGHDRDALVDCSDVIPVPKPLPASAGPHLLPDTTHGDIEQACATAPFPVLTALPGPATSVAPVPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV69</accession>
    <name>A0ABQ8VV69_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_479376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="441" mass="48193" checksum="568A143E5B58A2D6" modified="2025-10-08" version="1">MTTLNEPCEKDAETVINADASPSKNGQSDEKRATVTYPEGGLQAWTTVFAIWLVQFSTFGYTNAYGVFNDYYVRIYMEGKYSSSTVSWVGSMQLWLVMSTGLVSGRLYDSGYFYHLIIGGSIIFVFCLFMLSLAQPGEFYQIFLAQGVGAGLGIGLIYVPGIAVVSQYFYRRRTLAMAIVASGSGVGAALQSIMLNKLFQRLGFQTAVRISAAFNAGILCIGILLSRTRLTPASSRDRNIFRYMKVFLREPQYIAVVLGTFFNLMGLFFPTFFLQLNANEKGIMSENLAFYLLPVLNASTVIGRVLFPMMVPLLGIFNIVIPSVFICVILIFCELTVTSAGGYFVIAVLYGVFWGAYVGMFAPMVGSLAKEDSEIGARMGICFTFNSFGGLIGTPIAGALLTPSFIWWQPTLFAGLSGAAGVICLAASRFWIARENGSQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV94</accession>
    <name>A0ABQ8VV94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_914359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF4">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="41172" checksum="CAA936604D34CA85" modified="2025-10-08" version="1">MLQVQHNAFRSTNFLKSTQALRRSLQTKHVKRPPLGFAFDIDGVLMGGPEPLPKARNALRILNGDNALHAKIPYILLTNGGGYTEYERAQKLSSCLDIQISPSQIIQAHTILKNYVDQYADKAVLCLGGIGDTMRKVAESYGFRKAYTTTDVLAWNSSIWPFIHVSESDLASAKPVDFSRTPISAIFVFHDPRNWGVDVQIMCDVLQSGGLLEGPYVDISTQQSNPIQVVFCNPDLLWKSDFPRPRLGQGAFKASFEAVYKMITGSEYPYVQFGKPTKPTYDYARRVLQNLMEESYGPGELPHMYMIGDNPESDIAGANAAGWSSILVHTGVYDPTTGPPTHRPSREARDVEEAVIWALENTLTGLKSEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVT0</accession>
    <name>A0ABQ8VVT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_875283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="65741" checksum="7A05B8EBD0E94A29" modified="2025-10-08" version="1">MNDPNVILLSLDADAAVTRVSSSVEVSTDSVLQQAQKFVRATLGTEVGGLVFFVLNEPIEINEESIMAKQFGHFSYKWIRWTKGTLREVLKTNPNIELVQVVAIRAQEFNELPPREFLPELPGGRYFQERPPKAPSSGAEPKEFAQSQENEKTRIHIDRPRKLNNTSVPIALLVPSFGNFQTNIKNIAPSDRAMLYATKIRHELCDIFHKEIDRERKFCSILSEFLGEDISNVTIGDFKTDGGVIHKYTAVNMNGAPRLFIKVKLEQTGTSDPCFQVSLDYLENTRRVRQNVVSRNEKAAAWFRARLPSILITHAGPNIQILGGVMTDRPQIEVLSASVPMYFHVSNQDLFLDLARILTALNILLADLGKLYDNPPPLNPLFPVQHEYPYPRRFKYGNQVITFTYLKRVDPIRLVFEVETEEEKLLYIKYTQRYGVEAHRKAYEFGIAPELLAYDDTLPGGWNMVVMRPIPRGYVETDGIRGGEEQGRVQAVVIAKMRPYFGEGFVHGDLRAANIFVDGERQNIMVIDYDWAGRNKEVAYPPDVRSSIDIWRPRAELSLRPIETQHDCQMLKHLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW76</accession>
    <name>A0ABQ8VW76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_810422</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="151" mass="17010" checksum="4C6923827BDE90D5" modified="2025-10-08" version="1">MGRMHAPGKGISSSALPYRRAPPAWLKTTPEDVIDHITKLARKGLTPSQIGVTLRDSHGIPQVRFVTGNKILRILKSNGLGPSIPEDLWHLIKKAVAVRKHLETNRKDKDSKFRLILIESRIHRLARYYKTKQQIPPTFKYDSATASTLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWI7</accession>
    <name>A0ABQ8VWI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinesin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_754101</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF45">
        <property type="entry name" value="PROTEIN CLARET SEGREGATIONAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="172"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="287"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="554" mass="62346" checksum="A7E0786194DB1284" modified="2025-10-08" version="1">MDEERAKRIELQEEQRALSLQLVASQQQELNRRAELNIISDELENSRKKHAREIADLEFDLQKKDRLLREANEDLRACRNDLEQERETVSSLKSALNAQSNAHLTLTAENRSFQTQFTALQAQYDELLRTNANLILDLEAERQEKIEMRKEATENEAVRRKLHNMVQELKGNIRVFCRVRPVLPSDIPPSSGYQPTNSPNPSPHEELELIRQELKADISFPDRRDHREINIWSSSESATGQERKESYQFMFDKVFEPECTQAEVFEEISMLAQSCVDGYNVCIFAYGQTGSGKSFTMEGGASNATKGMIPRAVDQVFRVAEDLRSKGWEYQMEGQFLEIYNEAINDLLGKHEFDKKKHEIKHDPKSGSTRVTDLTVIPLSSPTQVRALLSSAQSRRSVAATLMNERSSRSHSVFTLRITGTNAATGESCEGCLNLVDLAGSERINVSFGNGFGTAGSNDKERLKETQSINRSLSALGDVIAALGEKSERGDKHIPYRNSKLTYLLQNSLSGNSKTLMVLNLSPLASHLNESLTSLRFATKVNNTTLGTAKKQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWP7</accession>
    <name>A0ABQ8VWP7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_816988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="370" mass="38660" checksum="9A6C5949A6AD85A3" modified="2025-10-08" version="1">MNITSNFSPTLVFFCSAPAWLETEDPQALCSFAILHNVTYDNLDPSVTYLPQGGDGWDVDIKEGLDYEGSHAVASGDPDASAVFQFTGVAVYYFSPLWPYNVSTVVSLDGGNNITVNLMDMSATPASVGSPPTASSAARYGFTGLSNSSHTLSMFVLQGLNYSDPNVNGYIVVDGFNVTIDDGVQEVQSSGSSGKNVAAIAGGVVGGIVGLAASIAVFFIYHRRVTRLRAGGNPWEEKGVLEENSAPVYGRSGEAPYTDFGPPTHRDASKYSAGSAVALTHQSMYSQSEAGYTTVSAAAPGVTWAASTDPGSSSQGSGSTPSGSVAGKHSTYFSVKRLQRLTVANEEPPAPPPYAARSDDQGELENDVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWQ1</accession>
    <name>A0ABQ8VWQ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5-aminolevulinate synthase, mitochondrial</fullName>
            <ecNumber evidence="5">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_875488</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="15">
        <location>
            <begin position="216"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4499935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="715" mass="77008" checksum="1D43A9140AFE734E" modified="2025-10-08" version="1">MDKLSTLSRFKASCPFLGRTKTSTLRNLCTSTSTRFPSISLLTERATNCPVMGPALSVRSKEIVAGYASMAGNSDIEQIHKEKGVNIPVDASVEMCPHASAARAAARMADDLAHAAKGKEISSKAAAAAGCPFHKAALEQTVKATGVAPHPVPVSTASTSVSSSTRTGAYDYEAFYNTELEKKHKDKSYRYFNNINRLAHKFPVAHTAKVEDEVQVWCSNDYLGMGNNPVVLETMHRTLDRYGHGAGGTRNIAGNGAVHLGLERELATLHRKDAALIFSSCYVANDATLSTLGTKLPGCVMFSDKSNHASMIQGMRHSTAQRVIFKHNDLEDLENKLKEYPKETPKIIAFESVYSMCGSISPISEICDLAEKYGALTFLDEVHAVGLYGPRGAGVAEHLDYEAQLAHGENPDPIPGSVMDRIDIITGTLGKAYGAVGGYIAGSDDFIDMIRSYAPGFIFTTSLPPATVAGAQASIAYQKIYLGDRQLKQVNVRETKRRFAELDIPVVPGPSHILPVLVGDAALAKAASDKLLYDHSIYVQAINYPTVAVGEERLRITVTQRHTVEQIDKLVAAVDQVFTDLNINRIKDWKALGGRATVGVPGEDDVVEPIWTKEQLGEETGTTPKTLRDGEKDVVDPQGVFVARSRFDHLLGPISGPLRSGYQVVAPAVTTNTTTTSSAASVVPKTMKTGTKLMDFAPRARDIPVPPPSKLSAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX84</accession>
    <name>A0ABQ8VX84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_750920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051872">
        <property type="entry name" value="Cytochrome_b5/Flavoprotein_Rdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237:SF1">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="139"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="220" mass="23972" checksum="4ED7B3C8A572AF47" modified="2025-10-08" version="1">MASYLRSWLTLPTVASTSSEAIPTFQSSLEDEDEGSDTEREDNDAPPAFPSLNSAQRMQSIPTILTDSQLMPPPPDPKFRNRTIGVATPGGLAVPPTTTKPPVNPRKKREKVALAPGHSPLDWAALKSSGKDLRGVDSLMRIPPSVLKVHNTREDAWSAFNGKVYNITAYLLFHPGGEKELMRVAGRDGTKLFALTHAWVNVDFMLDSCMVGFLVSEPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXN3</accession>
    <name>A0ABQ8VXN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_810768</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a heterodimer with SLX4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SLX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10455">
        <property type="entry name" value="GIY-YIG_SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03100">
        <property type="entry name" value="Endonuc_su_Slx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027520">
        <property type="entry name" value="Slx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048749">
        <property type="entry name" value="SLX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050381">
        <property type="entry name" value="SLX1_endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208:SF10">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21202">
        <property type="entry name" value="SLX1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="10">
        <location>
            <begin position="19"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="320"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="428"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="546"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="603" mass="66598" checksum="37CCDD6CAD16933D" modified="2025-10-08" version="1">MRAGRQGNRSSLLSHTFPSFYACYLLKSVQTPTSKATYIGSTPNPPRRIRQHNGELTQGAYKTKRGRPWIMQLIVHGFPSKLAALQFEWAWQHPNLSRHIRDENGKVFTTTGRGLKQNIQILRFMISIHPYNLWPLHVKIFTPQALKIWDGLAGTQGKGKGKEKATNSAHAVILPRGFTHTVELEGVDGKLAGGTGRSMPIDVQDGAVYLCLTTHLNKHNDLIASTKLLQCSVCREPLNNYISDPLTHALCPHNSCNGTAHLLCLSQHFISQSLSGKCNLSDAPMVPRGGNCPSCFDFVLWGDVVKGCYRRSAGGAVSVEEDEEALEKMYKSDSLAEDTSSHDHDPGRANNDNAKGKKRKAKRVVSPRKKREREGCIESSTSSLGEEFDFDEVEEERYSDDPEVVGTSRRRMATSSPTKFKIGNAHLTIPTPVTPSAPTRTREPQTTLFSSSPTPRKQVRVIRSPKDYRESSEGELFDFDHVERLSSTDDDEAPKRKVGRPKKVLNVDGAASSRPTGTAKRRGRPRKDSLNVGLSSTSSKTPMKKLSNSSRRMLMSRPLGKLAAAPLESQRSDVLPLYLSDSDDDILVHTMSSLSVSSPSSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXU5</accession>
    <name>A0ABQ8VXU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mixed lineage kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_806363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054000">
        <property type="entry name" value="MLKL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22215">
        <property type="entry name" value="MLKL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mixed lineage kinase" evidence="1">
        <location>
            <begin position="263"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1072" mass="119637" checksum="806259022ACBCC52" modified="2025-10-08" version="1">MSRVSLEIGSIAPNFEGYTTSGPLKFHQWAGESWSIVFTHPDIEQRRIKIIGLSRNWPDESSHWTKLLQHYNRHPGSGRDVQIIADDQGKLSSLYGMLSQRDSNGVASNPNTVFLVDPMKNIRLVMSYPFFLSTGLTQILRFVDDNSGPLQDIPTHIFGLDAQGRGQIYDQAEISSRGGADSATVVKSAVDLVSNVEGTNVEGTTGSDGSSNTTVAATDYIQHAMSVMDSLADLGKVVPFVAPAFAIIKAIIAVEQRARDVDVKCTDLVQRVTFMLSHLPALKKIDVTNSTRQVIDRMNDTLKKSAALIQTYRKQSSIARRLSVHNKDRFTSCASLLSQCTNDLMISLQIHQSTQLDILTRPVPFDLEDEAATKFVATHGGIDAVKGNEALVKQFASEMKLTVDENVMEQLNTNISVVLQQNQDRLEQSLNESVSASVIEGIRGLAAQMNESAKEQTFVCVQCDKEYKESTSGEKSCSFHRTEYDSWSKSYRCCGSANPCQAGRHRSEHHDQYPYGNFFVFARNITGYTDTTEKWTELEDSNLETSKKMTVSVARLLRWKSRGAQPELPTVLIRVGSVSISEPYLFRTYNTKDLEVITKVVDITHQTVIFRTSHSEQEFAMAEWVLSAAGVIIGVKITAKSATSFDPFIQVCPIDITSCTLSGDVRSLSEGGLRSYKPSTPYVLPDIQRVSATIHEDAPREVRKDFKTRTTPNLPIVMKPVSDPPLVANPQYANPETDYFAGTISVFNKHKASSMEPISIASVAAFYRLVGEEKYQPVKSVELLDGITLPYSIDPRQTLTLQFGVTVPRSEDDVKVGTRWWNRAFVARQRPLRIKLVLTDIDEEECSLVLDYVCPVSNWEKADKEDLAYFYVDDLLTWKRYGVHIAKDSRMGPGSVKIGNESRGADWMKTIVYKALKTGESEIVLDIGADNDKGMPTAWSWKTWALVDLSCRRLYAFKILLTKSHGTAQSYACMGYVKCPDYGGFYEESRPIRYAKEVIKFPELKPYVPSRILLDDEFDNFVSSEALKPTVASSMTQSAIPDEVLQRLVSIDNSLSRLAISIELLVEIMKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY87</accession>
    <name>A0ABQ8VY87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_749047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="281" mass="31689" checksum="52D45FF33BD13F7D" modified="2025-10-08" version="1" fragment="single">PFVDADGRIYGLAVYPDDPGIKKCAQEAARLIQTERSRCSFSADQKEHRRGSFPALSTGVADGNGRTHPQNIVHNQANTSALNRLTSSKPFQRLSGFATGVFKTWAPRLYRYCEDHFNDLLSSDHSLVRIFHNSVLPAAAFNFGPRTICLPHIDFGNLPFNLCWIWALGWYNWKKGGHIILWDLKLVVEFPPGSLVAIPSGVCRHSNTCVGKKEVRYSFTQYAPGGNFRWVDRGFQSKENYHAGLTAAEAREEKLRKKARWKMGLELFSTLAELGFENELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYF7</accession>
    <name>A0ABQ8VYF7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_204751</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF30">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="668" mass="74537" checksum="DE7A41A8DA22B41E" modified="2025-10-08" version="1">MNPEEGRSRQSCDACRSRKVRCARENSDDPKQSCKHCITLGVPCTYEYQPKKRGPPNLYLRRLQEAAAAAAKLPEAAVDSELSVSPVSTSQSVVSPSLGPKSPFSETPINTSPTMSIPSIAISPSRYPIAADSFHAHYSSTNGNTISSPPFTNDLSHSPKAEENSAFPGSDSFNTYPLYNWSYKQHHSPSTIPPLSYYYRPHRLEEIAPRDTIYLIIALFFDFVYPLTPCVHKPSFMADLHARREERDPLFFALVMSTVASTLVQVPRSYLPMERPVVHKLAQTCHEASRHISVASYDPPTSMHVVIRYLYVSSQHFLTPNSKQDSDCVYHFCEGHDATQHAAFGEAAHIAVTLRMHEEASYDGLDPIECEVRRRIFWLLFGADKSMSILLGRPICLRDEDCSVHFPKELDDEYITPSAYLPQPHGKTALVSGLNYTSRIFALLGEILVRIRVDKRSPPQGQFATARLEEVQSLHQRILGALSLAPEPLRLKPVLSHSHLPPEYGGAGFRKATFDEVKDFFDNPNASRANALNPFLVMQANLYVTQQLVRFVIEQYRDELLLSLQGSLDDQKMAEDREAVASELLNILHSIPIQSIATNGPSLVHKVRFVASTLLDAVKKAEIAPASAARAHAYLWDFLSILSEIERNYLLDDDRDGTSSGDGMPMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZP4</accession>
    <name>A0ABQ8VZP4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="796"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="898"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="957"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="822"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="869"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1061" mass="119281" checksum="C8A36431E439530C" modified="2025-10-08" version="1">MATHTVPTRTNTVRYNLPDRRSPRGSMLGSPGSPEEGRAPSEHVPGGFDDNPQVEDSESGPVVSYGELMREMAPKLSNTSRGKGKRTVTAVVPRIGTTSHVPSSDNMNENRPQTGSVRPRVSNPYSSNQDANEILPSESASQVGHLEEEPNQGIDRGQSTVSMTSSIARAHQYQDTLRLRVALEMLRRDDIMKNNTSIIPEQGIEVEDVMPWLQPDLPQYQLSPPIDLHTSQIPPCTSLTITIPLSYLPKHPDAHQYAYNTLLMASPFNLAPGDLPSLAHPFSGAYTLETQLHIRPTRSYIDVLASTTPTTQYRTVPHPSLTSLRLRDPPGPPRKPSKGHHLAVLATTRSFPSSVTVLVAPFELQPAPSMLQHKPSHTKTYPKTYFDPGLTEDDFGYDTAHPNIRINWKKITETELQRYRKKYPEIGRKQSHSNRPGPSNSRSGPQQTNYQASQHRQGAGGTREQGNVNARPRNTPSPNGRNLSRDQSPPPPDPTHFRSGANRGVGAGGGPPGDPPPPGSGSSRDDHGSDDDSTRNHLQHSHGPNGPQRYGSEDPNASIEEKFEYDPTPRSEEEVLRASFQRYEQLIMFYLYGPPLNQNSAAQKAILQNIPKPGKWGGSSDYMEFEEWFMELIQWMNIADQCGPPTRFSETRGGYVLTAVDLTRTNTIGSFREGKALRWFRDEVQKVVNGLYQRFIHEASIAQVSDKFYEVTYSRKDGVKVMFSELKRWAACMPVPPDLYTFKKRVLLLVPQAMCNDMTRIEKVSAERSSVNEIMQSAISCERSDRTGKYYANAQNVNEQSQRSMRSAHKESTLPYSEDSEDKGKVKEHYKGQERSRSPKRLQVIDKRRYSVNDHNQIRHEHGQHKKDTKPMRSEDAPFTKPKQGACFDCGSLEHYRGSPQCKRAQTPPSQNPQRPKLYRIAEETQKGGEQLFRLEETTEAQEESPDEGIWVRYENSELGTPDGEPDPWGGSQYESDAADDDYLPSEDHQQHSSNDESTNDEHMHHMRDWDSFTVHWRDQLGERFGALIDQEDNQSSTEGYETAPEDAPQNNNDPTTTTAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W003</accession>
    <name>A0ABQ8W003_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator TACO1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_805300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048300">
        <property type="entry name" value="TACO1_YebC-like_2nd/3rd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049083">
        <property type="entry name" value="TACO1_YebC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532:SF0">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20772">
        <property type="entry name" value="TACO1_YebC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="YebC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TACO1/YebC-like N-terminal" evidence="3">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="TACO1/YebC-like second and third" evidence="2">
        <location>
            <begin position="99"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="28431" checksum="D46AABF8AE05479D" modified="2025-10-08" version="1">MFLRVPRRHISISSPKWAGHNKWSKIKDKKGANDASKSVAFQRATQDILVAARSGGVDPDKNTALAAVLKRLKAQDVPKDNIAKALAKAAKVKGFGEILTYEAIACNSVGVIIECATDNANRTVQTLREILNSRNARMASVGYMFTRGGVVVVGVENGPDVSDRLDAVTEVALSEGIDDFEALPPENDSLSRVKFYCETPALAELTDKLSKHPGVTILESEFVYNPTEKTAVSDQDAEILEDLIHALEVHDDVIRVTTSAGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W057</accession>
    <name>A0ABQ8W057_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_10147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF105">
        <property type="entry name" value="DAGKC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="385" mass="41723" checksum="EC4A4535CEF4F08C" modified="2025-10-08" version="1">MAVIAIYNPVCGDQTAKSFFEEQVLPICVTSSVLVTTVSSTERVNHVGELVLAELEKTPINEALTVILGSGDGTLHELINYLSSADIKGTRAGVTSVPPEIHLVLVPCEYRLQSVRSFLQAPDSHLLPLTLAITTLSSPPAAKIRPKAVASAVVISTSLHASILHDSELLRAEMPGIERFKIAAKQNSNKWYNGYAKLLPVASLGVVQLYDPDAKEFISHPDADEDNPVVDFYGPFAYFLSTVNVDRLEPAFRITPLVKDIPSANDASCDLVAIRPFSSPVVSIDTPEARDNFVSILWDTLQAAYQNGNHVNLRYDEEGKVTTEGEGPFVVEYVRCGGWEWIPDDIDDDAHIVCLDGDIVTIEKGGRAVCVAATPQAKAGFMVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1R1</accession>
    <name>A0ABQ8W1R1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_743692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="35013" checksum="AA0C73ACBABF9FA2" modified="2025-10-08" version="1" fragment="single">MMVLQPELVRDSEYYLPDGNTVIQVENVLFNIHRYILSRDGSAFEGMFSLDNIPQSDSAETLIMTNAENTRPSYSRSHLHHQHLSPEGSSDKTPILLSGDTAADFRSLLWALYALPAEVFAMPSTQAQITRLIGIARIAHKYAFRTTESWALSVLTICVCQAPDTPSGHDIHGDVEVDSEAGKSIVSSTELLIQLTEVAVLCAHDELHEAVEPIWADLLFAGQTQDIVSAMGLADRYKSQLRPLLGLAYYLMMLKGKEEWTKAASGDVEIDSDKTKKPRLTRDQRIRLLSGYYNLSRACEALSNNPPKLTHHPSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2G4</accession>
    <name>A0ABQ8W2G4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alternative oxidase</fullName>
            <ecNumber evidence="13">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_749471</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4501490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="42862" checksum="DE0B8C2E52479865" modified="2025-10-08" version="1">MLQHSIITFAPHVTRRVGYNALVVGSLRLTASRSFSSSAQRYNDLNDRQAKAAAVGPHKHDASSPSLSVTAINHNGDISHQNKGTHGDWVLFHPVYAPEELKSVEVLHREATCFSDKLAANLVKFSKWGYDLVSGFRHKTIPPGTDMTLEQLREGGYVLNEKQWLQRILFLESIAGVPGMVAATLRHLQSLRLMRRDNGWIHTCLEEAENERMHLMTFMTLRNPSIFFRAMILGAQGVFYNLFFLSYLISPRACHRFVGHLEEEAVATYTKCIKEIEAGRVPEWSDLPAPQIAIDYWRLDPNSKLLDVIYAVRSDETSHRFVNHSLANLDVNTDVNPFALQEPDMHTKGKKIAFERPESEQYFKETRDMLRKVSADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2L5</accession>
    <name>A0ABQ8W2L5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_805076</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CBP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012420">
        <property type="entry name" value="Cbp4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07960">
        <property type="entry name" value="CBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="90" mass="10134" checksum="DD5A420497AF61FD" modified="2025-10-08" version="1">MSHFPWLRFAGAAITFTGFGYLLMKATVPTEEELYNRMAPDIRKKVDAARALRLAREAEMKQQVAVQAPPTTLVDPDTIKPIWADTNSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W316</accession>
    <name>A0ABQ8W316_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_862374</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="58"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="314" mass="34801" checksum="1DA629DF934A9E92" modified="2025-10-08" version="1">MTSVAVPSNQEEWRAALESLPSTPQKIPAFFFAHGSPALVYARGFSGRSDFEQYQGPNGPLANFLKDFGPTLLQKYNPKAVVVFSAHWETLGERLVTEYGDENPLLMDYYGFPQEFYQLKFKSRGDKQLAEQIVGLYKEAGQLARTTSKLEPRGSDGRGFEGPGLDHGVFVPFRLMFGEEFGIPIVEVSIDSSMTPEANWKLGQVVKSLREENVLVLAGGLPIHNLRDFSSFAPDTAQSIHHSFHKAILDALQVNNTQERKKALQDLPKHAGFRACNPREEHFVPLYVAAGAAEDEDLKILNGLYGIPTVAFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZSR6</accession>
    <name>A0A9W8ZSR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">14-3-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_441488</name>
        <name evidence="7" type="ORF">C8R41DRAFT_251883</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000053">
        <property type="protein sequence ID" value="KAJ4465189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZSR6"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11309">
        <property type="entry name" value="14-3-3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="5">
        <location>
            <begin position="5"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4465189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="256" mass="28912" checksum="910E24BBBE351AF7" modified="2023-11-08" version="1">MPETREDSVYLAKLAEQAERYEEMVENMKRVASSDQELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKGNEAQVSMIKGYREKIETELAKICEDILDVLDKHLIPSAASGESKVFYHKMMGDYHRYLAEFATGDKRKESADKSLEAYKAASDVAVTELPPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQDSADKPAEKDEAADAPADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWU9</accession>
    <name>A0ABQ8UWU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_891792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046654190" evidence="1">
        <location>
            <begin position="21"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="133" mass="13954" checksum="2B8B76B6951B5541" modified="2025-10-08" version="1">MKFTTTTAFLASAMTYFVASNEVNAAPLSPLDVWDPTITSPVTGTVWVIGTEVNVTWSTDNIPPDGVSNGGHVYLAKEEVEVISLSPTFDLVAANGSFTVIVPAVVPDDDYQIVLFGDSGNIGPSFTIVAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWZ1</accession>
    <name>A0ABQ8UWZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Scamp family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_860880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000152">
        <property type="protein sequence ID" value="KAJ4463823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007273">
        <property type="entry name" value="SCAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687:SF90">
        <property type="entry name" value="SECRETORY CARRIER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687">
        <property type="entry name" value="SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04144">
        <property type="entry name" value="SCAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4463823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="255" mass="29023" checksum="8264DAC2BBE96E27" modified="2025-10-08" version="1">MSYNENPFASSHSLDTNPFEDPATSQADAARLESIRQREADLERRQRDLDQREQQLQHHGKNNWPFFFPLIYHDISVEIPEASRPLINRLYQLWLVLLGTLVLNMIACIFILIAGSSDGGRDVGAAIGYLFIITVTSFLLWYRPIYNGYMKEQALYYYFYFFFCGFHLLFSVYMIIGVPSTGSAGLIQTIQMFAGHHWVAAILGLVATVGWTLQGLGNAFYYRQIYTHHTAAGHTMEKAKTELASHGAKAYFTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY39</accession>
    <name>A0ABQ8UY39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenylate kinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_860859</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000152">
        <property type="protein sequence ID" value="KAJ4463818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="5">
        <location>
            <begin position="189"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4463818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="339" mass="38098" checksum="84D17A8F9C2236FE" modified="2025-10-08" version="1">MQIIRNASLTSHRMSIRTSPTRLSAWSAAARSFSSSSPASLFRNSLQPVAHDEAHSDPRHARMLRMLMFGKPGAGKGTLSGRLVKKYDIVSLSTGDLLRMHINDRTEVGRMAEEIVAQGGLVPDELMLQVVTSKLDRLHNKHWILDGFPRTFAQGELLNTHLNKQNTPLSLVVNLDVPDDIILSRISDRWVHLPSGRVYNLSYNPPKVEGFDDETGEPLTKRPDDNPEIFARRLEKFYSTTSPLLDFYARLSQAHISTPPHRHPHQHPHQLAFHTTPPHRLMMQSISGTTSDEIWPELERVLKDAFPGLKERVESADARRRHSLSDAIASASMNAAISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYN9</accession>
    <name>A0ABQ8UYN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PARP catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_857248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000118">
        <property type="protein sequence ID" value="KAJ4466068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051712">
        <property type="entry name" value="ARTD-AVP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45740">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45740:SF2">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PARP catalytic" evidence="1">
        <location>
            <begin position="279"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="404" mass="44820" checksum="23A7BA29360FE582" modified="2025-10-08" version="1">MQHYISNAHYPVYPTVFGFPVVVAMPICQEVVVAAPTDMHPVATLPASQYSSGQNMLVPRSPAVIAPSHSVRSTICQSSTMTVSVYDETGTTSNNPPCRLPGCSKRAHENPDGTFGDFCSRRHQRQCLQKGCKQEVYCSPDGALGDYCSKDHMNRGMNICIECFAKTVRPEHIFCSQTCMFITKSKGPILLKVPAGHKDFDDVRDQFYYSWTDPDSPCVKHIFKIMYPEEMTTAYHRYKRTIEARSHFAAFPPMSAGNEAQSWHGTNRECLLGERDRSRFCISSSCSLCCVIKSSFDIGFVKTNVARFGRGIYTSPSASKASSYSRNFGPAAAMKLKALLLNKVLIGKGHLIHGDHPSYREVTSPPPGFDSLVVGKGNGVNDDEYVVFTNDAIRPSFLVMYEDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ78</accession>
    <name>A0ABQ8UZ78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gibberellin 2-oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_857165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="191"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="379" mass="43644" checksum="415690BE1ADA5F20" modified="2025-10-08" version="1">MPALVNSNPPPPLLSWSEHPVTTESLDWAPLVIIDLAKFEQPGGKQELANELKDAVKLWGFWTVINTGISQEQLNRQLDIGYTFFKQPLAEKKKVACNFSEGNYFGYREPYRLVGKSDVKENMEMLNLPKYTPNYESYPRHDLIQAYKNEIQPFHRLVWDNVIRKLFILFAIILELPEDYFVQRHDYDKPSEDHLRYMIYHPRPAEDDAKIGGQWSAGHTDFGSMTLLFSQPVAALQIRTPNNEWKWVKHIPGGITCNAADTLSFLTKGYIKSTVHRVMRPPPDQANLERLGLFYFVRPGDDVPMVPAPSPVLIREGYLSEDEAKLASEGQNSDAVKGFEYVRARVKNVHTRNTRHVHDGRGMKEVFRLKNLEVPDFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZB9</accession>
    <name>A0ABQ8UZB9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="61393" checksum="BCB3004C2CAD8F09" modified="2025-10-08" version="1">MTIHSLPIEILEKIFHICFQEAEKPLILPDPYGPSETSTQNHLHAAANAFPPPHVCRLWRDICSSSTKFYPTLSLHYRHGDDNEKLSVVSSSSRLCAFLRLTAPHPISISFQITTEDQYGGNYLHEWYSSEEMVLAIGGTSGLIHILEHHHRWKSATISIPYPIIPVFFPEDMVFPNLKKLDVHISSSSNDRPDEPGRKLFGPHCTPNLCVTTFQQDHAWDLTLRWRSSSLIQVIILYSVYVECDDLRAFKECTSLHTIHFSSCTMLPSFNDVPSVQPIILLPNVNTVSFAWTLPNCYIKFTPLSFLALPKLRNLQLQWNEGLELEVIKLSERSSFKLETLTLIQAQRGVYRPPTEQFVSLMTRFSEADSINQSLIGLELNHTDAKWDVNEFREVMEVLSLGKRSSPSASEDTQKSGGLNEIPHPDRFPFLKQLTIAAYTIPDHSAFTAMLKSRRCQSPSSSLISEVQESATLLRNSPRGGVALEILRLRCSKSAFLEEEELLKHLETFSDEGLKLFYEPWVGVSRKNLTLWSHPSYELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZX5</accession>
    <name>A0ABQ8UZX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_779893</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18573">
        <property type="entry name" value="ABC_6TM_ABCB10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="102"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="417"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="656"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="678"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4467281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="701" mass="76009" checksum="081DA8917B5A6CCB" modified="2025-10-08" version="1">MLRVPVCTASSRGIYSLAVLRPRCIHSILPTSLIRNTRLFTGVGISFRTRTYSTQSTPRKSSELVKPGILSRFLPSGPSVTASSFRKIVALAKPERKPLTTAVGLLLLSSAVTMSIPFTIGKLIDFFSSVNPQIPLGLSIWQASGVLLFLFSAGAAANAGRTYLMRMSGQRIVARLREQTYSAALHQEVEFVERGEGDVLSRLSVDTTIVGESVTQNLSDGLRAIVMSSVGLGAMFYLSPTLTTLMLCVVPPVSFGVVFYGRYLKRLSNRTQEAMGEMSKHATESLSALRTVQAYNAQPQEEQKFHEKVTNVLNLAKKEAVASGIFFGSTGWSGNVTILALLGYGGSLVSQGEITVGDLTSLLLYTVYVGSGLQMLTCSSIMRGIGAGNRVFELLGREPAIPTNSGVVLDPHRRGPVRFERVGFEYPSRRGVEILNDFNLEIGVGESVAIVGTSGSGKSSVQSLLLRYYDPVRGKVTFDGQDIRELRLDSWRSAIGIVPQDPVLFTGTIASNIAFGNPTATREQIEDAAREANCEFVWGMPKGFDTEIGRLSLSGGQRQRLAIARALLKKPAILALDEATSALDANSENRVNDAVDKILRKRQTTCLFVAHRLSTIARAERIVVLEGGRITESGTYRQLVNDPSSRFRTLMAEQLHAASTQRPTTSPPSREPASEGAEVTEPEEVEEVEAAKESPPSNNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V076</accession>
    <name>A0ABQ8V076_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Histidinol-phosphatase</fullName>
            <shortName evidence="8">HolPase</shortName>
            <ecNumber evidence="3 8">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_779356</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3 8"/>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12110">
        <property type="entry name" value="PHP_HisPPase_Hisj_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="HISTIDINOL PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039:SF0">
        <property type="entry name" value="HISTIDINOL-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="9">
        <location>
            <begin position="5"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4467792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="315" mass="36575" checksum="C0CF4A8299FB9ED8" modified="2025-10-08" version="1">MPYSHHSHSGQFCRHAAGSLEDVVLEAIRSGFEVYGLTEHVPRYRIEDLYPEEAGMDLQALHDQFDAFIYEAHRLKARYASQITLLVGLETDYITSIDLDQLDALLERNRGRIEYIVGSIHHVGEIPIDFDVDTFKKSLAQQPGTSENERMENFLCRYFDVQFHVLQRFHPEIIGHLDLCRLYHPEIRLSDYSRSWKRLKRNISYAIEYGALFEVNAAAFRKNWDTAYPAEDLLKVILQDGGRLALSDDSHGPHAVGLNYRRLLEYLRREGVSELWYLQVSESPNKVGRNIQAVKAPGEWWNHPFWNKQWGEIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1R9</accession>
    <name>A0ABQ8V1R9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">General substrate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_984447</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4469649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="35653" checksum="37180B22185D6D79" modified="2025-10-08" version="1">MKKLSPNAYLRRKPTDDIELLHELAEIETAIEEECEARKGLGWKEAFFQWCGAVKILPGILHTLWGGPLLIDAGNFRYYAPQIFTSIGYTGNKNSLLASGVYGVVKTLAIHHLTLLSIVGRNVNLHLHLLELRLLAGNCQSLYPQWEWATCFSIVGAIIKTHPPPAASQGMAVMLYIYVCFYSMGWDGVLSHGSMFRISSLPDNALSFGCCQCFAVVMGTSSSLIRRFQSNSILDSKFYKMFATVNIGAIGTFSLIIPDTKGRSLEEMDIIFGSVSAKKRSADVAKFEHALDNGPEIGSTRSNDYYIRNVTILMSLFLCTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1U8</accession>
    <name>A0ABQ8V1U8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-P-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF3">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="26"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="39317" checksum="CC79EEDBB70EF5FA" modified="2025-10-08" version="1">MALGIQGSSITKALVIRKADAKSNEGYVNDVVLEEIPLRQLNPGEILVKIHAVAFNHRDVWIRKGMYPSIQDGAVFGADGAGVVVAFGDSRDDGMLNQRVFLLPSHGWDDHPNAPESQFGVIGGVRWPPLGTFAEYVIVGKDQVIPSAPHLSDTDMAAWPLAGLTAWRATMINAAVQPGQNILITGIGGGVALAALQLAVAQGASVYVTSGSQEKVNKAVELGAKGGASYKDASWPKEIHRLLRKNSPAGFPAMLDSVIDSGGGDIMTSIGSILKQGGSVVCYGMTAQPKVTFTMRQVLRNQKLIGSTMGSTQDLRDATKFLSKHKIVPVVSQVIHGLENAEKGFEMLRSGAQFGKVVIEVGGTRDAKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2E0</accession>
    <name>A0ABQ8V2E0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_897993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="33544" checksum="F63A6554F3AFBDF0" modified="2025-10-08" version="1">METYWHEKEKVSILAIYAPNTDTAANATFWDKIREFFVTHPRIKKPDFMLGDTNFVKEPLDRLPARNDPTAVTDAFDELKHSLQLEDGWRNTYPLTLKYTYMQKRANLITRHSRLDRIYTTPSNMSQTFEWKIEQAGINTDHDMVSVRFTCETAPMTGKGRWIVPIHLLYDKAIQEFITVEGKKLKERMNQADIDEQWNPTSNHQTLWSEFKQRFICLARERAKIVIPQLTKEIATLEARVDTISNDPLLDDMERSLSTTILKEAIAALEEQRMKSTRSTAKGNFAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2T6</accession>
    <name>A0ABQ8V2T6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_803768</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4465706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="470" mass="53097" checksum="4BCBDA5852552E94" modified="2025-10-08" version="1">MLNAIPTVGPNGFLSGFVGTYRFFTNAKDILQEGYEKYPNRIFKVALVDRWAIIAPGRMMVEDLMKATDDQLSMIEAAAETLQVEYTLSKEVVLHPYHVAIVRTPMTRNIATRFAEVRDEMVSAFADLIPAKDDWVKVPAYKMSFQIVGRTANRFFVGLPLCRNSDWLDLNTNFAVEVFISAMIINLFPSFLKPIAGRFLTRMPSSMKRATKHLAPIIEERLAREDEYGTKDWPGKPNDLISWLLDEAKAEQREVSDLITRILAIEVAAIHTTSTAFCNALYQLAAHPELVVPLREEVEAIVEESGWTKEGVGKMRKLDSFLKETLRFSGGGGIVNNRKVLTDFTFSDGTTVPAGTTIGVAAYMHHHDEAQYDNPYTFDAFRFYNMRNREGESIKHQTISPGLDYITFGNGRHACPGRFFAVYEIKGLIAHILMSYDVKLETEGVIPPYEWHGPSMDPSSTGEVLFRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2V1</accession>
    <name>A0ABQ8V2V1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_898476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="16"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="194" mass="22538" checksum="B935F0CE80AD8DC1" modified="2025-10-08" version="1">MEHARGDGRGSYIWGRSVHNTWHDMFTLLEIHHGLQASNLNHIWLLQHLFLPMINEQLTFWAKSWNTRSPEDMFVFDSLVNGVRGDDLDQFTMTDEELEVFGVDWEGLQDETLLRNLRMHYSHEGSGSWLGHRGSPPDLNEVAVSPPSALLTQEQVIFLNQQLQHHVRLPREQEVIQLWIDALVIAKTMYPDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Z7</accession>
    <name>A0ABQ8V2Z7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_897749</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045475320" description="Nuclear pore protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4471638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="761" mass="83190" checksum="28B0169900616A55" modified="2025-10-08" version="1">MALGVVLFRKLFLCLVQCERFTYMGVTSTLHRVHLHQMGHDTDVSSFLRHAYQQNLISMIEHGRKETQESFYHIDWEVKKKRLFEQLGASVPVAASTMSLVSSSAPLSLQMHTKMLAYDRTIIALNSAGLGGTSFPIIHALIDAANNNNQIVFMFNVLANITQEPPSLPPLEHASAHILDSPVFKRKYAKAYLTLHTPAISLRKQIVSGARQALEEQYHTIIQRTVHSHPFEAQPGGNPSTANLVRAFCALVKGTPVSEAFQVLMRIKDAVDTRKPGFIDAFHIWAYSTERSLPRSVRDQLAGAQTTDPFKLAFIPNVTTTTEDWLWMQSALVNESSSDENNESSLASLTKVLLAYGERHFEPATGTGGKDQGFGLAIASLWDHDSGGSLQVEAIHLAIALAYHGLLRVLSKAEGSDYIRQFVKIDAKEGLQYVHILPLSADHSPPGVGCKQLEVAWELVKRITVMANEGPMWEELVGGVRGDGTRFMSGFFPGVIPTHLPLLLPFSLSSFGPPTLQTSDYKSQILLPTMSSLLSNSHLTKAIKLYELAGEYDTVVSCLAQALGNLVTSGSMTSGLGAEGMTWSATGDQQDRTKELEKTAREILTVYKRLGRGTGLGVSGPSGSNPGGKDRDVCIKLLKISKATLETIESTALVPLDVATTSGKESKVDVMKVTKKVEEFTQQHEALQRCLPVSLVLCMDALSGITSKMKSVHAGEAQRHATLAILRKKSRALIVYVGLLKYQMSPEVCGYLARGDVEIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4D4</accession>
    <name>A0ABQ8V4D4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ASX DEUBAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_731541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14926" checksum="7CDA3D15007FC73D" modified="2025-10-08" version="1" fragment="single">RRHSSSQSRKPPAPHALSPQKMRALISLYHQSETFITPENLSERIDQAFTGEKTGNLAFRSQPGIDTLSTFYNEAKSAPKFSEWDREKMKFGHGVWSQATYSRREWKVIEALYGVDASGSLEPLPGLEALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4E4</accession>
    <name>A0ABQ8V4E4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_849770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4472645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="32605" checksum="7A8BE6808B0E657D" modified="2025-10-08" version="1">MSLPSIILNELAKIEPSAEFTGRLGGRVESSSEKVYFVKLGTSDEVEQYLGEADSLKAINTGAPGLAPRVFATGTFENGRPFFISEYKDIRNLTEKSAVLLAKRLATEMHSYKSQFGFGFEVPTYCGATRMKNGWYDSWEKCYSEMIGDLLENLKKRGRYEKLCAKGKSITKDVIPKLLGPLQIEPVILHGDLWSGNVGVDSATGEPVIFDPSSFFGHNEADLAIARIFGGFSASFFAEYHKHLPKTKPESQYELRGHLYELFHYLNHTVIFEGGGYEFNALRKMDILIDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4R7</accession>
    <name>A0ABQ8V4R7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_710777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="19"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="36134" checksum="076598D8AB2063C2" modified="2025-10-08" version="1" fragment="single">LRSFLSALLGYDPTQDDTTDGVLGVVRAHYGCIEAQGRGSLHCHMMIWLEGGLNPNEIKRRIMENPVSDFCTRLVQYLDDAISNSVPPLPESDITVPSDVKHPCLLRGTTMQGFDRTAMESDSAIQKDLHNLVLKCQVHTHTGTCYKYSHGDSQPIECRFGLDASNFEPVSFFNPENGELTLRCLDGLVNNFNEFIIHAIRCNMDIKFIGSGASAKAVLYYITNYITKSQLKAHVAYAALERAVRRLDEQNVDDDPLMVRAKKLLQKCAYMMISQQELSAQQVCTHLLGLEDHFTSHDFRNLYWVPMERFIDLQVPSPEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Y5</accession>
    <name>A0ABQ8V4Y5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_905237</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045260">
        <property type="entry name" value="Sec12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284:SF0">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3 11" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4473489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="397" mass="42472" checksum="ACA8430ED4C3B798" modified="2025-10-08" version="1">MRVAHTSHALPAFPVYSSAFLSQNELVVGGGGGATKSGIKNKLKLFKVAKDRSAEQLDEFELAIGEDAPMSMATDGTTVVCGLNSAPELLGKGENENCRVFKVDDGKLSFLRSQGTLSVKPDDLDYQKVTVLSPDGYLAVAGPNDLSLLLYPSLMPAAQSLKVDKEIYDATFTKSTLIVATTAELRVYTLPETKSVSPSKPKKGKQKVSTSLPSLVCERVIAIPSSLGGPSGSSFRAAKIHPTLGTILYAVANTIPNRSRGKSTARQAHVLKWNTENWTVEKTRKVGDRGITCFSVSPDGNLLGYGSSDLSVGLLDAATLNPVSTILKAHEFPPTTLAFSTDSSILVSGSADNSIRVINLPDQVRGSNWSFFMLIILTLIVLLLAYTAQRYSNTLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V573</accession>
    <name>A0ABQ8V573_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptide hydrolase</fullName>
            <ecNumber evidence="13">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_552840</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053974">
        <property type="entry name" value="ERMP1_1-A_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF22">
        <property type="entry name" value="ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22249">
        <property type="entry name" value="ERMP1-TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="605"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="141"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum metallopeptidase 1/1-A TM" evidence="16">
        <location>
            <begin position="412"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4474799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="908" mass="100016" checksum="0AC1BE71D47A29E2" modified="2025-10-08" version="1">MTSNASRQRFGFFSSLILLSPILIGAPLYSYREHTYLPEPLHEQYDPVTNSPQISESRILEVSRILSEDIGFRTPGTREHALGEDWLWDQVTRIKNDCDDMVRRSSRRHLECEIWHQKGSGSHRFDMMGARLYKTYVNLGNIIVRLSNGTEASKEHSVLVNAHLDSTLPTPGAADDAICVGIMLEAIRVLIESKDWEPRHAVIFLFNNAEESLQDGSHLFSTQHDVAHTVRAVINLEAAGTTGRDLLFQATSKEMIEAYSHVPRPFGTVVANDVFSSGIILSDTDFRQFQQYLGVTGLDMAIVGNSYLYHMRKDVVENIQPGVAQNFAENTLALLLHLSSPPINSPSISSLTAGFTKPSTVYFALFGKFWMYSFSTARIIYAILLVDAVILVTATARSPSRSALTTLGKPILAVLFAFVGSLLGTNAIALVMRFILGKPLSWFRSEYSAIVLYGPAAILGALISQYPFTAVTELQAYHATLLIQSFLAILIQLLGIGSAALFFLNATSIWVGLAVTALLGLISVRTERVSLVTYAISSFIPLFIGTSSAYLTLEVFVPLTGRIGADAPADNLIATIVSIVGALGCPLFVPFVWRFQNSNTRVLNRMILAMVLVTAIPIAVFSVREPFDSMHQKRVYVMRTENITTGEHHLHLSTSDGAPNFEYLVYEVAKQFSAPAITEPSDNASTVAAGIPVPQPEPILMDWYNSDWDPMFPFSLFLTPYKIPLPVDADYVSPWSLKSGQNRGTGFTISALDDVVDVEAGTRSLKLVIWHPGLIWTVIAFDAHVLEWNLDDEPPNEYTRHHVKEASYYGSDTWSIDLVIKIPSPPIFNSKATNSDSHVGAGEILVNFIGLEEEGMWPGKKGILKEKGVKEPGLALKLFSTLDAWIEKETGGKVDALLLGCVAGVQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5H0</accession>
    <name>A0ABQ8V5H0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_856398</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="9">
        <location>
            <begin position="129"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="9">
        <location>
            <begin position="432"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="319"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="516"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="636"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="745"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="710"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="758"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4466799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="802" mass="81926" checksum="BE8656AAAAF4159E" modified="2025-10-08" version="1">MELPIPASFNAIHAASLATITKYTQYAAGPASTVCATKHPARQLSDLSADLSSSTANSTSAESPDSSDSNSVTSPSIQTQQLVMELARLHKNSDTVLDPQLDSHSDSASPTLTNQSQADKLSPVVRQPCENCHTLDTPLWRRDSEGHPVCNACGLYAKAGKGRRPATTSTTLASHSPGPSESQTTPAPNGESASSLSAPAAGSPANNKNISPARSPPSVSFFNSHQLPHPALGSPHGSSSSGLHLPHQLSPVVSGSSASTNPIGVPPADPAPTVIGPGTCPGDGRCDGTGGSKTCSGCPTFNNNVNNAFTMCARVEEGDRKRSPATSQQQHSQHYTTGVATSLHHPMPPQQISQHTGSATAAGASPSMMSGVTPGGDGSGSVDPNNHNGGGGGPTGSGNTNNFGGGDGSGGGGPGTPGGGNGNNNSRKVRAAVGALCCANCGTSATPLWRRDDVGNNICNACGLYFKLHGTHRPTSMKKTVIKRRKRVPAAAGTGPPIPMRMTDQAAAEALVAVGRAGGSSAPGEESDDHEALEGEQPKRKRPRKSKGEGVYEGDLHQWTGEGGSPSMHHHPIHRPHSIPPMGFMHPSLQRPGSSSFNHGGGMLPGINSMDVSGGDPSKGLGGMVFVPGGPGVPGTAAVAGGSNSPGYIRSGSPHAHSPSNGQHSGALLLPSPQGPGGMFQPLDVPGGSGTGSTMVAVLPGTTFALIPSVSELERHYAELRDQKMRMEEILERTEKMMQGIKRGIDEMRGGDSGEVRSSSAAPGSTPAPSAPIQRPPSSSVSEKDRRESVWTVVDATNRGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V649</accession>
    <name>A0ABQ8V649_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_897266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="127"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="284" mass="31309" checksum="2BFCA388191BCA79" modified="2025-10-08" version="1">MHSSGHSTPVPRRSAMKHSFSSDSPHQSPYTETSPLPSTSSFPLDAPSPLVSSSPATSAVHRISSSTNIATQSVPSPYVSMPQTPVPGYTPKVSFDTFENPVASMFSFTLRAKSAGYKRTRSTRVFLCASSADESGREALDWSLESFVQDGDEFVVFRGIEEEVLDKDHDLVREDARALMAYIQAKSQEYDPDRKLSIILEYIAGKVTDALDRLIALYKPDSVVVGTRGRKAWQVGIGKGTMGSISRYCLTHSPVPIIVVRPERKVKKTVEKRRADPKRGTHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6W7</accession>
    <name>A0ABQ8V6W7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_848119</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="222"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="379"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4474165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="454" mass="48836" checksum="DE2FF50C3B5D8E93" modified="2025-10-08" version="1">MAHGRRLSQSLIHSPESAANFTAAAPPSDAEDWLTLWQASFAKDIIDSRIVAVDGQISVEEACDILLSEDIPCLAIKSIDHSVSGLFDFSDVNAFLTLAATKHTFSAEAVQEKQRVDDIFTAARSGHVPVSIVSNLSEKNPLHTLPYDATVVSLLEVFARGAHRVLIQSNSSEASEEEFIGIVSDRRLLTWFLSFAQQSESESLRTYLSNPLNSFSDSLPSLNLFASVVATVSTEPVLEAMKLMSDEGVSSIAVLEEEGGTLLSAVSVTDIGKIVVPSQSNQILSLSIQHFISLIKGPDGSMDGQDRYPVYSVLPTSTMLYTMQKLLATNAHRVFITQDSTVASPLLSPKSSGNLAGLVSVVDILSLFARLAKVKDVDPTRMQRHRRASSVSSQASSKESDRSRSSSRTSVRRASSTKTSQIMGSNQKRRSSSSTTTSTTGVVGDTATASKFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V724</accession>
    <name>A0ABQ8V724_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="39921" checksum="70FCA1E232F89E95" modified="2025-10-08" version="1">MQRIIHSEDTLEMLECAVDLRFNQGKDRVSLWVLGLWQKLSTTCKYQENWRDAYTTVEQVVKDPIVAVEFPTAEHVFGQQKWNNNVKVGKPVMIGDNVTQSMIQVMQAQLGKLRRQGSRSWRKPTSLLHCEMSRPESRPIRASNCGFKPFNISMRLYSVLTLGKVQLLMEDSILCIPVSMNTIGHGIFGDKLWEHDHRFLEQLVWFTTLVPDIVKEPILSNLLNPAQEVAYCDILEAVEAEVEGLDGPEYDAQEISTSKALYEQPTAEPPPVSDDSKKPNKLTSAWASFGFATQTLPSKTSKKHTADFKVNDSESKKQNTGRMLSGSQVGTSKSNQSTKTLREKVKAGIYDLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V784</accession>
    <name>A0ABQ8V784_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copper transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_844692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4477985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="26473" checksum="F3910863B5E1DAF3" modified="2025-10-08" version="1">MGSAYEEDHVLHMSFRGTHILLPGLRLSSFGSFTAASLFVIAICFSERFLSFISEQEWRPPFVARSRWQNAFWKTALYWVITLLRLLYMLCAMSFHFGLLLVIVTSLAVAHLLIEVRKDIQSSDARGAYSSIEQPFHDDTPDHHLPSVRLRSKSKPNGIFIHPQHSNLARADAAALQLGLGGPTERVSGSVYQLKEEPSWKTGTGKDVARALLGGSHQQSNTNQHSFDVGSDSDCSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V785</accession>
    <name>A0ABQ8V785_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_772696</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF69">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="43"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="545"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4477981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="569" mass="62244" checksum="0E2A54E67D83B73F" modified="2025-10-08" version="1">MTSLSETPQSSSPAGSKVNIRATIKNGVPTYLNLSGDALLRAITFTSTCAFLLFGYDQGVMSGIISAPQFFRIFPDLNPAVSGSDHSSTMQAFYTAIYEVGCLAGATIALLFGNKLGRRRCIAIGATFVIIGTIIQITPIPGHKAGHQFVIGRIVTGFGNGLNTATVPSWQAECSKAHNRGLHICIEASMIATGTVIAYWIDFGLSFVDNSLSWRLPIGLQITFAVLVLIGIYHLPESPRYLLSTGQIEEGTHVVAALAALSVEDEETQLQKRLIIEALENVGELKIKHVLTGGPSQHLRRTLIGASSQLFQQIGGCNAVIYFAPVIYEQYIGLDRRLALILGGVNSTVYALSAFGSYPMIERLGRRKMFLWGTAGQALAMFLASFCLIPADLHGDKGSGANKGAVVGLFLFLISFGCTWLELPWLLPAEVNPNAIRTNANAISTMTNWSWNFAVVMWTPPLLNAIKGFGTFMFFGVINLCFFPFIYLFYVETKGRSLEEIDIIFAKAYTNGEWYVKTGHEMPALSEHEIERAAVEYGLANDVEKRRHEFEHPPSVREEYGADEKQTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7V3</accession>
    <name>A0ABQ8V7V3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase, V1/A1 complex, subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_844003</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4478932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="25585" checksum="2E17BD6C80494D57" modified="2025-10-08" version="1">MSRPMNDDEVLNELNKMVAFIKQEALEKAREIKVKADEEFAIEKAKLVKQEQLAIDAQYEKKLKGAEVSQKIAQSTLTNKSRLRLLHRREEHLQDLFSTCRNQVVTLSSSDTDAYSEFLAGVLSQGYLYLMEPSVVVHCRKVDVSVVEEAASSAANTYKETSGRDVNVDVKGTLSDDIAGGVKLVSGSGRITLDNTLDERLRLLEDRMLPEIRKDLFGPNENRKFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V884</accession>
    <name>A0ABQ8V884_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_582822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="185" mass="20690" checksum="8F0BCDAC735131B2" modified="2025-10-08" version="1">MLYSTCSTSKSLRVLIFVLLLPVVCIIAVPHGPLVNIGNESTVNTRDLIHQRSPLVSKAIIHFHTSPGSRTTRNKDTARRAVVHSAVQRFLDKASPGLYGTENMSIQVKSWGKKNINVEGNEHCFVLQIELRPPGAIKRMITYQGWVSWTNREVSGYLKTDDDAETIVVEIQKNVLVPSDQREQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8M1</accession>
    <name>A0ABQ8V8M1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Interferon-inducible GTPase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_495398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030385">
        <property type="entry name" value="G_IRG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007743">
        <property type="entry name" value="Immunity-related_GTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051515">
        <property type="entry name" value="IRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32341">
        <property type="entry name" value="INTERFERON-INDUCIBLE GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32341:SF10">
        <property type="entry name" value="INTERFERON-INDUCIBLE GTPASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05049">
        <property type="entry name" value="IIGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51716">
        <property type="entry name" value="G_IRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IRG-type G" evidence="6">
        <location>
            <begin position="250"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="479"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4480336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="507" mass="58088" checksum="77E753004CB8EFA4" modified="2025-10-08" version="1">MGSSQSKSAKAAVDEINERKIRQNPIVLRMEKKHQEELESLQKDAEKRAEADEKLRSRQEKQHQKNVVLLQSQLDQEAEARRAAEDLHREAEQKRIKAEQEASDYAKQAEKAQKARDDAVSAAEKARTAMEEAEARAKSEHRARDEAEVERKNAVLSAEEFRDRERSARDAAAKAEEAKEKFQRLEEKARLTSEETEDELQKFKVEREKTEKELARAHRREAQLADLQPVHEPTRAEHEQTKNDRQYIEGRLHLAIAGMAGSGKSSLINAFRGVSKGTASAAATGVVETTRTIGRYEDPHPDRSKFVWYDIPGAGTANVGHTNYFIKQGLYIFDAIIVLFDSRFVDADITILENCKKFNIPAFIVRSKSDEHIKAIADEMREELDEDESEDEDDIRSKDREARRTRIDADAKEEYISVTRQNVRENLQRAGLDEEQRIYLISRRTLLRIVRGKQVAQTKLIDEYELIKDVMAAIKERRIDPPPPFKADPAKSGSYLNPFSWGGWGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9R8</accession>
    <name>A0ABQ8V9R8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_924178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="523" mass="57462" checksum="9ABEA392F8F97E8F" modified="2025-10-08" version="1">MSMSLIVGNQVASAAYDSSIYYSSISHSFLWDQCGNPCTSGTFQSLVTISTPYFAYSIPVDFFVFDDSRGFHTILGVQFWQSCDRLRCTDFISTLPLIQSNSSQPLPLYPSHAPLGPVTRPGVSGRDTLLAPSGEGLVRHSMESVYLTTQPTPIYAASSSGPIAAPLPGSNTIGSVCTPTSNDIFMSASSSMLPVDLNTRPSSLHLLRASLLRHLVTGVRCSAFAQDIIVLNRYAALHGLDLHGLVDVRSSQQAIIHHILAGQCFATKDIASAGHIHACEMFVADFDSKIEYFEAIADLLQSSKAVDLPVEKLKLMLESVCETDRYQPRDTHRQMLRGVQKYLTHVQAGSVAKEDMLPDSAPDIISGLDRFPLPVLLLYCRQHGVDICIATATVPHIREQLGRHLVKGLCYANHDLPGCRTVVNSFTLGSRTPVESYSQSDGFKSLLLRLLGHKLKSRPLKLTLDILKIPYLKSETKKQLQARLQLYVDNISSLDRSVAANIKMDQIRKEWPTLVPTSVTALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9X8</accession>
    <name>A0ABQ8V9X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4483130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="119" mass="13015" checksum="D7B06E9AF527E8A2" modified="2025-10-08" version="1">MTISESSPREPTTPGVYILRSSYALYLFTLRPIQSYVDGPPWTLQEPLQGSHLLALATTRSFPSSVAVSVAPFELRPAPSTLPHKLIIPKTYPKTYSDPGLTAGDHDDQDPPVDPDDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAZ5</accession>
    <name>A0ABQ8VAZ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_921529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20513">
        <property type="entry name" value="CYCLIN_CCNC_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="47"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="195"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4484609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="585" mass="64207" checksum="383600FCA299A03F" modified="2025-10-08" version="1">MATDFWASSHYKRWIVDRATLKQARADDLVYVSEPECLEFLAIYFANIISKLGKKLGFRQRVIATATVFFRRFYLKNSYCETDPYLVLSACCYVAAKAEESPVHIKNVVAESRALFSQEQYNVKHFPSDNSKLAEMEFYLVDDLECDLIVFHPYRTLLALCNKDFGNSNSSSDSPAEEAEAGELGTGIGADDGPRYWGTGQGQLELSEGGLQTAWFIINDTYRSELCLIYPPHLIAVTAIYLTLVLHTPTQNSIAHLLPYSPAFNSDSSNSGESSQTTPHPRRSSRTSDSSSKHANQQDPIDFLANLNVSLSAIATIAQEIISMYSLWNRYREDVTAEEMRNMNANANMGKRNTAGNFKSAMKGARVSQSMQSQKNLPRNVSASAATTSDMEWQLERQRFHGAMQLQAHLKKQGYASAPLPPQHMINGPYFMPQHPQQMQHRYPPALVPVSLGSLSPTKRSATGLRSRSGSRAGTPNSVGGGGRMEDLFGDGTSSGSPASHTSHAAGVGPRAGSTPLGNTPGSVGGADDTANSPINPWPFGQGRIVTAIFLSSMLNTMREARMNDMAHPSSGRPVVVNRMLERTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBJ0</accession>
    <name>A0ABQ8VBJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_774071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25821" checksum="066D7FDE4160D3DE" modified="2025-10-08" version="1" fragment="single">HRHLAFEMLYNAVVGPTSINNVFFVSFLQGFRMRCIDGTADLFDIVRSFNGGVENFVQSAETSIIKGFEDLNLLFIVDLEATTLRELTDACTNAGAPFEGKTFKEIFRDYLEDSGTPCPHLFETIKDRLSRQINLDEITSSTFRMKLLCWSVSGAPRIMHEGDPLKIQLVEDNDPFYLPSRIGQELQNAYLSLGTCAFKTCTQCKDARTAVHHWLLVEMLDAIGSYTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBM9</accession>
    <name>A0ABQ8VBM9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="1">
        <location>
            <begin position="217"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4485172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="364" mass="40619" checksum="B788F827D9D685F7" modified="2025-10-08" version="1">MELPTIDLDLFLSQSLETSAVQHECKKVADALITFGALILHDSRVTEGKNSAFLDLLEDYFAQSTSDIQKDERPELSYQVGVTLENTEKPKCAVDESCLSIIQRLEPSERPLDISAHSPDPKCRFFWKMSEVSPYETQFPGLNAPNVVPQAEEINARWTQTMEDWGESMKQAVENLADMACIGLGLPPCTFRDAGRYGPHLLAPTASDLEKYGRKDTILAGFHTDLNFLTIHGRSRYPGLNIWARNTGKRLPVKIPAGNYLLVQAGKQLEHLTGGLIKAGYHEVVVNDQTLKVIEKRKVENPERPLVRISSTFFWHLSSDFDLSPIPSLAERAKAFGASHIALGGYATDEPEYQPMKVGHQVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBQ7</accession>
    <name>A0ABQ8VBQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_837689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046379749" evidence="1">
        <location>
            <begin position="27"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="224" mass="25409" checksum="DA2CD15C2E49EF40" modified="2025-10-08" version="1">MTVLPQFLAYFFSVVLLFSSLPGVMTIPLTLPNTGDQVQQLEQRTHDNPMKIYAKRVFKRKNGYTSRGIVLNTLDPQEEILLVFGTSSGLDLHQDDDGKWKMEKINVRSDAGCVVLGLFRSERFDAEQSILGFGKSWQDAKIYQDLEVSAAHNRLEALNAVVKRLRNLDVARFEEIENHDGSTNVWDGLYLAMTDPASYKQKVDLSENKEGLIWNVEKLLAKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDC2</accession>
    <name>A0ABQ8VDC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14013" checksum="DC2957AB90ED1BE5" modified="2025-10-08" version="1">MTDSEESESEVTSHLLDDFGNASNQFLESDSAPVASGSHHVPNTTSNNRTGKNQHRESARIGDKKVYTALLEYHRRNITNKDTISQLLKTDYGINLSASSVTQHKRHRGIKGSRATTQSIGNLLCCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDT5</accession>
    <name>A0ABQ8VDT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HSF-type DNA-binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_398871</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="7">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="454" mass="49319" checksum="CBF026AA31F17FBD" modified="2025-10-08" version="1">MDSPYDEHPPHSLPPAHLSHLSRNLSGLSMNPGSSATNATHPHHPDRPFGLRISTSISNPGSHNPSPNAPPSRKRSFTSNPPSLPSLSTTVMVGAGMVSGSATPLLEEDISVRGMDLDLDYDKYDKYHEPKYEKYDPDLPPNSGLTSAPPSALPISASGSRGSITPSGGTSPIEGGGSGSGEEGTVSSTMGHSRMGSVHGSGMLTGMGSMGKPMPTNNFVTKLYQMINDPKSAHFIAWTEHGTSFVVSNVGEFSRSILGSHFKHNNFSSFVRQLNMYGFHKINRTPRAQRTSSDAQTWEFSHHKFLRGRPDLLDEIKRKALLEGQGGISVGPESVRARVELPGEVASQLGSMREEYRRVWEVLMAERRKNERLTGLLRSLWDVVGKGFPGSIHSSALVLLLTLTCTVRWAVLGQVMVLLVPTSTSPRQQPLLDLGIKRRYLHSDIHIAKAIITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE22</accession>
    <name>A0ABQ8VE22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VIT-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_867728</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="84"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="365"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4489853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="970" mass="104467" checksum="860022F30B3320AB" modified="2025-10-08" version="1">MTRCETRPPPPCAIPKPPPPCPPVALPPRPPTTNPPVTSPPVARPPVARPPVTGPPSGNPPGARPPVTNPPAANPPGSANPPGSRPPTTSPPSSNLPLVLRECNIKVWIVDVHSWVTLSQQFQNPSSSVAAHVTYTFSMLAGAAIYGFQIVRQDGTKVDGVVKQKDDAQKEMDIAVSEGLTAALGQEVTKDVFSIGIGNVAGNETITINLSYMSPLIDDEDRNQLRFTLPRSYMERYGRRPAGVKNSRLNHENVPFTMDVLIQQRGTIRSVSSPSGYNFTFGLGRPPNISPSPGISDSNIATATIRRSATSSARARDVMLIITADRLDNPRAFIETHPSPNHTTAAIGLTLVPHFGNSNYCPEMEYIVLVDRSGSMRGVKMEMTRQALIVLLQGLPSRGSFFNIFSYGTKATSLWPRSRAYDQATVNEARRHLDSMQADYGGTEIPNALDAVFASLPSRLTRPVSIFLLTDGGVWGSLLIQCVTRIESTIASKSSDKSFLRVYTIGIGDGVSTETCDRIARAGGGTSTYIVSDNEQYIGKCTRLVRAARTPPIVDIEVTWVTPKANASHDATGQVISLFDPEVPYDDEECGGVGPLAPILQAPDPVPSFYRSTRTQVYAIVPDSIAVTKEVKITGRIPVTGASVALTIPVQRFSPFAPFPASPGGIGTGTAFMHTLAAKALIQDREDWEDSGSAPVGKPSASSLKEDITRLGIDYKLTSRYTSLIAVDRRNRDVLGMGFYSAPGAKKPKKNIVAEAIRDQRVVIQARSLVHATFSSTPGGTGRAGVDTTTEALIILARLQNFDGSFDESSSKSDIERFYAELGVELRTGTETETEMKSIVDKFVSHTESERAQVVYITLLAWAYMAVQSKSKNAKAGEAFYDVKDKADVWLKENLKGSGTAGSDVDVDELKRQFLDKVVSLGHGGEIYGHGEFDEYVDSDEDDFDFDLGLDSGEEGDLALGGEGVGLVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VER5</accession>
    <name>A0ABQ8VER5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_834168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="330" mass="37325" checksum="E67E7558EBFB2841" modified="2025-10-08" version="1">MSDEESEYLSLYESNLTPLRVCLVALTWGLHDYFVTLEDEVHHVWPQRFNFAKFMFLWIRYYTLALLMFDVIQIHVFAVPGVTSDNLCVAMDSIIRVVGAISLWSVEIIMQLRIYALFNCSKRIAITNCILFLASIAGFLWILVYNAQRRRAVIASAISLPLPGCPSIHSGIEWAQWVPATIYEGILFGYALYKTIKSHAIRLRNGIHISLHSLLLRDNLVYFFGIACILVFNNLMVVGVTHIPWFSYGPFHAAVGILTTRMFLNVRKAANRTSFASGAERNVPEVISDSPFPDNVASWIVAQNSQLPSSLDRPHQDCIAMEHRGVTNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VET8</accession>
    <name>A0ABQ8VET8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Glutathione reductase</fullName>
            <ecNumber evidence="3 12">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_765724</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="3 12"/>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="13"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="366"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4491783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="485" mass="53031" checksum="20F563F60AE0BF56" modified="2025-10-08" version="1">MPPIFNKPTTDKYDLVIIGGGSGGSGFSRRAASYGKKVAVVEMTAHLGGTCVNVGCVPKKANCIYQIMWHAADLREKLMYHASGYKMQGLPEIPKFDWASFKPQRDAYIRKLNGIYHNNFDKEGVEYHRGYGRLKTPKSVEVTLADGQKYTLEADNICIATGGYPTIPSEKEIPGASLGITSDGFFDLEEQPKRVAVVGAGYIAVELAGVFNALGSETHLIIRGETVLRTFDPTLQQVLTPWMEHTGVKIQKSSKVVKVEGEKGKTLTVTLDSGKNIEVDCVLWAIGRHAATQDMGLEKHAVKLDEKGNVVVDEYQNSSVKGITAIGDVQGKALLTPVAIAAGRRLANRLFGPENFKDDKLSYENIPTVVFSHPTIGTVGLTEPQARQKYGDDQIKIYKSSFRALYFSMIEEEHKEPSTYKVICVGPEEKVVGIHIIGMGSDEAMQGFGIAVKMGARKQDLDDTVAIHPTSAEGLFSIPLRVYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEW3</accession>
    <name>A0ABQ8VEW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vps5 C terminal like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_369013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sorting nexin/Vps5-like C-terminal" evidence="1">
        <location>
            <begin position="40"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="161" mass="17878" checksum="7BCACAFA2314E871" modified="2025-10-08" version="1">MSPVSFTKRDPDLKLFLESDTFALDIKHRKIDPGSPGPSSDDYFDSKRTYLDSLEAQLHSLVKSIDLVSKHRMEMAQAVSEFGDHVKELAEGGDFNTGLNVSGSSQAQQLSQTLMGLAEVERKAQDLHVLQSEQDMITVLGTVDEYARLIGSVRMAFSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEX3</accession>
    <name>A0ABQ8VEX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_921188</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14879">
        <property type="entry name" value="MYSc_Myo17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036037">
        <property type="entry name" value="MYSc_Myo17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF45">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 14" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8 14" id="KW-0518">Myosin</keyword>
    <keyword evidence="14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="915"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="954"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1218"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1613"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1640"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1672"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="17">
        <location>
            <begin position="13"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="18">
        <location>
            <begin position="1856"/>
            <end position="1911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="14">
        <location>
            <begin position="642"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="767"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="767"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="113"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4486798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1915" mass="215086" checksum="4EC817F26768E4D4" modified="2025-10-08" version="1">MNRQSTIHHQRLEAVTDLSQLNGISDDVIVACIRERFMADNIYTNVGTSALVALNPHKYVSSNADNVLQKYASEYRNTTSPKELLPPHIFQLANNVYYHMKRTTQDQSILLSGETASGKSESRRLAIKAILELSVSNPGKKGAKLASQVPAAEFVLESFGNARTLFNPNASRFGKYTELQFSERGRLTGVKTLEYYLERNRVAGAPSGERNFHIFYYLVAGATPEERQHLHLIDKTAYRYLGQRNVTARSNGAKDDDAVRFEQLKVALKTIGLSKRHVAQTCQLLAAILHLGNLEFVIDRSRNEDAAVVRNTDVCAIVADFLGVPPGELEQSLSYRSKMVKKEMCTIFLDPDGASDNRDDLAKALYSLLFSWLNEHINQRLCKDDFSTFIGLFDLPGPQNMTSRPNSLDQFCINFANEKLQHWTQKRLFEAHVNEYAAEGIARFVPSIAYFDNTECIRLLQNKPGGLVHIMDDQARRQPKKTNHTMVEAFQKRWGNHSSFKTGNIDRSGFPTFTVSHYNGAVTYSSENFIERNQDELNSDFVNLLRGIEGMEGTGSINPFVKGLFSGKQIATTAHPRNEDTIVAAQQNMKPMRAPSTRRKGTIKRMSTVKEGVEATDDDDGVGNIGSSNGTACVAGEFRVALDTLFETLDDTQSWHVFCINPNDSQLPNQLEGRSVKGQVRSLGLTEIAKRCVNVFEVNMMPEEFCDRYKEGLQEAGVVGGDERDKVEYAKSALGLNENDIVLGQHKVFLSQAAFHLLEDHLRSRDVEEQKRNRLRDAEAEAGLEPRGAGDPYAPYSYPNADGEAAWSAGHNENYGSSNQHLPLVANASPFQRADLYDDGDDRSLHSEDFDARSKFTSQRDDSISNFGSESYAPSRNMFQNTDKAALANKEALPGEIQEGETTEVIKESSARRRWVALCWLLTWWVPSPLLLWIGRMKREDVRQAWREKLALNLIIWFCCGVSIFIIAVLGLVICPTQHVFNTGELSSHDSTAKEVYTSIRGEVFDLGIISDNHQRIVSVVPTKSILKYGGTTSDNIFPVQISALCNGVTGTVSPFVALDTTNNSDINAQYHDFRINTNDSRPDWYFESMVTMRYTSRVGFLGYTKDEIKDMSTSGKSVGIYDGMIYDVTSYVSSQPSLIAPPGFQAPADTDKNFMDPSVIDIFKFNNGGDITKSLNALVPNTISSQVLERQKVCLRNLFLIGKVDNRNSPQCLFSKYILLALSLFMVSVIGFKFLASINFSAARAPEDHDKFVICQVPCYTEGDSSLRRTIDTLAQMKYDDKRKLLVVICDGMIVGSGNDRPTPRIVLDILGADPNLDPEPLSFLSLGEGAKQHNMGKIYSGLYECAGHVVPYMVIVKVGKPNERSRPGNRGKRDSQLILMHFLNKVHFNSPMNPMELEMYHQIKNVIGVNPTFYEYLFTVDADTTVDQYSINRLISAMIHDKKLLACCGETELSNAKQSILTMMQVYEYFISHHMAKAFESLFGSVTCLPGCFSLYRLRAPDTHKPLFIANQVVHDYSENRVDTLHMKNLLHLGEDRYLTTLLLKHFPTLKTQFVRDAHAYTVAPDDWKVLLSQRRRWINSTVHNLGELMFLEQLCGFCCFSMRFVVMIDLISTIIQPVTVGYIVYLIYSVVGAGEAIPTLSLIMIAAIYGLQALVFIMRLKWDMVGWMVFYVLAIPIFSLYLPLYSFWRMDDFSWGATRLVMGESGKKLIVHDEGKFDPKAIPLKSWTDYENELWDKESNHSIGSWVPPNKLHNEGYPESQTASLYGRETYYEPQRAFSPAPSQMMYPPPGYQSGRNTPQSNLRMPMDTGMMYGQPQFTPSLYQPTPSRPTTNYLDMPIPTTSSPDNGSFSGGPSNMDIERAVQDIIRVADLNSVTKRGIRRQLEEQYGIDLASRKATINAAIDKCLAEQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEZ7</accession>
    <name>A0ABQ8VEZ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_981350</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="12">
        <location>
            <begin position="27"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="11">
        <location>
            <begin position="178"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="14">
        <location>
            <begin position="286"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="13">
        <location>
            <begin position="451"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="124"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4491853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="615" mass="68788" checksum="8EAB1B8D4FF59224" modified="2025-10-08" version="1">MSYQLDTGICHRIQNATPNEGELFNGSHTLQVLSLKKVGKQTEGVNLPSDRYRIVLSDGVQFIQAMLATQLNEMVVDKHLTRFTIVCVERLSCNYVQEKRLVIIMALRILGQVDQKIGEPVSIDVSTSEASTPAPERPPHQSVVQPSTSSITAQSASRPPPKGNWHPIEGLSPYQNNWTIKARVTQKSELKHYSTQRGEGKLFNVTFMDETGEIRATAFNQVAESLYPKLEEGKVYYVSKGKVNLAKKKFSNVMNDFEISLEKNAEIEECFETTNLPMIKYSFVTLGELQNLNKDSTCDVIAILKEYSDVNEITSRATNRTMKKRELTLVDKSGFSVRLTLWGNQAENFKPDEPNPVVAFKGVKVGDFGGRSLGMIASSTMTQNPDIPESHALRGWFDSSGSGASFQSHSNAGGSFGAAGGGGFSRSELKPLLEMKLEANRIPESEEKPVYFSTRAMVMHIRGENIAYPACETCNKKVVEDGGAWRCDKCDKTLAGPTYRYIMSFAVSDHTGQLWFQGFNDVGDTVFEKTANEVIEIKDRDETQYNLLLAKACCKSYNFLLRAKRDSYNDNNRIRYGVSRILPLNYKEECDALLDLMDTPWGQQTLKSESDMVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF07</accession>
    <name>A0ABQ8VF07_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_765779</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="10">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4491872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="273" mass="29370" checksum="31E1DDB4AD427B57" modified="2025-10-08" version="1">MTTASVYSSPGFDFSNLTRNNFLSEKGLPLPKATSTGTTIVGCIFEDGIILGADTRATEGPIVADKNCEKIHYLTESIRCCGAGTAADTEFVTNLISSNMEMHALTHGRKPRVVTAMTMLKQYLFRYQGQVGAALVLGGVDSTGPNLFTIAPHGSTDKLPYVTMGSGSLAAMAVFESNWRANMSRADALQLVKDAISAGIFNDLGSGSNVDACIITANHTEMLRNVEMPNERVQKERTYVFPKGTTAWKKEDIKKLVLSEEVTPIGGEAMDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF99</accession>
    <name>A0ABQ8VF99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="20986" checksum="B5126B964847782E" modified="2025-10-08" version="1">MYAVEGDVGGCLEDNGVVFIEVEGGVVVGVEKVVEGVGEEGGEGVVTRERGGMRKRRRRRRRSGRGEGVGGKGGGGEVKEDEKIPRDVADVNFLIANLRRSPDTPIPPPPHPPTSHQHQPVIAAYSILSITSNFASLFGYHSSIRSPLSTISLRKYNNTKRNKNTKRGNKQTKERRQYNALDTNHKTITNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGB2</accession>
    <name>A0ABQ8VGB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_764324</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="44"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4493292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="494" mass="53422" checksum="6E32F526BFF6D3CE" modified="2025-10-08" version="1">MTVSCSDSDTSSLNETTPLLNDAQHDPEDQDPPIQKATPLPIAQLLIVCAIRLMDPIAFTQIFPYINEFIAFLKLTDDPSQTGFYSGLVESTFAVTQFLAIYQWSKLSNKIGRRPVIMVGTFGVALSTMYFGLSSSLTDLLLSRAIGGIFGGTVSVVQSVVGEITDASNQAAAFPIYGLVWPIGGITGPFIGGVLSNPAEKYGSIFQNSVFSRHPYFLPCLVAGIIALSGVLIGYIYLEETLRKKTRNGSQDSFIDDREPTLRELLSIPIIRALSISAFALNFNGTAFDVLFVLFCYTPIKDGGLAFSPSTIGFTLSSSGLISSAMQIFIMPVILKRIEASRIYNISIAAWPIVFAIIPILNVIARHGLVEETGNLDVWSNVKLWTGILFVLAISKVGGMAYSVSLILTKSNVSTPAVLAVSNGVMSCSMSLARIISPALASSVFALSVEYHLLGGYFWALMMVCFCLLACCLGRNISRLSKSSLTHHKPQNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGG4</accession>
    <name>A0ABQ8VGG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_327171</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4493339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="49308" checksum="0A599CBAC459C3B7" modified="2025-10-08" version="1">MPQTKIVLTLVDAEAIKEVMTSRARFPKPINLYQPLSIFGDNIVASEGEVWKRYRKIAAPAFSERNNNLIWEESLRIALDLFDNVWGSENSIVIDHVPKLTVPFALFVLSSAAFGKRISWSDSDTIPSNHRMSFKSALHEVSLNCFTKILVPKWAMWINEHTRKVNLAFEELELYMLDMISEHRNAEKKEVRHDLFSNLLDASDDDPTFTDGDLISNIFIFLIAGHETTAHTLCYAFAFLALYPEQQELLFTQVKSILPDGTIPMYHEMPLFTYTMAVINETLRMCPIVTGIPKYSAEDTTLTIGNISGDKLVLPMPRGTEIDINTMGLHYNPRYWQDPEEFRPARFLDPDWPRDAFVPFSAGPRACIGRKFFETEGVAVISMLISRYKIEIKEDPQFSNETFEERTARVLASKVGLTTTPIRVPLVFKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGN4</accession>
    <name>A0ABQ8VGN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="143" mass="15766" checksum="E584DA67EC56887F" modified="2025-10-08" version="1">MSPGSFEFPWPKRGRGGEEGKGVTRNRNVCLSIAGHPVLGKPGVYEQPMFVKGGYQQPPLPLNIICKDAPTAMRLYSVLLPVVERIYKLNPEKFDIKKFVNSNEFQEVACELDGDDCLKWAVKLGKYVGVFLSGYVSQLGGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGQ3</accession>
    <name>A0ABQ8VGQ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_831002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="224" mass="25300" checksum="964B106F90005EC6" modified="2025-10-08" version="1">MSQPSTPTSPSTPQAEIIQLCSRHFTSIPLSLSRFQRRWFLTFPRAYGLPDPDSQRIVCALNSPDYSATNQHARSHFWLNPSCRSQRYNPSDSTTKYSAVSPIHLLLDSDYPVARLTGRIRAEPSNDPHDGGKRIACYEVEVVTPDSGLLRQCYYCLSWEATGKADTRFSPSGNDIYWCCSCEAAGWVSSTIRKLRLQDILPWSNSEEDYKDNLYSPTRSMSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH01</accession>
    <name>A0ABQ8VH01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_832420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="273" mass="30761" checksum="DF97B0FCF1F0885F" modified="2025-10-08" version="1">MYVRALLNCKGTFKLQNRRNYLGRWIVPHTKTKNLVSPFHPFDCSTIIMHMVQLRLFPTLLLLSTVLGIAAAPPIRRGSSAADTILSRADTKDNSIQIIFRRSNFQPPDGRSKATEIIKHYASDAPWSTDQDWIIYLGTHGGYYAVPDSTAEHGFTNTKIPAQRSKQFGVKHRIIIGTVRSLDYKPDMLLASKSIFEIKPTGKADLIKQAMNYLRVRWELQQTDEEKNNWAEIQKKMKEAEDAATEEAARAVEATGPEGVAAAEALMSMKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHV1</accession>
    <name>A0ABQ8VHV1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_308170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="65576" checksum="499A93B072776733" modified="2025-10-08" version="1">MSSRFPSTQRRPMFNALSTLLSLRNGRQLDPPLGQTYLSFEDPELYNPSIGDHCSPTMEFSSAICQRPTHPISNSSSRSNALKERFLDRFAEVISNRKGVEYVTCTVMTEHEDWMVVYASRNDGFDEKDRIFCDKFSAEMSKLFVGEHTVDEPGASLWTLLLEYYLPRLNHYNKELLALALTIRALRQISSSINDKDLKELLDSFLNVVGHPSSTLKFHRLCRLALRLHATPLAQRLIQDNLGNNGSRLWRVIGFFARLQRAHRTFLEIAQILPTVKVVLISQSDEVKPSNCALLSLSSTLRLIHQPLDSATVKRYISRAYTVPDAQQMFNHRQSKSLHVHAELQIIRYLLQAHIPIDEIVQYMGCSKRSCFMCKTFLLIFSGLGTRGCHGKLYNQWSIPEIQGIEEDTKEKLERAVIRIQDILVQEIKKPLSPRNAVFESSAGTTAVSSSRASVTSGSPGSPSESPIEDSEDSDTREEIAHQENLYEWEATPVASHQCLPVLANSGGTHNLIAGTGTRWLHHMGIADNLLFRVSEPVTLSSLSLTQALGEIWIPNKFSPELDSTFPKSRKSLRDVLLKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIE4</accession>
    <name>A0ABQ8VIE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_830433</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="5">
        <location>
            <begin position="34"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="202" mass="22802" checksum="C94EEA744F7302D1" modified="2025-10-08" version="1">MLGRFRSLLFGPPFDPSSLRATMSSATNASTEIATFAAGCFWGVEHIFLKHFPPKENKGIIKTAVGYTGGKETVTNPGYRDVCSGETDHAEALRIEFDPTIVSYADLVEFFYRTHEPTTVNRQGNDRGTQYRSAIFANTPKQLETALAVTEEVQQKRFTPKGEKIVTQIIEAGPWYDAEDYHQLYLFKNPNGYQCATHRLHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ52</accession>
    <name>A0ABQ8VJ52_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_793409</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039772">
        <property type="entry name" value="Bin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010675">
        <property type="entry name" value="Bin3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024160">
        <property type="entry name" value="BIN3_SAM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315:SF0">
        <property type="entry name" value="7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315">
        <property type="entry name" value="BICOID-INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06859">
        <property type="entry name" value="Bin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51515">
        <property type="entry name" value="BIN3_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bin3-type SAM" evidence="7">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4496431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="274" mass="30758" checksum="D1CE03183727B18D" modified="2025-10-08" version="1">MSVPTHGNYHGYYLKRPSVTDPRLALLPENTFSGKRVLDIGCNAGWVTCEIAQSRGAHKVVGVDIDDTLIRAAWKRRQVVWSLQKPQSSQSNEDNDLMDFEDLTRNASMEVTHLQADYFPASLQHSFGPLPIPPSKIRGKHAFPHNVSFRTADWVTEEIVEDANGYDVVIAFSISKWIHINGGDGGLRAFFRRVYSVLEPGGVFILEPQEWDTYKKAKRLNESLRNSAQTLELRPSDFESILGDIGFSPACHLGTTGDGGFRRTVDLYVKRHVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJJ4</accession>
    <name>A0ABQ8VJJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">von Willebrand factor type A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_262213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="4"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="279"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4496566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1065" mass="113949" checksum="50F3E95487A7C2B1" modified="2025-10-08" version="1">MGLFYHCRLYDLHTGNNLLLDGCSAQVSITDVHAAVTISQKFTCSSNHGNSAHQVSGVYMFSLMRDAAVCKFEMVRGDGTKVEGVVKEKEEAKREYDEALRQGYTASLGQQETGDVFSISVGSIAAEETVTINLKYVQSLIDDEKKNQVKFIFPRTYAQRYGSAPTVNSAFGRTVQQPFTMNATVQQAGSINAISCPSGHPISLEFNHQNSRNNSIANVLLQDRSGFLSNDVVLVITATGLDAPRCFIEQHSSPNHETTALALTFVPRFNVPDVQGGVEYIFLVDRSGSMHGQNIQLVREALVVLLRGLPTNGTTFNIFSFGSEATKLWDQSRAYDQSSLEEATLHVDSMQADYGGTEIASALRLVYDSLPKSLIRPVAVFLLTDGGAWDVSTCIKYTQSARTTLPGPKTFIRVFSVGIGDGASSDTCESISRAGGGMTVYVKQGEPLTGKCSRLVRAARTPEVRVNVDWGLGEKEEQIDEPDDFEFVDKPTPESASPVNPPSATISLFDPDSDDMDVDPSINPILHPTGPPPKPNPTLPPPPRIQQSPLASQIPSIFPGSRTQIYAIVRTPKNNTVNSMTTEIKVRGVVTTTGDLVELVVPVSKVLSSPTVDALGFPFLHTLAAKALIKDREEGKHAFPPSASALFDSPNLNTELKETYLEKEIIRLGTEYHLASRYTSFLAVDRRSSGGQKLLNIVPTMLFGSASSSTTTGKTLFTGGGFGGFGSTGGPRKFGSANTRSRGYGSAAVAMPMTSNTVHSNVSFGMGLMGSSQGPIPYSITTGGGALFGSSSPPVFGGSTGPPPPTIATVPFGALPPPPPGRPPQSIFGHMARFGNVSSSTPLAPPAPAPASPNFSPSSPMANSSFFGSTADDSEGEDADGSVPNNISPKSSVNPFSSTISSSSDSYHILGTTAQQHQRTPGSLLAAVARLQQWHGGFKLTSTLLQLLGEALNVNILLLLGSDPNDNNILVKDFAKKLESQVGIEDPDVGATLFALVWMEKYNKASGSRVVDDSQDDNDETRDMREKAQEWVNSQLRLGADSGDEQTRRRLGELKGGVERMLGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK93</accession>
    <name>A0ABQ8VK93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_824961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18468" checksum="8D00BA9F12DC6D14" modified="2025-10-08" version="1">MPDFINLASETEHNSRGVGEVKTFWSYPTATYNTIFLGNMVDDDGNFVSWRVGKGLVPKMIKQIWGEVVMFNSRFGFWTNGHIVFLFVRTSPHDLTFSHARLWTDPHVFLGLVGLSMACVHASLCPNQQAEQALVDHLCPPQIRRCRNSPPRSALHPGQPHPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKA7</accession>
    <name>A0ABQ8VKA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_880479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="1">
        <location>
            <begin position="11"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="24390" checksum="81BF56C08D7CECE6" modified="2025-10-08" version="1">MLRIGPYSAWVVVDGAGLETHCVESSHHNRTTSTSGWISSEAGKKFSVYWSNAVRDVDLEATVFIDGVECNRHVMLAASDFPHRPDTVRVSYTRTSDFTRRDFFFSVVQVIDDNEYLPSVDYNKFGVITVELWRLRVNRVVRQQLQYDPSKIPMLEFQVLPEQTKKGGTHHVRFGKEYSASRPIVDMVDGQKLDKAPYMSFSFKYRPRGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKQ5</accession>
    <name>A0ABQ8VKQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal L28e/Mak16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_829697</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="15664" checksum="4C6E971B2DC45E42" modified="2025-10-08" version="1">MSSDLQWLLLRKSNSYMVKGLPEGPIFSKEPGNLLNIHSHKYSGLANAKTIDVSDVNGKITITTYKTKVSPRAVAPARSTFSVRSRSGTRRALGIASSTAKRGYRPDLRKATLARTAALLSAQKEPKGAPPKKLRGKKATKGFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKV8</accession>
    <name>A0ABQ8VKV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_824314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="118" mass="13629" checksum="59448FEA74662234" modified="2025-10-08" version="1">MEQPMIIDLHKATGELTLGDEQIKTMSTTVKAAIHSYMQDYQPGMNELARNAISREPWTPNVTVTEETLNRIRNLNIPRSCYPYSHLPDMLSHRLGRFQNDTQLKQRMEALFGSKTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL60</accession>
    <name>A0ABQ8VL60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_823325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="100" mass="11624" checksum="7009E159FFA70433" modified="2025-10-08" version="1">MNLYMDAKNMIYFALSLSGACWEELCYDPTVIIRRVQGKNGIDPRYIFIIDGKQYITTEAITVRKTKFLLGCATHRFKVQQVLNDELSKLIFRRLTPSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL72</accession>
    <name>A0ABQ8VL72_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ribonuclease H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_829189</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="275"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4494481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="674" mass="73847" checksum="CA58A06F9453399E" modified="2025-10-08" version="1">MKRSTASISSSPTTQKTKKAKLSPEYSEDETNIATDKVEGGGWTKVEKRKKKKAHKVELKLDTTQPKFMYSNRDILQRQRAIGIEEVRDLALHIIADAPPPNWLRIENAQLIPKVVVILVPGLTPDVLGIPPPPTSALRNPNLPISIPLPPRQDPLNLTPTGVSFIGSTFSHACPTRAPGDQTKMHSVLSTFFNLPISGAEKKRRLEVKAKVKTSEYGSSDPSEYILTVEQMIENEYPIPSYLADVDNERPPGWVETPAETKLGDQDRNPRPRRKVYGIDCEMCTTEDGKELTRVCMIDYDTQLVVYDQLVIPNKPVVDYLTRWSGITAESLATATTTFEEAQANVLKLLSPVSSHIPKANPFSTKPSVASSSAPLLTPILLGHSLESDLKALKIAHSFCVDTALIYSHPRGRPFKPGLAWLTKKWCGREIQTRGEGGHDPEEDARATMDLVRKKVENGHEFGEFKADLEGLFERMGRAVKRSSTSTVSTGTGGEKIRTAVVDHGNPGVMHGNKASTSIGCKDDDEVVKNAVELVGSHDFVFVRLMGLAGVRGWITPRVNVSDSTPALIPAADPPASPTSEAFSSALLATSAHLQTIHSSLPPRTALLIFTGHSDPRKMSELNKRKAAFEAAIRKGVSTDQLSENERWSAADMRELEEAVEVAKRGFLFLGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLN1</accession>
    <name>A0ABQ8VLN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_223253</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="142"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="293" mass="32849" checksum="8A9B7458EEDE937B" modified="2025-10-08" version="1">MMAHRFGNWAVQRCLEAAFTPEERKKIASCMRGRIVELATNCYGCHVLQKALDCEEDIRLLIVSELLLGDPAQTLVNKHASHVWSKIMELTWTPPAPPIFTYVNKSLKGKWAALACHETGSLVVQHAFENLEDSAKDGIIDELLNQGLSVFSEVAKNQWGSYCVQHILEHGSDMHRQLTLDHLIAGLLEYSTNEQGYKSITKALKEGGKETLDRVVKRMCEPAKSSSRRAMVVDLALSVTGSQLIASVLPSADREQRALLYDCIRGHIVTLRGCKTGSKVIWLFDRMRAYYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLU6</accession>
    <name>A0ABQ8VLU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_894699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="384" mass="43539" checksum="0273BEF60F7FCD5B" modified="2025-10-08" version="1">MTFDISTNNSYSGLFKVITEEQHLDPADILDNLEESHDQVEVDLSGLSNAVREVSKSVSEKTSQEYLRCDEINLNGSPIATNVECSTYAHAQKMRAAATFGFGQIHGLGMQAWHQSEISGKMLGNASVSETVSSYMLSLRCRKTRAGETATSARAVTSQLLECLYHFNWQQSSAFFFSSQKAPKGHLGAHAHFLLNLGYNLAFCGLLRVDELLKIQMQDISVSPNPQTGQTKLMLCLPFRKTNIKPFVWDEMPEEYQHICVVRAFSRWVLLSGLTEGYLFCKIRAGDCIAEENEPMTSEQFLELFRNNLLDIGMDFWLSVERRWPLRQICEWGGGWSQEFTHLTIVKYLISWNDNPHVDRDDFFNMHWAPTTVCPTCNCSCHCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMJ0</accession>
    <name>A0ABQ8VMJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_759310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="26"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="217" mass="23722" checksum="99F6F7A7F3676E41" modified="2025-10-08" version="1">MPYPGGPINSNVPVVYTEDAATKLSDRVRRRCFNCCTTDTSTWRRSNLSPGKVLCNKCGLFERTHSRPRPEQFPHKRGPLAASTLRSRSPPVPHSLPSPSMHNQSTGHGSHPQGSPPMSSHNTLPPISPPYSYSHPPHPSLAPLSSVAPTSIGNHHELKREEDHKKSLSRPWQDRGSPPISKRSPPSGRASPVPPPMSSVSTASVKSSRSRYGRDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VML8</accession>
    <name>A0ABQ8VML8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporter NIPA-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_267503</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF85">
        <property type="entry name" value="DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G15880)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="412"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="484" mass="52871" checksum="FC6478B58922EBC9" modified="2025-10-08" version="1">MTVDDKWIGLALAVSSSMAIGMSSIITKKGLNAAAGEGTYGAAASDNLSYLKNGVWQVGRNFDFNIGRRYLLILSGWSCSITLHNQIRLIRLNTCNTCPPMNILYRSITESSFLVANFAAYTFAPPILVTPLGALSVLIGAVLASFLLNEELGHLGRVGCGLSLIGSLIIVLHAPEDKEVETVDEILGYAVQPGFLLYVFTVLVFSMVMIYVVAPRHGKSNPLVFISICSVVGSVSVMSIKGFGIAVKLTFGGKNQFTRPSTYLFAIVSTFCILVQMNYFNKALDAFSVNIVNPMYYVGFSTATIVASLILFQGFNTTDTTNTVSLLCGFVVIFLGVHILNLSRRSNDEAHLSTDAGVLDRPLNFTGRLSLDGWHGIVEGGRPEGGSHRMTHGRQSSLYRSQTSTLFNAFEGEEDTSRHEHVGLHQLREEDESDDDDANELTRLRSVPERQVDPRRSASRSHSNSPQPPNHRSLADLRPSPRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMS8</accession>
    <name>A0ABQ8VMS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_902484</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="62"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="166"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="448"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="504"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="695" mass="76593" checksum="47D0460951996167" modified="2025-10-08" version="1">MSSQHSQHDDESVIESQSVKQTQPSSQGLDFGREIHENVWGSFYPLVKDMKEVNLFKPKLTYRIGRSLHNDVVFPGYKISNKHAEITWDGRETKDSIIMLRDNSSNGTYVNGQRLGKGVSRILPDGAEVAFGSPGPSSTQPAEDYRFIFRHTASGQQREDGFYGLYDSHDQLGRGTFASVVRCLERKTGILWAAKMFSNLLTGGGSSSLGSRSNEKMVSREIGILQTLSHPNICFLKETFITEERKLILVLELIEGGDLLEYILSSSGVSEEITQHITYQLCLALSYVHSRGIAHRDLKPENILLTKSNPPDVKVADFGLAKAIDSQTMLKTMCGTPAYLAPEIVTQTNMEGYDNLVDSWSVGAIVFSMLTNASPFIEDENQPDIRVRISTRTVDWRILREKTSNPMIIDFIERLLNPDPAVRMTLADALDHLWLQDYVKKNNRDAIADRNLGKQRDQQPESSESIPTGRDATPNNPNEEKQPGSTFFSQGFQKLAINDKKQVGPSNTNDRAGVSSNSASADHPNGAADDDSEMDDATPPPPPPSQTRKLQSQNSRVLRRRKDVLEDANAGEMTIPRPSPELLSQFDEKRKREEDVGKPATGPSHTPEKRRGKRAHGDLSAVPEMADNGSGSGGRIAAMSAENGSADDSGAQPTPSKRRRNAPPSNNATRGKKVKKPTEPAVGVRRSSRNKSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN67</accession>
    <name>A0ABQ8VN67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_760001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="283" mass="32230" checksum="3A21B289B4F76252" modified="2025-10-08" version="1">MTQDERYNKFCDCLIEIAQVVPTNHTAGHLNALQIHVLNNLDRNCPFRELATSRLKVQQADGLFDHHQINTREGIFSGLIFRGILFNTPTLRELDNGGFFDSWEAWKQFVLHHEQKGDDYLCNKSAFGRTNGRSHHNAHRFWIASAKLHAKLQEPSITFTQIIDYIANTKGDDSKSLFVTFGVLSAYLFAVDLVYAGCIPHPSLQEIAAIIPKLDKGALHGLLNLGFASSSSEVEIVPAFITLFHRLDCDQKLLPIKKQIGFDFFMLEHSLCKLSRDQWLERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNK9</accession>
    <name>A0ABQ8VNK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_758535</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF189">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="84"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="594"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="594"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="649" mass="69798" checksum="FF41114D06399780" modified="2025-10-08" version="1">MAPPGSSSPSTEFDHNKASSTTSPSESIEDIQTIHSTASRSVPKLSDEPNVQKKEYLHSLEEETSNIQLTDQTNLLPFRQIIIVYIALSSCVVVTALDSVIVATSLSTIANSFRAGSVISWVPSAYLLTSTAFQPLYGRFSDIFGRKSAMCLAMGLYMLGNLISGFTKGSIVQVIICRGVAGAGGGGIVGMMQIIVSDIITLRERGKYHGMIGAVVALGYTIGPIVGGLLAQKVSWRWCFWVTLPLSLVSSAVVVLVLPVKPVAGDIRKKLLLIDYVGSLLTLIGCALIMLPLIWGGVTFPWTHPVTLSLLSSGALVVLLFCLYEWKCAKLPIVPMYIFKHSTVSGVYICMFANGFVFFSSLYYIPQFFQAGLGYSPIRAGLFLIPLLVGQTAFSWVAGMLVSYTGRYRASCDFRGTTHRANARNLFQTIVYTGFAFIAISCGFISTITHNTSKATMVVLMLLVGCGSGLTLATTTVAVQASVERKDMSVVTAFRNFVRSLGAAFSLSVASSVVNNSLLASMIEISLSPSTITTILNDPSILARASSIGLPDEQALHVLEHGYEAGFKKFFIINASLGVMATIVSATMVKHKELSRDDDEKLKSEAKAGLKKQEENQDPEAGVQSSELVVKRDAEMGVADVRMVSRGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP86</accession>
    <name>A0ABQ8VP86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_758022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07992">
        <property type="entry name" value="LPLAT_AAK14816-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="526" mass="60279" checksum="C5C6EA6D6B65441F" modified="2025-10-08" version="1">MTKGTPTPWPYTLIRLLFQFTLKVFYGTIVVSNAHFIPETGKPCIVCANHSNSLTDALLLVTSVPSNRRNMLRLTAKSTQFGKKTFTSWLIESAGTVPIHRRKDFDGPVDNSQAMTSLIKALEDGDAVMMFPEGMSRFHPTIAPLKTGVARLASDVLSRHRDDPDFEINILNCSITYMHRQHWRSDVLVTWHPPIILRPKDNPELLEPAEPETIRAVTKQIYTQISSGTFDSPSWHLVQSSKLAARMYAPLGTRMSLGDHVRITRTFLEAFKDAHEDGSEDNQPIHPDIVKVAQLQEDLKAYQHRLISYGIKDDRVRRPLSRREILRRMAIRLFWSCFLFSISIPGLLLWFPVILTTFYAVHEFKKSGPVFDTFDEIAQYKLVYGLVSGICVWLGGVILTLPFAMITVFLIPALMWMTLRWMEDCVASTRAFFTLFRLLRVGKQTLNEMRSLHDVLHRQIMDLAIALGLPSDPEEFFPQAGGKEKGRVMGSWQSKAGYFSIRRRRKRDWNETLRLYDKVDYPDEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPB2</accession>
    <name>A0ABQ8VPB2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VanZ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_894289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30601" checksum="3E6AA344F22BD601" modified="2025-10-08" version="1">MLPSAMAEKRKLIHRLTKTIMKSHRMRLPNHHNLPIRLRPWFIVFTVIIMLCLMFLGFTNFSHSLPLNDKFLHFICFLIATTVFYFIFDVDEEYRRIWFWRHSGLILTGFICFFCGGILSEVVQSLLPFKEFQMGDVIANLLGSAIGLYAAYHTERYYRHRREISRLYRPLDMDALSDEDDDEASGTQLLPTHNHPQQRSKGSSTTSKSVRLADVWDEREELFGIGEDSDGDEEEGDLNGSSPSNTRITSQTHPPLPKVVVTASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPZ8</accession>
    <name>A0ABQ8VPZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="58296" checksum="BC8DD6C311FCA588" modified="2025-10-08" version="1">MANARLKRARQSREERASSRYGPAASEEPLAPTFTARSRGKKTTVLPGDDANAAELLMNLSHPPKSNEVLEREREERLQSWIDREIDRHTQPKTVTKGVCAVVLSISASDIQSKAAPSLSNISLSEASDLSEGLDATPAPMNLSQKKSLLKRKAAVLIGSDSEDKDLDSDPGTFDIKYEITLGKKARVDCVLDNNTTFSVFRQRIASEMGIPLQQLSALGYIASFWPRSPKPVPKLVDTDARYEDMVGILEEYMKVEYTKHGKPKKKKAFSVILIDTGSESDGKKSSKAKSHDNEGPALENNADEQEVLIIRQIVKNFSCAEHPKKACYVTTNGLHYAFTAGDLSIWAGLVRKHEAVLKTPPEVILQGIGEKAVKQGKYGVGQASTAYGAPPHWGYSYPPPPPLGYYTTPAYPGHYSNIPAPNPGSVAFSSPPSSPQKPAEFPHVNDWLAKLDSDEYRGRDNHNYIQFTTIFAHEELTHLDDLHLIGSADKLRTLLACNLGNANRLWKYIVDDMDSITGGGRSSKKRQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ96</accession>
    <name>A0ABQ8VQ96_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_139252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="58964" checksum="3149FE2EF3DB404D" modified="2025-10-08" version="1">MCPLDPLREAASADESSEIRSSHSLLVLESARDGHKVSLPSHSPICRLPVELLIRIFHEVLPEPMSVPFGCAQLWYLGHICIRWRLIISSEMPLLWSTIELNFRLSARAARLSRHSTEIIRICLERTRDCLLTIAFTCPSDVGATTRDDWLRCLDTLVGVSNRWKTIDLFIPITVLSRLVPAKGRLDSLQTLSLSLEPQNARSLPHAIDVFEDAPKLTSVTMSSHLSLDSFRLPWNQLAIYRTQRMEVRNCIEILRLTPNLHALHAKLERPRGNILGEYASSDSGQLGALLPISHQSLQSLSINVLMRPEHEHELFQDLLPVPSNPDRSKQSQIVFPSLFNFRLATGPGSLANFAALSLAGSCFGPSLTKVTIRSVFDAPADYLGARDFLLGLPMVRQLAFGVCFHHNQDVVNILYEILSPPSPSSSGSIGEVVLPKLEVLVLDINYDDSQGLFMPSWVMDPMKEMIRSRRRCDFARPYGCVPLQKFHLYLASWNTPRQPFSKGLEELREEGFEIRVLRGLAAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQC8</accession>
    <name>A0ABQ8VQC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_864689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="192" mass="20599" checksum="15CDB76771D115A9" modified="2025-10-08" version="1">MMIMNVPKSFLLGFILLATNGITLVNAAAWVAGFQSTGFVGWNLRQYTHLFEGNPREVASLIGADQNSLPGVVCGTWTEFKIIGNSNPGIYEFNCVPTPSEIDANAQNDGFFVGGLNHEGVTMALCHIQYSGAELCDSDSVTDARGKGEGGMLGLLQVYESSGVEFSPEMVQESIADSTQVEIGIHTEQKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQJ2</accession>
    <name>A0ABQ8VQJ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_739810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="21708" checksum="59F827B16D2A7446" modified="2025-10-08" version="1" fragment="single">EITDEELALLHHFALKVETHMSNDTFAALAATFPNDPPASWKVTKKRAEWLARLRPVIYECCINSCVCYMGPHADKKQCPHCKEFRYRPDGKTPRKRFTYVPIIPCLTAYYRSLSMIEKLCYHTTFQPTNGEVHDVFNCHHYQQLKCRNVKVKGQEIPYQYFADSHDIALGLSSDGFAPWRCRTKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR18</accession>
    <name>A0ABQ8VR18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_894009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="147"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="38398" checksum="C87045D01717A519" modified="2025-10-08" version="1">MTPKGDSHTQKSSQQASLEWLSAEYHDLNGDHIDILEGTPTALEFARIVQISRPVLIKRFQASSCKWSNDYLISKMGSRPISVAVTPNGRADAITLGPNGKLYFAEPAVEKMSMKSLLDNLSDDTCSAGDGAAAETYYLQSQNGNVYSSGFFNGQDDLSEFETLRQDIPSDVKWCTEALDKSPEAVNVWIGDGGSISSIHSDPYENIYTVVRGQKHFTLLPPTDGWCLDERLYPHATYVRNAGDLVLQPSPEISPPVRWASILNPHLPGCIPPEAHPIHISVSENEAIYIPVGWWHHVRQSSITVALNWWYDTEMRGMSWVMLSYLRDMKDVPSGNTDNEGSKAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR89</accession>
    <name>A0ABQ8VR89_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_978860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="154" mass="16231" checksum="4DBB4204DF567DAC" modified="2025-10-08" version="1">MASSSTGTSGDAQGSSSGASGTSGVIESDGITMNDGHKLVQPSATAFVRTRLSSVPPTSNTVRFFLRSCSILSCHFPINAAGEPYVLNPLLLILMSISILSFPLLTLPPVSLHPSAPFEHISLVDSSRPPPTFLLKPLSTHIFFILPSPRSTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRD3</accession>
    <name>A0ABQ8VRD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_107724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="496" mass="55755" checksum="B605C62C0093935E" modified="2025-10-08" version="1">MTLLRLPPRARTADEVLDSDRYSTNTTTSYETNETQSSATTLWGPGTLSGKAIKSLGEASLRGVEKLVVRWRLAKINAILPGLNSGNSSPKYPASPEQLEKIYDDLLELSRLEFYDEKVRQRALRLIMMQIGSREASQLLLCVVKWPKEEITIFLSEMMPCIPLLWYSETSSVVEADTKARLELIAVYRSSLLPSETHEVLPFINLISRLAQEHEGSCRAVIESGFLDILVAVCDHCTFAPAVVTAVQEAIGILIACQQSWIIERAPQRLGLVWPRLNPSAPLRPTSLRMTQQTPNVRKQWWRTTSSNEIIERLSEIAAILSMPELRSNCEKDMFDLSFDLLVFCDLDNDGASFTAISMSYLVQIIAFGGNIRRTLEHVLTLLPYHIKLDFFYRIIHPLSHVLVDPLPTATTFYEVVKVQNPTLNPIDVFVQFAMDVADSSQESAQAVVDAEIMSLIIANRASISNIRYVLQRIRNAAEQHQEPSITLQRPRAGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRE5</accession>
    <name>A0ABQ8VRE5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_163432</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07417">
        <property type="entry name" value="MPP_PP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041753">
        <property type="entry name" value="PP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013235">
        <property type="entry name" value="PPP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08321">
        <property type="entry name" value="PPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="115"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="327"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="545" mass="61038" checksum="15D3CBA9B5444D95" modified="2025-10-08" version="1">MSDTTSTPSSPTSSASTLPSSAPSPELDTLSLSEERIPVSEADIAAAAALKAQANKAFTSHDFPSAARLYGEAIEKNPNESTLWCNRAYARMKLEEFGYAISDASQAIKLDPKYAKAYYRRGTCYLQTLNHQKSISDFKKVLALEPQNNTVRLQLQATQKLYRKLEFEKAIELEGEKNPVDRCHEIIAEGGCELDKAYTGPKLNVTDEGKYQITPEFVEGMIEWFKNGKTLPKRYVWEIVLGAYEHFVKEESLVTVNIEEGVTCDVIGDVHGQFYDLLHLYSLTGKPEPKHYLLMNGDLVDRGSWSIEVILTAFAYKWLYPKYMYINRGNHEAKDMNSTYGFEGEAKHKHGDQSYKLFAHVFTTLPLATLICPTQPPRTKKTNDILSPEGRRRFFVVHGGLFSKDEVTLDDIRKIPRVGRQPGQQGLMCELLWTDPQEAPGRGPSKRGVGIAFGPDVTKRWCTLNGVSGILRSHEVRQNGYQIEHNGLCTTVFSAPNYVDQAGNKGAYVRIDSFGEQSYVQFEATPHPPMKPMAYVQGGLGSMMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRG4</accession>
    <name>A0ABQ8VRG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_108136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="646" mass="68815" checksum="B8A5FEB16AFCCD03" modified="2025-10-08" version="1">MGHSVPLLLESFPVPPSFLPPSTPRTPSSLSFNHANIGEPINEPSSSISSTSSIPPSSSVSSISSTSSNPPPSLPPRGPLPPVPGRSRISDHEAAHLLQSRRSSKYSINSSHSGNGGYDRPDSVASFASARSNGASYAYGHGYRDLETREGRRVSKGSGRVRPPEVQVTTEDAEDTNQAYGGLRIDEEDDSDVQLTSLRLSISPMPPSPTDTDNELEIPSSLSTQFPTPPPLSPFALQQANAMQKRISSSAASTPIKWSAPPSPLYQPSPVPPPVRSTSPNESLAEISMHDLPSGDDGAESEWDVPTTKPPVVQAFHTSRVSGGGVPPPSSFTTSVPTRSDSRSSLRRMARISVDNLDNVSLKASIISPSVSITPSKPIGSTHTQPDPSSSMPSPPATFPTPPTTYPTPPSSSATYSPDIEIDLHKSLHRELRSARSRSRSHRERLISGIASPSSPPADVAWPPMPPVPYAAEFSSRPRRKASQASTVSMADNQSTADSDDGRASPDVQRLLEQTPRPRRSLSMKRRTRSSVGTSSTKGSIGRRKSGGVGSDDGYDEFGGPSLLSRGRKESRRRLGHNEDVEAKLQKLERELDGIGSESDGENVSRRDSYGDGFGFGTYEDGVESEGDGLDSDASDSSLDLHTPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRQ8</accession>
    <name>A0ABQ8VRQ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit Tim21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_755099</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TIM21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.320">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit Tim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013261">
        <property type="entry name" value="Tim21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038552">
        <property type="entry name" value="Tim21_IMS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032:SF6">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08294">
        <property type="entry name" value="TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="36181" checksum="6EEF71147BAE83DB" modified="2025-10-08" version="1">MTSLFCRSHSRCLSLSRLTKPRTSTLRLTRRYATHKDPLHPSQLSQSLDTKYQLRPDQKVGPFQMGMNESPFATPKPTKWADLSAGGKIKRTTARTTNLIVIVFGAGLTAVLLYAVTSELFSKNSPTVLYGESCEKIKTSPQVARYLRGPLSFHMTPPSAERPRGRQHQVASQIFLDSNGREHMAISFFVQGSSRQSEDSYYDVATNWISETVKHLPELTLDDAIQGSKDRSANAWEKFVQSFKYLIGAPTPRPSAPESSPSNNEPVHRPSEAESRTQKWTGIFSSLRKTRSENSLETVRSSENIGTVYTDGEVHAEFVRVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRZ9</accession>
    <name>A0ABQ8VRZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_864298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="42513" checksum="C7AD02F94B2BA5E7" modified="2025-10-08" version="1">MVKADKGSSGYTVGRYRKVLVQKAGGPAAWDALGTKERTYRIDKMRKQIIRDIGEMEFEKLTEAEKAEVDLILWAGCCMHKEMNTFKGGCIGLDEYWNGHPDLPPPILLPNRDNAAAIEKAPGTEAAERTTARSERGAIKVASLAGAGFQHKDRKRGQQDTLRFFFDEKLGFNLAFPDTSNTRFQSHAEACALIITHMDLFIEFLTYVQHKKGTGKLNHMEQNVLAGLNDPPTRQEFCVITLYWLAISVPYMQEIRGPHAKEDNILRLEDFHQRVIDHIDALIKEPEHLLGPDVSAAQKHASEWLPQIRNLLVHFLKRAKDSWLRFISEFEEGATPEQIECAWMDKTNDLNEGAFGTYRQTSRANPTLSLTQYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSA8</accession>
    <name>A0ABQ8VSA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.256</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_815026</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = a alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29543"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19512"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="ChEBI" id="CHEBI:132523"/>
            <dbReference type="EC" id="2.4.1.256"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:29544"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the ALG10 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.256" evidence="4 14"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016900">
        <property type="entry name" value="Alg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989">
        <property type="entry name" value="ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989:SF10">
        <property type="entry name" value="DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04922">
        <property type="entry name" value="DIE2_ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028810">
        <property type="entry name" value="Alpha1_2_glucosyltferase_Alg10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR028810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4499262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="456" mass="51838" checksum="1F090C9CD5910340" modified="2025-10-08" version="1">MSASYIVYCAACISVLKELNNVVTEPYMDEPFHVPQAQAYCGGDFATWDPKITTPPGLYIMSVLFKRVFMFKCSLPMLRLTTTLTLLALPIVLTRLLCFYRRIRPPASILAPTLDAIVLSLFPIAWFFGFLYYTEVPSLVFVVATIVAASEDRHWLAGLLGLLSCTFRQTNIIWTLYAYATSQLMYLRYRRPGPGSQDIAKLHDPDADQARPVDLYRSVQSLPGVLPDILSVFVPYAFVLSVFVSFVVWNRGIVLGDKSNHIPVLHVPQVYYFLTFSTAFGWPVLISGAGGIPLMLRKIYARTFGSKFRALITLVSLAAMGFTVKLYTIHHPFLLSDNRHYTFYVWHRIYMFHWLAPYALVPAYFVCALAWFLRVGSEQSMLQTVALSICVLATLLPTPLLEPRYFMIPYLLMRMQIVNVPSWALVLEGLWYAAINVVTMGVFLYLPREGVGRFMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSB8</accession>
    <name>A0ABQ8VSB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_931332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="465" mass="51656" checksum="53AD29A5227CC102" modified="2025-10-08" version="1">MPEPDITRIAIVGAGIGGLSAALSLRRLPNVDVQVFEQTHVLREVGASIALGPNGLRGLEEMGALNAISDEIAFRSDHGYPMVHKHWKTGKVLVKDEHSPFVTERRHHTARYFRPHLQQAIADIIPADRIHLGKRLVSIDVGLFPEDEPDSSSEGVFLTFQDGSKHVADLVVGADGVHSVHPPFPSSSTVQTKTHRSQMALRAVFDEVYIQDLIVGNPELRNSVHVVGPDRNFFSSMLGKGKFTVVGLGYYPVEEEEEEEERNSAWKGKKWDDVVDVESFRKEYKDWNPWITDLLDRIPSNSLRVHPGWASNQVPPPVYAGRIVLLGDAFHPHGGAFAAGGSLAIDDSIALFLSLQHVQQQSSTPSTSSSSDASSDSRSKVSARRRLSTSELSHALDLYASTRLPHTGRVFSVVERMRDSVAKPGRVWDEEKIQEWARDKKEVVWLHEHDVHRAFVDALNSEHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTD5</accession>
    <name>A0ABQ8VTD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_758872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="30080" checksum="2C31D0CFA90F4382" modified="2025-10-08" version="1">MGSINVNQFVDRELLRGVSIGFYDPVVQDQAQAMAGVMPNIISLPYGKSPPLHLQTTSWRHLLKLMARLSGTRIEPTAQATQRNEDLHLRTVIQFVRPHYNSSTWRTIIWFTIDQDAERPHLRRSSNPSGDVESLPYSYSLMKLPALLRDGSDSLLSKTYTIPSTHSVPYPVLPISFPNLTLYLQAALDESRRYFNDSSSGMRRFAKMLEHCYPDEFDSGAGANERSRVTGLFKKVIGRGGKSSKKGRGGNEETYDLVTPFVPDEWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTK8</accession>
    <name>A0ABQ8VTK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="52208" checksum="E3261AF402DB6231" modified="2025-10-08" version="1">MPKRKEAPSSESSGQEEESSSSNSDSDIPSARKPSAYSSLKALALRNLALGSGKGQSSLRSAAEAESNSGYKNQKNRSSSSGSSSASHVPTKKRKPSSSKRAVTPATKPSKTKSAKEQKMSVLGKTEDALHFGAIAIIPEPITNPSTDKLGPIPYLDLSSPEDAGMFDDMRLRKLRTHKTAVIDRIDGFYVQRSWTHSELMDYVTKLLPIPMRYLSLSGRWVNPFYDRKDPDSNPEFFGPLTLCIISRARVSSVTEDLASWPNGEYVYQLSMSPRRNTWRDNVLIFAPRVSLADPMVKWARNENPIPAPRPLSDDENFPSAITSINEEGRYGKSGVKEAEAIQAKRRRPIHTYKGKGKARAASSSSAGELSDSENRGADSDEYPGMKEAISESLATTRSQSTFIQQASQSASTSQAPAFVYVNDLDDSMNIQETITASLEPTTPPVHVPTSPSIMNLSFVNDTIDSNAFTAAFNDFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTP4</accession>
    <name>A0ABQ8VTP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="63"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="408" mass="46074" checksum="B084388579382134" modified="2025-10-08" version="1">MSNKDPALNIILQKIRLINFVEHADALRPGHKPIIVSIPEDTSKFQRGGMNVHIPLTFSDGVRWLARIRQKSTPSTRLILESEIQTMQFLNAAGMQVPNAFMPRGETYVGEELHFFFVEYFQGTSCNAPIAQGSLTIEQQHDLIDSLARFYINLSHISFTQSGFLVRDPASGNLEVGPLISLDFCQEDRLPGPFFFGPFRSSAHRYLAQIEHVLREIEQGSRAFAGDEDVISVYVTHLWLKDLMQNSPRLWEEGEQTFLKHADDKGDQIMVDKDGKFVGVIDWEWAYTASKSEAFAAPLARVDVNPFFDGINDLSSNEEHLVNAYNKYGFPDLAKCVRDGKVYQRLPMVIGQQPDLVQLRALEHALTGKILDCAVNTELGEWIEDMASGRYRMQVLALKKIKVVAAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTY5</accession>
    <name>A0ABQ8VTY5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">biotin synthase</fullName>
            <ecNumber evidence="4">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_755353</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="BIOTIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976:SF2">
        <property type="entry name" value="BIOTIN SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01060">
        <property type="entry name" value="BATS_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01278">
        <property type="entry name" value="biotin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="64"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4499032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="375" mass="41656" checksum="F8340F23668E9E6E" modified="2025-10-08" version="1">MFRLSAPKRTILFRRYLATHAVPIPSSITRHDWTRQEIQEIFDTPLMDLVFRAASVHRKHQDASKIQLCTLMNIKTGGCTEDCSYCSQSSRYSTATQASRLLDIDPVIEAARKAKENGSTRFCMGAAWRDLAGRKRGFERILQMVREVRGMGMEVCTTLGMLSPDQARQLKEAGLTAYNHNLDTSREFYPQVITSRSYDERLNTIDAVRDAGISVCSGGILGLGEKDEDRVGLIWEVSSMPEHPESFPVNALVPIAGTPLEKNEPVSYHTLVRTIATARVVLPTTIIRLAAGRNTMPESEQAMCFMAGANAIFTGEQMLTTPCSPWDEDKAMMDRWGLGGLQSFEHVNVARKEQPAATLLNEHRTKGGASVSMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV37</accession>
    <name>A0ABQ8VV37_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_914298</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1019"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1076"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1176"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1265"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1289"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="510"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="730"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1037"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1351"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="413"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1611" mass="179452" checksum="5871A8F5D9754CFD" modified="2025-10-08" version="1">MVGNLVAQFSTRLDISRLAPSFSDNLGTSSTDELLSVYATAVSGILLVFQFITLTILGLRKPAVAHSGSQSGRTWAGTYFEQPGGIIVFVGFRLVAALVLTVLSFVSLKQFGNNDATSVNLALFITLVYTVILTVLSILSLEWSTILTRHANTLWFICFLELGFRDLYPLATFDRTPLDSKEGWLIWVKIALLFILAIVIPLAVPRRYIPFDPKDPSPTPAPEQTTSLFSLVFYFFLDPVLFEARRVSHLPYDHLPPLADYDYAKNLRWRAFQHLDRFSGLGKRRHLFFSLMRIFWKEYTIMSLMTMVQAGADLSVPVGVNQLLRWELHFDSLWKVLIALRSYIERKGADTTIQPWVWIIWLLLGPTLSSIAFEWYIFVSTRSIVHTESIITQVVFEHALRIRVKAETSKSDSQRFSLSSETASLADSSPASESQDEEGGPHESSASDDETLHSTARSRDDTLHSSSTSGGQSHAGSLKGIPAVKGATPVTGVLSTARPAPSKDLSDSSKNLVGRLNNLVSTDLQNIVDAKDFIRIFALVPIQVTLCIWFLYNILGWSAFVGLGVIVVTFPVPGLLARFIQQAQKARMKRTDARVQVVTEIMNVLRMIKMFGWEQKMNDRISTKREDELSFIKRLRLLGMMTAIANHIIPTLLMKEELNASKVFSSMVVFDKFNNLLRMAIFLTTQALNGKVSLDRITNFLYDTELLDSWSQTEAEPAILSAPPPAPDVIGFRQATFTWSAEEDNNNGLYTPSRRQFFLKIEGNLLFQKGVINMIVGPTGSGKTSVLMALLSEMHFIPSGPESWYGLPRASGVAYAAQESWVQNATIRDNVIFGADFDEERYKKVIYQCCLDRDLLLFEAGDQTEVGEKGLTLSGGQKARVTLARAVYSRAGIILLDDVLAALDVHTSKWIVDKCLKGDLIRGRTVILVTHNVVLVRPIARFIVSIKDGRVASQASIEDAILSNKELAVEIEKDEEAVERANEEIDPQSAPNEPSARDGKLILKEEVELGHISWSALKLFLTSMGGHHTLLFFITFITCFLTAELAENGQTYFLGYWARQYEAVADPSQVNVPFYLAIYVAILVLLILTFCLGFVVYLWGVLRASRIIHQRLVTSVIGTTLRWLDTTPTSRVITRCTQDIRDIDDPLAQMFSTLVQMSLAMGIKFLAVIILTPAFIFPAVFVGLFGAWCGNIYIKAQLPVKREMSNAKAPVLGHFGAAMTGLTSIRAYGVEETFRKEVRVRIDHYSRPARTFYNLNRWIDVRVDAISNVFAAALAAYLLYVGHGDASNVGFSLNMAVGFSGTILWWIRIVNQFEVRGNSLERIGAYIAIEQEKPPVPEGIPPAYWPASGHLRVEALSARYSPDGPKVLKNLSFEVNSGERIGVVGRTGSGKSSLMLSLLRLIYSDGTVYYDGIATNSINLEELRRKITIIPQIPELLSGSVRENLDPFAQYDDATLNSALRSAGLFSLQEEIEDEDRITLDSDVASGGNNLSVGQRQIIALARAMVRESKLLILDEATSAIDYKTDSVIQSSLRHELNEDVTLITVAHRLQTIMDSDKILVLDAGQIAEFDRPAELLKNKDGKLRALVDESADKDHLLEMVKAKEHLDRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVW3</accession>
    <name>A0ABQ8VVW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rpr2-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="25782" checksum="662F622D3B5AAAB0" modified="2025-10-08" version="1">MDVTAKFQSSIPYALQSVSPTLAALHTRKNRRLLAETTGPDFENSCCGKCGLYLFAGDSSTRVVRMKNARRRQKGGTNAPTPTHRTSSNTRARQSTCFQCGWVTEFPLDREPASLFPIQQTSSFKAADLLNVEQPHVPSKSFQTPNDAPRALSSQSIMQGETVSRQLPPTSSQLPNSGFSVPSVQGSRVTSAPKSRSRPKKKNGLHEMLAQNRAKEEKAKNASNSGQSGLTAFLNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWE9</accession>
    <name>A0ABQ8VWE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_914823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="122"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="443" mass="49340" checksum="D01BBF9D3E2CA04D" modified="2025-10-08" version="1">MTGHTPTESLVDILPPLPPAADIPSKFLESAKQWWAAGDKQSAISEERLLRRLPFFRSQKPASPLSDTELSNVGPVIAYSSRVELSNPKHYINTLSMISTSLFQSQSASPSDPPATSPPPAVMLHGYGAGLGFYFNNFLPMAQWAARHNSSVYALDWLGMGRSSRPPFHIKASKKDIPARVAEAESFFVDSLEDWRQQMHLEKMTLIGHSLGAYFSVVYALKYPQRVERLILLSPAGVPRGPDHTVPSSEVDPPTTTSSEDRAELASNAKVEQVEANQRTAKAKESRSRRILTHLWEEGFSPFQVVRTMGVWAPWMVGKYSSRRFSTLSEEETRDMHDYILNITLAKGSGEYCISHILAPGAHARMPLVDRIAALHKDIPVTFAYGDQDWMDPEGGAESVERLRQAGHGQGKMYIVNNAGHHLYLDNARVVNNLIIKELERKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWI0</accession>
    <name>A0ABQ8VWI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulator of G protein signaling domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_812477</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04450">
        <property type="entry name" value="DEP_RGS7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08708">
        <property type="entry name" value="RGS_FLBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058855">
        <property type="entry name" value="RGS1/SST2-like_Fungal-DR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25889">
        <property type="entry name" value="WHD_Fungal_DR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0734">Signal transduction inhibitor</keyword>
    <feature type="domain" description="DEP" evidence="4">
        <location>
            <begin position="240"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="403"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="637" mass="71377" checksum="48D07683EFE7270D" modified="2025-10-08" version="1">MPDTDPQASSHMMKTTKRGRPFLKDTLDLFATLIVSLQLAPHKQFFRTFPNSFSTDEAAQNLASLKFSQSNRGPDPREPSRVVTTTTTTTFSMTRDMAKAMSQHFMDARLIENAADPSSNLFKDRGIYILTPKGLHVLERFISKNGINSDHLQNVFITQPICIKLLHLERRSADDEIIVSQSVITALFRRFVGRQANYPSQTTQPQDAFQRYNERARGVFLMDVTERAQPLLGKGQQHHKYCFAAVTALEWLCDFTSVVGREEAAEMAAQFVRFGLITLVSDKRKNNDSAIIFTVRGSAPGGNSPVSQHGEFRCTAKAIYKITDEGRRVAHWDGSRPLGAHDSPNASSASLNAERSSVDNVSESGEKKGSDAKIHRRISMAEKLNANYQAAEKKNTKESNTERLNYILEEPSLRSLFREFLRSNFCEENLSFWLDVQDFKRKFNITSSAVAVNPPPRSGSRTTPGQAAMERHHESLISTAFVIYNTYLAPSSTCELNIDHGLRNELVKYLDDVVTSLDGKPFAGKVEPEQANAFNATQLQTMIRLYERIQVHVFRLMATDSVPKFIKTPKFLAMRNWVEDFDPTDDDVRLLSSGPSQPPGLGNNEESGGAYITISQQASEREHRQQQAHTAPMGSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWN6</accession>
    <name>A0ABQ8VWN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-diphosphooligosaccharide--protein glycotransferase</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C8R41DRAFT_808947</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="18">
        <location>
            <begin position="23"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="19">
        <location>
            <begin position="570"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ4500794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="776" mass="86037" checksum="C660789F36D2651A" modified="2025-10-08" version="1">MSTAYPLPTNISPTTVANTASLLRIVAFGLISGAAIASRLFAVINFESIIHEFDPWFNYRATRVLAAKGFYEFWNWFDPTAWYPLGRVVGGTVYPGLMATSGVIYNFLHYFNLPVDIRNICVLLAPGFSALTAWATYMFTAEMKDPSAGLLAAAFIGIVPGYISRSVAGSYDNEAIAIFLLMFTFYLWIKALKLGSALFGTLAAVFYFYMVAAWGGYAFITNMIPVHALVLLLMGRFSGRLYVAYCSWYAIGTLSSMQVPFVGFQPVRTSEHMGALGVFGLLQIVAFASLVRSHVSSKQFQNLLAISVVTMGVLGAGAFVVMTYKGWIAPWTGRFYSLWDTGYAKKYIPIIASVSEHQPTAWPSFFMDLQLLIFLFPAGVIMCFRELRDEHVFVIIYAVVASYFAGVMVRLMLTLTPVVCVSAAVALSTLLDTYVEAKEPDVPEERMEANGSSAPDGKKTKKAGGAVGSQASTTAVAAASSAISDFVSATRSSASTPRQKGIWGADTRLVILLNAIGMLVFFVFHCTWVTSNAYSSPSVVLASTNPDGSQHIIDDYREAYYWLRMNTPQDAVVMSWWDYGYQIAGMADRVTLVDNNTWNNTHIATVGKAMSSPEEVAYPILRKHDVDYVLVIFGGLLGYSGDDINKFLWMVRIAQGVWPDEIQEPNYFTPQGEYRVDDRASEAMKTSLMYKMSYYRFSELYGGGNAVDRVRNQQIPKVGPTLDYLEEAFTTENWIVRIYKVRKEDTLGRDLKTANAFAQGKKKKRSKPVSRRRAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX50</accession>
    <name>A0ABQ8VX50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="31986" checksum="0D91C1A57E123B70" modified="2025-10-08" version="1">MTNSLSTTARGVFVGIERAAAASNSNSAGVGGGAGTFADVMRTSGMVCYDCGLGTVTWIHEPTRPADFSYKHDAKHNSILTVTSLWDGKDFDENVLGAFQRVLSDSQLGPAPLHHLRPIFFHLRQRARLARLHVRLLEILEIGDHEGGMEQPHQNTTNAYQDPMNIHLDLRNSLKRHLFGYGQLMRLRMKLSLTYFAWKLSSLDIMKQSQYGAIAQRLLAQISHQNLEVVIQHLIGVINVIGRVSSGGRAVAPNIPFILRLILQSSLPSSSPSSISSSSPPSPEDLTLIAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXJ8</accession>
    <name>A0ABQ8VXJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_751835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="88"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="497" mass="54828" checksum="7B8639DB2B5F270B" modified="2025-10-08" version="1">MSNTQSIAPVPIDQIVKATNILQKSSAPKFGHELLPYFSFKQGFLNLNNGSYGALPKVVTEACNELMAWQEENTDFYYRIGFIPPLIGVREQLAQLVGASDVDELVMVPNASTGLGVVLRNFLWQCGDTIIRCNTTYATVYKTIQYIHDVTPGLEISEFQLLFPTTRQAILDGWQKHITSVKANAPQGQKIVAVIDSVVANPAAAMPWKEMVKICKDVGIWTIIDGAHSVGQEDLHLADCGADFFVSNCHKWLNTKRGAAFLWMPKESQKIMLTTIPTSASYVTPGPDRPETNIVSQFQYNGTIDYTTYLSVHVALQWREWVGGEAAIHQYCNNLAKQGGALLAQTMNTKVMDPNGEFTMAMVNVTLPFPSDFQAQYDASVGTALSNKLLARNMYAVTYYHNSLWWTRVSAQIWNELSDFSILGNALVTICSEIVSEHKNANVPQNCKAVSFSSYLEQPLQGAVALDSNNGIGAPRPVTSTKVTLVGYHTQLASIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXK8</accession>
    <name>A0ABQ8VXK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_808178</name>
        <name evidence="2" type="ORF">C8R41DRAFT_852760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF5">
        <property type="entry name" value="FAMILY ACETYLTRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="237" mass="26378" checksum="2E9123951D9D731C" modified="2025-10-08" version="1">MSTLAKDNNFCFPIPNILETEKLELVPFVPSYATDLIQGLDESSWIHVPVGPYSSPDEFVEKFWNERIRPNDGSYLFVALNKSTLSATDSGEVIKPTVAGMAGYVNTETENLCTEIFIFVLPQFRHTHVASHAVGLLLRYALNLPNEGGLGLRRVEWSANVTNPASIRLAIKMGMKVEGVRVWTAVLPMNKTEAGNGRALRKGDPRAEFPGRDSTLLALCWDDWDKEGKEKVEKILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXL8</accession>
    <name>A0ABQ8VXL8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_812738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="64" mass="6961" checksum="FB3D1046ADF78F91" modified="2025-10-08" version="1">MHSAGFVHRDISAANVLVKDGNAKLIDLEYSKRVQPGIQSGTSDVKTGTGVFHTCRSYDKQILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYN9</accession>
    <name>A0ABQ8VYN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Centrosomal protein ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_892166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="248"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="34808" checksum="790F540B65054E1D" modified="2025-10-08" version="1">MNFAYANHVPSSFAGPSSSKLQGPFDDGKKEKRRKDLSGKVVKEISERREDGRHYTENINVLVSTTASLSTNPSLVPSYNLRLLPFTISRSALLYQDELSESYSLSRAQTAFLEEQRKVEDEWKKGRDRVRERLLEGIEERRKRAREDKEGEGISADATLDSQNRPHITRKLRNKMGTPPPMTPLGSQLGSAAVSSAGNPGAISSFPITSGPFLNPHSLSVDEIPSPFPLALTATAISSGSGGNGGSGALGANTGGGSASGPGVGGSASTTGGRRRPKGSGTHQSQAIGGLGKSLAMLNALKDTEIEADLGEIRRGNKRRRAAVAAGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYT3</accession>
    <name>A0ABQ8VYT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RabGAP/TBC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_805024</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF502">
        <property type="entry name" value="SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="492"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="850" mass="96599" checksum="C6F3CFED56E2948A" modified="2025-10-08" version="1">MNEYTLFQHSSPSESTISTSSTNSMVEIKRTDPPQHLANDDKEDSKYRLLYTKSKVYVNPTAYARDNIPGFISLVKRDAPNPSYYLAWIPETLLNERGATEWDKFVKVEEKADLDDEDNDVVLIDLPTQRPESYAFSVSLTQVYSLLVYPPSFSSWHGSIHINLYSGTTLPTLYFHDNESHSFTMPLPKSPQSHTRSSITAYPPPPSLSSPINSSSSWGGEDFIARLKCYAHVLRSNLQPSLFLVDPSRSDIETHSTQIFDDDAVDDILAQSSYANSHSPVPAHRKPRPLSSPPPTSSLSPNPYSHRSSVLHRSLGSMSSNAQSSSQARMALLQSFSNITRATRHAAQNILSHPLAKPIVPHLPDPVKSLVNVNGDLKWGSWVEKGGVGEFESARVYLARWARIVAEEGERARRRESQTVGASTSSSVTEETSSLGVFELLHSASNLPTPTTSRDPAHPVDQKCWFDWFGVDGRPKVRLEEMKREVFRRGVSDQGRLRQIVWPFVLGVLEWDVTGEERDAKWDAKRKQYHALKDQWCGVPEVFERADIIDERHRIDVDCRRTDRTQPLFSTPSGTLPNKSSETDDEKARLQRFSIISPDLVDIGSQSPSNEHIDRLAGILLTYNLYERELGYVQGMSDLCAPIYVVMQAEEEMTFWCFVEVMNRMKQNFLRDQSGMKKQLSTLQQLIEVMDPELYRHLEKADALNLFFCFRWVLIAFKREFPFDEVLRLWEVLWSDYYSNYFVLFVALAILESHRDIIIRYLVEFDEILKYCNELSMAIELDSTLAQAEVLFLSFAQLVADIDRRQAEESSSSLQGLRHRGTDVAGELSSSSPKIVLSEYLRDLLKAGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ03</accession>
    <name>A0ABQ8VZ03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bestrophin, RFP-TM, chloride channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_976581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF21">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="209"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="428" mass="48064" checksum="1D12839C4DF7ED34" modified="2025-10-08" version="1">MSDIGTKGSAKRTLTSVLPSLRPKRKHLRKYSWLPDVFRIKGSIISRIFWPVTTNTLFATIIAYAWHNGYRIMLTNSVVPLLSVVVGLILVFRNGSSYDRFWEGRKCFATVISNVRNLSRQIWVNVALPPSDQDDTPSKKGKAPVPTASQLHRIKSEALHLCLAFPFALKHYLRGEDGLSWSDYHDVLPKNFARFDEVGYQKSKSDLTTSYHTISNKSSGRSSPDLGRGDATKRVRPKRSKQNLPSQSTPLLSDAVTHRTVEFRPFADDNSLPLPLIIAHEISRLLFYFRREGLLETVGPAGMNAMNALVQSMVDNMTAMERVANTPIPISYGIHLKQCVTLYLFALPLTLVNDLGWMTIPIVTVVAFTFMGIEGIADEIEMPFGNDPSDLPLDRYCHDLKEEILYIIERLPDSGEGIYGYDDGEGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZQ2</accession>
    <name>A0ABQ8VZQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WLM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_892703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="2">
        <location>
            <begin position="8"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="457" mass="50178" checksum="27D4E6CF38EB8B36" modified="2025-10-08" version="1">MVHSRFNEKETSPNPYINFITSLPAEDSEDARQFLRALAAQVRPIMKAHGLTVNSLEEYEHNAVFAGRNWESGETIELVLRRPGGSFLPSSWLMSTLCHELAHNQHMNHGPAFQALWQELRNEVRQLQNKGYYGDGYWSAGTRLADSAVVSGQGLDVGDLPQYICGGAQSRTRPSNLRQRRGPRPREIMASSKTGRQTAKKRKAGSRVTSKYAFQGEGTSLSAGEAGKGFGKQAGSFSKRAREERAFAAQKRLQSASALSSSAAHLTSPTASTSYASDEEFLEDAEIITETDADRKQTLLATEKDEDLKNLHSGTSWKDFENDFIFTGRGRTNVAVISSDEESDPFSATMKGKRKADAFEPLKEPSSKIFKNANSKSGLRLGNLVKTEVDFRKKEALGMTPVQGEGRTIDGSESGNQKQNSANFSWPCLVYISSENQPLHLACAACGTEKGHNILNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0C7</accession>
    <name>A0ABQ8W0C7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_892530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00148">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005455">
        <property type="entry name" value="PFN_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027310">
        <property type="entry name" value="Profilin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604:SF0">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00392">
        <property type="entry name" value="PROFILIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01640">
        <property type="entry name" value="PROFILINPLNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00392">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00414">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="126" mass="13250" checksum="1E251B8DF542F498" modified="2025-10-08" version="1">MSWQAYVDTNLVGTTKIAQAAILGAQGGVWATSEGFEISPDEQARILQAHSQPSAVEASGLIIAGVKYFCLQANERSIYLKKGADGAIVVKTTQAILCCIYKAPAQAPEATTIVEGLADYLIGVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A1V7</accession>
    <name>A0A9W9A1V7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8J55DRAFT_520296</name>
        <name evidence="4" type="ORF">C8R41DRAFT_844505</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000027">
        <property type="protein sequence ID" value="KAJ4472523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A1V7"/>
    <dbReference type="OrthoDB" id="274726at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4477927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="87" mass="9758" checksum="D049E6DD5FB228BB" modified="2023-11-08" version="1">MSSELRYTANTQLEHLHARYTGTGHADLTKYDWLTHQHRDTLSSIVGHPTLTAYLAIADGACTGRVKYEMTEKMLQPCGPPPKKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AFK9</accession>
    <name>A0A9W9AFK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar sorting protein VPS24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_454438</name>
        <name evidence="3" type="ORF">C8R41DRAFT_790125</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AFK9"/>
    <dbReference type="OrthoDB" id="2329734at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="216" mass="24500" checksum="09AC5BD53F9514A3" modified="2023-11-08" version="1">MQTINRFLYGPTPEEKVRAWQTKLGQESRKLDRDMRQLEVETGKARNTVKQLAKKGDVKSARILAREVVRSQRQKDRLSVSKARLGSIGMQLKQQLAMAKVTGSLQKSTEIMRLSNSLVKLPQVSQSMREMSMEMTKAGILEEMMEDTLAMDDDEDLEEEADEEVDKVLFQLTDGKLGQAGSVNTELPPVEQSPEDEEIERNLEKYRQELNGILSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYB6</accession>
    <name>A0ABQ8UYB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_783158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="36573" checksum="F10048F08C7E8868" modified="2025-10-08" version="1">MAIIDGSHGGDEISQLWAVITELSDQLNQNRSASVSLYAQAGGVKNQALHSQTGFVLRKFNADKPKEIYDSELERMNASMMVENQSLQHDNKQLNTLIKEYEQTLDTLMSTFRNRAQTVQENELSLIRHYESHLLQLEEENSSKELEASTRISESISRLSELLRNCLREVGGERTRLSTYDDHENDSETEEDPDLLEREPWQSTDATHAEWALEREIELARLERENEELRNLIMAGRAIPVHAPQVAHPAPTQIKPQTEEPLQPSKGTEPGSQLGTKVEEVQDSSARDRPTPQPHGEEDLDTVPEGDLLNVDPYATVKRSKMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYD2</accession>
    <name>A0ABQ8UYD2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000146">
        <property type="protein sequence ID" value="KAJ4464141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF1">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127053" evidence="1">
        <location>
            <begin position="20"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="28393" checksum="196869394A324CA4" modified="2025-10-08" version="1">MHSSTLVICAAILCGIASAHPTEAVPGTLAARDCSAEAAALNVARREKRGLPPRSIYPTMPNEICVLAPEIAKENYVLSGSVVRNDVTDGEPGVPLTMDIGVLDISTCQPLPNAMVEIWSTTEGRSTYPRLLAANAQGEYSPTALRGAYPSAANGIAEIQTIFPGFNSDGANHMNIAVHSGNSMNSSTSHNGRVFFTDGWTNIISMSSPPYQNNPNTRTLDLDDPVYVEANSNGYTAVVDIEEIEDDWPEGIVGYITVGINPSLIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYD4</accession>
    <name>A0ABQ8UYD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_127970</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000140">
        <property type="protein sequence ID" value="KAJ4464488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4464488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="548" mass="62110" checksum="09C16784B9E11C62" modified="2025-10-08" version="1">MSYFNIHFAITALVSIAFWRFLRRKSKRLLSNISGPPSPSWFKGNFQQVFNPDAWGFHEFLAEKYGSMSRLHGPYGTNTLYTFDPKAMQSVLVKDQDVFEEEDGFIKGNLLIFGEGLLGTLGHQHRKQRKMLNPVFSAAHMRAMIPVFFEVTHKLESALRNRLQAGPSTQEVEILSWMGRTALELIGQAGLGYSFDPLTDEESAHPYSQVIKELFPTLIRLQFWQFNVLPYVSWIGTAGFRRRIVKMLPWKDLHHVQDMVDYMYGVAEEIYKMKINAFKAGDEAVALQIGRGNDLISVLMKENMKASEEDRLRDGEVIDQMNTLIFAAMDTTSSGMARILHLLSQHPEAQEKLRQELIEAKLLKDGHDFSYEDLTTLPFLDAVCRETLRLYTPVTTVTRRARRDAIVPLLRPIIGLDGTEVHEVAAPDGTTVIVSISNSNRNPDLWGEDAGEWKPERWLSPLPQALLEARIPGVYSHLMTFLGGGRSCIGFKFSQLEMKVVISTLVEKFQFSPSSNDSKIFWQMNGVTAPVIGKDNHPQLPICISLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ31</accession>
    <name>A0ABQ8UZ31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="15634" checksum="083B485B9F7D8466" modified="2025-10-08" version="1">MNSPIEPGSPTLSTPSSGSDVEEISLPPSSSFSSGLVINSIGSFGNTVPSSATSSSSKRRLNPGSVSSRDPRDSKSRRRDNPHHHAKGAGGEGERERDRERQGGRGANYEMQKEKREKDELLDMGAVEYLRKEIGDPFVEISFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0S7</accession>
    <name>A0ABQ8V0S7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_925999</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4466716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="53606" checksum="D8BC6FCABCF9D35F" modified="2025-10-08" version="1">MLDPSYSLLGTIETPTNSVNALAFSKDGRYLASCGDDKMVRVYDVKHSLSAIWTYQGKSPFTTVIWNKEYLFTGNGDGEVMMFHPRASWFRKQRDKLIAEFFTPIYFLELNRIGNQLLVCSGSRTTLLMERKSGQWKSRSHFDSPSSFEESPDFGEPDGFDEPQVLAISAHFLNEKDCIVIGYLHHGLWKYQIEANAGVLVWGPDEKIGSTVLSPDGAALAVTNIRSGVDWLKVSSSAGVKWKKMSTSTEAQDSTSNIPLPILFIDKGKHIIMATSKGYAAIFHTKHGKKIMSLDHGNDRTWITALAYVHPPNMPQLIATGDGNCGVDTKIKVWVEDTKGKEAESVMKTSSFSLTSLCFAFLSIARIGFCIIGMAFVILLLLRATGLEDIQNSILTLLPPRFPVPLQPYPLPSGYSAPTLANTMLSSGSLPFPESKTITSLPSPLTTISDAIVALAPDTVLITLDTPSTTLQPSRAQSHGVWDRIFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0T2</accession>
    <name>A0ABQ8V0T2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_854369</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="77"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4468507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1259" mass="140411" checksum="0611AF32D125AEA3" modified="2025-10-08" version="1">MSSSASSLSNSSSTSSQLDVDPTALSSARSGVSLNDTSPNELPMSGFASFVAFVSGLERSLHTEEDPMLLDIDFEFSPVQTIITSSATCFVEKAGWKYSSFKGKHKGRWGKFIALKYTCHDTDAARTTVSWKQLITEVRVLLHEPVRYHPNIVRLLGISWGAVDDMQSNFPALVFEYSDLGTLAQFQSNSIGALSFDVKKKLCWDVAKGISILHACSVIHGDLKHENVLIYPNRDPDASVKYVAKLYEFRGSLMDIVADNSRSLSTSAGPWSAPELYSNTVVPEGMLTLTDVYAFGLLVWRTIMNGQNPYQLPQSNAEPMSDSQIFELKRSNELLAIAKEGILHCESSPNSVEILHCVFEHTIQSDPSARNLVRAIAALQVNNASEMEDLLQKRDKKNEEYNEYFANKVPGTHGVTLDSLGVYLAASNATTGDYDYQSAGRGFRAIRPPPLGKFVFEPSRLKTVLDWERQAIILCELEAVASVEPKSSNKPSAPTQINSAIAAFYAFQCQCYEFGTKLSSAKACHWLKLAASREECEEANLARAWCWRFHITYNVLLDVDPLKLLDWIRWSIINGHRKCITESESLVQLMIPGSESRSFWEQAFINARDILFTGSGGVGMSFFLPLALRRTYHMDDMQALQRDIQEELTFRGVQSIDEIYVNSRGDGLLHMAAGLGRPDTLKYLVETYHPTINKSNTSRQETPLISACRGGHLACALYLLDLGAAPGGDVHSLERPLWWLSSFRPHEIPIIAARLVQAGESLTSPRYPSFASVRGDLRKKYVLSDYENFLLLPASPLSRAVMMESLPAVIALLALGADPLEGLRENLNPETGCSVCSVVVAAVLTLPDILKALLDHIDAGPDKQVRLFSEIEMLEMALDCRVTIGDPTSVDRRASRLGPMYKVALASTLRMLHEREKLFKEGDNEAKTVSAARASAIVLSRLASLGRFNIIRNLLELGHSAKGYADVFPIVSAVEENRRSIFRLFVDHGADPLAVYDFPSQKRKRTLLQVVAERPRHARAGIDIAQALLEKGVPVNFVFSDDSIISRPAFASAVRRQDFELADLCLKYGANLDLAYVHQAKSPKSTVFGEMARYPTERNLVSLEYLLRQEKLPSFTVAPSTGETVLHRLLLFWATTHQQRRILERMVRRVLKNDIHISDNILKKEAVGIPFDVALSGNIEVFRALLDCVPSLSQNPILYFEYGGMKLVMLLRAIIAKFPQLPERISVMNTMLDIVSNRNMEMELMERYRLVLYRLEAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Q9</accession>
    <name>A0ABQ8V1Q9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phospholipid binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_97128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000125">
        <property type="protein sequence ID" value="KAJ4465582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13316">
        <property type="entry name" value="PH_Boi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827:SF1">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="8">
        <location>
            <begin position="437"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="911"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="1123"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="57"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="377"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="537"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="642"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1033"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="384"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="709"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="746"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="821"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="871"/>
            <end position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4465582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1261" mass="136486" checksum="6912AB59C003C9C8" modified="2025-10-08" version="1">MPEYVYALHDFSPENDDEVPFRAGERIEIIEKDEAYGDGWWQGRNLAGKTGLFPQSYTAPAPTANGFTTGDDTNDVPSNNTPLHPLDEESEPESSPQAPAIFVNGNEADGEVMKATLTDVQKAIEQLKMNRTSSIDGDGARSFSFASTREDRDTDRESETDYELSDTEHQEFGDDGHHKSTRQRLAEKARKAVEEAEKLEMMMGGISAGNRTSAPPIEVEMSDESDGEDDEDYTHSSSFFRRHSAIEEVDEDTEGNGTAPTRTPQVHQDLTLPEQEIDESEAQTATAPSFPSLSTNEDAADTKSISLPTPTSPGFAHSESTISTVIPIPISAITPQSIPSTPPRTITPAAAVARSPSPMRETLVALPSPTASSFHSNSGAFHFSPHQSQHNSVSSVPSSALATAPVTTSESSQTNFQPSQKDNEQAKEKEKTHPSEWNVDEVVEWVRGKGFGEDVCAKFTEQEITGDVLLELDVNLLKNEIGIMAFGKRVRIANAIAELRRPPSINYDEQVLENPSSPFAGSQSVHRMMNQSPQLYAQSPHSVNSQPYSHPTHSRNQSQSQSHHSFPGSATSMSGFRDSFGSNGALIAAAGLMSPESAPHTGDLLGSPRSDELFVNSQEKALFRPAQLTLSPSDSALNTSVTAISQSTETEEDRAAMSEGEISAGMTQSARRRLFGRSHDSAASGSKDSRRSSFKDGASPTSAAIVAEGDSKEKDEKEKDTEKGKETDGKDGKNTVSGKSHARARKSIDAGKSGERLSIFGGTFSGMGKGRKPAPRYSAASEDAVPPSLGDKSTSGSSFHLPRFSTGPRKPSTRPGSSSGPKEKEKSSSKDLLSPHKEGTIRDPSLLRKRTSSYPGPNPSADAGTKKRSSSESSPQTNGNGQSVVKANGGGDDMPLSPLKPGQSILDQIGEPDHAGWMRKKGDRYNSWKLRYFVLKGPHMYYMRSDSHSETKIKGYINIIGYKVTVDENVNPGKYGFRIEHENDKTHFFSSEEKVVIREWMKAIMKATIGRDYTKPVISSVNIPTIPLMVAQAMNPAPRPPSPTARDATQKALRRENPNQLSSRDARVLMGLPTNSDTKEERVKLESFFSSTTVDDASKGPAPPRPSREARRASVSQSLIPNIPIDDGLIDWANSHLPSSLQIIDTSGAICGGLTILRLAEAIKGRPSSPPVPDSAFPADPGDDKLDGLFRLFDFLLDNDVKMGSVSINDIRQGKRDKVLQLLKALKAWEDKRKAIAQSIGKGAMQAGGFIAPPYSLPVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V240</accession>
    <name>A0ABQ8V240_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="411"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="486" mass="52045" checksum="E5F39A09E489BEA1" modified="2025-10-08" version="1">MTTPSTSVPRLVIVDDTDPTIQYSPSSAFSLDSTGALDYFGNGGPVFNQTLTGTTTNASLSYTFNGTFVRAMLAAVGTTYSWNCTVDGHQITSFTVNIDQVTNYIACDSAGTLQGTTSNHTLDVNLFFLPTNTSNSTQSLWLDSIQYQPLPSDPLDSVMLRVHNSDPSVTYSNSSGGWSWQGFESNSTQRTGTSMNFAFNGSSVSLYSVNFGSPTLFNASTAFYAIDGNTGVNFDLPGSATVQNTGNYSNIINYPLFTASNLSTSPHNIEVATSYNDSKTPQYLSIDYFIVKTNPVNSTSLEHASNSSSTDSTSRSPSNVASRVGGVIGGVIGLAALLFLLYYIRKRKQQQYSGMMLDITGGGPGYYRSGAFGGDTLEVTPFITSAAPPGTSHIPMKYAADQDSTAYTGLPSASSSAAGPSSSGHPRDSSGWDSNRFVMSKRPRILQVEDEQLQRSQIHQHDDSGMRIPPRDEGVIDDVPPTYTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V262</accession>
    <name>A0ABQ8V262_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Dynein associated protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_924910</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="15">
        <location>
            <begin position="33"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="86"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="646"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1289"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1422"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="288"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="601"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1133"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="132"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="663"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1309"/>
            <end position="1320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4470298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1488" mass="162718" checksum="1161BB6A5E2DC81F" modified="2025-10-08" version="1">MNSSTASTIPDPPLGTIVELSSGIGTGVVRFNGYTDFKPGKWVGVELFEKNGKNDGSVGGVRYFSCKGGMGYGVFVRGSQIKRIVGNEREKEGERKMSVSAARRPTLGHQRTSSIGNGLGTAPSSSASSTLRVSPASASGSSRSTSPAKPSSSRLSPTKKSSLSLSSTTLTRPGHQARRSISLKQAPSPSSPNPPRMSSPLTKTPSPVPTSATVAFVSEPPTSSLSPPTTAPEPEPPRPSITLPDTHPQIHALLTKVRVLETNRTLDTLQIQSLESKIAESSSFLSLRPKLQSKLQSQQAELTSLKQEINELKAQVKVWEERKEVVEGELEMCMLDKEMAEERAEIAVGELEVAKERLAEVEVEVEVLREEKELWELENDGEIKPEGKQKDTNTLAYVQLEKQNERLKEALLRLRDMTQDTDQDQRRRIAEMEKDLTGYEELQAQLSTTTVKLSNAETQIDDLKLQLDDALGAEDMLVQLTERNLVLGEKIEEMRITIEDLEALKELSDELEENHIETEKALQGDLETLSTQLSAAQLKISTLSDTCSDYEGTIGQFRDLVVQLQGELTHLRLTTASAESQRGEALSQTAAILSANIRLQSTAAKTRARDVEAELSKMRERELREELEIVEGFLPGVYRDGVAEGEADAGNNLNQNQTHKHTGSSGVVSVSGGEIQDPSQKPTTSPVVGTGGTDRDAVRVYMFFQRIASKADIINRVVAQTHGLPEALDLGGGEDDAVEGVEGKVVTELLVGVCEMRGRLSVLSTLCKRLSAILRRCSPELWISVGRLYEELKPLEKRMDIHVELLGRDEFRERECVSDVIKINAQFNHLAEMYFGDYFGGQLFGPDIAERELGTLTLFDLDLDMFAASIGMMKTSVEGLLKEEEFAPSADFGGFDIHTELYTPLLTLLSRSKSAKISVRKMAKRLEELASSTPTSTSTSGANAALKPHLLPQMEVLSNTVQELVNFGISLAQQTLPYLADVRAGKAAPFRLTEILGFAKQQAGGIVVGGGGGTTGATTTTAVAAKPMLFKPGMLWWEVVGEMITNLIEDSATLLPQTLDPANVLFLSPSTTTAATTTATVTASTTPTPSFPSPPWISRIQTVQTLLTNSLSSTYNHLISQLQSDLISLSRTLKAKDQHLAELTVKIQLLERRAEGKGAEVRRMEEMVKEMEGEVGRLRKVEAGYGEAMVQMQGEVEGLEREVERLRGSGNVVEGGVEHVKGIDQDGVGVSGAGLISAGVTATEGNLDHAQLMDQYTALRNTVRFLRTENAYLRGYDMIREIQALPIIPVPRSSRPPTPPLDPSGLSDTDTDTEGDEEYNDPASRTAPKKSPSSHPLPLLTETKLVYRSVMKYTSSPRVVDLSEVNARRLEVSRRRGLRLQKGRNNSQIEMRENGDMEEVAEDREKDNDVLEGEGVKDTETGIKKLDPIGSTTPEIPRRPSGVWMPRKKMPAHQVLERKIRGERLGERVRGLMERVERASVVRVGGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2B1</accession>
    <name>A0ABQ8V2B1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_827496</name>
        <name evidence="1" type="ORF">C8R41DRAFT_854344</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="75" mass="8451" checksum="F50D0F8269C1681D" modified="2025-10-08" version="1">MIRKAFLRAFCVFMDGARSENWHVPTCPEFPECHASQYPDTSDVSMFGRLDIDDVPVSQCPDINDVLTSRCPNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2B8</accession>
    <name>A0ABQ8V2B8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbohydrate-binding module family 19 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_870782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045555124" description="Carbohydrate-binding module family 19 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4470521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="46701" checksum="53042AFBD5E05A52" modified="2025-10-08" version="1">MVQFTDALVLALLAATTRAAPLSLNKRIAQTTIDSVTPWEDACNSAGGGSQCNPIAVTAAATLLAAAGNCDQQNSADAMITLAKTLDSNADMISLAQVFAQQPRNSPNSLAVPYCETAPQNSELNGFFQCQFQGSDQTSFVGGLSVGDAGTIPFGLSAAVNPAGSCPANPSGPVADGQQLNTITQNPGTPSSSGSTALGSTGSTASSASVAPAAASSAASSSASTSNNDGAGAAAGASASSSSTSAAGTTTSSSTSTSSGFALSNGQAAQALNAQFASLTASSTCTDGQNACVNGAFAQCVGGKFETTQCAGGTTCAALPLVNSAGTSITCTTTADAEARIAATGATGGITGEGSTAAASSASSDTSVTDSAAVSTSTAAASTNQAATSSSSTSSFALSNGQAAQKLNAQFATLTASSSCTEGQNACVNGAFAQCVSGSFETTQCAGGTTCAALPLVNSAGTSITCTTTADAEARIAATGATGGVTGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2N1</accession>
    <name>A0ABQ8V2N1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_926052</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="73"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="299"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="426"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="467"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="601"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="642"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="221"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4466571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="684" mass="74459" checksum="FF6523F78C105231" modified="2025-10-08" version="1">MNVQHLFDEGYNDEDVLILNQYPPTPSKPSSVDLLSGFGSVQECEELAYQILASLPRARLATIQRRLAPLLQFDVVGSLPAEVSLQIFSYLPFPALLTSALVCRRWHVLSNDQSLWKDLCDVRGWSWRQPSYKFPPVFTHSGLGASQDAWNDSDDEGMGDSDEEAEEEEVADTLMMSELDAAKAELTIMHAELDSGFASMSFAGVSQLIASSSSKIPTRASVYPSGNNSNSSSTKRVNNVRPRVGTRHSAPSLLGSLGSPSSSPKPNYKLLHQTRIKLQKRILTSSYRLSALQTRGAPTNSHTNTIYCLQLYTYPSSGVQVLFTGSRDKTVREWNLSTGLVERVISGIHLSSVLSICVHNGILASAGSDRKIVVWDLEKNKVIKVISDHEDSVLCVRFDDKRLVSCSKDRTVRTYLFPDLAPQFVLGAHRAAVNAVSISDTLIVSGSGDRSIRLWDANTGNLLRTFENHHSRGIASIDFKPPYVLSGSSDKHLRLFDIATLHGWSTSPEFDNISGLVGQGHDLGSSQAGHLSSSFVPDFQSQPMPNAGNNELLTSGFNIAPTFAFGLEGQAVLCQACGNSGLVALGGGVSGRQGTNNVHKNVLHRDLVRTVAFGDEFVLSGSYDLSIKVWDRRTGALVADLSGGHTGRIFCIGFDGTKVVSCGEDQRICIWDFADGIDTSFIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V300</accession>
    <name>A0ABQ8V300_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_619814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="177" mass="18961" checksum="B7E2BB2E3FA43CBB" modified="2025-10-08" version="1">MFVINALPKTLRILTWLSIVLSIITFVFSLISKLGVTSFFLGPCISSVTLIYLLTILIIEHKGNTSSSIKAPRNHMRLGSTGDLPNNLPPTTVVGHSAYSSLPSLIIAYFLGICWFLTSITSIILLAAIAWSEIAIAAVAIVSCYAATAQTIVWFALAGVLHWERVQVGGKTTGALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V346</accession>
    <name>A0ABQ8V346_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_905473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4471899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="148" mass="17719" checksum="571E8A282427C5E3" modified="2025-10-08" version="1">MDRLESCLFCYQQVPHTPLFPIRFYKAWRRWQATLSDPCPYKARWLLIIMSIGYVSHPDVQWRNDKSISPVPLLPKLDNAGYQNHPHHCNLLTHLWLSPCRASNHRHLRRLQCLHIILRLHWNMCTCFVRWRTCGMPGWTKEYVGDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3P2</accession>
    <name>A0ABQ8V3P2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein RAP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_54753</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Chromosome</location>
            <location evidence="5">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the RAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11655">
        <property type="entry name" value="rap1_myb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039595">
        <property type="entry name" value="TE2IP/Rap1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015010">
        <property type="entry name" value="TERF2IP_Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466">
        <property type="entry name" value="TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16466:SF6">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08914">
        <property type="entry name" value="Myb_Rap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="TERF2-interacting telomeric protein 1 Myb" evidence="7">
        <location>
            <begin position="3"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="324"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4467308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="476" mass="54091" checksum="F17C440ECC5AB788" modified="2025-10-08" version="1">MKFTEDDDSFLVQFIAESHSEFKGRKGELLYKKLVQQHADPRHSWKSWQHYYVKHADYFDHLIEQYQLEHSISIPPTVTNQIRKRYGFTEAEDALLVEHIAKNDLSGQRKGLSLYNVLSQRDGKQHERSSKSWCHRYSKNADYFDRLVDIYRREHNVNKHLISTLGTPADSSSETSIGISSPSTSRSRPSASLPLLSAPKSTRFKREEDMDLVAYLSENTSLSPGLGLDERNSFKLYSNLTRSNARSWAASRSANSWFIRYTSNMAYFETLIEQYRLRNSTTPCVTLGKRKRDPRVLPSSSTSASSLFEDNSFIGKEDNRQRISYRPRKRLCGSGSSGALDGDASGDAIDKAGTEYNRDEDHNKAYRRSKRLPAAPSSRSHGSDNSGEESDNEEETSAPIEETGSLGRAGSFQWEGAHTLSSLTMRFTRRRLRNSRAQDNDQDEDDDLIEVDSYLRGCSVESNMQECNGPAKIALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V426</accession>
    <name>A0ABQ8V426_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_852895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="109" mass="12230" checksum="045B7BFCE0137EEC" modified="2025-10-08" version="1">MVLTNHICIVTNTVARNHIHTLNTDVVPQNHICIVHTISSSPTTSASSQYGRPEPHTHPQHRCGTPKPHLHRAHNMVLTNHIRIVTIRSHLEPLSCHDMVPINRITPSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4P0</accession>
    <name>A0ABQ8V4P0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_930983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="6"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="183" mass="20775" checksum="95494C0F575F4AC4" modified="2025-10-08" version="1">MSNHLQALPGFYKLLFFYLEPASAIIPAPMIWLWPGAAWFHHEQIPHSNPSFPASESLDPRTAVALWQLGNCYMLVGLIVSLVFRVAEDAFRDNPVAQERIVGATLTAMAITDLLLHKIHSVLSSLIGLPTDIRYDIFSWNGITHGNITFTTFVFCVRLAWFMGVGRRRFYYGQRRPVRVIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4X8</accession>
    <name>A0ABQ8V4X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Casein kinase substrate phosphoprotein PP28-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_898374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019380">
        <property type="entry name" value="Casein_kinase_sb_PP28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039876">
        <property type="entry name" value="HAP28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22055">
        <property type="entry name" value="28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10252">
        <property type="entry name" value="PP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Casein kinase substrate phosphoprotein PP28" evidence="2">
        <location>
            <begin position="113"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="22699" checksum="A24FFD81D2542C72" modified="2025-10-08" version="1">MVRGTGKFKTKRGGGRQFSKNMVLDENGTAVSTDKRWRKDADGSGSDEEEEDEESEEESEEEEEAEEADKSELSRAERKELKKKQAAEKMKQKQKQAGGGGDDDSEDDSDLINPNHVKSKMNISDLSAPRELSRKEREAKDKKEAQDKYWKLHVAGKTDQAKADLSRLAKIRADREAAAEKRKAEAEAKKSELGAKQKASGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5N6</accession>
    <name>A0ABQ8V5N6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_964983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="138" mass="14267" checksum="B67FD4DCBED66CEE" modified="2025-10-08" version="1">MKILLCKGMTYASPAGPSALLHSAQNGDNLDPKELGACSQGVFMMLDALSMVEVDLGKGRKSNECRAARALNELADIDWVDPSEDEVKKPSSTPLGTAGAISSKLSNGMSNALPQSSPSKPTALANPNPAISIAKTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5X5</accession>
    <name>A0ABQ8V5X5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_855636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="57754" checksum="430DCC2019185074" modified="2025-10-08" version="1">MSSSTITVTVLISNHDEESFIMQVYISSLCRNPPFSLLSVKVPTADGVFDILSIQGTRNKNIRHRQDARFKTVCTLDRLNRSPPSLLTTICIPVMVVSPRVDYAAASIMFPSTGMQALSFLIYILGVSILSHCLSRRLAAEDWTSWNSIKDMTWARVCILLIFLDSWLFLFASGILTFGVGLESKEVVCEMAIYLCIIFYATSKLLIYSFLVEKVYLVWSPTVSSPQRTKSPIYLGCVAMITVYAGVIATMFAGKIFFLRESDGVCIIGLQQYSSLTLVVYDLIINIVLTLLFLWPVFKVNLMNPRLKSVATRTMLASAVALTTSTVNMLVLALLKGHENGWICLGSCGADVIFNALAIFWVTRRRGQTYNYPSSIGPGINAVRESRRPPEVKIHGENPNDFVVSSGSPPTPWQTPTFNVDAHQTPTVIGPTPVSPTSRRPKYSLAFTAPREPRFEDIEMRIQKPSLFRSMTGMFRNERHPSEHALQVTVTTMITDDVEAGNEVKLSNEESESQVDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V641</accession>
    <name>A0ABQ8V641_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calmodulin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_846222</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4476259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="150" mass="16850" checksum="BC5F7DC1212141AD" modified="2025-10-08" version="1">MASDQLSEEQINEFKEAFSLFDKDGDGTITTLELGTVMRSLGQNPTDAELQDMINEVDVDGDGTINFDEFLSMMKKKFKDTDNEEEIRQAFQVFDKDGNGMISAKELKAVMESLGENLSDKEVDAMMLEADQDGDGNINYEEFVDMMLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6I1</accession>
    <name>A0ABQ8V6I1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_897187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF9">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="343" mass="38623" checksum="6A7F39F79ED83BEE" modified="2025-10-08" version="1">MADPVEYNQLGSSGLRVSVPIVGAMSYGSPLWGSWVLDEENSLPILKAAWDRGINTIDTANVYSNGESEKIVARFIEKYNIPRHQIVILSKCNGLVAADPGTRTYYNPHMRDWPQYVNQSGLSRAAIFNAVDASLERLKTSYIDLLQIHRFDPKVPVEETMKALHDLVQSGKVRYIGASSMRCWQFARMNEIAEKYGWTKFVSMQNEYSLLYREEEREMNAYCNFNGIGLIPWAPVAGGKLCRPVETNATVRAEEAKSSPSYSPFSDADKTIIGRVEEIAKKKGWTMTQVALAWVNMKVTSPIVGMSSVQRVEENVITGLVLDGKEVEYLEEPYEPKRVRGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6L4</accession>
    <name>A0ABQ8V6L4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycolipid transfer protein domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_779055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="204" mass="22484" checksum="F1B556625072C88D" modified="2025-10-08" version="1">MAPYLETVKSFADVPVTDAGVDTLAFLEASQGVLGLFDILGSTAFAAVQSDLKGNIIKVRARYDAAPAHSATLEELVKNEQGEKKRTATEGLMWLLRGLAFTCTALLNAQANENEELSVAFTKGYERTLKQYHNFIVKGIFSVAMKACPYRKDFYAKLASDLDGGPAVTDNIISEELDKWLAALDLIVKRMQVFYEKHGYTKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V740</accession>
    <name>A0ABQ8V740_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_773978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="150" mass="16922" checksum="F1D68B98161E4878" modified="2025-10-08" version="1">MSLETGRYIIKNGENIVGRALAEDLSLRPKRVILTDHDSTVVIHFMQWAVEKLGNNLDTFYTLISNGSPTAHIEHNVYALVIDRELATKWYIRPIPQHGETTITGTDRKGGWVAPGKVGEQIEYKPLIVAPSEPPRYPTNQVFHFTKAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V786</accession>
    <name>A0ABQ8V786_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_801089</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="237"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4473227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="338" mass="37932" checksum="3BF5B627805F1F85" modified="2025-10-08" version="1">MAESQFALPSPPFDSISKVQYSPTNPNQLLVSSWDTTVKLYDVGDDASGSKTSEQKCKFDHRAAVLACCFSDAEHGFSGGLDNTVRYLDFESEKTNVVGSHSDAVSSMVYAKDLNALISASWDRTIRLFDPRAPTPEQSSHENPERIYHIDLVNNTLVVAMASRLFHIYDIRNMQEPSQRRESSLKYMTRSLACMANGEGYATASVEGRIAVEYFDPSPEAQEKKYAFKCHRQTIDGVDHVWPVNALAFHPIYNTFASAGSDGTVSVWDHKIKKRLRQYHKFNNPISSVAFNCDGTKLAIASCYTWDEGDQGARVERERPQVWIKTVGPEVKPKDWQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7R7</accession>
    <name>A0ABQ8V7R7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histone deacetylase interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_844667</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="6">
        <location>
            <begin position="552"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="525"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="866"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="918"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4477975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1305" mass="146206" checksum="65F1A7F89C997B69" modified="2025-10-08" version="1">MSAFSTRENSPARPASHLALGNPTVMPRTPKALTPRPQAEQNIIPGPSSAQSFEMSRPLNVTDALSYLDDVKHQFAEKPEVYNRFLDIMKDFKSQQIDTPGVIGRVSKLFHGNPPLIQGFNTFLPVGYRIDVSGDPLDPNTITVTTPQGTTTQTTTQSSTAHVPRTISHPPRDIPGFGPNLAQSFPFPGINTPNGASPLTPLNPISRSMTPQQPFHIPHQSLIFDLPFSPGIQQTQTTAAASLLGNLNNKNPIEKQPQGEEFNHAIQYLNKIKNRYSDDANTYKQFLDILQAYQKEQRHLQDSQVYVQVQVLFKDAPDLLAEFKDFLPEITGGIPHPGNAIMPPPSGAGPSSQPWNNSNDSAPVSPEKVSKKPVAPGVKRKKRVIEKEPTPAPPSKPAPSRAKKPKIAHKGDPGSPSFSPFPLPKSPQLPTSHSAPSLPPIQHSQVPSTPSFVPAPPIPTTPSKLKFFDRLKKTLENREIYEEFLKLLGLYSKDIIDVKTLISRAAVFLGEGDLMDEFKEVLGYDPKQDDVENGPPGSIRTGPPEALAAQPSDDGQGPSYRKLPWSEVRLACSGRDELCRSVLNDGWVSHPTWASEEAGFLTLKKNSFEDALHKSEEERHEYHVHLEAMTRTIALLEPLNERIEAMTADERSLYRLPPGLGGLSKGIYTRIIKKVYGRDNGAEIIQALQECPGVAIPVVLSRLKQKDDEWRRAHREWSRTWREVDCKNFYKSLDHQGISFKQNDKKAITAKHFVADIESIQARQHEELDDLNTRFQSGDEKGKQKAWTSPFARGSLPAQLEFQIQDTAVLHDCLKLVYSFLDRSQGQYSVLERRSVEKFLRVFVPTLLMYPVTEFNLACEPHHEGVGTNTGGADDLNGMTEGNAMDSSAGSKGGRKVSGQSNGIVAGDLRKKLLKTAKERRRKREERGGSTSAAVSRAGSPPFLESHRSPLVPASRQEEDPVATVHEDIWIRESSAAGATTMDFINSEESRNGNFERPFFANTTFYTLFRLLQLLYSRLLMCKEIGQDLATRKHAQLLSNPVAVQLGLDDPNGPATVLAQAMEQLNGGTNVVYMYLLDACEKVFAGDLDQVSFEEHMRWFFGNKAYHLFTLDKLIIALVKQVQTITSDAKCQELWSLLQSAQVSESITNQDVIRYRREAETNVGQDGNLYKIQWERELKIMRIHLMRQEDASVNSFRKPHSRWRAYVDSWILRYPTEWMPSQSKEAGPHPVFLRRTRQLSENRTVTMEGEVKIGISLPEYKIVYERGSEETVTVRQKDSAMLEERAHSRREQGKLFIRRVILKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8G8</accession>
    <name>A0ABQ8V8G8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">XLF-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_843244</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.210.10">
        <property type="entry name" value="DNA double-strand break repair and VJ recombination XRCC4, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015381">
        <property type="entry name" value="XLF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038051">
        <property type="entry name" value="XRCC4-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09302">
        <property type="entry name" value="XLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XLF-like N-terminal" evidence="6">
        <location>
            <begin position="17"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="196"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4479914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="39406" checksum="BE2F44FA3B63FAD1" modified="2025-10-08" version="1">MEQLSEEHSKLLSSKEWLVKVDSHKSTPYLFKFHSSKIDQSCLVMITDTKSVWTEVISNSQIARRWRACNKDFAFEIDCEGFKWTWETCFIGYRNSAEIISKHLVLPLISVSHTALSVGKPVGEMVESELEKAIDAVGRAARRSFDTHVKNAISKPRMNSSIQRMSALFNLVDHLPPISFTNEEIKLQITYPPHPRVQVVRSPSPTKARSVSPGLMEQPNLAKTPPKPLSPSFVLREPSDNPLKHHSAEDSATESDDDEPGPKVIPVAAASTSSIPPQRDFRHQSSSPARLIPKAPPSSDSSPVRPATKKKKKETSSSEDSEEERRKRVAKLKSGTAGTRGGVRQPLKRGGKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V998</accession>
    <name>A0ABQ8V998_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DWNN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_841452</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014891">
        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF0">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01180">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="11">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="10">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="521"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="442"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4481807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="558" mass="62296" checksum="012DF2D24750C1BD" modified="2025-10-08" version="1">MASSVFYRFNSRKDESRVAFDGTGISVFDLKRDIILAHNLAKANDFDLKVIDGDSKEELLDDGAIIPRSSFVIIKRVPAARPGKGKASMYVAGTANMIPTSESVQRGSAFVHRGAMSKRFDGRDDSQTKFGMPSNLATPVKTNVANDDETAAMAAMFQAQSANWEEAQEKMSHATRIYNNQRGPPRPGKPGPSTYQPPDRPLPASYVCYRCGQKGHWIKDCPTNSDREFDHKPRIKRTTGIPRSMLKAVENINNGELGQGVMVTPEGGYVVAQPDLASWQKQVSRTNKVLTAAEVRDRNTPSDLTLVCPIDNKLFRDAVETPCCGTSYCEDCIQTHLLERDFICPNPNCGKKIASLDKLSPNHEQRRRVSDYIQKAIEDSRREAADSDEMEDGTKETINLEQDFYSDQQPGMDVQQLIPMLQAQISQISVALQNPSLPPRVRQQTEVQQEQLKIQLQQAQTISVALAAATEFQQQQQAQQMQMQNIQQQQGSMGGSMGYNNNMYPSQGGPSQVVQDSAYQRLPVNNRRRNLKRDRPSDFLEIGNGANENDAKVARYWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9X7</accession>
    <name>A0ABQ8V9X7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUEL-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4483128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22583" checksum="3D7D903140447A67" modified="2025-10-08" version="1">MTTVDAIASSPDKACKVLHNGFNRHNKPCEYYAGSQVVKGTCQDKRHRVFKLTCVPNALKGSVDNASAASATLAATSIRASGRVGFCRRFWGPPPVQHRLLRRVHPLPVTQQTDRVEGLQLGTGCEQVGHSLLPLLRLVQNFIMFLGFNWVKRKDGYVQFKGGGAWYLTLTGHGINFLCLLLGLVGLDSEDDRIILDMIHHSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAS5</accession>
    <name>A0ABQ8VAS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="23503" checksum="CD9176F2ABEFC53E" modified="2025-10-08" version="1">MESVEDGMHRHRAMKMLETLQSLIETETINQRNLEDEEILSTVRDSENKEKKLASLVVKGLLYCQDQASQDMQVLIGDSQFPAAEVVKKDLILDVAIQVEITRALEMRSVVSRQLLDPDIVDLNWLAEVAKITLGDSTTIDDKQRILQRLQTASAITLSNALEWLADVIRYKAQYQLKSDASEHELYVLLPPFNAKNKKRPTSLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB25</accession>
    <name>A0ABQ8VB25_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_839253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="29258" checksum="0040A5344135C8DB" modified="2025-10-08" version="1">MPVADINSNIATSRFIGTSVSWSDISVSSQPLFSTTVATLPTSSTPTVIQDSTNSPLKVTFSVVPTSLNSDPSTSSSSSLTSSLSIPPGNSKSHTGAILSGAISGRALAIIIIIALRLVYRLKRKVRQLSLGTYSNHDPNGPMPGIALDISARAGEGVGLIPANDGADARPGTVTPYPLKYQSLTQTNTSLATQSPPESPPERKTILDGEFSPVAATSGARSETSAEESTELTTRDVFVHQDGGRVEIETSTQGKLEGGEQDPDEIPPTYESLFDTVDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBR8</accession>
    <name>A0ABQ8VBR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_418330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="115" mass="13287" checksum="FDD4CD228A24C243" modified="2025-10-08" version="1">MPAERINREDVAYKYGHHNSMALDPRLQCMQKETNGDYYLKGEARLPLSSLLRAAARRALIFCSKTEHTVQWLTFTHSADKIQWDINIESSSSNWILTLQSLHTRGMGVWLPKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBZ7</accession>
    <name>A0ABQ8VBZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_838104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="350" mass="37704" checksum="4222A4E1B8458E9C" modified="2025-10-08" version="1">MVLQDYIPKTSSTVMESSVNTLYMERPSATNLACPPKLRPLIIPEQGTVAIGLLTPVEETPDDSEASSSTIIRPLPVPSRRNNPNRPRAQSTATQSAVSRLFPKSPTTRRDVIQVIPDPPAVVASTTIERLVGSDSEAPEMFLNDHQHLPSKHTFRSGGPNLGSRKGRNLTDLPPIDAGTVSTGRISVSKTPHQPSHHFTRSERPFLSRARANTSVALPGHQIQNRYVSPTATSSTTASLYSANVNTSDTQSPKIPITKVKALPSPPVVLEKIEGNRFHVMSKDKGKGKALDFAGQSDPQNDYQGNTGYGLLTPPDSAKSSCPPVSTELALSGFRGARPRGPRTRRSTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCM8</accession>
    <name>A0ABQ8VCM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_412126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4487505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="43916" checksum="9EC38F5F5FE92DBA" modified="2025-10-08" version="1">MFFSDNISGPRGLMLFHRFRSAGTSHLLAPRYVPEHRSPYYHLCLPHLPHLYPQNSQLAQSSFTAGLFLQDKDHPSNCYILSVGHPFSSEFHSHVINDERKDIKIGWPDASLSLGHCDQYLKLANLRIPKLEPEMKLLYAQTIEFKGGNEHQQNLFHSRKKRYEFLAATIELMKLDILEISNRKISLEKLRITPSDTEIGHVFMACFGFVNGTSVSTSKSDSILLPQHIPLTPSASQPPSPHPNQQFIDVSLIKITNQLLIPPPSIPQHFSSIQELRPGQKIVLDCMAVQPLQIGKIGLLESFFGLPDPVCTTRNSTEISDAKYFIHEYCVSKPRFAVPGASGAIVRTSAEGAATGMVVGIFEGPGIELSIILPLTRLLDRVESTCGMKLELIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCY2</accession>
    <name>A0ABQ8VCY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_511328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="122" mass="13912" checksum="64676E1438BE0F43" modified="2025-10-08" version="1">MLNIASSHLHVFLPRSYRIVPRESTLTKPAWTPETIVLSVNDSPVRAGCSERSRSIWRCDNVEHVSGLLNNAYAVEVCITTCWNEQERTHRSPRLKAVCFIGIVRTRYSPPLHEIVAIRSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF85</accession>
    <name>A0ABQ8VF85_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_836878</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF28">
        <property type="entry name" value="VERY-LONG-CHAIN ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="169"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4487480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="326" mass="36757" checksum="C9554C3FF794F7D4" modified="2025-10-08" version="1">MSSSKITISINSSSKKPPSFARNVSFPITIQASPEETVGHVKRKIQAKIPKFHPSRQRLTLKPTGNTKSPSLADDSKLQDALAGLAPGSSTLELEVKDLGPQLGWKTVFVVEYAGPLLIHPFFYYLPRLFYGTDVTHSDLQWLVFTMIEAHFAKRILETLFVHRFSHGTMPFFNIFKNSGHYHILSGLFLAYDLYRPSFSVSSPYIKNTWRNDPQVLWVCVGLWAFFELSNLLTHLHLRSLRPSGTKKRAIPTGYGFGLVSCPNYLFETLGWGVVCAMTGSWAAYLFTTVGTGQMLLWALKKHAAYKKEFGKAYPRGRKSMIPFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFE6</accession>
    <name>A0ABQ8VFE6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_840099</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4483984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="549" mass="62362" checksum="8DB98298BE75AAD7" modified="2025-10-08" version="1">MFALTVKNITAFILFPPLCILLEFVYRYFSRSLKFLRGPPRPSLLFGNELELTVQEEVGVLETKWFNEYGLAFRTSSCFGEDALMIADPQALRYITMTSAYGYPKSTDSAQITTLQFGPGILSVEGEIHSRHRKVLNPAFSVSQLRQFLNLFQRSSVRLADKLQYEELGNDGKVVNVTHWLPRATLDIIGESAFDYKFGALDGEANELSEIFKHMFADARLYPQKRTLLYRAFRRSVNTPIANLLLKFPGKQDKKMMEFSVASKRLAKSLFDSALKETKLEGDTKSSKDVLSVLVRSNVAEDSKKALSEDEVLSQMATLILAGHETTASTMSWLLYEITRNPKDQERLYQEISNTRERVGPGINLTANDYDSMPFFNAVIKEGLRLHPIVPNISREAGSDDNIPLQYPVTSESGERLSHVSVAKGQRISINIAMYNRLTQVWGDDANRWRPERFMNEKKKDITVGVYSNLMTFGSGVRACIGWRFALMELQAILFSLLERFQFFPPPPDGSFRGLDDIQRVPAGLMIPMKRGNWRQGVQMPLLVKLRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFN0</accession>
    <name>A0ABQ8VFN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_867148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="124"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="124"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4492448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="535" mass="59429" checksum="A2DC29067E2A1C00" modified="2025-10-08" version="1">MPALRTRDTQSRPLEVTTDAPQPPTLTIISPTPRAFTFPFTHNLSSDSPYSTPSNSPFEPDLNSLAISSASSCITPPPRTLSPTSSFTSVSPSPTSNTSTSHLSQKSLGNDVERRPKKGDEDYVKRPENAFILFRRKCCEDHQAAEEETSPSRLTKKQRQADLSKTISQQWKSLTSEERKYWEELAKEKKKEHAHMHPGYVYRPQRVRDKDGKARNKKRKPKVTAAALEASPNKATGSMSFVVAPPCQHGRSASAPTPPPMSYQSIQLPNLYSSSPSCPNSPSLLPMISRRTTHSGNQEDIMADFDFMPNHEHLLAPAFGTEQPNLQSSEFLRNIFNMSLNEAPLTVSTDTSLLLPAHQMISPASSMGSSSSGPSSPTTGPFTPTHPIHSHNAFELSNIPNSACVPELDMQLQMPNVGFSANYWPMQSVWRDESNMEMMHNDFDLNSIPSIQMGGPKYVDETNTYGASPEVMDLGEYSQEYRQDYSNEYMAEYQQDYVQLGHNVSTAVSYVNGYVSTTRNFRKFVPASSKDNKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFZ1</accession>
    <name>A0ABQ8VFZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_765214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1042" mass="120087" checksum="DB841338026E8950" modified="2025-10-08" version="1">MEEDEKDWAPHGSKTMFMIDLLDKQPRQRLSDPQLKSILWVMRECGCKDVPTFTQVRNKQTEIAHELDIPSEHHTSSLGNHFYMNHPAKLFALDWANPLVRPHMQLYPEVSGPIRESWQAAKWTTEVDLDELSPMWADWKYTPHRQYYVKELAQLEDSTYVVPLRWITVNGEEYMDALPAHYIQTVRQIVWLFYKKYLIIWNREMNLRFRILTLCSAYPLNICIEISLMFKSTSLNDMYQITDGSPIFTMPHALRVKAKSKPLFRMRIMPWSDDVSGNVSKQYNAHTNIYAVSLNLPHKKLSQEFFVRFCSTSANASSSEQFTALAKDVAEDVWHEAYDCELETDILFQIIPHLLPADNPQQAESASHVGGKGNLPCRHDMIGGTSIQRESDTGYEAFFSVSQHPGLARTVSTTVQIIRQQLWLACLGDNDGLASSYSQTGVKDKLSQYWITQLCAQASEKQRKLFFDPVLRDPRLADKNIKGDERKAIKLSLKQTVQHELWEWLITQPEENYNKLDPNDGLDPHRDTPVEVLHTFQLGADKYAWYDTNKVWDKAKDELFGLRLQSSSVDGLSIPPIRARYIMQYKNSLIGKHFKTLQQVGIFHLHDLSSQLLFDIWKATGELGAHLWVTEIRNLELYLEDLKILIGNLLDAWATYDPNRILVKMKLHVLTHLPDDVRRFGLVILYSTELFECWNAIFRMCSVLSNHLSPSHDIAMTLAEMEVFKHLVSGGWWKNKNGQMIQAGAKIRQYLVKSSELQRRLGWVSPSQSKPDYVLKPIPRSCHPRTQDAITWDEIYTSFGISEPQPPSETWDLCKSIVAQSRDVCCKGSWVFFEHNNKTLSGRILELLVRSGRRNTSAICIINLFDILGTRDTRFGMPILQPPAHICVLLIPAEDVLFIFNAQHDCVTGGCHISTINSFEVQERIETNIPKKVVVHSSSQRYFVNMHALHNSNLLRDTLPRFLTEPIPYFQNRQQKHQQLAAHMRVIGPAKPAETQAKSKETRRRNKELREGQGIQQLPAVTEEDNDVEEEHDDADMNMDTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH67</accession>
    <name>A0ABQ8VH67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Urea transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_768438</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF2">
        <property type="entry name" value="SOLUTE SYMPORTER FAMILY TRANSPORTER (AFU_ORTHOLOGUE AFUA_6G03200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="590"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="620"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4486883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="663" mass="71235" checksum="959DD9E240C8A525" modified="2025-10-08" version="1">MAVSDSPPPLPQAVGYAVVLGLGIVFALAMNVTTWIQARFSKYKPNSASEFSAASRSLKTGLVVAGIVSSWTWSLTLLQSATQSYEMGVSGGWWYAVGGTLQIAIFSVIASKVKMNANRATTFPEVAYARFGTAGHLSFLWCGLICNAIVSSCILLGGGAVVSTLTGMNEYAALFLIPMGVAVYVATGGLRATFISDATHTFFLLAILLYFCFEVFCVSDVIGSPRKLLELLEAVAKTTPVDGNYQGSYLTFRSRPGAIFSVQVLTSCFVQGFGLVMCDQGYWSRAIASNPATTARAYFLGGFAWFSIPFACGTALGLTARALETQPDFPVLSSTDVSAGLAAVEAVNYVLGTAGSVLMLLLIFLSVTSALSGEMIATSTLLSYDVYRHYFRPRATSKHIVDASRIFIVFWGVFAGSLASVFKLAGITLGWLFYFLGVATASGVFPIALTFLWKDLNREGAVAGSILGMFLALIVWLATARAVGGEITVDTLSNQWASFAGGATAIISGGVLSITLSLLRPANFDWEKTRNLTVVKEVEIDEDRDGSSLSSNGVPSIVDIESLTRSTNDAAGIRDAKLDMTALEKTFKRYTLIFGFLALIITIIIPVPLGAAPYVFSPRFFAGIVGFMFIWLLFAAFLVVILPILESRRALWKIILRVVERRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH74</accession>
    <name>A0ABQ8VH74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase lambda</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_834163</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="14">
        <location>
            <begin position="331"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="16"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="551"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4491076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="950" mass="106876" checksum="6B7F3F12AB7E2869" modified="2025-10-08" version="1">MPTMNARIFFKEQEKRMNFSDDDMDDSYVARMTGENEHSASEKKLDNGYTQNVPYASQTRGHKRKTGRSTPVRSSPRIKRSKTSLASANPQVDAQDGDSDNDDALDFSFPGDVTPNRHHSDSSNQSFHRDPDSVARVKVEPTIIIDGPLATRSSRHTRLPSKSFSDNSSDASTAPSSPIEEARSLSLVPATNGKAPEKEKSMLEIILEAKHSTHRRSVKKLVPLAQLQIKPKHQLNSVEETSIIDNYSSSEALTSPDIACSSSIAKVGSKSAELTKGSISKSRLTAAPKLAAKLSATTKAKGKGKTTVPSPKLTPYEFVCQIQHAQVNKAGKVQFLEGTRIFYCGMDINSKLSGDSTQKRMMIILRHGGSVVPRYQTDQITHIVVDKNLGQNSLLKATGLEKLTNVPDHIPILTWQWVVDMMDMNPFLNNGKVHKIRQVSSLFEYGAYPNRLPPVSISATSKYFEQKRAPQQGDEDRDFSRISEFSANDIKPEVGSSRHEPLESKHVQNTMIKLASTRLPLDFQIQKPVNQEIVDPLVEFYLQRKANVQHRNGFDSNTDDSDLEPNHRQAGPKPQRDWLCKKPNQNAKPCPNEDIIRKLEELQELYKVKPTEDDHWRVYSYSKSIRALRAHPKRIKSLEDAEKIQGVGKKTAQKIMEIIETGDLQRIAYERTEDVKVISLFTKIYGVGIQTATMWYARGCRTIEDLCNGVGDVTLNEGQKIGIEFYDDLNSRMPREEAKAIFELIKPIALRLDPTLFVEIMGSYRRGKTDCGDIDILITRCPDDGLTHEGVLHKLLERLHTAGILTEDLALPDYSKPLEAVYHGICRLPNVPGARRRRIDFLTVPYSSKGGALLYYTGDDMFNRSMRLLANRMGYSLNQRGLYAGVVRDPRNRTVKLNNGNLIASETEEQIFKALGVPWREPHERVTYYQDIVKAEEEKSKKTTTMITKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHH3</accession>
    <name>A0ABQ8VHH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_866845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="159" mass="18329" checksum="C2B6279A1F8178DC" modified="2025-10-08" version="1">MAKTAEATFEVDKEGDLSQTNWRRKHMLELGKRERRRRGGDVNRRPRKIEQIVLVGPSAGETRVLLATGLRETELREEGAFYAGRSGRRCRGGRDTKERKKENVRWVGGSAIFGPLPGHVTRRLFCDFSRKFDIDNRTEVVHLTGMKLIERYTDNDVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHJ6</accession>
    <name>A0ABQ8VHJ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_895397</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="340" mass="38153" checksum="2E6CDA17DD768B76" modified="2025-10-08" version="1">MRVLMESWIRFLQEDIVQALEKLDPNAPKFQRDSWVRPEGGMGQSCVFAAPTASEGQKEFILEKAGVNISIVHGTLPPPAIKQMRADHTSMPLPEDAPGGLPFFAAGISLVIHPKNPHAPTCHANYRYFEITDPASASAGAEVAPKTLAWWFGGGSDLTPSYLYPSDATHFHQTHKSACDAFSPSFYPALKKWCDEYFYIPHRSESRGIGGIFFDDLHAGPHARLPDNPRTLDSIFVFVKSLGAAFVPAYIPIVEQRAKTPYTDEQRRWQLIRRGRYVEFNLVVDRGTKFGLMTPGARVESILMSLPETARWEYMSEMGADEETEEGKLIRVLKEPKEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHM8</accession>
    <name>A0ABQ8VHM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thaumatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_794303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045160654" evidence="1">
        <location>
            <begin position="20"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="254" mass="26929" checksum="BCE09978DFD1474B" modified="2025-10-08" version="1">MKNSIIISALFSTFVAVSARMFTVKNNCKYTVWPAIFTDMNVGTDKPSMPTGWEAAPGNTSTFTVPDDWQSGRIWGRTDCDFSKPNASSCATGGCNGGLLCDEHSGTGVPPVTVAEWTLGKNGSPDNYDVSMVDGFNIPMSVVPTAGCQAIDCNTDLNPNCPAQLQLKDASGTVVGCKSACDANLDGDPQNSPNCCSGSHNVPATCPPSGVQFYDYFKNGCKNAYAYAYDESSKTALWTCDSTKNADYAVTFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ60</accession>
    <name>A0ABQ8VJ60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013240">
        <property type="entry name" value="DNA-dir_RNA_pol1_su_RPA34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08208">
        <property type="entry name" value="RNA_polI_A34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="296" mass="32880" checksum="FA040E998B677DB4" modified="2025-10-08" version="1">MSESDSSSSSLPSEAYVKSKPKTSIRSKTKKISSAKPTPEDDPTWAYQPPEGIALVENTEIHDEWDWDTFKKDPELELWVIRVPNGVKPKHLENMTISLPDSSSNHRNTKVGVLNRKQESYDVWDVCSSSTSGSDDIGGVELGRLDEESTAGGGEEMRGLSCLLPRKKKHGELYIAPRPITRHLLISAQIPKPSSSEDYLMPTQNLPRFSYPQELLKHRFVAFGSTKVAVDHDDETGSVHGNGAGDDGDVEMEDVHLKSEKAKKSTEKKLLKQTKKRKTAEGAVMPSPKKQKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ83</accession>
    <name>A0ABQ8VJ83_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-reducing end alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_867196</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055235">
        <property type="entry name" value="ASD1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051563">
        <property type="entry name" value="Glycosyl_Hydrolase_51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776:SF0">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22848">
        <property type="entry name" value="ASD1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047521684" description="non-reducing end alpha-L-arabinofuranosidase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase C-terminal" evidence="9">
        <location>
            <begin position="452"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4492504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="641" mass="68737" checksum="0DDFBF2D9B8D898C" modified="2025-10-08" version="1">MVLRRTLAVMLAAAAAVNASTFDVTFTTAGHNVPSTLYGLMYEDINHSGDGGLYAELIQNRAFQQVTPGTSAALTAWAALGSAKISVVASSSPVSSALPNALSFAVPSGTTSTVGFTNSGYFGIPVTAGWTYTGSFYYRTPTPPSTKVSGSFTADLRSTSGTVFTSTTVPFTTSSTWQQATFTFTASSTQSAVTNLFALSVGGSTVAGLTMEFTLISLFPPTFNGRTNGFRMDLSETLLDMKPAFFRFPGGNNLEGETAADRWAWENTVGDLVDRPGRVGDWGYINTDGLGLYEYLQWIEDMDMQPIMAVYAGYSLNGASVASNDMQTYITEAINQINFVIGDASTNAQAAIRSSMGHPDPFTLNYIEIGNEDFFSPTTYADYRWADLYNALHAEFPQLHYIATSATSGNVPSLSPAPTYWDLHIYSNPNFFVNGAYNFDILSRNGLQFFQGEYATTTENSGAALTYPFIDGSIAEAAYMAGFDRNSDIVFAASYAPLLNHVSSTQWTPDLITFSPNTVIRSTSYYVQQLYSLYKGDFYLTSTTNTASSPVQWSVTRDTSAGQYFLKVINTATSANTVVFTLPFTPSHTTGTGTILTAASGTQNTPTNPNAAVPSSFSFTAGKTITYNAPGLSLSVLVVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJM1</accession>
    <name>A0ABQ8VJM1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_951206</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00064">
        <property type="entry name" value="FU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.220.10">
        <property type="entry name" value="Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043601">
        <property type="entry name" value="Rspo_Fu-CRD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001368">
        <property type="entry name" value="TNFR/NGFR_Cys_rich_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15332">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15332:SF175">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15913">
        <property type="entry name" value="Furin-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00652">
        <property type="entry name" value="TNFR_NGFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4493256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="779" mass="80440" checksum="4FB08E48D67C1B0C" modified="2025-10-08" version="1">MTISVSGAQTSALLLPGQYTTTTDPELLHALLTSSSASLSPSTGFNSSSVSLPLSVALELGLAIYSNTLSGGPAGFSSLLHSPVGNSSTSLSAQSLTLSSNIWAAINVGSRNCVVFWDSVPDFSQLAVSGSLCLVVMQSSACEPACSSNGICTSSGTCSCAAGFTGASCESCESGFFGLSCQACSSGCLDCDDGISGTGKCLAFNITNAPSSCNCLNGECGSSGECSCNAGWTTADNGTACAKCASGFFLTSTGDCKICEIGCSACADITGDCQTCKSGFTQDANDKTKCDVEPTTTSSGTVCPDGSFSSGTTCSTCSPSCQTCNGATSNDCIICASGSCITADSNGVCEGTGLIADNDKKECDTCGAKCTSCGISGFTTASTVNQLQCTGCLPGLFLSNGSCVGSCPAGTFISSQANTTCSVCDSSCSTCAGSSTFCLTCANGELASNGQCVSTCPANTIAANSTKTCLNCHPDCVSCSGTAFNQLLNQGRCLPVCGKSQFFDSTSGSCQACDSSCSSCSGSGSSNCLSCSSSSQVLKGGSCISANCNGTADVVTGLGVCLSDLVVPTVVTQTSSKHLQWWEILLMALGCAFIFLAVIWCWRRRARKQRAKRPKAFAQAKNIDQSTSWRWRLVRFGEKLFGHRASKRVYPEPTPDANPGLDSEALKLMKLRNAEEARHNQETEKLMLISDYQYPPEKRSNHLHTVDSAANRLSGPSLYSQVTGVPRNGPEARQPVKKDLITSRWVQACPLYLRHGKGPSSLLVHTITTFQAVLVVLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJW1</accession>
    <name>A0ABQ8VJW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_261759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="156" mass="16917" checksum="1F4CCD0F0C0B7B89" modified="2025-10-08" version="1">MLALQHPYLANAIFAFTCTLGFVQVFMGLFMSGSLLALDASGSATTEGYTKFVPIAVAWESVAIATDMTVIRTGFRQTDWMVYNLILVAIECAFPVTLFTIGHITGVLRRGHDGTVRNMGGNGPQVRVDVTREEDYGMESMSNTGRDADLKPIASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKB7</accession>
    <name>A0ABQ8VKB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_824955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="358" mass="38561" checksum="215F309D9DB9B0FA" modified="2025-10-08" version="1">MRIGPEETGSFLLFFHCQELVFVYTKPAFQLNVSGAHIKTSSDDIMKCSSAASALILASLSISAFDTYAAPVSIFGQNMPSVPSTPSTPNPVPFPPSLRREEITNSPRMLAEDTSAPEALEIRHFTNRERYPRANDADSKGLKVDEDEPSRSSTKSSKKSRVKDAPEAPAQFADPQTKESSRKSSKLKKTEDAHGGKPTNTHRHKKTHKSGPPVVAETINESPIENSLDIQSEELSSPAPVIRKRPKKLKPSAEKNDDESLPFGKSSKKPSYLTLSATSQRTSRKPKPIPPKPKTPNSTDGYFYAQNTTAAFNSASSSSATNANAFAVNDGNFGGGNVAGIGKPPEGVKTTSQGLFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL68</accession>
    <name>A0ABQ8VL68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_762377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="39663" checksum="A270A6A47A799848" modified="2025-10-08" version="1">MFIEALLGTRAQRLFMATQAIVVLVMVGITFRMVDEHVSFSTSGYKTLPCYLALFALAEVFEMFMAADALRLRNIIQLVGILLFHLALIVSAALQVHQTRDALINGSVDCSDPDATNYLINCDVPGSLWRKIEPFLIVTPCIIAASWLIMMFWIKQLYGEFGWAIFHIVGANPKTKTMYQYYQVEICLLKFDFFFFTGVTMQLLIVVLSKNSAEFGITIAAIPIVLGLLMGAALAVQREIKWLMTISLVMMLAAETYLYKLVRFYEPSSTSQYNTTRATLTVFTIVAFLLLFGTFVVGLRCFSDFDRGLLPSKVHGQSYKPVSTKVDLFNNGNMSQRQSSYNGGSVLAPRISIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLA8</accession>
    <name>A0ABQ8VLA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_917733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF25">
        <property type="entry name" value="MICROBODY (PEROXISOME) PROLIFERATION PROTEIN PEROXIN 11C (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="307" mass="34803" checksum="3FC2E7436A41A31C" modified="2025-10-08" version="1">MSYTKPSTMDKVADTILGCFSAFTPSELTDHLVRYLGTWSGSDKLFAIIEYTLKLLVPLLNKRARLRNKAYSRQVTTSSAAARVSKLAGTISDSRTLWRFWGLLTIIKWMVSLEHNAQPTRKLLNIERLQGWSMVGYYPLEHLSYLVSHDILPSRSTVDLSPFLTKKSRLELNAGKLSLWSVRCWAFYVALQFAHLREDRKLLRAKYHALRKAGLKPAEMQEIQKRWHAYWSDLLVNLINFPLALHWSTGSTLIKHDSVVALLNLIVAIMSFRSGWIATALPSPPSVAETTDNVVEPIAENVTGYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLY4</accession>
    <name>A0ABQ8VLY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_759595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="422" mass="46321" checksum="FF79F60864C71629" modified="2025-10-08" version="1">MPLSGATQVLIVGAGPNGLACAITLATLGIKATVVDERSERPYGAKGCLIHARTMEVLKTIGISDNLKDIGIQSKGIVFFGAANPILNVDIAGLSESATEFPYILLTPQSEAERVFEEFLIDRGVEVIRNRKVIGFRESSEEGLRVYLEDGSSVIASYVVGADGARSTVRSLAGIPFKDPSSNVMYDENPSSASFMLFTLADVVLNIHSSIHIPRDAISWHLNGRIMFCPLELPEKLRHFDAPGSSFWRIAIAIPPKSATIPPRHPDQVYLQNEIDIRKPWKESVHLDHLHTAATYRVRSAVAETFFKSVGNGKVLLVGDSAHVHSPSGGQGMNLGICDAVALGRAIAQHIESGDDAIFIDYSSRRKEIAMQVIQATKRMTEIINIPNGWRRRIASILMYAANWITPIRRKIAWRLSGLTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLZ2</accession>
    <name>A0ABQ8VLZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_822235</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="468" mass="51398" checksum="0D4E2867012A2F13" modified="2025-10-08" version="1">MQLTADCNLYSTASKGMFKFGFDLDDADIDNDIDSFLQQADDLPGVRTSPRKDFGKRGQENSESIVSGEDGRFVELTMEHLLDALPTQLSYSPLEIPLSSSSTATPSAFSEPNLASGSQVHYLARRDLFDARFQVISEDSGDPNFVAEAENTEEKTERIAASVDPRLQFLDTPSDLVPGVYEGGMKTWECSLDLVDYLHASLKDGDLEGKRVLELGCGTGIPSLYLLQKIFSLPSTESVLERSAIHLQDYNPSALELVTFPNVLLTWYMSPASDTFLSSQASSPDAETDEILEYPAKYPTNAGELIITPALKDAFKQSLEKYNVELRFLGGSWKSFENAIGTGTHSRDSQTQDASEGSLGGYDILLTSETIYRTESFPELIHAMWQSTHPSTSSSCPSSKLSQLTISEPRPPRILVAAKVFYFGVGGGVDEFAEAVRRWNGASGVKTEVTTVWEKNVGVGRRIIQVVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM26</accession>
    <name>A0ABQ8VM26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocation protein SEC62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_917485</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004728">
        <property type="entry name" value="Sec62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011553">
        <property type="entry name" value="Sec62_asco"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00869">
        <property type="entry name" value="sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443:SF9">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03839">
        <property type="entry name" value="Sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="218"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4497447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="273" mass="30409" checksum="0A4AA81410DB29E0" modified="2025-10-08" version="1">MSMEQQAKAPPDMKKVAQFLRSGNAGVKVRVGALNGKRIDYFKGKSAVKALLSPAYAKQKNVPKISTEIEAQTVLNAVNAFTFFLRVQRGGPSGSSSSSPKTLQIIQEQKFAQDEYYAWFYDGSQWTTYAGGILMVAIMLGGVMFPLWPPTMRLGVWYLSMGMLGLIGLFFAIAIVRLIFYIMTVIVASPGIWIFPQLFADVGFVESFIPLWEWDVPKKKSKKKKGDKHKDKSSDVEKLKKNGGAFVEEVEDSGNSRPQSRTAKVEEVEDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMC3</accession>
    <name>A0ABQ8VMC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucooligosaccharide oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_759132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046261191" evidence="6">
        <location>
            <begin position="24"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="55"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="498" mass="53654" checksum="561B7D1ECDE10EBB" modified="2025-10-08" version="1">MFNHPSRTTVFWIAVFGLRSVFADLNNDLTGIGVRAVFPGDSNYAGASAAYNLRFVFEPSAVAYPTTPEDVSSIIQAGIDNNLQVVARGGGHSYVANGLGGKNGSLVIDMSGMKNISIDHSSNTAVIGTGNRLGDVALALNAAGRAMPHGTCSYVGIGGHSAFGGYGFTSRQWGLALDTIFAINAVLANGTIVRATEDSYPDLLWALKGAAPSFAITTSIEINTYTAPSYAIVMEYTWSNMDYETAGHSMYSFQNFSLSGPASPFAGELVISAGSEEGQVTFGFTGAWYGEEGSAIPTIQPWLDTMPPPTQTSLIGDGSYIDTVSQLSGTSLNTSQAADSTDTFYAKSIMTPENDPMTLESCTAFMQYLATQGFHSNTNWFVEIELYGGPNSKIREIPNNATAFSGRDTLFTFQLYASSSNSSPPYPEEGFSFLDNMATSITSNMPSTWNYGAYTNYIDDQLENWETLYFNENYPKLQSLKDQLDPQGLFMFPTSIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMY4</accession>
    <name>A0ABQ8VMY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tail specific protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_758645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045319056" description="Tail specific protease domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="650" mass="71753" checksum="650DB9B68CC853AF" modified="2025-10-08" version="1">MFTLQVVASLTVALASYHKAVAAPAPPDPCAAIAGKLFALPADVLACEKSFPFNETLRQNVLTTVSRVFDFYTFENWYLDSPAPFQESTNNIRANLTRINTTQYEASTHYDFNIDLYDFTTQLNDGHTRWFTNCYTNWQNILPAPFINVDINGTQGVYIAPDSVDFINLIGTSYTDLLEDMGFDWQRLSGARITGIEGQDPYDYADFVADTVSGNYLDHGVRVNSVFSSYRISGTDFSQRLGDLAGPTGVKQTSLEVKLVVANSTTEETVTIPFIASFLGVAFTDQASYWENNCAANSDTNGMDLRSSGLTRRLNETPRRRLAKGNIIDKSNDSAIGLPPQFLPTAPQVDGSEDVIKNFILPDNITGVMFVGSFEPDDFDQFQADTVAAISAFQSAGVSRLLIDLTNNGGGFVCLGQFLFQYLAGSNIGYPGFVSTNRANLLAQKIVAADIALGNDDTITFYSADNWAFLNDTEMSASYDYIDPSLPFTVNAVNEPTSQRFHDTCQLSFTQTIPEDPPFPTEHALTTDRKSGNCASTCAMFSTLMNERLQTKIAVFGGKPGENVEFKGMAGNQVLEWADIDTEIKTAGLKDDPLAPPDLLVSGDFRHNWRTAWSWLNESIPIAFLSELPKLRFPFTLETYNNPQNLWVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN21</accession>
    <name>A0ABQ8VN21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_821068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gemin-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794:SF0">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794">
        <property type="entry name" value="GEMIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="42073" checksum="5324E3CE8D8E4AC4" modified="2025-10-08" version="1">MNNLKRKRGDFDDIDDENPSFGKQILPVANLPNTFDGIPGDGMEYLFTVRRDARLLPHVVRVANPFPVEQPSLPPPRSLETTHPSLPSNEWRFLFEIRFRNLRKNIMQFTNSSVSNSKILMPELKDRSAWWDFLAGKPESVWNPTKKPKALKQKKFGRGMRAFHDDATALNYNGVSTHDGEVISQPVGMQSATPAQHDDNKARLESPLPPCKPVIPTPLLLGQIDDRTALHLVMYFTYWINQHLVEDRQPPFPRLTQAHFQWIFALLARVGEYISADDMNLLRNLTRACIALLKVMICERTSNEAHSGDKMIKKELEKQEDNGEEYEGSYSDEQGSSWMIISIVIGIWGQRDLWMDAEDMLNSLSDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN87</accession>
    <name>A0ABQ8VN87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA photolyase, FAD-binding/Cryptochrome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_917232</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="7">
        <location>
            <begin position="66"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="631" mass="71026" checksum="E5FCE8D6E2480B25" modified="2025-10-08" version="1">MPPKRARSVSAGNELSGITKRPRITSFAPRKVATAQNAAAVDADQPMHKLLEAVKNQSKTVKNGDAVVYWMRMADLRISDNHALSLASAQAKKEEIPLIVLFVISPQDYKAHDRGPRRIDFTLRNLAMIRNSLAELNIPLYTSTHNVRKTLPAAVLSLMQDWKCTNIYGNIEYEVDELRRDMEVCALAKSKGVRANFVHNKCIIEPGVVTTKENKAYSVYSPYQRKWISILNDNQDQYLTEYPDPHPNVDGIREDTELSKLFECEVPKFVPGFEMEDNDKQTMATVWPAGEEVALQILNHFLHTKSRTSQMGAANPVAEGAESSDKASRIMKYGQDRDNADRDTTSRLSPYLSAGVISIRECVRATLKLQKSKKVDGSRDTGVGRWIQELAWRDFYTGVLAFFPRVSMGRPYLEKFAAVEWEAHQEAGAGGGDVGKGYNDDDPDPVGQREDAEVLKRWKEGMTGVPVVDAAMRCIRQMGWVHNRFRMITAMYLTKDLMIDWRVGERYFMENLIDGDLASNNGGWQWSASTGVDPCPYFRIFNPYSQSIKVDPTGDFIREFVPELSKLRGPGKVGKVLFEKFSGYITKFMIDLHNPSASVASKLGYPHPIISHEEGRQRALERFKNAGAATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNG5</accession>
    <name>A0ABQ8VNG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_759631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="141"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="537" mass="58067" checksum="D4A735546A95B837" modified="2025-10-08" version="1">MDRVDSSADDSALDDGDTPELSEVAISKHLATSIVASGADTNARRLSSVGQDFNYPLDLHTFPVSHLSERTRRPSVIRADSGTETIATIASSLKDSVPPTRTQTFESTTAILNQIRPLQYEEPPTVTDQVARKQNRRSNIQFAALCWCFALEGWNDGSVGPLLPVIQTYYSVGFSVVSLLFVSNCCGFIIGAGANVWLNERLGFGKVMILGSLFLLATYVIQSPAPPFPALVVSFLFAGFGMSLQGAQANGFVGSLKKNKSAKLMMLHASYGMGAFCSPLVATQFSQARHWSFHYIISAGIAVSNTVILCAVFRFKRQEELLMEIGQEPSEDAFNTTPTSVNLYQQIFNIRVVHLLAVFALIYVGVEVTIGGMPQYGWIVTFIIRERDGGAAAGYISSGFFGGLTLGRLALMYINKRIGEHTVVFIYVLLSIGLELTVWFVPSIIENAVAVSFVGVLLGPLWPILVGHGARVIPAYLFTACMGLITGVGMAGSAALPFITGILASKYGIKSLQPFLVAMMCTMVGLWALIPNTRRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNS6</accession>
    <name>A0ABQ8VNS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_865096</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="612"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="659" mass="72062" checksum="F19A02BD92D42802" modified="2025-10-08" version="1">MSRSRHPSSMRPDFSRSTTTTGDNLLIPDGPVSEETAQLIHDLVHPHHAREATLVDTYTTAEEEEEREYRRRLPWWKRPSPVWLLVLLPITSISMSATLAPKVEIYTDLACAQHKPEIADNHIPSITPYLRTTSAVTITNFSATSHNSAGELPGAIEIPTKKPSNPCKSDPVVQAAVAKLAAGLYQRLMTACMGVLSCITTGWWTSFSDRHGRTAALGISVFGILITDVNFILVYYFSRSLPGGYWFLVLGPLIEGSMGGFTTAIATIHAYLADTTTSASRSRMFSMNLGLLFIGFALGPTLGGLLIRFTQQTIYVFYVGALIHMLYAFMIWFIVPESNSQKKMQRARAKYQEEVEQSQRAREGASILIRGKRLFSFLTPLAVFNPVPMSENSLKPPRRDWSLALIALSYAFTVSVVGSVTYKFQYAASAFDWSSETGNLKLGYWLSLVGAARAFHLAVILPLCIKLFKRKPPKSLAEESEPLISSPSSATSPTSDTRSDSPSRLMEPHSSTFDLGLARVSLSVEILSYLLMGLVTNPLAFTLFGMLGALGGGFSPALQSVALEMYTARGGTESGKLFGALSVVQALSSQIIGPAMYGLVYMKTVAVFPRTIFFVSLASTFISFVFLSFVRLPRSNGAKELTVADTSEERSGQHAGTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPL8</accession>
    <name>A0ABQ8VPL8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_148748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039226">
        <property type="entry name" value="Ski3/TTC37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040962">
        <property type="entry name" value="TPR_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704">
        <property type="entry name" value="SUPERKILLER 3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704:SF7">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18833">
        <property type="entry name" value="TPR_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="665"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="699"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="980"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1186"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1149"/>
            <end position="1176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1423" mass="159085" checksum="9D8D5142B6922608" modified="2025-10-08" version="1">MSSFVKTKLKNARDFLGKKNHAGAKDAALQVLQYEADNYNANVFLGLASLELGEFSEGEQAYKRATELNPDQLLAWQGLSQFYERTKDWEKYSDVLRRLVDMHAKSNDSVKCAETLQKYIDLQRERGTSAQLIDALYLLLPDSALYQALSNLPPPDPTNPTLTTTFLVQTAIYNSLTVIEELITMLEGDEENYLKKELEKRRTRLNAGPPDQIRKEIGREVWGKSRLPFLYNQVLDHPNTDDVLRRQTDSKLLRYKYQYMCSLSNSGNTIATKEEVMKEIEGLISGTVLLHIPDELAWTLFLERKNVAHIDDYGVALLQEFMELFPTHSLTTLLKGYFIYMQIPISEGARDDDNAVEDTDVGYDMVLEAFPSVSTSLIAARIVSEIHLLESDYDTAIQVVESGLRTLANFEQDNGKILSNVRLAFQATLATALVHLYPPKHHRRALQLVDEILLVSPENIAAIMGKGYILEASHEWGKAAENFSKVFELLGTEHDEGLRAQEEYAWCISRNGDVQGGIDSLQNVLHILNGLEGRDHDRARCHWRLGKCLWDLDSEKIIEGYHNFIAALKCDPNYAPAFTCLGIYYSEHLSPPDPARASKCFQKAFELDSREADAAHRLAKGFADEQEWDLVEVVARRTIEGEGGLDGGLQKIEENVAGKYLPTNAWAWKALGVVSLMNRDYIPAINALQVALRAEPEDSLTWLRLGEAYHKSGRQSAALKALQRSQELHDENDWLCSYFVAEVYRQTGQYEDAIDQLEVVLSSKPTELSVLTALAQTHLDFGRAKSSDGFVARAERALVESIRISLKAIAKSTGFRTVIWKTVADALYFLSTKDAFCHLDVVHSVLVDVKSVLGSPSNRIADIIPYQSQDDLHLDSNGILEVAIAAYDHRIELGSPESIAVDSAWFDYSISLRSLAQRLPDGDRKTKVTDQISKALIEAIRITPNNDTYWVALGDFHFSQQPKMAQHAYIKAIEIDSKNARTWTNLGLLFYYHNDFELANEAFYRAQSADPDYTLAWFGQALIAIVDGHTSGATSILEHAVGLANTMPEVDFQYASSIFARTKKSGKNRASSSTTDALLPVYFVLDRYVKSRPNDPTALHLYALVCESIGQLEIGVDLITRAIALLEASYEQTEDTEVERQFTIAHLNIGRLKLSLDDYEGALESLETTLGLLSEEEDETTMLLRAQAQFGSGIAHFRMGNLETAVEFFEKAVGSATNNEFVQGEITVMLAQTLWAIGTSESRDQAKTRLLECIALDPENLTAINTLAAMGILTDDESLIDAALSEILALPIDRKLELDPQCNVDHLLIQHYLGQDDADKALRVAQSAVYADPGRLETRNQMATLLFQMQQHRSIVSVLSGPSTEYSLENESTLKLRAIAEALSTDNKANHTRAVHLAQKNIMIRPSNADNWRILAIVGTSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPM8</accession>
    <name>A0ABQ8VPM8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_790526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1279" evidence="2">
        <location>
            <begin position="76"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="24150" checksum="E8E182A5B4110550" modified="2025-10-08" version="1">MLSRFFLRIPIRLVPRVTAPLLPVTRFRQPVSTLTHTPRSNSRLFSNFPARLNSSSPGRDSSPPLQSSQENATFSQRLKHLIKSYGWYALGVYFVIGAVDFAVAFAAINLIGAEQVSRIAVSVKESVASVIHSKPPEPGKADLDPINGGMPSGNEGLYAMLVLAYTIHKTLFLPVRVGFTAAFTPQLVNWLRSRGWAGGAGTRRAAEEMKEKFRNARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQW7</accession>
    <name>A0ABQ8VQW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_817625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="932" mass="102890" checksum="F29154DFB5D8317D" modified="2025-10-08" version="1">MSNQMSPLSSSGNSQTPYPAASAPAPLSLTSQHLISSLPTSSQASNIDAQPLSGLNPGDNRTSSEILPLPPPAPCRPYASMQLSNVTDGYGRIAGSQGHPRVTTAPGFSGLTTIQRTNNMRLEHANQSLPQGSRKGKRRGKAVRPPGLSRRDQGPSIEDCISIATGGVEVVSIDVLVYLPMPPMSDINFYRLPRQSIFYEINKDAYHMVLEALGLFHQYPNLPTSTTVFDLLSDITTKLRQRYDLPSVSSSLPLAPQELLPLHLMGFSNHGRANGSFNTAKLRTMPYETTTTIRHLLNGNGVYVVPKLVITKNNHFQLHTIIRNYPLEANISLAQVYLGSDNTVRPHRCLSKRVYNMFRNDCDAKLDTHALEAGAMEESCEEDNDDSDEEDAAVVAQSLMRPASEELDDHLLHSPLIGPNALPREPSSPPPAPIQNSSITDQLLPKKLWAERWIQPPPLGFIPIFFDDERVHAIFKTVSEIQREGIVSPGFQVKGTNEQELAAELIVLMRTSIQSGDWTRILSPDRHFMRVDDQDNYVSSGPGLEQSTMTEVFHQFFEEREDEFCTTLYEDYTTLQCMDLQILPSKHEELVLFGAVTALALVYGHYPGHLNPLLLIYLLNNCDLSCLHRDLVSSYLPSVSEMLDRWLNLGPTDSIGEFASHFASYHNIQVGVLNGRSEAGHQKLASEMLHNVVIGPVGVENAYFAAFIKGFLLPGATGFNLADIVRSFFGGPEEFVRTAEASTIRDFKSLDIRIVCSLGNQSLDELAEALSVAGAHFAGKTFEDIIKDFLISIGAPCPQLLAVTKDRFSPEVKASLSGLQSPTFRMRLMCWAVTGAPRVLRDGEPMQIILVDDNDTSYLPHGLSDSLRAAYLQSGSCSFRTCSRSMRIPASYLIQLLKDTYNPDAEIKNAQVAIHHWLLIQMLDSAGTYNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR44</accession>
    <name>A0ABQ8VR44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_935002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033770">
        <property type="entry name" value="RRP44_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17215">
        <property type="entry name" value="Rrp44_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="1">
        <location>
            <begin position="326"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="755" mass="84423" checksum="A931C56A28843ADA" modified="2025-10-08" version="1">MCTKAGGKEVAVTETEVLFPNGHHILPDTNVILAQIDLIEHRSLPLYNRLKALTKSEDKHIWVFYNEYRSETAIVHIRTAAAWYNTLRGQKQTPHPTVVLITEDAANRQKAKQSWIVSVSVHRYVETMKDANVLFDLFSGERSHNIESTKAAAGRQALYPDITGELHEGHLNANQYNYLEGSIPVAAFDEPMLAPADEVVYQEAPSERQPTGRIVGIIKRNWRAYVCHIDSTSLTSTLITSFSIQTVSATLVSRLFSRIRLRTLTIDTWEPTSRYPEGHFVRALGQFEVVCGPFGKAILDCLPPEREEWIVPPKGEFDLQNIWRDRDDSRGVVVCSIDPPGCQDIDDALPAKLLRNANIEAGVRHPQDIADVSHFVVADNTMDSEAAARYLVDNGIDMLPSLLGTNLSFSSIWELTADAEIVRVRFTKSVTKSKAAFTKITRTLSDSAESSDPIDVEQKELREINSLVEEFMLLANIRVARTIEESFSQTVILRRHLPPPQTNFEKLQDILRKTNGISLDVSSSGAPAVSLNERVGAREAVFDTFVRIMVTRCMLSAGYFSTGRVPKDTFGHYGFASEIYTQFTSPIRRYGDVLLQRQLSGAIGFTPVHVTLRSKSHVERVLHVVNRQHRMTQIASRGGVEFYVGLALKVKGEQPSAGGEPDIREDAYVIRTFRNGVGVFVSNVCTLGIEGIVTFRRDTQFDAENYMITVPGAKAEVNISVFDKVVVRIEVEKNKNTQRSKVKMTLVEPVDCSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRJ8</accession>
    <name>A0ABQ8VRJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-rRNA-processing protein IPI3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_758766</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the WD repeat IPI3/WDR18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045227">
        <property type="entry name" value="WDR18/Ipi3/RID3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763">
        <property type="entry name" value="WD-REPEAT PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2 4 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="482"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="513" mass="56212" checksum="B755069CEFE6A138" modified="2025-10-08" version="1">MHLHEIIFCATASPSTTSGSGTVTLHDINTGASIASFKQTNAAPHCTTFLNSGNAQGGFFFAAQPDKLLLHAYNFQKDQISLKIVVPEKLTCVALDTSGDFFAGGTAQGRIYLWEVSSGILFNSWDAHYRQINVLRFTPDGAALLSGSDDSGISVWSMHSLLDEESQNTLSLPYFTLTDHTLPVTDILCGLGTFPECRVLTSSVDHSVKLWDLATRSLLTTFMFPQAITCLAWEPTERLFFAASSSPEGSIYQINLFRQLEDKTKGPIAEAIGGGGLNDIIRVTDESAGSQKKRLINVGQPITCMSLSLTSNLLVGTSSGLIHIYDTPTHQLLRTISTHKGLSISYLAPLLKPIDLTGHVSFNFNSSVTTIDTIPVKPIMPFQRMRDAKAREIHEVSMMLPTHENDYEDESTFYSQEALLRDHAYFTTPSNSGTRLGDTAVLQSRVTELESEVALLRGQLGQAKGVNDLMWETVVHKVIHGQVKGANNANGESTEDERRRKRGRTDSDLEVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRT4</accession>
    <name>A0ABQ8VRT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_815975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.270.20">
        <property type="entry name" value="Cytolysin/lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015926">
        <property type="entry name" value="Cytolysin/lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009960">
        <property type="entry name" value="Fruit_body_lectin_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07367">
        <property type="entry name" value="FB_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63724">
        <property type="entry name" value="Cytolysin/lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="76"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="477" mass="53627" checksum="36AB8C5F54610FD1" modified="2025-10-08" version="1">MSSRWGLGLREYPIIVAAATTSLGILLGLVIGRTVGMNSNSRSQFPVPDKILQIQPSDLLEIVEKEKRPHEPVVDIIAVHGLGSTYPSSWTEKESGVNFLKVFLPDDFPQARVLAFVYPSQPFSDPVHVDLKELGIRLLRALVDDRQGSSIKQKRPIIFIGHSFGGLVIKQALVQAGSYNSGVQGMQNDIIEATRGIIFLGTPHFGSRYATLGLIRAWVSHIVGGAHTTLLYTLLEQSLELRRLNENFLAFPAIHKIRDNIVCFFELKGEVGVFGRVVDEEYACIDSFQRISCNSTHKGLNKFSERNGEYRDIYRSIQRAYTSIVARSKLDNYAKSEYAFFCKITGDGFLVFDHDEACVRQTDTEWIIYQRGSGHSCTLLFQYEKTQTKIAVTMGVHNYAPWVFVSTDVETETAVQITASFYDDKGKRPYTHNHWNQVRTSLGKVPFSNVSATANITDMEDMEKRYQATIELSGFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS17</accession>
    <name>A0ABQ8VS17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_820526</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF874">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="5">
        <location>
            <begin position="218"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="355" mass="40060" checksum="9564E0DFDBCB3E9F" modified="2025-10-08" version="1">MSTLSTLPIVDLDIFLADPLSPAAVAETKKTAYALVTYGALVIKDRRINEEDNEKFLNLLENYFAQSEEIIKKDVRKEWAYQVGVTPELTLKPKCVFEESCMDIIEKLDPNERPLDVSGRPSDPKTRFFWKMSTPPPYETEFPLSSIPNIIPDAFADVWQTTLENWGNTLKTAVENVAELAALGFGLPRSVFTDAAKYGPHLLGPTSSNLAKYGKENTILAGFHSDLNCLTIHGRARYPGLHIWARNTGKRMSVKIPPGKFMLVQAGKQFEYLTGGYVRAGYHEVVVNDQTIETINRRKVDYPDRPLIRISSTFFWHLSSDFTLEPIHELAIRVPEDEEGKTQYPPIKVGAQVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS23</accession>
    <name>A0ABQ8VS23_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_87603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46211:SF14">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46211">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045120874" evidence="1">
        <location>
            <begin position="18"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="32"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="41467" checksum="33C72C837AB60D71" modified="2025-10-08" version="1">MVSGFLLSVLVLPVVLGTPGQYPLQRVPSKYFDVQAHRGGRGNTVESILPAFAWALIDGATTLELDNAITEDGEVVVWHDENIVATKCQDTGPAFANDTQFPYVGKYIANLTLAQLQTLDCGSKRQIDFPLQSTYPGVRISTLKELFSFAECADPDFRILWNIESKVNAEHTNQTRSPEDFVTRQHHIFINSPYRHSITYQSFDWRTLVVMKALDRSIPTSALVDLETAVMPDNETSPWLAGLRLDAFPGDMSAQIASAAHAINADILSPADVASVVVDPTLPEYVPFTTRSMVDYAHHLGMLVKPWTVNRMSIVEHLLDWNVDGIITDYPNMVRRLVQQRSRPVAPKYPKKRVLECLNRHLQKATSPSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS33</accession>
    <name>A0ABQ8VS33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_894599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="15245" checksum="C7CF553A0203E65A" modified="2025-10-08" version="1">MQFKYLTLTSAIVTAISLVNSVNAVAVWLELTVTKDKILEWISTTEANLTFIGEPITKRNTENTMVVYCSVRTQDVCGGACTVYNGGATCLNAPNTNCLSATNNVGFCDRGGCGGSCNQLSTCGVRLDDGFCYTPGTSSINVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS58</accession>
    <name>A0ABQ8VS58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_817728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="75" mass="8516" checksum="18DAB10BBFE1706C" modified="2025-10-08" version="1">MMKEKALRNSTPVSHRIVCSVLFSVSFFLSLPQGLVSKAQLPRVQLYFLGVSVDYVFFLAILYIAFNSIIIILDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSA4</accession>
    <name>A0ABQ8VSA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_754873</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="76"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="41386" checksum="CB03D27CB13DFC1C" modified="2025-10-08" version="1">MSATTVQTRTEPATATLKLHSSAEGKEETEYRYSHLLPFFSQDHYPPLTPFEHIDPGHRALNHSNPRSFLDSATQITELTPNLGTEVFGVDLRALDSDGRDQLALEVARRGLLVFRDQQEFIDAGPDFYREWGSHFGRLHIHPTSGHPQNYPEIHLVYKDANSSFNFEIDDSITSTVWHSDVSYELQPPGLTTFFLLSQPSTGGDTLFTSQVSTLKKLSPQFVAFLKTLKAVHSGVEQANFSRSGKRGGIVRREPVENVHPLIRKHPVTGEEALYVNRQFTRRILGLKREESETLLKFLYDHIDKGGDVQARVHWTPNTVVLWDNRVTAHSAIVDYGDSKQRRHGARITPQAERPVPALEDLDLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSM0</accession>
    <name>A0ABQ8VSM0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycopeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_815435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046143199" description="Glycopeptide" evidence="1">
        <location>
            <begin position="22"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="14352" checksum="046D5171C8C37F35" modified="2025-10-08" version="1" fragment="single">MLRLLLNIAASSAILAAGVKAENHTVKFLNDCGIGMPLLKQNGITLSTGASYTINGPFSAIAYLDTGCTVVETTLANSGSSTTFNLSSYSIPTGFAYFNGCDGEGWDCTIPGCPGDTGIISPFPIVCLAANVDLIITFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT94</accession>
    <name>A0ABQ8VT94_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Phosphoacetylglucosamine mutase</fullName>
            <shortName evidence="11">PAGM</shortName>
            <ecNumber evidence="4 11">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_893473</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="4 11"/>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016408">
        <property type="entry name" value="PAGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="61"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="114"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="15">
        <location>
            <begin position="207"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="14">
        <location>
            <begin position="306"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="12">
        <location>
            <begin position="492"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4499596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="59502" checksum="B277803ED0619555" modified="2025-10-08" version="1">MASSLPTKLIQSLSDLHPKPSHIHFQYGTAGFRTLGSTLDSVLFRVGIIAALRSKKLDGRTIGVMVTASHNPEPDNGVKLVDPRGEMLEAAWEGHATTISNASTSSDLIEALESLVQTAKIDLSKPANVVYARDTRPSGPGLVSALEDGFKAMSATSRNAGVATTPILHYLVKCINTKGTKYSYGDDSEEGYYRKLSTSYKKLVAGKAVQPPLIVDCANGVGALAAEQLNEYLGDALQLVLENTSITTPGALNNACGADYVKVSQKLPPSLSSVLKPGQRACSLDGDADRLIYYYLDDRGVFHMLDGDKIAALVAAFIVELVKVAGLEDQIKVGVVQTAYANGASTRYLQERLPVKCVPTGVKHLHHAAERYNVGVYFEANGHGTVLFSQPTLDKLTEYQPSTPAQSRAVEHLVSLTELINQTVGDALSDMLLVEVVLAHKSYSGEEWNSLYVDLPNRLAKVSVPNRNAFRTEDAERRLVSPPGLQTKIDELINRYQGGRSFVRPSGTEDVVRVYAEAALRTQADELAMRVAGLVYDEAGGEAASRPKEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTH1</accession>
    <name>A0ABQ8VTH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_32397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047209466" evidence="1">
        <location>
            <begin position="22"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18129" checksum="477605179B663B73" modified="2025-10-08" version="1">MRLAAAYLVTLGIGLLSAVCAIPLSTSNPVQSGPEARSLQLRQPIDRKSSPIRARFIPALVKSEGSHQPVDNSFAQELVRHFLNQEHYDLEPHDISWENTYEHDDAGLGTISFFLMDDFDSAKCYKSCIGSLKIPAIIPAPFIHGVLAENSHDWAKLNAELFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTQ0</accession>
    <name>A0ABQ8VTQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_813414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24502" checksum="98E1D5E5138CEBD8" modified="2025-10-08" version="1">MNSKQNIYVHQLKHPTESQLNAIVDICVKAYSGDIAAKIFTGGDASLDEPMWRAMICAGFYSGAVYVSSDSSVLDPIMSIGVWFGPGNVLYATEEQRALGFTKFFCQIAPEYQQWMMDDFGPKTRQFKRRVLGPTTERDSWYCNIMATHPVYQHQGLGSAIIKAVCARAAVENVPLCLGTQSDSNAAFYCGLGLREVGRMDELTPWGLFTGNMFILNSPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUB4</accession>
    <name>A0ABQ8VUB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_934673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046538366" evidence="2">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="217" mass="23991" checksum="AA456B2C0705D7BD" modified="2025-10-08" version="1">MTRLISAFLPLSTLLGVTAAPGAIRTDRQTKRLSPIYPPTPPKTPPVEATEPLDIILAGVRKLDPKSRQKFVDPKLEHLLQADAKQIPILYIGGRGYHSTLSSGKWTTQHLPGNPSDGILLGTVTLPEKSKTMLFKLLDTVQLPEKTSLLLIDHLLARVKSFPSSKAAELDLTIQGLWLPYMQVMLHQGANGAGGIITKQEEAQYQKVWEEDRFKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUF8</accession>
    <name>A0ABQ8VUF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="5">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF35</name>
        <name evidence="9" type="ORF">C8R41DRAFT_863648</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="204"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="31138" checksum="B2F42BAEE1753F6C" modified="2025-10-08" version="1">MSIPKTSWADDVDELVSGQQEDDNIRTVIEYSVNEQGKKVKITRKIKRTLQKSVVEHQVAERQKWEKFGAERGNARGPDRATTTVGENVYLTLSAGNKLLQSAESEQQEEKKPVKSTTGGKVVCRLCKGDHFTAKCPYRDTLGGLENAGDTGAGPDDDTVPPPDAASGAGPTGSKYIPPSLRAGARGTGETMRGPGGGNRDDLPTLRVTNISEDTQENDLRDLFGHFGRVARVYVGRDRDTGAGKGFAFVSFEDRAVAQKAMEKVNGKGYDNLILSVQWSQPRADPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUG1</accession>
    <name>A0ABQ8VUG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_812910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018564">
        <property type="entry name" value="Repl_chkpnt_MRC1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09444">
        <property type="entry name" value="MRC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication checkpoint mediator MRC1" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="841"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="950"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1322" mass="146583" checksum="DBFC9601A657670E" modified="2025-10-08" version="1">MPASPPDIPKRPARTYGRPKPATEVSTSKPSPNIYNSIASDDSLLNMGSDTPGEAPPTSEPSNSPLVEAENDGRNRVDGGNKDASSGYPWKWKVDLKHIDESEDEGGGSLQKTESSGDKWSKPTDPEPLFSGQRDGHILHTLASPSHETELVLSQDAFPDSPSKLAPSSFGHSHQTSASPTPSPTFLRPRVSKHIKCVESDGEVERETDRSSYSSSPVKHPINTPQTRSSTTPPTSDAEHEMPSRKAKTHSKGKSVAIMNPLVLQPAVDVDVRKAKGKRSQSNKVKAPTKKERRDTVIERQRMNAEKPVSIPRVQRSSKLTFNNLLNEIAGNTPAPLKGEDSMDPISEFSEYSSPTSNRTAVVPADTKLTEAETPRASMPELPGGADSDEEQLPDIDQLLKSLQEKKLLALQQQGQLRSGALASDDDDDLEIVNVPSTSMQVAMQKEADARKSGRPGITASTRILQKHAGISSSRRTGEVGSASQARNSRELNEVLLKRVNAENTRRTQQKTEEWISRGGKPLGPAIQASERHGLDWYAQKALEDLKETNAENGNHHQGGTDDQEDEEWTSLRGSASPALVEQDHGYEDNEGDDEEGFEDDQDITMVNEDTQDEDIPTQVTTQVDLPHRRAVRPIVNSDTEDEDNNENLYAQHRSLGKVLVQDSMILDQDSDKVYPLPQFAHRQSDSSYDGGATEDECDKENNDRLMYDRSEDKENTSVIRHELLNHGPSPGRQTSVHDLEEGLSTLDGYATDEDKENPRSPLKTLSVSEIEPFTPTAVSFVRRLERATSTASIADKAPEPLLPAQVSREFQMSGFSQFPDDGEGFRPKKLEAGFSGFFESDSQIPSSSSRPPVGSLNEPGQSNNFFDKLRRSSPLVLTQEVGLRPALEVDESLKRQADEVFEREQELIIETVNASTSKKPELYINDQGFLTQTRPDGNAEVYRPPPTPSQFFSQSGQFATQAISSQGLTRRPFRELSTSEAESTEDTPVRTNRLHRLKKRDESGSSSSAPLSNILGERSISPLLPSPRPRRHRPVESRIQKIGRRLAKSEFIEGEAQESDEDEMFGFRKVEEDEEDGEHLDRNLETLVDDKELDQTQIAKDKVMEKFQEQRQADDAHVEDVAHKLAQGHFRNGKRSRGQASIDNSDDDDEEDETGRRVRWKMKKEPELRGDIKSLAGQDATRAFAEQYQVAINSDGDPELAFLQGDDANDIIMTGPNYGKDDDNDANEDDEDDENTVNTSDIMRQLREAAKHGKDDCPAIDPNDLSFVDADNDDEDEDLPRVRHVTNANPHTRGTRKGAVGTLVFDPTEVCCRMRSFLNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUJ1</accession>
    <name>A0ABQ8VUJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_814728</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="43"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="42266" checksum="8855E7170777283D" modified="2025-10-08" version="1">MSESPQLGPLLEPLTASAHAIYPESTAESISFTPGHSDSALPPTPFLVLCLENYHSDDPIYLSFRKDELLLVLDWDSRPGWWQAQRTQPSESTDESKTDLDIAIGWIPQAYVQPLPVENYGFEQLKTEMNFALEPGTPDPQAIPVVDYLDDEWTYSEIPPGSSSKLNTSDKLKPEPTSSWHRRVRFIDDLETEFNAIKLGTSSVPVPFDALKTQFTEGGDIQLRIWIARAEANSLRRRLALPYHPNENSPGSETGGPSPALFNGSEQFSINGGAFNAVGGDIHETKNSGNTSFFNCIFNSNPKKQSSSPTTSPEDSKSQEKKRKRRWSITKFTHIFHHVYHHYLQPTVIYYPMSWMMYYVPWYVPWCQKCAVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVC9</accession>
    <name>A0ABQ8VVC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucose receptor Git3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_863290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="54475" checksum="8860E058F1D2A44C" modified="2025-10-08" version="1">MSNTTSIKLPNGEWLLTRVAYTAKEHSGVTFLLVVSALSLVAVIGLLSVISLSAFNTRSYKNDEHLFVRTHVAAYFISLLCCDLIQAIGSLYNSRWVNSGAVLLDKYCTAQGVFKQIADVGTALWTIIIAVHTFYLLVLERKPNQFTLFATLIAGWSGIFAIVISGPAVLDTVDRGPFCELLDKFSDLNCRTNIPRVGISGYWCWISDGYEVPRITLDYLIVSLNGAGPSRMLNVRYKMFVAAFSCFVLHGLIHLRLRGNMSMKGWRMTFYRQPQERPTGRNFDDKGMSIARQMLLFPIAYCIIILPIAVSRFAAWNGHIVSFEETVFCETVFLLSGCVNVTLFCTCRQILPPKSLVLLKRSISKPKPIQRAAATSVAVSPESDPYYAASITTTVVGYGFDKGHDADIEKGSLSDISAPMGEGSSRVSDPYEQTVAPLQIRKSVRHPRPPSVIIPNRELDDVYNMYSGGQPDAYTGDFNDVNLGSGHHPSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVL7</accession>
    <name>A0ABQ8VVL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ER lumen protein-retaining receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_893082</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00952">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10 11 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="24826" checksum="E947AF7D41629055" modified="2025-10-08" version="1">MNLFRLLGDLSHLASILILVHKIRTSRSCRGISFKTQALYVAVFVARYLDLFFRFISLYNTVMKVFFIGSSCYILYLMKFRYRPTNDPSIDTFRLEYLIGPCVILSLIFNYQFWFTEILWSFSIFLESVAILPQLFMLQRTGEAETITTHYLAALGIYRALYIPNWIYRYFSEGVVDPIAITAGIVQTGLYIDFFYIYFTKVLQGQKFELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW80</accession>
    <name>A0ABQ8VW80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_479776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="84"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="313" mass="35183" checksum="47CAF8C40E694BBA" modified="2025-10-08" version="1">MNPCIIMFISLSVEVIVGLEISAKSCFLMSMGLLGLILRILGLFSNYPRRLLLPYLLRHSLKLPGGPVLLLPDGTVVKVGNPVFLQLEAEATKYARDHTQLPIPRVYDFFTSSDGHKGYLVMQHMPGDMLQRKWRFLSSEQRNSIMAQVRNMIEELRAIPQPEPQGWIGSSSRGAFRDFHIRSNETYGPFPSEAAFNTFRMGCFAKFSYSEEPTTKARLARIGREMPVASDIVFTHGDITRRNLLVEVDDNAKVVGIIDWEQAGWRPAYWEKVKIHFGGGTGSGWFAGGEFEGYEDDIGREVELHLIHGGGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWE5</accession>
    <name>A0ABQ8VWE5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="14">ATP-PFK</shortName>
            <shortName evidence="14">Phosphofructokinase</shortName>
            <ecNumber evidence="14">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_750780</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14 15">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="14">Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="14"/>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03184">
        <property type="entry name" value="Phosphofructokinase_I_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009161">
        <property type="entry name" value="6-Pfructokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02478">
        <property type="entry name" value="6PF1K_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000533">
        <property type="entry name" value="ATP_PFK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="122"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="462"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal catalytic PFK domain 1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal regulatory PFK domain 2" evidence="14">
        <location>
            <begin position="462"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="176"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="357"/>
            <end position="360"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="531"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="588"/>
            <end position="592"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="626"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="633"/>
            <end position="635"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="719"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="800"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4500683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="835" mass="91335" checksum="149DEE1171698D4C" modified="2025-10-08" version="1">MKIAILTSGGDSAGMNAVVRAVVKVGILKQVYNLTSYLLLLTNFSRGCETWVVREGYEGLVRGNTEALSEQSLDEEPVDLPDNTSPDGTSFNLIHNLRFGDGDLLKDGTGDHPGTRSLKGRYIVRVGFDDVRAWFAEGGTLIGTARSKTFRTPEGRLQAAYNMIKEGLDALVVCGGDGSLTGADVFRAEWPKLVEALQSEGRITAEKAKLHAHLRIVGLVGSIDNDMSMTDLTIGAPTALHRICEAIDNINSTATSHSRAFVLEVMGRHCGWLALLAGVSGGADFIFIPERPPTSESWEDEICECIHRHREVGKRKTIVIVAEGATDRDLNPIKADHVKDVLTERLGLDTRVTTLGHTQRGGRPCAYDRVLPTLQGMEAVETLLEATPTSPSYMIGIQENKITRVPLMEAVAMTRAVSAAIEAKDFEKAMSYRDPEFKESFEGFLKISTLDQEKVPETQRMRVALMHMGAPAGGMNAATRAAVRYCIRHGHTPIAVHNGFRGLLDDEVHGLSWLGVDSWTARGGSELGTNRTLPSVDLGAVAAKFQEHQFHALLMIGGFETFNSLLIMEEGRRHYPAFHIPMVHLPATISNNVPMTEWSLGSDTSLNALVDACDAIKQSASASRNRVFVVETQGGKCGYLATVGALATGASLVYTPEQGMDLDTLRRDVRFLKTRYKLDAKGRSEGRLVIKNEVASQVYTTDVMQKMLKEEGGTLFDARSASLGHTLQGGVPSPMDRARAVRLSLKCMAFLEREHVKLLQQPVKARHATPDSAAIITIQSSSLKWVPVQEMVAHADMQNRRGKNPWWANIKELAELLAGRPQLIGIHSKDLAQYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX35</accession>
    <name>A0ABQ8VX35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_913955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="351" mass="40575" checksum="459E1973E9BD702A" modified="2025-10-08" version="1">MENNITSDSSESEHSSAQRSESEYSSEEEDDSEIEKVSDSNFYSENHSDEDQSKSKDHSDNESGSDDQYENSEPDDSSDSDHPQNTYQHHSQRRRLSENKRIEYLATGRCFRCGGYGHISRYCPNGYITEASWKNRTADIELGMMSFALNEPVSPFENDNRKTVQEAGKHSRSMGKKDFVFNGHREERKEGGRMDMALTSRKRHMKKRKPTPGIDFALEDLPERHQHIIDSNLLPTKNGGYEHLTSLKRVRNNKILIKPYDGYTHFVTVSDVRTCLDFDRILRKRSFKLRTADIPAIYPLFAERVNSDPVIRPYQLATFDVDTGIVYTQAPPVDRRLFDPFTREDDLRINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX76</accession>
    <name>A0ABQ8VX76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_900590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="410" mass="45403" checksum="B93D526346FB23CD" modified="2025-10-08" version="1">MPRNLVAVDLTSTKHDEFRKPPVTPIFQISMQKQLRRNLVYIEDAKNIVDEKAARGSLKPQEQIYLDHLYNTSLSGNQSLLSAAGSKEKMRDNLNLKKRAKVSQATEDAGIFGQAVWTTSERIRQEEEAIRRGAFMRREFSESTVSRNDHGQQWHQNMPNPAITDVRHSFGSYISPGPQRRLFVANPNSRNTSTAGSLLGSRLDCNLSPSSTGPSTGAICCHCANPNSRNTSTEASLPDVRHSSGLYIPPGPQEIPYVMSSSYRNISTEGIPPSSRMGSDLSLSQQTAMTGSFGSGYYPRSGSVNTASLEDDGTHFSMGSRVSGSSEMYQLDPSTGYYSGEPGSSRYPAMYNSGQEYYRNQTQMTGMECIITDQKILDAIMYNMMMLTSLVVTGVCILKQGLRDTEQYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXC9</accession>
    <name>A0ABQ8VXC9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_812473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="4">
        <location>
            <begin position="83"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="225" mass="25584" checksum="0043E6CBBF2A23AE" modified="2025-10-08" version="1">MAKANIPLPKPKQTREDNDHQDVSVSVENASEHTGFVQALRLILYLIIFIALAGKFLTGSYVWEYEGKWIRLRTYFPPPQRLFTERELAKYDGMDPDKPVYLGIDGDVYDVTKGKAYQPGGPYHVLTGVDAARAFGTGCFKTHRTHDLRALSDAEIKGIRHWKKFYENHPNYFKVGTVLHPPIDPSSPIIEGCDTKNKNKSGAKKDTAERRALVQERDPNIHQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXR8</accession>
    <name>A0ABQ8VXR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_915510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF44">
        <property type="entry name" value="PHOSPHATASE C1620.13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="188" mass="21544" checksum="2BEB4FD650B55057" modified="2025-10-08" version="1">MSVKRFHALRHGQAIHNVQRGWPERDPPLTEQGLAEASGVPLTFIPDLIICSPMTRTIQTLYAILSKLKDHPTHSSSIGNEPDIRVEIWPELRETHDHATCNLGRSRVELEAAYPSLDFSRCHEEWDYPGHTDERAFQRAEALLQELKGRPESNVLLISHRGILRYIFGGEIFRNCGRKHFRASRLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY18</accession>
    <name>A0ABQ8VY18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fragmin60</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_749749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11290">
        <property type="entry name" value="gelsolin_S1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF130">
        <property type="entry name" value="SEVERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00597">
        <property type="entry name" value="GELSOLIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gelsolin-like" evidence="1">
        <location>
            <begin position="65"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="1">
        <location>
            <begin position="310"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="405" mass="44967" checksum="D6CEA6B0054CF08D" modified="2025-10-08" version="1">MNEHLTKPTKYDIEDSNIALLGSDLEKRVREHGGDKETAWNEAGATTGLQIWRIEKFHVAPWSLKAEEGRFYDGDSYIVLYTYKKTPESESFSYNLHFWLGDETSQDEAGTAAYKTVELDDYLQGVPVQYREVQGYESDQFLSHFPHGFVCLKGGISTGFHHVSDMPPVDMHKLYRISITPNLHPSKSHAHLVAIREVPFSGSSLIEGDAFVLDKGTKVWQLNTKESAGKEKFRAAEFVRSLTGNRRGGCQVTVFDEGGHGTGIFLAEFGEGTIIHHDTAQSDLPDGSTPTLNLYRLSDFSGTPSFSAIEPPITLSSLSSSDAFILDNTLTKTSSAVLYVWLGAQSSLTERRLAVQYAQRYLHDKIGVNATTTTKSRNVVAIPIVKMQEGHESEAFLALLRGEDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYE8</accession>
    <name>A0ABQ8VYE8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_807838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11238" checksum="0C5DD910B147F527" modified="2025-10-08" version="1">MYHSKLIAMFCQSVNVCVARNVIPLENIVGQRWMNKSNNNPTGIGCTYKMSRLSAKYAVMYLVVSCHSALLSRLFLLAYNCFGHSLPIVRNVMYCWPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYQ3</accession>
    <name>A0ABQ8VYQ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_804938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="272" mass="31303" checksum="CA9ABD1EB8DFE60E" modified="2025-10-08" version="1">MDFSPVGNSYADVIQRIRKFRAFDEPEKKHIFQSFTEFCAPYKPPVTLGKPGDVFLNRKTYKLYMREDSQWTQWLSTSDSSRLKYPELQNRFLWIVPNSGQRMVDFVPSSILKRFKILDATELLKSIVSLQQKQDQTRKRKSESSLNTKKGKKGRLSNIEPPVGWSGIDDLPTQLLTSVSAPVPRSNLMSSLSSTAPLQTPGSSSSRVSLHNSVSMSPQIQRDKKLLERNKLLERENQELKMSLRISKELEKDSHMVRRLHHIASEVLMSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYZ2</accession>
    <name>A0ABQ8VYZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="131"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="34100" checksum="FCDE75A0EA35DC24" modified="2025-10-08" version="1">MQSKPRSRSAPPFSTHDFGIGWELREDGYELEDLHMDPHDLAEFSSVEIFRDLHPRAMYWVDEDKVLKLFSYLIDVSVIVANMDLARTRLPVPRVLRYGRSGNCSYILMERIPHSTLAIEMDQLGMNFMPWQLTQTMDHIVRELADLGLTHNDLVPRNVLVDKNGMISSIIDWDPCTPHHRGGEYARKIRNFDLHWRYGEKEWYHIFLRYSFDRTGEEISIGCSKRHPKLYLQWPLVKSKASQLIHPPITDCRYQSFSRQNIRPITVEPMINAFESVHIRGSASPNLTHDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ18</accession>
    <name>A0ABQ8VZ18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_912901</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06593">
        <property type="entry name" value="GH31_xylosidase_YicI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007940">
        <property type="entry name" value="PRK10658.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF4">
        <property type="entry name" value="MYOGENESIS-REGULATING GLYCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117125">
        <property type="entry name" value="Putative glucosidase YicI, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="6">
        <location>
            <begin position="55"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="5">
        <location>
            <begin position="288"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="7">
        <location>
            <begin position="553"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="729" mass="81409" checksum="A0BAF125F695ACBE" modified="2025-10-08" version="1">MKFIDGFWLLKNGVKPYYALQVVKVDQQTDGYELQVSTKPIRHRGDTLGGPVLTIKVHSPTEGVVGVKIDHFNHSEPTVNIPLFPNAKPIPNVNLSKAGSDYTLSTAGLNAVITENPYTITFKSPKQILTSAGPKHQGVFDVPSQWTLSSASNSSCLATDIGSNPNPEPLPPIIRYINSELNLSPGELIYGFGEQFGSFVKNGQTVKIWNQDGGTSSDQAYKCVPFYLTNRNYGVFINHPGEVEVEVGSEKVSRVGVSVAGSSLEYFIIYGETPLQILERYTRMTGRPPVLPSWTFGLWLSTSFLTSYSSETVSGFLQGMQDRDVPVRVFHLDCFWMKQYEWCSFTFDPDNFPDPKGYLSEIKRKFGVKICVWINPYISQLSPIFKEGITGGYFIQRTDGTPWQWDLWQPGLAIVDFTNPKACEWYLAKLNALIDIGVDCFKTDFAERIPHASVKYFDGSDPMRMHNMYSIIYNELVFNLLRDRLGEGEAVLFARASFAGGQRFPVHWGGDCESTWEAMAEAMRGCLSLTLSGFAFASHDIGGFEAIQSTETGHPMQRAMFLEFPEDRNTHYLDRQFMMGPSLLVAPVFVPQEEETEYYIPAGRWTNFWDHSRTVVGPIWIKERVALDEIPVWVRPGTLLLRGPPNTGRPDYDYGKDLRVELFDVAEGETLAKVPGGVVIRADRQNGKIKVTIIEGKASINSIFSVGAGGKERVVKVDSGATEIVCELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZB3</accession>
    <name>A0ABQ8VZB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_9119</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DH" evidence="10">
        <location>
            <begin position="166"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="11">
        <location>
            <begin position="895"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="617"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="832"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="968"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1074"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1261"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1323"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="643"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="843"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="866"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="968"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="990"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1261"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1274"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1373" mass="153202" checksum="538D53ACB9D39C4E" modified="2025-10-08" version="1">MTHNLNSIVAFPSSNHQDRTSVYSVQSSISTNSNDSLPQPPTLPYLPFRRISLPSLPPSQSIQHSPLRRQTTQPLQPQRSSIASFDSFPAIEERERRESNSTARNHLVPKSRKSTGFSNSNVTPRKGQRKTAVSMQTDLRPPSISPMRRKSRGLSVLPLDDPLLVKRRKVMIEFYETEKAYVEGLDLIYEHFLLPILNSLDRPTPILERPLLTAVFSNFVDIWNLHHSFYSELTRLFYASEQKRSDLPSSSLSTTQLQEPTDDQTFSVFPSSPPPLSPVLLTHFPYLSLYTPFITAFPQILSALNTLLTPTHYYRQRAQAQTRAAARAQSSTPSSITSPSKGIELKYEKRFADFVATQEKHPRCGKLQLRDWLLTIVQRCPRYLLLLRDLLSCTPGEAPLPEEGKEGVQEKMAEDKRRWYREASKEEERERERLIQVFGLVSKITNSLNTSIWSHSQTLALLALQRSTPNLPLDEFQFISPGRTLLKRGTLLQVENPDARVRRGESKDGDMRPREREFLLFSDCLVWLANEEAEKKEKEWNFELDLGSIWSSFMGSGTSSPEKSVGVQRPRSAALVKSTPLIVEEEFDIDTIDKPDDYNSLDHKTHVIPASAIPRNLRRPPMVRTRSKSEAELPALQGKAAVPSTSHDSPPSSAQTQSALAVDKNARRITHQSKFSRTNKNPVLHIHGRGRKDSSTSPGYGGMDQDQWLYKGRIELVNLEIVVDTSFTVEDELEELGSDTLNEIKWRWEVLSPEGSFVLYAASVQERTEWTTLIRKAKSQQLVALNAQHPNSTLTSSEATQHIRRALQALPFAPNDVRMQGFKVEKRLSKCSVDSGDGASVDGIKEGIKKGKERANSSKKHRKSRSKDQKVSNPDWHKERRLKVEHWVPAIWIPDEKAEGCMRCGRIFGWRRRRHHCRLCGRCVCSSCSEKTFYITDPNINDDDAFSKSARACNACYESVFPLIDHHHDPKNKADDSTVRTRSHPPLAHSSVSGSTSSFLPPSTSTMTYVSNTDTITSLSHLPSWMTMSVPSLALSSSSDNFGVGARIKSKGKEISGPEALMAIDSKRYGYGLERRRQSDNSGKNRTSRDSGVVFDLDSSTDDIALDDVVQPMRRGSRIKLRSQSSSGSRPRSYIEVFHSAGVSDTPQPQTLMQATSPLEEMAEFDEDTIARLAYVDGEDSSVLSSSSVNSSRRHTTINLSTSSSLVSLSISPPISSGELNVNGRSPLSNASLAERREDTVRRNKRFSMPAVALQTTSVVARTQSMSPETSEMFSREKSGSDLGRDQEGKRVTGSKIGDLLPGMSGTRSKRFSLVLGGRLGHSTGIHTGGRNEHASPSSRRKGGGDGNKTQKGSDLGKGVAASRLNELLGRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZB7</accession>
    <name>A0ABQ8VZB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_201852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039931">
        <property type="entry name" value="EEIG1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456:SF1">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="2">
        <location>
            <begin position="41"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="43022" checksum="601836B9EF99A09F" modified="2025-10-08" version="1">MHTPLTPTHQNGHGHRHHSPARPNSKHSHSDPPTHGLRAQLHNLLPRHSLFHAHIHIHQISSVPLVHGEFAARWKFKNVQSQTGLLKRVKGKRRGSHKDEKGKAKEVVDEGDDSFGSGEAAADRHSSSSNSIVDDQNVNIPAVVVSGYMSPTAAHPKSPYQELLNPPRADFSRTSSALTSSSASYSHSGSSANLPQSLSITPITSNSAPPTPSIAGVESYSNTRGMTPFYKLKDHAVVWDHDLDVIIKMDIDRETSELLPNEFKLVVMQRVIPGDPDAPRNPRLGALYLDLSEYAGVGKEVTRTYLLRDTKMNATVKLTIYLEHSGGDTNYIAPLLPKAEIFNGVADLLDDDVYITRPRALDLWGPYHNQQELEMDLLGGRNPGLEPVPSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZT6</accession>
    <name>A0ABQ8VZT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="412" mass="45924" checksum="773C3C92F891E82F" modified="2025-10-08" version="1">MILDDKALLNPPPPYSYDILSHSNLSSIDRDGETASSVGDNNPYHSARKSKPMFSSLPSHLLLQIVYCTFPWKDGQFEGDVKEVLQRRTLYWLETSLRFVNRDLYIACMHILRSTYLPSYDSLIRPPYSSDPFPSSNSVPLYGTSTSLWNSPYGSSRLFPQHRELQTLDLFIAVLAQEELLYDTSSLHLSRHEAYKDIFDLRQPQSRLEDLVAKEGVKAGLVTLGDGDSIPDTPTTHQTPSEAKGKENSPYFMDTDNNSSLLALPRASTSSLSKPLKKAKSSFSLFSAFSSKGKGKGKAMIAVQRLSQPTERKVLLSPLPFRSLSISFSTRKISLMYAPSYCAGSKSSLTVTGTSSSSAYGGTTYGALGLSYNSHGRKRTIVEVQRDRDEALEVSVRRVVRGLREWMEEEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZU0</accession>
    <name>A0ABQ8VZU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_813169</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005588">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="127" mass="13972" checksum="E5AF4D06F78C440D" modified="2025-10-08" version="1">MAPKSSSSFTFTKPSSQSASSSLSALLSAYTTQTTPRLKFIDAFLVFLLSSGVLQFVYCVLVTNFPFNAFLAGFSSTVGQFVLTASLRQQVNPENKVEFKEVSHERAFADFVLGSIVLHFFVYNFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0P9</accession>
    <name>A0ABQ8W0P9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I glutamine amidotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_426945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="131"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="262" mass="28741" checksum="6FB6B65DD4B7B823" modified="2025-10-08" version="1">MSSSVESSLIVDKTYHLAVCLFPRVTTLDYQGPIELLGCFPSDLRAEPNSHLQFFKDYLPPFAIDVEYISHSEDPITPATGPNVLPTGTYEGVMKSGKQFDIIMIPGGRFPTRLGPALIRNRVCYLTGPLTNPNQVHPSLLQFLKQQAPGVKHILTICTGSWILAGAGLLNGKKATTNKLMYNVVKESTKDQNITWIPKARYVVNDDKKIWTSSGVTAGMDLAHAFLEYLAGPDTANSLGNLLEMNYKDEGDDDFAALHGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W126</accession>
    <name>A0ABQ8W126_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase 2C-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_874019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="397" mass="44715" checksum="3C10703F5A07B8A0" modified="2025-10-08" version="1">MDQQTWLKQLSIAFSQKCIKSLDVCFDNSRISQAGFQAKKPLNEDKTVFLESPLGLIIALFDGHHSDELSDYASKTLPSLLFERIQKTLIEQGCTMDEAVVTSLIQGIEEYDRWLIQDVIDEFPQKDKTDWSDSFWEDEREVFSVLGWLKEHPKFQRARYAVVGTTALIAFIDRAKENVWVASLGDSDALLGQKRDDGVNWEVSCLSDSHNGQNAKEVERVQAEHPGEPRVIQNGRVLACLTVTRALGNHQLKTPYHFAKNILRFIWPSPFPMEVLDNCVSPPYISATPVVRHHSIQPGDILVLSSDGLANELRNFDEDNKKKLIISLSLDSDVDSFSENASWSNQLGHKFILAQDGDNPAERLIKNVCFGTDLGKMAEAVNPSEEWDDISALVLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A1A1</accession>
    <name>A0A9W9A1A1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_537487</name>
        <name evidence="13" type="ORF">C8R41DRAFT_815097</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000029">
        <property type="protein sequence ID" value="KAJ4471314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A1A1"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000131">
        <property type="entry name" value="Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000236">
        <property type="entry name" value="Vacuolar protein 8, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000128">
        <property type="entry name" value="Vacuolar protein-like protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="89"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="130"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="171"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="212"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="255"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="296"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="10">
        <location>
            <begin position="337"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="528"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="575"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="578"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="595"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4471314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4499284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="615" mass="66583" checksum="451594A3D2485C0E" modified="2023-11-08" version="1">MGNITSCCDSCFGSRRSQAYEPLLLENEREAVADLLQYLENRTTTNFFSGSPLTALTTLSFSDNVDLQRSAALAFAEITEKEVRPVGRDTLDPILFLLSSHDTEVQRAASAALGNLAVNTDNKLLIVKLGGLEPLIRQMLSPNVEVQCNAVGCVTNLATHDDNKTKIAKSGALVPLTRLARSKDMRVQRNATGALLNMTHSDENRQQLVNAGAIPVLVSLLNSPDTDVQYYCTTALSNIAVDGANRKKLANTEPKLVTSLVMLMDSPSLKVQCQAALALRNLASDEKYQLEIVRADGLSSLLRLLQSAYLPLILSSAACVRNVSIHPQNESPIIESGFLQPLINLLSFKDNEEVQCHAISTLRNLAASSEKNKTAIVKAGAVVSIKELVLEVPMNVQSEMTACVAVLALSDELKGQLLEMGICEVLIPLTNSPSSEVQGNSAAALGNLSSKDGRTANDDYSAFNDVWDKPDGGMHRYLYRFLSSPDATFQHIAVWTIVQLLDSGDPQLISNIRSSTLLVPNIRNLATSQASTPSSSVGSHRSHSYDDTETNDGQGEIQLLSRRILEYVDGDLEAMAPSSLTPSHMQPGSSVASSTRDHEELRRSVREAFAPGSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AFL5</accession>
    <name>A0A9W9AFL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L6, alpha-beta domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_560197</name>
        <name evidence="6" type="ORF">C8R41DRAFT_756639</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR11655">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <begin position="12"/>
            <end position="87"/>
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    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="99"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4481661.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ4498629.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="191" mass="21265" checksum="16D5F7AD677A10CF" modified="2023-11-08" version="1">MRDVLQTEELVIPEGVTVALKARIITVTGPRGTLTKNVQHVNMDIRLVKSKDSKVTLAVWQGGRKHVACLRTIKSLISNMINGVTKGFRYKMRAVYAHFPINCIIQSDGHAVEIRNFLGEKTVRHVNMLDGVVITESKAQKDELILEGNDIDMVSQSAASIHGVCRVRNKDIRKFLDGIYVSNKGVIAEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
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        <name evidence="3" type="ORF">C8R41DRAFT_213938</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
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        <lineage>
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            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AGS3"/>
    <dbReference type="OrthoDB" id="2351920at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="190" mass="21146" checksum="085C399063FD997D" modified="2023-11-08" version="1">MTDLTYCYLHMSKHDLQVLDTLETSDYIKGELSDEELDIPQHMVPPNPDDSDNLPSHVHPSYPYGNPRSIKHPASRPRPPYDPTSRALFEDMGYDGSGVAGTLRWKDLALDQLLPVDEEKETALKAAEARKMASGTGNQNPQTQQQPAALAPGDETIDEEDDEDEDDESEDDENDDEADEDEDSEEDADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AJ61</accession>
    <name>A0A9W9AJ61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GTP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_511056</name>
        <name evidence="7" type="ORF">C8R41DRAFT_898328</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000013">
        <property type="protein sequence ID" value="KAJ4482936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AJ61"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032161">
        <property type="term" value="C:cleavage apparatus septin structure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043934">
        <property type="term" value="P:sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000260">
        <property type="entry name" value="Cell division control 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="6">
        <location>
            <begin position="28"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4466563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4482936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="313" mass="35672" checksum="DE40E6BAF4EF83E4" modified="2023-11-08" version="1">MAEEEIIANSYVGFDTITQQIEHKLLKRGFQFNVIVVGQTGLGKSTLINTIFASHLMDSKGRFAADEPVRQTTEIQTVSHVIVENGVKLRLNIVDTPGYGDQVNNEGCWDPIIKYIKDQHSAYLRKELTAQRDRYIQDTRIHCCIYFINPTGHSLRPIDVIVMKKLSEVVNVVPVIAKSDTLTVDERLAFKDKIREELVYHNIRLYPFDTDEDDEEEVSLNETIRSIIPFAIVGSENNVIINGAPVRGRKNRWGVVNVEDPGHCEFVNLRNFLTRTHLQDLIETTAQIHYEAFRSKQLLALKEGVNQRPTTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AKB5</accession>
    <name>A0A9W9AKB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_452608</name>
        <name evidence="7" type="ORF">C8R41DRAFT_893454</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000011">
        <property type="protein sequence ID" value="KAJ4484788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AKB5"/>
    <dbReference type="OrthoDB" id="10264538at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000003">
        <property type="entry name" value="60S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018256">
        <property type="entry name" value="Ribosomal_eL13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01104">
        <property type="entry name" value="RIBOSOMAL_L13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="208" mass="23823" checksum="A12AB97A26D6C201" modified="2023-11-08" version="1">MGFAHNNVLHANHFRKDWQRRVRTWFDQPGRKLRRRNARKTKAATLGVRPLTLLRPAVRGQTIRYNRKLREGRGFTLAELKDAGIGRKEARGVGIVVDHRRRNLSEEGKKLNVERLVAYKQKLIVFPRKAGKPKKGDSSTEDLSATTTRVTLPLPESFPAEAPRKITAEEREFEAYKSLRTARANARHEGARKARAAKKEEEEAAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AMU5</accession>
    <name>A0A9W9AMU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8J55DRAFT_20030</name>
        <name evidence="2" type="ORF">C8R41DRAFT_771121</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000010">
        <property type="protein sequence ID" value="KAJ4486529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AMU5"/>
    <dbReference type="OrthoDB" id="2501127at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20598" checksum="11FECEF2396F9066" modified="2023-11-08" version="1">MGKLGWIRVGLYSALLVFSFILLALSCARINYTLHIPRGDPLNGGRDFYDPVIPELIFTTLVTMSWSGLMLFVFFDDALKLRFLRLYGDELIGLAILWIFWIGGAGAASSLWGDLSFCQQFEACRILSALEAFAWLGWLILTAMIVLSIVVILRSRNIGGKGLAEPLPTRVGGDDAVGGRKTNVAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AVB2</accession>
    <name>A0A9W9AVB2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_422597</name>
        <name evidence="4" type="ORF">C8R41DRAFT_769951</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000007">
        <property type="protein sequence ID" value="KAJ4489392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AVB2"/>
    <dbReference type="OrthoDB" id="6224010at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4483988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4489392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="59" mass="6663" checksum="30A03D953769D3EB" modified="2023-11-08" version="1">MNALSRREEETLLKTVKAQALKECDPFVKDFADCMSGRLISVAWACKDKLKLVEACMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AZQ4</accession>
    <name>A0A9W9AZQ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucocorticoid receptor-like (DNA-binding domain)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_418148</name>
        <name evidence="4" type="ORF">C8R41DRAFT_775687</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000004">
        <property type="protein sequence ID" value="KAJ4492987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AZQ4"/>
    <dbReference type="OrthoDB" id="413436at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1480:FF:000001">
        <property type="entry name" value="30S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4473502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4492987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11911" checksum="132BD277737D3124" modified="2023-11-08" version="1">MGLRPNIRVLRDMKARQGVLDNEVTRRAYLFVARNQSLPPQIRHQAQLQLNTFGRYTRPTTVKNRCYESGRGRGIMSEFGLCRYQFRLKALAGLLNGVKKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW34</accession>
    <name>A0ABQ8UW34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_154394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000160">
        <property type="protein sequence ID" value="KAJ4463532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046064865" evidence="1">
        <location>
            <begin position="18"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="129" mass="13276" checksum="B4AF98A1F5FA67FF" modified="2025-10-08" version="1">MISTKSFFAAFVAFVGAQVVSGAALAPATITACSGTINPPNGCVDIPVVSDDCTDFTGGLSFLNKEISNVEVPAGFVCSFYEEFGCLGSQNAHNVVVLTGGTWNMESVPGIASTQDFNDMASSFTCSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW93</accession>
    <name>A0ABQ8UW93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WWE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000154">
        <property type="protein sequence ID" value="KAJ4463704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="24916" checksum="963973F2C85AEDF8" modified="2025-10-08" version="1" fragment="single">MTWKEYDDRWVDFDSEVKQIIYEAIGCDEAKEKPPLGYKIEGSPAKENLISLNCADDWNGLCEDVLSKQNEKKKLFKVSITASPKYMKGLKDWMDKKNKSRKGKGKTPVQRGSGKSDSGRKFHFDSSSNGSNSEDNGAEKSMMEVEKHHIDELRLEYGKCNLHKPQPCKIARGTHTILMFNMLSAWARALANKDTGITVKTPPKSESFRAFHHSIETTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW98</accession>
    <name>A0ABQ8UW98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">S-adenosyl-L-methionine dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_852998</name>
        <name evidence="6" type="ORF">C8R41DRAFT_861112</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the methyltransferase superfamily. METTL16/RlmF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000155">
        <property type="protein sequence ID" value="KAJ4463701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017182">
        <property type="entry name" value="METTL16/PsiM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037350">
        <property type="entry name" value="Mtase_ZK1128_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR037350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4463701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4469315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="53702" checksum="69AC70904A95FA14" modified="2025-10-08" version="1">MHSRNIYRNGIDFAELSAVYPPLRKYIDKASNPHKTIDFKDQDAQRCLTEALLHRDFKLKIRLPPDRLCPPVPNRLNYILWLQDITLASRYLDEPNTQSIVLGIDIGTGASAIYPLLACSLEKSWEFVVSEIDPSSFVTARQNISTNELDDRVQIIQSHAAVPILLPLHLDKERRFDFTMCNPPFYSSLQEVIQSAEAKQYGPNAVCTGAEIEMITSGGESAFVGKMVIESLDIRERCKWYTSMLGKLSSVAEVVDILKCHSIDNYIIMEFVQGQTRRWAVGWSFSDTRLPDTISRIQNPNPTISKYLPTHNTILQPVVSVSRGSLYERLSSILSSVAHIHIRSQGALSVGAPAETNGIRPGPNLGYLVSVQENTWSRSARRRKKRRVDDLESNVGPDRQNIAAASGERLASSHMACSIMVKESFKNTNFAFGAKEDQDSSLQDFIVEFTWRKGQVRELFDSFCSHVSRKVVTSTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYK9</accession>
    <name>A0ABQ8UYK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_780988</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="8">
        <location>
            <begin position="62"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4466035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="19607" checksum="10A50622D1E78E9D" modified="2025-10-08" version="1">MSSTPSKYKETSSRCPFPGEATECEAANDKSQSQSVNPPARSRSKKTFNPQLILENNGSVARDHLASERTFLAYVRTSLAIASTGVALVQLLTISVDASTNRSTTSLTTEPTSQRMQAYAKPLGSAFVIFSIVLLITGLTRYFSIQNALTLNQFPVARLVIIISSLILSALVIFTFAILVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYL7</accession>
    <name>A0ABQ8UYL7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_891120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF199">
        <property type="entry name" value="MYB-LIKE TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="58"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="58"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="109"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="114"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4465710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="410" mass="45742" checksum="0F9ABDAEE9FF79CB" modified="2025-10-08" version="1">MLYRERRSWTEEEDQLLRDAVDLEEPGSINPSKWHAIAKHVPSRTNKDCRKRWFAKMASDVVKGGWAPEEDEKLVQAIEKYGTRWSLVSAYVQTRNSDQCAKRWTDTLNPMIDRTRWSAEADALLLNAVQEHGKLWTKIVRIYFPGRTGLAAKNRYNSITRFSTRAPRRKSYKPRFESESASSSISNSPSISSMSSSSSTSDTSEPPSTPPSFELNTPLISDPNSEGLPSEFMLDSTTWSAIESASLECTSHCLPSTTFTYEDLCNAMASSSDLINDAAGLPDYSDSKSSQNPLSTLPWEDETYSHIQHTIDLCSNSAILSSSHPLDSFDTFLSYQNLDHSSTALSPLPMSSMSDTSSAITLLPADGETTNSLNNSSHVHRHEYGYATVPFWEPANSDPHSFLAQWTSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYR8</accession>
    <name>A0ABQ8UYR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_725267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039323">
        <property type="entry name" value="ANKRD_45/46/60"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677:SF4">
        <property type="entry name" value="USHER SYNDROME TYPE-1G PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="75"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="207"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="30203" checksum="447E30FED2FD0BDC" modified="2025-10-08" version="1" fragment="single">ADVNAQGGRFGNVLQAAAYQGNLDIVKFLVENKADVNAQEGRFGNALQAAAYQGNLDIVKFLVENKADVNAQGGRFGNALQTAAYQGNMDIAKLLVENKADVNAQGGQFGNAMQTAAYQGNLDIVKFLVGNKADVNAQGGQFGNALQTAVYWGYLDIAKFLSENKADVNAQGGELGNALQAAAYQGNLESVKFLVGNKADVNAQGGQFGNALQAAAYQGNLDIVKFLVENKADGNLESVKLLVENKADVNAQGGSWGNALEAAIMGGHLDIVKLFVEEKDVDINALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Q2</accession>
    <name>A0ABQ8V0Q2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="41180" checksum="ADDC7231B6B34AD7" modified="2025-10-08" version="1">MEDETTQRTGRLSHRICALKLTELANKANFWVSDSFTVVWKSPHIRSEMERKQRELTHEDRGKLFALLSVHSKATTFAAYIYEPYVHKVFSTPGSISGSPSDLPPTQPMTYRPRTCVKCGSKSSACPHTTDCVYETTTEQYSVYDDFFKGQRDYEYEKLPDWAQLDLDCYYRPVQPDNPFFDSFILRDGGSYIVAAFIQISIARGRGHTHTTISAVTIITEVRENARRRFHKPVEIIYIYVAPDVLPTAKYPLRWTVDKVYLTQPVVSDAKVNEVQRVFYLGVPLPHNATQVANARHALSVRARSQNAMIYPDVKTLHEGNRGTKEPADKVRRTTETDAPSSHTATSNAGGRVGRKVRDKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0X9</accession>
    <name>A0ABQ8V0X9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_854142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="385" mass="42868" checksum="D18D71A457306F4C" modified="2025-10-08" version="1">MHLNEGHVFEKVHPYSGHYSGSRPARPSASSAKSVSSRSSSSASVLSYAYAPTGDERYSKVLKMGSKSGSTEGYGGNAAAAANVVVQDVNNDGVSRRSQYRRQRPARISISPTEDKNGTHSQHPTTPNSKALPQLPRLIPPSPLSASFERSLSLSEHTVSEVSFATLAVPASPITNPVTNQILPSAEDFSFRQQRSSLVTIQSGSEESTFSRRPGSISTLAFGNLKSGSGNETYEISLDSDKDSSSNYLRGYEGDYDSASAESSSEGEVDFAKYYERRVSEDLQHVQQTYRASRHRHNFNIEKSKETGTWNQSPRQYRRRTLPMDRTRGTSYYYSSGDEHVRYLEEVEIIDLRAETQVSYTLLLVTIQKTAVQRRSWISRPFYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1E8</accession>
    <name>A0ABQ8V1E8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_730212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="66" mass="7650" checksum="B8EBDB8A20EEE42C" modified="2025-10-08" version="1" fragment="single">MLHIPVNVSTMGPLWCYWNFPTERFCGAIVRAVSSRKYPYTSMASRLRDVAQLNQIKLVYGLTREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1G2</accession>
    <name>A0ABQ8V1G2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_927117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF108">
        <property type="entry name" value="PROTEIN CNPPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="89"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="347" mass="38368" checksum="B5D2FA1A5FEBB61F" modified="2025-10-08" version="1">MASVQKPFSTSTSHLASRSKHSVNLNSSVSRPEAMVNPPKQSIPAPVQSKTYYGQEAISRLCARFITHLFGCPERPPNQSGWHVELPYYIAYAIYRTKLPECVVFSALALLQRLKSRFPSAKGSSGHRLFISAFMIASKVMCDDTYSNKSWSVVAQGMFTVREVNQMEREMCGYLDWELTVEGEILTPFQARVTQDFSPLHGPYPIYSLQDVSKHAPKATASKPNSPAPSPDSLNPHFPSFSQRHPSPAKTPTATAPIPMSRSSSTRFERLHVAIKTPSPSYSNSTSPASSISPQTPVGGEDFYTQIQDFTTTPLPEFSIKEKTIAGWPVNHSLKNDIFARAVPAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1H1</accession>
    <name>A0ABQ8V1H1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_854981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="1">
        <location>
            <begin position="142"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="29396" checksum="232B30A2FF581E27" modified="2025-10-08" version="1">MMHSNTIRDYSSPYHQRHRPLVRRYTLSDSELSLPSVRLNRPESFTPSLPSSPYVHRASGHVITTAPPFIPFPGTPPPFAPPALHYSISPYAPIPLPSQSSVGEPFSLHPLLQTSSKHISNTSHTYSSASTSTAVSTTVLDLDLSSSPDAIHSTLMIAATAGIFDPATQPPLPSMTVTHPLLPWFITVHRYLSEHVTVLDVLHTICTDLNKRVERRRSQRHERNGNGLDAWEGRQRIEFLQGRYRFRGLRGIQSGEDVWELVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1P7</accession>
    <name>A0ABQ8V1P7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_925080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4469634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="423" mass="46125" checksum="675077C3D4A2BEDE" modified="2025-10-08" version="1">MLLAGHVNAICPMASKIITARTTRNDTYHQAYPQSTDKRTASVSFDAASQYVSTMGVHAFVPPGLGDFRGPCPGLNAMANHGYIPHNGIATINEFIQGTYEVFGMGRDLALFLGVYGVVMDGDVLSLSFSIGKGGNSILGLLPQNGLTGSHNNYEGDVSPTRGDLFEYDNNHELQISQFLQLYNLQSNVSDPSQVNYDIDLLTSFRLSRFQQSIEKNPYFFNGPISGVLVQPAAYQFIFRFMANKSEEYPEGRLSRDVLKSFFSITGLEHNLVYTPGQERIPDNWYKRAIGDEYAITSLFLETTTHALAHPEFLSVGGNTGHVNTFTGVDFANLTGGVFSASTLLEGNNLGCFVLQAAVMVLPTGVAGLLEGVLDELAEVVNPLLQAWDCPELTQMDVSLLERFPGYSRYPGNGILASLNSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1S2</accession>
    <name>A0ABQ8V1S2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Maltose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_891685</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF53">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="58"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4464390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="552" mass="60993" checksum="06C90B45C02DACF6" modified="2025-10-08" version="1">MSQYGIHDAPGNVIVADNNEILRKLNANTISDAAKADEIEHKMTLREAFKTHKKAIFWSMALSGALIMEGYDVVVIGSFYGQPNFTKRFGIVAPGTATGYAIPAAWQSGLSNGSSAGGIIGLLINGWAADRYGPKIVMMTSIVALTCFIFIPVFAQSLTTLVIGEVLCGIPWGVFQTLTTAYASEVCPIQLRGYLTAYVNLCWGVGILLSSGVVTATLNVDSDWSWRLPFVVQWVWVIPLFMIVFFSPPSPWWLVRRGRLDDAEKSVRRLTNPEYVSDNDIKNTVAMMVHTNELETQAQAGTTYIQCFTKTDRRRTEIVMMTFAMQLLSGENLIGQGVQFLQSAGVGTQLSFDLNMVLNSMFIIGTIVSWGLLTHFGRRTLYTAGMGCMAVVLFVIGGLGFISSNNATMTVGGLLIALNFIYNCTLGPLCYTIIGEVSSTRLRQKSIALSRIAYQIMNIICGIIVPRMINTTAWNWGAKSGLFWGGSALLSTLYCLLRLPETKHRSYGELDLLFENKVPAWRFKSTKVNQFGMHHDDTKKHIDSKEDIKHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V223</accession>
    <name>A0ABQ8V223_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_777442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28678" checksum="6232B1FAC720FD70" modified="2025-10-08" version="1" fragment="single">TLTQIQNLAVTLEDVGRNVEALNLEQSLLETSKRVLGEEHPDTLIRMGNLARTFWDLNRKSDALELEQYLLVTQKRVLGEEHPDTLRSMQNLSSTFRHLNRCNEALNLQQPLVETSKRVLGEEHPDTLNRMYNMVKTFRQLGRYNEALDLQQSLLEISKKVMGEEHRDTLFEIQDLAQTFWDLGRQSDALELAQTLPPALRNFLDKETHINPPVGNHNLLRMKKKIWKAVKDTGLHVRQSLRKIVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2B7</accession>
    <name>A0ABQ8V2B7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_858066</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF50">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="70"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4465722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="34265" checksum="BC938243B1EC8326" modified="2025-10-08" version="1">MLEVAGENLQSSVDTGVIDSSFTTESAYILPSDEPERQRLNEQSRFMTKAVFGGRLISAPSLTISPGDEILESATGTGIWLLDLAHQLPLTISLTGIDISTRLFPKPTTYPSNITFSSQSITDLPPSWSNRFTLINQRLLTGALSKPQWIQALTEIYRVLKPGGWIQFMETGPTPNAYSGAKMKRMVDSWALLYRARGLVPEIQDVLGQLISETGFIEMQKHIIPLPLSPRRDSSSLSDSELDHYEEHKKNIIGFFVAAKQPFLMAGLFKGEVEFDQALEEMREEWDGSEGCWWEWAIFYAKKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2C4</accession>
    <name>A0ABQ8V2C4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="11762" checksum="80BB29C2FA369A3D" modified="2025-10-08" version="1">MSKASYHSEGTSALHPVPLSLENENREGENQEQPSRSGGNTDDREQTKELLSPKSEKYFKATSLKTYRGYKVSKGGGSNGTSPEIKSREERNQKQPSRSGSIAGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Y8</accession>
    <name>A0ABQ8V2Y8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ring box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_852311</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="58"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4470064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="13055" checksum="96F381BEE95310C4" modified="2025-10-08" version="1">MSEAMDVDTPVKKEPKEGKVDGGKARFEVKKWNAVSLWAWDIVVENCAICRNHIMDLCIECQANQVSATSEECTAAWGICNHAFHFHCISRWLKTRNVCPLDNREWELQRYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V313</accession>
    <name>A0ABQ8V313_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_870559</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040153">
        <property type="entry name" value="Rcf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018:SF3">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="7">
        <location>
            <begin position="91"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4471652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="24362" checksum="639C877FCF37F7A7" modified="2025-10-08" version="1">MKVDVTEEQLEGHSKAVRRGAIEGTVAGLLFSGAVSYFAHRRMPAYKTLPLSLKALGPVILIAPLLSIQAERRALEYDESQWTGEGLKILNEKERKVIEKWEAMTPRQKLGDWASRHEYSLIMGSWALSLGVAGAIISRDKYQTPAQKVVQARMWAQGLTIGILIAAGALKHSQRNEAADRHVDHSWQDVLAQQERTREVEEQVKPGLSAATRRSVSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3B1</accession>
    <name>A0ABQ8V3B1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_926245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000118">
        <property type="protein sequence ID" value="KAJ4466075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4466075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="717" mass="80964" checksum="6922D04642B2539F" modified="2025-10-08" version="1">MSNNSYTCSGCGQNYNRSSDLIQHLEKTRRPRCQEAHEVFKQAIHHGRFMLVDPLIHNHSQFSSSSSEAHLTSQDQEDRENEGDDPIHPFQGDFFGNDYSNEEFPGFDDDCEDDENGNEETEADLDPKLEPTWEPEREPASVLQEYGEQDTSVETGVDDDDEEIHIEQFGGQAGAIIVEHGEEQTLPIFHDSKDGFLHYDAHIPGIKENKWAPFASRMDWEIARWAKLRGTGSTAFSELLAIDGVSEALQLSYKNSDELNSIIDTKLPAQRPAFVHQKVVIAGEALDLYKRPVMECIQALYGSPEHAHYLCLTPERHYSDALRGQKQLEKDKPGATIVPVILSSDKTQITLFRNKSAYPVYLTIGNLPKEIRRKPSQQGQILLAYLPTSRLQHITVKAARKWSIANLFHACMGDLLAPLREAGVNGVVLSSGDGIRRHCHPILAAYTGDYPEQMLATCSYYGTSPVCTVSKDQLGDYPCSAELRDPVKAVQAAKLINTAEWTKYCSDADMKPIQHPFWEDLPYTDIFRSITPDILHQMYQGVMKHLIVWITTIVGADEVDARVRRLPARHGIRHFHKGITTLSRVSGTEHKQMCTFLLALVTDIPRKTTSQSNRFLIATHALLDFLYLSCYPIHSDESLTMVETSLSTFHANKDIFIELGAREHFNFPKIHYLCHFVPGFKLFGTSDNYNTEMLRSCTPRNRARGHTVSKCGIRMGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3G3</accession>
    <name>A0ABQ8V3G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_776352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045469">
        <property type="entry name" value="Nis1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19271">
        <property type="entry name" value="Nis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046183025" evidence="1">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="147" mass="15497" checksum="D11534A86A04BF18" modified="2025-10-08" version="1">MKLIFPTTLRVYAAFALTHMALAQNVFIGQPANGSTVSAGSNVTVRIDRPDTLSGSTEVALVMGIWPCNNFPCPGPSNIIGTILYNGPYKPQFSVPSNSLPPHENFTVSIPEGFVKGVTQFGVAHVALIGAGQAPFLETLNATLVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V421</accession>
    <name>A0ABQ8V421_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_850332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021842">
        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF3">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045436513" description="C2H2-type domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="677"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4471906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="996" mass="113891" checksum="30122F6A68DD2E72" modified="2025-10-08" version="1">MGGFGYLSVSFFPSLTMAATSGLAYKRKRSNGEVLQERLWNNPVLKAHFDSSRDVHHYKKLTRPTIRNHDLVKEHYRQFTAYLQQLFDEGKSEKPPQAPEIVIGTPLPTLEYMKDFLCYLVSALQGRDTSTFIRYETLRGYMYTFLALWPRYVNVHPTTAIRYQLNAYIQSDELKTSVNLSTKIRDLKHVEPQCLQILTETLHSASNIFRSHRTQLQIAFLILFSAASAARPGSIVESGCYCGSNEALTWGDLDFYLIPDDEDPAHPSLVVDIQLNLVKGYRDVDHRYQKILFTLEIRKEHRMTCIVLPLLGLAFQDSVFAHFHSVDSLLCPERPPTTRVKLLLRNEVMNLLVFRKEEQGGISDTEAVTHGSWLSHLNKLSIVAGFPKPLTPYDLRASQGNKADVELGETARKTLMLHDPKSQVYFNKYKSKTITADLSAVSNRRNQDQNKVELFWQTITVSSGRDTNAPTDLMLKERENLLNEPELVKLQNEKDKATNKIRQLLANEQSEEVKVQIAELRRIAAKAYNTHRVLYWGELCLRIKQARQRFFDEASVRQMLSPSEPILFKGLMAGNSNDSKYRIESSFLSLVNDLDTGDPVSDYCTLVNILISQPERILYHKFYPGEKPDDENKCPHCSQILTNLPSTTKPGEHVHHCTRKVLSEKATAQVQAQFTPQECKYGHCSKFFNQRSEFITHLIKTHFRKMYTHCKWQISPGVTCDAEDVEDWRAHFSELHGFNLDESVLTEYCTICGIWLYDIAGDRQELNNHHLAHYADLFDSFSSRPLEGTSVSLLPVGIIETEKYIEYTPGTGFNGQLPEFHGHVSDNIALVPGFCPSCVFNEDLPMRKRMHQFIGLNQLMTHFNTVHQPHFSESENLCPVPSCGHHRFAEQELLIHLIKFHRIPLAGSGKHSKVKCLLLPSPDRKPLTHKRRKRSEGFRCIGCSVVVSDINKHLQRKQTTEQAKHCVYTAKYSIVTNGERGPVQIWTAPSLSESQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4M4</accession>
    <name>A0ABQ8V4M4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydrolipoyllysine-residue succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_800647</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="53"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="128"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="141"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4474144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="434" mass="47124" checksum="C492FAB54882D14D" modified="2025-10-08" version="1">MLSKQITAVARGKGVLGARSIHGGTALTMSRGWKTASANIKRAQFHSTNLLQAETVKVPQMAESITEGTLKSWSKQVGDSVAADEEVATIETDKIDVSVNAPSAGTIKELLANEEDTVAVGQDLFVFEPGEVSESSPTPPPKEDSKEDKPKEEKSTEEKPKEDEPKKPEPSEKPAPPPPESKPPKKEAPKPAEPKSAAPVAGSRNETRVKMNRMRLRIAERLKESQNAAASLTTFNEIDMSSLMDMRKRYKDAVLKEHDVKLGFMSAFAKACSLALKEIPAANAYIDGDEIVYHDFVDLSVAVATPKGLVTPVVRNAEGMNFVEIEKEIAALGKKARDGKLTLEDMAGGTFTISNGGVFGSLYGTPIINLPQTAVLGMHAIKEKPVVVDGQIVIRPIMIVALTYDHRMLDGREAVTFLVRVKEYLEDPRKMLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Q6</accession>
    <name>A0ABQ8V5Q6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-rRNA-processing protein PNO1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_911453</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22391">
        <property type="entry name" value="KH-I_PNO1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055212">
        <property type="entry name" value="KH-I_PNO1_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="9">
        <location>
            <begin position="181"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4475848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="277" mass="30364" checksum="012AB947CFD5EE13" modified="2025-10-08" version="1">MVVASSQAQPSTSAPSVPHRKNRRKMTKKATFSSVDADADQNMEEHHPVTDALPSNGEDDDDIMIDDDENSASLPKASAAPAFAPVSADALQTTLKSETRRIPIPPHRMTPLKKDWINIFGPLTEILGLQVRMNVQRRTVEARTSKHTKDIGALQKGADFVKAYALGFDVNDAIALLRLDDLYLDSFEIKDVKSLQGDHLSRAIGRIAGQDGKTKFTIENASRTRIVLADTKIHIMGSFQNIKIARDAIVSLILGSPPGKVYAGLRTVSSRMRQRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V606</accession>
    <name>A0ABQ8V606_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine protease inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_773976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0722">Serine protease inhibitor</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="16330" checksum="2068C18069E8BA2D" modified="2025-10-08" version="1">MALETGLYTIKNGEKLVGRALAEDLSLLPKRIILTESERTSIWAIEKSDKDNEYLLISFGSPTTHIENHVFALLINQEQATKWTIKAVPQHGENAYVISSSDGKGWVAPKELKEQIEYRILIVGPSLPPRYPPNEVFQITKLEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V607</accession>
    <name>A0ABQ8V607_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_549551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="90" mass="10428" checksum="2F35E631A7FD13FF" modified="2025-10-08" version="1">MKLSSSSICMHVLGIRYVFRSALIRSTSRSALIRSASRSLYQLFWSQACSYMEKKLLNCKALQKNNDDLFSGWGLFGLPMKMLEDMRSHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6I0</accession>
    <name>A0ABQ8V6I0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High affinity methionine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_773361</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF353">
        <property type="entry name" value="METHIONINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4476784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="564" mass="62218" checksum="E279E9A48A3BA54C" modified="2025-10-08" version="1">MVTGSDETLNQSRLDPIVEEQQSRITVDDDTFGAPVETVSPLGYHVDWISVIFLNVSRIIGVGVFVTPATILRGVGSVGLSMIYWVIGFLFSAASLCVYLEYLCYYPQRSGGIVTYLEKAFPRPRLMAPFLYACLFCTLSTSSAACIVFAEYILLALQYDITKWNVRGVAVGLSTAMTLICILSTKWSLHFSNAIGMIKVLALVLIAITGLVVLCGGISHVPNPGANFSQPFYGTSNNVNGLVSALLKIRFSYVGWESVFSMVNEVKDPIPTLKKFAPLSLGVVFALYMLVNIAYFATVPLEKIKSSNEMIANLFFETIFPSSPDSTNIALTVLQVLVAISSLGSVIAATISASRIIRESGRQGLLPYPQMWASTKPFNTPLAAYLLRWTVTSVLIVIPPPGDAFNFIVDLQYYPESIYAFLLIIGLFLIRRRRRAVGAPSIPFRAWTFVAVFALIVNLMIMIIPWVPPEGGIYAGDVSFFYATYCIAGLGVIALSCVIYYFWYVYFPHRGGYRIRQVTEKLSDGAQTSKIVKVPIEVLEEWDAAHVDDLEHLAGNEERGEDQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6P1</accession>
    <name>A0ABQ8V6P1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="50551" checksum="9448F97482222587" modified="2025-10-08" version="1">MSTLRVQLIFHNLDLRDLFLLASTCRRYHRLITRYLSTQYRLDRFLLNFFNTDEFTTLNGYMARGLVISGDGAKRFLLREMHSLTLTLHAPLTDCEQITQWLLIIGYTYLPQHNHLLCLKSDIARTKIYLASHHDTDPECRTWFFTRRNCSVKFIAAEHTIVADILNGTSWTSMMNIITHSHLYCLFPKSTLVDHSDYFICPIVKQTADPSQRDVVRQFRQRRNEHSLLPPLDQVLSPDGELSFQTKRSFGDGKCLTIPTYIAKRLRSLATSTEDGIRSHEWKIVYHVNWMSMSFEVVINQSTSAAYCVTLDNANSIQIPPTADITSVSQHHSNIISQLLQTIICPSLPITPSVNNVIDAFTLYRLFNILYRTRQDWDFTSGAVVALHLCVHVVLRNGHKSSFLCSLNSDLDELLYEHINLRFIWSYIKNEDDGPCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7K5</accession>
    <name>A0ABQ8V7K5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_772578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26750" checksum="012CFBB78A96508A" modified="2025-10-08" version="1">MLPPSEAEAQGLSFVLLEPGSNVSEAEYHDWYDNEHAPARLTIPTFLNAARFKAVDGQKPTYLTLYDLSESSVADGPEYQALKDNGSERDKRLLATVQYLNRRAYSSIYNSTLTTASASDFPPKFIFVVGLDVKTEGEADFNKFYNEEHIPMISKIPGWLRSRRYILSNSAIRGSIDTEVTVCKYLVIHDFSESGYMDTSEMKAAASTPWVKEVLKSIVRREARHFTLLKDYKRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7M3</accession>
    <name>A0ABQ8V7M3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol polyphosphate-related phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_514420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="178"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="771"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4478601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="905" mass="100385" checksum="43DEB2EF2F24EEEA" modified="2025-10-08" version="1">MTYNIEISRRPQLTVRTREPQQSVISRLQGLFPTSPNVLSGIPPSANDDATLRPPQSSTTAPKFLKIRILTWNMHDSVPKGDLEELLGKVPPYTSSSSPTSSSSSPEFPQLDADAGHPYHLILVAGQECPSTSGMPMGLGAGFKLKEDRDKDKEEKPRSSKPSHGQESLKYKKSSGTDEYTQETATHNSGWTSIVEDWLCHGGSMARAASPTTSDTGVHKPLSPRTALTVKDSTAKKGPYQLLCKERLLGIYLAMYVHRDLKPLVESTSKAFVPAGLLGGRWGNKGGVGISAKIYGRSFLFLNCHLAAQIDKANLHDRLNNFNKIKTELSVDDFLSSDDPRVMAEDLTDKFDYTFVFGDLNFRLDISRLHADWLISRQDYAQALAFDQLKNLMDHGRAFVGFSEGVIMFPPTFKYDVMRTLKRNKHRSGHRVGQLRYPHEKARRLTEVDEKELDTAEHDLRINDEDGDQESDGEDEDREEDPDAEGEGEEESTSLASSIWTSLHSKAITEQQPDESYFSSTPNMMRSASAPGSRASLSLAAHKAKTKWRSLLSPTAPSSPTKRLKKPSFLEQQQNLLTRLQKRKTQQSVEDLKLGGSEPEISPDAASSHTAQRSRVNSSKSQVPSDDDDVSQEDKGVYDSSHKRRVPGWCDRILFKSTVQPNPEVEADVAENSVRTRTKMGQFFANAFRPLSARSRRESYSSLSSLVHSVASSVSNHNSATPTPRGDSTPSSVIHSADLLEQVAPFSRFVYGNSSTLPFDTSPSEVITPAANQLPSHNEHGFSKVKRSFSSSSRKQSKTNILERNPRRASTSAPPVPPDSSPYNAPREHVSTPSKWRFFPFLYHNSTSSSSTDIISTPPTDISINVPRRGDLVCLSYDTLNDRSMRRLEGRSDHRPVIGSYAVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Y1</accession>
    <name>A0ABQ8V7Y1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sin3 associated polypeptide p18-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_922640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.550">
        <property type="entry name" value="ASAP complex, SAP18 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010516">
        <property type="entry name" value="SAP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042534">
        <property type="entry name" value="SAP18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082:SF0">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06487">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="31013" checksum="90F6631D739E4934" modified="2025-10-08" version="1">MEVDNASPTGQSAVVRDKTAPFLIRTFVKIGSFHRLSLFEDATLPTTDEQQIFTWKDATLSEVLTTLRETAPHVPEYRHPLARFAFRTVYADSGNKGRFSQKELGLVYSRDILGEPGTLTSIAPRLLEEADNENREQTHREKEERTLDELRFVPGDFLLLAVLLPKNVTMGSDLSIKGSANAAAQNGPGWKTGGDGGWGKPPAPSIGGPGLGRGGGHWRGDSNGRGRGGGRGGVRGDDRDDRIPPPRSPRRAGGRGWGDRGGRGGRRSPRSRSRSPPRRRGPAYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V920</accession>
    <name>A0ABQ8V920_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_775015</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12932">
        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 central conserved" evidence="10">
        <location>
            <begin position="123"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="9">
        <location>
            <begin position="330"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="660"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="864"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="956"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="686"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="718"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="752"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="974"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4474542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1081" mass="113773" checksum="C513879D53313C6E" modified="2025-10-08" version="1">MISSPPPPRPPPQTRGSYDVNPYLPNSKPVTPPHNRSMSNGSILSTLSEDPYAPSKFQSGESYTSRYNNLDNDQASPNPGSASSGISSLGPPQDIKAPTYTPYAPSPSLLGTNDPLGRAGARVPVFSFGFGGKFVTCFHGADKMNTGFDVALASRNSTGVEIRALNKIIPNSALNLSSVSFPGPLFSDPGSPTIGLVRPGAAAQAKTKKARVVKYLEDRVEEFSQGLGYITTGSEDQGRTESKLILFKILKVLVENDGKLSGTPSMDAAVRAALVPQTGADPNGVESSNFTSVADLQGTDGTLMGLSNPPSSGETPISVTTLRPSALNKIEGFLLRGERRQAYHYALDQKLWSHAMIIASGIDKEAWQEVVNEFLKTELGTQPPSMGPSNGRESLRVVYSLLSGQGAKAVHQLVPKTSLSNPAAVLLAPMTVSATPMTPNFSVPMPAANIPAESLSKWAEIVAMMLSSTVSAETSATMTALGDQLAGNGWTEAAHVCYLLSPQTSTVAGSQHPSARIVLLGARNPQLSSNFLSDPDPIILSEIHEFALSLAPVSKGQEAFGGLPHLQVYRFIRAVGLAELGEVSISNRYCEAITASMNRPSAYYTNVMLEQLKGLSDRIIGVTQADKGGSWMGSKLAKPSLDGLGGWLEGRFAKLVTGDMESPTATEHHREKTDERGFVGPFSHYSTISSTTTSTTPSPQSSVVNLNAYAPPPPRTGSALSTRSLAPPNGSTERASSAMDHSRQRLQPSAPRVTSANASTTTFSQAQSHSFGQATAARYPASPNDLLTPRPALGTTEEDEGQEVTWWGSGNAATPTTATFVPLSGNALTPTVDGFVSFMDNHDHSIGATYQAKSDGSTIHNAEEEEEDLGFGNSKPKPKSASDDANESGVAKTAEPKAAPARPDINPSQAQAAPSSGSWLSRLWKRESTPGPVKASLGEESSFYYDKELKKWVNKKVGSEDVSKPATPPPPPSRAQTTSPGGVQRPASGPPSAGMRPPSAGPPPPRAASAMDNPPSAGKPPMRVRSNLVPSDEGGPGSAPSTPTGSRLAPPGPPPGRPRSQASKRNVRSRYVDVFQQESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9B8</accession>
    <name>A0ABQ8V9B8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053221">
        <property type="entry name" value="Burnettramic_acid_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887">
        <property type="entry name" value="CHROMOSOME 21, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="483" mass="52918" checksum="3BD00D88448F7F2C" modified="2025-10-08" version="1">MSMPGLSVEEEASTETHPGIQLAQDADLLIRTYVPSSLSLNQPYTGPPIPLPLCIPQVGVSPDEHSTFARGYNEVLNDTGIPQDVLLNFIDGLNMAIIASPPLRVVGTVGKMTEKIRPHHWAMIAGAIINTAAGVAIHVLAKTLTDRYLRAANLNLFKPRGLSVRICTTSAMLALLDSSETKLSSRLNKFGRGVGSVLLKIPLPVVNPIASTIIHAISDKPPAISPSGREGDPIKNSVLRRRVAMTEGFALSLNIDDIPPPVKPDGVMDTMASWGIRFDTAIEKFSEKNNERRRRALQSIREANIEQPSNSIRLLETGSPTSSSASLPRPPSNTGRSGISISSASSTGVKNMASSAFNTVNDWRLQREVYFEQQNTVLRNSRLRNVGLLGHKKSRMEQKVADADLLEHWGTEKILWVVIMASDKDEEIENIGIAEDPADEEQIDDRTWRERMAVERDEMELEDLQKLQQQGTHTSVHAGEGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA30</accession>
    <name>A0ABQ8VA30_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_770565</name>
        <name evidence="2" type="ORF">C8R41DRAFT_783063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="225" mass="26496" checksum="727E0BEB004E832C" modified="2025-10-08" version="1">MEENYGVERGSYIWGRSVHNIRIERLWRDVTQGFGLKWYNFFFSLEVELGLLPDIDEHIWLLHYLFLPSINQDAHEWAGSWNSHNLQLQNERDRSPQDMFFFGAIQEGLRGPTGAPTHLEEHVEHVATYGVDWQDLGDATLLRHHNENNPHELEDLDHRRTRQPPHLSLVEVPAFNCPFESEEQLEIFNNALLAMPEYHSRDMTQRKSLWVQALDLLELLLPHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBC0</accession>
    <name>A0ABQ8VBC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_543226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="27"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="199" mass="22499" checksum="21BEF46F685F026B" modified="2025-10-08" version="1">MADAAENTGAKDVQPIRQSEIFNAADADVVIRSCDNVEFRLHKKNLEFLSGSFPPADTEVNPNEIVRLSESGETLEILFQFMYPRRFPSLDNMKIDPLIELAGTAEKYEIFALIHVCELHLRSFMQQYPGKILKFAAQYDHRELVKEVAPILVPSLPLSELSDLLPAHLYKPWVSRSCSKYNKSSTQVSDSRVSIENIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBS2</accession>
    <name>A0ABQ8VBS2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_842296</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17870">
        <property type="entry name" value="GPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030230">
        <property type="entry name" value="Gpn1/Npa3/XAB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF8">
        <property type="entry name" value="GPN-LOOP GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4480779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="41233" checksum="A0442EF1C5AC4440" modified="2025-10-08" version="1">MSSNSDAPTKKKAMAIVTIGMAGAGKSTFVQRINAYLHSKDSPPYVLNLDPAVAFLPFEANIDIRDTVNYKEVMKQYNLGPNGGILTALNLFTTKFDQVLSLVEKRSHSIDYVILDTPGQIEIFTWSASGAIITDAIASSLPTVVAYIIDTPRASAPATFMSNMLYACSILYKTKLPFILVFNKTDVQPHDFALEWMHDFEAFQEALATHGGTRDAEGEPTYMNSLMNSMSLVLDEFYKHLKAVGVSSVTGDGIKEFFDAVEASREEYETQYVPDLERARATREKALQDAKSDSMDRMMKDLEVDRAQHPEAAAQDRWDPEEENEEGEDEDVDINIIDRSEERWPGEYIDVTRAQRHGDEGIHWPRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBZ0</accession>
    <name>A0ABQ8VBZ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_418942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="22221" checksum="01835ED3DB054BF6" modified="2025-10-08" version="1">MMCCDSILNCWPVQQNFPPLRVVINCLSLLATTGKAHYYQTHTQSTIRRGHALDLAAEIPPQTFEYSIPPILARPSVTKDNQLIGHGTSQLLLLPRSKSSGIHCACRTSHRTSKTKDMKNPGSSYDACTPKTLYELLPACSCSRYHYTSCLLRKLRRLPTQPPSIEYPTLQSPKRIRQTYGTYSRTLRSGSVRITHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD40</accession>
    <name>A0ABQ8VD40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PUA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_514584</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF27">
        <property type="entry name" value="OS04G0289800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="22"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4478603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="253" mass="28710" checksum="F6F5B9DD93E766CD" modified="2025-10-08" version="1">MPDPRNIFKNRYKKQTKTYGYGKVAGIEVGTILSSRQECSDRGLHGPTQAGIHGNATYGAYSVVLSGGYEDDEDNGERVWYTGEGGRKNGGGPQIADQDWKNKNNRSLKISCAPDRYPIRVIRGHTLHSRYAPSWGYRYDGLYRVAKAIQVRGKAGKLLCKFLFVVRIMRFHLIYTYGIISDKKGNLHSHNRPQDRPPHYTHRGPSSTPIFILAPTMRARPRRSNPLLRGAQVLPPLMVPIFRTTEDRTTNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDA6</accession>
    <name>A0ABQ8VDA6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_767158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="44446" checksum="69A427446BECF9FB" modified="2025-10-08" version="1">MSTARERLALEFPDESPDNEELWEFEIFWRDHYDWLKNRGYLLRPRYRPGWVASWIGTTKEAFRCEDNQVQPLFPLNLDAIRVADGRPVMLRRADPPSISDELEIGRLVSSKEISSDPQNHCVPIYESLELPRANEVGRKCIVVMPFLVPWDEVGFVTVGEVVDFCDQVFEGLQFMHKMSVAHNDAKTTNIMMEWSPLYRNPPHAMDSSMRMDWEGPSKPRNRTLCPVKYHLIDWDLSKQYDTIRGVTLRMPGYGGDQSVPEFKRKEPCNPFSVDVYCLGNVIRQKFIEVHSIRNLEFLQELVFDMTHDDPQKRPTMDEVVARFGKIRKGLSWWKLRSRVSDRTIPLIFHLLYSPIHWSIQLTYILRRIPAIPDCYHSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDN0</accession>
    <name>A0ABQ8VDN0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DOPA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_734470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423:SF2">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="20303" checksum="43EDA6AC6E5DB00F" modified="2025-10-08" version="1" fragment="single">MPSHLKMRPLPYSSPLEGYENPPPLPTGFTSDGRSLDNFIPGQEYKRSKAYDEFIDPIDNKGNGFDFHVYYMHTVPTHLEFARKLHERIRREFPELRIYSMEEFPMGPHPTGSFEVDTFNPHETGTLMTWLVVHRGPLSVLIHPNTDDELRSHTEHATWIGERWPVNSDILQHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDT6</accession>
    <name>A0ABQ8VDT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045081429" evidence="1">
        <location>
            <begin position="19"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="163" mass="17743" checksum="D154FA7358D380B1" modified="2025-10-08" version="1">MRLNFVCLVLVLASAAYAGPISNGLCAWFRSKSMPYSFSAHSGHLDSGNANYQVLLEKDKIAKELVQKLFEIGAHVNTFTEQSFIGATTDITRGFDFEVGQNVIRKQDSGPYHGWVKANINFVGDKMVIDENSIGGYLKAAGGKFIFQVGGGKATQEVVLRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDW0</accession>
    <name>A0ABQ8VDW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_834551</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14046">
        <property type="entry name" value="STKc_EIF2AK4_GCN2_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016255">
        <property type="entry name" value="Gcn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024435">
        <property type="entry name" value="HisRS-related_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12745">
        <property type="entry name" value="HGTP_anticodon2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000660">
        <property type="entry name" value="Ser/Thr_PK_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="14">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="204"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="556"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="624"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="646"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="586"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4489793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1575" mass="176826" checksum="C112995A5457AF9D" modified="2025-10-08" version="1">MESTEELQQNELTALKSIYAEDFIEIPPPKAWKGAARLPEFCIRVPHLNPDFAKKICFDLHVIFPKTYPIKTNPTFTIQKPINGLSNEQITKLSHAIHAEAQMHRGSEMVMEIVTFCQDWMTDNVIPATEAPGSLALQMNIRAEDEEKARKQKAEALALEELEKESKHAQELEEQLMLDSARQQVAREREYKARKRASSEATEVPMTNEYPTESFADEIEFQGIRFDTVKYFHPRIECLGVTYAADPVCDDVNATLPLQLHVVTFDTQYYSTTQGRKKLKQLEAEIRRLTAIRHPNIVRTLAVKLYFPNSNSPSRLSILSEQPPALTLEDVLQDCDSLREERASDYLGQILAGLNVIHTADLVHRGIAPRCIGLESRNSQSNSKLIRLFKVGYYTRLVDFHKSNEFRTTLSFNNEEAQIPDAWLSKDVKNESSLLYTRHRDIHSVGIVFMQMLLGLDVIRRFSDAHTAMKLSLISAKFQTLALNMLFPPKKNHISCLSLLADLAETAISDNLRSPTVPITSADLKTPMQLGYGSSPEIEYFRPMGLRHTSRWKEDWEELELLGKGAFGSVVKARNRIDNRIYAVKKVRLRTTQSDKIFREVNALSRLSHRFIVRYYTTWVETSEPSSTAASDDSDNEFDSSDLSNTEDGMTSVPNSLSTRRTTTSTDDGLIFSLDDLDEPGGSRGSFPSIHFSARSSEARIADEDTDSDGDPLALDSLFHPQTARPAPPPLLQRTLYIQMEFVERQTLKERIDEGLSVEEAWRLFQQIVDALAHMSNLGILHRDIKLTNIFIDGNGDCKVGDFGLATSSLAAVDPSDVAPRAVAPQADMTLEVGTRLYIAPEVQSRRRGPTNHSKADMYSLGIVFFEMNYAFSTGSERIFVLERLRKSDVQFPATWDPLRARQREIITWLLQHEPNQRPSATELSQSSLMPPRMEDEYFKGALRLMAKPDSPHLQTVLSALFSNPPKPVRGFLYDHDAELPEYASLNGVVQDRLGTIFRLHGAVDMDPPLLTPMTDGDDKTQAAFVDRHGEVVTLPNNLIVPFARLAAREKVQRIKRYHLSSIYRPSLIPGHPKVWKAGVFDIITPDYLHGPVAAGAEILAVAHDILESFPNLTPTYEVHVSHSDIVSVVVERIPASQRTAVLDVIQHTKSSSSQKKANLLKKGLPRSLIDELDVLTDADDDVDAVMTRLEKINPPLVEQLRSAVDEVKATIQHAVCAGVTQPIFFRPLMLGSYFTHFKDGVLVEVAKKSRRTDILAAGGRYDNLISQFTQPKTKGQASYAFGLQIDVEKISVMLALFQSTSVQPLIKEARSFGFWSPRRCDVYVISYHPGFLQERLEVVAWLWQHGISADLMYESGLQEADQENQVDMCAREGILFTVYPRPRAGRRDMAAFKVKSILKGTEYEVSKADLIGWLQHEIGEQKRIDATTACTPASSRLGGPSVTQLGRSSVVLPPGSADVQLCLPQETKKQRRQVKQMFLDRAYDVSSDLKATFQSSSGMPVVAVDISSSLFDSLTRNATWLVDEEVWKGLIGEFSNTGYAQQVREAVARKKSEGNSWVLLVGVKEERAGLLNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDY8</accession>
    <name>A0ABQ8VDY8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_838768</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040309">
        <property type="entry name" value="Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="269"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="384"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="468"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="554"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="572"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4485126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="603" mass="65796" checksum="08CAE175F97A916D" modified="2025-10-08" version="1">MDAFKLPLGIAQDLLLIQSLVGPSETPPLRIQETNVPEDVIDSSGSEPDSEDEIEAALVGKTDPDGFGSNGTSQITAQVPQESSSSDDHDTSSNSDSDSDSSDSEEVLRKNEAGAKVEDDEEAMMDEEDPGPSATTASYYATKNEIADATITVPDVEEIGSEEYLELVGKIMNIIGNVVIIEGLQTELARGGSDRALDVDTLLVFEDRKVLGYIYETFGPTTQPMYQVKFNSTTYPLDSEKVCISRQVYHVPQRSNFVFMRQIQAMKGSDASNMNDEEPADHELDFSDDEAEAEHRRNLKKKRASSRASSTAPSRQATPALSQARDADMVNEDYFMNNNAYDEIGPYDLNYDTPISRPAPIPYDDPYADEFEVPSASTSIASSISTPFTFHGNDASSLRPQRRSTNQKTNGRDEGHRGRGRGRGNNNHNRGNSSRRGRGGFNDFNRSSSITNNELEWQSNHCPNVSFRSGNGVIPSSSEPQPQFYQQTPVSPMGQWPFQTQTQGMPNYGMPYSPQQQFVQPHINPLFAHHLGMNGMGGGMGMNGGSYGGSIPLANTHSQSPEASGYSGAYASTDGSSYWSSSDQWRVPTQTDGAEPPTSIQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE28</accession>
    <name>A0ABQ8VE28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_835003</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056840">
        <property type="entry name" value="HEAT_IPO9_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF9">
        <property type="entry name" value="IMPORTIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25018">
        <property type="entry name" value="HEAT_IPO9_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="25"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4489173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1034" mass="113209" checksum="4E41FC1D698170A9" modified="2025-10-08" version="1">MPSPSNVAECLAGTLDTNPNVRMAAELKLAEFMAIPETGLALSQLVSAQDADINLRQSASIVLRKFVRERWSPYFQSFKGSAPSTEIKNQIRQAVFHGLSDPARKIRSLSAHTLSSIANCDWPDEYPDLLTSLINLISSNSPESVHGAMQVFTEFIKSDLTEDQILPVLRDLLPVLLSILGSTETQTPLTRSRTVSVFRQCVISLFMVKEQHPQPVKEAISTVLPVWLEAFKVLLNMDPSKDVAEGSNWEGLAVRIQIFKALDTIHTSFPRSIAPYLPELVPASLVHLNTLFTTFDRYYLASTESVPSSSEDETIELPQLITSIMDFVSSVVRAGRAKEWFTGDNAVSLISAIFSYIQMTDDDEENWANNANAFVAQEDDDLAPYSVRVAGLDLLTCLLDRTPAQTTATCHNVIQKVVLTSDQTRTSGKKDWWRPLEAALTAVGSQAETIQECIDDEQESGRNRPIDIESLLSNVIPTILGQSEFPFLQGRGFVFASQYAKLLPVQLAGQYLDAAIHVIEANDASIPIKVSAVKAVQNFCVGSDDNALSPFIPRIAKDLGPFLAVTSEDTLSLVLETLSVVLEVDKGKWMTQELANSLVVAVIDVWTKNNKDPIFLSIFPDIINSLAASDVPGIYATVVKQALPLLCNSISVATADQSYVAGSAIELVSSLVKASTNGLGEGFFPHLAPSLFECLSDVEDRDVLQNGITCLTLIVRKDCGQLLAWRDASGQSGLEHVLRLVARILQAEDESAGLTIGELIIHLLRRAGESVLPVLPELLHAMVTRMLTAKTATFVQSLVVPFAFLINNQRDTVLALLEGMSIQGRTGLDVLIQTWCENAETFQGFWPSRSSTMALTALFASERPSLQALMVKGDIILKSETTNVIMTRSRTRTTPIEFTSVSFPVKAIKILLHEVQSGGEPATMGNTQDFADDVDSDDGDDNWADAGDVTKDSEFEFLSELIGPKGMAFDNDDILDDSDDEDLKGDPISQIDMQGHLVSFLRECAARNTNHFSSVVDQLSAEETLVVRRIVEHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEE0</accession>
    <name>A0ABQ8VEE0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_920262</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="1129"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="757"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1092"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1213"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1375"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1483"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1097"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1213"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1263"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1395"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1425"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1524"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1592"/>
            <end position="1603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4491648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1721" mass="189744" checksum="B9C8785C5CBAE1AB" modified="2025-10-08" version="1">MSSSPSGQPRNPESNDIDAPRLKIKIPNILSSMAIKPAAGSPPMPLRRSSRNHRGSEPSGSEYQQSEKSMMDEEPEAEEEEEEEEVPVIMKTQRGRMIQKKSYVESDGDEDGEGELEVQDDDLLNFKEEVDPPGRRITRGFKRASASAEDTREGLRRSTRSRNLPDFVVPDEGEEEYDDDEADNRPHTRSRLTRNRPSGRSRSRQANGRTSTTKSEDHSRGTGRRRTRATTKKEDDYNPGSSSPHSADADGSDDDNAPGTDDLDLELEPPPEPEPEPEDDVSGPDGTGNGKPYALRQRQRINYAIPPPLEDLSRPPAHRSNNANNRLYNRAGGGRGVGGGYHGARRKGGLGWSASGAELGKWMGLPADDSDSDVPTRTPRKPFGGIGMAGGFEGAVAGGGGLLSGDLAAAGTPSNLGKVDDSTLADADPLGVNVNVTFDEIGGLDDHINSLKEMTVLPLLYPEVFQQFNVTPPRGVLFHGPPGTGKTLLARALAASCRSNGKQITFFMRKGADALSKWVGEAERQLRLLFSQARSSAPSIIFFDEIDGLAPVRSSKQDQIHASIVSTLLALMDGMDGRGQVVVIGATNRPDAIDPALRRPGRFDREFFFPLPDLIARERILSIMTKGWKGWGSGEEDPRVKARVNGLAELTKGYGGADLRALCTEAALNAIQRKYPQIYKSEDRLVLQPETISVALRDFMVAIKKLVPSSARSSSSAAAPLPTQLVPLLHDSLQKAKDILGRVLPLEKKLTALEEAEFEDYHDNDEGNRNDGEGKDYGGELEREMRLQSMEVLRIHRPRLILHGQIGMGQSYVGAALLHHLEGYHVQSLELGTLLGDSARTTEAALVQLFVEAKRHSPSVIYIPSLVGWCAAISETARATVRAMLDTLAPTDSILLLAIVDGKFSTLPRDVRAWFGPTAIKDNSVEILAPSPNQRSTFFEPLIDDIKRPPNKFADGMGAKRKKRVLEALPIAPPLEPRKPTEKELAVQEENDQKTITILRYRLGPIISELKRKFKRFTKRAQEEYKVEFDLNEQMAAAPSSAQSDPVVQTVVSTIAIMSDGAMDVVQDTIQTQPQQDPSFNGQVNGAEVPPAGIDIDSSQTQSHPQSLDAVQTTPHLPSPPPQPSLYDMDLEKMHELLYKDRYLTPEEFLADVRKIVHNAAMYSHRDPDRHYKAQAMLTATEVSMQDNFDLILREECERMAGRVRKRRMEYKMKRKEEKEKEKEKEKEKEGVEAQAPPFLNGTRRSARNNGQRPELAITDPVALERKLKRQREGGDSAVGDAGPGGEMDQDGARDAKRSRTFGDPNDRDPLDIITPITTPPRPGGVRFAPSVGSVNPDHTHPPQYHSQYQPPTFDRFQQQYGSMNMNINEFQPSIGLMGQSSSSSHLQPPFYNPSIASGSNTHPYPRQNSFEHGLINEQSGSFPSQQTAYSQQSFSYSSQQDFSNQQSSFPQQRFHPQSSFQDVTFQPQPQYHQQVPFPLQQQQEPPFYPQRPSSSYHPQLLPPPGPTGYQSSSNPTPVPYIMQNDNSMSVDQPQPPSTPRGGGVAMLLNPVHPGEERERTVSARPSPAPQNSHQPSAPVPGDDGNPFLTVSDATRNVPNRKSASPLPQIPAHPTSILKSPAPPEKAASPMPIIERTPTPLPNFHVDTLLLEQLHASLREITFGLTIEELEQLRATCLGCVWRHRTEWDRDALVRELQDVVSDFVAEISANANASDLDESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEK6</accession>
    <name>A0ABQ8VEK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADP-ribosylation factor family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_833846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04154">
        <property type="entry name" value="Arl2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045873">
        <property type="entry name" value="Arl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="187" mass="21334" checksum="DCF1ACDC1DF30AE8" modified="2025-10-08" version="1">MGLLTIIRKNRMKEKEMRILFLGLDNAGKTTILKKLNGEDIMNTSPTLGFNIKTFVHGKYTLNIWDVGGQRTLRPYWRNYFEQTDALVWVVDSGDRMRMSDCRDELNSLLLEDRLAGASLLVFANKWDLQGSMNDSQIRDALDLSSIKSHHWKILSCSAVTGENLVDGLDWVVDDVAKRLYYSSTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEQ5</accession>
    <name>A0ABQ8VEQ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-C2HC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_833105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="17204" checksum="1B30BDF8957CE26C" modified="2025-10-08" version="1">MKESREDETVVILKVKTHLAYIPEEILRLRPQLPATKDTPFPITLTTPGLTIRDVRFAMLIDEMFRNEYLKTGRGLDPTQPSSLDYPSAQHMASNIFRQGFCRCCGLPHPLHQCSKRKHYPPAGNCSVCGGNHWVIDCSVLRKKKGKKASVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VES7</accession>
    <name>A0ABQ8VES7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_838473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18041" checksum="8FF33459AA14B500" modified="2025-10-08" version="1">MPLPPKSEPKIFQILIRTHQTTLFFTVPPSTTIGFLKEQTLSALNSGLNEEEDIPPVKEVGDFELCRCRGIKGKDRNADVQREYDILDEPESTIKGIKLANWEVLYLQFKDEEGQPLQIVASDPPIDDEEDVEPQSTVPSSPPVDKGKRKATEYDEEDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFH1</accession>
    <name>A0ABQ8VFH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multicopper oxidase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_832343</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="71"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="217"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="476"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4492390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="597" mass="67058" checksum="E4A4EAD0162AC638" modified="2025-10-08" version="1">MGTRLSAWKYATISALILVALISPSNLILKKPLLAFFSSEEASRFHLSPSSHSLRSESTRTYNFTLAEEVLSPNGVQKTVLTVNGLFPGPTIEVRSGDLLVVNVYNKLSEATSLHWHGIRHPAGNNSQDGAAGVTQCPIPPGANHTYHIHLLSEQYGTFWYHSHQSTQLSDGLFGALIIHPPASLAEKARPHKDELRSERSLRYHRTSQSSSVLDQVMLVGDWYHRSGKEVLDWFQSLRSHGNEPVPDAILNNGLQLFNCSKSIAKIICDPKQGRTPTFRLHPQYQNIIRLINTGSIAEIHISLDFHLFRVIEADGTQIQPVIVKEITIAPGQRYALEVIRADEGKYDGFWLRQRVNYEDFKYPNVALDLESKSIVTYGPRWDLNLPSSQSWSDIKAEERLDPLSLQPLDHIARVLPPADETLMMYVTTMIRTATGNRPFGYVNQTTWKPNLTNPVLARNEFVSSSKELIVPVNVGNTSNSIVLDIIVNNLEDGPHPFHLHGHHFWPLYTYEAVMGAGSYKWERPPTLPTTAPALRDTFVIPAKGHAIFRVRFDTPGMWLFHCHVLVHLQSGMAMIFDVLSDRIPQEDRINAANSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFQ0</accession>
    <name>A0ABQ8VFQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_836834</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="108"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="430"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="445"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4487468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="483" mass="53053" checksum="D42439894CC76EB5" modified="2025-10-08" version="1">MVAKSRPATKKTTAEVRPTKKARIEDSVSRKIKHRTTKTSNEEPTVSVQYKGKQKADQNIVKNLSSAVLPLTFKIVAGSYEKLLYGLEGSTSIENDEVKFHLKPMFIFPAHVSCIKAVAASPGGKWLATGSADEIVKVWDLKRKKEIGGLMHHEGSITTLLFPSRSHLVSASEDGTIGIFHARDWSVLRTLRGHKGHVNSVDVHPSGKVALSVGKDRMLRMWDMMRGRGVASVKLGKEGEIVRWSTDGEMFAVQSGKEIDIYGTDMSLLYSITHPSRLHDIKFCKRAHHDGQVLLASAEDKKVSIYDFLPLPGQPTASDSGDNKESSPKIVAELVGHGNRVKALQTLNISLSSPPPSTLPTTDTSAIRRHPHSTTIVSTVSSDGKINVYDLGHLHEFNAGKISIQEIQPVATYDTKGTRLTCVTLGEGEIGNENVTGKRNRERQEVEEDDDEESAEDEEWGGVGADEEAEEEEGEEDEEEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFW5</accession>
    <name>A0ABQ8VFW5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_981163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="308" mass="34107" checksum="849227078662D94A" modified="2025-10-08" version="1">MSSPLLYSLGLENALLHTQWHGYSEVTATTLLLWDYILTFQSELELIWGRPKNGVTFLFLTNRYLAVVAQLVTTYAHVSSNVTYEVSVFAIAYWLIGTSILQLALTDGIVWLSVCSLYCNTSAVRWPLLGLMITCMLCGVSVVGVVGSHSKGAAQLAPGFKQCTVYTQYHNLWLFWVPLLVYETTTFILVIRLFIQYRRNRKEWTSNLLELLLNDMLLYLAIIFIAFIGNAILFANPDPTLSGILDPPTVVLLSILGNHMLLNLRAESKRAAQGMIYQSGVRDPGTPGPGLGITGTGLETMAFTTATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG60</accession>
    <name>A0ABQ8VG60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="287"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="579" mass="64391" checksum="9F296AFD6B85F7B7" modified="2025-10-08" version="1">MHRSRRRHRQQTPLEETKTSFAIHTDTDGSDEEHMVHDHISKHDSDGDEEEGDDNDNNNNNNIEDELEDCTPPPPPPKRRKNAAGRSDTSEQRMSTRARTNGKPKEPNDAQLRREYEAMKKREARLKKRVQGPYEENVDADSNQDIESEDETRGNIIWGPAARPLETISTTNTVKRIAAKKRKTNRSATSTPHSAVSTSLATSASHSTATSRSTTPSRSTPTSAMPVLSSTCLASPGMPQVNDALSTAVSSFTEEKLPPLNFHAHYTATGKPKAEDYDATGKAILLRACHDFEAKVIGLNFFPTPMTRARWAEEAFLAACANANCAHSSDKRVIQLINARASRIRGDLVKWTRTKIQTVFGFNADKGKKYNKKIYQGLSARNFSAFLYKDPDLLTGYAENPSITTFISYIFSTRIGRLYESYFNPVSLNMLSGFFAVIRFAIAEWSTGECIQNPPKFTEVDNNPIMMRYLEDLEKWAGMNKNFTDKFRSRMYSRALSKVYKTQESTHSSHITGSIEASMRLELELRTGDTESEDNGMDEDSDHSDYSNPAPVDLSSAGAPRNPSTASSSTEASGNSPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGA2</accession>
    <name>A0ABQ8VGA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="844"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="946"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="773"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1140"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1178"/>
            <end position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1394" mass="159491" checksum="CEFB6CE4B5C65873" modified="2025-10-08" version="1">MSSIHPSAEVNPPSRKRRRSSPTAEAPYSTKIRLVALQRDDSNIKMITVENSVKTLETAIERLLMPNVQEHPEFEVHIAELCSFKDKYQAKFRTQSNDNVDDLAEAEKEALYIAQVKSSMTEKSLIGTISATNIELNKQRANVTYHAHQLERVKNIVTKDFHLKKDLSQKIKDLERQQQEENKASKNEIRLHKQKMMDLITVSEGLERQIALFKKNNQNQASTIKEAAEWKNQAKRTVQLLESEKAELNELLKLKESALQSANRNFGNLKLKTKQLEISAANAEQFGNAKVQELQVALGKNDELESYITVVKQEFSRDVEGLRLSLTDAQSSHEVTMEELQSCKQRNEELQSAIDEIQYKKNEQAQELDSLRRENIDLLDHRNREYQELRQNYANLESTIENLKFAGMETSKNEKETEDCKRKQLVTENVCNRERDWEMFCKQNERIMESSHVIIMAKDHELECRTSELNTYKAALIDMEINAGRTLESLQHHNQELQSLVVVQDAKAQQVDTLTDQIEKKALELENLRTEKINLAHSLSLKCQEVENLRIEFRSSMQTIKDNDAELEKINLQLSILNKDHQDACVLVEEKDQIMKNMRDTLVDKEKDLFRLYKEQEELKCTLDAARQELGNLQYFPSKDAEEVARKSEALEREDRYLQTETGQIKVTNDAQTQTVHENDDPKAKSNNSWTTEEGVDLLCATLHTQLSFADEMTENRAVLSEERVLVCPLIPEPLAHQKLQKQGKETMSAIALLTNAHTTENHESQVQSNADLSEKGKTEKPRATHVDAAMESDKEGTRLRAIRKVHKLVEAGVAYKAAEDTVKEHARGSGSSNVVVVDLCTELAMAHAENVDLKTKLQAVEEDCKGKEKELQSMQEKVLTSDESLKNMIEGCKSLEIDKNKMKILFAEKHTQLLNEQDQTSQLTVQLKDLHDSHQCTLHIKELELEGLRVANKAQYQELEHLKDDMAKNARDLAKEQAQQLQAPQLKESTQDVDTVIAHAETVNLQKQIRIFEKERGSQEKYLKSVRNRLLSSDESLKRMTEDRKSLEVVIKNMKAHVAEKDAQLTNEQAQTSRALETMEQRLEDLRTTNQAQYMESGSYKNVKTNAEDIVAQNDQPMNAQVESTDLAMQSESLHKQTDPQQSQPESTLENPRITNQAQLRKLRSSKDKEIDAQSIKEGTSPLTNAQKLHANDTIQDRLNKERKYTMARVEVEALRAELNDLHTGQQKRVSKSQEHRQQADYYRIVFERMNQDNNSLEVRRIAEEKKLNAALNSNQALENQVLQLQARLRPRFQEDGLRFRISEQSLNTLASNPADCIGAESPLNPAIQSDSNVPKTLDVESWRGLKKSLSNADVGMEVATRHKYALSLRRKARTSVYLIAVSNQLCVDLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH46</accession>
    <name>A0ABQ8VH46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="290" mass="31911" checksum="791CD3EC555705B3" modified="2025-10-08" version="1">MNHSVSAEPAISSNELEFSSQELFELDADPLANNTEDDPNIEQLTDTGRITSGLIKDVHAKLGSKLDKWKVPSTISNKFKNQCKAKQMEGLEPQPCEDSSDDKDNVPSVRPRAKKARMSQKIAADKENDDEYELTAYIVVQNKDVAAGSSHRKKAVVENSSTMSGPISILSSHTYNDFLCAIGACVKCPVHHLVLHSMSYCPQTPKTSVPLPVGTKDAFQAMQSFFRSCSHSSVSGALNVFITMEKPIKPLDKTVDWEMDEKVFDSDNAFTSTFVTAQKVFCKVSVRGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH96</accession>
    <name>A0ABQ8VH96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="335" mass="36803" checksum="1EB6D154ABE978F6" modified="2025-10-08" version="1">MAFSSTLIIVIIIIAVVILLASLLVSYILWSKSKRKVPLPPVQPLAHDRERSFHALAAEKERERSMFLQIQIAPSWSELGTLKSAVSSESSCTANTATYPVPPGISSRNRHAPPRPLSLASSVHTSRSNLSRAIPHAPNSNVQIVLPVPLGSSTVDYSRNSVADGWASHVVNDSTRSRSRPRAQSLSKSHSRSSSNRSYDYSRPNPSPPDMSARHRARTNSLPYSTTSSNQVLSVPPMPSQYPSSMGLILPPPVPPPVPRIPSVYGQLKSTATVSTSSDPDLDGAEFPPRRRSRSRGPTHNQSFHNSDWVQEDLASQVDRRTGRPRERSRNRGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHB2</accession>
    <name>A0ABQ8VHB2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_393882</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="82"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="806"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="817"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4489261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="833" mass="93898" checksum="81420BD3D97638A2" modified="2025-10-08" version="1">MDSPNQITIATPMFENAKEFMIENSVFNSVGRDLIFNISHTDQFRGLHRLYKSASTSAMYNSETQYPPARCHEGTREAVLSRLSQWIADPKQESQICWLYGSAGVGKSSVAQTVAAQFAHEGKLAATFFFWRDDPTRNSVRCLISTLVLQLANAIPRLRTAINAVVESNIMILDAPLEDQFRELILQPFQSLDDSEESSPLLVILDGLDECIDGRSQERVLLSIARGLVSGGIPLVFLVTSRPEPRIKNVFETLAHICIRIALEDSDEDIRKYLSDGFAQIYSRRSTTMYQVHQPWPTPKQLDELVYKASGQFIFASTVLQFVDDDYSLPSERLRIALGLTDREGVHNIVGVPFFEELECASSDRPFGELDRLYQGILSANPNPEQLVRIIGSIVVFHDIMTPTTKMLEELLALQPGAVSATLSGMHSLLKTTPDSTHVAPHLFPIEFAHKSFSDFLLDSNRAGRFFIDRPAHHNYLTRRCLKLMREKSLSPSFAGRMQAWGLRPLVRLKPFTYALGQELVYHCNWAYHCISAITTPELMFELRATDIYAYANRLLMLGPDLYQTAWKSIAQVGVFIGEVNRVKRWAEINQNPPKDLIQRFQNFSLGFYVSAVGTCHDRNRQLATLGNLLAFNAVIPDIDLGFDLYTSEKVFCQIIGCDESQLADLRHICPLRISAESKSSPQSITNYSNGFSSPGTQSTHTVFVDLANCHATLAARCIERLIHDNDSFLYAERYWCKHLTRACPRHDLMVSLEECIRNGRLDNDPESVNEVFKWLKELPSEGHSSTSRILMTTLGNILHPASLEIKESQSKSSSDSDAESSEDVFFDCDEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHK5</accession>
    <name>A0ABQ8VHK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_764700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="211" mass="24437" checksum="025E5E3E71823975" modified="2025-10-08" version="1" fragment="single">ILNCPDPCHQLNLMMKDVMPMRIVSAITTYFSHSNYGKYQLRDELKNELSRRGIQVGGATRFSTFATHIQSIIRCSDAMERCVSKDHIKFDTPATKELQKYIIHGSDHFKFQLQLHNANLLLQPIAHGLLTLEGQNTMCSDVFFVFIGIVIGFTRVFQDPSNDVYCHRAETFAVFDRRFDIFLNDCTKDMFILAYLLDPSAYFYLWRTSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHT1</accession>
    <name>A0ABQ8VHT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="20349" checksum="B2BA7EFEFD77F710" modified="2025-10-08" version="1">MTSNGGRNPNAGFNGAPPKYLNDFSKALAGEVRILLEEVGKLRDERRQLQFEIAELMAVKSKHSLGGQYAPPEWIAKQLEPPPPAPPPEEAPPPAPSQPAPPGWRTVHKRPERRPKSTKAIEPQVPQAPVLPAPHPHMATGSSVPAWAQWRPNPILSPAPRQGTPAPFPGAAAPAPSSRGGLFGPPSPPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ93</accession>
    <name>A0ABQ8VJ93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_761907</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF319">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="265"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="453" mass="49433" checksum="3D8A2060894F63E9" modified="2025-10-08" version="1">MASRDYFERHERPPYVPTPDSLSYDEGAFKDIEKSLPIEKCTAIPTLQESTPIDDTPDGGLHAWLVLFGAMCIAFTTSGYMSAWGVFQAYYEHSILQDSSPSTIAWIGSIQQSFLYIPTLIFSRLLDMGYFRTMLTSASVVFIVATFLIAQCHVYWQFLLCQGLLTGIAAGVFSGPVIAILSQWFRKRRGLALGLYAAGASLGGTVLPITAKALIPTIGFPWTIRVIALIIMFGLALGNLTIKQRRSSSLVKGSLFDFSPMRSHAFLVYCFAAFFVYLGYYSFTTYVAALAINIGVSTSFSFYLVSICNACSGVSRITSGLTADRTGAMNLMIPFITLSVVVYCVWPFARAEVSLVIISVLYGVSIGPFASLFSSPVLDLGEKDQLGRRIGILMSMVGIAMLVGAPITGAVDKSRGPIAMGLYAGTMMLFGAILMMIVRHMKVKSKPSYWSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJG7</accession>
    <name>A0ABQ8VJG7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="50033" checksum="79586869DFBD5DF1" modified="2025-10-08" version="1">MSGSHTQTTTATSLSTAGPLGPHRMIPPPTQSIEPEEEEDLEEDEEEILRRAQEKVRKVKEWKAAIMAKKRAEEEAAQRAEEAAWKKKESEARELEERRRRLAGVATACSRRGSSPGESSVSPRRPVGEIKKGKGEAKAQSSGPDTSQLSYISSLSVSFISVSPQLYFSSLFPISGLFLSILALSTPLLRLTIYVEALQFVFHPLEPPIRFPIPLHCSLSSPQLPTCIGYTSPPHRSGGYVLHSTPLGLSIRSTQAPQLPLVRLPSPVLALSHTSLYGLGGYCVRLGPVWPVGGDPDNGGDDDEGERAPCERCRSKKIPCQMQAGKRSSIICKLCHDAKVKCSYSGWPSTVKREGGGQPTGEEGQLKANNYNRHFNRKLDWLMMDAARRRNSPPEMPEPGPSRLPKKRRRVVDSEEEEEDRRVGEGDEEVEEEEGEEPAPKKARSEKGKERAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK52</accession>
    <name>A0ABQ8VK52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_271158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="347"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="480" mass="54018" checksum="49D08FED4AAB9A31" modified="2025-10-08" version="1">MTSPADSAFASTYIHSFDRERCSSRSMKTKRCHYYNSLGQPRTLQRNGKPFDSNSDYGCKCRRFFAHPEDPEWASLPPVPAPPFLVGTPSPSPPRASSSIGYHPMPVKQDNAKSLLTLIELKSDYESLLTQYRRLQQILNNTALLPSSHPSGQQLSRAQLVSRRETVEKNMKEAYARLQEFDQNTPFEFGNLDTTLEPNISILKNLLRELKFKLVEAESLKNTVESNFKKASVEQAQVESDGDIIMNAPSSTFLKQDGYSTPPRVSLSTEKHLVLLQGMLDRISKQVASVESNVMEQEEVIKSVIQSSHELVTSSESVVGGIHQDIEHFDDELSELAAMTAETIAEDNRLDIEYQKLQKEREDQEIELQKLMGCLEKLEKEREKDESDLASLSTALTAYMEKPTVSPLSSPFIPEDIVVALEEQITPLIRNAIKPHIENLRSELEQEITKHEMETSSTLSPVFTVTHQALQSASNAMSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKA5</accession>
    <name>A0ABQ8VKA5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_825009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="2">
        <location>
            <begin position="194"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="456" mass="52325" checksum="FCB7B431D66D23BB" modified="2025-10-08" version="1">MNGWIQSLSLRASKQLSAFRLVTGALIAVTAYLCRVRLLRWRRHTAIHREFGRKYESGLLTPEDAQKIIHTSALYDMPALMNYALAFALFKTYAIPTISKILSDTKELKSAASISKRYADTEILISTWVFCPITGKSTTVEQPSTRSRQSSATTEPKKDQIGGTTELGNLQVDDPRAMIALARVNWLHSKYFITNDDYLYTLALFVFEPPKWARLYGWRALSPMEEEAFYIFWVEIGQRMGIRDIPETIKEFKHWVVEYESRTMIPAQTNHDVATYTTEELLHAVPEFFGLKHFCRRLTICALEKNVRIAMMQPEQPSYLHKIFRMTLHTIGFIQGYLCLPRSDSDPGAVFDISLSKATANAVSVPSSKLHRMHPKWFRAVPWYMPEPHTFFGAFRNWVAVKMGFYDTLAGPMLKSEGYRLEEMGPVKFDKCGNEEVIRMAEEFYGCPISGPFSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKP6</accession>
    <name>A0ABQ8VKP6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="448" mass="51614" checksum="B2F8D5FA111D9F3A" modified="2025-10-08" version="1">MKGTLSDPDQRGRTWLQLDNVCKVQLSATETRKYKEWRESNARSSQNTTSTRQSSFEDPTDSFFKTLNVSSPTSIDSSATSVPLAQRKVSRKIRQARIQLYEDQYVLDRAPARLRVGQLDVSDSFGWRWYQCSQDVQVLLPPDASVQYTTFLLLEEAQFKCATSCKTVEKFNKARSKFNELCSQLKSRHPVRGIMSTARRYALPVGFRCPSIDRLVGRPQDDCERLTPEEVPNTTELLSQPDTYWRRWLYIGSDIRILLTADVAGQLAFLRRNGVSHATHPLMRQIFADFQCLSSEIITEQLLRCPKTREKLHVLSPDSRSQTLDEAVAHIEVNICRSTRKQIKHTTLKPQWHAVVCELGEHVDFPPSSRGNHPRDEQDVLAQPKWSPGVVRRVARRRRGVRNLRAPNTDKELPPLPPETLDEQYVMDIRTSNDSQKEKLWIRRKILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL00</accession>
    <name>A0ABQ8VL00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent rRNA helicase RRP3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP-dependent rRNA helicase rrp3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_828124</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17954">
        <property type="entry name" value="DEADc_DDX47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044765">
        <property type="entry name" value="DDX47/Rrp3_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 13 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="40"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="239"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="398"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4495474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="442" mass="49287" checksum="3FFE1D3ABE8B59E4" modified="2025-10-08" version="1">MINQQHQVSTFSELGLSEPLLKTLEQLNFTTPTPIQIECIPPGIEGRDIIGIAPTGSGKTAAFVLPILNHLWDNPQGMFACVLAPTRELAFQIASQIDALGSAMGARTAVIVGGDEDRVKQAVMLARKPHIVVATPGRLLDHLKVTKGFNLRNIKFLILDEADRLLDSDFGVSVDEILKVIPTERTTYLFSATLTDKVAKLQRANLRNPVKVQVSTKYETVDSLLQYYLLCPLVKKEATLVSLLNSMAQNSIIIFVRTKEHCQRLAVISRILGFRSVPLHGDMSQSQRLGALNQFKSEGSNILIATDIASRGLDIPSVDVVINFDCPTHSKDYIHRVGRTARAGRSGKSILMASQYDIEFVQRLEKVLDKKLDLYPHDPEEAHLLRERVDEAGRVAANQLREDKRAKGDARRRRKPLSSGDRDGEEDLDEVNRFVMKKKRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL03</accession>
    <name>A0ABQ8VL03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046693232" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40348" checksum="87876CAF758F915E" modified="2025-10-08" version="1">MFIPHLPRMRALALLFALPVIRAVPALRPVGDNVCGQLERLHLITSFENTAQEIIWTRSLVHSAPNLRHLYFDSSMVPLPIVRGQEWCLCLRTINLDAAYGIPPEDFFLLLRNSPELVRCVIVMNLDESLNHLTRWEEMPKVVHSALEELSLSCEDIFLGNVLDLLTLPALVSLKLSTVGDEAWPHTELMHFLSRSLCILRELKLDSEMMTDDQLLIYLGTVNRSLRALYLPTWKSTSERIFRFITPPKLIGTVSNSPDPSSLPLDRVLPFLETLSFGITPHLHPASLRDFIECRLIDKCTTTRLRAVHIHLLLPLIPGLATDLDLSLKALLDQLADDKSITLKITSNHLQFPSVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLQ6</accession>
    <name>A0ABQ8VLQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_894694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="746" mass="84811" checksum="1305B6ECFCEAA21E" modified="2025-10-08" version="1">MIQILRIVLSNDTEARFPNLFAQRRQHVNEDPDSPYFPWADRETCVLDILHHIPRCAFSRKQNVERGYAVHTSLIRAIHWAMLTSGVPDLPSDCTMDDIDKEMQRMCGIRSIRFEGKLGHVYYANDLPAIIAQEMSNLNCGPRLSEANQVECWLKEMDPDLLTPAHQVAGQEFFTLEPTVLQNGNVCMPSCWFVRNKKVFAKAWPMRVVDIEDYGHGWAVQTFSEIKISDSDLLLSYQQFRESHLSLGLMDPSLIVAEEESSKEFVIWEKTELGKGNRWRSKSNGKRVLAFPIWLYCDDTSGNVSKKWNKHNSFLFTAAGLPRHLANKESNIHFLSTSNTAPPLEMLDGIGEQILCMYITTLECTIYDSHLNDMVLLIPSVLALCGDNPMQSEFACHIGFRGRLFCRICLVSGKVDDEDNPSSTADDGNESDASLSSNSGRQSKKRNIESMKDMITRISDFMKRGKPRNREETCTELRSQFIEGARVGGATQYKQMKTESGVKDTYQDEFVAKIQAIATKKGITKAQKEHAITQLKRTFPCHLTSPVGMTPVWRIRGNLTQFFFVGLDPHQDTPVEILHYYWRDAVARTKKDHDLLIGWLSSFNTWGLGISPLLGKTLVNYAGSLTGRDFRAIAQAAPFVLHGLLTDDQLKQPEIHNLKEYLADLEKTIDYFLDCTCRLTPRWFNKPKFHVLLHLPDHIRRFGPAMIFATEGFESFNAIIRARSVHSNRHAPSKDIAHAMARSNCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM23</accession>
    <name>A0ABQ8VM23_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SPX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_218837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14475">
        <property type="entry name" value="SPX_SYG1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPX" evidence="2">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="260" mass="29823" checksum="35A9115F396590E9" modified="2025-10-08" version="1">MGLGELPVRRKSFSTKKTASQTSLPEAHQSAHHRSSSNQLSRTISGTKKPKSQKSKGLLAQANTTLRSPPHPFSGSIPLHDLLPLLSPQETSFIDALDKELEKIEDFYDARKKEMETRSKLLEAQLIELNVHQQRFNEAQAGSSRWNIMLRYLTRYKAPEPDILDHRSSKKTHEIEGNLPHIDSGHMPSSKRDSLHHHLDPEEYQTAKKKLNKAVFEHYRGLEMLQNYRILNITGFRKALKKFEKVTRVKNRSLAVYDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMM1</accession>
    <name>A0ABQ8VMM1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_821892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38487" checksum="8BA8B17F728DF2F6" modified="2025-10-08" version="1">MADHPKLAPRSTEDIENQMLVDKAECKISVNVVDFYHNNRMVVIETQEINETGKVIYSRFKLHLSLLELHAPVLANFLTQALESVEGTEENPVILPFTTREFTCFLDWIHDREWRPFKIMEESLVDLLRVSSTLKADDGISYAVSGLESLRLPSARMLQLVGDFHHLPEVHCWVGPAVKDLIQRPLGEITNSEAQQIAAAYPTIARTRENIQRLLTQVSQRSFALKLADKDQQEEADLCLTHKECQKAWKSVWRENIGYLLLDFQKPLTYRELLELLQNTDFPKVNPSCKARMLNWLSRKTDYPGMKELVEEAVASIEDIYHVPRRGPAPENPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMY1</accession>
    <name>A0ABQ8VMY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PLP-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_758840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="41"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="173"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="450" mass="51263" checksum="A4A7D7687EEED111" modified="2025-10-08" version="1">MANVVRLQYESKPPPFGHEMRKCFSFDPEYINMNHGSYGSLPSPVAEAIKPYYALAEANPDLFHRFTSIDLIRDVRKRMAKFVGAAHTEEVVFVPNASHGLNTILRSFIWEEGDIISSCNTTYNSISRTAEYISDIPPHPEAVQFTLLFPTSHSEIIQNWRAYVKSLNEIRNQSAQKLGRRPKIVAIIDSIISVPGALLPWKEMVKICKEEDVWSVVDGAHSIGQELDLNLAEANPDFWVTNCHKWMYAKRGCALLYVPKRNQHIIKASFPTSHAYKKGGGSNFVEQFEWNGTIDFVPYISASCALDFRAWLGGEHVINDYCHRIALEGGKRLAQILGTEIIDQGQDFQFTLSMVNVAVPFPPTMSSAFEIDMAFRRKLLIKRKIYPAFFYHNGKWWIRCSAQIWSQVEDFEVLGEAILEASKEILEEFGDGTEKKTMIIEDKDERLIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNC9</accession>
    <name>A0ABQ8VNC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_171615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="897"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="954"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1147"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="973"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="989"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1265" mass="141219" checksum="12ADC2750A1AB9A0" modified="2025-10-08" version="1">MRDEDDMERRIRVYKRRQAKAAGNSQEPSGDTAEEEEEQPNHLPTRKRKVIPVTEGRTQVKRLKKEEVPPSLLANNGFVRVSQLVRRRPAVTGDKGEGPSRIAGPSATQPKPQPIINKPKTPTIPQKPKASPRPQKKVAPEEQIMIYPNLPASNNYSGQQFEPKVNLRTPTIPQKPHASPRLSQQKVVLEEQIMIYPDLPALDDYSGQLFEGGSDAEMQLDPEAGQEDDNDDMEVNYILADPVEPDSDKTNATNSYLTPRSKKQPTAGTSSSDRNRVPRGSSDGMTTTADSGFFESTTPPPPFPRHTTNPSNNIFDGSSDTDSPPRPLKARPVPKLIEGPFGGARHKHPVRRIVFSSPESDSIKTPAKGAWPPVRGTKRKLPISPEGNITASLSSSKSRHVPSSSRPSGSSKFSPPLPSTRSPLIQSSQKGEEHQLVAEDENQPSGSNPRVSEQSARQDDELQEEEVEEEKEPLFTQRIPSRDTDSHEEEAEPLFTQRIPFREADNHEEEEEEEPLFTQRIPFREADSHEEEEEEEPLFTQRIPLREADSHEVEEEEEPLFTQRITSREADSHEVEEEEEPLFTQRITSREADSHEVEEEEEPLFTQRIPSREADSHEEEEDEFEEEREEKNLEIDDTDIAIPQNQELSHTDDEEPLFTQIPPKSPSCEVTAEPAFFAPPPRASHASHHPPRSSHASHIYPILHPFDILEPQYHTPNRLLPTIHPFDMPDTQHSQPQPSVPIAIGTPRSDCSDDITRPSVSNETAESVVRALNAFILEMDRSRKTIERDRLTRAERARKEAERMATPDLTSSEQSEQSLNGAGVAVSEISREKVKERVVRARGSPVPMGAKRKQVDRRRSGSVVLPHDHPFLHGGTPDAHLPDSGYLRAIRTEVGQGVVQKQERSLYKDRSSKQNLDDLAANEFPVQSARTPAQSEPTSSGSGIKLAIRDAVSHSSPFRNPGQSTSRNKGKNRVIEEREVNSSNHRDFTPSTVSTVRSKQIDLRQLERAQSRRRSSLPTTGRNTSGPVSGFSASSPAAPAISITPTTGRPFLSASFSNPRRVAHTPPDPPHSPLKLSSSDQSRLIDQTIQNMAEEYQFPPDYVRRVWKEAGDLNEAVAILRQLRDMAGTLLRKASVRRSSGFFGAASDNERSRGVSPESIPATNINTFPRDRFRSPNRSDHPDSRSRIDGITRKRMTSSSGNRREVFLPKMLDGPLPEVGYSPPTHSRAGQIALLSQQGRVKEAIERDQRRATGRGGVLVVHPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ69</accession>
    <name>A0ABQ8VQ69_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclohexanone monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_864716</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="545" mass="62321" checksum="700A1830BE09AFE0" modified="2025-10-08" version="1">MSETHDYDVLIVGAGFAGVHQLLNIRKLGLTVKVLETGEDLAGTWLWNRYPGAEFFVHVLCARVDSPSPFYQFSDPELWRDWTYTKKYPDWREIQAYFQYVNDKFNVKRDVIFHSRVASAHWNDSVDRWTVTTEDGRVFWAQFLSLCTGIGSKHHIPEFKGIDTFHGDVYHSARWPEMCDFKDKRAGIIGTGATAIQIIQEIAPHVAHLTVFQRTPNLALPMRQQNISAEAEEKLKKDLYPVFFRRRDQTFSGYDYDIDPKSILDTTREERVLAFEEKWEKGGFHFWVGSYADLFMNQEANDEAYAFWREKVRERIPDPELQEKLAPMQAPHPWGVRRPSLEQRYFEVYSQPNVTLVDVNKTAIEEIVPNGLKTSDGTVHELDILVFATGFDMITGGITSIDIRGQDGLSIKEKWANGVKSYLGLASATYPNMFWIYGPQSPSGLSNGPSSIEMTSEWIINCIKYMKENKFLSIVPTEEAQLAYSEHVDQLGAAALWSKAKNSWYMGSNIEGKKVQMLQFPGGLPAYAELCNDSATKSYDGFQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQF5</accession>
    <name>A0ABQ8VQF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_756694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="75"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="586"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="654"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="684" mass="76345" checksum="D9FC717C53B918A0" modified="2025-10-08" version="1" fragment="single">MGSRNSTYASSSDTVTDHSGTWKNFLISEVLTIYLSLLADYQNREIGEWLSPFDFIEIQRVILHSRAPNTGLKPLLSEAYVRWRNGDDRTLLMSGLPGAGKSMSAASVVQDLNEYYEGCKVAVVCVFCDFGQMQMQTTDALIASMLRQLIQAHDTVHSSVTSMYMHHTSRSTFPRSDEIVAAFSTSVQQFESVFVVVDALDECPDDQTRSQLVSTLNSFPVSLLFTSRPHPSIDQLLGGCTRQDIIADKHDLWIYCEERFTLSRVGRLCSPDSKQEILNQVVQKAEGMFVVARLLMDALLEAPNVKEALGIILTLPTGLQGTYGKTVQHMCEGSNPEIKDLALYSDLLTKQSLVDACAGLITIEDRTDKVRLIHYTVHEYLVKEQVNLWTNVQRTMAVTCVSYLRYNLPRLQYDPEVYIEEEIRNASIQHPFFGYALFEWGHHVHSCGELKLVNELLALLASDTHCTLSRMLTFNAMNSPKWTSWSALHFSAHFDLASTFLLLLHYHDNVRLNAEDHSRRSALSHVAQCGYSDVVKILLQDDGIDVNQRDGKGMVPLLYASMEGHALVTGILCERKDISINASNDDGRCSLSLAAQRGYDRVVKNLLASPGIDVNLSDSNFRTALSFGAQHGRTEIVRALLSRKEVAVNRRDILGRSPLSYAADQTTKGEEVVSLLLDAGADED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQJ5</accession>
    <name>A0ABQ8VQJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U2 snRNP-associated SURP motif-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_163489</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="183"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="5">
        <location>
            <begin position="348"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="CID" evidence="6">
        <location>
            <begin position="431"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="286"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="604"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="641"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="706" mass="77977" checksum="3D52B4B6BEF0D566" modified="2025-10-08" version="1">MDRKAKPGPSKLSAFFDDDDEEPPSFPHKVAVDDAKLSQYAAGTHRKSRREKEQEAAEAKKREEEVNAAKAYADFIDAFEGGDVGRKSGSQFVKAESGSKYTPALKGLSDEKSTKFELDSLPAHNAPKPKGKRAMDAFLEEIKKDQADREAKYSRNSQGRSVTALAAYEGQSGSKDRGDPQTSNVFVANLPPNVSEQSLGSFFARAGPVGSVKIMWPRGDGTIGPGADMTASRRSKNSGLSGFVSFMTRRDAEEALREFDGLDWGGSILRVGWSKAVPVAAKPMYVSNESRTRNHSRSRSRSRSPGRGYRRSHERSRSNSPRSRGHSPRRNHQILSPTFEEEAVTDVFIRAVAVEVKGHGRSYEENLLKREATNGKYAFLRKDGRRYNFYKNLVEDERSMSPEFDDEGYNSVYSTDSAEESERERVRKTTLGRLARKRFEAMLRALSGKRGEIARCMAFSLEHAEAAHEIADIIVASLLVEGTPVPRKVARLHLICDILHNSAASVPSAWKFRQEFQSRLGIVFDHLSNIYHSFPGRITAETFKKQITTVVDIWEDWIVFPPAFTSELRVRLEGMAMENKTETAETAAMEEVKGDTAKLPSRFTTSTFKTATEPASAVGVDEDLDGAPLDTATEGRVDGTSMDDVDGTPIEDTDGTPMEDLDGAPMEDLDGTPMEDVDGIPMEDVDGAPMDNMSPSLEDLDGEPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQS4</accession>
    <name>A0ABQ8VQS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CP-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_817368</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="4">
        <location>
            <begin position="100"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="445"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="603" mass="65928" checksum="77DC420ED1C96AE1" modified="2025-10-08" version="1">MTMGRTKHRKPIVPSKSKLKKDPGIPKLPDIKQRNELRQRARPSIPTHRSDPDCVMASEPTLSSLAQLASNAEDAFDFSQNQDPSSSTGKTKEQIRKHYLRTLHKVIDQSDIIILVLDARDPEGCRSRLVEEEVRRRETEGKKLVFVLNKVDLIPRANAQAWLKHLRHNTPTLPFLSPSSAQHQRTNISSSTAPSLLKLLKAYKPKAGSVIVGVVGYPNVGKSSLINSLKRNKVCAVAAQPGHTKELQSVQLERGMRIVDSPGVVFDEDDEDFKGQKKGSVLLRNVVKVEDLDDPIAVVEEILIRTEKETMRKIYSLPDYNATLEFLTMLALSSGRLLKGGTPDITSAARQVITDWNHQKIPYCSVPPTIHPSSIPSTIPSSMISAAPSLSTAPDLSGSAQGQARQVIAPGAENVGHAQILSSFSEPFELEGLFGAADAGAFGGGRSGPDVNMDAEGDGDDMFWDANETLGNENADDGMQEGDATISASEFASRRTSLGKHLRSPSPSISAGPSQPHEHSNVQLRQAKRHRKSHLIPSYDAPPDAHVLREMGKSNPLNRRMNRIMAKKERKKERKLSRHVIAEGTAGGMEVDDSANLGLTFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQS7</accession>
    <name>A0ABQ8VQS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_124448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35336" checksum="AC89C4CCE9BDCA54" modified="2025-10-08" version="1">MRSSDIRRNDSKSSTHPLNSPRRKSRMPSLFNSLRGGIYVAAILFTVICLAMAGHFEAVLASSDLTRFVPFALFVGSASLLIILLLLGFSFLFRERNPISTRLELASLALAGIFWLALGIYLASSDSQSADVECFASATSTQVLDDSSASFHTEQYQAMYRVLNAFSLINATLLLIFAFGLFLLALRRHRKGDEHMWYGPVTSCAWFNEYSKRRDRVKRSQSGILPVETVVPVFTEKPSRRSTRHRSQSRGHSRGHSQSHRHRREPTTYPARVYQSQMNSKYVPKEEPQSSGSSLLASTTESFDNGTMKNPNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQT8</accession>
    <name>A0ABQ8VQT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_817597</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19690">
        <property type="entry name" value="bHLHzip_spESC1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040106">
        <property type="entry name" value="Esc1_bHLHzip"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328:SF15">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328">
        <property type="entry name" value="PROTEIN MAX MYC-ASSOCIATED FACTOR X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="5">
        <location>
            <begin position="365"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="251"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="466"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="466"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="526" mass="56816" checksum="EF5848DBAE0AF90D" modified="2025-10-08" version="1">MVGPEGDRTSTTKSAIRSPLMRPAIKSPSMPLAPLEYLQQNQRRGSITDPSLHAAPLPPVNPQISRQVASNSSGPRSPGSIGPSSTYVFGDATATTSDNSALRKILRSPSMETEKSRATEGVVTTEEGRRQSTAGTELQMAGVKRKMSVDKDVPGETLLAGPGVSGIEVEMEAPPPKRRGSAIDTSRIASLSLNEQRRNSVDSRGSHWAWTNDRRDSTSSIFSAASGYSQAYPGTESPQGRHATGITTFAWPVSASPHPSESINMQHEGDPNVTASAPLHMMPPMNFSQDRRMSVPNVLSASPPTSTGPTRVLRSRSRPPSRQTRAEDAQSASPEDPLADPLASSSSSVKAAKDSGATPYSRSPELRVSHKLAERKRRKEMKDLFDELRDQLPADRGMKASKWEILSKAIDFVNQLKQSHQDMAREIDMLRHELDAVRQNAGLPPFTGPPPPHLIYAQGPIPAPYPLPPGVLPHPPPISHPTAQRQHPQLPLSRPASSQNMLPLGEQNPPPPLNGDLPRPEVHPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRV4</accession>
    <name>A0ABQ8VRV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Proteasome assembly chaperone 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_757962</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the PSMG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="entry name" value="PAC-like subunit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016562">
        <property type="entry name" value="Proteasome_assmbl_chp_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12970">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12970:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010044">
        <property type="entry name" value="UCP010044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159659">
        <property type="entry name" value="Cgl1923-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00019186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="236" mass="25784" checksum="FC79712F43CB20AA" modified="2025-10-08" version="1" fragment="single">PVVSTANVAQLSVDLLIFSLGLVRIAVLDSKYFIPLVGSRENGELGITTPFELYGKGELGIVVLQQRSPILKVMKQEFIDDLFDFVQKSGIAGVLILSGVDLSNRSDEQMLTPTYQLQPNPLHLSSPLHRLNEFPIPKYTSPVPQKPGANNDESQVPFIPGGGITHRMLSSLPKTWSIPLAVLLRFALDGDNRADAHSLASIVAQVMGIDITSIQWKQPESWSGLFGTPHDQSLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS91</accession>
    <name>A0ABQ8VS91_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cytidine deaminase</fullName>
            <ecNumber evidence="4 10">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_55966</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 10"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="11">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="18526" checksum="FBF1260B559B3779" modified="2025-10-08" version="1">MAALSEEQREALINSAFEGKEFSYSPYSKFRVGAALLASDGTIIKGANIENASYGGTICAERTAIVKSAVGSSLMEIVCCPTSDSLRQSEGKRSFAALAVVTDVKSAISPCGLCRQVIREFCAQDMPILLVPADYPQFNKDSGDAEKGVKQTSIGELLPDSFGPEHLELPRGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT81</accession>
    <name>A0ABQ8VT81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_814450</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="58826" checksum="9D82F27AD16BC977" modified="2025-10-08" version="1">MSQAAQPWYEDLQHPHPFIFRTRIRLRARIRCIVPFPELWSNYSAMTTVWSNTKLFDSELAQRLDSLALDQTKWKQMIDHFKETLVVAEEQTLYIIWPSGSARSIQIELDQLSKTKLVPTDKVNVAWALSPDKPYEPFVLFSYSKLVYIFNVHKKVIEGCLRGHGGEITSIAVHPRAAHIFCTTSRDFTSRLYDLTRRPQLKPNNPPWPPSLQPSLAGAAHGLDMSFEEGNGIGRCVLILMGGRSGGHQAEVFGAAFHDSYPIIATCGMDRTIKIWHISYFSDRSEQKLLREDKPLFSSSMIHKARVLSVNWLTSDVLLTHSAPARMLVIANPPVSTEWQGSTQSSDSSSRQYDQDEPGSLTLWKWLSIKRFFPLGWDKAASRQQVLRGFGSDYQESASFRTLSSHFFPSQTSQYITPSLYFSRGSEVPFVVYSYPNTRHLNIVNIKLFEPLLPSTSPPDEGNKSIYPVQNRQIQGWEIALGSMSYTDETLETCIMISGGKMIVAGGSKGSLWFLTVRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTG5</accession>
    <name>A0ABQ8VTG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_876363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="64167" checksum="0874EA679A5167DB" modified="2025-10-08" version="1">MDFSPNDILEKLPELSDDLTHPSQVAIRTFALSLSLSLGPSLVPFVLSFVTGRRSQKTGLAALRKVLRRELGYDSFASAVTLAIGGGAALKRLWESLEAKEDKNSEQKQTESDRCSRSWLLYFDSRLSSCQKTFIANLFTSSISILLLQAGRRRSERLRNIPRPGAIPFPYTYTPSNPSLTPSVRSSPSPTLDLTLLVLVRAIDVAFQSMILKLTTETEAETPESVKGKPTFNKDKFLLTTRLDALVFWACSARIMWCFFYQPERLPSTYVKWIRTLAGVDNRLLRVLRLIRSGEWTYTRGSPTQATLLTTYAKDLSYPSSWGDPLRVPAFGGPSAGRVWELIGVKGRQGLGGIPCELVHGGVGSKMSLAGSCTGNSGIRGVKAFFEAVLVYLPAHFLPVLITRPQVLLRPHRVLSTFLATCRSAAFLSAFISSFWLSVCFTRTLALARLFPNVSHDFWDGPHGCILAGCLMCGSSIWLENGRRRGEMALYVLPRAIRACIPDKIIRSRNRVVTALERLTFVLSLSTLLTAAIHKPESLRGLSRWGLAFIMKGPHAGFWQRRKKNHPSLSRIMIMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTN7</accession>
    <name>A0ABQ8VTN7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_863725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="20175" checksum="AC895DCCB689E969" modified="2025-10-08" version="1">MSGVARHERRMEAYEIRTGFYNKPNGIVNEVAGWKTRRSTERGVKFLCIAENCLGCQADKTVLHVTKLKMRNSRSSATQSEQTQIPDSRYYKAQKLVRLNRQVLNEWHHDEFATLWDFLQNIPAVQQEIRGKNNAGEVEVEDDESYINLITSYLIMEKVFMDLFPKKSPKIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTS1</accession>
    <name>A0ABQ8VTS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="69" mass="7377" checksum="E61907255E67A9CA" modified="2025-10-08" version="1">MTTAVILLVTEIGASIGGSVAIWTRKMPSKLAQSLPDISEKDLTTLFSSIPDMTKYERGTHARTGVILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTW2</accession>
    <name>A0ABQ8VTW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">DNA polymerase</fullName>
            <ecNumber evidence="19">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C8R41DRAFT_893844</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 19">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="19"/>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 19" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="19" id="KW-0235">DNA replication</keyword>
    <keyword evidence="16 19" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 19" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 19" id="KW-0408">Iron</keyword>
    <keyword evidence="15 19" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 19" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 19" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="22">
        <location>
            <begin position="203"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="21">
        <location>
            <begin position="503"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="23">
        <location>
            <begin position="971"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAJ4498915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1069" mass="121186" checksum="7EF7E61D537647A0" modified="2025-10-08" version="1">MSRSRARPDAGNEPAAKKRKIETSFSQRSQTQNQPSFATVLERLKEEKDGKRAAEGGADQWTRPVLHKINEKVDKIVFQQIDVEENTEGNFTALRMFGVTETGHSVLAHIRDFLPYFYIPVPRGFQGEDIESFRDYLNSLTINGAVRKIETVNKRTLWGYRGESKSPFLKLTISDPRTLPKVRDKGECAFRGFFATSIGDSYPTFESNIAYTLRFMIDTQVVGMNWIEVPAGQYELVPPDRRKSHCQIEIKLRWNAFISHAPEGDWSKIAPLRILSFDIECAGKPGRFPTADQDPVIQIANMVTRQGETQPFIRNVFTLNSCSHIVGSQVLSFDDEQQMLEKWRDFVEEVDPDLIIGYNIAGFDFPYLIDRAKELGSQKFPYLGRLKDVQTRVKDTHFSSKAYGQRDSKETPLDGRLQLDVLQFMQREHKLRSYTLNSVCSHFLGEQKEDVHHSVITELQNGTPESRRRLAVYCLKDAYLPQRLLDKLMCFVNYIEMARVTGVPFNYLLARGQSIKVLSQLFRKANDEGYVIPAMKGEGSDDQYEGATVIEPHKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLDKPTIERLELVKDRDYIQTPNNDFFVTTSKRKGLLPTILEDLIAARKRAKADLKKEIDPFKRAVLDGRQLALKISANSVYGFTGATIGKLPCLAISSSVTAYGRQMIERTKQEVEAEYSTANGHSHDAQVIYGDTDSVMVRFGPTDLKTVMALGSQAADFVTAKFIKPIKLEFEKVYYPYLLISKKRYAGLYWTRPEGHDKMDSKGIETVRRDNCRLVSTVIETCLNKMLINRDVKGAEEYVKQTISDLLQNKIDMSQLVITKALAKTEYAGKQAHDELAKRMKKRDAGSAPALGDRVAYVIVKGMKGAAAYENAEDPLYVLDNNIPIDTRYYLDNQLSKPLMRIFEPILGEKASSLLTGEHTRTIQIATPTIGGLMKFAVKTVTCLGCKTALRANNSTNKNGAVCKNCRPRMGELYQKQVSSASELQIRFSRLWTQCQRCQGSLHQDVLCTSKDCPIFYMRKKAQKDVEDANGVLERFDTDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU27</accession>
    <name>A0ABQ8VU27_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation initiation factor eIF4e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_900731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF18">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="281" mass="31520" checksum="640DCCF28B88325D" modified="2025-10-08" version="1">MANSYFSNYSQSRFLANSSQTPSGTQPTPSIQTGPKSRLPSSKHFSTSIIPGSEQSTSKEKTSNGSSPKGSEPHPLRNTWVFWFRQQRAPGNKLISYEEGIKKISAFASVESFWSLWTHLAPPSALQPTTDYLLFHDGIRRPVWEDPVNISGGKWIIRLKKGVADRIWEDLVLAVLGDQFDKCRQVEENGEIAANWEDGSDSGAELPEICGCTISVRQSEDIISLWNRLDGDVKVRERIRDTIRKVLHLSPSTIMEYKSNNDSMQDKSSFRNSAIDRTPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV55</accession>
    <name>A0ABQ8VV55_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mtf2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_899765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="41692" checksum="92F0D4BA70DD9B81" modified="2025-10-08" version="1">MFVAPRRCLFRNEKILRRTLHVSPVASKKKGSKLEIEDLFSDEPGEDLPSSPSSASTPTRVGSPSYLKHRKTTPSKHLDSDSRRARFEELYQRLLAQTSLNPKERRKLPPMRNAVLINLLDLSQNEEELGKVIAQVPKWKDMTRHQPGEGGLEERWGELVVSRAESLSCPKLALEMFSNHAKYQVPLSLPAARHLLHALHIEHPLQDVMTAVALYRVYNLTPIANDLVSLGLVCRALAGSIYQPSHAPKSSPASLQKGNLHASKQVFAALIQSLRGLVSSTDPSLFSVNTHARTRAITPKFTQRRERAKKGLAALEKEKTWLKWCLKRIESNLREVEGFEKVAWLRQWREAAGHIRHNHDSHSLTATALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV63</accession>
    <name>A0ABQ8VV63_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">N-alpha-acetyltransferase 60</fullName>
            <ecNumber evidence="7">2.3.1.259</ecNumber>
            <ecNumber evidence="1">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_810789</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-methionyl-[transmembrane protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50604"/>
            <dbReference type="Rhea" id="RHEA-COMP:12745"/>
            <dbReference type="Rhea" id="RHEA-COMP:12746"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="ChEBI" id="CHEBI:133414"/>
            <dbReference type="EC" id="2.3.1.259"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the acetyltransferase family. NAA60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.259" evidence="7"/>
    <dbReference type="EC" id="2.3.1.48" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045141">
        <property type="entry name" value="NAA60-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14744">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14744:SF15">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="11">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="189" mass="20756" checksum="5D0EB03B3F4472E9" modified="2025-10-08" version="1">MSDFTIRPLASADIEQIKKLHATLVPVNYPPSFFLHLLIQNSYSCLIALEPSSGEPVAWVSASLHKSSNLIGSLEPHIQLLTLGVLPEYQHRGLAKRLVWEVIASLHKDPSTPVPTVYTHVCTSNTPAQAFYESIGMKFLPAPKSPSGKPYVAKNVYTYPPLWAQKSAVGNNELFESKDAYVLVGKITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVT8</accession>
    <name>A0ABQ8VVT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_914994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045396583" evidence="2">
        <location>
            <begin position="22"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="32008" checksum="64B501206BC3B270" modified="2025-10-08" version="1">MVQIYTVLGALLAAEAASILALPVSVSEVGIVTDVPSLLQPSFVKSQERQLEQNRGVDGQPDNPKKRRTLANEAPINSVDEGKLLGTISPAVIEPLEKRLIELSKEPTKDASYKQLLKSLISNLQSSQLLKDRLTSFSQSRNPPTLVQHALAILITQLRLAFQKQKPNSSDHILHEISKLSDFYQMKILSKWAGSSNDVNKQDVSKQDEELNAHIDEMVEAKDATSKYWAQVNFNKWFQAWLDLSQGERGISGGNAKGGTSEKAKRSSALKDIPVDQHRRRQLYGDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW35</accession>
    <name>A0ABQ8VW35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051035">
        <property type="entry name" value="Mito_inheritance_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36091:SF2">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="467" mass="54033" checksum="29A22FED719271D7" modified="2025-10-08" version="1">MHDGFEMVARIPYTVTVPKFYAIASEVATMRFLRSSGLPIPEVYDYSPSSDNAAKTEYIFMEFIRGTNFSDVWLDLEEGEINSVLRQLVQLESRMMSIHFPAGGSLYYTEDLEKMTGRKGILLNDERFCVGVDARVRMWYGRRSQLDVDRGPYESAEAALEAVARKEIAYLRQFGQPLLPFQRERREYYEYKEQLPSEHIKNLERYLLMAPLLIPKDPALHRFCIRHPDLQPSNIIVSRSPESNQLKVVCLLDWQHASILPPFLLAGIPDRFQNYNDPISEALMPPSLPVNLEILNESEQNRERALYHSRLFHLHYVKNTKEYNRRHLDLIIDPISMFLCRLFDGAGAPWEGETHTLKTALIEATEVWARLVGQGEAVPCPVVFDPEDLRQTKELSEKLQAVDEAFEEFQAMIGLGPETWVTNEHFETAVALGELVKQKVLARIPEEDRARTEAHWFLDDMDEKDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXZ8</accession>
    <name>A0ABQ8VXZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">endo-polygalacturonase</fullName>
            <ecNumber evidence="2">3.2.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_913182</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045552469" description="endo-polygalacturonase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4501189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="360" mass="36832" checksum="D6284079D2903B83" modified="2025-10-08" version="1">MQSLLAFTILATVFSGALASPTKVDTAKRATCTVDSVSTAEDLTDCTSVVITAFEVPAGDTVTIKAASGASIEMTGSVEFAFTSTSGPLWTFDTTDATFTGNGFSFKGNGELYWDGEGTSGGTTKPHPLIKFEGSGSFTDLIIKDSPAHAISVGTTGTSSFTNILVDNLDGASLGANTDGFDVSASDVTFSGNTVYNQDDCVAINSGTNIVFENNFCSGGHGISIGSIATGKTVSGVTISGNTVTESMYGMRIKVDSDATDASVSDVTYSGNTISANDKYGFLISQSYSEDFGTPGTGSTISDINFTGSKTTVTTSGNYPRVGVDCGECTGTWNWAELDATGGESSDLVLGGGVVVELTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY73</accession>
    <name>A0ABQ8VY73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">COQ9 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_363884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COQ9 C-terminal" evidence="1">
        <location>
            <begin position="143"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="234" mass="25509" checksum="695A820828C7BDFD" modified="2025-10-08" version="1">MALSPSRSQLLKIATSLVPTYGFTRETLSRSVLELPKDKAHSEPLSENAVSSLFGSRDYAKKTLIEAWLSEGITQMASAPSPSLGHVLHARLSYNEPVLHYLPEVSCSSYKSDSVAEMKNILQAFALLASPERALPPLDPRPALKHVSRIADEASYISGDDSAQLSWYTRRASLATIYSAAELHQFTSPGTAHAFLDSLLTGSSALKQSVDEVQLFSSYVLQSWKGILRSKGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ80</accession>
    <name>A0ABQ8VZ80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_748173</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="9">
        <location>
            <begin position="173"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="728" mass="81995" checksum="37B2D63D114FF600" modified="2025-10-08" version="1">MDTTPPSSAIPRPDPRNLTSLPQILSSLSDFESQEAELSTSLTDLLAASEPITQSLSRLQSLAPQLDDLLKDASILSRNVSSTAKTAERIGGRVQSLDEEMRRIREASDRVGQVIDLKSSLTALQSSIEASDWESATRHCARAMSLPSEVISGSFAEFAVPTSESHLPPAQTLQEAREHLLHVFRLNFEQASRSRDSTATSRFFKLFPAIGWEKEGLQAYATSVVDSVRVKAPTSAKTSSPLYFIAALTSLFESIAMIVDQHQPVVEKYYGAGKMKAVAERLLDECDRVVKDVMSRWQEERSITRKISDITNNPPMSSMVAAGRRPQASSNQDDEHIDPREIDQVIIEMSGMVGRWNLFKKFLLDSFEAPDTTSASLPLDSTASQMVFDEVLVKYYIPLEVWYVRAIIDKAHRLSQPDMTQSATTTTTPDDVFYILKVVLLRLSSTGSLNAVERMTEQLCDILEKDYAVVLKKKMDEVYRSAGATGQLVRGEKADRENRLAFAVILNDLDVSSSHLERLIQDLLGNGAINQYFLSSQQQLVKDVFASLSSLVTKFRSTSRVGIEQLFNQLIRPKLRTFITEVYKDVSYVLDDDSYSNAEYQDFVRKRFMKSWDTLMDDYKDSFTEANFRILFGLVLDTLLRPWERFMMGFKFTELGAIRFDRDLRSVNTYLSSQTAFGDGREKFVRLQQMSTLLNLDSEEDVDEFYNGSGITWKVSLQEARAIAALKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZT2</accession>
    <name>A0ABQ8VZT2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_892665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF3">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="304" mass="33095" checksum="B7CBE403A3F2153F" modified="2025-10-08" version="1">MKILIFGASGFIGFPAAQALIRAGHIVYGQTRSKENVQRFEAEEIIPVVCEPESNAWHSLLPTLDVVIEALGGTAIKQFVAASIREGVASAAQQFRPSHAPKLTYIYTSGCWVHGDNRSEIVTDTTPITNPVELVAWRPEQEQAVITHSTLNGIVVRPVMLYGKAGSIFASVFKQAKEEGKVTWPGTPGGKLSVIHADDLADLYVRLTEKASIVGGKIFDVSNDVLEDMDAFLKKLSQIAGLEGKYEYRNPTNIFEVAMGTTVLARPYLGRALLGWHPKKIGLTDGLETYYASYLASVAESKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0S5</accession>
    <name>A0ABQ8W0S5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_1345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="844"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="765"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="911" mass="101296" checksum="7D12312560E3FD30" modified="2025-10-08" version="1">MKSFFQRKNDSQTGPSKSSSSKDPYRIWMPRQEPETSQKPLERSEKREGRSGTRDSSEKPRSSSRAPRPSDTGATISGAHRSHRHHNATPINKDDNVVHPASVNSTAPLPQSQRVAQAYPKSTVPVPSPSAINASYASHAATRSANPAKTYTSSTFNGIYPTASTSTSVAPAVVRPEMAKASSSYSKRDREPSDRHGDRTRDRSERERMRDRDYDRAKEKERTRDRTERDKGTVKERDLTKDRDRERERDVERTRKRERDRERDRDRERERDRDRDRIKPPAEPIPTAERGLRERDRQRDTDSIFRASVRDKDRTKYRERELPRTNDRTLAYDLGREKLIPKDADKYRESSRRHLDRDTERRPDVERSSRRRMTERERDPARSFINTQKLTSKESSDEAESSDASKNKYSSAYRRTKIKDPIPNISTSVLPPASAGQSYMPSSKDPTSYGVSVPPSSQLRQDFAPYGSQSMPSTLKANQDLSAYHPISSTSRPNQDSVYHGGAPIPPTTKSIHDSGPSNSMSSVPRPTQDATFRGAPPVPPTTKSIYDSAPHNSIPSMSKHNQESVPGGGLSIPSTSKYINDLTPSQPVFSPEPLPIRLPVRIADNSLFREPPLPLQPPINNVAPPLNGVQRTEKYHSTSTNFRDKAQNPTINSSPNQQRDADQSSPSTGRPIGNNISQGPAPIHPTMEMSALGLSGTQALETNGQFSSYPVRTKVAEPVYQEPPDIRATSSRHERTSKHRHTEQSPAGTSALSGVRTRKASSTSQQAAPPVAVTPSSTTNPTNSTNPSHSSRRERDKGSKSYGIAANEPRTRHDANSINLQNPESSPSLLFQESQIANQTNQLPPTVNSSPHPSIRFTPPTPVKRSPSVLERPVVNTNYLSSSNAHAHAPVYHGGTPKAVTRAPEVCCSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A9W1</accession>
    <name>A0A9W9A9W1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8J55DRAFT_96695</name>
        <name evidence="8" type="ORF">C8R41DRAFT_158984</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Cytoskeleton</location>
            <location evidence="6">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ARPC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000019">
        <property type="protein sequence ID" value="KAJ4477056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A9W1"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000001">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4477056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="170" mass="19501" checksum="94828D13D152D05C" modified="2023-11-08" version="1">MSNVLRPYLAAVRSTLTAALTLENFSSQVVERHNKPEVEAGGSKEVLLNPLIISRNENERVLIEPSINSIRLSIKIKQADEIERILCHKFTRFMMQRAESFIVLRRKPVPGYDISFLITNTHSETMLKHKIVDFIIQFMEEVDREISEMKLSLNARARIVAESYLTAIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AZ84</accession>
    <name>A0A9W9AZ84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shr3 amino acid permease chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_500949</name>
        <name evidence="3" type="ORF">C8R41DRAFT_830370</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000004">
        <property type="protein sequence ID" value="KAJ4492675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AZ84"/>
    <dbReference type="OrthoDB" id="5229808at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013248">
        <property type="entry name" value="Psh3/Shr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228:SF1">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08229">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00786">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="176" mass="19292" checksum="1D7F2D463D4D1276" modified="2023-11-08" version="1">MTFKQAAVLAPVSFFLGILFICFNVDHKLLWGELTETVIADGFSFYTTFFNSPPAIKALLHGMIGVGVLGLVGKLHKWDDSAMFFDGSSLGVYVFAIAVYTAVICPTLKTVAIPLEEDTYSDRIEAVRVLAAANVIIMICLGLILTLQAGQVYAKRLEVQAIEVENKALDKEKKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9E0M5</accession>
    <name>A0A9W9E0M5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">CAAX prenyl protease</fullName>
            <ecNumber evidence="15">3.4.24.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8J55DRAFT_499492</name>
        <name evidence="19" type="ORF">C8R41DRAFT_749849</name>
    </gene>
    <organism evidence="18 21">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="18" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Proteolytically removes the C-terminal three residues of farnesylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 15">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic side chains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.24.84"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14 15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 15">Belongs to the peptidase M48A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="15"/>
    <dbReference type="EMBL" id="JANVFS010000003">
        <property type="protein sequence ID" value="KAJ4493669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9E0M5"/>
    <dbReference type="OrthoDB" id="360839at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.10:FF:000002">
        <property type="entry name" value="CAAX prenyl protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10120">
        <property type="entry name" value="CAAX PRENYL PROTEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 15" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 14 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 1 N-terminal" evidence="17">
        <location>
            <begin position="47"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="16">
        <location>
            <begin position="234"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU366005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4493669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4501099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="461" mass="52863" checksum="08EFFE37E5A33825" modified="2023-11-08" version="1">MDFLHSGLADVQRHLAFVSVDPINWKFYVQVFSWSVTIFESYLLLRQYPLYSKTSPPEALAPHISKEDFAKSQIYGKDKAQFALFSKLFSQCVDSAMLQYGFYAWCWGAAGTILGKLGYGTDYEILQSIIFSFTMYLLSSLPTLPLSVYSTFVLEEKHGFNKTTPALFVGDLVKSWLIAFALGAPFLAAFLYIFQWAGDRFVPWLMGFMISFQLLMVILYPTVIQPLFNKLTPLSDGELRSRVESLAGKLHFPLKHLYEIDGSKRSSHSNAYFFGLPWSKHIVIFDTLMQQSKPEEVEAVLAHELGHWYYLHPTKMMAISQFHIFTILALFPAFLHAPPLLRSFDFPKHVAAKPPTIVAFLLFQMILTPLEAFISIGMNAVSRHFEWEADRFACELQDQLKEESMKDMGDRLGRALITLHVKNLSTVWVDWLYSAYHHSHPTLTERLKGLESFQAKRAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVV1</accession>
    <name>A0ABQ8UVV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_712119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000181">
        <property type="protein sequence ID" value="KAJ4463305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="269" mass="30015" checksum="ED909E9732F11945" modified="2025-10-08" version="1" fragment="single">AYKFIAPVQRLEKVNDLVDKILNNDICVKASDLLSTSKPIREELKYRVTQQRVNSGEQPKSTQVKAQFEELQLDSDTINIDSLPSVTWEKKTERTNSGEQMSAFVVGDVVLQYLETLAPKETAKQIVVAKDSQSLRSIYPLLNGREHVESLLDSGSQIVSTSQEKAEKAGLIWDPDIVIYMQSANKGLEKSLGLARNVPFLIGDMTVLLQVHVIKEPAYDLLLGRPFDALLQTHIQNFADGRQIITLTEPLTNRRITVPTFARGTAAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVV4</accession>
    <name>A0ABQ8UVV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_169440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000177">
        <property type="protein sequence ID" value="KAJ4463320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="163"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="709" mass="81453" checksum="275FD4B1CE5A5A42" modified="2025-10-08" version="1">MPSSSPRKSDSAYPPYDGTTVRQSEMRSRIKRDNADNLIECSPRTFLKTYASNKQLRSKDLRGVVMNALQEDKLLDDNGWTSLRNMGKGQNENETFAFLSQVAETITSAATKHDTTLEPQAIARPSPTATSQHSKPGYRFYPDWTALSSSIHVDAKPSKLGASRKTSVKTSDIASIAEFKLEDTTEKIIDNEDKMAGAANQLLWNDPCRERVLGFTVEKKRTRFWDFSRCAIAVSEPFDISEKPELLVRFLLFVIFAKKHEIGFDPTVHRISVGGEDCYCYEIGKSFFLTVGSPLSEEAAYRMVGRATRVWVVVTLFPDSNGDIEVGGRRFRRGDARRVLKDVWLYDEALCEREIQTSITEKLNKEQKAKLKKHFLTFIMEEVIVFEGEPRLTPRPQNGEFQSTAWQTDPYFHQNSNPSTSRGTREKPPRTEVQPIMMSRTHTLRKHVRSVVREECESLYQLTDFKNALICWRDMIICLDLFRIAGFIHRDLSGGNTLFFEGRGIISDLEYSKRYNEVSSHDPKTGTPDFMAAEYQANYFFFLPSPTDTTAQLLKLQRQWFSPHFVHDIESVYWQYLWFLHNRIPKTSEPSQSALEEIKQQAKLYFGYGIDGNHDRFDVIRNEASNMLLRGVLESVYRPLILQLLDLSITLREEYRRVVRSLPMKKSDDAWRLGDVFNGDIYEKFLGNLQAMLDAYPDGYAVITLDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWT8</accession>
    <name>A0ABQ8UWT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_131007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23422">
        <property type="entry name" value="beta-trefoil_Ricin_MPL_CNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="6"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="284" mass="31665" checksum="EA16BE871DD69EAE" modified="2025-10-08" version="1">MLLLKPGVYRLVNLQSNTALDLSEGDGKSFIGWTKHDNPNQQFVFTPLGHGGGYLIQSAWNGNYATTEDGICTGTAVVGSGFPVTWALEDVTPEMHETYAPRSNGACFRIRWPNSRYVFDLEGYGCDKDGTRIQLAYEQNPVHPCQVWRFEEISYTVPLTSGVNVDAVTPPAKFDPGLEVPEGRLVDDLEDESDEDSDYGEFQDASEDGLELELISAVTSINSTPTNKEDKEVEKYKIRRFFDYPDEEEKGSLRQSHIAGIMTTSSTVMTTMAYKNMYSTKPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX87</accession>
    <name>A0ABQ8UX87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_181883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000186">
        <property type="protein sequence ID" value="KAJ4463255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="302" mass="34924" checksum="E24EB3ABF009C95F" modified="2025-10-08" version="1">MLFHSALQTLGIVAGVFFVASFLASVSARPYTTTAHLVFRKTGPSQDCRATILSSKKTFLDKVAAQEYADEWCSQLEHESWIQYSASSLCRGFDQFERVFMDDVTEFITGRQFSRKGENNLGIFTLPNHKLEHRIVKFVNISEGHESAACEKYSLLDFGEQVITGFTTLDKEKVGVIIMPRVDGTPLRDTHWWRNISKDQKLYALNSTRKAVEKTVLDFLHEGKSLYTNFSPNRVLIDDDKGVDFIGYEYPGIWPINVLPTKDQFDQWFDRRWDFLWGDVYREVDKMPEYQSGLERNRARLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY34</accession>
    <name>A0ABQ8UY34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_858281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000125">
        <property type="protein sequence ID" value="KAJ4465578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032870">
        <property type="entry name" value="ALKBH7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052:SF0">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052">
        <property type="entry name" value="SPERMATOGENESIS ASSOCIATED 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="241"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="414" mass="45561" checksum="54D58FA4D03FE04B" modified="2025-10-08" version="1">MKRKPDLVESIIESNSQKEENHHGKRMRFHVEIPTSLTTTLDTPQGNASETPNDIDVDTFSSLSPDSLFDEAFTFPSSFPASPPLHLHPDEKVQIALRTAPPIPGLFFDPSVRLSEDLAEELAGYCMGRYFNDDDGKRRVNQVMLFERAPVDQETVTEDAVSCGSGSGCPTSTGLPPPLLALLDKISDLIRPPLLSSKTHELLFPSFALYTGTGRSEQVPRSGHSATSTSRIETHSKQTKQARQAILNLYAPGEGISPHVDLLRRFGDGIIGVSLCGGCVMRFERIREERVEEVAERASWQSRSDSPSSSVDSVFLSNSNVHELYLPPNSIIVLSGEARYKWTHGIERRTGDWVSYGDEVNVGDGEGLPQATPNDSNLGVKVEWIPRTTRLSITFRWLLPGADIVGGDTSDCEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY80</accession>
    <name>A0ABQ8UY80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF1">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047206047" evidence="1">
        <location>
            <begin position="19"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="301" mass="31236" checksum="FB2E07D7AC9EAF9B" modified="2025-10-08" version="1">MKSSSVIAYATLVGAAAAFVVPQARESSTNSTTSDDTSLLNYVLTLKNLENAFYAGALNSFTQDDFVNDSLPTWSRARFEQIAEHQQAHVDLLSNVIGSGAAQACNYTFPYTSPSTFAALAEVISGVCVSAFVGAAQYITSSDYLTTAAAILSTEARHAAWIAGPVNHQNAWSGAFDTPLSLDAVYTLVSQYISGCPSSNPTLPVTSFSSLTIANASLGQASTVTAANNVTVEGQYVAFISGLTPTFVQVVGGQVVVPATIMGTSYAVLTSSNTSVDDSTITAGVVALQFPYNSNGALELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYH5</accession>
    <name>A0ABQ8UYH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="302" mass="35186" checksum="60168082A5EBB8AF" modified="2025-10-08" version="1">MYDILGFSGEYLLPLRMPSIEIVLGHDALGAFALIEAHFDKIMENVAKKQWDAVYVLLDGFVMYNFRACPKPMDILDTKRKHGLLKVYGACVVTMLRELDKLGRLNVQNFPGLEYFLRYTIEWTEWAKDELVNHLHLRSDILPHLGVCKAIAHRLFKDQTVEDHTLHLARIREWVRWLEPRATEEDHDYAGTKGWVQDWLIQEWPSLLLGVNPWYLAGKDDNSLLKDPRLDLALEWDSFSNYRQEKPLVPPKGLSWEFKDWSKEDRDAHRDGTVFEIPSSDGDGDGSDKESMGWGMEHSFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ79</accession>
    <name>A0ABQ8UZ79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein serine/threonine phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_898321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="5">
        <location>
            <begin position="78"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4466734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="56436" checksum="1A396B04255D18FB" modified="2025-10-08" version="1">MLRRAWKPIAASVVVAGPAYYFYTTHDQTFELPVRVKDSDGKKQIKMKTLPLLPMTSINSSLRESGTAETKSRPYGVTWHHTTSALASNDPIEDAHSHQIIQSDDGKSDLLFFSVFDGHGGRNTSQLLSRTLINAVALKLSQLAASTTASSSTKSYTDGLWEIWSKSPSNSTPTSWDVPSISSAIENAFVEFDQVLLDAPISILKQTLQEGNLTAKSPVPDLSSNASGIQTMQAAISGSCALMALFDTAQKDVYIACTGDSRAVAGVWKPTADGKGTWEVDVLSEDQSARNPKEVERLRSEHPDDEADNVVMNGRVLGGLEPSRAFGDARYKWPIGMQELLNQVYMAGNGTPLRKPPRTFKTPPYVTARPVVTHRKLSFEDPSSLRFLVLATDGLWDVLTPEEVVTLVGGHLAGLKGTIPKSTLPSLVPTSVANAGVDGKAGKQLARSTKQGSWAFVDDNLSTHLIRNALGGGDEKELRQIMSIPAGTSRRYRDDITVTVVWWEAGKENEAESVIVKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZA4</accession>
    <name>A0ABQ8UZA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_856243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="170"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="347" mass="38932" checksum="E9803AF7C7F1EDAA" modified="2025-10-08" version="1">MIIEGLSPGPLPPPKTIEHRFQDPNYSNAYTSVYNFHERVLGDEASVIRARLLGFLLILTTNDTVRAEVVSTVVSCSNDSALYDLGELYMDFFICPFMKYKGPRTPTFQSHPNRPFDLREQEIESMIHQAPGNHEKAKDLALYRDGYRCVATKIFEVDHAVNGGPETYADIQQFGATATNCAHIIPASTYIKLSNETKKDYAASVLAVLARFGYNMDNLGWPKIHPLFNTMTLVTVVHDYFDQLKLWFEATTTPHRYEIKCLNPFEPILRNMPSPFTTFTTSDPRLPLPDPALLALHATCAKVAHLSGAGEHIDRVHRDLRRLDVLAEDGGSSDVLFHALSHSSLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZI4</accession>
    <name>A0ABQ8UZI4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_858397</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="5">
        <location>
            <begin position="543"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4465465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="759" mass="84810" checksum="A63C35ABE6E97B2F" modified="2025-10-08" version="1">MRFSFALSALGLTSRSQVPLQPNLPNPVAMAMVQNSFQFKEGADVFTPKDLVELGRPGVGVANQAGDFVVIPYSKYSFEEKKNHKSIYVAPLESTVKPFKLPLVEGGEAFWLNGRTLAYVVESEQKNLEIFALDVLYQPSTNDSAAVLSTNAPILLGSFPTTSASNFRYSTDGYLVFSDSVYSDGNLTTVKEQDEAWENRGNTALVYDRTYERHWDHWVGPKTQSLFSVGLVQDPNHMWTFGSEFVNLLAGTGHSSPVEPFGGTDDFYVSKQSVIYTTLDPAFEEERAWHTKQNVYIVSITAAGKPRELTSGSQGATRSPVLNDAGDKAAWLELDEDGYESDRAKIVIYDLKKDVRFTLTQKWDRSPGSLAFSKEGDFIYFTADDHALVKVFVLPIPSTPAKSTTDPSLSPKYLNPVTIVEDGASSGLQTLPYGRILISKSSFTSPNDVFLVKGLDLLQAQMTQSDGTAKFTGEVDQVTNFTAPDLEGKNLSKGENFWFKGANDVDVQGWILKPKGWKHGEKKAFPILLLIHGGPQGAWEDQWSTRWNPNVFAQQGYFVVAMNPTGSTSFGQAFTDAIAGDWGGKPFVDLQKGWKYVLENYPEVDADRAVAAGASWGGYAINWIQGHPEFDFGFKALVCHDGVFDSNYNGFSTDELFFFNHDWRGRPWDKNSEEVLRKFNPANYVHKWSTPQLLIHGSKDYRLPETEGIGAFHALQQLHIPSRLVIFPDENHWVLNHGNSLKWHYEVLRWFDQFVGKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZJ5</accession>
    <name>A0ABQ8UZJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_927039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000143">
        <property type="protein sequence ID" value="KAJ4464281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="19790" checksum="74B6618535AA4AE2" modified="2025-10-08" version="1">MSSGPSSDEQLIQAILSATDIVTIKHRGIDDASQSTMLQLGISSSTVYVPEGDSSPPAQLAGSEEDQFLKRLWQQPAILELLRGPRGVNLRQQWSAQLNFLIAIDFIDEESVVFAENTVSMVIADLLALVVVDLSDIQFEHMGRWRLLSPYSSREKETKADLLFGLHLEDTIKQFDVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZU6</accession>
    <name>A0ABQ8UZU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_803569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="59346" checksum="97E6F29329A6C92C" modified="2025-10-08" version="1">MVLIPPEVQSLIIRDLDPQGRSRYSLMNKESYHTVNNFNQRAFRIEQVLAPFFDQKEIDELRLLQYRTGILISGSTALQFFDLVVYPDSDLDLYVELRHCRPLAEFLADVGYQFQPTPRQRSTFDEALAFTLSLNFAGTQNLHDEEEDFQGYVNNGIASVYNFSRGSKRIQVITSHTCSMDVILSFHSTCVMNIITYSHAYALYPRATFLDRVSMTNALFSTQDHRHGLARAKYAGRGWTMIERPSIAMSLRQRSEFWFGGRSVGDAACWTIPLSPIKNISVRNIDFACINSWSHDFDVYKSRLVRCPRTHIKLKYGYSLSQSTKTLEELFKSLDYMHSSLFRRVHEASTDEDSDSIDRQWAALVHLFVDENLKAPEENPRIEQIRAQLVDVYTNQIPTFEHRKGLITPHAMTVSTLLGELIELDKFFLQSFHDNPTYEFTFKLSDYTNYIWTNVKVILPPEHERKQGDEAVNNKMINKMITKLKSRKVGLTIDGYPGNPTNCLRVAVPPLVSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZW3</accession>
    <name>A0ABQ8UZW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_96324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32706" checksum="D070C8922197E10E" modified="2025-10-08" version="1">MSSNKQSASGERSPRSMDTSQSEQFEHSTTISGVFFAGSRNFEITGGSFNHAARDMHQTVNNDNSKQSDFNNDHRDAATYNGAAMHNDRKGSTTNVAMATTFATTTSSQRQIPRNFQGQQMSVLRKNYAALESHPGYNIEQTLGNLNGNDREFAAAEYAENTRVQAQQKLYFERQKHDGFEVCVITERTLSRVNNKQMTMKGPGDRSTADVNMETADSEVEDSGKAELRQCVQTLLANAKQKDLPGLANALIDAGWDRETLMDAHWDDIKGSYPEWQPATFVKLRTICVKWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V161</accession>
    <name>A0ABQ8V161_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_855790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="31469" checksum="52E2BEC2A8B70CD2" modified="2025-10-08" version="1">MENYLPINALSAAILVSGKIDSKEQWTGPKIPVVLYRQDPPPANILDDAYTREGDPDYTDSYPPCPSPLFEIPSPAGLTLHISLGKLISEGRTGMIYECECAIPHGNEMDYKIPPMVIKIAKQFRTKDITKEATAYECMTCIQGSVVPRCYGFFQARMFDYFDFGPVSLLVLEKLGNLFELGEPLPNGAMTDMKDACSDLMNLRIIHGDLRWANMLSVLEGGLPSLPSPFTGKTYGWRLIDFDRAERTTQNLPCVQRSYDEYLNRVLESIPWGDPVEPWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V175</accession>
    <name>A0ABQ8V175_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Telomere stability and silencing-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_54286</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053822">
        <property type="entry name" value="SDE2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024974">
        <property type="entry name" value="Sde2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF1">
        <property type="entry name" value="SPLICING REGULATOR SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22782">
        <property type="entry name" value="SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13019">
        <property type="entry name" value="Sde2_N_Ubi_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sde2 ubiquitin" evidence="10">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="SDE2-like" evidence="11">
        <location>
            <begin position="81"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="152"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4467279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="28243" checksum="F46B4AB9EFED376D" modified="2025-10-08" version="1">MITNVLVSSFAPFGTLTLAAPSVTQISNVLSLLTEKYPLLPSSGLILSSHSGITPEDTSLASLCENGPNLISLRLSPRVLGGKGGFGSQLRAAGGRMSSQKTNNNDSCRDLSGRRLSTLKEAKKLAEYLESEPERLAAKAEAQKAKLEALERRLGIDNPSTGAGPSRTGSSSSEQPAKLAGKKHRFDDTEYLEQSRELVENVKSAVSAEEEKGQVVARLQVANRRTVFKDSSSVQDADPCSCTPCPNRGRRCLRDNIVHVHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V219</accession>
    <name>A0ABQ8V219_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_781045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007224">
        <property type="entry name" value="TIF_Rrn11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04090">
        <property type="entry name" value="Rrn11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="22537" checksum="FABD07238CD5BAD5" modified="2025-10-08" version="1">MQDAFLFSAPASNLNVPLTARKVHIRRLYEVLQLSIHRNDLPRARRAWSILVRCKEINWTTMWNTAIHLVEENSYGDVSAKRIELLRDMMLHYPDQRIAVIKELIFQLILSGRHRGALDELELYLPSFPYQDSPVLHIYAGLLCFYLSQEHSNSEACAYLSALSALVREAMAHLERAQVLDPGNIVAVSFLHKVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2A3</accession>
    <name>A0ABQ8V2A3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metallo-hydrolase/oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_853718</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4469011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF2">
        <property type="entry name" value="102 KBASES UNSTABLE REGION: FROM 1 TO 119443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="46"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4469011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="297" mass="32868" checksum="E92B2A460A170C67" modified="2025-10-08" version="1">MQVNPLPLPTQDQAYCIVSALESGHIDVPLEVFLDNAVPGSQATLPSLSFLLRHSKTNETFVFDLGFRKDLENYSSSIVKLGLEKFVRVPQDVVDSLAKGGLSPLDIKTVCLSHCHFDHYGDPSHFVNSEFVVDADSAIHFNPGFPADPDSQFPSDLLPEGRTRFVELSDQPFLGPFPHALDFWGDGTLYLVDAAGHLPGHIVLIARTSPDGGWILLGGDSAHHWNLITGESQIAEGRPGFPTGCAHLDKKEAELTIQRIREFWQLPRTRVILAHDEPWYKENKDGASFWPGHITSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2L1</accession>
    <name>A0ABQ8V2L1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_707759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="118" mass="13495" checksum="003EA449CB96D7BE" modified="2025-10-08" version="1" fragment="single">VLERVNQTIREVTVPSWISKPSEYIGLPKAGTPKANNWRRLFTIFLPLALLSMWQVCSPTAASDAMEMSLVLDTSLYLTCEFESTLLHSFCKGSAFRRWLLRPNCPPLLRVLRQLLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2P0</accession>
    <name>A0ABQ8V2P0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_924745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4471013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="56"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4471013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="491" mass="53335" checksum="F60B46882B2D3E11" modified="2025-10-08" version="1">MNSRALPMTRVNGHTDANSHNDPGAAPEIVSELNDIDLVEGRQHFTKPPTKTYQAMLLLAGSMMIFHVIGINQVFGIFQAVPHLPEKEFYTSSRSNIKDAQGQDALVSLVGSIGAGLTWSGSIFMNPLIAKIDNIKLVTFSGAFIMSLGLILASFATRIWHLYLTQALLYGLGSSMYYFPLMTLAPIYFDRHRGFAMGTILAGSGVGGLVMALVLQFLLDHYGIQWALRILGVWNLAVAIPVSMVVRHRVGYGLGAQRQRGSQNRTRTMVNNALLRKGTFWYQSIGAFLQAAGNVVPLYYMSSYTVSVLALSNSKGSLFVSINSGVNSLSRIAMGLLADYIGRQNTLISGAMLSAVSVFALWYNAPQARFIAFVVMYGVYAGGYNALLPTTITEIYGVENYASVNGVMYFIRGLGSMFGAPIAGLILGSHSRSPSLSNNGDSTSTVGLGPIKRRFNDVVIFDGMLLLAAAVCVGYVRWLDARDKGAWRWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3G5</accession>
    <name>A0ABQ8V3G5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_776295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="239"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4472420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="50905" checksum="823FF79BC27366BC" modified="2025-10-08" version="1">MSSTQPPSEPPSNPEKQPEAPEQSSPNEQTQDAAMDTTPDQPAEDTFDDLSEDILSLGTDEILTRIRLLDNDIKVMRSETMRLQHEQTVMKEKIRDNGEKIKQNKVLPYLVGNVVEILDVDPEGEEDGANQDLDSMRKGKCAVIKTSTRQTVFLPMIGLVPPEKLKPGDLVGVNKDSYLVLDTLPAEFDSRVKAMEVDERPTETYTDIGGLEKQIEELVEAIVLPMQEAEKFKTLGIKPPKGCLMYGPPGTGKTLLARACAAQTQACYLKLAGPSLVQMFIGDGAKLVRDAFALAKEKAPAIIFIDELDAIGTKRFDSDKSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRIDILDPALLRSGRLDRKIEFPLPNETARARILEIHSRKMTLSEDVNFEELARSTDEFNAAQLKATCVEAGMMALREGASKLTHEHFLTGIAEVQSKKKNDLMYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3J0</accession>
    <name>A0ABQ8V3J0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Remorin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_591801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38896" checksum="15CADFF9112FA949" modified="2025-10-08" version="1">MSVVSLRTAREMHDVADLLGSTIDAPIDRPRHERAQSDETILDPSIHSPTTDDESDVDKHSTSILSPSRSRLSYASTYSQPSEFELVTADGQIERVYLPPSPSFSGFNIPRSRTSAISETPSLASSRSRSSYSSTSSHQLPPTPGIITPAEFADGNLLPVIVEKQSEGQEWSSNSSSEEISALRVSPPDTLVSSWPKQKSILRWKVPISPRRDAITEEVRRPDSPGQWSPSFFDTLTPTSQDSPTTPSPTSPSTKTSPFSLFTKREKGSRSSLTSSISSQVSQLPLDNKAMKAEEKRRRKEEAKARTERLAEQLKAKSKERARMEADNISNFSAERRKKERGAMYGGIAGVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3R6</accession>
    <name>A0ABQ8V3R6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_853338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4469145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="353" mass="37588" checksum="4BEEE3E41118A80C" modified="2025-10-08" version="1">MAVISTPITEMFGIQHPILLAGMNVAAGPELAAAVTNAGGLGVIGGFGYTPKILRQQIHAIKDDLVDKSAPFGVDLLIPQVGGSARKTNYDYTKGKLDELIDVIIEEKTALFVCAVGVPPKAVVERLHKAGIPVMNMVGHPKHVQKALDVGVDLICPQAGEGGGHTGDTPASVLIPACVDAVKGRKSPLTGKPVYVIGAGAVYDGRSLAANLMWGAQAVWVGTRFVASKEAGAPKYHKDLVVSAGFDDIIRTIIFTGRPLHVKKSAFIEDWEINRQAEIKELTSKGIVPSDWAVEQRPEITKDPESRPWLMGKVAALIKDILPAKTIIENMVNEAAELLEHGSTLVVKTKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V471</accession>
    <name>A0ABQ8V471_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_924391</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040909">
        <property type="entry name" value="CHFR_Znf-CRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052256">
        <property type="entry name" value="E3_ubiquitin-ligase_CHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079:SF4">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079">
        <property type="entry name" value="UBIQUITIN LIGASE PROTEIN CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17979">
        <property type="entry name" value="zf-CRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="81"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="428"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="434"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4472373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="468" mass="51678" checksum="9F204036C7E34CE7" modified="2025-10-08" version="1">MAEEEFKTDSDPQYTGNASLTRNSSPRINALSLKRPASPTFEDQDSRKRFKESEGSMDNQCKEDGGTGSQLVDEIAQELECGCCSELLYKPVMVSPCQHTFCGSCCLLWIRNGGTNCPACRAISTTASPSRPLQLVLDALLRNAPQKARTEREREQADVIYKSGTTLRFPSPREASPEPNVNISAEYARPCPHCSPNNTYGWSCPLPIPDPAVDLEHAWHLDDGLPTGHVQCGNCETFLALRAPSTTRCDFCQTYFCGVGVPSRCSAAPIPLQQPHGFTDIGDLIQSSDVYECFNSNTVEVEIMLDYITAQGLSPRHIYRDIVKYILEQPRQFRPLIEMELFIVSHVGPRVEADSSASLHRICRSCACEIFIWGIKDWWIRERRKGFLEERIMNRKDCPAGGGCAMQSEFGHAKEFNHIDGKPVGFAAHSSGSTTPTETTETTAVTEGYHSPSISESIPAVPSAPVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4N6</accession>
    <name>A0ABQ8V4N6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase III, subunit Rpc31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_848101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC7 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024661">
        <property type="entry name" value="RNA_pol_III_Rpc31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11705">
        <property type="entry name" value="RNA_pol_3_Rpc31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4474159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="16192" checksum="962DE5E8C95C027F" modified="2025-10-08" version="1">MAGRGGRGGGRGRGRGFGAGALPPMGLSFADIQTMSREATALYPPMRAPVMNEPTEKEKRITQLQIEFASRLRKSEYYLVESTKSTELPRYSDKYRPSTTSQPALKRSELHAPFFPPEIFEAYFNPKKKSKGLNGPLYFEHDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V515</accession>
    <name>A0ABQ8V515_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047245258" evidence="1">
        <location>
            <begin position="30"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="22887" checksum="C7B0122C27951828" modified="2025-10-08" version="1">MYSTLPCLRTISALSIAIFLFASASPTRAIPIRIAVYVPAAIHLDVEVTGSQLNHDLHSIASSPDIHLDVENDSVHQSEHALHASAPVVDVHPNIELVGSRPDHANVPAAVTYIRPDIEEPSSKYSHHDLDYNHESHDSSLFHERLVGNAKTHAMSAPHPGELNHLNDGVVSGLKISSHNPFRALNHASSHSDSLVIQADTVTSSAEDVDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5A8</accession>
    <name>A0ABQ8V5A8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_897969</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF7">
        <property type="entry name" value="DRUG_PROTON ANTIPORTER YHK8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="52"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4469333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="482" mass="53804" checksum="B84A900A4AB4F3C2" modified="2025-10-08" version="1">MTSLSSVLTDCLWRRVKTELKEEVVELETEYEVDLLPEEHPQQLPLWRKWLAVVVVSCCSFCVTGSSSMAAFTETAVSEDFHISHEVAVLSVSLFTEGMALGPLLTGPLSEMYGRNITYRASFTLMFAFSFGVAFAPDTAVYLIFRFLSGFVGATFLSVAGGTVSDLFKNEEVANPMAFYTCSPFIGPIFGPLNLNWRWTYYILTIWIFVQTILLYICVPETYAPILRKWKAARMRKSTGEEAYWAPLDKQDKDVMKAMLVSFYKPFELIFYERMALLLNLWTSLVLGILYLTFQAFPIIFTEKHGFSIEQSGLTFLGIGIGIVCAMPTQGYFNKLVVRDAKRNGGIAPPESRLYMGEIGAILVPISLFWLSFTTYASVPWVVPIIASIPFGIGLYYVFTAVFTYLVTAYRPLAASAMAGNTAMRCTFAAVFSLFAGYMYDGMGTVGATALLAGIMSVMAPLPFIFRRIGPRLREKSKFAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5U7</accession>
    <name>A0ABQ8V5U7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_552379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="154" mass="16884" checksum="611FA07EA7104B8E" modified="2025-10-08" version="1">MRFPLFGLNMKACLVFILGVLFITYVTARPVAGLEPDLLSRSNQLVKVHISFPGGTNEFLQSAATRNVREAIINTLEAYTPPGHEIEVIFPTPLRIPAFNKVHEIDFRITLDNGAAGTGLVEAVGEEPDYEDGPFVVRQHVLAQLIAGMVKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6B5</accession>
    <name>A0ABQ8V6B5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Small ribosomal subunit protein uS4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_897896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="8">
        <location>
            <begin position="4"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4470046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="184" mass="21545" checksum="8B7A08D03A496A17" modified="2025-10-08" version="1">MVRKLKYHEQKLLKKVDFLNWKQDANLREVKVMRRYHIQNREDYHKYNTLIGHLRSLAHRVSLLPPQDPFRSRTENQILSKLYDMGVLNSSAKLSDVQNKLTVSAFCRRRLAVVMCAGLKMAETVSAATKFIEQGHVRVGPDAITDPAYLVTRRMEDFVTWVDTSKLKRTIMTYNDELDDYDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6L9</accession>
    <name>A0ABQ8V6L9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_527392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27328" checksum="AB84B266CA00BA2F" modified="2025-10-08" version="1">MASSATSSGSPLKNTTKNARKYFKKFLIKVRKRSPSPTPSRTKSRTPPSPSTPTQFSKVNNSTKAPPTTWKVILDTPRTSRKARLWAIVPQFTVAAPDIPGVSKPDWAMNGVNDKARRFHTHGKVVIDNDDDDFSVNEQSTLAQPSYLISPCIASGRSEFSANSERGVAKCDVTQLEYPCQAAHAIEMSYSMEARLATYFALRGWISPNSRINYLYCVSFHFPEDIVSAHVLQYETIFIFDWIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V766</accession>
    <name>A0ABQ8V766_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_849722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="71" mass="8030" checksum="93D38677F0689675" modified="2025-10-08" version="1">MNFELRLHLFIVFLISPLLRVLKERLPLLLASLPVLPDFSCIRAAVTIYILNLYILTCLAPSALLGAWAHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7E8</accession>
    <name>A0ABQ8V7E8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="3 10">5.1.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NAD(P)HX epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_775943</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="3 10"/>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032976">
        <property type="entry name" value="YJEFN_prot_NAXE-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232:SF10">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="11">
        <location>
            <begin position="11"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="134"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4472722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="235" mass="25810" checksum="13A46B4BA1EE52F3" modified="2025-10-08" version="1">MSIKYLTAKLAQQIDEELMNQAGAFSIDQLMELAGLACAQALARVYDKKMYPNVLVCCGPGNQGGDGLVAARHLGMFGYTPTIFMPKPGSKEIYQRLKSQCDNMKIKIIPPSEDTSLLRDALSSSNVILDAIFGFSFKGPIRAPFDTTLSLLTDSHLPIVSVDIPSGWDVEEGKIERIGLQSDVLVSLTAPKLGVRSFNGRHFLGGRFIPKTLEEKYQLNLPEYPGSDQIVELKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Z5</accession>
    <name>A0ABQ8V8Z5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="64" mass="7626" checksum="5C3CC9CF5D7F1B5D" modified="2025-10-08" version="1">MKHKYDRETEDNKYEELITTPDRTSGWVAPTEIDEQIAYRPLIVMPTFPPRYPPNEVFQITKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9F2</accession>
    <name>A0ABQ8V9F2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_885968</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03085">
        <property type="entry name" value="PGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005737">
        <property type="entry name" value="PRK07564.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF2">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="11">
        <location>
            <begin position="16"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="12">
        <location>
            <begin position="205"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="315"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4481857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="565" mass="60904" checksum="C7C7856F6AFE6EE8" modified="2025-10-08" version="1">MSFPIKEIPTKPFDGQKPGTSGLRKRVKVFQQQHYTENFVQSIFDSIEPKGVTLVIGGDGRYFSPETVQTILKIGSANGVAKFIIGKDSILSTPAASNVIRKYKAYGGILLTASHNPGGPDNDFGIKYNVSNGGPAPENVTNKIYEKSKTIASYKVIEAPAVDLSKIGEASYGPSKVSIIDSVADYLTLLEEIFDFPLIKNFLSSHADEYRVLFDGLHGVTGPYASKILVDTLGLPDTSVQNCVPLPDFGGGHPDPNLTYAHTLVEAVERNNIAFGAASDGDGDRNMIYGKGAFVTPSDSVAIIADWADVIPYFKKGGVKGLARSMPTSKAIDLVAQKKGLEYFEVPTGWKFFGNLMDAGRLSICGEESFGTGSDHIREKDGLWAIMAWLNIIAAANAKSPNKLVGINDILKSHYEIYGRSYFSRYDYEEVPSEGANAMVAAINHALKNKSLDNTTHVSASSGGKFTVSGIYNFEYKDPIDHSISSNQGQVITFSDGSRVVFRLSGTGSQGATVRMYVERYVAPEAGAAALNGDTAEGLKGLIEVALEISQLKKFLGREKPTVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAX4</accession>
    <name>A0ABQ8VAX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_839067</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.20">
        <property type="entry name" value="DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041913">
        <property type="entry name" value="POLD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="369"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="436" mass="48016" checksum="C5F2D67FCFE5BA16" modified="2025-10-08" version="1">MGSQSAEDFLTKQIFIEGNIITYRSLSRQLSLHVNAAKNALATFHKKVRKEGECKASATYLVSGKVQLDTQEPDTMMTDVDMDEENIQYDDDGAEEAPLIEVVLVGEKDLELTKSKFSTIYSIHIYSLSPAPIIDMGLICGPNEIVRDIDNKKGTEMAAITGKIVGNVKEGKGKPYVQIPPPPPAATTSTILGPKSSVSVSTESNSITRNSTSTSEKPKRSDFFAKAKPKEVVKKEKSTKEESSKSKAKITAATSKISELEEKLSNVGREHKREFPPESKEDRIKASSTKGKAPSNHRTGHKRKSPDSETEIGSPSVTVKKNVIISDEEEDQSTPKVEHPQGRNKGKQAMRGSDEDVLKMMDVDDDQVIRVSHSRASPDLNKAVDSETEDIEMQDHTQHSKPTPQIKKKATKVKTIVPIGRNGWVRPCFKNSLTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB75</accession>
    <name>A0ABQ8VB75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_709100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4485120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="167" mass="19255" checksum="D57B470692884787" modified="2025-10-08" version="1" fragment="single">PIPSPPAKEYENWEAMRTIQENPDLFQIPKSINLDRFQALLTRHPNQPFVKSVIMGFRDGFWPAADTQFDKGYPVTWDNSWAPPPTDVERNFINSQRDIEYSKGRFSRTFGPDLLPGMYSTPVMAVPKPHSDDLRLVSNQSAGDFCQNSMVNRNWCKGQRMDTMKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBL9</accession>
    <name>A0ABQ8VBL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_922746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="114"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="114"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4478879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="382" mass="40175" checksum="26E030718F0C0291" modified="2025-10-08" version="1">MAPLSAALTDEGKRRSSMDKAKVSHLSRQLQLRLQYARLKVEHGWHKQNLNEVENLYFRRTNNRPRQQSGFGPTTQTSYLSTSNIHPLAPQTLSFKAHTFSKVSEPAQVTMTNHPVVPFSSSPATGPSVDSSPSSTTAELSESQSSSQGAINPSSLSPSTSNIGPALPSSVVSAMPSRAYTASTQETHQPIPSPSASAPAQTSTLHSPVIPLSARAMQKQRQTVKPIQLTSIAAAARSRSANTSSMPAYPASVSNPTRSVIPHFNQFTSTPVPLVDTMGRNVASLTYDSFWSSHNASVIANRPLSFRASVGPVGGKAGEFGAGIGPGIGSGVTAYPGAIHSGLENTLSVKSLARISSDLVTAPNYSGSTLGLSQSFQVPTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC09</accession>
    <name>A0ABQ8VC09_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_419689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="41917" checksum="C203CED20E4CC2EA" modified="2025-10-08" version="1">MGVSVVQGQFISLFCETCFYGMYTVLFMTLLVNYREKPATSRSVQIIRAITIFQYCMVTVHISLAFYQNYLAFTVFDDAEAEFNKLGAASYTLAQLAIEWTNCACADSILIWRVWILWNHSLYVVIVPIVLVIVSTTSGYLVCWSMNAVDSSASSDFGDLFGPAVEKWAILLAICVILTNIICTGMIAGRIWWHNRETQKAMGLNGMPHKYRRIFYGILESGALYLLAWIVAILLYLINTSAIIPMLDIISQLSGIVPALIVIIVSRSIDAATHYEEALTTINYRYNSRMQMGTSCTVDPELQASPKNSLEMIPVHLTNSYEPESPAREKRMVFAENASLEKIPKHTATTGTRTTVSGASSRTMGAGSRGESIVEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC43</accession>
    <name>A0ABQ8VC43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_904202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4481786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="26485" checksum="41000133C3AA88C9" modified="2025-10-08" version="1">MSLSEELYPIHPSDSETTHRRVKDYPPSQPRTFTSNSRRREIYSDTNQPSFFIVLCLLVLLGLRPKRLQAQLDSDDPKTWVDFREGLIRRWGTLGITSGLVLSAATTMLFSDRVLGASMVAALASLCATIVSITFGTALSFIFTDAPVQDFKALAARPIHMVFLLSIPNMFAMGSMVSLYISITIFAWTFDDGLASIFAKIGTVLGAAVMGGLFAYAIWLMQGLGMHTESHGANWTDGTDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC77</accession>
    <name>A0ABQ8VC77_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNL zinc finger-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_768047</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="6">
        <location>
            <begin position="102"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="54"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="194" mass="21119" checksum="0B380ED9F985D492" modified="2025-10-08" version="1">MLPSRLYRNVGIPPPLRSLLHPSPALPPSIRLQLRLRLGVFSNTAMNTLKAYSTATSSNSNDQSNTATSTETGDSEVISGAPPSSSSVTQTVTSQALPEKMAPRMSITFTCTVTDCGKRSTHEFAKSSYERGIVLVECPGCNNRHLIADHLGWFKESTEEGKLRTVEDLVRARGEKVRRGHVDMSGGVVEYTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDI8</accession>
    <name>A0ABQ8VDI8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Stress-associated endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_835086</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RAMP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010580">
        <property type="entry name" value="ER_stress-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06624">
        <property type="entry name" value="RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="65" mass="7463" checksum="7C21C2E77508A811" modified="2025-10-08" version="1">MPSEYEMRKRSEKFVQDAREGKKPTHMSRQEKLAKRSPIGSWALGVVLFVVLGGVLFELARLIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDK5</accession>
    <name>A0ABQ8VDK5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 10">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_389481</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 10"/>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07856">
        <property type="entry name" value="STKc_Sty1_Hog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038783">
        <property type="entry name" value="MAPK_Sty1/HOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4489193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="42479" checksum="2BFD48BAC8039DA2" modified="2025-10-08" version="1">MSFVKLSIFGTSFEVTTRYLDLQPVGMGAFGLVCSAKDQLTGSSVAIKKIMKPFSTPVLSKRTYRELKLLKHIQHENIISLSDVFISPLEDLYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVAVDIWSTGCIFAEMLEGKPLFPGKDHVDQFSIITQLLGTPPDDVIETIASENTLRFVQSLPKRERVPFSQKLRTNDPHALDLLEKMLVFDPRKRIDATQSLSHEYVAPYHDPTDEPEAAEKFDWSFNDADLPVDTWKVMMYSEILDFHQTGEAATSSVGLAEGPLAGADTVEAAQVPQPVAPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDP6</accession>
    <name>A0ABQ8VDP6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_393402</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046501538" evidence="6">
        <location>
            <begin position="23"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="344" mass="38193" checksum="0877B0906B65449C" modified="2025-10-08" version="1">MSTFNRISLLTIVLYCVALVVASSESPNLNSRSIHDIETRDTTTERPVAGFVMKVWPAVIGAALYGISGLLHWIHFFRVGQRYMLTLTIGMTCMTIGLLLRIAVSHSPYSLPLYIVEDMLVLLSPCAFLATDYILLSRLANSLGRDIADDCLLIPSRRITKIFVWSDVITFWVQAFGGGMSASTKTASIGTTVSMVGLVLQLVSFGLFTILLVTFGFRVQTKYPKAWDVQSPVLSVAGPFKTSTTTNWKILYYTMCFTCTGILTRSVFRIAEFAGGYNGYLATHEGYFFLLDALPLWIVMTMYCFFWPTRFINQHDANAASRYAPALVPLVESNKYGSQSTGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE17</accession>
    <name>A0ABQ8VE17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_834874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF39">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="125"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="24972" checksum="F6058F3C900744DD" modified="2025-10-08" version="1" fragment="single">MMIPVPRVRRVMKLEYLFFIVEDYIEGPTLAQVWSTYSLWQKIRVAFTLRSYIRQLRKLKAPRGAPPGPISNDGPRVCTSPLFGMLDLDQGPFASYADLASFFNEKAKLCYDYNNIPEDHPCRRQKFDDSEELVLSHQDLNPRNIIVGLDGTIWMIDWGWAGYFPPWFEYVAMKEKSLSEHYYQYWDLFIPFICGPHFEHEIWHLSMARGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE56</accession>
    <name>A0ABQ8VE56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation initiation inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_896041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00004">
        <property type="entry name" value="Rid family detoxifying hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="140" mass="14985" checksum="9F87254D61B8592E" modified="2025-10-08" version="1">MSTHPSLTPISTNNASGAIGPYSQAIKAGDLLFVSGCIPMDPKTGEIVQGIEEQTTQTLKNLIAVVNAGGSELGKVVKTTVFLKNMNDFVIVNGIYAAAFGSHKPARSTVEVARLPRDVLVDIECIARCVRWKRLTMSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VED9</accession>
    <name>A0ABQ8VED9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family group 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_382043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF3">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="875"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="908"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="949"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1001"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7928" evidence="4">
        <location>
            <begin position="45"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="677"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4489785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1063" mass="118358" checksum="816F18E297B62964" modified="2025-10-08" version="1">MASPNQVHFQPQARPVHPSHLNSASDAESYSPSHSLTILNNDYDAFDALLHNIYEKTLQDNWFKPAGDTDSTGVCLRVDPTSFRCFPYENPKLIPFEEGVRRLNVEVAVKIRSASVHAAVSRSPPTAREILIDSNTRIQILPDISALGDAEREQCAAFIRSDHTLVVWAFSVDQVIPLWAEFEEKLIKYIWRTRSTPRRDSNTPGFFDPTGSPVMHTGSLPDLASTVTSAAPSTIALPQYSSTRLSTAAGPFGMEDVDRSAADTIVVDFGFGAASEQDQEEKVVQPKKVSKKTKKSSFWSFLSWWKLQPPPPAQSEKDASTLEEGSDNGPEPRQLVLLGPFYAGCGAALTMYFAAAGISNLIEEWVLDGDTRRFGLVVVLPVVAAVSIFFCLQLIGNLSLVLGPVAQYHENSAYYSAQRPKPNAKVDGAARWSETVEQIVVRNSSENGTEGDLKEVERELQREVRVGGLPHITIQCPVYKESLELTIAPSVFSIKKAMQTYARQGGTSSIFICDDGLQIIPEEDKQKRLEFYANHNIGWVARPRHSSGPGGFKRAGKFKKASNMNYGLALSIAMEQQLAKLIGDASSANNPTSSSSEPRETSRPNTSASSPSTFSSQPHFESIESLEERALQLAIEQIYQESGTVKKVVDESGKETEEVVYHRPWAGGARSLRVGEIILIIDADTVVPEDCFRDAAREMGEEGGEEVAIIQHESDVMQVAHHYFENGITHFTRRINKCISYGCANGEVAPFVGHNAFLQWKAVQDASFIDPADGRRKMWSEANVSEDFDLALRLLLKGYTLRWATYSQGGFKEGVSLTVVDELARWQKYAYGCDEIIFNPLIKWWRHGPISKQLREFMQSAAPVHYKIGMSSYMFSYYGIAAATIGSILNYLLLGLGPDLDRFYLHSFEILLACVVVFPALGNLGFTMLEYRLGHRSIWSSAVENLRWVPFFLFFFGGLSIHLSTAILAHLFSYDMTWGSTGKEVEKSTFWIEVPRIIKNFKLSIIICLLLIAMMVVFTTDAVPFDWQIPGWNWALIIPLSLVVGCHLLLPIVLNPWLMKFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEG9</accession>
    <name>A0ABQ8VEG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_766732</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045831382" evidence="4">
        <location>
            <begin position="21"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="113"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4489815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="424" mass="45241" checksum="3655DB3D4DBB705E" modified="2025-10-08" version="1">MLRRVSILVLLGLSLHFLCAASPTKRHGVSIALPKRSSLTKLDGTFDHDKAVAQTVATQNKHRQNLINYMSNFGYLPEGMEIKPVATAPPRNQSRFNKRQTEALIDEDDDELWAGQISIGNPAQKFLVDIDTGSSDLWIPSSSCKSSVCSSKHKYNAGSSSTSKKLSGTFSIQYGDGSSVSGPIYDDTVTVAGITVTEQTLSGVTELSSDFQTDPTDGVFGFAYPKISNLKANTFFVNAFLQDAVPSNEFSLFLASSGSELFLGGTNTEKYSGVPEFHNVELSTGFWQISGASITYGSSTAVSGFETIIDSGTTIMYGPPAAVKKFYAKISGSQLFDATNGLYSFPCSTSSSISFSWGGKSFAISSKNFNLGQTDTGSSQCVGALAGLDLGLGSSTWLLGDSFMKNVYTVFSFEQNAVGFASLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEI3</accession>
    <name>A0ABQ8VEI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_766198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="30172" checksum="2FE35519A2C10A9A" modified="2025-10-08" version="1">MLDGPDDPDYKKAVSEMTESILQAGEAANWTRSERRHRRGDFPALARGISYGKGQREPMRLVGERQVMMDSLLNQDCFRRVAGFQSSAFATWYPKNHAEHLRLNAELHEKLPHLKRNFENSVYLGMTVNFGPSTWTHVHTDSKNDVRIPCAITTGGRFNHKAGGHLILWDFKLILEFPPGATILLPSALIRHSNLPVAAGETRISVTQYSAGGVRQWLEYGGRTEDEFRQQDPEGFARAWAKRRENYKEGMDLFCTLEQLKSRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFH3</accession>
    <name>A0ABQ8VFH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047481560" evidence="1">
        <location>
            <begin position="25"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="232" mass="23790" checksum="C5084994223BBC47" modified="2025-10-08" version="1">MHTTFGKFIASVCVVAGLVSHATADTWGPAFSLGPTKGAVIGTTTTFIPGTPPAEAETGLYLWIGISNGTSGLIQAGVDQDADNSYCGASATEWCLSASYFGIGGQFDGPYVAVSGSTEIGIAYTLSGQTWTQTVTVAGKVVSTLTSEDGPLIEGGWGTGTECQQNCKGTASVQQYLNSVIYLSEPDENFPNTLGVGAGVVHTPMETTDGGQTWTIASITLPVYTAPPGNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFI6</accession>
    <name>A0ABQ8VFI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_832364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="576" mass="64112" checksum="9CA3784F44DA66EA" modified="2025-10-08" version="1">MSMPNATAPSITRNVRQAIDTPGESVDPHSRENKSARLEDSTSAHVSPVITSPSIRRIPSRSNRTAPPSPLAGKGNPPRNLEDGEMSPDLDHDTPHLLDRDESPDPFRDTGRQGTDVSMEDDRLHWTPKSLVETRQTFRRGTGTDLGDPRGYNAAGLNTIRTSGRIAPRAQSNPPPPSFFLQPGFEFEKTKTPTSRDHNPHGPMPVLQPVEPDIQYMLDDATLNDGNFHRALFYPSDIVKGLLPTQLEAIEANPDVWVAISYFNGGETMHAILQDTTLRMKEWMQRADITYSSILTPFYPQPTQMGASSHGTKGNRGGRNTRNGPGTRGSHGTRGGRGGPGGSVNRENTKTSYEGLNTAFLKVNNRETVRLLTEWQTFAIDNLLTFHASPLLGEERPWVVCLIYSNEEGEDEETEKKILYTIKQGLWSDNRFIGLLAGKSAAPGSTMDKVLAFTNSLDLASNGYMIKKQGHNPWVWTLFAPPFATRGNLDMPTSRRQAIMDKAEKTVRSYISTKQYAWGETMVWGEQVECALCKITTHHTFQCPFPNVAGWQGPKEGLFNEIREARKRRSARNEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFT5</accession>
    <name>A0ABQ8VFT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxidase</fullName>
            <ecNumber evidence="12">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_337458</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="12">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00692">
        <property type="entry name" value="ligninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024589">
        <property type="entry name" value="Ligninase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11895">
        <property type="entry name" value="Peroxidase_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 12 15" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044949820" description="Peroxidase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="14">
        <location>
            <begin position="61"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="348"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4492473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="376" mass="39566" checksum="71F45969123595B1" modified="2025-10-08" version="1">MAFANIFPLVALALSAVKAAPTSQEAVCSDGTRVTNSICCDFIPLAQDLTETLFENQCGETAHEVLRLSFHDAIAISQSLGPSAGGGADGSMLIFPDVEPNFAANLGISDSVNDLAPFLASGKFPTITAGDMIQFGATVAVGLCPGAPQLEFRAGRPNATAPAVDGLIPEPQNTVDEILARFKDAANLDAEDIVSLLVSHTVARADHVDPTLDAAPFDSTPFTFDSQFFLETLLVGVGFPGTPNNTGEVSSPLPLTDGVNVGELRLQSDFELARDPRTACFWQSMINQEALMAARFKAAMAKMAVIGHNPNDLIDCSAVVPKPVPSLGIPATFPATKTKADVQQACPEPFPNLTTDRAPRETEIPHCPDNEATCTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFW4</accession>
    <name>A0ABQ8VFW4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_902903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051975">
        <property type="entry name" value="mtLSU_mL45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4492356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="331" mass="37640" checksum="AC7365AEF456701C" modified="2025-10-08" version="1">MNLAVVSRKISCLRHNTSLSLLSRVVPVDVHSIQARAAHAAATRKRRPANDSIDLDSYSEEAQLKFIRRAQIVGQNQGIDIWAHPVDTLDVAIPYATAPWSRSKFSSVKERLSQWLSNQKNKGKSLFSMMRLVSYDSLPGIDTQSMGFMGTLRMPLHLCTSSSTKSTSWIAPLRKILLENYISMQHALAKHDKEELSRLTQPPFYQEVEKLVKKGKANNYIWTLHREVSPAKIISIRSTEGHLGPVPPPNGNRLLVNALVRFETEQSLEVYDAQGNALHTPEPGAPKKSRRIPAEKRQLTEYYVFEKRMYYNTPWQIKERLYPKLGKQPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFX4</accession>
    <name>A0ABQ8VFX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_867226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431:SF7">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="27908" checksum="377137EC9A4809B3" modified="2025-10-08" version="1">MSAIRPVLVVAGVRAGGTGVATAAAFARKGYSLALISRGAEDLKALEEELKAAGNDATAFPVPSYSATSISSVFQSIHARYPSPQYAIRAALYNASHSIRKPFLDITLADFHAAQETIVEGSFAFAQEVIPIFKRNEIDVDTGKRGFIIFTGSTTSIRGNTTTSAAAPAKWGMRALSQSLAKEFGPYNIHVAHAVIDGVINTPFSRSRFHDPPNWVENEDIRLNAEDIAKAYVYLAEQPRSAWTWELDLRPAHEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG14</accession>
    <name>A0ABQ8VG14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_868526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="254" mass="29335" checksum="56A01EFC8930E1A8" modified="2025-10-08" version="1">MWSCETILPPIPNVDVGVTNHIMEDMVQANHILNMNVVCDTHIHIFEENMVPLFHIPNEDVGVTNYIMEDTVQANHILNMNVVCDTHIHIFEENMVPLFHIPNEDVGVTNHMMEDTVQANHILNMNVVCDTHIHIFEENMVPLFHIPNEDVGVTNHIMEDMVQANHILNMNVVCDTHIHIFEENMVPLFHIPNVDVGVTNHIMEDMVQADHILNMNVVCDTHIHIFEENMVPLFHIPNEDVVHDNHGPHPHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGA3</accession>
    <name>A0ABQ8VGA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_323650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4493281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="537" mass="61255" checksum="EBB4B2416C070EBF" modified="2025-10-08" version="1">MSQNTAPSTQTPEELDVVIVGAGYSGIHQLYHYRKQGYSVRILEAESDLGGAWWWTRYPGARVDSESPFYQLSIEEVWKDWVWTERFPCRDEVCEYYQHVERTLGIKKNIRFNSRVVSARFDDASSRWVITTKDGFVVHPRFFILAIGAASKPHTPPFADFQSFKGICVHTASWPEGLVTKGKRVAVIGTGASGVQVIQSIGPEVKHLTVFQRTPNYALAMQQQKLDKEIQQKSKRLFPDMFRRCRQTPNGYSFDRYPKSLHATTSEERLLFFEDLWTAGGWRFVTNNYMDIFSDQAANDEAYFFWRNKICERVHDPMMQEKLAPTSPPYPFGSKRPSLEINYYDVFNQPNVDLVDLTQCEISKFTPSGIQTADGVEHTFDIIVLATGFHTFTGPYTDLKVQAADGTDILEKWANGVYSHLGMTVHGFPNFFYMYGPQSPGACNGPTCSEVQSDWIVGCISHAMKHRFTRIEATREAEIEYRRLILELNARSLSRSTSEPTNFKGDLAQYGRLCAEVTEDGYRGFVFSSQVESRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGF9</accession>
    <name>A0ABQ8VGF9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Homeodomain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_326034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48472">
        <property type="entry name" value="TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48472:SF1">
        <property type="entry name" value="TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13384">
        <property type="entry name" value="HTH_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="19558" checksum="4788AD3388E2117A" modified="2025-10-08" version="1">MPNRRIPPEVKRCAINLYDRGVLDLSEILDRVGFSERTFYRVLACWRETGNVIPHKYGLTTGRPRAMLYDDIDYLLCLVRHKPDYFLDELLFLLEENRFISVHYSTIMRELSRCTISLKKLRRIAKERCPFKRAAYVAAIGQYTPDQLGFIAYLVLFKVNEFIWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGU0</accession>
    <name>A0ABQ8VGU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 9">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1 9">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_830036</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1 9"/>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4494159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="369" mass="41858" checksum="461FFB30377E118C" modified="2025-10-08" version="1">MSSRKSSSKPLPKFDIGEDYQLLYALGQGAYGTVAAGIHKPSGRQVAIKKILPFDHTLCCLRTLRELKLLKFFSESCVNENIITVLDIVKPSSLDAFKEIYFVQELMQTDLHRVIRTQHLTDDHCQYFVYQTLRALKTIHSADIVHRDLKPANLLLNANCDLKVCDFGLARSIKTTAPVGKGQGGMTEYVATRWYRAPEIMLSFKMYTKAVDLWAVGCILAELISGRPLFPGRDYSHQLDLVLDVIGTPTLDEFYAITSRRSREYIRSLPIRRKRSFASLFPHASSDAIDFLNKTLTFDPKKRMTVEEALEHPYVAAYHDADDEPAANSLSPDYFQFDLEKEQLSKDDLKKLLYDEVMSFQPVIGNTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHR8</accession>
    <name>A0ABQ8VHR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_315182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="128" mass="14174" checksum="5A4640A6CFEA30BF" modified="2025-10-08" version="1">MDPPYYILFSTQPANSSSLGHPTIQYHYADDSPLALLPQHTDEHVLLLEYDQTSLMPTVTSTSRTLAVTGIKVEEAPGAAVAEDRHNDRMYIIEATTVLAEDRTQLSGERPSAHAVIAQFKQRKVILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHZ6</accession>
    <name>A0ABQ8VHZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Pre-mRNA-splicing factor SYF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_866589</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">May be part of a spliceosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SYF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013260">
        <property type="entry name" value="mRNA_splic_SYF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264">
        <property type="entry name" value="GCIP-INTERACTING PROTEIN P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08231">
        <property type="entry name" value="SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4495254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="33566" checksum="565D098A7BBD5F70" modified="2025-10-08" version="1">MVSSTRFEEATTTIVEPTESLGQDPTEDTDMESAEIEAGSSKMTIEERKAKMDQLRKRLAASSRANRQSLIEESTKLKVTARDAARLERQRKLAETLREKADAEERGEDVNRAKNWEYTIEENDAWEKKLARKKRRADFEFHDDAHAARRRYKKDLDLIKPDLDAYNKQKEVAMGLAPGTLSNFNPKASPLSLQVSTSSLEQQLAADNLYRDANTLMYGDNKPSEDAIDRMVSKINKDIDKKGKFSRKRPNEDEGDITYINEHNRVFNKKIARYYDKYTTEIRASFERGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIH2</accession>
    <name>A0ABQ8VIH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_832541</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047009598" evidence="3">
        <location>
            <begin position="23"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4492430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="555" mass="61837" checksum="02C64D3549E1AE36" modified="2025-10-08" version="1">MESSNALAAIVLAFQSIPLAAGSYGGVTGLDSVARGICALIDQTTGPLLLYGLINLCYPDLCIPCIKPAFHLKWMGFHGSRVHICYPVLHFSYFDLKLRMARIGFIHTKGYETDIEGASASFRANWLDISNTVTRAGKFLVRGSSGGRKTLEQLEEGFNQSEEVVPFAPNSNHWIYPYLLGKQPREAGQMVALSRDCLIQTTALVIARFAILLASSMLVTLFHISVVLFLFEDTLTKVFLIIGDIGRWILVVGQLASVMTYSLDYKGVCSWASPKTYGARWSKREQIQCRNFVLHYIGKIYPADVVFRLAAWLWPKITAKTGGRWKDVLGEDEVFSSFHCFSENDFADNKSTLLRLFVAEKAPGESSIDFRDSYHIDFKVPTELIQSGFDSRLQPNPTQQKYNFRVMGPFCVCNILAPFVLIWRDGQSSNPTLTLIISSLFQIVTLVFNYKDLDDQSINCRFQNIPQPLVQGSHDTVPPSPFRKRRTGGSMGTRWSNVHHPNDFINAAIGVSSTSIATTGPSVVGAAMIALEEQDVTEGITDRKGKLRVKAREQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIT1</accession>
    <name>A0ABQ8VIT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Retinoic acid induced 16-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_762505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FHIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019384">
        <property type="entry name" value="FHIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045669">
        <property type="entry name" value="FHIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705:SF11">
        <property type="entry name" value="FHIP FAMILY PROTEIN CG3558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705">
        <property type="entry name" value="RAI16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19314">
        <property type="entry name" value="DUF5917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10257">
        <property type="entry name" value="RAI16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHF complex subunit HOOK-interacting protein C-terminal" evidence="3">
        <location>
            <begin position="744"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="512"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="898"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="998"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="915"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4495545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1067" mass="119747" checksum="C056BB1784B37BF7" modified="2025-10-08" version="1">MDYFQKFLRPGTQPAPKEVPDYTQEFTKSWNFVKNTLQHPDERQLARGIKSTDVPAHLQTMVNSLVTESTRIDEGTTGGCLEYLLKNDVLGTLVRLSEADRPFGIQAEVLRAVQNMVVLLDEQFLVHSAVHKAVLRLLRNCAGDDLHEQLDGRHKKVLGAAGNAVQTQPSEFEEDLVNLLCILCSRIRTFRELLMIFFHDKHWYRSEPLFSLEEEEEEEEEEDEEEESIANAVAEPPHRPSSPTPSQATVTSMPVYSVTTKKPEYEFLLFNYLLRFGHREGQIGEFARAGLLLLMDVAMSPGEPVHRLTGEETSSEATVDPITDAALALAEYILDGDFSEVLGAGLGAVYSMLPSKLEFRPPTNADRSQETGMVIGSMWLETEDEKEVLEVFRTKSWAMGVEDANSPDFKSRLDHFLKMLEFIQDVLRRNIIQEDVDASSLVGTAIVNSILDAVRRIFLENVLYPTILECSEADGSAVAVMSYIDIMIRTLQDGQLADLLVDFLISEDNEEVRPRPRPQSLMMLNNPPPQSSSAIADKETKSRRRKSSAMALLEIEAPETRKQSEYFTAMARFTLKDLILSNLRSASQPTSTAALQLLQAMLLQHPHLCTDKLLIVVADPLATAFPHPILISSKSGKDENEDEEETFMYPGIREEEKSPISSVPLFHQPDTTFSTHEREMDLYLALVSRVDPSHNSDPFSTGYDNYLRDALFSIQDQPAYQLDDIDGLDTEARQKDKHRINVNDPIISTILESLRRFFSNTPEHNIALTGVLSTLAIHPDRSLAGWLTFASNDSTPSNNDDIDAGLDANSDGDDRSIDYRIEEKLANNDSFLPASSMDEKSRPVVHAIFHGLVAQLERYRRSVNNFDQFLLERRQGLLFSENLSDALTLAIEINENTPRLPPLSDVVQHSKPKPRQSTSSSLVSLFTPKRNKSKSTMAPLPSTPPKKKDTNKTFSESPFAPHYQKTGAIVVEPFVAPVPASSPWTPVKTPRKWNPDEEDVFGAGWSERTPAHTTQDDSDEEESEKKTTTVTLSRLLDNVVILEESIKELVAIIHARRSLGIDSVRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ95</accession>
    <name>A0ABQ8VJ95_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Phosphatidylethanolamine N-methyltransferase</fullName>
            <shortName evidence="13">PE methyltransferase</shortName>
            <shortName evidence="13 14">PEAMT</shortName>
            <shortName evidence="13">PEMT</shortName>
            <ecNumber evidence="13 14">2.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_795877</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64573"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="2.1.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="13 14">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13 14">Endoplasmic reticulum membrane</location>
            <topology evidence="13 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13 14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.17" evidence="13 14"/>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03217">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016219">
        <property type="entry name" value="Phosphatid-EA_MeTrfase_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138:SF0">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000383">
        <property type="entry name" value="PEAMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51598">
        <property type="entry name" value="SAM_CHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 13 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11 13 14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 13 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="561"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13 14">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="328"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="960"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="328"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="363"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="977"/>
            <end position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4491041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1051" mass="118950" checksum="22427D291D80E091" modified="2025-10-08" version="1">MATSNSQSFLRQRAPPATNDTHVRNEIEEPPADNRTKREVVWGKTPSGEVFRVPTTHDVLTLFNPAYPKSHFDILSLTLLGSQIVLYFIFPRHISQIFFFLYFAFWRAAYDAGLGWVLTKQSKRKWIEKQVQKFGWMDEKRRPEVRNWVRAQLAGKMGKDYSFDELPMEYNTWLLFRQAVDIILLNDFVAYCMFAFASFRVPEGLSNFVHVMRWIGGLALIGFNLWVKTEAHAVVKDYGWYWGDCFFQRGALVFDGVFELAPHPMYSVGYAGYYGLSLISGSYGVLFVSLAAHAAQFAFLVLFENPHIERLYGQRKAIAKRTPLVSSLKSTNKPVPSTSGIEISEVEESDTELTTPSATEGETATDTDLETETETEIEEKENHVGIVLKTNTKLRSPVRNGSGRMSPKSPRARKSSNHRQQGSVASSLSTTSTGDSTFKTRKSVSQHDLLNKYFRRDMVIFRNLDVLRAPDALLVILVAYVALFTLLPSSVFASHSSLVAVHFIHALSWCLFHVFGLGFLLRAQSESKFLVKHYMKNYHYTFGNEEGAKGAIVEAFANFKAIYNASLCMTYVSFIGLVWRTYSIPSNWTVGVELLRHTLGALLVGLHVWATIESYEVLGVFGWFFGDFFMEEFPSHLEYSGIYRYLNNPEMMGGAAWFGLGLISGSKLVFSLAVIKHLGHWWFVSSVENPHMTKFYGDSLRKEAGFIKVIKNVASKNARLLESRAGKHAPELKRVAKEVKGTFDKVFEETADAVEEFLAKSRPKISGVVFDTKVLLQQSREKLVITRVVSDMSSYDTSKYRATILPSYDGTLRFHLGEPIKIRWQAPHMHSRKDWIGLYRVGANKSCLITKTSSMGMWVPVHDEEWDGDIPLGRDRPDVPVKDSESGVVTFKDNNLPWITGRYEIRYHHDGKYNVMCMDGPIEIYVETPAELNFSAVRQTLMRIVPLCLDSDPSLIPLSCKDDKTPTLEQGPSISRVELDPPERAADFDSQSDMEERGPDPDDFSFWSELQAKRICSAIKEAFGVEYAPEVVLGDANLSALANRILLSKQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJF4</accession>
    <name>A0ABQ8VJF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_828441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="904"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="790"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1020" mass="107681" checksum="7B8CCF3978BFF177" modified="2025-10-08" version="1">MSSFQTTEILFNSPALHSLKRDQLVKLCKIHSVKASGKNVELIERLKRVAEDLPKGSLSIGSGNHDTDNGDMEIDEAVDNGGDNKENYADRKIGSTTVMVNPPRPSEQWEVMESIAECENEDSGSRNGTLRSIASNREFGTGGSKSSTISSIKALASSLGLKRSTSAKSVVANSLSTQPPVVPPISSESFQNAHASGTRGDRFPPATDDELSKHAIPYTRLPVPSPNQIPQTDHFSDFSHFGANPPTPSTLSKFDFNNKEDTAPLPGHVLRPGAPAPNNARLSLGDARFSLGYGLATPRKSASGATTTIRLVSSSSMIGITNFPGPSTSTLDIENSSTPHLKPWNTAFDLVLGSPSGPGQGENVKIYPDLPMEDVPVSSTTVEPSQTLSDGFPHLSGAKSQAFVFGSPLPQHRVSNVQFQTAAASVLEEMNRRLLADGVEAVGPSLVSNLRPGAGGHLTPGTQKVYTDRQIKPLRKSFGAHAVQKEIQQKFEKAHQDQFDGMESIAGYLDRKNNSSLVGKAPVGTSLSIESVQVGKKRKSSAIDDGRQAPAKRPSTRVISNSRRTVPGGFGDEDEDEEAPVGKKPRVEFSGKDDTGAKEVVQSALEKSEKEREAIRRKLEMNRARRRSSTANGRASMGRGRVSVGRNSKLLPKQAASKSRFGFLSNAAKSIVKGVWGGGKKTPAVVPPKPVFKAPSSTTSTAKPVPSTGVTEAKAKVTPSGTQRKFSATDSGTSPRNRDVSNVGTMNSLGSVATAIHSSRSRSPLPSFAAPTKSSSVRSSATGTTSTRNSSIAVSSRVSRTSTTSATSSRVSSLGVRGTLDPNRVSSTTSSRLLAPTASSLAKVASLNKLKSDALNVPAETPFASSPSSSKIFSKPLVVPKGSGLPSPVRSGRSQTVTREITVKQRSLSGRKPRISRSKVIAKLASQRNPSGRSEPSASTDYTGPSAVGLAAKRSSLGVGVHKAPRKSMGAARRSHIGVSGARSSEASVLLSAKKRARQSEYARRKSRAATGAEPMKVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKC7</accession>
    <name>A0ABQ8VKC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_298292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="39053" checksum="3C2EB883DE4778A9" modified="2025-10-08" version="1">MSRKVLELYLKNRGKSVPKPEFQGQPLPDASVGHFRSDTSRSTYELCRRWETAAQQYEDKKLMQARVLGYMLYYSPTDAARAAITRAILSCNDNDEQLSELAELYTFFFVRCFRKFKGRTSTTQSHPSPDSFDVMKNVIFNGFRDPFTGKYDYLAEQFDAIDPPELLLEFGCASLQVVHIAPDSTCFRLEGVKTDYAASVTAILQQFGYDFEKFKGAKVHSLYNLITMSLDMHYAFDQLRIYLEEIGTNTYRVKGFKQTQMVPGHDIKFSTDDPEFYPVPDRELIALHAMCAKVAHMSGAGAYIEDLDRDVEDLGVLASNGGSADVLSHALAVVADFSYPHYVAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKJ5</accession>
    <name>A0ABQ8VKJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA ligase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_765356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="T4-Rnl1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015966">
        <property type="entry name" value="tRNA_lig_kin_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004:SF1">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08303">
        <property type="entry name" value="tRNA_lig_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T4 RNA ligase 1-like N-terminal" evidence="2">
        <location>
            <begin position="64"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase kinase" evidence="1">
        <location>
            <begin position="421"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="58773" checksum="C3C478D1F0A95FAB" modified="2025-10-08" version="1">MPHPATKSEDSDLIDALLKLSSKNPKLVKLTVYDAPADPTLGVRSWKMNEYKYYDIPSPFPTLARGLFTLQVGRDPNSHRIVIRGYDKFFNIGEVPWTTWSSLKMHTAAPYTLSLKSNGCIIFIGALTPEKLVITSKHSLGPIGQSEKSHAEAGEGWLKRYLKEKGRTEAELAKTLWDNNWTAIAELCDDSFEEHVLGYPPHLTGLHLHGLNTCTKEFSTLPHSTIDEFASEWGFIKTESIVFNSIEEVQKFTDEVSKTQHWNGQAIEGFVVRTHVTTPPSGNENHRGKTPYAPGSTFFFKVKFDEPYLMYRDWREVTKTILSVHKKGARVAKTLENTVPRSKMKRPETRVYVRWVIGEILRDPSLFKEYTKGKGIIATRERFLQWLEAEKGKKGISSDGENFGSETEQKAQMKPEFGKTVIVPIAIPGCGKTTVAVALTHIFGFGHTQSDDVHVQKSAPVFLKNVQNLLKSHDVVIADKNNHLRQHRTQLRELTQKMIPPVRLLALNWSLASYPQSTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKM4</accession>
    <name>A0ABQ8VKM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1446-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_824058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF1">
        <property type="entry name" value="DUF1446 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="11"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="543"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="663" mass="72940" checksum="B0BA948D9C16B9AF" modified="2025-10-08" version="1">MGDTTSTRRPIRIGNSSGAIGDGPDQLYRLATEGPIDAIFSDYLAEVNIPWRALEMIDNPELGYEQSPLIQLQWENAAEEIVNRGIKWVHDGGALNPRGLYEEIKKILDAKGLLGQTKLAWVEGDNVLDTVKPNLADIHGAAKIYSHLDIPGQTLNDAFKDGDVGQILSANAYVGLRGILAALEDGAQIIVCGRVCDASPVMALGAWWHGWSLTDWDQLAGSLVAGHITECGPYTTGGNFCGFCNLFSDPGSPEAKFYDLGYPIVELADDGSCIITQHPGSNGGVTVDTVTAQLVYEIQGPKYLNPDVVANLENVRVETMPGEKNKVRVWGITGSPPPPTTKLAVCSLGGYQAEMTLFAVGLNIKEKYESWKMQVMRKTDPSKFSKIAIDLYGYGFHSLPTSETSVNTGPGSQLRYNDPQSQKDCTAMIRHFVQAPTKDVISDFMNLFLTMGMAGYPGLCRSLDFRDGVPKPFIKYFPAIISQQDVTMRVHLDNVGKSDEGRTIDISPIQEEHTELFNGQRSYDPDDKLSWANFGPTRRVPFGTLVLARSGDKGGNANVGFWVRNADYEAWPWLRSLLTIEKLRELLGKDAYPPHDQFQSRPYQITRFEMPHIHAVHFVILGILEDGVSSSSLVDPLGKSVGEYLRAREVDVPLKFLLGRELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKS7</accession>
    <name>A0ABQ8VKS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_826738</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="9">
        <location>
            <begin position="88"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4496496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="251" mass="26819" checksum="FB8677B2DAFB818B" modified="2025-10-08" version="1">MSSESFEQISQSSLKQYQIELIDKAMSCGALKFGSFTLKSGRISPYFFNAGLLSTGPILAVLSEAFAATIVAAQRPTSSGNIPIPPFDVLFGPAYKGIAFAATTALILHTHHSNSPNSISTSSEAGIGFTYNRKEIKAHGEGGSLVGSSVSGKKVVILDDVMTAGTAVREAIDIVKKEGGEVVGVIQLLDREEVGQDGVSSTVDEVEGIIGKGRVRSILRMRDLIAWLESKGMGRELEDMNEYRNKYGLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKT4</accession>
    <name>A0ABQ8VKT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_727048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46155">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR/LIPID-TRANSFER PROTEIN/SEED STORAGE 2S ALBUMIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46155:SF1">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR_LIPID-TRANSFER PROTEIN_SEED STORAGE 2S ALBUMIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="160" mass="18042" checksum="3CF0553A6E5EA50C" modified="2025-10-08" version="1" fragment="single">ETPSQSPSQMPLEETPHESRFETSHRAPHESRFETPHESRFETPHGTRFKTPQGTPLETPRGTHFETPHGMCFETPHGTCFETPQGTPLETPREMCFETPHGTPHGTPHETPLETPFETPHETPRGTPHGTPFETPHQTPHQTLSETPHKIPYELPSPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLB7</accession>
    <name>A0ABQ8VLB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD-repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_760286</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="7">
        <location>
            <begin position="31"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="142"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="227"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="416"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="458"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="546" mass="59847" checksum="891AB08B6B8E38CF" modified="2025-10-08" version="1">MATLLPPPKRQKVYHGVPEPEPEAPKPTRNILVQFVSEDDGSVLAPAVNLPADVSREGLEVLVNRLTKSDEPVPFSFHVDCPENVNAAPGPTRIVISKSIQSDILNHPIHADSFTEEDVFVVRCSPQSVFRVRPATRCSASLSGHSSPILCASFSPTGALLATGSGDATARLWDLNTETPSHTLVGHKGWVLCVEWEAMERLLATGGHDGHVRLWDPKAGKPVGDAMKGHTKWVTSLCWEPIHLNSKSPRIASSSKDGTVRVWSTLTRKVEYTLGGHIASVNVVKWGGGGTSGFGLKRGVLYTASSDRTVRVWDADCGRQLHVLKDHAHWVTTLTLNTDFVLRTGPFDHTGKRPANDEEAQHLALKRYTDVLATTPELLVTGSDDHTLFLWSLFPSSVPSSDIAVSQGKLKPITRLTGHQRQISHVAFSPDGRWAASSSWDSSIRLWEGRTGKYVATLRGHVGAVYRLAWSADGRMLVSASKDATVKIWDLKTYKLKVDLSGHTDEVYCVDFVADKVVSGGRDKHLKMLAFFHLTVHRKFIVCISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLN5</accession>
    <name>A0ABQ8VLN5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_760912</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="444"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="765"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="802"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4496811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="964" mass="106902" checksum="E5B3D7D743575531" modified="2025-10-08" version="1">MSELSSPASRRSALPPSSAPIPTQSQSTNGRSTPRRRTDVLALGDEAGVEGGDEEEPSAARKRRRPRTQQPGDVPLVQDTVGERVTETFETFLRTFTEDVALASTPMSDGDLPDGSEGELVYVEQIHTMRAYELTTLYVDYGHILAKDDVLATAIQTQYYRFLPYLRRALHNLVAEFEPEYLKINPTAATTDSANLQSREFNIAFYHLPLVSGIRELRTHKIGTLMSISGTVTRTSEVRPELLFGSFICEVCKGLVNDIEQQFKYTEPALCPNPTCGNRSAWQLQIETSTFTDWQKVRIQENPSEIPTGSMPRSLDVILRSELVERAKAGDKCVFTGTFIVVPDVSQLGLPGGENAQLQREANRGNSTSAGVGGGVTGLKSLGVRDLQYKTAFLACMVHDSDTMGGTNIRGEEEVGEESGQSFIQSLTEPEFDELKAMIDSDNIYQRLVESIAPTVYGHEIVKKGLLLQLMSGVHKQTGEGMHLRGDINICIVGDPSTSKSQFLKYICSFLPRAIYTSGKASSAAGLTAAVVKDEETGDFTIEAGALMLADNGICAIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPIGGRYDRKKTLRANLQMSAPIMSRFDLFFVVLDECNEKTDRNIAEHIVNVHRYQDEAINPEFSTETLQRYIRYARTFNPKLTPEAADVLVEKYRMLRQDDASGAGRNSYRITVRQLESMIRLSEAIARTNCTSEITPAYVREAYTLLRQSIIHVEQDDVDFDEEELDGKRERLAAQDPSTEAAEESQDVEMSGVDQSEESQQIDGGETSTVVNQTSSTAVAGQSSHADQVQQAAAATSSKRRMVISHDKYITLKSLIVYHLSEVERETLQGLDRDDLIDWYLETKEEEMQDIEDIEYEKELITKMLRKLVKENYLIEIRGDVQDSLPESGFSATEGEDVRVYYMVHPSVDADESSEFPSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMX6</accession>
    <name>A0ABQ8VMX6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_184408</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046183036" description="Transmembrane protein" evidence="3">
        <location>
            <begin position="33"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="44458" checksum="7E97CF370307E93D" modified="2025-10-08" version="1">MTRQSIMKSKFWQRCLCAFFLLITTCTERMEAVEASNLGQGMCFIGASRFLAFRFFCLSWSQTTCSLAIYTCISFYAISKIFIYAFLSEKVRESQIHTAHLREQFRQVYIVWTGGNQNSRLKARVYRVCAVVLLGYVVVGTLTVIGRDSTIRGDGVCIIGLKSYATISLIVYDMSLNIFLTAMFLWPLWLSHPMSPKLRSITKRTLYGASTSLVSSMINIAILFLLGGNELGWVCLSSCVADVTVNSLALFWLSSGSSWSGDVVRDRFSLPAMDMSALTFVHIESATRPTLLGQPSTIIASESTQDSHQPHVPMIPEAYFDYIPSEHRTLRNDTEEKTEHWVCTSNPVSLERSYSKSYSDMSGSSTVPENCHAQPSKASSETAGQTATMEEEKDICDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN23</accession>
    <name>A0ABQ8VN23_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IQ domain-containing protein-containing RasGAP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_214651</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21206">
        <property type="entry name" value="CH_IQGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="445"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="1167"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1823" mass="205935" checksum="63871AC443A979C8" modified="2025-10-08" version="1">MQRSDSLSSSSSNPSSSRPNSSSSGPFAYQTRLLERTSSSSKGSLSRTNSQSSNNILTNNTGSSTSSATRRWTPGHRVANSLDAVRGKWEERVRENAIDESPSISHTPTRLTTFAKLQNSVDSSPVHSTSSPLERTPTYLKRYTTSSVPSPIIATPLSPNSTGVTVEADSPSPTMSSQRIHLPSYDHVSRSAGAIGRPTSPTLPQASPARRNTVDFSSLKRINPSRNDVQPPSTPSSPSIFDQSPSVISTPTSVQRRPTSLYSRPSVSSDRDRLQHQSTGSTSYNPLSPTSGNSITAPPPSSNVMFPSTYKSSYMQNKSRYGNTLSAGGRRFGKHLPRIASGDTEDHVEEKKEREVEREVEKEPPPSRVERRAMRRDGNFDTTPRRATTLEAPVADSDAVIGIPGRMRLSRNKAFNAPAPLPSARLARGLWADTQRHLIQAYEYLCHVGEAQQWVEGCLDQELGFGVVEMEEGLRNGVVLAKLVRVFQGEGVVRRIYEAPKLDFRHSDNINYFFIFVRHVGLPECFIFELTDLYEKKNLPKVIYCIHALSHLLARRGLAERIGNLLGQLQFSDDQLQATQKGLTASGVTMPNFGNVGRELAKEINEEPEVEVETDDERRDRLLLENEGSILGLQSVARGYLARQALKALHGHLQLSGANIVKVQSQCRAAMTRRHMLQQRNARNDLHPWTVALQARIRGALSRRRWYSHLSRIADSSVSVVKLQAQLRGVLLRRRYNRLRGALRSSKRVFVNLQSIARAKLTRQTHNELARTFSHPEVLSSIAAFQAQGRAVLFRHKFSQRAALMYRLSPCYIALQAHCRGVLVRRQMRKQMAKLEDVSQTVVRIQAAVRTYLARKRLLVLIRGLRKATPLVVGFQARARAGLARQKHENLGKALSEVKTIKAVHGMQSLARAALARNRHREISRKLDFVAPDVVGLQAAVRGALSRDLYYRWRDHLHNNEHVATVLQAMLRGLAQRKKFRAKMDYYRANLSKVVKIQSLFRAKETREQYRQLTMGKNVTVGTIKNFVHLLDDSETDFQEELKVERLRKKVVENIRENQALESDVTDLDVKIALVVQNVKSFEDVLKARRGLGADSAAAHAARSHLLAAHGDPFAGPNTLDQTARRKLELYQQLFYHLQTHSEYLSKLFVRLSRDDTPEKDRRFTEAAVLTLYGFGQDRREDFLLLKLFQSSIYNEVSAARSIQDIIDGHPMYINIAVHYVRPKQIAYARDTFQTLIRQIVEDDDLDFEVDPTVVHRARIELEEMRAGIPSPQPKDVSFRQALDDPATRPIFIRHLQALQLWTDRFVAAIIQSTKKMPFSMRYLARETLACVRERFPDAPEEAYAACVGRLVYYRYINPAIIAPETFDIVSKTVDISSRKNLAQISRVLTQITGGAVFDDHSPNMMPINEFVSRAISQISSWMLEVANVPDAETTFHAHEFLDATVPPKPIYISPNEIYSMHALIVQHLSEVAPAPDDAIRAILTELNGVPNFGNEELKDARDRTITLELTNRFANVEDPLAEEKTLWVQAKRGVLAILRVQPTQDLLGALLRPVTEEDESVWEDILDAEIANEARQIPRRQASAIGADAAYRLEDIRLLNFAAVKAMAIQHLLKLESLQKISRDDGFQGILNAIAGDVRSKHRKRLQRQQEMESMNEALQHLAERKKYFQEQIDSYHNYVDAAMNTMQRGKSGKRRFVLPFTKQYFHLRDLQKAGQSPQFGSYLYTAKYLYDKGILLSIDQYSPRQFDKLNITMSSNTAGIFTITLESSAFGVSSRVASEDVRMEELLQAKYEQRSFISLFDGRAKFNFELFLYQINKKFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNC8</accession>
    <name>A0ABQ8VNC8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_820013</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF26">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="905" mass="99754" checksum="ED957C2F516B6CFC" modified="2025-10-08" version="1">MQTNTKSGSETPPGNKSKSTSSPPPLPSVPPAAPPQNPKPSSSTKKSRQRKPSADVQPSATEPPPQPAVAQGPVLQPYPGPPYYMNHPYPINGPPYQQPQHPGYPPPPQSTSTPGAPPPPHYAYPMAASPHPYYTYQYPPPQPMMVYGAPPPPQPPPPAEIAQANSPPPQTPTTSSSGAKRKRKSAKEKAASDDEAASGQDGSRTQGQSQIDPKKRTKTQRACDSCRTRKIRCDVLIDSDPPVCQHCRQYQFDCTFFLPITETRFKKKKLETEETDKDKSFSTRASAAHDPRREIGVLGVTSPTHLLHSQATISSRVYQGYDARYNHTFEVSKTGDGLISVQKPSNEEQQTKPVEYRVERNLIEQLINAYFTDVAPLLPVVTQVEFLAHSSPPPILLYSMCLVAAARRDVPQQVFDSIRYTVNSIIKAEDVLSTASIVNVQALLILCMTGDCHSPFVPTALSALWIRLGTAIRMVIVSIQPIRIVSHGNYKAQDLGLHRCESVQQNVELRRRLWGACLISDRWYRFFSNYGHPYMIDIQDCDARLPSSGDQNDLYMDELVRLSIILGRVQKAIYTPAGLMVATDALLNQLLTDLEAWKKNLPEQLRFTGPESSRAAGLLYLLYVCVSMMFWRVFMRISYTCPEHLKFGLTVEQWSALVTSTGQAIDWLDANEKLYDVWLLVAYAAASCGFVQYHTYVRRKDAEAEAKLRKLRDCVRRWEKSISPDHMSARRKTAEIMALLYEAIQTPVMPLEAPVLNPTGGVKGRQQAVLDYKPDPTRPGTGVFVAHGQIDSDPPMTTALAASTQSTTSSGPIVNFTPLTGAAIGSGVSNVNPAMNVQAGTSDRIINTLDTPATVENLAEFAVTDTGFLEGMPNLMFDWGQWDSFFSRFNGASDGSVQTHPSSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP78</accession>
    <name>A0ABQ8VP78_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_819628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="22596" checksum="65F954068F204A26" modified="2025-10-08" version="1">MFDDELSSVSSTSSASSPSKRRFRLPPLTRRDPVGIDPDELIGKKLIRISRSSVHPSLTLDFDDHTSAQVLVDGYSPRWKGIPKALEMDEAFQRLTNTVFVGLDTLEIVDCAMIKLCDKAFQRKQNDDHDSTMWDQEHAAIAFKFSGENPHWHCVWAVLAEYDEDRTCTFRSFEDVFLNYLQRSPRKQSRIDKLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPP9</accession>
    <name>A0ABQ8VPP9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate-binding module family 12 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_818918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12214">
        <property type="entry name" value="ChiA1_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.10.20">
        <property type="entry name" value="Carbohydrate-binding module superfamily 5/12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31649">
        <property type="entry name" value="AGAP009604-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31649:SF1">
        <property type="entry name" value="FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02839">
        <property type="entry name" value="CBM_5_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00696">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="Carbohydrate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-3" evidence="2">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="315" mass="35461" checksum="B0A05061F88AA22E" modified="2025-10-08" version="1">MSAPYWEPGTAYKPGDVVQYEGHRYKIVIPHTSQSDWAPTVTPNLWGRLSDEDQGQWGGYQEKHQQPAAYQPAPEFHPPAPEGQKVDIQPEERQKHWYDLDDHRKKELEIGGGLLGAIGAAAAGYYVYKHHEKSEEDKKADSWALQNWLHDAEARLNEYKKYGPRSPAQWVLNRGKNIPPNAIVVGPEHDWMLWICRAYVDGTIQVGKASNVFEKGAVVGYDNKEIQLDTYEILVGDMHGLQWVPASGRLNVENLGLRPVEGGRDKDGTPLYIAQGPHKDAVHPGIASSKLDGAYIPYGGKQVHINEYRVLCYNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQC6</accession>
    <name>A0ABQ8VQC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_979132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="454" mass="50908" checksum="C3A50BD8434319B3" modified="2025-10-08" version="1">MAFLETAERMKDQSMKPQAGDLRNVFSDCSDIHGAHPSRTSFSSYDTHYFTKFNDHDGLERVLRLDKDSGIRVIPVSASPVLAERYQSVNSRGSGTPRPKEHPLNNLQNIPIVDASRVRPYSHIPDAVLTPSTNLVHAPDHNRTEIDAPKFNNHDDTNPPIWMNALNSSSLLSPIVINKQHSYPHSSEKPKTATVSPLTYIHSAKALESLTLPCIPLTTHIRLCLCGELFSYNLSNLQSDPREIIELLKSTGSERGNWMTVGACYRRQCNPHAAIAVIQSMVEVMARYGVSENELKPAFLLLAGCESDLSKLTRNEGRITLEHQQKSQRWLQKVYGAMKSNSDSIRVDAPSSNPKLPAHPPSPPGSDEHLRREIQSLRDRLRHQALAVEASGPSIMILGSDHRKLQSSNPGLLSDVRSAKRKLEGSYNSERDTRRRIEREIKNMKAGRDKTFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQJ8</accession>
    <name>A0ABQ8VQJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_121148</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="10">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4498665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="114" mass="12743" checksum="9CF91062A4043136" modified="2025-10-08" version="1">MASAYYEFYRGSSIGMALTDSLDELITSGSITPQLAMKVLQQFDKSLADTMVRQVKNKTMLKGHLHTYRLCDDVWTFIVKDASFKLDNTELVNASKIKIIACKNGEAIESSGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSE6</accession>
    <name>A0ABQ8VSE6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">AtMMH-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_893591</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08972">
        <property type="entry name" value="PF_Nei_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="entry name" value="MutM-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="FPG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="H2TH_FPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993:SF9">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="N-terminal domain of MutM-like DNA repair proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formamidopyrimidine-DNA glycosylase catalytic" evidence="11">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="327" mass="36765" checksum="22F33CF1F1CF1636" modified="2025-10-08" version="1">MPELPEVERAVKQIKRLALNKTIQKVETTEDNIVFSGITHEEFANEITGRKITGVKRYGKSFYLELDGQGKLPVLHFGMTGMLQVKGEKPMYYKENPKSASTDWPSRFMKFILHMRDECTQATAEIAFMDARRLGKIRLRATPDKEAPISELGFDPILCMPSLEVFEPLVMKRSCPIKALLLDQSFSAGVGNWVADEILYHSRIHPEQRCNTLTTTQIGNLHQFTKFVCETAVSVDADATKFPEDWLFKHRWGKGKKTKADPLKLVSGDFATIKWVTVGGRTSAYVAELQQLTSHEAPGGSESDLSVLTDSDPEVSQPSSKKRVRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT97</accession>
    <name>A0ABQ8VT97_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">D-3-phosphoglycerate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_754455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12176">
        <property type="entry name" value="PGDH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050857">
        <property type="entry name" value="D-2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008759">
        <property type="entry name" value="PRK11790.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="7">
        <location>
            <begin position="57"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="8">
        <location>
            <begin position="162"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="50414" checksum="43F7E06C23D95F42" modified="2025-10-08" version="1">MSSPIQIPGAARIVAASVSPTATNIHDRFASVHRQDSLNVRQPRVLHPVENEGLRLLILENISMEAVSAFKAQGLHVDHHTKAMSEDELLKKIGSYHGIGIRSKTKITEKVIKAATKLLVIGCFCIGTNQVDLTAAASAGIPVFNSPFSNSRSVAELVMSELVVLSRQLFERSFELRQGLWNKQSKGCWEVRGKTLGIIGYGHIGSQLSVLAEAFGMRVIFYDVVNLMPLGSARQLESLDALLSDADFVTLHVPELPETINMISRDQLALMKKGAYLINNARGKVVDIPALIDSLKSGHLAGAALDVFPSEPGSNGSPFDDQVNSWASTLRSLPNVILTPHIGGSTEEAQRMIGQEVSQALLRYVGLGSTIGAVNFPEVDLRAITAEEGDHVRVCYVHKNQPGVLKLVNETFAPYNVEKQYSDSKGEVAYLMADIANVSPMDVTRLQESIRRTDANILTRFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTD3</accession>
    <name>A0ABQ8VTD3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_863965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="467"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="688" mass="77108" checksum="617D5D96AB0D137E" modified="2025-10-08" version="1">MSAWGNNNADWNFDMPSLVEPEHFGGGDGGNIPPPRGARFEASQGLSMGAFPGIVDSGWGVRPGTPHPRQQVPPGWDYQAPPPPHTAPGAFYHPNLPHPSQMPAHYNNMPSPWAHAHGQGQSTFTPREDGFSSLAWRPPDYDMDRASYVEYGGGAYANDYGRGPPPGSAPPRTGLGLGFGAGGGSENPYTDQPMNSGGYFANAGRHHRSHSRNHSRSRQRQEPREDAYGWGAEPAGAWDEDQLDEEDEEEEGMRRARADLMRSMDRGHENATSGSADWDLIDSFSGMGIQDGQRDRSRHRGRSRSRSRHPDRHRRKSAMKRSYSNDMAPQASTNFNIEPHRSRERMDRLAWPSQNSPYGSSNRLIENQIYGPQDRVRRPRDWRAEYSVKPNIFTRFSPRQWHSSDVIEMNDPVKRVPNSLLHRTSSSHPPTFIDLRIPIQTQMQLHAEQRTHFGYGSGGIFPYLNRPPNSIDFAQMACEPASPHMRLYHPRLPWYIDLMSTSAIAASRADAGPSTPGFGVGYGVIGLTVWEVIEGVWRELQKQITSRDFYNEEMGTVMTGGRTRSTSLTSHSPFSSHMPLTPLSSNSALPLSPGHGYDMYGQPQLQPTQTARDLVSMAFRSRCKFVGQELFGDSKRAKLDFGHFGQGEAREMSKGVRRVDWLGMEEEWVWTGIVRKSSGMWEIKTRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU54</accession>
    <name>A0ABQ8VU54_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_812482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27077" checksum="643FAAE2C9162336" modified="2025-10-08" version="1">MDANDTQDIQALLEQLQHSQAWKDAVASSYPDGSPQDISDTPQSNSAPQAVSVAALLSQLQTEPHPNVVDTSQNHHLAAFQNDSSESSFSMTLPASNNSVHRPDDHRYLTFQQALPLIARKSASPSFAEALKAMKQEQEILEIKLSDERKAILSKYETRVNVAKTKASMIGSGISRHEANMLVDAFEKELKRFDVERVLPAWDGLVLQQQEALVQMGVPTMFATTELPKREKQQKVMQVLEGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU69</accession>
    <name>A0ABQ8VU69_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_85547</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease H1 N-terminal" evidence="3">
        <location>
            <begin position="9"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="4">
        <location>
            <begin position="110"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="24519" checksum="3A19FDA4B4DC0752" modified="2025-10-08" version="1">MPKASKKSYYAVCIGREGPKIYNSWDECKQNTSRYPGAKHRGFSTYQDAQDWLASAMSLSSNLGRKPSADSDSEVEVQMPPTPISDDSDIEIIDTPPLGATGSSPTEIVLSPEQKKVLKKVEKGENVFFTGSAGTGKSVLLREIIRYFRSTNKKVAITASTAVNIAGSTIHSWAGIGLGEEPTKTYVGKFRGQKKLRSVWDRWRNVHALIVDESEDTLSRACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU72</accession>
    <name>A0ABQ8VU72_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_907845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047520528" evidence="5">
        <location>
            <begin position="21"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="114"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="73"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="424" mass="43964" checksum="054BEF76E7FD89CF" modified="2025-10-08" version="1">MRPTAFALVVILPLITSVIGTPTSTPPSINAKIPLSKRASKLVNDQGVVSASALQNELARTRSKLARGFSAFQRNTGSAHPSDTRNLANSTDLNNRKRATGADPLTDDEDGSLWQGAISVGTPPVHFTVDFDTGSSDLFLPGQNCGTTCRGHTIFNTAASSSAVNQNSRASLAFGDGSTVNADIFKDTVTVAGLKATSQTVGAATQYSPGFEIDEFPPDGLMGMAFQEISVFQAAPVFQTLVAQGVVTAPEFGVKLATTGSELFLGGVDTALFQGDLTTNPVTQVGFWQIDLQSVNVNDKAAVSDLSAVVDTGTTLIVGDPDNVAAFYAAIPGSKDASETVGPGFFTVPCDDIPSVSLTFAGKAFTLSPDTFNLGLVSLGSNDCVGGVSASDLGNFWVTGDVFLQNVYTSFDVGNTQVGFATLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUD8</accession>
    <name>A0ABQ8VUD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bola protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_753197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052275">
        <property type="entry name" value="Mt_Fe-S_assembly_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188:SF1">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="111" mass="12359" checksum="20A55987691400D5" modified="2025-10-08" version="1">MFSLSRHCLRTAVQVRRFSATSYVSNADTTSTQGEQHIRAKLTEKFNPTTLRVQDVSGGCGDFYAITIASEAFKGLTMIKQHRLVTETLKKEIEGIHGLQVCHILSVNGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUJ6</accession>
    <name>A0ABQ8VUJ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_875627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045828937" description="Secreted protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12486" checksum="AE36423A74C4997C" modified="2025-10-08" version="1">MLAFAFSSFLIALLLIYVGAGPHVLASIMALDDSLGAHESGLAVVAARNPFRDSGPPANMAKLILLRHKIQTTGRKRRSTSHTRQVSRPYTIAQPRPAKAPWLRFGRSAGKQFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUS7</accession>
    <name>A0ABQ8VUS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="243" mass="28197" checksum="467BD9FA73A50C5B" modified="2025-10-08" version="1">MSRNFVESWCYTDSGFAEDAEEDGADLDIVLRTKLAWHFVPVFRQVMSTPFQKEFLDSLVNIWASHWPEDTTYGRKDKDHRTLLSKRVVWPPGVSSGEFDIEDFEIRHAVSHEEAHIRKCDAVGTFTLECIYSSILKFLKAAVENVGEYIAGVDRPAADWKESLREAVFLWGAHNHLPEHFKQEYPHWPKYRYLVATPPNNEHLLIKWEYPLLPSPLWYTSPLPSSDEDRAPTPLSPWIGRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVN4</accession>
    <name>A0ABQ8VVN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_488300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="59"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="390"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="416" mass="46720" checksum="813188E3BE6088B8" modified="2025-10-08" version="1">MEGFGSDEFIANVMVALETSSLTFETHTTGLSLLNSAKCYRPLQSDSTRDDQVKQGLVLLMAHGTGYHKEHWEPTIEHLFDLESEFTSTKTPPTPTIRECWAIDVQNHGEAAMLNEQITREKPEAWSIWDYADSFVTLRRDILGSNPSYRDNKFVLVAHSASATAAILATTFFPLPILQTQNIFHSLVLIEPAIAPTPAFVDSALHTPLYRAISLLMTNRKDTWASKEEARVWMEKKIPWGMWDARVLKAYVDFGLVDNAKGGVTLSCTRQTEALAYERGIRQSLPGLWQLNLLCSANAHVGDNEAGTRTASKTKENYKPIIPIHIVWGDIDDLFSREMKDRLEDLEQGRVFTSVTRVEDVGHMMIQTSPQATAKALWDIFSESTPDAVSFLGENSEDQGTQKPRNPRRGNLHSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVQ7</accession>
    <name>A0ABQ8VVQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_863430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="18790" checksum="EF30E194AAF68A53" modified="2025-10-08" version="1">MVAKCERNNSTEMTTQRGVEASASFKLQYFNLHVIGVKWIRGKERVTTTATLKKRRRIWCPYGVRGQEGLDEAYEEGEKGEFGGGGGGRYRGGKWNHDTDVYHTATTVTTGNTSTKGLGNDRWIADICGGAGRTSEAKLYENRDLSTFSNPDTAIATAWSPYRLLTQGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW97</accession>
    <name>A0ABQ8VW97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_810514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="115" mass="12972" checksum="197B26714611268E" modified="2025-10-08" version="1">MPVSVQLPSLLEPITSSSTSLTPTPSTSNECGIVLLPPLPHAHRTVSKEYLRTENMVMRTQLEATGKLLSANFAHMKLMEAENERLCNKAFAKKRKHVARLWQTNLKTQAQRHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWG4</accession>
    <name>A0ABQ8VWG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_788024</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.20">
        <property type="entry name" value="Gas2-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003108">
        <property type="entry name" value="GAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036534">
        <property type="entry name" value="GAR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02187">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00243">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143575">
        <property type="entry name" value="GAS2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51460">
        <property type="entry name" value="GAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAR" evidence="5">
        <location>
            <begin position="1546"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="613"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="990"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1344"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1653"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1353"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1394"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1430"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1452"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1480"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1498"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1659"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1672"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1683"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1717"/>
            <end position="1738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1744" mass="194500" checksum="BB6D5514C417CADD" modified="2025-10-08" version="1">MFEDTTIPGDGSSGTTVSQADSIHINSINAVNLQPELPEVPTKARAGGDEEALESHQVIELQIFSERKAWIEEKIKLLEQMPPIEVFVGLDAVQASAEVVPGLPTREELKKWLAEHDTLEKETEIFDTGELKKLRNFTRVATQRNLSPEDTDLIELTLTTIYALDKLLHLLRDRSEMLDLLGVRLSWEENRISSWVDRRKIIVDLQAFLESRAQWSASVYDNPPKTDPTLEDHRRGSVSSLTSVASDTSINSPAFSRSTRFRLAELLSRDAATFSARVSSLRHGSVAASGKFLDKLIDNSRKPVPEVLLDEQDRIDEKCVNDLENIGKFVLNVVIQWRKADEIYVETMKDQFAAQTLLEDIESAMMQQPTARQSAAFMTRSDALLKRLLLRGNPASSTSTFPRPSHPLFTRQSEFNESLAQTLSSEIKSTTELLGNVESLTKMYRASYDAVSRVETLNEAVSSLILTFQSIINRLENGIASSEGDGTPPTLMSNECLDPSRHSVFIALLPSLLDELAKTDHSASELVRQVPAALLHLDFPGVDQEFKTNASTQLLRIIALREQAQRLNEVTVGRVGRLREARRIWTAMDATWKEVEAIRREAVDEMDRCRWRQDTTTNVNGAPPTPESPSTVPLPSNSLQQYTELEHQMTQLGARLQTVVDDPLTSFSTTLELPLKEHLSQSAQNLKSHFIRVQRMIDLLQSIHKQTTVMNGIREEFNALQLRLDDIMTRYESKTEDILDDTPIDEQVSDTDESLSSEFTATRSNAMVFINNLAQRVPLVGSSSQVPIVKRSFSTIDLTSTTRPEGLLIELPFDLHSVDDSVRADCNSYAMRLNGQVHALEQEVHHFYLSHIAKELDASTSTLLNEIDQASSQFSTLHGTFTGLQDAIDVLNSLTKLTADIEQSSSTHRGRLNRSLAAVREIHRRLESAPGILDSNVHDRVLLSRTRGISQLEGQITSWEAKVESLRAQVVAAQEAAVYRMQREKEEEEARLAAERERAAKEEAEHAQAEKFRQEEEERRRLEQARLAEEEERARLEKEKQEETERIKLNEIRLAQEAQAKEEQKKLALEEAEKARLEKERIEMVSKLKDTEGKLLAERKLHAEKERLAAEEARMARLEREKLDEERNHAIKELEAANISLEEDVFGVRITPADGHSPMSTEIKDVLALMARLRKRLRSIGINDAARPQSSNSALPRADRARVMRQELMTLKQEVGSLPDNVEVVSVNVQLKSLRNDIETSFTLLDRIDCLAALSEVLCTCDDALSDLLEHIDSFPATPLGPLSSSHTSLSSLIPEEQLSDRLSFTKSTIEAVTNAFEVVKGDPRAIVENERVLQTWSELEEMGNDRVHGTKSRPSSVMSTQSSGHDSRVSLNKSQLRFQPGPSISAKARKSGSYATLSVSSTPRGRLNVPSPTPSQSRRAFSGSDEPGTRSTSRMSTRSSQQRTVSGGSLYGTTYASRQRTTSLTGAAATPPPKRNFSGGHTRSQTATASQKKRDPSPSLSDASLSFNGRSSTWSKAPRISFTGVPRVSTPQKRPSAPRKAYVANPKSKLDVAVGDVVNSLPIGINIEGVSGSWKDQSGKYWIGDQEPKLCFCRILRSQTVMVRVGGGWSELSKFIRDHFADSFRLLAAPDSPGMHTSGEERWISSATLLEEREQNTPPGPPRTPEPRGPLLPSFSLSTPSGHSPQSMMSTPSTRGSPLTPLQFMRRAEPEAPFFTRPETPTKSPSRPRTIPTTPARQSIWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXM8</accession>
    <name>A0ABQ8VXM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF39">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="89"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="318" mass="36582" checksum="922C16A217CB6C8A" modified="2025-10-08" version="1">MNQQIEWLVYTFLSITADVLDTLLSCVISNSKPRLSLQHSDVDDLSDEEILELRMKAPRLNSDHGVVKLTPSTVAKASQDMDEDMSDASEANALKLVFAQTIIPVPRVHRVVKRKWDYLIVQDYIKGPTLANAWSTYTIWQKIGVAFTLRCYVRQLRRLKASPSTPPGPIGADGPRICESPIFGQVQSHRGPFASYAELTAFFNQRAKMAYDAIDLPEDHPSRKQRFDNSEALVFTHQDINPRNIIVGEDGRLWIIDWAWSGYYPPWFEYVAMSRQLENEEVIGSDHKYWDLLIPFVCGPYFEQDKWLSKMSRGLYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXQ9</accession>
    <name>A0ABQ8VXQ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carboxypeptidase S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_190982</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05674">
        <property type="entry name" value="M20_yscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017141">
        <property type="entry name" value="Pept_M20_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047177">
        <property type="entry name" value="Pept_M20A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962:SF1">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037217">
        <property type="entry name" value="Carboxypeptidase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="300"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="608" mass="66395" checksum="36CDB2157DA54824" modified="2025-10-08" version="1">MVVKSLNHLPIPTSANISPRSVSTRRYVAGVVFGIFFSLQLGRYAFDLGKNLDITVEDVTSWTHNVDAAQFCPQVTALYPQSSLNAETWTEFGELLETEKFKTLAIERLSGLIQIPSESYDNMPPPGQDPRWETMGQVHDYLAVAFPLIHSTFSLAKVNTYGLLYEWTGSDASLKPYLLAAHQDVVPVNPDTLDTWIHPPYSGFYDAETGLIWGRGASDDKASLAGIMLTLETLIGKGWTPKRTVVLAFGFDEESSGIHGAKTLGKALEEIYGRDGLAFIVDEGGGFKDVYGTIFATPGVAEKGHADIKVEVTSPGGHSSIPPAHTTIGYLASIISELEQNPFPVELARGTVPHDTLLCYAAHGHDISPRLKHSIFKSTHCDAALRRVEDLYVSKDHWYSSLVGTTQAVDMIYGGVKANALPESAYAIVNHRINTVSSVNETAAHDTQTVSGIARSFNLTLKAFGQDIIPASAYSSSGPKGHIELSQAFNHELEPAPRTPTSGTGSEPWDFLSGTIKATYAAHRNLRGIDGSNIIVSPGMSTGNTDTKYYWNLTRHIFRYNHKNGAYGGEIATGVHTVNENIPLDHYLEMIRFFSTLILNADEVKSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXT4</accession>
    <name>A0ABQ8VXT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_191861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="879"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="630"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1059" mass="109151" checksum="7EEB602C43F53013" modified="2025-10-08" version="1">MAVPESIPRAHTALGSLAIVVDSSVALAGIWHTILKYLGLFVQRLILTNHGAGYRIAWVTYGPPDSLSSPLLCKRFFAEIAEVTNVIKAQDELYQLGVGTTHSGGTRGMAMLEGLVAAVESPSHILHITASFPDNAKHPHENMSSLLDEVTWETLPAELSKRNIFLSSIVLNPKNNTKIPEFHSSAALNTAPTSWLPVDPPHKAYVALLSIPQKGVKRPADQMNAIEQPPEKRSNISSGSPPRNNPKVNVNANANPPVTTNSAKPPSSGTPSQPQPKPSNAPTQSPAGQPTQLVPPSNLVNLPPPNSTQKIPWPGIGSLTPNELFQRLRYFEDMRRRTDAVLTQAINSGDSSKVEMVKQQTAQWEPMFFKVRNMVSHYITALRRAGMAGPGAPGQGQASTLTGVGAPANNLNPNPGNADISSQPLTTQSNSHPNPPSSSNAPIASSPATKPNDSLMPANSSITSATSPGLSAPAPSSSTTSSKSPSKPSPKPSAIKPSPKPKPKGSPIKNAASTAPSSIGVSSTAGSSASTNPVVDGSGPNLASGIPTPSSLPPEAALQMQKLMEQGGRGHPRDMAMGSMGQVSPNVTAAGVAPQPSPQGMQGMMPGQGQSGQQPQVGGVVGPVGLGAMSSGSVSNTPSSSAGGPNGGIPAWTGGLFYPGEPNGTRKDFRISVMAMSANHLECRAHTWPMEMTLTHTRDPVVSLAEFQMWAKKTRPVVCTIKPHARNPDARQNAFNENYFNGIQALIRQSKTYVVSSWTLPSGAQTNNVLFAIVPPHGFIGAFFPVTGIPEMPKPIPGSTMPGGLLGRLPGGVTGESIGAPPAGGATGPAPGTNIGPPNILAILQSFRVPPELTTRILQMPPERQIMALKSLAQTKAQLRGQGPGQGGATAAGGQAGTAGMHKSGGSNVNITAAAAAMALRMQSGGIGVPQGGMQGTTGLNMAGIQRQLSGQDGNKPNPQGAANIAALINGMRGNMGGMGGMNAANMGGNIPGMGGSGAGNMFQQQMAQMQQMQQNRSVFGGPGGTGAGGVGGKNLSMDMIQSFMHRNGQEGQGGGQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXZ6</accession>
    <name>A0ABQ8VXZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable beta-glucosidase G</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Beta-D-glucoside glucohydrolase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Cellobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Gentiobiase G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_941955</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106882" description="Probable beta-glucosidase G" evidence="14">
        <location>
            <begin position="20"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="15">
        <location>
            <begin position="716"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4501200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="796" mass="85176" checksum="998C190C1BBB20F3" modified="2025-10-08" version="1">MFSARLSLAVLFSVSPALAHFSGLGLGSERSIFRRDLNSTGDESNSTQWPAPLANGGKSWASAFKKAKSTVAEMTVEELANITSGVVGLCVGVTGAVTRLGIPELCLQDGPIGPRGVHGSSQFPAGLTVAATWDRTLMYARARGMGQEFHDQGVHIALAPVTGGPLGRTPLNGRGWEGTFADPYACGEASYQSVKGLTDAGVATVSKHWIAYEQETSRNLYIEFDGGKISSNLDDLTMHELYMWSFAEAVRAGTNHIMCSYNRINNTHSCNNAKGLNQLLKTELNFQGGVVSDWGGQWDSVLSAENGLDVGMPGEGFLGELGDFWGTTLADLINNGTVSEDLVRDKVVRLLTGYYHLGQDINPLPPFVYNTIGAPTLNATSGYRNVRKPGTAELIKEIGSASVTLLKNTGSLPLKHPQRIAVLGNDATYNVLGPNACGLGNSACDINNLNGTLTTGGGSGSALSPYTITPLAALQERAIEDNAEIAAVVANSNTTIGAEDAIAALLPDADVTFVFLNRYSEEGADVPDFALGGDGENLMDLAVTYSSNVVVVIHTTGVVDIEKWADNPNVTAILVAYLPGQEAGSSLVPVLYGDVAPSGKLPWTWGKSIDDYAPNGVVYTDAYSPQSNFTEGVFIDYRWFDKMGITPRYEFGFGLSYTTFTYSNLIVDHGRWAKDYSSVMETAEPFAEWDGTNSLYDVIFTVFATITNTGNLTGSEVAQLYISIPGDNQPVRQLRGFDKIKDLPSGDSAVISFPIRRKDVSSWSVVDQLWYVPNGDFVISVGGSSRDLPLNATWTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYS1</accession>
    <name>A0ABQ8VYS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_862409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="21347" checksum="7D614B8CECC6E91C" modified="2025-10-08" version="1" fragment="single">TEAHAADMRQYLKETLRYVKSPQPVPLESPQPVMLKSPQLVMPKFPQSATPKPDTRGEDGTMRAQLKEEHRVCVSGVVASGRPWPHGMIVKDMIDSFTLVDSHYWKSRYPHNQQDRINEVFQGVSVDKRQFHKQRRAWQGMTRDEWAYAQSGGHEQEWVQWRKTSKGWKEENERNHRRIAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZE4</accession>
    <name>A0ABQ8VZE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 30 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_363951</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="177" mass="19533" checksum="1DE1915228942FCA" modified="2025-10-08" version="1">MKASRNEEDDSDAYDSDAVLDPREKARRLKEKELNSDLNNAADLFGAAALGGTTSKELDSLLSFQPRTKEDFVKLSTLIIELVMKRHQNKPLYPTFVEHHVRELAGPLKDVEVRKAASGLTTLANEKQKEARDKASGKKKKAASKPTLGSAKVANKVDTGVYDEVLDDFGTHADDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W051</accession>
    <name>A0ABQ8W051_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YjgF-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_806324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857">
        <property type="entry name" value="BLR7761 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857:SF1">
        <property type="entry name" value="YJGH FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="136" mass="14901" checksum="93D5764FB77372C2" modified="2025-10-08" version="1">MSITLEKNGATYFRTQNPFEKNFGFSRAVRKGPFIFVGGTTSFDPESGEMMHADSAYGQAKVIFETIIKSVEALGGKKTDILKLKLFTTTMECGMEVGKAFKEIFEEIHPAAILILGVTLASPDMKLEVEAEAVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1M4</accession>
    <name>A0ABQ8W1M4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_805522</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="31954" checksum="F4E219478C5A5A68" modified="2025-10-08" version="1">MSERKVLNKYFPPDFDPDLIPRRKQPRNSQQVVRLMAPFSMRCNTCGEYIYKGKKFNARKETVEEEDYYGIKIFRFYIKCTLCSAEITFKTDPKNTDYAAEHGASRNFEPWREEEAGEEEDRLAKLEEEENNPMKVLENRTTDSKREMDILDALQDIRARNARNERVGNSADLLAKLDMEEIENEEDLERKRLEEEDEKLVREVFSKIPSMSGDSPSEIVTVKRKADAIEPSVHSLLSESSRSLLDLKKANVQHNTAKKVKKNTLGIKVVKKQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZZ02</accession>
    <name>A0A9W8ZZ02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_524368</name>
        <name evidence="10" type="ORF">C8R41DRAFT_895829</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000036">
        <property type="protein sequence ID" value="KAJ4469097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZZ02"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000085">
        <property type="entry name" value="Putative ras-related protein rab-11a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4469097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4491808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="211" mass="22982" checksum="8C86DFAAB0C670C5" modified="2023-11-08" version="1">MAEGSNYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSINVDGKTVKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHATYVNVTRWLKELRDHADSNIVIMLVGNKSDLKHLRAVPTEEAKAFSSENGLSFIETSALDASNVESAFQTILTDIYRIVSSKSLESSTKDVVDPGPSISVGPSVDPNANQGSKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZZL0</accession>
    <name>A0A9W8ZZL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_177397</name>
        <name evidence="1" type="ORF">C8R41DRAFT_853228</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000030">
        <property type="protein sequence ID" value="KAJ4471049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZZL0"/>
    <dbReference type="OrthoDB" id="2585179at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="91" mass="9700" checksum="94BF971367E79A13" modified="2023-11-08" version="1">MNYDLNTYVAVTLAPNSPFLGAPSSLSTVHPALTHVGQVGQLHDVQLVSVPKEDWSNIGDDILASLKGSEGVSSVSVQELRQRTKRGGDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A208</accession>
    <name>A0A9W9A208_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8J55DRAFT_521015</name>
        <name evidence="18" type="ORF">C8R41DRAFT_796264</name>
    </gene>
    <organism evidence="17 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000028">
        <property type="protein sequence ID" value="KAJ4471797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A208"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000001">
        <property type="entry name" value="ADP,ATP carrier protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="11"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="115"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="215"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4471797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4489227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="312" mass="33468" checksum="B79B1DDA22A4476D" modified="2023-11-08" version="1">MAAVKKGKTPQDFAIDFMMGGVSAAVSKTAAAPIERIKLLIQNQDEMIKQGRLSHPYKGISDAFKRTSADEGVLSLWRGNTANVIRYFPTQALNFAFKDYFKSLFGFKKNEGYWKWFAGNIASGAGAGASSLLFVYSLDYARTRLANDAKSAKGGGERQFNGLVDVYRKTIASDGVAGLYRGFVPSVVGIVVYRGLYFGLFDSLKPVVLVGPFEGSFLAAFALGWVVTNAAGLASYPLDTIRRRMMMTSGTGQKYASMFDAGRQIVAKEGTASLFKGAGANILRAVAGAGVLSLYDKAQELMFGKVYSGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9APM2</accession>
    <name>A0A9W9APM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_424694</name>
        <name evidence="7" type="ORF">C8R41DRAFT_781905</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000010">
        <property type="protein sequence ID" value="KAJ4486662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9APM2"/>
    <dbReference type="OrthoDB" id="430207at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4465350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4486662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="176" mass="19705" checksum="17004ECD32CD8479" modified="2023-11-08" version="1">MASMLRMYNVALQRRPMFTQCCTAAFLFGAGDIIAQQGVEAKGKNHDFARTARLTFYGGALFGPIMTKWYQWLNTIKFSSPTKAVVYRVFLDQAVLTPAAVGFFFGSMSILEGKPKEAIPRIQAAYVPTIIRNWGVFVPTQIINFALIPHHLRFVVVSVVSLFWSTCLSARIPLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWD9</accession>
    <name>A0ABQ8UWD9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_141573</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000152">
        <property type="protein sequence ID" value="KAJ4463814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="115"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="318"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4463814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="47533" checksum="E0DC7A9B4F614B31" modified="2025-10-08" version="1">MSHNGYGGGSYGGGGGGGWGDDRMSNLGGGLRSVDWNHTKLEHFEKNFYVEDKRVSARSDREIEEFRRAKEIRIQGRNVPRPVTSFEEVGFPEYLMKTIRAQGFSAPTAIQCQSWPMALTGRDMVAIAQTGSGKTISFALPAMLHINAQPLLAPGDGPIALVLAPTRELAVQIQQECSKFGNNSRIRNTAIYGGAPKGPQIRDLQRGVEIVIATPGRLIDMLETQKTNLRRVTYLVMDEADRMLDMGFEPQIRKIVSQIRPDRQTLMFSATWPKDVQKLASDFLTDMIQCNIGSMELTANHNIAQIVEVCSDFEKRNKMITHLEKISSENAKVLIFVATKRVADDITKYLRQDGWPALAIHGDKEQRERDWVLGEFKAGRSPILIATDVASRGLGMFLSFLLQALRLFFLCWCHPCGRRVCLTFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY66</accession>
    <name>A0ABQ8UY66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_96846</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4465612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="512" mass="58403" checksum="A5671596DEEE830A" modified="2025-10-08" version="1">MWNTVVLSMGIILVILQVFKRLRLRSQLPPGPSGLPILGNLFQIPISQPWLTFDKWTKQYGPIFYLNVAGQNTVVLGTPKAAADLLDRRANIYSDRPDYVVLNLITGGMHWAWTQADDLWKRQRRGAHEALSVQTAKEYFPYQETESVIMLDQMLTDPEHFLDHFQRASTSLTLSIIYGWPPLLDSAHPNVLQIDQMNRQILVAAGLSSFWVEFEYFKWMKHLPRWMCAWRRNAEQAFGYHSDVLEGLSADVQKRIDAGDESKSVVGKLLWDSKNLFEAAWNSASIYSAGSETTAGQLAWFMQAMILFPDAQRKAQEELDRVIGPDRLPSFDDYAHLPYIRATVKEILRWRGVAPLGLPHRLSRDDYYEGYLLPKDTICFVNLWSLHHDKEVYGDDAEHFDPGRYLDANGKLKSSIADTKDEGHYSYGFGKRICVGRHVANNSLFIHIAFLLWAFDITAQVDEYGKHVLPDPSQCTEGLTVRPTVFYCNITKRNMEVAEIIAQAKADRGIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZF3</accession>
    <name>A0ABQ8UZF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyketide cyclase SnoaL-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_927075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="131" mass="15517" checksum="F4D85148CC56B3AC" modified="2025-10-08" version="1">MDIGAQYRRYISYLNEGRVHDLGDFVHEELIYNDEPMTRDDYQNYIADDFARIPDLHFDIHQLIVSDNHVASRIRFNCTPEADFRGHAPNGQKISFVEHVFYQFENGKIRQVWSLLDDRAIHAQMEKETTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZH2</accession>
    <name>A0ABQ8UZH2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_871512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21245">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="75"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="213"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4466975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="36575" checksum="BC698D2A4AD08B14" modified="2025-10-08" version="1">MSESDNWRVKKKLPSPSTSSNSVSDNKFTYQTSPNRPREHGSGSAIQTQQRKTWNASGQRTNITHDASKAIEEGRRVYVGNMPYIAKRTDVEKLFEAYPVEHIDISIDPFTGRNLSYCFVELLTKEDAERAMERLNGQIFVGRPLKVRPGVPRGTRQNNDEENGVQDTPSQGVNRRPRRSPADFANNLAAALVFEGWERDDAEMHWKGADQGRRLYVGGLPQMTTHRAVNDAVRDIFKGYELEAISKRITPNPPRPGNNYYVFVDFVRAQDAARAVKVFNGKRALGSVLRVSHAKGNSRKVDERERWAENEEIANDEGRDTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V071</accession>
    <name>A0ABQ8V071_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_898196</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="10"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4467774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="475" mass="51842" checksum="1A8AD58CB946278D" modified="2025-10-08" version="1">MEPSPLPQAQLITLCLVRIVVPISFTQIFPYINEFIEFLGVTDSSQIGFFSGLVESSFAISQLLFIYHWARLSDRFGRRPIIIIGTLGVAVMTIVFGLANSIPELIVYRCLAGFFGATASVIHTVLGEITDSTNQAAAFPLYGSFCLSFSTTSRPLIGGSLSNPAQKFERIDHAEGLYSRIVSFFYLHPYFLPGLVSGIMSLMGVALAYFCLEESLPTKRRFPTSSSQTDPETFAGANNESEDNASSFPKHPSARILLSIPIIRALSLSGFALEMNGTSFVVLFVLFCYTPIEQGGLAFPPSVIGYALAFTGVVAGLTQLFLMPVFLRRFEAAKIYSVCMAVWPLVFLILPCLNIIARYGSDHGLNGGLTPLSTHTKAILWVGFFVTLTLSRVGGIAYPASMILIKNNVPCPEYLGSTNGLVQWFMCLSRCVSAAFARYNIMGGHFWAVLHALIAVLGWWLARSISLNSKSTLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1E9</accession>
    <name>A0ABQ8V1E9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_631500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="39089" checksum="7FB5DB82CEBE88C3" modified="2025-10-08" version="1">MGRPLWSTVYNPRSTEIPTKTPGKWSSTNTFDPDSDAFFYGAELEVPIADAPVMTEPDTTLSSFDWTAASSVERLNSLAELVAERRRELLDVMVRRRRIEALDSIRRAREAIATQRQTQLGETLPVARESSTSSGHPSVVTPSAGYSSGTPLSPLSESRLTELQNEPESDEEFIEVPMRFAPPVNRRSRESSLSSNRRDTSRRHSDHAARQAFINSLREENREVALEIERRRNRLREQAQNQRLEDEGSSVDRTRVSSLSLSRQRRESLYSRLSSAPGQPDLRSRVLSTPPHTTASASEQAATSLELETEAEIRRSMAIAQSVFRRQRHREMEARNRIPIADFGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2B3</accession>
    <name>A0ABQ8V2B3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="20926" checksum="9C9FF56BBC49A574" modified="2025-10-08" version="1">MSFGSDPESFLEYALSLPDPVSPDPETSDPSDQSSPSDHNSEQESVQSGTNSDSDQSSYDSEFPGPFDYDYLYQSSDFDSDHPGPYDLSYLHSYPSSSASDSHESFHSFASEASEAPELRPGDDRSGHPHLGPDGRLVDSERERRRVLGLCFYCGGEHMKVDCLKLQARTGENYDADDSESDIPGSDDGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2G2</accession>
    <name>A0ABQ8V2G2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_852176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="100"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4470311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="369" mass="39574" checksum="20497F10B49AC5E3" modified="2025-10-08" version="1">MQTVPSLAMQPNSSTTSAIVWKDRTNIKATYQGRSWVLSLTSQPTSMRRVIDRAIKEGKSDLVMGHEICPLEPEGLKHLALKKLVKAADFFGWDGAADVAHRLEAGDHDSYIKPLTTYVSSRIGNECAKELKGPGLNTVVVNAYGFTGLSGPSAAQRIILTRHFMYGLDSRGNFDDTKPFQHKAYADYIRTVMFGNNLYSGVVAANHARFVSSIKTKPSELEVTKGMVAIATAGIHAMLQDYANGQSRGKAASFPLPETPGIWSSALSVLNNIERVNLPLYHKIMHELYLEASGAVPLNKGGVTQENVFDTVNWAALAAIDVDHSNTSPVASTSSLPATRTTSGIPVLSAATSPSLNATTGSVPTSPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2I9</accession>
    <name>A0ABQ8V2I9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_856862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046071811" evidence="2">
        <location>
            <begin position="24"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="33042" checksum="A6B13292FA206F39" modified="2025-10-08" version="1">MPSFNTFQFVFFLCFGHFSGVFTAPVPRWNGNHHWSSSGSSVTTSASPAASTTTSWDINGAPVTIVSVSQGPALTLGTGSTTVVGSSTYTVAPAPTATTTTSWDFNGAPVTVVSVFSGPVLTLGATGSTTTVNGATYTVAPSSISVSMSTSWGASGAVTMMSASGGPELTLAASGQTTTIGSSTYTIVPTSVVSSSVSVSTSTSWGPSGAVTMISASGGPDLTLASTGATTTIGTSVYTVISPSAPSVSTSTSWGPSGAVTYISASGSTPLALATSGFTTVIGSSSYTVATTTATSSHSPSNAAGSLRPFVFSSVLVTGMIAMVMSTLLGGFVCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2N3</accession>
    <name>A0ABQ8V2N3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_851408</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045552449" evidence="3">
        <location>
            <begin position="23"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4470999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="406" mass="44850" checksum="85FDA6BE9BBB7BFA" modified="2025-10-08" version="1">MYHHSSLFTLILILLTAPLSQCIQFSHITPSAGNNNSSAPSSSSLMLNWTREPYDPPFWAVNAIFTVNGKLSASNGLGFEFIVVPHSPENSGTIQIPVQATANITVLTFTFTLPQHSKFSGKIFGQPFTFNVVTEGSSMPNISTGILPPMVQNMLTPTPTTTHKVATIIGAVIGLMVFLCIILALFILRRRRHRRRARIDAETFLRKHNALYRPTSLPPTLITFDEECHHVEESVGHSSTAWSEGGSEKEPLYGYPNDYLGHATTHISPSLFRKPDTVSTPTPRARSLNNSISSRTEKLGNDSTSESVPSIALPIPQNSLAPNRTLLYLQSPHSPSPSYLFLPQSDQGYSIEQSLAQLRGRMKLLLKQLDSESLESGRDSTEIGDEAEMIQIKLEMGRLQRILDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2T8</accession>
    <name>A0ABQ8V2T8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_853269</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="335"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="206"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4469135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="382" mass="43131" checksum="CC1B6FD2F0CF0CD4" modified="2025-10-08" version="1">MPHGHCQVCLGYFALSDFQVLPCGHGGCKYCLGQIFDTVTNMGNCWMCRQEFHRSGAHRVHLELVDSKVANFQNTIEGLERMDASVPSISVTRASTKIKRTVDEINCDNEIAVSLRQAITDFDDRIVPVFIRVEAQAKDVEQLQKQLKCTQGKAKAFEDVCESSRKKDALIIALRSELDRSDKEGRQAVSMTESLTADYLASKRQNELDTEEKKRLEHDNRELRRLLECHAKSAQSRKDKIQALKHEITKLKQRNEALEETQSSVSDETLSTFPLNDYVDETLPSSFSSSARPTSPSEHFRNKSYRSSRLSHVTNELSESEVDVNFDFGMPGPGFSSDWKMSSTTKSKKRKAASLNFPIPLDKRGRPIVSVQTGPVRSRRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V303</accession>
    <name>A0ABQ8V303_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="693" mass="77027" checksum="15D7F339375C77CF" modified="2025-10-08" version="1">MEFPRVNHNINLVTLPQSPMGIISSTSAHSPNDAIVIETLITDDELPGISITNLLVSQRARTPLTPKHLPIKATGLTSTSINRGDIRTYLTPRDKPNVGTSYDSASPILSPTSPSRITVANTKNRNLLPLPNKPVIDLTLDDQDNIIDSSTKSNTFGGHPGKQPRTQLPTYGEITDSQSSSWKLHNGSTSSKESSAKQPRRLSRMVHGAPRDVQKRLSQRPRKFPIHATAAAPINQSKERFSKKPVTVSTSETDDHQEILSTEPEGFAIPSRSFQRSQKLLDVEKQGARIPDTSASSHNVMRNSQYKSEEEEHDLVGALSSAFARNAIPDDFDDSSDFSSGTHSDVAPPKRSRSLRQAIKRVPQIPTSPALKLLRQERTTKGLCVPLSEEAIQKYLDVEYSSVHLPLGVSVAPENDSEYVDPNDELLLDYDSSNELVAMRREQKQLRLYHAPTVLVHNLRFVMEQAESSAGGISRSNPFRQYNVSTMPLTMAYVQRVESHCGYGTLDSIRSNMPDWDFHPKPLKYRIRVAADGSYSNNAVPAESLDVGELVARPEKHPQPENDSETRKRVKFFNNAANLDPSTTLSEGAGRPEFDVIACGELLLKLVKGKVQIAAQELEDIMSFLRNPSLEYMAKKFRQVDNLGFFNTVARHDYDSIWRSLRYIMQSASGALGIPEPIEGALKWEASRVMKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V306</accession>
    <name>A0ABQ8V306_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1111" mass="126461" checksum="6C51B793CD24C44D" modified="2025-10-08" version="1">MSYTIPQPPLSDANRDQMPKGTTSMDSFVDFDFNNGEQRPPNHRKGFSSPLNLFRNRKKSTGDGRENPPAKKLSTVRSADSLNTLDHNSFKASRSRALPPLPHSEPTSASHIASSPSSFDDSTFILAPLRMSPQPDEWSTNLDTSKVQVASSSSYEGLPNHYDQISSSLPLHANHGLPIIYPPQRQPPNTFDAALQENGQSVIDESSMLDRNVAPALFVAEGLKTDTPHPHHKHSIEVMKNIAFGGATHLKEAEEALDQFTASPVWTEGKEIAETLLEPAKDVVQLFDALTPLVPMFIIAKSVFVVIVQKELDQRQNDKNMTKFWYTLCDSDIVFKVQSKPYQNFHELTEKVVGKMNDFGNFQNLYRKHGHIGNLYNFWFAPNSKLSALVHTMKSGAYKIQITDFIDTFKDFQNQLQQLLTQVSALTINTVNEKTDVLNQKLDVVIAAIKSLTPAESRVQAKIDDFGGEEKAFQASQIFFYHILINEFGIKVTPQLKSILREDLAIQLKSNEAMFKLQLETTQRDLEQSMERNTDAILTKLDAGPHELIRDEDIRQIWKGNDPDMKWRLSCKTRHFVDASALHHYYVQKFTQYRKMTGETHKDQWTLRFTGRVICKWILPSPAEVLVNLTEPTPAVQPAIGDAIDMDASGYVSIDEVNRFTAHCPLNWSIPVFLAQLVLEISIAGRSIDERWVVRPPDGIKVHLSTQFSPLSPVHHVVLKREPEPRPFLQDALQKIDHRAKRMLPPNRKHLRPYFQDGCLPEIWYIVDSLNTDTFKYQQEDMRFQFEKLASYRKEFMQATYTRLQNNLVNVKYRMVGSEDVRAVMGTSRCEAMVLPLLMLLLERHAKIFETADNFILSDREFQDMTTSMQSIVYAFGRRYSILTEGWRQQRFDIPLQMSCFSYGIFVNWHTHFSSIPFEHSDLHLQEYMPRLNDFSQNVAHGPGPVKDLLTYDLPLQPNAEELRRLRSSLKARIVKKEDAKTRERHGNFSQRVKSKRSSRLGGSAPRSPTIKIDTDIQKSLHPSSAASPIQRKRSSSSYEFEFEDTDGVLHAINVNDGNASADSDSELPDIAYTKGKILTLDDRIRSMEGELSSMKTMLAQLLAISKSQSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3D0</accession>
    <name>A0ABQ8V3D0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_779756</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4467351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="135" mass="14890" checksum="A470C8DC97BE27DF" modified="2025-10-08" version="1">MGTPHVGSSNYSGPGGRRKSNSLPVPIPIPNLTKKSRGRRVPTASTFDNSTRKSVDLNYSSSGGRGGKGVRVHTCKVPGCGKCFARGEHLKRHVRSIHTYDKPHKCPYPGCGKDFSRHDNLGQHMRVHKDYRSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3J4</accession>
    <name>A0ABQ8V3J4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">TRAF-type zinc finger protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_853502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF94">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="TRAF-type" evidence="8">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4468960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="54376" checksum="4EEC12FBF293B419" modified="2025-10-08" version="1">MNALTYVDAPDQNLVCCICRMPFVDPCTNQTCSHTFCRQCIIQSLAHSPQCPIDRSFLRIEDIHSADPIIRSLVDELVVKCSNEPAGCSYTCQRQLLESHIKNDCLYVLVPCPAGGCAEEVLRKDQVGHLCSHTSVTCEDCETSVRYNELEMHRSTCLKRFYRCEDCETEQACSSRAAHASCCHAAQVRCPQEHHGCPWEGRRKDVSSHTTTCSYEAIKGFFAIQDAQKANLVNENTLLKQKAETLESQLRVAQYELRCVQSALGPWSRIPTSRSMSVLPPSSQLPTPLQHNRTSPSLSYMPPGDQASITQYFPDISFDDSQARSISSAEDQRVPERPNFPHSTQSISSRVSFGGASIQNWQSTGSLPIGSGSRPSQNVVAPLNLNTTLEGSLEGLRESIVTLSTSLDSLGRRSDIALTNETLRLNEEVTSLRVALHGLRMQVHTIMMDRNAQVTGQGPGFDPLFIQGDIQWLPNRSHMQNPPHNSITKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4C3</accession>
    <name>A0ABQ8V4C3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="5">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_858211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF105">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="72"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4465613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="24426" checksum="3A4CAB29A89F946A" modified="2025-10-08" version="1">MSFWPQTPPVSQYRSPPGTPRRRKIVHSSSRSTQGLKTCLPQHISTPEHVQSTLKAELSLNFEPDAWQAHTIHRVLQGYDGMVVAATSLGKSLIFEGTAKLAGSGKAVVVICPLKSLERDQAQHAINKGLVADTINEDTEKTPELWRRVRNTSQLIYISPETTKSDLFRREVWNHHSFRNRVAAAFVDETHVIDEWGNDKFRPVHLGLHCYPYIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4U1</accession>
    <name>A0ABQ8V4U1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_848444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="846"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="868" mass="94770" checksum="801EFA099345861A" modified="2025-10-08" version="1">MLTSYLALKTRKRKREQYDLSHNIAGPSHMHSLPPPPLPVTKSKRARQQERMTLWQRDEVAHRQIFDDAAFDAVSSPFNSDSFSPPHPLDTYLPPAHMSGYPHVKTSSLSSSEWVNSMAKAADPSETHKLIPIPWDIFVPPTPWTSQPLPAPDQPPSGSLQSVPIPPINLPAKPVHAAMPTSSTDINASAESSKKPPPTNIIGMPYARDPDSKRGGFKLSSTTVFESKSHLTFPHKVDPSRSLIMDQLPKLSRTPQWLKSWAIDACGIEPVFIAIDSSSAKALLEFSSVNQAERAWSSPKLGKGLNSLGPIELKGKARVDLIRVWWYRSSSPEVVFTRKELEEGEIEDDESMVDGRKESKKEKRARLAKQAKDEKKKDLVVQSGGPQIKTLSTNPSPMDSPVIHIPASNTKSLPLPPSPASALPQRPFASTIYVPSAAPHVPLLVSPPTSLSARKESTVKPTIRLKNITPTREAVRGPQPPRRFTKHADNAVDIDIPFPVVDHPDDIDMELSSPVVQPSPIPRDPQVVTPENYANDHHATVMKSIVITSNTEDIGTESTRPLGARSNSASNLTHIDYTPSESSTVPSDSNAIQTSSVRSSVVKRSLLARQKELEERIARSKLEIERNQSLAASTSASSPSISVKPPLPSSNSDGPLPNKQAIEVQLRRLVLASQRKKKISDSGSILPLSPSSDTAIDNDEHFLTNSDLVVLSEAGSSDSNSGARISSTSAGAVFDDLAVSFIQESIQTTKPTPALPAVAVKPQSNSSSVGLAARREQLEYQIAETKRLMELLSQTRNRQGRDSIMVQIRELSRSQKQASLPPTSSFVHTPAYPSFLVKPIEPAKPLWPESIPDGGIFIMSDDEDEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4W4</accession>
    <name>A0ABQ8V4W4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_775095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.30">
        <property type="entry name" value="RNA polymerase ii, chain L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039747">
        <property type="entry name" value="RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056:SF2">
        <property type="entry name" value="GEO11084P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="Zn_ribbon_RPAB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4474517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="12442" checksum="C7CA2A68E7E5734F" modified="2025-10-08" version="1">MNTNDDHLQATNSTNAGIPMQVPRQDMEYLCADCNAKNEIRAREPIRCRECGHRIMYKRRTRRSECSALCKNTPANDLVLLQWSNSKPARRRFFIPCMQSNKETNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V557</accession>
    <name>A0ABQ8V557_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">leucyl aminopeptidase</fullName>
            <ecNumber evidence="3">3.4.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_923800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="7">
        <location>
            <begin position="328"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="493" mass="52835" checksum="B2571B951D76EC43" modified="2025-10-08" version="1">MSTSAFIVPIDPKAPATAIPNVDIAKTWATVPRGEKVDVGTTSVFYDTPATKITAASSLGNNFSAKKAEVKRELVRKSVGSAVKALKVLNGLKEVTVDASVDPHAAVLPAVAAHLALYDFSLKTNPPSPFNPNLKKPIPPKLEFKPIESSKEWDRGVAYAYSQNLARTLMELPANMMTPTAFCERAKAEFTGIENVEIFVRDEDWAASKGMNTFLSVTHGTNEPAKFLEIHYKGASQKDAQPIAFVGKGITFDSGGISLKPGEGMKLMRGDMGGAATVVSATLAIAKLKLPVNLVTVTPLTENLPGPSATKPGDIVYAMNGKSVEVDNTDAEGRLVLSDAIYYASTEYKPHTLIDVATLTGAIVIALGELFTGVYSTSDELWEKLHTAGEQEFDRFWRMPLSEDYGPQIYSSNADLCNTGGRPGGSCTAALFLKAFAHGIEAEDGSNAETAMKWAHLDIAGTMDATRPTPYQEKGMTGRPVRALIEYVRGLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5B3</accession>
    <name>A0ABQ8V5B3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_775421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF23">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="189" mass="20109" checksum="C9E7F5A46C847F14" modified="2025-10-08" version="1">MVASEDKDEILLSCRYGELEDVQGYVEKFGAESLAQIRDDNGNTILHMISGNGHTDLLKYLLPLIPPSLLSTPNDAGSTPLHWAALNSHLSIAKELVLFPSGPGVDLIDIKNSAGHSPLAEAELAGWQEGAKWLVEVMNLETVAVAEENGAEDVGDSDIVDPHQDVQVEIEDADGQIARMTISGSAIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5D8</accession>
    <name>A0ABQ8V5D8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_715778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06168">
        <property type="entry name" value="LSMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034110">
        <property type="entry name" value="LSMD1_Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF5">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="77" mass="8811" checksum="4C435EF02A23B8EE" modified="2025-10-08" version="1" fragment="single">LRQLLTSTLRITVNDGRIFLGSFIGTDQPMNILLADTEEYRIDSLEAGQNDREPTPGRFIGQVLIPWKIIRKIEVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5V5</accession>
    <name>A0ABQ8V5V5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_589457</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="508"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="609"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="940"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="758"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="971"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4472673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1008" mass="110345" checksum="09439C1E91C92C52" modified="2025-10-08" version="1">MPSKFSARTWGTRFDSLPLSSPPLASPKSSAAATENVGQLSNPVESPLVEKVEKTSHDASVFVGSLPINVDHKELSAMLSRHLSEFAQVKSVKVIRDSKGGTSPPKPFFGRILRFEPARAYRSLLISYRTPTQKVISTNENTSAESIVELTLPTAMRINKFKSSKSAAIFYNDEAIHMETQAEGISASTHEMSFFQAPVFCDAATLKAICGFFGPLEHFLLLKTPGNDGIDDEDLSSYPAPHDAPRQSHMDQGCFDVKWTQRDDCMSVFMALRRVPHLTVTWAHVAPEREILHQPYPTFPRVRSVLGTGHSSVHSPRGLAPRPNTTDSNNWKIVPQPQSVHPDTILIPQDEPDCNQGAVCPETDFPPLADHKTHFHSNFGGGVWIEKEYSAEFEKEKTERGFVDESTLGTTPPGASPKMLCNVHHLRSDYRSVSISTSIPDSTSQELELQLTPALARSPVTPKTPGSLFPPTPTSFNDERPTLYLKETDDEFSYRTEGVSDEQVLDPTTLFVGGLEMRGAGAWDEGKVYRLFKRFGGLETVKVIRPSSGKAAFAFVTFTNTEGPARAIAELHNHLVEGRPIRVQLRDCNPSRPFRVVRGRGRYPLHHGHQFLRSHQSESKRDKSVDASLGKSVTEVIETSCPQPSPFEPASETTKNAEPNAVGPSHKSDVELPTPQMQEPEPYREWYDVENHLPDSVATPSVGNSFTLEGGPGMPYPFPAFYAPGPWMQQYPPHAHYPMAFYPPIYAVPPNPHPPRYSGSSGSDASGPTSCPPLMPQVPWSASANYGYIPYHGFPQVADSSSPQGQDQAPVVPAGFFRDEAGTLIPVYPRAIIDQYMTNNPSQSNSPPVGVTVTVPATVPSPIPVPPSGPIQAWVPPGPPMFGHGPNQFPSRMGPLGQPSGWITPGQSMNSQAHHAQGFPPSFAMPMIGPPFREGFHSGMGQGNGHKRQGRRDNFHAKRNNGTRGRGSGAAVTNPTHVDGRLNSNRQVSEDWTHWPEAHQGVGIIPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V631</accession>
    <name>A0ABQ8V631_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_983461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="36648" checksum="8B4D5647989DE8D5" modified="2025-10-08" version="1">MVLVALLYSLLNQQTPPDRASYQVRQKRYEFHPINSTPKTRTQHNLMNSTTSLASLPVELVEQIITSFWSQHQSTHHRATFMKSSLCVSRSWATLYVRVFCQDVHIPSGEFALKFLEILRNESPVYSYFTENGTLFDRRCRSLTFQRDNEDGIVEKPIAPDPSRSSSVLFQGFLKNSPTPEHPMGLAIYTVLRFLYFSPHLTPNLRCISLLFNNSTMSDLFTRNRFIGFPTQVTELNIRFTYGPRTSKEVLKKIARNESVVGLVPGSMKKVKVLRFTGLTKSAVRELVLACVNRELVETEDGQWTFGRKKRNITDRGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6C7</accession>
    <name>A0ABQ8V6C7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4473468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="347" mass="35251" checksum="9208A1088177A1DC" modified="2025-10-08" version="1">MDGPNVYIMQRQVLGSVLGGLGSVVSGLGSGIDSAVSGVGAGVTSGLGEITSAVLPTITTPTSTSATSSSTSASSTPTFSSSSTITSTSSTITPTSSTITSRSTSSSVASSSSPTTTSSSSTDILSSSASIYTSTSDGVRETITAFVTPSASPSPSQSPVSNTNGFLNNKPLEGFVFALCGIVGIVILFLVTTFALRRSRRKRMLNEALSYEPTTTHGYTGHTDRDVNEKIRVSYSSAGSSSNGSGPPHSNGSVIAGGYYSAPGMAPQAAHQYEREYPAYAPRSPNPAYDNSRSHGPSYNMSGAPVMAGYIPPVQPAFIQPILATNSTRVPVPAMSPDPAAAAESAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6N7</accession>
    <name>A0ABQ8V6N7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">choline-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_774027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.15" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045049">
        <property type="entry name" value="Pcy1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739:SF13">
        <property type="entry name" value="CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739">
        <property type="entry name" value="CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="2">
        <location>
            <begin position="95"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00026101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="253" mass="27998" checksum="A1CD33EC1CF438B0" modified="2025-10-08" version="1">MDASSILSDDLSDYDVVSDPGRHSLESSIADLTPNPALINEPSPVQEAYDKFATIRLTANDIQVNTRTSLGLAPAASSSTKADRTGNDNRVRRVYVDGLFDIFNAGHALQLRQAKLSFPSVHLIAGVYSDHLCECYGTPTTVPHLERCEILRHCRWVDEVLPDAPWQIDEQFLRERHIDYIVVEEGMTVDPSCDKVRLKGYDAMKRMGKVIPTKRTIGITVVTPASLPNPGTPKSPPIIALFSEETPEPLVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V751</accession>
    <name>A0ABQ8V751_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_847922</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ELOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4474539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="112" mass="12506" checksum="D37139895E913AFD" modified="2025-10-08" version="1">MGKRKKSSRKPAPARVKVPLDTAFTCLFCHHDKSVTVRIDRKEGVAQLICRVCDQRYQSKVNHLTEPIDIYSEWIDAADEAQRVGESSTVRRPAASSSRPIPARAPSVDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V792</accession>
    <name>A0ABQ8V792_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exonuclease V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_844694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EXO5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019190">
        <property type="entry name" value="EXOV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464:SF4">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09810">
        <property type="entry name" value="Exo5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4477986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="646" mass="73037" checksum="EED7E5487579F024" modified="2025-10-08" version="1">MRSYDSTHVLINDRRRFGRAAERSRRPNSSGPPKFQMVDATNVEDEYDLFDDFSDLTEEQLAQIDAATSSASASTPKSIPHIQVELEATDILTETCNDPNGDANGPNKSERVSPLQQFRKNNILSVTDLVSPSWCEVQFDYGLRQLRHRKLKDRPASFVTEQGKEIVVDKGLAAKSDATKKKGVSVHKKLEREIRPEEIKVQVTTEEERWGLRYNTFPASVLQIFRLIPLSRIINMIDCIDSLLLSGCAREIPVFGLTEGNIVVGIIDEITFSQASPSSYNHDKKRGPQSSPSTPQKPKRTRRSPSPSQSRITSFLSPAKASITLSTVNPPSSSSSHLSPPTLHLIDTKTRRTNSLPGDEDTLPSRFQLMLYHRMLTKLMATTDAFDFSSFWQKLELDDIASFSHTFLAQTLLTSETSCLHHLTDLWHIAVSRLNGAKIDSTLQLVYRLQPNRQRSFRKSQKESFTSSREEIEIAKAIEASMRDFQLKSKDEQQLAQALAHSVTDPEVGSSVTEQEKNLVNDPELLWALEQSLLTRLNDNGLDSAAQSQDIQSLPMDNAAQHQSSGNHQSDIIGTKEFEFDANCLDEYLEDILKWWNGDRKPRGVSLEQSGRCFSCEYRFGCEWREQKAREVEEGLKFRRQQKDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7J6</accession>
    <name>A0ABQ8V7J6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_773387</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046890860" description="beta-galactosidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="368"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4476795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1033" mass="112999" checksum="1ABED94790173281" modified="2025-10-08" version="1">MNLLPRLWATIILVLVHKIVASNYTDQVQFDSYSLLLKDQRVFLHGGDFHTFRLPVPGLWIDILEKVKAAGLNSISVYTHMGLLNPSRGVIDFNDWRDLQPLFDAAREVGVWITLRPGMSYINAETTAGGIAHWITSEVAGTLRTNASDYRDAWTPYIQAIASKIRGNEITDGGPVILLQIDNEYNLDTGETYMAQLEATYREAGIVIPFTYNDAGNQDHFINGTGAVDLHGNDYYPQRYDCADPDEWHTVVDYYDYHMQVDSSQPFYVPEMQGGSLNGWGPGSAQYSGCTLLTGPEFENVFYRQLWASNVKLVSYYMFYGGTSWGALPYGYVYTSYDYGGTISESRALTPKHPEIKLQGIFLRSSPEFYKTNRVGNSSIGLPGGSGVSDPSAVAVTFLQNPDSGAGFWIVRQNDSTSTAVTSFALDVTTVNGDVLHLPLVTSAITLSGRESKVVLTDYAYGAKSRMLYSTAQVFFSGSIDSRDVLFLYGNASQSHEFGLALSGFSSSVDVFTATNGTSVGLSEAITVISFSEPFSPGLVTVFESDTQLILFADTPTASMFFAPTISSSTSIDPHKSYWSIGTNETVLIGGPYLVRSASTVSQSRILNIRGDLKLTHQFNGTKIIIVGPAWITSATWNGKQIDLRAASGTSQRHTPSIVLMGTIPAPNGAPVAVKVPTLSGWKFRNSLPEISKTFDDSSWTVANHTTTNIPFPMYYGDGRILYGCDYGFCENIVLWRGHFNATGLEKSVNLSINGGEAFAASVWLNSVFLNTSYGNASASSNILEETDDQFIFPKGVLLPGEDNVITILQVCPGMSKNYFGNGLPNDNMGLNETVLTLNDPKSPRGIRGFRLDCGIFSEWRVQGKIGGYSGYPDKVRGILNEGGLFGERKGWHLPGFDTTDWIGRPLSSGLPNASAGAGFFVTTFNLSVPIGLDVFMSFTFEEELGQSYRAYLFVNGWMLGKRVANLGPQFEFPVHQGILDYQGVNTVAVAVWSMESNVAISPQLNLTVNSIFSGGVTHIEMNNPKWSPEGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7W7</accession>
    <name>A0ABQ8V7W7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF94">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="207"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="383" mass="42925" checksum="F4B17B71DA5B0E1D" modified="2025-10-08" version="1">MSHGASGSCWPRLYTDASIIRSLASLNSSSSRAAIAQLDRVIIIAGAAGEGRLDLVHTLIRRIQTEFLSNTVDSTRRFSKPEVTASDDSNLSIFSLKTSLHGIPVLDSPPSFTTFHTTHNRHPFVLPKYASSWPAINEHPWSSAAYLRFVAGPARIVPVEVGADYRADDWTQQFIDWDEFLSTLGLDDIDLTADLASPSKIKPKKVLYLAQHNLIRQFPDLNRDIVIPDYVYTCPQPPLDYPQYKPPGNDEQLVINTWLGPLGTISPAHTDPYFNLYVQIVGRKTVWLAPPSVNRFMYAFDGDEVYESPNPASNKDNPSMSNTSRVDVFTTMKDEGLFPDFWSNVVPQAISTILEPGDMLFIPPGWWHAMRSEETSFSVSMWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V854</accession>
    <name>A0ABQ8V854_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_889150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF199">
        <property type="entry name" value="MYB-LIKE TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="61"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="61"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="112"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="117"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="357"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4470479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="54033" checksum="5F1BCA1E37A51734" modified="2025-10-08" version="1">MLARQRRAWTLEEDQQLIEAVKREGLKSHKPLNWCNISKNIPNRSNKDCRKRWISTHAGAEVKITKGAWSEEEDDQLRAGVQAFGPRWCRIAQMVPGRNSDQCAKRWKDTLDPAIDRSKWTSEEDELLLKVVNEIGRKWARVVKQYFPGRTGLAAKNRYNCLVNPRRSSLSRDILFPVSAISSPSGEWNASSSSTTPSASTSSPISPISPYYSGSDPTSTLYTSELDLNLSTMIHDALTSASLAQLNDALFDFRTISPVQCENLLLDNFELSLQEQRSGSMLKLYGSSRCCSTARIAVVLHEKQIGYELHPLHPTNSDAQPHIDDNGILLHGCRNICQYLATRYPERGTKLIPDSSDTQATELFGQAKYAENQSFEPFAKNALYETIMKRQQGFLPSDAIGGSALQELSNNIEGYESILGCRKYLAGNEISLVDLYHLPYGEMLCNVGIDVLLTKGPNVSRWWADISSRPSWLTIRNGVPSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V862</accession>
    <name>A0ABQ8V862_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_896986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050659">
        <property type="entry name" value="Peptidase_M24B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46112">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46112:SF2">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="222"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="446" mass="48467" checksum="17222D6D857B4B98" modified="2025-10-08" version="1">MNPLLELIDYHLQRITFLLLACIAWIPLIFGTSLFHVSGLLGGAFPLSKPFSDLANHCKSSQPITAEEFHERQQRLASTLHHLNASAFIAEPGASANYFGNISATAWKLSERPLLLVITPVLVNDTQIEAKVSILTPQFEATRAKMLPIPHDSVEYIEWPEERNPYEVAVSALTIEDKAYLDESARLFIFNGFQKALSNVSVAPSAPEIQELRQRKSDTEIELLKCANEATLLAIRAVHKKMTIGMKESEASRMMSMALKVAGLDNGGCLTLFGENAALPHGSGSDRVLGQSDFALFDCGGSLHGYVSDVTRTVALPKTKVPSEHQAIWGDVLSAQTVAARVAKAGAIAQDVDASARSFLNLTGRGAYFTHRLGHGIGLEGHEEPYIRGGSLDVIKIGHTFSNEPGIYIEGKVGVRLEDCFYINSDGQSIFLTEGIGGQALSPWDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8N5</accession>
    <name>A0ABQ8V8N5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_922500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="176"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="37415" checksum="6B9CCAA1442D92AF" modified="2025-10-08" version="1">MVHVITPPPTDVSRNDIIWLAGPRLIGILFNWSLLGVLTTQVYIYYLNFPKDLKWHKVLVYIVYLLDWAQTCSATYDAFHWFVYGWGSIDALYDLYSTFLNVPILSSVIAAIVQAFFAWRIWRLTQSRIISILIVLLALLQLGGGIAVGIFVWRDSSEVARSDGLVSAVGVRLAGSALADTVIAISMTYFLLRSKSQVMGHMNNVVTRLIRLTIETGTMTAIAAIVDLVFFLKATNGLHQVSGVILCKLYSNSLLVLFNNRMIVTSSKKDQTHFLSNSSGTNTSDEESSREIETFKAAVPRVSTLDLDGGISVSTKGEWRSRSQIEAIPLDDFTRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8U1</accession>
    <name>A0ABQ8V8U1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6697 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_490204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046520">
        <property type="entry name" value="DUF6697"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20411">
        <property type="entry name" value="DUF6697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6697" evidence="3">
        <location>
            <begin position="167"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4480759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="41332" checksum="02B4C910A2B915A1" modified="2025-10-08" version="1">MIPAPNARRELLALPVSTVIIHFLCISVPLLTMPKISSDVVDGIKHENRVPEQPVSFAVMSLSPEYPNQQAHDSSNHADSSNDSSKHGKNEDREASATISVKNSPRGDNPHSTTKVKGEKRSPQTFRLSSVPTILALDPLWVEAVAGFLHDTPSLIINPDPDMNFRIPRALLGQKYKISTGSFQAIVKAHLNPSSTTNNPLVRSILFPFYEENPDLPAKPGDPGIILTKRTDILEVQPATIFINYDGRGKTPSVWLYAGEYALKKCAEMTGEQFSRQPVKTQERWGRTIITLKRDNVWAQMRARIYLRKHNMPLTHENIKTECDKIQAVKGNPGFLDVQDVIDAFIRGDEVGIRAFIPKFGSHLFLSLDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V987</accession>
    <name>A0ABQ8V987_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25986" checksum="2AB4DC8EA54B9752" modified="2025-10-08" version="1">MSPTPTQPFSRTPSPLLPTLTALREVPSPAPESDGEVELDQLAFTIESPSRPQLQLFETVFNTGKPLSGYCQDDPLWPLLAEVASPCSNCVKSPGKCKVLPNSPRCTNCSAKKTCSLGKVLRYRYFARRCSQDIAYSRRFLELHGTPAHQSAWGIPLSTWRQYDAALQAYTSSTSILLELNMLDEKDTAETDQQELQKFLALQQGEAVVTANRKRDHSPSPVAGPSRKKVRAFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9L4</accession>
    <name>A0ABQ8V9L4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">U3 small nucleolar ribonucleoprotein protein IMP4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_841028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF2">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="3">
        <location>
            <begin position="82"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00040513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4482662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="35865" checksum="5266B7FC0A21C953" modified="2025-10-08" version="1">MLRRQSRERRQYVYAKSLEAQERQTYERKQQLKDALATGKSLPTELRKDAKTLGQDLAFDEAQVEPTSHIDNEYSRAGIQDPKIIITTSRDPSSKLLQFSKEIRLIFPNSHRINRGNYVVKELAEACRANDVTDLIVLHEHRGNPDAMIISHFPHGPTIFFTLNNVALRHDIATYKESTVSEQYPHLIFENFTSKLGERIQDILKYLFPVPKEDSKRVMTFANEDDFISFRHHVFVKIPRQVQLAEVGPRFEMKPYEIRQGTIEQAEAEREWVLAHYSRTAKKRSVLSGSGSYSAPRNSRKPPMKKIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9T3</accession>
    <name>A0ABQ8V9T3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_469418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="26"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="19873" checksum="DADDFE7DB0CA9A5F" modified="2025-10-08" version="1">MDKIISKFPRLNEKQIIALGHEDLVCPICFVPLTTLLAEEKTGLAMDSPAYPIEELGITKLAEPFQCNHIFCRRDISRWVKEGHDSCPTCRRPLLARIGDADASANSTSASPAENAYDPSQLANILQHLQGFGIDSFPAFPETQSDASEFFAFLSRPDAHLRRTSHNDDRNEYSAMYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA62</accession>
    <name>A0ABQ8VA62_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N6-L-threonylcarbamoyladenine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_896571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24132">
        <property type="entry name" value="ASKHA_NBD_OSGEP_like_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03722">
        <property type="entry name" value="arch_KAE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="10">
        <location>
            <begin position="44"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="150"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4484011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="363" mass="39800" checksum="56FD844111BED64A" modified="2025-10-08" version="1">MPGKIRKTPLIEAGRDYLALGLEGSANKFGAGIMKHPKDGAATVLSNIRHTYITPPGEGFQPRDTALHHREWALKIINDCLAKAGVSMHEIDCICFTKGPGMGAPLQSVVLVARTLSLLFNKPLVGVNHCVGHIEMGREITGAQNPVVLYVSGGNTQVIAYSRQCYRIFGETLDIAVGNCLDRFARIINLSNDPSPGYNIEQEAKKGKRLLSLPYATKGMDVSLSGILSAVEAYTLDKRFHVQEGAEDKDLITPQDLCFSLQETVFAMLVEITERAMAHIGSKEVLIVGGVGSNERLQQMMGIMAQERQGQVFATDERFCIDNGIMIAQAGLLSYRMGYETPLAKSTCTQRFRTDEVHVTWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAF3</accession>
    <name>A0ABQ8VAF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_714616</name>
        <name evidence="1" type="ORF">C8R41DRAFT_734147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000127">
        <property type="protein sequence ID" value="KAJ4465425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4482639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="120" mass="12934" checksum="4F473139461E763A" modified="2025-10-08" version="1" fragment="single">AKAFAYASGQQFHVYHSTDIRGRGKNQQQITGVAAEAAWRVPVKSAQDLGGRLPLIPGMPVFCTENIATELGLSKGSIGTLVSVTYKEHSSRKYAVSATVDFPGYRGIPVDPAYPKRVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAL3</accession>
    <name>A0ABQ8VAL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="413" mass="46007" checksum="450EC108ABBB7064" modified="2025-10-08" version="1">MHGSRGPGSEATSFFGNIGSVESVVTEFNDNLFVEPEIENDIEIELEEEAVWKEEELRMPESVLEVSRLERVSMTAGLVAPLEDCVGQCDMRSHRSWGEVKLLKEKKTAVLSEVGQPMLEKEARTFYKIVMQSWNEKNSWREITNGTRHVYQSVLNLNVHGGFGGDDDGRTGRKKHVQELHWVHNPLVTSFVQGGGQRLPGCAANSSRDIPNIPHKGSTTLVYAIELSATAIPGSTLSVKCLSVHLDQLTTRENHHQLEYKFLIFASRRFVEIRECRWGWNRDCDGDCGVDCDCEKGDGITSRNKDNGQGRRVCLGRSSGVNEIVILSRAGYEPEEEDESSNEFEAEGSSRFRWLGRGSKSEVGVAPVNRIFFKISHVHRKVADGAPADCALENPITKSIQLAGREGTSFMPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB13</accession>
    <name>A0ABQ8VB13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="22802" checksum="3FC05A10B5A5EBC5" modified="2025-10-08" version="1">MSTSPSSARKFLDNYLVEPFLHALYSASIFAHSASPSTYAQRKGFTADLKKYSTLAWHCSPSLVVGDAIVVWRTCNMWTEHKSLRYLLSTLMLGNLATNIADVLIDITTDAANHEIVMDYVSTSVSFVVNLMSTILIFIKACSRHIRVRRILSLLMESGVTFCFIQAIYVLVQILLYQNKTYSLTLWNLALVMVRNAAAKFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBQ2</accession>
    <name>A0ABQ8VBQ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_838629</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="17031" checksum="43358BAF8BF00CEA" modified="2025-10-08" version="1">MKHNNRTRNALRPEQLKPLVVILNQTIYPSEHNIAKLSNDTGLTQPEIKNWFYNQRRKLRRKASKLDQTLPQLCQEQWRGISQGHFDPFYRGCTCSSYYAPPMQLLEENKTTLPPIAIMFPDIFNDMYDYTLPPHVRPINLSNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCR4</accession>
    <name>A0ABQ8VCR4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SEP-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_842301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01770">
        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="182"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="306"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4480781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="40441" checksum="1C5F0E49D4633BDF" modified="2025-10-08" version="1">MSDNNSNGGRSIGGGANEPLPTGWGQSSSSRRIARIGDISGSSGSSGRSSGGRGSRISTLRELTGTTLPAPAGQGGNVPGAGHGGDDSDDEDNDGEGESWFAGGERSGISVQNPDRPGGRGERDTVPGGNMVRDLLRRAAEGGVPAPVEEASSSFAGGGHRLGSDEVESSYVPDPSQHRVEPTIRHLTFWRDGFAVEDGPLMRYDDPANESILAEIHSGRAPPSLLNVSPGEPVELRVAKRTNEDFVPPKPAAFFGAGHRLGAPVPEISGAGASSSGSTMPGTFADRPSSSVSIRAESNTKFEVDQSKPMTSVQIRLADGTRIVCRMNLTHTVLDLRNFINASRPENLTRPYSIGTTFPNRTLDDFNATIEQAGLKNSVVVQKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCW8</accession>
    <name>A0ABQ8VCW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal calcium binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_981815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.120">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046264341" description="Fungal calcium binding protein domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12035" checksum="7E51CA706FE6F342" modified="2025-10-08" version="1">MRFIVAAVFGYMVIMASARPLPSGLNSEELWERDSSTCDGEAMKTCAIALVPTVAACALAAAQGELDVINDAACIGAAIQLGADFPSSCTACVEKFGKGAESEAEKIVSKLSHIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEQ0</accession>
    <name>A0ABQ8VEQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="51" mass="5891" checksum="91BC741D965C4ADC" modified="2025-10-08" version="1">MYYTYLARRKTLFAWMTIQGALATFVASQYIKPKSQLSALGQAYRMQNATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VER0</accession>
    <name>A0ABQ8VER0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_364612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWI5/SAE3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010760">
        <property type="entry name" value="DNA-repair_Swi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28529">
        <property type="entry name" value="DNA REPAIR PROTEIN SWI5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28529:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN SWI5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07061">
        <property type="entry name" value="Swi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4491753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="83" mass="9551" checksum="301D4AC66EDFF4F0" modified="2025-10-08" version="1">MHARVSQQIQDARITQLEAEVNRLQQELGQDEDAEKIVNKHIKLLHRYNEAKDAAQMLIGRLANLKETTVRQIHNDLDLPIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEX2</accession>
    <name>A0ABQ8VEX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_833300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046684">
        <property type="entry name" value="DUF6554"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20191">
        <property type="entry name" value="DUF6554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="56" mass="6451" checksum="385C5A543EC388A9" modified="2025-10-08" version="1">MCDRDAYHGTSGCHVFGGARIFCYMRPNENPHSASWRPANIRERSMQDPFVRSPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF90</accession>
    <name>A0ABQ8VF90_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/hydrogen exchanger family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_436772</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="8">
        <location>
            <begin position="102"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4486459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="940" mass="100952" checksum="217E35A6F3B3190F" modified="2025-10-08" version="1">MLHQTFLSLYYLRVLRMSRLTCGKLVYISNSIYVLDSGETGAPFCPSFSSPTMGVFKDMVLKRAAAEQAGIFSGSNPSAYNSNDPIVLWIIQVIVIMAMTQLLATIFGRIRQPRVIAEIIGGVFLGPSVMGRIPGFQNAIFPSISLPMLTLTSNIGLVLFLFIIGMEIDGTVIKKNFKASAGVSIAGLVIPLGLGAALGVGVYREFTDPSVNFGYFLLFTAVAVGITAFPVLCRILTELQLLDTTVGVVTLAAGVGNDVVGWILLALTVALVNASSGLVALWVLLTAVGYVFFLLYPVKWGYRWLARKTGSLEQGTPSTVMMTVTILLVFISAFFTDIIGIHPIFGGFLAGIIIPHTNGYGIALTEKIEDIVVILLLPLYFALSGLKTNLGLLNDGITWGYTILIIVVAFSAKFFACAAAAKVAGFNARESGAIGSLMSCKGLVELIVLNIGLDANILSTRTFSMFVVHAIILTFITTPLVLLFYPAKHRSRIVIEDLGSNIIASSDPSTEGDELTNKFALVLDQIDQLPAAMIVTRLLCPTITCTDSKAEIFAPSLDEKSLPIIPYQVSLPITPLSSPISLTLLRLIELSNRTSAVLKSHLAHTDPVVSVFKTFACLLGGGLKVLKLKVDIDVSPREEFTAVIKDRVRENSTGMIVIPWASGSHSTDAEESEIHGVRNPFDSVFTSSESKDQIMSSVLYSEFIRNIFLTAPCDVSLFVDRGPSGTSTTSGVGPDSLLVLPFLGGPDDRLALKMLVKICAGHEDVRAIAVRVSRGTQDENEEEFDKKHAAEVFLHNTIAGADTVYGNLNTQTRLASDTADNLIWERYASSFAAERNPSLSSALSRITFETIQSSKPLHSVVDFFSGKQVQSTGRTVVAVLGRSRRMAVERLDGELRSIMSQRNAAMGSTVKKALGDVGAALVATGADASLLVVQTCVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFJ8</accession>
    <name>A0ABQ8VFJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_343742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118:SF12">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="224" mass="24748" checksum="406240BA81B6D83C" modified="2025-10-08" version="1">MNRKREFIDLSHPLDPNNISLWRTMPPFTCCPIATIEKDTFSIHTISMGTHTGTHVDAPCHFIQGGKSIDEIPIDVLHGPALLIDLTHKRAHESISWAEDLSPYAEQMQPGVILLLLTGWSRYWAKEGQEYFKHPYVEPSVAGKLLEHGIMVIGLDTPNPDVTGSGGHPFHEIFLGGGGYIVENLTNLEKLGSMKLMVNLLPINIVGSDGAPVRGVAWDEPEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFQ5</accession>
    <name>A0ABQ8VFQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_831632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="67" mass="7413" checksum="40AC06B81EF1F3BB" modified="2025-10-08" version="1">MDSRSNPSSHSRFLPLSYVAHIRTGASAHESELRISSTLRFYSGFGIPGFQTRHRGSHEAEGQALIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFV8</accession>
    <name>A0ABQ8VFV8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_921131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4486962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26206" checksum="94263A0F91F92E65" modified="2025-10-08" version="1">MSHSHSHAPGESHSHSHGPPQPQPLPTADPALLAVIEADFRPISVIVAADNTTLLCEPHKQEKCPTCNLDYVHLNRLSKILAQNPNLKAPPPGNVISKNLSQAVNNTKEEGNAFYKMHKHKEALGRYTMAASIAVQRPPWESNQLMREELSTVLSNRSASYFESEDYISALADAETVIAIRRNWSKGHFRKARSLVGLGKLDEAVEALQVGLAFEPNNAELGAYLEDIQKMSKEGQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFW1</accession>
    <name>A0ABQ8VFW1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="839"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="968" mass="108297" checksum="2E31F85871DA552D" modified="2025-10-08" version="1">MPLTQFSFTTQFKKDRTTVVRLPSLSSMVNTGAVVPIVTPQFIPDRRKSVNVLMGPPPIPTPMPQTSRTSALDMGMNSGSVSVSGPVRILRLSAIPEVSLPQALPLPPAFPPTLRLSIRASVILRKTITIESSNEEPRDIIVHVDESSRAELRGRPVVVDGAFAILDSLQMWIWDGPAGRWNEINFGDDRILAGKTYYLSLYRGLSGGMEPEWFHYHNLMESHLELQTEIEHLYATLEEMQSSSEAFNTNTIALVKATQQSLSQMVVHTHNLVAYVNGFKMDFSLKLESNLRQTQLHSSNPRKDISQNRDRIHLILTHLQARSDQTASAPNSVTQAIAAIHSKEPVIPPNASRMTEDTLQILHFLWLCQEVTKNLSSGEGCKAVLFHPVWMPSTPRSTPLSLSQSRWSYSFPPTQEFQIPGSLDDFTKDQLMTLFRKFKNQRVAEVSDIIIECQQQRRKIAEDTRERNLLLQRREVHHKNAYSQIDAQAVTMIESLNRKLGEVEERIHLNAESTASLAVKQLWSQTQNFSDLWSTLLRHLLANSDHMQNASTRIQLAKETLEALQPQPRGVFKNHEPCLEEGTNTGTPVRHPHGCTKECDINSIPVIFSKEVGQQVADNGNSKSHHGLNSGYPDEVTASNDISNWELVSRESPNVLCLMEELRIQDWRNVVHCGETPVNTLSLEHLGECLEVISGLFQISQISDTSEDNHAQENCTTPLVIPEIVQVCSDNENLTTSVSKGALQDGGIESSEACDLVSEVGVSQSALVFENSGPQINEEVSPCEPEHSSKEIEDENLDQELPDVSCGLDAAVKPIYDMDSGQTPLITRSYPIKRKMSRLKYLVIVFLLLCGIFLLLEVMKTTVEQWFEEVEAFGRLNEQRHKLHNMLNARTINTHPKRGRGLYIDMWSGGRAGFSQFLRETKADALLLGAVRRPLALDQIRRDASQQQWTEQLDAGFSTGAMGAVGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG22</accession>
    <name>A0ABQ8VG22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="52254" checksum="D774390E3F3E4B30" modified="2025-10-08" version="1">MPKRKEAPSSESSGQEEESNSSNSDSDIPSARKPSAYSSLKALALRNLALGSGKGQSSLRSAAEAESNSGYKNQKNRSSSSGSSSASHVPTKKRKPSSSKRAVTPATKPSKTKSAKEQKMSVLGKTEDALHFGAIAIIPEPITNPSTDKLGPIPYLDLSSPEDAGMFDDMRLRKLRTHKTAVIDRIDGFYVQRSWTHSELMDYVTKLLPIPMRYLSLSGRWVNPFYDRKDPDSNPEFFGPLTLCIISRARVSSVTEDLASWPNGEYVYQLSMSPRRNTWRDNVLIFAPRVSLADPMVKWARNENPIPAPRPLSDDENFPSAITSINEEGRYGKSGVKEAEAIQAKRRRPIRTYKGKGKARAASSSSAGELSDSENRGADSDEYPGMKEAISESLATTRSQSTFIQQASQSASTSQAPAFVYVNDLDDSMNIQETITASLEPTTPPVHVPTSPSIMNLSFVNDTIDSNAFTAAFNDFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGB6</accession>
    <name>A0ABQ8VGB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_324538</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4493296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="183" mass="21000" checksum="7629AD6C14EE1A32" modified="2025-10-08" version="1">MSVIRSFKASDMFKFNNVNLDVWTETYNIGFYLHYLSRWPDLCCVQEAPSGRMMGYVIGKAEGQGSEWHGHVTAITVAPEYRRLSLARKMMSLLELVSDETYRGFFVDLYVRCNNLVAIDMYEGMGYSVYRRVREYYGNLGVGKGGRDEEDAFDMRKPLSRDSARRSVRSNGRDIVVSAHDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGB8</accession>
    <name>A0ABQ8VGB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052998">
        <property type="entry name" value="Hetero-Diels-Alderase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060:SF1">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045317487" description="SMP-30/Gluconolactonase/LRE-like region domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="37864" checksum="15F843F2045D651F" modified="2025-10-08" version="1">MRLNFLSALLLSILTSSLCDEHVTRNEKRSVVVETIHRFVPNLNISLENLAIRQTGEIIVTFDSEPTIYQIEPEVNGTGTFIYTFEGYTDLHGIVEVQPDQFYVTAGNLSLVTHIDVLGSCSVFHVNMTRFPDYVEVNKVADFPNSRILNGMALLSKEEGSVYIADSRVGIVNILNVNTGENFVAINNWLTNQPPGASEISNCVHGVHVVQLTPNSQKYLYFSNYAQGIIGRVPIHDSGLASGAAEVVAGNLTTPEDFILDTKGNIFLALFQANQFIRIDAHTHEITVLAGSPDSSEYKWAAAVEFGRRESDKDSLYATINGGYLESDNVGGALFRIRGGDIAMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGV2</accession>
    <name>A0ABQ8VGV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_836040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="718"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="737" mass="79597" checksum="A92773236903B315" modified="2025-10-08" version="1">MVDKRENDEKRRKKNDGEPGLDAGYFTGYETDATSTRTKLKKKKTKMKKVSGDGYETDDGSSHPPLRKSKSKSRFFKLGNRSKPNVDEDESTQAPAEVPPPPPPLPAPAFRLPIAAMFATTLNLNVENAVLEPPIGPLGFSRPQSPAVASMSPSLASSESATILQNQKNGYDVESLVGVHEPSIIAVNTTSNNSPNKRTIIRFASDSSDNHGTTSSSNGHSFLSRLTNVSSSSASTTGSMTSPNLKSLNISYPLTRSPSPPSPPFNTQPMVAPTSGLDRSNTKRAPRPLFLNRIPSSQKKSTSNSSDNSPSDWSPAGSPFVVLTPNPASSLASGGRPGMTSATSGSTNSANTVTRLHIPSPLPLRARDLSPAGSYRDIMPSTDFIVPSPSNDVFVPPNSLGHYDIPPPSPPPTVPLPDVPTNPEQWRGRGQGSEAGHQPHLAVDPSIRSSSPSNPPQRGRVSPFPTRPVQSNGIATVHTVPSRGFESRVRVNRYRGIYAMPPPAGGWKNNFSKDSGYASSPETSSSKRHTRKSTNVGIHIEQPSDSEDDPGSDADLRNVIQGFTDGGRSASATGHERDVEPEAALDRRRSLEALQNYYNSYDIGSRKKSPSRQISPRPSFSRSASEEDLSDDRSRYTSDDKHSMYKTNNASQARSLASGWADDHRWSMSVDGESRASFMDAEKSDEARERFIRRIEGMFDQNGRELPPNLGTGRNAIIPPVPKLPQGLQGSSSKTWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH10</accession>
    <name>A0ABQ8VH10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_895592</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="6">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="35303" checksum="BFFD4AF7C2F6171E" modified="2025-10-08" version="1">MAPFNPEKWIEQLRQCQHLPEESMKTLCDRVRSLLMEESTIRPVCSPVTICGDIHGQFWDLLELLRKGGDVPETSYIFMGDFVDRGHYSLETVSMLLVLKAHWPDKVTLLRGNHESRQITQVYGFYDECQQKYGSATVWKACCSVFDYLNLAAIIDGTTLCVHGGLSPDIRTLDQIRVLSRAQEIPHEGPFCDLMWSDPEELMENWAVSPRGAGWLFGGGVTREFNHVNGLSLIARAHQLVQEGFKYMFDEQLVTVWSAPNYCYRCGNLASIMTVHESGERTFEVYGPAEENARDKGMQTRRMNMPYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHG9</accession>
    <name>A0ABQ8VHG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_415637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="698" mass="74665" checksum="87CA6E3DCF0FF02B" modified="2025-10-08" version="1">MCRNVSSPIFDVPEFPTLRRVKPLPKRRRTSSTHLSILDSGTINNTDSDLENMPRMLVAETNGVPHSLHMPGLPPIPLSLPGPDVTAEELLAHADALQSYYFPILDAAAANINAVADGFANAAEPGYIHPGSDILSDLEPGDLASSPGVGLVGLGLNNLSLRDRDDSDRGDGDYIDQPGNAKKRKVPANTSHLRGARDATSDEEVEDRDGTLMIGIPTGTFEAGANDSDTGQGDGGGEGAGEGGKSSMSTIRRLLGRRKTRLSAVTLAGLQHKETLKVRKRQLAAVLGALSLGDTLALDQALSSNSAYPFSSSSSAPDDALIPSVMGASDAALPVGGKPSLKIRLSKRTGPRMARSILSRLKEDEESHVQVPESDFTFVCYSATADRLSATKKEVATLRRRFEDELARQASNAASLAAATRAVASPLSSRSSRQKRSGKARTDNKLRNQPPEFLDPALNGQTYGAGGIQNSSGNVSSSNAKSSRNGKKKKRSALANASNPHHLRNYVPSRLPYTAGGCPPNANGTNQANGNDLSPFPIRFLSAEIPPRRSNRSKRSQAQEQQQSSTSLTNPADEWLCVFCEYELFFGEEGDYRKALRRRKTVLKRRRRARERAAAAARGQSKWSTAKKSQQPAPVAATHDSEEEGDDEDNYGDDAGYEPMGTGGQTVGNGVNGMLPKKTKWRGDNREKGAGEAKSSYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIA8</accession>
    <name>A0ABQ8VIA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_827745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="70" mass="7969" checksum="0861FF4229F2B82B" modified="2025-10-08" version="1">MIDAQFRVSITSFSLREENAFPLQYLPRASVTCGCCISRTSLAVSLDMNFIEDPYQSHINKKLLLTSIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIB5</accession>
    <name>A0ABQ8VIB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_762888</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="3"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="20318" checksum="59C0E7677CECCD62" modified="2025-10-08" version="1">MGLQEYQIVGRHLPTESDPTPKIYRMRIFATNEVVAKSRFWYFLRQLKKVKKANGEIIGVNVIHEKKPLKVKNFGIWLRYDSRSGTHNMYKEYRELTRADAVKSMYQDMAARHRARFRSIHILRVVEIEKTEDVRRPYIKQLMVPKLRFPLPHRVSKFKSTFVAHRPSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIP8</accession>
    <name>A0ABQ8VIP8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_826936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="387" mass="42442" checksum="EAAC8FB776C709D0" modified="2025-10-08" version="1">MTLPPRLLLRASEEVVSGICHVPLTCFWTFSFTSSFSVALSSYHPLRRLSELNSIEMVTVPVVALSDPRSNVSPASTPSPPPNPPITTEEVDVDELASTVEDPPLGQLTLFKSVFGVGVSLARYIVDDPLWPILAAAGLPCSFCVRSKKSGSCSVVPHLARCSNCDDKKPCVLGRLARFRYFARRCSRDLSFARRFLEAHGDPGQRTRFSLLPEQWRAIADKIESSTSSARALLELSPLDDQDRLEEDQLELQDFIHRQPKLPAVSEPVPSGTPPPVVPDKVLSVPKKRKRAVRMGEASSSKRKRFVEQDLGAGDAEYRRVVLVLPPQVMSRPEVLEPPTPSRRGAPHTASHPLPSPGVLLRIPGTPSSPPTLLLWSPHPSSPKSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ40</accession>
    <name>A0ABQ8VJ40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_829098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="20896" checksum="2AEAB4DF4886D3CA" modified="2025-10-08" version="1">MHIPDEEIYNPCPRPNPAKSRIKPEDLPKCSTEKTLPEEYHFNVRRWRLEPGYIKPRKLFYGFGVDIQDFIDYHQRHQLPRPPPMDNRASLWHYIMDDVMEDLSARCRFKLQRILPLSPKYDYTIALYNSHHLSVTELEDDEEEDVIRIMKERFGDVVAAQRPQWFCLLEDSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ51</accession>
    <name>A0ABQ8VJ51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_980970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="57094" checksum="84474BD58399CC83" modified="2025-10-08" version="1">MEQPVPLPRELSDLIPTDIYELIISFLNHDPVTLKFCSLTCKSWLWLSWKTLFQSRTIHIHRKNIDDFLKLINLNAHTITIIRFVQHLHIEQGGSKRLPVSWQLPWGIQESGDYEIFQFDDFLHLFIGLTAVRTLKLGWIRCDTSKSTSDALRSNFGSVTTLDLDSVILSSSDHFFDILGAFPLLSSLSLTGVLFNGGRLYDGLDNWDELDARRTVLKYTPPPPSGLHELYTNVTEDVSEFLFSWMTYHDIPLPMRSLSTGLFSESSNAALSKFLFHSGSTLENIMIRDAHESTALDLSPCVNLRTLEIGCVDLQSSSLDERELGSETFVTNILRTVASDNVEYLKIVLAISGYEDAHVQIHAFDWRGLISILEQSQFEDILVEISVSGYETDVEQALSEVVRFFLEICLIFTVVTTIQAFPTTSSLHGPTARSPTVFRGRSYKNPRQDFDTCPRDILLNKAILGRAQRFKSTQKKRDEVLLRAVARDEGTHIALADEHVSTSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK75</accession>
    <name>A0ABQ8VK75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_918083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="325" mass="36279" checksum="3A4524A101E8991A" modified="2025-10-08" version="1">MSSADTTYQELWITRCQIPSPQYCGEVDTDSGYRYHAEVSTNDRLNLEDMSVDCHSSSDNHSPYFSPTVSYQASNSTGHQYLNSNVKPVPRLDTGIVDDMGHRHNSLSASTTSWSPSPSNMSIDTEVLYLRSQQYESPQSSTQFESSFINGFPCHCGTGPDDNDGRHLSEPDAFYLDNMIHSDPNALTRTTVSPQILGLSFEQELTPLNFFNDPVLIPQGKTQVATERVLAASRRRRGQLKPGGKLLHCHMCEATFTAKHNLTSKKPISQVFMIPQSIISQITLIHTGERGRIPVSATAHLAPNTYSKDIKRRAGYLRKTRIFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK77</accession>
    <name>A0ABQ8VK77_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_830019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="175" mass="19490" checksum="BC6F7E587D3C4467" modified="2025-10-08" version="1">MLSPNPVVKLESSSLYISTTQIFARHGAFHWIIYVTDADGKASTYQWSEQGGTPGLQAEGVDIQELHPVTTYSSTNNLTLAFFKITGFDPATPSDKIRQAALVAFPDRGYPSVRESRQNNLTCRTWALKVLRILMDGGWLVRTDIPEVIEDIVKKRSIEVEGNLESFTESVVVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKB8</accession>
    <name>A0ABQ8VKB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="25"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="269" mass="30420" checksum="15D753BF702D2BB5" modified="2025-10-08" version="1">MSSDDALVIALGYDLLAEKRYWIGITALWVYEYFLTVGDEIRYIWKAPKDNIVFCLFVLNRYLALIIITVTCVAFFSSYWTEEMFVPMVPLCLRYGYAEQLETLVMCTIAEMLVLLRVYALSGNNRTVIICAIPLIISQWGLLFYVCSQSANGTANLTLLLGPSDVTTLPDIDAFRLCISVPPLDVVPYGQAYLCLLIAYDGLTVLAILYIVAGQSDNLHLMPILKLIQRDGLLYFAVMFTSHFVWLMLTLYAPTGLQFIHNQCVIFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKD0</accession>
    <name>A0ABQ8VKD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_763367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046143192" evidence="2">
        <location>
            <begin position="31"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="661" mass="67883" checksum="2A3A868B45DA47B8" modified="2025-10-08" version="1">MRFSNVTHRRCNTVMDILLILTLTATTTSALPLRFRRDSDSSSKSVGTVQNYMQTALQTYLAAQNGVSNFHAISDGWKPIDFAGTGTSLNGDEAANSIFYIADQIQGATTTISYSGMAISFIQDVNVAMSLNTSGASNPEVTKAMQASSKACYAGMAATTTTVSKEYAEQHSGQAPNITSPEFLQFAAQDPEYTQASAICQSATNTYQSALSRAVGDDFYIFSGALNNIEQLTASVTFIDGLNMEVSSETAVAGKGAGKYKPYYAIPTLNGTMSAWQSNSNGFSSSPAFTWSSSSSTGSSTNTTTSGGGGIGFIWEDFSGSGAGSSSSSKTTSNVSSVGMSVSFGQISMFGVEYGLWNTPEVAEALQNPPDAITKKGAPVFQKYYGSASKPGPLASWKDQALVVYQPSFSVEFSSADEASSFHQSAASAGVCILFICIGGSGSSSTSTMNYTTGSKFVTYNDTTNQAYLVGFTQTNFFPNQGPQDDSNWPSLMGNNTDATSATSDTDSSSNSSGNSTTSDGNSTGDSSSNTDSSSTSTGDSTSDADSTSSTDSSSSSTDASSVDNASTTKNNGTSSDSSSSADASSTTSTSDSPSSAIGSKGDSASSTSTSGSASANPKSTSGSGDDNESTTSETKPSMKTASVTQSQTKATPVVKASKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL28</accession>
    <name>A0ABQ8VL28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="349" mass="38874" checksum="51610F46AA67C1DB" modified="2025-10-08" version="1">MPAFKYNVAYNPIGTTLIAFPSLESVDDKLLRALHQTSNGSHNPAILSMNESKQAPSSSLPPNQNHVASTQHAPHAPSLRSEGVEAESSFVQETNAFRVALQHHAQHMFDWGSLELDGFRIHQSRDANHEGRTVAINNIKAAGIAHVLGSNYPEHFDDGYIDLLISRADQGSAWNDEAQAKTTRSTHPGAGPLAFHTPPSSLEYDVDPYALPRSRKVKNKDIWTHWFMFRTDQDIDYPPLRPARFPTLEDHTLFIHVNTKTQQKLQTISLETNGAPGGPPIISRCLQIWIWKAGDHEWRTIQYGDAEVIGGESLVLSLCKGGLEPCWVLASSLRKKGYKFLLQKTTHVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL30</accession>
    <name>A0ABQ8VL30_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipase D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_895092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF186">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="708" mass="79836" checksum="9DD3DD017A1530DC" modified="2025-10-08" version="1">MGDHVAVEKLDGLEVLNEDSVSFNGGIGLVRGRQKENESSAHSTDDFLEYLLGLRRQGFECIVSSVRRSRPYKHDCFLNPNRRRDDPEEKAADALRAEINASNRFDSFGRRTFRKRPLSFICAPPAKHSEWSLDKVLKRKAQQGVKVYVVVYKEVSQTMSMSSKHAKTALEQLNPPGTHYIQCMRHPEHIGAEKTVEFWSHHEKVVVVDNHRLCDTHNHPLADVHLSSHALIRVSQDYNNARVICPVCRGLCQQLTKHSGERKMPWHDVHMSPSGPVVLDIKRKYLPLTRVPSQQNAPNESIARYPHREVWHVMGRKCEQRWHDWLGGQGQNQDPSNDETISATKKGDVVTNEIAGALAHRIVVVIPEVPAFSGNVKDESSFKIIMAAQYRTITINWGGASIYETIRKAGYELMDYIRFCHLRAYDRINAPQHSGVSLHQAQVALARKWLGSQVTSATDSCQITKEGVVITEKTPVREEAVAVPDTEEEEEAKQIIRRFERAAEAVRGDEDVSDNVVQHILSDKTGLEQYKWLGMGSANLNDRSQKRDGDSEIAAPYMASRFAASLKRQMCKKHLGLIPPQDDDMYDDHPIPYMRSAPHPNPDRLNSQEDQMVAAPLSTNPIKLWTGIARQNREIFTEVFRPVPSNLVGIGQGMIDMYPKTKTGHVVPGIPLQRVKDRLSKVKGALVEAPIDFLIDDKGFVEGPDWAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL95</accession>
    <name>A0ABQ8VL95_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycopeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_979863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047402362" description="Glycopeptide" evidence="2">
        <location>
            <begin position="24"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27219" checksum="5F468B9EF0980A6F" modified="2025-10-08" version="1">MSLTLFSAFLFFVLLVSPAFVDAETHIVKFDNQCGYGTPQLIQGNDVLTTTEYTFNEPYSGIAYLQTGGCGFNGEYCGIVEMTLDNPTASGGGASADISYIPPLAYSVPYKFEFYGGCDGEGASCNSSACSEAFYEPDQTYVQVACQNDDVNILITFCEGGESNTSIGTGSTAVDVMLTSTTSSTSSAQVGMSSNVSPTTVVNGNSATPSVFSTTATAPFISSGSSSRRCNDNRRRRSSNLSESLKGHRRRSPLSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLC1</accession>
    <name>A0ABQ8VLC1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotide-diphospho-sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_881465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="413" mass="48180" checksum="E1D96E5376790E2D" modified="2025-10-08" version="1">MVSYSPLFSSSPARWKQLVLSKRITIASILLLFSLLALSEVFLERGISTRILSSLSFDAKSLDQSPLSCSNPFDPSSFPHHTPRPTYTRKANATFLTLARNSDLAGVIHSMKQIEGRFNRDRHYPWVFLNDEPFTEEFTRCTSAVTSAKTHYGQIPREQWVQPDFIDEEKATKARKALSKIKGVFYADSVSYRNMCRFYSGFFYKQPLLQDFKYYWRVEPDINYRCEIEYDPFLYMEDNNKVYGFTISVPEQQETTPTLWDTSMEFFNQNPQYLHPNNAMRFASKDGGQTWTRCTYWTNFEIGDLDFFRGSEGYNRYFEHLEAAGGFYYERWGDAPMHGIAISLLLDRDRIHHFDDIAYEHTGWEQCPNPVSSAYERGRCDCDYDNSMDVKWKRYSCQADFEAALAVPRIHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLZ1</accession>
    <name>A0ABQ8VLZ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_295143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="54"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="266"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="458" mass="49205" checksum="7CF2C4F5762D0C67" modified="2025-10-08" version="1">MSSVVADYALLPSDTRNDADDSSNDLGFYENDAERTGKFAAFLAQLSNLFHRNVGLLLIVTAQAFLALVNVAVKKLNMIDPPVPTFELIFIRMATTYVFSIAYMKYTAVESPFLGPKGVRFLLMFRGFSGFFGVFGIYFSLKFLSLSDATVLTFLSPLCTAVAGALFLGETVGRKEIFAGLFSLIGVIFIARPTSLFGHHGPSLDGTALSMNSTNASSVFIHGMSVKNATSFLNSTLNDLHPTETITSPSATPTQRLIAVGVSLLGVLGSTGAYTSIRAIGKRAHALHSMVAFSGYSVIVSAIGLAVTHTPVVIPTSPIWLLLLLEIGVFGFCAQIFLTLGLQRETASRGTLAIYTLIVFTSLLDRIFFHSAPSLLSVLGTLIIVGSALWVIVTKKNQNQKSLPIKGVVDEDLPEDEAGEEEILLKTVEEAIGRESASNSNHDVFEVVVQNETGSPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMP5</accession>
    <name>A0ABQ8VMP5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_902147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1102" mass="119188" checksum="D2215AC52DE7DCCD" modified="2025-10-08" version="1">MTGTHLPINQHAVHQIHARIMSNVVIGPGGQATLVAPTQPESSNAIVSSMTVINTASATPQAVFTSPSTATSDISLTSILSSSSATPATPTTSGLVEVSTTVVVTSEVVETSTTSSSNPTTSNASSDLESATPTTSVDLSTTSLATIPPTTSVDSTTASLASTSTSEASTNLLSTLSSSSSTTASPSSLAAATTSSATNTSATKESTLYIGIVLGTIIVIACFAALIAWWFRLRTHNRRRKKSVVVPWANRPESSLSSFTDSDSLEKGEPPNPHRHTWEPRGDRDAGEPKRTKSYLEDIGSPVKRQSLPILSLPSPLPAIYPFRDHSLPQYPASSSSSFPSVSLLSVEPLQESVAYPLPNSSGSRFAMNLHPNPSSVHMQFLTDPEFGTPRESKIKPRYLSLNEGLEVPWNTEAPALALATSYPLPVPSGNVPSSSASLSEEHPQAQEITPFTDVPASVSPSQAGTWSSTFRANLLSAFNAVAKAAGGIRLEEEYDKLSPLPSRSASRNCKNVLRREKGTSGAPVPEPVWVEYFGGELVGKAPTLITSTPLEVTQADEGIGTDHVRTSFSRDGLLPFPGTIDPASTKLGLAFGTGMGLESYRGNDNAFSSLPPAQRSMTPSRQISNTSYTSTAALVVKKKSRSTGTTRSSTNVHSRISGSQRRPRYAYGGEMAAVAVNGIITFENVDYEVDEVDAIDTDKQGRKGEEGVDREAEESECSMKLSTLRIRSILLRLVVQSDMFKLPTSIYFSLFIFGSSYLVSSISPACAAPLPGNASPVIYNITSLSNSVDSSNEYGLTSVTQIIDRRSKGNLNPVEKMWGQGGYNLYRNWMTSFFPEELTRKDIAKYFGEFHYNENINYASRSGLRIPLAGGDFTEYLGVNLATGESGNRGNYNAGVYKYTGRPYRGNHPNDLVVKVISRARGGGGPDIHAYGEAMALDLVGQYVDSGKVPWTTMTKETNRRTGTFRIVPQDFELYAIIMKRVEGAPIEETPEWKGASSKARNRMMAHMKDLIKPQVMDLWSRCKLIDAYGSFLGARKDLISPSIRSDINRNNIHVVFDRSGRITSARLFDFGYPGIISVRPETRRQDIEVWFDQCWKFFWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNK0</accession>
    <name>A0ABQ8VNK0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAP2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_917821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF35">
        <property type="entry name" value="RE23632P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="104"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="331" mass="37354" checksum="4C499597EF8C70C8" modified="2025-10-08" version="1">MYNHRRERKPPVSATRKRKLLLSYAPDWIITILLGVLFFLLDRIHGFWRDFSVDDTSLRHPYAVHERVPTFALVLICFVAPLLIQPVINLLSIRSWWDFHNATLGLILSLAMAGVVTQFTKVTVGRPRPDVIDRCQPPSGTIDPTFGLSTAAICTQTDLSLLKDGFRSFPSGHSSLSFAGLGFLAFYVAGKLHLFDHKGHIGKVWLFLAPFSGAALVAISRTMDYRRKYHWQDVFIGSILGTVMAYFSYRQYYPSLSSELCHQPYSPRIAREPEVLPLHHRHQHSETSALPPRTSAPDGTVPRPDPGSLTELWGNNARVETSEYHSESQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPS8</accession>
    <name>A0ABQ8VPS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L16p/L10e-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_790686</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_uL16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="23575" checksum="3DFAC938AB54F88F" modified="2025-10-08" version="1">MFSLSRLFRPSFTQTRLRSQLAPRQVKYIKRHKGVIPIPIGGSTSGTTLTSSAQWGIRIKSTGVRLTAKQLTTAEDVIKRKLKDVVKGGKVWLRVFPDIPVCIKGNETRMGKGKGTFEFWATRVPVGRVIFEIGGKDIREELARDILRQAASKLPTKMEFISRDTPPRLGNLVLYPPKPVKRIAEESVPSVDHGQIAGALATQPTTSSKTTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ22</accession>
    <name>A0ABQ8VQ22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_864676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="257"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="705" mass="80378" checksum="FD5F4773A3D0EFC3" modified="2025-10-08" version="1">MDGPSSNTRKRRSSSAMEIDMSQSSFKSDVTMEESVATIRGGSLMQIEEAPDIDAETTSRGAKIRVLSAIEMDPRHRRRIHDLEDVLARKDRELQSLASDIKSKNSFVTVLEANIADLKMDIEDAHQHFKVQNSGAWAKVDELDMSHKKLLQKNVELISRVYNQDHELDKLQEHLSTQTAELDRIRNTSEENSTAQNLELECHNLKLQLDALSQSNSSLSSTNTGLRISKVWLKRKDEGVTRLNAEKESIDLVAQEKTEMGDKLSRVSEEIKQLEDNNSELTSEASNMQTKLHEAETEKNALEEDNQQLLNDFSVLKEDHDTLKVWFNILSPLNHQEVTNAQDSLRINFDNLLTTHTSLKEQAEAKIEQMQRALSKLEKSNEESLDDEDEADQGGIYPLDREDAAETNDSRVQEVWQKKGFEEYDPRFNVWRIWTIFARDGISQERQELHIKDPVKYGPKLRNTRIDKFAPDTKTMKKSPCNRALIHHFAAKAGEIAAQYFQASCQSAASAWRNPRSSRFVPGCYANNERKTRNAKKWTSHSDIATLVIKECRKRGDQEGVVFWSHALLITETIEDAGESEEEDGVIDVEIEGITMKQNVKKVSRLYWQEPVIEELYKMVDSAPGMETAIFHQAGAPRIPRIHTDKIDHRPPPLGLPQSVFCKEYLAALMPHELAELKLADHDIKMYDFGGFDPNEHNNEAMDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ72</accession>
    <name>A0ABQ8VQ72_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_258907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="485" mass="53310" checksum="627529CC7B382935" modified="2025-10-08" version="1">MTDCGRPDFCDSASATSSSLVITPASGHDISEPHTQSGFIVHRIQKPKNVDLSNSPQQLRLQQLPPYLRSIMYQPQSTGKGPIQPHVSNLPRRKPRQRSVGAFPKGSPTLATLDAVKALSSASIRTNAARSPTPPRSSSSSFSGSQPRGPEAYFIDDEPSPSVAPIYIKPSAPAFELGHVIPQSKGHIQPHITNMPRRRPRRPRSLLSRIETSTQQRKLRDRERWEKARCLQEVVKGSEIWVAFWDWENTSEESDDEDQSDDSLAEELLRADRVIQIISREQEDQMDSIASTGGVEDALKNDLKLFLSPRVVRVRDDGIPHTSLEQMSLARAFLSNVLPRRTDNLARTSSVPPSPRTASTPSLSRSSSSSASPFPSSYSLTPPSTSAESRSNKRLLITVPSQEYAVDALAIVVIAFTLLGDITFLTTSADEKESSVSPILEFLIRLNDLEELHPHWRGALSCDGIDWLDGVLGSIMSSGGPNLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQH9</accession>
    <name>A0ABQ8VQH9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_901154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="32260" checksum="77BC4DBE8467F595" modified="2025-10-08" version="1">MTIYIAPALLIGLSARLLMDFLSRSEEQTVRDFLMAGLWQGVLWCTVKNHVLSMPVALGILAKLFVDYTFMSDALKFGITLVGVALGAIGTDFLSSVVDNPKLDKDKRKKTHSTKDSAQTRIRSSRHADKPSSKARSRRTTSDITSVDSESELIGPRASMSPLDRQVAALRARASLADSERRRFKEERKWAKAQGNTTLAAQLRWQVKRYSALMKSFHREADTKLLEAASGSKSRLQTIDEHQPIASTSNDRSERRRRESTHRFEHSIVHVEIDPSKVKSAIRVNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQP4</accession>
    <name>A0ABQ8VQP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_237446</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046739448" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="23"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4496930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="239" mass="25131" checksum="B8968CB7B9A32F5D" modified="2025-10-08" version="1">MSFSRLALFSVIALRAIHVGLAHYTFPDLIVNGTVTSDWQYVRETANHYTNDPVTDVTSDAIRCYELDSTSAGAAGIATVAAGSTVGFQPNIDLYHPGYLSAYMSPAVPAANSNSAGLNSTWFKIWEANPQYSAATGMTFPTQNEVQFTFTIPKSTPSGQYLLRGEQIALHVASTVGGAQFYIGCAQINVVDGGDGTPGPTVAFPGAYSATDPGILINIYALPAGYTGYQAPGPAVWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRK9</accession>
    <name>A0ABQ8VRK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_235764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="32106" checksum="393451CB1A45483F" modified="2025-10-08" version="1">MSLFDLTQLPDDILFHVCNFLSSPGILELRKTCKRLHALTLERTIWTNAYRNFGYFLPPGPSASQTVHELERVLLHAHQWDTIWAIPALLRTRDHRSLKISVPKIRSLALYQAEKEIYRRKIQTKPFWLQCRNDITDSSANLYIPFGRESGNNTTSLQLCICKVDSLGNTTFDDIPGVEITYDCIASVGYDFFVTSQHSGETVLLHIPSQKIYIINAASGTSTQEGHITNVIFMPKYVLLVYTHYGKRARVCFQRIAEISPCTFRKLRSFLMMHPSMAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRL6</accession>
    <name>A0ABQ8VRL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gti1/Pac2 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_758324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF1">
        <property type="entry name" value="CAMP INDEPENDENT REGULATORY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="273" mass="30434" checksum="E0262F0B523E76EA" modified="2025-10-08" version="1">MQQATHPRLHVRDARDAHAVFEAVRQGLLRPAVRRLNEVERSMHVRSGSVFVWEECDDESGLKRWTDGRVWGQSRMREPYLFYDEKLPSDGGSPEQSQRHPNFRFVEGPTRVTHTSSALLHQDRSGGTHTGLIKQAYSAWVTLSPNSKPRKWHLTAYFTYSDLPSIPTIDRDPILSKIAVPSGIYHGGKTRSKSEDDGAYSAVNPPSSRPKTPAIQSSTVHGSASATSSASLPSFHSTVGPYALNPRSAYPQTGSRMSEDHRVIHMLNSRHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS24</accession>
    <name>A0ABQ8VS24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_755328</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="36583" checksum="7C73203D811E4614" modified="2025-10-08" version="1">MTPKLVLVTGATGRQGSSLIHALRPAESEAHSGEHEFHILALTRNAKSPSAKSLALQPHVTVVEGNLDSVVSIYRIFEEAKSNGGIWGVCCILAFPGLGANADGEEAQGRALANISLEYDVSNFILSSVERGGERDDNKSVLDRLAKVRIERHIKELGKKGLSWTILRPGFFMENYEGTIGSITVGVLKAGLQPTTTIQLIAVDDIGRVAAGVLKRPELFQEQILCIVGDHCTMKEQEEAYERATGRSLPAIPAFLARTLISINGHTKGLIADIERVHKIKEEGAAPDHDSQVAAAKQAYPNIQNFETWAKERASTTSRDRQWNKVTIGKLFTGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSS3</accession>
    <name>A0ABQ8VSS3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_915181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32695" checksum="CA59FE9067A59F41" modified="2025-10-08" version="1">MNTANILLWPEGAVSFTDEDERENALETVRSMITSPNQRVGVSFEESYRDLADPTGRGHPLRRTGLALVSKSNATEMLYFKRNLVPIAESFRLQKSDNPPPLFTFDLKLPKWASGPAIRPISVTASICLDFAIPDPFADLPSTSSSEKPQLILGPARTWDLAVGDAMWEQAKQRAKELDTMLLWCDGGEGGVSGVAGQGMDGVMQVGEGSWIRTVGIKSPSDSHKTFYATIKGSGATIGFIWLLVAGGSGWRMLEVLASGFGTLPLNLRDEFLRWREYRRTRALSHDQEANLLTFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU99</accession>
    <name>A0ABQ8VU99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Scd6-like Sm domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_864303</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="4">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="3">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="38819" checksum="4C3756699D290209" modified="2025-10-08" version="1">MATSFIGKPISLISHSDVRYRGILAGIDPAASTIQLSKVYSMGTENRRPPQDFIPPVPDPYEYIIFRASEVKDLAVDQSVEPPRGRSVHDDPAVLGASSQLPPQIPPSVQQPVPLQQQQPAPSQYTQETPPPGAAGGGGSTSAAAVARARAQRLHTATASLETVERALGDLRVSQQQPANGHGNGTRRRGGAPGNATLKVPTTDFDFESSNRRFIKAHNSDDSDQTSSGEEDDDGSRKKSSSAGTSKTSQAYNPSKSFFDSLTPGQGGGGSAGPRGGAAGMNGAQVARARREEERVKNVATFGEPGRVGHGGMRPGGFGVGMGGGHPNMRGGRGGRGFRGGRGGRGGLSESGPGRRPGGRLSAGNVPAVGVSGGMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUU3</accession>
    <name>A0ABQ8VUU3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_916576</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="22528" checksum="7B5EFF8850CA72CF" modified="2025-10-08" version="1">MLLVSAARSVPFARIAGRRAASAIASKYSNAVYNAALTKSPQTLTKVHTELSSFTATLKQNKDVEAFVHNPTLSAKDRATGLASVFKTLEGAGSKKEPVSDITKNLLTVLSENGRLAEVEGVVDGFNELVSQYNGELNVTVTSAAPLPKDILSRLESTLKQSQTAQKAKTLKVTNKVNPSVLGGVVVDFGDKTIDLSALSRVTKLNAALTQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW85</accession>
    <name>A0ABQ8VW85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_432903</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="57"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="140"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="419"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="432" mass="46221" checksum="B5B690CD935981AB" modified="2025-10-08" version="1">MIIRPLFSNLFSILISISISFCLSYFTSHSLGSITPPCSTTTIRWCIALSSIPHITSKLFIGGLNWDTTDEGLRNYFSQFGKVDACTIMRDPSGTSRGFAFLTFEDPNAVVTVTAREHFLDGKAIDPKRAIPREEHLRNTRYFVGGLAPSTTSDSMKEFFTTYGKVVDATVMLDRESGRSKGFGFVTFEDANNADQLVGKNIVLDEKQIEVKMAQPRSQRDQNRSNTGNGNANSSVISNPINNSFENRMSQTNIPFIPQQQNPMSNMMFQRSMGQIPMMGPGIPMMNVNPMGMMGMNMQSFNPMASMMSGGGMGTSGGAGMGGVGGMNMMGGMNGMGGVGGINALNAMNAMGNPGAMRLGMGPIGATGGMNQSTMMGGSGMGGVGGMMQMRQGANMGAGMAMPFGRMTTNAAGPGPMRMHSRGQHNFHPYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWL6</accession>
    <name>A0ABQ8VWL6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_893496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="8">
        <location>
            <begin position="3"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="207" mass="23450" checksum="1C254CD220B11BD5" modified="2025-10-08" version="1">MSKLTLIVAATRTNGIGEHGKLPWHLPKEMSYFQRVTCNAPSGQKNAVVMGRHTWESIPEKFRPLKDRVNVVISRKENYHFGESVQVHRDLASAMEQLRSQSDPAVHRTFLIGGAMLYSACLQLPKTSPIAFVDRVLLTRVIAPSFDRCNVFVPDFLGEWIGAPDFNGWKQATPEAMSEWVGFEVPEGVQEENGVQYEYQLWVRDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWQ2</accession>
    <name>A0ABQ8VWQ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_808778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="52121" checksum="6AAC72FB3DA3E4CE" modified="2025-10-08" version="1">MDPEKTPLLTTNDLVSRAKCPAGIVASPGPESFAALQEQDVSRLRIQRRKRICAHLILLTIFVLFASSHFDLSHVHGHHPHRFHPHQPQPDDEVSWMENFTDESSDLPVFPELMIRQCAEWPEGEPNSSVQHTFELSIDSELLFLVARGSSINGNVNITQSDEEGDSAVVSIRTHYDDETLLDSIKLCDVVTREGGNGVGLFSSHPHPHRHMHNIYFDINVAFPKHSEKFPLVVSDFRTEMHGIFGHQVANLSEAIVFNSVSLTGAYKPVKVNSLQAHSVRIESPHSPIEGNFTVRKSLRLSTANARINITANLLNDETDKDMTELIMNTANSPIEASVSLFSVDAGEITSSGGAFRVRARNANSPVKVAFPTAPINSTVVLDAKTAVAPLDVQMHGTFEGAFTVHTTPFDKRVVVAEEGLDPEGKGRKRNLIFDRYTGGISEGTVFWGQEEPGKQRGSVRLDTVSGQVSLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWV7</accession>
    <name>A0ABQ8VWV7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_914984</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF66">
        <property type="entry name" value="HISKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="394"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="828"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="742"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="752"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="936" mass="104152" checksum="928AEB013BF47906" modified="2025-10-08" version="1">MNFTSASLPFSHKRFSNNRRVDFEERRGRWSRFKDKAVELIQTAIRAPTGSPSDGLGADGTESSTSTSVFIAAQKLLSAEKDGEDWEINETVINGDNPELLRNERDSGSPFRSDSGGGSISRHSGENGDSNYAYHPPSLRTKLHWLTIQINSFFNQKFDDPQTELDFRKLRWYSTKAWAFPFVMHHNLSLTPMVWPVLVLNWVLYLILNLESTSKTLYGQILYYGGLTLVTVPVPFMVATDMPFRHRIIFQVWVTFAVWYCGLSETVEMRVCHFFVRPNTCFKKDFLANMYYTTALPSIMMIVMTDRLYNAIVQVIQLVLLLAFIIPVQGIYARNVVSFVIFSIFSQGLHYNREITERRLYLLNAQLKMAYKAQQKAQAAQFKASQAKRRFASYIFHEVRVPLHNAAIAFNNMTTDEAFQDFVQKDQGITEDIAALDVSLATVQQVLNDSLDLEKMDAGHFDINPRPFNLHRVIRSTLGPIAVAAAAKNLDLQIDLDERIDQLRPPTDPTSSTNGENSQGTWVVGDEVRLRQVLTNLASNAVKFTPEGTRPGITINTTFVSHRRSMSRHTSGATSGAVDQEEKAFPIDNVVEDLEKGNLSDREGEEKKETFQSQDVLVFRLEISDNGPGIKPSDLVDNQLFQPFAQTKVGRLSKNSTGLGLAIVRQIVSLSGGKLGVNSRRGKGATFWIELFYPLAKSSEIQAAILQEDRLTTPAFATAATIHEVQRWPVVAFADDVKPPMLSGAVSHQPSNPLPPSPPPPPLPPPPPPSFSFSPPSDASFIAPSLPRLGSDAPLLDNPRVSEGINTGNEKLHQVQEIPKPSKAEVSIVPENKDIDDDGPLVIDYDSKKGCIVYTAQDGKECLDLVLGPDARTYDLVSLDNDMPVMTGEDAVKAMREAGRHDVFVVGCTGNALTDDQKRYLDAGADDILIKPINFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWY9</accession>
    <name>A0ABQ8VWY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_360135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="356" mass="40161" checksum="2DC1EFACF377575E" modified="2025-10-08" version="1">MSSSSKDSHLIRYYSKLIETYIQFSLYEEAEATATRVLAVDPSNLIVRLKRGHARRRAGHLVGALADFETVLAIPPKLDTAQALHYDEALRQRDIVVDVLGCSYLELAYAHPSQIAEYNTPSISPSSNEARPGSPLKASLDEPLPTNCRFYNHLGCRRGKKCLFSHAPDARSIRDDLGKNVCLYHLVGKCKWDSFTCIYSHSKDNLPSEYVKDDISKVAWWTNPARIEAVRQLIEKRDARRKKIHEQIERAKKRNIDNNKKSKKKRDNNSDNKDSGDRLPDTNTTAGNRPADSSSSSNSNCDETLVIDWESDSESEGELQFEDVESPSLDLLSYGIKPWEHEEAKALAVAMDNIHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX80</accession>
    <name>A0ABQ8VX80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_811766</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="258"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="457" mass="48776" checksum="B15CF140627295C8" modified="2025-10-08" version="1">MSHSPEPKNPVEKETSSQAVSETDASASNNEMKKESPANPPPLEFPEGGFAGWATVLGAFLVQFCGFGYSASFGVYQAYYTTVYITNETASTISWIGGVNASMSIFIGLISGRLFDKGYFYHMVWGGAVLDIVCLWLLCLAKPDSFYQNFLAQGLGCGIAQGMMYLPCIAVVSHYFRQRRALAMTIVASGSSMGSIIQPIMLNNLLNTNGFKTAAVANAALLTGILVIACALMRTRLPPPPTLMPFKTAIIKFSKDGAYVMGCLGLIIFSIGYYYPLFYIQLDAEKHGLSSHINFYVLVILNVFSFLGRLSPGFLANKVGVPNLITMGMFGCSVVMIGMIGAKSVGSFIVIAILYGYCAGTFISLANPLLAGFATDQMEVGARMGIGFTLSGIGALVGGSIEGALLTTEYVWWKPAVFSGVFALAGVAIMVVMLIMIYERKKAKAKAAAAANASEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYZ1</accession>
    <name>A0ABQ8VYZ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_927839</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="3">
        <location>
            <begin position="23"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="254" mass="26798" checksum="3011303DA0E123D6" modified="2025-10-08" version="1">MAVAKKNSTTKSKASGGKLHTTAHPTWIDMIKECIVTHPEEARTGVSRPTIKKFIEIKYGIDVNASTASQLNRAITSGSEKGIFVLPKGPSGKVKLAPKVRHDAAKENATPAAKKPLLKVKAPSARSRISKKVSSAKAKVIQRPASFRASTGTKLPTIKAPTTKKYVSSKKSSHPRATPSDKHPKKSTIIARKPSSTKKVSIKKVTAKKPAAKASKAKSNASSNAQASTRPKSASKATARSKPASKPTAVAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ29</accession>
    <name>A0ABQ8VZ29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_748972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF3">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046222065" description="DOMON domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="3">
        <location>
            <begin position="28"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="433" mass="48872" checksum="B5C9D8FC0D08B46A" modified="2025-10-08" version="1">MWCLVLPIVLYFFLQLAQVNALKGDGQCGYLVCVNATVHHDTVTYQMTARKEKMGWLALGFGRRMAGSDMVVMWRNEDDSLTISQRHGYDHTEPVVVEEPLRTAFLPLLQPTVWDSNLNPANTLSFSIPLDNSQWVFKPEKNASFEQLIWAYGMTRPASPDPHTTIYGHYAAGMLLLNLEKDIVTSPEGSLDDTTSSPVISQDLLFYSTHELIVLAHGFLITIGMLWFKIHKTLNYVIALPIILGGWTLGPFAVFNARATHFMDAHQICGVLILVLYLLQLSLGRYIHARRGIPNRAVHAPSNILHVFWGLVVISEVKLAQVWSGMNEWAEHTGRPVSQWCHTLWKIWIYTLPVLYLLGLSLLKRQLYQESHGLNPSFTPKHYVALSPDEGNRNTPFDADTDLSSLPDYGYPNHSLNGLTKEAETAVPLLRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ79</accession>
    <name>A0ABQ8VZ79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">JmjC domain-containing histone demethylation protein 1</fullName>
            <ecNumber evidence="5">1.14.11.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">[Histone-H3]-lysine-36 demethylase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_748939</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:42032"/>
            <dbReference type="Rhea" id="RHEA-COMP:9785"/>
            <dbReference type="Rhea" id="RHEA-COMP:9787"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
            <dbReference type="EC" id="1.14.11.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the JHDM1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.27" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15517">
        <property type="entry name" value="PHD_TCF19_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041070">
        <property type="entry name" value="JHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050690">
        <property type="entry name" value="JHDM1_Histone_Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23123">
        <property type="entry name" value="PHD/F-BOX CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17811">
        <property type="entry name" value="JHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="18">
        <location>
            <begin position="250"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="510"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4501679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="620" mass="70915" checksum="A990D02975818E0E" modified="2025-10-08" version="1">MASGRRSTRLNGHNPTEGSPENDATKDQIETTNNESPETKLADDRCPACTPATIAQLDDEVNEQWAMCGACKVWYHWRCTGEGVDLDTIDKWFCKTCLTTDTTGKRAITFRAPARKSDRKRTTKNYANIEAGVNSDPKRFLNMMEGKEIKDDSFRRMEGSQVGLEWAEENESAMKEPIVIESPEGLGMNMPDENFTVDDVGLLVGEKNPIEVIDVASQANAPGWTVGQWVEYYNLEPHQRDKIFNVISLEISGTLLADRILPPRLVRELDWVENFWPSTRKGKGHTYPKVQLYCLMGVQGAWTDWHIDFAGSSVYYHIMHGSKVIFYFIKPTPANLAAYERWSGTEIQYNTWLGDLVDEVVKVTLTAGNTMIIPTGWIHAVYTPQDTLVFGGNFLHSYDIPTQLKVRDIEIRTQVPKKFRFPMFTKLVWYVGDKYMKDLKSGNVPSFRILDSLAALVDFLLSETRALERGSVQAKKEAKEQIPHDRVKDGPALARELAWRLRHASGNVSDDDYAQNGVGHMHKRKRMRSDSPPKFRNFRPKGWDTVLERKAELDSKTLHLGKNEEINKWIEWDNNQGSETEPAVEVSSRKNVITKVRRKAENIVERERIERIVEVWTWKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZJ1</accession>
    <name>A0ABQ8VZJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_976731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="100" mass="11060" checksum="02FAC054C23C5832" modified="2025-10-08" version="1" fragment="single">RRLLCHFSFVAPSSLFRRPQFLTCYELAVQPETPTSLGADTDGDARRTCNLNEVCPLSAVGPEPAQAGAVPSVQHVDPCQSQHPQLERLPHSPLRKRDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZM0</accession>
    <name>A0ABQ8VZM0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_810494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9613" checksum="072C4A5711DC1E99" modified="2025-10-08" version="1">MLPFSGLRLLALVAAHSRSEQIQSSQNNLRVSRISGNLLYVVRRRMLSNVILLNKLTKSVIASFFFVFLVISNNVVRPREIRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZP8</accession>
    <name>A0ABQ8VZP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">General negative regulator of transcription subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_812945</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="13">
        <location>
            <begin position="584"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="241"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="344"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="433"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="468"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4500020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="712" mass="78879" checksum="B44CE52B7C0FB27F" modified="2025-10-08" version="1">MAARKLQTEIDRTLKKVGEGVEYFESVYDKMQASSNQTQKEKLELDLKTQIKKLQRMRDQIKTWYASNDIKDKSALVENRKLIETQMEKFKACEKEMKTKAFSKEGLTQAAKLDPKEQEKEEIMAWLQTKVEELQMQIEQAEAEIESLQGSGKKRGKSSSTAGRAEELEHLNDRRKWHISRLEIVLRLLNNGSLFTEKAVALKDDVAYFVESNTDEDFDEYEGIYDELNLDEEEEKFRGLVHDDEDSDESDDASEDLPPRTPNKKHDDESTTSSRHGSSPILKKATTTLRKGSVDAKAQPITNILKTTVPHPASVLAAPPPRPAVTLPPIRYAAAAAAAIAPVPTPPSATKAAASTNSGPSATSAFSIPTSSSQASQDQVSVVPSSPSLTHPSVTSPMLSSAASVSQQFDGSFYSSQESPAMSEAVISSVGAPVATSSPHRASIARKDSISSPSKAANTTIDAPPPSQSQTNGALQASVLNPSPLPQQVQQYSGVPAPSSPAPQSAQAPQFPPGVKVAVNEQSLLVPQQNVPTARPPSVAQQAPRAVPGSLSDLVVSFENAKQKAVHRMNNLDQVHKLLEGGLSNLPQPQDTERPKYYVPRNPFNTPSYYPQMPNPLLNTPAIFAQLDVETLFYVFYYLPGTYQQFLAAKELKRQSWRFHVKYLTWFQRHSEPQAITEEYEQGVYVYFDWEGSWCQRKKADFRFEYRYLSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B1Z2</accession>
    <name>A0A9W9B1Z2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60s acidic ribosomal protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8J55DRAFT_413734</name>
        <name evidence="6" type="ORF">C8R41DRAFT_764177</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000001">
        <property type="protein sequence ID" value="KAJ4496287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9B1Z2"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001859">
        <property type="entry name" value="Ribosomal_P1/P2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00456">
        <property type="entry name" value="RIBOSOMALP2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="111" mass="11390" checksum="5A33F1C1BCF1B9EE" modified="2023-11-08" version="1">MRYIAAYLLLQLGGNTSPSAADIKKVLSAVGIESEEERLDKLLSELSGKDINTLISEGSSKLSSVPSGGGAAAASAAPAAGGAAPAAEKEEEKKEEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXT4</accession>
    <name>A0ABQ8UXT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBF/Mak21 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_782440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000135">
        <property type="protein sequence ID" value="KAJ4464709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040155">
        <property type="entry name" value="CEBPZ/Mak21-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048">
        <property type="entry name" value="CCAAT-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12048:SF0">
        <property type="entry name" value="CCAAT_ENHANCER-BINDING PROTEIN ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="623"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="889"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="889"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="900"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="930"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="961"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="985"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1020"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4464709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1087" mass="119871" checksum="36BB071374A1B436" modified="2025-10-08" version="1">MVLSRKHTDHKVETDSRDSITTGKAKKTSKKNAVLKEQIQLLGGTAEDYELVRDADEDMDSGSIAVDATLTNEVSKFLEGLNFNIPELPQERPDPKPSKKLPASKVEVPSVVEPSPTSKIKKSGKERTRKDTPSKTPSKAPAIDAKSQTELSNKVVFNPASRFIVPPTSQWYNTVSRLNVTTAPPTVTPAQLNSFHTRAAEIHTEDMKTFISSSSGGSSASEALFLSRIIQSGTLSDRLSALTLLVQSSPVHNLKALETLKEMSERGKGQGGREESLKALRCVVDWWVGGGAPERKLKYFRDQPLLHPGVTDQHLVLWYFEDWLKKYFFSILQILENLSLDPLPYVRTQTLNLIFILLRDKPEQEQNLLRLLVNKLGDTDKSLCSRASYHILQLLQPHAPMKGVVVREITALVLRPAAPTAAATILAAAAFAATTSQLPANIASRKIRFAEDDTPTPTASSATSKSKGKVATTEKKQVNVRARYYATITFNQIVLTPADRDVALKLIDVYFEMFKELLGEGTFSEEGGVVEDGDEIAEVKTDKNGRVFNGKQNKGKGRGKIKEIKGAAGFGEIEDENSKLISAILTGVNRALPFAKIDAKDVGLLKHIDTLFLITHKSTFNISLQALLLIQHIAASLTSGPSSSASISKSIVDRYHRTLYASLHDERLASSSKQAMYLNLLFKSIKTDAGNLENERIKALIKRFVQVLVSGGNGATEFIAGGLYLLGELFSTIPGLRSMVTEVAKQAEEPYDSRKRDPQYAHASSSPLWELTPLLHHYHPAISLHARQLLSSQPLTASADLSLNTLSHFLDRFVYKNAKKISPDATKGKGVSAMQPSASGIEGVKLIKGELATSGDLLMNEEKFLKRRPEDVPVDQLFFHKYFTRKNERVREKHTKTSNEDSEVDSDADSDGGGEMDLTGDEAEIARDDESLDEEEEEGSELDEEEVWKAMQASMPKILADDDDLMNDSDGDPDGDDSSERSSLDDEDLQDEDAEEDSDNEFSLVEGSDNEDLISLNDDGLIEYDGSDAEVGDAEEWGGIGVDSPKSNKRKRNDEKKQRRKKLKSLPTFASYEDYAKMIEDGPEDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXW0</accession>
    <name>A0ABQ8UXW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_861206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000158">
        <property type="protein sequence ID" value="KAJ4463606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="106"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="247" mass="28022" checksum="519B8D2847A4775F" modified="2025-10-08" version="1">MSSIHLYPTVGGLDPILNNTYKDSKGKVQYVVRTPITLTGLGRITTILKSGDFEAILASDSLIQAEYCDDGADQDRILTDSDRTSINLDEAPVVADKQSLLTTENVEETVVEVEEDRMIEVGKIGWALFKNSMITFGKGPEQKADQYFQKESWGFWGRHRVFTGPDGKEYKWVLGFYTPELILNDGSNTPIARFHRRKFILWNTPPGYLEILPSGVDMIDTILITFIYIEKLRKDKERSVSKTNRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY50</accession>
    <name>A0ABQ8UY50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_731080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="115" mass="12940" checksum="7C6CF964600E7DBA" modified="2025-10-08" version="1" fragment="single">NTSGTGKTKLLFEGLCLHWGLYMTCSLDSFNLGAADIPFALDNINENATWTTRLSSTSSDNYASSLKTNIHLVYRAVSEVLLARLIIFKMYLEACSAQGFSVEHRRRWLESQIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0R8</accession>
    <name>A0ABQ8V0R8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Leucine carboxyl methyltransferase 1</fullName>
            <ecNumber evidence="3 8">2.1.1.233</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_779877</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="3 8"/>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4467265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="39363" checksum="61AB846C03EAACB5" modified="2025-10-08" version="1">MLPPPPHDTDAPIRLTDNDAALAKLSAVRQNYLSDQFIKHFVPRASFQPSRPPLINVGTFVRTKAIDDLVNQWMDLSSREGKKCQIISLGAGSDTRFWQLATGTRKDCLSKYIEVDFPEITMKKAMAIKKNKDLSVVLGAPADIQLGQGGTAISSPIYHLLPTDLRGDPSIALGSLTAATENAARLLDPSLPTLLIFECVLAYMSPQESDTLLKWFHTYFSSRGDGILGAIVYEMFGLGDSFGRVMLSNLKTRNVSLPGAVPYPTLESLPSRFLNLDYASAHALTLKDIRRTFIDPIELDRISKLEMLDEIEELDLVLAHYAITWGLSTAHLGNRKAPWGEWGLKRREQHEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1S4</accession>
    <name>A0ABQ8V1S4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_912012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13231" checksum="42CB05C9A3BB5FD1" modified="2025-10-08" version="1">MSSKRGRKRNDNLPPNRARDVQRAFRARRAAHLQALEQRVSELEEENSCLRQALNLPPANRPTLGKGPTGKDKPKTYNPHSLATMSMHSRDFSDSPPSTRMSSHSPENDRYERHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Y9</accession>
    <name>A0ABQ8V1Y9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein disulfide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_852244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF3">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="559"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="143"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4470054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="600" mass="66961" checksum="BFBE73B3FC8B7A2A" modified="2025-10-08" version="1">MILKLWQLFRDLPIPFLLLSFSIVCVALPVHSSELTPENFKSSIASGVWLIEHFSPYCGHCRAFAPTWEELAERNKEGSAEATGVKLAQVNCAVHGDLCSANNVKGYPQLNIYNNGDFVETFKGARDVERLTEFIKRHAPTPPLPTPPVPETVLEETNYVANPNPSGSVLVLDESNFQSTIEEGPVFVKFFAPWCGHCKKLAPTWKKLAQSMQHKLTVAEVDCESHKALCKENNIGGFPTLVYIADSSHTEYGGGRKLEQLEEFAEKASNSEPKSISPDELKNHVSVEKSIYVLLYPSSEPKLPSILRPLFSSLLGSPMVYTIADPPPSMKSHFSIPSTSAWAIVALKDHDYTIPAAVYSTSTSASSLKKDPTEIDLIKTWLLHNRLPTAIELTQDSFQSVMNSPARPLVVLAAVTPNIKDKVQERMEEIGQRWRARTQGSGMLSENGKERPIVFAWMDIGKWKDWMKSMYGIKYKGSLELDDVEVVVTDHKALVYYDIGHAGLPIKLTSSQSVFSMLDGIAQGNIYPKNSENFIERVARYLNGKLQTIESYIINHPKHMAFLVLLGFVFVVYAIRRALADEPMDKDYVRVGKGKADRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V252</accession>
    <name>A0ABQ8V252_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Muts domain V-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_912080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03281">
        <property type="entry name" value="ABC_MSH5_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="775"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="854"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="856"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="987" mass="110522" checksum="47AC2700D4D385C3" modified="2025-10-08" version="1">MPGFYRGGGQNRKRKFHATRRQKQPQASTRSISGTPAPSNTNEEDVQSEDGEDSPALQKKVRWEGRHRANTEDPTEDGTMEDTAEENQDSCEPQASKIDRIFLTAWCQNRRVGMAYYDPIKCSIYVLEDTEETSHFDVTKMVLEQASPDIVLTSSRSDDEFMDAVRELVEVSSGIFQIRPNKEFSAAKGKDRLISLQLLSDLPQDEDQSSILSSDDGSSISRNAYEFMAKRSGAMHDPTTKRWNASIRLFNFASLESSPLCMASIGALLDQLVRTRAVDDLEDEGIRGLEVRDIECLALPQLLRIEQTHGSSLQVFENEDHASMHSNKTKEGLSLAGILNVTNTTLGRVLMRSWLLRPSLSLSVIKSRHDAVECFLRLENVTTVTTLRGHLKGIKNVPRILSVLRSGKAKFVEWQGLVKFTVLCAMLKETLTELYEASGLDIVQKLLPALDISCFREIGTRINDMIDWEESTEARRICVRPHIDEELDNRKHVYHGIDTVLSKVAERISRIIPSDYASSLNIVYFPQLGFLICVPMQEEWRTEVGVRVIDGWSFQFSSESHVYFKSQEMHDMDAHIGDLHSLIVDREIEIIQALLEEILVHDAAMSHACDVCAELDCLLAFADVSRAYDYQRPVMVEDNIIDIVQGRHPLQELVVDTFVPNDARITGGDGYFSIFTNTTEVDTQLEENHLKLWNSVLLCTGANACGKSVYLKQIALIQYMAQIGCFVPAEAATLGIVDKIFTRISTRESVSKVQSAFMIDLNQVSLALRNCTARSLILLDEFGKGTLPTDGAGLLCGVIKHLLARKSNCPKILVATHFHDVFREEILDPKLIPISFLHMQVMFTAARDGSLLEPGSPSNSLTSRSLSATLSATKPSSSVATQEGSREEITYLYRVMEGLSMDSHAAKCAELFGIPPRLVQRAQYVSQLLSSYEIGRLLDERMSEKEVLELEEAEAICRRFLGWNLTANNVSVKEKLGEVLGRQHEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V288</accession>
    <name>A0ABQ8V288_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_110775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23994" checksum="C0456A26035FEFE3" modified="2025-10-08" version="1">MLPYLELIPRDILEYIAFLVALTPIPVFSPPQELLNLLLTSSTLYSSLCISSAPHLYARIFRSTFDLDMNSPSYDASKITDSGLTFDLVSRYRLLRRVRRMEFSNKMMLEDLRVAMQTVIESKRVNEAHLKSAGFSEFTFSYAEQCLTKHQIAQTHAAFDYETNLVLWLLVLTWSRDDVTKIAQETRENFLILLRPLVLGVSQIDCWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2G9</accession>
    <name>A0ABQ8V2G9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_837024</name>
        <name evidence="3" type="ORF">C8R41DRAFT_858815</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000129">
        <property type="protein sequence ID" value="KAJ4465218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053027">
        <property type="entry name" value="AGGF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106:SF24">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="87"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4487503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="175" mass="19834" checksum="E919225F7AC79EF4" modified="2025-10-08" version="1">MEDGEITSRSPSNKRHRSVHGASECEPLSSNYAHEQFQGLTWDTASDEWDDSNRSQIHPKAGLRLVVLNSRTLPKSNVAIIDGYPEVQLGRDNPMSDHIPRVRLKEMEVSKLHASIYWDQFWDGWGVVDMASKHGTYLHSSALTIGNSQAEERKVGSNPPVPNCRSYIKTTRRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2N5</accession>
    <name>A0ABQ8V2N5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_924721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="156"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="2">
        <location>
            <begin position="339"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4470996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="59130" checksum="51E04364795E1AD5" modified="2025-10-08" version="1">MTFLRSQTFKSELTKDDSNSMKPIIPFLLFDHHCSLQEFTNSQEMDTGASSMFYQAKNFAIYGGNFIAIGGDDINKIHKWLNAPDCSANFVTAVNNKCLGTGQWIFELDKYKEWRSKQCKHGLLWIQGPGLTMLLKKGMFDLIRNYSWGRKDLSNQMGLSSEGIHPALNTLYKSKPFEQHTHRELENILETMIQDRNDMTIAVDALDECKEADACKVLNWLTTSSYQLRIVVTSRSNPELVVQNLLQIQLGGPESRIDEDIASYIELKIHDQPWFKGDIIGEIKDTLNKGAQGIFRWVDCQMMQLQKWKRKRNVKEALKTLPATLTETYDQALESLTEEEKEDVQHLLLWLLYAFEPLTTRKVNEIWKINLLEQKFDPDEMELQVEKDIPSTLVTVGQNDIFQLAHASVKEYLISYRQSKEMQDSLSFNEHLAHDVMTQTTIIYLMQDDNTEFKKRSFVAYALQHWLQPCIKSGGVQSTRPKSEFDMCNVDKQCTVFKMGRNVQELFFYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V363</accession>
    <name>A0ABQ8V363_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="1">
        <location>
            <begin position="29"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="131" mass="15880" checksum="63F8F7D6BCF154E8" modified="2025-10-08" version="1">MRRSFDELQQRFIKREMRAISDADAEGYLYAYIHFAEWKVGSTKDFNRRREEWDRDCPDVWRIWLPPIWVAKRRRAESLAHLMLEMVCIDRPHAYCESCQRKHIEKFIFSEPWPIVWSTIVLPILLRAAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3B7</accession>
    <name>A0ABQ8V3B7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045163977" evidence="1">
        <location>
            <begin position="25"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="378" mass="41928" checksum="EC3441DB6A4543E0" modified="2025-10-08" version="1">MFPTEPNTICCLFLLCSIFLTSNAAIDRHSLVTRYNPTRNASNPTTPMQVGNGNFAFGADVTSLQTFLPFATMSSWGWKNDSLPPNRTIEDVYNYKGESWYNHGRLVQYDFGGDPEIEQWLTANPNRVNLGIVGLVFLDAQTGLIQNVLESDLSDVHQTLDLWTGIMSSEFTYEDTAINVTTTSAQDISAISVTVSSPLLFPNTSNAFTRLGIFLDFPWGDGSQKFSAPFVGNFSSALFNNHTTTLLDHSEYQAQIKHRMVDAIFYTAVESSTKFDITRDSPVAHRYTILPHSDTNSLSLVISYNSTLPSSLPSSASLVQSSIATWESYWMDGGFIDLITGSTDSRADELQRRIILSRYLMGVNEAGEDPPQEVMYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3E5</accession>
    <name>A0ABQ8V3E5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA ligase</fullName>
            <ecNumber evidence="1">6.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_776413</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m = (ribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="T4-Rnl1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012387">
        <property type="entry name" value="Trl1_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015966">
        <property type="entry name" value="tRNA_lig_kin_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015965">
        <property type="entry name" value="tRNA_lig_PDEase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004:SF1">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08302">
        <property type="entry name" value="tRNA_lig_CPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08303">
        <property type="entry name" value="tRNA_lig_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019634">
        <property type="entry name" value="tRNA_lig_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="T4 RNA ligase 1-like N-terminal" evidence="5">
        <location>
            <begin position="64"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase kinase" evidence="4">
        <location>
            <begin position="426"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase phosphodiesterase" evidence="3">
        <location>
            <begin position="603"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="613"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4471926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="810" mass="91751" checksum="7C573C8AB4211F6C" modified="2025-10-08" version="1">MPHPATKSEDSDLIDALLKLSTKNPKLVKSTVYDAPADPTLGVRSWKMNEYKYYDVPSPFPTLARGLFTVQVGRDPNSHRIVIRGYDKFFNIGEVPWTTWSSLKMHTAAPYTLSLKSNGCIIFIGALTPEKLVITSKHSLGPIGQSEKSHAEAGEGWLKRYLEEKGRTEAELAKTLWDNNWTAIAELCDDSFEEHVLGYPPHLTGLHLHGLNTCTKEFSTLPHSTVDEFASEWGFIKTESIVFNSIEEVQKFTDEVSKTQHWNGQAVEGFVVRTHVTTPPSGNENDRGKTPYAPGSTFFFKVKFDEPYLMYRDWREVTKTILSAHKKGARVAKTLENTVPRNKMKRPETRVYVRWVIGEILRDPSLFKEYTKGKGIIATRERFLQWLEAEKGKKEISSDGGRLDAENFGSETEQKAQMKPEFGKTVIVPVAIPGCGKTTVAVALTHIFGFGHTQSDDVHVKKSAPVFLKNVQNLLKSYDVVIADKNNHLRQHRTQLRELTQKMIPPVRLLALNWSLASYPQSTVHRICGDRVLVRGDNHQTLRADASKFRAHEDVIWMFITQTEELTPAEVDAIIDMDLEEDFVSAVNRAVDGICQELDLPRPTSENIAEGIEKATGYRPATKKADEESKQKLKEKEPRYFGIVPEIHLEQVLTKVLGENPTMYTMWMHLKESQRITQRPHITVIHKKSLPGEIELWERCMDLHSSKNPPMFEFKLKNIIWNDRVMAVVVGDLEVLPGSDAEQKGAEFIGKLSEQIRTRLHITVGTKNHNIQPVEAKALVEEWRQGTGGLQTMEFSEGVLVQGRIKGLTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3L4</accession>
    <name>A0ABQ8V3L4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_859517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000136">
        <property type="protein sequence ID" value="KAJ4464700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29525" checksum="C026BF9F3AE49251" modified="2025-10-08" version="1">MTSIHPMQTSIRLARPNEYPAAARVLTRAFAQDPAFNWYGGVKQAVPHYESNSVDAVKTMRNLRYFQEAVLKMMVISGGYVVVVVVPNGTKGIQQPGEEKEMIIGVTLWLKPGQSLDLGILDIIRSGGLKALRGWGFMGLKRVFLDFTPAVERSLKKEFHSRNLDRLDSWHLLEMVVPEFEGMGICSLMMKDGFTRTTPKPVHLEATKARTRDIYAHFGFEVDEEHQFGVGSVDENGIRARGEKATGYPEWVMTKWNYTSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3U2</accession>
    <name>A0ABQ8V3U2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_897634</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="3 7"/>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046067911" description="Alpha-galactosidase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="9">
        <location>
            <begin position="328"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4472742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="548" mass="58538" checksum="223E1976F75B28BA" modified="2025-10-08" version="1">MTRKSWNASRLVQLVVITIFAEYCCALNNGLATTPAMGWNPYNAYACDTVESQYHSNAQALVDLGLDSLGYEYLNLDCGWQGTARNSSGGITWNTAAIPNGVPALGKFVHDLGLKFGVYSDGGYFACDTVGGTAHFLGSLGFEMQDAATFASWGADYLKYDNCYAVSTTDFVDFDPPIEPHYTTMRDALSATDRPILFSACEWGVQDPARWPASAVVNSWRISNDIGPPSSWDNIFRIVNQLVPITGFAGPGGWNDLDLLEVGNIGLTMAEQQTHFTFWAAAKSPLIISTDLTEISEEAVGILTNTRVIALNQDSLGQSISFKRRYTNDHDVWAGSLSDGSMVAVVIEMQNSPRAITFNLSDVGYASATAINVITGASLGTLENSYTSTFDAHGSLVLKLSNPVIAPQPTFTFYDAAASGNVLAGGASTRIVNNTITVVGFVGNGGTLQFTGVDGGASGGIKLLSVDYINADFTPTNTDCSNCRNAFMSVNGGTAVQVQMPLSGQNWDILFHGYLVSLSGFKPGKTNTVQISNPSAYTPDFYRLGVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V457</accession>
    <name>A0ABQ8V457_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane bound O-acyl transferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_849972</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF67">
        <property type="entry name" value="WAX SYNTHASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="8">
        <location>
            <begin position="231"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4472358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="44995" checksum="09552EA00C482BE5" modified="2025-10-08" version="1">MLNSTATESPSVVPIRQSFSVGPYLILPDLILATILALGLKFQFRVLFFALFSYVCFSGVLCTTGDRMQDYSIGSTLGGQFFTATHLLLFAEPLAHYRHCADKDDPRNKTLWRRMLWSLCIVHSPRGIGWNYQVSNVPPRPLPTSKWTFIRSRVVQIIKFYLIMDLAQSYIHMNSLFTDPPPNATITSQGWLLQIISGAAWMTTPYAGMSMQYLIFAVFSVGLGFSSPEDWPDTFGTWKHAYTVRNFWGKFWHQMIRRYVTSIGKFVCRQLGFQPGTWLSSYTQLYIAFFVSAILHCFGDVMVGWEYLGASFPFFITQAFGITLEDIVIDVIRRSRLQVTPAFAKFVGYMWLMFWMSFSLPWYIDWAVNAKLGQSEVLPVSPVRYALRALSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V496</accession>
    <name>A0ABQ8V496_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_858310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000125">
        <property type="protein sequence ID" value="KAJ4465580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="92" mass="10502" checksum="607D8CF47FDA2263" modified="2025-10-08" version="1">MRTEVGNSSKVHIFLSWFDLGILQIGWVRVIFSLPTRNLGTLFPKSITPPSHLAHVEWFTKFSQKPEPHTGLYRANPQLCKDGSRAIEDQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4P3</accession>
    <name>A0ABQ8V4P3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="311" mass="34124" checksum="72F70C5FC4D27D9A" modified="2025-10-08" version="1">MSTSSYPVLPPTTNELTPSQRLRLMRSTRKLGEMLGTTPVINSSSEFGQHPSASHRDTPSISLHHSSSPRFAHAPKKSKALPRPLVLSLQSLPASFSSPRSSGPTSPLSPTSISTNIASSSSYRDDHDSLSDSLQTRRKRMAKLTRTLGENIPPELVFNSQLHHSHSQTTSVEAASALANLTVTANGFTKPSRHTQETVVPLRMKRLPQTPTTMSRSASLRAPSPSFVARRMMRKRHGQTHTTSHVELTPSGGRKSSDTIRSTVSSCSTASEPSHLNETKRTYRKQAGWSGEWNRQDMDEVMNRLRGLKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4W6</accession>
    <name>A0ABQ8V4W6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_871656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046341109" evidence="2">
        <location>
            <begin position="18"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="35539" checksum="D73025F367A48482" modified="2025-10-08" version="1">MVVVLLLLTMMNVPVVGIRVSTTRGYDDDDDIWGAWGVGLHNVGEWISPAFSPRDQILGDRWSHMRNGITWHHGVAEETGQLLLMVMAVDADVAGPVPVDVTLKTQYPYLHTVLSVLPKDIAHDLRGVLGFLERGGEGFVCGGGWFEENKDKVRGTAEEWVLGQKMFRELVKSQLGTELGLGLKRGREEAKDEDKEDKEEKEEKERSLSLKNPKKPRLSPSKAQDLPQHILHSPLDLSNIPDAQESGYHDSQADDLDSPTQFFSLPLSPSPPLSALSTAPSHIPHTWQNPKPKKHWLVVLITSDCVARAKTRGMRLFLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V510</accession>
    <name>A0ABQ8V510_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein PSF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_924108</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS3/PSF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21693">
        <property type="entry name" value="GINS_B_Psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055221">
        <property type="entry name" value="PSF3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22466">
        <property type="entry name" value="PSF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF3 N-terminal" evidence="8">
        <location>
            <begin position="6"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="70"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4473515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="21822" checksum="5DEC705C7254E292" modified="2025-10-08" version="1">MDNDYFSIDAILAENQKVQCKFKQRIPEMGHLGGGSERDITPLNKRQIPIWLAYIIIYSDWADFDIPQPFSNKVRNALRAEPRSVRLSNLVGAGTGWYVFGKTIMDMLGDEQGVEMSEMLVTTFKGRLVDVIDQAQHFAALGPVGGGGGGGIDSAPQMFREGLDTTERELFVLAQESARRMKKWYEESSGGTKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V517</accession>
    <name>A0ABQ8V517_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Dihydroxyacetone kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_923772</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF14">
        <property type="entry name" value="DIHYDROXYACETONE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="12">
        <location>
            <begin position="9"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="11">
        <location>
            <begin position="407"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4474757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="606" mass="63511" checksum="632AAB0E489BFF99" modified="2025-10-08" version="1">MASKHLINSPSTLVIESLEGLCLLNPDLRLDKDARVLFRPFSSDSSQRVALICGGGSGHEPAHAAFVGKGLLTAAVSGSVFASPSGKQVRRAVELVHPQNLGSGSTEEGAGTLIIVKNYTGDVLNFGLAKEALGSYPAYANSVRFITVADDVAVPRSRITLVGRRGLAGTVLTYKIIGELAARGASLDEVEKVGQYVVENLASIGVATGHSHVPGTERGQDVLGDDEIEVGMGIHNEPGVLRLHGSSGLPPPLSEIMPRLVNLLTVSQDEDPERGWVSFAPSADVVLMVNNLGGLSPLELSAVSVEAIKAISDKGLKIKRVLCGTYMTSLNMPGFSLTLLKLPSAGQEPSQDLLLSLLDSPPEASGWGWVSGRAPVPLTDQIVSTPSSLSTSVSTTKTTSSNDPGARQVVEVIRRACNALIHVEPELTRMDTVAGDGDCGLTLKAGAEGVLSLIQSNEINGHDLPTTFIAIAGVAEDKMGGTSGGLYSIFFSALAQGLRSSSSTPEVNWPSALNHALTKLYTYTRARPPSRTLVDPLDAFVKGLSTEKADFYGSFEKAQEAARATRGMQAKAGRAVYGGGEEGEEEMDPGAWGVAILLKAIIGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5H1</accession>
    <name>A0ABQ8V5H1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632264" evidence="2">
        <location>
            <begin position="20"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="39606" checksum="A99869AA794D23C2" modified="2025-10-08" version="1">MLRAFVFALVAILVIQAYAAVIPNTIPVSQSVNEQQLVDSSSMLEVRGLGDRLRKFKGKFRQKLNPTSKSKDNDSIRAADTPSRSKASLNEGNETVIPSGAANSTTPRKHRGGQRKMGPQPAFEEEDQSKGKEPALPNSSIFNDTSQITEGSNTTSQTSSSTKHHQHHHPHRHHRTSNATANKHDDDDDDTSTLKPPTRHRGSTVTTSIPTKPDLKRVNSSMSSGSDYAVTLSSEDGNDTRQSAKDPRPERLRVPGHHRTSSSASGRNRDSIDTVTRPGRGRPRSGSMNKSNDRSSTREREREKEREREKAENRASALYAATQNTQMTQNAQSIAFNANTFATNYGNTAATGPGMTKPPGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5I7</accession>
    <name>A0ABQ8V5I7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056021">
        <property type="entry name" value="DUF7600"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24539">
        <property type="entry name" value="DUF7600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="217"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="707" mass="78894" checksum="16606E0F6CF35F64" modified="2025-10-08" version="1">MAPTSRCHCIVCGISIECAIDHAGSETSWMSEFRAIYAPRKDSISAFLSGPGERRQFSDVIPMGEPAEMTEIELLWFDWDPSWANNSSRSPWGFPVHCACWDIMVAVRPGRRPNVQHLFDLCRSFPVQGALNFGHNYGGAVPYGARIILSLGEEPWLSPTPTIRSEPQYKCNPFYHLELTRLFQQDSAVSPEGSYLPTVDPAVTSSGHKVNLTLGESDPFNKLPIEILLSLLYYLPSPSVASLKLASRGYAAIVLPDRFWFSRFWPNQEFEHVFEAIQHAALWGGRWKSLFDSVKDLHRRLNTRDAMSNRKRVWELAKSLQALLDEVGEGPCAGDPVHSFFEPNAPTDDTTCWVTASRNLKSPKEIFGSGSRSLFERLLVLPSVVISIFISTIEVSGHCYISGLRLELDDGESSVLGYIHPRNETLVTWDAATTTRVSIAGFHVAQNNQGVSALAILSTEGYLSNWVGEFQGIPKRRLTLDLVEGGCRDPARFLKGGFDALRLVFLSISVSTDTEPSSILLDPAASLRNTASWLPDIPEPNLSFMGEDYQGDLPLTIINFDGQNGRNLRDFVISIWSQDGEISGIKISYVHLLDGPKTLLLGDELLDAPVDEVDRCDISIDYANGEYITGMEIFQRNRASLALKLSTNWDRAEQYIPASGKPDFSQRTDWGKRSFYPNGTVVGFYTLFVSLQSLYLIRDWAYSCSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5L3</accession>
    <name>A0ABQ8V5L3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-methionine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_847883</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF512">
        <property type="entry name" value="SOBREMESA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4474526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="575" mass="62219" checksum="FEF59008E106A6FE" modified="2025-10-08" version="1">MSSSYVALKSPLNLSFTNSPPASPASPRRQSRDSEDSLRALEISDGVPLAEPSHHSRNRSFSMRSFDFDLLPLSTSLTDPDMVHGEHGEKNISLLNGIALVVGMQIGSGIFSSPGVVVANTRTVGASLCVWIASGLLGWTGASSFAELGSAIPQNGGAQAYLAYAYGPLLAYLFAWTAIIALRPGGNAVISLIFAEYLNRIFWHSTRDNISPDDIPAWAIKLTACVAVLLVTALCVWDRKLGARAAVVFTSVKIMCLVFIIVLGIVQLARGKASPSLGEPWFKGSSTSPSEYSLAFYSGLWAFDGWDQANYVAGEMHQPGKNIPRAIHSSMVIVIVLFLLANVSYFAVLDKNLVGLSNTVAMDFGRAIFGPWGGTVFAFMVAFSCFGALNGGFFTASRLIYAAGRENYLPALFGRLHKTRKTPLNATLLQTVLTLVFVLVGGGFRSLVNFSVVASWSFYFLTVLGLVILRIKEPMLERPYKTWIVTPLIFCGVALFLLVMPIIAAPLEAVAVLVFILAGVPVYYITHRNDQDIPRILGWVKPLIAKIQGKPAHGDGWVAVSTDGDENVEMMEGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5V2</accession>
    <name>A0ABQ8V5V2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_846408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047441214" evidence="1">
        <location>
            <begin position="19"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="21921" checksum="5541B8738641E34A" modified="2025-10-08" version="1">MHINLAYLLFALWSVAHAAPTLPSEKTNLKHHSARGRPISFPDPATVATVHVKLDPRNPNRLSTPCMDECGLKLKSIFEEWMRNAKLFEIEKKMIKEGKKPTVNDLPDIPLVPLEIVIEPDSVSALESIKFWGTGVKDIPGFVKGCEKKEDLCWGDVYDHRGVAFFWSAPNVSWVNIMNGYGVGVKEHRGKFTAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6K0</accession>
    <name>A0ABQ8V6K0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_904882</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008909">
        <property type="entry name" value="PRK12273.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="4">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="5">
        <location>
            <begin position="417"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4476111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="473" mass="50898" checksum="1578C1E75CC4B96F" modified="2025-10-08" version="1">MTVTPMSSTQQFRTERDTFGELKVPSDRYWGAQTQRSLQNFDIGGPTERLPPPLIKAFGILKKAASIVNVGYGLDAKIGKAIQQAADDVISGQLNDHFPLVVFQTGSGTQSNMNVNEVISNRAIEILGGELGSKKPVHPNDHVNMSQSSNDTFPTAMHIAAVTELTLSLIPALSELHDALDAKSKAFEHIVKIGRTHLQDATPLTLGQEFSGYVQQISNGIERVKGVLPRLSLLAQGGTAVGTGLNTRRGFDVKIAEEITKLTGMEFKTAPNKFEALAAHDALVEAHGALNVLACSLMKIANDIRYLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAVTMVAAQVMGNQTTVSIAGSNGQFELNVFKPVIIKNVLQSIRLLADGSRSFTKNCVVGIQANEPRIKSLLNESLMLATILNNHLGYDNVARCAKKAHKEGTTLKEATVSLGLLSPEEFDEKVRPELMLYPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7N7</accession>
    <name>A0ABQ8V7N7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chloroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_925082</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF1">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="35"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4469636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="43474" checksum="8477961C10ED6005" modified="2025-10-08" version="1">MKHTSLAESYAHAHPPTDKRTISFDPALQYVSTTGQHAFVPPGPGDFRGPCPGVNALANHGYIPHNGIVTIDQLVNGSYTVFGMGRDLALSLAVYSTGMDGDIASLSLSIGEGDKAILAQNGLTGSHNNFEVDASPIKGDLFQYGNNHDGQMSQFVQLYNLQSNVSDPSQVNYDVDLLTSFRLSRFQQSIDKNPYFFNGPLTGVFVQPAAYYFIYRLMANKSEEYPEGRLDRETLKSFYGITGSEEDDFVYTSGYERIPDNWYKRAIGDEYGIVSYFDELSGIALAHPKFFSIGGNTGQVDSFTGVDLTDLTGGVYHANTLLEGNNLKCFTLQAMMMHFPIGATGPLEGVLDELADMVDPLLQSWDCPELEKIDESLLEKFPGYSRYQGVERRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8B3</accession>
    <name>A0ABQ8V8B3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_911108</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045047">
        <property type="entry name" value="Ard1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091:SF4">
        <property type="entry name" value="N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4479855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="154" mass="17796" checksum="D2EC2C3BBED88A07" modified="2025-10-08" version="1">MNIRRARIEDLPGMQACNLRNLPENYSMKYYLYHCATWPSISYVAEDKGRIVGYILAKMEEETAETEQPHGHVTSISVLRSYRRLGIAKKLMLLSQESMASRRASHVALHVRKSNRAALSLYRDTLGFEVHDIEQKYYADGEDAYAMRLTLKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Y6</accession>
    <name>A0ABQ8V8Y6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_771388</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4480310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="46865" checksum="36302C71674588B8" modified="2025-10-08" version="1">MMGLFSQAGSHFRNVAGSNTKPRGSSEDDRAPSDTEPDDTSILDENEGSIISSMISQLRVGMDLSRVTFPTFVLEPRSMLERITDFMAHPDLIFGAEECDDPEERFLRVLQYYLAGWHIKPKGVKKPYNPVLGEFFRCQYDYPNNTQGFYIAEQVSHHPPVSAFFYISPENRLMILGELRPKSKFLGNSVSTTMEGENRVTLLGKPEDGEYVITMPNMYARGILFGKMVLELGDTCIAKNEKNGIYCDLEFKTKGFFSGTYNAIAGRIRHKNNDVGELSGRWSHVMDYKNTKTGAKRVIFDAVKDGQAVSPKWVPPEDQQEPNESRRLWTQLTQAIIAKDMEAATDAKSAVEDAQRESRKKLDESGKAHVPRFFVQKDGRWVPKLQIPKDPKEATAAVRQWIFGSITRPDEKAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9T1</accession>
    <name>A0ABQ8V9T1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_841286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058268">
        <property type="entry name" value="DUF7962"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25907">
        <property type="entry name" value="DUF7962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4482734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="37676" checksum="A39D16617AE803C8" modified="2025-10-08" version="1">MSPCNPGVILYRYNASPFSVKIDNVLMLKNVPYATVTVANVLPRPEITELLGLTYRRIPILAIGNDIYCDTSLIAAAIERRFPTSQGFGTIFPPKKHGGSPDTGLLKAFTQHYADTVLFNLGPILLPWDRFPDFFLKDRQTIAPNLNVEVMMNSQGKAMNAFSAHLALVNEQLKDGREWLFDTELPSLADIGIHFTYNWVCGFPNTKSLFDEAKFPYALRWLDRLNKFIKTTRNDFPTSVSLTGPEAADSIAKSSYEPYNIIGFDAFEAARLNLVKNQMVNVVPDDTGPQFATSGKLVAFNHEEIVIETKGTMNAIFRCHFPRIGFTPKGVQHHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAG8</accession>
    <name>A0ABQ8VAG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_839608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="39190" checksum="0C06A690ABEE4935" modified="2025-10-08" version="1">MSLHFSVEPLPPPRPTSFEIMKELHDSRFKEFPVKRDAEPAEVIYAQFAPPTPPKTSPRFNAQDAEITVVSSDNVLFRLHKMNIQVTSGGLLQSQSKGPGIQDDFLTLTEPADVLEILFEFLYPDYETDLERLEFNALLSVAEAAEKYGVFYAMSHCTFCLRCVYPKAMFPALELMTSTCIRKHTLFHSAELIRFAVKYRKEKMLAELTPPLLDMELEEVITILPPTAFGEFCIFRDRWIKVLLKCFALIIESSADHDQNQNYPCFKEPQTQITRRLKSFLDDAIAKPSSLFPDQLDRSFLQLEAILMGNGCAWCKDAFITFKDCVLDEVKELPRTFAVELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAZ1</accession>
    <name>A0ABQ8VAZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_444877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="396" mass="43602" checksum="825DD59E671D3469" modified="2025-10-08" version="1">MLLKIPSSSIKQSRSLRLFLIIPMTDTLGISEAQILGLFLASVFWGMLLITFVQAMRCMLWDLNVPGGRLKRASTINWPMLVVALLLMALSTFDVSLGLMHSIEAFIFYTGPGGSAARFTGLTDWVNILKTCNVVFGKVISDGVLVYRCWAVCDRRIIVVVFPILLWMGYLGTGIFVIYLEASAGNPKVLLTGGLSSLTPSITAGWTMSLVNNIITTGVIVYRIRRVDQTNALFGIQSQGSSLQGTRGLFGRQKRQRTKLQNVIRIIVESGLMYTTIAFITFITFVVGSNSFYPTSDAELQILSIAFNLIIIRISAHPSGSDDHSTSVQSAPQTFPLRKFSSAPKSTNESTQIESGAYRTGMNKPQQESFLEVEEGNWAQSLTVKPQALNMEITDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB56</accession>
    <name>A0ABQ8VB56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein eL42</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">60S ribosomal protein L41</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">60S ribosomal protein L44</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_497315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4479843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="106" mass="12212" checksum="7157C17AB773194C" modified="2025-10-08" version="1">MVNVPKTRRTYCKGKTCKKHTPHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKAQMTLKRCKHFELGGEKKTKGAALTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBL7</accession>
    <name>A0ABQ8VBL7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="364" mass="38376" checksum="599724331BE4A3E8" modified="2025-10-08" version="1">MLASIYSSANNSAFNSPAGMLGHQQLPSLSPQPPHLGLGLNSGYNSNSNGFTPSDSPSPPLSSAGIRLPNAPLSDIAEYRSNSGNINGEYNSGEYIEYNEYDRNSNEPELGYPESYDSPYLNNYNRLPTSVSPSPHPRTPHSLPLPLSSTNSPYSGSSHLGSPHLGSPHLGSPGNMVPSPLAEAQLLQSQASAGSSSNGSTSTLMDIYSSPETLVNPDSANTKISPMLMPPSLSRELTVPVGSGQRNKSHTISTSTPYEAYLNASREARGQERMLYGTPRERSGSVSSVYSTHSASSASSAHSSRASSILLSAHSVHASLPEIEGEDTVLVSVSGSMDELHMGLGGLHEMHETLDPSVLNGERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBR5</accession>
    <name>A0ABQ8VBR5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_837753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045592924" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11429" checksum="C49A430252379495" modified="2025-10-08" version="1">MMFSAYGVTACTFLSFHLITAHYCLQTQLCGSPLAMRWRFKAEVEAGGIQVSAASERVKRDTKLNDLDKFNHSGVLWASHRESNIYCTHIAKISFSFPRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC42</accession>
    <name>A0ABQ8VC42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_840347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="149" mass="16297" checksum="A85410497F81EE67" modified="2025-10-08" version="1">MNSYYHDSNVSISNNLVPPSCPAIKTEVSQICLPDASSQRVASLVASANPPPLSSDPSRSIQRDPCPRGGSSSANSSSSRASIVHPYARLYAKKEEGKRRKIWNHALEKSLFNPFELSSLGAPHRRTIYMASLEAHVDELHSQLLRSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCF1</accession>
    <name>A0ABQ8VCF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Metallo-dependent hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_920958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46363">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46363:SF1">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4487427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="38204" checksum="CF36A8BD8789DDBB" modified="2025-10-08" version="1">MGKGKSKGPLAESFLQLPGHSSTIQVIDTHTHLASTFETYYSKYRMDSKYHTVFDFIKGMYAGKHIEAVIDVWCEAPVRKLWKEFADSALREEDRKSKWGGLEYWFVMGVHPHEAKLYNDEVEADILEAMEHPRCVGWGEMGLDYHYDNSPRNIQQAVFSRQLKHAVRLNKPLTIHTREADVDTERILKELVPKEHPIHIHCFTDSPDFGQRLLDYFPNLCIGITGVVTFATNLDTPALIRRMSPPSVSPLRILLETDAPYMVPANIYTSLQDLPNSNDLKGRRLPLSHSAMIPWTADFVAGIVNEHWEGDENKVDSDWVLKVARDNARKVYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCI0</accession>
    <name>A0ABQ8VCI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="397" mass="43858" checksum="3DE102997F897B54" modified="2025-10-08" version="1">MSEPTPSTMDSNLPGNVNTSKKRGGQKTKHVEDIQSTATEPAKTVNKRKPATQGGPGTKTKKTKKATTTNSAGQKSVCVPLQDVTNELGNVSAPAPTNETRQNPDDNAHALTPVANVGNGPALTPNIHTLVETHTLTPTDLEAAKAQFFKEAEERFKDLERAQKVNQPLAATAANMARTPERVVEDRQVPAAPKRQWPPIRAHKHDRGVFQNQYRNISAEKPAVPLLTAQNLEGQVEQVTGTVETIERPQGEAGDGKRGFCLQDAVDLEQNGDKYADFLARVRANATMARIDLNKTYRQQDPDLISLVCRKTAIDLPYFGKERFPGYWATREALKQYIKNQRKDAERQRKARVSGKRFLKDKRFRSGNVVYISDGEVSVEDNHGEGPSGTHHDEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCI5</accession>
    <name>A0ABQ8VCI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2OGFeDO JBP1/TET oxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_771047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4481359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="28880" checksum="2B2DB5068B13FCE9" modified="2025-10-08" version="1" fragment="single">PLADGEHRVMVCMLDGPDDPTYQKAVENMTESILKAGQKTAWTSKEKKHKRGNFPALARGISYGKGQHQPMRLVGDRQPMMDELFQRDCFRRVAGFQNGAFATWFPKNYAEHLRLNSELDSKLPHLKRNFDNSVYLCMTVNFGPSTWTHIHTDSKNDVRIPCAITSGGKYNYKQSGHLILWDFKLILEFPPGATILLPSALIRHSNLPTAPGETRISVTQYTAGGVRRWLEYGGRTEEEFHTKDPQKFAEAWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD01</accession>
    <name>A0ABQ8VD01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_921822</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018287">
        <property type="entry name" value="Hap4_TF_heteromerisation"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF7">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10297">
        <property type="entry name" value="Hap4_Hap_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="54450" checksum="02B378E49F173F2F" modified="2025-10-08" version="1">MAATAVSSSSTLWATASKDWVIQPKPKPGRKPKNEVVIETVEDADGKGRRVQNRAAQRAFRERKQSQLAELQARIQLYEQGEIERNVALQNIAKRLKEENEVLRRENAQLKESLDAAERELRTIDKRHWRDASPTSSIGSGASTRKRQRIDDRVQDDALLSHLTTTFSSASPPSMASSPGSNDTSDTPFSPIPLDHHHLTAAHSSILNLSTTDKYDSYADHSVFMSCGFCSEHLPCVCRDAFPSSTDMVPKSEIFENTAPGIIRIGSPVPHGTPSILDELPTFQPAVPLRRRQAAASVKPVVLVPAPTCSGDPSNCLACADDSFGKAFCDALGKSVAAQASSGSTSENLSINPAEVSLGSHELIDQQPEGESISTSDAWKQLKSHPNVAFSDLALLADVVARRSKCTGPRVVISPAPGSITPERIASPDPLVNSPEKSNDSEAVVLTDPHALFRKQEKARSSPPRLVPQEILMQCGQERLRQVQAAGVREALRLLDAKYATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDD3</accession>
    <name>A0ABQ8VDD3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_921729</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="13"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="13"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="123"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="348" mass="38556" checksum="2848C2C19BF93AD7" modified="2025-10-08" version="1">MPKVKQSSASHKIPRPRNAFMIFRGENLELLKANTGINKPTQMDISREAGKIWRALGPEGQEEYHARAQQEKEEHARKYPGYFYKPRTKQQIADAKAEKARGKPIANAKRSARHSDDDDYEGSSLRSSFSPSSMGSSDFSAADSSPSPFHSGESWGSSSLDSGSREVSPYSNGAPPPFAGADTWILDPKFQASLAGYEVYNSPLESTPMATTFSQQQQQSLGTSMYSPTSDDELFKAAFDNLLSNEYFDPPTIASGSSAPEFNRFAFNSNQFDLSKNPMDFLSGSTDQNFPLINNVNTGGDVDYTTDLLPELDPSLVPGSYFQREELYPPQQSIDYQLECYRLPSFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE44</accession>
    <name>A0ABQ8VE44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_920380</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4491040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="543" mass="61432" checksum="DA620D8B1542892F" modified="2025-10-08" version="1">MDSSTNTTIQQAAVFNLVFVEDFVFQSKSTSLVIATAAIATAVYYLFSFFESSLRDKNGNGIPAGPKGLPLLGSFPFLTQYPELTLDYWAKKFGDMYSIWLGNQLFVIVSSPAIVKDLIVTNGAVFSSRKEMFIKSQTVFAGRGITATPYNDRWRKHRRIASGWLNQRAVDSYTPILDREATVLVKAMYQESKAGQVPINPQPHAGRASLNNMLSIVFGFRTDSIYHPLVGRALKLSREFMNSTGPMSNLVDFIPFLQNFRTPMRVRGEKLHQGLVETYGGFIKDIEHKMQMGVHVPDCLAKTMIDTKEEEQMGHLDMAILASAFMIGGVETTAAIMQWFSALIPAYPEIQRKAHEELDKVVGRDRLPTVEDEKNLPYCHAIIKEVERCHNPFWLGTPHVASEDFTYRGQFIPKDTVVVLNTWTMHHDPSRHPEPDRFNPERYLDDSLTSADSANLTDPYQRDHWMFGAGRRICPGMIVAEREIWLTISRMLWAFTMESLPDEPIDLKEYDGLSGRSPVPFRINLIPRHDKVAQVLGMEEAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEN4</accession>
    <name>A0ABQ8VEN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TBP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_765813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="315" mass="34432" checksum="DC86AA0100E0C9A5" modified="2025-10-08" version="1">MSFALPARQVTFGRSNVSAQQQQLYQQQQIQQQVQQQQKLQLQQQQAQQSGGLALPGGAYLQKPTNPAGPSPLSNSFQPSLQASHPQTNPVLAQSQTPPSTVGSPSNAVAGPSTPSAVPATPAPLTLEQQHITAVEGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIRDPKTTALIFASGKMVVTGAKSEDDSRLASRKYARIVQKLGFDAKFSEFKIQNIVGSCDVKFPIRLEGLAYSHGQFSSYEPELFPGLIYRMIKPKVVLLIFVSGKIVLTGAKVREEIYTAFNTIYTVLCEFRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF94</accession>
    <name>A0ABQ8VF94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_951846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="487" mass="56185" checksum="3E504568B64C4FF5" modified="2025-10-08" version="1" fragment="single">HRRNAKFYLPNHKIFVNTSGAGKTRLVLEHLCSSWGLYFSCHDDSHVGSEDVPSAMSNIRDALFGSTLPHAPNLLVTSADIAAHARDTDTNAHDVTEKDVLVKRIEAFKKDVPKSEEFRHALERNQQLAWSELLVPLLSRLLVFQQYVIALQRMRKDLSQMDHKRRWLHLQLHPHLLSSSGSEEDDPFNQLSNDLIAWFERQDIDLSERISIMRLLSKAILVWIREALGQAKTTPIYIVIDECQFAVTYIEDLFRSADWTARRGILRELARCWDRSLNHTARSGTRSSAFIFTGTGLSRELISDVLSSVVAKTQTLSSVYNTGAFDDFKAQAAYLERFFPRELWHTSGGIRDRIYYWLRGRQFLLIDIYRYRFTAEYMSLALQCGYQNMHQLLDQYINSVACFRPADFKIPEKDLFGIVELPSPAFEFEKLNERMRQKIKTIAHEYLFTSKLESHLGSDERAYIELGLARISGYDGQKSVKIDEPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFC6</accession>
    <name>A0ABQ8VFC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="110" mass="12111" checksum="482073E9D83C9615" modified="2025-10-08" version="1">MSTTLRFEILIFPCSGGTDDYHLRERLFQIPIEFADCANGSGTRMQEKFYSGNKTRNGKLPACLRYNVWEREAAPVRGQQRGSRGSAPPLRGRGGSVPSSTPTICTGDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG10</accession>
    <name>A0ABQ8VG10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_341592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046300736" evidence="1">
        <location>
            <begin position="20"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="132" mass="15026" checksum="65776DD3345B5564" modified="2025-10-08" version="1">MIMLFNLMLVWGFASQVCALPPPSTPARKMSTRLSSMFKPKPGDVQQLEIFIHYEVIGTQKLPKVDSMAQRLVKAASRSSATEGAETESLRRVQARVIRKRNCEVFIEDISKNELDVLMWNATHDVVYANWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG69</accession>
    <name>A0ABQ8VG69_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="779"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="846"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="971" mass="108018" checksum="70E18C33B19B0F78" modified="2025-10-08" version="1">MAMNSETLSLSMKTTTATLFSLPTEILEHIAFYYVCPRVLGPPVPLTALLLLCKAVSYKLSAARHLYARVFKYKFSFSAIRRRGFEPKAGEWSWQLRWWCEVLKGVRSRRRRLGSEPYMDNFDAEEAGLQETMYALWIMCLEDDGCNRVQMQLAGVYEWVEGYIRVEMYKTLDKGWPLANAGNSCAMWVFWYLSSKARLMDESTEQRESLIDLILPFLAVPFRYPSSFAPANHFRLPLRSSVPSSSSTPFSIPTPHGPFPIYLHPSRHTWLTPHFDRWTPLCTPLAADAAKLVYFSRRETMLFSVLDLLPRNREEHRARIRARLAAQGNDEVDEYQVETVLRSELPRPTQEDFEELNAGLLGGDMVPSSPFSKGGGTPLPRTHDPWDDARKTLPNLLDPRLHQSDISESHFDTAEQIFGGEIDESACSSRRWDADWWRLRLCRSAWVGQGGSESEDNLLASDVGTVTNDADTNIATDANNEEGEDCDDDENDEVMSEYDSDIQQNVDMPVNEEAEESAQVEQVDHDMQRNHTMLTGYPQKGAVYTPGSLNGLWTGRMIIPDETHLRALLLPPAPTVNQQELLLPPDQLPLPNNDNHEDEPHPAVVAAAQNPLNNANLTPDPRQEAGHRPLPFNEGTLGLVAVPLYVRLSEYAVYSGGRTVPCAHDTEDDNDYGTDSDFDGDDGIYSSTRSHNSGDGSNTTRAGSRHDTGSRPTNINPDDAFDQGIKDSWFPPNTTLSTKGDRVIASVPSSGPTNGEEYEYVAVRNSDINADDDFRFSPSVASTSTLTPGRSGAEAQRKRKPGTFHDRETCTGCIARERALLFARTEAQALVDIDLEHPADASSDGCSDEDVSEEEPTEDLPPYVPSAETIPPCNGIRDVLITGSTDPRHAAAWGKWVWRGRVRKWDGLVGLVRSVDSGPPGSSPVNGGGGKIFFYGTLLGGQNLVGTWRLAHEDPRMPAYEGAFTLGRKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGL2</accession>
    <name>A0ABQ8VGL2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cerato-platanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_330071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22778">
        <property type="entry name" value="DPBB_CEPL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047441224" evidence="4">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4493381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="14805" checksum="25B6FBFC4E4994AE" modified="2025-10-08" version="1">MNFFTFFVTLVVAAFTTLVAAETLQYDTTYDDASASLSTVACSDGSNGLLTRFPTFGSLPSFPNIGAFGAVEGWNSANCGTCWQVTYSSNGVSTTVNVLAVDHAGDGLINVSEEAMNTLTNGNAVAFGAVTVTSVQVDSSACGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH90</accession>
    <name>A0ABQ8VH90_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_312108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="24810" checksum="825DC8AA9DA01E58" modified="2025-10-08" version="1">MLFTGLKGCFSPLISASILSDWVRNGGSIMRSEREFYNTSCFFCAGVDDPWVKGLSEKSVTVLHASWVSRCVEKQFSMPISLFVLDEYFNSNQIGLPSSPNLHHSSSWTDASSSHSASTTLEPSEPVLPLKRRFHDMNSPNQENDYSPARTRPKKRQRILHTSDVNDPDNDFAELPTVSIRNLRPLANSVSKNHFLPIYLLVLVYPFRLSRFNRSLVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIG4</accession>
    <name>A0ABQ8VIG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="26983" checksum="E4037FFDCA1044DD" modified="2025-10-08" version="1">MPLTRSQTRKKAAQAQVENENPTGVAPYPASTLRSPLRLKRNVVTPASTSLPSTLTPKDRQTHRRLERAMSQKLLQAMADTKVKVATAPRVCNSGPKPLRRYETPLELVGKAVNDPALLNAPKANRVYKPRREPSFAAVLEELSEHDTFQPVRPRQQQQLTDLPDLEEFGGIPSNSSYELTEQEQGWMKEFDETLPFSFDDPENWGQFRGFMVNFDEFMKRKIRDQGIETTHSGKFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIU0</accession>
    <name>A0ABQ8VIU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_980980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34450" checksum="C037B624BAD8651E" modified="2025-10-08" version="1">MGLILAHENNILLERWSRLLCNAPIDIARTILEFAAHLDKTTARSIALVSKDANAWVTPILYQTVVLLTDTHIKLVESGLPSFKYTKTLILSTSSIPDPCLLKQSCPTLRQLHIHKDIAWEVSKKYPIGVLPTRLHELVVNSFTQPAYSFMPLYSVLTHLTFVHDIPRHFPETPAEVFPNLTHFACPYFVASGRSLIPVHETSAMLASALAYTLDKVLSIPSLRIALVLVKDFSQNVTDSLATLSDDEREAHMHALLKDVPQKDAPKVVLIARKGSMFYSDGREPAEAWDTTGGISYWAEAEAALGSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ09</accession>
    <name>A0ABQ8VJ09_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA polymerase phi-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_881172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYBBP1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007015">
        <property type="entry name" value="DNA_pol_V/MYBBP1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213:SF2">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04931">
        <property type="entry name" value="DNA_pol_phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="662"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="735"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1174"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="743"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1174"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1185"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1223"/>
            <end position="1233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4495629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1263" mass="141310" checksum="2A6CE353F10B64D5" modified="2025-10-08" version="1">MSTTLPLFWHLSSSSKKDRLDASVKLISSLEHFQAQFEASSPSEEDEGSDEKPDALETLNAQDVSYSVRRLTRGLASPRESSRLGFSVALTELLSRIDTVTCSQIFALIMDATKSQGSMTGQEERDVLFARLFGMTAIIQSGLIVRTKPLPTSQSSATLASSFEGYEQVLTELLVLGEKKSWLRESAWWAISLAADSLNAAEVRWKDEAVHATAQHLFVENRIWSPEKIALALKLQSAFEEFNWRPLFSPTFKNPDLLSNVNLQTLALILKDSNNDGGDADAPKTAAAGGWKTQLHYVWDIMLDRLLNTSNAVNSNFPEFFRIVVDESLFSSTASPERKYWGFQVFQKALHLVSEDNMPMLFTKNFMRTWINHLSKQDRYLHKAAKQTVAEIQTFVQRNPTLGFALILQLTGFHGSQQFDKITKTKMVESIISTMAADDIKQYIAYLLNQANDGEVEVEIINARRRWIIDQLSALIQNGSIAKTGEWVESVLDWFVVNGLYVVKKKSEKSRFIGLRQIPKPQFSDELRHACRDKLLSCLADLTNHITTIESDNAKVKIAGVAADGELWVTKVLSTIEELKQDTKHVSSIAEIDEEEEVLRAKVREVVAKLKKVSGNQQEAASGTQLLLVASLVQQSCSEEVVSLETIELCTNAATREFSLDKVKKKTKKGRPPASALVDEEDSDDDGPEPIDAIVDTIIGFMEKSTAYMRSIGNQVFSLISGQVKSSTIDLILTQLETRDPAAEDEEMDEDEDEDEDDEDEDKPTNGEDAEDGSQSSDDDEEDDENENSDNEEVDEELRQRILEALSVNGIKAANEDDEDSEEEEYMDDDQMMAIDEHLAEVFRSRVNEKKASKDLDAQREATHFKNRVLDLIDIFLKKQPSSPLIVRLIIPLVDLITRSTTDEKQLSDKARGITRSRIGKAREFASAEEKKVEGGGGKEEGEGEEQEVISIFEALHKRARTERSPDHLSILSDCCIYISEVMLHAGMQDQVVLQYRHSLIDFISRKNSSLNVSFFQQFFRRSRTAAWNLRNDLLEVSGKAANLYRQFQAYQLIHDLLTEPPFDIHHEVTQYLQALCKTLLDVIFRTCDGSDDSLGLNASQMREVLRLALVGARQARKVAVAAEDAAVQIPQPQNVVATIWDSAAWTRATDLLLASERFKGAAQMCKQVVQIASAPSNTSQSQSKGKDEKKVNPKGSKESNERLMKEEEKKGGKEEGGEVRGEKKRTSRKRKTPAAGADGIEGEKSAPSLEGQGKKVKRKKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ88</accession>
    <name>A0ABQ8VJ88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_267927</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="271" mass="31193" checksum="2463E9773C580675" modified="2025-10-08" version="1">MMCRYGLVAVVMDVCKRIFLYAHDHARRPRIEQDHRSQTCKAWISYLNNSLQMQRVDHKVGLGSKAECYTFQTQICVHKSSYATRLTVSTPLLPRVRTLFAACQRLIPVLFNDLHHFGLALELERATSIRQTTRRTMLPNERSTTYIYLEALQRSCFFFTDKMPNKLRQMKGQIQMGISRVKHHAARHSHYWSYDHYSRATVSLIIGASSNVALKVTVSVLTMILFGQVGNKHINQITVLSFVLLSSQDPWLNSTHESRIKGAWISVLIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJJ8</accession>
    <name>A0ABQ8VJJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_263802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045750037" evidence="1">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="180" mass="19443" checksum="4166D497128A6AEC" modified="2025-10-08" version="1">MKLLTTLITLAFALSVAASPTRRDTSICAGEEILSETYIGEEKNVRLQHITCPPTPAKRALAPRQTNVCGNTCITNCFVPSGGGPVPDDCHVIADALRFDSENVGALFEIGTGVNNTIALTYATCESFYVNQDPTTQIYCRTDWAAVIDWVAPNCQSTQNAHGGNCVATDQQFFIQVQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJL4</accession>
    <name>A0ABQ8VJL4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_918396</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF4">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="36"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="400" mass="43594" checksum="3F42B8D8AE04CC2B" modified="2025-10-08" version="1">MSLPTIINKRAPGVPFYTPLQSPPAGSARSKAKTLLFTPLKIRGVEFPSRLWVSPMQQYSADNGKMTPWHMAYLGGILIRGPGLTFVEGSAVEAIGRITPEDLGLWDDSQIASHQEVVRFAHSQGQKIGIQLMHSGRKGSCVALWLSFSAVATPAAGGWPDKIVAPSAVPFEPGYPVPHALTIKEIEEVVVAFKNSAQRAVTAGYDVLNIHAAHGYLLSEFLSPVANKRTDKYGGSFENRIRLVLEVIDAVRAVIPDTMPLVLRVSATDCLEQENYPSWKLPDTIELAKIVREHGVDVLDVSSGGQSAAQTINVFDIQSVYAKQVKDVVGDSLLVGCLGGITSGKVAEKYLQEKRGDMCFVGRNFLEKPGTAWDFAEELDESVHMSKQLEWPFIGRGKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK68</accession>
    <name>A0ABQ8VK68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="38291" checksum="D944E4FB83AD2D96" modified="2025-10-08" version="1">MDEPVPVQPSPFADQGLIGTFPPPYQSQAPSTSIIQNQPQPSKSPQFWDSGIMVVFSAELPPHHTILYRVLIDSLRCRSKVLDDIFGIPPSTQSQTQGTEVNPIALPASITAEKFESFLIGWNEFDDKVAANILNLLDISALLEADGALSYAMSKVVGLNLPAPQLLGLAWRHRAHPQVRDWIEPAVMGLLSTPLRCHNVEQESSIGLAYPIIAKARERIQEARLVLAAIPFQLAPRDILFPECPDELHQYCEKSWLFFWYQNITVELIHPTKPPLSYSGLVQLVEKTKFENLQEGCKSRTMECMKSYHDYPTVPDVFHAAVSDIVQLFNIPHEIQIYLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLG2</accession>
    <name>A0ABQ8VLG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_828452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="451" mass="48189" checksum="6C26823CC22D4773" modified="2025-10-08" version="1">MRMALRILFHLLHRPSIISHSAIFTRRSKLSFNMNVSTNTHKDILIIGGGIIGCSTAYQLTRHPSFSSATTTIKVIEASKHGPAQGASGKAGGLVAKWAYPKELVAVSFAEHVKFAQEHNGQDRWGWRFVRCGSWEGKGAVLDEDEEFGDGLGAGGQRKSLEKTLGLGEGTGHKNDPASRKRKGLPDDLLWVDESLTHTYSPMAGDGDTAQVHPLLFTNSMMELAAKKGAQLIAGRAIKLNISDGVVTGVDIIHKDSGKSETLRATHVILAAGAWSSSLLESLPISSTRAHSITIHPQPSVDIAPYVLFTEISLPGRRGLTVSPEIYARPGNEVYACGPGDDSFLPKNVDDVTIDEAACESIWKHVCGISPELRAGTVNKRQACFLPIVETGGGPIVGAASNIAQGLIIATGHTCWGICNAPGTAKALSELVMDGKIQCANLQRLHPSNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLU0</accession>
    <name>A0ABQ8VLU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="204" mass="22396" checksum="2394F1EEA047D5C1" modified="2025-10-08" version="1">MHAIVPSSSSSFIHPTYWPRASNSALNDAPPLRLNSPFQLASSSQTVETTSEKLPSHAHQRRRHCVRVDCPVQSVLSSSSSHPFDDLSWISAMDSSSEDYGLSDIADLSELPIPTSVVEEAGSGAGPVRRRKTSLHRTSPLRVASGSSTHSTHHPSILRNRHVLAQSTPRPRLPRSRIAFHDLMPLFTCDLHKYRSSNPSSPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM40</accession>
    <name>A0ABQ8VM40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_918579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="184" mass="19929" checksum="7C12EA870021EFCF" modified="2025-10-08" version="1">MILRRASAQPTSVLVSASTTTFHATPLSDPTTAAFDVSRTLNPAPTNSAAPEPVPMDPIGASLLTDRPDLVFAQEAYNYMECSKEILQVQTETLVILQQKLNSMNEDKELGTHTFFPVVTPSVRSVSANTRLSILRNDPQIRMELRSSFVAQPAQPSSFTLLHCISLSGLIDVSSGDNRIGALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMM3</accession>
    <name>A0ABQ8VMM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_917355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF213">
        <property type="entry name" value="DEPENDENT OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="530" mass="58506" checksum="7F9FE9F665A4203C" modified="2025-10-08" version="1">MDPVTQHRISQSPGIPRPSPTRSYWAVPPSNISQWGAQDVLPEKADIVIIGSGITGASIARTLLRELGENSFDVRIVMLEAREVCSGATARNGGHITPAWYHQYPELVKTYGKETAHEIIKFQVSHVHKLLSVAEEDGLLEDSQCRLTDSFDAYVDRTRFEIARENYTEYRKEEELSSLHQVTRLYEDKEQLQALQLSSSFSGVIGTVFGTMHAYRFVTGILSRLLKSHTANFQIFAETPCISITAASSTYVIETPKGTIRSTHIVHATNAWTSHLLPGFRRKIVPLRGEMTSQRPGTGLGFGQIPPSLSTTPSSSSNWQGSRTFIFYTGGKDGIFDYLTQQMQPCKVSSASKYPLPRTELMFGGGLAFNPELFCTQLGNTDDTQNIPELSKYLSSVLPCYFGENWGDDAESSEEDDRLNWGKGRTKASWSGLIGLSADSNPWVGRVPASLAEGRKLEVDKSRAGLADAGEWVCGGYSGEGMVNAWKCGAALAHMILGRCECPEWLPEPYTVSSERHAKAKLDDVLQSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMZ6</accession>
    <name>A0ABQ8VMZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-rRNA-processing protein RIX1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_737180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RIX1/PELP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012583">
        <property type="entry name" value="RIX1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105:SF1">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08167">
        <property type="entry name" value="RIX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-rRNA-processing protein RIX1 N-terminal" evidence="5">
        <location>
            <begin position="9"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="602" mass="66700" checksum="0852E4B5F377AFD2" modified="2025-10-08" version="1" fragment="single">MDPTHPLKALLNFHLASDASAVVHLPFVTGVITAQHFLPSPHLAKWTSRINSLLHSKDAGARWAGLCLAHRTSICSKLVMIESAQSWLGVAIPLLSKKEPLPNLIASINLCRMVFRNATDTPEFQRQVSTPNVSKFTTALIVFLENDSDLELKKLVLKTLARLIPLYPNIHRASHATLVSIVSRIFFQSAPNHISQQLVEPACLLYSVLHYTGGKVGAANLWRKSLDDSISSAWTAFICVRTTFPDENGRFPQVQLLHEEPATSVTLNMERLCMYIQVIGNLLQSPTQRPVQVPVGSLMNLASKMLLVTVEDEAPSNIDPIVRAMETVVIPRIWRAACDLIKCLCECIDRHLTTYSSRLLSYIAFRLEQKSSLFNQTPFLETVHALLTRCHPSHSPLLSSRLTRIALSNLMVILPSQTDVQSSMAQTDSANRSKKGRKRARNYEGDELFKASGDVICPTIDDVKSLLISCDVLRLLLQNANVTPALHSMASRVILAIFLELPQMTPATLSPYPQAHHAVVQKIRDTAVQLGSSTTSAMSQSLNLVLSATSGTDDQDSLREVDMLIHPRFPPLLRPLPKIDSLALFRSEESAEEAEERQHLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN86</accession>
    <name>A0ABQ8VN86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_941859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="256"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="351" mass="40075" checksum="E25EDE6C36044E5E" modified="2025-10-08" version="1" fragment="single">LLDAFRAHYAQFQAIVVQVHSEPTDPFLLQLLGEDLNQFTQIVTEHIAIFESEEAQMLQNSIQTMILDIRALYNQRIDTSEISSFLDVSRSTLRRRLLEYGIASPGADPFPSTAGLVGDTHGVINDHSDNSDELLDAEVPQPAHLPEDVQAEASSIPSSSSLGYISRVSDEQLDSLLGCLRIHYHQAGIRILDGMLRCLSIIVPYECIWQSLIRIDPVHHVFDCIWIRRRGYSVPGPNSVWHHDGHHHQYLYIVFHLWVDVSHYISQTWHDMFTLLEIRHGLQVSNVNHIWLLQHLFLPVINDQLAFWAESWNSHQVSQHHGPAQSPEDMFVFDSLVRDPRGVIGPICNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VND0</accession>
    <name>A0ABQ8VND0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045161575" evidence="2">
        <location>
            <begin position="19"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="318" mass="33437" checksum="58B35A3DE4330D7A" modified="2025-10-08" version="1">MQLRLSFVLLGIAAAGSARPIVVLPSSQVLPTNLATTSTSAFASASTSTQTIISPVSVLDARQIYVPSLTQYLEDRSPAVAAPLITRAAKDPSSQMEEAYEHRVRSSLESRAETRGNVEPDVPISKRDFFEWMGKKAGQVTHNPGLQQIGGGFKTIGGEIGNKAKQEDQKVKNAYNNAGAGASAGSAQPQPQRRQEANPNVENSSIVQSAERIAEKQQQMQAGASRLKHIITNPFHKAHDRMKQGAQNIHDGIVQKKNDAVNGAKNVEASTVNGVKGAANSVVNVGKGAANGLKGAVNGAEQGYQEGSNGGNTPAPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNE9</accession>
    <name>A0ABQ8VNE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_171658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045278488" evidence="2">
        <location>
            <begin position="19"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="215" mass="22438" checksum="D37505808A6FDBEC" modified="2025-10-08" version="1">MQLRFSFVLLGLAAATYSRPIADSPLQTREGHSTTTFKATPTVALDANFEHPRVAQSETIVLTSDPTRTASLTKHTSDVAAETKATSSPPYPRMLKSKRFLEEAAHGLSNAAGSIQNATDNFEDEKHKYTQPFTDAGAAIHNATSDVKEGFEGLGDGVKNGTENLTNGVKNSVEGAAGKMKNGTESVVNGVKDGAEGALAGGKAGWNNAGPDSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNQ6</accession>
    <name>A0ABQ8VNQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="10">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_822519</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="10"/>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="151"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="454"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4497516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="760" mass="84977" checksum="93FE561216EFA8ED" modified="2025-10-08" version="1">MRNKSSRKRVPSVLAGSSRKKIKVEHDGADSLPWTTVSRPVETALDGDDGILELEEVEGVEVTYEETETGRVARFNFIGVDEARREEEEKAESSEEPVTGEGEVDVVVEAEHFDSEELLPNWHPYDLHPQLTRCLHHNNFLNPTPIQAAAIPVALKQRDVVGVAQTGSGKTLAYGLPILHKLLLAAPQRPLSKHRPVQALILAPTRELALQVSTHLNACLSICNVEIEHVNHKYDGISKDQRKGTQQGNLKSTAKKPPPIVSAAAIVGGMSVQKQKRILDRGADVLVATPGRLWDIIEENETLAKELKRLRFLVLDEADRMIEAGHFAELDNILRLTLRESEEDRIPDDVPSIHGEPGLDVQDDKEKVARDQMQTFVFSATLSKDLQKNVKRRAKPPRSKHPQKNDKPASTLDDLLLRLDFRDRDPEVIDLSPEGGVVSTLTEGKIQCLSADKDVYLYYFLLRYPGRSLVFLSSIDGIRRLSPLAELLNIKAFPLHSQMEQRQRLKNLDRFRSTPNSVLLATDIAARGLDIPSVDHVIHYQIPRSADVYVHRNGRTARAMRKGFSMLMCAPDERKVVRALLGNLRRQEDEIQEMSIDLGMLDKLKSRVQLARKIETTHHKSKKAKHERTWMKETAEAMEIELDSDFASDSDGDEPNKRQRKADQATAAALKAQLRQMLAQPLIARGISAKYITSGSNHIVDELISGGYNEKMLGVGINDAGSDLSKAKAKRKKRDPIKGLTKDVSEGEWMGINIDLAMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNX4</accession>
    <name>A0ABQ8VNX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Grap2 and cyclin-D-interacting-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_866334</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCNDBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049318">
        <property type="entry name" value="GCIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20936">
        <property type="entry name" value="GCIP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="7">
        <location>
            <begin position="63"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like C-terminal" evidence="8">
        <location>
            <begin position="222"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4495532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41051" checksum="7A3B90DF5E8CBB98" modified="2025-10-08" version="1">MTNNDQQKGKSLSISTCSFAQVVSAITAIEILVETCKAARDSLFDHPQSTEDPPPLPVLHQDLLSLLSLVYGSVTKLSLALKPSSPTYSACLVPLQDLSNYIAAISHCVSMFDASVHGTTLAKEVASVAIDVVETVQTLATVFLQIEGSSERPRTGDEYLVRTGAVHSVIDIARHAEDGLSENNLTAVRRLWFKDAGALEDGVREVVEMIEDVQSGITTESEDGWDELGLEPSQPLTEQELKVAQKVLIILRLCNILHQRVISDILSTPTLPSNSSLDDLAPLSPALLGTVDELISALDSPQDLDSVTTELNMLKGVIDDIRNRLSVLNNQPVSLVTLLQKTSLNEVTVSTNRNSRDEWFNACFDQIAKAIHSAAEASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPF3</accession>
    <name>A0ABQ8VPF3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Leucine rich repeat domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_818591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="614"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="614"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="803" mass="88075" checksum="498E871BB953EA35" modified="2025-10-08" version="1">MQNEHGDDYIRRIAAFIRGNERNLAELGFVRRRNPRRPAETNGSAFYNPLTWFGSESTGPPPKSVVMSIDTHHLFYLLMRLEALNLPVGTLDVRVDSPSRPLSYINLFPDSDKTETLSLSSFRSTFSAVSALSLGVGWWGRPEPPKVDTELKYIYSSFTKLPALSVTAPTRNLIAELANEPPNENAIPMDSFKNLQSLECTDIDPRSLLGWDYLAESLISLRIKKSGLEDVSDIFIGAVLDDQARRAGSASRKRMRRIPYGSERHTSFYSAQLPDTVQEVADEETSSPTNYIPPTTPPELSSRKWASLRFLSLSGNDLTFFPTELTLYLTSITHLDLSSNLLNSVPEGLNALYNLVSLNLCDNMIESVLGIYTQLGSVTSIDLSRNRLESICGLERLHALERVDLRHNAIEESSEIGRLAPLPNISNVWIEGNPFTEYEESYRVTCFDFFWKEGKTILLDGSPPGFYEKKNLTAPLPEQAHTSRPVSAAHSPPTIAIGHTHPHSHPHSQSNSPPAEVNDGSNHSPTAAPLPALSSTSPQLGPVGAVGVSGKSRKKKVKRIVDLDGDHVSEDSASIKGSNHKRTTSNGSYAFKQVNAPQPADHPSFGQFISLLATPQNLPPTTSSTGETQQPEASTSTATTRLESSSSPKQSLPPPSRTETGFGSGTLSSRTKRRPRHTRYQTEFALPTEGDSADSSPTLGPIDGDRFAILPSSPAVPSFRRSRNSQTFSSAKSSARRQRVSASVYEPPTGGDNDSDLFAGEQPNTIVDEAEAFRRRIEALKQDMGDGWLKIFSQTQMKTPSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPG9</accession>
    <name>A0ABQ8VPG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_145180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="51"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="40230" checksum="D5A4564E8C69292C" modified="2025-10-08" version="1">MEDFVQSNYVNEVKPDTDSIMEQAIGPVDVSDVLLTMGMTDVIVNEVDMLYYGDLAIGTPGQGLTFDVDTGSADLWVPSPWCGSSKNHYDGSQSSTYVEQDRRFAVSYGSGTVYGTTASDTVSIAGTAVLNQTFGVVYRESQDFQEYPNDGILGMAFGTIAQSRSSTVFETMMKQGKLKWPCFSIHLARGQETGSEMCWGCFDPTKATGPISWFPVSHRAYWSIPMSGFDVASERTTFDEVIISAIDTGTTFCYFPESVAAEIYAKIPGSKDASTTYGSGFYTYPCISKVEIGFLFGDSTFKLHPDDFNLGMSMYNPAECIGGIFAMNAAQWPTNLAIIGDEFLKSWYSVYDYSNGGRVGFAPSVNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPH4</accession>
    <name>A0ABQ8VPH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="282" mass="30321" checksum="DF2CDC5AFF91FEA2" modified="2025-10-08" version="1">MSQPIQTAMQNPQNLCDYCHVKPKFGQFNYCSKTCAAQAPSRININAPVSYNKPATAAVKPRAQPAATNMCDFCKKVPKHPGYDFCGKSCAQSAKTGSSTKPTFKSPQTSSAPNKPNPSNKGSFNAIAQAATALVGSTPAPIDPTQIANLVVQQLQTLLPPAPSVYSTSTAQTTSLSSKQTFQQPTSNAQPSLRVQTQQPESEAPVECLIPGCGQPVYVDAKGTKTSAYCSLRHRQEAVDSGLASPCIFCLQLPQSEADYFCSKECREESLNKERYNEIVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPL0</accession>
    <name>A0ABQ8VPL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxin/Dysferlin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_818774</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxin/Ferlin" evidence="7">
        <location>
            <begin position="221"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="340"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="426"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="461" mass="51289" checksum="6A8180FD6FA44485" modified="2025-10-08" version="1">MPSSTTTSLYEFTSTVPFPLTAVLVQLAPYFALVKNAFEILTWSRSTSYDAWLALASWWAVCLLSKATLRYFLPIAVVISLTVITASANARSSAPPVTETNLQATIADLTTIQSLLPDAKFLPKSRPAFSTLLRVSAIMYPPYLLLTYYVPLRILIAVTGTVGITWNSPCASVLRNTLLKSAWVRWCTLYVWSKVTGRPFPLRNLSYQTLATLNSVEPGLSLRFLFTIYENQRWWMGLDFSPALLPGERPSWCSVSLQPVSPPNAFVLPEPTSVYLRDSNGKRVKRTATWKWEEPEWRVLVRKEDGVVSRVEKPVPAPKEENSSLLMKAAGKMKDVNSLQSLANGEGDRPSSEKDEDESEDEDIPTDVDGWVYGDNKWEARSSKGGMGKYTRYRRWTRVAVVNEVVEIVEDGETGVEGGRTTVTMVNASPISSPSRQTEANSEAESPLRQRLKSALSKGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPU7</accession>
    <name>A0ABQ8VPU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_894816</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="167"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="379" mass="43749" checksum="9776C3F45748CA36" modified="2025-10-08" version="1">MPKLHLKRTPEEEAARRVRKLEKREAKRRRKHDHYGHGSSSSKRQQRTAVVEEDNSCDEEDGEDFIGPVPGPSNYQPDYETIRAEIEEQRFREKMAMAFDDDERLDSIEARFNSFAHVPMHWGGKNSSKPRINYDNDDFLAVDPMTMDDEEYAEWVRMGMYRKTHAQEIAEKERMKAERAAKRAQEKAIRAETERLQKVAAAERWSHKLKKEDKRLELLRLEYQNRWKLLLSNTQPADITDIGFNDIPWPILLAYKHKSDKKSVSDTVPSLSLDDFTPDAISTFLFTSPPSANTSIDTDIDVAKASSSSSSASAQRLSEAETENPKKGRKEKLRETLLRFHPDKFEGRLMSRVRPEEKEKVTEALGIVVRVLNDLMGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPX1</accession>
    <name>A0ABQ8VPX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_819106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="6">
        <location>
            <begin position="9"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="664" mass="75273" checksum="23F320DD6098F4EA" modified="2025-10-08" version="1">MERVQFQQEQMLDELKDLVDKKVFTVAETKQIMKQRSIHEATLVRRVAKKSDFLRYASYEMGLEHLRRKRVERLKIPKTPVTVSDFALVRRQFHIFERALKRFKSDVGLWIEYIQLAKKEGARSLVGRITARALQLHPNVPSLYILAASHELAHLSPSTARTLLQRGIRLNSSNVEMWTEYLKMELGFIESLRRRWDVLGITREGTGDSQNVKNIVSEKDQFTDVDMDEGTTTAGTVKARDAELERLDQEGDEGTAARKQILDGVIVKAVMDSAVQALPRIELFESFNRLITIYPSSPTLRGSLIEHFDALLRSTLPQHPRAIEILYTRLLTSASDVASQASSSSNPSVENLRGRALVEGVRRANEMLISIMSDTQEESVCQVYAQFALGWCQQDSRINLDENLKLYVLSSLQALIHRQKSSSPSLLCAHIKLVTEAAQRGTIEPAKALDTAKRYTSRVPESASVWIARLTAMKALDENIDAVWREARRSVSPKDEHFAHVWTWGISEDMVHDERLRVYEVLLNESVGDSSLQEHLLLGYVAALMVSRSTPISGDDSDQVANKSAKALNLQKLRHMQGRFLNTGKVWQKMFHLEAEENGSAIVLEEIYELWRTANVVEATIAWAEWLLKNGKGKEASVLIVRSKGSVGQKEQEEMETQWVRIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQE1</accession>
    <name>A0ABQ8VQE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_818191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="232" mass="26479" checksum="F6C524E89E6C9897" modified="2025-10-08" version="1">MCSYLRTTSPYRIPSLSASTIGQSMKSTRTFSSSNSNLKIFWGSSSVTSQAIRLRGSRHINKILISRHSGLRCMSNSRPESGPEKPTQEQLRHQATTEIIPEELRLIGKIRQKSAPMRGAFIMAWRLFKILLFSSTKDQDLSKSLKILQNSQTLADRTKKDFRSLMDFDDLLQGAVVKYCRNTSCNDEITIKGNVDPLLIAVRLHRLRKSMEEMQDLEKLVREQMKELVGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQQ7</accession>
    <name>A0ABQ8VQQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily MFS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_822579</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF17">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="694"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="736"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="775"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="483"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="497"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="562"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="860" mass="93080" checksum="72B91A3F4AB381C0" modified="2025-10-08" version="1">MMNTPKSNRHSTTPRRTFGADDSALDDTDTTPTRSALRRAIPRISFGSLHRPSFRFKNSSDNEDGAVVSPTADKAPIPSVTQPAPEVYATPLPVLSMIVLSITLLGEFLSANVSTPFLLFMVKGFGKITDEAEIAFWTGVLVATFFLTQFLTSLLWATIAEKHGRRSVLIVSLLGSAVTCAIFGTSTSLQQAICVRLLQGIFAGAVGVARGSVAFVTDTSNEGRAYAILGFCWGLGGVVGAIIGGTFERPADKWPGVFSEVPMLVEFPYLLPCVMAASVTLSGSILACFLGPDGGPRGGAIQLPHEKNYDHSTIPEEDEESMPPSPVFEDQDHRDTFTGSLRRSIGKRLSGYLGTHVPDTLPSLESPPPQQAVPMSTGTRLERTRTVSNSKPNRFDGSAYGYGSHRNRLASNASLARRFSNRRGSAVSYGRRGSNNADGLPLRESFVNDMNFAQRLLMANENAVTNIADLWVAAALNVDNENPFESDSDVDSNQGDGDSDFDDPLVDFADDDIPASPTTHRPRRSSRPSVSGSSHRPAIGSARQQPLGSPRRPSVPTRAIPNRQSSYSSMSDYGTPTSRRFSNVPSIFSHPGVRTPTAVLDAQQLLLRDEEAVHAVPADMNENQNLEPILESRRASTIVPDENEVLHEKPPSLSSQIPILVIIQYGLLALHSTTHDQIFMSYLVTDYDSGGLNLNAGHFAQLIALMCLAQIFYQFYLYPNLGPPRGRFSHLTMFRLGSLFFIPSYLSVILYRVPFASEQEDGNLPLMTALTISTALRFCGGTFAYTAISILLNYMTPPDAVGFANGIAQSIVSLARCVGPVMGGWLWSVSVEGNPNGYPLGFIVCAGVCSLAVLHSLFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRK5</accession>
    <name>A0ABQ8VRK5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_915666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="3 7"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF61">
        <property type="entry name" value="ALPHA-GALACTOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046066178" description="Alpha-galactosidase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="9">
        <location>
            <begin position="331"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="436" mass="47858" checksum="C2F9588FDAAD2C6C" modified="2025-10-08" version="1">MLGSASLFGLLSAVLCTSFSPVPVDALNNGVGKLPALGYNTWNAYGCNIDEDLVLESAQLMVSLGLQAVGYEYVNIDDCYAEKNRSASGDIVADSVRFAHGMKNLTDQIHELGFKTGIYSDSGWFTCGGYPGSFQNELRDATTFQDWGFDYLKFDNCAIPFDDIIREGMIGKYTRMSDALAQLSQSSGQPPFLFSLCQWGWEQVWLWGSTLGHSWRVTGDIAPEWDSLALIINFNSFITQATDFYGHNDMDMLQLGNGGLTFDEAKSHFTAWALMKSPLLIGTNLSAITPDILGILTNTEILAINQDPIVGKSISPFRWGINPDWTSNSTSPAQYYSGPSENGTVFMLLNTLNETSDMFFNLTESPWIRAGRQYSVRDLWTHTENGTAVRNFTAVDVPPHGVVALLLDDAGDEPAGIFPPCAVWFNCAYENGTAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRW9</accession>
    <name>A0ABQ8VRW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_819736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004354">
        <property type="entry name" value="Meiotic_Rec114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03525">
        <property type="entry name" value="Meiotic_rec114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="43438" checksum="B21EC7C218358F12" modified="2025-10-08" version="1">MSHSTTTTATYTLVKYSRSYPNSAQDANSEWQHYTKPTLKLILDVKKSLTTGELESVFLRIVWSMENSYAQDQSEVSFENFDLLSFSSFSTRQTDRQQGGLPLKAVYRDSVVGIRYVNASNGTFRRFQITFSSANDASQFIDSISSVCPCKANSTAGPPNIPQMMSAPSLVPPVLHHPIAKPPILNNSAYAQTVPISAAFPLSHMHNNNIPLNQTDVFFPVTPSQRLSTYPTMHFPYPGAPYASVSGMPMPSSQMLVDHPNQIPSSSPLLPPPSSQPPFQFGGSQAHSQSAPFTPTPTQSEHPYYSQSGSVNQQVAFSQTLGNEIIKPVKSKSKVESSEKEVQTTDPFVFALREATSLYDMPRHSLEKLVGDVVREDGFVHLVSTLNRFFTTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS40</accession>
    <name>A0ABQ8VS40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_864330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="214" mass="25005" checksum="42D9D980DF841362" modified="2025-10-08" version="1">MFIPYSEQDKQLNPTGNAWLQDRIVAFQRQRSPLSYAVRQTVVKFNDQMTEADKKTVVKHFIPWIRIFRQVTTNILTHGDQSGRGMTRAQSIEYLNWLIEKLKINQTQLKRPDVNPKHDRYSYEVWISWAVDTICDWPENLFQGQSTGDGGGNKVDVPKSLYTTPALQQRVQEARTKLKEFIQGLDVEHEIGDAPPIMYEEYIPGEDEWYLPYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS53</accession>
    <name>A0ABQ8VS53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_55240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="107"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="30373" checksum="6225FF4096D1104B" modified="2025-10-08" version="1">MHAISTSSGESASGHRYHHRRTDSKTSSSSSSKMDGYSSDSHMLWKRKVSHDGDDSRPTYAGDGKPLGGYRKATPSAVPMKAEAIALNWPLREPDRSPRKQRISICFDVAFDPRASKGVTVPYDIDIAHRRDMSHTDIRLPASTHCILTEMRIFIDSEEFRCWPIRVKRKEGVRCVDVYEAIYKTLQHRLTDDDVRTFGEARIQRCWNYCLQRCIDSPGLPEYNKQRGIRRVDLLRGRRFFRGLVQSGDDWILHLDDYSGSSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT95</accession>
    <name>A0ABQ8VT95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-terminal nucleophile aminohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_29694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01908">
        <property type="entry name" value="YafJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052373">
        <property type="entry name" value="Gamma-glu_amide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187:SF1">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="330" mass="36968" checksum="9AA18306923A3465" modified="2025-10-08" version="1">MCRFVVYKGTSPVELSHLLTKPCHSIINQAFDSRLRLDRRRPMNGDGFGVGWYDSVYDEESYQPCIFTSITPAWNNVNLVRLAEKIKSPLVLATTAGSLSLDNCHPFVHGRLMFMHNGGIADFPLVKRRLQADLPDVAFNKVQGNTDSEWAFALFLSKLPDPNAKSFTTALLRDAMFKTIASLNHYAEEAGITEPSLMNFCVTDGETVIATRYISSKTDEAASLWYSSGTTFSEFGGGGHYKMSKADKRENIIMVASEPLTFERADWMEIKTNNMVVVTPKMNLLQIPIVDKFYVPPSDPASLTRTTEFAREKGLLVPRGMETMESEELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTE9</accession>
    <name>A0ABQ8VTE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AEX-3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_754080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF31">
        <property type="entry name" value="DENN (AEX-3) DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cDENN" evidence="3">
        <location>
            <begin position="368"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="830"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="701"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="835"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="897"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="960" mass="105032" checksum="A50F1B3B4652E641" modified="2025-10-08" version="1">MEDDFINISRAAGADLHSSHTGNKAARVLGLIQPPMSPVLASGRNSIVSTRSARDALPSTSITPSLPLASLYLVSGLPKSPHTWTLADPDAVLGLHHSDGAVNRWWRPEVLGSTVSPGAGGGKKKRRGKGEELKGAGALSKSEVGKMLSKALKLSFCREVEVIASTLQPASTVHTFTFTLPAPNTPLGPTPSGDLLRASVLSDNRSSVAPSFSHPYYGDPFARPSTTYLGGPRPGSSATETPDISSSGGTITYHGVCLLLWSHADAERSTAIRRTLEASRSRKESNQSSLVTSRLKTLRSDALDQSDPTSLARKSARKSARGPWADAETDAETEAEGGISESEYEVASTVGHGPGESTLFLPGDTVFWLPYALTLVSRYPVYDLMRDYLTLSWARFSKDVQSHTLQISKILAHPAPRAGELIRLDASPGGESGSDNSLEVIARFPGGLDFGRGLVDINFTMFPLFKCLNIENILTICEIALAPTGRILFFSRHPAMLGIAVMSIKYLVELRGWNGVALPAVHSRDAKIYIDDPGPWIIGLATEARYSVRPSPEVCVCDLYVGFRNCMSPPPGCVSTKQQRERYRQRLQTAFDQHYHPDHSIPVEFKEAFPAGRFRPLCKIQAKRGASAAAVADQIKPPDWWHSTRIIQAFDSVLQEKYKKPSLLRRIGMFGAVKRPPQLTASEQMIQLSIRKRASAFVDARDDLETKIGRLSRRLNFLMTESDLWRDKFVTFEQYAEKLSSEANQLRAKINKEQRETKRLSGLVTMTAVEKNKLQNQLKETEGAHQEALNELAKMKDAMDTMELERADMIAEVEAQIERALASMAVGVDDSDYGSRPSSRLSNASSAPPSRRPSDAGKSRHLRSFGTESTLAESYEGGELRGPILAPTERANGTIQEDQEEDEDGTDTAEIKRKKRFSASEVDAPQDGMVAVDQGITEKSDKIAQKVFEIQAKVSLSLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTM5</accession>
    <name>A0ABQ8VTM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_606078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="63256" checksum="092752CB3C31BAD9" modified="2025-10-08" version="1">MMPDLPQELIDRFIDESSRSTEDLKNLSLVSKSWLPRTRYYIFRCITLAPRDPQEISEYYDYLDRKASAIRSGRSYHPLSFTERRLLHSPLFGNLQPQKVFMSSIRDTLHLVRGLRLQSFIRIGGERRISPEEYFHRWLGFGGHKSAEESILMRGLSIDDEFHERQKARWNAVDLPWGHRAGLHALSFRSLRFIHIQWSVFSWIPPFVALEGDDFPVHVDLDEWPGYQLAMLLKANENTLDQISIDEYPGFQLTTTQISDALLDLLMVNVPKLKSVCLGGLMQRMNTFPVPEALFDLSQPEDPEALLSLDRPRYPSGREVPHVYSNLASTRSNNSDGQSLSLDRLSVRGFDSESTLLIEDAFLNSGVLSAMKYLTLSSMPENFDYMFFLSRLCRTLTHLTLDLDKSTRHLDLQFHLLPNLTCLQFMIHSIVDEDILRNMILSLLNDGASELDQPITAARTVKLHLAFCHEHHPDHVKQYLIAASVDELLQMLILPTSFEPHQPMRTPRVDQITMDLPVNILSDSLPITFRTGSLNFGETDEWWYRPSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUB7</accession>
    <name>A0ABQ8VUB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_82302</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="425"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="463"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="425"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="463"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="155"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="495"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="661"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="404"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="495"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="696"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="745" mass="80120" checksum="DDBDCB7C726149BC" modified="2025-10-08" version="1">MTSHPDNVINRGNRWYFNPDADALANEIVRLNIGDAARDATDDAPIRTPPKNKLASAVLADTSPLETNSIPSTDSSPKAPDHQIVVSHSRGSSTDTTISSQDSATSSTSNAMLAHTPLKSGTISELKERPHSFSGGLSSADLRRLQQADEGFSDDNNQLQQQQQWSSGEQLSYPSLTPNNQTVHHRSQTQQAHQGPQNLNRDVTSPIDYNTQARNFNAPLQPGMAPSMSPTSPPYIQGRPNNVPVAYRQPPRGFPPQQGLPLPSPGYAHNGQISIGNSQQLYDMMLPGALPHDPAHPAVSRVQQQHNVFPRAHHHSASDPTAIRDPAAIAMLNSGMPPFPAGMFPTNLGAAPPQMQIYPPSFYGTQDAYRSDAVAAAQAMANRIQAQYTGQYAMVPSQLDGGMSSPSSSVGNQNGPSANNRKLGLYKTELCRSWEEKGSCRYGAKCQFAHGEEEVRKVSRHPKYKTEICRTFWVSGSCPYGKRCCFIHTELPNAGPTPPGQQPDSVSPPPRPDVRERSSSTNSDPNEAVSLLARISAKRTQDTGSNSSSTPVDNNVNNFQFGGAQKQRLKVDTSALDRNTMKGQNKSAYPTFASNGVLMAAPDNIYAKSPAPVTAGPDLGRHNNVRMEIVGYNQRMDKTPPSNIRHTTTGSEDISYQASQSMAGNPYNTLPSGDGAPSAPRVNGHVRAGSAGNWGNFASNRPNTQFSVSAYPHGPSPAGDGPSNSPWSTTDLAMGPSRLNEKAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUX4</accession>
    <name>A0ABQ8VUX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_964325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="278" mass="31052" checksum="AFD9D402175CED86" modified="2025-10-08" version="1">MLLKIYDAHPSPFQPLSDDKYNSKLQVIGGLSLGPNGQCAMAAFGPTALTYIRDRAFKYSAVKFVNQYGKVLGEFPFGSKERYGYGQLMATRAMVHEGFLVGEDREVDGNVNWSSNVLRVWEETDNEGCVCVEFVDGTVESSLTGFGGFIPLSSFTPFTRDASIKTPKPTIAMSWIGGFGFSLLAPLNSPDTQKKLIWFSHVEIKNPLPCDTPRFDMMPLLLDRHGSWKFIYVVCQGVMQNMVVEGLFLSVIRRMLCHLKVLEACHVQLKIALLLLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV06</accession>
    <name>A0ABQ8VV06_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_752533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF14">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11691" checksum="FA62C84C9357B436" modified="2025-10-08" version="1">MRTCSLWTRHRNVPGQILPKGSQALNLLQFATPFDLASTIILHSIQQDLALRRMIRAEPYMPNVYDEGSFFKPHRDTPRGPNMFGSLVIIFPTTHEGGELILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVC8</accession>
    <name>A0ABQ8VVC8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucosamine-6-phosphate isomerase</fullName>
            <ecNumber evidence="4">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_811107</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280:SF5">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="5">
        <location>
            <begin position="41"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="315" mass="34955" checksum="3E711007E6141677" modified="2025-10-08" version="1">MNQNGFAPGSFLPILYHRCSSALYFLVVMRLIIRETPPSVGDYIAHYICRRINDFAPTAEKPFVLGLPTGSSPIPTYKALIKLVKDGKLSFKHVVTFNMDEYVGLPKDHPESYHTFMFREFFSHVDIPPSQVHILNGNAIDLIAECNSYEEKIKKYGGIELFLGGIGEDGHIAFNEPGSSLASRTRIKTLAYDTILANARFFNNDISAVPHMALTVGVATVLDSREIVVVVTGQRKALALSKAIEGGVNHLWTLSALQLHPWALIVVDEDATAELRVKTVKYFKSIERVQDEVEATQRELKAKGNVPVPQVGSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVP7</accession>
    <name>A0ABQ8VVP7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_720226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="705" mass="79341" checksum="A15C1B3DEF27C06B" modified="2025-10-08" version="1" fragment="single">DEVQTTVQSRTSWSGGQAGAGAQGKKGRGQNGVMGKTLETPQISFLRFTPDMMRKIPIAIAHPDQCAMVLHQAKIDYFVNTTESNSKACLRLIRLRDRLSFLEDLKATDPIYVAYQEAEPRMHLVPSDFHSLGSGELSSITRLRRVAAEVDVLLRQIDSGLDFFNHTPQWVPRASYTFYEDLTESLLDNFIRTEGAWHRYESAATAQDARLRSVQEMKDSCRIQIINLNERVRRLGIDLEKAVNTIGDQDTLMRETKAALLEQIDVNKEAIRTCKITGGVEFEDLVEAATTIAFCPNPGMISVQAVGLSYKDNKRAGIESDDGDHIKPELLLEKVVSVRGGVEKLVQGYKLSKVESGTVDMDDPGATKLIMEKNEYMDIVGKFKKALGKANLKLVEDAFQAHIGVLFYAFCINATIKRNQSILDYNASVNILVKHKERVVALQERSSDLSDAVLAGTDPNLPGIAIMMQQLHAESLWALLEGLYMTQRALRFHSLAVDTELFPPTTSQNLSALDSATLGMVRTRLLRSYRNSIEETGRNPQQFVKICYYLTEADLKRWKRQVNMKTIIDIPPVYHETPIRDHSLAGRSNIRLDTVRFFVEGLKTTRPTVTLTLTQLGTEIIVDHRNKQNEFQHEQVRLQFQYQAGTMSLVESGTVDGNLSKNFNDPYAKIGPFASWMLEIDPRYNPGVNIKEATSAWFEFSGEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVS6</accession>
    <name>A0ABQ8VVS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NGG1p interacting factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF13">
        <property type="entry name" value="NIF3-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="30466" checksum="C288DAB91E7D737E" modified="2025-10-08" version="1">MSGAFLKAVSAAMERIAPLRLAESFDNVGLLLETPLKQSKRHRVMLTIDLTTAVVEESITKEASVIVAYHPTIFGALKSFTMANPLQASLLRCAAHGISVYCPHTALDCTWGGINDWLAEGIMGGNQAPGTVRPLQVEKFSPSGDSEGAVGRLVALQTPVTMGVLEERVKEHLKLSQIQVGYASTRDRLRSSAIVETIAICAGSGGSVFAGKKADVYFTGEMQHHEVLAAVAAGTNVILCGHTNTERGYLPILASKLEAQLHAAAFDEPFDIVVSNTDKHPLEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW61</accession>
    <name>A0ABQ8VW61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pinin/SDK/MemA protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17899" checksum="CFEDB5E14A2491B3" modified="2025-10-08" version="1">MPRIVPQIAWERRPTISKQREGGSGERIAIMESQMAQSLADLRASREADSKTHQYLRQLLRKQEDDHAQLIAMETRMAMMGMGGGSLAGPSRLTTERRRIVEESEEEEEGAEEEKGVEEKENGVEEDGEGEEMEAEGEGEAPAPTATKTVASEKGKGKEVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWV0</accession>
    <name>A0ABQ8VWV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="443" mass="51843" checksum="C3AB2F864C33AEDC" modified="2025-10-08" version="1">MIKQLHALPPVGLGLIPELEAPFMKDPASLKYGQKLPEFEKAKGPPSNAIFEIKEIEEGSKFTFPYKDGTRTVQLQRILFRSHGIIGRGTIVVRVVCACTHCVPNQCDWSGKKLVLKLSFPSVSRVPEQAFMDRCKEKAKGEHAWVLNHLPDIYCSFDIPCGERSPQANFKKKFEDKYEMRFLRGSIQDELQPLSTLETALECAQVFYDIVQCHHWVHTYPRILHRDISDGNIMVRVKDGKKYGVLNDWDLAMWLDEREGISTSQFRTGTRPYMAHEQHSPDWEGPHRYRHDMESLFYVILLLATLFSNPCEKDHEHSKKRQPYTKWFTQGDEFLYDKKALIIFDFLWQPIPNQFFSAFHQWLKSLQRCLYVGFTAYKYFVELQSDTPNQVLSFNDDTLDDHFSYDKFVLIMHRFSEEDLATHGSEWQGKLRGLQKDEDERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWX3</accession>
    <name>A0ABQ8VWX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carnitine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_809292</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF107">
        <property type="entry name" value="CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="675" mass="76270" checksum="E286964DA8AEBA54" modified="2025-10-08" version="1">MFKTLFNRAFFAQRLYRIYNIRMNHNTAAVLPRLPVPDLQKTVTKYLDSLRPFLLEDAAHGGPSYEDAFALRTKWADDFVYGIGRVCQERLHELDRASPDNWLDDNFWLKSYLQWRAPLLINSNWWLVFNDDPLHPSEEDLVSGFTEWQLQRAAWLVHRTLGFKDKVELQELHPVTTRTGVWIQESVSKMFNLARIPQRYCDILSQISSPSDPLSCNIIVMVNNWFYAVRVYDPGPDNSRILIPAETLLARLNVVVHDAATRAECAPEIGVLSADDRDSWASILQHLLSISPQNVKTHEAVVNSLMCLCLDRENHSIVLPSSSSSLPQPSSISQASLDSHLHAIRSVPSNVSNRFFDKPYSIIVDPSGRAGAMGEHSPADALVPSIVGEYAVVQHVEMTQSFASAEHSATNGSWSRLEWVVDDESLEAIRAARARAEANIKNSDDSLLWFEEYGSDWIKSVGFSADAYIQMAIQVAWYRTTGEFTATYETALTRMFNKGRTETIRTLSVESRAFVLAMTDNDNSISSETKWDLLRRAVQKHTSLTRDAATGRGIDRHLLGLRNMLRQGERSELFDDLLFARSQEWRLSTSGLSAGHHFRGTGFGTVYENGYGINYLAAPSMVKFGIETKFSGGNTSTEVFKDAVYCALREMREVILQVPHNKSTITHEQLIISRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXB0</accession>
    <name>A0ABQ8VXB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_811862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="340"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="340"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="435" mass="49339" checksum="995EE83913955A8B" modified="2025-10-08" version="1">MNSPHPPRMLDPQRHRHRHQPQKQQQKHQQHQSELDSLREQLAISKASNEAFLVELEALRSIHGQEHESLRSENAILRKEQDTWIKEKQTLQHELQKTTDDSVSALAAKDSLYDELRVQFEQQTHSFQQEKQSLEHQTHSLSAQTLSLQTQLQTLQSTLLSAQSDRDFFHTQYTTASAYTTTIRAENLALQQRAEIAEAQAAQGVAEVKEVYKERLRKAEEEGRVFSRIVDFMMKKDEATEGVRREAGEAPELRARCGELEGEVGRLEREREEREEERGRLEGEVGMLEDKITQLEREREEREGEWRREVGKIKQRIGIDVDMDGDVLIHYHDRDRDYIPGDPAAAATTTVPVDPVAGPSASPGSHPGSGPHPGSGPHPGPAPAPAPAFGAPSSSTPDPNQKVFRCEWREHDGPCLFICETRKELENHMIYGGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYX9</accession>
    <name>A0ABQ8VYX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_2037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8575" checksum="67571CB109448F6D" modified="2025-10-08" version="1">MALFLAVFGSTVRSKILLRVRSGSVLDYSREPEFTMSSEEPNRCLPSWMLAKSLYIYLTSAILRTNVCCHGARRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ44</accession>
    <name>A0ABQ8VZ44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_7757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045552470" evidence="1">
        <location>
            <begin position="19"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="143" mass="16696" checksum="CAFCFC831A684B61" modified="2025-10-08" version="1">MMFRIFQFLFTCISCGLAWQEYLSNRLRDHQWNSYDALTFIHTTFRVCPQAWMWGLRGDVIQEIWFLGRIAPKGIPGVQYPIEIEAYPVDDDFVPQTSSYSPRSMLCDLLEWAKNSLLCVGQQQDAEGRNVCRYTTPVRSSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZI7</accession>
    <name>A0ABQ8VZI7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_16198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="68"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="401" mass="44222" checksum="1022A0369E905CCD" modified="2025-10-08" version="1">MFTNIPPSVDEIVDKQLFIGNLSAAVSSELRKQLGITHILSVCPEFPSTGLNHLTIAVDDSEYEDLLIRLPEACQFIQNALTNGGKVLVHCVMGVSRSATVLSAYLMQSRKLNPTQALELIRTRRPCVQPNYGFLKQLDAFGQCGYHPSAEHPAYISWKRRQEQDVTVFLNQMIDTIPVIRQQLYLSSEFPEDVEQTQSLLFEFGITHLLSISPSTTIPSPTTLVQHHHISDSQQERDTILLALPEACNFIKQAIADGGVVLVCSEIESKAVLASYGYLMSSRGLTPKQVYQQLTEALPLFNRTSNFTRQLELFNACSFAPTSDHPLVKEWLNSAASSGWNSRRGSSNSSDVAAALSATALNVLSDTGIDCKAFGETLHKLQSTSRPSKSLARLQPIEVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZV5</accession>
    <name>A0ABQ8VZV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_808250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="54470" checksum="F75A8FC83C304388" modified="2025-10-08" version="1">MSDAKPTLLALFSSESISSLVLSSPVIRPADLASFSLASKRLRLTTTPFLYSRVILYSPNAIRKFLFTILHKPATYAAFVHTMYLSSYRGQPRLHLTMTREMNLALSNVLPLLRNLEYIYLSELWCFSAAIFASHGKIVSPLRDCRLNGITFSTQTRIVDFLRFLSSQKHLVSLRLGVVAVPNDHHDQQPLPWDEMISGDDHPLVLSDSLPALTQLDGPVFVATQVLRSNAPLEFLRVHTALEYDASFVREGNVLPVLFSSFIEVKTLCSEIVTSKMRKSLKSLVVLGFPGDDELQELHFSKKEPYRDAGNLLGDVIGDLMQTLALRCPSLLHVGGLPLSCKDRSEVHAALMEMHSLRSIEFSVTPWLGPSVMGISSLGQQHSSFPSPAIFKAISMEFKMYCPTLRYFVYTLRYPNPQSRYHRVERVIWVYHIVNRQQANGKPTGNEDGKGLEGEWTAGDSRSNWDELWKQVIVTITSVQVDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0D2</accession>
    <name>A0ABQ8W0D2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_892374</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF7">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="39"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="359" mass="37621" checksum="601F1A9DD56F8E28" modified="2025-10-08" version="1">MSLSKSFKAKIKKLLNNDRRVSTSSLPKTFKAAVIKSAGGDFEIIEKPLEAPKAGTILVKVLACGVCASDAMVKYGMAALPRVAGHEIIGDVVSVPAGETRWKVGDRVGSGWHGGHCHECGSCKEGDFITCSKEAINGVSQDGGYAEYVTLRTEAVLPISKDLDPAEAAPLLCAGITTFNALRHVPDLKKGDLVAVLGLGGLGHLGIQYAKQMGFKVVALSQSDAKKDLATKLGADIYLDGSKVNQVEELMKLGGAKVILATAPQGDAITTLLGGLKVGGTMLTVAIADLELSTVALIGKRATVKGWPSGHAKDSEEAVAFAKKHNIKPMVEKFSLAQANEAFGKMQSGQVKFRAVITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0Q7</accession>
    <name>A0ABQ8W0Q7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_749532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="167" mass="19603" checksum="35332CB02EA0A31B" modified="2025-10-08" version="1">MFQKLQSRCEICVIMLRECRNGDNQEGVKFFSFCLRAFEKMGSGGMSEDEDGVDKVHVEERELEEAVKLTMFLPFRHSTLTKLVVLVDEIPQNEGLKKLFVQSGRVRKRRVRGDPRCKTSDRKPPKRWYSSFFPDGYLNSLSEYQREKLRLSKKVFPLYDIETLPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0Z0</accession>
    <name>A0ABQ8W0Z0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_912944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052925">
        <property type="entry name" value="Phage_Integrase-like_Recomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605:SF4">
        <property type="entry name" value="DNA ADENINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="38851" checksum="5ADE81930B3076DF" modified="2025-10-08" version="1">MTVNILEDDAYIGIIQSINDYESMKPADILDDLEECHDNVGLELKDTGKVQPDDDPAVDMSTLLDSIKEVSKGVSEKTGQEYGRCDELNLNNTKKDASIERHSFTHAQKMRAAATFGFGRVHGLGMQAWHRSETTGKMLGNPSVSETLTSYMLSLRRRKTQIGETATSACAATSPQFREPQPFQSTARNTPKNSQDWAGARARSLLDLGYSLAFCGLLRVDELLKIQLHDIEFEEINGRWKLTLQLPFRKTSQFGAIKPFVWWIMPEEYSHLCVVRAFARWIVISDITNGYLFRKIHANDRIAEENEPMTSEQFLEMFRNNLIDIGVDHIPYGTHSFRHGGCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1E7</accession>
    <name>A0ABQ8W1E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SHQ1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_748406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SHQ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00298">
        <property type="entry name" value="ACD_sHsps_p23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039742">
        <property type="entry name" value="Shq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048696">
        <property type="entry name" value="SHQ1-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007009">
        <property type="entry name" value="Shq1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967:SF0">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04925">
        <property type="entry name" value="SHQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21413">
        <property type="entry name" value="SHQ1-like_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="52533" checksum="4DA79CE2C72AEBED" modified="2025-10-08" version="1">MITPRFSCSQTAESVIISIYCPSVRASEVEVNVDGNLFSLHINPYFLRLNFTHGLIEDDASSAQYDPSTGYLTVTLTKEIKGQEFRDLDLLAKLLAPRPTVHEPLIEVISSESTAEDPDNLVAQTQNLSLQEREIEEAAKNDWQLFQEVPPAEQPTLRVSAQYGFLDMYTGYFTNVTYTENEVNELGPEAEALTRLQRRQRRIKHEDEKWDEEYYMADFAEAEFIQELILWTHPHLSDNGTFTYTEKENATMLNLPRKEYILTRHQTYSLYLTLATVLFSYAYDARTTQHDPTSESAWTICSLISAFSALDPPPYHTESVNNSPMLEFSSDHISASFVPSYRRSLAFPLYRSFALAEKCREDVANLLLRGRRTVFRCLMETKDILDHHDVYYVYSKIWLDDLCVWTQACASDDALTRLGGLIKNASITKQSIGWELEQLEGVVEQLQAGGQRELDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A0A3</accession>
    <name>A0A9W9A0A3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dicarboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_521360</name>
        <name evidence="11" type="ORF">C8R41DRAFT_915502</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000029">
        <property type="protein sequence ID" value="KAJ4471321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A0A3"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="96"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="202"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4471321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="294" mass="31869" checksum="D752ED8860A2A81A" modified="2023-11-08" version="1">MTTVYPFWLGGVAASMAASCTHPLDLTKVRMQTIKAAAGTKPPSMFFVLRKSIVSQGFRSIYTGLTASLLRQMSYSLVRIGAYEEMKRRLSQKGKPSSIQLLAAACLAGGLGGIAGNPADILLVRMTSDVIKPQEHRFNYSNALSGLANLAQQEGFKGMARGLGTNVTRAMLMNASQVGSYDLFKSSLLNKTIPVLDYQLHDSLALHTLASLLAGTFATTVCSPADVLRTRVMTSTSKDSVLHILKTSLQKEGPKFLFKGWTPAFIRLGPNTVLLFVFFEQLKKGWNAIAIETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AC72</accession>
    <name>A0A9W9AC72_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetrapyrrole methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_514746</name>
        <name evidence="6" type="ORF">C8R41DRAFT_755966</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000017">
        <property type="protein sequence ID" value="KAJ4478690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AC72"/>
    <dbReference type="OrthoDB" id="4623364at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19916">
        <property type="entry name" value="OphMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038374">
        <property type="entry name" value="omphalotin_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4478690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="417" mass="46267" checksum="232B8A938337A58E" modified="2023-11-08" version="1">METPTLNKSGSLTIVGTGIESIGQMTLQTLSYIEAADKVFYCVIDPATEAFILTKNKDCVDLYQYYDNGKSRMDTYTQMSEVMLREVRKGLEVVGVFYGHPGVFVNPSLRALAIAKSEGYKARMLPGVSAEDCLYADLCIDPSNPGCLTYEASDFLIRERPTNIYSHFILFQVGCVGIADFNFTGFENSKFGILVDRLEKEYGADHPVVHYIAAMLPHEDPVTDQWTIGQLREPEFYKRVGGVSTFYIPPKERKEINVDIIRELKFLPEGKVPDTRTQIYPPNQWEPEVPTVPAYGSNEHAAIAQLDAHSAPEQYQPLATSKAMTDVMTKLALDPKALAEYKADHRAFAQSVPDLTANERTALEIGDSWAFRCAMKEMPVSLLDNAKQSMEEASEQGFPWIIVVGVVGVVGSVVSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AMJ2</accession>
    <name>A0A9W9AMJ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8J55DRAFT_558514</name>
        <name evidence="2" type="ORF">C8R41DRAFT_868983</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000010">
        <property type="protein sequence ID" value="KAJ4486550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AMJ2"/>
    <dbReference type="OrthoDB" id="2501127at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="21035" checksum="FB5DD7DB6AB8661A" modified="2023-11-08" version="1">MTDFPALRISFYFASALFSVVLLGLTAARIHYTTHIPLGDPLNSGKDFFDPIVAELLATSILAILWSWFIIHCIHRRYENRFISTFRGELIGLFILWVMYLVGAAIATTFWGKLGWCQMFLPCRVLTALVAFAWINFIIMTFILFIDIAFVVANGGFREPLHGRWDPRASHYGNSNFRTSMSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DQZ7</accession>
    <name>A0A9W9DQZ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_427693</name>
        <name evidence="10" type="ORF">C8R41DRAFT_770642</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DQZ7"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4481416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4482655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="190" mass="22161" checksum="2CA10BFBBDB021AE" modified="2023-11-08" version="1">MGKSQSKLSPEQLADLQKNTYFDKKELQQWYKGFRKDCPSGHLDKTEFSKIYKQFFPFGDPGEFADYVFNVFDENKNGTIDFKEFICALSVTSRGRLDEKLKWAFQLYDIDKDGTITYDEMLQIVQSIYKMTGEMVKLPSDEDTPEKRVDKIFRNMDRDKDAKLTFDEFVEGSKQDPTIVQALSLYDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWC8</accession>
    <name>A0ABQ8UWC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_906829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000153">
        <property type="protein sequence ID" value="KAJ4463783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="41676" checksum="4DC336BEFF427615" modified="2025-10-08" version="1">MSTFLSAFQPFLVIFLMSYLPLIFSLVAMAASTNTTFDDTNPSFTWQSGWIAAPCDYCSALLNQSLTYDGTWHDGGARTGLTGTFEFNGTAVYLFGVTSQNDTGTIEFTLDGNNATTYNPPVIAADDPTVGTPEADHTYNSLFFVATGLANGSHQLGFTAVLAYNTSQTVLIDYAVVTTDDSTSSGSSSASGSGTSASESASDPNKAALIGGIVGGVGGVALLSLAIFLFIRRRKLRVRSDRPENNIRPFQTVPSFITGESNSLITTSTLSSHPKARPPIPSISTPSPTETFGSSPINAHDDAVSTPSTRFRSNSGAATTTTTTESTIPRGRQEIQEMEQRIRSLESMVLLSHAVASPTMHHASTIMSPIMSPLSEQTHNASLDDLTNPPPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWK0</accession>
    <name>A0ABQ8UWK0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_872275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000149">
        <property type="protein sequence ID" value="KAJ4463949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48471">
        <property type="entry name" value="DDE TNP4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48471:SF1">
        <property type="entry name" value="DDE TNP4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="201" mass="22171" checksum="1B5D65D2C70CA243" modified="2025-10-08" version="1">MGFDVQTFRFILEGRGHFAELWNNTPIPRVDVSNFGAPRIGGRSLDAAGALGLVLHYIGSAILESQLQQIFAIVPSVLSRYLKFSLGILLTVLQKMEEAKITLPSSVEKYEELSSLITDRHSLLEGAFASIDGLSLPVQVSDDPEIENATYNGWKTDHRITNVLMFSPKDCRVGYAYHARFFRAPACSAGYQFKLGPSTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYE5</accession>
    <name>A0ABQ8UYE5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_985157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000121">
        <property type="protein sequence ID" value="KAJ4465863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="24844" checksum="B9ABBEA516C98BA2" modified="2025-10-08" version="1" fragment="single">MATSALPPGFYEIHIHNADNLEKEKILTPQSLGVYITSGTASTNATASPILHDWQISGDGLIVAFDKSNKSEYQTQTNNSPCQVGDYVTTGKVGGMRWIIYGAEWNLGDYWTAYIMSNDGTKLFWTINPSNSCVWLRQFDDICIQSIPKFHFVPVGPRDGRPLTQLPGWNRKFRGENPNHWTGTGILEAIMTLIIVNLYVIMQLCRGNHAGLLSVVYAEALMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYP1</accession>
    <name>A0ABQ8UYP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_872459</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000170">
        <property type="protein sequence ID" value="KAJ4463353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="172" mass="19068" checksum="F615A69D42633CDB" modified="2025-10-08" version="1">MFLRRLLLFDLYSDFWMGRANCPLFAEQVLLSAESLSLGLPIFLRDNLTQQWGVPRSTVLQLKVFTNSKIPCIPIPFCLHFREGSAMMRMVSSKDLDPFASLRGQSVLPGVPKTVSLPKVSDVISPSPASKAQAVPPRVLRRNREVESLKADASSFLLLPGPLVQKTPIMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZA2</accession>
    <name>A0ABQ8UZA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_738925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="111" mass="12964" checksum="EACD2085BFDF2B74" modified="2025-10-08" version="1" fragment="single">LRIRFPAIAQCYQDSVDYMKAKFGIHAMFGLFFNFCLNSPRKGIPRVFCRPHVDWKNTAFGVCMIFVFVGHFDHREKCWLVIWEAGIALELPPGVFLFYPSSLFLHFNVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZL2</accession>
    <name>A0ABQ8UZL2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="251" mass="27531" checksum="B716830BD10D4E63" modified="2025-10-08" version="1">MSTRKGQKSTADGGRSLVTSPPPSMVPTVQATPVAVQTRAAKRKSNILPVHSKENTTQPALKRMKNMPAVSKPGKSTSGRRRPAPVPTITTPAKNLARIQESNLTKTRGPITQPIEKRNKSRRGKAPIIHQSDSEVSADEQNLNVSHTRSAAEKEDQEDDDMDTGGGDEDIEVMDERQDDLDAGRQLQNEAPRFTITNTVNAGIRTTSKSKLHNPSLSFDDNSTLTKNLEFEFSPLARTTPVQFFPSFKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V090</accession>
    <name>A0ABQ8V090_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_70214</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4466561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="442" mass="48814" checksum="AB8E8667EF521679" modified="2025-10-08" version="1">MNEQQGLHVAIIGAGIGGLSCALALAKYGIQRIDVYEATSDLGFVGAGIQLAPNMGRILKRLGCWEPVTKEATEVKVASVRQHNDNKELGRVEFAHVREEYGTPHMVSHRFSLAGELYNACKEEKAITFHFDSSCSIKTWQPKPKLAVTPRNRESYDVFADVVLAADGIKSSVRPEILKEFGVDVEVTDSGQSAYRIMLTREQMESDSEILGLLEADQVTRWIGERRHIIAYPISNKNIYNISTAQPDTHFASAPSATYTTRGSKVDMLDSFKDFCPLIQRMLNLVPDGDVCEWKLRVHSPLPTWVRGSVALVGDACHPTLPHLAQGAAQAVEDAGVLAVILSMLPEARPDSINKALRAYERVRKERAETLVDLAAASCRTLHLGEGAAREERDKQFAALKTTGGPSPDKYLDAEVQKMIMGTDVMQLARVEFQRTFGMEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V093</accession>
    <name>A0ABQ8V093_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_45632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="61" mass="7502" checksum="B7D5D3548E17D255" modified="2025-10-08" version="1">MRISRMTWLSARVSGKSSIHISRVIWVECFYRSGSAWVFYRDNGLFGRTLWMWKLWKRNMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1I6</accession>
    <name>A0ABQ8V1I6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_854905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="58" mass="6888" checksum="A81F3FD963EE7614" modified="2025-10-08" version="1">MGSANTGEGSLNRGTGRRLREVFREMRQRRETEVKETELRETDKEEIYDRLEEFPGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1N0</accession>
    <name>A0ABQ8V1N0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_778246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="238"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="302" mass="34850" checksum="8A8454E694DC5C61" modified="2025-10-08" version="1" fragment="single">MVTWLRTYLDMSPDRATWAYVADALIAHHTPKTYENIDDFSKINIFLQLWTTDRKKLPKDLQDMISIAKKHGLQLEGLAFSRDIIRQMPIWLHGETKEIRRQHNLSTCKCLRNNHNVKTVGDTEKVMKLKHTTCHTNRRNCACLTCKKIRQDTKCEHPNRCYEKAQELLDLLPEKWNPLSRLPEDYEPKEIEPSRYKDGQTFDWRITTHGNLTDAFRIFTNGEKNIQLPDVERQLPNVSKTIEAYTDGSCIHNGTKDAVAGAGIYFPNGEYSNCAIKIPNHIKQTNQSGEILGIKEAVDITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V222</accession>
    <name>A0ABQ8V222_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13 14">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="3 13 14">4.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_924877</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:23732"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57557"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 14">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the diphosphomevalonate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="3 13 14"/>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029765">
        <property type="entry name" value="Mev_diP_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053859">
        <property type="entry name" value="MVD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01240">
        <property type="entry name" value="mevDPdecarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977:SF3">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22700">
        <property type="entry name" value="MVD-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 13 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8 14" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-1207">Sterol metabolism</keyword>
    <feature type="domain" description="Diphosphomevalonate decarboxylase-like N-terminal" evidence="16">
        <location>
            <begin position="10"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Mvd1 C-terminal" evidence="15">
        <location>
            <begin position="207"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR015950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4470268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="418" mass="45160" checksum="C1FA162E7E3EC5B0" modified="2025-10-08" version="1">MAVYQATTSAPVNIACIKYWGKRDTTLILPTNSSLSVTLSQDHLRSTTTSRADPAFTETKLWLNGKEEDIKSGGRLERCLKELKKMRKERIEDKEPNAPKLSEWNIHVASYNNFPTAAGLASSASGFAALTSSIAALYGLNTFPSSSAKPSIASPSELSLVARLGSGSACRSLFGGFVAWEAGSLPSGTDSLAVEVAPQSHWPTMHALICVVNDAKKGTSSTSGMQRTVETSALLQHRIKHVVPQRMEAIIKAIKEKDFDSFAKITMADSNQFHAVALDTAPPIFYMNDVSRSIISIIEELNRVSLEKTGHLLAAYTFDAGPNAVIYTEEKNVKQIIEIIVRYFPQAESNPFPDPFKLFGGKQPAAVPLPEGFNENVAKVWEVGSVKGLIHTSIGDGPRVLAEGETLLGVDGLPKTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2B2</accession>
    <name>A0ABQ8V2B2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_851909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4470507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="345" mass="39217" checksum="C0043B8F51669BC2" modified="2025-10-08" version="1">MSANMVPQKSQLNIVMGAMTFGKEGTNGARVHNVKDVEAILDEFLKHGHTEIDTARVYCAGTSEEILGQIDWKAKGLKLETKLVARHPDPNAAPSQTPVEEIYHTYEDLKKHLLRSMKALNTEQLEMWYLHSPDRLTPYEVTMKAVNDLYKEGYFKKFAISNYMAWEVAEIVGICKANGYIIPSAYQGIYNAVHRAAEPELFPCLRKFGISFYEFNPLGGGFFTGRYTSVDDQVEPGSRFDPNKAQGKNYRNRYWKEPYFDAVASIQTVADHHNLTMAEIALRWVSHHSLMKREYGDAILIGASSLEHIRQNLIDLEKGPLPEEVVTALDKAWESVKPYASKYHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2M7</accession>
    <name>A0ABQ8V2M7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="670" mass="73894" checksum="32E9A5F5FADDF270" modified="2025-10-08" version="1">MSNHPHTDTDNAHHGGHSTGHRYTDARDAPCEGEKENRPIQLQQLEAEVNQLRARNAELEHVAQMKNSSESHENVPERSIPRPSNLKNTSIAEIRQHMGLEGKDSDSKKNWLNHRKTVRDALTGAQLDYNLDLRSQDTMKIAKCIQVIDDCHPLFKRFKGSWASHFVLRQCWSNRVEWLDNRGARLDGEDSASIGQTSSSNDSSTPLPSNEQRESSLTPPPTPSHSQDSPPPRSSIHNAISPHSPRGSGYTSNDESICPEEEEENNITVQECCSTEGSSNPGCEKGCATAGTDGVHVQGRENYAFVNENQTEFKENHSLLDDSGWLHIGDNPSGPRQNLSTQFLKWTASKYVVVEEICTDTIDKQLPRKRSKVWMLESFCGYYLLLLATVDAREIPKDVPYKRDQAHPWILSLTGSDPPRSNLCWPKIKPLLFDLLTPTIAPTTILIIMHLSTISLLFLGLSSIAFAAPRPMESNLEGAIPGSSSQDAKALPVHVALAWDRPAGKKFPVPQDSRTQQNIQNGVRKFFGDKKVGKALGVTGKLEATLPVGECEYYAPKANSGQMALNSNMVQVSFGGLEICGGTCTATVVIGVRPGGDSRWRAIGNIGESVVEFQAQGSKPIGWINVDRATHMNSIGTTRVAPLVPAFEELRKPSQRSKLFCPDKHLFDPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3U5</accession>
    <name>A0ABQ8V3U5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_587020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="38572" checksum="D9713CD27EEC03EC" modified="2025-10-08" version="1">MDDTVPCVSFIGIVDFSQEARWLYMTPSVSDLLGYEPHELRGQPSIELVHPDEMARVRKLHYDTIRQDKAACLVYIRMKHKDPHKGYVLCGVSRTIVHNVTVGSVSFANSGSKALHNASTAQEITVISPTPELEFRRWHDPSPMPPMPIPESLRRSFDGLDGDSSPPPKSDEDSFTYEPLPSQSFRTAFILDRFSVHCTILYCSNNLLITANTIEKRSFFDFVAKQDEDTLRTWIDTVKGWGVNERGQPSDGGFGFGKFKLLVEGRDHIAGDNRPPEPTPARQRHSSNYLSHTRVRQSRSNGRGHGSAVLPSRTASSPEGEALIVDAIFSAHSDGLVVILRRGTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V401</accession>
    <name>A0ABQ8V401_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Septin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_898127</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="120"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="357"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="475"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4468063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="594" mass="65629" checksum="3D228594CC3C37FA" modified="2025-10-08" version="1">MFSLRRKSRPVPEPTKIRGSPSLPELNSQGIPWPESLVDVSSIRQDIPPISEHIPKGAAPISLQGAPHVIPFHKPFRPSGSGEGLPSISSLYMSNAPANSTNGPIPRTASSKYSQRRARAPPTFNLMVVGGLGTGKTSLLRLLLETADLSPTATVDQRAAVDRFLSGSSKPTQSIHTACVEICESRYDRVLFSVIDSPGLDFMEGRELKLERQVSSVIKYIDAQYADTLSEESKVVRKNKGDQHIHLCIYLIDPSSIMTVAERRIKSSLPTKTRSETTVSYRTPPDLIPDTCSDSEDEESPLTMAPAEIRVIRRLAARCNVLPTIAKSDSLTDDALKNAKEAVRRSLSEAGLDFGIFGPPQVSTPKKARAARFAGDLNDATDANNTEDEDEERHSRPVIKLRRPTVGRALSRSRSRRDLSQAAEDEHRPVSPDMESVASVRFSAHIVARPDLTTLMPFALIAPEITALNRRNTSTDDQMLNTAPSSPIQQSEDGHALSVESSHRHSYLQGPPPDALKNVFVRKFRWGTVDVLDPDHCDFSALRIAVLSTHLKMLKVHTKEVLYEKYRTEKLLARRATSQITDEQRDRLLQDLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4K6</accession>
    <name>A0ABQ8V4K6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="220" mass="24279" checksum="0618A12D8B2C5643" modified="2025-10-08" version="1">MSPSTYSYSLPSSNESFCNSSPSTSPEPSGSRRTSEPWTLLEDPVRVTPNERDVIDWMRAHPKESFVVDNDCRISALTERSAVLRNSSSFSRQKLLEDLEEEHERVDLTNEPAPAEERKHSIRRHNGIYPGAFSAVAGHQRIVHRRKGDRKHVQTRADPRDSRLRRGAVVAGSQVQSSQRSMSVAGASVLLGASNFVIRGGSIAPGAFSAIAGNQEIWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5I5</accession>
    <name>A0ABQ8V5I5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="53518" checksum="750B043277466C90" modified="2025-10-08" version="1">MGTTPVKTRSKPSAAGKNYRDDIIHRALTDASFPPSTPPIEVDKKAFSSPLCKSCKELIYEALSEDAPMDSVDSSDVEEQYHGPQDVAPYIDNNLGKNGVLNAEWIDPRFAASLYLCAVTIRPIADESITDDDYLLYHDMVSGITASQEKCIRQTVNFVRSANIFSGARFDPTPPCAITCPTINNKIHLILAEDRFFNAVFLTVGRVAESYIFCPKSFLVKDKAVRYIRGLHVHGLMQESQRLFACFGSLIGSSKFGCPVSEGIIDFHSNQRFDSNAWKDDPDNLSPLEPVTPGKKCDISNVLKNIHCKNPLPFSCAVPIFDGRDSFVASPAQLNQIGSRTYPLYKNSEEDIPTGCIVCVGYTAHTWQSSGSYKAPPLSLSLGLQFVVVLALPPGYDGPAPPKSVSLHPFPKPIYNTPTRTKDFPGPPRRKPSHSKPPSDNVAGSSHIPRDGNVDSDNDSPYLNGGGLKGGFEYHEDVMMLKSNRKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5R8</accession>
    <name>A0ABQ8V5R8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_846896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="80" mass="8865" checksum="D821C4CDAFB98217" modified="2025-10-08" version="1">MMPDSTTLLFSVFPVIYILSGPTGRHTTSLFSIFPGFCSQLGMQHDKPCHLGEPGLATCLFIKLLCWDLFECRAHDVFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6K1</accession>
    <name>A0ABQ8V6K1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_964809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="386"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="636" mass="70361" checksum="2DB68C18B9151A1C" modified="2025-10-08" version="1">MASRMSDRIRSKNTGSVVPKSLLPKSREQQAAQRKEKEDWKVAQQEAKKQKKENAKIRVAKQLDTQEGEDLSLLRPDLQPLILPLQQLQQKPKQGLTTLPDHGLGLGPGGPSVTDSPANLKPPTTDCDNMTTTTVKEGYRDHSDDSEDDEELKHLEQELVKKRQEKKAQKTALRRAITAARVESPNESITPIKRPAVGILEGETESKKRSKLSEIGGLVPAWKSILSTQGKISTAQPPLDVEPIDLGEFGQDDTADTLKIQRAGKSHQKEQKIAAKDIVEVKLESVDADLIANEERVTGKPAQPPKSSRRMKTADVPFVNAGDQDVWNTRILPALIEWSGTRQSQFNINADPELRSKVRDLWNIHLATIPPHCLDQKGNTILRCDHPAILSYAQNKLRTYRSHIGRNAMRIVSDYVANNASTVPERQEIVQKLLRNNAFIYEKVGATRDLSSGAWRGELLMQAFAFYITWALSAPKNDLDSISDEPHFPVGALALTAAAVKWALTLWEPGYKITQTSTEEDQLEESGDSPEAKTKTKRKHSGTPKAPRNHTHSFGERWSSDCNKFQESTTVLAEPKWNLIFAAAEVHLLGVPNAGAGPGLKELRRDAQRAVAGMSVTSTGNSAKIEEEPDAIVLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7E1</accession>
    <name>A0ABQ8V7E1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_844091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="473"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4478526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="57984" checksum="2D1E99E16ED5E4BD" modified="2025-10-08" version="1">MQYGHLGMGERRDSGMDNGSTTFQSHVPSLNQALVHSHGHIGSAFSRAHTQDYRVSPSPPIHPQQNGQPAQQPKESYLAYGVPSASQVKRKHITDGVLNQTNNKRRRDVEDADSFDDPGGQGAKHWTDEEKSKLFKWLMGPGQDDHWNSLRATKNSCLRECAHEVFGSKKTYQALKGCYERNFNLFKQIHIFENFLGATGSLELSPDLSETDSLREYERRLASARKAGCDVGNITARTIDQWHRNGWYGLFYSRWNGDPATTRSTNSRLIHGQSNGGSGVPHDDDDNDDHGLDFSQPLTQAVNSVSGLSHDRSSSLAMSFMNPSEMQHAPPISPHTNVHMSTQPVHTSPILSSSAPPSGSLVNNLLGSSNSLSNSSSLLNSSLNPALLQTGSPSFSSTSTLSSTNTASSTLISSSSSSASNPSSSTPSSALTSSSDQAVVNVTITQSMVSSYLQFLQVQTQTSKMKLEYMRKREEREERDSQQRRELERLKMERERAEFDHKQSSANTKQKADRAIVGYFFLFFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Q2</accession>
    <name>A0ABQ8V7Q2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_772285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="25649" checksum="EC8720134B0C51EE" modified="2025-10-08" version="1">MIDVDEDGVDENEIPCTCDGFAYEWLLDAIEEELVSVTGAPPLYNSDPHRGGHGAVVHPGVPRDDRPHGTEEWKLLTDTLQHSSSSVSVFKNTNPPPHSSDQEQFPPSSVEAQYNDPFSSWILQLFDSDVRSRSQTLDFCVQEFKRICGNMPQEEWENAIKKEITEELGRMQISRGFREELRRFVVVTGSEDKDIQTDQGGFEWVAPGSFKFHDVTDDNDLDAFIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V879</accession>
    <name>A0ABQ8V879_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_771808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="75" mass="8427" checksum="F0CB7A86BE9680D5" modified="2025-10-08" version="1">MAIVFRTRSEEIALGMTLLGLFFSSVLYGLALSQLYTYYKRFPRDPLSVKVLVCAIPSPVILDTVSVLLECHACW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8I6</accession>
    <name>A0ABQ8V8I6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF261">
        <property type="entry name" value="ZINC FINGER CONTAINING PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="159"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="512" mass="55784" checksum="2B044581EBF7A2A5" modified="2025-10-08" version="1">MHDQTSSPNSSVAFGPLSSNSASSSSLSSSSSGDDLSPLFPLSYSPRIPTMAKKRSHQDLPQLSIPFKPQTRIASFLHLAHRERSPGKDAWTLESPSAVLNSQAGPETPSSASTSTPISPVTSIPTSISTPSSTSTPETPNSLSSPIVGVVDLTRNLKTISSGPVSHGGYSDIYQGELEITKSDQNEAEKIPVSVFLSLHYHLRVIITPLFTTLLIYSLVQVAIKLLRVLSSKGYDEVKARKRLNREVYVWHRLDHPNIATFLGTSYHIANRPSLILPWFKNGSASEYLRLKNPGADRLRLILDVAEGLEYLHTCKPAPIVHGDLKGNNILITDSGHATLSDFGLSQVIEDLVCPTGITPSKFEAGPIRWQSPEFLMDVSETCRPQLPGDVWSFGCTAYELLTGNVPYHFRRRDSTVIHDIQADIPPPGVEENNLHRGDGGIWDLMNDCWISSPVKRIHMTEVVFRLRNLCSRSSCGSSSLSATSASRASSCTTATSASTDVFIAPADKRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8J5</accession>
    <name>A0ABQ8V8J5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="313" mass="35161" checksum="E6E0083A245923F6" modified="2025-10-08" version="1">MIQYFETGASVTVATFGVESTDEIALTPSTILPPPSQNPHLRSNCSDCWASEPLIFSWKVKGSVKEKTFPTPTSIVDNAVTSVGAHTTSPTLSQLEICRRYKCPPNLMTGAREPKQSQAGYILGGRPECSGWTLKSENEEEKKHIRNLELPYTVANLVNRLDLSICAPTPRRKSIVTRYMHMPQKAIIWRFVGMHRECKISHVNCINTYLCFAFTILDSIWHWQERQMKEPEMCILSTILDEVQHPQYMSNNLSIRAWWLVLLPVSGFMAAMQSCLDNPLPTNGIDILATLLQVLFEGIGANYRIDVAGPGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8T9</accession>
    <name>A0ABQ8V8T9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_905137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045161570" description="Protein kinase domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29368" checksum="95E8E8A05A7FB740" modified="2025-10-08" version="1">MLQMRLALQFVLLIAPLWFKTATQAAPPPLSPQQFRKFLLGDRDRPWIEDFYGSDKYLNDEDKNAFKQRLIGVTLGEKLSSPGAVTGSFNEGMYMLGADYNAKDKKYEASEVVVKILYGPVDGKILGEVKALKDVGYFIASGLLPSNGKPAMLMKKIDGAQIKSTGVWKKANQSGREELLNQMKLLVKNEIVTWADEKRLLHADFTSYNIHVTFDKDDSIKTCRVLDFGFPGIFRVGTSATKSDIEEWFELQWNNRKQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V916</accession>
    <name>A0ABQ8V916_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxidase</fullName>
            <ecNumber evidence="7">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_770970</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF53">
        <property type="entry name" value="HEME PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 7 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="55"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4481306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="515" mass="55468" checksum="5984A01C395B4684" modified="2025-10-08" version="1">MLQYPSISYAIITFGLAGWVHSLSTFQWPNPQLAYTDKLIYESGLNLLAQGCPSRDNTTVPAQWLRIAYHDMSTHDVDDGTGGLDASIQFELDRPQNIGQGMFDSLNDFRNFLFAAPFFGMADTIALGAVLAVAGCGGPLIPFSAGRVDATEAGPATVPEPQQDLASHTEAFRRQGFTPTEMIGLVACGHTLGGVRQVDFPLVVTDTEVDVQTFDTTTNFDNVVVSEYLQNTTQNILVVGPNVTTRSDFRIFSSDGNVTMQSFLSSDTFNETCGNLIERMINTVPGGVTLAQPISEPFDYVIINPSDNPSRTVTMLWADRQGSSCPSSGCTSPSTGSLQASLGIFGGIQGLTADRNTFNATINATTSISKFWFEINENDGSDPVVVDNGGSGFVIEQDSVFIDNSRSKFVFLTVSEISYQRLVVAVRGDASSSVSITTFDPHSDASTPPYLPTIMTTNLQLDDSNPVEGGYTFFTANVTGTVTFLNISGNVGDVSYAQENFDMTVVDFPFAQISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9U1</accession>
    <name>A0ABQ8V9U1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_840869</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4482621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="470" mass="52956" checksum="03A0BDD8C2F75254" modified="2025-10-08" version="1">MTVRNFLWGQAPSTKQERNLLFKLDFFILSYTCLVYFTNYLDRSNINNAYVSGMKEDLSMEGTDFNKILTIFTCGYIVGMIPNNLMLQILPPRLWLPLCQIVWGVLTFCTSAVTNVQQVYAIRFFQGIAESSTFVGTHYILGSWYKPGELGKRSGIFTSSGLAGTLFSGVLQGAVYSNLNGVSGRSGWRWLFIIDGVITLPIALYGFWLFPDVPATTKVFYLSDEDRQLAASRLQGYVEVRHSPLSWKLAKKVLTRWRWYACSLLFAISGETESFGSNNLMGQWLKAIGGYSVEQTDYYPSGVTAFGILSTLVCAIWTDYTQVRWPVLVYMSVSCIVASICILVWNSPTGLKFFAYYLAGASYSGQATTFAWANQICADDDQERAIVLASMNMWNNVVNAWWSIVFYPATDAPKFTKGMIAMIVICVATLAVTGLVWYLERREHRLGNRLEDTPTRDSEQEENQSTKENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA69</accession>
    <name>A0ABQ8VA69_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_773803</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18 19">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11319">
        <property type="entry name" value="AmyAc_euk_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013777">
        <property type="entry name" value="A-amylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015340">
        <property type="entry name" value="A_amylase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF215">
        <property type="entry name" value="ALPHA-AMYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09260">
        <property type="entry name" value="A_amylase_dom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001024">
        <property type="entry name" value="Alph-amyl_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632057" description="alpha-amylase" evidence="14">
        <location>
            <begin position="27"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="15">
        <location>
            <begin position="36"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4476250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="562" mass="60534" checksum="0F48C4662A0C18C2" modified="2025-10-08" version="1">MKNSWRAVAVAVSTVLFSVTVIAASAEDWTKRSIYQVVTDRFALGNGSSPRCATNERKYCGGNWQGIISKLDYIQGMGFDAIWISPVVENIEGTTIGGEAYHGYWAQNINSLNANFGSDEDLKNLSSALHERGMYLMVDVVVNHLVAVPTNTSSVWPETFDYSLLQPFGGSHSFHPQCFISDYSNQTDVEQCWLGDASIPLLDIDTENSTVVDTMYSWVKNLVSNYDIDGLRVDTVKHVRQDFWPDFASNAGVYTVGEVFTGNVSYVASYTEGLDSVLDYPTYFAVYDAFNNPTFGNMTVIADVVTQAQDQYNHGTFYVGSFVENQDNPRIQSTVSDQSVVKNFITWPFINDGIPILYYGQEQGYQGANDPANREALWLSGFSTEDKPLLTHVQALNSARKQAISYNSSFLTTKASFISQSSISTLAISKPPLLTLLTNGGNSSNATWIIPSTAGLYSPNETLVDVLTCDSVMMASDGSLNVVATNGLPKVLMPTEALNSSGSFCGSGSQGSSVSVGPNGSSASAGSNGSSSPGGLKGLNGEIVVVIMSLVFTGIVSGMLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAB8</accession>
    <name>A0ABQ8VAB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_868700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="238"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4484071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="546" mass="61562" checksum="D9287FF0BB2839D2" modified="2025-10-08" version="1">MSEAAEPTNQPPTEQPEAEGQNGPSKSELKKRAKAAEKEKKAAEKAAKQQEMAAQKSAAEVDYAAEFYGTLPLHQSQSRPHRPRVDIASLPSRDGETVLLRARIHNSRAQGSKMVFLNLRQRIESVQALMIVAPEKVSKQMLKWAAGLATESIVLVEGVVKKSPEIIKSATVGTVEVEVSKLFLISGVEARLPFTVEDADRTEAEIEASGDQFNRVLLDTRLNNRVIDLRSQTNQAIFKLQAALGDLFRQFLHSNGFIEIHSPKLQGAATESGASVFKVSYFKGGAFLAQSPQLAKQMAIAADFERVYEIGPVFRAEDSNTHRHLTEFMGLDLEMTIEEHYHEVMEMLDGLFISIFHGLREKYKKEIDVVNKQFPAEEFKWREGPDGTLKFSFREAVNLLVEDGVAREDLDDINTENEKRLGRIVRAKYETDYYIIDKFPMELRPFYTMPDPNDPTLSNSYDFFMRGEEILSGAQRIHDPKLLEQQMRNKGIDPESMKGYLDGFRFGCSPHGGGGIGLERVLMLFLKLNNIRRASLFPRDPKRLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB62</accession>
    <name>A0ABQ8VB62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_868384</name>
        <name evidence="3" type="ORF">C8R41DRAFT_872230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000146">
        <property type="protein sequence ID" value="KAJ4464157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4485103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="41025" checksum="8E86F6D132B98CE2" modified="2025-10-08" version="1">MSLSFERMVYTRSLLPMSSSHDQNLTENLQVLLPDHDGWYRSMDANQLRTDSSSEARPVYRENETRNNSSNEMMDGHYGVEESDDDRATQSLRIISSNSTTHSGPTNIFQRSEDPAVENLISHEPISPGVFELRSNSDQKLDEFVPIAYMGNAKLSKDESGDDMAMDIAETQRHFDTTSTSPVLDIPVLPSSDEICNQGENQRKIEEDKLDNSTTSLPLSDAPVMLASKEVCNPTENDSHHSGQEEDESGPGLILYHVLRDLILLDLDLPKILFTAGCIGYLLFLVRAFWKIRIMFRDQPLACFGHVALSVGLLVFIRYNGRQVQGRYQRSGLLPFVVDTIIFIGAFIFCVMGDIANVALSVIIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBD0</accession>
    <name>A0ABQ8VBD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_839268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="398"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4484647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="45289" checksum="D9DAB33446030F96" modified="2025-10-08" version="1">MASGAPASSATTSSSSPTSASTTTSSSSSTTSSTTSSNTSNTSNTSSSTSASNTASSAQSSGSSSGSGSSSGTSSATKTSSSTTSTSTLTASLTTAVPTTVVGTSADGQVYTTVIQTSTVLPPGATVTSSSSSDSGSSSSSDSHTGAIVGGAVGGGAALIIVLVLVGMWWKRYKQKQRSLEAFDGNFDPDRIVTEGKAMKGEPKGMRGRGATLPNVGDDDDGMGGRLAGSALGAGVVAPYPLYHPTNANAIPPEMSTQQQNSNPSSTSLGYSRPSTHTRSPSLGLSNSGVPASVYAAAYGENGPPPTQPQGSNAPYGFGVGERLPNPYTQNPNQPNPASNTGSTSTHTTHTGAGQGYGRFNVANPDPGAGAGASSSSAAGPEGLFVGGFTPGARVENKSAAGPAFGGRSRDVLVHQDGGRVDVPRGEGEGEGPDEIPPTYDSLLPDRSGSGPPQRGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBY6</accession>
    <name>A0ABQ8VBY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_770995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013898">
        <property type="entry name" value="Atg43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38699">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38699:SF1">
        <property type="entry name" value="MITOPHAGY RECEPTOR ATG43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08589">
        <property type="entry name" value="ATG43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4481311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19530" checksum="4BCEC9F63B3934E3" modified="2025-10-08" version="1">MSSKAPLPRHRNLHEYSDRQSSAAHSRPHFPPLPDLRFEVTYLQSIQPYIRFHQRPANARPANAKTKIPDFAKIDQTTSMKTESLKLLEGEEVIEIEWMGVLWITVRDQIISPLIQGTLWALVSFYVSPFSARVGHGLVERLPSRPASTKKGRGAELFRDWVKGLGLSSSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD16</accession>
    <name>A0ABQ8VD16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_840242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45924">
        <property type="entry name" value="FI17866P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45924:SF2">
        <property type="entry name" value="FI17866P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="72"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="914" mass="98950" checksum="9F428AE68DB81F22" modified="2025-10-08" version="1">MSSVVRNKLSPSLPDDFDQSLTPPRTPSKSSDSLTLRPTHPGSLPNFEPSSVPVTPTTPLSPNTPSEGAKPKKTNPLNDLIDTERAYVDQLTAIIRKVAAAWSRSNLPPSELDTMFRSIETVYKANRSLLTKLKEIGTNPSSPKALGDLLMRWIDDLETPYSTYCSKFLSGFDMWDPVQSNPKLGSILANMSSSNALSTGNEVWTLDTLFILPKARLKYYKKLYGRLLKSTAPGRSDYKLLVGAVDKLERLLDTLEQRESIRVGYPDDSPAPQYAAHELEDEVVLDMRTESSPPVLPHRISEVEVTPGSGSDSTRDSGISAGDRMSRETVSTTTSHSSTATLSMPIADLERRLSTARCMDIFTMTHKAVKLQMSPPSLTYTREMRCSLDLVIRVTPRVTGQEIVHRRGHIFLLSDLFLVCERMSLEERATSGSNGPDMWLCYPPLTGKVLRASEVPGSDTEMQVHIMRKETLTLCLETRQERDAAMKDFGECIEFASSVGPVSKQAPPPVPPLPAMGGLPRSPVPIASPSGNSQASSPSISRTSSPPSQPSPGMESIASRTSSFNTQSPRSSESGSISDQFSRMGMSNMASPPSAPKRLPSFHDQRPTSANSSSVGIGQVFPVSRNPSLGSQHQAYPPYGSGPGRGAPGPPPPPMKGPMQHPYPGGPARNMTAPSMQGGPPFDHPQPRAPFMDGLPPRPPSEPPMQANPPGRRSPSTRSLSAQQDHPRYNNMSPNGYPSNNTNVNNTMTRQQSSGTPLHAPQPRPLMPSATFNRALAETSFADPSPPNSPVAESSSLPTGPVTSSITATFKCKVFLKQQHAQWKSLGTAKLNLYKESPTNVKQLVVAADDKNKTVLISTIVLTDGVERVGKTGVAVELSDRGARTGIVYMIQLRNEKSAGGLFDSLLDGSDRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD48</accession>
    <name>A0ABQ8VD48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeodomain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_396513</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="58"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="58"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="109"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="117"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="19562" checksum="48E70719F3939286" modified="2025-10-08" version="1">MALRERRPWSPEEDDLLRVAVLKEEPGNPNPSKWFAISTHVPGRTNKDCRKRWFARMAADIVRGVWSADEDTKLLSAVEKYGTKWSLVATMVHTRNSDQCAKRWTDTLDPTIDRSGWTLEQDRTLLDAVNEHGTCWKKIVKTYFPGKTGLSAKNRFVLYSRFCDSETIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD59</accession>
    <name>A0ABQ8VD59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional adapter 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_836747</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016827">
        <property type="entry name" value="Ada2/TADA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025024">
        <property type="entry name" value="Transcriptional_adaptor_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="11">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="89"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="14">
        <location>
            <begin position="94"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="94"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="12">
        <location>
            <begin position="481"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="271"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="441"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="570"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="459"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="574"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="590"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4487439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="619" mass="69166" checksum="2EA229EB20323577" modified="2025-10-08" version="1">MTVTQRKVQTNHDQTNHDDIALHEPGGEYHCDSCSSDLTHAIRIKCADPVCESGDGVDLCPTCFCAGKEFAGHKRGHPYRVIEISSQPIFSEDWGADEELLLVKGIATHGFGNWKKIAETVRTHTKEECAAHYNEVYINSKSWPLPPMDRTFDIDPADFQDRKRRRITEMNAAPLPPLKPTPVSLPGIHEITGFFPGRLEFEHEIDHEAEDLVKDLEFGVVMQHGGDQIPEDENDLDVKARLRWEDERRNGGTSGKKGVFAGKSAGKGLSNGIVNGYHSSPPLVPKEVTAPSNSGNEEGNEEDVEELTQPPPIETEDSLAFKFTLMEMYFQRIEKRLESKSIIYDRGLLEYKKIQASEKKRPREEREIIHRFRPFARLGTAADYEAFTADILYEALLRKRIKELQDQRRLGLQTAGDVEKFEIDCTRRPQIKANNREAFAKSLRQSSVPDQRRASLTLHGDDGRKSHDREATPLVPNTSAPVVRRPPPPLNLANSPSLHLLTQGEQALCSQLRILPKPYLVIKETLVREYARRGGKLRRREARDLVKVDVNKTSRVWDFLVQAGFLKITPDVDPSTSTPSTSANLSTSAGATNGSPVKEVSSTPMATGPPSAAIAHPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDA7</accession>
    <name>A0ABQ8VDA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoglucanase</fullName>
            <ecNumber evidence="9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_840870</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the glycosyl hydrolase 9 (cellulase E) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033126">
        <property type="entry name" value="Glyco_hydro_9_Asp/Glu_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22298">
        <property type="entry name" value="ENDO-1,4-BETA-GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00698">
        <property type="entry name" value="GH9_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044988860" description="Endoglucanase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 9" evidence="11">
        <location>
            <begin position="53"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4482622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="618" mass="65963" checksum="E1DDF1D6F54F51FB" modified="2025-10-08" version="1">MLLPSCLLALTFASIQVYAQLSLPSPPWLPANASAGAVATTGSNTSVPNEQWSTLLGDLLYFYEAQRSGKLPSNNRVSWRNDSATSDGSDVGLDLTGGYYDAGDYIKVSFPLSFTLNSICWGGIDFGMGYDLSNQTSYLDSMLRWGLDWLIKMHANTSTLYVEVADTGIDNAYWGGDQNIPGPRPSFQINDTSPGTDAAAGVSAAFASCSYLYYGGTLSPTTIGKSSVNSTAPASLKNTTYADTLLIHAVELYELAVNASGGMTLYQNSVPEVQDSYASSGYGDELVMAGLWLSLAVNASQNANSTLNITTLSPQQYYSLAESYYSQFDLAGQNSVFNWDDKTAGTYILFAQMSSLGFEGAGNFSQWQTEAERYLDVVVDPSSSKGDASLTKGGLLYYSGDSDDASLNPALNAAMLLTRYAASGLCSTNDKKATYLSFAQSQLDYTLGNNPMFVPYIVGLHPNSPINPHSAMSSGGDDIGQIDTSPPLSQGNTYVLYGAVVGGPDRFDRFFDIRSDWVENEVALDYNAPMLTLTAMHIVTDDTDPYFTQVTVGANEKVKPKGQPCDDAIQDGCSGHRLSEGGEIALGVVLGVVGLVVVGLLAVWLWKLRSTGSFGGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDF1</accession>
    <name>A0ABQ8VDF1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="397" mass="43709" checksum="D566A7972274B723" modified="2025-10-08" version="1">MSEPTPSTMDSNLPGNINTSKKCGGQKTKHVKDIQSTATEPAKTVNKRKPATQGGPGTKMKKTKKATTTNSAGQKSVCVPLQDVTNELGNVSAPAPTNETRQNPNDNAHALTPVANVGNGPALTPNIRTLVETNTLTPTDLEAAKAQFFKEAEERFKDLERAQKVNQPLAATAANMARTPERVVEDCQVPAAPKRQWPPIRARKHDRGVFQNQYRNISAEKPAVPLLTAQNLEGQVEQVTGTVETIERPQGEAGDGKRGFCLQDAVDLEQNGNEYADFLASVHTNATMARIDLNKTYRQQDPNVISLVCRKTAIDLPYFGKEHFPGYWATREALKQYIKNQRKYAECQRKARVSGKHFLKDKRFRSGNDVYISDGEVSVEDNHGEGPSGTHHDEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE24</accession>
    <name>A0ABQ8VE24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 79 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_896196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045592927" evidence="1">
        <location>
            <begin position="22"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="2">
        <location>
            <begin position="431"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4487434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="532" mass="57642" checksum="8D1A2D5885EE4CBA" modified="2025-10-08" version="1">MSPSRIPILFLAAAVTELSHAATLISTDSSFTDINVVLPPADNAVTISPSFVSLSIEQDRWTDWSGTTSSNQFFYNVMENLKNLTGSPPGIRIGANSEDHTNFDHGVQYAEDIFPAPNPTTPYPEATNITVGDSYYTTAKYLLPDTEVIWGVNFGQNNLTAAIVEATSIMQAFSGPEISNLGISLKFLEIGNEPDLYMNNGLRPKNYNVTQYVSEWTHFADAIFEEIKLNTTSTRFLAGAFAGSSSNFEGFSPQAIFNLGISNSLAGQYIQAFSEHHYQGTFCSGSEGVLSDLMSKANIRGNLSQYASDIQATNDQGFDYILGETNSYSCHGAPGVSNTAGAAIWALDYALYSATLGIKQVYFHDGIGFKYNLIQPLTLTRSILDGSPLSAPLPPHIQPQYYAGIVAAEAIGRYGNTLISELPIDNPQISGYSFYDDSQVKRLVLINHTPYFQADATAVKIYFPDRCGTHNIVAKMLEIQHSDDTSGLTWGGQSYETPDGLIGGFVSARTVALNEHLGIPASQAALVAFQCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEG3</accession>
    <name>A0ABQ8VEG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_981403</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4491675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="634" mass="72520" checksum="010B5C8051A36E06" modified="2025-10-08" version="1">MIPPGPALIFRLVLPQILFVFCVYAIKIAIENQGHTFSTSTRWLLYISAFFARPLWMLFLARPYMNILNARRAAAKGAVLPPLVKESSSEVLASVMRSFGNGYIGKLFVYHLPVPISTVDPIRFKGEAYLEWAQKYGNTYMYQAYTETRVMTLEPEHIKAILATQFNNFEKGLVNYQQLKSLLGSGVFNSDGDMWKTRFHRNMTRPFFSKNRISDFDIFERHADDTISAMKQRLAQGYPIEFQDAVGRFTLDSATEFLFGKDVGSLGAGLPYPRGTPIIQKDSSTFNHPSNVFVRAFTQGQDQAALRGRRGDMWPLAEFWSDKVKAQRAHVDNFTNPILQERRYEQLARGTTSRSKESDEDGEGETFLDHLIRSTDDDQIIRDEIVNILVAGRDTTASLLTFAIYVLTERPELTERLRKEILEFVGSNARPTYKNIADMKYLRAFLNGLTFSGWKSDILMKFNPETLRLYPAVPFNSRYSKTSIVLPAKNGQPPLYIPAGVKCVYSVFLMHRRADLWGPDSLEFDPDRFIDDRAQRYLIPNPFIFAAFNAGPRICIGQQFAYNEASYFLIRFLQSFTGFKVDWAVQPESSRPPAEWEPLPGTTKGREKVKLSSHLTMVVKDGLWVKMQEREIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEL4</accession>
    <name>A0ABQ8VEL4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_920310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="93" mass="10174" checksum="2AB16ABEC735FC41" modified="2025-10-08" version="1">MGTKCILTALSGSSLYCGHTWDSFIANTNWNDSSNNVPYASRQSTASWFYIVPFTLDKNDYGSTIQTANSIMRFKTPGTMGFAAVDGAVTRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEM8</accession>
    <name>A0ABQ8VEM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MIF4G like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_920355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027159">
        <property type="entry name" value="CBP80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015172">
        <property type="entry name" value="MIF4G-like_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015174">
        <property type="entry name" value="MIF4G-like_typ-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412">
        <property type="entry name" value="CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412:SF2">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09088">
        <property type="entry name" value="MIF4G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09090">
        <property type="entry name" value="MIF4G_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G-like type 1" evidence="2">
        <location>
            <begin position="325"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G-like type 2" evidence="3">
        <location>
            <begin position="534"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4491734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="906" mass="101735" checksum="A5924E9D950C38CE" modified="2025-10-08" version="1">MSYNRHYRGGRRHYRDDEDERRRDVVESPQERMKNTIIRLGEVDPLQEISAVETSIRELAPPDICNLSESFHIGVTEQPYKIPFYAALLRLLHNNPSKGGDSIGADEISLGKQILEEFWKGFQAYVDKLMWRETRLCIHFFAHLTSAQLISTESFAALLQSFTAVLDEFGVSHGRAKRAALCAAEGLMIAGAVLTLATPTFSREIISSIQVYTETTTSGKWIVQPIVRLHSPAVTVENADEILDTALVVLKALESTDFVGPYPRPYSEYPPLDTSTFSEFVLPSVLVPPEVIELDGLSTEAEESEIKGEEWPEYFLRLFGDDVTPDPNTPAGYAVRTDLLAIIDIFEVNRKEAARLLLEYPKWVVSGTFKPKPGAPPLEVEPLVTYDWQLESTLLETMLGASLVLPQSSQSQIYYDSLITEVCKLSPSTVGPSVGKSIRKLYSSLTDGLDVEIARRFSEWFAIHMSNFNFQWVWKEWIPDLELAVQHPKRAFMRTAAEYEIRLSYYDRVVKSLPEAMHAPEAHVLPKQAPGPDFLYDDSSKPHHDAAQSILNLFRGRAKAEDVIAHLDTLRNTLESEISETENVNSLVRIISTQSLLHIGSRSFSHLLNAIERYLPLLRTLASGGVTASAGAGNPEAKADILSAAASFWKYNPQMVAIVFDKLMQYQIVDPTDVVSWTFLHVSEVDEFEADLKAPLNLSAFEWNLLKGALDKAIGRVNIARRRLALLRKEDDENRARAKANGGNMDVDGEAKSGEDDFFLAKSRSPFPEIETCFFLSDEPVPEDPALAVAVKAFSSLTREQKAALSRTLEGFVSCLAPSISSSHPNPKAREILTENSWHNRANWGKDEWIAWETWGWYRHFCRAYSPYLRNYAATFTAVSFARFEGQSDPASDLLQKIWDISIGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEQ6</accession>
    <name>A0ABQ8VEQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Histone acetyltransferase type B catalytic subunit</fullName>
            <ecNumber evidence="3 9">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_833097</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 9"/>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.360.10">
        <property type="entry name" value="Histone acetyl transferase 1 (HAT1), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019467">
        <property type="entry name" value="Hat1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037113">
        <property type="entry name" value="Hat1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017380">
        <property type="entry name" value="Hist_AcTrfase_B-typ_cat-su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013523">
        <property type="entry name" value="Hist_AcTrfase_HAT1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12046">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21184">
        <property type="entry name" value="HAT1_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10394">
        <property type="entry name" value="Hat1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038084">
        <property type="entry name" value="HAT-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone acetyl transferase HAT1 N-terminal" evidence="11">
        <location>
            <begin position="4"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4491762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="424" mass="49447" checksum="7986BE5D49E50C86" modified="2025-10-08" version="1">MSDWTTDSNECLSISLVRSAEDEKALTDDESYEDFHPAFTYPIFGEEEKIYGYKDLSIDLKFASGSLKQYLSVKWSDKLKSADTVDDVDGTIREFLAEGIEVNEDAFRVRVEEDATSFKPSGEMIYSYTRSASKGKGKSSVVEQHNPEDEDTVVYEVYHNTWKVPGFKEYHRKMQIFILLYIEAGSYINEEEDGWEFVVLYEKRKRRNAPHITTYHFVGYSSLYNFYYFPEKVRLRLSQFVILGPYQRNGHGSELYKAIYQYVLSQPRIGELTVEDPAEAFEDLRDKNDLKMLLSTKQFMEEGFGQNSYSHGGGRVGKVGKALSGSSRGKMGPPVEKGWAEKWRLKLKIAGRQFQRLVEMLIQMHLDPMDARGLRAYRLQVKERLYRFNFEVLAQLEKEERLEKLEETFKSVREDYNRILKLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFG1</accession>
    <name>A0ABQ8VFG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_840151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4483999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="48982" checksum="8353D7FD6E271B2C" modified="2025-10-08" version="1">MDSVPSSPMRGQNRSQSLNSPNTSPVRSKANARSVSSLCRTDSSHLGNKDYVIGISLLLVVVFLWTTSNFVTQDLFQDGYEKAFLVTYLNTSAFTLYLLPFLIKSYLPKITAAWRVKKTSRYDSGEYEPLHSEDVYADDDNSEETHRHERRPSGSSELPPFTVRETSDLAFIFCFIWFAANWTLNASLNYTSVASATILSSTSGFFTLGLGRIFHVETLTLAKIGAVSTSFVGVLLVALSDSSQTSSESDNLVSTSISIRHALGDSLAVFSAVFYAFYVILLKVRIRSESRIDMKTFFGFVGLFNIILCWPIGVILHVTGVERFELPSSEKAVGALLVNMAITWSSDYLYVLAMLKTTPLVVTIGLSLTIPLAVLGDFFLSNPVRLPVLAGALLVLISFVVVGVDDANAEQQQQDLVDASRNLVDDPDRRGRRRLSEIVELESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFR1</accession>
    <name>A0ABQ8VFR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_337826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="85"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="565" mass="63946" checksum="335BE07BEF3356D1" modified="2025-10-08" version="1">MISVHNLRMRIHQHCPLGMAPTAGTLHRREACSASFEMFEMRQCSVHKYKLKPVERLYLSPFTLHEFCKLPSGSVERARRYRNMTSPLNTFPPELLIQIFAIRPPQSIQFPPNYTQVCSRWRSIAYTSPELWTTLTIELLPALKTKADAAYLEEALTSWVLRSRSNIDLTVYGPFFREGWDRPSELQKRLYGKVNCKIIVKFSNKWRRLITPYTWDAHNFPHSLKHFSALEELKVAVGTCPLSTSNHSTFPKAPRLFKLNLDLPMSPSFACLESLIPETVSDLTLSSAPSMFGVSEDFMRSFLQLEQLQNLTHMDFSRVGWTTPHVLSSTILPHLQELTLGGTITALGDFLGVLTLPSLRKLSLSTSRFDGNGDHGPVVGPALIDLLKRSYRDKCGLLALSLTWMLARDINSGQAITLEALCHILSAASTITELHIHSEGHTDTARLMEILRYDGVSPEKQILPHLKCFSAESLSDLDQGYFLDFIYSRWWPDGSQPVVGVSKLEKLILSGCTLTEKTREQLDTCYNEAWEDMAAGSHIWVARGYEGLYKDDSSSAHCMEKVMNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG13</accession>
    <name>A0ABQ8VG13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PCI domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_896157</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="252"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="475"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="475"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4488649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="505" mass="56769" checksum="EE67D6352CEB5539" modified="2025-10-08" version="1">MKSTDKDENKDEKKQENKGEEVKKEPPTPLAEIKSNFVLIDRAVSTLEPRFTHRVLRTLTTLVKRLDETIIRNAIQEAYPKESTTKSTLISWLPTTSEDIEMQVDPTPTSAATAKFAAPVTSEPVPEVDIYLRLLIINQLLKSTEGVSKAKELSVETVKKMQALNRRSLDSIAAKVWFAVERAFELAGDISEARPMFLAAQRTAALRHDDDTQASLINRLLRSYLAYSLYDQADKLVSKTTFPVSAGNPQYARYHYYLGRIKTVQLNYSDAHTNLQQAIRRAPPATVAPGFYQAVHKLFVVVELLMGDIPDRSIFRHPVLEKPLKGYFEIVKAVRTGSLSQFQQTVLKHAALFQADKTHTLITRLRQNVIKTGIRRLSLSYSLISLKDICVKLHLDSEEDAEYIVGKSIRDGVIDGRLVHEKGWMACGGAGGVKRGYGADVAETFSRRIGYCLELHNQSVKAMRYPLNAHRKELADAEGAREREKELAKEIQEGDLDDEDLGGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH86</accession>
    <name>A0ABQ8VH86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="10">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_829671</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="10"/>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 10 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4494308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="416" mass="45719" checksum="34F60719860B0194" modified="2025-10-08" version="1">MSSSMLLRSLRLRGYFGSCGSASALPRRFYQTDTMTGEVVALPNIQPDRLQYTKTEKPRTPPPSKSLVFGHTFTDHMLTIPWSSLEGWGAPKIEPYGPLSLEPSSTVLHYAQTIFEGMKAYRDEHGNVTLFRPDMNMKRMNTSAARVALPTFDSDALLQLIKKLIHFERDWIPKEPGHSLYIRPTMIGTQKFIGIAPPSEALLFVICSPVGPYYPDGFKPIALYGTTEYIRAAPGGTGAYKLGVNYAPGVMPQKHAAQLGYTQNLWLHGPEHYLTEVGTMNLFVVLKKGDAIELVTPPLDGMILPGVTRDSVLSLARNHVSGNYKLPNLPNLIVSERPITMNEVQEAETSGNLVELFGSGTAAIITPVNRIGYLGKDIHIPTGEDGMGPVSRPIWTELVGRQMGSIPSEWSVPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHB0</accession>
    <name>A0ABQ8VHB0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_312782</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="55072" checksum="863AF06F8DB33778" modified="2025-10-08" version="1">MSQQSQLGESSHIAHPAYHPSATTPHFESNAYEHAIDSENEDADTQGPPKKKRRRQALSCTECKRRKIKCDRNQPCAPCTRRGEQAKCQWHVVEPVEKYVSRAEYDELKMRFDHLENTVHRFIAANSGIIKSGSVGAPAALGSAQHVTGTPLAGPDYPVPSTGFGIAGTIGNVPATRSPSPSSQNIATTSRFNLPTHHSSASSHSMSSRKFSIPQQPNTTSTYEFESATHHQQVQQGLLGSSSAPQFSSRRPQTHARQSSRSSVGSTGSHGSMRSPMIPQGGGTPKPNSPTLQSRIPPNESPSMTVSSPSLIKKSPLSLASITSPFDSEPGLSNRAGALPSEVLKSAHPISTQRRLTVSPTSNQSKNFCAQTLRLGERLRYPTLSIPIRHKPCTIPPHSPLSLLMVHILTTHSFIHHFLLAQHRVIAALSAVRSIQLAATLMPQGRIEEGLAIFHHLRSPYRQPIFHYFIVSLPKQDNPEFLRAWDPTQHCQEFIPYLLPHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHD7</accession>
    <name>A0ABQ8VHD7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_829828</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="400"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="543"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="543"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="704" mass="79079" checksum="2F433888BD1730FD" modified="2025-10-08" version="1">MSRPNILVLGLMNEDYLSDLFSPLMSSMRAVATVKSVTRIKEAKAILSSNTPPTAVLSIDAAPTQSKYRSLNEQLVRYARAGGVVVFGCNFSNHFSFDTAERFFRAWGVPWELGHYHRTTVYLNADGVQGMDLTGLESSYSVKALNLTQVLPTSAVYSPSQDSRTQSHVFAATSVDTSQTPAAYSAIGDGYLGYTGDVNAEEPTTKVIMAMLHLPTNQIVPDTSDRIVGVSFGPGGVMRQIRQSEMNARTTAASESPGAVSSSPQTEASEPNDSESESSSSSSYEKYEKGRRGTARGIPPRIVSSVLRPREAEVATRAVRRNQVNERKKAAAEKLKDKGNNVFKAGKYSQAVDFYKQACKTYKPLPVYMSNLAAALIKLERWDEAEMAADHAILVDPTLLKGYFRRGVARRHYGKPKGAVRDFERCLEMDPNCAEFKTELEAARKERDEENKRQGYNEDDADRYDVDSDYEAKLVFNLGRDFAPERTVHVLDCPSDSEEHQHKGKGKGKGVKLPCRYYNHKGCQFGKVCRYKHAPDDRSIRDELGRNVCLHFLIDRCKFGDQCWYAHEKMYLPSNGWWNEENLGGWQELYDLVKEDMDDGVFDRIGSAMNGTADIWRIRDNLDMLVDDWQNAADDGSEDDSDDDFYGLGMTRGRRARDMQFEREMEERAGNMGFTEDEVNELLCQGVKPWDDDAWDVLNALNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHE7</accession>
    <name>A0ABQ8VHE7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine hydrolase FSH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_980856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="23735" checksum="B0549C5496AA27B5" modified="2025-10-08" version="1">MVFSFLRPITQARSCFQRPISSFFVREPSSSASRIVPTPLVFVSATQWDQSSSRQGFAVLAQMYSEKGYTSLDADLSLSADASSVNKMQDFESELKSVVRASFNPFPPVFFARGAACLITQTYISSNPASGLVLISPPTSNHSLLSTSLLSHALPEFDFEPKFPITIVDTPQGMANLQVAGNRLAKDDRVDRIVVNDVEGQDAFVKIEQWMDEIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHY6</accession>
    <name>A0ABQ8VHY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_371325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="88" mass="10149" checksum="0E60850511AC2FF9" modified="2025-10-08" version="1">MICGQAILMILTHIVPFHPSATGCSNFLSNSLYALYQPLHREEIRRLRSPMTFDHLGSTNTQEELRIYQYLVRKFYTSILASDTSLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI04</accession>
    <name>A0ABQ8VI04_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="419" mass="46923" checksum="D9C0703EB49A651B" modified="2025-10-08" version="1">MKLRRSARQAMKLLTKRFPLLSDIHLNPAEVDVLAPRHVQLHQVGLLRHLTQHDNLQNTDPEFDILEQSLNASFSGYEEVDFEALEDLDNNRAAPGTAPMDKHMQEVDNDTGGTQTDSSEDWTPNAKSKKAPTRKRKRAPAKDASKSRKRSRSKRVGSTETANATSAPPFPTVLYKKSLPPQTLPEKFHALRPPNLSSSEWKTERKRQYNIWWQGRKHASSVEVHTVQDGFNIPQHSRISKPAWMGLRASADVRSSILEAIAGHGSNAAHAILEGITRIPYVAHLAVAVCDLNNRMFLYCSQLTPNILDCILPKVNAAIPNFVRSITRGFSEDDMQNNSRGDHWFSIAGHDRNNCQHPEATKFQKNNHLAIARVFSPGQIFHTLTPAQKLWLQYPASSISCHSTTLSGLGGLHEGKVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIK6</accession>
    <name>A0ABQ8VIK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_387129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="123" mass="12889" checksum="F02B149D3C462FC3" modified="2025-10-08" version="1">MSNDKLNGTSTIINNNAQNVSGQLSSMHPDISHIVSVLTETHMDSNADDNKDMSESDLAALFKQIDGANGVLNGVEDKLDGILSNLDTLLAVLEDAGDQSSGEGEAERAASQNEGKESAGDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIV9</accession>
    <name>A0ABQ8VIV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_918701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="39627" checksum="744D818051F07528" modified="2025-10-08" version="1">MTCSTCTVWRVESAGGGPADSDAQNPANVSVAFPAVHLPNPVISSLAIFHPSTDPPATFGTVTLFTLDVYFCTQVPGGKGTCTLVSSQSFPFILGLLESAHCVLADAPAAFGTISSFSFDIHFCTQVPGGKDTCTLVSFQSFLLILGLSESAHRVLADSPAAFGTMSSFSFDIHFGTQVPGGKDTCTLVSFQSFLLILGLLESAHRVLADAPAAFGTMSSFSFDIHFGTQVPGGKDTCTLVSFQSFLLILGLLESAHRVLADAPAAFGTMSSFSFDIQFCTQVPGGKDTCTLVSFQSFLLILGLLESAHRVLADAPAAFGTMSSFSFDIHFCTQVPGGKDTCTLTLQPLLERCLRSVSTFTFAPKYQEERIHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ68</accession>
    <name>A0ABQ8VJ68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_895116</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="5">
        <location>
            <begin position="47"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="4">
        <location>
            <begin position="200"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="455" mass="51372" checksum="0D7FB44E01C0E6B8" modified="2025-10-08" version="1">MEPISIAMIADFFHPDVGGVENHIYMLSANLIRRGHKVIVITHSRPPDRVGIRWLLPALKVYYLPIVPIASGATLPNFFTFLPYLRTILIREHINLIHAHASLSSLGHEGILHSHLLGVRTVFTDHSLFGFEDAASILTNKLLAGTLRNVDAVICVSHTGRENTVLRGELFKQSDDHPSRLVVSSNVYVIPNAIVAERFQPGPLKPTDTITIVVLSRLAYRKGIDLLVATAPRVCAAFPNIKFLVGGDGPKLIDLLQMREKYLLQDRIELLGPVKHNDVRSVLIRGSIFINTSLTESFGISILEAACAGLYVVSTKVGGVPEILPEDMISFAEPDEDDVFRAISEAISIVSARKHDPFKAHERIKTFYDWAQIAERTENVYDTVMKSEQRELWDRILRTMQLGRYAGPIYTIILLVDCLFFLFLEWWMPRENMDFVTHHWDHRQFAAIARSRTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJB1</accession>
    <name>A0ABQ8VJB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_826695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.285.10">
        <property type="entry name" value="Glutamate Dehydrogenase, chain A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050724">
        <property type="entry name" value="Glu_Leu_Phe_Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006929">
        <property type="entry name" value="PRK09414.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="188"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="457" mass="49157" checksum="EF9814704F7AF9CA" modified="2025-10-08" version="1">MSQLPSEPEFEQALSELKTSLGSFLKAHPNYQKALDIVQIPERIIQFRVVWEDDQGQAQVNRGFRVQYNSSLGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGLNMGGGKGGSDFDPKGKSDAEIRRFCVSFMTQLSKHIGQDVDVPAGDIGVGGREIGYLFGAYRKLRNEFAGILTGKGLHWGGSNIRPEATGYGLIYFIEHMIAKACPEYSLSKPSTLVAISGAGNVSQFTALKVIELGATVVSMSDSKGSLIATTDSGFSKDVIESIGQLKLKGGFLDSFKQFTDEGKYTYHPGQRPWTLLSKVHIALPGATQNEVSAAEAEALVKSGVRIVAEGSNMGCTKEAITIFEASRKKGGAGVWYAPGKASNCGGVAVSGLEMAQNSQRLTWSPEEVDTKLKNIMKDCYNTCLGAGEQWSGEENTGNDVLPSLLAGANVAGFIKVADAMKAQGDWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJZ1</accession>
    <name>A0ABQ8VJZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_256193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045166598" evidence="1">
        <location>
            <begin position="22"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="21592" checksum="F9511903A90D8662" modified="2025-10-08" version="1">MFAKIALPLLTLSAMAGNALAAPFNPKTQSLARRYTSFDNWGGLSSFSGFDNFYGVDNFSGEVSDQVVVEQQEEVVCQAVSIEVVQQKLLVLQEMAKQIISEQVCEVETQTVVFQQFLSSCSHFSSDLHRTSGHEVGYDSSIVSHYGDLYNADGSLSTYDLGFSGSDVGKSVVVPSGSNWNSATSPASVGNAFNAAVSAASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJZ2</accession>
    <name>A0ABQ8VJZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_761545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="101"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="37141" checksum="864128C496DA8E6E" modified="2025-10-08" version="1">MRASPFHVFPRHPRYTLFLLIVLIPSFYLLLPLRLDPPLTPLRFPPNESTDLAYRMAQAEVIYQKTLKDRDGLIARYGPHPSDLDMFPPNKSPWPAYTVWDYFPAAFNCPHEVRRIGLLGDGGKWVCGLSRLVDKKDCVVYSVGINRESSFEGDLLINTNYCKVWGYDPSVKGFAKQIPASERHRTTFHRYALAGVDRPASESEPAMYTLNTLMQMNEHQHIDILKVDVEGWEFDTFTNLIKSFAEQDLPLPFGQLQLEIHVWDKKFDYFLKWWEGLEEVGLRPFWTEPNLVYVNYAGSRKPELAEYSFLNIKGENVFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKI5</accession>
    <name>A0ABQ8VKI5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-P-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_828551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF14">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4495294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="339" mass="37794" checksum="1971918231258233" modified="2025-10-08" version="1">MSTKKLVLIIGATGIQGRPCVSAMLARQDDGTPSPYSVRVLTRDPTSEQAKGLASLGAELFQGSFEDLETVAAALEGCYGVFVNTDTFSVGQQKEIYLVIKMFEQAHRVPQMKHFIWSGLDYGSKFGKFDPKYRTVHLDGKGIVSDFLRSQDSSPSGESLTWSIITTGPYIENLGGVLLGPLAEREKDAVVFALPVGDGHVPAISVEDIGWWVRYAFDHRSETSGQELKIATEMMTMDQLVETFTSVTGIPAIRKLMSVEEYLGRYPQTNHSIIKGEKGPTIRETFAGMFRVWGDDLLTRDMDWIRRVHPTGYTLESWIREKGYDGTLSPDLRFFNSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLA2</accession>
    <name>A0ABQ8VLA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-P-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_828015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4495447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="35171" checksum="936A9CBAA5B10FF3" modified="2025-10-08" version="1">MKSTFDPQNDLTELSGKVIIVTGGNRGTGLATVKHLARAGATVYMAARNEGKALQAIEKLNHEGLQPGNGKVKWLKLDLSDPREAKRAAETFMEKEKRLDVLVNNAGVLSGPFEKNADGLSTMVVVNYLSPFVFTRTLIPLLTSTATEVNSDVRIVNLASIAHRFTPSGVKFSEIEDLNVQYRGKIMPGFMRYAHSKLLDILWTRSLQKHFNPVSPPIPIVAMSIHPGGVDTFSHDWPLPWFWKPTVALAINDAEHGSYTSVFAAAAKVVRDEREKYCGAYLDNKPVGRIAVPSMTARDDKLADDLWSLTTSLLKDLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLV5</accession>
    <name>A0ABQ8VLV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_902629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="294"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="563" mass="63086" checksum="A99521EC446B06B2" modified="2025-10-08" version="1">MGRRKLYELSDHEDDEVNTQSEDVYTDGRDSQGEEDEDGDVNPGKLDNVDADNNLDMEDWPRPPARTAQKQTLRHALASVNQVPVPRITRQTKKAKMQQDTVSTTEIQRLKEKTTRLQKQLAIANCIIEGKSRKGRENPVSAEEFEGPESEEDTQIMYSAVATPLPSMSTPKTPQLNLNRLLSTRKVSGKKPVSRNTFRNVITTGDVTSSPTSEMSATLVSSSSAPTMSASSCLTTSINTTTNTDTGSRAGSSDTQINITAEPSATLPLRANWQPGARAKTADYAAEGEAILLRAMRDFEARILGQDFFPDRATRLQWAEKCFRDACATAKAQFISDKHVLKLIATRGSRIRGQVYKWIRVNIVSCYKFDVTVGKRAVKQNIALSRLLSSRNFSGFSYKDREAWTGYAEHSSIIFLLSYIFDESNMGMVFEKYFNPISLQTLASLFTMIRAAISEWSSGTCNKVKKFSEEEYDKYYKAYLIDLTKWDGMNPAVSLNIRHRMYAKARIRMREDSSDDPTVHIVGSIEAQLRQEMEARTGETESEREDSEMDDDGDEDDCGGIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMP1</accession>
    <name>A0ABQ8VMP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_759285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="108"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="595"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="627" mass="70011" checksum="72A64B563E69A7A9" modified="2025-10-08" version="1">MLSRHSLAALSNTVPSRSLHARAGIPTNRHLYGRPETSAPSKQLSRKSSAENTVAKYRSKHYNKEPNPDGKIFLEPHILSGRLKKLCDRAQVDTAVAMLKNSPLDAQNVPVWNTLIWECLKAERFRLAHDLYIDMKRRGHRPNTRTFQTLMNGLARIEDWESHPKQLANAHSVHQAFMRHVDAVKKHDPSSAELSLAPTAAYVKILGATGLHQEIFDVFYSLDAEGRLAPDHLLFTAMFQALAMKPTAETGDFVQNAASAKLLWNLMTKALRRTKFQIDGQLVSSAMVALSRGRTIDQDFAFSLANEYFGLVGLDGVANSAPSEGKGILPLQPQSFAAILTLCRNSSRPLHAINFFGAVLQRSEFQGGPSIIDRAHVEQVLHSLIAANISSCSEKAIELIEWMLTQEIKLPSTAATKIRPTYPTFNLLISHICRAENDWRVAVKAFDLMTGYHCHDFMDGVEAKEPRIDHRSTGRNIPPTAEILSSMMKIAVGSENRANIRQALRLVHYFGIQSLAQPSHTLESKKALKDKLFYARKLARSAIEGIDILSSRSTSQDRPRDDDLVRWQSLKVEAKKLLGSESDNDFIPNIRRKQVHAKPREMREGAGTTQSNRLSKTGGRILNFKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMR4</accession>
    <name>A0ABQ8VMR4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Virilizer N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_918158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1272" mass="140696" checksum="5AC15E74292266BC" modified="2025-10-08" version="1">MKLLHWCSLIPEGPSSLAAIRFTKLVRVKCIRVFPKGAKPFELCPDIVSETKPDSFLLNVYFNAQPVQPSSESKDKQRAANALVPTTIAYAGGQIDFTVDLGTEYATRLMIVKGQFEALSLAIYGEVVSETIIPPLSVEELISSVSKSISSAETRTRTLSSSIDPANSSDPTFLARNLLSLIDDPPPLSLLSKLMFCLKPDNDDWDDSNFPFLFVDFDRDIFQTASKMEDDDDETVNSGEDQMNFDLEATLDAMSKAVSDAVAEDTLTKFAQVVADNIGPRTNNQAFHIAKLFKLSASQRPSLALALCQGIDVSTVFDAQSLDEDTLLHLLDASANADIARYLHNDYFLDVLADFQNSAINVTQTRSSKQAAERLATRIQAWEIFEDALSNTQADFAAATAFLRDIGTGEQSLGIWLASMTGHIDLVTKLAENPIVPNSSGVYPKLFVRNGIIGSMSVGAAISHDEFIAFVRAFIGVAGVLAVWAWSDSLGNDVCRERTLGVLRLWQSMDGYREIVNYLLLLRQFTLRLKWITSNDTPRKSGIFGEQILSDLLDEPEAALNDDLVQTILSLKQPLSHISENDRLSMRKIALVVEDGLPAAIEELVFPNTHPLSSRRLRTLLVSIALVEKELMEDLQKGDWNVLQMIWDEHSTALIPRLAELLAETSRDLNGNFRITSPFPVPHQTQPQTFTAVSLPQVLSQLFRLAEDLLALILYLVLVPESYPSSNPAPLSFSLSAYTLRSIVLSVVDVFVCTDAADTIYAQGTPACVSAQSTRQACLEFVRRASDSGPGGIIVEPEGGKSRAEIVMSMLLKHGVGSSGKDPAYHLLQMFALVDYVLPDPNFNAAVGGSLELDIEYEEKKQEWASQVLPNVLDEIQEFFRQLDVENKIHLLRRLVRLDSQSLIGTAEFLFTEEMRFFERCTKTLLASIELETQRNTNIQTVVLLYQIGLHVRLLGNMLQTRSDMLDWCLGALRTVQEAFSSLTTSLANLSIARVMSSHLDTVVKTLLVHCDSRFEDNKFRFTLIVLFLRTARLGDESAVEHNSVLSKAVAVLTTLPLESLDLGMFRLDIGQALANFKTPLSNSNLSTEISSAILSLMTWLSAQPSEEGLTVFCGIKSDRLVSLYDSMEASLTEEQLDTLNKLRTILTVDEDVKILPENMNIPDTLQLSMQELQDILSPLSSFLPIAPSTPTRNNIPDVLGLVISPPAALLRSPAATGLTKTYLNNDFRELRQAAVARQNTSRLPSMHGTFPTITIYAFNSRCFLFHSGCRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMS9</accession>
    <name>A0ABQ8VMS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_918578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="165" mass="19044" checksum="62368311F46979E8" modified="2025-10-08" version="1">MFARFRTVDVDDRVQLALLRKDSRRLHYICTVIGDSQSAFTDAFTSYPIHLRTFKIRGMHFVATKEQINKAIVAFSGTITTFIMHDSLRMSYQDFCGVLKSLVHCKMLRSLTLLSPAREYAHAAIQTMAYGDEEKAKPVFLQLIPSLYRHEPQYTSKASRPQEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNX6</accession>
    <name>A0ABQ8VNX6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calcium-activated chloride channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_894543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="574"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="7">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="165"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="748" mass="83822" checksum="CB1FD0808051F5C7" modified="2025-10-08" version="1">MDVDFVISFRASKKTSISKKQTKDEARKAEIQYSRLLETLSYGGLKAVGRRGDSLGHLLVFVSCPDKLVQNLIIRERQSDFLSGLPVTPITNGNESMPLAPSDRLRLVHAYITSIPSDGGLGVTPGSPEWDLVESIFCLHDRSFNEQWIHAWTTSKIASVSDGRIRDQFGESVALYFSFLDSYTRALVLPAMIGISFYFFGTSYSPIYSILTVLWSIGFVEWWRVRERLISLRFGTRGSFRVEKRRAQYDPKFSWWKRELRMLASVPVILGFAALLFALMTGIFVFEAFVTQLYTGPGHKFISFSPTVLFVILVPRLVAVFQLCAQYFTQWENHAHHSSYNSSLTLKTFIFTALVAYLGLALSAFVYVPFGEGLMRIVQVWLFNGIVPHTGSQMNANLTDSSQAPQKAEFWDVDASSAETKLNPGRLKDQMFAYTVTNQIVNTFVEIGLPYVLRKITAFRTKKADPSNGTGSSLGKKKVVFEDEKEKGGQAEKEFLDQARAEAALPEYDVFGDYSEMVIQFGYVALWSTIWPLAPVMALLNNLLESRSDAFKITVHERRPTPVRTDTIGPWLEALAFLSWLAALTNSALVYLFCPREHSQCTSSDFGGSESAIERVHRHLVSTAGKEGIDGIWGEHGKGLGATKELLVMALLVALAASHGYLIVRSIMRHIMERLLWKGSEEVKERERDERMVKEVFLKGLGGGVGVEVDMNGNGFKNVSVADRNVEGVGFWDHDEGMDEINRISKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP52</accession>
    <name>A0ABQ8VP52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">EXS family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_819506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="199"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="462" mass="52777" checksum="43375D2A22B9438D" modified="2025-10-08" version="1">MSEPDVDLEFGYSLSFPLPFRVFALTSLGILAWATNIHGLDNLGVDVVSALDLRVGDHHSPSQRYWPDSPRKADVTVLYKNVYRIFITYSVWCLVSWTTFRSLSQGNPTLVDVYGYIPAVFALLTVIILLLPFHVLFKPERDKFLHAIRRCISSSPDSPVYFADVVFADIFTSFAKVLGDVFISLRMLFPGNSLLEPPADHGWTRWIMPTIMSIPYLVRFRQCVIEWLSVDNTSRRPLANAVKYATAFPVMYLSAAQRLVVSDLINEKGKQAAEEAWHGEHPLFRLWLLFAAINSLYSFWWDVTNDWGLELLKPGSKTSGRPLPPRRLVLPHLHSGTALLGSHRPAPESEDHLAYPFGLRPTLLYPLPVYPLLVFLNLILRLTWSIKLSSHLHSKSEGSVAIFLIEVAEIVRRWMWVFVRVEWEVIKKARETRNTGRTSFSDTDEPEFELITTPTMEHEIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPV6</accession>
    <name>A0ABQ8VPV6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_758286</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046739447" evidence="7">
        <location>
            <begin position="34"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="18"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="486" mass="52457" checksum="02E33F3372755126" modified="2025-10-08" version="1">MSSSNTTTQLRTPLPKLQLLLLLLIQITEPITAEVIYPFIIGAVRNTGITHGDEKKTGYYAGVIESIFFLSECCTVYYWGRLSDVHGRRMILLLGPLGLTLAMLGFGLSKAFVTLVIFRALQGIFNGNIGVSKTVMAEITDSTNMADAFTMIPIMWSFGSTVGPALGGVLASPATQWPQSFGKIAFFHDYPYFLACAAAGLFAFVAFVLSYIGLKESSPRLKNKKPQNRASFEESEPLLLDGEARIDYGGSPPSTGKTDDDHPKPLSAWELLTPDLQIVLLNYGLLSFTDMSYFVLIPLIYSSSLSIGGLGLSPYQVGLILGIFALLNGFWNLLVLTKVLKVLGPRKMYIISYSSFLVTFPLLWILRDVAHLAGGVNALVWSLIVCQLLAASFVNTAYSNLIDFLDSMSLLIVQNAPPGALGAVNGLAQMTASGTRGLAPLFASSLFSLSLESRIVGGHLVDIVLIALSAVGLVCAFRLPKPTSQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQE8</accession>
    <name>A0ABQ8VQE8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_817180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="592"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="639" mass="71165" checksum="75D8CBA494252A88" modified="2025-10-08" version="1">MLPPTADADQEDPTTQIAWPNSRRRESDSSNVLDDEPQAPYEQDTTMPGKPKVLRKRLSTWDLITLSISMLGAQIVWTVELGYGTPFLLSLGISEQLTALVWLAGPISGLIAQPVIGAVSDSSTSKYRRRYWIILATVVLVVSTLVLAYCEALAAFFVDLFQVGAGDWDEKRTTRVANTAICLAIVAFYLLDFALNGLQASLRNLLLDVTPASQLNAGNAWHGRMTHAGNIIGFGFGFLPLAKLPFFRLLGGTQFRKFCILCIIILVITVWTTCALHEEQEREKKSSSQGKFREIWNNIKVAVLNLPKPIRRVCYVQFFAFMGWFPFLFYSTTYVGQVMALELGREPDPDLATRTGEFAMLLYSIVAVIAGTILPHLANRDRRLMAHKDDVDEDAELTRIKNTVRQWKAEAARNGKPLRLPMMPFLLRNIWTGALLWFSVLTMSTFFVKTVTQATVFIALVGVCWAVAMWAPFAIIMELLKELSENNQLPNDDRRPLHSRTHSTPGLRDVRFSERQPLLRRRSLDELGNDANDESSPRTPVAGGTILGVHNLAIVMPQFVVAVVTSIIFRIADGNTVVEGGDESDAYFGKNGVAWVLRFGGVCTLVGAVIARMVPPTPTEKAMRRRLGDMRDLKEEMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQR2</accession>
    <name>A0ABQ8VQR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_123689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="37646" checksum="E21E056C0CA7100D" modified="2025-10-08" version="1">MPGPSNGRKKRKSGGKTQRKRFIVNITSKYDKNASFGTPTQYTASASSSASSPSPEPSCVDIVTQIYHATHEHDRQPSIDLEKNPNHIINRPSPEYVQKSLSYPPENGIEYDSQIQLQEPYIYDPGNGPRVRDTRAFLASRYFSQPPALDDPLCAEFAQEEVLQMLQTVLPEELALILWYNKSRASSRICPACQRLYRVGDVLPDHALTGSAKSELDSLQRPSELEREQQLSGLCSSMCFILASFNQCDPRTTKAAWGHTVNEINDESWAVLNGGSSLLLKDGPGQNAAKALVMIVRMTRLDDLGLAQLCFPDVNWERFNEAEEEDKRTQLQEVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR76</accession>
    <name>A0ABQ8VR76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_790735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="185" mass="21572" checksum="BE25E9BE5AE37C39" modified="2025-10-08" version="1">MLPPYFTSLYRLFLRTSSASVLHQSSAVRNIRSLWRPVFTDAARVINKLQTKPSDHKQKSCQNWLKDWETQMDRTLSLLHASATSRGLPHQLTRNLSQLFHSEYERMSNRKYPVWNAQLPPRSHEYHTRTPDTTPKALNKEKNVRQVQYLEDRAWKALGFAVSMAEGRDKLSLGRVVVKGKLRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRT3</accession>
    <name>A0ABQ8VRT3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_789463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="31529" checksum="993B77117025F72D" modified="2025-10-08" version="1">MVPGTANEEPLRALNFTSEKGVPDAFEFPHITSIATGEPLQLKTHKVPVYNLREIEPKPSVDINGYTWETLPYPDLDESEGWEDRYATFTCEWLKHHLSARSCRAINYQIRRKHSDGDVSDNYQSREDIKDQQPVPAVHVDINRERASARALAVLGEEFTESDRLAIINIWRPLRGPVIDAPLALCDARTLDPADMERTTDAYGGGYFVRYNANMKWVYIHDQMSDEILVFRQYDNTLKPELGDAKCIAHTAFFDELREGQGLPRQSIELRCAVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRT9</accession>
    <name>A0ABQ8VRT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_864202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="entry name" value="bipa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048876">
        <property type="entry name" value="BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21018">
        <property type="entry name" value="BipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="611" mass="66128" checksum="DA4ECAD5772F6D11" modified="2025-10-08" version="1">MAGTTADSAVDGGFITRVMDSNDLEKERGITILSKCTSIMYKGNLINIVDTPGHADFGGEVERIMSMVDGVALIVDATEGPMTQTRFVLSKALSRGLKPLVVMNKADRSTSRPAQVESDLFDLFATLGATDDQMEYPLLYASAKQGWAQPEVPVIGAVPTEDASTDGDVTTHMTPLFDLILSHVPPPTHLTADGPFSMLTVQIENDSYVGMLYLGRIESGSLKVGDNILALDADGNECGGGKVKKIFSRIGMDRVEKDSATAGEIVSIAGIKMVKGGGVNVSLVSREGWGAEGPKPLMTTPIDPPTISMFVYPNDAPFAGREGTKLTSQVIRDRIYKEAETNVALKVLPGPTSEALELRGRGVLHLGVLFETLRREGFELTIGPPKAVMIPDPDVKGGKLEPIESCTINVREEYAGKVIEKLTMRKGEMHLYENGDPEEGWVKIEMDVPARGLIGYMAGEFKNDVHGEGTLNHYFKDYQPYKGPIDTGRNGSLISMANGESSAYAMAPLQARGVLFIHPQTDVYPGMVVGECSKAQDIYVNPCLKKQLTNFRSAGADDKIVMASPRVMTLEESMAYMADDELIEITPKSIRLRKSILDPDKRKRMGGGKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS08</accession>
    <name>A0ABQ8VS08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046418858" evidence="1">
        <location>
            <begin position="20"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="233" mass="26573" checksum="E0241C32A18CA9B3" modified="2025-10-08" version="1">MPRLCVIFIIFALILGVISSPVVHHNIASSVRLEGRVGETHTSLTDIPVKLMRETPFFNRTSRQTGWRLIGRNPRGANSNVGQYPDQKFSRERWTLFIGIDGFRVIRDSSGNLTPTRFSIPRKNAKRPNRSQPEAKSLPMLGAKVFFGDKRLKEMFFLELLEKPLDPSVRSNLDYLNHIVQIMLKRKMLYPWITQKDAALVPLDKSPAVWTEYLKKMYSVGGNAEGDDRGITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS19</accession>
    <name>A0ABQ8VS19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_85084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420:SF1">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="352" mass="38593" checksum="2B99BF744F7B1F57" modified="2025-10-08" version="1">MSSKSINFTPEGAVCISYPDLISSPLELQASIEKAFGSDPSSLGIIVVTGLPPVYAELRERLLKLAYNFSELDNTTREKYTDASSRYSFGWSHGKEIMNGKPDFLKGSFYANPVIDAPSVFEQYRTSYPEYYGNNIWPDTEEPGVEGFEQAFKNLGQFVFKIGCELAAACQPFALKQFSNSNISLPTLISTSETTKARLLHYFPPSNDASVSHTEDEPVDSWCGFHLDHSLLTGLCSAMYLEKTDPATEPNVVPSPSPSSGLYIRTRGGDLTKVSIPVDSLAFQTGEALEVATGGKLRATPHCVRVGGSPGVGKVSRETFALFMQPNVDQQLSPDITFGQFSKRVFEKHYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSH2</accession>
    <name>A0ABQ8VSH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_220502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12457" checksum="4154308205E0F11A" modified="2025-10-08" version="1">MCECASKLGLDGFIRTGVVYEIMLCDFGSVKLVSSQHLKSTPSTSTYMPAPSGPMKTPSYTVPITTFDAIQTLKLLGPFDYYPGLSYVQLDLTHFCVVLRHNTSSVVDCCSFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSJ4</accession>
    <name>A0ABQ8VSJ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_893853</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01786">
        <property type="entry name" value="RA_STE50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12573">
        <property type="entry name" value="AT09986P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12573:SF4">
        <property type="entry name" value="AT09986P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SAM" evidence="6">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="7">
        <location>
            <begin position="248"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="483"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="144"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="682" mass="73694" checksum="68A840966D846243" modified="2025-10-08" version="1">MSIANSDRRVSDWDENDVQNFLTGLGLPQYESQIKTHRISGDILCILDAEILKSIGIASIGQRLAILKAVYLLKISHNIPLDPDSYVPPSEAQDRTESVTVEKLHAIVKDQSERLRVLEEENKNFNSTLQSFLDDYNNLRQSFVSRSSDDSSPSLHRQPSFKWAQFKPTKSPTKPEHVESPHPSPQQLDHDIPPYTRSTPPSQIASTSASIPAPADKPKLQQNITDTPNLTQGAPPKPARQDSTDNLKSFKVSLEDPTWKVLPAALKKYRIHNDNWENYAMFICYGSPGNRIERCLSYDEKPLLLFQKLKDAKKNPVFMLKHIKDIRSPIVVAQQKHAARKASSVINSGNEQPSGAGSSTANAASTTAPGHTKASSRTITRPPRLEVNDLSAPAPLTSSGVGGLSPQPRWPEPGIASPMVETQRRAGEGGGDDSFLGIPPTSAGTLAPHGSVSNLSAGSSKLRLATTDSPPLSSGREMPVASVGVSYAVAIYPYMAEQEDEFDVVVGDTFVILSRAKGWWVVQRDPNGTGVVDTDLAKQGWVPAGCLLETNVPVASAIAEATAAKSATGSDTPVTSKTPILPLSIISTSFPGIALMDYKKKGEEELDLAKDDVLRAVKEEGGDRGWVPSWFIGKVAAVPPTPSTSVPPQMNNLNLEENNGQPQVSPLSSAFPPVQTRTATVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSN5</accession>
    <name>A0ABQ8VSN5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="34349" checksum="F45E38B8261723FD" modified="2025-10-08" version="1">MEPIDDLSSTITATLHIFDQKYQTLFVKLNSAIEDQEGVYMNLVHTGSLEHTAQSFSLQPKIRVLQLVLLKLRGQIIIGKHSEPLSNLTLVLPDADATCRLLYDALEDLATHISQAHYQNEPKLFKALVYCQRTPSRETQTAKISEMLQKLEKEVSFIATIAALVESRKYRPLSLVMEMRLPALFSISTNTVDVDLDQPDAGEDDPMPLAPLNPQTMPQMAPQVPQAHFHTQSPHPPQTPPPQTPPPQTPPPQTPPPQTPPPQTPPPQTPPPQTPPPRSEDFQMDDINATPRAPPDMTPRAPQAPETNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU07</accession>
    <name>A0ABQ8VU07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_914730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="336"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="639"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="715"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="923"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1042"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="447"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="510"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="650"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="923"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="963"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="995"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1015"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1307" mass="143336" checksum="FFF35BF4065EC5E5" modified="2025-10-08" version="1">MQTIDNAKDEIAAQLRFESFKLGKPLPASMTLHHQHKHSRSHSRNGSISSVASLPLTASKSTNSYDFAVLPTTNSMPVLSSKRNSHHRRRSSVSTRHESADIMGLPDLPASSSDDNIKDKDSVRRRALWALEGKQNDASFSKVEIPELSSPEVEKKMVDFSSKSFSTPPNPGYGKRESFKPSSSKDQLHTLVEEEEEEEDWDFQKSSLRKLPVSAVSLSNDDKLPITPVTPDDAFAKQIASRPRPVTLTLRPLSLTAGGLPTPSLTPSVRPGLRSLSLVPNDEQTTRNSFNDVSPTPHLRARPANLQISTSRGSVDETSCVIPIRRSSISYKSSAAAGLPTPEMTPTFSERRYSHNSLGSNTSVSGTSNDEDFLQSNASYSRHRPLSASEQHFLFKSHNALLSRIQDLEKALIVRRTSVSSVPGSRPLSSSFSVADSEDMSISSEPSDEMLRLVADLKAERDDLKRDVDGWRVRVGDLEKQIGLLGKRVEGERQEAWVARSRTNLLEAEKNTFAKECRQAKDEMARMEEEKNSEIAKLTAQIRTLEADKQRTIQENAHLSGECEYWKVEAARLSKMRKDEMVISTVRSSYDTENAPSAWHRGLHYDSVDSLESSTDVDFGSFDSDHGFGFSLKAVAEENEGDLDVHDSQIPEEDVEADYLSEEEDNGLAGYEDEEEEDFTFQSSGSSSSFGSIHEIPKPPSATHLQMDVLMPSSPAIRAPTLSSGSGSNTPSTLTPGSRSLTSSPVPSVASNIDAFKSTRVQATVASVHRSVGSLSKTWTFPRAQGASTSHDPRNDVDKFFDCLEDSETDSTGSRSPVSPSIYTYEHNKGLFAKGLEAFDDNEAMPFALPPNIISMVVEEQDSPQSLPVVIEEEEVEDDDEQTRVDDDDDIFGDNAGIKITLTPAAEDDNDEYLSSHIEYSYDEETDAEETDETAQQDRTVNVQDTKIHPRFNSTRKPVPVFEESDEGNDDDVPFEFGQPLRSSTPPHDLAMTTPPRSSVRISSPSPSSIPRPTLSFNTSTSSPNVLESSPTITLSKLPVRPTSSFVTPPTKRGGAMSSFIPLPITSSSPMRKQPSVRERPLVASFIRQPVRRPLMAANSTTSTSRAGHNDSNGSAIQSSFNFVNSSFGGAIVTNDPPRFSLNRSVPDSDHSFFTSPSFSSSQSYSGSFQTDIDGSHGFVPISTLVSTSTATNPVQPISTDEKTLQSSFSSPSLSSIMSSPKLSFQVIAGFIPRPWTARTSVSNVDQGDALQRVDLATTPADAKFKSYVSKQKQLERLKLRLQHEGSRTQCSFNDVCQKCDGAVVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUR6</accession>
    <name>A0ABQ8VUR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_811787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045677382" evidence="2">
        <location>
            <begin position="28"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27033" checksum="9A8B2AA8C7DA8CA2" modified="2025-10-08" version="1">MIHTRQSSLFFLSFFGLCLLNIRFVAARLYPTRPVNGTVYHCGKCDPITWVDDGKNPSMQNLGLLTVDLYCRGQYMFTIEQADPDAEMLMFCPPSPNDFQWPQNCDGYTLLFNGDNSSENSTIYTHDFHISGTSRAARFDIKNHTVDENPNLRTALGVSPPSTLSSTAFVNLPTPTAPASTVNERPQSSDTSATTVYADPLPGSNNANRPHHNSASSRGVDMEKLKFRFVFIVWPALIGISMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVJ5</accession>
    <name>A0ABQ8VVJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shikimate dehydrogenase substrate binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089:SF1">
        <property type="entry name" value="BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="SHIKIMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="37103" checksum="4BF635951DCCC781" modified="2025-10-08" version="1">MSNPENHTFYRLYGFPVAHSASPSFHNHIFNQLGGNKEYSLFSTSKVIPELLEEIRNESFGGSSVTMPIKSAIIPYLDGLSPESEASGAVNTIVKVPSPGGPKLIGTNTDILGIQNALLNQLRLQHPMISISSQASYSEGLGAGAIFGGGATTRSAVYALTKLGLHPIYLVNRDADEVKAVQDAYPELVKRESLIRLDHPDAVENFLAQPNSPRILMIVGAIPAIPPITKAERMVYTVASALFTLPYHPPTADPSTRNSLPIPTERLFLEMAYKPRLTPMLKVAIAHNWDGIDGTHAVVEQGFAQQRMWLRGDVSAETGSDTTILGPIIEQKARNLIAKMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVP4</accession>
    <name>A0ABQ8VVP4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arabinanase/levansucrase/invertase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_815112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04081">
        <property type="entry name" value="CBM35_galactosidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18821">
        <property type="entry name" value="GH43_Pc3Gal43A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CBM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045831787" evidence="5">
        <location>
            <begin position="18"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="6">
        <location>
            <begin position="320"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="445" mass="47720" checksum="5EBE42682DEDCED5" modified="2025-10-08" version="1">MAYKLLSVLSTIALARAAVIVPGASWTDTEGNVIQAHGGGFLKVDTTYYWFGEDKVLDSTLFHAVSCYTSTDLETWTRQNDALTPISGTMISTSDVVERPKVIFNSKNSEYVMWFHSDTSNYGAAMVGVATANTPCGPYTYKSSWKPLGADSRDEGLFLDDDGTAYLLYASDNNQDFKISMLDANYYNVTEQVSVLTGATLEAPGVVKRDDIYYLIASHTSGWDPNPNKVFTSSSLAGPWSAQVDIAPEDTNTYYSQNAYDMLLGTNGIYMGDRWDVSALGSSTYIWFPLSWASGLPVIVEADVWSVDLAAGTYTIATGTTYEAESGTLGGSSELLTDSSYSGGEAVGYLGNGGTLTLNNILGIGEAQWISLYYANGDSTWRNTTLSVNGGANVVIQQPSSGGGHVIQSVPVKVNLKNGANILTFSSGQANYAGDLDKIIVYTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW70</accession>
    <name>A0ABQ8VW70_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_817664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="18035" checksum="00887A7371CC0D01" modified="2025-10-08" version="1">MTPPRTKGRRPGKPKPQMIGLQHFLIQIPKHSHRRTITKLLCGDFTPQVFRASPSPLCQLTATENLNCLCHACVRHPETPQHILFQCPSLSSICSLRAEFITYIHQHRPVPFNAFFSDPDRPSLPQIIHLRLIPDYSDCKIRPQRHGPVAILLRHVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW78</accession>
    <name>A0ABQ8VW78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isochorismatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_812354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050993">
        <property type="entry name" value="Isochorismatase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119:SF3">
        <property type="entry name" value="ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="22165" checksum="819C4497AAF57D26" modified="2025-10-08" version="1">MANTTLFLLCDLQSIFRTAIHEYHHVVATTNKMLKFAKLFECPVIVTTQNAKALGPTDPQVELASLGILHRQTIDKTLFSMFIPEIQALVSELGTKTVVLMGIESHICILQTALELLIQSSICKISEVYVVADAVSSCNAFEVPIALDAMRHAGVKVLTSESIGFLLMRDASLPSFKEFARIVKESKGSTKAAGEALLQRTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWB0</accession>
    <name>A0ABQ8VWB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Flavocytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_893042</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="506"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="583" mass="62394" checksum="693540D6B32BE18B" modified="2025-10-08" version="1">MSTIVVGGGLAGLSAAHTLLERGANVLLLDKQGFMGGNSTKATSGINGAGTQTQQELNIPDNAKIFFEDTKKSARELARDDLIRVLTGRSGDAVNWLQDKFGLDLSKVARLGGHTHPRTHRGGAQFPGMVITYAQMERLEDLAVSQPERVKIIKKARVTKLIKDENAQVIGVEYTFNGKTETAYGPVILATGGYAADFTSDSLLKKHRPEYYNLPTTNGDHCTGDGHKMAMTAGAKGIDMEKVQVHPTGLVDPNDPEAKVKFLAAEALRGVGGLLLDNTGARFVDELQHRDYVTGKMWENGKFPIRLVLNGPASKDIEWHCKHYVGRGLMKRFDSGDALAKEFGIPPSTLKKTFEDYNQVVRSKKDPFGKKFFSGEWTYDDTFHVSMMTPVLHYTMGGLEIDDASRVIDTNGKPIPGLFACGEVAGGVHGANRLGGSSLLGCVVFGRVAGDSAAAYTLQATSAAIAKAGGRLGAIAGQVSGAPSASSSSSSASAPEAKGEQSSAGGKVYTMDEVAKHKDKKDVWVVVNGEVLDVTEFLPDHPGGEKAIMLYAGRDATEEFNMLHDPKVIPRYAANAVIGKIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXL7</accession>
    <name>A0ABQ8VXL7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_808789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="694" mass="75873" checksum="896267FF64DBC9FD" modified="2025-10-08" version="1">MNQSTSPESLHFISYPLSENDNFSDSDWLEIASNRESDTESVSSNNGAASSSHSRRSSISTDSSRSGDVEAWEGFLEEITDEVEAKINEFNPTNPDNEQSTSPFIDLDEDHVEERRVRDGLNQSLTSTLGASRISSHPSTVHNSLRDLRLSFPDPLSSSHDELNRSYDRVSSSEAASAALTEGGENDELGSSQVDMPEIAPIRDPGLPPTPEAPDQNALPSIQIHSAVRSSNLQVVLYGTSLRWSFVDELLRKAIVGGEIAGIDGSETEQLRPAIFDCMDMPRSDYNPDRPSLGIVFHPLADATIAEHTAYLPVVVCNNDDSFEKEFQEAQAAWASYHIPPHRVVRLEGSSNLSMFAAEDVDKLDPYNTHRAIQRIIRQEKPASWVGLFEQFNTVHAVTLFALLCVIAGFSVNTAILVQPMKGPAILPPSHTISGEGDGNQSSALAVRTTFSLSVIPASLNYVPAIYSRGAISASGASGPSSTAFPPSSRAEEQHAGPVTPLEGSLMKFSKEVMIRPSTSISAQASDVSSSLDPVTSTSAPQRPPSAVATRLVDSLSEILVTSMKALIEVVEHDLKDLMVAIDDLMLALHRSTSIVVEQFKSAAQSVREQLDYRNARAKDRARELKDKGMQIMSFAGNHILERTTDAKQTANFYKDLITSRRRQLKDKLKHGALRARHRARHHKSGIKSHRMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXW4</accession>
    <name>A0ABQ8VXW4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_752734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="54"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="282" mass="31155" checksum="397ED7769B720FBF" modified="2025-10-08" version="1">MTSNSAQEPTSYVPDSSGWSAALYNKNANFVYSPAYTTPVLELLAAKPGERIMDFGCGSGEVTVVIEKIVKGKEGGYIAAVDFSESMVEKAKTQGLPEAFVCDIQDLAFPPSSVYSGPREEFDAVFTNATLHWCKRNPSGVIRSAKRILKKKGRFVGEMGGFLNCIGIRTALKTVLQSKGYDGLERDPWFFPSPEEYSTLLKAEGFDVTHISLTPRLTPLEAGLYGWLNTFARGSWLNDLTEQEADEIIKEVEEMCRIDCQDGNGNWAMVYVRLRFVAVLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY17</accession>
    <name>A0ABQ8VY17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="19800" checksum="B8C56546EE542AFB" modified="2025-10-08" version="1">MGRGRATPTSKSARRSVARAPSASYARRHPMITRSKTVQVATRVISDPTPLSAPNATDVDSAIAFNADVINVSPPLDTISPTPLSIADPISSDDPTHHPLTDEDDRDDEFHDEVRMYLDYSSDILRAQAEEVKLLRREVASAREEKAVLKNKHAADVAAREEEYRCPICYELLWDPYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY22</accession>
    <name>A0ABQ8VY22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Legume-like lectin family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_811298</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07308">
        <property type="entry name" value="lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF45">
        <property type="entry name" value="RE50040P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045083349" evidence="7">
        <location>
            <begin position="23"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="8">
        <location>
            <begin position="39"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="38295" checksum="4C30D6EC57F951B0" modified="2025-10-08" version="1">MFLTSLWSSVLTLLPLIGLAQAAADTVPTKIGNQTIERTVQLRTHSLFAPYIDQDLQNRWWDFGADSYVNTNKHIRLTRNRPSQMGWLWSRLPLTSQNFVIEVEFKVSGDSGHLFGDGMAIWLTTERTQPGPVFGNKNEFNGLGLFLDTYANARHTFAFPRIMAMLGDGKTAYNYNNDGDGQEIGACSANYRRTNVATKLKITYVKDTFLDVKIQYQAWDEWTDCIYVENISLPQSPFLGFSAMTGDVADAHDVIAVTTSSAITSAITSKTSKSIPGTKIPGVSSSTWTGFFFKLFLFSGVCVGGYYGWMEYQKRNKYGGGMANFGGMSLSGGGGFSGVYTNPKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY78</accession>
    <name>A0ABQ8VY78_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_426812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="41196" checksum="12121C548039DD51" modified="2025-10-08" version="1">MIQNVSHTSQPSVQGWNPYATSTPPDFQAYLTSSSPTNPTSSGYTSPSSFSTSTAPFDTPPSGSISMLPLLWSEGYGNFDQGGSFGAIAHQPPFHSPSPESLQQERGAAVSSFGPSATSGVGHSGQQLPKTYPGYQSQVPWSDIVSEGQAQQFQSDFRFLSRTSNHQGVHAYTQSYPKAPAALITSDSRRSQKRVRSDDDEDGDEDSVRPSGKRSRHSGRDRSQNEVSTDSDTAGSDICHIIHEDGRYCGYLFSTDGSDRSKHLQDHVEAQIDARVLQFSADEKLIKARIHLQCRWQENQPSRCKPYFTGDRSLCRHYDRHLPPQERCPYCNKAFSKARIDCLNVHKRECYSTKVEQEKVAECRKGELTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY86</accession>
    <name>A0ABQ8VY86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_806657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="689" mass="77575" checksum="D1FB199B41B442FD" modified="2025-10-08" version="1">MTSSHARQDPFERTRAGTLKNLFERDLEYQWQLDLYKKLWGKDLGQSKPGNKRSVRIVVRRWPRAPNGTIISQLPEGFTTPSSTHLWGERFLDFFCLSRGTDWSAVHNQLISTSSRLSAWMKANGETEYAKDELMWAETEEPPRLRVAADIMEILNARDLLIMMGSCGVSLRDDESDIATDDDVNMEPELKSSTAPFDYPNYPDPWPLVPFSSNPTTLQSPIPFHLLPETLIVHDPFRLLHATTVRAQDVDWSSVDDITHKYSLNLTADSIKETIALERAKIQENMKNATPVVVATVFNRGDNPHSTDSPARSVPGDAYEVTVPPPPPPPLSVPEAHLFLSPAHSVGVGNHSCVYRVEWDLPRSVFSKPKICITCVEEAARKIIHETVTGTGDGSSTYSNGTLKLQEKRTPSLAFAFSKFDFDYAELEKSRAQLDENLLHKLEDDHKITYIDYTGSVSTIHVDTVPWYDPASTMPPPCSHLAQSSVSGSLPGSPPPTAQVSVVAKLSLPGDAHLEREAVNYQRFGTQFSQHWTGYTLARPIRNPTPMGAITPIFYGFYSKEGASDKYFSSILLLEDCGKPIEPLKLDIDDRQECAALVLRLHYHGWTQGSFWPRNILMQHGDHADFPLMKSAKDRRFRLIDFGRAKCLKDAQETDRVQGGDSRADDWDRQRFDEQSIIGHALDFKDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYG5</accession>
    <name>A0ABQ8VYG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_28541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required both for recombination and for the repair of DNA damage caused by X-rays.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="6">
        <location>
            <begin position="98"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="300" mass="32291" checksum="732E8CDEF3D6FB80" modified="2025-10-08" version="1">MSQDPQDSQIPENEEDFQFSGPLLVSKLQEAGIHPNDIKKLSDAGLNTVESVAFTPKKHLVTIKGISELKADKILAEAQKIVPLGFQSATEVHARRSELVHITTGSKQLDALLGGGIETGAITELFGEFRTGKSQICHTLAVTCQLPVSMGGGEGKCLYIDTEGTFRPVRLLAVAERYGLNGEEVLDNVAYARAYNADHQNALLTNASALMSESRFCLLIVDSCTALYRTDFSGRGELASRQTHLGKFLRTLQRLADEYGIAVVVTNQVMSSPDAAAGPYAGNEKKPIGGNIMAHASTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ51</accession>
    <name>A0ABQ8VZ51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_805120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF7">
        <property type="entry name" value="DRUG_PROTON ANTIPORTER YHK8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="54"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="491" mass="53694" checksum="A98D69299FF974E7" modified="2025-10-08" version="1">MSSPTSASDLESQVHKGKEVVQIVELGEEEKKYEVDLEPNEHPQQHTSFKKWTVILVVATSALCVTCASSAASFTEAGIAAEFHVPHEVTILSITFFVAGLGIGPLLTGPLSEVYGRNIIYRVSYILLCAFTFGVAFAPDIAVHLVFRFLTGLCGSSFLSVSGGSVSDMFENKEVANPMAVYTLSPFIGPVAGPLIAGFINQNANWRWTYRVLIIWSFIQTVALFALVPETYVPVLRKWKAAKLRRSTGDENYWAPLDKTNISLGGAILISCYRPFELVIRERMALLLNIWTSLILGILYLAFQAFPVIFEKHHGFDTQQTGLTFLGIGLGMIIGLATQPFWNNFIAKESEKNGGICPPEARLFAGEVGGILIPLSLYWLAFTTYQSVHWIVPIIASIPFGSGIFLVFTSVFTYLVTAYRPIAASAMASNSAMRSSFAAVFPLFAGYMYSRLGTVGATALLAGIMTLTVPLPFIFRRIGAKLRANSRFAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZM4</accession>
    <name>A0ABQ8VZM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome c oxidase subunit IV-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_892390</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase IV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00922">
        <property type="entry name" value="Cyt_c_Oxidase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004203">
        <property type="entry name" value="Cyt_c_oxidase_su4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707:SF10">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02936">
        <property type="entry name" value="COX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="181" mass="19587" checksum="9CDB5228090CA35C" modified="2025-10-08" version="1">MQAAFRLARHSTSVRSANSIRCLATTANPAHIASASSASSSSSSSKASIISLSNVEAQWEKMNAEDKSTVHEQLEEIMKKDWKQLSLDEKKAAYYVAFGPHGPRAPVSKPGDGWKIFAGTAALVGVTGIIYYAIRIFSPAPPRTINKEWQEASNERALEQKMNPITGIASEGYSGKGFVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZR5</accession>
    <name>A0ABQ8VZR5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 10">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_913154</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 10"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="568" mass="63345" checksum="C18C927E47F9D426" modified="2025-10-08" version="1">MSGKLASGNTFFPQHNCVLIIAPEYDSWKKLQHIYDSERSKLILKDLFAQDPDRFSKFSTDYVSTSGPDVTFLLDYSKNLITQPILDTLLSLVREAQVESFRNKMFAGEHINTSEDRAVLHVALRNFNDFQIQEAGTDEVASVLEHMKVFSESVRSGEWKGYTGKTINTIVNIGIGGSDLGPVMVTEALKPYSKRDLTAHFVSNIDGTHIAETLRACDPETTLFIIASKTFTTQETITNAESAKEWFLSSAKDQAHVAKHFVALSTNTKAVTAFGIAKENMFQFWDWVGGRYSLWSAIGLSIALVIGYDNFEQLLKGAHAMDKHFKETPLEKNLPVLLAVVGIWYNDFYGAQTHALLPYDQYLHKFADYFQQGDMESNGKTVTKNGHRVNYETGPILWGAAGTNGQHSFYQLVHQGTKLIPTDFIAPATTHNPIAHSKHHRILLSNFFAQPEALAFGKTEEEVKKELGSGASEALIKSKVFEGNKPSNSIMFPLLTPATLGALIAMYEHKIFVQGVIWGINSFDQMGVELGKVLAKNILAQLDKPEDVTGHDSSTTGLIHYYQKFRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0B7</accession>
    <name>A0ABQ8W0B7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-1,3-glucan synthase</fullName>
            <ecNumber evidence="2">2.4.1.183</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_750012</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19749"/>
            <dbReference type="Rhea" id="RHEA-COMP:11150"/>
            <dbReference type="Rhea" id="RHEA-COMP:11151"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28100"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.183" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058659">
        <property type="entry name" value="Mok11-13/Ags1-like_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058656">
        <property type="entry name" value="Mok11-13/Ags1-like_GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058657">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058658">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26122">
        <property type="entry name" value="CBM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26108">
        <property type="entry name" value="GH_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26114">
        <property type="entry name" value="Ig_2_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26111">
        <property type="entry name" value="Ig_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046110158" description="alpha-1,3-glucan synthase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="2375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1947"/>
            <end position="1969"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1981"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2006"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2036"/>
            <end position="2059"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2071"/>
            <end position="2093"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2108"/>
            <end position="2129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2189"/>
            <end position="2210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2259"/>
            <end position="2280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2287"/>
            <end position="2307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="2343"/>
            <end position="2361"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="11">
        <location>
            <begin position="71"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1723"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1727"/>
            <end position="1741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2375" mass="265074" checksum="5243B70C718A8265" modified="2025-10-08" version="1">MALFIGLLVLSSLFSLPSPNVVHASPYNEQLIQYNLNLNKTATSPLDYYTNRTNTTYTPSPSNWRSLPIYTVLLDKFANGEPSNDDFFKTPYESDWRETQLRFGGDLKGMGDDRMLDYLQGMGVRVIYVAGTIFLNEIWEADGYSPLDFSVLDPHWGTWDEWVETIDKIHARGMYFMADFTVGTMSDLIGFKGFLNTTAPFSLSEYDAEYLKPGYIPWNFTDYKDFQISNDRNTSCVLPQFWNDDGTLIVNITSNGCLESDFDHYGSIEAFGVFPDWQRQLSKFAGVQDRLREWKPGMVDKLKMFSCMVIQALDIDAIRVDKSLQVTLEALAEWSNATRECAIGVGKENFYIAGEVTGGDTFGALYLGRGRTPSMRPDSIATAANVTSSDAQYFLRPEGYNALDGCAFHYSIYRSLTSFLGMDGNLQDAYDLSSDSFITAWNEMFVNDDFINSNTGVIDPRHMFGTSNFDVFRWPSLSDGARRGMLGAFVTGMLMPGVVMYYYGEEQDFYTYDSTANNYLYGRQAMVSSRAWLNHGCYHLGSQQYFNMPLSRSLLGCSDPSVSLDHFDPTAPTRHLFTQFNFLRSTYTALQDGFTLTQLGNWTYEIQRPGSGGVSTEMGLWSISREGMQNVQVLNGTHNGTVWMFMTNENVTKSYDFNCSTNPDWIKAPYPVEPGNSTGAIVRNLLYPFENYTLQASLSPYFNDGNAPYFGCLESITMDPYGFKVLVVDSDWVGAPPVLTLFTPGHDARLLSASSGSNGLDNVDISLGFNLDMDCDSVTNSITLNMSTSGHGSAPLIGNVSCLSVGPFNSTGLSGVPQTAWVWNATLTNFPDGLLTITVSNPTSAVGVENGATDHLILRKGQSGNVMVFPDSDYNNSALTFADNEYKYTHSAFGADQFRYSMDFGQTWTNWTEWEDLTSVNTSFFAGSDMFWDGVHVMIQYWSQATMTTENVVHADAGGYTGPPRRVPQFLARGDFNEWGNNQGVDSQFTLNPASSSSLSTGSSGNLWELKIMAAWPTFVQLNVWGFDVADYYYGDTDGDGVLDRLPPNTEAPNYVNMSAPPYPYLSWSILVDDTTMRWTLQPRGRSAISMIVYSLLVSVPLITATLAVLIFMIAFYGVEHNKYGVALKSKYLPVFWDRKAQTVTDLNSELGLVDEKLVNAGHDKKGKHLAIGWPEDTNKTRRTVLIATLEYEIIDWKLKVKIGGLGVMSSLMGKAMTDVDLIWVVPKVKDLEYPAGDPDDPIEVVIFNETYLVDVEVHVFDHITYVIIDSPVFRAQTKADPYPSRMDDLSSAIFYSTWNQAIAATIRRYPHIDIYHINDYHGALAPIYLLPKVFPVCLSLHNAEFQGLWPLRTKEEMREVCSAFNISKKHCVKYVQFGNTFNLLHAAAEFVSLHQKSVGVAGVSDKYGKRSWARYPALWTLKHVDSLPNPDPTDIAALDEKPIKSKGVKVDRIAEKARPESKRQAQEWAGIEQNPNSNLFVFVGRWSKQKGVDLIADVMPGLLERDESIQLITVGPVIDLYGRLAAEKLSRLMEMYPGRVYSKPEFTALPPYLFSGADFALIPSRDEPFGLVAVEFGRKGALGVGSRLGGLGLMPGWWFPVESSSTSHMLSQLTKTIKMALKSTEEERAFLRARSAIQRFPVVEWRQRIEDFHRRSITISRELARANAWRPSDGYAFFEATNDPNEWDPEPEVYHTGPRSGISSRNSSARVSVEALVPITNTNEPLHLHPPSESHQDTESNRNSYISDPGDELHAALDGVSEAQQSTDYENFLERVNRMVARDRRRVPDPFLDGSSTRIRLGGHARTESSESIASIVETKSDSPLNKAIASFTDADGGVTAEFVTRLGNLNAKNSEHGLSIEKYLIKSEEAFFDKVRRKRLSSASASIKSKRSSFWGSSDSLSASSLPSTPAEAIPFNESMVLQKTPPEIPMNRLQIALSREIKGWPLYTLVIALGQMLSATSFQMTLLTGRNWQSSTQLYIIGSIFLVASTVWYPLCRLKPTRYALSLPWIFFGIAFFLIGLPSVSGSLHGAHAILSNIATWCYAAASAAGFLFFALNFGEEAGAATEIWVLRACIVQGSQQIWVAALWYWGYTLNNESASYTPPWWLTVIVWPLSFMSFSFGFILFHGLPEYYRQTPPKVSHFLTTLFRRKLVIWFLVSEVLRDYWLSGPYGLNWTYLWNVNMPKLHIFLLILAFFVGVWAVMLAVLSHFSKTHTWLLPVFAVGLGAPRWCQMLWGTSSLATYVPWGGNAGPYLGVGLWLWLGVLDAVQGVGLGMILLQTLSRLHVTATLAFSQIIGSAVVMIARATSPDGVGPGPVFPNLGTWNPVTDGLKGSPIVEPLFWVALGCQLIIVAGYFWFYRREELGTCPPIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1T7</accession>
    <name>A0ABQ8W1T7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_862743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="255" mass="28712" checksum="CBC3CFFE685C978E" modified="2025-10-08" version="1">MSLQPEFTATFSIVPYCHAVGLKQSDNADADDTNDRLSRVRSETLASDSSIDDDGVSDSVFRPTSPPLPPANFSFVASSTYIPPSTSELLNRVREAKRSGKSMDEVIHELQNEFYPLLPPPGYVIPSPSLYRATVAKLERLERCGGLLNSLKRELEDEENEDSSGTEDDLNAELEYVDVVAPIPLTKKNVASWSWRSSFWDYLELSVSISAGKRRKRQPEFDGDKEDDWAQRSVDEIKGRRLISGVRSRKRRRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W217</accession>
    <name>A0ABQ8W217_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_749044</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="72"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="338" mass="37948" checksum="2EBC18C0DBAA4F0E" modified="2025-10-08" version="1">MLQNTSAIRITRLARERELDLIFLSSTQYFQPGVSLISLPYDRRNYSLKSLKPVELDYTESIPSDCNRTEGALVLVHGLLGFKRNWSSLSKAFSRDLKRPVYAVDVLNHGTSPHAEPMDYLHMAADILHFIEKLGLSKISLLGHSMGGKAAMTLALDQNLPSGLLENLIVVDISPVKGKVSRTTISYIEAMRRIEALNLTGPNVRKEADKLLVDVEKDPSTRAFLLSTLISPSSESESARFRVPLDILSKSIPDIGSFPYDPGEVTYTGRTLLLKGKYIMFRFVNDDNIAIFRRFFPNSRLEVLDTGHWELTISLNRPNDFKDVVVNFIKSSETMPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZY20</accession>
    <name>A0A9W8ZY20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_564473</name>
        <name evidence="5" type="ORF">C8R41DRAFT_923854</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000035">
        <property type="protein sequence ID" value="KAJ4469398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZY20"/>
    <dbReference type="OrthoDB" id="407442at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037">
        <property type="entry name" value="ATPASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4469398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4474533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="152" mass="16607" checksum="A648DDFD14338E50" modified="2023-11-08" version="1">MEEGTKAKKTVFVGGIGDDVDESVIYENFATFGDVIEVQLPSAATNLHQQSEAKHRGFAFVTYSSTSDAQDAIDNMDLNELRGRVIKVNLARPMKTPMQLGGNRAVWESEEWLKQHVKPLNQSGGVQGRNAAKQNAGGEVVPSEDGDEIMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZYU2</accession>
    <name>A0A9W8ZYU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione peroxidase</fullName>
            <ecNumber evidence="2">1.11.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_522781</name>
        <name evidence="9" type="ORF">C8R41DRAFT_130864</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51220"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <dbReference type="ChEBI" id="CHEBI:34718"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:133977"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 glutathione + H2O2 = glutathione disulfide + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16833"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.9"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.9" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000032">
        <property type="protein sequence ID" value="KAJ4470398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZYU2"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000026">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="3" type="ORF">C8R41DRAFT_877197</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="KAJ4498819.1"/>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="96" mass="10244" checksum="ED8B376908778A04" modified="2023-11-08" version="1">MQFSTTLVALAAFVVATSAVSTSNLERRITDPGNPANLINCPPGGGADACNLEQPCSRIRVNYGSPQGGHYIWYNYDITDIPTGVEIGTEDSCTDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B125</accession>
    <name>A0A9W9B125_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8J55DRAFT_444825</name>
        <name evidence="14" type="ORF">C8R41DRAFT_848075</name>
    </gene>
    <organism evidence="15 17">
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        <lineage>
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            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
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                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000001">
        <property type="protein sequence ID" value="KAJ4495792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9B125"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="17"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4474147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4495792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="141" mass="14838" checksum="A1DB29B6AEFCBD6E" modified="2023-11-08" version="1">MSGKGGKSGKTGGKASGDGSSKSQSRSAKAGLQFPVGRVHRLLKKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKQRIVPRHLQLAIRNDEELNKLLGDVVISQGGVVPHIESQLLPSKSKGKKEDGISQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DJW2</accession>
    <name>A0A9W9DJW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_490727</name>
        <name evidence="3" type="ORF">C8R41DRAFT_869328</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000024">
        <property type="protein sequence ID" value="KAJ4474034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DJW2"/>
    <dbReference type="OrthoDB" id="3342934at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040855532" evidence="1">
        <location>
            <begin position="22"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4478902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="158" mass="15879" checksum="FAE1EF349F40BE62" modified="2023-11-08" version="1">MSSFLKLTALVAAAFVVGAQAESHTVTFQNSCGKGVPTLKANGVTLSTGGAYTSNGPLEAAIAYLDVGCGANGEGCTTIETTLVNPTSPGSGSSTDISLIPPHAFSVTSGFGYYNGCDGAGADCTNANCPTAFKVPTDTHVQVACQVDNVDLVITFCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWY3</accession>
    <name>A0ABQ8UWY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_985484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000143">
        <property type="protein sequence ID" value="KAJ4464275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="456"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="632" mass="68811" checksum="7FDB1885D21D75CF" modified="2025-10-08" version="1">MTDRKVREFWPGLDCKGCQEFAESHDALARDAAPVRIPDDDPARVLGIKPTTESVVFRAEFERLFALVPFNNVTVSASDSKKTVDPPRNKSPWYDTVYKEMEMLLVELGHPYPRELNAIMHWVTPIRNIMIQNWSQMVRHNLTLSTVTHFAKSFGVRRDREDGCATISSPDSADSPGYLLRRAARNLDAWMDALARSRIEQVPWTDIYRDTDEDDNDEDDTDEDDTDNGDSDNGSDSPDQGNDSAGPRGGAGAGGNSGSGSSGQGRSSGGGSSDARTKRSLEPTYSQGDNKRPRQHLDSQVVLNRLHLAFNCPGEQLLSDGFSHYFFIPTAESSTGVSGGAATNITAALPVSVPSGTVTPPRRGSLTSSLSSGSGTSSSDTDAFWSPTSTVSSIHSLPLSSPQSSPVRPKGITTTRSTDNSLTQTTLQSIVESLSATSLIESRPQNALSIVDHAGVILDTKVHQCTIGIVWAGKMYLEGLTSAPKPLHIVVKLADWERDSEAPEGSETVHGKVLRSEAKIYHHLVGSNIGPHFYGVFNNSGSIALVLEYKGKRLPDFGTLTDNSKHKLYDQVCNLHALGVQHNDLAPRNVLVNKEGDLTIIDFHQSELGHRCKGSRRCSELKDFAEQLQMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYA8</accession>
    <name>A0ABQ8UYA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_926424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000122">
        <property type="protein sequence ID" value="KAJ4465749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="38290" checksum="D0D5E49F3BE690FD" modified="2025-10-08" version="1">MDEPVPVQPSPFADRGLIGTFPPPYQSQAPSTSIIQNQLQPSKSPQFWDSGIMVVFSAELPPHHTILYRVLIDSLRCRSKVLDDIFGIPPSTQSQTQGTEVNPIALPASITTEKFESFLIGWNEFDDKVAANILNLLDISALLEADGALSYAMSKVVGLNLPAPQLLGLAWRHRAHPQVRDWIEPAVMGLLSTPLQCHNVEQESSIGLAYPIIAKARERIQEARLVLAAIPFQLAPRDILFPECPDELHQYCEKSWLFFWYQNITVELIHPTKPPLSYSGLVQLVEKTKFENLQEGCKSRTMERMKSYHDYPTVPDVFHAAVSDIVQLFNIPHESKCLLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYW6</accession>
    <name>A0ABQ8UYW6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_857054</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000116">
        <property type="protein sequence ID" value="KAJ4466332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF78">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="14"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4466332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="544" mass="60516" checksum="B9CCD7AD88E2953C" modified="2025-10-08" version="1">MSKSLSGRRLYRWINFSAGLAIFFFGYDQGMMGGVNTSPDYVRVMGLGTSSYEGPSEGYVVNITEPTKQGGIVSIYYFGTLIGCVLAGSLGDRMGRIKTMYIGCLWIMFGAALQCSAQNIAWMLCARVINGIGTGFLNAIVPVWSAEVATHTSRGAFISLEFTLNILGVVVAYWLEFGLGFVGDGRSQVRWRFPIAFQIIPVIMFMVSLLWMPESPRYLAKIGRVEDARKILHRLRSTDDNDNSSDEKLHHVADQELNDILQVISLEKKHAKMNNYWNMFWGIGSGDLHIARRVQLSIWLQIVQEWVGIAAITVYAPTIFAEAGYGARKAQWLSGLNDVTYMIATLWNVLLIDKWGRRVGLWWGAIGQGIALILAGAFARLLKDNPEKAAQYGGAAAFFVFLYTAIFGATWLAIPWVYPTEIYPLEVRAKGNAWGVVGWSIGNGWLTLLNPIMFNKIGENTLHIFGAVNFLTIPMVWALYPETANRTLEEMDLLFASKSPFVWAEEKNFRKLKAEMEASGKGIEEVVEGAGVTEVLNEDLDAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V047</accession>
    <name>A0ABQ8V047_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_927598</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000182">
        <property type="protein sequence ID" value="KAJ4463288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12400">
        <property type="entry name" value="RRM_Nop6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034228">
        <property type="entry name" value="Nop6_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF51">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="134"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="75"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4463288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="310" mass="34375" checksum="E3AFB75E800E0D2A" modified="2025-10-08" version="1">MNSSKLTKKQKKGIAFRSGKLGKGARKNDVGTSSNDTEYNSVPVLEIQDGLDIEDVEMENETVFSEEKIKDATVSAREKGKGKAIEEKADAVTVPPNKRKRGSEPVMEKVKDGEGKEKMFPRKKKKGNDEKQRFILFVGNLKYTTPIDSVKEHFSVCDPPPFVRLLTPKTSTPNNKSKGCAFLEFTHRNALQQALKLHQSRLDGRAINVELTSGGGGKSEARLQKLKERNKKLHDQRTERQGMNEENSTQPERYSATSGIGATPGAKKTWTVDDVGHGTVHRGGKKHNKKRDRSQHSNEWGTGVNAIPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1C9</accession>
    <name>A0ABQ8V1C9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_853331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16616">
        <property type="entry name" value="mRING-HC-C4C4_Asi1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="828"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="647"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="767"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="651"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="669"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="712"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="785"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4469142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="883" mass="96542" checksum="B70FA1FA8579DDD3" modified="2025-10-08" version="1">MAAELPPPQHTLLSPGLVSSYNISFNLTSLFTYPSRFLARLINKGDLESASAGLMDATTTSWIDSSETSSMAAAAATSTTTRAAKTATAVASTNAFPAPWGFFSSSYMCGLLIMGVLMHRIDNIFVPTMPTTFGHHHPSHNSHPNRSSYTGSLLNRFLPIDINRTSTRLAIHLPTIYLMCRVLLLWGIMLLQTAQLFPWTTHMYPLAESDSGNFSQNVLNILYRLGKWTASWETGDVCWHTFCAICAAFCVEGFVKGLDGNGFGLGFAEHMQANTSPFNLVGYAFLLHIYSSPLTHAFKAHKPDYNTSDVDPLPSRPDTHVLITLAIPLLQLTLFHLLSVRKRWSRHRLLPTALASMLSLMHFHVTLIKFMMSTPSSSLPSTLSPTYTEPITTPSSSYTLHASPSPNTISAYTYTPHHTTHGYPILNYIPNIFETLLISTIILTIFLNSLTQLLMTGRVDKPLLGLGVSSIKNLDEWKSMIPWEEDFGVVLLRVGTASLEATGLRGWGNEVGGVVASSLPGNSDDESRKYGRVRLTRMGVVGVTPGSLSQTQDKLGHGKISNGKGRGKTKLLKGWHNEVRDVDLGSPPSSSGSRRQWGINGILTLNAQWFIELGRFVRSVWGSILGAVNAGFTFGWEVLRGRGSYGNTRRRVQDKAQDRRDTGHSGGENEGESGSEDEDEVEELYRKFVRGESVSFGSDEEQDQDYNMSDTDQADEEESESQEEFEETPLLYADLSNRESTPGASTTTSTMIAHMSYTGSSPLTRNKYASLLKGPHGNNEPSPVGDGGNGGGRSGDALVKDDLQGNRISDSSASGVASGDPGDTRRNCVICTVEPRVIICWPCRCLAMCDSCRESLAARSSASKHRCPCCRRGVEGYSRVFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Z6</accession>
    <name>A0ABQ8V1Z6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="23676" checksum="715002CB2FB177F0" modified="2025-10-08" version="1">MEFCLALVQYIKIIDPLARALWSLEAAQTNAADVYLFWLAIFAAELKELFSLGEPVTGIDDALAGKVIKIFNAHYKAFIDNTPYDPYFTLFYLDPQFINSDVLKVSGTIPTGGPTITISLPVTDYVPEANEAPFPAAYHCAKKALKSILHAEVEMYSSIGDGASIFLLIQQAGGSIQTVVQKFLPQLLVYSCKEYPFGNLMGSKSMLDGGVSCYHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2H5</accession>
    <name>A0ABQ8V2H5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exocyst complex component Sec6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_777235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.70">
        <property type="entry name" value="Exocyst complex component Sec6, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042532">
        <property type="entry name" value="EXOC3/Sec6_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4470487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="749" mass="85417" checksum="A2D25C6FFC39052E" modified="2025-10-08" version="1">MAAAPVSAAQAIGEYLQSPDDLVKVSAYRKKLEKEKASIDARLKSGVKEQLQATREGLRKLLSTRANVQAIKDEMVIIDRECSDPQTQVATFDQISRVSMVHRNFVQTEEMVNNLLDMESKLSEIGYMLDDDSANITGPAPNLLVIHYYLKQLEAFRNQTMHQAKKASSDARIYLVRRFERLHTVIEQFDQYIINLAGNVLDIVREGNGHVIVRLIKIAEMEGREDEKAIAIRLVKKAAKLDAASKFKSMIANARVIKHYRSKITKAIADSIKAKFERAHKQDENDPMAFLENIQWMYADIIRIQSDVVPCFPAEYDIYSLYIREYHKALNVQINKIVASEPGANVLLALFEWLKQYKKDMRELEVPPDLLEPPLLDGKEQSLIEDYLQVIIKKLDEWSSNMMKTELEEFVSRQDPLEVDADGQYATQGGAGILFQMVNQQIDLATESGQGAILARVVAESNRVMRGMQEQWVKTVEQEYKTQVEKPEEIAPGLVEYVIALANDMLKSADYAEALLARLEPLVSEKYRVQMNEKLNDAIDGYLDVAKKCTQTLIDMIFNDLKPVTKNLFQPPWYDGILAQIVETIRDYMDDYKEFLNPSLFELLVEDLIDAFLLVYLNALANSPKLKIPAATERIKDDVDDAFRLFLNYKSQKDTEEYFEVLDLILGILEASKEIVFLSYWSFAKKHGPNLAFVEGLIKARGDLDRSGVSEVMDTIKRKVKDENLADPPEPTIMKKVAIQNAFSRFLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R8</accession>
    <name>A0ABQ8V2R8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046025583" evidence="1">
        <location>
            <begin position="23"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="120" mass="12894" checksum="AE8D97553E1E92EF" modified="2025-10-08" version="1">MRPTSPILFVSILLTIESLVGAAAPKQKIVINYDVRAYSNMDCINGYLGQFSGTATAGGFYYYDFPNSNCAVVYAVPTGCSLSVISLEDRDGTGHMTGPFSTGTKPRKVALPFDTVELHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V315</accession>
    <name>A0ABQ8V315_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="69"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="192" mass="21725" checksum="FEFCE6B57418112E" modified="2025-10-08" version="1">MSPKPDQSGMVEVLSQALKESQGRATRLEIELQSAVAISEDLKKQNLRLSQDVMKLSVPKHEPVEDSKVLVISDEISRLEENNAELRTKISTLNTKVEEIQEGLEAANKRKVKLEVSLTKVQEELKAGKERITELTSKYSQSRQKKKELQGELKAASERVDELEGSLIQLHEKYAKFKHENKEMQQASSNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V366</accession>
    <name>A0ABQ8V366_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_860459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7108" checksum="48BDD2D0E5A5DAC0" modified="2025-10-08" version="1">MCTPTTVTVASSFCVSHNAQLPSATASTLASTHSSETETIPDNYSRPPQCGHCGWRGDHAPNCPFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3F1</accession>
    <name>A0ABQ8V3F1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_851630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18724">
        <property type="entry name" value="PIN_LabA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="826" mass="90759" checksum="1062A552E202A0D1" modified="2025-10-08" version="1">MIRSNSDTTTTTSTGSPTPVSPFSSDYSVPSEPTSDETPDLGAFTAVLRAWTNLQPPLRTANSTLAQLANTTSSSSRSLATSSSDLREDKSTVWSHRPIANYLSLSDPVTTDAESTDRDRPRTVQIEAVDDDFYDHDNTNDDNDHDESDEQLRSQDLGLFDVEEQPSLGYLDEALQFIAAERERWTAQRETGTTAAMLTGIDPRRKRRRKRNKTPRAQSTTRTPTVSTFSSISTITASTALADDINDAEDADALGVDADDSSSSVEQQSSPLRALQSVIFSSTPGTPSRRARGRGRTRLLHSRSTPQLRLISHEHEDEDEEDESTDSVTEDSPRVQQLKLLGKKLEALFPEDREYLKKVRYRTMSPPRAASGSLQMSGPAGYLDSVDAEGPSKHVVLGGFVDTRGDPLKRTGKKDERLIHVFVDHSNILIGLLNYLRRYPRQHPQYRGSSYRNPQSQMPATSPLSSSPHSFSPPYPKPPKHLSHSALSLILERGRPITRRILVTSSPLYQPMDGAESLGFEVRIFARVPDTGDGMDREKGNGKQGYHKKSQSNESPYNSYSGNGAQGNVNSPAGDSSSSQSQRRQRNRAGSMNSNNNNNNQINNNYNYDNKPGSFTGVGRKKFHSRKISDNSSAESEQNGGPIGLSPGFMRSSGHLYSHSLPTSHTSTPPPFPNLNISTSLAPPAIITPSPVQQQRIRYREQGVDELLQLKLHQVLASIDGPPPKGSTIILATGDGNVGQFNEDGFLGGVRTALRRGWKVELYAWEGGLSRAWKREFGEGSEWGGTSKSNKKSQGKATQSGSDDDGPRFKVIGIEQFGSELVEIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4P8</accession>
    <name>A0ABQ8V4P8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="117"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4474176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="232" mass="25737" checksum="EE2F53CB145B74C1" modified="2025-10-08" version="1">MLSLLKLQPFKGLYLFYQLISTVLIRLPIWVLTSIPKSWRPRPHWMMRRSVKLKVVRHMIALTTTIGPLKLVKDELERWTKVSQVISIGIPGYWQHKQGSTIEVAAPPMPGEKVIYNLHGGGYITFSAHPSDMIAAIARGLLQHVDSVHCVFSSEYRLSSGEGVRAQNPFPAALIDALAGYVYLVNTVKFDPADIILVGDSAGGNLALALTRYLIEHQNSGLGRPQTLKCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V526</accession>
    <name>A0ABQ8V526_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="530" mass="55871" checksum="D34140BC59B4C28E" modified="2025-10-08" version="1">MTASVPSIPAATPVNVIHAAPVAPKPSTKLNYNSQSLQPKKIPRRSQPIINWFQRKLAGTVKAKRDSASQTGMRNLAIPGRPTNRITSSPLPSTVPAHVNRQQGRFDTAPGGRRNTISLNGDDDLRDSSISDSGSSDDESLARGSAWTPSRLEADEDASVRPLPPSSPPSPSPSRSSSSYLSDPRTFKSIAASTKPTTLLSVDVHGGMAHIAEAPLTPNTQVTRFPHVRTSSTSTTPILSSGASITFSALPPSPQSSSRPSSTTTAPQNSMNSVQAPLHTTHHPRNNPRPSSPPLDNASMLTLASSAYAIPGLRVGMGTPIGWSSAPPSAVGGGADSVSQFDGAYADAESQNDEEPLDDRDVDASLRALRPRSTRRGSWESEVSRWSARIQPSLVRERSVWTTNSVRTGALGTDQVHGPEKLDEAGNSPVVEGRPIAEDISSPTTAPSEAADAPTSPHLTSLPATKQASTPQEKLSSETVAQVEKPGVEKTPEPVVYLPKTGKTFAVTVDGSKEASEEIKDQYADTAGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5A5</accession>
    <name>A0ABQ8V5A5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_897360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08839">
        <property type="entry name" value="ArfGap_SMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044732">
        <property type="entry name" value="ArfGAP_SMAP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF14">
        <property type="entry name" value="ARF-GAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="3">
        <location>
            <begin position="13"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4475135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="389" mass="41229" checksum="515AD5C25A444C5E" modified="2025-10-08" version="1">MSRQDKATTERNAKTLRELVKIPENKLCADCKRNDARWASWNIGVFVCIRCSGIHRSMGTHISKVKSVDLDVWTPEQMQSVQKWGNRLANLYWEAHLKQGHIPPDHKMDSFIRSKYESRRWALDGPVPSDPSVLENGTPSKPVAPSAPATPVQQAPAPSQATHTPTNSISATRSTTSTRHQLLSTSLVNRPVGPVPTPSPPATAAPTVAAPAPAPQNDLFSLDFHAPPTRTNTTTDNSTPEQRKDVKQDILSLFSAAPPQSSSAMNSGFGQFSGAPAQAASPWGAAPVAAQAPVTSMMGSNGTGMWGTSSGWANAPAVPAQSNVWGASAAPAVPQQQFNLYASSNDIWGSSSTVAPVATGGSQDLFGSFSTAPVPKKDDAFGDIWGGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V673</accession>
    <name>A0ABQ8V673_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HlyIII-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_777870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4469816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="307" mass="35358" checksum="EB59E6A1E1B8B764" modified="2025-10-08" version="1">MSRRKLSESSTDSGTPLVGKPLKTITWNEIPQWQKYNKYIFSGYRRSQYTWGGCIHSVFAYLHNETVNIHSHLWGGVFFLYLLGTVRTELLTVYETTWLDSALFALFLFSAMFCHISSALYHTSICHSREVESRCHAFDYTGIIVLNLGSHYPLLYYGFFCEPHYQLIYILTITVLNLAAAFVVLDPEYAKPTHISVRTAIFIALGFFSTIAIVHLSFIHGIVVTLEHIGFRWFILSGSFYVFGALLYANRIPERFSPGTFDYFFSSHQIFHGCVFVAAYLHYIFITIALNHYHSQSQCRMLPQTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6K6</accession>
    <name>A0ABQ8V6K6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_845719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="279" mass="30818" checksum="14BD2573A165D0FE" modified="2025-10-08" version="1">MYRQGMPSSYGPQSTSGYDLRPSRRNRNTSGGTRPYSHQSRASYNSSTNVDDVENEFIEDRTPSFKIPSDFFRTPVGALEFEWFGEYPDTDEDVFYVQMPLPDGTEWKIRIFPSGRTNMSIFGYFLQPVGDDGVPCVPEGFKVRLALGGPPVESWEQRFNGCLNLNLPPVITNEKWYFKEGQKVVICKNEEAVGEITIPVNAERERERQRQRNNGRSVRFFPLTRGGFPIIGHSGGRSGGGHSSGGRLGGGHSDGGRLGGGRLSGDNSGSGPFAGTRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6L3</accession>
    <name>A0ABQ8V6L3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_592169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="50695" checksum="7499AB472A71BE29" modified="2025-10-08" version="1">MSRNFFLFPSLRYHRPTMSTASTKFSSEALQVVVFLVLSLGLCLTTHCLSRSVTTARQDSKISCARLFLMLVFASSWLFVFINQLLIFGITLQFNDTTCKAAAHVCAVLYGVSKAFMYLFLAEKVHTVWSPIDRRRFSSPQYKICFFSLVLYALPAVSLLSNSLHKIRVNDGVCVLELVHYAAYYLVAYDIYVTTLFTALFLWPLLNPSRRHPFVRRIALRTLCASIIALTSSTANAVIFVLLKNSEVGWVCFITCAIDVIVNSVTLFWVSHYGLQNDEHARGCSRSQSNASSIQFKSFFTTQNSNNLESKSSDVAAEMAASEPPLVPLRPLEVPIVDVNANQPHNGPVIQDKDSKVEEIDHHVSDFSPVSRSTDPEAAIVAIRTGSAYVDVETDEIDSFTGPQSVVFASMPPVSQTDPSDHTRTRSLSSSISSVSLPVLIVRGRVPDTGPSAILSGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6N3</accession>
    <name>A0ABQ8V6N3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_775363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02557">
        <property type="entry name" value="PseudoU_synth_ScRIB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="1">
        <location>
            <begin position="102"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="509" mass="57171" checksum="D04C0614552EA121" modified="2025-10-08" version="1">MPAAGRGLKKIPPYWYPYTTYAKQRWIGRELLEVVSTEFRDRSMEYYRYALDSGVTTINGQVASPNHIIQNGDRMENVVHRHEPPVTATPIRILLEDKEREFIVVDKPGSIPVHASGRYHRNTLVAILMSDFGYEKVYTVNRLDRLTSGLMILPTSSDCARKLTKEFVSGTVRKEYVARVNGRFPDGDVICEQPLLTVDRQMGLNIVHEEGRNAKTIFNLIRYDENTDTSVILCKPTTGRSHQLRVHLQYLGHSISNDPVYGDRRIWGEKMGKGGIDTIPSDERTAPAPPPHLANIQDNPESLLREPPPDDIEDIENVVIARTKLLPRETGEDIGMGSPVPLSSEAVGVITRLRNMKDEAEDWSRWRDVIFRAKGTLRAPRDLALKKPPPGNKKQKNKGEFVNEQLNAAMKDPAEPVQLTTPEAVSIAGELIAAASDANAGPEQFPQGPAAEPNEKQLYCPECYLPLHPDPVPEKLYIFLHALRYTTSLGTFETEMPAWSAEGFTWDMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Q8</accession>
    <name>A0ABQ8V6Q8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="159" mass="17791" checksum="8D28A9965824D16E" modified="2025-10-08" version="1">MHLNTIYLTLGLTMGFLAMAWTMPLSSNTVDRRALLIVDVTIEPDRNSQARQSLGLSGSSIRVPSERVRIGPNGVNFQVHSGSSLLGTGHLKANAFVVPQSEMHVEFWNNQHLYISEHSTAHFNIRNEEVVVIEGPHSDVDDMTHLLTGFYVNYNETHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V742</accession>
    <name>A0ABQ8V742_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046521">
        <property type="entry name" value="DUF6698"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20414">
        <property type="entry name" value="DUF6698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1309"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1317"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1374" mass="157901" checksum="6AD7FC29DD3192FE" modified="2025-10-08" version="1">MALDASVFGLEGSGSYHKALISHLDDQVKREIYSLKDCLTSVNGSTPMGIFTTNALNIELEVNDNGLRSQDKKYQALFLKTSQLQDIHLGQEITISYVDPFPPWHVRRTQLQSKWNLLCHCMYCDVPWTFPGAISQSNKARYELKTFFKKLPDWEQWCLDEKNKYVLIKMHLRAMQMREKEGLEGFRGVDIAGNSKDVAYMKHINVLVMCYGALANAKEFRKWVNKAREVKLAEGSDSVQAHVKVLDIWLHHQEIQNTWDLAAERLTKFRKTEVVVRYCDLEPESYELYYRPVWDWLQELLLNCDIVSKMEWDARRLFKFDGGSRTWKRFIEEAWSANSWWSFQVSEDAAHSGKADFVNFKNVVWHESAAKIFESMAEYCRTGYTMVCGDGVRRWMYPIVLIKSADYEEQCPIPHDQLLDFDNKYLERTAKDTIEILNNARQKALISKADEEAELKKYSLRPCFNSFFKLAHSDPYAGVSFDDLHFQDSGVWGDHIFEHAKIQINNRSAVTKIDNRNKLSVRFKEFPRWSKLNHFDTGVMKLSFNDGSKHYDISRLFLFAAHDVIPEKEDKAAYTLLKVMRKYINMIMYSGLNVQTSDTIALGHSAIKNFVDMLKVYISLSPDVNKTFNVIKIHYHQHLYDDIENKGVLCGMSTKPNEKFHGPLRKIYLRQTNFKDTAKQIVRFEHQSVVATLIQDEIQILDRYEHGNPELPSDLETPIDNVHFTLGSKLKPVSFAQLEGKDLIFARIHIRLAEFMLTLLTTATNIVRVTYTAHDTVIPYQFLKIRYESLETWRLAVDILHCNPNFHGHPRYDYIIFSGILGPVFAQLHYLLLCNACDSQYLIALVQAYKIINTRSRIDKDLGLLRIRKEHNLEFISVQSIVRGAVVLPISSETDDKFVWDPLDGDMFLRVKKYFPGFTDDEGNISDASDDPEFVPYTLPDLEKITMHNLRQALKKVQDQNQQLLGHNSKLRMQNSDLKSQLALAKRHKNLGKTVGNADPNVNHELVVKLAKKYTVMVYPWPTSNLFMSFPPNNLPDPESPERFKDESAFEAGLINELHLYLNDRDLRKKAAEYSPFQKSVFFLHQAKQGRSLALHTIRECASIIMQGINVKAAVWVTKANLLRRNSTTLRLQLEFPGSSAILRAIFFNKQSLTLDQYSFNYGSSLIGMLWGVKSVNDSSIALSAILVRFLLSDDTEFVPIGKNSQLNYKKNFYSYCAFLNGSKGTNYIKQLYSFFNQRVFLGMPSAAVCSTNDDHKDDAVTQALLAIRLADSCPADTSSLPSIPINIDTDLIPTQFTAMEVEHIDESWPPKDNLTEIPQNMSNGNVQDRGRGWGRGRSWGQGQDRSRSDSQIQSQEASVPAPVRTTRNQKRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7G1</accession>
    <name>A0ABQ8V7G1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_904722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046103762" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19323" checksum="BBE2F32E6B90EE68" modified="2025-10-08" version="1">MYFHRLLSALAFVSMVLSAAVPSPGSPTADAHQLLALRSNGPQLLSRNEATIEVEFPEDSADPRWTETTQNNANAGVIQLLRHAWKKYGLQDVKLKDVKFHGFVSGTDKRHSFSVKFSEDLPTFVDVGDCGGWVTVAFKNYAGKQEAVVSGSIDSNAGESISSIKSYRFGITDLDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8E0</accession>
    <name>A0ABQ8V8E0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein CPL1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_499066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048661">
        <property type="entry name" value="CPL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038955">
        <property type="entry name" value="PriA/CPL1_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21671">
        <property type="entry name" value="CPL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046104526" description="Protein CPL1-like domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Protein CPL1-like" evidence="2">
        <location>
            <begin position="196"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="311" mass="32467" checksum="B9D57E9FEA783F73" modified="2025-10-08" version="1">MRFAAFVLLSAICGASAEAIESLLRRGSTTEVCACISEDLRLDSYFGGRKVTAGVLEACICESEVSTFVAGNSVCKNGVDMIGKPVIEVVVTKLIKSTSNKQTCTFPEHSTPACTASNKCGFTCGDGYSVVKKNGQSTCACASPKSVCNGKCASSCPSGRSLPEKRDHLHWGQQTQRTCRPGWAACGIAGGGVRQWECIDIKSDLESCGGCPTDVVASDGKPGLGVDCTVIPGVSDVSCQSGRCAVEKCMSGYAVSRDGRHCVPQEVIPSDSSPHHIHHFDNTPTQKGTFGGKIVAAAAAAFGIEHLPFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8F4</accession>
    <name>A0ABQ8V8F4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EMC8/EMC9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08060">
        <property type="entry name" value="MPN_UPF0172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005366">
        <property type="entry name" value="EMC8/9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941:SF10">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8_9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03665">
        <property type="entry name" value="UPF0172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="2">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4470759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="208" mass="22595" checksum="F56E9297C252619A" modified="2025-10-08" version="1">MVNYTVGQLAYLKIFFHAAKHPHLQVNGVLLGKKVSGTVEIVDAVPLLHHWTSLSPMMEIGLDLAGKHAESLELQLVGYYQASERLDDTALAPVGEKVASKVKEGFADAVAFVIDGEKIGSDDVALIPFIAQSPSSSSWWPYAEPGSPAPFTPGSLFSLSSPDIPARAVALVRDQQLQRKFGDFDDHLENVTIDWLRNSAAMPSDIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8J8</accession>
    <name>A0ABQ8V8J8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Delta2-dienoyl-CoA-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_546669</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045002">
        <property type="entry name" value="Ech1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149:SF1">
        <property type="entry name" value="DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4475412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="31715" checksum="BA2ACCDC289F0279" modified="2025-10-08" version="1">MNNLSSKWIKVSEPFPHVLLVDLARSPVNAISTEFWKAYGALFDAISEETSDVRAVVLSSAFPNIFSAGLDLLEAGEIAKATADADPESTDAARIALDFRKQIKPFQEAITAPERCLFPVIAAVHGMVVGLGVDIISACDIRYAASNTRFTIKEIDIGLAADMGTLAYLPKITGNMSFIREMAYTTQWFPASKAEQIGLVSKVVEGGKEEVDAAALELAQIIVTKSPIAVTGTKRLLSHARDHSVAENLEYTSLWNSAMLQTKDMMETLASTKAKRPGKFLPLNFNFGKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8U0</accession>
    <name>A0ABQ8V8U0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha beta-hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_843083</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="111"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="5">
        <location>
            <begin position="471"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4479889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="65463" checksum="AB19F9B0A4809926" modified="2025-10-08" version="1">MPPTFTVTAAGENRLTKQNSLKRIIIISTVVLVVIFILANFWTHYQQRTSSLTSIALIPGEIHWKECIPAVENVECGRIIVPKDYFDAEAGTASVALARYKAKKFPRKGSVFLNPGGPGGPGSRLPITTGSALAKVIGEDWDLIGFDPRGIGSTMPPTRCFSSQISNTVLFANTVIEQGITVSSISDLSSPLLYDQLVEQHRQFLAVKEAHAHLCGEMMGNELKYMGTATVVRDIDFMSRVIEGEDEKINYWGISYGSILGAYLVNMLPHRIGYAVIDGIVNPVSWSNEPSHKWPINWISDAEKTYQIFLQDCSKAGPSSCPLCEYKDEPWQNLERRFEEFFDAIALNPIPVPFGNRPGVLTSGGARGLLVKSLQRPLEWPKVAKSFSSAMAGNGTALYNAIVRPLPLADLDSPEPHISPRLAVTCLDSPRPTSPDEFPTAEDLTEQGLKALREVSPHFGLSTGVSEPDGGCQYWPVDGPERFTGPWNATLETKMLIVSNTADPITPKSSGLLVNSLMPDSSVIIIQDGPGHCSIFLPSLCTAKLQRGYFAGEIPKNGTVCPVDLATFPDEESDKHIQMLSTEDRELLKALRDLEAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V935</accession>
    <name>A0ABQ8V935_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_922931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="263"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="698"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="798"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4477928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="998" mass="110177" checksum="20D7F0FFEE811AA0" modified="2025-10-08" version="1">MAASTTSNNSLDHFLSPLPPSTINSLSPRPQNLAAHYRPISTIIYPPSDSATVLDLSPPKSRRTSTLNRPLSTAFHTMGFLKSTKSKGKEKEERPIMLQKDSFFNRTLKPKKSLNSLMVLHEEFPQLSSTPPALYTPSLSSTFAESSTAGYSNASTPTATSASASSSTTLNPVTGSSENSSVVLDDYEYTHGDKYEAKENWITRKHRLKLHPYGADAPYMQSYDSVSLSADRYTHLLLRRLNPNGTPSFYDYVKNKKPIPSSILDLGCGEGHWIIDAHASWPEARIVGFDLVDVILPEVRNNERLHFVRGNFIRYPLPFPHSSFDLIRVANLSLAIPTERWNFVLSEIHRVLQVGGRLELIDDAFCFPYGKETVTPSPRARTFATAPNRRRRSSSKQNSSAFDLSDDDDDHDTGSSIDDHHTGDGIKDGQGQLGENSDDLEARDQGTSLDVDFVEQPSPTVDDGSSDCPSSPETAGDGLFLDVEDYQSSTSSLHDLDQEESKLSSLDPLSFPTSRQSVRPLPPARRPLPPLPTSPSFMNTIFTPPAKPCDDEDNLVTPTKLDITLPTPALVLNSAELSNSLPESLEEEQNVVSSPETTPNIPANRPSHEDTSEWANSANDGKALEAIFYNMLETKYGIHTRTPKGVTTFMKDIFGPDNVRKLRSMHLKLAPLELEELIPHTKRPKFRVRSLSKGTELDTRLESEGKFGVAKKHGKNGDGDMKKDKKSKKEKEHAVPFPSLKDPVTRSRANTAESHEVRPSSESGVLPTTLNAKAAGRLGIPYSALAVTPKTAQTTSPSIPSVHSNHSASSVASMSCVSDETPRSSSDTRTSFDAPEEPVPVQQSPGLLLLPSTFIPMPPAELEMHACKHMHTLLSCKRAIFDWLLYNDDGTDNDCVSEDSLRDAFFEYDSFRRLRLNWPSQTPEINTNDYDYNKNIEISFEGPKSSGSRSSTVSIDSRLSSTSEASIGPYNRHALTHVRTFRVYLAVKTRRLSSRAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Y2</accession>
    <name>A0ABQ8V9Y2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_461021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4483127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="79" mass="9299" checksum="F3C8DA26D5DB7548" modified="2025-10-08" version="1">MGGYVPQAGPLHNIYARRFFRFYSPIRIHYSPEPPPSTLQQMQRKLVGSRRRWAHRFVMLSRKISIGLQPEFCFPLAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA32</accession>
    <name>A0ABQ8VA32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_921784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="504"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4483979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="611" mass="66160" checksum="20F080C2F8C8D958" modified="2025-10-08" version="1">MTSITDRASLEAMKRADLQKLCKDHGLRANLKSEALIDLLLDTQQGTKQQPGQRSVPTRMSSRSTRTSSMIVHDLEGDEEEPVGGAEEEERMQPGVQEVPSSPPLPRIRKAKETQFRLGVGRPLAAGGKGARAVTKSVSASKAKKGKGSRSVKPSEATIEEEPESETIEPHRAGEPESTMSTEELPQTSPPNPPSAPAMSSEIDTHVMEALNPLYEQLKFLKAELQQMQSLRNELMQLRNRTADIDVWKQKVDTLSTEVEELRKKAALADSLNTELQELRELISTQRTSSPISEEAASGYRTPIMTRTALSIPRAPALMSEPQPSTSNNANYSSHPGIAPVMLGKRHRDSTGSNVAGVVEQGQGSGLSEADLAKTVLRPNKKRVKLSAGPDADGEDDSPRSPEETGEAPRGSAFTVFSGPELDDSFVDPPPPTTPLPAFYTASTPPNNNGPSRPRVTSTQGASENLPPFSFSFLPVPPTPGAGNPYSMPSFPYPEPPQSPTPVRDSNPTGFISNNRNRTDVFQAFGLPPPTRPRSRLEPALRTSSQDAEMGQYLNPAAFDNREGGESAARPEDSSDAMKRTMYGTELESETRFGDFGLEGVASDYNWSGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAK2</accession>
    <name>A0ABQ8VAK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF659 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_769648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24865" checksum="1594E495C5770EFB" modified="2025-10-08" version="1" fragment="single">KWPWILDCPDPCHQLNLMMKDIMVGSKKYPKIIAMRIVSAITTYFLHSNYGKYQLREELKNEPHQHGIQIGGATRFSTCATHVLIIRYSDAMEWCLSNGRLKFDTAAVSVPPICTIFFNVHIFRLRTCASTLPMGLITLEGQNTICSDVFFIFIGISIGFNRVFQDPTSNIFTHCQETFAIFDRRFDIFLNDCTKDMFILAYLLDPSELLLFRWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAM4</accession>
    <name>A0ABQ8VAM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="420" mass="48069" checksum="F51E4D5DB07DCB4A" modified="2025-10-08" version="1">MPDADDISSIRQDTLRAEIARLRGKPVTEMEKMRLYKVFDVVLDGGERVIARCERAGSDQEDPSEAQRRIHKHAAVLDALRKTYRIPVPLIYHIEPNPEVIGAPWILMERIPGGELHYVVSRWDKAVREDNMKIVLAQYAAIYSRIFDTLIPEPLSSMFAEELQHGHIDPMPTAFDIKLHYESFTSDPDILRARAYRQETATFIAHRFWAVMHDAEYCAEAEGHPDSELPVLHKLKALVPALIPSVEKYLELDNNGQSLLGSKKLHHYDPSVSNIMVDPATADTTGIIDWEFTTAAPALLSAAYPEWIRYDGQQSPTSHWSSHLLQLSPDKFEYRKWRETYEENVGQISPNYLKAMRAGRELQELVDWARFAITGWPLNERMAFLDSWANSKAMNFGVDVESVPVLRKKDWMCISIQAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB77</accession>
    <name>A0ABQ8VB77_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4477976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="56937" checksum="0CCAE6B2A8144E73" modified="2025-10-08" version="1">MCVDCPQSTSSTSMPTADADDSVNTGAVSATTTTSTAATSTTSADDFMDSLPPGWKPIVNHDNTAKTLSISLSLAFFICITMIFCVIWRRGKRRLKDVEKLVRKSKANSSDDLEVMIEKEVESKKRVLARATARWKANARYTFRQRRGKRRAVPHTEGDADVPPTNTTFTESSPSSPAHSSRSSVDSVLTPKADSSIDQILLSTLGEPPSLLSPPASSPPAYLHHPLSSNHHNIAPSGNITPTASYVQSRRTSMSSLTPDAHCINQPAPYSSSHHMAHVATDDKALLERLNQLVSAPDVSGLSTRHDTTTFAPVWQDEELSDYTELEEPRRESTSTEPVENTRHAYQYPSHNGGTMVFPPPPVLSISLNEKGKGVEVYPYEYSYHPDRSYGSSFEYEQAILDVEPEAGPSAPPFESTSGVFDTTPSAPPFESSENHILEHPRAPNLQASDDLNGGFVDGGSTVVETYGQNTSMGKFAALSEDSTRPLRTCVSVVSPEEFPLDGLLASHNDRDPNGRTFESSSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBA6</accession>
    <name>A0ABQ8VBA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_868420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045130">
        <property type="entry name" value="OFUT2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398:SF0">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4485147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="497" mass="56355" checksum="28CCDF10307FEFC5" modified="2025-10-08" version="1">MDFKSPSLRLSSDSEESLGNFVTKDAQRSTTRARRHNILVASLVLVVLSFVGIFAFLFWTPYSLRLSTPISSPHDNATSAILVDVEDEQTTVVPSVLDPWDLRLSLNGPPTAQFRENLKSDVKYITSWPGAGWTNDVMTYANMIYLGFITDRVPVVPMFTPSHINIGATNPVRPIAFGDVFDVPLMRKLTGKAILEWREVKDSESEEVDEIGCWNIWESVQYREHAPRGSAAPDHLKLDISYTKTPPWIKLIPDFEHDSHTTFWSLARLAFPQALNEDLGTPLPSPLHGVSRPPDAQMMCYDYMYYVCAQQPYEYETDYSPAWRYVAQYMHWVPSLQNLANVYLNRAFGVPEDGPTPPYIAIHVRHYDFADQCSVPLDECFASISVIARRVREVQDQIQAEKGIVVNHIIMTSDEKDEAWWQEVADQNWSTPDHSKTKELYGNWHPVLIDAVIQSGGIGFVGTWGSTMSIMAKRRVEAWHGGITRQVQWGYVGADDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBB9</accession>
    <name>A0ABQ8VBB9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_799068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045323006" evidence="2">
        <location>
            <begin position="21"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="58"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4479903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="441" mass="46372" checksum="142189339C9F6E12" modified="2025-10-08" version="1" fragment="single">MLSFLSSALLALALPRIILGQAKCGLVPPRDSTTPNAKSSTGTGSGSSSSSDGDFADVLANGWYPGWLADDNPPSNISWSKYNTLTFAFATTTSDVNVVALDSISEQALPEFVTEAQAHNVSAILSIGGWSGSMYFSNAMATSQNRTAFVETVLDLVEKYDVDGIEFDWEYPGKQGIGCNTVSSSDSENFLSFLQELRQDPQGAQLILAAAVSITPWIGSSGELMSDVSVFAEVLDYISIMNYDIWGSWSSTVGPNAPLNDSCAPTQDGSAVSAVKAWTSAGFPADQISLGLAAYGHSFDVSNSNALNSSKALQLYPAFNAGDQPHGDSQDAQAGTDECGNSTPVGGIFNFWGLVDGGFLTTAGTAASGIDYTFDNCSQTPFVYNPTSDVMVSFDDATSFAAKGEFINSMGLKGFSVWHILGDYNDILLDAVSSAMGIESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC32</accession>
    <name>A0ABQ8VC32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_837085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF162">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="396" mass="44021" checksum="00C0F83EA27C1582" modified="2025-10-08" version="1">MFYYISFLRPPPLQVLPSSQVTIIPQIANDLRTESFEDSQVIFYSWLPAANNTFLDATKPVELTTWRQANAYKEINVPSPSRIRDGQSWRLILSPVPQRYSINLEDAYGAESYLGKTPFPVISMPIKFTRDANQNRVKQEKIERYYSFTVPNVQSFPTSRVDLELRITEQTSFDLDKKSWDSGIGLSSWLVALAGNVDIIIRDPSSSVASQLRKVLFSPGPRKIIELGAGTGIVSLTLGALRSVLSMSEIKEDDGCIVTTDLPSAMPLLEHNVSMNSHMFARAAVRPIPEILDWDAELPLYAQTLLGQLDAIIMADVTYNTASFGALIRTLCSLIKLSPVDKLPIILLGYKERDVAERSLWSMAADVGIHFERVGARQGAGGAPVEIWMGQIQGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC66</accession>
    <name>A0ABQ8VC66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="61979" checksum="8DDF98021AC8AD07" modified="2025-10-08" version="1">MSKSRCAPTAGAAGSSQATARERTPVLPLHGRLRLIDFFIKRVKHRDTVSSGSNMPSDEEQTKNAKRRSGKEEFFPALSGATSLTLSALRDAAALAPIPYLGEAASLAIDIWDAVQTTRDTKASLKSLGSDAISLVYAVMATCDEVLKRHRQQESAESTVEDTQKLENENSQVDEEVDKDKDPSNPEQTTEEEKINPELRHNLERLCSTLTDIDAFARHVASRNAIIRFLTVRSDTGKVTEFQNKMKMALDLFTLQSNITLRQVTGRIEAQQTQVLQTLQSPVSPTSPTSEGANTLTFLSTPPTGESLHTLPGNALASVFPAIFSFAGATFRTGDTPVRHTTPTNEEGKGKEVVEQHGEESGGATVESSETTNEPEHAAPARNPVASSGAINFTSISGDQNTSWVNDQSQRWNYGNVYNAEEGPWLGTKRRTNGGGPSTREDQREEHESQRGSGRVEDDEYNDEVRFGRQTNPFVAYQPRDSIAGESHEWNQRYYPHDVPVAPMHNRSQIGFIPPETYYDENGVPTAIPRGRGRSGRRWRNERDHWDSYEGPRGGDYRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC74</accession>
    <name>A0ABQ8VC74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_423161</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053045">
        <property type="entry name" value="Zinc_cluster_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986:SF7">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="212"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4486871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="536" mass="57918" checksum="8E0888E9738629EC" modified="2025-10-08" version="1">MSNILATVSAGSSFAEGMVAARSGSVSVDDDAGIEESGIGSRKKKTVRRRKVNHACLYCRRSHMTCDEGRPCQRCIKREIGHLCHDDRRPKSDNQPPDIPPATTTPGFSTTTMYAPTAATPNRHQPTSTTGGVSASSWPMVSQSPFMYRSDTLGNEFSVLTDFLETLDDNSFFGAPQTVSSTLLGSGTSSFTTNTYAIPKNGSATATTISGTTTATESASTNSNSNQETSPSSNSDDPSTSEGEKASETQAPDPATILPAATKTEKFLLTAADQESGSRDERLSWVIRSKYEAGLLKPYNYVKGYARLSRWMDRNVSQESKQQILQPLSVLRPKFRAVAQSLRDIDLVFIEEAFERLLLDYDRVFSAMGVPACLWRRTGEIYKGNREFSELVGINGYLLRDGKLCIYELMAEESAVNYWEKYGHVAFDSSQKAVLTSCVLRYKPQLNINPNSPRNGPVGSSASGVMGAGIAGVSTSSSSGPGASLTLHPTASSNASNAGPVLTSTEEGLVNCCFSFTIRRDKWGIPSMIVGNFIRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCI4</accession>
    <name>A0ABQ8VCI4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C8R41DRAFT_868061</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Preautophagosomal structure membrane</location>
            <topology evidence="3">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018939">
        <property type="entry name" value="Autophagy-rel_prot_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF0">
        <property type="entry name" value="MANNOSE 6-PHOSPHATE RECEPTOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09451">
        <property type="entry name" value="ATG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01404">
        <property type="entry name" value="CIMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0072">Autophagy</keyword>
    <keyword evidence="17" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0732">Signal</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046183371" description="Autophagy-related protein 27" evidence="20">
        <location>
            <begin position="21"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="21">
        <location>
            <begin position="26"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="268"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ4487457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="430" mass="46515" checksum="A7BC73C27372FC48" modified="2025-10-08" version="1">MLTSWCWTALLYFFTPVSSAATTNDKECTVHSDDGRYYDLSPLSASKDYEFKTDQGHKIVMNVCKAISYESWGSDIPNTSKVGGIIEKERGSFSIGEKNTTLVLSSGANPKIVMENGSRCKSENGQSKNDRAGTIVEFICDTSVYGSGTPRLTAQWPPHNDELACVFFVEWRTHYACPTGERGGPWGFFAVFAILVTFLVMLYIVFGTLYNRYVLQLRGFDQIPQFSIEAMKYHGREALGWFRDMMGQLYEGGQGSGWGSNVPRTWGGRTNPNTGFGVGSQLPPGRANPRANTRSGATTNSFSHQAQVDIGGGGESTNVVDVPGGGVGGFVRPNSGTNPTNKQNQTKSTQPPAPLPISPAPVKNYEPGSSTAEERTFMLGDDEEEEDVIATPMTAAAPHPSEDDSNPPAASESAAQPRGRDLGDEGTIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCX2</accession>
    <name>A0ABQ8VCX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_406176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="42258" checksum="8D4227853C0797F7" modified="2025-10-08" version="1">MGLLPDEVDEPNQPDNYPPSPASNRSSALIFASCMRSNPRPERETTALMTWVDEIRPQFTLEPRQVRELKGMVMVAPSVETEPLKLHLLTHAAICRLENKSNANSDTASVKEVVDSAMKQLSKHVEIPSTSKEIIRTLGRDECANPARSSYGDVGKAVWARCKAEADIHDFSVFLSKTTHETAFKKVAEATGKKMLQQFRDDILATIVVDESGKKEPLNLEKATHVLCKKYVKGGSGGASHQFRFAMIRRFMREFECEEEGPVLKRRKIGNGGRQTQDEAFWGRFDKYLKEKMDSFGINLKDDKWKEYLAETVQADWQRFGQPNNSLLPALPFISNNAITAVRAPLQDIHDASNSGGSGNGTAAGELPIEQQSDYDHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD44</accession>
    <name>A0ABQ8VD44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_867861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wings apart-like protein C-terminal" evidence="3">
        <location>
            <begin position="226"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="636"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="650"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4489054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="905" mass="98711" checksum="C87E2338D6FBB1BA" modified="2025-10-08" version="1">MSAVRTYGRKGTKRNMDSGPVQGASKKPKIDSIVQPSTPKAAQDHLSHIFDTALPSPAPSTPNRLSKRMLGRSKTEPTLRDPKDSPESSSKSLLDRTSSLPSFTSPPKRFIPSPSEPSSSPQRPSPQRPVINHKRTYAGKSRSFLVAMPADQSLPEELQDDYNNRESYAVLRSRWGVDNSEDDPYPEPLSPLKSNTTTPSGSPSKGKGKGRLKQEVNVPADIIQPLRSITEIRNKGESRRFLDEVGYLLEGMGKDETPALKKASALEIISRLCEPDFVRQAKAADFLQSTWNAFIEAGGGTGEDKVLDTLIVAFATLVSRDLLSLTDLAQRVSPSSSTSSHPSFITILFSLVASLTPETDPLLIISQSSTPDGQLKRLGIMKTDRAILKTLHSVITSQAHIFHSKTPISDALLITHTLVAVPVELLSCAHMSLLLQSLRAQLQAAIDGLSSISGLANVDSASGITKPSSSSKSTLTTSYTSTILASLHLIPYPAIHALLALLDGYLLAQWAPSREIDHANCRRLLNEARDEWLADGLVAVGITAELSTTLALPMKRKDKRRTGMDASSRCTEIIFRVLVSLTHSDPLWGQTLTKNSQAMMFIVRTIVRADDFWGTIMAGARRSSISLLTGRTAINGKHNSKNTAKPTTRTKVEKVEEDGKITDYDSEDSGNGDFDQPTTASERSSLTRALDWLCLSLGLITNLVQVVDEAKIILRETMLDPECIHKTIPCIRVCSCRRPTSVLKLLVSTYEHQLPFISVHSTRPVVKIPEIPLTLETEQEQQAEADASFLLGHLSVLFGLLMMDSSENQDIVLDSLPLLHLGHEDVKPNPQTKHKMKQQKLGQLVENASELGVFYAVISRRGLSGNGIATGTPDPEQIHEESDAARGADVTKGVISFLRGLLDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VED1</accession>
    <name>A0ABQ8VED1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_371635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="17864" checksum="CF1AC52303A9451B" modified="2025-10-08" version="1">MTPRAAALIGAFYAVASSLNTILFTNTATSVLGYASVAGDETRLPIQTIIGIGLYALGLVLEWGSELQRLKFKKDPKNKGLAHTGGLFGLARHINYGGYVLWRVGSSIAAAGWIRGAAVGGFHTYYFLKDGIPELDAYCSKRYSEQWSEYKKTVPYKLFPYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEF5</accession>
    <name>A0ABQ8VEF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_372399</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046615432" description="Carboxypeptidase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4491663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="509" mass="56197" checksum="1A58059E70EE1CAD" modified="2025-10-08" version="1">MVVLLVLTLLSGTDARRMRKSELHARQQEAAKCFQDRAAPVTSGPHVERRSGVQNITFSNPKASEFWVDGSNFPEVDFDIGPSWAGLLPISSSPDETRKLFFWFFPPGPEGSLDDLIFWTNGGPGCSSLEGILQENGPFSWSWGTAQPIVNEQSWTNLSSVLWVEQPVGTGFSQGTPNITNENDLAEQLVGFFNQFLDIFSELKGKNFWLTGESYAGMYVPYVANFIYENPGIVDLNLKGIWVSDPVLGWDVVQEQIPAVDFVHKYENVFALSETVMAQLDATAEKCNYTGYVDKFVTFPPAGPLPLPGDSTEAARGCDVWDTIFDEALAVNPAFNIYRVFDVFPILWDVLGFPGSFPDVQLSPLYFDREDVKLAIHAPVDVDWTECSNVDVFPRGDSSLPPAFTVLPNVIEKSERSVIAHGLADFILIAEGARIVIQNMTWGGLQGFQTPIANDSLIVGGVSLGTSHTERNLTFVEVVQSGHMIPQFSPLAAFQVMQFLLGFRESPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFA2</accession>
    <name>A0ABQ8VFA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell adhesion protein byn-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_840673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007955">
        <property type="entry name" value="Bystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821:SF0">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05291">
        <property type="entry name" value="Bystin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4483134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="445" mass="50703" checksum="F3C3C8A4D02DC5D8" modified="2025-10-08" version="1">MPRTTKFPVKSRHNPLLAQLDDDEREARYGRISEPGRRQKLSKKFPEDDENVALDSKTSRRIFELAKTQQDELDALDEEIVEDAPQERMAKIVNAVDDDEDEDDGSDSDMREEMEEIFEIDPDDMETLDALLPHDIGERRTLADIIFSKLDENVGAIQKVQHKDPSKPDPALGLDPMVVEMYTKLGLYLSKYKSGSLPKPFKVIPTFPAWARILALTEPENWSPHACRAATRIFISTMNPAQAQLFLSVVLLEAVREDIRENKKLNVQYYEALKRALYKPSAFFKGILFPMLNQGCILREAAIMASILAKVKIPVLHASAALLHIAEMDYTGPNSLFIRVLIDKKFELPFKVVDALVFHFIRLSNTYKPRSRHESEHLPVLWHQSLLAFVQRYASDLTPDQKDALLDVIRATSHPQISAEVRRELVNSVVRGIPKERTHGDVEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFJ5</accession>
    <name>A0ABQ8VFJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_767620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4488646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="68154" checksum="E5013D2F0C6CFB8C" modified="2025-10-08" version="1">MTLNLEGFPLPTLDHLGVSSISPSDIDAKAITSDWLNQFATFSKDNDVEGTLSLFNNESYWRDILAFTWDFRTFIGTNNIKQFLKDRLSISQPKAFKLRDELLGVQQPYPDLIWISFMFDFEVGDIGIASGIGRLVPQTDGSWKANCIFTNLEELKGFPEKVGSLRNLEPNHGLWEALRRREAAFEDKEPTALIIGGGQGGMEIAARLKMLDVSALVVEKNARIGDSWRNRYKALCLHDPVWYDHMPYLPFPPNWPAYSPAAKLAGWLEYYAEAMELNVWTSCEVTKADRDEANDSWAVTVHFFDGRDHKFKGIKHLIFATGLNGNQPNIPSYPGMDTFKGQILHSSQHNLASDHLGKRVVVIGACTSGHDIASDYYLNGIDVTMYQRSSTYIMSTKAGWEVLFSNLYSEGALPTDLADRVNASFPLGFMMNGFAQRATEAIAEKDKEILDGLRKRGFKLNTGINGTGFGMLAWSKASGYYLDVGASQMIIDGKIKLKNDSLLQSFTKTGLKFEDDSEIPADVVIFATGFGDARNLIRKICGDDVATKCSPVWGLTNEGEIRGSWKDMGIPGLWYAMGNLAMDRFHSKHLALQIKAMEERKFGPRYSRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFM6</accession>
    <name>A0ABQ8VFM6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_902945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="179"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="326" mass="36628" checksum="2755F3C8229340A8" modified="2025-10-08" version="1">MSDTQEPQFDRLLAPMLFSLTVSAILFGVTIMQVLQYQRNSQRDPYVLKILVYFLLSETLPKKDVGHHPYGFPNPGMLLLYGSTFCKSTHTHPPNMFAIYVTAVNNLLCQMFMCWRIWVLWKDQRIFAVPLIFFIILLAISAVAVGFVYAIMGWHSHTVEGFETKKTLPLMYTAYSALILADILITSTLCLLLYHRSAQFKRSIIKIVTVYFISSCLLTTIMQFMVLISVIAWPNTEIWVGLFAVLSKFYFNSLLVTLNSRSPVDNQPVASTEIPLQFISGGQSNPAVISFQSQTSQVRCNGPGIVVGIDDVIEVVDDTGEKLGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFX5</accession>
    <name>A0ABQ8VFX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_399337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="434" mass="48634" checksum="9147E3E2BFDC83BA" modified="2025-10-08" version="1">MGEKYFGGDIKGSKAKSEPAQAQVKAMEKELEKPKEKEKKVEEEKEEGELKEEGELDQDLLPEPDVAKSVPLIVEEEAEEEEEGVPDGGPEDDGRSLLSASWGIGHDGSGIEVIDVEFVSRDVSLRSGLRNRSQRLFEYAERRAKMFARDDAKTQKKVPYITTSLAGRKRPRGAFESSHPIHMPRWGFGSASRPHPNAVALDTILEEDSAAFAGRTMSFGLSNEESSKERKLSEQRTLVFGKGAEIWFKYSPDSLRAVFSPNNDDLVERPMKRKRLDTNESPPPSKPHPSLLIKWDDSDRCCILRPELTGVTSLNASVYALFVTQQSLANDYLHYHLPDSIPRIPPSSSSDVLMKDIDTKLESSQLAAISASSVSPVRELIADDWVVEPYCVHTKEEHVWLLQPEVLEFIDSGITINKTRTLPVTKWKFILESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG11</accession>
    <name>A0ABQ8VG11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_832157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046930489" description="Protein kinase domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4492552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="365" mass="41890" checksum="6F56EE78EA59ED55" modified="2025-10-08" version="1">MEFSLRAFLVKLFTFRWVWPCIARFTPFRKTFSMVTWRDTPRNEVWSSYRSFFQSRGYALWVVKGYNLKPPNNNPRTPDGFSYENEHSANGPHGYGAGSPLHFPARTADSRDVFIVLLSDGIIGDNCVDTLRSIATGVNAAIDRNHALPMLQEIYCDNLVFGVFPLVGSYFAPAWFSNIAQVLEAMSQVMEGVAFLHDHLVAHRDLFPSNFLSSRRNGLWIPGKSQDFLRPRYYIIDFEWAVRFSPDSDPATRTVTGPPLSWDIYRRPPPPEMRSELPYCPFKADVWQVGKSFIRIVEHIENQIPEILEILRKMSTDRAEDRSSAREAVSQLNEVIARLPPQILQSPIEQVDDYSMDEGDSLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG95</accession>
    <name>A0ABQ8VG95_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoplasmin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_866945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoplasmin-like" evidence="2">
        <location>
            <begin position="92"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="43309" checksum="802F8F006EC070DF" modified="2025-10-08" version="1">MGIEGPRRLCNWLLSSQNLQGPLSGAESVWNVGYMAFDGEETKGLEHDAGYNHETYAMNISVPSSLSTSFLFSQSHGGIKTSHQRMWFNRSIVVDPNTKITFEELFPGVVGGWHRLAIRHAALTNKLNDSSFCRTTISVVREEEPGDKTLKQPTVLCTLVPMIIEQVRLDYTLALDRKAGYILVEGPNPVNISMEAAPSVNERVNGTGPNNAKTHPLTPLSTSLSLEKANFPGVDKSQCFYASTQIRDPRLSQRSNSGGSGSLVDTSNRPESSEKTSSSGPNHAKIQLLCSAPTSSSTLNRSSTMNLTREPRFYQRPNFSAVGDQETIGHRPSSVVLQAPSYKQSYLKDKPRYRRYRNYNANDHYFSSDHPPMKRREKYRFPNSMLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGP3</accession>
    <name>A0ABQ8VGP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase C14, caspase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_831029</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="4">
        <location>
            <begin position="44"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4493411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="43777" checksum="FE99D16AFE3C98DD" modified="2025-10-08" version="1">MHFHHSKEAPSGLDPAFGAEVSLETTRTTTTREEWISSHCTGNKKALLIGINYSGTDSSLDGCHSDVSRMYKFITQTYGFLAENIVVLKDSSKLEDEYQPTKANMLYWMQWLVKDAEPHDSLLFHYSGHGGQRRDRDGDEIDYKDECIFPVDSIPITDASDEQILNAHRNVIIDDELHLCLVSPLPAGARLTAIFDSCHSGSVLDLPFMYSAASGKLKEGEFIAELDAEKAGKMRKGRGVLAVEKTEKWRIKEKVFEMKDVLEATKDILHETGEKLFVEKDAKGALMDLERLNGVKAHVKQVEKLEKRNESLADIVLISGCKDTQTSADASEDGVPTGALSWGLMSTLEENPEPTYLQLLDGIREKLRREKYDQLPQLSTGHPVDLSTTFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGS7</accession>
    <name>A0ABQ8VGS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Symplekin tight junction protein C terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_980889</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021850">
        <property type="entry name" value="Symplekin/Pta1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032460">
        <property type="entry name" value="Symplekin/Pta1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022075">
        <property type="entry name" value="Symplekin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245:SF20">
        <property type="entry name" value="SYMPLEKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245">
        <property type="entry name" value="SYMPLEKIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11935">
        <property type="entry name" value="SYMPK_PTA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12295">
        <property type="entry name" value="Symplekin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Symplekin/Pta1 N-terminal" evidence="5">
        <location>
            <begin position="104"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Symplekin C-terminal" evidence="6">
        <location>
            <begin position="968"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="441"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="485"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="586"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="790"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1202"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="796"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="817"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="830"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1224" mass="134721" checksum="A435D42281E21402" modified="2025-10-08" version="1">MASNPVDPLQTLQAALNTEPNSKEQADLLASLRESLEAQPAPIRVLVPILISRVVNAGDSLLKSWVIDLFHYGLCRSSLSLDVKTQLSSQTLETLFYLLDDPNPATVKVVTQCLATVYPLLFRSLCANRNNPAAWNLLSSCKSKILGFVGLPGVNLGVKISALKFMQRIILVQVPQGVSDPRLQNKNDPNLSFCPANHPFISVTQLEAEGQLLLKTVIEILYSTQNVDLLSALLNSWPTLVKTRPNMMHLVVAALKQWTPAAFNGLSASTIKSAEKAVRILLTHILRLPSASQFIPQINEALATQASRMEIAASEEKKKRAAAAAGVTDTRKRPTTEADRTDVKRVKLEAEPPAPDPSLSLLASFDFSTLPATLITDLIVANLEAFTEPALVSLVQVYRQRLGIGTVSTSVPPAPAVTASGSVPVAAPAVPAVSDIRSVGKDIARPPTIEPPTTTPAPPIKEEPVDPLQMDIDQDELEYEPDRLNEELSGPVPSLKTALQSDSAPGTEEQPINLSLSEFKLPPPKDIVNIDDRIDLISKSITRIHEGAAEMQSSTNVSTDSDVTIGGPMDMWMLLVVRMFTRVAEPPDLDRSNDGEDTPMDNEEDKSTPLYERQDRLRRILCDYIMSDFPGRIRLATTWMNEEWYNDQIRLERNPKWRPNYDIWLGQIVASYQTHLDGKDRTFARFLLDLPSLPADVVSLLRELCVDNESPDKMQIGFSTLRGFVMQRPLMRSDALNVLLELTTHPEKKIRGAAINTVKLWVPNHQPMDSMIREFALQILRKLQREPVQEALAESNGDSTEFNVNGDSAPTVAREASFAEKKRATKVTDELEEGEDENMEDGQLPAEDLLQTPYLPERIELPAEKSHVLQHVELLFALSVKVPDLLDDLFAAYGQMDITVQEAIQSLITALVRSLGSSHGKLLTLMRTCPPGAESLALRILSIFTEHGRPSPQLVALVKGLINERDLDARFLIPIIAEMDKPDIIRHLPRIVSILDGKLESKTLVRSVFSSVVTTPPQTFGSVTSNMPRVRQSELLTPAELMVLLHDSEKEIGIKSAKEAIGICFSMTDVFRSEILAVVMQQIMDEPVLPVLFLRTVIQAVTTYKSLVGFVSTTLLSRLITKKIWTNPLLWEGFIHCAKVIAPASFGALLQLPKDQLRELVDKQPSLKAGLRDYVTKKAPNKARVSGFLDIFSESTAVELSVEGTANGGPPRTQPEPGAGSGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHK8</accession>
    <name>A0ABQ8VHK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_953152</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STE7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4491876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="33454" checksum="418107570FC6E1EC" modified="2025-10-08" version="1">MGNGGSVMKVQHAPSGVIMAKKIVLIDAKPSIRKQILRELHIIHTCSSPYIVSSFGAFISEPNICICMEYMDKGSFDSIYKSIGRPIPICIVRQAAKRVLGGLVYLYEAMGVLHRDIKPSNILLNSEGQVKLCDFGVSGELENSVAKTFVGTSVYMSPERIQGSDYSVKSDVWSLGITLIELAHGCFPFADTEVDDTAPSATLSPTTHARRSRRKSKGVSVHGGVGTLSILELMHHIVRELPPALITPSIPHSKDFAGEAAQFVDHCLRKNPSERMSPKELLAMSWMDDEGREDEIDLRTWSGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI80</accession>
    <name>A0ABQ8VI80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_765742</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0943">RNA-mediated gene silencing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="19"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="353"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="15">
        <location>
            <begin position="556"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="12">
        <location>
            <begin position="947"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="12">
        <location>
            <begin position="1110"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4491773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1383" mass="155571" checksum="6FB9E91ABEBD9507" modified="2025-10-08" version="1">MTSNVLVTELLPRKYQEEIFTQAQQGNIIAALDTGSGKTFISTLLIKWIAAKNNDGRKIMFFVPKVPLVEQQGDFISQHSSLRVLKLHGSSNIDISDRNGWKLKFQQHDVFVLTAQIFLNFLTHSLLKIQDVALLVFDECHHARKKHAYAIIMHEYMQCPPGKRPKVFGMTASPVWNPKNPAASIRTLETTLDAKVIGVRQHIDELAENLPKPTEMIVFYPPPPQDYDYPSPLLWDALNVFTLLKNVDLDSGSWADVERRYFVTLNNLGPYAASSYLFSEASYLITRLFAIYRLADDSETNELVVPRSSSPKEIPSELFDIADVLVDYQAYFTKMDDPSSLPSSVSLDWCTPKVRMLAEVLRDHHSPTFQGIIFVEQRQIATYLAKILPHIPKLNGIVKCGSFVGGVATSERVSSDGGQEQVARAFREKKINLLVATSVAEEGLDFPACDVVIRFDSLDHVVGYVQSRGRARNKRSKFIVMIQEDDYAYQERYQKFMDTEPKLKEAYQAQLQLFQDVLNPDDDDDDEEEEESAADLASRERYMVPSTSAFVTYDSAISLISHLCSFIPHDLYTTQPAPVYTGDFQSTLRLPASLPLPPEALVYQGPIKDSKKEAKRAVSFLAVKRLHELDVFDDYLLPAGSRRGKDFQDAEGKPVPDMSHVAYMMDVKVRDPWVISKKMWMHPIVIDGKVLAGLITGTRIDRTQIDYCDGIVKTEPGRLLELHFNKDVECLRMMEEYTKLGIHLRISGSPFVGRPSLLLVPVTSSMDIDFQAMEEFVSNPNGNSDWSVIGSEHYDRLLVRNVNQYGRIWFLRSIRNDLTPMSIMNVTPEGEVQTYRDYYVDKWKRKNDRNKWTPVVPETGPMLQLSKILRSKDTQYPLAGSGNLATDSSSKLAGTVLIPQGCCSWLTMSNEMSRAFGLLPALAHRITDIYRVRAAKLELRLPPILDDLMVQALTIPSALAGYNNQRLETLGDAVLEVCTTVHLLNQFPYRHEGQLDVLRQRSISNRFLLYRALNVGLERFITSENPRIKAWRHILEENNDELSPSRCASRNYPRRSLQDCMEATLGAAFLTGGMQMALQTGNTLGLMFGGPSPWSLRYSQVESTPMSPMFTKLQELLGYNFNNGRLLREALTHPSFSSAAEVIPSYQRLEFLGDAILNLVVIHHLYNKYPTADSAQLAFPRTKAVCAQALAFLAVKKLALHHMILLNNVDLSQAIDSYVPHLQAASPQTIIDNGWRFDPPKALSDVFESVIGAVLVDSGYNYEKTACVTEFIMEDILSILSPSVRLDPISTLMQWISSSVCQAQIKFIVASKGEREGMQVEIHGLVVAGPIVSTSLVVAKNLVAERALAILQDSCHQYCLSRICDCNNGDFAPLEGNVMRENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJE8</accession>
    <name>A0ABQ8VJE8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_762072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="166" mass="18707" checksum="04C0615AE021E11B" modified="2025-10-08" version="1">MQTHLQLRLKSKKWGVLLYICNDLMVFPAQILNEIARKALVAKSDITKDSMVDTLRLNSIHEDQAFVWPHFTRTDIAPPRAPWASPVLSCTFHGNVACHTLTDLEQKEMMQDMARKMNWHCAAGVGHIHQLLWAPCDDSNVGKEKLAKSLNAEGIDALLYVCADLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJQ5</accession>
    <name>A0ABQ8VJQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="837" mass="96087" checksum="8FC614DF1F91EA54" modified="2025-10-08" version="1">MTVEEVTDDGDPSPGMSRNHFTSIDFSGAGAELGGETGKNGFQRFKDTKHEKSEEMWSPFKSHKEWQLARWLMLSGIQDELHSSFKDKRTFLKKIDALPTVRGGWICKELEIVGNIMKKAADGTEVPMTEEVELWRRDPIECIKELMEDPRFEEHMRYAPERMFTDETMHMRAIDEMWTGDWWWATQKLLPEGSTIAPIILASDKTQLSTLSGDKSAWPVYLTLGNIESSVRRKPSEQASILIGYIPVSKLECFSKDARSVEGYRLFHDCMGMLLEELIVAGDPHKGGVKMLCSDGKIRFVFPLLAAYVADFPEQCLVVCCQENRCPKCTAQEKELGDPLHSILRDPDRTIQSLQKAANGDNTSAVTLGLRLVTPFWASLPLCNIFHCITPDILHQLHKGVFKDHIVKWSTHAVTGKSKKEREREIDIRFQSMPRHPTLRHFKQGISLITQWTGHEYKNMEKIFLGVISGATELEEIILSFNIPKVHSMNHYTLMILSIGAAPGYNTEWSERLHIDFAKLAYRASNRRDYIKQMTRWLDRREKVLWFTRFLDWALEKDRIDWLATREVDEEENEEAVTIPDFGEALQVEGIRTNLQYGESTCMVAKQTPITNITIESLDSDFGCSTFVYAMERFLREQNLLRSDYWDAQPAKYSLYKQFWVIVLPTLEISNSSIVDVVHATAAQPAVLSGRGKRKYTPAQFETVLARKSLPDSREDLDVLGKDGLHVAQVRAIFDLPGQLGSFPHPLAYVEWFTPLRKLNKVTRMYRVEHSIRGKIRNSSIIPITYIARSCHLVPFYGKHANPTWSSEKVLDQCEHFYLNPYLRPIDFVLLRPKDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJR1</accession>
    <name>A0ABQ8VJR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GDP-mannose transporter</fullName>
            <shortName evidence="5">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_830213</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="40913" checksum="F49D834D7D3A0FCE" modified="2025-10-08" version="1">MASTLNSNNSSIERDTAELRRALATSPSLDNNVQLSAIPPILCYCFASILMTVVNKFVVSGANFSMNFLLLCIQSSVCIACVTTVKKLGIISFRAFDWQDAKTWFPISFMLAMVIYTGSKSLQFLSIPVYTIFKNLTIILIAYGEVLWFGGRVTGLTFVSFIFMVFSSVIAAWSDVSNAMNDAIPTAGMGSIHDVKDVVQKLNIGYFWMLVNCLTSAAYVLTMRKRIKVTGFSDWDSMFYSNLLSIPVLALFSIVVEDWGTENLNRNFPTETRSFLFMAIAFSGAAAVGISYTTAWCVRVTSSTTYSMVGALNKLPVAASGMLFFGDAVTFGSVSAISVGFFAGLLYAVAKNNQKKAESRMHSEGIIPLTSRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJX9</accession>
    <name>A0ABQ8VJX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_826143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zinc-finger" evidence="6">
        <location>
            <begin position="1209"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc-finger" evidence="6">
        <location>
            <begin position="1392"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="942"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1018"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1319"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1860"/>
            <end position="1903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="517"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="953"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1328"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1865"/>
            <end position="1875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1903" mass="208809" checksum="38CE00E5F0D48FBA" modified="2025-10-08" version="1">MAFTSYSSLSNWDGDEGLFQPKSTLTSKTSSTRDSPQTVPQNESTSECTSLEVPASKQLSIDQGVSSSEPFSALEKCADVPNLDAIDNEAESVDTDTETAVATNMSERINSSLFTPPRRESISPLSPSSPLDGASLFSPRESPKSSTSTLSPLRQQTENYHKKKPGEKFDPESYHGYGTGTLIFLSHIQAPLLPRETTHAHYLKPHPKVLEKITKFSSPSVLFQDSPSPPPFGSHPKKAPPRPNVSALSVSALPSSSSKQHTPMKYTNLQDALNASTVHNAEDDYIGAFIDKSRPVVRRKQKQSPFDGVYLPRKKAKLDPSTVAAPSAGNSSVSVVVSQKPTTTKISYIPGDIMVTDKTLEDGDDYVRLFVGRDVDFISGAGWMKNAHESTIPNSSSKQKKRDHRMLLVKNSNTRHIGAKNHGQVEVQNLGTKRGLPPGLNSCSAGLINWKGKDRMSSFSKRNSGWVERMFASIFAPETVAGYWIVQNSDEEFSGDETDDEDDLPYLDLSEVHRVRASSSYPSANTGKSAMPLTNPNPKSKTQPHGSPQRALSSFFGGPPESSSPKNIKFRKKPSSSRTPNAVAQYVDSRSSYESLSTSSGSYLSVSVPTSFSLPISRSSSSLTAQSLRKSYSQPECPSLPAKGQQFSIQPDAKLLNLPGLSNKALGKRKAFDDGVKPHVKRGRPAKPRPSTVLANSSMSQYHGHVSHTHHDAYHAQNLYEARGNHLILDSVGQHELFSRTSAVPASGPSTILGAPQITDNLVKIPSSEGNQDGHIYRFSPHAHVQTSTQSNAHIPGSTFPTPIASVGNPFFGDGAESGVETEAIIGQKGHDEPDTHCDDLKWAAEKILVLLQNDPQQVKDVIEMLQLQRPSQTANTGSTLPQPRSHRSFDGFLNMQHDVEIGQASRNFSVQGDHREVDVGEWLVPSLGIRRIPEAGDQVNTEIEPGLYPGPSRSSRAGTEITTPDHPAVQFGQHKHTSVPPDADSNATINPSILFSVEDEHVLSDGLAMLDSSERVYYSGDPLPPRGKKRMISVQPKAQKRRNTDIRPSATSPVPQPPPPLLQSNALSLVLDYASNSDSEEKDDLHEDSLDFDVHFHTSVSALSATPATLASPSTVSSSLQESKATINYGVDAISIGSGSGLQTGSERSLTSRLTIHSPKLRLSDLAALEIPRPANLSQKAKGREKEKKKKQVPVNRRNWPLGSSEYFCHQCRRRSSRLHMACAFNDCNLKYCMRCITFRYADLLAFDADRKDFSCFRCTNNCRCDACCRKRGDIYIPLRTKQVQPASGNESAELMAVTQRRQRRNANRKQMDLELKTKEFEDGTRSESAGPSGENTIAGRRERRDKAKGKAKQELETITSSEMDTECEKETVEGAALTKSSWPEGSLEYYCHQCRSKSFRLYMECASEGCNAKYCIRCVTSRYANIISFDSSCDDFVCFRCKDTCICDICCRKRGETYISFRRPPARPTTFKPAHLRSRQSEERPYPKLAPITVDTQVSHPVVYWGAVYNWTGEVIASAYVASVENDGVIFARPLQKRRVFIGDVQPDWEMGSNSRIRYLGESRENVDHDTSLGPLPTTRKRKIFYVGQPPPPSTVISASPSGPIASSMGNSAAYPVDVDEVESQAESMSIDDIADQSVIANGLGASFSETRDSEREEVLASGNLRTFMGVRPFSHSSERDAYKSHSTHNLEGRFRSPETRRMKIDVNGDMDVQPSSAVAEGEIGKPLSACDFEAPFDNPADVQGMYDVYGDSKTDMVIQISATADEDEGEAAIGTDLKSGAVTMNCGETKAESLDPQMDYDTTENFHVPYDNISPTSATEFDITVHVEDPELSVVQDHASHTDSHSDALVNDEAISEDQEYSTHNSSITTDTHPIFETPFENHEFPLDIGSPLTDLDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJY1</accession>
    <name>A0ABQ8VJY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rad1/Rec1/Rad17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_833195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003021">
        <property type="entry name" value="Rad1_Rec1_Rad17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02144">
        <property type="entry name" value="Rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01245">
        <property type="entry name" value="RAD1REC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="119"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="40879" checksum="352F9483D3DDC78E" modified="2025-10-08" version="1">MSQAGDIPVLKASVHDVRYLSALLRGVNFANRATVTVTEKGLVIVVEESRTLLGTAYIFSDAFDEFIYHAEAEAPEAQGSQRQQQTVNEELFSAFEIPLNIFLELLNIFGTAGGPATSKPGRFKAWRKPGDESEEHESDGGEGGGAQDEGSSNKKAKTGQFFGGGSERKTGMRLTYIGPGYPLTLIVAEDASGLTTTCEIATFDAEPHLELPFDSDQMMLKIILKSSWLRDALSELDPSCDKLTFIGNPSDVPDAGAHTARQRQRARMQAQPNFRIEATGTFGNTEMDYPNDRDVLESFECEAPVRFSYRFSHIARTIRALQTSVKTSLRIDNEGLLSLQFLMPSSTPRMNPVEVTSNFIEFRCLALEEDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL49</accession>
    <name>A0ABQ8VL49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Voltage-dependent anion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_760613</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09317">
        <property type="entry name" value="TDT_Mae1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030185">
        <property type="entry name" value="Mae1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162:SF0">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="43557" checksum="7DE7715E7890793E" modified="2025-10-08" version="1">MSEKQRVGTLARRIHGWSWQAFPIGMGTGAVYVTLSGLKEHSPTLTTVETIFYFLNISLFILNTTTLMTQAILFPRQAWRLINDPVKGIFVPLVVLSFATIIIGTINYAVPPGYVSPGFIYVLFWIYVAFACLTCLPMLMIWFNQPHDLATFTPAYAFLIFPMMLVGVVAFNVLKVMNPADTRAVGVLVLGYFFQGIGFFMTFFYLCIYIIRIMSTGFLDGHQANGAFVACGPPGFTALALLNLGDHARKILAAHGLITPAAGDIWYASSVLSALMLYGLAVFLFVFGVLPYWFKVHKHLKEILGCWALTFPNVGWISTTRVLGDVLHIPGLYDVHLVMTILMCLTWAVLFILTAAAFWKGLIFYSQDDDVLKDLRQDNDSTLSYSTASTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLD3</accession>
    <name>A0ABQ8VLD3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_233873</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="22522" checksum="7D1A03EFA709F7FC" modified="2025-10-08" version="1">MKRPRYDQSAPGGSSYPPVNRAASYSTPSPVAARYQPSGLTMPASSPVIRTERAENRYSGAPSLSYGPSPYSYAPPPQQHAQSSSYYAASSGSSRPPAVEDSRVEQRSLGYTPVATAGQGSRPEEGPSKANKYECRYCGKGFLRPSALKIHIISHTGDKDFVCPEENCGRRFGVRSNMLRHIRLVHQNNHSHSSGEELSKDDEWSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLQ7</accession>
    <name>A0ABQ8VLQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="45247" checksum="CA75862F4D566D34" modified="2025-10-08" version="1">MPPSSTFPPEIYDRIIDEISPPSKDAFSTCSLVERSWVPRSRTHMFRRIDFRIPSKNQADLLTSIGRTTEFQRNVASNTDVASYARNLVLTLTSSGNIASEIPQASKLHNLISLTLSCSNIIIYAVNDAIFTKLLSFIRHNQKLEHISVRSLVIYPPAFEVLMACAAIRAPVLQSLHLQSIWGPDWITDAWNRRKLVPARPSQSCRQASYLTGLYISHCENGVITTFLGSFDLRNLHRIALMNLDWGSCMTMTDATLNSTLIHFTLDLSDHRHGVGEEQIFNRLVNIPTVQLVLKRFSDAPMVLHGLQRTLFQGKPCIQKLHLQFRQYPFPSDTMVDTALRELHLTLPSICISIGFEVQEGIRPCATTTNIGALFGWMGQTGRLQFEALDDWWVHEATKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMA8</accession>
    <name>A0ABQ8VMA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_208531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="31121" checksum="C08AC44FE6D7BF85" modified="2025-10-08" version="1">MPKRRCDEPTCIYPFAGTTKANHRAEYHSGGHAFVYLGSLVRVHRRSDGKIPCPCGHESHARYSFKKLTALNKQLPHPRPEASEWSDHPLDTTANPLPPPPSSPPIPASPHIEHAASSSSHEPQCSSQQHSPGQDTLSPPTNSSGSALETRHGSDLAQGGFEGVHHVNDDVEGLDLGSRAGTEVHEDVEMRDGVGELVIDGDSTGDEGLSSEGEPSDEQAQQTDDSMAIDYVSRQDVINSLARFNTLVEPAYHLVVCTECAIPVRMDDMYTTRRRNTSNPSTFLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMP9</accession>
    <name>A0ABQ8VMP9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_759278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045594606" evidence="1">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="19753" checksum="86C7AD8B66ABA73B" modified="2025-10-08" version="1">MYQFRTTIFFVLLFWAVTAFAVPTFEGQYSIGSLIPGLSSLQALREGHSRKSAPRHLNVHAIGNLTITSGAVGTPLFYIHRSRLWQYVNETSIHAVNVVNGTEDAPGTNQIPLQMMLDEQPGGINGGVWKWQGTMLIYQLGSKNNSGVYYDCMLPKGGRGLLTFLQGYVFRARSRAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN07</accession>
    <name>A0ABQ8VN07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_821083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18110" checksum="A40C3F6B242FE1AF" modified="2025-10-08" version="1">MKIEWASDFHRDGSRRSHPIASTMHGWLAKMRGTLVGNEKLRSEGMREMRQAKANRKHRKQNKSQGRSSARRGGFSLFGSGRKPAPQHRGSRNVTRGGHGGGGESRPALRQHSSSSHRLVGQTSRRGSGVQSRGSRTPTRPGPSRRTTTTSQHRGTTPRRSSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ36</accession>
    <name>A0ABQ8VQ36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_864695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="303" mass="30862" checksum="B9AC028F8206E8A0" modified="2025-10-08" version="1">MVPDSLFAGSIIQVGAPSVLSPSCVTSSSSSSDPPMGNTQTSPAHSDGDGLLDMLVPPSSSDPPIGDTQMSPAHSDGTILASTSNSNVPTGGAPTGPARAPTSSLKAPTGGVPTGPALLAAMLAKEPALLSSLDADHPDIFVDGMSTDVAAEITTGANAKDKAAGSQRKQAQKKDTTAAKSKKGTKVISKPPVEENANEKSSNSGSVKIVVGESGKIKIVFSSGESAKGDMSNLGDGGGAMKENTLPSTMERSARPQRSHKEAPSREPITIKEINIRRMATKRSVHEAGLNVDSDSLKKAKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQP0</accession>
    <name>A0ABQ8VQP0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_756711</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="192"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="451" mass="50491" checksum="6DC0CB04FD8D2C0C" modified="2025-10-08" version="1">MEGRLEQAAALGQKDKGPAFISLINEIISRSDQSTVARDIPTLVGFVVNQESVGLVVGRQVLSELVRIVGDGTISDPEVRKRVVQETIETTQPKIVSYEEQVSNLRFQLADIYENEEEWSDAARVLMGIQLDSNQRSLPDGEKMRVYVRIVRLLLEEEDSVQAESYFNRAQLLVHSTTDKETLLQFKLCQARISDYSRKFLEAASRYHELSFVADIDEEERRHMLMAAVTAAVLAPAGPNRSRVLASLYRDERTTELPTYNILSKMFLDHILRPTEIKEFEGTLKPHQLAKIAISSNDRVATSTNDEEIDTRSDPPISTRTAPATVLDRAVMEHNLLASSKIYHNISFRGLGALLDLTPGAAENMARKMIEQGRLRGTIDQVDKLIWFEGNHEEDDAQGKAGGLGEVEEAEDTGAPFTKRWDAQIRITAANVESIVQHLTERGLVRVPVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQS9</accession>
    <name>A0ABQ8VQS9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_893929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="6"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="36663" checksum="2F9A2C8540684154" modified="2025-10-08" version="1">MPKGHIDVHHHFFPTELAKIKEINFAEIGFQSPKENFPWTPEVSLKFMDQTGIDTAILSLPALGSGTVSEENRALARERNMQMARFRDERPTRFGFFATMPFLQDVQGALIEIKYALDVLQADGVAISSSYGEGSEAKYIGDKLYEPFWAELHSRKAVVFLHGNQTPSSTPYPDTTLGLPIVEVPNETFKAASHLVVTGTKRKYPDIKIILSHMGGSTPFLSVRVARLSHYMGCPLSPEEILEDFKSFYFDTALSAHETTLTAIQSFITPDHLLFGTDFPAVNREITSWYTKHLEDFFADSKDKYEDIAYRNALRLFPRLRTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQT3</accession>
    <name>A0ABQ8VQT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_978838</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="64"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="571" mass="61854" checksum="7D80F9934CDDD939" modified="2025-10-08" version="1">MASTASIITIRQRRPLSQVQADEGVNPYVSRRQSTISCHNAVHPTEYHASRLPKIERTPIPKLQVSMVLLIQLSEPIAATVIYPFVNQFVASTGITQGDEKKTGYYAGVIESVFFLAECLTVLMWGMASDRFGRRPILLIGPLGLFFGAIGFGLSTSYSQLVLFRSIQGAFNGNIGVSKTVLAEASRPNSLADASNLADVFAFNPMMWCLGGTIGPFLGGTLSDPANQWPNTLGRISLLREYPFFLPLAVSGCLSLLFVTIAFFGLKETRSFQISNPQTSQSQSQDRKHFKRRLSSRSIDGLAQSAGSGFYYGSVAAPTACSFISTATASSFVEPTFSALGTGEDDDFPQQPPTLSSLMIPQVLFPILSYSLLATIETSISVLIPITYTTSVASGGLGLTSFQLGSILGSWGILNILFPTFGIPRMIRYFGPWKVQLMGMMCPLLILSSLITLNMLAKRPVGGNDDLLFWVVVAIQFGSYTLMNMGFATAQMFVINGAPNQAALGTTNGLLQTAKTLSKTIAPVFAMSLFSISKEYNVLNGYLVYFFFIVVTLLGITTVSKLPKELLNLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRI0</accession>
    <name>A0ABQ8VRI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_755729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02340">
        <property type="entry name" value="ZZ_NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052260">
        <property type="entry name" value="Autophagy_Rcpt_SigReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15090">
        <property type="entry name" value="SEQUESTOSOME 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15090:SF0">
        <property type="entry name" value="SEQUESTOSOME-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="7">
        <location>
            <begin position="644"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="7">
        <location>
            <begin position="753"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="6">
        <location>
            <begin position="849"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="908" mass="100420" checksum="AEC86E6E371FE153" modified="2025-10-08" version="1">MNQHNPDKKLVVRCTFNKSQKKITFQSAQRCTFDNLREKIVQCFSLSASSFEIWYKDDDGETLKIWTDDQLTEAIIYFADAADDAHTSSASSIFSGRSFGSRKITLHVQIEVEYEGPSLSDTGSIASLEEYGSGNGDVGEWSSAFSARDLDDDSATVSSRDNGRLSTRSFVRNRVSSPLHERASQLSGESSWDAFSGSTGRARSVSRQNQDPFADSNGQSPNGILERLRLENDAASTDYDPLASDQRGTEWLKEQNERAKRSLGVLPASSASDESSFSLLEQEDQVGPLSLQRAPTGRYYYEYDSEASQSQMTGPEDRGFEIDPSIDGGINGKPRPTSRQWAWLTAQRDAAALRPPPHTHRSDPSLETIVPAEILQNLDPPRGENLTCCSGCGRFLDYVKYVCYTCRDKEPGSHISSPSSNKSKSRDYPPFTYPPTPLQTNIYTSPLSLNFSSSSNTFVGSPSKRRPLPPQPSVSTSFATLVPPTSPRTATGYELCYECIEEVGHMHAIEAMNEPGSSPTTSNFSSSSPKDAAVQWRRAPPKQKGQLRHAYVEKIWGHNGWDDIVHTEKETEICSACSAKSSPQQMMYICVSCERYQLCRACYSQVHDLHPVHTFLVLRGRPPSDSDVTYPKSSNDFEEPSNVHRGVECVNCRLEIVGARFHCVECESVDICSNCDSNGLPGNIDSADGGHHSSHLLIKIPIPLSNSGVQSVSRKARALWTKNPANVNRVEQATSEISSYARTVIEMGNKPENHEITCDACQKPIIGVRYQCANCPAPQSEYNLCSSCEDASYTVHNPMHAFFKLRRPVDLPIKSSDPMIPQLYKDPAGPSSAVYDIGNPTGYLLSIIHPKVRCDCCYTEIQGAWFHCANCGKDLCSTCEKIDTHNDSHVFLVLKALVSLSHMSVRHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRL3</accession>
    <name>A0ABQ8VRL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_864193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="31037" checksum="28AF9A6C9384A67F" modified="2025-10-08" version="1">MAEHLDFDPAKIPAPDFAGETYAFMRTALIADANTPEVTTNELAIQRLKEQWEAHIGGLKTQYQAQLQEAATLREQNRQEATAAKELAKAERQEKEKELLKEAEKKHLPIYSFQKGLGVDSIPLQLHPYAKKMMTARKYVPLWYFLPDAATEAKERTKESLDTNHLQFVVEDDGPVAGSTISLVGSHSVRASPNTIPDSQLSWPQVMRAKSAFLNALQLGTWPDTFIAMFAGFYSNMDMHRELQEQDGDQVMAHYYAEMRLAWYDAMERKRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRN2</accession>
    <name>A0ABQ8VRN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_815750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="108" mass="12496" checksum="339A5D1E0E96829F" modified="2025-10-08" version="1">MPSSKKSHYKKSIGQTSSGEELWLVDQVLDDRRNEAGIVQYLIQWSGWPKSYNSWEPAEYLSTCRGPLQVYHERKRIKLMKGDSSISSPSKVSIIEIICPHYVFFCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSE3</accession>
    <name>A0ABQ8VSE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP11 protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_931439</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="318" mass="35449" checksum="A9B9C2EEEB0B0084" modified="2025-10-08" version="1">MCQFSVPTNLRKIRYNLRQGVSVSKLKENAKKLQEEEKKRFREANEEAIRARKAVAVEPSSVSRPEVAATPRKDSSPVKPLGSILNLPRILSVNASQVSALWTAYHASRSEGTGRGYLCASIPLEAYERMAAVAAKYPTFVLPVPRPDPEAIQGNANTTETPYEFQFMQWAFHESPPIPSAAEPDPFVPSTNTYQAADGSSNPPTSSILFTPLQEFKMRNSFATPYLVLTHYTDLARTHGIVLLRGEITPGSGNDGRYLLSQEDAQILSMGVQKFYLWSDSKGVQQKDGSTGESILRTFHEKPSEFNWQEMLKYSTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSR8</accession>
    <name>A0ABQ8VSR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sister chromatid cohesion protein Dcc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_908479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="44082" checksum="3C656B5CFE908CEF" modified="2025-10-08" version="1">MDHNLRFSVSSLTEQGSYKLMELPPELCKVMEESLSEGGDSNSSSFCIKGQPGEDAVLCTQDKTYTIRSVSLSNSILVVTSPADSDISFDGGDNGLPNIVIRDQLSQILELTQTVPKLHKLNTLLKGKEYGEDEEDNEDGMNVELAIDHSQNMEHFTYTDARAMIQASETELKSGLRQRRILQINETLRPISSIYLTKIIQYILNTLAALMLNHESVPVEKLCTTLADEHDVPRIVSVQVMGWFGDINEIDGKWKMDVNSVVKEAGLGILKDAKDRSYDKDDLISTWKNLVGDKFNSSVSLDLLAGNYLIAPAAPYSDHQVVKYFPISSLPIDPAQRFSDLFLTRSKWKNEDIVPFLSDIAVNSKERDKLLLKYARATTDAEGIWYTSRAQYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSS9</accession>
    <name>A0ABQ8VSS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_909046</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="234"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="554"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="622"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="656"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="678"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="757" mass="84276" checksum="1F68A28AE45B76ED" modified="2025-10-08" version="1">MTIKVELVPLPILEKPPRTDFGSTEKSYPPSDKDDAQVADGESEAALDEVIQDAEEVALKVISLQDDPTASAVTVRSVFLGMGLSAFSSVLGTIYTFKPQNATVSQLFCLIIAYVLGTAMASIPSHGYWRILNPGPFNIKEHTAIVIMASTAANVSLAMEVIAAMNLFYDIRLNTAVAIFQIFATQMLGYGFAGILRTLLVYPTYAFYPSYISVVNLLQSLHFSGALNAKRRKFFWMVFAAIFFWEWIPQYPFPLLTAISIICLADNGRHAFVRNLFGAGSSNEGIGLFSFSLSWTLITQGFPLVWPLQTQVNSFIGMALSYIILTSCYYSNVFNGRDLIWMSTSLFGTNGSTYDQDAVITSDYRLNETALKTVGLPRYTTTYAIAQLSYNLSLGAAVTTMLLWHWPKLSKAFGKMQILKSGPADVNDPHYQEMLKYPEVPQWAYGALLLASLAVCIGTSYAAPTVLIPAWSVIFFTVFAFIMSVILGFITATTGFNISIQYAVQIIAAFLHPGQPIPVMYANLYGNATAFQTLYLLQDLKLGQYTKIPPRVTFAAQMLGSIIGSICNYTMMITIVNANREVLKDPTGTRIWSGWIIQSTNSASVAMGALGKELFTFGKPSGYWIIPFAMFIGIFIPFPFWIVYKYTRQGSWINRTMKYLNFPIILLYMGWLPFSVNGQWWSCVIIGFASQWWIRTRRPRWFVKYNYLLSAALDGGSQIILFILSFAVFGAGGNSIAFPFWWGNPENLSVDRCMLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT03</accession>
    <name>A0ABQ8VT03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_822026</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23810">
        <property type="entry name" value="UBCc_BIRC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="619"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="43"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="468"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="856" mass="95288" checksum="118BE4DAC10DB9ED" modified="2025-10-08" version="1">MDREVQQLVEMGATAGQARAALNKYKDVMQAAEKFFEGEFENVAGDDSGRAHQAHSSATSRDPDVEMDQEDDDGELEDDEGSDAYIDYDSDDDGGMPGDSGAPKVNDPYAGIFFSKDRREEVIEIEEQSVFVSVPEINEKVEVMTQGRWMAGCAEGGEQSFLFSLYSQLGQSQLSDLDGVCPCPSGCGQTVKRQQSDFFAIYPKFSTYIQHLQSKVPQRCPKCQTEFCFACGEKISQDASDPLWHCSNLQGVILGVGLFMIERLFEQQKEESEIKETTERETKRRKTRDIDDDKIDTGSGKTKGGVGYAGELKEDSSGQAEAQANQFAKDSKIRALLAEVRVYLPSLQRPGGARPSDYLPHPSSLTHLRRRFNLITSELLRNDSLADMSDRHGLYFELLEWLETISSHESLCSMMPMPIMRSVSQQTVVKKTNTSTIRERKIIYEGSASPRELLEAISLQAQAALKGLESSKPPEDPSPEPNEEQKRKTVVADKGKSKGDALAEGNFDETAKLYGFCNRLLATTVQIDRSLRELKGDDFVTRMHESLPKAYTSASDTIYVDAGDTEEDAKEAYVKWATSSRFEYCDLTIPTTDNSDETLNYKHYFNNEIRMLANASIPKRSVAIAKELAILTTNLPVAWDSSIFLKVDDTRVDVIKCLITGPEGTPYHNGCYLFDVFLGANYNQSPPGVKYMTTNGGKYRFNPNLYADGKVCLSLLGTWSGPGWVPFKSTLLQVLLSIQSMILCEEPYLNEPGWASNAGTPQSKAYSANVRRMVVKTAMLDALQNPPEPFEDVIRTHFRLKARSLKKQLGNWLREDDHRALASDGAEYSSAGRNSSTSINDFKADIDTLKSLLNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT71</accession>
    <name>A0ABQ8VT71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PARP catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_101680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31681">
        <property type="entry name" value="C2H2-LIKE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31681:SF3">
        <property type="entry name" value="OS04G0690100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045985913" description="PARP catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="3">
        <location>
            <begin position="349"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="470" mass="49184" checksum="0C420124ABF6180A" modified="2025-10-08" version="1">MAASVASHIPLALSLLHTVATQYPGLTKSQPTTNVNTAPSVPSVPAPAASLSVALPGSGSGAGNGSGTGTAGQTNGQAFGTTGTTSGAGTRVGAPLATPPTSSNNSSTCEHCRLKPKYHDGVKTHSYCSKSCATNAKLANGNQKAPRGHQHGSTTPSGNCDFCHNRPKFPGHPFCSKACANNASSSLHTGGNPKGTCQAPGCSKPTHVNKDGTCGDYCSLSHKTLGETLCIMCLKAAKQTNSHFCSKACADNAEMKGPMILEVPAGHVTFKDVSDQFKASWRHVGAKCPPVKRIYKIVSPQSSLASYNAYKASVEARGQFSAAGRSAGNENRRWHGTKRECHLGDKGYTQFCGSQTCSLCCIVKTSFDLSLFGKKTGWGRFGKGIYTSSTSSKSNDYSTNECRSSLKAILLNKVIVGKGCKLTQDNVSLTTPPQGYDSVLAEKGGSLNYDELVVYTNDAIRPSFLVMYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTC6</accession>
    <name>A0ABQ8VTC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_915359</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="4">
        <location>
            <begin position="110"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="321" mass="35691" checksum="3296387F4FFE9173" modified="2025-10-08" version="1">MSDTIPQYHTPILGMTSRPRVPQPVEYGDPTSNNFWVEYPHGLVDLSRSTHIKDLKISAEKQLDIDTTKEPGAQNNLLSGSNTITPTLLPGQLDVQVTGERTVRLDTEKTAVVIIDMQNFFLHKDIRDHPKGLACVDPLMRVVPFFREKNIKILWVNWGLTAAELSTIPPSLVRGFAKHGSPRGGGFGSELPGDFGKLLMRAERNSELYGPLQGLYENGRDKGTDFWIHKNRISGLWDQTLLENFLKENGLKTLFFAGVNADQCVLGTLIDAYFRGYDCILLEDATATTSPDGAFEAVIYNAANSYGFVTNTKEVLNCKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU42</accession>
    <name>A0ABQ8VU42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tail specific protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_819265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045042434" description="Tail specific protease domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="688" mass="76183" checksum="C6D6385D5903E9EE" modified="2025-10-08" version="1">MIISIVLSLFSLAVAKITPVPLDYCAAIAGKQWVSPLEVRSCMHSFPVNQDIKENIIEVLNKTIAMHTSVNYQISAPKPFDKDVHEDLHKDLARIRQQKYQSEFEFHLDIFHTFRRLNDGHCVVINLCYDSLYISYLPTPLVLLTAADSRQSVHIAPEAFAVASAEFGEEIEFWQNALPGKLQGQLETLNGAEVLAINDQDPFVAVNSNALITGGYQSFGTRQNSFFSSYYRGADGWLYQMGNFAQQVHPLTDVVKLAIRRVNSTSIDIVTLPYRSRFGRGSKNFTNSASYRANNCIATNETNGVDMYAVSHSTTQEHSEDPLPIGYFQQQPPIPRKEARRHPMNVLVDALPLSNIDLPEIMQPSKPALNESYSVAQFYMLDDNVTGVLALGSFSAANFSAFQHSLLDGLVELKSLGATQLLVDVTNNGGGYICIAHWLHRIIIGSKSTTEPQAGLDTATRAGTLAQLIVQKIVEDVMDPDALLYYNPTQWTNASNIPFSADIEWLKPLQELMINGHEDAFSQRLGQECQPFGVEPPRKGFFKAKDVVIISNGRCASSCSLFSITMSKLEGVRTVVVGGKQGTTQQYCGVVGGQSTDFSTIDTEIKSVHLKNHTLAPPDLSANIIEGITWRLAYGIDDPTEPEEWQDHPADINFPLTMETVNRPVAIWKAVSKEVFISSPPPLLVQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUI5</accession>
    <name>A0ABQ8VUI5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_893565</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="441"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="610"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="682"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="757"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="823" mass="92863" checksum="A71C8F1BD0A2C73E" modified="2025-10-08" version="1">MEDTKAYNSSTEEIISLPTRTIRARRAPDVPVDVDADAEFVKEHLNDPYMDLSRPYKSTESMELSDKKIQQLQYAPSELDAESNVDTFDRYSTSRAESRNSTAIEFDDESPYPEVRAAVSSTDDPEMLVNTFRMWFLGIVFAILVSGINQFFSARYPSVYISGIVVQLIVLPCGKLMERILPTYRFNTFGLRWSLNPGPFTIKEHVCITIMANVVVGGAYATDIIATQKIFYNQAIPYGYQILLCIGSQVLGFSLGGLLRQFVVWPSSMIWPGALVNSALFNTLHKSYGKRDRGHMTRERFFLYAFLGSFAYYWLPGYLFTALSVFNWVCWIAPNNIPVNALFGTNTGLGMGVFTFDWSMIAYIGSPLVTPWWSELNTIVSLVIQFFILVPILYFTNAFNTAYLPISAPVAFDRTGAEYDVSQVVTNGQFDNDKYLSYSPVFIPATLCIAYASSFAAFSAVFVHTFLWFRRDIARRFRSTLKDERDVHSRLMQAYKEVPWYWYTAVGVVAMVFFLISVHLVPTNFPIWAAVFAFAISSLLSLPMAMLQAITNQQVGNIQVFYELIGGYVLPERPVAVVLFKGLTYVTTSQAIAFSGDMKLGHYMKVPPRLMFTVQTVAVVVACFTVTLVQNWMFANIEDYCSPDQKDGFICPSTNTFATSSLIWGGVGPTRMFNIGRPYNPLLFFYLIGAVLPIPFYMLARRFPLSFYRYINIPVFFGGVGALPPASGINYTSWAAVGFIFNYCMRRFHFRWWMRYNYILSAALDGGVAISLIVIFFAVQLPRGGFTLNWWGNTVWTNTADAMGLPFKLPDGPNGTFGPSTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUZ6</accession>
    <name>A0ABQ8VUZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_531474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046577273" evidence="1">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="110" mass="11632" checksum="732974FDAA9DE092" modified="2025-10-08" version="1">MLFLLAWLPFFLYSVVQTVSSAGVIGPASSGPTMTVSEKITATWSLDARDSTLSQGFSMVLVNDAADEAIEWSTTVNPSGKSIGTIHPIPTATGYAPKRCSVIIPLCQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV39</accession>
    <name>A0ABQ8VV39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_978390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="23911" checksum="7B992A9C6338BB5C" modified="2025-10-08" version="1">MNSSVEHLSPTTSSARFSLPSKSTAGPKPNIYERNLNKTRVAEVSAASLSFLFSEVVQYTQKRVSGVNDLERRLNTLGYRVGARVLELTAYRAESSLKAPKREIRLLPALMAIHTQIWRAVYGRPADAIEKSVENVDEYMIIDNDPLIERHISVPRDLSGLSCSSFSAGIVEAVLDGLGFPARVTAHHTPTSTHPTRTTILIKLEKSVLDREDVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW66</accession>
    <name>A0ABQ8VW66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_814136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="25953" checksum="898DA57EEABA0419" modified="2025-10-08" version="1">MTKVIHFTRHAQAEHNVDEDYFIPDAPLTPLGRRQAEELYSQSTELQQSADLLVTSPLKRTLQTTIIGYRGLRARLESQNSPKPIVVLSRLQEVNDFPCDTGSSRYELEQIDEFAGIDFESLEDDWNSKQGDFSPSTGAVKARARWVRRWLRDRPEQNIVVVAHGDILRQITKSSFHKPWANVEVRKFTFKHDSDDEANLVALPAETEARAGGEEPTSSEFKFNHWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWB3</accession>
    <name>A0ABQ8VWB3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_434070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045946884" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="16347" checksum="D37C809D2A9E533B" modified="2025-10-08" version="1">MIRSIFSVVVVALGALNALAVPVERRESVLSTCNTARLGVISSLNSSSRSIEALLNSSNDSAVISASNQALSGLHTSQGGVATIVKGVLAGVTPDDTGVPAIASGLATIAQALSSINSTNDSNVQSQLATILTQVNGIKTNGDNAIAECAKLSQSCHRHCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWH4</accession>
    <name>A0ABQ8VWH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_862870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37487">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37487:SF3">
        <property type="entry name" value="CLEAVAGE_POLYADENYLATION SPECIFICITY FACTOR A SUBUNIT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045317492" evidence="2">
        <location>
            <begin position="19"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="19841" checksum="F4AF1ED7E7E4808E" modified="2025-10-08" version="1">MKAVLFASAVALISGAYAQDFTINTPISDESLKIFYSGSLTECEPVLLQWTGGTPPYFLSVYNSGSPSTNAETLTTTNSTSFTWTVNIASGQSIGFNIVDNTGAEKQSAAVAIQAGSSTSCVGQSVSGSAGATTSAATTGSGSASTTGSGSSSTTAKSTGSSSGSASSTSAAGSSTTSSSSNGASSQAAQLGAAGFIGAAIAALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWP8</accession>
    <name>A0ABQ8VWP8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase, V0 complex, subunit E1/e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_750931</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="68" mass="7368" checksum="92821E5C06A83AAB" modified="2025-10-08" version="1">MPSVLPILFVLVIALGLMACAALFTPKGPQQVLIRTSLMLALAACYLMWMVTYLAQLHPLIGTPARTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWX2</accession>
    <name>A0ABQ8VWX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Skg3/CAF120-like PH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_359291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058155">
        <property type="entry name" value="Skg3/CAF120-like_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25381">
        <property type="entry name" value="PH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Skg3/CAF120-like PH-like" evidence="2">
        <location>
            <begin position="100"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="965"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1179"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1693"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="601"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="715"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="818"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="893"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="976"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1214"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1697"/>
            <end position="1722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1735"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1792"/>
            <end position="1808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1809"/>
            <end position="1823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1829"/>
            <end position="1843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1843" mass="192487" checksum="995E839EBA4C4436" modified="2025-10-08" version="1">MTVSAGSEGVAGMNGPDELGRISSNNPNNLNNPNNPNSPNSNSNANNTNANASITSPPSSAGSTITGFTKKRMSALFSRDSSSQGGDQHHHGRPSNHRNNSNANEPPMVSMYTSPKPKDRKKPILTLPIVSQAFAVYPERPELISRSTLFKVEATFGTEDGAGSMRGREGWVLIMPQLEGGLSQAAEMLKWVIAFHDTFKLYGRPQAWSWDPRDPASLMFAYPVGPGKDLLFLDREHAESLDPRDDRTSSIRSRLIGILKERMELGGPPGSAGSAGSGAPITPPGASTLGAGPSGAGDRTAQQSSSNNSQARPGSSGNSGPLSLPQLPPLSFDSSSAADDVREERALLTPITERSSVYTASVMRSGTIGTIGSGFGPNGSTGGRNSGYGFQGPSPVLEESDREGTGSVSPKVPEKDFVGMRGMSFSSVGSGGGGRKSVDVPPNVNTTSSTTPASPPPPTRSISPTQGNASGGGTGSPASGMLPHSSFESFSNAVNTALPKSKPMSPSLSPSLSPSSSTMSPPANFPNPQNPATANPSNSSSSSSSDRPMTPPPPIGGGGANFGLGFRSHSPALSHKSHKSHLSQSGVSILTSPFSVADHAPGTPSTPVTPGSLSTPATPSASSGPALSNSNPPGGPSPTKNAGFGDRASILTSPYSPMNSPTTSVAPLGNPSSHPSYTPSHGDSDAGLYYMDNKDNNNSTNVADYHRHHHRSTLQQQQQYSQQQHAGDNTGNSAGIRRIPTTIQETESADASDGDIRDIRELRDFHDDNLQRHGGSNSRDEQGNGTVNAKSMLGFRTAGDNRGDYNGDITSQPGSKSSSEDLRRRYEAANSHQSQSQTVITGMQASPVARKGTPMAFMGSSPVAPSIGSPGLENQMNNLATPRSIIGSPTFGSRPLSSSPSLNSPSFGSPLASPPNSSSSAGSIAANRVVLGAERGLGRKPSGARAPQRQQLGFSMSAGHVALPPVGVPEGYDDPAAANSNTASSQSRQTQFSSSSSLPPSHHVPGVSEVSEEQDELQEQEDQERLETPEEGSSLEDNSVDYQQYQQQREERRQQQLQQTQIPPRHQAYRQQSSTTTATTASSYSAYSTDNNTYNTYSNAGFTAGNTSENNTNDNNVININNAKHAMASQSSSQLHAEDDDVFAVLSYLDVNDPGEDDASGTTNAAKKVEPLSVHRSFANNANNGEEGLPTSNSNLSSPTSSSSFQNTSNVSNPQTTNIPGIPSQGSGPQYKSSFAPSKSAAERKAKAQAAQAAQAAAIHRPGGRAATAPGGFGGGKGGGTRKMRAVPNTNKPGSWSSEEEEEEEEEEEDDDDEGDVDSDEAPKVRGKTGSKAGSRENEDGQGQFSQLRPPRTLPQIPGRMGEGDQYPAQSGPPRSNYFDDQQLQPPPQLTQQMRSQSQYGLSPPISTPGMGAPRQSMWSQVLDPNHNQGSVPENPHSAPHSFANPIAPTPLPSNTNNPAIGRGGNDLFVQLEPPSTHLTKAFTPQGLLSAGLSDRQDRSAKRQEEMARESGASLINVPNKPPPPQTGLLGAITGYERERKRDGGVGAALTERERERRMVEERQRRWDEQQRMQMEGGMPGMGQMPMGQMGMGGPMSMYGGFPGMNPMMSMYGMNPMMMGGMNPMMTGGMPGGGMMPMNPMMTGGQMGGGLSPMMTGGMNPMMMGGMNPQHMFAAQQAAQAYQQAMMAFSVAGSQAGDDNNPSKNPAATPAAGSSPNLNPMMSGNFDPRMSMMSMGGGMGQGMPPGMGQGMGMMGQPTPTSQFDPRFSPSNTPPTNSPTNPESTGPFPPGGPGAGLGQGLGAGLGQRIGGRASNSSSPVRKSSPLARPDNSNNGDGAASKGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX14</accession>
    <name>A0ABQ8VX14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF1">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="20376" checksum="C4981FBB74026F0D" modified="2025-10-08" version="1">MSSTEEKFEIAKKQKETGDQAFKDGKAKEALTSYHGALMYAQGLDKNAFKSMGMTEPAEAGKEKTEVDELLEKIYNNMSACYMKIGNWKRTQETAEKVLSKNETNYKAMYRKAKALAEQGYLERAYKLFSDLITKNPSEATLYEQELARYKAIDAQREKANNAKLKGFLNKAEKKASAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX19</accession>
    <name>A0ABQ8VX19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Adenine nucleotide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_809473</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF1">
        <property type="entry name" value="MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="10"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="116"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="234"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="353" mass="38419" checksum="94940F8EED9AB13B" modified="2025-10-08" version="1">MSSKTKPQTLSPLAAALAGALGACFSTAVVYPLDVAKTRIQALPKSKGKDDSSMFALIIRIFRKEGLLALYSGFGATMLNTFSMQYAYFFFYSFVRNSYISRITRKLPKGSKAPALSTAAELLLGAAAGALAQIFTIPVSVIATRQQVGRVTKPSSITLPSNASEVFELNAQSDDSFMAVAREIVEEEGVAGLWLGIKPGLVLTVNPAITYGMYERVKSLLLLAKAKGGSSDKMTALQSFVVGSLSKTLATIVTYPYIMAKVRIQARSADIHDDDPKDIPPPHAYHHSRSKHPGALDVLGKVFKREGFFGWYQGMEAQIVKAVLSQALLFMSKEQFEKWTLAFIVLLAQMRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXM0</accession>
    <name>A0ABQ8VXM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_482663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046106198" evidence="1">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="15889" checksum="FC17B45409B97E20" modified="2025-10-08" version="1">MRLNFACIVAALLASAANVHAAPLTAAGSTGSDLRIRGSDVIETRNTGLVNVKFMSLSAGEDFDSPRIHLFHETIEERVKIALANHFSVPLYNIRFKNDYKNDFALEPKGPSEILVWVTESNKQSFGTLFSINRNSVASEPRVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXY9</accession>
    <name>A0ABQ8VXY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="60334" checksum="307510A5A1AAEFCE" modified="2025-10-08" version="1">MSLKNKPSWKDSHIPVVEYWLFRIKTHLRAYNEFLALGNTALAVHFAQVAWTDYHLPISQNYPKLVPLKKELNFYKMFSLRHPDPNLIDKTQLTCSEVQVQGTWEKLPSPTQGPRPTGRCAHSCWVWKCRLYVCLGVGETQFEVDDVFWYFDCKINIWKHLPNPPETQPVGGLSSVRPMQVWQDKVYLFLGTRTLHVFDLVTELWSSLKTTIRRGTTWPYDSSSSLTSFNTAVLDDKLYVFGGEDGKDPLGQNIFMALDLSANKWEHLSGSSEHVPQSFQPNLRSLQCMWAAPKQRKIYILYGSANRTQARYKHAAGATECDYTYDDFWSWHVDDKKWERERLRGSYPSPRTEAASVFSHATGRAVVYGGYHGNMTTLETKMTIQDTMYEFAFYGDTFIYDPEANIWQHVLVRGFPSYRAMSTIVSDPDTGKIYLFGGYTNPDFVPAKYFSSRAYNDIWTLKLNLPGGHWNPDDLTRDVRAEKMGPWMRCFTCGNCGINWKKEEDGKNTRKNMAAGNFRNDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY72</accession>
    <name>A0ABQ8VY72_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_200603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="348" mass="39163" checksum="7C0304E659FE7699" modified="2025-10-08" version="1">MTGVLFANYDFNSSSSLSSPSRSRPHQEKRPLNSPGPSTNNTPSKGTSSLKSIFGSPSTNELTSPSPSRSEPIFATPSKAWVPPFPGSPSFSRPQRPLDKSNLGYLAFPTAVSPLAATSNLTSEALDKIHILQSSHSSPSAEKTNAPPPPHVDPLEEKHRARLEREEVERVRGEEDWVRSGGILRDSEGKRDFARTEKVREEIRLREWENKVQERWDGYERRWAELQAKERKGDSKYTFQDIPWPVHVGERDVKTKSRISGTWGTVTLTANVELPDLNRENVEKFLTDGLKVRGCKVTRKERVRTSLLRWHPDKMTALVSKVIDDDRKDVESGISAVVRCLQDMNSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYH7</accession>
    <name>A0ABQ8VYH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_915324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="428" mass="49170" checksum="521CEC89D887B086" modified="2025-10-08" version="1">MLRNNRPNSSLEYLRPSPVRGQLEPQDPKTTKGWRYLQTTDTLDELKVLIPPNTASMYEQLLKLETLELAKKSVTWDRLLEIRHLKDRMIRKCQKLSKTPPARRIGHGDPFTFQTLVAPLDFRLKEMEKWFRQQQTRISSVGTQRPTGHTHKANPRNSYCCARCASNPQYRHHSKAKLSSFDNVTPIPAFTEEPEPMIPSPSPTPPKAISPEPLPHLLRSSMAMALMNQNYTTTTVTTTLQAETATRPEGTVSKIESTSHKLRHQRSCIKRSNTGDSVKTVSWADDRDLMERVGKFTNATKEAQEIGTSIHTFLYRDDEWEDIRQAYVNHMDHLESLEEQVQNSLRRLQIESATLQQVCANIGQHKESLREVVGRFGRKQSDYRAKVQEVLSEADGLLSLYGTREPLENRNKFMPIIDEDSREEPVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ19</accession>
    <name>A0ABQ8VZ19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S2, flavodoxin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_785115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="34621" checksum="75B21F1E50272045" modified="2025-10-08" version="1">MHSLRLRLSNPVRFSFKFCKNCTRQLSQQAQGPLETENDWTDFQQTRTSLKTLMDAMSQYGSTQTSQWSLRDSLHRPTKDATLSALLASGAHFGHASSRMNPNFLPYAYGTRAGITLIDLDHTLPLLRRAAKVVRAVAANDGQIVFIGTRADIRPVVQKAAQRLGTQGFHVGDRWLPGTLTNKWQMFGHETVRSKRIVPDLVILLNPIQNMNAIQECALSNVPTIAIVDSNVDPRIVMYPIPANDESPRTAEIIAGVLSIAGREGIAIREAETQRMRMAVDSAWEDFNKMQVMQDTRQPQRSDAEAFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ63</accession>
    <name>A0ABQ8VZ63_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_906973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018824">
        <property type="entry name" value="Conidiation-specific_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052670">
        <property type="entry name" value="UPF0654_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576:SF1">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10346">
        <property type="entry name" value="Con-6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="14713" checksum="42B6D2532F80FD66" modified="2025-10-08" version="1">MSSASEQHQHHVAGGLKAALHNPNVSEEAKANAQQRLENMGVATETEAPSYDEETNRVLGGYKATLTNNQTSSEAKAHAREVLEAAGIEVNLDNTSDEHQTRVLAGYKAALNNPRVSAEAKAHARDFLREHGTGESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZR9</accession>
    <name>A0ABQ8VZR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_913160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="21541" checksum="B615CCB6A5379CB8" modified="2025-10-08" version="1">MPPYENSLAGQSISEKKNMGHPFSNRHLGPGGSGDRNESSVTCSESGTVSSPSASFSSILTPVVTPSSSSVPPSAPISSTLATSATVLPSASAVPSSASNSSALSQSKVNAGAIAGGVIGGLVFIALVILGFIYVRRRRRLHTAPSAEFMSGRALINPLGSAPGAGRSTSQFSTTSQLSATPRDAFAAAPPAFTPGNYPYPFPEKLGKMIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0P2</accession>
    <name>A0ABQ8W0P2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_805008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF337">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="47"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="520"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="642"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="701"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="664"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="756" mass="85265" checksum="5F8B6230C1C0F872" modified="2025-10-08" version="1">MNPDRTHSAKLQAFKKVYDHLFHSTSSLSKIRDSALADRLLDYTNDSMEVVGRSLVWKFFLIADEPLKSTSNVVKPETLLRSLQSSRKRYADLLSQKMIAPDGSYPEGFMVSGSSNPSPRRDNPFLDLERNNPLSLHNDNPWTEWFAAQELRKMIAQDVERTFPEIDFFRNTNVQDQLTNVLFLYSSMNTSTGYRQGMHELLAPLYYAVDVDSLLDTHESHLISELCSKIWVAADAWALFESIMCFASRWYEWRENPSTYALPSPLSNHIQLNPDGQAQIKPYIAPIVQDCNQIQAILLHTTDPLLWKHLQSSGLEPQIYGIRWLRLLFTREFSMSDAMRLWDVLFACDPTLDVVPWVCVAMLIRIRNLLIPGDYTAQLTSLLRYPTPVLPLDSTNTVHHTSLLMRQALALQLAPTPSTGVSVVAENRNLLDIPMEVPEPPSTPRRKGPPQSTATRNRSSPTHARQQSFQPPGGLPEMLGGLFERGESLNINKTLMSAVTELKRNIPELAASFVRSPLQSPSIPMTVERQSQQPDERPPWEPKSRRELEREMAELRANDKHLGESLSWVVDTLLQDEDTSQDPQRLKKRKQEALESLSYVRDVLINGITEIEDERLYGEAELANRKFKAREPAQAREASLVHAHTLEMPKPAQPPVADTRPRISGNNRGHTTAISSSSSNAPWSPNTARLAPWNYTKSSFSIDGSLPATTLPRLPPPTSDNFQRSHIGPGPSQVISPPTKAPPKRDRTPDPLGVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W119</accession>
    <name>A0ABQ8W119_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_785955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="448" mass="49555" checksum="C62E4EF3B3486A02" modified="2025-10-08" version="1">MQDTVAPVFTRHRAAVAALNLASLTELPFANETNFAVHCPTETDLAVGFESITLAATPKTPNLSDDSDSDFEYYPPAYSPITMPSVLSSFLDESVTYAKWKPSTGGMPGTMTVGKITIETLEAAKKDLRIFLTNNRKLIPADYVSRCLNVWEDPRVSNWIEQNREKFSELSFEDFFIAVRDRVLDPDWRDSTFRKMRAVHMPDDLSTSASDLAVSLLILNGYLKGTRSYQSDESLKSMLEAAIDPGLYHAYTKEVEDQSSNPGHGIHSKDFDTFTRALQSLDHSRHIQLRMARQMAEQMIRSRPGSRATTPFNSSSAANRPAQRQTNGSTVGSQNTVPRGRLPPLTATERRLLGENDGCFKCRSFFVKCRTSSEEHEFAIPNGTGYKELTVADVEAARKLRGPNQDGHKKPRIATTVATIGTEDDDDVVASIIPSAVLGSGTDSEEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DK20</accession>
    <name>A0A9W9DK20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_433269</name>
        <name evidence="7" type="ORF">C8R41DRAFT_889277</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000024">
        <property type="protein sequence ID" value="KAJ4474122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DK20"/>
    <dbReference type="OrthoDB" id="202672at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024512">
        <property type="entry name" value="Ser_palmitoyltrfase_ssu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11779">
        <property type="entry name" value="SPT_ssu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="122" mass="13796" checksum="112109148D73CA4F" modified="2023-11-08" version="1">MIPDIPPNYPPARPDLKAFRPPKSQSKIAYWVWRVHMWIEGTFSLAMLEPWEKLLLLIIFLTTFTLLATGIVRYLPHHISVMKGRAVYYLWGSESGESPVFQWLGKTAGSNGGNPGIPMGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DR18</accession>
    <name>A0A9W9DR18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein eS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS1</name>
        <name evidence="8" type="ORF">C8J55DRAFT_535715</name>
        <name evidence="9" type="ORF">C8R41DRAFT_885706</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the eukaryotic ribosomal protein eS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DR18"/>
    <dbReference type="SMR" id="A0A9W9DR18"/>
    <dbReference type="OrthoDB" id="9834376at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03122">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_eS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018281">
        <property type="entry name" value="Ribosomal_eS1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027500">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11830">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01191">
        <property type="entry name" value="RIBOSOMAL_S3AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="initiator methionine" description="Removed" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="modified residue" description="N-acetylalanine; partial" evidence="6">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4481446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4482685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="256" mass="29423" checksum="36193EF6E9EF9065" modified="2023-11-08" version="1">MAVGKNKRLSKGKKGIKKKVVDPFSRKDWYDIKAPSIFDVRNVGKTLVNRSQGLKNANDSLKGRIIEVSLGDLNKEEEQSFRKIKLRVDEVQGKNCLTNFHGMDFTSDKLRSLVRKWQTLIEAHVDVKTTDGYLLRLFAIGFTKRRPTQVRKTTYAQSSQVREIRKKMFEIMTREATNCDLKELVQKFVPEAIGREIEKASRSIYPLQNVYVRKAKILKAPKFDVSKLMELHGESTDETGTKIAKDFKEPEVLESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9E089</accession>
    <name>A0A9W9E089_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_166473</name>
        <name evidence="7" type="ORF">C8R41DRAFT_74097</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000003">
        <property type="protein sequence ID" value="KAJ4493745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9E089"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23165">
        <property type="entry name" value="Prefoldin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000005">
        <property type="entry name" value="Prefoldin subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016661">
        <property type="entry name" value="PFDN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100:SF9">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016477">
        <property type="entry name" value="Prefoldin_subunit_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="27"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR016477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4466367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4493745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="131" mass="15092" checksum="816A5904C2B9981F" modified="2023-11-08" version="1">MRMIEQDQENDDSTEVTWEDQQKINSFSKLNTRMKGFEAKVDAAKQEKEALDDLSTELELADEDEPVLYKIGETYVHMSLPRALKRLEKDQTDLDVRLTKLSESAQQCETDMKQLKVALYAKFGSAINLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXU4</accession>
    <name>A0ABQ8UXU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="31469" checksum="E2C5A8CAE4FA13FF" modified="2025-10-08" version="1">MTSTSSPTRSSAATTLLPTSLLEAQVLLAGIQSKSTLPLFFESPVFQHLQAGDYSPPLLDSQHSPDYDGSKSEEIYNVFEEAAPFLLYLHDFWMGRANCPLFAEHILLTAEHLSHSLPAFLRDNLEQQWGIPPEHRSPGSGVLNLEQFPAIPIPFCLRFRKGSAIMRMVSSKDLDPFTSLRGQGVLPGVPKIASPSKVSDVILPSSTTKAPAVPPRVLQRNREVESLKADASSFLASPRSICSKDSYNELPSSFPLVDAAPQVSSSAKVSVGRKEPKSKTTVKSYSFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY09</accession>
    <name>A0ABQ8UY09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_783578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000156">
        <property type="protein sequence ID" value="KAJ4463624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="2">
        <location>
            <begin position="241"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="423" mass="48505" checksum="EE7FDC92768E50B7" modified="2025-10-08" version="1" fragment="single">YCLFESAVTTAYTQDADPFLLERLGDDIETFASIVNTQESIFNENSEWQTLWMNLQAMLADVWTIEFLEWAYTQRTTSGITEYLGVAHQTVRQTLLDYGIAQPGINPFPPSKVHSGHTNSENDPVLDQDGTLPQELPDDVQDAAASIASSSSSSGYLSNLSDGDLDRVVKALHSHYARAGICMLQGMLRRLGHIVPYERVQLSLIRIDPIHRVFDRIHIRRRQYEVPGPNLLWHHDGHHHNSVHNVRIEHLWVDVSHYVSQHWHDAFTVLEVHHDLDIQNVNHIWLIHHLFLCQFNDSLVFWAKSWNSHRVHKHNGPSCSPEDRFGFDMFVQGFRGEALDRFAMTDEELEVFGIDWEGLEDEVLLRSLHKNVVDPPSDLLTSEQLDALSMALRCIPRGSELGQIIDLWTNALAYVRTIYPGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYR3</accession>
    <name>A0ABQ8UYR3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_803440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="3">
        <location>
            <begin position="75"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4466183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="498" mass="56406" checksum="CEFCA525696D9199" modified="2025-10-08" version="1" fragment="single">MSQANSTDQDNREQNVPHSQGTTGRNIKKPEFDQSMLGIHSNYSPNTGGRSFDYTEKYAEEPFGEELKDNSRVFKVYLDEAEIFDDDMIRGFRETIDSLLVFAALFSGVVTSFVIATISALQPDYSQITAVLLVEQVQILRAAGNATAINAIPKSTVDLQNVSVATDDLWINGLFLASLSLALATALLSVLVKQWLQAYSSILAGSAKQKALIRQFRYAGFEKWKVPEIVGILPLILHTSLALFLIGLSLYISELHSSLSWIVVTVTSLAFAFYVGSFLIPQVWLECPYRIPLLFVPAEYIIYPSKVLLWLFKWIIAKFQEGFRTGKEEESSFDDISTNSVQKNGFPLLLQASLRSTEHDHLGNNEAKEPIVADILVWLLSLESNQSIQEILAQPIGAFLMDENWESLYCQLQNDADRAAKAIWVTLSKFHESDFERLNNQVLSIFEAFSRTPYWDHFKKGTVDYWNHLVFKNESKIISKCFEYCMPHTRGRIDVEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZH8</accession>
    <name>A0ABQ8UZH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_781455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17934">
        <property type="entry name" value="DEXXQc_Upf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13604">
        <property type="entry name" value="AAA_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="5">
        <location>
            <begin position="588"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4465724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="761" mass="86282" checksum="4361138B32688ECA" modified="2025-10-08" version="1">MGNINQTILPLPPSSLSVYYYRRQLAGHAARALSEVSISKDGDIDTQLGVFGVSISQLDDGAIDHIAFATDTAVYLIEVGGNARGDGALDRVFQKFLGSTTTVLAGFGMPRISLRLRHNLGYHVRGVDLSTLFSSSTSAWRPSKVVQKLCAIDNTFRVDSLWHENDQEGSVEKLCLRAWISAKVGRSEVARVLIENVRKVDTRHVRKDILSCLGILLQQTDVLARAVPRVTHSEHESYGFSKDGKMKLQNSRYKTRVRVSKQSYVEVVSRTGKVYQGEAVRAKGKTTEIAFRQGISEASNISSVRIVGLEEPTPAEKARETLLLRVLKDEDKLLDADFVRYLWFRTREDEQILLYLSPDFASSTHSNALKPYVRHLNDSQARVVTAMTSNDPIVIVHGPPGTGKTTTISSAAEVWSKMYSLPVWIIGHSNVSVKNIAEKLLKRDVDFKLIVSKEFYVEWHEHIYEKIAARLIRTDELPDNVLGMSRLIGSSTVILSTLGLLSNAALETNGLFRVVSVERLVIDEASQINVFEYMHIFHKFRRSLVKVCFFGDSKQCEYLFNPIILPPFGQERVKTLQSIFDIEYLKPTSYFLDVQYRLPVPLGEFISMKVYENQLKSFHSITQYSCVRFVDTPRGVEERSGVSWINLGEISVIVNLIKNYYRKKDFCVITPYDAQRAAIEKQLKQENIPWEKVFNVDSFQGDQHPFLFTSHNVTFLIIAIRERGRLCSSLRCPFYPRWILALATANERHANSMSPRYSYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V053</accession>
    <name>A0ABQ8V053_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_925622</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337:SF0">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4467773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="493" mass="55039" checksum="3DEF628E28292B38" modified="2025-10-08" version="1">MSSKPSWSPSSWTSKPVAQDVEYPDRKGLSKVLSKLETLPPLVTPSEIERLRYQLSLVQRNEAFLLHAGDCAESFDACTNENISAKIGLILSFSLILIWGARLPIVRIGRIAGQYAKPRSSRTEQVGDREVLSFRGDNVNGLDIDDRTPDPERLLRAYFHSATTLNHVRGLLTSGFASLHQPRDWSLSHVRSPSLRNEFESIVEDLTDALDFSRTIGQDAGASFELGGAKSTVGEVDFYTSHEGLMLDYEQALTRECPVPKSVSSVPNEKAYYNTSAHFLWIGDRTRQLDGGHVEYFRGIKNPIGIKVGPSMQSDELVRLLDIVNSEKVPGRVTLITRYGAGKVENYLLEHIKAVKLSLHPVVWICDPMHGNTLTSNTGLKTRHFRTIINELTSCIRIHSECDSRLGGVSLEFTGELNDEGFSVTECLGGSMELSEEQLGLRYQSFCDPRLNFEQSLDVAFLISKHYKDERRGKQKGMEKDVLFTELSGKPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0J8</accession>
    <name>A0ABQ8V0J8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_778845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="92"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="18452" checksum="1990F2858676D71E" modified="2025-10-08" version="1" fragment="single">ADYWRSLNRAGLLEGRVHVVKDQKYQIVSIGVWFEAGTICFKRSDAQCALGFNDFFAKLTPETREWWSKARRSHDVNNLKEKAHRWWCANPATDPEYQGRGYATRIVQQALKDAKENGCTLGLATGPEHNVQKYLAMGFRKRSQGPMPSPTGDFIIHLLSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0M1</accession>
    <name>A0ABQ8V0M1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_782934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000143">
        <property type="protein sequence ID" value="KAJ4464282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="27931" checksum="F64BA9ADC558CD53" modified="2025-10-08" version="1" fragment="single">HRSLAYEMLHNAMIGPVGVGNPFFTAFLHGFRLSCVGGTLDLYDVSYFYGGVEEFVQSSETSVIKDLNDLSFEIKVDLEAVHLNELADVFAEAGPFFEGKIFEDIFNDFLEGTGAPCPQLLHAIRDRFNQQINLAEITSSTFRLKLLCWSTTGAPRIIQEGNPIRVILVEDSDPHYISSTTPNEEHDRYIGSGTCSFKTCTRSCRIPASFLIKLLCSSYDPLSECKDARTAIHHWLLVQMLDAIGCYTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0N5</accession>
    <name>A0ABQ8V0N5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="10">2.7.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_856444</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="10"/>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09135">
        <property type="entry name" value="PLDc_PGS1_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09137">
        <property type="entry name" value="PLDc_PGS1_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586:SF1">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000850">
        <property type="entry name" value="Phospholipase_D_PSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4466802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="548" mass="61995" checksum="582061DFFE36CAB7" modified="2025-10-08" version="1">MLLSLRSNVLRSSLNINSLCIALRLSSTCATRKFQPILHDITAELKQHQPKFSIPADGIRILSQPSEFYSTLLNMIRRAEERIFLSSLYIGSSENELITTLMNRLAEKQSLHLYLLLDLNRSTRPGPASTAAILLPLLRAFPDRVHVSLFRSPNLRGILAKIVPPRFNEGWGTWHAKIYGVDNDVIISGANLSRDYFTNRRDRYIRFTAQAHLSDYCFDFLQEITPFSYRLLPSEATTLPNNNTHRHSQICGDYALIWSDPETHPHRIGDKMQQALTTFQATNRQKFEEEEKAGRPCTSSSNVTLFPIIQAGKFRVREEEQFFQLLFGHLKKAAMRAYLPPVGSLPAGVSSIVQERPLMDLTSGYFSLYHPYQKLFLLHPQVEVRIVAASPKANGFYGSPGISGRIPEGYTFLEQKFMRAVRRTADRFSIFGSGQSNIDLSEWEKDGWTYHAKGLWLSPSADSSPVLTLFGSTNLNSRSADIDTELSFVMALPPSTASPTANDSVETLREQLAREVAVIREDVKPWKGDSRKVRWLTKLIVFLVGKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V113</accession>
    <name>A0ABQ8V113_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_859418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000135">
        <property type="protein sequence ID" value="KAJ4464718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF37">
        <property type="entry name" value="ABC1 FAMILY PROTEIN C10F6.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="131"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="613" mass="70081" checksum="5A2B5000356BB063" modified="2025-10-08" version="1">MFQHASLLSRASLRRTYTTQISPTRWQKYLRRASLVAFSVGSFYTADRLFNASSITRNLRTLYTCAMITIDYKLNFTEEKSDQIPELHTRVADRMYNLFTSNGGLYIKIGQAIGANAALLPKPMQEKFARLFDDAPQIPYSDVLHVFKSEFGRPPCGPDGVFEIFEEQAIASASIAQVHRAKLRPLPGDTEGKWVAVKIQKPDVAKQMKWDLGAYRFVMYMFEKWAFDLPVYFVVDFVSDHLRRELDFRLEAENAKQTAIFIASEPRLAKNVYIPKVYDELTTKRVMTAEWISGVRLSDRNGIRLLMAENNDPVVVQATVPSFVDTSEDNAPPSFSFPPTPLKGGVRYVMQIMVELFSAQMFSWGWCHADPHPGNIIIRPNPHHPTLPQLVLLDHGLYVRADEEFRRDWASMWKGLLTGEFKSVERTTRKWGMGLPDMFASVALARPVRLTRKDRKAEAERVTRELEEYMSLSQYEQSVRMKAKLKQFLTDTDRMPKALIFLLRNMRIVQGNNQSFGAPVNRVKIIGLWASNSLTRLPNLTIGERLREYVNDIVFRSVLLSLDLAFWTTRLRQRIFAMFGLKSGSFEDELEKAMRGMMKSSVGVEVGATAFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1P8</accession>
    <name>A0ABQ8V1P8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoplasmin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoplasmin-like" evidence="2">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="246" mass="25917" checksum="34D16BDE6BD2C8A8" modified="2025-10-08" version="1">MSFWAKNITSGSSVELVLSQDLRITNIAISDDYKDALGRTSLVLSSTRNNANSISQLFTIANLLVARTEQVLVNVKLDQGYKYILSCRGSNDLTLLGYYERNLFNLPGGTNFNPSVNPAHRTVAPTLATSTSAPTNGATSTSTSSRTSSVAQSSLLNHRPIAGRVTQKSPAIPAAGWSHTAIANASKTGPYSTAIASQISDPGDGNTTPCSFDSTNEKPGTYDMRVSSGGFINNFPSSSNNNAGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1T1</accession>
    <name>A0ABQ8V1T1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_778930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4468094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="106" mass="12576" checksum="3D282C7B4D29F478" modified="2025-10-08" version="1">MSTLRRSGLQKDVLNIYRRALRMVKTKPPSTQDKFSLYIRYTFRSNASSVSPRDVSAIEHLMRKGKRQLEMYEHPSVKDCWVSEEMRNWEKHQASKSKSNPQFKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3H7</accession>
    <name>A0ABQ8V3H7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_851734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Preautophagosomal structure membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ATG12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="4 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="124" mass="13918" checksum="40B7C4B28A25D0C3" modified="2025-10-08" version="1">MTDSADRSLPSWASPEISETNEEALKALQTYKKKDADKVIVRFKAVGNAPIMKQNFFKITASNRFQAVIQFLRKELGYKGSEPLHTYINLAFSPAPDDTVANLFKSFQTDNHLIVNYSTTAAWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3H9</accession>
    <name>A0ABQ8V3H9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ectomycorrhiza-regulated small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_73526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047048040" description="Ectomycorrhiza-regulated small secreted protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24762" checksum="3DF4C04F042C1385" modified="2025-10-08" version="1">MHFNSKACFIFILLRLLSVSYVTALPAKPGSLNSKPSPLIAHGERFPILRLTAVVKYDKTPYQWKGRIPSLVDSNPLLSDIHTLIEAEIRADKAVQALHAEEVVVMFLSRGRPPRFDNNTHDFGFHVRYYDGRHPEAVSSCENGKLTFLPRKKLDDEVNSVVMKERSLDFTWRYMQHFYPMLQPSTSAKKPLNPAAHAFDPAKKPESPYDLKVEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3Q9</accession>
    <name>A0ABQ8V3Q9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="25534" checksum="C97578906053E477" modified="2025-10-08" version="1">MDAQPHFTRSQARAAPPGEDDPAPRQSLSLRQSILGPPPGEVADTPVTPPPTFVQPAWIIPHPNSKDALCAFEAIRASRTSTQASNPAESPSFSPLPCNDPIAQFSHASSTTRGSPMAQDSGHSDDGWFGVAGSDIYDPNDAYATSSEEGAGPAHHSHSRLVFSSPTATDFHRDTPPVELSPSVALEDFMGIPPRVPSAAPTASEHRWRAPRGPFRDPALAPVPEPLDSRPGLQPAPRAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3V0</accession>
    <name>A0ABQ8V3V0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_855436</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000107">
        <property type="protein sequence ID" value="KAJ4467512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="47"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="670"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="824"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="984"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="303"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="674"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="877"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="895"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="984"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1067"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1091"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4467512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1360" mass="147937" checksum="6CA51540DA1EB3ED" modified="2025-10-08" version="1">MTTTRIHHALPAPVVHAGFSVPQSKSHVLAGVQDAYWSDDEAEDAECPLCLEEMDISDLNFKPCVCGYQICRFCWHHIKENLNKRCPACRRVYTDEAVEFKPIATQDHKRLTQQKKQRERERKELDALGRRQLANVRVVQRNVVYVVGIGPRFAKEEYIPTLRSSEYFGQYGKINKIILVKRNSSGGGAPVVGVYITYHRREDAARAIAAVDGSTSPAGGRELMRASYGTTKYCMAFLRSVSCSDHNCMNLHEWGDEKDCFTKEDLTTLKHTIKTTETKARSVISSKRGDEADGLPRSAAWGSRTNLQPTVPNIVSTQRKRVSATTRQMRPQTEARPSSRPQEKKSSAKLASQETLSRPTTPASTLPLAHPSLPPKPPSPVTRKKKEPIVRAPSPSPTPSAAGDSESTGSQENGPGSPKIHPQSDESIQSSIPSNPSAPPGLPAVPPGLSAPPGLPPPPGLAGPSHPSRIATASPQTPILAQQTSYQMSNAARALLDDVTSRRESLLPTVVAQSPFPDFDRTLENLSQADGGLGGFSFSLDLNLAGDEAIHDEFADLEPESQTPFLGSFLDAFPSLRSSASTSSYIPPGLPYPHNPAHAIYDPTVVQRTVTPIENQSSNKPNYMGSFNPFADGADDSPTVSAPIKPNTPNAIGDDSAPRVSRFGFARHGPRTATAASSPLQISSTMSTSSNNEANSNIFGQSELPHSPAVSQWSLHGRQDFGYSSSNSAAPSPMMPAQAQPMYVPSQSRFQPFDSSAGVSEAQLRDFIQSNQDRPNLLRHDSQGLYKGAQPQFHDPAIMSAARFAPASESHYMHPVDMTYGPPPGLSFPPGLQNLNTPVSMNDGNGNAHELRAEPVAEGPSLSSPSDFPALPSSIISDPTSQDTPSPSTTTPIEQDFKSQEKAERKAAKKAAAAAKAAERQKIAQEKSAAKAVEKARIAAEKAVERERAAVLKAQLEKEKAEKVRLETENARLEKEKERLLRAERERVAQAEKDKAAKKAGVTSARAADTQKATNKRVDTKATNVKEALPGSSEFSTQVPLLSKKPKKNKPVTRPIRVPHKEEELGTNENSSYPSATASDTAHTSGFKGPSTTTSSNNSRSQSLERHVPTSLEDLMEDIHIMNASMDLLKHPFFDLHKINPAAKMPLEYGPLVHALSALSVGGGSFANNVPSGSIDNAVSSFQQLLETLTQTISDLLRLLPRTTWDDNSSFDGVLRDMLKGDDLFDEGAAVATSGEDGHGREDEVATLTLALERRARWMEAQLSKLEELHRDINNAAVRAVLAFNDSGWDRHGFMPRIGNTVRRFENIGVVDDCDGQRPMTAEELEKKLVVAKEAAVFAETELREMMEKMQDVKPYEDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4E3</accession>
    <name>A0ABQ8V4E3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_849137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="10585" checksum="A4024FE188CBB4C0" modified="2025-10-08" version="1">MFTRARVLAGECCSALKALPAVFQYCWEHFPSWTVLSVECGQSSSQHGRTLQRHQHLLVLPQKQKNRNHTTLSKGASDSALAKWSAKTSGFLNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4S9</accession>
    <name>A0ABQ8V4S9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_775212</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="374"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4474208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="426" mass="46224" checksum="238A5CA876A4909F" modified="2025-10-08" version="1">MEDGGVPNTTLLAKLTRQYLFVFAMVMGADWLQGPYVYSLYREQYKFPERLVALLFVTGFSSGALTAPLVGAWADQFGRKKICLVFCITYTLSCACIFVRYLPILLIGRFLGGISGSILFSAFESWLISSSNGAGISDSNLSRIMGRASLINGLVATGAGVVSNQLVSSTSNFGSPFLLSGTILVLAWFVIARTWQENYGSSAAEAGTQNISIFQIERLAKAWRIARQDRVLLVLGLTQTCFEGSMYLFVFLWVPSLQEASHSSNILPLPLGYIFSAFMISMMLGSLLYTTITSHLLTSPSKSNGSLSIHAKLSSLVCAISGLALAASVSSRNEKIRFWCFCVFEACVGIYYPVQGMLRGTLIPNEHRATLSSLFRVPLNVFVVVSLLTGVSSARYAVLSASSVMLGFSAIMTGLVIVNHADKYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4T8</accession>
    <name>A0ABQ8V4T8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_911630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="674" mass="76808" checksum="7A9BB74EC2E7206E" modified="2025-10-08" version="1">MLVPIILGADKTTVSVATGHVEYHPLYLSIGNISNAARRAHRNAVIPIGFLAIPKSDRKYDNNDSNLRIFKKRLYHSSISAILQSLKPGMTIPVIRKCPDGHFRRLLYELAAFIADYPEQVYLSGIVSGWCGRCQGIFSDLDGPSSSDRRSRKIDQILREEYGGEGRTLWDNFGIDEHVIPFTEDFPRADIHEMLAPDLLHQVIKGSFKDSLVEWCLDYLTTTHGEARANEILDDIDRRLAAVPAFPGLRRFPHGRRFKQWTGDDSKALMKVFLPVVAEYLPEEMMRCLSSFLDFCYLIRRSDIDEQCLDAIKSSLEAFHHYRDIFKTSGVRNHFSLPRMHSMLHYPFTIMDFASSNGLCSSITESRHITAVKKPWRRSNRYKALSQMLLTNQRLDKLAALESTLVDRQLLLPSGRTQPSDPFDAENEDVGPTDSGHSLVDVKLAKTRETSYPRYLSELGTHINQPNLELLTRRFLHEQLDQSDSSSSISLSDTNINSLPEITSKIDVFHSAVAVFFAPSDPSGIRGMRRERIRSTPSWYGQERRDCVLVVLNEDIAGFLGMSAARVLLFFSFQHRQTKYPCAIVHWYNTYGEQKDAKTGLWIVRPAEWNPQCQQQDPRFAVVHLDALVRGVHLIPVYGSEPIPLGLDFQQSLDVFDSFYVNKYADHHANEILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V533</accession>
    <name>A0ABQ8V533_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_849108</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="4">
        <location>
            <begin position="18"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="113"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4473545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="29978" checksum="2578EA9A6697AF29" modified="2025-10-08" version="1">MQVWAVVFDPPSFTEELYQKGLLLIDPASSARIKRFYRREDACRGLIARLLPRMLLKERGVAPSMMTFAATEAGKPYVTTPDIDPPLAYNLSHDNGSVVMAFVNGKSHPPAYSIGVDVMKVHLPRRNPYRSFVDTFQEQLTPLERELLSPAVPADEGLQRFFWMWTMKEAYTKALGLGLGFDFSRIEFDVVANRVWVDGQVPQGWIFHKFQMTEAGEQYVGVVAELVEGVETIVVPETDPKPWFKSFRAVTFVNRAIEELTQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5C6</accession>
    <name>A0ABQ8V5C6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_905025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="152" mass="16968" checksum="2502B0922A87259C" modified="2025-10-08" version="1">MDSVNGSRRSLPEFKQLLLPVALLRITSSLGHPPDFDALLADIYFSLNTTTIQPSFQVSCDILFLRKDIGAICYIGRKSRAYVWLSMGGCIWSDHDGNWDVGAEKLTIEDNRSSRFRSIRVRRALTITQVRAAGCRLDCSQSTGEPSVKDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5K6</accession>
    <name>A0ABQ8V5K6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uracil-DNA glycosylase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_847256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10028">
        <property type="entry name" value="UDG-F2_TDG_MUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015637">
        <property type="entry name" value="MUG/TDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159">
        <property type="entry name" value="G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159:SF9">
        <property type="entry name" value="G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="5">
        <location>
            <begin position="111"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4475449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="308" mass="34409" checksum="07DB5E3364889A7D" modified="2025-10-08" version="1">MSFPDPATQEAVSNGQTDGSKSLEQESDAVTESRRRFQTTISRFSFDGSGGKQFPSSSTSPRKRSRTQQERSLTPEDASPSKKAKRRKPTRGYSSPEVYSHLSHLNDCISESLDIIFCGINPGQRSAEIGHHFGHPSNHFWKCLHLSGLTLERIPPAEDFTLPERFQLGLTNIVERPTAEATELRDSEFKKGIAPFLAKMARYRPRIACFIGLRTGRIVLDHVMRARPKSERPTFSPVLQPYKIIHSEPSGPSEGVPETLFYSLPSTSGKTQGYQIPDKVKLFAQLKADLKELKDGNLSTEKFVEISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V618</accession>
    <name>A0ABQ8V618_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_847464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="95"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="142" mass="15526" checksum="DF7CC26D6BBCEE64" modified="2025-10-08" version="1">MSTLLQDVLRSKTTADSKLIERKLNSLSFSSIRGANNNPPSHNNNSDDSDDELVNVVSVPGTPSRTRPPSPTRGGAASRPLRRPLHISSSPVPKTDPLKALPTEISQKIFTKLPVKDLAKCALVSKKWHRSQTINYGMLAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6D5</accession>
    <name>A0ABQ8V6D5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_544261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14468" checksum="6B0E91050A601E6D" modified="2025-10-08" version="1">MLIIVLTSPSLSSASSSFEICSALTVTSARLDASTALLQPTRTHTIIRYNYLIGTLNILHTYVRYPTPALINQSVSHSAASAARCYCAIRAIFKDEDAQDNKQIGRVETFQLLYWKGPVHCRPIDTTHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6U5</accession>
    <name>A0ABQ8V6U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_904712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045356696" evidence="1">
        <location>
            <begin position="23"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="154" mass="17451" checksum="E963307167E7B626" modified="2025-10-08" version="1">MRLLMSFFLFFGLAFIMETLEAQISRRGILARTEETKGTYENPLRLGITFLGKDYHWLPQYTVKVTGEYQTEVEKIIRKVFKSQTVEKILGVVEIESFKGTVVASGHAQVFFSISGDANPDPCFEGNVVTNTGFFTIDRRKGDSITNSHLIEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7J0</accession>
    <name>A0ABQ8V7J0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1295-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_844333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF17">
        <property type="entry name" value="STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32549" checksum="B273FB91298A6D44" modified="2025-10-08" version="1">MAVFSKIFPSLATSYIVQAAFALAFVPQRNEKYYDLGGAVGFISTTFASLYYPSLRESVIRGKILPLPPLSHFAPRQLILSAALGIWITRLGSFLVQAFKAGGDSRFDEVKHKPVHFTFYWFMQATWVFIVGLPVYLANTIPKNVHPPLNTRDYLSIGLFASSFFFEALADRQKTIWRRSRDAKEHDEKFITSGLWSISRHPNYVGEVGIWAGIWGLSTTALQTPYFPRGTVAIAAISPIFTYFLLRKLSGVPPLEKAGDKRFGTDPKWHEYKRTVPIFWPWSSARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7J1</accession>
    <name>A0ABQ8V7J1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045244004" evidence="1">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="18928" checksum="F0AB830844F373D4" modified="2025-10-08" version="1">MLFRNVFALALVSVVFANPFGKRQGTDTNAQILPPLDTLASKVGVIMPEIQLLQVSHQANDTSIGAQIDMLVAAWNTTTSALSGIPPSIGSNTTTPTDNDLAVSLGDSLSKVTSGLSALTPAIVPDINTLLTSLDGPIAATVDAFNASAPAQASTFVHILMLDARQFFADENMTQTLAALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V885</accession>
    <name>A0ABQ8V885_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_775185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="43"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="475"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="518" mass="55970" checksum="4432E3591E705D1B" modified="2025-10-08" version="1">MVSALSQLWSNATHNLVPRKEKTTSEKSLLTALTELNARQWAEFWTGWLAWSCDAIDFFSVSLSVTSLAEQFNKNTTDITRAITLTLLLRSVGAVIFGIISDRYGRKYPLVFNLLLVCVLELGAGFVQTYSQFLGLRSVFGIGMGGIWGLAASTALENLPVETRGLASGVLQQGYAVGYLLAAVINLYLVPEQSHGWRALFWCAAGISAFAALVRLLLPESAVFLKTREDARLREEKTGLPHGGATKTKIFLKETKKMLKAHWMLCVYAVLLMTGFNFLSHGSQDLFPTYIETSKGFSSHDATVMTIIGNCGAIAGGGIAGYVSQHIGRRLTIIIFVLLVACFIPLWIIPSSFSGLAAGAFCIQFGVQGAWGVIPIQLAEMSPPAFRATFPGVAYQLGNMVSSASAQIESTGGDHLKTTIAVPVSSDYPDGRKIVPDYAKVQGILIGCVAAFVLVVTLFGPEKHGRQFEKHRAAFEEGGGDDDAEIGDVAPTPRDAETSGEKDSVDVKTHDHHEIEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8A9</accession>
    <name>A0ABQ8V8A9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-arabinitol 4-dehydrogenase</fullName>
            <ecNumber evidence="7">1.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_497987</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17399"/>
            <dbReference type="ChEBI" id="CHEBI:18403"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.12" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF12">
        <property type="entry name" value="L-ARABINITOL 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="11">
        <location>
            <begin position="45"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4479853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="385" mass="41514" checksum="624B8A749FE22F2F" modified="2025-10-08" version="1">MSNTQLENPALYDPRKVLDHPEFRVLTSGEKPSKESNIAAFYNPAHEIHLVEKPKPKPGPGQVLIHVRATGICGSDVHFWKHGRIGDSMIVTDECGSGHESAGEIIEVGEGVTEWKAGDRVAMEVGVPCSQPSCNACRTGRYNGCPDVVFFSTPPYHGTLTRWHVHPAKWLHRLPDNVSFEEGSLCEPLAVALAGIDRAGLRLGDPVVICGAGPIGLVSLLSARAAGAEPIVITDLFQSRLDFAKSLVPGVRTVLIDRNATPKDQAELIKKAAGGPLQFALECTGVESSIHTAIFSVGFGAKVFIIGVGKNEQLFPFMHLSANEIDVQFQYRYANQYPKAIRLIAGGLINVKPLVTHRFALEEAVAAFHVAADPAQGAIKVQIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8H9</accession>
    <name>A0ABQ8V8H9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_773567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="135" mass="14499" checksum="2116F389DF226E65" modified="2025-10-08" version="1" fragment="single">MATTKSKTSATFGAPIEVSSVSEWNSILRSAYANNQTVVADFHAEWCQPCKVIAPVYANLASQQPFTYFLRVDVDGNRTRPIAAKYSISAMPTFVVIKRPPGEEGATNATGKGVVVEKLQGADPQGLARITNTHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8I7</accession>
    <name>A0ABQ8V8I7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_922716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02603">
        <property type="entry name" value="HAD_sEH-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4479501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="31181" checksum="06CC0080F04CBB16" modified="2025-10-08" version="1">MVEAHEFKAVVFDIGGVVVRSPFLAIARYEREHRIPENYLNCSIVARGSEGAWQKFERGELELFPFYKAFSQNLSDTVNGNIWYRDFCKRKGIQCPELPDTLRVDGREVSLLQSLLVRFNEGRMKLFGMMMRESSQYDPHILEAIRRIRAADKHKIIALTNNFSRNDTAIPSSELDFLGWQDGATPNKLKALFDDFCDSSTLGTRKPEPRFYLLACERNGIKPSEAVFLDDIGLNLKAARDLGMETIHVPIGGTLTAVKVLGQKLGLDLTAEPPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Q4</accession>
    <name>A0ABQ8V9Q4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_841537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4481832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="87" mass="10309" checksum="032E116A2426F49E" modified="2025-10-08" version="1">MHQRWDYLPPLPEDDQTGYLHPPPFAYNPLHDLESCWWLLVYILLQNDDVDNVLKESASVLQRHDMTVSLFTRTVDTTSWRGRLLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAF4</accession>
    <name>A0ABQ8VAF4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_840441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046932171" evidence="3">
        <location>
            <begin position="22"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4484100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="186" mass="20655" checksum="4DFC9EE6397FCE9A" modified="2025-10-08" version="1">MTKPWILTFILVCSSFLCTQAILNKWEATNFCKCICFQSNYSILHLTLPDTPSQPCLSCTKQWCLNQNLAICAGASLGDTDPDTATGKEGDVEARCFQRDSPRDQLVVTIFLLVVFGLLLGAGIKRRLEKAGLDVGSTWNNGVTWWEHLRSRMPVEELGLSRLGNRMGHGSRSRSEQYVPVSNEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB28</accession>
    <name>A0ABQ8VB28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_896507</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="9">
        <location>
            <begin position="2009"/>
            <end position="2361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="795"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1140"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1296"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1574"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1718"/>
            <end position="1757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1820"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="522"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="609"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="799"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1151"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1296"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1313"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1574"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1614"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1627"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1732"/>
            <end position="1743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1744"/>
            <end position="1757"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="2328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4484639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2361" mass="255896" checksum="D6ACE4EBC32C207F" modified="2025-10-08" version="1">MTSASLVYGPTANLKSDIPTLRPTSIIHRTPWRPPVATYGEGIYLDLEDGRRVIDAVGGAAVACVGTSHPKVIQAIKDQLDRVPYVYNMQLSNEPAEKLAEILIKSGNGAFELCGFASGGSEAMEGVIKLARQYYEEIGQPKRTNFIARQLSFHGNTVATLSLAYHPGRRGPYEAILDHQNYHHVSPAYAARFQHANETEEQYVERLAEELEAMFNKLGPDTVIGFVAETVVGATTGACPAPKGYFARMKAICRKYDALFILDEVMSGMGRMGTMHAWESFGDGAAPDIQAVAKGLGGGYASIGAVLMSKTVAEGIRGKSGIWKHGHTYQANPLACAASVAVQEVIASEKLLENCRIQGAHLSELLHERLRGPNAFAAPYIFDIRGGGLFWGVEFDFDLPEAAKVDMKGQKFGIVLQARALEKGLIIMGFAGGSNLEGTKGDHILLAPAYNVTKAEIEKIVDIFVNTVEEILKSNLAARVRAAKQKSQEKAQDKERDLSAEQSSSSALPAESSRGTRISNKRTREPASGKGKAKEVFTEESTRRRTRRSGLANNAPLTIHEPVKDPKGKKRATPESPSDEDISGSSNKRARTSQSFRFQSSSTLDMPRKTRSTTKGKMVAKAKAMAELESSQHDDEDINMIDPDIKPEESDHEEDNLAEPMEDVEEGQGEGSENVQEHDDDDDGDRHGHDHDEDEDHHEDDSPPAQSGMPGGLDDAAAALAIFGDYRQFGSYMMSLSSRLKTMLNNIKSTADPTTRLVTLQELSELLSISTEDTLAGSFQVEAFVRELVKILGGRGADRDEDDDEGDEEEERDEDAALAAALAMSTGGTYTGDENLEAQVLACRCLANLMEALPGVAHTVVYHGAIPVLCSKLIEISYIDLAEQTLSTMEKISEEFPSSIVREGGLAALLNYLDFFSIAVQRTALQAASNCCRNVSSDHFPMISGVWPIIRNCLSYSDQRLVEFACLCVIRVIDSYHKSSVENLESLVDTELIRAVNQLLMPAGGSPLIAPNTYTLLLRALSTAARASPKVTVALFEADIVDTVYQILTGVLPSTSASSSEQGDAAGGQGLGGGLADMTVMENLAHRPKDQVEETLNGVFDHKAYNEKNLAKMMKAKAKADKAAARAAVQAPLVAALLITPPSAPSPTPEEQPASEPTATSNVSSNTTADRTQLLRSKPAVVGRFMQLTVPILIDVYAASVNTPVRVKTLTGLLKAASFLDADGLKQVLTFVPVAGFASSILSSRDHPTLVIGALQLVDLLLSKVPSLYKPTFRREGVFYEIETLAARSLASSKLKEKEKADKDKDKDKDTSDTGTPDASASTTTSASSSSSAPIIPGYKRLSSIAYDPEDAITLRARIMKFKYLSGDDQAESDHTLQSLKELVDRITPPNASEQELSEALWDLTTLFAAPHTSVSSFELLQSGLVDGLLKFATDTDRKVSLARRKELLLDSLVSRKNRTLSSSQTPFSTFVKKLQESFTRMESFDVITVSQGSDDSKHSSPSLLARQLRLRLVAEDDSGVPRNLQNIVVSIHAIATFQALHDYLRPRVAGVLSNSGSRLSGMLAALAASGFAGSSRVSGSSGEPSRSESSPSAPLPAPEVSTSQDGSSSSTVTRRRSQRLSAKKLGSTSGVDDASTNVLAAATDDSVMQSTNTAADEPEMPPPPAAAESATETLVDSEMQAEFSDEELDAEVFDEEEVDPDNSISDKTVTLSVAEDGSKIEAQTPDGTRVATPNPNISVNQGASSKPSTSSRPSYASALRAKPTDWHLEFAMDDHVLPLDLTIYGAIHQHEMRKKTGSVPPSLFWQGVYTIKFKKVPGPTAASESIKPRSSTPPLSSLAEDAPHAKIVRLLRVLYQLNTLEAEGSLFGGEKRNLPETVFVNNKLSAKLTRQLEETMIVASSCLPDWALDLPQHFPFLFPFATRYHFLQSTSFGYARLILKWQSQQARGGQDSSRRDDGIGFLGRLQRQKVRISRKHILESAVKVFELYGSSSSVLEVEYFEEVGTGLGPTLEFYALVSKEFARKDLKIWRDSDHGAPGADASPFVHHPSGLYPAPIGAEDMANDGGQKRTHIFRVVGQFVAKALLDSRIIDLSFNKVFLKLVVGEEVPLTIATLKLVDSDLANSLTKLLTIAAADKQPPLNDKLAKKLALIEETVTVEDLALDFTLPGYDIELKPSGKDIAVTTTNVQEYVQLVLKAILGSGSTLQAKAFREGFSKVFPIGDLQAFTVEELVMLFGNGDEDWTVETLSEALKADHGFNPESRAIRDLLEIMAEYDVSTRRDFLQFITGSPKLPIGGFRGLNPQLTVVRKPHEAPLTADDYLPSVMTCVNYLKLPEYSSRSVMKEKLGVAIKEGLGSFHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB41</accession>
    <name>A0ABQ8VB41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_507863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053221">
        <property type="entry name" value="Burnettramic_acid_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887">
        <property type="entry name" value="CHROMOSOME 21, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="43299" checksum="13965C3134FC303A" modified="2025-10-08" version="1">MASSSHAENQLSSQISQDADILIQTYLPTLSNGPSKQEISLPFAIPQIIFDDRQESSFARGHCPELGESGFTQQVMLSIVDGLNLAMAASPPIRIVGASGPVVGYLPYHWAKLPSTSMHVDPHTGHRSLARSLTDHYLRTANINIFKPRKLVARICTTSALLILTAKAEKPDDTMKKVGRGALTVARHMPITGLIVRQVSKSKSNENKKQKDEDMYQPIGRRRLSLIEGRALPLSTGGSPPHATHGVMQTMARYGVHLGGTRAEKKEFERRRAMEVFEEAGVTAEGVNNNNYHVDYSTGKGARAIERAERRRRGIGGQGRQVKLEVPTGGEGDLLRTWATDKLLWFVIMPVEKDMEIEDIILAEGAANEENVNHKVWMGEMIFESEEMLDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB89</accession>
    <name>A0ABQ8VB89_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_771806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="34905" checksum="7AE640F648B5C6B0" modified="2025-10-08" version="1" fragment="single">MESLGPSRWSSIRPWIPPLSLSVREITSVSVTFVLSAATSDQNSETELSLADLGLSAEDMHEDEDVADDEDTSTSELDAKKPLSMVSSVLNGGLSVEVDRSSWRRVFIRIDDKADEAVIIVYGLLPGRQYEIVLELVQGGHTNSIRQQVTTEENETKDASHASDSDSTSKSTAASSSSDINVLNTSAQPSPQSDSNGSSPQPSSSPGYGFAPLTLEDRLNQLQHTLSVLNSEQASLTATIKSSRRDAQKADANLRSEIDVLKRASDRYLSSEQRSKQKVLALQEAVKRTQIITKEMEATIKEVNAEIPGLKEEKQKREAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBQ3</accession>
    <name>A0ABQ8VBQ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25083" checksum="71CCAB85B574FB6D" modified="2025-10-08" version="1">MATPSDLTSAGVPPAPGAPPSSPNPATPICSRDLAFARRFLEVHGDPGQRTHYSLPTEQWRLIYGRVEQSTNSTSALLELNPLDDQDQRDLDRQELREFRQQQPSVLGPLSSFPRTSPLVGDSSPPPRAPRRRPEQPVGRSSPPALTVPPVEGVSDYRRVVLVLRPPHVPGSELTTLPEAGQLVPADSSHRSVVDQSRFQGHTEIPHRVPQAGSFEQLVPPSEVEDFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBS4</accession>
    <name>A0ABQ8VBS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_768556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="7"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="59240" checksum="CD9DF3DFBB4BEEAA" modified="2025-10-08" version="1">MYSELPDFIEIRQSEETGRGIWTQSPIRAGSAIFVTKPYAAASSSSKLTSYCSYCFEQTGMNGLRRCTKCRVTHYCDFNCQTNDWAIHKHECASLQNWSKAAPSSDYPPPSDAIRCLSRMLWKMRKQGPYARQTREIASMQSHRSSLKPSAYESHTYLAHSLVQYLGLSSPGDMEQYSLSSAADLVDTISRFVTNTFTVTDPTLIPLGAAVSPVVALINHSCDPNAVVVFPRVSTDPKVQEPLMQVIAIRDIYPGEELCSCYIFLQAFVLTSYIDATLPTNLRQQALNETYNFECNCHLCTSTGLDPRASLNCPKNCGGSCPLPSDEHALVRCSKCKSVVRSVDAALDALRVGQEGLDKANNLQFEDPGKSIRLTTNLIPILTSAGFPPSAHPLLGLTRLHQQLLTSSFPNPLTQEHLDETIHTATTNVAGLTALFREGHPVLALALAELGKLLAVDEPSPRTTNKSVIYPPSGLPRLKLAYETLLRARKMLLIGFGVTNEGGQVGKEVREMIVALEKEIGVFRQGIKNVLEDTPKLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC07</accession>
    <name>A0ABQ8VC07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_773453</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039852">
        <property type="entry name" value="CAND1/CAND2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013932">
        <property type="entry name" value="TATA-bd_TIP120"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12696">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08623">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25782">
        <property type="entry name" value="TPR_CAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="TATA-binding protein interacting (TIP20)" evidence="5">
        <location>
            <begin position="1041"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4476572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1219" mass="133383" checksum="C099AA04532F7A76" modified="2025-10-08" version="1">MTKTYQMNSLIEKMQSPDQDFRFMGLNDLMTEIKQDPQCFLGDETVENKVLKQVLALVEDKISEVKNQAVKCLGQLIKIIRQVQMELVVDKLIEFSGGKDQELRDISALALKTITAELPPDGRVAASACAKLTPKLLAQIQSSDTPSEALVETLAILSILISRFPSHLSASSLTPHPLAVLVPLLSHPRPVVRKRAIVTLSQFITISPPELFSELFTDNVLPYLGPSANIEKQRTTVNLVAAVARHSPSQLAPMLSEIMPSIVKAVQREDDELREGCLQALEILLLRCPAEIGPYVSSIVQVGNQYIKYDPNYSAGDDEDEEMADADDDDEDADLDEYSDDEDTSYKIRRSATKLLAALIGTRPEMLSTIYKDVSPVLISRFGDREETVKLEVWSTYGLLLSQTAVYGGLSQSKEDVTRGKRKRDTETMDVEGGPYSLLKSQVPALSKALLNQLKSQKTSSGTLQAGFGLLYSLLNVLPGSLSSQVTSITSTSKRVLSTSPSTSTATLYLNCLSFLALFFATHSPPIFTSSLPSLTPALLKAAGERHPRVASEAFRVFSALLQAVKPVKNADWTEPLYDQAVARLTTHDTDAEVRGCAEECIGDLWICATDMVRSKNGKEWESICRQTGKVDGAVKVIIKVAKEVNVSDAWVNGCMDWILGLLKKSGRPGKSDIFLAFEVLIRSYTTGVPSGLPSALISQIKPYLSVSDISLLSQALSTLSVLLELAPSTTFPEVEAHVLSDIYAISRSPLVGGTALDSLLNFYAALVRADKQIATHIVPSLVISVDKVPKAESSPANAARCVAQVVKTDHSVAAGTIAEYSKHVKPTSKAKQSTVVLSLLILGELGRFIDMSPQHDIFTNAIEHFSAEQEDVRSAASFAAGNIAIGNLHQFLPAIVKMVQSDAKKRLLSLHALKEVVTHCSHNQLEGVADILWVPLFENSENSEETTRNVAAACLGKLATTHPSKYLPQLHNRINDSSPATRATVVAAIRYTFTDTAPTYDELLSPLIIDFLSLMDDADLTVRRLALSTLNSAARTKSHLIRDHLSVLLPNLYKETVINKDLIRTVQMGPWTHKVDDGLEARKTAYETMYTLLDTCLHKLDLRKFLERVVLGLADESDEIKVICHMLLFRLSQVAPAAVSQRLDEATPQLEKTMKGATVTKDTVKQDLERAAELQRSALRAVAALSKIGAGVSPKFDTFTEDLKKNLTWGAEFKELIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCC4</accession>
    <name>A0ABQ8VCC4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_449943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="192" mass="21598" checksum="1462A3E23929C202" modified="2025-10-08" version="1">MAAKVSLSPTLPVSKRFDSASADMTLQSSDNVIFKVHRLNLEMHSQVFADAGGSTVGTVENEIVSLSETSEVLELMLQYVYLQPQPDLQKVEWELMKDLAEAVEKYEIYSAIGVCSQRMRERLYEHPIDVLLFSVRHKYTGMMNESAEATLDIPPYTMLSCVPPNVFAAWVCQLCIFSDIISSTMYDVGRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCQ1</accession>
    <name>A0ABQ8VCQ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046538354" evidence="1">
        <location>
            <begin position="22"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="226" mass="24946" checksum="93F4E3376FE6A01E" modified="2025-10-08" version="1">MVHAHVALIALFVFGAVFVLAVPVPEDLSSALAARTFKYGKRSSLPSSPGFSTASGLEEYDRDTLSPFGSPKSPVFDRHPAPYIHSDITSTTPNGAILSQINALVLYGPLRNRLRNFPSNSHPPAKPTWNALFDILRNPHDHSSRTKCDDILNCTEKVDANTQLEIIILWISGIITEADRQELKAIVGKLKVKPEETESLDLVDDLWLKYNEELMNYKAALGNALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCT0</accession>
    <name>A0ABQ8VCT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_492708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22756">
        <property type="entry name" value="OTU_OTUD3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF7">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="45"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="479"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="789" mass="84784" checksum="709570693FB0E83A" modified="2025-10-08" version="1">MVSARKQNKSFRTRATRSSGRSNLLTSDPLQNTVQLNNQLRSLGLYAAPTIGDGNCLFRALSDQHYGSPSRHVEVRREICDFIEAHPERYEGFVDVDEFGESGVRKEKGSGLSAYVAGMRQNATYGGHMELSAFAHLTKRNIKVVQPGLVYVIQCDPAQPKSPKPASKKAGDSPSKYTRSGSSRELDGDGDSPMSPGEGQDSTIYVAYHDWEHFSSVRNLRGPHTGIPQVCEMAPPPSAGSSSSASPPPEERLPPSKARKKERERKEKERKEAGRLKAKEKATPHTANGSVDKPKSRVKDSQASASSSAQQTTGFKLKIPPRSLPTPPTLYMTAATPISAGASPLSSLPPSPIEESDGFLDATTIPLPTSVSPSVATTPPVSQSPSPAPVSSSEQPTSDSEDASMGSPTVDLSATITLPKSNLSTTTSHASSDSSVYPTHMYSFASHPYAYAGYPTHLTQVTPAVTSASYHSSVVTGRPESSPSTSNSMSQPSQPLQILSQVNGASRPTSESSIGSSTVSPSTPVYFPTNASAVAIDPLSNLSHLTHLIPPPRIQRSPKRSFEESVSEEGSAESGISTSSAESKRSRIEDEDASEYRGRQGHRNEQMEDSPEPVENGVLPSLKEDEPESTDADDGHHSEEEGLMGKLQDSLPDAPASMLSARGSESPHQSNDEDDDDDDDYVDEEDANNDDDDDEDYLEPHVHSVVPPKMARNRHVGTMSERPLTRRQRKKLGLPKPRNIPMSGKGVGKIVIPGGKSTNSLSRDTSSTAEWTANGNGRVDVRGFRELKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCY6</accession>
    <name>A0ABQ8VCY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_406413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="230"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4488668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="438" mass="47013" checksum="658808EFCE6AC532" modified="2025-10-08" version="1">MQPQNSRGTSNDLYDHFRRNHQRSNSDPTPVRVIGASPPSPQNSAPEPPGVGHDESNSPRPSSAPSGPSGDSSLPNGTNPPSGPPGVPSPSNGASPSSNDSSRNRPSNVSYPVPPSPVVPWPFRPFPYHGNAPPPLPPPAPSFVVPTVPSPVHYHYVPSVPPNALPTPQLPLWPTPAVPSILSRPAMPAPGSAVMWESGTFPMSPLGGSVPLRVHPHILYNPMSPSLPVLQWDIVLRAEQARVLTGQALIKRPSLNDEAVVPAPTQSFGLSAGARNGQTDAKINKIWIESDTPLLAWWMQRWGPIIIEKSNITVRDVLDAVHTYLSIPLTNGDYKKAVEVQTPTDGVNHGNGMRLRSARRLRASNGCELRSVALRGRALEDGWSAQLMGADPGESSIYRRSDLLGTYRRFLGLRPIVFSDGSWKLLLGLGPGPVPKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDB1</accession>
    <name>A0ABQ8VDB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="395" mass="44097" checksum="6C23B7B4547A33BD" modified="2025-10-08" version="1">MASSSHNLSREAGLPGSFRWQDFTSSEDPENVQVLEQAQSSRWSLSTANTPLEGLFPSNARSFSRSKLVATSTSMSDLRAKPSYDESGRKKALLNKFRRHADPLIIPSAKKPHSLTLTVGIYGEKVGTKQFVSPYIESPICITPDSSSLTTSTSPIETSKSWKRRKNSLGKIVTYPTKILGKILPRRGDHSKESGAPPLSESSPTEEPQLSLRRAETTVMRPKRSSELQRPNEPVKRLSMASTQAIRAERFSFEHRSRQMDAKTPSDDNVQILRETTPPLPVLVRSMTQPGLQRRGKAIRAAPSNTPRPPFRRRSRSERRNPHSSRPTFPNSRDGLASESFLSLAEENSSETVATIANRIVAKELDQHQHDSWDFLDYYTQSGVLNAPFPVEFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDJ6</accession>
    <name>A0ABQ8VDJ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fruit-body specific protein a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_406326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046653549" description="Fruit-body specific protein a" evidence="1">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="23262" checksum="8B21819FD1FA8577" modified="2025-10-08" version="1">MRFFTLLTAAVFSVVVRADSNTAATAASAASVPSSSAVAVSASSFTNVTLQTTLSASLSEANHYGAPIPPWEVGSYPGWYYGTDPGAIIGWVLPWLLDDLLCAILDLLPGLHCPVPKPPPKNGWVQTFSNLDGATQADDYLTYGLVDTIEDCEAMCLNVQGCNFINTYHDVNGKNGSPQLTCSLFSLCHDASDADNKGGQTQPDGSVDYITDSNGFCLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE35</accession>
    <name>A0ABQ8VE35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HPP family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_715714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="2">
        <location>
            <begin position="21"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="197" mass="21544" checksum="3645C4FDF18724EB" modified="2025-10-08" version="1" fragment="single">LARLPRWISHWLGYRTSPAPKRPDYIIWIWSFIGAFGGLSILQAIFGQSHYFIQRNAPSIVASYGASAVLCYGAIEAPLAQPRALMGGHFISALTGVCITKLFGLLPTEQRLDQLRWLAGSLSSATAIVLMQMTSTTHPPAGATALIAAVDPEIYVMGWYYLPVVLLSSTIVLVSALIVNNIQRRYPVFWFAPSPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE51</accession>
    <name>A0ABQ8VE51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_834115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="438"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="59250" checksum="D4C794E0C4F892A3" modified="2025-10-08" version="1">MDDNSTDSANSTSPVWPRSVLVVGGGPAGLVTLRNLVERSKGQFDRVLLVERRDDIGGVWYQDEPIIPSANPTTAMNKPQWPSPAYPGLVGNVIPRFLAFSEAPFPESPNHPHQPFPTLTETYQYLRDFAEPYIEQGNIQLNTEVMRIEELPDKQGWKVRVRDWSMCDDNDGMPLETEEIWDAVAVCAGYYDKPNWPDTEGLNQVRKRGLALHAKWWNGPDGYEGKKAIIIGNANSSNDIASQLAPVAQTPVYRSTRRPAAPWFPSLADSRIKNVSAIKKYILQPTEETDDGTTPEKVTVILQDGSEIKDIDVVILGTGYCPHPEFVHVLPIPADGTTNASEIHNKTVSSTVPIMSYTTPVLPQFRRIPFLHRHILYAYNPSLAFIGAILAMTPFIVADVASTWLTLAWLGEVSYPNSIDERMAFDRERIAQVAKMLEVPDTVPENEGAGDSKESSPDPPSSFVTYGFLGPGDTGNGGKGGEAEYANNLRDDIVRARPDLDAVLPTWDEEAIKARTEMYPTKYEALKWAQMHCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF44</accession>
    <name>A0ABQ8VF44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="29"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="19735" checksum="C39A3341072FDFB2" modified="2025-10-08" version="1">MSNIIIRLYRCVATKIFDVQYSIQGYHEDYRDTKELEKHGTAATQCAHLIPESTYFRLSKDKKTAPVLAVLERFGYNIDSLNGPKIHSLHNVMSLIPSVHDFFDQLLWFEATIQHFSLSMSCAKVAHLSGAGEYIDRVQKYFDRLEVLAEDGGSSDVIFHALHHLAWVHVVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFS7</accession>
    <name>A0ABQ8VFS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="35486" checksum="D2B86C88E1282AF3" modified="2025-10-08" version="1">MLHGWDWAKKDHSTKGFKIHDGFDFVTAANEQIIWEGYDGNIGLGPRQGDLQTGTSRNFLASLTTTRQIIDSSIFIIRLVHPDDLDNAPLDCNLFNIISFGPGFPFQAPVSPDAYFSSPIPTISKDIAGAARPEKWRVKLLRIGICSVDRIDILMDTGTPMTVLPDYVVAKIQSDENWLGSSRQTQLDLLMNDKTYTRLAHKKIRFEFKGEGRHPVGVTVSAKSFMAWYSKVEAGDNPKLHLCSIKGAQNQDEFALGQNWYWAAIVKHVSPREKRKFPFVQVMSNGYFFDDDTNKTVRPTDMILKPLPPRLGPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGB1</accession>
    <name>A0ABQ8VGB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_835423</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="579"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4489244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="624" mass="70195" checksum="8BF2DAE35E980A62" modified="2025-10-08" version="1">MPRENSFSDSDGRSLTPDLDEEVSGGGIPPSSPTYSIPRDQLLAEPSFSSAPKESTEASAHSASSIRKKDATGPSTASFPMATRPELGPRDRFRSSVRKVMAMRRSTTLLQNNNIGAEPGVDPRRATADLQYGGIKQDCVIELVDYSSTSISYGRMTNKELVSMLGDKNASARQGWAKVRWINIGGLSWDVIKAVSLKYDIHPLALEDVFHTRSQTRSKADYYNKHLFLRILCHELGDPDAEPKTVESAALGSTLTDAPRSSSPLPFEDGEGYEMLEKNDKAWFGNSFGSRKSSTLRHRGGIKKREKDLEEGSLKKAPSLFSLTQNTETRQQRREEEVSIAALKKGARVTVDVSPMHIFLFRDGTVISMHPNSDLSLTQPITRRLQQRDTMLRTSADPSLLVQSLLDLIVDKALEVIDEYHLKIKKFERQVLLKPEVTTVRNLHILSGDLILHKRTLEPIKTVVYGLRRYDLDRAAALVDPSVAGNKDIKVVGFMSHKSKIYLADVYDHMEYILTSIEMFAGITENLINYTFNMSSYEMNEVMRRLTLATIVFLPLTLLTGYFGMNFEAMWSVQENSDVLFWEIAIPVMLVVIPMFLMPDLKRMLHYIQKRMVSQKALKSYKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGK1</accession>
    <name>A0ABQ8VGK1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nop52-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_957803</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010301">
        <property type="entry name" value="RRP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026">
        <property type="entry name" value="NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05997">
        <property type="entry name" value="Nop52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4485169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="326" mass="37224" checksum="39AAC15F7FCE9FC1" modified="2025-10-08" version="1">MPTKSSSSSSVPPLNKYLASTEKKTRDKAIKTLSVFLSDETRDELPKSEMTRLWKGIFYCFWMSDKPLVQQALASELAELVLTTTNSSSKLSFLNGFWETMVREWNGIDRLRLDKYLMLVRRFVNVSFRVLIRQDWDFKICQEYNTILSHQDGPLCASDGRVPVGLVYHIADVYLEELEKALRSSTRDTIKPVPLALILSPFFNLAAQTPLGTIYQHLQSSLFDPLLLSCSSSKVTSEDENDGETRARKRRRVNGGSSDMYPSMISNACLDNASIEVKLPVSDLRKKILRRLFEVASQAETRDANRRKIYALWKAENDDEDNTDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHE6</accession>
    <name>A0ABQ8VHE6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_829861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF6">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="419" mass="46225" checksum="277AFB2769572BA1" modified="2025-10-08" version="1">MANLSKINVLMCGTGEYTTGWTGSGASKSDKKIGVVGLTLFDLRRLGKVDKLGMAGVNGGKFPAIREHLDKNIGGVYKDMDLTFDEYPKGGKIDPEAYKEAIDDMSKGDAVIIFTPDPTHYAITMYAIERGIHVLVTKPAVQLLSHHNELIAAAKKYGVVCMVEHHKRFDPAYSDARAKAEGLGEFNFFSAWMSQPKSQLETFRAWAGKDSDISYYLSSHHIDICCWMLQDKAIPTRVVASAATGIATSEPYNCVPQTEDTITLLVDWESTTSSKHKGTGVYTASWTAPLKAGVHSAQHWYYMGEKGDITVDQAHRGYDVTVDDTGKTWYNPFYMKYSPSESGHFDGQRGYGYVSIEKFIDAARSVNAGHTKAEDYDKHGLPTIANTVLTTAILHAGRISLDEKRPVGIKKNGDEWVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHM5</accession>
    <name>A0ABQ8VHM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_829001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031101">
        <property type="entry name" value="Ctr9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027:SF2">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="554"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="909"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="976"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="976"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1015"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1029"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1092" mass="123139" checksum="38948FBC20F95990" modified="2025-10-08" version="1">MDIDDEFASTGRSIDIELGSQEVITIDLDNLDSNPEDVLELLRDGQCKVWVWTKLAGEYWRRGYCEAAEQIANNAIASFKMNGNAASLSPIYSLLANIQIDHSRRAPKLILPNAREDIMTNQKSKEEYHREAASLINAASSSASEASQSGEPAVSMELAFLTRGIQQLATRHMDEALRSFEDVLATKPTNLVALLGKGRILYMRRNYPQALQIFQQVLRYNPHCHPDPRIGIGLCFWAMNNQAKAKAAWERSLELNPSDWTAQLLLGLESVNSSKDGHLKEEERARLFLSGTKLIEKAFNANQKNASAANALCEIFVQKGAFKRALKLAERTIQFADTLPLLTEGYIRAGRVSHAEGNFLAATRYYSSATEGQPKHVLAAIGLAQMQMNNDEPGGAINTLDNLLQAPNPQKSLEATVMLASLRGSPRPGISSNEMVQERARARELFDRISKTLEIEDGKVNGSGLSKASRTISEDMNMHLEIARLWQDENLDRSSKALQEALQISQLSGITEPRLLNNLGALHHLDSNYSQALGFYETALMESMSSENAEIISTSILYNLARVYEDQEEVEKATDAYEKLLSRHPEYVDAKIRQAQLLHNIKRNSEAHDLIKESLASQSSNLNLRAFYTYFLVQTNLTKNAKDFVFTTLKDFDKHDIYSLCAAGWIHYNQARESRDTSSKGTEERRRGFQRSTEFYEKALQLDPFCAFAAQGLAIVTAEDALGTLSGVSLSAGDEAQRRIQSTRDALDVFAKVRESINDGSVYLNMGHCYYARDEFDRAIESYETASVRFYRGQNVPVLLCLCRSWYAKAMKDQSYPAIKTALKYAQTAIHIQPNDKAILYNIAMIQQKSAEMLFSLPPAKRTLKDLQRVIEMAQHAHKLFGALASDKSQQVPYSRDIADQRRKYGENMLRKKDDHISSQTKHEGETQARLDSARQIRFEERQRQEAVEKEKMEALRKEAEKLAQERRLAREQALEWTREARMNESDEEKEKRPKKAKKSKGDGTGSGDEGDAPKKKRRGKIRKANGDPTEEGEEPAAAFSDEDDAERPTKKRTKKRVLSEDDEREVQTGPQRKRQFKSREVLSDTDDEMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI53</accession>
    <name>A0ABQ8VI53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_767482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="471" mass="53450" checksum="24B54D3525199442" modified="2025-10-08" version="1">MVSFKFLDLPLDLLPVIFNQLSLPRHLRNICLVNKTFQLFATPKLYEQICIHSWHKRGKERVILLFLTLSRYHHLAKHVRRLELRDFPKALTNSDGLDIVETVVHGLRNCANLQSCTWTRDGSLDSSILEALQSCHNLQTLEINGHAEGSYDPKLLIRFGGLHSLSLIMPSSSVISVLRPWLQGLRTPLRSLTIVCKTSPILTNAKLELLAPYLSRLEHFHLTGCSRVTQDGIESVLSANEDGIVSLDLEGLSPKFDLFQFTLYCNKTNSLRRLRSITLTVNQQTSLNTWMNEVAALLPATVPLETFQIYSSGAFIEQSPATEQLWSHLLNAHQGHLTRFSIHRMLISLNTIEDVCRRCTKLEQLFVVIEPSSLENLSSCLSLAPNLRVIHINYPLETTQMGNIHILPESDAQKIVDRCGPNVVQFGCNTRVWQVGREAFLDQHDDPVVIKRRVMRYQGLDIPEAFLVVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIK8</accession>
    <name>A0ABQ8VIK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="532" mass="59223" checksum="3790CE040CD83195" modified="2025-10-08" version="1">MSVRFSLAKATSFRPWSKKTSTESDIFTGHHMHADTRPASITRLHSSPERLRADSSGSGYLDRVPENGSVEFDGRDEEENINEIDEEFESQGLYRGSYRRLLVLYAFVPLSFVAFFVLLALLPIWVYPLQITPEYPSVLPFPFPELFVSAGLWCLSYLLRTPIYSLSVLICTSCWLSHEGFPTVLSTVAHAILSLFFRLLAIPILVIPHYLVYDNPTWRDPAFRRVWWVSLGWAAVEGIVAIKQGYANIALYRDVLVHDVHEDERIIEIEDRATKLGRIYGATDQITYTAEPSLAPLGVGSSERTSPTQSVPLRGLATTAISDADASSNSERVPLLLQRESRASNIDLETSLELQVEDDIDQLMAVRARDELGKYYGIPFIRIPAFISCLQRANALLFSLGVTLILSSAYLRSTISSMSWYSMNTGPDVLSSDKYLALYVITSDSPSIPSLETFISSAWPWSTIQLLPATFKKSNHVLTIGVPVVTILQIVLSLLHSHLVLPKAGVHTVVYIGSLVSLGVFFIGLSVWDALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIP2</accession>
    <name>A0ABQ8VIP2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_339075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="30810" checksum="111E224A2592B354" modified="2025-10-08" version="1">MVMITYTPSYPRPGYRKRGIVCTALIAVLASTMLEATSAFPVPLPPMSEHQKFIGSDTNAINTTSISGYEHYNVNYGKYDPASGTQELESRGIKINKVTSRIEMKLKNPKRKTMGFAYLDVKLLALPPESNDMIFLDGIFDLGHLVLPAWNLHWSGDFMYLLKYSDLPDQNPENYWICVVTLEEDAPLNIRPYWNGREKWNRKGKGPHMPKTYATFWDGNPNFPNVVVLEFPKKPFVESWVMDAECYADHKLLHKVDWQGWQQYPPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIS8</accession>
    <name>A0ABQ8VIS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_829842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1107" mass="121784" checksum="CD341D144CEB81A3" modified="2025-10-08" version="1">MATVQPPTDGPLITDNDHELEPPKSESQSSPDASEDVNEEPAQVYSQPSPSLRIYSRPQILALSKSPLVCVPPNMPELRDWFGAENEQNLSRKESEPLTPNSGRERRFRRDGEENDQPRPSFRSSMSQPSQMGNFKHQSMRTNDRDLEREGQERLRNLSEKFDRDRLNGPLMNIRTEKRNIAATSSNRIPSQSQGTIAARRAETRETAKKKVGESNEDWRRGVETRRSERNDRGDRDERPRSRSRHRRESSLTKRDREGKEREKERDDYKRERVDRERDDDDESRRWRDDGRRDERLASRRERERGPNNNGKDKDPNAGNPNDRRWTVVEERDARSKRNTGRDKRSFPEEARADDRRGDREKEKEPAWMDTYVPSSSTGGILGSKGNEGELDGIQAWKKNLKEKEQKAKTAPVASGVDSSNDSPTMTTSEEPMDEIQRFKKMMEVAQKQSSDPPPMMVGPILGFTDTPKLSSTRDNDNVSIPKLPDANPDGEAITVSASSKLDIASVPDPSRSLLSLLNSNHDVPLSADTDLTAPKVHSRLPLADSPVDRLNSDTSFNPPQGSRLLALSNRAPAKPVAPSSQYMSSAIPNGGPTSASTIPKPQIPPPLTGFVNLSNPLTLATESSKVAPRTPSSFSPFEEQRELGDTLRRQVGERSPFITDSAGTWPDPSPLDSTNAGHAMGKGSRFAKFFDGKGKETLITAPNIPKAPTPVGFVSSSPGPHVRPDSGFGNISNSSLEQHRTVDELFAKLNMNPMQGQRVVSGPNTASLNHVPFSQQAQSQLHSLQQQHQQMLQNQLHNAARLEPLYESRNFVPDNLVPGLRSAPPPRNRDNGGMYAADPLDDALLLHAQQRLPVQQQRGVEQLFGGSIPASFAQQQQLARNAGIPVQAPQFRGGPSPVSASQNMLHTAQQQRMPPGLANLGARPPHDPGQFIPGPLHNGLHVNVPPQQQQQSFNNFHPAGGFGGPQGPLRPPVHQLQNTINHHQLAGLGHPGTLDSRNANQHAQLLALGLGGAGGKFSPKSNACHASTSAAAAAPSANVAPSSFASPSSTGSPGTYGPNNQCSGPYGPPYGCSPRVTLIFLHLDFLSTMYHFPVRFSVQYNTLNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIW2</accession>
    <name>A0ABQ8VIW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_274116</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="986"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1096"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="663"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="872"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1182"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="874"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="920"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="953"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1195"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4495571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1296" mass="143913" checksum="DCAF10B189102C8C" modified="2025-10-08" version="1">MSGSTQRPSEICSSTSSSFEGQASLKTANSRLVRPYARESLDTTSSVPGRAVKRDTGVLSTEMFTEGSRGTTIRTKAPTNDNLDHGEGGRGATIRRHSVNMGKSIRRRFKSVTGVLTRRSISVSYPANRTMDTGFPFEPSELKKKPRGSMTLDSKTVMRPLQSSQNGLLRTTLNSPSIHPLELPESLSETETQPTEIAFISPVQSPSPHAAAIDQFIPEDQILSPIIPFSDSILTESLIDFVVPQFLQQGTPLLKISKKRHKPIQFVFRLDADQGRIIWESKVQKFIAVENIKEIRTGQAALHHITQLQCTPVEDYLPRWLTLIYLGPSPSKARSKPNLSPLPLGSPKSNYSVHTYKTLHLVASSDLVIQLWERTLRSMVALRVSLTSGLGFGGGMNSDRIMEETRQALWERSFWTAAGENMRSRFGSNADWSAGEGDESLELSGAHEGQRLTFNEMRALCERLNVRMSEKEVRRLFNNADTYRQGSLDFEGFRRFGKLLKARPELDRLFKSLVQSNVIADAVDDGFFHRQSSSGKDCSNMPFNIFRSFMREKQKSALSEAELKDIFDRYSVEVAGTTIDDQGSPYPALPYTNHTLGISTSSLEALPPSISSSSLNVREWEADVSYIPPSALFAASSPPTTRVITLETFTSFLLSSDNPACLEPRTNDEAGPSTHNHGFSHHHTRHVTTFHRLSETSHDMTRPLSDYYISSSHNTYLIGHQLYGESTVEGYVRAFLGGCRCVELDIFDTDTGPQIFHGKTLTSKVSLREVCEAIMTYGFVASQYPLIISAEIHCGLVGQAQLVGIMKDVFKDRLVRRDENGAIVGMSEATQSLDRTSEVLLSASTIEKLPSPEELKGRILVKAKKLHSIDYIDSPPLSQTSSTSSRNTLQLGHPFDGITSSPSDTDAMFDLQNLSMSMRRSSEGTNRDDVDSDMLHKVRGRGKPDSSPPPSSYSPRRPIKKPLVSGHSSTSSVASSKTRMRMSPDLLSLLVYTVGVKYRGINKKEVYRSEEMFSLSENMANKMLKVGMIDLIKHTRDHLVRIYPKGTRVRSTNYQPHRYWSAGAQLVAINWQTVDLGYMINHAMFQRNGGCGYLLKPLPLRMPHKGLLSKQTQHYLDLTIISAQHLPAPKDASGKDVSETSPVNPYVQVTIHVPDWPTPPSVSANSIASGLVSANDAVSAVLSQGSGPPSPSSGYFPTNPRSPRSTSYCTSVVKNNGFNPVWEENMRIPFTCVGDMKDLIYVSFAVRHTEREDVEPLAQFFASLGCLQHGYRHLPLHDSQMSQYLFSTLFVRIDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ15</accession>
    <name>A0ABQ8VJ15_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rRNA-processing protein FYV7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_762539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21787" checksum="46B883DDDED0F5C2" modified="2025-10-08" version="1">MVVSAAELHKKKKPPSFNHYPEAKAKSLKKAWVEKTKIKSKWRAERRKMGLPSRSLPSRTDDARKEEQNEVADKEVEDNKESESADETVTTRELPMKFQRGPPRPNLAFASQSKQLKEQPKEHDAPDLRELTRKAYSRETLHTYKSDPLNRRGANRGRGHSRGGIRGRGQPNMKLRMGAMLEKIKRDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJJ2</accession>
    <name>A0ABQ8VJJ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_976804</name>
        <name evidence="2" type="ORF">C8R41DRAFT_980254</name>
        <name evidence="1" type="ORF">C8R41DRAFT_985539</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000148">
        <property type="protein sequence ID" value="KAJ4464045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="187" mass="21171" checksum="512EDCF64F0C30CE" modified="2025-10-08" version="1">MATTPDTPLSLTDTRAVALAVYEHQLRVASLVELTPQEEPSLQEHLDALIERKRRERACSSESIAVQTSNSVSILVVDENRGIFCGNRAPRNSTIAELTGFIEELIKSQNDIQDQFVASEWQRKCTENDVEIHYEAALATLKQNQQLWEVAIDAWRDMLAMQEKLARVEQQLDDIRKSISASIHDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKS0</accession>
    <name>A0ABQ8VKS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vitamin B6 photo-protection and homoeostasis-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_917957</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF31">
        <property type="entry name" value="RUS FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="7">
        <location>
            <begin position="6"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4496982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="50528" checksum="A6B4EE6A8917247B" modified="2025-10-08" version="1">MGDNTSRASFLSFVAKVFLPAGYPRSVSPDYLRYQMLNAAQAFCSSLATLLSLRATLEGYGVGNASASSTNALLLTIVQNISNRLTIIIAAFFFGSSLFPEAKTYHFLADLLSDVTIVIDTLSPLLASLYEAHVPNFITALPFLPPTVPLRVYTLCFSASIRALCSVTASGSKTAFKMHFATPLEGTGDVGDLNAKNSSKVTVVALLGMLIGTMTMPYLTTPWSTYTVLFFMVFFHLLINYIAVRGVIFRSLNRQRACLAWMAFKSKCDSINTPTYLASLEHILISSDTILDLPSGTAIGRCSMGSSFRACNPDPDVMEIFQQKHYVICLDKKSSLCFGTKPHFHILLKDGYNSADQLHAWILACEVTRLFAFMKTKKIGLKTLMQEALTTFNEDYLSFLEDLHKNGWITVTVTADESTIKKNSEYQPPPLLPGSQIISFTSGATRNVMISFSSTQYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKX4</accession>
    <name>A0ABQ8VKX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YT521-B-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_824586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057720">
        <property type="entry name" value="RRM_YTH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25701">
        <property type="entry name" value="RRM_YTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="340"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="YTH" evidence="4">
        <location>
            <begin position="516"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="YTH" evidence="4">
        <location>
            <begin position="676"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="582"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="823"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="660"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="824"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="880" mass="96336" checksum="347689E37D3CF415" modified="2025-10-08" version="1">MPGDASSRGMSDHVGGSNRRSSSYSQSNQPRRPPHNTTAHSQFSLENPPGSTHGPSPHYPPPSQYGQRSGFFGQYTMSPQPPMAMAPSNPTYGYPHGFQNLPENAMIPQNIHASYQSMLPPAPVYSYQRHGSEGTSTGFSSQPMFSHPSQGNSPSPPMSSRSTSQNTPPPYPSHGQFHSLRYPSSMSPSPYPYSHHSYSSSPVYQSQYAPAPYPQHFTSPAEIEGQGTWWYLPHAAPNAPSYPGHYPMNYSPVHQELENTYTATPGASVPASYPISPIRSPASINSARKPPSSLAASGEETPANPSPGPIASSSKSVSGERPSAARRPYHPNPPSYRSEWVMWAGNVPSDATHDELWRFFSQSDDTASSSGVISIFLISRSSCAFVNYENEAKLHAAIAKFNGVPLRSHDPRCPRLVCRVRKVDDDLKAGVGGQRGVGMHAKWLRDQREMAKGKKKATDLSDHSDLDDSNSSIAALSASVSSDDDTRPPFVKGTHSNSSGSYASTNSSLLTRYFPKRYFILKSLSQYDLDLSVRENLWATQKHNEGILDQAYRTSNEVYLIFGVNKSGEFYGYAKMAGPVRKGEQRVPWASRPDSSASSRSSLSPITSRAPISDTIPEEPNSPSSQENPTSPPARNFFPARENRLVEASPDPVSPPSVPPQQSSQTSVASAPAELGTLHHRITMSTPSVKLSLDNRWKPKLHSAQAQFHSASQEDFELDESAPFRAMRSESSGNRLDEDLSRIRLNSVEEVEERAEDLEKAMDGKPETWGEPFKVEWLCTDRLPFFRTRHLRNPWNHDREVKVSRDGTEIEPSVGEQLLQEWSKLVEDGSHQDSDPAPSNAASVAKPASKRSGSSSKLAPANPGPKGAKDREPGLSTSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKY2</accession>
    <name>A0ABQ8VKY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_244241</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATP phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13592">
        <property type="entry name" value="PBP2_HisGL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP-PRT_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF8">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="10">
        <location>
            <begin position="60"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="11">
        <location>
            <begin position="229"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4497038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="304" mass="32851" checksum="2A080841828EEA9C" modified="2025-10-08" version="1">MNADSLDGRLLFAIPKKGRLYEKCLSILAAIGADIQFRRHARLDVCLVLNHPIALVFLPASDIPSFVGKGNVDLGITGHDVIVESQMHEHVTEELRLGFGKCALQVQVPEAGSITTVEDLAGKRVVTSFEVLSGDYFGKLDDQLRLSGDKRTKIEYVGGSVEAACALGLADGIVDLVESGDTMRAAGLHAIATVLETEAVLIKSRVPKHEAHSDLITLITNRIKGVVAASKYAICQYNIARDRLPSAIAITPGRRAPTISPLETDNWVAVSSMVEKKRLAQIMDDLVTTGAEDILIFNLDNCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL13</accession>
    <name>A0ABQ8VL13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_826232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="46232" checksum="506618850B5F649A" modified="2025-10-08" version="1">MSEPLDQQLPLYSPSRSPPSYSPHSRDGEETLAQTCRFHSSSHATGTFTKHHGDVTVVLSEQDEDVDVPSYGRHGLLAGSIILDSSLKIEDIVAVVLKVEGRIKLNISGANAASKTVKTVDEQYELWSCQTPNSSISSTCPRLIPFSTILPPTFKDGNHEYPLPPSYEVNFTGIPGLYAKCTYAIRAIVKTHGSFWDHKQTVSTPFIYRPRKRPPQPTVASEFFSSIKVSPEEWFQTTSVLQARPSTKLESINVSIFLPAVRSFGLRDTIPYHIQLTGPISSLKKFYSCVQYEPEPSSPRSQSTLTMSVSLCRQVRVEVKGQAVWKSSIIGSGTLTALPPSVELDPRLSHSAHEMALDWEGEIRCRDDIRVGHFDAGKIAMSDFLVFSVVPKPTMGAFNSLRMIVPILLVTDTWVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL42</accession>
    <name>A0ABQ8VL42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_823328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="94" mass="10617" checksum="E9BEBB3CAD73767E" modified="2025-10-08" version="1">MSSPDLPDTPQLVFQLLAGPEHRIDYVRSSLTIPEITFDLFKQAVLPSVEESFIGKAHQKLRERGILIDEGWKETNFGVGEQEEETKVKLSASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLI4</accession>
    <name>A0ABQ8VLI4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_759677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46506">
        <property type="entry name" value="OS05G0143600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="44"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="583" mass="61530" checksum="6324CC947A145403" modified="2025-10-08" version="1">MSSLENFPQLPASVGGQPIPDFLKFKVRGPVTRKPVSDKFNFAITASPQFGTQEGSTFDEGKLWHPIQSLEFTSNNESTGGGLMSFRGNYQARSTRLVGKEASSKSVVKLVSGEYVKGISGTADHYITGLTIHTSKRDVPVVTGSGGTDFQFVVPTDHQVVAFHGTENGNRVASLGVLHQRRLETISDTSALAADDPTPVLNASLSSQWLDANTQNAWANNDMSTVENLKIQASQDLLPIYSNIATNGDSAWTEVEGDDGEIYYLSWTTNGVIWSYTPTASNSVNKTSGTTTDTTDTIVSIGSYSTTANFLGISMYTWSNIPTTVVSAVLALGFAYLVRPIIQTGLEIGLAAAANLLAEGLAAAGLESAAVLVPTSVATIGGVVIAGVLGVALALGCIALSSVIFKQYFLVINIYNFDTAHQWATVQHYQDNSVVSNGSWTDQTLAKFVLSGNKVAPPGFDPVTTLDNVVTYLNANFQNDSTFLEGLGEAIVLNRDDAAAALAIKYVVNRASDNQIGAVGISGSGATYDLGNYYTIGTWNTSTSCQTTAGGLTVNCFTPALGGASNDTYTYEVNIGLPPSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMG9</accession>
    <name>A0ABQ8VMG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_737266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="70" mass="8171" checksum="44ABF5D2FFE14B21" modified="2025-10-08" version="1" fragment="single">FWDDNLTNEEMDLICGSYEVATGSISNQGQQQTAMKSWWPRSGSWRSCGLNCGYWSRDAEDWFQNRLDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMU3</accession>
    <name>A0ABQ8VMU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_183189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="355"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="706" mass="79583" checksum="65CCBAEE1C6A3A91" modified="2025-10-08" version="1">MYAPHCISKSIDVSIEFLLPSLPSLPTTISRSMSEFVSVGHPRMLRSVKGRSRTQPSNSNPELSLISSRSSNGAQIFMKMSTLREVTEEPQQRRFDAEQQSTIGSLSVSKSTATLSPQERKEQKKKRKEKYDRPLPPTPPPSESIFSPESGFELVALDDNVSVSSSPTLTHIASTSTFSSSVDTLKSSKKKYQPEMIYFHLHRLVEREISKVADGSTESDSTLSHPPPSELSVGAVPGVVQSRKYRIKLAHMLSNLATPEVSSAYENKIYDAITKDEPQVARLIKIILNSEEEKTSAMALKGQEADLFMDALEDIMRDTSFLRESEQLDARRFLISLSKISTNLPQYMFIDGVASVKDKNSYGGTFGDVYRSTYKGKPVALKRLRHFQLEESHRIYQRFCKEALIWQRLYHKFILPFLGIDAENFPRQPCMVSPWMANGTITQFLKHNPKANMDKLLFEISQGIHYLHSQNIVHGDIKGGNILIDESGQPRLADFGLTIFADGTRHNTTDQGGTLRWMAPELLYPIPGIECYKRTTASDVYAYGCLCIEVYTGRVPFADVRSEIMVLEKVLKGERPERPLGTNAMTDELWNLINACWKHDRAARPKSGLVVDHLKHILRRSATDPAVLPFMDPLPPPTAYSHTSPPTARYFTPFSQTLTMYGAPTRTRPLEEQAAVLRSLKRIRRHADPGRMYHELKLTYVNLVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNY8</accession>
    <name>A0ABQ8VNY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA recognition motif 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_790810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007201">
        <property type="entry name" value="Mei2-like_Rrm_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04059">
        <property type="entry name" value="RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Mei2-like C-terminal RNA recognition motif" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="188" mass="22148" checksum="330DBC6FFB1C8036" modified="2025-10-08" version="1">MIKNIPNKMTDKDLMHYIAKVCPRRIDFLYLRMDFKNGCNVGYAFVNFISVEDLVLFAKSRLGQKWNMFSSEKVLQMSYANYQGKEALVEKFKNSCIMDEREAWRPKIFYSDPGPEQGLPEPFPSATHQRRKERSSHNRGDLFVPGNCSLPTQNLLNAPFGPRRFDSSPHRRERERNHRRQRTTTTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPL3</accession>
    <name>A0ABQ8VPL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_759643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF33">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="39672" checksum="53B9AFEAC77B2C73" modified="2025-10-08" version="1">MGVITDETLSKYHERVEGKTVIITGAGASIGRATAILFASYGAKVVVADKSLSGVEVTVSEIRSIKGQVVGCVCDVTIWEDLVAMYDLAIQEFGSVDTVVANAGVGEIGGRMMYNPSEGRPVKPLTTTIDVNLTGVLYTVHLAQHYLQLNRPMQDMSPESLSLKSVVLLGSLASWTALTKAPMYTASKHAVLGLMRSLDASFVSRGLRITSIHPFFAATSMVPNVIRLQLAGIPLAPVPRIARTILYAATQSDPACSGAAFWVPDGGGLVLMVSKEDFKPGVYEYIDRSSNATSVYVFILSTSIQQLPYFFNFRGLVGPKYYMRRIYTITQLLWRELVIVGGFTTVVGYSIWARVFHWLCHIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPL5</accession>
    <name>A0ABQ8VPL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_757482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2381"/>
            <end position="2436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2381"/>
            <end position="2409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2416"/>
            <end position="2436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2436" mass="253825" checksum="4D21DD506E60D2CB" modified="2025-10-08" version="1">MRLSINYFAVGHVRPPAGSRFSENEIARTTAAGVSGELREGAADQDARVTAAAPAGPQSHVPFYKKRKFIISQAILIPLGIVLLFVLLFPVVTAIVQDVLNRSILGISVATISNPANSSFQLALQGSVSHTGIISARIHFTQPVTVQWVQPNGSQLTIGNMDLDDISASHKRATVDQNTTFHITDQSVFGQFAAQMITANNFTWRLLSNNLHVQAAKFPVSKGIKFDKTLTLNGFDSFNGNVNLTNLLLPSDDPAGGINFEATTTLNNPRQVDFYLLSSMRHLFSFYFCSPFSLNLGTVVFDLSYKDVYLGTGSGSNTVIIGAAKNDITLSGTLVPQSGDNNLTVVSELFTNYLNGDSSDVIATGKSTLQTDGTAISWLSQGLEALQLHVPFVSLSGAISPIKSIDIGDLALEFAEETPWAPSAQSQTVQASLQLPFGFSVAISEIQNSFNLTNGDQVIAGLSTPEGASMSSIEVVNSTFTAGTINITIDNTNLSVPDPEHPHFSEFNANITSLSSVDFQLVGQSRAIANLSIGQITLDPIKFNVPSSLNGLQGLNGLTAIHAVDVVGGTTEGITLNINVSIVNPSNLNLSTGDLTMQLTRDGALLGTALLPNLNLTMGNNSILAQSTFDSNNNPQAQETLDQFVGRQDVQLSIAGFNSSTAIASLTQAFETLEIGLTLPALATNLLNTASLKVLSTTGLTNNISDVTVSLANPFTAALDVTRIQSIVSAFGITLGTIQTSTNFSSAGKSNTTSPTLPLNMNLDPSALFTVTRALAVNAGEDIAPLDGIVLLGGYEYLMTTGPAVSTESDASLYKNFTLPGFVQTAFKQLKSDVNLTVDVTIGEYNAVLNYFQSSLPTETDGSLDFILPILAKPIVQKIVGGAGLGIDAVLISDPEQSSFNTALNGSINNAGPFDATIAFSQGLTVEWSGKILGTLQMDNITVVGGQGAQLNANSVFQVVDVDALTDFTKTLLTEESFEWVISGDNLTVTALGIEVTGISLMSKSVTLKGFNGLRGGVQIQSFDLPANDPAGGIHLTLNASVTNPSQVGIELSSLRFSSYVDGQLIAPVSSSGAVNLNPESTSNLALVGRLIPQTSSEGLAAVSQVFNNFIHGLDSELMVNGASAGPSDVSWLNEAITALQVETSLPNLGVLNIIQSINLKELDLQFSEDTAYAPATSSNSTTATFTIPFDFPIDIVALQQDINVAAEGQVFAQLFIPKGPSQTDVNARIISLAFGDVPFTVVDGTNNVFNEFLAATTVGTSVTMGLSGSASADASTAVGTLSLTNISFSVDTTIAGLQGLDTEPVTVNYLDVFHGFPDYLLIKVSSPLTNPSNLTIGAGDVSFGLKFAEQAIGLAVLDNLVIVPGTTIYAIDVQFSPQGDAVPAGQTLLENYLQGVNSNTSIVGSTSSTPIQSLQEAMSEISLSPVTIPALNQSLISSASLTFPTDIVSTGIAEATFSLANPFTASINLLTVDASATYQNITLGTISVGETSNPIHADGHSNITSPSLPFNFNLDPVSIVELLQAGASANGVNLGPLIDIFEFIIDNPNFNPPVNSTVDTRSPTCVSGNQFDVDTAILDSLKNLKIDLAVQSSVKLDDYATNLAFAQHGVDAITDSTALYLIGAVAGPVAQQFVDNAELSFNQANISDISNEGFSLTLKGSLTNTGPLDASITFTEPLEVTWEGRQIATISLPPICAAANAGVPDYETDATLSITDLDQFTTFATFLLHNPSFSWTISSSKVQLVALGTIFDNVSLTKNVSFNAFNGLSGVTISNFQLPSDSSEGGITIDLDAQIPSPAQLGLDLGTVTFDSFYDNVLVGPLVGEDLVLSADATTTTHLSGRIIPQSGSDLNIIGQLFSNYLAGDNLTLVAKGVSVQPPGSSSTVSWLSIAFATLALDVILPGEKLDVIQSITLADLAVMLNDDSEAYDPSTGSNFTSASYKNPFGFSLQVVQSATDIILSSNGVNIAELSLPTSDTVGGVSTGNVANLPISWENEPLKSLNDDAFNALFAAVTLSNSISLELDGSANVTAKTTIGDVPISRIPFNVTSSLSGINSFGGRATLSNVTVTGSGGTGGNEFINAPLTTTLENPSNISLDTIDIALPVYYEGSMVGRASINTLNLVPGTNSVPSEFHYEPANSNDSVAQSFIADFLTSNNSLPLSIKGDSASTPIDSLQEALSGLSLSASLPGDQTLIKDIMVTITLDSLTTNEVTVNVDIFNPTDAELQVLAIQSTGSIDGTVYAQFSTTFDSYLIPAGQTVNSGEIDHVLLTQGAIASLGIIGENLDVAAANTIQVGVGGYTLPWLKINQLDVPTTYTLDIAGLTLGQLKSQAEQNASSISSSAVGSKPTSASTSQNGFTSVSATVSLSSLASSTITSSITGDGTTAEATSNASSAGKEDSSTATSATANTPLMPASSASSDAAPTSATSVATLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQD5</accession>
    <name>A0ABQ8VQD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="664" mass="72560" checksum="690668E80A1D434D" modified="2025-10-08" version="1">MSSKSNEPETSAPKRYHCYCSTYCGGPDGLGRLISYSSFRLHLQKSTVQNDMANERPWIRKRVSSKLSTTTLEAHKHVLRTPFHLPRPQFRKPSQLILPLDDTHEVPPTASEIGNSGDDEGLGPQDGVNVQDNEEPEDEDVVDPGSLFEQHLSDNAPSGSLSQQSVHRDDEENRFQYEDDTQSPNFVPNIDDIRISYKFINELRSAKLDSPIEPLDDTLLQQILDPPQHLLEVENPDECLSLELYLATTHTSEETYTNACVAVTRRFPDCRLLSYYMVKKLVEKLSGVSPIVRDMCVNSCIGYTGPYASIEDCPHCGETRYKIQGKKKIARKQFTTLPLAPQLQALWRTTEGAASMQYRQNCTKAAFEELEHNNGVKVSAYKDFFDGTTLSNEQGIASSTKRSLEDDQETGSPIKKRFNFVSPLSMQGTAKTADLNVKTYASPTDTLLHSTSTHPDTISLQTGFCSNTGNFNESSNMDDISQNGDHNSSSSPLHAEQLVLDPSSSTLTSSDTSTILPSATQSTNTAPVDAGPSANRGAPPVIPAGIDNVGTSIDVDRSVPIVAADVSPDGHGVPGVPVGGSGAMLNAETQSNESKKNSKAKTRTTSTGNSTVRPNTSTGMKNLCMIEFKNKHGVKATRQAFEEHWSVLDETELKEASAAPALVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQH1</accession>
    <name>A0ABQ8VQH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_817226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005373">
        <property type="entry name" value="PHAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039156">
        <property type="entry name" value="PHAF1/BROMI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465:SF2">
        <property type="entry name" value="PHAGOSOME ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465">
        <property type="entry name" value="UPF0183 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03676">
        <property type="entry name" value="PHAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="376" mass="42601" checksum="E0D708BA84707659" modified="2025-10-08" version="1">MFPTLDVELRPGFGLGAFELGASLWNIINMIRQMQHLFPQVDIKYDPDASSTTPIILHLRPHLDLLFSGKNQRLRTICVRKLRDTSPPVTLHYKGSVLSSADEVLRRVGISRNFGPTYPGDDLRYPGVWFSFEEEGIGEGRKGNAHNEDRLQEVKRVLISQKEVDTEQGDALGEVAECPIMNSDIALAIVKVHDGVTLQFYPSNTASLHVRIGTTTAQDLAVSLGRPLRVHYKEDDRMTIHSSLQDESDTGYFYNYFQHGIDFYISGKSHVVKKIILQSNVPGSPLFQVYKRCNWEIEGKPEDDEDDTPPRKRFYDRFETISHFLSPREPPPSMLLDRTNDEEDITLPSATTRLYGYDGIILEVSEASQVISVTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQL1</accession>
    <name>A0ABQ8VQL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-dehydrosphinganine reductase</fullName>
            <ecNumber evidence="9">1.1.1.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_817341</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>sphinganine + NADP(+) = 3-oxosphinganine + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57817"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.102"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:22642"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.102" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4498680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="338" mass="37156" checksum="1983ECC61B807104" modified="2025-10-08" version="1">MLQLSDFQSAVLTSIFATLLVIWAMWPTKKWDPRGQFCYVTGGSSGLGLAVAKALTNKGAHVTIVARNEERLAKALAELEELRQNPNQVIRSYSYSLTDADSSKAALEVASKDHSGKHPDAVFMCAGAATPGFFVEEDANSMRKGMDNSYWIQAYTALAYTKAIVRDKTSGKLVFISSLLGYMSMLGYSTYSPGKYALRGLAETLRSELILYDCTVHIMFPGNIDTPGYAEENRTKPKVALEVDSSDKPTAPDVLATQLIYGVQRGDFHISPDMLSNIFRSSTIGATPHHNVLLDGLYAVAGWIGLPLWRQGVDSKVLKHRNEHEEYLAAKGFFKTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQZ3</accession>
    <name>A0ABQ8VQZ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_102452</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037381">
        <property type="entry name" value="RFWD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RFWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047">
        <property type="entry name" value="RFWD3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14634">
        <property type="entry name" value="zf-RING_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="195"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="35430" checksum="540741848B29C3D6" modified="2025-10-08" version="1">MLVVDVSSSCDICLEPFEWDFTQRSPHIIDCGHVFCAECLHQVFPTKCPLCRKLYLPSEIRKLHVECRSQADDDKEEVDLLKELITAYDSSEEDILRLRIRVDAWLSSRTLNEHSPLRRARDALEQYQQLKQKRFQDRRKIKTLERAARQWEKSVQDSATRKEAEAAIMEQTLRSQLAEHQAQITQLRAEIDKKQAQLDRSKLKKSTPKPLPLPQVLTPISNPLPTPPRLVRVTTNKSTWPVDHKTRSNTMPPPRFPILERDDGFDGLEDNAAYFTCRTAPYAWLDDEEFGEESSLQRPIKNAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSZ3</accession>
    <name>A0ABQ8VSZ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Letm1 RBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_757363</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="9">
        <location>
            <begin position="129"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="322" mass="35942" checksum="74A5A027CAD4A3D5" modified="2025-10-08" version="1">MLSRHSIRVQRICLSSTKLSLTPSNLSAPRYNSSNHSKHVPTTSAVGVKELVQRDIRHAERLGVLEPAPADSTGFRKVLHSAIQLGKFYFRGAKLIYTRGKEVNAIKARVRAGGLPMTRQESRLINLQRRDVTKLIPFLVMAIVVEELIPVAAIYAPFMLPSTCILPGQLARIEEKKNLKAIASASEAQDILAKIRKSAVDGTLPISALKGTGSAVVVCGLLRLPTFGNDLLRTWRIRRHLDFLQTDDRMLIQEKEEDSLSDHDVAQALEERGLCFPSPSIIQKLSVKSQRARLKWWLDSVQDTPDNSGTTRRLFLLTEQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT05</accession>
    <name>A0ABQ8VT05_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_929498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF6">
        <property type="entry name" value="GB|AAD46013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="69467" checksum="7FD02E5FA22DFA05" modified="2025-10-08" version="1">MAHDRPDSPPPLSPLTVPVLGEGRPTYSTAPSRSHTPFQNRAHSPTPSEAESEFNPNSNASIRRAILSYENLVTLADAQERLKYVIANRKETLKEARKIVWRDRGEPVVELADVEDCLKWALKGGFRAAGLAFNVRAGFNIVLALIRLPSVPKKHWVSLIQRAIFGLDTWRFAAMLGSFVSIYKFLLNALPFLIPSIRAPSDEYPSAFDDDDDETEKLPTTTPITSTQRRRMERFSLSTQAQRILIRKKTRRWHSALAGAVAGGLGVLWETRGRRVTIAQQLFFLHRGLQGSYNLYSSKYNFHVPHGDVLVFSLVCGQILYGFLLRPDSLPRSYTNWVASAAKVPHACLRMNYDMVRNHTVNFNDVDSIIARSETTPSNKTLLLNLKDIFLKLQTLSPGDPVPYFPHYATCSAIHPAQSSCWSVPTTRFFEVARWMLPIYGALHFVPAVLFKRSTFMQNPWKVLMKAAIGTGRSSAFLGIFVIIYQSINCFKNQSHEYLSTLSPSSPLYPLVQKMPKSVIDLLISKYSFFVPGLFSGLALFVEEKRRRPELAMYVLPKGLESLWIVATGKVGLKRWKGGESLLTAIGMAMVMSTYQNDPQHLSGLVRRILYQFIGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT80</accession>
    <name>A0ABQ8VT80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Octanoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.181</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_893775</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>octanoyl-[ACP] + L-lysyl-[protein] = N(6)-octanoyl-L-lysyl-[protein] + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="6">
        <location>
            <begin position="40"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="29644" checksum="E0F5B00939504189" modified="2025-10-08" version="1">MPSRLPPVFYHFFRTPLPYARTLALQEQLHAIQLSKRRLGAHKDVLLLLEHRPVYTAGRRQNEDSIRDDKLRLTNIGAHFINTQRGGELTYHGPGQIVGYPLLDLSRYSPAMGIRDYICRMQKILELHLSEGHGITPSASEHTGVFLNPTTKIASIGVQVRHRLTTHGFSMNITSEPITWFNQIVACGLADVKAGSIEGVQGRPISLKDEIPALVERFGKLYEREMVEMDTQNEGEIGQAILEMEEDARRSGSWATEPIEAPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTG7</accession>
    <name>A0ABQ8VTG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_33633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="18426" checksum="FC9A2D9D35EC435D" modified="2025-10-08" version="1">MDFVQGLDPSKLALFGAGFSFFLSGFTAPPYNLPIFLFGIYAQENADSAFLSLQTFTGLLGASVFYDIIWMFRNEQGGFVKFLTIILLLVKIPTFLAFGLAARQRGAQFAGLGIRGNDINGPTVWAMPGGFSSTAGYQNVDDEISPQPATRTVAPPSGPTAPVQAAPGAYQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTS9</accession>
    <name>A0ABQ8VTS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_608147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="25062" checksum="3605B8D4CD032761" modified="2025-10-08" version="1">MLTGLEIPIIAAVTGKAIATFKFSRTSVLIDQTRDILNDDHLTKALILLYELNPQLALENDDRRQHAQNMFDNLGRMKGRKYILVRHISARNAKSLAAQYRNEVTTETTDAKIKQAREKARRREQMNHSKDITQKINTRVSGQDHAVTQTPKYIIQTSDMAAFAYPRGTPENPTVSCPVGSKPILPDGFRFGTLAYYYQVSSLDLNMYTNIMDPHSHHTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUC6</accession>
    <name>A0ABQ8VUC6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleic acid-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_812810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302:SF0">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16587" checksum="FE6644C1747FCC94" modified="2025-10-08" version="1">MFTAIRFAASSRAVSRAFSTSASRADVAKLTLVGRLGRDPEVKQTKNDNEYVTYVVATSSFNPGPVDANGERPPPRTSWHRVLSFHEGSNKYLQTLKKGALVYVEAGYELREPEPDADPTTPAGQRQIFLRHETIRVLSHPKSSEQEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUE1</accession>
    <name>A0ABQ8VUE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_812727</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the anamorsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03115">
        <property type="entry name" value="Anamorsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007785">
        <property type="entry name" value="Anamorsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046408">
        <property type="entry name" value="CIAPIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031838">
        <property type="entry name" value="Dre2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273:SF14">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05093">
        <property type="entry name" value="CIAPIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16803">
        <property type="entry name" value="DRE2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S cluster assembly protein Dre2 N-terminal" evidence="11">
        <location>
            <begin position="37"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Anamorsin C-terminal" evidence="10">
        <location>
            <begin position="197"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site B" evidence="9">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 1" evidence="9">
        <location>
            <begin position="270"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 2" evidence="9">
        <location>
            <begin position="281"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="307" mass="32294" checksum="29122825C6B92385" modified="2025-10-08" version="1">MSPTAVEITPAVIPAAVPSKGAALAIGSLSTAQDGKYQALISDLESSRPVERQMLDRLVDGATSLNASTYASAHVILTQSEYFSLLPNISFLLSQLLAGLAPLGTLNLHNLSALDDLSPLTSALTLSGFTLLNTASSTIIAQKPAHSAAGPLRLLNRKKTDPAKKKALWALSSYAPSTPSIDPDALLTDADKARPVPTCEPVNPSTPRRKRACKNCTCGLAELEAEELRHSKVVLLDGKVDGSAVEVNQGKEQERLIQAAKAAPKATSSCGNCFLGDAFRCASCPYLGLPAFKPGEKVEIDFGMDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUL1</accession>
    <name>A0ABQ8VUL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_916877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="51502" checksum="B2A707A930763696" modified="2025-10-08" version="1">MFATKGILVPVQLMERDTSSTSPFDCPVGNLPVEVHSTIFLIGQAIERLEREMEILDDEEFTGPSSPFEVRVSHVNARWRSVALSTGQLWTDFVVQPGYSSESVKAYFSRSKQCLLDIQLRNCPETSITNNILSALFQDSIRWRSCIIEAGLDSWTMNHIVPIAAPNLERVEFVVKAPDRARRFGEVWQGRPVLNGGCPGLKEATLRGFALHFARPPLSSVTRLHLDYRGHLPLSYDEFRALLTNAPSLENFSINGVVIESTPHNHTRTVIVLPKLLRLGISSPHGQVYSGILLTVKAPLLQSLILEGAQDSDLDPFLDAPYDLPHLRSFSLCGSAFAPSKLNKIYVLFPSLEEIVVMDVVFNPSEILRVVSEFIRDLGLAPSHLIQSTLSTSQEPQTLKLMLNPDQRSELRELLQQRLIDEEVVDLDNSKWSFIKFFDWLQNFVTAEILLSVTTQHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVQ4</accession>
    <name>A0ABQ8VVQ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_754111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050057">
        <property type="entry name" value="Prokaryotic/Mito_RF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804:SF7">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="4">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="340" mass="38181" checksum="DBD8F91319C3491A" modified="2025-10-08" version="1">MASPEDIERLRQLKESEPLQDAWDHWTSTLKVLEDIKLLLDDPDPAMKALALEEAAELDQKLSTILNHTFPSLLVPPSTTANLSALVELKSGVGGTESSLFLETLLRMYTRFSQSHSWKANVVVSNENEGGGIKDAIIEIKGSNSYDTLRWESGVHRVQRVPATESGGRVHTSTVAVIVLPLIEEQDAQKEALYSMDDIKLEVMRARGAGGQHVNKTESAVRLTHIPTGITVSMQDERSQHQNKRRAFQVLSARLMDRKITREIAERRARKNSLIKSADRSEKIRTYNYAQERVTDHRIGLSIMNLSSVIEGNALQDFTDALKQDFEETTMEDMLESESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVS8</accession>
    <name>A0ABQ8VVS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924:SF1">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="24799" checksum="88C79A192E0C5B07" modified="2025-10-08" version="1">MYNEFDTRESAPESIFVDPEEVFGKIFGWERFRAAARTEQVTQLFANLEYKLRIFTQRATGIDDVDVYSASSSPKNLTTLNYDKPSPSTTSPKRTHSSQPTNPPSVSVAGYIAYKANISVRINPSCLPYTQTHIEAAGKAEASHLPSVRNSLEEQPAGKGLQALFKGEELAVESALREVCWEKGVFILPPTVAGGIGTGLGNRDIGSGLGGMFGFRNVLWVDIQPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVZ4</accession>
    <name>A0ABQ8VVZ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_863761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="498"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="217"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="522" mass="60623" checksum="4F68BF61509217E7" modified="2025-10-08" version="1">MKGVYKYEEDHALKPQKLLLNKKNKQLELVQERSLEIRRQDEDEAYQAKNNKIEKEIVAIRQKVHKLQLEKEELQSMLQVGEASSSNKLQVCAFYSERDLLEASLKQAWECKNSELKVWSNFTRNCEEFNSLKKEVEALETILGEKDQQLQSNEQHRLEIDSALQSYQSLEQVRATRYRELVKELTAAKQEVHLREAQNEKLQLSFEAMEYSLQARLQEQQKVYQSFDAQLNDMSRRKDLLKISLKEAWECKNQELEKEIQIQENELETSRLNASLQRKEEENDYEDSIEDAVEQLEASCNSLEADLQSEEVKVRDREASLLQEEADHAIICKSLEDRLSAFRRDNQTKVSKMQLKDTQQKLIRANKKNIKSYQDHIAGIEQKVAESQAQGEEMQCQIMQLEYELAQRQTQSKDIHSTVSILQDKNLAKALFIGISQGTSSTMQADQFRVSSPSTGEASIPLMQGIHFGGLNKSLRKAAVVAELRMTTKWEYVLRLSKSKQSRVHMESEEEQDSDEENGKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWZ6</accession>
    <name>A0ABQ8VWZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="58028" checksum="BFF73FD1D4421D65" modified="2025-10-08" version="1">MNFRMEIVMLSRHMYYWKCIQFRKKIKMDISYKTERRTSVLRMSVLPGPQLMESSFDNFVYGNSSLPQSVTSLPAYTRRLSPPSRAHRQLTEHVVELSSDNTNKRAKPWATLRVYSKAPAGSLPTFVEGETITGSVTLNSDMSNSRHVSCVKVIVRGELSSGVLEVDRITFLETSTTLWTKDADATRRNGTYWPFSIHLPGEIIAPSGTMDNVRAYPLPPTFMERKTRACIRYNLIVHISRSKFREDGNLQLTWIYTPTTKPEPPSPLRQLAYQENSPLLGPQADPRGWYTLPSAKVYGTLFKNRIVEVTLKLSLAQPLSYTRGTVIPLSLMLSSIDSQALDLLSSRQALTVRLRRKVSYKRAQNLAEINAPWTSVIPTEPTVDFADAVWWQRPGSLNLNETGPLPVKTRLYRELEGEILLPKSLKPTFHISHFGIEYSVVMLPFDTTGFVPSTPAQKFHNGPILEQRVEIVTMFPKGPRPISHSPPEYQAQIAHPNRTSLPPSRVSFSPSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX64</accession>
    <name>A0ABQ8VX64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_913971</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047323555" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="39130" checksum="B2201C2869BE369C" modified="2025-10-08" version="1">MKGSRSLILSCFLAFALVQSTRAAHEAKVVARIDILGTGTDATTSAAATTSDTSTSSSSSSATSTTATSTTASSTAPPTSTTSSTSATSATPTSATTPTSTGETSQTSAQSTAGNTQTSATAAPTRSIVTSTAANGETVIVTQTLPASSATTASASSSATSGADNSSDDDSSGLSTGSIIGLSVAGGVALLGIISFFVWKFTRKRFSDYDDNEAIRWPELNAHSSDIGDSHPLPVHNTGRSGFDTGSEVSLSRAPSTNTHTNYSTPDLGNDPYAVPPLPHLNPNQPIPYRDDPSAGAAYYDPYRGPVPGTFNEPGSNTEWGPQPGEVYPMTQMGAMGASGRASPGPSMMGRMSPAPGYDMRGPSPAPPMGRASPGPQAAYDNYGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXK7</accession>
    <name>A0ABQ8VXK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_978288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="94" mass="11070" checksum="CE5EF942C11F5516" modified="2025-10-08" version="1">MINPRLWKLHISAGDNQNQLIIYWKKRNDALLIAMLGGDGSGSGQLEEVFLSQRRKRRFASMLSEHFIRILYTYSYSIELMCLFCIYYSLVFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXP7</accession>
    <name>A0ABQ8VXP7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="588" mass="65110" checksum="A4820E0859A18B7C" modified="2025-10-08" version="1">MEMRLPALFSISTNTVDVDLDHSSNSDSSRTMDSYNSVPQSLDAGEDDPMPLAPLNPQTMPQMAPQVPQAHFHTQSPHPPQTPPPQTPPLQTPPPQTPPPQTPYPRSEDFHMDDINATPRAPPDMTPRAPQGPRNQPIMQQPLSPTIQKGKRRRVHDPEPGPSKSNDKTPGAQPTFHTGAQSNTQSNSQGPIDYLQALLNHQTKTMGELYHHLQNYTAEILQKQDQVLQKQDHKIDKVVSHLAQNTEILGRIGETLDMLSGKSKHKGSPGHQDEGDSQRHGSGSNQGPQPSNDGDAAAKPSDGGAAGSTTNHNNSNGNGEDGDDEGDLNHNPFFCYARKKQPARSEGVKHRPTEELKIKETMRKWLNEVMEGQDQLKEAVSQDKADEFTLLFKTNPLACPCSVDDFRYWIAGGPKSAWNKGASYVFVEILEKRKLIATPNVQTCDENAGGQQKSSLSIFQKVAAENTLFHHRREVIITFHSLESFLSFFDELGVTGMSSDDEDPGMKKPQVQYIIKEPKCSKTKYVSGLPANFYDAQWLEEQEPGWAKGGSGFVNEFVRPRKPIKLIFPADLLKTLKDRGYPRAQGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYC7</accession>
    <name>A0ABQ8VYC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_425867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="700"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1036" mass="116594" checksum="D4E2BCFD8C7F17B7" modified="2025-10-08" version="1">MNCHLRVPRAPTDLLRLESIKILARLELIIEFRPWITAKSHRREPAYRVLFDCFSLGAPLGVLLDLLGSPAPSYLNVDVDSFNFGLSLAERERFVESFIQRVNILEIQGRLSYGEVLRVDDLFNGTSSGFMKVLKTVNRILAALQDCYPGIFVTAKDTESRKSTAMEELVESEHIHVGFLRMVIDHAAFLSCESKVLETALESVVVIEKRLRQYHDRVLSSFQQAELDSSFLGSPDWEILFSFDQQSVQNNMASTYRSLCTSYVSLYEYFEQIIGTLEPVLAAHAQMLLDILSYLPTRISDYCEQLQYILSLTLPDTLSTEIHRSQHDTLCSTILKMTHISTGINEMSWELRTLRAVKILKGRAFHWHSPGTSRRGLIIDPSELGTLILDDELVAEDAKTTSGSALYQIFLFDTMLLCCLPGLQSNSRHHGFNDEHIGSARYPIRPWELGPALRRTVPLNLIYAIPTKEMVELRLLDSDCFELDWSPNSNQDQASRFAQSTLRLSFQCTSGQGQYNQWTSVLEEFVHTVIDARYTSFNPGGEPPHPKTKIEGYNGDDGDVQSLALSEDFPDDLSTEFAKFNLSESSDGRRHSHPRPWSLIARKGPHSESSSLHQQLLEEQGQELEDILSPNMLPTLFTSISIGSKGSITPLSPIALGGVMRDPTEFQHMVMPPTPPPEGDLVYEIAVSERVMDFTGQISLVGGCAVAGGGYSDVWRAILNSRKDGHGQELKVAVKVIRPNYGNPENEMILKRRLARELDVWKQLNHPNILPLYGTTSGFGPYDSLVCPWMENGSVSRYMEKWGDILSMTDRLQLLCEVAEGLCYLHSHGIVHGDLTGSNILIDDNKHACLCDFGLSSIVSEYQGAFSTHSTISGAIRWADATLFIAQAAQSEMEEPLDERQEIMPMLTAKSDIYSFGSVTLEILSGRIPYHYIRGDAQVIFELAQGRKPRRPNASFITDSQWKFISTRCWHDVPDLRPDAEEVVNTMRRLLRVSLEFRRHTGAGDVWDTESGEMSLWGEPSDILNLARRHSEPLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZT3</accession>
    <name>A0ABQ8VZT3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_19915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="125"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="50"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="21341" checksum="F4ADF3E261023B4D" modified="2025-10-08" version="1">MVLCGDSRILNRLPRPLHSPRRYQQVPQLGNLSLTQLMAQQQSLGLPPSFLTTAASSAPTSASAPTAQLSSTRRSAPEEISPPPPAKRARSRKSSMSVSSPDTPVDYTASPESTSATTTPLSASEDKRRRNTAASARFRQKKKEREAALETKAKELQDQVTGLEKECETLRRENNWLKGLVVGVTGAGAAQNSQTATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZX3</accession>
    <name>A0ABQ8VZX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_750259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF49">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="46784" checksum="D8ECF7C48B100329" modified="2025-10-08" version="1">MLIYLLCSLDRSNIGNAKVLNDTTGNDLLQSISLSTQDYTTALMVFLIAYFIFETPSNYMLKAFRPSRWIALLMFSWGAMTMCLGAATNFGSLTAVRFLLGMFEAGLFPGLVYFLTFWYKPNERAIRVALILACATLAGAFGGAIAYGVGKMNGTGGLEGWRWLFILEGIPSCLLSLLVLALFPDYPETVRWLNAEERELATRRLQGLASVGHSKISWEEAKKTLKEWRLYVHYIIYICISVPFSSISLFTPTIVSGLGYTGLDAQLFTVPPYAVAFVVTVTISWLSDKYEKRSIATSFCLFIAGIAFIVEGVLAPTAFKARYGVLCVAVSFAFASIPPLLSWLTANLQTTGAATLGVPMNVSMGAIGQIIGVYIYKASEAPGYPTGHFTNAAFALLGSFLALVLRTVYVRWNRKLGINEREWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W008</accession>
    <name>A0ABQ8W008_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome b subunit of succinate dehydrogenase, Sdh3p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_192258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018495">
        <property type="entry name" value="Succ_DH_cyt_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02970">
        <property type="entry name" value="succ_dehyd_cytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000178">
        <property type="entry name" value="SDH_cyt_b560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01001">
        <property type="entry name" value="SDH_CYT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="16056" checksum="7657269A9DC8742A" modified="2025-10-08" version="1">MLYSIQTQSLKPEDGTTILNKQRLQRPSSPHFTIYEPQLTWVGSIFNRITGVGLGFLLYGFSLAYLVAPGTFDSAHVIEFVNGLPDAVKYTGKFILALPFSFHSWNGIRHLLWDSGKFLTVTGAYSTGYAVLGATAISMLVLMFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W085</accession>
    <name>A0ABQ8W085_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_805660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="109" mass="12316" checksum="44D90C3C19EDA6B8" modified="2025-10-08" version="1">MRSSVVPRWISSTCMQYSICFLHCAFHHWLSLAVAVPPSIYLVHLPAMTPLHLSMISSTPRLHTLKISRLMNLPVLLDSPLHYSKTLQLAEQSSCTFRSPYSDIDSSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0T3</accession>
    <name>A0ABQ8W0T3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_2382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="134" mass="13896" checksum="BDAE40A523699476" modified="2025-10-08" version="1">MSVNDRSVGGAVGVDTYPGVANPTSSSATSNPMVNNFVTDPTSEERGAGAGANFEGDRQAARNFSQTSGVVEGRPGVIESSNIHPLNENSNKDDGWANATKQPGRTTENFTSTAASKVTDVANKAYEMAVGQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0V5</accession>
    <name>A0ABQ8W0V5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_430651</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040684">
        <property type="entry name" value="HMUDK_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18723">
        <property type="entry name" value="HMUDK_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="324"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="384" mass="44650" checksum="BB24F2C14BC8D34C" modified="2025-10-08" version="1">MTAVELESLFPRDVCSWTQDEIMQTKFFCNTYRVLDKTSQYIITQVIQKGSQEPVEIVFRVVLFNIFTKIETWQWLEKRLGPITWKDYNRESYMNVLEERAQTHTLYTGAFQSPGPKWDYPETYKNHLLLLETLMDNDLAGKLQMFKSMEKAYAFIASFPSMGDFKSYQLLLNLSYSSVINFSGNDFVVPGIGAVSGLGKMFGKSIENAAKVDPNIRIAVIRYMMETQQQHFRRLGLHLSGLGPNHLPMELADIEHAICEVDKYARKAHPWIVDNKNGRSELRRKWTPSSEPYPATPVLPEAWSHARRNITRRCNIMPSVQKRWAVEKIVTHRVVKGRIECNVHWYGYSAKDDTWEPVETLFEDIPDVVDDYWKKYFGKSYSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1R9</accession>
    <name>A0ABQ8W1R9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD/NAD-P-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_807937</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045123562" evidence="5">
        <location>
            <begin position="20"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="596" mass="67669" checksum="44DEFC9222091659" modified="2025-10-08" version="1">MHKLSWLTVLFLATVHVASVTVEEPQTVLDIPIAGQTITVEEPQTVSDIPIAGQTINDEPSGKWYKFNSTIERVAVIGAGPAGLQAAATFVKHNFTVRLFDRAPGPGGNWLYSDEIPVRESYPDAPAVEEHWIPEELPASEYYNEGDDDLTLDSRWREHWQPRSIWDSLHTNSPAVITELPDVPYPPDHSWVISAHTIGAHVRAYASIHNLNANDNSSVHSYSTRVEKLSKRPDGNGWTLTLKHLKKLEEPDRLKATWWTEDFDAVFVAPGPYTSPHVPEIDGLLQWSNVRAVDDPSLFSVYHSRVYRRPERYTGKTVLVIGVGTSGSEIARDIAPVAKKIYASHKEYADWDTLHPFQRRSFRRFPDETEFVPKISHFESLSSLDNGIKDGKIVLVNGTVLENIDEVILATGYKRSNPFHLSVLNQTFGAESLEAPPPSDVFTGPALKYVHWTGHFIPDPTLAFSTIRPWTAGQYQYYGQAKVWEGTAHLPNEAGLWAQYNSTRYTFFRGLFGTAPSEAIVRQYVTWLNNESLENGGRLVSPWPVQNREVFAYYANQEWEKDYLSKENFTKFENIPDRQWTQKDIWDISVFEDDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A8G6</accession>
    <name>A0A9W9A8G6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8J55DRAFT_606821</name>
        <name evidence="10" type="ORF">C8R41DRAFT_898375</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000020">
        <property type="protein sequence ID" value="KAJ4476359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A8G6"/>
    <dbReference type="OrthoDB" id="14535at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20266">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045299">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016488">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="9">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4466203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4476359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="135" mass="15801" checksum="2D78084850D9CDDA" modified="2023-11-08" version="1">MNTFTIPARLARPAVISETHAETRKRAIQLYREWYRAAPEMIAVYSLNYSPQYIRHLLRQRFEANRHVTDLRAINVLLLKSRQEYQETMNAWKLPDQVMGILLKPIEGPQQKTFLEKFYNGRDEEAIKPAASGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9ABX5</accession>
    <name>A0A9W9ABX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_430051</name>
        <name evidence="7" type="ORF">C8R41DRAFT_893795</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000017">
        <property type="protein sequence ID" value="KAJ4478656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9ABX5"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4478656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="194" mass="21765" checksum="1C32DE7A89D4B290" modified="2023-11-08" version="1">METSFAITGKGYVIVASDTTAARSIVKMKTDDDKIKVVSPHLLMSYSGEPGDTIQFAEYVERNLRLFNIRNNYSLRPSAAASWIRRSLAQSLRSRKPYSVNLMLGGFDVTTDSPHLYWIDYLGTMTEVPFGAHGYGSYFALSLLDRYHDPEATLEEGLATLKRCIDEVAKRLVVSPGKYKIKVVDKDGTREVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AH74</accession>
    <name>A0A9W9AH74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mov34-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_427746</name>
        <name evidence="11" type="ORF">C8R41DRAFT_758907</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AH74"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="9">
        <location>
            <begin position="24"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4481720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="301" mass="33572" checksum="2004DF24D4F42C7C" modified="2023-11-08" version="1">MMSGGRGGMQARGDGTVPDNGEVIHISSLALLKMLKHGRAGVPMEVMGLMLGEFVDEYTIQVIDVFAMPQSGTTVSVESVDHVFQTKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSSVDINTQQSFESLNSRSVAVVVDPIQSVKGKVVIDAFRLINPQTVIAGREPRQTTSNIGHINKPSIQALIHGLNRHYYSIAVNYRKTPLEQAMLMNLHKRNWTEGLKLRDFNLHKEDNEKAIKSMLTLSEAYNKSVQEESTLTPEQLKTRHVGKQDPKRHLEDAVEKAMGDQVVQNLATMLLAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DFK7</accession>
    <name>A0A9W9DFK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S12/S23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_525201</name>
        <name evidence="7" type="ORF">C8R41DRAFT_917747</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000039">
        <property type="protein sequence ID" value="KAJ4467924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DFK7"/>
    <dbReference type="OrthoDB" id="1713912at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4467924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="145" mass="16014" checksum="9F6697E4D1D1A7F8" modified="2023-11-08" version="1">MGSNKPRGLQAARKLRNDRRENRWADKTYKKRALGNIYKTSPTGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLISGFGRRGKAKGDIPGVRFKVVKVSGVGLLALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWQ2</accession>
    <name>A0ABQ8UWQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_133675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27001">
        <property type="entry name" value="OS01G0253100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27001:SF931">
        <property type="entry name" value="OS11G0664100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="29"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4464075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="36142" checksum="BB201F04281A5BCE" modified="2025-10-08" version="1">MISDEIFRKNWRLTREVDFDLKSKTNLYHAIIDLDGQPSYDEIWYKKDGGELYVRIHDIPGTLSGDILRLLAPLPSLTTHSEIKGNLIQSVPNTPLADVEGFEFPDQDTSTVVIGLPIITFNEAIHFAKTSRCLSEVPNLLRAKGGPHIVELLGRTEDGLLVFPRYLDSRASSVLKGDELSIAWLRRVLLQLADALVFLHGQGIIHRDVAYRNVLISKDLQDVYLCDLEGAIGSDICPEIIAAGQVPPTQRPYTDKSDVYMFGITLTDFILGNSTMNRWCYTSHWVPPAPFDVIAQACLKTAPHERPSMMEIRAMLEAIPVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX82</accession>
    <name>A0ABQ8UX82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_717426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000138">
        <property type="protein sequence ID" value="KAJ4464590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="88" mass="8314" checksum="A12004B4D96ED65D" modified="2025-10-08" version="1" fragment="single">LTSFLQSVLSDITAGAGSVLGDATSLFGDATSIAPGAGSIFTIVTSEGGDAITLAESAGGQVTSFAGHEFTVASNAVVGSATTSSTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXB6</accession>
    <name>A0ABQ8UXB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_906749</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4464179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="330" mass="36400" checksum="A2EF823708384C07" modified="2025-10-08" version="1">MSKRLASLFAPPSKEEINACWDLCRLNNHMGCWTTWIPTAWALAMVYHAQPEIPGSVALLWAAKYLVLCSGIKSLIMVSLGIIRINDFGIESKITVQSSPDIDAMVSRTKGRAIPRGSISLERAWMFFGIQVVLGVFLAQALLDPVSCRFAAAAAPLFIIYPTCKRWMYFAPVVLGLMFTVGVFMGWSTLSRTKEMPYGMLVPIYIGGCFWVWTYETIYQHMDKNDDVKIGIRSSALLCGQYTIPVCFSTAIAFFGLLTYGGYLNGHSYPFFAGVLLAAGLLLSKLLRTDIDRPADCRDFFLQTPLIGQILVGGFVADAVIGRISNGIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXR9</accession>
    <name>A0ABQ8UXR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_912537</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4465126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="313" mass="34032" checksum="310AB603052B28EA" modified="2025-10-08" version="1">MDSSELYHVKQQFVLGAYKTLVDLTLPDPNSPDFLPILIYQARSHIALNNPKAALQLVPADSENVALKAVATLAKFVAAEGTADKEALLEELRDLSVEIEGDDVEGSDRDKATVRVLAGTAFARAGELEEALETLGADSEDPEAVAVIVQIYLSINRPDLAKKEYERSKRWAEDDLLLQLIESLIGLATGKDGYHNPYTFYTEQLGNPSLSSPHVLTARGVTRILRNEFPEAQSDLQESLEQYKDDAEALAASAVASGLSSTKKGETDANELWARLTSEYPNHPSVVDLSQKSALFDEAMAKYTVPPLATATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYK1</accession>
    <name>A0ABQ8UYK1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydroxyneurosporene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_871711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057722">
        <property type="entry name" value="AsqO/PenF-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056402">
        <property type="entry name" value="DA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25581">
        <property type="entry name" value="AsqO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24137">
        <property type="entry name" value="DA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045397507" description="Hydroxyneurosporene synthase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Diels-Alderase N-terminal" evidence="2">
        <location>
            <begin position="32"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="AsqO/PenF-like C-terminal" evidence="3">
        <location>
            <begin position="252"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4466016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="40544" checksum="F5E2B8582A11A3DF" modified="2025-10-08" version="1">MRLPVKSSALLAAIGFLLVEAASASLSVDSQASVVVIPPTVSNGLTEAQFISSTHGLDGPKLSNINSTAFGEVWYFNTVSEDGKYSVVAFFWASPSPSLTAQLQNEKILSAQVIVREDDDIYSANSVFAETAEIFTSAKGTSGLWLGTGCSFSGSQSLSTYSVNFSSPFEITGSIILESVAPAHYKCSSAEAGVDTQILPNFGWVNAIPDAQTTVDLKINAKNIKFKGIGYHDLAWSNAPFFSKAKGSLFTEYQWAHGRIGPYSVVWLVITGSDGTNLTSGYVSRDGKVLGTPCSNVSVTPQFNTSTRQIRRFFAQIDLRHEGTLYAQLDVGGILINDAGFVAGSGGLSGGLSSEAFEHTGVASFEYYRSVQLPEMPSGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYM4</accession>
    <name>A0ABQ8UYM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FMN-linked oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_782999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000144">
        <property type="protein sequence ID" value="KAJ4464255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15677" checksum="7FB021F010F724F8" modified="2025-10-08" version="1">MPLEETIATFTHFITEADKLGIVYVDLMRYSEMLDPVIDGEKRATKHDILATYSPLFKHTKIFSNAGWTGEEAAAAIKDGKVEGVFFGMGWINHPDFAARLEHGKPLDNPIDFTTLYGTYHGNEEEQRKGYVDYPAAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZF9</accession>
    <name>A0ABQ8UZF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_856722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF189">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="49"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4466577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="571" mass="60843" checksum="5FB950875DDC8DC0" modified="2025-10-08" version="1">MTSVVTDNSIQASSNLDAVQSNKIKPETKTTLELTDQTNLLPVRQVVIVFLALSLCALVTSLDSLIVSTSLPTVSAVFNAGSVSSWVPSAYLLTSTAFQPLYGRLSDIFGRKSTLCLAMTVYFVGNLAAGFSNSIIQLIVCRGIAGAGGGGISSMLQIMISDIVPLRERGKYVGISAGVIALGYAFGPIIGGVLAEKASWRWCFWVTLPLSVVATIMAVIYAPFKPMSGGIVQKLKIIDYPGIVLTLGGCTLIMLPLIWGGITYPWNSVIVLAPLCCGVFVVVLFCLWEWKVAKLPIVPMHIFKHVTVVGVYICMFANGFVFFSALYYLPLFFQVVLGYSPTYSGTFLLPVVMSQVVSSLTAGLAVSHTGKYRTVVYTGFALSAIGCGCISIFNASTSKAVMVVLMLLTGFGNGMTMQTTTVAAQASVARKDMSIVTAVRNFVRMLGGAIALPVASSLLNNAIRDFMKNLGFPSSTISPVIDKPSLLNSPSAISSLSISPSQAADILSKGYIKGFRDVFLLNAAMSATATLVSVVMIKHKELLRGDEEQLRKEAAEALQTAKTKVVEKESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZK1</accession>
    <name>A0ABQ8UZK1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="473" mass="52200" checksum="E02BB191D7A0FB2B" modified="2025-10-08" version="1">MSFNFGSTADFEPRPSDASPISTPRIGSYPNFLRNIDNPAGVGMGATSRPQRDLAVAANRPYTPPVRPPLRLTHGISSFAAPSNEQDVRHLGLSPDGYDDCPPSPMNRSSHFSGSGPAYSTSNEDVDELNEFDGRQELTVPIFNSSMRKIPRSDSETAVLMTWVDEIGAQFALEPNQVREIKGMVMLACNMETEPLKLHLLTHAAICRSENKYASNNLQSSSVKEVVDVTMNQLSKHVEIPADTKNVLHMIARDECANPTRSSYADVGIAVWARCKAEANMHDLTEMLSKTKSETALKKAAKAAGNKILQQFRDDIMMTIVVDESGKKETQNLEKATHALCKKYVKGGSGGTLHQFRFAMIRRFMRKSECKEQGPVLKRRKTNNGGQKIDDYGQNMKVGKWKEYFCETLQADWEHFGKPSNTLLPALPIAANSNGTTTGRAPLAEVPNNAHSVPRVLGVEDGLANHDDEYTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZS8</accession>
    <name>A0ABQ8UZS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_931209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27789" checksum="A6E5A57B030378FF" modified="2025-10-08" version="1">MLILRIWYLFPHNKFIQYGMIILWVFSVAISLAYTSVAAMGLRLPNTSLFMQGAPGCRVARPVKFWRMFMPSLGLHTILYIMTAVRALRNRRILKDAPVLKRLLRDGGLFFFVVFVSIGFTAIGSFLENVPQINIPVIFSNYLLAVTSIAMSRIMFSIHSLASHLGSETGWLLSNVELRRTNWRKGATEGELIVECNSYDDHDDRESNLQINNGSLRSHSALKVSRVGMFNDDTMWLQSNPHNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V041</accession>
    <name>A0ABQ8V041_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP synthase complex subunit H-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_855404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019711">
        <property type="entry name" value="ATP_synth_F0_suH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10775">
        <property type="entry name" value="ATP_sub_h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="127" mass="13447" checksum="EAABEA6E9B63D5AF" modified="2025-10-08" version="1">MSNILRRAANAAQNGSRSRFFSSSVAARKDLVQDLYLKEIKGYKAPPVAKDAHVGVVKSYSVPPAPKAPSLPSDIASELAAYDTSEPVSASQPAAPQTSGSEETVSGADAYLSFLEQDLPKPEAHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V074</accession>
    <name>A0ABQ8V074_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_925635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="90"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="185"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4467788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="447" mass="49769" checksum="8218080E298C6369" modified="2025-10-08" version="1">MRHFDNTHITALTDLINKATQDVIAEYAAVGQAVPSLDTLQPGPFQVPEETPTRLIRAIQIIEAACAQLSFTVAPPGSVMVNKSLEHEEPACLLVVTEARIADLLLGRPEGLPASELASRSGLDAKRLTRILRLLATKHCFKEIKPGVFANNRLSMKLLSSDTVSSIVCLLTDESLLASAYLNDTLTDPSEMDGGIPFRRATGYPFFDFHKTRQGLKKGERFPRAMVGWGDVTGKGFLAKVYPWTSLPADTTVCDIGGGNGHVTMSLMKAHPHIKLVLQDQPQVIEMARKFWDKEYPKAIENQRVEFVPFDFFKDAAVQGCDFYYIRSILRDWPDVESEIILKNVRKAMKPSSRVIIHDTVLRDAVHTHETSSNEGTVQLDIAPEPLLPNYGVARVRTYELDMTMMNLLNAQARTLPEFIELGKNCGLKFENLYEAGEVDLVEFSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0F1</accession>
    <name>A0ABQ8V0F1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Septin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_44244</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="14"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4468027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="535" mass="60751" checksum="E02FAF3E7B86B1F5" modified="2025-10-08" version="1">MPPNITKRRRSKAKGVGFTVMVVGASGTGRTTFVNTLCESEVLPHKDCDNPETAALETGLAIKPVNVGTFIPLVCVQSAVLCSSLSLAAQLLEIFRRNLLITTPLFASSDIEEDGLRINLTIVDTPGFGDNVNNDLAYVNLSYSSTLALLAGFILIHAAITFHGKGTWNRQIAFTSNVVIEEIASCAFFILLLLSRMILTRDVFMNFSFQEIVNYLERQYDDILAEQSRIKRNPRFRDNRVHCLLYFIPPTGHYLREIDVELMQKLSHRVNVIPVIGRSDSLTLSELKAFKKRVMEDISHFDIPVYNFPYDVEEDDEDTIQENQELRSLLPFAIMGSEEEVEIDGEYVRARVYPWGVAIVDDPEHSDFSRLRGAILGTHLQDLKSLTEDVLYETYRTEKLSRTTGSYMEARESTMLPAEDLANQSVRLKEEQLRKEEEKVHPEIRSISQLTPFFLLSFTIPPFLSSMFMFSVLSSPPFQLREIELRVQREIHEKRQQLLAKEESLRNLESRLAAQGSDSILGTPILDTPVNFVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0F7</accession>
    <name>A0ABQ8V0F7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HORMA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_71277</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051294">
        <property type="entry name" value="HORMA_MeioticProgression"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225">
        <property type="entry name" value="HORMA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225:SF7">
        <property type="entry name" value="MEIOSIS-SPECIFIC PROTEIN HOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="7">
        <location>
            <begin position="16"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="790"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="333"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="796"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="817"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4466587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="865" mass="96851" checksum="88AC4074EAFBD5D4" modified="2025-10-08" version="1">MQAQANRTEAKTVSSAQSLAAIQTLLRAGLGCITFMRDLLPQDNFTESHFTSTDDSCMSQSSSNSTFSSPANEKKNVNGFKIMTMSRGYTDEADRILNYLEYGIFDALQKQYLRSFIFALYLDNNDPNNIVEAYTFNFQYHTIIGTEIVVPVMSLSDDMRRMSLKGKDPVAEAAKRGAIPTLRDVKRSVKTLLKTLITSMTQMDVLPKRRYATFKVFYTDDTPSDYEPPHFKAGDYEKDKWYFATHDVEEVPDNWSVGKVNAGWHEVDVSVSSIATYLPSSTEHDNQPFGGTVARSVALVPPGLTPAGEIALRAEEIKKQIVDANSRRVVWAAEDEPKEETEETETSGVSGKGPDIVRKPIPLGIKNDNGEVRCLDADETFEERHYYGPSPIAPLGLKDIQRPINSTPTSDFPQTQLVNDSDVEDSNIGEDSHTNSGPRLMRRQESTVSEAFSMSTSFAGDSVLDTPTPHPTTRRCIDEVISRSSSPDSFMTPDDTRLGSRTVSIEMGVSDNESRGIEANALMEKSASSYDGGMDDIEDEEMLDLETQVVEAINPQLIEIQLPDPIQSFDSSKALPTSNRAPPPASNFIPVAHKMQVQKPKDDVVDCECGIQEEDECCSCEGGCDKWYHIWCMGYHSVQDPRLPEQFICFNCRLRADPSWELIKVELYSSLIIKFRELASFRRALKVAEKHSPLTAVEFAQAMGCENTQARQLIKRLETEGFIAEETTTTDEIGFVQTRAKTMKGKGKNAKQSKLRRGLQKQRFVFNLKSVRCQEYKDYFDPSPEVESRLLGIPQTRASLKARNTTARNPSRPEPFPQTQSAQSQTQDDPEETFTLKRPPEVNTDSPRRKKKVKISITRGVDLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0S3</accession>
    <name>A0ABQ8V0S3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="283" mass="31081" checksum="3E7216C35D79CA60" modified="2025-10-08" version="1">MSVSTPGAGFSDTVSVINNEKDYFDFVQTLSPTDNSNNLNSESLPTSFPESEIQNKSTVPKPIDLATAIANFRPTPKEIINGIAPHVFDERRTKSRRRRSLNRRGSLGRGRPSSVSYDFYHPGLAGMHGSAGHPTHSGLSRRSSRTFDGAIPRPATAPYYSSSSMKPGLSPLRISAVITVEKIDTLLGAESERRQIDDHKVKNSEFPQDSLTLPTLGSNAERKSRMPRLELTLGKRKTASDEGTSSSSSLPEDSNKRTSTRKAKWPLIRIDIQVLRSIGSKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V170</accession>
    <name>A0ABQ8V170_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_860827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000152">
        <property type="protein sequence ID" value="KAJ4463804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="31103" checksum="111C6824151E0B7E" modified="2025-10-08" version="1" fragment="single">MPPRASERHSDYNNPNQRWHGKREFKQERGDDEHRQFKRPKRGPRKDRHMGDRFDEDGYDTTSGEEDIITSESNERPIAKKEENGFRIKSEPRESAANTTKRGDSPSSCSVSKQEPSCESKSSQQTSQQSQPPILQIHVIDLKTLFYSSTGSHTGADSVQGMARELNSGGGGIPLYGMLGKGEYGSGWDAELMLSIFQFFVDGRTINEQRATASSRMEVEKEEKIERQKRAEAERMQSQSTQAGLDDDIDPNEVRPSAEGQNPDSELGEAWEDWGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1B2</accession>
    <name>A0ABQ8V1B2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_853334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="195" mass="22734" checksum="E445761E29A811F6" modified="2025-10-08" version="1">MLFLPFSFGRTCLYSLRTHSSDSETLRQRLSATEVQIKGLKKESDKLRASNESKKRRFEQAKNDWKEKNAQLLAKYTCKKRKLDDAMSALQEMKERLDVSHAANVQETAALAQLAKSENVWQKQLWMLQAEVDEQSDKSTFEARRAEAREEAAASEYHSDLTLIKERERLARDDALRWKARYKALVAKWVYHLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Q8</accession>
    <name>A0ABQ8V1Q8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-3' exoribonuclease 1</fullName>
            <ecNumber evidence="5">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_852455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016494">
        <property type="entry name" value="5_3_exoribonuclease_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040992">
        <property type="entry name" value="XRN1_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18332">
        <property type="entry name" value="XRN1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006743">
        <property type="entry name" value="Exonuclease_Xnr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 D1" evidence="10">
        <location>
            <begin position="730"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="11">
        <location>
            <begin position="928"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="9">
        <location>
            <begin position="1174"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1246"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1388"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1334"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1345"/>
            <end position="1360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4469792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1421" mass="159483" checksum="B0F9A7540C82A618" modified="2025-10-08" version="1">MGIPKFFRWISERYPLTSQLIQENKIPEFDNLYLDFNAIIHNCSHPNDDDAHFRLSEEQIFTSIFAYVDHLFGKIKPKKLFFMAVDGVAPRAKMNQQRSRRFRAAKEARELRQKAEAKGEKLPEEKAFDSNCITPGTPFMARLSEQLKYFVNKKISEDSNWRDVQVVLSGHEVPGEGEHKIMEYIRLSRSQPDYDPNLRHCLYGLDADLIMLGLLSHDPHFCLLREEVKFGPARKSRGNSSLDSINFYLLHLSLFREYLHLEFNSLATELPFDYSLERIIDDFVLLAVFVGNDFLPNLPDLHIHENGLEKLFEVYQKVLPTMEGYINDAGTINLPRLQFILDEMAQWEVDVFEKENSDTNWYKGKQAKYKNGATPKTNELVITKPQHDIFRAVRDWLMTKPTKALTMPNDFPAKDRLFILTIARDLNLSLAWDEYDEEGRNILSFTPAYAEDAFDDEEQEAQVAVLRVLRKYEKAPIDGGEEDFDTRATNALSHKMDEWKRGYYSGKLEFSYDDPEQMQKLVYRYVEGLQWVMYYYFTGVKSWAWFYDYHYAPRISDLSSKARWGGEGGIGRRGIAQLSFDFKLGQPFRPYEQLMGVLPAASKDHIPTAYHDLMTSSMSPISDFYPADFEQDLNGKRADWEAIVKIPFIDEKRLLAAMSTKEHLLTDTEKQRNTFGTTTKFTFRGLNVEPTEYPSSLPGFFPPLHRCMCKMEVFNLPTLDSDLNFPLVTGLVEGALTGPSALSGFPSLNTLPHTHTALGYHHVNVHGSESRNQSVIVYVKNTYEERKTEDIGREVLGNRTFIGWPFLSEGLVVGVSDELFRYETVKVGTPGRGTEKVLGTPHSQSGLGLWKVKADKIEGVYSKRFGVVTGPVEVLLHVRPLKGLKRLEDGSLVKEYEGIDKETEVAVQMTVSAVGVEDSRYLERPAPPLSEEFAEGSKIFFLGEHAYGVAAQVSATTDTSLSVILAFFPSDKAENAEFKAIAQEQTSSSASYYPAFRAAEMLGLSSRGIARITSSFLIISSDNQKHNIGLNIKFEAKSLKVIDYSRKEGRHWEFSEKAIKLIKEYQEAFPDVFKCLDINVDGMLRAVDVLPGANPDARVKDIRSWLKSKGVQDFEAVTLFCDQLGKETITQIEKLADNFNGNRSTTGIKKAIVKGIPRQAVLKPAHAIYRLQGQRFALSDRVIMVQDSGGVPLGAKGVVVGLNTKTMDVVWDMPFMSGTTLGDRCSQYRGLAVEFNSCLNLSDPQFVTSTNPKDQKQPLPVNHAAPFKPRSGPYPLVRPGPGQHPAAGFRPAPQQPSSSPPKPVHIMTNPQHQHPRGAVARGGITRSGFVPPTDHTRGPSHDHLANAPNANAHPSAPVANEGGYTPRGRGFHRGGGGFNSGLGYRGRGGFGPSMNERGRGGRGGGFRGRGRGYVPAPPLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1X5</accession>
    <name>A0ABQ8V1X5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_723532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27430" checksum="66D9CE415578C8EB" modified="2025-10-08" version="1" fragment="single">DYLETWPRDFSSIWKRRKTGISVLFLVNRYMLLLSVTIQAIFIFPGNGTDVLCNQWCALNLTTMISTHLIEVLFALRVYAIYSRNKVMFCIASAFVISRTALDILVSVIITEPVGIGCLCFICEITMAMQQYSDLQLAIPFLALGYDIFIFVLTAMKTVQHSLEMQRLNQSSITQVIIRDGTLYFLLPNILISRLMLNLRTYSEPGNSTISQGQQTHVSSLNFASNQMLGNIGAPLDGGSFNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2V0</accession>
    <name>A0ABQ8V2V0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_801588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="65"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="413" mass="48086" checksum="8B95F75614654560" modified="2025-10-08" version="1" fragment="single">MVCQLKKLPRTTKNAGFIPTLYIDGIDHLQDPELFSHTFALDTQDLIDAIYSFVGTDGCSRRVVIQSILHHAEDVVGLCAVVAEVQCLCMEADCTWNGERKIVKISFMNTDRQSEQGLIEEARSKAESTGELWALNHLPNAIHSLSLLPNKKKAFHSRLKTYLKDKYEERVMHVTVFEKLHPLSELEDSRDFAQVFYDTLQIHQWLYECARILHCDISSGNIMFRRKDGKIYGVLNDFDLSARVEEMNKSDIRTGTKPFMSLDMLDSYWKGGHLYRHDLESLFYVMLCLASRYEQPGVAAVEPRAYSLWFSGTDREIFHNKFTFLIHPFVQSPPIQSYFAGFKRWLRKIHRELCRGYRQRPSCFKNLSTSEEESEDEDLQFLEKDNDPNFDWNTLNRHVSYVRMRSIMSSFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3I7</accession>
    <name>A0ABQ8V3I7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_852427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF94">
        <property type="entry name" value="PHO85 CYCLIN-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="572" mass="61660" checksum="7EBAA9CD7384B2D3" modified="2025-10-08" version="1">MLALVHPFNPSPDTPHRNTTSSRSRTPHHRKPTPHSARETSSSPFPTTSLHSSSMFSAPKSVTTSRLSSSTQPFVHRQPSTSNSESASVTTPEHLQPPPTVAPGEIETPVAQTSFDIHSYPPHDLLRLLASLLTQIASTNDKLDAASSSSTLLSSSSTSSELHNVVWRSLTTASRSALSTPSSTLTFHARNIPTISLESYLLRILKYCPTTNEVFLSLLVYFDRMTKLTSEATGRSFVIDSYNIHRLVIAGVTVASKFFSDVFYTNSRYAKVGGLPLAELNQLELQFLLLNNFNLVIPKDEMQRYAEQLILFSSNKSPSPGVSFSSSITPRPTATSTTAPLQSNDMVPMRCMGAIDAYGGPIPGGESPASSSLPPPTNIPFSQSGTSMSRQGARPGVESNALSRIINPSQHQPHHALNGLVNGNGFSSSLRMQHQEDSESEGAETETETETEAETETDGGWTTDDEPTIRPPKSSAGSSSSSSRSSSASDALSICSSVSENDSVEGDDEREDHVMSDIDDDEEGGRTPEHSAQAETSKDGEKTPERKPFQGLLGMSKITPPGRREHEAMDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3I8</accession>
    <name>A0ABQ8V3I8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_984794</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="702"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="707"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4467580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="734" mass="80552" checksum="56662E4B79B193C0" modified="2025-10-08" version="1">MSIKAPRKGENYELSVDLNSEYREKRKDAIKRVIASMTVGKDVSGLFPDVLKNMQTDDLEQKKLVYLYLMNYAKTQPELVILAVNTFVKDSDDPNPLVRALAIRTMGVLRAEKIIDYLCDPLQKCLRDENPYVRKTAALCVAKLYDLKPELVIDNGFLEQLHEMIADSNPMVVANTVAALTDIHIAASSQSSISSNDPALFPISSSILTKLLIALNECSEWGRVAILNALARYVAKDDKESEHICERVVPQFQHVNGSVVLAAVKVIMIHMRGVRREDLIKQLVRKMAPPLVTLLSSPPEVQWVALRNINLLLQKRPDILSNEMRVFFCKYNDPLYVKVEKLDIMVRLAGENNVDALLSELKEYASEVDVDFVRKSIKAIGQTAIKIDAAAERCVHVLLDLIDTRVSYVVQEAVVVMKDIFRKYPSTYEGIIPTLCANLDELDEPEAKASLIWIIGEYANKIDNADELLGIFVDTFTEESYPVQLQTLTAVVKLFLKKPDSSQGIVQRILNTATKDCDSPDVRDRAYIYWRLLSTDPGAAKAVVLAQRPPISIPRTTVAPALLEELLGEVSSLASVYHKPEETFVGKGRVGAESLQRRTDAPDDRFSTQKALQTVAAGQQAENLLDFDDAPAVEGRPSGLAATEVLSHTPAAANLLAGTSSNPLDDLVSIFGAPATPAPPSANSHDIFGGLGVNSAFSSVGTGSLGSPAVQSPSVAVPPLQKNQQPEDDLLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3J2</accession>
    <name>A0ABQ8V3J2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_588126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="480" mass="53641" checksum="9B118CBD679B2617" modified="2025-10-08" version="1">MDYFSQYGGHEASSSINVPPRVESITDTSSSESASDTAGTSPFLNTHQLPLPNFSKTFTTETMQPTMQEEQNAFASTSAQPAYYPMPAAGYMSFQAPFSQNPSPPPAALSQTPSPVPIPNPSTSMPVPMPMPLPEFTPPVPVTNDVRDSGVDFGLGIRPPSQAASTAVIATEPPLFRARSLLGFAKSQSRLGFVRPRPPTVTTVTSESSSESDLDSDLNLIQPHYNTYDESTRALIEGLRPVMESCIEIVVRLIPTPQVSSAGRLIRLPLGREEAVCASMEGTLRHLWGCITLRPGCACPSEREQEAFPEGERGSDVCREFHEAFERKLRRFTTRMRTFHEQIDRPRRMHRSSFTERLLGWQDAFDQWINRFERLNAYLRLRLAHAHAKQIHLQLEDERAVAAQIRSHENSEAGSASGRRSSQRHRHHHELTIQQLREDYDLAKGALLEAHKRSAGLAWRRDGMGQLVRDFGNWTIRDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V462</accession>
    <name>A0ABQ8V462_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nucleoporin nup82</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_888262</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019321">
        <property type="entry name" value="Nucleoporin_Nup88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037700">
        <property type="entry name" value="NUP88/NUP82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13257:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13257">
        <property type="entry name" value="NUCLEOPORIN NUP84-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10168">
        <property type="entry name" value="Nup88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4473481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="842" mass="93819" checksum="54C98F39A232226D" modified="2025-10-08" version="1">MDNDDTLATLLNSHPIFSTPSKTFLPSHDSSLELSTNTLSSFKPANVSDNSATGRRQVMVLRDTDLILAAGKELRITSLSDAKSRRSHTKNYKTLHTPNIQFKIDQITLNSSGKLLAVAGAFQLAVVVLPRAGYSRLVPDTIDCKSIQIGQFYHGLDSAVPIAKIEWHPWGEAGSTLMVMTIDGKLREYDISVDTEEPQQVLTFVPEKKAGRSFVAEDASEREVVSFTLGKGKADWGPLTVYAVMRSGDVYSICPYMPQNSSIPSAYIHSLECFISAKQEFLAQETTTQANKNMSMLYDYQHKYVDALLKQLPPGTVFPAPSRSVLIHPPTIIKAPPARQGPFLLQPSPRMLDESEGGDATDIVYLSYSQTEETVSDAEDGVAENLDVVLITYQDGKIDVCLDVEKVEARWKSKNANHDLPMLAVYECIDLGLVSLLSSPSSAQGSHSALDLIQGNYPVFSVDPIHSDTIYVYHAFGVHALYLRPTLEILFSALHPSGTVSEFSELSSATAVQSILSTFSVERKSSNPVIALAIPDDVYLSYSIYILTSAMRITSFSLNPRPESPLLKSPADNNLVQSTSRHLELLGDTPPYTSLLGTEPWMPPSILTRNTGLPFNPRLSLPKDASQREFMLTPDTLRYLATVVTRYSDQVREVELAQHGAEGRAALQIQEVIRQTTKCRELLAIVERIKETRREASQDRIQKVQRGQKILLKRLDRMLQVMMEKASPELSEHETKWFDELKRLKEAVIGADRYDESSLSARIRTLEREYARLMPSLKALLEKERRRHNQAMTEHPGLGFSQAFEFGERSNHERTRLTDLEQDVIKLAAKLDVTLGKPPLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4M8</accession>
    <name>A0ABQ8V4M8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_850051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="192"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="221"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4472372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="933" mass="104233" checksum="CED86DFD95C2A3EA" modified="2025-10-08" version="1">MLYEEDRYRSRTNEIGYSSSDLHSTSSAAPSRSPSMQIDYRPSIQAHRDYPSRYQSDTYPKPPFPYSGQYPISTDGFSPIAPVYTEPHFQNVLDSHINNSLPAFAPARIDTRAQFPLSPRRDSHSLGVSIPYMLNHTQSTASTSHSWPSTEGGTTDADLPKKKPRREKPKIALAPDQPPTTQGRPRARVYVACIQCRNRKIRCDGVKPICYNCARKSNGGHDCNYDAAPRRRGPDKTPGARQRMARESQQDLDSSGIRRRRKPRETSPSRASETTPQTSQINNVAPPFYVNRLLSPEASSNQSMSPSYSASSTSFPSPLSDPPVYGGCSCHGLVHCPISQPYVSTRKQSLPFFDLLPAPGHTQLEQLSNTVEHGGAATRGWTLNIDDYSDESDNVTDIANEPSLRFSRKVWYEALCSLYASADTSNANRITHTDRAAISRSIARDLGFLFRASNYWFSFFHVPSFFGQFFDPVRRDTMQPSLILAALALSAFWQSSEIEQGRKGRIRALRLREEAQSVLEASFNAGSIDETLAQAAWLLALFEVCAHPDHSTSRSVSAIVMLDSIIRCLALTVLDAYDPNTSVFAAGQVPSINVRSSDGNVYIPHHERNASTSSGCSCLSRTLGKYWSKCVEHAPLWATTPAWDPTWSEAEIRKEASRRLCWAAISLAAGHVSYASANDSHIPDLHIADPSNFALLFSGESITSSLSLSPSAAKDTVWALYDRSFVLWHICARVRADTSMGDVEKGKFAVKAWLETDVIETALNKHTCAIEKAYIFQGREYLFNTRMCISFDFQRYIPLVNSGVSGIFHRTKAKEWLTHQAIVAERFMHGLHTITGNSNNLLARRPFFVFWFMSQVLRSLRLWHCDNSLIIALDVCKAFLPAIDYLSALWPCEEQRQRYMRLRERLDSACHIAGISTPPPANFALPDPSSRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V509</accession>
    <name>A0ABQ8V509_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_848028</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="71"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="181" mass="19586" checksum="8F110241F6F1F0F9" modified="2025-10-08" version="1">MPEPTTGKPLPPGMILGPDGKPCKVCTSFRHWKPAVATREQARSKTAASGAATTLAASSTLASSEIRRADCPPDSEELGRATWTFLHTTAAYYPERPSPAQRANMLTLIRSLPVLYPCTHCADDFGQDIKVNAPDVSGRVGLSKWLCERHNEVNKKLGKATFDCAKTDERWKDGPGDGSCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V553</accession>
    <name>A0ABQ8V553_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="512" mass="56811" checksum="FB2792D37EF7697C" modified="2025-10-08" version="1">MAAYTFSSSDGKTYKRNLHGFEALCNSYALHDFLLALTGSAEVQLRDESGIAVSQDTFASCLRAAWIQLRHRIPAVALRTVYQPEDASWTALYDVPAGSDDIDTWVAQTLVWRETKIDCLEHDLDEKWDGSLNGKIYAKVGKSSVLCSRRERSWCRSFSGPHGMFDGRMSMILLNELVGSLNDQIFKAMPVDLESIKWGEETARLASAGSVLTGLDMDSVPEPASTQTEEFVPFLPPSVENQVRTHDVTMRHVVFDNARTAALREKCRAHHTTITIAMDAIFAVAHVETILANAAVVGGAHYDSTVEAYTNAVHWFMPLSCKDQRPTWPSSSSINHPEGTTLFGTDGFPLQAKLETFRKAVGFSVDTKTFNSCDQESFWSSIIPHMAITHAAPQKNHAAYVHREREKQAICKSFNPSLMMVKSPIGSSIGHLEGLGLFTKYAPGSSSPTQVPRVLFRAHVSGPTMTNLYWQYDGKLNCSLLAAAKWNSPSEMDRMETTLRKWFDIAIGDKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5C0</accession>
    <name>A0ABQ8V5C0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_850659</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Required for assembly of cytochrome c oxidase (complex IV).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the COA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041752">
        <property type="entry name" value="Coa3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018628">
        <property type="entry name" value="Coa3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09813">
        <property type="entry name" value="Coa3_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c oxidase assembly factor 3 mitochondrial coiled-coil" evidence="11">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4471671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="189" mass="20546" checksum="F7459AC4D499D8CA" modified="2025-10-08" version="1">MNRKYVDPRLAAKTWRPKSGSMSPGLKRARAPFLVRNTLTGVLLGAFAVGVYTYSIRAVRQDDFADIDDETTAQREKERLAQLEKMRRESATVLTVGEEKDVMERAAKAVAREINGASLDASADVTSSSRASQPQSSPLLTEMAAQRSRRGVLVGLLDKTLPGALDPTKKTLVWGAPDVDNIGRVSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V674</accession>
    <name>A0ABQ8V674_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_702303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="93" mass="10906" checksum="0785679929B251E6" modified="2025-10-08" version="1" fragment="single">IPKPPGEVGRPNRGGYSLFLVLGWPKKKYDKVKNFINDLVEKHLDCGLPMSEQAREDLKKVRIKATEKFVFLKEYSGLWVTNDFIRNHLKYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6M9</accession>
    <name>A0ABQ8V6M9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_854474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="337"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="519" mass="58229" checksum="C9FDCB019268E849" modified="2025-10-08" version="1">MDNNSDANDGQQRSALPSSLIPHLYSAPQTSRDSFTRTTLSEQEEIEEDTELLEQQRSASPFALRPIPSEYPSESPPPASRRYPSSYSAYDHSVQPPSGPEMRLPPTAPAIRNESSYHNPRPAHLYNFSQIEMQQSYVAPTVGTSWREGEAGPSTITQRGHSNETRGRSTVGYVPPYRYMDQYQQQPQHRESYSRQDEPYHYGAYTQGHSLPQHGTDSFLSPMQAHRQVPEHMYGGNPSHPVNQNLYTFPASGQQPESHGSVARSWGPMIASSSTAAADYADSSYPSLPPLPHPSRYSTETEDDDGEYLPPERRNQKRKLENDEQEPGSRPKKTLIACDFCRGRKLRCDGTRPSCSNCKSRDDQVCVYQSHPRRRGPGKAPKGQRKKIASNRAETTTPASERSRASNEGSQHYSPSGDDFEVDTLPPDFRSQQQQQHLPPILPYPGPQGGMILPSSSQIPEGQSQFPPQSQDQGRFQQVHTRRGLRGSAVIPHPLYPDDGNAEHRSERSDSQWVRQRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V701</accession>
    <name>A0ABQ8V701_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_522339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="119" mass="13268" checksum="6878876B19ABBEAB" modified="2025-10-08" version="1">MTGLAKSAIPFAMREKGKRFLDLNDTLKLATSIAETRERKVQSTIGGRSQHTEAEIQAPLKTRKARNSAKLAGIKMQIASDRARLKKNKAKMRKQVLLGLTIVPEKRDSLPPKKRVSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V706</accession>
    <name>A0ABQ8V706_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022698">
        <property type="entry name" value="OrsD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12013">
        <property type="entry name" value="OrsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41512" checksum="AA96ABEBF24CC8E8" modified="2025-10-08" version="1">MPLLDHECAVKPPSHDGLIPNTPTICSQLSTIVETRRLDSSGNDEPSSLKTGQLQGSEMGDEGLGHVNDVEPSVVEKETGGDGDAEVVNEFNGDDELEDDEDELDEEDVPSEDEAPLVEGDDMDLDIASSSLSHAEILSSLSRFNVSVEPVYHLSICTECAIPIRLQHMYMHQKTKHFKSLTLPPELSFPSRAELESLLATLGADQPLEVPDGPIPRIQGVQIIQGLKCTTSGCSGKVFGAVEGRSRNLRVHQLQVHPQVALADRRSIQVPCQPLSANRRDRRFVEIKPTSASTSVSSRLIEKAAETCSLLEHEQVFTIASNEREKNAVFAQSRWDEVVNGVNLTLLMATISSSKRDVFVSFKRLKLIARELLSSEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7S5</accession>
    <name>A0ABQ8V7S5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Endoplasmic reticulum Ca-transporting P-type ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_897008</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07543">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057255">
        <property type="entry name" value="2TM_P5A-ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047820">
        <property type="entry name" value="P5A-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF7">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23143">
        <property type="entry name" value="2TM_P5A-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1050"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1090"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1171"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="domain" description="P5A-ATPase transmembrane helical hairpin" evidence="14">
        <location>
            <begin position="66"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="13">
        <location>
            <begin position="312"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4478915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1259" mass="139801" checksum="F317B5780BC7BEE6" modified="2025-10-08" version="1">MTILHIACLVTALHSKRQAPVALTQFLYSESKYGNRVLYTLPGYDYMASVTIDSPEVSRASLHKSLPWYTYLYTVPFLCLYPVLAYAYYVKYDEWLVSEEWTFLACVTLGSGHALSFLVTRWSTAAKAWVETSQVRSIEQADSIRIVPEVHRGKGEIVPLIKKDAKDVSSYTFNYQRDTYSVAKCSSDSVTFIKLPYPSSGNPSLNSFLKPQGPKFGLSSQTAEQLKELYGLNEFNIPIPSFTELFSEHATAPFFVFQIFCVALWCLDEYWYYSLFTLFMLVVFECTVVWQRVRTLTEFRTMSVKPYPIFTYRDAKWQEISSEGLLPGDIVSTTVPADILLLHGQVIVNEAMLSGESTPLVKEGVDLLVDELDRGVGLDVDGTHKGRVVFSGTKILQANGFSAADGVPEPSLKTPDNGCLGVVLRTGFGTAQGQLVRTMIFSTERVSANNMESFLFIGFLLIFAIAASAYVWIKGIERDLKKSKLLLDCVLIITSVVPPELPMELSLAVNASLVALSKYAIFCTEPFRIPFAGRVDVCCFDKTGTITAENLVLEGVTGVSEKDPMSLVNVREVARETTLCLAAAHALVRLDDGTIVGDPMEKTTLENMDWGVGKTHTKLSLNIRRRFQFSSALKRMCTVSTFQGPSVIGGTGGSTNRTLVAVKGAPETIKGMLDVVPERYDDIYKGYTRQGSRVLALAVKEMEFMNGEKINKLSRDTIESDLTFAGFLVFHCPLKPDAVAALRMLADSSHRCIMITGDNPLTAVHVAKTVEIVDREALILDLRENPRDERDLTWRTIDERKIIPVDPSAPLDMSLLSTYDICITGAAMSQLHTHPSWPLLVQHTYVYARVSPLQKEHILTSLKSLGYITLMAGDGTNDVGALKQAHIGVALLDGTPEDLQKIAERQKVERVKQVYESQLKISARFNQPPPPVPPAIAHLFPDAVQAQQKAAASQLEARKRNPMEKFDLAGITDKLAEMEGEDEVPKIKLGDASCAAPFTSKLSHVSAVTHIIRQGRCTLVATIQMYKILALNCLITAYSLSVQYLDGIKFGDYQVTITGMLMSVCFLCISRAKPVEQLSRERPLGNIFNLYVLLSVLLQFALHIATLIYITSLAHTFSPPDPATPIDLDAKFTPSLLNTAIYLLGLSQQVSTFAINFQGRPFREGIRENSALFYGLLGASAVAFSGSTDFLPEMNRWLQIVEMEGIFKVKLTLSMILDLGGCWVIEEVCKYVFAELEPKEMITRGRERREKRRAEEKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7X3</accession>
    <name>A0ABQ8V7X3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_888367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23563">
        <property type="entry name" value="TRIP13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="175"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4473532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="471" mass="52246" checksum="7DC1BA13F1EE27BE" modified="2025-10-08" version="1">MPPAPDIIMQSSQSTEPQRLRWPVHVEVRLKSRSTSRFETIRTHVQAWITSFDRINLSSSLDGWEDVPELAASVERIVTSESACPSQSLSVDEMALQIHVYQPCESDAFEEFSNSTNEDDDETMAATVRELPNRSWEGLWDSLIYEDNIKLKLLDYIHATLVFSDAEVDFNLVSWNRVVLLHGPPGTGKTSLCRALAQKLSIRLSQRYSHARLLEINSHSLFSKWFSESGKLVQRLFSSISELADEEDAFLVVLIDEVESLTAARASAMAGTEPSDGLRVVNALLTQLDKLKHRKNVLVMSTSNLVKAIDSAFVDRADIVQYVDLPPREAVYEILRTSLCEIINRGIVSSTNVPSLQEALIYERTAPAHSSTMISNGSDAHEKSKLLGLRLLTLATQCKAQKMSGRALRRLPVLALARYIGAGSIISSDNTEIKGRTKVNGSTGSGADIDMWLSGMESVVVDQGKQRETLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Y6</accession>
    <name>A0ABQ8V7Y6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_852269</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037850">
        <property type="entry name" value="RBBP5/Swd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040:SF1">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="461" mass="51179" checksum="B3D394055C3BD6BD" modified="2025-10-08" version="1">MNESLISPFNFSHPTAVQTSLYALGSFARFDPSGRFVGVGRFDGLATIWDLETKAAVRWLDGHVKAVTSLDWSRHSRYVLTSSKDWNVIVWDLASVCDPPQRHATIRCDAPVSSASFHPRNSQIILALLNTGEVYLVDLRPNHRSRTELYEPDGDEDGTEGQSSRRYAMTVARFDPSGKYVFVGTSGGYILVFNTRTKAMIARHRIAGGAGTIKGMDFAKNGRRLVTNSSDRTLRQFIVPHYPRSSETGGEIFIEQELEPTHRFNDPINKTAWHAVSYSPDGEWLAGGAADAANHKIYIWDISNDGQFASTLDGGREPLAHLHWHPSKASIASTTNQGNILIWHSPNAERWGAFAGGFEEVDENVEYEEREDEFDIEDEAEILRRKKEAEQDDVDIDTIDGETTDAHGHPALNGVHASNGSGGHGIGVGGNFDEDMKWADEDADDDLGVWKMKILMDDDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V830</accession>
    <name>A0ABQ8V830_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_852111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="519" mass="55758" checksum="E13B3D1C5225FD80" modified="2025-10-08" version="1">MVGNTFPYTPQDWLNDIKLAHSSGIDGFALNMGSDDWQPARVADAYAAAQTSSLDFKVFLSLDMSTLPCSTANDAASLRTLVTTYLSHPNQLRYTRGSSEQLPLVSTFAGESCKFGQASVVDGWRSQFTQHPDLQGKMTFVPSFFVAPNQMSQFQGVVDGTFNWNGGWPVELTTDSTGSSSNSLSSTLKNLLGVNTTTNAIGKFSNLLGTGETSSSSDTASGLLNLEDALSNFIGSTDSDSQFLNASIGNTSNNVYIAAVSPWFFTHFGKNSFNKNFLYLADQHLYSKRWESLIPAQVPLGTDSDLNATSTQPSISEQVDIVEIISWNDYGESHYVGPIEGALPTGSEVWTDGMNHTAWLSLTSYYASAFKAGTYPSVSSNEERVVVWSRTHPASADATSDTVGSVPGSELVLDAMWAVTLLSQPANVTLQIIPSSSNSSTESPLAQQTFPVPAGLSKLTIPISVPDTMDSVSMRTVVERENDTVMDLNAAQMGFAFVKTPQQFNFNAWVGCAGDGCVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V872</accession>
    <name>A0ABQ8V872_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_563544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045518037" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9114" checksum="D09DEC8578257E61" modified="2025-10-08" version="1">MITSDLFFPIILALFLLDPPTSLKPSGVFPPGLNLSSLTKSIPSKQFVSLPFIHSCCYYEPFRYLFKLVVIGPARWLPAVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V964</accession>
    <name>A0ABQ8V964_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DFP-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_923777</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="3">
        <location>
            <begin position="140"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4474762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="360" mass="40287" checksum="1B906084CD8856E6" modified="2025-10-08" version="1">MPESSSSFSAESYFATQPPPPGLEHDIEGVKEFVRRQQEKGRNIVLVTSGGTTVPLELNVAYGQLRPSVRFLDNFSAGTRGATSAEYFLKAGYAVLFMHRQFSLQPFSRHYSHSTNPFLDFLEIEPGVEERSSFTASGAGSKGSQICVTLDKRETLLEVLTVYKAVHAAGTLHTLTFVTVNDYLWLLRAVSQELSVMKRKAMYYLAAAVSDFFLPRQKMAKHKIQSGKGSLHIEMDQVPKILKPMVDNWTGKDGFVVSFKLETDPALLIPKAETSLQRYGHQVVIGNDLNRRKFEVVFISWKDALPSSSIDTADSSSSFAESWLRIDPYDHNKEIEEDIVAELVKRHEMWIAGGTTSIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9I7</accession>
    <name>A0ABQ8V9I7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vps5 C terminal like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_841447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="292"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4481806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="718" mass="79317" checksum="3336ED6CFA66D45A" modified="2025-10-08" version="1">MDGFDDLLAPSRSMLEDNPFNEDSNPFGSRRSGSPDPWASPFDHSHDAWTEDHHTQQSTEVEDYEPETPVSSSNISTEIPTEPVDSAGPGDPLDSATANVPSSDEEDNKPLGFKRARNVSLKASGFKESVDIPSEDTKEEEGRKDEGSAWKEEQAQDKGKGKEIEEVLEKAESLKGFSETATIRPNMIEEPELQRHPTPPTVTSSTSSLSGPSSPTAVWGPLSGQTSGWGEHEPYSQPEFDDGMSASAPVVSRNRDEDDSDDDKPLAQSLSMSPKSKKRSISNRPDDPSLPPLFTITVDDPQKVGDPIRSYVMYTVHTRTTSPLYQKSAFSVLRRYSDFLWLYNTLSFNNPGVVVPPVPEKNPLLFTNPILGSAGKKGYVGRFDEGFIRQRRFALEKCIQKIANHPVLCKDPDLKLFLESDTFALDIKHRKIDPGSPGPSSGIISSIGQTLTGTRFYETDDYFDSKRTYLDSLEAQLRSLVKSIDLVSKHRMEMAQAVSEFSDHVKELAEGGDFNTGLNVSGSSQAQQLSQTLMGLAEVERKAQDLHVLQSEQDMITVMGTVDEYARLIGSVRMAFSSRGRMYQAWKNADVDVIRVKQVHERNRGTSAYGGNSPTPGGSLSKGAGGALGHSLSQIAESEMRAAQAKRAFENTSRLCKAEMARFEEERVEDFRDALRAWLEGMIGRQSELITAWESYQQSLLRRSERVQNGKAPSISAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9L8</accession>
    <name>A0ABQ8V9L8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ectomycorrhiza-regulated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_772315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="109"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4478876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="19846" checksum="63C016B79F455866" modified="2025-10-08" version="1">MSSPGYSTIHAGRSNYGPGPTRTAPTITSHPPPLRSASTRRYSPDALLGPDAPTQPRNYVTPSATSRKEIPTYFIKQQRRPSPPQATGMSEDEDDELTEEPPAENATDQEKIDYKRRQNTLAARRSRRRKLMYTQQLEATVENLTREKDVWRTRALTLRQLLRSHNIPCPEFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAV5</accession>
    <name>A0ABQ8VAV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_772066</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="99"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4479421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="197" mass="21232" checksum="2279206F438E60B6" modified="2025-10-08" version="1">MSSSSDSHTTFTSPYTHNVVGGSASNYIKKVLDDLVHIPSRRPPQKLFASTIMDSMILADVCIGSMAEEPARLEGKVVIQLVVNEGSSVYSEHMLNLANTVHGGCIAYFVDFCSSLALVALDVHQNNDYTLSVSQALNIVFHSPAALGETIRIVNMSVSSGGRSATGRTEIWNDSHKRIVASGTHIKMLPSKSKVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB96</accession>
    <name>A0ABQ8VB96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_868370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045907164" evidence="2">
        <location>
            <begin position="19"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4485086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="31417" checksum="4097269333204D36" modified="2025-10-08" version="1">MHISILAIPFALTFLAAAAPFYQPRAGHSEQSNTKASKSGSTSPSTNHNSCTPLTTITRSKTSHKSKRIDAQVQHPLGRSDAVLFHGTYREDHAAELQSEVDLSSIKHGDLHDVAVSGVDGGFYLTDSLLAAAQFACRNLEAKAYVLEYKWTGANLPVKEYQKGAEFTAFLDYDKHAEAPSRNAALDQIMTDNDMITGPMTDKYADAFLTPYFRQYAVIKQRAATNNLKYTSTYEVPCTAVPVGKNLYAEYYTASQKSSPHFDQLVKLLMQCEPGIGHWQEAVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC98</accession>
    <name>A0ABQ8VC98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_499603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="539" mass="57747" checksum="F4C6E05A04A2FA17" modified="2025-10-08" version="1">MKNASLPAGALPVHPVNIVLPLPLSLTPSPTKLGFPFGDPEHRTPLRRRRSSAFAAIKNWTLTVQPGSPAPNSPHKSISVSPGRRSSISIARDLISRKTSISHNRAQSNSSVAHLVELETPGISNYKQPQFDLTDLGYTSIFVSRIYTPSTPSPFLLRDPYPSNSRKQISVQKETPKGLKRIKSLGMLKRNRRKSVSAAAVDVQEPTSRPRSHSRSKSALVSAHSKKSSTHPPLPPTLASELLLRQFTDGGSLETHAKRVMEEQARLAAPAGFHKGTALPVGTIYRDENGLIWHDEDERLEREALLSPHTPESPAREWITFNSTGNSPVLPGMALGVGTAEPEKRRGSLASVTSSLSMSSNDIVTPADGSSYFLHSLQPSYAGPPSPLSGFGSTRVPVSPTSTLSTITGMAAATGSMAQNRRTRRRPAPLRLNAPSASNAFDDSFIPSPRAMAVASIAPTGRRRSSTGAMGLSAPPACTEFTSTSSASKIEGDATMKENFKADDLDSASLTTMRSKKVLGMKKISKLNLKSMKSLFGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCU4</accession>
    <name>A0ABQ8VCU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="16">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_836338</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="16"/>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 16" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="17">
        <location>
            <begin position="9"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4488624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="345" mass="39002" checksum="F8B947BD593B1250" modified="2025-10-08" version="1">MSPDLSFIAAPMVNQSDFPFRRIAARYGATTVYTQMLSPERLIHDQEYLESHRRDLQYRIEESISTVVQLCGNNAEEIVEAGRKIQDLCDAIDLNLGCPQEVARDEHFGAYLLGQKDWPIVENIVSCMAQSFTVLVSTKIRLCQPSTKTVEFAERLQASGSSWITLHARTVSSRRRRQGAADLSEVKKLKESERLTIPVVSNGNVRVFDDLAKNLDYTGADGLMVGETLLGNPCLFSNDVLPDPVDISLEYLDICRLYPGVATLKTIQTHIRHFIDFQCTRRPWFKKLRVALNACTDLDDIEHLLRVKVPRWRGMTMKSAEEGSEHERDGIDLADSGVLWHLPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCV3</accession>
    <name>A0ABQ8VCV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">trimethyllysine dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Epsilon-trimethyllysine 2-oxoglutarate dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">TML hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">TML-alpha-ketoglutarate dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_844015</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:14181"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:58100"/>
            <dbReference type="ChEBI" id="CHEBI:141499"/>
            <dbReference type="EC" id="1.14.11.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; carnitine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.8" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF51">
        <property type="entry name" value="TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0124">Carnitine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="18">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="17">
        <location>
            <begin position="100"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="17">
        <location>
            <begin position="284"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="225"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4478513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="448" mass="49631" checksum="4AF7F84FC8DDDC10" modified="2025-10-08" version="1" fragment="single">HHIWLRDHCRCPTCLHPKTMQRLLNTFQIPPDIKPIKVESSLQGLRVVWPAHEHTEHGEHESVYSWEWLKENSYDPRIEPEDKETKKILWNARISQSPPTVSYNDVAKPGEEGEQALYKWLTNIDTFGFSFITDVPENAASTESLVRKISFIRETHYGGFWEFTSNLAKGDTAYTNIALGAHTDNTYFTDPCGLQLFHLLEHSASESSSSTTYTSTTYPNTKLPNLYASSASPTSNDTQITSNPNSANASSSSSAFTPSSLSSPATQGADATVSSSYPASSAPNSSLGGQTLLIDGFYVASILRSLYPSAYRLLSEIRIPAHAAGERDSAGIFSTGEGYTVFSHNASGELTQVRWNNDDRSVLSSISPSLVEEFYAALRTFHSLLTTPDSEFLIQLTPGTAVIVDNHRVLHGRTAFVGNRRMCGAYIGKDEWKAKLRGLREKYEGKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCV6</accession>
    <name>A0ABQ8VCV6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_404142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="13"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="167" mass="19903" checksum="8C723F029A81FBF6" modified="2025-10-08" version="1">MADFYATEHSTKDNTIVHRSDNIIAYIIETPSKILQLHHERSTIFRGPYREPIGFIEFHGFHDNIVEIRGRSFLPKRARESSHFSESKEFIASDGRAYKWKFYSHEVWELLTQDGTHTLVARYDRKNISIYPQALHIADEVMVTLFYMRQYKKKKDDERRRDHVGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDT9</accession>
    <name>A0ABQ8VDT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_982945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4479901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="48015" checksum="FC67439FC6D45399" modified="2025-10-08" version="1">MASSFQYPTTSLSKELTQLIPIEIYEYIISFLDHSPTSKSCSLTCRSWLQASWKRLFAGTILMVHRENIDDLLEIVERDAHFMTIIRFVRGLYLEQGGSLRLPTWSDSEERDKFKEAFQFDEYLPLLVGFKSVRMLKLGWIRGDTGPPTALSLQNNFGVGVTALELNSVILSSPSQFFEILRALPQLTSLMLVGLKFNSGRPSEDAREAPGMTLVDTPKPPQLQELYCNVTEDIADFIFSWFAFHGPIPIETVAVGLFNGSTNSKVSRFLCESGSTIDTVKIWDAYSQDDFDLSPCVKMRTLRMGWIHLSSSSPPGSETFVTDVLKTVSSPYLEEITVVLQILVSNSPGVESDLGAFDWRGLMSVLQQPHFRNLRKFCLSVSSHTRVVKQALMKHINPVIASGKLPFNPDVFHVVAWSRTEFRGHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEA0</accession>
    <name>A0ABQ8VEA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CNH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_445814</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04435">
        <property type="entry name" value="DEP_fRom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF2">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="4">
        <location>
            <begin position="582"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="969"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="457"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="862"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="862"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1363" mass="153704" checksum="1570AC79078849EA" modified="2025-10-08" version="1">MDKPMGPRQPPAPDKRNAAYESIFGRPSASHHHQSPVPTVQPPYPPQTNYYYQQQPQNYQQNAVDRRTSFQQYHHSPSLYTNPTYNSSNIPPNAYPRYTPSSYNYTPSLAPPSVSIRARSIHSSTNGPGIIAPKPEEPPDPSLEALTKSGLTPAQAYQAQIYRNSTPSSLPAVESDDGRLGIDFAAESNSSDQSTDDSSELPWARKESPRTMSSLPQRNSTANISHNRHSHASTNHSLHVDTASAQSIRSSVASTSPSSFSLADNNSLSMETATTSTFVGTSTGRRSSESAHIHRVTGNARREKSAQDRSMSMSAATNSMRAVLASRVPIPGLPEGRHSPISIKTHTRKTPIVYPALLSRVAEAFRDRIQLADRLKDGLTYKNAFDGREAVDKIAYIIKTTDRNLALLLGRALDAQKFFHDVTYDHRLRDSANELYQFRTKLPSPFVSGELPNVNATSSELPSFQTATESPVEGEPSSPSPSVNQSRPRKGSFSSDEVELPSGVFTLLTDCYSPTCSRDQLCYSIACPRRLEQQARLNMKPQPGLSKQISKESLNDAPDDGTLWIHSVPQEIVNSVSDTEKKRQEAINEVIYTERDFVRDMEYLRDIWIKRLQESDVIPEDRRTAFLEQVFWNVFDIIAVNIRLRDALVKRQKQYAVVEKIGDILLDAVPHFNNPFVSYGSHQLYGKYEFEKEKNSNPAFAQFVEVTERLPESRKLELNAYLTKPTTRLARYPLLLEAVLKHTPEDNPDKTTLPQVVSVIREILGRVNTASGQAENRFNLIQLDGQLQWRPGEEVPLRLREEGREMIYKGPLNKRDGELQVYLFDHALLFTKVVKTKQHEFYKVYRPPIPLELLLVTASDDASPNGNGHNTLRGNRRQGLVKKNSFSRDSRSSPNFTVPPVHVKTDAKGQFWINFVHLGRKYYNLVLWANSNLNQKKWLENIYKQQQAIKERSNIFETVSLSEGFFNNPNKVNCAAPFSGGRKIAYGTDDGVYFGDLREVNKDPVKVLGLLDVTQIDVLEDYQLLIVLSERSVITFPLEALDPIDPLAGLKRAKRITSHTSFFKTGYCLGRMLVCIVKSSQLSSTFKTLEPIDQGTRGRAKPTFRKLLQGGNDTLKLFREFYIPVESSSIHYLKTKLCVGCSRGFEIVDLETLDTQGLLDPNDESLDFVRKRDNLRPMAIYRIQNEFLLCYDEFAFYVNKNGRRSRKEFMVFWEGVPTGFALHEPYVLAFEPTFVEIRHIETGLMTQVIQGSNLRLLFADNPPSMTGAGSQANSWGIPNPGMYQPGYEANPYNGYHQPYRPGYGGYGGPPTLPMQYPMHPRQQGYVRDEILMVSDDRVFALRTNYAEPQHLVSDNASMISMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF12</accession>
    <name>A0ABQ8VF12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GPN-loop GTPase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_841153</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17872">
        <property type="entry name" value="GPN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030228">
        <property type="entry name" value="Gpn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF7">
        <property type="entry name" value="GPN-LOOP GTPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4482693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="289" mass="32725" checksum="9312BD908673E526" modified="2025-10-08" version="1">MRYAVLVTGPAGAGKSTFAKSFMTHLAASKRTGHLVNLDPAADPSSFEYEPTIDIRDLISLEDVMSELEYGPNGGIVYCFEYLLQNMDWLEEELGGYEDDYLIIDCPGQIELYTHHPFIPTLVQHLSRMDIRTCATYLIESQFMEDKYKFFSGVLSAMSAMVNLEIPWINIMSKMDLITLNPEDPSGGARNGLRKKKDIARYLDPDPLLIATTRGDKSDKTNPRFHALNQAIVQLIEDHPLVSFLPLDLTDTDSLEYVISHIDYTMQYGESEEPKEPHDLDEGDFQDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFL3</accession>
    <name>A0ABQ8VFL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase</fullName>
            <ecNumber evidence="4">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_765178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="5">
        <location>
            <begin position="14"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4492434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="440" mass="46339" checksum="151DD903D6D4D68D" modified="2025-10-08" version="1">MSASSDVLIIGAGLAGLSAAYNLSKAGKTVQVVEARDRIGGRAWTDYSFGFPVELGCMAIHGYNQGNPVLGYAKTLGLETKLLPASPGTLFTKDGPLDADLTRRLHTNIFLAMSHMNKVTSEPLSDSSSAADILLSSSSPLYTGLSETEKEKATALARAAEIGWGISLEEASAHWSGWASGVAFAGSDGIVVGGYGKLVAALRAAAEETGKASFVLNAHVSKVDKTNDGRIQIHTSNGQVYNGRAALSTIPLGTLKKVTDDFFDPPLPARKSSVISRTAVGILEKLGLLYDSLWWDPTAGPFTILSEPGTFLAIPISSSPPCLHVLVPHGLTGLSADTIHNVLSQAIAPEKTVPKPIKAIASRWKDDELSFGATSSPVRVGEGRSPLDFAELARPVWGGLLGFAGEATELDHRGSVPGAILSGEREARRIEALLDWQYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFU9</accession>
    <name>A0ABQ8VFU9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Arabinogalactan endo-beta-1,4-galactanase</fullName>
            <ecNumber evidence="3 6">3.2.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_380214</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>The enzyme specifically hydrolyzes (1-&gt;4)-beta-D-galactosidic linkages in type I arabinogalactans.</text>
            <dbReference type="EC" id="3.2.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.89" evidence="3 6"/>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011683">
        <property type="entry name" value="Glyco_hydro_53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983:SF1">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07745">
        <property type="entry name" value="Glyco_hydro_53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045003371" description="Arabinogalactan endo-beta-1,4-galactanase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="352" mass="37620" checksum="55A993D1DAC81E87" modified="2025-10-08" version="1">MLSQNHWQSLVIFIASLPLAYCLTYHGADYSSLVNLENSGITYKDSGTSEKFDTILANNGVNLARIRIWTSTNDADYSLDYGLALAKRAVAAGMSLLIDLHYSDTWADPGDQATPSSWPTDLDGLNTEIYDYTNSLVTSFADQGTPIDFLQIGNEINSGILFPTGEISANGYSPLSQLLHSAANGAHDASDTVKIVVHLANGWDGSAMSSFYEQIFIQGEFATTDFDVMGFSFYPFYDAAATYSALQSSLDNLVATYGKDVMVVETDWPSSGSCSGVTLSEDFAISTSGQESWVSGITEILAGLSDGHGLGVVYWEPGWIGNDGLGSACSSNLVVDDSGNTLASIDLFSADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG31</accession>
    <name>A0ABQ8VG31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_832552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="74" mass="8748" checksum="47F1ADA3ADD48EFF" modified="2025-10-08" version="1" fragment="single">MTIELSLLTHCFTYVLLMFTTNPGRWALVGRRVVYSYISCSYLLYFLSFDLVYSTWFSPELCLFPLSLRHHNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG54</accession>
    <name>A0ABQ8VG54_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_333413</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="14"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4493214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="36127" checksum="AC0A95FA62EB0D0C" modified="2025-10-08" version="1">MSTSVATFTGPSINIDCSADGRPVKRPRKDHQPATHSEGMHQEFTVEPSSSQNHVFISETLTSKKQGGKKVPLSCCECRRLKLRCDRTFPCGSCKKRGVSDICPDGVLVSGKGTRFILANTEQLHSKIQEMSEHIRRLEEALEGTSSPSNPHPLLQPDMLNVKSTMQLYGVAQPKHDGSSIPVSAERTIDHDLNSDIEPNWTDAMSSVAAGKRRDDRMEAEIQRLNHAFPLGDGRTSLESSLSLREYIRCQLPSRQESAYLWEQMRANVSWQYVPSDYILLGSDELLTLDATSIQILVSFLIFFTIAIVPPWKSSVPDVLHCFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGR3</accession>
    <name>A0ABQ8VGR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_951781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="867"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="931"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1027" mass="117573" checksum="D255B336AF0C6039" modified="2025-10-08" version="1">MEEHVAKDMSDLLFARSGVSLSPEEVQMSLQLAIRRKMGRIDDVQAPNAMNDVSEASEIRQVTDMQMNANDIETNKLEIASHLKAHINTFLDNYDSQMVKLASNQIQIPLWKPEFPNIDTELREFIWDLNIPRARAPNDHLPDMLLHNLGRFQDNKELVERLDVLFGRSTHKCVIIVMNELRLVYELPKGFRKYFRFWEDQVNPRTFMLSMGRIPHVSPGIPSWFIGLDACDIGDGAAHKESSPCALTTEQDCLKARFKGNNLLDSFRSTPEGERYGMLLEANKQVVTVELLALVLARLHVLQRYVATLHKMRENTSQMFHKRQWLYLQLHPEILTLTDGKPKDIFIELIQHITELFTEAKLASNNLQIEVMYILLQEVLSNISDTLGSKFDVAVDECCFIFTGTGLSRDIISEALSSVISKPGFTVDVNETGAFDDATVQLEYLKEFFPPSIWKDREFEQLRRRIFHWLRGRFTAEYISVALQNGYQHLDKVLNEYVGQMTNIRPADYDGPETTSKKIVWPVRGFAFEELDAEMRERIKMISHEYLFSSKLATDLGENERRYVEYGLARFTNSPGSPKQYILIDEPLVLLACSMWFNNQPQRCGTNLYQTLASRIRDHNASSGRNGFEEFICFYLQHVFSKPRKLNEVFQFLGEDIKDKNPQNTKPTIGQKLATLVTLHIFDNGKEARLVEGKINLVGKPSLLGPIGQAIESGASESLLNWVELKSHTAFCFPMPAMGPDIMCFLKLQDEFATPDEYTYICLAIQCKFYQRRTLPSMTLLEAIATITPNHFFQRRNESNATTETGAKQQGTMDMNKEDVRNRFLRALSELPRKDPLAGRYGIVRVICGFPVNINISKAFDIKEKDDKETASTRVKMATSRRIDPDGSDRHPLGQLDTEMLESITEIFHPTKILDVIRKKAYDEIKGKKAEPTLTLNSPGVGDLPEPEPEPQARLPRRNKVNIQKAEAIRKLTFGVRKGIDRTMTSTLASRKDRIDSRATESVLATLRADHEHWGQRVELKRKHEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHS5</accession>
    <name>A0ABQ8VHS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gated mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_921013</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="entry name" value="Large-conductance mechanosensitive channel, MscL, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266:SF2">
        <property type="entry name" value="LARGE-CONDUCTANCE MECHANOSENSITIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="MECHANOSENSITIVE CHANNEL MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="Gated mechanosensitive channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4487478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="20270" checksum="A6330B776215D6F5" modified="2025-10-08" version="1">MSHESFLEHAPSVFRKAKSVWSDFIDFVASDNVLQVAVGLIIANGFTKVVQSLVSDILLPPIALLPFIDRNFEEKFVVLRKGPHANQTLPHSAGYNTLDQAAADGAVVLAYGQFITNVANFLALGVFLYLIARVYAVFTHKTIISHTVRCAYCRKYVSEKAKRCFNCTSWLDGREERETSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI40</accession>
    <name>A0ABQ8VI40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporter NIPA-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_829206</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF92">
        <property type="entry name" value="SPICHTHYIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="482"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="543"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="602"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="642"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="663"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="691" mass="73479" checksum="4960DE80E5B7CCC6" modified="2025-10-08" version="1">MSSSSSTSSATSTAAAATSSVASGTISVGSNLKIVGIILAIASGCLIGSSFVFKKKGLLRAQAGKVAGEGVGYLKSPLWWIGMTMMIMGELCNFAAYAFVEAIVVTPLGALSVVICAILSSIFLQEKLTFFGWLGCGLCIIGSVIIALNGPSENSVGQIKDFQKLFLAPGFLSYASVLIATALAIIFYFAPRYGKKSMLWYIFVCSMIGGISVSVTTGLGAAIVTTAEGDNQFKYWFIYFLMGFVAITLITEVYYLNVALALFNTAMVTPTYYVIFTFFSILTTIVLFQGLSASVSSIITLVMGFLVICFGITILQMSKVDPENLTKLDRRSTILLQASREHTAGFDEKDVLAVEDPGMDTLRGSFGAVGSIIRARSARRMSQSRGGSRPGSYSTRPAGAMAPYDPPRGQAWLSPRNSTNTEYLGGLKRHQLYDAPVPPGSPSLTGATRGDDASSISSAGRDSQMMNKRPTIKFDTQDVVHQYHPTGQTPGGTRGDPTAIHGHRATATSPGIPGLPGQHNDVNPLSIPPSPSAASASRDFLSESPTDTEGPSASTLSQIISLPPLPPRSPGHENIPYSAPPTSILPRLQQGRKDSRDLFNDTPSTTTLLSFPSVTDSARSWDGDEESSHSSTTRGRTARKYPKGDKETDREESVSLWQRDGDSVDGDGDETDMAPHGGIRLVTSKGGSSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI68</accession>
    <name>A0ABQ8VI68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cu-oxidase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_767377</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13903">
        <property type="entry name" value="CuRO_3_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047482560" evidence="7">
        <location>
            <begin position="20"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="34"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="163"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="376"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4489032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="524" mass="56765" checksum="AC257ED28CE133E4" modified="2025-10-08" version="1">MKLLASTVLAALLALPAFSDTIPITLDIVNADGAPDGFSRSMVTANGTYPGPLITASKGDTLVVTVNNLLDDPTMRLSTSLDFDGILVNTGNSFDEGSSFVTTCPIAPNASYTYVVPLVNNQTGTFWYHSQLSVQYVDGLRGALIVYDPDDPLKDLYDVDDENTIWQVGDWWHNSTLPMLAGYVATGIVPVSDSGTFNGVGRFNGGPDVPFFVVDVVQGTRYRFRIINTSARNVFTMSVDSHNMTIIETDGMPTSPMTVNSLDLLAGQRYSVVVEANQPVANYWINAPYVGGSPARNLNQNATLSRAILRYQGAPEEEPTSPMSLGPADEELNALVEANLRPLVASPAPEADINITLNLVVTAGKAQWNVNNVSYLAPEVPTLVKILDGANSTDDFNVTENTFILPANKIVQVIFPPSEDDEEHPFHLHGNNFWLIKSNSSDEINTENPIKRDVAGVGSTGTIMRFSTANPGPWFFHCHIFWHLQAGLATVMASGLNETRAEVHPTQAWTALCPAYDALSPDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIE7</accession>
    <name>A0ABQ8VIE7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_920214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="22700" checksum="A31CE4E9431BF99A" modified="2025-10-08" version="1">MIPDGGSDKTPPNLVSSHRKFRTTVPPKILLLGIIRGPSLPQEEITWIVQIRLEKCDQGTLSVVARGHKVSTGHPCVQYFLSPSLRPASSQRWFVDLPVCFSLDSVFLPVRKYLLLDRFSGVLLNKPIAYSTSHPSSPLPALRLFAMWYRILPSTFSPSQLSSICLLFSTVLLSVSAIAIPSGSVSASQQHQKQNGESTTSSKYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIR7</accession>
    <name>A0ABQ8VIR7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_918670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="38218" checksum="D60235711F8B0F0D" modified="2025-10-08" version="1">MPSLVYPHRPFTFHIATSWAGKPSTGDDRVTDDQPFPLESPIGRWREVMLDRDIGLKKKRRGKDWVQDAGEDFFYVQEMRNGSGAAFGLADGVGGWIENGVNPALFSQSLMYHAHRYSRNAWAGEPEIDPTLDYEEREQVEGWELTPYHCLDLALGGVLRERYVQAGSSTACLLTLNSSSGLLRSANLGDSGYSIIRSSNVIYKEKVQTHFFNCPKQLTKLPANPGRKFARVCIDSPKEANTHSINLRDGDLVVAYTDGFSDNVFPSEMLSICSLAGRKDATEDEQVQSMADNLILYARQCMMDRRRISPFEREAAREGMFFRGGKIDDVTVVVALVRETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJG5</accession>
    <name>A0ABQ8VJG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_300686</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="34431" checksum="6066FA93647BBCFB" modified="2025-10-08" version="1">MVSTIEPKSRFRRLVCSVAQKFHSHHHNGRSGRSESVAGSANSTVTALRGKVALITGSSKSTGASIARALAAQGASVVINYAKDSRSAEEVAQQINLSLNSTSVSLSLTSMNHQGDGRNDVEVPRQQQQQAIAVKADSSTISGGHYLLQETLRVFRRLDILVLNAGLMGSRTLSEIDESFFDAHFDFNVKAPLFLVKEAAEVMVRPGGRIIFLSTSLTTASIPSALLPNALCYVASKGAVEQVARVLSKDLGTQGFTVNTVALGPVDTALFRAGTSQHVISSIAAQVPSHRIAEPDDIAPVVAFLASPAAQWVNGQIIGVNGGYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJH5</accession>
    <name>A0ABQ8VJH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_825961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="86" mass="9471" checksum="86DA8474FDB85D84" modified="2025-10-08" version="1">MVLTESRQSDQLMLRFNIGVNIVLNGTIHVPEDVAELIAALLLGLLSSVSTFRFISHQRLACRHDSTGLYMQSVNSETVLSACNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJP4</accession>
    <name>A0ABQ8VJP4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M24, structural domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_826679</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="7">
        <location>
            <begin position="42"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="6">
        <location>
            <begin position="376"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="8">
        <location>
            <begin position="605"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4496486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="667" mass="74639" checksum="C9E5577A00740E0F" modified="2025-10-08" version="1">MTFFHLSLLSSRRTITVLRASYQQRLFTSSPQENMTIQTTERLVKLRELMKKPENNVDAYVVPSEDQHGSEYIASCDERRAWISGFNGSAGCAIITLDKALMFTDGRYFLQASQQMDRNWELMKQGLPGVPTWQDYLTNNLPASSRIGIDPTLITENDSKSLSSSRNEAELKGSQTLVPLTTNLVDVIWGSDRPPRPKHAVVPLDEKYSGESVTSKLNRLASAVSSNTPAPLAFVLTALDDIAWLFNLRGSDIAYNPVFFSYAVVHFQPSEASDSSKNTTAVLFLQRDAIERVADLKYALGSQVEIRPYEAIWEYLKDLGNQVRSTFADKGQRKLVLIPDKASLAIVQAVGVDISNIAPSPITVLKAIKNSTELEGFRQSHIRDGIALARYFSWLEEKLGEEGNEITEWEGAEQLEKFRSELPLFKGLSFDTISSTGPNGAIIHYSPNPKDCAVIKRDQIYLCDSGAQFLDGTTDVTRTWHFGTPTEEEKRTATRVLQGHIAIDSAIFPNGTTGYIIDSWARKALWMDGLDFRHGTGHGVGHYLNVHEGPHGIGTRITSNASPLKAGMIVTNEPGYYADGKYGVRIENVLIINEVETPWNFGDKGFLSFECVTMCPIQTKLVDQSLISVDEKRWLNNYNHKVWEKISPLLRNDDRALKWLEKECQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJU6</accession>
    <name>A0ABQ8VJU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_793160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF82">
        <property type="entry name" value="THO COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="116"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="221"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4496668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="30312" checksum="85BFD95F13C61DAD" modified="2025-10-08" version="1">MASLLERMNVSNSGSGPVRSTKMGNTSRSNAPYARSARGDVDSAWSHDLYAQHNSLSARLNLPASKPTLPPDATHASKSLAQKAFRDALSFSAPSTSRGARGGEELNIKGAGSSGNVVEVSGLVDGTTAEDVSAIFKRCGDILQSKLISRRNEEVRIRITFKLAASAAEAVKVFNGVPADGKTLSVAVVGATSAGTSLLGRFGKDGLGLVRQEGSVDVLMDSDDTLSGSKMRSDALTSDPRAQVLVAPPGADPKDYIQAPARGRGGRGRGRGGRRGGGGGRERDRDRMDMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJV5</accession>
    <name>A0ABQ8VJV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AMP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_761366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="43"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="481"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4496672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="585" mass="64254" checksum="BC805A2E1786C65D" modified="2025-10-08" version="1">MAPRIYYSSYPSVPLHTRSIFTHLLSVDPSNGNIGGFPAQEKVFVDAATGISISRRDLRTLSLKFGYGLRHDPRVKARRGDVVLVFSPNSLQYPVYILGAIAAGMCCTLTNNAYTARELQHQYIDSGATMIITTSENLSVALEMLIVGLGLSQADAESRIIISRNSLAWASGLVSSRSEGEATRDLITFDQLLGIGELQNEEEFDGESAQETALLCYSSGTTGQPKGVETTHQNLTTATETIDLVLGYKAGDQLLIFLPFYHIYGAVSGLLFPIFCGTTTVIMARFDLIDFCVAVERFRITAVLVVPPVMLAIARHPAIDKFDLSSIWLLFSSAAPVSPTLIKEAKKRLLAKRKPEETLYITEGYGMTECSPASHILPLDSSVLKMGSVGVLLPNYQARLVADDSGETEVDAEEGIPGELWLKGPSVMKGYLNNLTANKDSFTADRWYKTGDICVRDKEGFYFIVDRKKELIKYKVLPPAELESVLITHPEVADAAVIGVHNEKDMTELPRAYVVHPQPAKISTPESKKAFEKSVAKWMESKVARHKYLRGGVVAIGEIPRSAAGKILRRELRAMAKRDSVQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM89</accession>
    <name>A0ABQ8VM89_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045711203" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30783" checksum="0C72238BECDFCB03" modified="2025-10-08" version="1">MKRCTFLLLLLWLVQRSLASFSSELEYDSDWEHLTRSRRRTPVYAGAHNNPERHQSFYEDNQVVSEPHICAARNVELSTNTSLRKADSGAGQNMESEKRRGPPAMVFVDDSDDDLLILKPPGEVGRPNRGGYSLYPVLGWPKKKYDKVKDFINDMVEQHMNCELPMTAQCHTDVKKVQIEAVAKFEFLKEYSGLWVVDDFIRNHLKYQKSVLKKEKLEKIAADARPATSIAAAGASTTSTSTTQTSTTTALDPTLTPDSNSRSSSGRRRGNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMR9</accession>
    <name>A0ABQ8VMR9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_820700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="330"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="432"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="597"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="671" mass="74408" checksum="8AADCC96AF0DB0BD" modified="2025-10-08" version="1">MVSRKSTKTAKLTYAERIVCAMHALQKSQRRGGFHSASIKAQVRKDAEERNDKLGPQWPTWVMKALNRLNENGLLSRNVDNPAHFEMSPASKKILKESERKLPVVGPHGEEFLAKHLFRATAGKKRPAESGIDSTPTKRPRATRTFKESAPRSPWLKKRKAELVEEIERLQRERLQRERLQSLQIPSRSPSPLTDLDDDEDVIFDMDEHNVPSQSHSSTPELPTRPSTPVEPDQMSFPSTPVRLHSSLTRSRPLLQVTRTHSGSYIANGRPTPDPPEPADRDIHHGLSLIMGNALSDNECHSPVISRPNGLVTPGPTPARTVSSHGSMHSQTMANELARITEENKQLRAVEATQASDIDNLNSEVQSLRQMNIDNKERVTTLLVEASTLQAALAQSTQRCSSLDAQLSAGTAEIASLQVSLDTKNQQITDFVQKLQDTNATLEARTQDLNSAQLVAAKLENDLAAVISQLDNREVELTSQLVASKRSMEDTSSTLQQKITELSNLHEDLRKAQTSVTTYQEELEAHTAAHAAEIGECNATIDSLRASLSSADTTAVDLRSKIGLLTETCTQLQSKLEQSASDRSRLGEELAVERLHSATIRGELDQALSRIHEAEQEMGEVESLRSEDAATIMKLRNTIERIHAAQMEQWAEINQDVTQASPAPRRPRFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNG8</accession>
    <name>A0ABQ8VNG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_174468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23978" checksum="5A846E9695870817" modified="2025-10-08" version="1">MFSKATTKHYIQLLLCNFLGTLFILLSLDLNVTTATHSQLLVTLPFLLFPPTSVAIAVMLLRSWAYSNPERSTPLPQYSPEVMNHEDIFANKMVLVGFFHVLMVLSRVLALASGSCIVFFIGANDTLNAPLNQSCWASFGLCWFWLSIITFGHCLLVHKINKNHWGLFGLLFDASFFAIKFTVVIFSATTNLFEAIRGSLKHFQAHWGGRKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNI9</accession>
    <name>A0ABQ8VNI9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_820349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="34567" checksum="4D3DE26B53FFC2A1" modified="2025-10-08" version="1">MLTHRGFSAWIEVDGQAIPEYLVAVNSKLNQVSCWIPSEESQVFSVHWSDAGGKVDTCSFITLDGVVVPGRFLLGSGTTSRSGVRTSKDTEAPFVFKKSQGGTTLSTASKSEAGMVTLKIKRVDRVSPRPANAYQDLTKIAPAQPNVGDLCAGFGAECKSHEQSPFTWAIKPHDASQIKSKKIATYVSFVFRYRSKEFLQSQGIMEPHQVPDTPSPSIPNRLRRDPVRRIASAPASAAPPTPSPTPPLRLSSKDNPKPYIASPYPLRRPTVDTRRTASWRSTTAAPGSASSHALVYFEYSPDSAVTKDGSDLEYHASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPV3</accession>
    <name>A0ABQ8VPV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MRPL25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="30604" checksum="6C53F25EB19CCB83" modified="2025-10-08" version="1">MSTKMLRSAFLQGPTSTIISQGMSVIRKVLATEQFRVSGLTTAEMYKLALKEAPPSNYEGHILEDRVVTKIPNTKSGRKKIPPPEPPHLEHPIRSMRYLKTQILPILQGHKEIRKATGKRFHAVPEAKVDTGNAKTKTKAKGKGNSNPGIAGHSQSSASTPSAPIPYTVHLWMPTQKPKVIKDAVASTAMTVDLGAEVGVGADWDHLNKRRQRARGEKVKRDLGIASQIRKSERQERKRAVWEVLMLKEEQEKAWSSAAPKVTVDDVDANSKPLHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQB2</accession>
    <name>A0ABQ8VQB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="30333" checksum="CFD3621D49E8B4C7" modified="2025-10-08" version="1">MTEYDYSPEAQERYKAKLQSIGKWVHNTEKYELANPFVSSPAPRSARLPGSDTSYTRHSPHRSYTAPPRGSSSSSAHHSSSSQAQYQQTSQIYAQPQQYTKYPQTVYPYPVSTPVPARQYAPPQRSHTFAVPPPPPPPPLPPQRPFQPPRRSNTIGGYGYSPQMIYDPRVGASRAMYPVYQSQPPTPSKRWFGKLFSGFRSSSPSPGQSPLSPTGSRRSQSKSSYHAGYYEHDRDRDRERSSKHYSERRSKSHSRSTTKHHKSRSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQU6</accession>
    <name>A0ABQ8VQU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription initiation factor IIF subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_817601</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="303"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="707" mass="76734" checksum="B1B6F5DBD9C1C497" modified="2025-10-08" version="1">MAPKAKADISLLFHPKKNKKSTSVSSPRPPPPNYALNGSRPSSPVKAKPSPKPSPPKPNVDDDEADLQLPDGPYQEFRIMSSALNGWKYDVMKFDSRKSVDILHWQGPIKLNRKDLRREDPSMSGAGQAVRPMLGLDGQPVIGSDGKIVMVDSEGRPVTENGASGSGAGKGKGLTNGKKKFQKKTRQVFIVPDDVRNLRKEERYPWVIEDAPGLEVWTAQLDDLGKAETHAFFMPAANDVFKFVPSHRYYKFQKKLKHDMPTDTTSVESAYIKSLKRDPSTWLHQRNGKGPSAATAAMFKAEADGQPPASGSLVHQTQQSLGPGGRRLKAVDSGADDLFGEDDEDNGAAKRRAKEFGGEGDMDEMVYEEDFADDEEKMDVEDTNDQEAKELEERLKKEYKNANKTREGYIDESDEEEEKPGMTKQAKRMQKMLRAREGNDVYESEEEEDNPYASSEEEDEEEEEIVPQTGPAVQPQSKSPTPSQTSNLNPESVKATTQINGTVPTTASRATSPVPGLGGHSVVAKRATSPKVPKIKPNLANPGRSGSPLASRASSPVSPVGAGGITTATSPTPGSRAGSPTAVNGVQNGQSQNKKRKAEEAGSSSPTLLSSSGPPKPKKRKAHLTTTVAIPAGPLEERLLIEWLKNTPTANASTRECIQYFTPYLTDEEKKAQFTGLVKEIAQLKNGVLVLRPAYRDSPAATPTASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQX1</accession>
    <name>A0ABQ8VQX1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14931" checksum="DF9DE517ADFF3E66" modified="2025-10-08" version="1">MSHVGGAEESRGTTPRGEEIEKQQDDARKKNDAQDMERRRQGSSIWGTLYIMATEQDQSPTRAEIVGVKRKRSESSVNSTVQDIELDNKVAGKDNITNTAQRLTVIESKMGRVVDQQREILNHLQKVEEGPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQZ8</accession>
    <name>A0ABQ8VQZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_816460</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="210"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="210"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="598" mass="68811" checksum="23DC9A88C97981E0" modified="2025-10-08" version="1">MRFTAPRSPSSSPERKPNPRRKRTSSSQRRRTSTFGLNSSSESDVDEVVDLESDSGESVPESSDSDSFCYGSESEIPPLPSKQKKLSSRPSREQNQIDDTIAAIRLRTRHHDPYEEWEKDMKKDSLRAARKNYNDSEAHFIHYQNQRRIEDSKRLAAAFKQDEMQLIQNLDGLRLQQQAREKTLQEKLAERNEILWKRIEASIKLEQDKEQVKLDEQRRVRDEAEKRRREEEENTRREEQRKRDAEERKRREEEGEKRKKEEEERRLREEKEAAIQEAKEREERLKSEEENRKAAGMTTSEEDWKEARKNLQVVKTQGTRLVKATPTLKPTWSSARRAITAKIGQLTNDAETINRVSSQLVEILLPINRPLPPPVYTALLSALAKALVLQAETEITAEKRSAIPLAEVTFNCLERLEGFSEVLFAKITQRIGPWALPCPIPEKDFDDRPWKDNQEVRRIQGFRSGEDGVLETQSQYTDRVKGVMRLYLSVLKITPKKTPLKKMFQLPRYWTWMARLLGSKTLLATAVGAEVLFVALEVLGADALQIWGYQFVKMLRVIYDASTEGLGGGKVLGGTTPDGIAARARVKLEVESIMKGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR79</accession>
    <name>A0ABQ8VR79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_755772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="1">
        <location>
            <begin position="50"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="151" mass="17242" checksum="CFF720EDC021C3AA" modified="2025-10-08" version="1">MFQVSHPAEIHHHLSLTSLSTQSATSNVDRNKSTNIQPFPSTVHRVIEVQYQTSTDPTGYISVFQYPLNGHVMMMNKYDGYVLWSALWKGMRKLVDAIETFKMYPLIMQAIRNIKDGSSAIQGTWLPYDVARNLALRIGWNIKEDLIPLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRW2</accession>
    <name>A0ABQ8VRW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translationally-controlled tumor protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_916193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TCTP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.10">
        <property type="entry name" value="Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011323">
        <property type="entry name" value="Mss4/transl-control_tumour"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034737">
        <property type="entry name" value="TCTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018103">
        <property type="entry name" value="Translation_control_tumour_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018105">
        <property type="entry name" value="Translational_control_tumour_p"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991">
        <property type="entry name" value="TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991:SF0">
        <property type="entry name" value="TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00838">
        <property type="entry name" value="TCTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01653">
        <property type="entry name" value="TCTPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01003">
        <property type="entry name" value="TCTP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51797">
        <property type="entry name" value="TCTP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TCTP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="168" mass="18751" checksum="1BD60622CB38F98B" modified="2025-10-08" version="1">MLLYSDVVSGDEMFSDAFPLKTVGDIVYEVDCSLITVKAGADVDIGANPSSEDADEALEDGATQVNNVVYSFRLQSTSFDKKSYLAYLKGYMKKIKAHLQEANPDRVEPFEKDAAAFAKKVVTNFKDYEFYTGEGMDPDGMVALLNYREDGVTPYFTFWKDGLKEVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRX1</accession>
    <name>A0ABQ8VRX1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ARM repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_815854</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055455">
        <property type="entry name" value="HEAT_PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021843">
        <property type="entry name" value="PSME4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23096">
        <property type="entry name" value="HEAT_PSME4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11919">
        <property type="entry name" value="PSME4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="11">
        <location>
            <begin position="372"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4-like HEAT repeat-like" evidence="12">
        <location>
            <begin position="1337"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4 C-terminal" evidence="10">
        <location>
            <begin position="1827"/>
            <end position="1912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4499051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1912" mass="216904" checksum="2E9660524C41A3EF" modified="2025-10-08" version="1">MEDDDMSFADTPAEDVNDQYSLETQIQSLQNYLKSVPYECEPPEYMQDRLGEIVGKIVVCAKAQNWHVMTVWDKMLQCWMIMRYPMQKSTRAKLVRLYYELCILPGIEARVVRSWADMLSRLLASKAGKRKLEATDLQLPWKPLWVALQKELWAMKRIQDTSRNILNILLFVAEQCKRYYPGSEVHEMLSTFLPLLTQETILTMVPVITSFLPLTHSNQYLPLIFKLWEAFNSGILDERFLEFAGELSEEYVAGPADDDDAEGGAAWKDIGIWTESQWDVLVSKGLGSMNVPVGITRGSSTTASHADAMANSQSLRIKKTISRQSAFAKILVYSISTDGPVKEPNLDETQSRDANPVQTPGYLAGSKALDTLDRLITSTESFFHPSNSGQWSITLTTFLQRLAAEFASRAQEEQRETCKTPVTRRLTSSMRKRFVKTLRTPALLAMFSKDPMSMGLAQSALRILAMLEPSLIMPDLLERSYSGLEVVNETHRTTAALSMLAGIARPLTTESIWLPGQKHVVPLLELCIPGIDVNDPAKTVFATMFIVAAVQHIKLGDLSIHQSGIPLTDDAGPMEIDDDDTQLPAGVETGMPALSRSEERALTRDSTAGFADWVVALFRRVLALYENLPEEGGRKNTTGGKSEEGVLKSIKNMMDVVCLHLSDQLFDLVLNLVFDYATTNAKSNAVRAFGQLVACLARVKPEKTLSKFMPYCSMQIEEELKHGASSTRTTSTHSVIPSDTTLHWNMAILRGCLGYGGPELLKHKSNIISLIQLLVDKTKNERGYTGTGHLITRVLHTLAGVYPHDSRFVNASEWNDAEFDQDHNLQWGKFYKPQDVEIEWHVPSGPEIDFVLQILDEVATPTLTRIEQLLVRVPSWDNADRNDFCRYVQVVKSIWAGLPTFLKEKNKIVQDHHLYDDTETLDLLITHFDVEAGFTLSDPNDPRYQKVLSCRTQFGKVILSAARALRQRREGEDHIDAVIGVSKAIDVYLLDYGISKSHFDSLQKSYSTARDMNRLWPKQVENSRLVYVKRAQVYHSGRVYMHSLYRSRSALDDELIGELVESSLSPYTRVRRHAQGVLLNVYGIYVRSTRSTLAVLLKALTKGNDPDRMKGALYILGDKGIMSYALADEGFHTQYLVSLLECQHEEKPSIQKLVNSFAYECLMHLHEEVLHTDAYALQTPTIDQALSHLSQEFPSTFIPERQLADALSKAPNRVSKRNSIYEKTISSILEIGLRPNTHWRYEQITARMLYSLIRRDIPLPPSVVEFFLKHSISPQPSIRRNSQRAITKLLAHMKYRAYSKSGHELWTEEWTNPLQVMVTISDPAMFLESLQRPSTPETIYVDKIRTGFVNWSTQITGYRQTDSESSVMPWDVDAIPFLQVIKTTITTSDYYSKLLLLWGQESAKTNSTVELRSENVLYIKSLAKTFETDGLAKLLEVIDPLLFDSDKFKQRAGGEVLTGLFRGSKHWSKNNANQLWQWTMSRLDRIFAQIKPDTLNFWESIFTYILEERDPRRNAPLVDWILGLSLEFNGDSAFDMSKSLTLFTILVDNMGILFNPMADKYVTLLLDNVNTSYAEIRGQLAHLLYTLIKTQWQPYYPSIALLLEACQTSNDPLRIREARYQEKISKVVAQLPKWREERLPPPRVSLSEYDKVGLTLLQWIWVSAYGSQACLMFNYAVPMMPEILRMCDISDNNDLQVYSTAILYVVSAVSPRKEHIDIILEHFVTAIKSSTSWRIRHHALPALIVFFYRNLLYIPSEGVSKVMDVLLDCLADENVEVREMASKVLSGVVRVSQRQSILPLKKRFVSLMRKTRLPAKSDPTYADSLRTLHSAILGLCALIESFPYSVEPWMPPLTELLAPHATDPPPISTTIRKCASEFKKTHQDTWHKDQIAFDEDQLQSLSTMLVGTSYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSL8</accession>
    <name>A0ABQ8VSL8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proteasome maturation factor UMP1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_789159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the POMP/UMP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008012">
        <property type="entry name" value="Ump1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828:SF3">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="139" mass="15641" checksum="2E6268DECE4A5A8C" modified="2025-10-08" version="1">MDPSLRIVPASVPKTASVVETSNSLGLHDTLQYGPRTIATEMKTEGSLKDRLYNWEETQDNLKLTMMRNTYGLHAPMRLLMERRIASANPHMTLLPQTNLQLDILMGRDESVEAADVFAGPLSGPPLDIRQDMEKKHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSN6</accession>
    <name>A0ABQ8VSN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone deacetylase complex subunit SAP30 Sin3 binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_876728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24186" checksum="6D447E24CF37103A" modified="2025-10-08" version="1">MSGTAQSASSRSRNQNRKKVNEDASYIGPAAPTTAGVKRQAADRAEGDSSRAKRKKVEPIHVVQSKLSDSENKISLVDFAKMPSPFVHRYLSTFDLIPVIRPLPNTVDEPPPPYSLSLNLQQPSRAPSPIPVTTPANRPRRDLHPKDQSRRRSSRLSDEDNFFQRTPILADVHDLHLVLAGMAEKHFREMAPINGREEVDTLAAFMFAIDKATGGRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSW5</accession>
    <name>A0ABQ8VSW5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lccl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_23582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="22373" checksum="71D4F657F221243D" modified="2025-10-08" version="1">MAVPAEFTTLDISGKFVMNKSLSDSTEEILRLQGIGWFKRKIIANGTLYLSIRHYKGDDGSEHIDIDQTLSPGGMGSREERILDWSERSKEDSLFGAVIGRSRRLAVEEIDDDYLKTGWDSTEHGLIQSYVSSDTPKSGTSWIANQIWGVEEIDGVRRYLRHVFFTGPQGEEIRGRLVYDYMEQRRHRSLCIYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTU4</accession>
    <name>A0ABQ8VTU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="11">ARD'</shortName>
            <shortName evidence="11">Fe-ARD</shortName>
            <ecNumber evidence="11">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="11">ARD</shortName>
            <shortName evidence="11">Ni-ARD</shortName>
            <ecNumber evidence="11">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADI1</name>
        <name evidence="13" type="ORF">C8R41DRAFT_813750</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="11">Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="11"/>
    <dbReference type="EC" id="1.13.11.53" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03154">
        <property type="entry name" value="Salvage_MtnD_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027496">
        <property type="entry name" value="ARD_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418:SF0">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11 13" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="3 11" id="KW-0533">Nickel</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4499806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="21111" checksum="FE7BAA176F12656D" modified="2025-10-08" version="1">MHAYYFDNQPGDQRLPHHNLEPSSSVDVETLKRIKVESWNIPVEKGYEEKLDDIAKERAYKNRDVITLSKENLGEDFEEKIKVFYKEHIHEDEEIRYILSGGGFFDVRQASTDAWIRLAVSPGDLLVIPAGIYHRFTVNEGNMAQAVRLFKDEPKWMAIYRGEESDANPHRIEYLKSIAVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU63</accession>
    <name>A0ABQ8VU63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="787" mass="91005" checksum="CF14149E0F24B60D" modified="2025-10-08" version="1">MSYISLPYPVLPSVPSIIAEDINSSHKEHLKLHAIYGTEGRKTRQSSEVISARIIEEWRDPWVERWMEDQVKCETILNWLHDAILIDFEQPLVEALNLFLSVQVLVSYGEIEQALQELSSWQRQIGLNLFNHQKNLALDLINQYEDELQDPEDSDLDSDNDSDEDYNDDDYSDDDSNDDSDDDSDDDYDDDKHHHQRQKIQNRRQRDPSPDKTSYLPLCKEWNSKLRNHLLMADGDGRSAKDLEIGHREVARAIQAMKKHTYNFQTSGLARTILELTNRSAYYDKPHQASYARRFGFGLVLGDVLGRWTPDEWAQQAEESLKENPPAGYNKSGRDLIEAITSHPNLIPNVSNPAAIFFLCSSDNFQFAWRRWLSWGLDAAGYRVWDCNSEALYRRTMQYLQVQRLNQRQWDRAKREWNEIIFFIIERSMELRNLLKDVDKQTHQPNILHCTKCASEVPEKRCVQRIDVELNTDPDFVERWEGVGVTKVPPEERMKPRKGRKASEAAEIVDPDEIGLRKIAIRDEEVIQRCGKHIFLLFSKQKLQDFIWYNAFSHGPNGTFDRLVRYSQTPLGVQPVLRGGKFDFWVVGQMIPFGARQPSGGHLADHYTFYQGINADTLWGITVLFEQAEMSATILATARAVHPDLVKKIKNQSALCERVGLCGLNLFNCSGYTAPQHYDKDATPSLCAQFVLQAEKKWSEFAFCALQYGYYFESHENTLWSFDSTLLHGTMLPSENTILRLRGGANSVGTHTTTRERDRRRAERNERTINNYHLRQRAWAGHENVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUQ0</accession>
    <name>A0ABQ8VUQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_811743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046969939" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10495" checksum="D3E6984642AA661F" modified="2025-10-08" version="1">MDHTESKRTSVSTLILSLLLIISLNVMGLMAPAPSGQVDIAFVILRRISNFSLTPHVHNSARLPFTVRSQCILLFFHLGKDNRNESIGDHQRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUU0</accession>
    <name>A0ABQ8VUU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_710233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="256" mass="28294" checksum="36FE61E172A423D6" modified="2025-10-08" version="1" fragment="single">KKQVKSSISKELQHHLWELPTCAHETHAPPVLSLCIGLPIIIRHNIATELSITKGQRGTVYAWHESTGAFGQCILDVLFVLLDNPPTPIHVPGLPPNVVPLTRCKTKGIVALKNDVKISVTRNQVDILPGFSMTAYASQGQGLNPNATDLNTLNDHHAIYTALSRSRTAASTVILQGFDSRLITGGASGPLRKEYRELEINLLIESFLAWKGTTYVPSQVHSAVSWSDKDPYVQQLEKPLSWSKIHKKAMQKLMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW99</accession>
    <name>A0ABQ8VW99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_863217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="155" mass="17321" checksum="31983F3333949C9D" modified="2025-10-08" version="1">MIRGFCHLAIGQETVSVGLVHGINKNDKVPLGASIAFAQKYTKRRPVLLLYMVTALLTRIKFLKLSISSLGMSSRYRCGQDSEISLASLFAKMECWTLVLSTVLARKFRGCEVCKTFMASNVIFRSGNLLDLKQIDKDAIEEVTDNLLNTQLCRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWI1</accession>
    <name>A0ABQ8VWI1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_753162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045912">
        <property type="entry name" value="FOXJ2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46078:SF2">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46078">
        <property type="entry name" value="FORKHEAD BOX PROTEIN J2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="7">
        <location>
            <begin position="38"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="5">
        <location>
            <begin position="38"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="295" mass="33260" checksum="7A252FFB361D9ED7" modified="2025-10-08" version="1">MADPNGDIVNGSYYPENDLTGGLPINLDSLRDGPPGSKPFYPYSTLIRYAIKGSPNQKLLLEDIYYAIESRFPYFRTAPNGWKNSVRHNLSLNPCFEKVPRPLTDRGKGSYWTVNDNVDPRTGVHRVRKKKGPKGKGRSSEEPDVDYHPSESFEPSPQYIPAPIPADTADPNRPQFTPYPPPPFDPHFPMMSMRFPVVGAMPMSPDESFDVDENGNVDWRLAWLKEIGHLQQVTAEQEKAGADPEWYRMMLVRVRTALMPPMMNPEAMHMAPMVPPNGTVDPSQQSAQPQQQQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX28</accession>
    <name>A0ABQ8VX28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_750676</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF81">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="19"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="517"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="543" mass="59108" checksum="6533EAAC6AD0F4E1" modified="2025-10-08" version="1">MTFRSEVRELVHYRNAYLLALSAAMGSIFYGWDIGLIGGIIAMSSFQSSFGVNKLSTSAKADFNGNIVSILQGGCFFGALSMGYFSGKFGRKPCLIASGVIYIIGSTIQSIAGLGSSAATGLSVLYFSRFLGGIGVGMVSALVPSYVSECTPRKIRGRCTGMIQFANNVGIMLSFWVNYSAVLNLAPTDMQWRIPFIVQIVPGALFIIGMLFQPESPRWLVEKGRYAQAAQTLAYVARVTPEDPAVLVTLDEIKEEFEGRDKLTLWQQFKGMGASRATAIRCFIPSLVMFFQQWTGTNAINYFSPEIFTGLGITGTSSTLFATGIYGVVKVISVGLVLMFAVESFGRKRCLIVGGIGQGLMMLWIAGYSAIHPSGGVVPASYVSLVAVYLYAVFYCVGWGPVPWVISAEVAPNHLRTVSLSVAIGINWLFSFTISKITPIMLNNITYGTFLIFGLMCIIMAGWAYVFFPETAGFALEDIHFLFENDVIVRALQDAPLGRLFIGKKRALPVEELRKRETEIDQRSIKEDDAKASDDGVANVAPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXK9</accession>
    <name>A0ABQ8VXK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_286311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="567" mass="61982" checksum="76951085BF2C11C3" modified="2025-10-08" version="1">MADTAPRHKAQGVAVMLLVDNSRFTEIAWSDLRDLYLPSLFDKLSSVHASASITTFVQECCSNGTMDEVSPLTPRKYHKFQDAIRDLRFNPVTTYRFTGQLILETIKFLSATAALARHIVILGSSPLQNENSSIDWHRLAQSLATGSIYCHLMLHTHAAGPTDPLSLMFDETLRLQRSIEDNAWFTDHKSQIVLRLTSVHTQTPRLEVTPFKVISPLTPSRQGLLPAPLTHHLPSASNQSMHLSTSPTPASDEELPSIVTQLQQMHGLTKKKVYGTKPKRLPFVSSEFYRESSRKAASLSPVSPSDTNHGGRVTSPSLIDRTTRVHQNGSVLPHPGIARSSADVGSSGSTSVSHSAPSYRLPTMTMSVPSSPVSTRPPFYLDPPEVSPRTTYHQPQSLSIMTASQPHAVLNSASYFTEDKTVKEYSRGDGGASLSTQVDRLSQKIQNQNSSINATTSYSVPRSVYRDELLSHLGGPSVGSTSSDHLFTQDPSSKSTPYAENAQKIESYPLLSQHTPWHAPYDSQYDLPSNQISTISQYGMTPGHSTASSYPSSPVSSQSNSLTGWAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXN1</accession>
    <name>A0ABQ8VXN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_808049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="97" mass="10865" checksum="D361765B5AE14C93" modified="2025-10-08" version="1">MTQEPADVKPKLNLQIQYEGNQVTVKVKADMQFKKIFKAAAIKFNKEEGTLKFTYDGNRIQEDDSPAGLGMEDGDLIDAFLEQLGGCRCITPHSETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY69</accession>
    <name>A0ABQ8VY69_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_914073</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="39"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="409" mass="46273" checksum="168BC81DFF3805AE" modified="2025-10-08" version="1">MSERRFIPSQLDEVEDAEDYRPGGFHPMYIGDEFANGRYGIVHKLGFGGSSTVWLARDRQQGSGKLVTLKALRADASNADSPDLVIPKLLQRTGLPDAYLRTIEDHFVVDGPNGSHDFLVSAFSGPSIQAMLYRPDGPRLRAALARKIAAQAACAMEHIHRAGFVHGDFTTSNLLFRLNDKVMKWSDNKVYTHFGSPIMDEVRTCSGQVVGPHAPSELVEAIGHDAFANILEENIIVIDFGQSYRAPDPPKDYEPATLADYMSPETRFEKRVGPEADVWQLGCAIFEIRTGGPLFDPFFPSDTYIIPQMIETLGRLPDPWYNAFRNRVQCFEEDEQPEEGSSIREKLRSFGTPKRIPGYNRGPMFEKMETKMDDKEAELLTDLLEKMLRYRPEDRIGIREVVDHPWFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYE1</accession>
    <name>A0ABQ8VYE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_203672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="3">
        <location>
            <begin position="42"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="142" mass="14895" checksum="8C6558EA29B02BDF" modified="2025-10-08" version="1">MSVIGVSSQATSGNPANAASSSQSNGVPSSTSSASVGVTPELEQTLALLSSHRSVLGYMLLSRGHPASIIRHSGGVFDGEHGKKYAGVIARIVETVQAGLEEINGVESEGDDVKFLRVRTKRHELMISPDGRYLLAVLHEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ28</accession>
    <name>A0ABQ8VZ28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rho GTPase activation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_753552</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="1095"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1712"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="6">
        <location>
            <begin position="1822"/>
            <end position="2016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="47"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="648"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1011"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1268"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1640"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2022"/>
            <end position="2077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="655"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1013"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1273"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1647"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2022"/>
            <end position="2049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2052"/>
            <end position="2077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2077" mass="230239" checksum="E2D83AD2EF7417FE" modified="2025-10-08" version="1">MDLTSRNPNSLDLSSIGFNSSQPSSPSSPLRSTYGLGDLRAISRRAWSKSADDLSKLSADVSPAMEEKIAQYRNRSNSNTSPLSPGGPPSAPPFFERSCSHGTGVQPFPSLPRINTPSSATPTVSISISAPAIDEATHKPAPSPTHVHTRSYSFTPKLASKLSAPRFMPPSPKRKGSAGSEMEGTSAPPVPTRGAFPFSSSNRTLLPDSSSSSSTSQPVHRSTALLAPPNIVEPFNESSESSSPKRASQIVYHSGFINKFADGTASPHQLGTAKAWKPFKLELKGSKLYFYKPPSDRAAAVKELFPTELVPVNQQDEDEVNNNGGVEGEVEDDPFASATTTNTRMDMRSTRQEGSIVQRKKRAFWGRRTHPDLSKDAEGIIEKGTFEALTHEAVFGTTFFGLVEGEVTAAEISSGIGKAKVGSMEQWKDFAASILLCMPHLVDQTKFETELMRCCEFLVSGAEEEKKSVEKQRVVWLVAEYLRYHGRPLEFPDWPEWKSEIAPEAIMVPPPTMPLPRSTSTQALYNPTPVASPNIGMFSPRPGESSDMSLVNALIENGREATATPQSGSGNSYFDLTTPGALSLSTPIGTPSSPTANRTPWASALDREGLSRDVLLLIDPNTIARSLTVFHLSALQELPENLTADFVLGPEGSESHPSSTQQPLSLSSATSLFGSDDHPHWLTKLLLVQILGADTSTGYATLRGAQLSSPSRRSEDRGPTSRTHSRSEVISTWIKIGELCRLNGDECSWRAILHAICAAPVARLEKAWKRVNPVAIATVESWVQPVKDGDPVNGIREPRITPWGGNMRSIIREHLSQASVPGSTGDVLMLATLDRVRMLFEGFRTSVSLCPRKTTILEERSNEEVQKLVSYWKDIVADGGASSGLGIKFHRVEQFISLSLAAEPRRKGLYEPFYWAKSNGQPSSTAPLLPLLFPEPLPTITLLDRSQFFRGRVDSDSNDFQHLRAVDGHLRPEGRASVPANDSAFGILNQGGMTIPVHDGDLLLVVQNPITDSSSTGSRPSSLVRSRPPSSDIDPSSLLDGKSDKPIGRTPSIRVKPGSSANLERKSSVARRSSLPSLSQRQPLTLAENSSEPPLRVLVQAGTLDRLVDILVHGLHNVSVSVADDNGEMSLRVGMTRELLLDHKEFTRVWWNVFRSFVTPLIFFELLRKIYIKSQPAGSPPLPDQYLAAISSKSQVLDAMKLWLTKGGGAQDVLDDSQLLQALRAFFASSSDHIIHSSAATFENPSVRQAWDNMTESRQALEQLLRSQTMRPSTSRTQTVSRNTVTTTESRVRNLSTREPPDMDRMSPEEFVDNIDGMAFAAFNNVTEEDLYITSDLLEVQSTDRTGWFPPREASSLDEYIEIQTIHSHIQDVEPSYLISELSPESLYRLLPPGIRSCIRAHSIIRKWLISKIVAPRIGLRARQMRIEFLLQVIEVARLRNAESSSPNSVYEQPCVRSFVEAAVTSAILSPECRMHHRAWQNVSASRGCNYDTLSQLLARPKTQSVASRDPLTVDMGWLIERILDVIAMPDLVESHNEEGQNLVNFDKRRSVCNLCNFISNAPSLLSRRLAHQNDINRRGFERLNNIEREIFSIQFDIRGIKDEAYREGAAANAPGTPSKKISRPFQRLVAIQMDKHRRDKNLRVRLQKEKTQEQFRNEKREEQLDKAMKGGRRPTSVAQKQHRNKKSMSSLFSFMRPISSAFGVDNSHSPVLRRTASELDFTPSGKPTLVLNLTDSSVNQFINNERSFTFRLDTEDGGHYLLQALSKRDMTKWIDTLARVSKIAAKRRLTYIGNSPKPQIADHIHEQPVTATRDPKAVFGVELNFLLEREYGGGPVPPGTIPFVIERCLAQVEARGMTEVGIYRMAGASSEIAHLKEAFNRGEDPLDVYTDIHAICDLIKSWFRVLPEPLFPPASYHEAIDIIKLDNLDERLTNIRRIVRNLPRAHFDLLKLISEHLDRVTDFEEHNQMTAEALSIVFSPNLLRAPQNDFLLVLSNMPYTHKLVKTLITHFHVIFDDADAEADPEDDLDTPIAEADEDDDDDEEEEEERTFTSYLSPTLTSQEEPSSDPTNHSKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ77</accession>
    <name>A0ABQ8VZ77_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_5775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="67" mass="7866" checksum="8A4E6AC8B50B076D" modified="2025-10-08" version="1">MGGPNLEVFKFSLNTVLPYKEQLFPPEQRLLQQLPTDQSSLREELARIKGERLARRLAKQEESDRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZJ4</accession>
    <name>A0ABQ8VZJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046771700" evidence="1">
        <location>
            <begin position="22"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="129" mass="14000" checksum="FC16CDAA8B1B29DE" modified="2025-10-08" version="1">MRFFSVLYTIVAAASVAFVSAQEAARFGIVNVTPTGLLTANENITIMYNSTLAQNQPLYVDFYLEGEFSNGNAAPNLLISRNNYTANQTILLQNATVPNLDLLGNVTYALWAWVTYNQSGLLQIGGISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZM9</accession>
    <name>A0ABQ8VZM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_786135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="8">
        <location>
            <begin position="19"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="353" mass="37577" checksum="B795CCD3BA502AAD" modified="2025-10-08" version="1" fragment="single">MANFVIPKFQTAAVVDHSGADIRIDHEFPVKSQEELLPGECLVKLDCSGACHTDLHAALGDWPIPAKTPLIGGHEGVGIIVAIGNNTAHSPVKLGDRVGIKWLADSCLNCEDCRKGREQNCKEAKLSGFTVDGTFQEYVVSFVNHVTPIPDNIPSDEAASVLCAGVTVYRAIKYSQTSPGDWIVLPGAGGGLGHLAVQYARVRGLRVIAVDTGDAKKELCLKLGAEKWIDFMECKDIVAEITSITNGGAHSAVVTSANGAGYRQAVDYLRPGGTLMAVGLPGKATLEASIWFTVFKSISILGSYVGNRQDAVEAINIAARGQVKVHFTTKPLKELENVYEGMKAGKIAGRIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZQ0</accession>
    <name>A0ABQ8VZQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="6">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_806129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="334" mass="39313" checksum="A29CEF9D053F2C95" modified="2025-10-08" version="1">MHGVRRARQTQEALEAKRLKDQSKLHDYLALSDDVLARKKQKDWSREALRSTTQLLQINPEFYTVWNYRRHILVNGIFPESTPEQIKDLLKDDLSLTMAALKIHPKVYWIWTHRGWCLNNVPSGPGVDGEGDLRGWEKELWNQELFVVEKLLDADPRNFHAWSYRRVVLDSLPVPKPETSELAYTTRKIESNFSNFSAWHQRSKVLSSLWSTGRLDQTKSKEEEFDLVQNAMYTDPRDQSVWIYHRWLIGSGDNKEILDREIAVIQSLLEEETDSKWCMESLVHYKRLLLHNHAALVDKSALTRNCIHLLEQLREVDPGRRARYDEIELEITRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0B9</accession>
    <name>A0ABQ8W0B9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_913295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="93" mass="10076" checksum="D58CCDA746BE7044" modified="2025-10-08" version="1">MAVGVSSNTSQGRLGEPLSLDSTFTKFQAEVARESVNNMIKKNTLRVSSFAEEDSLESLLAPDSQGCLQFGDPKKSNKRTTRALFAILRQPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0M7</accession>
    <name>A0ABQ8W0M7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_190581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="315" mass="35257" checksum="55C989C3D38A1597" modified="2025-10-08" version="1">MSFPVPKKTPIEARTEKVLDVRTERIKDPETIYLGCSLSSQPSCHWQRNGRENVLVFTPKPVDNDETAMAEKCTEAVLSMVCRLRSDGFWLACDGGFSPASTIYQEFTDVELTAVGVIPDTATNPEAETFVMDWPIAQGNLRSLQDLVAVQGVSNKGFFVSAPNSTESIGYRFKHRLFEELDPSVEVADEDDRKILTDWPRKNDAVATALDKLLAQNPLKYRLYPLQAYDYHCEPIDALWYRKYLENAVVEVRFTLSHWPISGKSNGGGANVFRANIVDILVLCTPPPVVVSPRKRKVSSHHPASPTKKRVLSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AV62</accession>
    <name>A0A9W9AV62_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8J55DRAFT_469367</name>
        <name evidence="6" type="ORF">C8R41DRAFT_860544</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000006">
        <property type="protein sequence ID" value="KAJ4491317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AV62"/>
    <dbReference type="OrthoDB" id="10249311at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="31"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4464065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="145" mass="15848" checksum="206D9CF8483ABC89" modified="2023-11-08" version="1">MSDAGDDIPVEETAVEVTTEAPKGKLSIEEALQQVLKNALVHDGLARGLRECAKALDKRQAHLCVLVESCTEAEYIKLIEALCAEHTIPLIKVQEAKVLGTWAGLCKIDREGNPRKVVGCSCVVVKEYGVESEGLNVILDYFKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWA6</accession>
    <name>A0ABQ8UWA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000154">
        <property type="protein sequence ID" value="KAJ4463717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046303609" evidence="1">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="148" mass="16277" checksum="B36EB3B848947CA9" modified="2025-10-08" version="1">MHFNPTFVFVALLSIAHAAPLNGPKNTDLINEALQVQPGRLVNVILQGNDEVHTGSSAEYEKDAEKILEAWYKRAKMEIPEGGFHIVTSGNSGRNRDGTLEFSVWGPAVSEKCRYEHSGCLFKYTPKTQSVSITGGPERSLLSRFSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXV7</accession>
    <name>A0ABQ8UXV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_985244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="194" mass="22065" checksum="3CCD692B45667B74" modified="2025-10-08" version="1">MAGHIRMVLLSCLSVNYLERPNYFLDQGEDFKEELQLTITMLSWLLTLPASGVVSIVTTTPGCISLIARLYLLAVRMSLTTEESLLFARRALQNILELPQSAWDPEFTKELNKTHPSAVNDILHRVIKDTERRPMNCPPLKDGSIILSNICRAPVLNRILIRKDAVYWICRAIHKLVVNQTMVGKENIKIAREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY13</accession>
    <name>A0ABQ8UY13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_858415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4465474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="434" mass="46971" checksum="6FB2914D531F4ADA" modified="2025-10-08" version="1">MATTFIRTYLSLHRVEAPRLTLFGRSLLLLTSEILANALCWTAAGVMFGRTKETKSILGLAMLAWTLGLRHALDADHISAIDNATRGFIAMDQLPVTCGLYFSLGHSTIVIVVNVAIAISSNIASKLDGVGQVGSIIGSAISGSFLFIVALMNSIILFKLMRRRRLRSQAANSDSADNVPYNPKENHMLMMRIIGPVVTFVNKPWKMYPVGILFGLGFDTTSSIALLAVSALTKTSGGKAIPPSDVVILPFLFTAGMTLVDSLDSILMLYSYAGFPEHSLRIFERGRLDRDSISDLRVTHPDGDQIESKVDIQVPVGTEAQSGAEIQITRNAQVKQNAISGLSILLTLMSIMVALSISLIEIMALIGDNCTPCKIAAQAEDGGGLAGRWWRGWNVANNNIGYIGAGIVGAFVVLVGGWYAFTWVIKRIRQRRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY20</accession>
    <name>A0ABQ8UY20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_111422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="165" mass="16834" checksum="A945EE64430996BD" modified="2025-10-08" version="1">MGRGGGFNNDVIAGGAAGMAGIGRRSSMNATALNRMKSQNSTGALSAPSSGSSHPAQPESYASHFTPGYAGPSQQDSMNRSTSAGSGLIPEANEPGFIAAGANFSPAVHDAAFGQQNQQTALPNPFTARLESDENADGGAEDPYGGYGSEEEEEQPRKVLKVANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYJ0</accession>
    <name>A0ABQ8UYJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_781090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052751">
        <property type="entry name" value="Plant_MAPKKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011:SF4">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="318" mass="36305" checksum="AD7CBD32FA5AEE08" modified="2025-10-08" version="1">MESGPERERRQETVLREATAVHLARLDRRTYPPKVHCRQLSEFAGEPLDQMTNWCIVLKAFESLIIALSYMHSAGFVHRDISAANVLVKDGNAKLNDLEYTKRVQPAIEPRSGSSDVKTGTPFFMPVEVMKGEYLFRPKKHVRKSKSAPSFPFRYHYIHDLESALWVFVYLLMTRWPISGPPPCEEQQKARDKGFSKIFIVERREEILDGGQTMVDLVSESMPELFDSAWDCALELAAVVKEKYCALQESLPIDFNNAFHPSLYSDWRRAFIRCATAGWTGVVTHSGRTKRAAEDDSEKETMKSKVIQLSDDLSVNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYY5</accession>
    <name>A0ABQ8UYY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aryl-alcohol oxidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_780621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000116">
        <property type="protein sequence ID" value="KAJ4466344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4466344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="613" mass="67122" checksum="7F8F05EF518BD593" modified="2025-10-08" version="1">MCSCTYAAFYTDPVKVQHKKYDFIVVGGELTQHHHTAGSVVAARLAEGGNMNVLVIEAGISDERPDTAILDVPFFALGLTGGVSYDWNYTTTLQQGFNNRSVPYPRGFILGGSSSNNGLIYLRGPSQDWDRIANISGDRGWSWEGIQPYVFKSEKHVPSWSHRDDRGEYDPAVHGYGPLHTSLTANVSDLEYHVLKAANELGDEFSYNLDLNSGNGLGLGWFQNTVGNGTRFSSSTAYLRPALSLYTNLDILIETRVVSLQPTPGDNRSLRDFRTVITSKTPNSLYLISLTSSYCQQIDVGPHILLTASKEVILCAGAIGTPQILMLSGIGPKEHLLENNIPVILEFPAVGRNLQDQPVIGFQWSVPYNTLSAFTSNQSAVNTALLQWQYDHTGILASSCAFNNVAFLRVPSKSVLFNHHRDPSAGSTSPHFQLVFYNGFLPNSGQGPPDKGNWISTGIVLQAPTSRGTVLLSSNSIFDAPLIDPAFLQTSWDIGVMVEGLKAMKHFFATSAWSELSTNPFHELPDLNSDEAFENYTRSFAFPIKHPVGTARISKIDDKNGVVGPDLKLKHVQGLRIVDASVLPFAPGGYPQAQVYIMAERASDLIKEDHNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZF4</accession>
    <name>A0ABQ8UZF4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="21487" checksum="AB3FB88A973F012F" modified="2025-10-08" version="1">MVNNPAREWVKNFQTRPLIPTSSDLLAIKSITNTIEPTAQNEQQRESVPKADINTVDANLIDMELRAIKARLFESLGQELNDKTKSQSLPGYHTRAQYLRRIVLHEPVLSLKAPNKVLFKDLNLDEEFTPEDVERIGVLLGKQMQLGLLWWKDSLIEAMSIIRNKLKGTAANVGEFKILGGWVFNTPHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZR8</accession>
    <name>A0ABQ8UZR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatase regulatory subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_855634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="440"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="611"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="735"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="801" mass="85349" checksum="775CB38CB51B75CD" modified="2025-10-08" version="1">MPYSVPTPPPSSLSVSPPPTHTRSLSSHPAPSYKFSNEIGPGAFTPLGSLPRRTTGPILIGNPRATSATAKRFHFKSSPEVSSSDSSDDDDDDDRGKESRSNLNQPRKANVGDNDHDDHDDDDRSYAIPPLKLRVNRLGSPSFNGVPFPRSSPLSSPVLGSPLPSPTRAPSGLLSPLGLNSPILETGSLLLSPNDSNISQLPISASNPIYSPYKYSPQDGTAFTLPLRPSPTRSTSSPHISNGRPLKSSLKSSSSASNIHPHVHAVVHHAHHIHSSHQRATSAPTTPAHDLVGDHSSSSSNSSVSNPSAPGSGTVSPTTPKTVHFPSLSTHLERVRIFHKSAKPASLLTVRAQGEETETETETDRGSDWGYAYRGNTARNSNGAFPFPKMANSPLSSNISIWPPSPAAGASEYRKGSIKLELDMTGYPIPDPFSIPPSPMTNILLESISLSASVPDDKLHLQGAFIVRNINYQKDVAVRFTVDDWSTVSEIKASWAANFPSPFLTQRSSSRDTDSWDRFTFCINLSDYTLASLPSKVIYFVGRYTVPGGEHWDNCGGRNWRVKFRLVKTDPDVQNPADLPAAFAAVLPPNAVVSSPTVSPPAISLTEATASSPTSLTNSISSAPSSASPVSIANPSSPARTEAIAQATAQRLRRFSLSNYVAPGAPTSSSAPSQTEEKEPNDILQRSSSMPDTRANISAGPQHLTQAAPRGHLSIVTTPPNVTPSSAVSPLNPKSASPPSTSPSSISTPPAEANSESLYNWFVQQWCFAGMPSSRLPDQNWKRDEHPPVIHNGNLGLEIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZU7</accession>
    <name>A0ABQ8UZU7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Postreplication repair E3 ubiquitin-protein ligase RAD18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_890340</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Protein modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000107">
        <property type="protein sequence ID" value="KAJ4467506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004580">
        <property type="entry name" value="Rad18_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00599">
        <property type="entry name" value="rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51908">
        <property type="entry name" value="ZF_UBZ4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="38"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="UBZ4-type" evidence="15">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="201"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="346"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="351"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4467506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="44797" checksum="6C30D670E69B8A11" modified="2025-10-08" version="1">MTSKTQIQRLMSDVQDPSDFPQQSEAPGLRLLDSALRCTICSELFDGPVTLKCGHCFCSLCIRQALAEKQECPACRESDVNEGHLRKNPAMEEAVTAWKECRPYILRILDENSRRVQVESSRPAKRRRLHDESGSTSEIICVESTASQDSSTPTHSEQAESDTPNSNKKDTQSARPDDLIDCPLCNKRVKFKDINRHLDKQCRDEPEPVRSSSKSQWDSILGSKSKVQSSNKRQKERVLPEDVDDSLPTKSYDTLRDKAIRDLLHEHDLLTTGDRKTIVARHQRWVIIYNANLDKTHKMRKSLTSLRRDLRDWETQQKNKTKHDLPDPTAYQIQQKSEFDMLVEAARPKETSSAIRQTLSRHGQTELSDSSRSRTKSLSPAETVIIVDCEGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZY5</accession>
    <name>A0ABQ8UZY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_779575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000107">
        <property type="protein sequence ID" value="KAJ4467518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="294" mass="33144" checksum="67E64ADAFC0F9320" modified="2025-10-08" version="1">METLESFWQTAEPILQSVFDSPEAPPKDLNYEAFSSVYTKCYDYTTSRKSQATAEGFPSFSSHQLATASEPGSPAALFLPPPSYKRIDEFFAERAKITYNNSPGPTTSFLDLARYVLVQFTRFSGAASITSRLLRYLERYVITQLIYEGHGWSTVGIQSDNISKKMTKKQLQERDQKLERWGYEKDADNNLGTLKEVESWAEAGSSLDRIVPIKSLAFRRLRVAFLEPLLADQGRLALAIGELLDPHECQEVEGSDKEELLLGLKDVFRSCGIAPDNLLRVKLELYYEAKDAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0B2</accession>
    <name>A0ABQ8V0B2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_984758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045592916" evidence="1">
        <location>
            <begin position="26"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="252" mass="28188" checksum="DE9FD15869EDD468" modified="2025-10-08" version="1">MLATSTISSFVLFSTILSLIANASAIPVDNTRIYGRNLTTLNSNGTQSILRRDASRTTTALTYVQHLQLVVKPKPKVDKDTVILGYMTYVKQRDADEYNKMKTLTTIPVVDTVYPLGQGAYLEPIMLMSPTDDFDKCVVLVRKQSLEKVSKLFVLNKHARPSFIPHLLKIYGMTQKAPLLFYQTPGYVKAVIPFEYLKKSPQDKEGTISSNENPLGIVTVCGPAVWDVEAPQMTWHNMGVTEWPLGLETVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0D9</accession>
    <name>A0ABQ8V0D9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_857280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000118">
        <property type="protein sequence ID" value="KAJ4466077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045318445" description="Secreted protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="8246" checksum="4ECA7F388EF729F4" modified="2025-10-08" version="1">MIVRATSQVLQARLFFGGVLLHLLLSVANIEGHSTTTQGPRQNFCTHIQGMVAGGMYSQLCLVCYMPVCKTWIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V131</accession>
    <name>A0ABQ8V131_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_898008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="45"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4468953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="308" mass="34030" checksum="279380A4D18C48C0" modified="2025-10-08" version="1">MDPDSFRKFATQVRKAGGNRPPQGFLAGGGLLVALVAGGLALNASLFNVDGGHRAIKYTRGERFHSRLRGVKNEIYPEGTHFAIPWLERPVVFDIRAKPRNIASLTGTKDLQMVNITCRVLSRPSIDDLPVIYRELGQDYDERVLPSIVNEVLKSVVAQFNASQLITQREHVSRLVREGLTKRALRFKLVLDDVSITHLTFSPEFTHAVEAKQIAQQNALRAAFLVDQAVQEKESIIVRADGEAKSAELIGESLRGNKGFLELRRLEAARDIATLLSTSGNKLMLDAQSLLLNVAGDNVNDLVKSKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V132</accession>
    <name>A0ABQ8V132_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_732377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="20210" checksum="48BDE179CDC9BF60" modified="2025-10-08" version="1" fragment="single">RPRQRGQRITSDWLLDLDDRECLWTFRFTASEIFHLCDALTIPMIIKTKSGYKFPHVEALCLLLAQMRDSGDAYCMTMLYNQCQSLISEIFNELVIYIDRTWSPLLTFNTNGVLAPECLTEYAEAVHEYGAPLTGIWGFIDCTIRHICRPSHFQRAAYNGYKKYHALKYQAVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1V9</accession>
    <name>A0ABQ8V1V9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_780194</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17480">
        <property type="entry name" value="MFS_SLC40A1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4466800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="491" mass="54324" checksum="BC24C888FE695678" modified="2025-10-08" version="1">MYSSLSSSSSAAQPRNEDEVPPGIPSAITKRLYISHFLSTWNSRVFEFGAILYLATIYPGTLMPMSIYALARAASAILFSSAIGRYIDTANRLHVVRLSIVLQRLVVSASCIIFWALISGRHWTRNLGPGSLAILAVFASIQKLCSIMNLVSVEKDWVVVIAGQNEVALRALNAQMRRIDLICKLAGPFVIAIIHGYSAQVAVLVNLSMNLASIIVEYYTIARVYTVVPALQEPKILPPNNESLADQRAIAHNFWSHFNGVWSTLHDFSGYFHHRAFRPSFAGALLYFTVLSFSGQMVTYLLSAGYNSVHIAVARTLSVAFELSATWIAPILMSKINPIRTGMWFVNWQAICLVAGVACFWTVQNQFVAASGLVAATILSRVGLWGFDLSVQVMVQREVEPEIRGSFSSVEAAWQNMFELCAFTSTIIFSKPEQFRWPVVMSLVAVSTAGVLYASFVRLRRGHLLHLPPCIERKTRPSRMGYETIGETSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1W8</accession>
    <name>A0ABQ8V1W8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 8 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_897892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04194">
        <property type="entry name" value="GT8_A4GalT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050748">
        <property type="entry name" value="Glycosyltrans_8_dom-fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13778">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13778:SF47">
        <property type="entry name" value="LIPOPOLYSACCHARIDE 1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4470036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="62636" checksum="D67E59FBFC853A2D" modified="2025-10-08" version="1">MSANLPAHPNHANQFQFTDTQDWFSHNIPHWRNLFPFITSPRPRILEIGSWEGRSAVFLLQNICGADIVCIDHFDLFRTSAGRERFRKINHNLSLTGKPFRVLPQFSVPALMNLLEKEILKEESLGNAGFDWIYIDGSHEADDTFLDGELAWRLARKDAIFIFDDYHWDKEPEDSKHHPKKGIDTFLDLHRGEYVKVTEPEHYQVVLRKTSEMRIGFLVDKEGLSADEGDAIKKVFGYGINVALVVDPAYATSAAVVILSAVENTTGRITIYIVDCGLSEEDKQRLLRLIDPLRANDVTMMFIALNAECLGKELGPVWAKLDLAEVLPIERVLYLDADTLIRTSIEMLWQTDLQGQTIAAAPDVGHPMGHDQMGVKMPYFNAGVMLVDLAKMRSRSAELKQLGRSMKDSKFRDQDVLNTFYASQWNRLSLKWNAQGLGTYARYPSPERDMLRLLDPMIDTPDPAIVHFTGPVNPSVEEVLSLYVQPPTAKPWGYLGAPGHPFQAEWWAIVERTGWEYTRSQSANMATAEMDKAISDAIRDFKERIFCVFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V218</accession>
    <name>A0ABQ8V218_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ClpP/crotonase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_777734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF75">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="30700" checksum="A71F5D4DEA83C22D" modified="2025-10-08" version="1">MTAYPLALPPGNPLITLTHPKNSLWIIELHNGQDSRLTHELINDGLKPALNAVEKEWRESWRIHMKDQKANKGEGKGALIIVGRRDQDKFFSNGLDFANSQKDPNFFQLTFDPLLERILTFPIPTIAAINGHCFAGGFMLSMACDYRVMTDGSSRRAWLSMNEVHFGAPWPISFAGIVRSKFGNDPMKRKMALEGHRFTPQEALEVGIVDYVVNGNTAAVLARAEQLGDQWSGNAQGGVWGSIKSELYRDVLETIHKDARPRNPLHEDAAAKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2K5</accession>
    <name>A0ABQ8V2K5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_870739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4470769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="251" mass="26792" checksum="DC589F43F561969B" modified="2025-10-08" version="1">MNSKPSTVASFTNYFRPHRGEAVVRLRSNAFGLISVFISTWLLPVPSVTSAMRMILSGSNTQNDFLVVNGSEWNFRKVVCVLELTIVAVLAYNVLEAFYALKYPRKPLAPSVLSPAKKSNPFGVVSPESAKKPFRILSPNSTPTSRSKIFSPSQSLALSQSRSSQYPPSPASSPSRVIRYSMPPKGSSTDGGVNASISSSTSTIPPTPSPSASLASVYRGKHASGFHGGRPMDGLFLSQMASGGDDDDDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3C3</accession>
    <name>A0ABQ8V3C3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_780182</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4466804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="504" mass="58302" checksum="A85E5235018C6507" modified="2025-10-08" version="1">MFHLRHLICVAGHEYEISHQTDAGQLEFEWVKRYGPTIRIFSCFHEEVLMIADPMGLQHIFQSQNYPKTRDIRLIAERVFGKGLLWATGEAHQRHRKALNPAFSTQNLKKFVPLFQETTLQLVKKWNARLEGNAAVVLNMAQWMPKITLDVIGRSAFDFNFGLLDGTADYNELYRTMRDILDSKSSSTLTLLYDAIRRRIPERFAFRMYTTKEDRRLSAFLSAAQRAARNILLRKQEAEMPNANSDDDKDILSVLIRATKHDDHRKKLHEDEIISHMATIILAGNETTSSTMSWMLYELSKHADSQTRVYKEITILRAQTGCHVSLTSAQYDSMPYFNAVIKETLRLHPILPILVREANEHDTIPLSILVKSKTGSLLPDVPIRKGQRILLHLGAYNRLTQVWGDDADSWNPVRFIDEKKEVVVGMYENLYLCSFHSTFQYSKRQIRVMELQVMLFELIESFEFSLPTEVLDIQRIPSILMVPMIRGKPELGVQLPLQVKQRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3L6</accession>
    <name>A0ABQ8V3L6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM Nup35-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_589352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="50498" checksum="9562AB48A283F46E" modified="2025-10-08" version="1">MDDQPYTTPDEDPFSVRPLLQPRRRRSSMLDKWIQEQQKLPSSPQSTPRASCNTLGPRGNPYLAYPGLGIPQESRSRSGSVITLGSYDLVDDEDIPQGSIPEIPLSPSTPTSTAHKGFLGTPTSFRSLHNPFRSQSPARSSTPTAETAPRTPSRKPFIPLNSRLGQGSERSKPKQHNRSSSLSILNNPPLSPSTSSHMPEPSPTPSKWRPSVLGYFSSSATSQVSFIPSETLYTPSRPSVSSNSTVTTTTSITSATATAKNNDAPVTTARLPLNSGVASFRLPRRSHADMLHVQSSNSVENNVPNSSYARPSKGGSTRIPLAPKSTVRIANSNVNPIHDDDEERSLAPVHVAKHNAKPEIVFVASSKTNTLSKMSFAALSSKNNKKKRLIISGIASNDVRKFEGVKNWCESFGEVSHIIRMPNNDLHVHFRSADVADTVCRLRARVYIVGCGSVGVSWTTGNTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V435</accession>
    <name>A0ABQ8V435_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_870522</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the type 2 lipid phosphate phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03388">
        <property type="entry name" value="PAP2_SPPase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF28">
        <property type="entry name" value="DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="10">
        <location>
            <begin position="107"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4471921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="605" mass="66731" checksum="4313F03CA0120046" modified="2025-10-08" version="1">MLGEQRDERDTQNNHDLDNLDDLDDFSDLSSSQYSPSEFSSSNSLSPTRFYLRSLLLPIVERESHVISRLQRRFRTPFWDKYFVYTSSLGTHTFFMILLPAMFFFGFRDMGMGLVMVMGGGVYASSIVKDLVCSPRPLAPPVTRLTIGNHHLEYGFPSTHSTNSVSIALFFWGYVHTLFYDDSVVYWTCTVILLIYTLSIVLGRIYTAMHSFIDCIFGVLLGASVWWCVTDLNIGGYLTGFGFSARLQAWISDAVSGSAANSSAAASSLSSAFSAITYSPISPPLLLTTFFLLLVNQHPQPIDDCPCFEDAIASGAVVFGALLGRWATAYFHLHDLIERLGGPKPMLGAGWNIVNVNNDNDNVWVPIDRGFKDYTLFAFIAFAKILLGVTFIFIWRLFAKSLLGLLLPPLFRLVARVVGAARVKLGMRWLGMPNRRFYLPATEYRGPVPNGFIGMEEGEVEGDEYELGRRMGSIPSVIDLPSTLTVGVEIQGGIGSGFARDSHRNGNVGREIKSRAGNGSSKLSNEVNAEEDIAYTPDGNEDKFGSGSGMRKHIHYDADVLTKILVYAGIAILSIEVTPLVFELLGWGVYVSPPEGVLVHSVQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V477</accession>
    <name>A0ABQ8V477_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_577110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13545" checksum="18F9944EB90868B2" modified="2025-10-08" version="1">MQRTGLRLRDRLRSPYAYTRNQRYSTQKPKSPHAQWYSDVLPSMVPIFLLGSAVYLGLQLAQTRLFHEKYMIEARERVETLESQIDVALQRNREREPDTTPSKSPSDKSSWRFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4N2</accession>
    <name>A0ABQ8V4N2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923927</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15275" checksum="A5D24CA4F0BDEC73" modified="2025-10-08" version="1">MFNGGCDWNLTEVRLKATSRKRNRTFTSLASSQRLLMSQPSTPDAPNIYLANTAGEVPSRQMIIEPWTKQQMNIVLLGETGVGKTDLVNLIANVCAGATPENFVEKIELISHVSMDTKSTYHCGEERVLAPPKSIHYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4T3</accession>
    <name>A0ABQ8V4T3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="30909" checksum="1B01458023619E15" modified="2025-10-08" version="1">MTEYDYSPEGYQRYLDTQRRISKWVQNTNAHASEFRSPFGTFNPVRVSEESSSSRTRTSTVSSKPHGDRNIIERGRGMDDRERRHSMSATTFRQGASGASNVDFHTQRSPAHTSQVRHSYPYSPAPQESYTATRTAYAAPTQSRRAQSLSSPPSQPQSRHRTHHHHHNAPSQSAARASRPHKLDSPRRSTTPPDSYHRHSTHRPSSSHRSNHHHQHHSRSQSTPRPSSKLGSPLAVSPAYAVVGGRAYVSNPRGYLVIPPKGKKLSVVVSHSPRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6C6</accession>
    <name>A0ABQ8V6C6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_846774</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="10">
        <location>
            <begin position="51"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4475824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="358" mass="39532" checksum="109FD52D5118A6FC" modified="2025-10-08" version="1">MANTALKTFSIENDIVELSPQDDIYKFDPEADRKINRESPWSKDPHYFKSCKISAVALIKMVMHARSGVPYEIMGMLQGKVVGTSLVILDSFALPVQGTETRVNAGAEATEYMVAYYQGSQSAGRPENLVGWYHSHPGYGCWLSGIDVSTQMNNQKHTDPFVAVVVDPNRTMTAGKVDIGAFRTYPENYTPANVASSEYQSIPLSKIEDFGVHANQYYPLEVEIFKSSLETQLLDLLWNKYWVNTLSQSPLVSNRAYAVSQLADLNQKLSKVQSSVAGTKASLPVSAKDLKDVKQKELLKEEKKKENELAKSVKDSNKIAAEAQHGLIAQIIKDVIFSIRPGSGQADTSQIGESMNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V768</accession>
    <name>A0ABQ8V768_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_904808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="80"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="449" mass="49323" checksum="BF258ECA31C7584E" modified="2025-10-08" version="1">MTQIHSPETVNSNTKFVAAEIQRILAGKLFDTYQLQFLPSQTIIVSKNTGIILNVESTNPNDLDPSQMSSGNTIDLRHLTILPGFVDTHVHCKCLFCVFLHSYGETSWDDQTTKESLVERTVRATVHARKTLLSGFTTVRDLGTEGAEDADISLRKCLSGPNPLIPGPRYFCANRAIVCTGSYGPKSSLHMNREGLEGVTGAEVADGVDECIRATRRQIGAGADWIKIYADYRFRSRMNGLSPRFAGMPLPTFNELELGGVKVAAHASNTNTIVKLLELGIDTIEHGSTLTPHPDSLMRLLSTTPNTIWVPTLAAWQSVIKMFQRALAIGMDNIACGGDTGAFPHGENSLEMKLMVRLGAEWKKVLKWATLGGWECIRPMGWEVVNATDGSHDMPLGDNDHRFGCIKPGWAADLVGVEGDFEKDFEGTVDNVQFVMKAGRIYKLDEKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7F9</accession>
    <name>A0ABQ8V7F9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Frag1/DRAM/Sfk1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_844141</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050911">
        <property type="entry name" value="DRAM/TMEM150_Autophagy_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324:SF2">
        <property type="entry name" value="EG:22E5.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21324">
        <property type="entry name" value="FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4478536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="253" mass="29086" checksum="3C59AA3EE06E5DF5" modified="2025-10-08" version="1">MAIFSHKRHHWAYVWIPIVGAFIWFGTLWAMLITWLATGRPHYVSMAANQHVPFISDIAADILKPLFITSCTITAISFILDLIIERYLRHSGRLMPNMRTRERVFSSLAILGSLIGGAGLILLSIFDTRRHKTLHDSFLLVFIVGVALSAIFTVVEFRWIYKDFQYAPLLKRSYWMKAIIAGILIILACAFAGTEFKVVNVGGIFEWIIAMGFTFYLLTFYYDLRQSKGVHRGELSADRLNSNNRRYRMRQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7S4</accession>
    <name>A0ABQ8V7S4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_846699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="27367" checksum="8220DA326208A15F" modified="2025-10-08" version="1">MLPNIDFAKAHHVLQLKEYLSQADESIRRASIVGVSAYKITSTDDALFSKSLGKASHQFLVVEVMSEGESFYAAIHFGPDPFESYPVSQTVVFSNDLETMCRGCTHFCHMRSIGNAFSFEQFASLLSVVYERSGNYVVFSRNCYWLTSVLLLSITRRYSHHWLQGDIEPQCLREYANGQRDEISIISEIILPGEENGFLRRVVQTSLLGLKGLQVWISGFGSQETKVRPYSEEISEILENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7T7</accession>
    <name>A0ABQ8V7T7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Protein phosphatase methylesterase 1</fullName>
            <shortName evidence="6">PME-1</shortName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_510141</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Demethylates proteins that have been reversibly carboxymethylated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022950">
        <property type="entry name" value="PPase_methylesterase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="7">
        <location>
            <begin position="59"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4478520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="331" mass="36280" checksum="AC78CD16530D2ADE" modified="2025-10-08" version="1">MSHRTRKAKKEPNPAFAPISAQNFFVQAFQVALPGRNLDCRVYYTPPKFANGTVMVCQHGAGYSGLSFACMAKEITDLSGGECGVLAIDARRHGKTMSTSDQPDEDLSIGVLIDDFVEVVQTIYPDAQASPNLILIGHSMGGSIVTRACAILLDRKYTIGGVAVLDVVEGSAIEALPHMNSLLNARPDGFDSVEEAVEWHLNTKAIRNPTSARISIPAVISPSGNSSPIVPPFIWRTPLRSTAPYWQNWFVGLSHTFLNVRTARLLVLAGTDRLDKELMIGQMQGKFQMIVVPGTGHMLHEDDPTRLAEIMVDFWRRNERLVIGIKKVGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Z6</accession>
    <name>A0ABQ8V7Z6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_771987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06222">
        <property type="entry name" value="RNase_H_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044730">
        <property type="entry name" value="RNase_H-like_dom_plant"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4479433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15833" checksum="76C372484C5287C7" modified="2025-10-08" version="1">MGFWFHYDDKTLGYQCMIPDGHEKPIFYFEALTVVSAILHAIKLPFLPRVFVFTDNTNTVDMFHSLKAKQLYNPLLLTTVDHAMCSNIQFRVAHILGEENGIADALSRFDYTRVIHLAPLMEIYNFTPPQLVLGAEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8F3</accession>
    <name>A0ABQ8V8F3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_905096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="451" mass="50033" checksum="EA1D00F67B6E4682" modified="2025-10-08" version="1">MLLSPAGSNASLTSNSFWNKFKSKNKEPDLREKQAQMALTRTRLLTLAFGEMETIRTLPSSFSELEQAARDWARPPPDAIFSLRVPVEYASIHAARLVAGPYIYLTSEDSFQIAAMGAQGLRVEIVSDAPPPPDEPPPPPPPPVLEMPATFNLELVPGQHVALDTTVTSDELDMARMEDGTTVDGMFWGKLDIVHNGDDHRMEFSGTRLTNQQDYSPDFMFDSRVMTKLAVAAKPTTAKCNLSLLTPETTYCDVTLMFSPYWKPGTIWPPAESLGDNKVKYFLRVHPGGALEHFDSEVVSTALYYEAIPDAGMLDPDDVIGPRNGYAMSYRDFIPHLINVLDQLGMSLYARTNFINNNIAAFAAHKNIAYRFMSPSKIAAAVDITVTSEPCVFTRLFLIFRGLNDDEVGIFAGAGEKEANTVNWREVVTWSEDSKDPTMFRVLETSVLEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8R8</accession>
    <name>A0ABQ8V8R8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_489235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473">
        <property type="entry name" value="BTA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="382" mass="43869" checksum="9385F0DF053C63C1" modified="2025-10-08" version="1">MPYPHHTAMKTFIYSFTWEDPEVDIQHLDLASSDSVFAITSAGDNPLHYAIASSPQNMHCVDVNPCQGHLLELKLAAISCLEYSDFFALFGRGYHPRFHNLLETKLRHRLSLGAYEFWKRNVSLFSSSSFYDFGYSGRALRFVRFLFKLAGVRDDVERLCNCESLEAQVSLWQSNLRLVWLNPLVVAVLRNPAFCWNALGVPLNQRKMLLDEGGVYQYVCDTLDPVLSTYLLKTQNYFYLLALLGHYTPECCPAYLTRDGFEKLRADNCQRLNAFHLHTESILDTLRGLSSSSLTRALVMDHMDWYDLDSSEVRDEAVELSRVLASGGLVFWRSASRNPWYNQVFAENGFMVESINVRQHGMAVALDRVNMYASFWRAQKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V908</accession>
    <name>A0ABQ8V908_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_841686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045124649" evidence="2">
        <location>
            <begin position="20"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4481303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="23919" checksum="D2A06A66FAB38A3E" modified="2025-10-08" version="1" fragment="single">MGGCVLLPLFFLMLLTIGGQTCVATKDCSIYYSVLSRSFVRCFLGNSPNDNISALVNIQHSNFAFTSRVDFVVLDELVGCEATFGLQFRQTCSFLQCLGLFELLPDTKTSLEHCVPSPRLLSVIGLPGSLLCFPMGLVHFFLYFPTQKRPEIWPSFLPMMVKGFLLHPIMGIIIVFHQLLLWLICHLRQFLLLSYSICVCSVTLNQAYSVFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9B9</accession>
    <name>A0ABQ8V9B9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_499617</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF65">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4479892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="573" mass="66125" checksum="58C83C4FDE317D5E" modified="2025-10-08" version="1">MSSSDAESIKKLHEVDTVLADELTASDELLKTIDLAEEDAPFKLSSWLFSRWSSKPQLNEDDIATRRSVYDNPEMAQLYWPKQEYENLHRFDPTARWTHREERSLVRKIDWKIMAWAALSFSALNLDRNNLSQANTDNFLPDLDLTTDDFNWGNSIFRLAFLCAELPSQLVSKRLGPDRWIPTQMVLWSIVTLCQFWLTGRTSFFLTRALLGFIQGGFIPDLILYLSYFYTKNELPFRLALFWMSSNLCSIVGSFIAFGVLRMRGVLGRAGWRWLFLVEGLITFSIGVATFFRMPPSPTQSRTWFRPKGWFTEREETIMVTRVLRDDPTKGDMHNREGLSLKRLWTAVCDYDLWPLYLLGLMFGIPGAPPSTYLTLSLRNLGFSTFTTNLLTIPSTVAGMITMFAITMVSEVLNERTFVAMNEDLWVLPFLVALYCLPENPNQWVYFGLASGLLSYPYTHPIQVGWCSRNAGAVASRTVNASIYNMFVQATSVISAQIYRADDAPRYRRGNLTLIIICCFNVVVLYPATKAYYIWRNRQRDRIWDAMSVEERKEYLTTTTDVGNRRLDFRFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9L0</accession>
    <name>A0ABQ8V9L0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_841367</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF76">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_135, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="125"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="425"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4481787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="56018" checksum="A1C0F979CD234073" modified="2025-10-08" version="1">MHQPSPGPSSPATSVPSPHSLGPLQIPENASQKSRPDDYVYFERSNAGFSSEAVARATAAKLKLVSYYKMAVDSAIERNARRIELETKLSQTLQPETKERELRKHSKMESQHLRLRRTKIKLTDFKTVKVIGKGAFGEVRLVQKVDTGKVYAMKTLQKSEMLKRDQLAHVRAERDVLAESTSPWVVQLFYSFQDPLYLYLIMEFLPGGDLMTMLMKYDVFSEDVTRFYMAECILAIEAVHNLGYIHRDIKPDNVLIDRHGHLKLSDFGLSTGLHKVSDGEFYKRFLEEEKTRNPARNSVQVNPINLTMSREQIATWKANRRKLAYSTVGTPDYIAPEVFLMKGYGKECDWWSLGAIFFECLVGYAPFCSDNPGDTYKKIIDWPNYLFFPEEVFISREGEDLIRSMMTWADSRLTVNQIKSHHFFYGADWSALRHIEPPFVPHLQSSTDTAYFPTDDFGDMPDQLEQVEGISAEKDLAFINFTFKRFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9T0</accession>
    <name>A0ABQ8V9T0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_896730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007727">
        <property type="entry name" value="Spo12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05032">
        <property type="entry name" value="Spo12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4482731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="135" mass="14514" checksum="06581B6334A6A042" modified="2025-10-08" version="1">MSATTSPSESPIATPIQPLHNPANAAHVVVPQAPLGNVVNQVPGMGAKALLAKKMAKSQSAAYHSPTDNLMTPVTQKLNAVKKKHFAKPSKPVQLFAQKEENSSDVEVEETETQVSPLESTEDKMEIDNDDENPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA10</accession>
    <name>A0ABQ8VA10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WLM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_772856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WLM" evidence="7">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="314"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="244"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4477929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="376" mass="41354" checksum="28B6C91944FC6C59" modified="2025-10-08" version="1">MSEVYVQSFTHLKDRKSADRALEMLRRVASLVKPIMRKHSWVLPVLAEFFPDNPNLLGEDYTSHLLNLGGSLTKPDVNMGHQILVRLRPPHSPDSFLPEEDVVQTMLHELTHNVHGPHDEKFYKFLAELQEEYDALQRSGYAGEGFFSKGNRLGTNISHNIPPHLARAQAVAAAEKRRNLSQTLGGGGRRLGGDTEDRALSLRERAKRAAERRLLDEKSCGQGEFAQREADKAAKESVENKVIDLTLDSDDEPDVITVHNSAPGPSKIAVQPPEPVSPSSLPPRTTRAAPSSSSSRTGSQSKPPPFVNLTTKPLRDRWECPACTLINAAMSLQCEACLATKPSSELAGWTCLTCGESGMPHEFWSCSFCGTIKAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA86</accession>
    <name>A0ABQ8VA86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_921842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="44402" checksum="C969528C1D6A6752" modified="2025-10-08" version="1">MLSLPVELRILIYALYLSELQHVPGNQQPKNTHFRLLHVCRQISYEAGQLANFRSYVSLIHEDQIAAFNANISTEAASRILHADVANDSRLVHASGHSVPASELYLVLSKLVSLRRLRVFEHNRTRPMKDFILGARFTVEFEKAMFPSGRAPQLDSYELYLSPLKSSARIFQVVSCNSVQRLRLSGDCGLPQGTKLPRLTNLAINGVTGHYLEQHMEEYFAQCQLKEFQYTQGAKPGAYFELRDRHLNSLVFGSASGLHKLVLLGCSRLSSLTLTSCLRHLDQLRYLALSFVSVHELDSDFVSAFPSSLIVLKFSISNAWYTNPLLQEEHKLCDSVEDLIIKRRPPLKFVFVNFRDEVTAMSGRGKRWTRIAEERKFALQLGAWEEDEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAC2</accession>
    <name>A0ABQ8VAC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_840379</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="47"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4484072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="423" mass="45998" checksum="BE0E79BDD938DD61" modified="2025-10-08" version="1">MLSLARRSAPVSSTAYRALSVWSAVPAGPPDPILGVSEAFKADKDPRKINLGVGAYRDEHGKPYVLTSVKKAEELVASSDPDKEYLPITGHAGFTKNAAKLAYGADSIPLTQGAVAVTQSISGTGALRIGGAFLARHYPNAKTIYLPTPSWGNHTPIFRDSGLEVRGYRYFNKETVGLDFEGLKADLLAAPEQSIVLLHACAHNPTGIDPTHEQWQEISNILKEKNLFPFFDMAYQGFATGSISNDAFAVRHFVAEGHQVALAQSFAKNMGLYGERVGAFSLTTADPEEKARVDSQLKIVIRPMYSNPPLHGARIANAILSNEALYGEWETEVKSMADRIISMREKLYNMLTHDLKTPGEWGHIKSQIGMFSFTGLTPAHTQALAEKAHVYMTRDGRISMAGLNSGNIEYFATSVDSAVKGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAG3</accession>
    <name>A0ABQ8VAG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="6">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 90 kDa subunit homolog</fullName>
            <shortName evidence="6">eIF3 p90</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Translation initiation factor eIF3, p90 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRT1</name>
        <name evidence="9" type="ORF">C8R41DRAFT_797912</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="33"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4484017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="736" mass="85471" checksum="1C52F6C6BA0E69A7" modified="2025-10-08" version="1">MPGLTQNVDNIEDIDYSDIEAKYKVDYDGSFDNTLIVDGVPIIDNSKLERLLTKICKEFSRKGVPVKQDDIFMPWDEATGKSKGYLFMDFRNSHDANNALLAMNNHPFDAKHIFKLNRFDEIEKFANMDETYVEPEQEEYMPREHLRAWLTDPQGRDQYVVYRGDDVEIFWHGKPSQCELAYKPDWKDFLYVSWSPLGTYIATLHRQGVRLWGGPSWKPQQRFAHPLVKLIDFSPCENYIVTWSNESIIVPDGKPQGPQYFSPEDEGNNLAVWDIKTGHLLRTFPTNSGTEGPAGKRQMQWPALKWSPDDKFVARVSPGQMISVHELPSMFLHDKKSLKIEGVVDFEWCPLSDKDRDEVEKVASVGAKGAKKAPENMIAYWTPEVANQPARVTLLSFPSRTILRQKNLFNVSECKLHWQNQGDFLCVKVDRHTKTKKSIFCNLEIFRVREKDFPVEVVELKDTVTDFSWEPKGERFAIVSTNDPNLGNPGPGITIKTDVSFYQLDRVKNDFKLLKTLPNRTSNAIRWSPRGRFVVLATVGSSTKSELEFWDLDFTLEDRRDGQVVKEDWGSSIQSLGLADHYGVTDVEWDPSGRYLATSASAWTHTLENGYALWDFRGQELLKQIQDRFKQFLWRPRPRTLLTREQQKQIRKNLKEFSRVFEEEDQRESENVNTELLALRRRLVDEWNAWRARSTKELAEDGGHDHVKEKQSEEDKEEIEVWVEDIIEQIEEEVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAY9</accession>
    <name>A0ABQ8VAY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_921591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="32250" checksum="AB32742C3ADD284A" modified="2025-10-08" version="1">MVLSGYSWKQVGGLIQRIGHTFGLNLTSEMSRRTVSRAILEGGVAVKLQMGYEILNTPGMTLSADSTSRRKQNYESRHIALQVPDYAELKNSIHVKPASYHRVCFFVIEATNDHSSQGSPSVSIGSSPFGIFSVSFLGGTEIMLLAKRHLQEESEKKLAKEELADVILYLASWNAKKLEEVGGIEAWNALTPQEQAHRDVALMKEILDDLGQKEYDNLPEQARRNLDRFIWAGCCMHKDMNSFKGGNSEMMAEWAELGVDPPVLLANEANASILHKVLNPGLKPCHKVAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBC8</accession>
    <name>A0ABQ8VBC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_442098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052587">
        <property type="entry name" value="TELO2-interacting_protein_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057567">
        <property type="entry name" value="TPR_TTI1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049362">
        <property type="entry name" value="TTI1_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460">
        <property type="entry name" value="TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460:SF3">
        <property type="entry name" value="TELO2-INTERACTING PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24181">
        <property type="entry name" value="TPR_TTI1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21547">
        <property type="entry name" value="TTI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TTI1 C-terminal TPR" evidence="2">
        <location>
            <begin position="484"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4485164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="821" mass="90507" checksum="99A4625A5CE52D0B" modified="2025-10-08" version="1">MKSLSPLIQHPTSSALMGLAEFSAHVLRTTPTTLPQIQPLLLSYLLALTNSELPSVSGKATELLSELLTASSKARYSLTWTLMRITRDNLIALPVLLPSQSDTKVEHVTGIIEAICRLALIGKDNTKSNLSPIAFEIGKLLGPTGGVEKWGWSLLSVLELVDPPVTVTSTSAAQMMLENEPEVSAWLPFPQPMLKNVSSMNTFDSLVRMFHALGKAAGDAGLFAVEWFVNIGQSGKDFKAVTGMWCACRLLEGISDVSLSEDPSTSLRLSRSKRLEKLARGLVKSTAQLWDSIHEDDPIDTPSEGIPDGHDEVPNPIQHVRGLIRLHDTLQITRGTPIGPRITTQPLLHSALSVQLISITAGILETRFSPLFIYSLYPILHSLVSPFSFLAETGLRALTFVTVCTSYASPANLLLSNFDYVLDSVSRRLSRQWLDVDATKVLAVMIRLVGSDIVERAGDVVEECFDRLDEYHGYEIVVEGLVEVLGEVMKIIKFEELSKLSNDQTPPVRQSCIDQQKFDSFIEWFAHRSESTVEEDQEDYGPAPRKGWGDDNPPDKANTGDQPEDVPEVMPDEEPPLTSSQALTKQIVQRSIYFLTHESTGIRARILNLLSSSVAVLSESTLMPSIHSAWPFILNRLADTEVFVVSAAAGLVEALVTSMGSLMFRRVWDDVWPRFRSMLSKLETADKINAVSHRIRGGVGTESVYTHSHRLYRSIINTMTAALKGVDPQDSSNWEVIVAFRRFLHSEAAEELQQCVQKLYLAAGTVNADAVWLALTATSGQVTSTSTKFLYESQWDIVKNVELILVIELSSSEVISIVLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBR6</accession>
    <name>A0ABQ8VBR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_846291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="39593" checksum="0DAC510A43A90311" modified="2025-10-08" version="1">MTITVEEAQKVIVKTFSKSQLWHVVSISEVENIDSYSRTRIHTTYILDLASSADGTSTHTSFITISTAAENITSAFPSNSPHIFAQLITMIHKGTSLPIPEPILDTTLSVISYPYLLTPPQPLRSNSIITISAARSQNLLTAPQEAFIDRALGQFLGQLHSGVQNDWFGPPSISQPVEPSYSWQDTFVALLEPLLEYAHDSDIDLGAPYKDIQTYLARAIAAFLFEDVEVPSLIWFTGSEDDIYITRPRDTSPSIQIAAIVPTLAHSLWGDPLLETFFLPPAPSEVVKEGYADGGGNPLLVFARQKTKRLWYTIFLALVVLVEREGIQITDSPFNKRPWALDALKRCTRALKDAPCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBW0</accession>
    <name>A0ABQ8VBW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF757-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_884578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3560.10">
        <property type="entry name" value="yst0336 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023139">
        <property type="entry name" value="PBDC1-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008476">
        <property type="entry name" value="PBDC1_metazoa/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021148">
        <property type="entry name" value="Polysacc_synth_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410:SF9">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04669">
        <property type="entry name" value="PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide biosynthesis" evidence="2">
        <location>
            <begin position="16"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="20676" checksum="C1569F689E5A4876" modified="2025-10-08" version="1">MAGKFDPQNAQNLVEIEKQFAVKAVEQAQTYWNLLAKVQPKELRLTKLDDEIFQHTMEAFPELAKEPHENLTRLDEEWMKSAEGKERWRKFIMSYEKKIKDHNFGSLIRMNARDEYAEKNTIFVTRIQFYAIEISRNRLGLNDKAHEMAKEEVEKERLQKEQEDAKKKKKKASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC41</accession>
    <name>A0ABQ8VC41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_489053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="146" mass="14985" checksum="BE7AAB75182BE6DC" modified="2025-10-08" version="1">MSVAVPPGLYQVQVTSNTSQKVAGPASAGGNITVNTSTSQVVSKQGSGWQITGDGVITSFQTGSSATQARTPNVPAITGNNVVANAGTIAQQWIISGANLISNTYWTGYVMTSDGTRLFWGVDGSNNVLVTGTSAKTQFNFIPIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC94</accession>
    <name>A0ABQ8VC94_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_460058</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17947">
        <property type="entry name" value="DEADc_DDX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="208"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="395"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="631"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="559"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="647"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="709"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="731"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="756"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4484105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="766" mass="85231" checksum="444707614BB8FBAB" modified="2025-10-08" version="1">MSGYVMTIDSDTEETPSETHPLKEIKDEALNPDFTFDLSGDPYSDLLEERKNGPDILRGTRPEPISVDDIIARRKVAKRKREHESDEEEEEGDGDGEDSDGFDGSHEDVSDEEDDPLATSDEGEDEDSGEENAFGPDEADLSDAESSSDDSEPETQAEKERKAAFFDSEVGPSDAHESFLTMNISRPIIKSLTTLGFHHPTPIQAATIPVALLGKDIVGGAQTGSGKTAAFIIPMLERLLYREKGKKAAATRCLILVPTRELAVQCYDVGIKLGTHTDITFCVVVGGMSIKSQEASLRNRPDIVIATPGRLIDHIHNSPSFTLDSLDILVLDEADRMLSDGFADELAEIVKVCPRSRQTMLFSATMTDSVDELVKMSLNKPVRLFVDPKQSVARNLTQEFVRVRAAKESERSAMLVTLCKRTFKSNVIVFLRSKKLAHQIRIAFSILGMKCDELHGDLTQEQRLKALQQFRDGQVDYLMATDLAARGLDIKGVETVINYDMPGQVEQYLHRVGRTARAGNKGRSVTLVGEADRKMLKAAIKHGSDKDKIRHRIVPQDAVNKWAEKLESLKEEISEILREEKEEKQLRQAEMELKKGQNIIEHEAEIFSRPARTWFQTEKEKKNAEAISKAQYEAGQKTSSGKGKQKAPVEEAKPKRDKFSGLSRKAKRRKMAREEDEEMGNEGAIKSAIRSAKKGIRPSKIGEPERRPVKTSKTKEKKKIRRKLTLGKGGAFERDLGQSRHEGARAKKGDVIGGMGKKKGSKRKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCB1</accession>
    <name>A0ABQ8VCB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_435942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF0">
        <property type="entry name" value="PCI DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="212"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="409" mass="46921" checksum="029018B52AD71E8E" modified="2025-10-08" version="1">MDFATFLSQINDALISENGPNLAYLLRPTSPHGKSLVKEFRSNATQGSLEPAYKGAIRSPWDDIAIKYVLTCTCVAKRRSQEAYKEHSALVLLFLRFFTENRGWTLPALFSILRDLRDLAFDADFHAKYNGERSECMEDAARKIASAFGNCITDRQSPPEQSRKWGVYYVVALVLKCYFRLKRISLSKNILRALEANRDIPALSQYPRSHQVTFRYYIGMLHFLNEEHAKAEEELTLAFYHCHVGAHANQERILAYLLPLRLLKGHLPSDELMKRFPVLSEMYTPFVAAIRLGDIAAFDRALEEWESKLVDLSLMLTVERARELCLRGLFRRVWVASDKNSRIPVSVFHCSLRISGMDVDQEEAECLVANMIYKGFMRGYISHEKQMVVLAMTNAFPKLVDRPSPFAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDN5</accession>
    <name>A0ABQ8VDN5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_896530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18744" checksum="424F85B54CE8FDA3" modified="2025-10-08" version="1">MASTSSSDVLILALGVALAASYLFRDILFAASKPKVAPSATRSLNDTDGNPRDLVAKMKAGNKRLAIFYGSQTEEYAICLAKEAKAKFGLTLLLMQNLQDESFEFSKGAHDLYGLKYVVFGLGNKTFEHYNVISQYMATRKGLYGSFENGGSSTWLLGSSIMECSVLGRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF09</accession>
    <name>A0ABQ8VF09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_833463</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00807">
        <property type="entry name" value="GlnRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="14">
        <location>
            <begin position="190"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="15">
        <location>
            <begin position="497"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="16">
        <location>
            <begin position="601"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="702"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="704"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4491869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="766" mass="85892" checksum="58126F2980982D32" modified="2025-10-08" version="1">MAAGTLTLSSKLTPFPYSAIAIAAYTEKSEIVYDEAATSVLLDLNGSKIDTEEEIVHALAKAGGLSEDSAKAASFFALAKTLRTVTAVPEIVTGLDSLDDHLAWRTFLVGHDITSADWILWGALKSSTKIIGLLKNGKHAHLTRWNTYLESLDSTQAALAGLTAAKANKARGTKVAAGFALGLEGAEMGKVVTRFPPEPSGYLHIGHAKAAMLNQYFAKMYEGKMIIRFDDTNPSKEKTEFEDTILEDLELLEIRGDIVTHTSDYFDQLYDLAIKMIETGKAYADDTEREQMQHERREGIASAHRDDSVEDNLKHFAEMKTGSTEGLRWCIRAKMSVDDPNKALRDPVIYRCNPQPHHRTGDKWKIYPTYDFACPAVDSIEGVTHALRTNEYRDRNPQYWWMIDALGLRKVKIWDFSRLNFIYTLLSKRKLHEFVNNGQVRGWDDPRFPTVRGIRRRGLAVEALRQFMLLQGPSQAIVSLEWDTIWALNKKVIDPIAPRHWAILEDKKVTVTIKGGPSAVEVKILPKHKKNPDVGEKKTVYSATILVDQEDAKSFEDQEEITLMDWGNAIVRSKSVDATGIVNSIEMDLHLEGDFKKTKKKITWLSQSTSEYPLIPVTLLDYDYLITKKKLEENDNIKDFITPVTEFREFALADANVKDLRKGDYLQFERKGYFIFDGENKEDGRLEFIKIPDGKAANLASKAAPSSQAVPASTEGSQPSVTDGGPVIGDPESVTKMYKTDKVYGDNVNLEGPVTKMYKMESIYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF50</accession>
    <name>A0ABQ8VF50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="46233" checksum="62D8113ABA4F7DA1" modified="2025-10-08" version="1">MSLPPPQHLHCLHVNTTTSIFASIFASISASTLPRPCASPPPPPSPSPPRHLRQDRLARGCLHLRLHLNTSTSASTSTPPPPPVFPPPPPPPSLPQDRLAHVCFHLRLHLNTATSISISASAFASRSPCPRVSPPPPPPQHLHLCIHVNTSTSTCVSASTSTSISASRSPRPCAFPPPPPPQHRHLHLHLRLGICIKIALPAGVSTSASTSASTSTPPPPPVFPPPPPPPSLPQDRLARVRLHLCLHLNTATSISISASAFASRSPCPRVSPPPPPPQHLHRLHVNTTTSIFASISALTSPRPPASPPPPPPPPQHLHRLHANTTTSISASKSPCPCLYLHLYVNITTSTSTSPPPPPQPHLVHIHQLHVHLNSHVHLNVTTSRSRLPLSMSTSARPSAQGWLVSLLWFWTYESHIAFNIQCCKAQACKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFD1</accession>
    <name>A0ABQ8VFD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_840795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4483164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="30945" checksum="0E0FA2DB896C7738" modified="2025-10-08" version="1">MLPPGPRRIQEDQNGDMAVVTPLRKKTQEDQDKADEQARHKALKDLVQSWQDRLQLITLITTFLASVEASMLQVTMPDDPSNSSKWSQAANAGFMASLVLHLHASFVSFFASFFLVRFKVQEAKREEREVEAADSSLHHVPTSKGSTILEMAAHNITRSPTTSPRSTVSIGNGAFPPEKGNAPTPKNQIPSIWSANPQLVQTGPFQRQPPINLLSRCHTLCLVITALGFILAMVGVLCYAWDGQSTSVAIITSASICLCLLSCICIVLPQQSAPSSRLFMYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG89</accession>
    <name>A0ABQ8VG89_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="53273" checksum="DCAC54C1D74FDE56" modified="2025-10-08" version="1">MTKPGLSAWLSVLDELAIGRDSMLSVSPLSEVGGAGTIRLVDLTAITTPMLDDTDTPADTTSITSAVPQLEPSSHLTCCCQQDDCSNFKAWKAIILRLENNFILSAEAGQALLQHYDALRLLHQDCSANNEDHDHQFSELLDKNHSLEKTCLLVDTDTETQRNLYCMQKLDLALINNEAAEASAFTLHRELDEARATITRLSANHVDVTTLGTRLSRLNGELDDMQQERDIALIKVSVNESKLKLSMEKASELHSENRRLRKELRQKDQLHMDSNESLLQGAKSKIQKLALNATFGSTATSTLENAELTKALETVYGHNENLKRHNDELQALLADAQDEIFTMREEVQVHLANPPIQRLLESNEDQKTWGASTSSLKQDTDPLNPLIPDPCAYQGNEEQQGEPPIRGLSEFDRDEFNVQIEPELPFVERSMSEVHDLKGQITIDPKSKANESLKESIGTTTLIVRFCISNHANQSNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGF4</accession>
    <name>A0ABQ8VGF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_830673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="44231" checksum="43EF7CC63AAC6E41" modified="2025-10-08" version="1">MPSLQIQTYTLSEGIELSFTDSGVPPGSADYTTVIFLHGGIFNAYQFHKVHAHAHAQNLRTVLLHRRDYAGSTSYSATEIEELEQGSVTFWERLSAQVAQFLEIFIERERIPKLTRKLSSSRETACSFTATSVKENRRGNGGIAILAWSAGCSTVLSFLGGTQNPLISKELYQLLQQYVGNCILYDPTYLCFGYPLPSDNRNYIPWDDPTVSTDELPQLVAEWVSSYYDHPCYDPVTRSLPSTATMNELDGIRLKSDRISISSWTDEELVKGLERSSAKNETLVFQPSVQKTLRQLSEQALFNKTSVSNWFPGVGVSYIGGTRSNWMCAWAIIETKRRYLRTLFTGIEKNGRSYNIRKIRFVDMDGLNHVAHWDQTREFMEVIAKEIQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH36</accession>
    <name>A0ABQ8VH36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="660" mass="73034" checksum="03295A6FA66C22D0" modified="2025-10-08" version="1">MASTSSSQTRTEVSATLLPTSLAEAQELIAGLKSTSSQPFFFESDLFKRLSEGDYCPPLLNSQNSPDHDSSKPFPAFSYPSALVPFCFPPGSSRHLSVASGLDLFCSTRMIIQILHPLIEVSDSMDSGEAYNAFEEATPFLAYIHNFLIGRANCPLFAEHVLRTADGLFQHLPAFLRDSLEQQWGIPFNHQSSFLGPSDFKQCPVIPIPFCLRFQEGSAMMRLASPKDLDPFVSLRSSMAETRLLPGGPRVPSPVEDSFESSEENQLVAPPKCNKHKCELAGLMADASTILDRHSNVKSPLKEDRPILPKASSSKKKVEKPVPKPKATARSKTTVKVVEESRVSPESEELVTPSYQIKCVRLPPCLRQAAKGKARQMEVLDVAESESEEEVLPPPSKRLKSSKTAPVPSEASNFHPALLIDDQGHLKLPGDSAEGFTPFKRIEHARNSAPLQRQNPIFDVNPEFLDLGVILTTQKASFTMQDLLQINRTIRDPAIPAQACVSALSRGEFNPNSSHLPGLKYVDLAMDALNALHVATTSSTINLTNSLRRTQELRTQLDRLGTVFDQARQSFLRSFLDLQHAGQDPIVVLEALKAAEPQRESLSVEDWTLLRREILSTPLSGSQRSFFTHSAYFDLLYDHFDQFWVAAFAIPFNLIAKLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH53</accession>
    <name>A0ABQ8VH53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-keto sterol reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_883244</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051593">
        <property type="entry name" value="Ergosterol_Biosynth_ERG27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647:SF1">
        <property type="entry name" value="3-KETO-STEROID REDUCTASE ERG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647">
        <property type="entry name" value="DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4491726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="46973" checksum="51DFF67E57BB9767" modified="2025-10-08" version="1">MSRPIVVVTGANSGVGFGICQRLLCQLTEKIPSDILIKPRNLFGNSEKNVREADQFVLPCEGITLIMACRSVQRAEVARQKLLRILDERVEALRKGSGYDGHAEYFRKNVQIKIHSVNLSSLETIPKFVQELEASYPYVSHLMCNAGIAPFISINWPSCIHQLLTDPLGAVTSPIYYLQTWGEVSQDGYGFTWQCNVFGHYTLYKDLYHLLSSSKYRYDSRVVWTSSLESKKTYRAEDWQLKETHDPYGSSKYQVELISAELDRRVLDEPNASKRVRHFTAHPGVTHTNIDLNLINPLLHYLKHFIFYLARWIGSPNHPIALDKGAVSVVWLSIISLSTLTIFSASNKGSKDDPLSNKSGSRSGVRPKLKFAAQTDRWGHSCVGVSEIDGGEKYSEEGKALVDNCENLYQGIKVARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHP5</accession>
    <name>A0ABQ8VHP5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_763288</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STE7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="321" mass="35767" checksum="A5AC98800EE71CE9" modified="2025-10-08" version="1">MGNGGSVMKVEHIPTGLIMAKKIVLIDAKPTVRKQILREIHITHSCNSPYIVSSFGAYILDPNICICMEFMDKGSFDGIYKRLGAIPIDVVGMVAASVLEGLLYLYDVHHIIHRDIKPSNILLNSLGEIKLCDFGVSGELINSIANTFVGTSVYMSPERIQGAEYSVESDIWSLGITLIELAHGRFPFYVDDADEEFSAQLTFGSSREPVQRDMPDMLAPPMSPASRRRSRRRSKGVSLQGGIQELSILELLQQIVMEPPPRLISSEKDEGKFPKAADVFVNACLIKEQRDRKPPAELLNYEWIEQTLTSGLQMKKWAESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHP6</accession>
    <name>A0ABQ8VHP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ARM repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_305982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the API5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008383">
        <property type="entry name" value="API5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12758:SF19">
        <property type="entry name" value="APOPTOSIS INHIBITOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12758">
        <property type="entry name" value="APOPTOSIS INHIBITOR 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05918">
        <property type="entry name" value="API5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="45841" checksum="1533E12A87F9784B" modified="2025-10-08" version="1">MEERELQVLVRRTKTISDKTGSSRRSALKQLVQATRSSNASLKIFAANNIPDFFQDFPEAEEDAINAVYDLCEDQMSPVRMAGYNALVQMSRLEKKWVKRNADVLVQLLQSDDPNEVAMVRKALVDHLQFDSRVTLGVLCDQVVPPDDLADPEELAMRNSLRTLVLSFVIGELKKGQLIRYMAPGSEAEDTLVNGLISAIPKLDETDTQVILKDILMQLQFLDTPCPRGATLSQSVLQRAKSALFDDHMNLDAQNGTRSLNKTRPYLDMLSVILISKRQGNLEDLFNFYTPILGKTVLSSISTEDQLIVLRHFAEALHACKSNPPSVIRLLNLTPFFFECLSKANLTQVIPQKVCVLLLRGLLLVADNGWVIPPQVLHSAQSLGRIVPSLDQGGDIHELIRVRKGPHCLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHT3</accession>
    <name>A0ABQ8VHT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_308021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046027516" evidence="1">
        <location>
            <begin position="17"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="153" mass="15905" checksum="E81F45D7E4D258F3" modified="2025-10-08" version="1">MLLFMLSLWLLSAAHDSSNLVSALAGGMAMGSGSETTSTSAPLNFEPITDPVTPNEVITATVSGSPPPFRVVFSNSKDGALVTATPTIIASYFPISTESDRAGFTLTVPSLSVGEDVVYIEYISSETTPFSINTFPFAIGTVSVVVTSNSPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHW9</accession>
    <name>A0ABQ8VHW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_828795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="85"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="325" mass="34345" checksum="073FD8A022AC7191" modified="2025-10-08" version="1">MADQAEFAFIKTFVNTVSTQPITYDDEYQQPPENSLKKIPVLTGVAVPEPPARKVEETAAGSSSSERFKGVIAVSCTKSAHIATLNLLIKSTKPPITYTLSGIHPTDTISAIKQHLSTTNPTAPAPDAQRLLLKGKALADNKLLKEYPVKDGDTINLMVKPGVEWNPSGPAAEPPAVTLSTPAPKPAFGTSLSSSLLSGGSPAAASGHTGKRHQRIPSVVLSPSPSNEDDLDAQPRKDVLLTLDTTDLALGTGSTPKETLGAYHLTISSPGFWDKLIQFLRTEFTSESDALTAFEDFLAASKGYLSASDIAKIRDHVGVMGMAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHX9</accession>
    <name>A0ABQ8VHX9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="334" mass="37711" checksum="C43DA3FBD1617EB2" modified="2025-10-08" version="1">MVFNQRGDQLLVCSGADVLLFNKTSGKWKYHDCLPRPIPFGEPSEGDTYPIVATGLDFLENENECLIGYLYNGFWKFNLETWESTLYFGPDESYELEEPRRYFGRITASAQSPDSKSVVATDTCIGLTWFKVMPERLKKMSQAVIMGTTKGCALILEVKRAEKLQALKHGNDQTWVTSLAYIDIDGRCRMIATGDGNCEQRTRIILWIEEDKKDISFKFPKLWYIMPKLNWAGSPYHDGIDLRFLTPSPLWSEATSEKFSAYFFKSSSLAAPFPSPSPVIPATSSPFLTKVTKLFDALGELLVRVNSPFTGGFLMKYCQGISETVITWIPGCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI70</accession>
    <name>A0ABQ8VI70_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MICOS complex subunit MIC10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_828685</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Mitochondrion inner membrane</location>
            <topology evidence="2 9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the MICOS complex subunit Mic10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007512">
        <property type="entry name" value="Mic10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304:SF0">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04418">
        <property type="entry name" value="DUF543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4495329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="100" mass="10580" checksum="485322B8FD2ABD71" modified="2025-10-08" version="1">MSSSKPVSSEDILGQKYDRCLADFLVKTGVGFSVGVVASVILFKRRTFPIALSTGFGAGAAYADCDRSFNPARIPGTRIIPASSSVSPVVPAEPEHKHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIG8</accession>
    <name>A0ABQ8VIG8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_827990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="231"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="637"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="749"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4495437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="861" mass="95791" checksum="F1CDE009A6B868AE" modified="2025-10-08" version="1">MDKLIDILAAFDAGKLPSHHQVVNFLEWLKKDIISDGAFSTQGRIVAQRLRDVATAYQLLGEHKNKDNLLQEAIWHLSQGDISDTSVDVDIKTNTDEALQDAQDARESIRTILSIIWSGLSSESSSLFEDFTSFARLSLADAAEVVEKQASRAKGSLREVDEEVQSGKRDMLGRDKERLKQEEDLQVAFEHGMDTVKDAGSSVIGAGQQSVAKASDLSDRTSAKLHNAFYKMCERAQNDEEYHQSLDTLFGTVQKWISKGFNTATNVASSLDSLVDDNTADKHIAKALQAIETLLSRLAHTDSLSKLVSTIRKCAVDVRDDQDLRSWFDDFFTHLRRDLDESGYIRSDESKRVRKDLRTRWKDMLDQDSEFGRTWKNDVEAMKCQIQKIQNGLKSDEDLNRLRDAHLKLGEAIETGLIEVGDQAQTGMQAIVEQLTWFWQDLFRVYLPRALSMMKDIPIPRTEYKDAESELVLENLDVSSFNLLPSHMYIRNITDIDIVAPASASDAAVQPESKTQLGTLTQIRIQAIQLAVSDISFYYKDKTATIGPAEYTGRMSLTLPPKGIDVDVKMRLIPASATTTLAPVTSSASRNAKVTPGSSLTNHPVPAPFATATKTVSQRSLHRAFHVIEHLDVRITDEFELDIKDSNHGVMIAMFKPIMALRLKSALEGFVSDHFRQIFEGLDGLAYDISERAQIFKDTGLGSSASIGAAVWSEVGRMRRLGLDSRRRGQYTDWQATGTGVVVAERQVDLETGEDKERERKFAMGAEPQILSGEKKGPDGTASESLSKRLRSATGQALDDTGVDAGAMPDVTDTKQISEQAKEIFEVGKDQVKSLKDAVKHKSNVEKHREGWQSSAFDIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIQ8</accession>
    <name>A0ABQ8VIQ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_980354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056948">
        <property type="entry name" value="PNGaseA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25156">
        <property type="entry name" value="PNGase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12222">
        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045085351" evidence="1">
        <location>
            <begin position="18"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal" evidence="2">
        <location>
            <begin position="37"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="60221" checksum="69EBB30E7DFCD32E" modified="2025-10-08" version="1">MFNTFCCIFLILSLTSGTVIRDFQVAQPPVVPVYAKYCTVEVFSHDFANSFVAGPAITQLSPPEDCGPVGSWAAITLNLTVTTNGTQFDRLGIFTFHNVEIWRTSTFEPTIGDGIVWTYIKDVTQYMPLFTESGEFLLELDNLIETGLDGIYSTTVAATYFESSAEYPPAEKADIIIPISTLSNTTADDASVPPAFSLNITVPNNTVAVYAEIFASGNGLEEDWFFNVPDEFFSNISPNITSPHDGFREVRLLIDGLVAGVAFPYITVFSGGFIPSFWRPIGSYGIAELPTYFVDVTPFVPLLTGNSPHNFTLDVVSAEATHTINPNWYVSGILQVILDTSFEPTIGNMTVHSASNYADTSITGSVEDFGQFNATVTATRNIHIEADILSGSGQLTHVIWTQDLQFSNIQTYRNNGLLATLKQTSTGNSSSTHNGVAVLSDVFSYPFSTNFDYLDETLSNWTSSIDHSYDRILLPNPLRIASTINNHQTTDGFFQLGSEKIGNFGNGTNNNTFSYSDVKGNTYTRSVNAINSNFNDTIAIPFDKIGGNLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIR1</accession>
    <name>A0ABQ8VIR1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="54477" checksum="66D62DB35EA2938F" modified="2025-10-08" version="1">MADEATEETALLQDVSSAHLPLLRNFISRLNSITPENLVQTDVLQPAQLSNHRALRTSFSIIVLLLFREQKTREKASQYSPWDDWKHELLTDQWVKTIDENIEQIWTTFLGTFCSSRDVEIVLWTEFLVDEKGKAFRVIDFVSKHPKLLNDRVVELALKYRWKGGALLDPSSSRQYLTSRYDVLCTPWIYHSFDLASQIAFLLLLIFYVLNPPHPAFFSLPLEYIGYREVVLIVLSIAAILHSWTASMPFALTLAAFVLNLPSAPLPSEYSFNILLLSLVLLLIQLHLPLCPSPFLLIRPERCLPLAALIVNSVFGPIMKVLLFFLPVLFLSVLFLSYALSDVFLVSSFVLVPAPIPTRELFFILVASTFIIILLSVLVLVPTSISYVRGYSSWDQYSASNGQMARAQFYRSVVRYSKPYPFPPPFNILYFVFILVPAKVLPYFDISNSFLSILEKILWRAIVGPFVVIVRFLTLGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ35</accession>
    <name>A0ABQ8VJ35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="236" mass="26000" checksum="7D01292B89A1323D" modified="2025-10-08" version="1">MNSNSGYSDVHGVVPSSICRIPYDRIELRSSTTPRPASVDRRILSSPGAFRTPRATVRTSPYHNSRSLSPDPSFKPTSIAVELTSCDHSTSSDTRFEDMPTLANSQPRIISTRSASFGVEKTAGQDGLGDESDSDDKIAKPLGEVGKPSRGGYNLRIKLGWADDRFDDVEKFINGLIERKLNVLQPFAQQDPSDIKELQDVASRKIFPLVSRVLILYPSGFKKVPVSPRVSWLLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJI9</accession>
    <name>A0ABQ8VJI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_981387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="625" mass="65727" checksum="2F6B22D2E1409EB9" modified="2025-10-08" version="1">MSSIESTDVDLVTTLVRRQGEELLKVRKDLEESKKLYTTAVDVVSTSKFRVENAIRTSSQWQSKFATMISDLSFLQSEHEASLAELKATCTELRATLGLFNSRDVPTIVSAPESPISNANPVVLATPEDPVDGYTSESSISDISVDEKELEHDESHETHISVNSVEVVAGDFVNVAAVETELESVSSQDSVLDDVPGVDDSYVEGDDHSNDAKVGSSVPRSVPQSLLSASTATPVLETAIATLDTVLPAPLAPVKTATAVPDGTSESDKPKSNEPSIAASFPKPASLALGPNAPAVPESSNATFNRLNGASFSSSVFGRSSSPASVPTVTPIPQSSNAISAQSNGTSSVPVPSTSTAPATPKGSNSNPPVPAMPKASSSASVPTASPVPKSSIPLSAKASASVPATTATPVPKSTNPITAKPNGPPPVIATSSSVQGFSLANTHLSMDSAKPICTKLPAVHTRKVVKDMCLKAIGSPGKTTYHIFNIPEVLLAYPSGRNLALITVSKRANEVSSNLTKFSRQWKGHVLSQNSATKHLFFLGEFQGGASYKLSVNEYNLLPAKTKKCVFNAAKSLRYQDIQDQNQMLLSMGKDNGIYVAKTELRFTSDSSAIEAAMRQEATTRGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKN0</accession>
    <name>A0ABQ8VKN0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_824935</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="96"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4496831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="543" mass="60319" checksum="B38BCE561E88CBFC" modified="2025-10-08" version="1">MITRTSEISQSLSPEPDVEKLPLNLSEPHTSLPHTLSSTGHSGVTHQGKLGARPKRRHFFSALDPNYAEAVNLDAENVVYTFEEDTRIKRKIDNRVLPLIICSFIFNQFDRTNIGNAHIIPAFNKNFGITDNNKWTLALSIFYVGYCLLEIPANVLQRHIGANRFFFLSLTFWGLSSLSIVYAKGYAALLVLRVLLGIGEAGFYAGVIYYLSFWYKRHELAMRISLCMTATYSGAIGGLLAFGLVRADTALLDGWQFLYLVEAIPAIIMAFVTLFFLPAFPFSASFFTPREKAIAQARVNRDHRPQSHGGMTGWQGLKAVVIDPNAWMFMSIYASFNVGVATIPYFLPTLINDLGFTAINAQGLTVAPYVLGWGMVVLQAWHSDKTRERGWHIIFSCVISFVGYVILATSARKSVGASYFALFLVVGGLYSLFPLVMSWAANALSPTSKRGVGTAFIVSISNTVSIASPQIYFDPEDDYVKGHAISASCLFLSMLMAFALRTRLSWLNNRNAQRLSGMSEEEKALLPAVNEMDDQDPRYGFMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL43</accession>
    <name>A0ABQ8VL43_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HMG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_760355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040648">
        <property type="entry name" value="HMGXB3_CxC4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18717">
        <property type="entry name" value="CxC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG" evidence="1">
        <location>
            <begin position="31"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="311" mass="36040" checksum="71199501C480871C" modified="2025-10-08" version="1" fragment="single">LPPKWCLLESDEPLYPRPLVLRQVQETIYIRNGEGTCACRDGSRRMYSSSLPTFLRECTVYTLSRAIRTNIELQKCSSCERRYIGPETRTLGLFNLNNSLLFTHELLDEYISAFTSSETPFDAWVQQVSRRYQADDNSIPFVGADTFRAAWFAYARLINFEGDKQCERCGEAPENVVWDGVTLAYARKQLRTGLRPPTTVDADSPIHPRTVGKKKEWFEDGVARKRLHHWIAKGGMGWGNDEKDRMAAEERQRDYPGIVESLRCMNKDLAILFEEHLGVKVLERNGKWRPQREYKAFFEMVRLIFLGKIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMK9</accession>
    <name>A0ABQ8VMK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_213027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="2">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="193" mass="21715" checksum="3579C2EF65C20E91" modified="2025-10-08" version="1">MHVSLLFADGTCWAESGDSAGHILTSLVDIIDPNNVDSSICAQFGTDFYARIRTIPTDSTPHGCPGNLVHLFLEETGGYWWGERNGVWEWISQTDVQQLERVFDVCYVVLAQCDFPSQCDFLTRCHCLAYNKGELIRITKECSDGWWWGEMDNNSGWVWLMNVKGEENISWDIIDAGGQSSDDEGYETPEEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN38</accession>
    <name>A0ABQ8VN38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_979482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="337" mass="36590" checksum="3B69B7B136EDE021" modified="2025-10-08" version="1">MNNHSQNARNIDSSSYCFTCSGVVTPLKPRIRPVMQSSAMSPVELLPSRASTIPTISDRSLNLYNKSPRAGPDISPDLTFLTLSSASPAVKALLSNQDSDLHIGSTCSLSEAFDTPPPRTPFRPSSPSSPNAPVRIDWSAFPVFDATVGPTIGDTSSNCPLFCKPRPMLPRGGLFDLSAWPPRSPADESPELSPCIPSRKAVRLRRSTTYRPLNMVKSPSHRLSSIQETSTSSQWQTENGSRPVQSSRLLALCSSKLHKRSTVSLVVDDDYDSNDGRSKPSRPPLVAGFLQSLPPFRLSATPSSTSPISTSPVTPSRYATPLRSPFLIRKRGEFRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN78</accession>
    <name>A0ABQ8VN78_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histone deacetylase interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_918239</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="6">
        <location>
            <begin position="547"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="196"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="881"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1345"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="896"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="915"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1366"/>
            <end position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1376" mass="153746" checksum="9A2BCBABF8F520DA" modified="2025-10-08" version="1">MDDAEILDNANDAPLTQINATPTSAGVEPDTENTKISEPAPPVPSPSIQTDELPQKVPVTTAEGALEAPKSSTNSQEVEMADEPAVVSVSSVVLSVKDHEEDNAMQVDRPLNVTDALSYLDAVKNKFSTRPDVYNHFLDIMKEFKSQQIDTPGVIKRVSALFQGHHSLIQGFNTFLPVGYRIECSSDANHITVTTPRGTKMETTGSGGGKPFHWSDEPEPHSPIHHPPKHSEHRERRILPPSRRGTPDISLLQAPQAMEPAVAYVQKIKQRCDPETYRQFLDILSRYHHSPESINEEEVSKQISQLFKDAPDLRSDFRIFMPDGSQSLLDDNAAAEEGRHHHHHRERDHHDSKSRRKADVADSASASVLPQKRKRKAGERETIRVEREKIPAKPITSNKSKKAKTESARSALSSVPTNQTALAAGPSSARIPTSASLPNSSSQLTIDPSQFFDRVKRALDSRDTYNEFLKVVNLFTQGYIDTARLVKESRNFLVGDGELMRGWKEILGWDGRKEESEGWEDADGWSRPVVVDEVIERPTPIPGRVDLSAQYGSYRRLPESEINVTCSGRDSMCRDVLNDEWVSHPTWALNSSSYGSASTSNNSSGNITYPDPFDDPTFFWAVSRKNVYEEALHRSEEERHEYDFHIEAISRTIAILEPINNKISQLSPEERGGFRLKPNLGGSAKAIHQRVVRKIYGREVGTEVLACMQESPAHAVPVVINRLKQKEEEWKRAQREWNKVWREVDARNYAKSLDHQTVNFKAADKKLLTAKAFVSEIETAREEQMASRASLVDPLFSRTRPRHQLEIDFEDLNVLQDSLKLVLSFLDRTQGQIHWTERRRIEAFLRGLVPLVFMLDAGAFNAAFAVVLELGGADGEMDLEGLGLPDVEAPLPTGSRSGGGRSKKGGGGNGVSGGDLRKKLLKSEQAKSGRKTRGGVASQASPSVSRFASPAPHTTVEGTPKIVPTTSRKRGVFFTNTTFYVLLRLLGVLYTRLYLFKSISAQLHEEVGQSPSGSYSPVHYQPISTYDATSSMISNLRGHEDSIVSEQPGDIDVHTEVVPSLSFVPAGQTNEESESFQIERERLDPTAAQSYDILLQNCERLFDNEIEQSAFEDQMRSMFGVKDAYKIFTIDKLIGAIIKQVQLVFADSNSQDLLEILKRDRAMTSPTSQDQVNNRRNAEKVLGPDENLFRIDWLTENKCLTIQLIGKDDSSYDDSEVLTGRWQTYIDSYVAGESTEGISPQRVKSPFLKRNLPGPEHILEPNIVGSDALEIKVCVRTYRLFYVSDTEDYLFGMRRKDDYAAILPSLHRRTQARMAWIERSRIEQPQAIDEVEGMNPFTIAVTETRPISRTQEEVEANGQGEKDSASTSVSVLTSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPC3</accession>
    <name>A0ABQ8VPC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="450" mass="51289" checksum="0B79CE6CD8C3A616" modified="2025-10-08" version="1">MSYLTPAQILDAAAYKYASGEHQAPQYRASTNMGVIPAQLHKESPYYSTPRTSQVESPISSHYAGHTSRHDSNASRPAHHHHSATSVQRQRSMPMMGFSGGPSHAPSIPVMSFGSHDPNPSMSSVVPAPLSERRNSQDTVPFPECTHMTRKGGGGGTSNAYPNYLNLPPEYRSASQDTQRQFEYPDYLNLPPGYGRNSNNVQKQNKYPDFLNLPEEHRTSQSQHVLIRSSGYPVHTQNPYPFTSPSHHPAQSIAPPKRRRGDPQLNRYPPDPFPIVQDGRGPTNHIRVPQRVFYDETDLNRCMSYSKPITFKMKNFAELGVRLFDCLDENHFRHPNIEDKDAKLFSTDEVYREMRLKILWPGYSEYPFTRRINIRKGEMTRISMLFNIATAIADFVKKVQSDRDCTCERGLEMWQLTGRERLNVDQFILTGLVHRGGPNWQPEIWCPTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPT8</accession>
    <name>A0ABQ8VPT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_818919</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="11731" checksum="F4970995E7D3BD0F" modified="2025-10-08" version="1">MATTFAKFFNHPAGPKTVFFWGPVMKWCLVGAGLKDLNRPADKLSVSQNLALTATGFIWVRYSFVIIPVNYSLAAVNFFVGLSGITQLGRIAHHQYTQGQLTAPTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPW3</accession>
    <name>A0ABQ8VPW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_819007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="416" mass="45558" checksum="D6EB247335EC23B5" modified="2025-10-08" version="1">MASSPTKVIIVGCGVAGPVLAYILKSKGFRPVVYERIKRDSDGGISLMLQSNGLRVLALIPGLLEQLPGQVENHMAFYSTVPGHEELLGEHTLETPLDAVGTMNNSVNSVGMGIRRHDFLHVLSGTATKAGVEIHYEHKVVDVQQEADIVHVKFENGTTDTASFVVGCDGIHSNTRISLFGKEEASYTGLTQLGGFSPSPKSWTHKNAMVNYFGEETHMISYQIGPDLNSWAITRREAEHKETWRAVDDSILEELKKDPVSKWGFGAGELVQTAKKMIKYGLYDRPELKTWHKGRVILIGDAAHPTSPHLGQGANQALEDVYHLVRVLLKHSPSVGEPSTGALKNAFEEFESIRLPRTSSLVKQARQTGEKTRVIKGTAACLARNETIRAIWANPEFSVQSLANARSGPFDGESEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ94</accession>
    <name>A0ABQ8VQ94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_901536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="258" mass="27280" checksum="76752C892A184839" modified="2025-10-08" version="1">MALGFTSSSSASSSSTSTASASTTSSSSSSSDNAGIPSKGASYFFGFLITFIVLLAFFICCGFGTRRNMARRRALLAWGQWDSRSVIGLEGQLDSSDVPALFEPRFMKSDNDAFWLSVQPLTAQTLTISSTSINACHDTTRPLPPPSSPGPPPIRLPSQNPHALHGLSLPAWIPATSLNLSSNNGVGNEKRNGKGVSKPTNAQNDVTVMQVAVVIEMPSRPRTEKGEEDGVQQNLVIGVACEAWDSSAYIHVTEGAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQF0</accession>
    <name>A0ABQ8VQF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease-III-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_756359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040030">
        <property type="entry name" value="Ribosomal_mL57"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28160:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="18"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="24163" checksum="658E6EE2E5C7DAE1" modified="2025-10-08" version="1">MFAEHLNHLFPELQFPLELARRILTHASHPAAIYGHNAGLSFMGRRVISAYLYLLLSSSPHLKPSDDLEAIVAQTLNTYVLGEHIGSKWGLGRVMRWTPTLKADKSKDASPTLLKGVGLYKVQGDAVAAVIGGIFEQFGASTAHRTFHTRVLPHILASKSHAGLPEAFHEDVRSACNRFGGLQGPLVIDSSSLPLLTTDAKIMVADSVRKEKETTEEVSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS20</accession>
    <name>A0ABQ8VS20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_743305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="111" mass="12758" checksum="90206E91751A925D" modified="2025-10-08" version="1" fragment="single">KLRMQNSDLKSQLALAKRHKNLGKTVGNADPNINHELVVKLAKKYTVMVYPWPTSNLFMSFPPNDLPDPESPERFKDESAFEAGLINELHLYLNDRDLRKKAAEYSPFQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSQ2</accession>
    <name>A0ABQ8VSQ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_63317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="63395" checksum="933429CDB8BE7721" modified="2025-10-08" version="1">MSASDPPDEIEKHAISERWRTFSSLPTTQLRAILTQEQIDIHILRDKLSTAEKKVAMIKTILSPFSRLPQELISEIFHFYCATQGVIYDAFQKRNSRTRPSKVDPDRIVSGVFTIPPQMILTQICSYWRTVAHETRSLWTNLTVYIQTGKFTHHEQLIENWLNHSGQNMPLDIFLSVPKGKGQATKSIMLGIIPFADRWRRLELSAPFQTIRLLLIRTLDAPLLEHVRMNICHITESSMLAYSMDVTFVSDGYYPAFHNAPKLHSFDCGAIFDPDTYHEDTFSFLTILPQPQQLTRLAMNGNAFVPSISGGFSLLGVYAHTLVSLSIHVSRETPDAEAPFPLTFPQLRSLSVVASFPFDGDHFFEQLTLPVLETFEFTIEKDCFMNDQAYTKIIDMQARSSFVLKEIAICNALNASNLCTFLEMQNSLRRLSLSALHSCKLQNVVSWLSNKPSALPCLQELHLLGGQLKMGSEDPWKGLEDIMHGRAQLPGEPMGVYGNLQLLDIRMSKTAFGRMDQDELNSLQQYRDLGLDIRFHIWLSNGTLVDAVDHLASRTFTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSU0</accession>
    <name>A0ABQ8VSU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_929341</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007191">
        <property type="entry name" value="Sec8_exocyst_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048630">
        <property type="entry name" value="Sec8_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20652">
        <property type="entry name" value="Sec8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04048">
        <property type="entry name" value="Sec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec8 N-terminal" evidence="7">
        <location>
            <begin position="179"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec8 middle helical bundle" evidence="8">
        <location>
            <begin position="467"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1228" mass="138770" checksum="3621F9FBC8D95206" modified="2025-10-08" version="1">MSRAPPFPTRQNRSASVSRTNITSPTGSVSTRPLQISRPTTPNNNSYASESALPTNGPSRPQRSELRSRNSETDRNSISSNSTASRTVRTSPTGPRQPQRQRTGDSDINDDATSPTLNSVLSAFQSAGTRRRAMTNGSDDYEYQRMRDEERAAEMVRQQQYQKRMAGKKGPVRPRQGDIDAVLNQVKDGWEFVVDPDFNPVDLAVDLLDQRSTGKDMNSFQDTKYKLFSALKGTVDKYYQAFAASLPHHASLLNHLSETQNEIDEARTSLQESKEALGSKRADLVQMWSRGQMLEEMMHLLDQIEHLKTVPDLLETLMSEKRLLQASVLLVRNLKIINKPEMQEIGAVSDLRSYLLGQETALREILVDELHGHLFLKSFWCDSRWASYSPNQRTFPKVEFEDEPPTVLPDRSPSSPTFLATRLARFLQDLTLRPNDAPMDVNESNATIPSVASLNYSASSRPQALLNPEADSFAYLETVLESLAVLGRLGSTLDIVAQRLTSEIYSLVETTIDEVSERAEYGRRNSMFGLSTHKFEGVYVFSSDPSLVVQHQGYFPGSSLRLAALEPSTQQVDQEILRDFFWTLYSKVDAVSQGLRVIYEVANRIGSRREFKDSTGTKPGTLFPLVDIWISIQAEMKTLVYDYLTNEDEGVTSGRNPISSINDTLREGRFSRDRTKSFFRFADTDVKLTNKMLRTHEDELTQVLKDTMPGLVQGPTENTAQSAMLTEDRILGAGQHHRLLIKPNAFHVSVLFEPTLAFLDRVRSVLPSDIESVAESGTVLDEFVLNIYLPQLEDKVSYLFHQAITGPEAFQPDPLSKRISPEPLIKVSTHLMALINSLCAMLQITPFHRESYSRLILGVVIQFYQRCSDKFQDLVSSSPSGDLLQPQVALAAQWAQRTELMPCLTELQNTTEEDISQQQQLWRQETHLEQDFLDQRRMASTDLIPSIRNLVYLAGMYRSIIWFARELNALKAHPEDAPLSPQNLEPLSATTMPYTPLVAYAPIVSPTNQLSLTLSKEMSLRFQALLRTYEQLSELILHTIRVDIRCRTVYYLDLAMRGNYSLDGEAGEPDPHVIDLNNNLSECDDHISPSVPLNARRFIFSGLGQLMEHTLINGARFLRRPNVYGIRKILRNILALQQSVKTITVNSNENFDRAKRYFSLFFLSPTDMLNGIQQHQEFSFDDYQTMLALQCGVDPNPSDPRQSLASQATDRNYSMYVIDLHGLEIQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSV1</accession>
    <name>A0ABQ8VSV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ima1 N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_814125</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042321">
        <property type="entry name" value="Ima1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018617">
        <property type="entry name" value="Ima1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538:SF1">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09779">
        <property type="entry name" value="Ima1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Ima1 N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="62993" checksum="75DF5B6D86C7F2AE" modified="2025-10-08" version="1">MFRRPPQAQCYFCNTFLPHPKDPRNFRCNSCGCWNRYDAKGEILSDEPQMHEESLNVKSFSKRASPSKDRLPTSYGSGPFCHNCQTNQHLIINLLSNYLPPPTSPEYEQRLEMLPRYRESLHTRYPPVCESCLPAVEEEIRKKDAMARAHALGGWLKETKGKVRQRRVSATLQERENIPKELFAWRVRGCLWAATLGSFLAGYIAILSGWRPFDRPSLLQPISPILTLCSILWTAWDPTYASIRTAQMQGRDVRVQGKRHYNALQIIIWVFRLITTTLLALQWFHIDYLQLSQRPLGLPARLYFLFLVLLEISVSIVSFFVLRIQQPPTIRLINTKTHDLNNSRSPTPNPTDQTSRASTPAFLPKVSEPDLFASLTISSSQPVVPKSLPVFGLPSLLPSSAPIEADDEDKMDWTPTNVNPGTEKFKVPSDSIGKDDGWWLRPQRFFAPEKPTGLESLFENTKLADDVPMKDVTAVPVNRPSVLRWKTHIEVWWWMYTAVLVLLMGVSLKLWVGRNGTSVQQDFHHISSDNFAQDPIQQSGVYRHTSRTSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT12</accession>
    <name>A0ABQ8VT12_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_754411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="205" mass="23118" checksum="FB9C0912D006AA09" modified="2025-10-08" version="1" fragment="single">CDIIDLDGKAIPTTRERSTYTHAQKMRAAATFGFGRVHGLGMQAWHRSEISGKTLGNPSVSETVSTYMLSLRRRKTQSGDTPTSARAATSVCMLRLSSSFVLFHFNRQPQPSLSPTTKGHLGPRARLMMNCGYNFAFCGLLRVDEMLKIQLQDITFEKNPMTGQTKLTLRLPFRKTSQFGGEWQQGLCSMYSDINYFRHQAFHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU94</accession>
    <name>A0ABQ8VU94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ClpX ATPase regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_752949</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="121"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="5">
        <location>
            <begin position="363"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="483" mass="52860" checksum="F5A518566518CC7C" modified="2025-10-08" version="1">MVRPSTRNVRTQPSYNGPVGHDPATNVPSFKLATPRQLVEYLNHYIVGQEHAKKVLSVAVYNHYSRVFANEAMSQQQHSQSELGHMPDDSNTGVQSAKIRPLRYQPPSSSSLLPSAFPLFEKSNVLVIGPTGSGKTLLAKTLARVLDVPFAVSDATSFTQVHILPHVGEDVEMAIQRLLQDAQWDPYRASTGIVYIDEIDKIARKSGSGIESSRDVSGEGVQQALLRMLEGTVVSVQAKGSQSEPPSLPGGEGHSRSGHHAPNVAAAPKPDVYYIDTSNVLFIVSGAFVGLDTIIRQRLSKGHSAIGFSTKSSGLNRSPLFFTPNQKTSDHVLESVDPADLVKYGFIPEFISRLPSITTLAPLTIPDLLQILTGVKGSLLSQYKALFQYSNVDIRFTSAANDEICRQAYERGGGARGLRGIMEALLLEAMYEVPFQDVQGVLITERVVRGEAPAQYWRENDGSPVTFWEAWASEETAYEKRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUA1</accession>
    <name>A0ABQ8VUA1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_752950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="752" mass="83669" checksum="E527C0FEFBDF5B38" modified="2025-10-08" version="1">MPVPVPHHSKQPAHLVIKQHCSDDGVNHSFQDLTGILPASPTGPPPSFGTREQWINSLPSWRRSKPRRIWEDDSHPFTEQDFQTGLARADNASAIKGSRAKACPPPFYIQHSTIAPTIKGAATSIDMVPHGPFDTAGMHANDKACSIATNMEIDVYDNPDRGAFTPIFEDDSPEFRSLHEVSSSPVEPVTPFGDFVDRAVSSTSAALSCSYVSNASLAGAAKDTFQLQCYRSHPATQPFTDLPVSVSAPELVTPTATSGYRKLSEPLSEWIAHFVWKACTTGTNIPSSIAQVRLVTPKAYAMDPPSYLATSIHSLLLSTLLQPSAIFLALWYIVRLPVSFGTVSMTADHTKELRFRMVLLGENHRLNQDVTDNTAPFRLIVLGCMLANKWLDDHTFSNKTWHSISNVPIKILNELESLALDIFAYDLSISTADWSDWLLHVMSYHLSLSSPSHPQPISRPSANPHLIIKFALEEIINAPKAYDSNSAQPRAVFLGLEERRREKQEKEQAQKANVLEIDLDEDGPLREEYMPKRRVSEAGAPHSVENSFSTQRQIWETNKSAEKQLPPPARWSPAGDEPILRDSNRPHGRYLAVQPTPGVLVPVTSYQGLPQYQSTHEFNYVSQPWLPNVQFATAKPLPTAGHFLEFTSHQHPAHSVFNSCPPPLLLPFALPHSRSQSYSHDQDTSQSYNHTRSYSQSQFEYRCCDLCMTPNELPPVQADVDMTWGLSGRHSYGPPAFAPHPSVTYQSTWLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUG8</accession>
    <name>A0ABQ8VUG8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_570647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16267">
        <property type="entry name" value="HBS1-like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04093">
        <property type="entry name" value="HBS1_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="420" mass="45527" checksum="10CFC790F62D27C9" modified="2025-10-08" version="1">MGRMLYELGRVDEKTRMANERGSNKAGKSSFSWAWSLDGTAEERERGITMDIALQSLSTLHRQITILDVPGHKDFIPNMISGASQADCALLVVDAAIGEFEAGFDRGGQTREHILLVRSLGVSQVIVAVNKLDQVQWSKSRYDEICDFLRPFLVQSGFHPSKTKFAPVAAMQGVNLVTMDQEAARELRQWYKGSTLADYLDQLEPPARDIYAPLRIPISNVFKGSSSGAAVSGRLCGGVVQVGESLRVLPGDEIATVKTIEVKEESVPWAVAGMNATLYLISVDPVHLNIGSVLCPPTNLVPLATTFTARIIVFDIQIPITSGASIELFHHSRDVPATVSNLIATLDRASGSIIKKKPRVLTKGTSAEVQITLRTHSLSGPSVARPIPLESFSVNKDMGRILLRRGGETIGAGIVLEIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUH5</accession>
    <name>A0ABQ8VUH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_863663</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="535" mass="59624" checksum="A90C46C72DC99763" modified="2025-10-08" version="1">MALNVLTVLDLCFAVVGLIILRRLFGPKSLPLPPGPKGLPLIGNILDMPTEKEWETFAQWGDAFGDICSVTVLGQPLIILSSAKVAVDLLDKRSSIYSDRPVLQMGGELVGWKNTLVLLQYGDRFKRFRKLFHNLIGSHATMRQYFPAQELEAKRFLRKVLAEPDDLQAHVRRLAGAVILRISHGYKVQEHKDDPFVTLANSATEQFSLATSTGQFIVDCIPALRHVPDWVPGAGFKRKAKQWAATLIELVEQPHNFVKQQMLAGTASISFTSSMLESKQLTEEEEFDLKWSAASLYSGAADTTVSAIYAFFLAMTLYPEVARKAQAEIDAVVGNDRLPTFADREHLPYVDALVKEVFRWKVVTPLGIDRECEARRVTNTDSDGTAVPHRATQDDVYDGYFIPKGSLLIPNLWKLTHDSRVYHDPFEFKPERFLADLLATEGLGRQVEPHPRETCFGFGRRICPGMHFADTTVFACCVTSLAILDIDKCNENGVVIEPVNDQTSGTISHPKPFKCSIKPRSPKAVALVQSSDEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUT6</accession>
    <name>A0ABQ8VUT6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_811840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046670">
        <property type="entry name" value="DUF6540"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20174">
        <property type="entry name" value="DUF6540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="21530" checksum="755A4AF4FC9A3D21" modified="2025-10-08" version="1">MICEAMSTTNTNPSRTLTLELIVMFPQIVLGLNIVRPFPDPAFHWFLFVANPMSTQGEGTKFYVTDSKNGVWEFEVVTNFAINSSSEAITTALIIGQIPEGTLKDVTGLIDICEHQIKLNEVPTADKGKEPKFTCRVWMKEAVRCLNAAGYLRCTDVDELEKEAIARGCAALEEIDGIDALNIPCNKPSTFHFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVA7</accession>
    <name>A0ABQ8VVA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">C2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_877071</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04044">
        <property type="entry name" value="C2A_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04045">
        <property type="entry name" value="C2C_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04040">
        <property type="entry name" value="C2D_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037761">
        <property type="entry name" value="C2A_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037762">
        <property type="entry name" value="C2C_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037756">
        <property type="entry name" value="C2D_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056910">
        <property type="entry name" value="TCB1-3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017147">
        <property type="entry name" value="Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24920">
        <property type="entry name" value="C2_TCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037232">
        <property type="entry name" value="Tricalbin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="226"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="422"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="565"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="692"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="1086"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="1307"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="872"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1269"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1442"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="879"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="926"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="949"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1287"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1309"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1442"/>
            <end position="1470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4499154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1481" mass="161959" checksum="DA74675593434588" modified="2025-10-08" version="1">MAGDGNGAVNGAEDQLKHDAAKGRVAVHNFDPDASPAQKAAAAGKAKDQLKGVQQKSDEGGEREVQIDHGNSNVIPTINIQDVDGEKKMQHTDGNVATDLDDTTPSPPGAMPAIPAANVPEWYQVGWRAVSGIDIPPLPEGEEKDHSVLNAFLGEQFYGDWYHNAAIIVFAVFASHFLTRFRFGWGWLFIILAVCNTYYTTSMERTRRRSRDDIQRELVKSRLASEHETADWINNFLDRFWLIYEPVLSTTIVSSVDQILSTNTPAFLDSLRLSTFTLGTKAPRIDKVRTFPRTEDDIVMMDWGISFTPNDISEMTPKQAAGKVNPKIVLSVRVGKGLASAAMPILLEDITFSGLMRIRMKLMSNFPHVQIVDICFLEKPVIDYVLKPIGGETFGFDIANMPGLSSFIRDMTHATLQPMMYDPNVFTLNLEQLLSGTPLDSAVGVLQITLNSARGIKGTKIGGGTPDPYVAIAINNRDELAHTKYKSNTYNPTWMETKFVLVNSLSETLNLNLYDFNDHRKDTLLGTATFELAQLQEDAVREGLTSPLLKDGKDRGELKYDVSFYPVLKPEEGQEVPDTKVGIVRLTVHQAKELDHTKSLSGDLNPLAKIYLGNSDTAIHATKCIKHTNSPVWEEPHEFLCADKNSSVITIKVIDDRDFLKDPVVGYMSIKLADLLTAKNEARDWFPLSHCKSGKIRLSAEWKPLNMEGSLASTDQYTPPIGVVRLHLDRATDVKNVEATLGGKSDPYVRVQVANVTKGRTEVVNNNLSPVWDQILYIPVHSLKETLLLECMDYQHLTKDRSLGSVDLHVEELAVEHDDVEFPFKSTGVKEATDQIRLDKGGGFKGTLHYKAEFVPALKLKGGVQFNESGTSALTKGVSGSSSSKDSDAGSFRSVGSKADEAGQDVPDGVTISEPSKKTHNKGAKSTDTTATNATSGTVGTNGTVETSDDAKGESHDDVGVEMSKNELLAQQSGIIVFNVVSGRLAKKARVEMLLDDGYWPCFSTNRARSTKASWGFVGEGFVKELDFSQVWIRLNEAEEGDKDDIIAEWRGDTKGFLSSTLDNAQTFTLNDSDERGTSTVTLEARYIPVPVVLEPRESINNQGVLNVTLLDGRDIHAADRGGKSDPFAVFTLNGQRVYKSQTKKKTLNPDWNEQFPVSVTSRVAADFNVELFDWNQIEQAKSLGFAQIDLAEVEPFQATEKTLTLTSHKHGDKGHLRVRLMFQPEVIVKSRKNTSTFSTAGRAMTQIGGLPMSAGKGVFHGVTGILKKGHKGDGSDDSSVPDLPAGQQSYPVGTSELATSAGNPFPPSSSSENLPVSSNSEPGTLRVTVIDAKDLAGGDAKAYAVIRVGDKEQKTKHSGKTASPEWNESFNFAASSLTPKLYVWIHDHKTLGKDKLLGDAEVDIWRHISSEGVTAAEVTVELHGGSGLLRLRLEFDASANPLTRRSSTSSGDRANTSRTLSIASPSRFSISGRRRGGDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVI5</accession>
    <name>A0ABQ8VVI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PinX1-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_893064</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF31">
        <property type="entry name" value="PROTEIN PXR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="282"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="382"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="411"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="463" mass="51100" checksum="22AC271774817377" modified="2025-10-08" version="1">MGLSGRKIKQRIGPDPRNLTWADDASKFGANYLAKFGWDSSKGLGVEGQGRTSHIKVSQKLDMLGIGAAQSKDPNGIAWKQNKDFESLLRRLNENNAASSDSGAQVIDVNAVNIREEEGINGDDDVEKDGKKENKEDRKKRKKEAKEAKKERKEERKRKRAESVDEEVEQPKPRKKAKADTKVKEEPKVEKAEEPKRIIPRHRAHRARAIAAKNISSKSAVHISEILGIASSSSSSSATPMTAATPSGTLTPLDQDVLGLVKLTTSTKSVSEYFKERLLVKTSGNSSPLSSTVTPETNARAADDSENEDTPRVGLGSYPNLTRDDLDDTPRGGLGSTRASTKFTSAASTFQSGISKFASMFTSASVIAKEETIVQVDVKSVDNIIRDTDTREDRKRSRKESQKKEKESRNGVAEVVGEPGAVDVDDKARKMAKDERRREKAEKKEKKKRHKRELLETIENSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWB7</accession>
    <name>A0ABQ8VWB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bola protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_810218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045115">
        <property type="entry name" value="BOL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735:SF27">
        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735">
        <property type="entry name" value="BOLA-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="86" mass="9687" checksum="92F84118B9157F88" modified="2025-10-08" version="1">MINLADLEAAIRTALPVSHLEIEDQSSGCGESYAIVLVSEAFDGKNTLSRHRFVNDLLKSQIAQMHAFSQKTFTPKQYEDYLAKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWE2</accession>
    <name>A0ABQ8VWE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_892711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF7">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="38"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="2">
        <location>
            <begin position="169"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="37742" checksum="94A583DB78BB4912" modified="2025-10-08" version="1">MAPITNGRLIFKEIPSGYPVPGKTTVYDKSSTIDLENAPLKGSILVKTLVLSVDPYLRGKMRAAERESYTPPFFIDEPLYNYGVGKVVRSENPAFHAGDHVYGMLDFAEYFIPKDITKLKVIVRPESTLPYSVYVGAAGMPGQTSYYGWKEYAKPKAGETIFVSTAAGPVGSLVVQLAKQDGLKVIASAGSDEKVKFCKEIGADVAFNYKTTNTAEVLAKEGPINIYWDNVGGPTLEAAIGNSALHGRIIICGFITQYNDEEPYGIKTMRNVLANRLSINGLLVFDHQERYLDEFYEVIPKKLASGEFKYTEDITRGLEKGGEAILEVQKGVNTAKKIIVVADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWR8</accession>
    <name>A0ABQ8VWR8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_750990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="439" mass="49354" checksum="335A360E06F8BE77" modified="2025-10-08" version="1">MGKLYDLPVEIIEEILLQCDPIEVGIISCCSRLFYDLVYNSPGDSSQHIWRALYLAQPFDDPTRCVSQNGRPRAGQFDWRSELQAIIRARTVLEDVSICKPHERIQVLKTLLNMVCWVPPLGSYGDIIENLSQNLLWVTAVTRGGVFLDPGKIGLPSDDPELAEEEAQLRARLHTTIGLTPADYKPASRLAARAYIYNMGHYNWSNEFGPFLPSSTEGSAVGRVNWVHMKHIHHSMTMHMLELADDAGFEVVIYPLSFPYTQIIIPEGIDLDQEDDWAGVNGVWTISFCFVDHALLLRYNNTPPGPFRESLLTGPGFQEMFRSMKVNLQVTNVMEDQNHPGRPRIYFLGAVADPSPSTSTINGYVCMTDDDQIRWHFVSGEQGQAIWSSEGVQVGGIRSSYGVLGSWTTIFHDDDDPVGPFWLRKPPQERSMFSATSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX88</accession>
    <name>A0ABQ8VX88_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_807553</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="62739" checksum="AE02C67D6D00E9C4" modified="2025-10-08" version="1">MSDPKASSIGILGSGAAGLITAYTLLRDGFTNVTIISRDSKPGGVWSDERVYPGLTINNVYGEFRFSPQPSLAAKDDSKRLSGFEMRDYMKKFADNYLEGVIRYGFHIIGVMRPSNNSSSGWNVRVEDVRTKQQQTLTFDRIVLCTGGCSEPYIPEEISPKSAKHASFKGHVFHSSQFRTQLDKLQAEGKDERGFGEVVIVGGGKSAQDVAAYLANKGVRSSVVFDKADAFLAVTSPLPDAIRRSRFLSILSPHSSLNSRLERFLHTTSLGSTITHFIWNKIIAGSFDAAGVTKDSPLRNTQDAFWGVRINDEGVPKPNGFHMLVKEGKIDIVAPARVASYSSDGESVILNNGGKLKADTVVLATGYTSSWHPLFDEQTAAGLGINRHPPDPSLVKSEDKWNNYVSLSNPPAAHPSSEQWASSIYRGIVPAKNLFNRDFAINGAVFTTNNGYAFEVTAHWISSYFLNDSNLKLPSSPEEALAHADRNSAWLRKRYPDMLLWANESYSSNLAFWTWPQVIDEMLSDMGLKVYRSGGSWLTWPFKVIELKEIEKLKEERDELRLETES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXB4</accession>
    <name>A0ABQ8VXB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase activation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_892868</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051025">
        <property type="entry name" value="RhoGAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228:SF25">
        <property type="entry name" value="F-BAR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228">
        <property type="entry name" value="SPERMATHECAL PHYSIOLOGY VARIANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="65"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="43881" checksum="17F1A543DE8048CD" modified="2025-10-08" version="1">MVPELPQSPPTKANLRAWWNTFTSAQKVKRDGEGKGKSSADDTSDEPENAVFGKPLKESLRYASVQISTANANGELYVWGYIPVVVAKCGLYLKENATEVEGTFRVNGSAKRMRELQTIFETPPRYGKSLDWKQSPYTAHDVASVFRRYLTRMPEPVIPYEMYHGVTKQPFNQEEVIATYKRLIRQMPRANQYLLLYVLDLLSVFARKSDKNLMTATNLAVIFRPGLMSHPDHDMNPKEHALSQKVLEFLIAQQDWFMLDIPPPPTNESGSPTSLVSEEDVTVFPSSDEEHQVGGGWKLVGREPKLSRRKTTIEPRRPSTQEGNLSPVAESPPAKQADAEGGALGVTRSRTLPSGRRGPSSSESTNATEREARRVLRKQKRASSSQPSHKGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXX0</accession>
    <name>A0ABQ8VXX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Laccase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_288378</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13903">
        <property type="entry name" value="CuRO_3_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045357881" evidence="7">
        <location>
            <begin position="18"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="30"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="158"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="373"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="523" mass="57168" checksum="921E3053712F839B" modified="2025-10-08" version="1">MLPITLGLISLLPFVSAELRNFDLNIVSTPLAPDGFERHVIAPNGTYPGPTFMVNKGDSVDIAMHNQLVDPTMRRSTSIHWHGFFQARTSYADGPSFVNQCPIPPNTTFHYAFDTAGQTGNYWYHSHLSTQYCDGLRGAFAVYDPEDPLGDLYDVDDESTIITLSDWYHIVAPEAQAGFFQTGTVPIPDSALINGVGRYVGGPEVPYAVINVEQGKRYRFRVFALSCRPFFTWSIDNHNLTVMELDGVEHDPVTVQNVDIYAAQRISAVVEANQPVDNYWMRAPPTGGAAGAAGNPNLNPNLTLAIVRYAGAPDAEPTSNNTGILGTKLDDANMHPIASENPGKLGSAPPDIFFELNIAQPNPPFFDINNISYISPTLPVLLQILSGAAQPTDFLPSDQVLLITPNATIEVSIPGTGAHPFHLHGHNFDVIRQPNSNVTNFVNPPRRDVTPINGGNTTFRFKADNPGAWFLHCHIDWHLEAGLAVVFAESPSLNLEGSPFSQTTPQDWNDLCPDYNALAPELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXX1</accession>
    <name>A0ABQ8VXX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="186" mass="20347" checksum="A6A171F154DDC14C" modified="2025-10-08" version="1">MSSLMPPSATTASSPTHLSSPDNEAMQVIYRPPGRPPRFVGLRRNSGEVPRLAHDPKDQRFEAMTERIQSQCNFLASVFSLERRVYGVKAAYYTVLVVIEDNQPLPAFMSSMVFRWTCDTSSTKPPSPPNNYTHAGTLITLIPSTIAPEFIPSTNSPESTTPSSTSPSPSSTFTAGAFLRDKHNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYJ7</accession>
    <name>A0ABQ8VYJ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mRNA-capping enzyme subunit beta</fullName>
            <ecNumber evidence="8">3.6.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-triphosphate monophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_749509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67004"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
            <dbReference type="EC" id="3.6.1.74"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:67005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the fungal TPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.74" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07470">
        <property type="entry name" value="CYTH-like_mRNA_RTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.10">
        <property type="entry name" value="mRNA triphosphatase Cet1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040343">
        <property type="entry name" value="Cet1/Ctl1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004206">
        <property type="entry name" value="mRNA_triPase_Cet1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037009">
        <property type="entry name" value="mRNA_triPase_Cet1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118:SF1">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE CTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02940">
        <property type="entry name" value="mRNA_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="4 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA triphosphatase Cet1-like" evidence="9">
        <location>
            <begin position="18"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="31115" checksum="76F242E1B04347F1" modified="2025-10-08" version="1">MSSLPPLSLSILGVEPLDEFIKEIADFIHHMIISRPDLPGNVEVEAKIGLLRERGGGRLSLPVLVETILTPDSIDCRFESNMTAAQHKHFNTLLNELKISSSQPGYASSSPLDYHHLRLVDSFYPSETNDREKIRVTRDEKSGAVIECMRKIRLGDLNIYSPKRLADWRVSVNLEVPCSHPVGSSTHQRKKDRMSYSHEEFNIDLTQVTSTNQSGTPEILHELELEIARPALLLLTASKRGDMNAPENERNAFDELIRAFVNNARILARNASDSWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ17</accession>
    <name>A0ABQ8VZ17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">rRNA-processing arch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_805260</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13154">
        <property type="entry name" value="KOW_Mtr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF7">
        <property type="entry name" value="EXOSOME RNA HELICASE MTR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="148"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="413"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1066" mass="120658" checksum="6BF25436537A5D26" modified="2025-10-08" version="1">MDSTDFFSFLNGAPAESEKNDMDEEMEEVDPLETLPQKRKATESFSKLPDDSSSSKKAKMEATPATESISNPVVLDDFETEAKREVAASAGLTGGVEAGSRLELRHQVRHQVAVPPGYPYIPISQHVPPVKPDREYKFELDPFQKVSVHAIQRNESVLVSAHTSAGKTVVAEYAIAHCLARKQRVIYTSPIKALSNQKYREMLAEFGDVGLMTGDVTINPSATCLVMTTEILRSMLYRGSEIMREVAWVVFDEIHYMRDKERGVVWEETIILLPHTVRYVFLSATIPNAMQFAEWICKSHEQPCHVVYTDFRPTPLQHYLFPKGGEGIYLVVNEKGEFREDNFSKAMGEIQERAGEDPADPRSGKGRKGKSKKGGEKKAVSDISRIIKMIMVKNYNPVIVFSFSKRECEANALLMSKFEFNSTDEQDLVTNIFTNAIENLSPDDRNLPQIAQLLPLLRRGIGVHHSGLLPILKEVIEILFQEGLIKVLFATETFSIGLNMPAKTVVFTDTRKYDGREQRSLSSGEYIQMSGRAGRRGLDDRGVVIMMCDEKLEPSVAKEMIKGEADRLDSAFHIGYNMVMNLMKVEGISPEFMLERCFHQFQSSTGIPKLQEELKTEERRKDDISIPDEERVAEYYEYRQQLDLMAADFREVITHPNYALPFLKPGRLVKVKHGNLDFGWGVVINFSKRSPPKNQPMLKVDIPPHEQYIVDVLLNCASGGNVSTKDKINPTPTPGGIQPCPPNQKGSPLVVPVILSTLEGISHLRIYLPKDLRPDLNRETAWKSILEVQRRFPDGVPLLDPVKDMKIKDEKFTALVQKIEAMEDKMYKNPLHTDPRLSELYAMYKNKKELQDSIRSLKKRIQSTHDVLQMEELKCRKRILRRLGFTSATDIVDTKGRVACEISTGDELLLTELIFNGAFNTLAPEHCAALLSCFVFDEKSEKQTKLSEELAAPLRVMQELAKRIAKVSIESKLPLDEEKYIASFKVELMDAVMQWCRGASFSDICQLTDIFEGSIIRVFRRLGELLRQMAMGAKVIGNTELQEKFEKTSEMLERPNSVIFCSSLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0N8</accession>
    <name>A0ABQ8W0N8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADP-ribosylation</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_749292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35214" checksum="C721144F20CC0B5E" modified="2025-10-08" version="1">MAAIVRNVVNWSAQHGSRDRGTTGQVSPSHQVQQRSDLCEVCGKKPKFVERGQKHPYCSRTCAVNTTTSPTTASKTCLLAGCHYDAVFQGFCDPEHAMEAVKMGHVEGCDMCRDQPVSVNARPSRGSSARKLCVGCDRALRGGAQLKELGSKDSKFQEVRKHFIAEWNARNEGLPTVDKVFQVIIPREQLSRYSAYRKNLKNPREIRTYHASLMLCDLGSKGPFLCERKGCGICSVVRSSFKTFAFEEDYEQGRFGPGIYTFVNPKLADTEATTSSTSPYRVMVACDVLVDAGQEVTDDSVFVASSEAINAAYIVMYSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1G2</accession>
    <name>A0ABQ8W1G2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_748338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="231" mass="26644" checksum="E7108F538ECF022B" modified="2025-10-08" version="1">MSSRLASFKGPSTPTSSPVQQRQVSSAPSSPARLVESTYHRKLRTLLQELKSTTETWDDIVLIDGLKSAKSLVDMRTELDNSLARTPNRLPQTRIVGPTLEAMDQRISELDIVLLKLQKQFRKMNTIVESLDALVIEAHKNKGWQWVEKEPLWTTWPLEKFVSRVPEILVPYHRALSGHIALVDILRSHSISFDESRDAILKWAEQPWLEEHGWDAEWEDLCSVEIDRWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZQ92</accession>
    <name>A0A9W8ZQ92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_567473</name>
        <name evidence="13" type="ORF">C8R41DRAFT_765360</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="JANVFS010000069">
        <property type="protein sequence ID" value="KAJ4463592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZQ92"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000007">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="122"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4463592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4492415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="331" mass="38084" checksum="1ABF96542509168A" modified="2023-11-08" version="1">MADSATEIDLDSVIDRLLEVRGNRPGKPVQLQEYEIKYLCTKAREIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLQSMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDITGWSENDRGVSFTFGPDVVSRFLQKHDMDLICRAHQVVEDGYEFFAKRHLVTLFSAPNYCGEFDNAGAMMSVDETLLCSFQILKPAEKKAKYPYGGMNMGRPVTPPRKQKKKDNKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZZ94</accession>
    <name>A0A9W8ZZ94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting 55</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8J55DRAFT_537830</name>
        <name evidence="8" type="ORF">C8R41DRAFT_897426</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OB-RGRP/VPS55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000035">
        <property type="protein sequence ID" value="KAJ4469400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZZ94"/>
    <dbReference type="OrthoDB" id="14246at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034424">
        <property type="term" value="C:Vps55/Vps68 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007262">
        <property type="entry name" value="Vps55/LEPROT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050">
        <property type="entry name" value="LEPTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12050:SF0">
        <property type="entry name" value="RH04491P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04133">
        <property type="entry name" value="Vps55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4469400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="130" mass="13746" checksum="C721E14825DD0873" modified="2023-11-08" version="1">MAAGLKTVILLSFVLAVGFLLIILSCALWHNWLPLLVAITFVIAPLPNALFSHCGADDFSGSYESTGAVDLGRFLTSLIVVTGFAFPIILAHSGVINTSACVMSIMGGGLVYGTILAYSQAFKQDESEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A5F7</accession>
    <name>A0A9W9A5F7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Actin-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_433759</name>
        <name evidence="10" type="ORF">C8R41DRAFT_835860</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000025">
        <property type="protein sequence ID" value="KAJ4473312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A5F7"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000148">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000005">
        <property type="entry name" value="Actin-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4473312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4489088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="391" mass="44384" checksum="66333AB5B9280F78" modified="2023-11-08" version="1">MDPGIPLVVDNGTGFVKVGYAGSNFPEHVFPSIVGRPILRAEERVGTAVIKDIMVGDEAAQNRNYLQVTQPMEHGIIKNWEDMKHLWDYTFDEKLKVDPRGRKVLLTEPPMNPKANRQRMCEVMFEEYGLGGVYVAIQAVLTLYAQGLTTGVVVDSGDGVTHIVPVYDGFALPHLTRRLDIAGRDVTRYLIKLLLMRGYAFNRTADFETVREIKEKLCYVSYDLDLDTRLSEETTVLVESYQLPDGRTIKVGSERFEAPECMFQPHLVDVEQPGVAEMLFQTIQNAAVDIRAELYKHVVLSGGSSMYPGLPSRLEKEMKQLYLTRVLNGDPSRLNKFKIRIEDPPRRKHMVFLGGAVLADIMKGREEFWISREEWFEQGVRSLDKLGRGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVU0</accession>
    <name>A0ABQ8UVU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_784539</name>
        <name evidence="9" type="ORF">C8R41DRAFT_897949</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000183">
        <property type="protein sequence ID" value="KAJ4463272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="7">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4463272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4469612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="11955" checksum="25447C6B6DD717B4" modified="2025-10-08" version="1">MAREAILREMSGVFGIYKIQVDRRHLELIADYMTFERGYKPFNRKGISTNSSPLLKASYETTAAFLSDATLYGDFDDLTTPSGNIVLGRPNQTGTGVFNVRMPSEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX49</accession>
    <name>A0ABQ8UX49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_926944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000140">
        <property type="protein sequence ID" value="KAJ4464476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053042">
        <property type="entry name" value="Mito_GTP/GDP_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974">
        <property type="entry name" value="MITOCHONDRIAL GTP/GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974:SF1">
        <property type="entry name" value="MITOCHONDRIAL GTP_GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="211"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4464476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="32106" checksum="8D768E09234858F4" modified="2025-10-08" version="1">MSPPIGKGKDSGTARVLGSGTSGIAELLIFHPVDTVAKRLMSNKAKVSLATLNPILFRDFATASIGKKFFSLFPGLGYAAGYKVAQRVYKFGGQPYFNDLINQHFRDQFTGAFGERKGKLMMQAAAGSLTGIGEVVLLPLDVLKIKRQVNPEAFRGRGIIRIIAEEKSALYRGWGWTMARNAPGSFALFGASAATKDYVLGVTDYSKATWTQNFIASIAGAVASITVAAPLDTVKTRIQNANFENKVNGAVVIKDLIKNEGVTAFFKGLTPKIIVVGPKLVFSYTLAQSLIPLFGRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXB9</accession>
    <name>A0ABQ8UXB9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYC1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_859516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000136">
        <property type="protein sequence ID" value="KAJ4464699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="1">
        <location>
            <begin position="205"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="446" mass="50720" checksum="95E15E91025081A8" modified="2025-10-08" version="1">MDPSTLSLFAATPQQIEASSRRTGASAWGNGMTLDQYVQRDLDLQKSECGRDGKLMIWVLAPRDDSETLDFLCSCETFLRTGLTARRNPSSPSDPEPLIEQVECYGVASVFTPPPNRGKGYARLMMSLLHWILAGNNLSPNIRFPSDIWGPQPVPPPGMGNAIFSALSTDVGTFYESCNPDNAARTKKNGWIIRGTRTARWNPRVDVPVTSAITSTTGNWRWLTHEEINQVCTQDAERMRADLRARWFDVSSVSSSKTKILFTFLPSGGVEAFQRERLQYFWEKENIVHWGVALSVPRSDLTNDFTNELGTVQAFVAWTLELRPPAPRTLVVTRLHVPSPDYIPEILRRIWEYSIQHDIQVVEIWNFPSELREVGYRSAERWFVPFGGEEGEFEFERALHLPAFKWYGYGPQRMTDAADAVANDSTSEKVDESEIEWMFNEKFCWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXK6</accession>
    <name>A0ABQ8UXK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_859024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974:SF2">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="297"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="650" mass="70515" checksum="1B05F70807F5B09E" modified="2025-10-08" version="1">MSTSTLSQIRSSASYHLSLLQTLESLQYAPSALNQQSKYLRDLQAELASVKKEVKQLGEKTKKERKEHEELRDSTTRRLAARLKGKSGLEKFEAKKEKEEREYVVALENEMRERGKQTMLENMIEEARKVKSDLEEKSNRLELTKKELSNLYHQVFDGPTLEFPRDDVLERELASAQATYDRVQAVLNSHSQAVNLLGQADKMLGMSLKKMDEALGYSTWDIYGGGSISDMMERDALTNSAVYAAKAEMLLNQARSTSGDVQSIGPLRVHDISLFGDVFFDNVFSDIRAHHKIQSNRDELAAAHKRLKGQLRAARQRTQLAGADVVEASEVLTECNKELERYRREVFLRSSGGESLDPAISTGLQHGQGGGDDVDDLPAPPPSYGETSNTTHISSDTLVARSDNSQLFGPTNASSRTSVLASNVNLPPSGSPPGFTRYAPPPGPPPSGRPPQRHGRMLSSPSASTLPTGRTQSMRMPEPSFPSVSPPISSSVSSVPSPNSPYAPRPRNGPVSVLPPSHRRSRSSVSAHSPTSGLNAGSSSTPSTPDLIDASVHRRSRSSVSTSRSTANQHERSLSSPTLESESRQGSPMLTPPRAPLPPSSVLTDSSTTVGQGVAGGGDSSNLPSRSVSSDTSIPAHWGNRNPFAAMMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYX3</accession>
    <name>A0ABQ8UYX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000157">
        <property type="protein sequence ID" value="KAJ4463619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="24472" checksum="D4F9F3248F7CB2F6" modified="2025-10-08" version="1">MSSTPARPLSRTSSPLLPTLTALGEVPSPAPESDGEVEMDQLAFTIESPSRPQLQLFETVFNTGRPFVASSGGGSFPLFQLRKVSGQILGKVLRYRYFARCCSQDIAYSRRFLELHGTPSHQSTWGIPLSTWRQYNAALQARTSSTSTLLELNMLDEQDTAEADQQKLREFLTLQQGEAVVAAKRKRNRSPLPVAGSSSKKSSVQTPDVVEIVEGNVEVGKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V034</accession>
    <name>A0ABQ8V034_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MADS-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_715943</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000133">
        <property type="protein sequence ID" value="KAJ4464840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945">
        <property type="entry name" value="MADS BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945:SF534">
        <property type="entry name" value="MYOCYTE-SPECIFIC ENHANCER FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4464840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="92" mass="10711" checksum="5DB28D148CDA52F9" modified="2025-10-08" version="1" fragment="single">MGRRKIEIQPITHERNRSVTFLKRKHGLFKKAYELGVLCSVDVAVIIFVEEKPGHNFKKLYQYCSCDVQDIVQRHIRHDGEKDTRGPIDFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V096</accession>
    <name>A0ABQ8V096_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000149">
        <property type="protein sequence ID" value="KAJ4463939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="126" mass="14178" checksum="DDB59C71AF9CC6DF" modified="2025-10-08" version="1">MVTRNTALYSYIKEYKIFTGGGSDADLQILTPDSDSWHEQRILLARKGGKALGTLTVKKYCLWVSIGWYDLFDNWFSKSAKVDCVVVCDSAVELSPIQQPKDDSEPEELIPWSPTPKCALHPNNEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0I3</accession>
    <name>A0ABQ8V0I3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="21023" checksum="C102E797E5359E87" modified="2025-10-08" version="1">MPNWHTSAYPVFVSTGSPPEILSEPTKGLFALVQNLIQQLQDPSPVLKEKSTIILPQGLFANLTVPFAAVLLEYPVAYCPSETVVSPFLSSATLDIYEVRLTLPDQGDVTSGRRKAWPSVNNEERHYRSVLKFSCPSHLGHSCPKLNPQSIQESLQSFFDSRIANSLLLMLSTHAISVHHTIESLDRVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0I5</accession>
    <name>A0ABQ8V0I5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_898123</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="497"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4468058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="652" mass="72668" checksum="396CD1754D43BB31" modified="2025-10-08" version="1">MTETDTSVLGKRVRNNQEELKNDHQVASNMSATFDDNDDDDLGPMPMPAGAEGVSKKKRKVLAHEKLYLDHLPHTEQYYKSFMHRDTINFCLVTKTDFLITTSVDGQLKLWKKQDTGIEFVKHYRAHLGPITGVSASTDGQMLATVSDDGNAKVFDVVNFDMINIIKLGFTPHACCWVHKSGQGQGLLAVSDASCGTIRLYDGRGGDEPLETIENIHRFPVHIITYSDKFNTVISADEGGFVEYWQPVEPFGQLENIPGMWSYKSETDLYEFKKSKSTPTCITLSPNSSSFVTFSLPDRQIRIFSFLSGKLTRKYDESLTAIQEMQQAGTAVYKVEDMEFGRRLAAERELELPGPDGRIPGRWSNVVWDESGSFVVYGSLLGIKVVNTVTNRVSRLLGKDESVRFLNLSLYQGGPSKRTAATAAMTASANPLLAERQSRDPSLFCTGYKRQRFYIFNRSEPEDNKSGDRDVFNERPTREEQSIATSAPVGKSGPSPLANTATIHTTLGDIHMRLYPTQAPKAVENFVGHARSSYFEGIIFHRVIPKFMIQTGDPLGDGTGGTSIWGREFEDEFSDDLKHDRPYTVSMANAGPGTNGSQFFITTTATPWLDKKHTIFGRVLSGLEVVHAIENVKTNKADKPYEDIKIINVDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0S6</accession>
    <name>A0ABQ8V0S6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAPP complex subunit trs33</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_854363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="249" mass="27139" checksum="1AB6F59D99B22E84" modified="2025-10-08" version="1">MSSRNSLPVPSSSSSVPPHLAALATFSDPPTRHVDGAMMDYFLIETVNALRESSKIALTREREREKEMIEAGLIPPPALPVKETKDSAVSARDSTGSLASTKGGKVAAAGPVDEEEEALKVRLETIGIHVGSNFSERLCRDRALFTETLDAIKFICKDIWAACWDKQVDNLRTNHRGVYVLQDNSFKTISRLSSWQGRPDAVRKAKVYVSMPAGIIKGALARLGYNATVSPEVTNLPQCTFQVKLPKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0T1</accession>
    <name>A0ABQ8V0T1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_854373</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22061">
        <property type="entry name" value="CSN7_HB_subdom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4468508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="32143" checksum="2217CC41DAE73D97" modified="2025-10-08" version="1">MDLGSNFAAKLEPYLLMGKSMKGAAAAKLIQEATSAPGVFVFGELFELPGIRDLEKNEQHSKSYKLLQLFAYKTYWDYLENKDQLPALNEAQTIKLKHLSIVSMATEKRILPYPQLMSSLAMSTIRDLEDLIIDAIYLDILRGKLDQKESQLEVEYTMGRDLEPGKVETMLNALRDWALTTSAVLATLDSQISTISAQTAFDQKRKEDYEAHVQQIIKEVNDKKESNSSYPSSSGSRRPQGQNTTGSGDRMDVDEPEVQGLVSSGSKGKNRKAPQAETKPSRKRNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V153</accession>
    <name>A0ABQ8V153_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_778427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="184"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="361" mass="41095" checksum="78448E8B97FBDD2F" modified="2025-10-08" version="1">MTPKTSLHNAQLSLPIINITPYFLQPSPEVEIQRATVSAAVHAACRDFGFFYLDISAISDPNEPEELTELARRFFHSSQEDKDRLALSNQDYARGYARLKENVTNGKADNHEGIDFYRPVDKPDKTKPLRGENQWPTVPLFRERYETWVEKMKMLGLVVMEAMAVGLGMTPDEWQELRTEVDDSFWVMRAIGYPPLPNDYDGFSCGAHKDYGCLTFLYADPTLGALQVFLRRSEVGPDLSGLPVEQGDEEGVWINADPKPGCVVCNIGEREIWSNGLYNSTLHRVVHRGINYRIPFFFEPNFDALIKPLEAALRIQEKEKENTTLPVNARKVKEYKPMVYGEFLLTKVSNNFANGKGKYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1H7</accession>
    <name>A0ABQ8V1H7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_853451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="86"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="260"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4469187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="460" mass="50689" checksum="ED4C523B0A3A3DF2" modified="2025-10-08" version="1">MAEALKALVKIISTETDALLSAYATHEVKFPSIDETSTTSSKKNTDFDVDPTIVRMRQLIVAAAAQLIATVQPPGEFLQDAGPAMFKSATLGFVVDVDVPEILMEAGPMGLHVKDLAIATGVDDSHLARVLRYLATRHIFREVEPNVFAHNRNSTLLSKGKSVKEIKEDPLGRFDNSPFTAFLHMASDELLASSVHLSAWLRNPGQAPAALNMGCKTSKKLWDWYEEPNNEARLRRFTVGMKANAYPSRIFTNGIHGDALKADDVVVDVGGSLGTVTLVLKEAFPKLNYVVQDIDKTITASEDYWREHSPEAFESGQVKLQAHNFFEPQPVKNAAVYFLRNVLHDWPDEEACEILSNIRDAAGPNSKLIVFESLARYTCEDSSRTNFSLPEAPYPLLKNLGVAGEGYLTALDLGMLALFNGKERTLAEFEELGIKTAWRLESVKPSSLYTLVFSPITGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2D9</accession>
    <name>A0ABQ8V2D9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_853259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="69" mass="7953" checksum="3AFB0F26B45FA604" modified="2025-10-08" version="1">MAFLAFTDMSYQVLIPLIHTTSIPVGRLGLSVSRFDPRASQTALLIYSFFLLHFSLLWILQRMSEKLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V368</accession>
    <name>A0ABQ8V368_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_926279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33276" checksum="29D26084E2BA951C" modified="2025-10-08" version="1">MDTLPIEILTDVLGIVLQDAAAKPTNILCTSSQFQYIAQRILHRDLCFYSSSQLSQFASLLSKGTLSLVCEPQTLMLDIAGGASSGIFEGLYAVLTEILSNARCKKDENGRANARNFMWTGPDPPHHFSTAIVSPAVFPLFTALSTYSRLTHLHLTNIAFPNPIISPDAHWTGIPCLPSLRSFHLGQATFLTTEHIADFVLRCTGQLQNSSCNLKSSKVVFEHIRLVDVYEESIWGPRLKLPRILSACTTMLEESQSSNEMLSSTISDLIDFISVDAKTERIVGGDRVIPEVLTILATTHAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3I1</accession>
    <name>A0ABQ8V3I1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_587921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF195">
        <property type="entry name" value="ACID PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046103756" evidence="2">
        <location>
            <begin position="23"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="484" mass="53502" checksum="2EE41FEC14CAEF18" modified="2025-10-08" version="1">MILSNGLMFASLALDFVNFASATDIVHYPPKLTNLNNLTFVLNGIGTPGIFNSSITPDFEYGMYNWCNMPHVRAREYQTPSSAYTLKYIEIIQRHHERTPYASNTFFKEDIRWDCTGEGPVYYGKGTVGVTDDPTVIQWSAYTNSQNPFTNSVGPGFVGSNCAFLQITTGGLNDSYTHGADLRAVYTERLNLSTKADPNTFKIRVTSNPITSQVSGGLLKGLFPDSSDVAALIQADAFDSLTASYSCPAAKSIFTAYTTDSSNWTEHLVNAAGIYEELDEVSGIAADDTAGWHTSFDHYYDNLSAKQCDSKPLPCSVNDTFLCVTQPLADTVFRLGNYEYSYYYRDAYNSTLFSALSYGAWVLELVGHLKEQVEGTSDVKYFHNVAHDGSLSPLLGILQISEMVWPGMGSEIVFELYEKNSSYNSKSISNFFLRVLWGGQPMQTSLPFGTNSSGLLDMIPVEEFFEYVHNTIGTGPELFAACQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V411</accession>
    <name>A0ABQ8V411_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="195" mass="22096" checksum="F18F533A474EC150" modified="2025-10-08" version="1">MPNEESVCNLPCKLWWLIFKHMSPVDLAVFSRCSKMFHELGTCFKQEMYTVERALGKFLSDVEMGDYQDLQAETGLLVAGPGVLGFFNHNDDLRDYDTFCDLQQCGIVGTWYISHGFEFEPSGIQLCYFANDLARTLDVQRSQNHVLAISIDEDIRDYVHDNVVAVWTFKRGCGMVRLLATDGIPLKGLLSVHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4T2</accession>
    <name>A0ABQ8V4T2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="444" mass="48919" checksum="BA0E7B07F39330DC" modified="2025-10-08" version="1">MSKIVSHDPRDSSMCVSISSLGLFQSFRDSKATHGMSSYSYLPNSVAHPLFADRTRPNGVYDRLAKSFMDMGPAALANAEVNEHFFRHNFGESWSTNYSYWDCNSLQFSANVFSKVVGQAFGTYAGAQGNHYAGRDPKNPIKITDSTKVKCTFVLGCPTNAPASIQNLFYNQICTLDGMRDVDRIEEQVDVKEIVKSLRSGGEADALVLTGEPLYTVMKKENGKKQSESQRKTVVHPRSKLAKRTVDGDLKLVDVEVTLDLPDSIVNPVVGPAIPKQHEIYLGAEYDHRLMPDFGGPVFTLDKAKLVQPNWQNVKNDFITPWMNYDQLRPGVLVVTNIGIRVYVLTPKYGSGNIKKIYHATINSMKVVAESPIPVTPPSAISRQGKSLKATVEKEVSAAASALDAIVWRETTSGREPGESVCAVDVPTERDGAVADGKRKKQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4X3</accession>
    <name>A0ABQ8V4X3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fido domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="240"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="402" mass="45754" checksum="0C1CFFB3ABB81E4C" modified="2025-10-08" version="1">MLQNIPDALTTEDATRLRDSFRVSPRDQVKCATSARLWEELLERYRLPFLLLRVADLRFITRGPGSQMTSLHLYVELGKMIQDESYDVWLSQLLASVTEQTNNMLSAYKSAQNITPNQHWRRRTSEDPFPYCRMPKAFIDELRQNWKKLSIMDSSVLSKFINLHCLETNVIEGTVQFDPTATTTLVQVGFLNEATPEQITDSNIISGTVRQSRDALLILRDTHKAVDEIFELVKTSPVVITPEWVCCLHKKMMASSRVNVLDVNGNRKLNHITIGATRQLSCVNVAIQTSFQGRPLRVQFCPYDSVDAELATFCKQCTVLLERNDVDPFAAAAWISHVFITIHPFEDGNGRLSRMLASIPLLLQELPPICIGLSEKSNYNGFLNAVRKPHRRIYIPLWSNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5M5</accession>
    <name>A0ABQ8V5M5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phorbol-ester/DAG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_554011</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="4">
        <location>
            <begin position="587"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4474530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2243" mass="251688" checksum="94E1906D5B4D5432" modified="2025-10-08" version="1">MESYQSPNTPLHINTEWLANANSPSTSFSPTGPSGRDVPALRVSTSPTRTSFEKPPPSPRKDNSLKNTSRGNESKKLLAHVLEQIKDRNMPPSVYDALSSAAENSNEKKLGSFIDRAVKRRDAGKDRKAALYADDESEDEDERAFSTDATLELMTRLRELLIISASQGWRIFDDGISQDPYMQRTSSSGRFSSPFRRSLQPGGKRSRSPSPDPKARDTTSTGLLTQCISAIASVVSEDCRFQIASPSPSRPPYALQAVTLEVAQFLLHTYRRASEIVSQIVFALIPAFSTFPREMHARLLAFFEECVTRNALEELSLIQGVRGIKSAQGPQQQIEEQNETVVSIRVDEAFDDPMSPGTSEWTPWTRIGAQLVSLRSTNSPFQSPSTYDYASFFSPLLAAILENIDFVRSRVEVLQRLYRLLDAIITLKLDAHLDVLEIIAYHTPNARRSATCLLTTFWPKAVGHVIVSKSLVLRKFLDLQAGTKLPAYETSYHVHQFTPWFFLDLGQSTLDKPECDACTNPVQGFGLFCPFCICTVHFNCYHYPEGNVSINYTSNTDANVKQVAMYRLSPILDRRTVAGAGTVQTQYHNFRLVNIFTLCLCMLCQKPLWGSHTQGLQCTTCHRFSHSACVSASHVPPCGSIQNDWSCVMITPSALVQSCVDFYQNLFSLTEHNVKNGGYEDVSIIYSSLSTQLQIINNGLELGSIVLSEGNSSRSQTQEVPAFRLHDLLAWCEHYLSAETLPVSPVISEYLEENHVFRRNLNMMFEWSNLVYIASAIKTTFTPRGPLTPSSEMLSVSALQESSLDPEENNSPFEVVSLAHMRDVLGYEFNVHLDAAAKLLLSHMHHVGLFDRIDLEPNLFLSEAQDTYCSFPLPIGLDESPDVEALFASVEACLSDLDLSVNEVGLLLLCRRLWPSGMASDYALTRLARSIISWVLSEDKDLATILRDYLARQRALPGVRSASDPLPWPSVPNGRPAPSSSVNNGGDYVASRKALVSRYAIPWLLALHHQNSENYCNILYDICAELVDDETDLPTDLFSEVPDHDVKAHAAQYHDKVLRSLTRLLHNSLTFTVSEKLFMRWLSSLSNSGIISYPIPSLVRLFQRDHQDHRYSIMDKPLPISEGSEFDPWHHILASAETFNGLTNSICWLSVVASSGVDVSVATYFHFANLVESFKLPVSSSLVFMNAIFKSVWLRHAGRQQMQKIITDLHFRLDSEIVQSLKKKEMCHDAVLFIKQSLVTCLLLYGCDREKLQSTELVTKDDIKDLPHRRILGRESQLLDPIVVDTVLMNALASYVAANVDEVTCIIAKFLNIFITESPTLESHEVDNFILRNGQMMTNCAFKFYDIQSHDISTLRTSFLLRVAVVDTQPLQELLEEWFQPHEDWKLRLSALVKLFRIILDVTSPAFTVEGRQWRSTITEVFYYFFSTLWADEKEELRLAADTFSSNLLPAHFEQISLCWSELLAKSPIADRVKLVSFLIQLRPHFPSWHMVSWESIVEIIAEDQYDQDAGNDGPLSAHLSLYGLSSKEDPVPERFSADSELTSLRISILLLSLDMIAEGIRIDYNDLLRIKQHVAQTLGFADVHAIPAANGHSFFVEFGDCKSIPSVAYPCISHLFVLLDAHHPLLITDAELQGFVNDRAWPLLVGSPYVDILLRLFDSEIHELPGLTLKGLLESLGVIIYKHNIENVYLRHLQPQLKRAVSRVQEIMLKDIDYECRQVALSVLQSYIKKYQGSLRSFVHFAIEQVAKLVVSQSHLNQDPLVLQAKAFIESMLTAYCNNGIFIGLIRRQLDRSLFVVLKQVLDTNAKESGSQLLLDTILYDTFRRAVETDQNSFQVMLNNLQTFVEVVHHQNYSAETMTFVGQSLTYLTRRISEWSPEVVNPAPLLLIAALLIQHNKAQSRDFLSYTDTVLRAVLTRMLVDGATLSRLVQVTATLYRKGPSVNGEPSNNIIPVIFEILNEGLRVKARVLSGTINSMLETVMSTNINGSTTPALSHSNLFVGLALPGIHFLYNYSWTDHRTDNDFQASLTVAKVLLRVSSKDPDILMKFVDVSTEKTGPQNTSIRAWNILLLAVLQDSSGESINMIFSHLATFSLVHHAALRPYTTRPGAQIPESAITDINHAYIAIKVWLIVAQIKAARDGAGSTDALIVWNELYSVFESLIHFFEAEFRAGLSSTLAMLTWSTVADLFLFLRHLPSPVVLHTSSQISLLERLKPLGRGEAHTGKVGKHCFLIREDKLSSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6H6</accession>
    <name>A0ABQ8V6H6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_773381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF55">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="104"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4476787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="54341" checksum="D82AD4BF132AADE3" modified="2025-10-08" version="1">MSSSIYSSSRPTTSSLSDSPHASSRHLSGRLREAFAAPSSRPLTIHSALAPAKSKRDRPKSTMLTTPPNKPWLSSRDPYARIAYSLTYGMIFVGVVVSAVKCFLDYRNVPMITGNLCMVLNEDFSSEDGVFGDNGTFFREVDMSGFGNGEFEMTTASENNSFVENGHLYILPTLTSDSIPMADILDGHIYNISGCTYNITQGLSYTDSSSTAATNVNETAIGSNTFDAEAYYKACSAVSNATAGTIINPVQSARLSTRKTASMKFGRVDVVAKIPTGDWMWPAIWMLPVDDAYGAWPLSGEIDIMEARGNGPSYPKQGTDYVRGSLNWGPLTWLNEVWRTYGWWQMKRGSYDKGFHTYSLEWTEKFIRIYVDSRLHHMLELNINEAFWDRGDFPAVVQNGSEVVALENPWVNGTNAAPFDQRFYLILDVGIGGTNGWFPDGPEKPWLDGSLTAMRDFLNAQDQWYPTWPTNPDQRAFVIDSVQMYEQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6P5</accession>
    <name>A0ABQ8V6P5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="235" mass="27056" checksum="2E14021B86B08626" modified="2025-10-08" version="1">MFTLSRRDPHFFPYPLIPSTFATTTVFVDYLTTPLVKRFQGSMLPRIVTSPFFVLPCLWVATLAVFALPMPTGGKDAAVVFGPQLPMIVDLHIFIAQMNTLEEHLLMGIGDTIIHANVSDESQRITNTTLIPRKFTVHLETLKKVYHTVPIGEARFKDEQDEQDVIKEMLQLKLPPFSHRGTCRDYISQVLQELKVRGYIIDPGVLRRYRKIYNERYEKVFKDYYTEKGIESGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7R1</accession>
    <name>A0ABQ8V7R1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="127" mass="14746" checksum="ED3F87CBC308B8D2" modified="2025-10-08" version="1">MASREQQNYEDTKNFLYSHRSYKIANLGYTCLELKDPWSVDMTLNRGRDSQYQRAAILAQDAATKAHFYLMAVNAPTHHLVYGQMRFLVICDVRELEMTLQRVDFPIDQNALDLFSPVIRTGQNIMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9L5</accession>
    <name>A0ABQ8V9L5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arginyl-tRNA--protein transferase 1</fullName>
            <shortName evidence="5">Arginyltransferase 1</shortName>
            <shortName evidence="5">R-transferase 1</shortName>
            <ecNumber evidence="5">2.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginine-tRNA--protein transferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_896679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = an N-terminal L-arginyl-L-aminoacyl-[protein] + tRNA(Arg) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10638"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83562"/>
            <dbReference type="EC" id="2.3.2.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the R-transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.8" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017137">
        <property type="entry name" value="Arg-tRNA-P_Trfase_1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037207">
        <property type="entry name" value="ATE1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="N-end aminoacyl transferase N-terminal" evidence="6">
        <location>
            <begin position="14"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="N-end rule aminoacyl transferase C-terminal" evidence="7">
        <location>
            <begin position="156"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR037207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4482658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="376" mass="43215" checksum="FB6D3D651E3CDCEE" modified="2025-10-08" version="1">MILSVGQPIGRHASSCGYCSPSGERSKADSSHTAASLVALQLSSEVYQMMLNRGWRRSGRFCYKPHLRSSCCPLYTIKLDVLCFESSKHHKKLVNRWNTFIQRGGNAGNRERQKGKDNAKFNLRASIHASEFHSDQNQQFAHRFEMTLEPSSYTDEKYELFKKYQTEIHYDSTSPGGFRNFLVATPLHQEPIQYSSPPISDLPTHYGSYHWCYRLDGKLIAISVIDILPECVSSVYFMYDKDYEAYSLGKLSALKENVLAQELHAAGAPSLKYLYLGYYVHSCQKMRYKGEYQPSFLCDPETFEWYPFADCTALLAEHRYACFSRPEVQDFKESHPQEPEQDTLERVFVISEVDGPQVSVIPANVNHLRIDIFVHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Q2</accession>
    <name>A0ABQ8V9Q2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_770482</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4482625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="383" mass="42899" checksum="F1AF00A2A9DFFE76" modified="2025-10-08" version="1">MPLFDVPGWSMPADPVSEAGSRKRKRPISDAGSETQSRIHSAEINLEKLVKKLTGNRDVGDARTNAAPHSKPKPRRKTKKSQPTAEVDKESISLPMPLMKASDRATKKTKRSHDSRPPDSEERPERSSKDLDSSSGLTGMQKNMKQKLEGARFRMLNQTLYESKSEDAQRMMQEDPTVYTEYHSGFRQQVLSWPTNPADHYVETLSSYHVNTIVADLGCGDAAIARALIPKGISVLSFDLVSHSPYVVEADICGTLPLPGSEGTEGSLSEGEAHIVDIVVFSLSLMSTNWPKSIREAWRILKPNGELKIAEVTSRFRNLENFVSLVSSIGFKLKSKDERNSHFTLFEFRKVPRGFKTSKEWDIIFSKADTLKPCEYKRRCASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAI0</accession>
    <name>A0ABQ8VAI0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_839697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06293">
        <property type="entry name" value="Kdo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="26238" checksum="F074A301ECA070C0" modified="2025-10-08" version="1">MTALRNLFRSLLKVYKKPNDYAVDPDQVSFPYPRSYQRFGTTVRFTYIKRVSQIRLVFTARTEGDQDIIIKFGYGPYGVEAHQAAAESGFAPALLSHSNLAGGWWMVVMENLESDFQPCDDFDILEPPCKDVITECVSKFHTMGFVHGDLRDTNVFVRRKQDRWECQLIDYDWAGREGEVVYPIGVYSTHSVWRPELHLDGQSITSEHDNLTVNEFLRRRTKIIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAQ5</accession>
    <name>A0ABQ8VAQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Argonaute-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_839383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="1">
        <location>
            <begin position="237"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="522"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="888" mass="98413" checksum="971B47B1B7ED9C5C" modified="2025-10-08" version="1">MPPRVSNAVNVPSTANHVTTIGVKRTAFGSSGRPLPIFVNVFETTLPQNIIFHYDIIHPADKVLPARLNMDLIRALQTRIAPDVFTPLGVYDGRKNFFSARKLPLGPDDLREFDVTLESADEAPKGKGPKVYKIRFNLVAQINPEVLRRYIDGKQSQDNAVLTAITALNVVIRMEPSQKFPFNVRSFFTDQEKKDIGSGLELWRGYFQSVRPALKKMHIIIDTSTATMYKAGRLINLCLDFFNKSDAKILAPSNGFPDRERLRLQRFIAGIRVLTPTPDGRKIARVVKKLSSAGASALSFKLKEGGTMTVAEYFRNVLNRPLQYPNLICVEIGTGALIPLELCEVPPGQIMRKQVPPEKTKMVVEFATKKPQDRLKSIEAGLQVLSYGQSDYVRNFGITIPQTRAMKIQARVLNPPALKYGPGSRQLTIVPANGQWNMRDKRFFKPVDVLRWVIVVYERKQRFNEQAVAEMSRGLCGSAREVGMKMTPTPFVVWYSGQGDIASQLRASGKLVYDQFKAAPNLIVVVLPEGGNEIYTAVKHFGDITMGVATQCLKSTKCFGAKAQYFANVCLKINVKLGGINAIPDPNSVKALTDPQNPTIVMGADVIHPAPGSQGRPSFTALVASVDSDNAKYVAECGVQTSRQEIIEDLELMAKNTLTMYATYRMGVEKKSIQMASPKRIIFYRDGVSEGQFQQVLDQELVALKKACAALNIKPKITFIVVGKRHHIRFFPTNKADADVSGNCPAGTVVDREIGHPTDLDFYLQSHGGLLGTSRPAHYSVLHDENAFSPDALQSLSFALCHVYARSTRSVSIPAPVYYADIVCSRAKNHYDPQGTIDFSDSATNNDSAQAETTLEAFRKNFKPLNEAQKKLMYFSAVLYCVIDMLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBJ2</accession>
    <name>A0ABQ8VBJ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WIBG Mago-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_841155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039333">
        <property type="entry name" value="PYM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015362">
        <property type="entry name" value="WIBG_mago-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036348">
        <property type="entry name" value="WIBG_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959:SF0">
        <property type="entry name" value="PARTNER OF Y14 AND MAGO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959">
        <property type="entry name" value="PYM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09282">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01273">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101931">
        <property type="entry name" value="Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WIBG Mago-binding" evidence="2">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="165" mass="18131" checksum="455853FB8459807D" modified="2025-10-08" version="1">MSKSSLPPIDPTKTASGIALDPQTLERVIPESRRSDGSVRKQLKIRPGFTPQEDVRRFRGTKQTQADANAPPKGHIIGWIPPSSKEADSSKPLSKSAKKNAKRREKKVSDKKADELVKDNWEDDDDDETIAVAPQKNEAPTKTNGAQSTDAAESLSSKMEKLDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCD8</accession>
    <name>A0ABQ8VCD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_840866</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17953">
        <property type="entry name" value="DEADc_DDX46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="431"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="462"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="664"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="828"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="431"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="41"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="838"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="868"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4482620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1096" mass="121661" checksum="9B9A741A5643DFA4" modified="2025-10-08" version="1">MVRRDRSYSPDSSNKRVRHSHRSSPRSPSPTRRSSQRSSNRKYEDERARDWDRDRERERVRDRDRDRDRDRERDRDRDRDRYRDDRHKEDRRRDHRDDNKRLSPSRERERDRRPASPRKDNPRDSPAPGATPAPATQEDDAIKAKRARLEAWKKQREAQKALGEAKAKAMALAGKSAPPAPNNTNNNNVVLPTKPALAAIKGLPAKPEFAAAGFKGLPVKPDFVSTKQLTMDDSVETKRKLEKLEDMPAVDMTMGGEGEPSVGDLEVDDDDEEANRMDLAIKKAAAASAAMDVVEEDEADPLDAFMSGVKEEVKKVNLEDMKKAVSSNGRLSRRMDQGDDEDDNVVEGPGPDELDTTELNPEDILALAAKKAKKKDLAAVDHSRVKYESFRKEFYVPPPDIAAMTEEEADLLRLELDSIKIRGLDCPKPVVKWSHYGLPANCLDVIKKLNYTAPTSIQAQAIPAIMSGRDVIGVAKTGSGKTIAFLLPLFRHIKDQRPLEQMEGPIAIVMTPTRELAVQIHRECKPFLKVMNLRAVCAYGGSPIKDQIAELKKGAEIIVCTPGRMIDLLTANSGRVTNLKRVTYVVLDEADRMFDMGFEPQVMKIINNVRPDRQTVLFSATFPKQMDSLARKILRKPLEITVGGRSVVAAEIEQIVEVRAEDTKFTRLLEILGQMYNEDPECRTLVFVDRQEAADNLLRELMRKGYLCMSLHGGKDQVDRDSTIADFKAGVVPIVIATSVAARGLDVKQLKLVINYDAPNHMEDYVHRAGRTGRAGNKGTCVTFITPEQDRYSVDIYRALKASNATVPKDLEELANGFLDKLKTGKAQAAGSGFGGKGLDRLDKERDAKEKAERKAYGEPEEEKPAVTEEAAPGGAAANAAADDMTFGNFKVEIKRGPAPDSSKGLLGVAGAAAAARKLAHAKEEEKIQAQMRAAEEAAARAGKDSPAHKQALSVVAKLNAQLRASKLVLQSQLAFEQQGGVVDKKNNPDSTDFHAIIPINDYPQKARWRVTNKETMVQLIDMTGASVTNKGIYYDQGKEPPLDGPPKLHLLVESNEEYRVEQAVREIKRLLIEASAAALQAEMRNPTATGRYSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCN1</accession>
    <name>A0ABQ8VCN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_422306</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02603">
        <property type="entry name" value="HAD_sEH-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611">
        <property type="entry name" value="ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611:SF3">
        <property type="entry name" value="FLAVIN MONONUCLEOTIDE HYDROLASE 1, CHLOROPLATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="513" mass="57905" checksum="341032BB946F7CD8" modified="2025-10-08" version="1">MVALSRPSSSSSSSIRYDTIIFDLGDVLFTWSPSTKTSISPKTLRSILQTTTWFQYEKGDISEDECYTSVALEMALSSEDIRNAFQHARETLVSRPVMVDLIRELRPGRKIYAMSNISAEDFTFLQTKSSDMDLFDHCFTSSSARERKPNIGYFRHVLERTGADPARTIFVDDKLDNVLAARSFGMTGILYDDFENVERTLRNLCFDPTIRGEAFLKQNAGQHLSYTSTGVTIHENFAQLLILEATHDPSLVKYTKYDGPFNFFRGEGELTTSAFPCDADTTSIGITCSDHMSPEKKHEVMDAILALRNADGIPQVYFDSSRPRIDPVVCVNVLTLFYKYGRGKQLKECFEWVESVLRYRAFSEGTRYYEPPEAFLFFLSRLFLVAPDVYKRLGTVFAECCRERIGLKGDALALAMRVVCCNFAGIDASGDLMTLRNMQEIDGGWPDGWFYKYGSNGVLIANRGFTTALAINAIKGAGVRMKRPSSITNLKQAWNDTVVRIPHRFRSTAHDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCQ2</accession>
    <name>A0ABQ8VCQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_402497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="696" mass="76526" checksum="2887A1F882F13F68" modified="2025-10-08" version="1">MSTQYDLVEKPFPPMTSPNSAYSFDFGRDNLSAPTTERWHNSHRSRRSASEHTLTSSPRQSWEVQPFNTAFRASQNIIKNTLRVDVRSHAPHSQSSLTAAPSANENNISFVSPSLSLASSTWWSSSSSSSSPAISTPFTFSSPFVKKEEPDSPQFIIEPLLPSSLVTKRSSSSSPEPCSSPTQAELESQLLLSQALAPPTEVPLRATQACDDMRQMMRSFRLNPFSIFTSNGKDLKSDMSDCSDSDPVVTWCGEIAKPLDEEPLIFEWQLDDYRSGLEGELPQLIVLDDVECSLDITGPEDSLLEATPREDPESPMIFSPSESLLPSEVASRSGFSTPVETEFQCTHVGLPETLPNTISFFPNFGPKQVETKQQRDGSYDSGYESNASVLTNPLPAYDPECLTNSFHGRSLDSGTYNPSFKKPRFSFHTDDNRTISPTSRSYNREIAFHTGYTREPPSHQLANENSLHTVRELGSDGSLNISRHSKALAAPYTVSTMNSGHDLNHKRASYGSMYIPTLLNTDSPNIRVPPSPYPTSYGPFTQSPTPLKFGELSTRMSHPSTTSSDSPTSTLSSSHPAQSPSTQDVMNVNRIWSNAANPQPDPNPSSELTLRQLHRQQQERVRQYHSPALSMLNAAIRPGMAVSSSLPPLCYLGQQQQQLAHLQAPQGRTLLSPLTSDAAHTRLRTSGQAFPALAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD18</accession>
    <name>A0ABQ8VD18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_959784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4481788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9485" checksum="EE16D5F56FDFC073" modified="2025-10-08" version="1" fragment="single">GIRILEKAVQLASVYPGDICVSRPLTTPGQPFSLRMDDFRLSNMMIDPSTGHITGSLDFEGASVAPLWECAYMPRWLQLSGMGRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD30</accession>
    <name>A0ABQ8VD30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047166536" evidence="2">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="11380" checksum="E0A5424BA666D74B" modified="2025-10-08" version="1">MVRITSTVVAACLVACVYASPVVDRKSNNIARLDSELLKGRSFAANGGEPSPEDLSGRAFAGNGKEPSPEDLNRRAFAGNGKEPSPEDLNRREFASDGKEPSSEDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDF6</accession>
    <name>A0ABQ8VDF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="5">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_387882</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02663">
        <property type="entry name" value="Peptidase_C19G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF733">
        <property type="entry name" value="RE52890P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="7">
        <location>
            <begin position="36"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="497"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="538" mass="58644" checksum="0C7022F22A241795" modified="2025-10-08" version="1">MAKSKWIFGNQQNQPATVVVNPAPLPIESSADTRQFGLENFGNTCYANSVLQALYFCAPFRDLLLQSPDSPPLAGGSPSENYNPSPLVPVRRKPERKASTSGTINDGASAQAVIPIPPNPTSLFSALRSLFLHISTHPSDKGTVAPSAFIEQLRRVNELFRSTMHQDAHEFFNYLLNKIVEEIEEDRKVSQHGSGSADDLSNSITTLGSKVPSTMNSANSDPLPDSTLVHKLFEGTLTSETRCLTCETVSSRDESFIDLSIDIEQNSSVTACLRQFSASEMLCQRNKFFCDACCDLQEAEKRMKIKKLPNVLALHLKRFKYQEDSNKYIKLSYRVAFPLQLRLFNTVDDAEDADRLYNLFAIVVHLGNGPHHGHYISIIKTLGTWFVFDDDNVYPIPEKDIPKYYGDSNAGSAYVLYYEAADIDSTSLGLRAPPLPTQTTASIPPSPSLTNPTLPPGLADEGDSSDLSDPPFPVTPAQNSPLLVPIGNLSRPALELKVAGSNGVPPQSPASPAPVSSPANGRGSKAQILSEQLSTLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDX9</accession>
    <name>A0ABQ8VDX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
            <ecNumber evidence="2">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">C8R41DRAFT_921597</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EC" id="2.3.1.86" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03447">
        <property type="entry name" value="FAS_MaoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013565">
        <property type="entry name" value="Fas1/AflB-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041099">
        <property type="entry name" value="FAS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040883">
        <property type="entry name" value="FAS_meander"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08354">
        <property type="entry name" value="Fas1-AflB-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22235">
        <property type="entry name" value="FAS1_thioest_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17951">
        <property type="entry name" value="FAS_meander"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17828">
        <property type="entry name" value="FAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="17" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Carrier" evidence="23">
        <location>
            <begin position="2220"/>
            <end position="2295"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="24">
        <location>
            <begin position="3143"/>
            <end position="3704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="2653"/>
            <end position="2673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAJ4484514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="3937" mass="432241" checksum="1199DCE3D27FD500" modified="2025-10-08" version="1">MATISANDACSSSITMRPIIISLDKIRVSIPVSTKADEWISAEILREEFTHEQSLIDAVGNTAELENQAEASLELAARFLGFIATRVHENSECTAARTALLLNVFKFFTSTYLYSKDIHSLASNYDTEVRKAVLTSYFSAFSVLSERKAADIPRGPQSALFVAAAAGEASIYALFGGQGTNEVYLDELQSLYDIYKPFVASFISTMSEILVPLAEEKQFSSFYTHGLDVSSWLSGVVSRPSISYLASVPISFPLIGLTQLVQYLIVCKVTGLTPGELSDRMTGATGHSQGIVSAVAAAASSSFESFTENAKKAIRWLFFCGFRGQEAFPIVSLEPGLIQDSIDGGEGMPTPMLSITGLSLKELEPHLVQTNNHLADNSQLQVTLHNGPRALVVTGPSRALHGLVVNLRKIRAPSGADQSKIAFSQRKPVFSVRFLVVGVPFHSVYLGEATDKLLSEDLKGEELWKPEELRIPVFNTEDGKDLRVSKTSITRSLCNQIFTSPIHWTEATNFPKSATHALDFGPGGLSGIGPLTARNFDGRGVRVIVIGERGKGDAELYDSTTVQREDNWGEKYAPRLVQSRDGTVHLDTPFSRLLGKPPIMVPGMTPSTVQAGFVSAILDAGYHVELAGGGHYNANALRAKVVEIQGKIPQGAGITLNSIYINPAQFGFQLPLWQEMRKEGFPIEGFCIGAGVPSTEKAAEIIDGLRSSGIKHLGLKPGSVDGIRQVVNIAAANPDFPIIMQWTGGRAGGHHSYEDFHQPMLSTYRSIRKHENIILVGGSGFGAAEDVWPYLTGEWSVAYGVQPMPYDGFLFGSRVMVAKEAHTSSSVKDLIVACAGVEDQQWEGTYTKPSGGVLTVRSELGEPIHKVATRAVKLWKEFDDTVFKLPKEKRSAWLLEHRDEVIEKLNKHFSKPWFGWKKDGSVAELRDMTYEETVLRMVRLMYVAHENRWVDISLRNLTGDWMRRIEERFAGVNGSGTKPSVLQSYNSLNDPLPCVETFFKAYPLASQQLLSADDSGYFLAISQRRGQKPVPFIPVLDASFEVWFKKDSLWAAEDVEAVFDQDPERVCILQGPVAVKHSVIKDEPIRDLLGNINSSLIQKVLQLRYNGDASTIPSIGYLAPPRRASRVPAGVKITTTDEQIVFQFGKSLPTNASWLACLAGSQLNWFGALIGSTSVVQGSSYISNPIRRLFYPRPHEKVVVSLSNGQPTSIVAYGGARSYGLHDPNFKATEIIFNSSTNLIDVTIFEERNKVAVPLTLQFEYKSAMGSAPIHEVVTGRNMRIKAFYWKLWYGDDQSLPELDIHDTFTGPDVTLKAEDIEKFCSVVGNNDESFKSVRTTAISAPMDFAIVAGWQAIIKSIFPGSIDGDLLKLVHLSNSFRMMKGARPFQAGDICRSEAKIVSVVNSGPGKVVKVKGHVYRDAKPVVEVVSAFLYRGVFTDYENTFETTEEPDYVVTLATDADVSVLQSKEWFDWEDDTRPLSPGIPLIFRVQSEVSFMDRTSYRELSVSGEILVRDQLKNLQKVGSVEFQADDAYGNPVVAYLRRHGIAQGLTVPLANEGYQLTTTEGSTSFFSPLTNEPYSGISGDFNPIHINPYFSCYAGLPGTITHGLWSSAATRKYVENVVAKGHPDRVLSYDVSFVGMVLPGEQLTVNLRHTGMRDGNIVVKIETVNVLGEKVLEGSAEVSQPTTAYVFTGQGSQEPGMGMDLYNSSPAARAVWDGADEHLRAVYGFSILEIVKENPKEKTVHFGGIKGQAIRQRYMDMSYDTTDKDGHIKTLPLFADIDIRTPKYTFSHPNGLLFATQFAQIALVVTEKAAFEDMRSKGFVQTDCAFAGHSLGEYSALASIADVLAISALVDVVFYRGITMQRAVERDSENRSNYAMCAVNPSRISKSFSDAALREVVDTISVGTGSLLEIVNYNVEGQQYVCAGELVALQTMTNVLNYLKLQKIDIAKLTETFSVEKVKEMLGDIVKECHGRALDQKKAEGHILLERGFATIPLPGIDVPFHSRYLWAGVMPFRTYLSKKIDPTHINPDVLIGKYIPNLIAQPFDVSRAYAQIIYDQTSSPRLDKVLKNWDEENWGSAAQRQNLTYIILVELLAYQFASPVRWIQTQDLLFSHFNFERLIELGPSPTLTGMATRTLKAKYELQDDCVSLKREILCHAKHSKEIYYLFEDEAVAESVPVEVTESVAAPVTATAATTVPLPVAAPTGPAVSIEDVPVKSSDILLAIVAQKLKKQISDISTSKSIKDLVGGKSTLQNEILGDLQQEFSSAPEKGEELPLDELGPALGSGHSGALGKYTTGLVSRLVGGKLPGGFNSSAVKAHLSKTWGLGPQRADGVLLLGTTMEPAKRLGSEAEAKTWLDGVVSAYAQRSGISLASPGAGGGGGGGGSGGAVINSEEFTKFQAEQERFAAQHIELYMRYLKRDSRSGEIAFDAEKANSMALQAKLDSIAKEHGDLYIDGIMPVFDPLKARRFDSSWNWVRQDALTMYYDIIFGRLTTVDREITARCIHLLNRADPEMLAYMQYNIDQCDPSKGDTYKLAKEFGQQLIDNTHQFIGQPPVYKDVTFPTAPHTEVSSKGDIVYTEVMRENVRKLEAYVEEMARSDTVSGPVNIQKVQDDVLKLWTIVKSQPEISQEQKNRIKALYEGVVRSLRNKGSEPRPRTPRNRRSSSQFLRPQISGIATVSADKVPLLHLKRKVGTNWEYSSNLTSVYLDILHEIATAGTTFKDKNALLTGVGKGSIGVEVVKGLLSGGAHVVITTSRYSRSTVEYYQSIFQTFGSRGSALTVVPFNQGSKQDVEALVDYIYSTLGMDLDFILPFAGIPENGREIDGIDDKSELAHRIMLTNLLRILGAVKNKKASRHFVTRPTQVILPLSPNHGLFGNDGLYSESKISLETLFQRWASESWGEYLCLAGAVIGWTRGTTLMGPTNIVAHELESFGVRTFSAKEMAFNILGLMHPLLFSITQVEPIWADLNGGMDRLPDLADITTRIRTSLTKKSDMRRAIARDNAADFKILNGVDAERLIQTVDVLPRANFRFDFPALESQDSLVDVTKLRGMLDLDKVMVITGSAEVGPWGSARTRWEMEARGEFTIEGAIEMAWMMGYIKHFDGRLKDGTLYVGWVDSKSGEPVDDKDVKGRYEKDILAHAGIRLIEPELFRGYDPNKKIFNQEVELIHDLEPIEVTADEASKFKLQHGEKCDIWAGEGGQWFFKLKKGACVFVPKSFSFSRKVASQIPTGWYAGRYGLPEDIIAQTDQVTLWNLVSTAEALNMSGITDPYELYQHVHPSEVGTSLGSGMGGQVSLAKMFTDRRDEKEVQNDILQETFINTTAGWINLLLLSSSGPVKIPVGACATALQSLEIACDTILSGKAKVMIAGGFDDISEEGSYEFANMKATSNADAEFAMGREPTEMSRPTASTRSGFMEAQGTAVHIVMSAKTALELGCPVRGIVAFTSTSTDKAGRSIPAPGRGSLTVARQVPSKHPLPILDLKYRSRQLSFRRSQVSQWLAHEHLQLQDELEAQKASGHAVNEEYYASRVATIEQEAARQEKEALATYGMLEGSDPRIAPLRRALAVWGLTVDDINVLSIHGTSTQANEENETHIWNSIFTNLGRTPGNIVPIMAQKNILGHAKGGSAAWQISGLLDSINTGVIAGNRNADNVDDHFQKRSYLMFPSKTIRTDGIRAGIMSSFGFGQVGGVLLALHPRYLFGSIDPAVYEAYKERRAVRAKLSYKAMSEMMIKNNLVQIKELPPYPLALEDKVLMNSMARARPDAKSGSFAYTTKMEAPIHVDTANFKTVSEVLAADALKKSASCSEEFVGVGVDQELISSVPSHNPNFVSRNFTDAEIAYCSAQPSPASSFAARWVGKEAVFKSLGVKSKGAAAPMKDIEIVNDKDGVPNVVLHGEAKTKASEKGVSKVLLSLSHSENVAIAFAQAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEM4</accession>
    <name>A0ABQ8VEM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_833867</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF2">
        <property type="entry name" value="FATTY ACID C-METHYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4491722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="469" mass="52801" checksum="2D9A9B1762E1DE9E" modified="2025-10-08" version="1">MPATTITNQPCVRFTPGFSKSVQPASIFALALSNPRSWLARFARTSILSVLSDAISVGQLTITDSEGSRTYGRYRKGSNTVQLAVINDAFWLRLMFSGDLGFSEAYMVGDIEVEDLKSCMDLWLDNQTGMEETLSSSFARISSAASGLYNSFFGQTKNQARLNAIASYDQSNTLFKAFLSHEMMYSCALWDDAEGGVRGDLEMGPTPGDLEAAQRRKIHHVLRKARVKPGHRILEFGSGWGGLAIEAVRTFGCEVDTLTLSVEQKTLAEERIRAAGLENKIRVHLMDYREIPPEFENAFDAFVSIEMLEHVGAKHYQTYFKLVDFALKSRDATAVVSASTFPESRYTGYQSEDFMRRYMWPNSCLPSATALITAAQVASHGRFTLECVENHAAHYPRTLREWGRRLEKNLSQEMIAQDYPALRERANYDAFRKKWQYLFVYAGAGFAKGYITCHMLTFIRQNDCPELCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEP5</accession>
    <name>A0ABQ8VEP5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_838370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="1">
        <location>
            <begin position="11"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="205" mass="22426" checksum="DEF41CF0CA8BE599" modified="2025-10-08" version="1">MALQPSLRPLIIAGSAHAPHTLDIFLDYVCPFSAKMALAIESVLVPLCADGGKYGDKVKVIFRPQVQPWHASSTFVHEAGLAVARVAPQQFWPFALALFKQQGEYFDIPTSTITPLEVRTKLTKLAESVIGSSLANDFKDLLELKGSPNGGNAVTDDLKYTIKFSRQNSIHVSPTVLWDGLVANEVSSSWGEKEWNEFLATKVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEV9</accession>
    <name>A0ABQ8VEV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_895832</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045088">
        <property type="entry name" value="ALAT1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751">
        <property type="entry name" value="ALANINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751:SF29">
        <property type="entry name" value="ALANINE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="86"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4491812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="475" mass="52121" checksum="BF7BD946DC328AAD" modified="2025-10-08" version="1">MAPLTIESLNPALLKVEYAVRGELAIKAEEYRTKLKTADHDLPFDRVISSNIGNPQQQGLDQPQITFLRQLAALMEYPALVELAPGVFPDDVVKRAKQLQAEIGSIGAYSHSQGVPLIREHVAKFIEERDGYPSDPKNIFLTAGASAGVSLLISMLISSPDSGIMIPIPQYPLYTATIAQYSGKPIPYYLDGSSDWNTSLEEIKVALDKAEAEGTKPKALVVINPGNPTGALLSEDTQIELIHICEKHGLVLLADEVYQSNLHKPDTHPFTSFKKLVSQLKSTVPLVSFHSVSKGVLGECGRRGGYFECTNFSPEILALIYKMVSVGLCPPLQGQIAVDTLVRPPKEGELSFPKWKEETDKIHAALAERTKIMADRLNKLAGVECVNSPGALYLYPKITLSSKAIAEAEKHGKQPDAFYALQLLDETGICVVPGSGFGQREGHWHYRLTCLCPGVEEYVGKLEKFHNRFIDKFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF17</accession>
    <name>A0ABQ8VF17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine nucleotide exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_837896</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the synembryn family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019318">
        <property type="entry name" value="Gua_nucleotide_exch_fac_Ric8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12425">
        <property type="entry name" value="SYNEMBRYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12425:SF5">
        <property type="entry name" value="SYNEMBRYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10165">
        <property type="entry name" value="Ric8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="529"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="594"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4486843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="616" mass="66988" checksum="367A6B01080E4ED7" modified="2025-10-08" version="1">MADVLQTYTELSSSTPRSQVTSVLQSIINALPFTFNQSSRAELIRLLLKDLKILGPKSRLAAKDAGQALLAVKTLGRIPSGSEPLSEAGNLSTLLSLSASLKDEPEASTEALRCIANTLLLFDHARQTLISKEVGGGDVCVSMLDKATTPEQIFTLARILFFLTVSRSAFIQSLIEEKRQGRNIVDIIAAKLDATMVSILAGTKFARDAMTDLLKIAFNILLHYPKMVDSEPSSEAKEWDDSWSVKLEGLLPPLLRAYHTIPPTFPMPLVAPLTHIIHALILIPVNPSLRPIWFNMIPPATGRSSTSSRTSSSRKSTNINSASSSPVMGSPTLGPSESPDRRSTTSIKPSTLDRALSVISAGRKSLSRSPSPSPPSTSYDVFQRTHDLLEITFSHHFPDNSDPDSQEVREAFKQELEATGAPSDTSLDDILSPLIVLCTRLCLADESNRVRMREWTVPPDLDRTNPLDERADFLGRCIRLLGSVYHTRLKDAVGEMLYAACDSDAALLSSLFGYGHVAGLLFNKGVMSAPPPPSTSQSSSAPDPSSLTTGQREINPITGTYAPTGPTVSATADMTEEEKEQEMEKLFVLFDRLERSGSMPASQNPMRKIIEKSMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF71</accession>
    <name>A0ABQ8VF71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_832729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8719" checksum="627627C47E2CA179" modified="2025-10-08" version="1" fragment="single">MIRKAFLRAFCVFMDGARSENWHVPTCPEFPECHASQYPNTSDISMFGSQYQRHSSVSMSRYQRRLDVSMSQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFB1</accession>
    <name>A0ABQ8VFB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAC3/GANP/Nin1/mts3/eIF-3 p25 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_346943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="114"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="951"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="967"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="980"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1004" mass="111227" checksum="F73F53B0A31B2FCC" modified="2025-10-08" version="1">MKSSGVGASVSANALSGGTGGAVKHRNKQWVADGARGRGRGRGAVFVRDDRPSEVQPSDPFLESQESRDLFWHTLVKSREAERLDLICRGLMDDPLVPKRLSDAITLVGTCADMCPRFERYRRERENNLFPWECLPAPHGKRVWHGRAVKAYERAAGDKTLPSDLRPPGVLKRTLDYLFGELMVREGFVRTYAFLRDRTRAVRSDFVMQREEGAVAVECHERCVRFHIVALREMRGEKEFSVNLEEQQLMNKFYTDQRSVFTSPNELEMWIYHRLIHIRDQRERNDDIPSHILTHPVYILTSAFRAHVQAQSTPITKTSPLVVGEEGMRIFGELAGWLMGGKGKRGMVYLVACLLEHLFGRDRIEDMESVRGGLALVEIIDGREQEEVQEQEQEQEEPPAPPAPSTSAFSHLTTTANPFSSPSVFSAFGSTAAVPALFPAQGTSSSPDPINSTTPSTPLLNPPPAPRPLPISLPPTPTVPSAASESTTNPTIVPPNPIPHHPRLSLLKTSLSTPPALSLSHSSSAPPQALLSPLTPSLKGFGRVGSVGGSEGLDGSSSRDGEHDRGVSGERRGEGVIERRSESVLTRGGTRGKSESESESRSTNGVRRRGRERKRYQPTPTPSPDSGSESDSESDSPFPSTKTFTPASTLASAPSTMGRTDEDLVSRLMETQSTHRLRWAPNTFLDVWRSHVRRRGGRVAGVLRVLDLEREVSASASVLVPATSASSVLVSASAPSTLASAYTLLLVLNPAVDATAIWAQTKFGVPGSGWWGVVGADRDVTGNGKGKRNRRKRNAATRNEVEVFEIPLLPRLSTPTPSFTYTSPALIIFELTPLAGVRDELERKYVVLGDCTRLRGVLEGVKRRGRGWRRKEIEGREWKKEKKEKSEEWKNKWNWSKDQSESEQEEHGYLKEEEQDDEHNTEELYREKWFIPSLILIHWAETEEEEIPRDLGDVISRYTQSPPPNSTLPQTTLPTSLHSPPTPSSPSHPPPPTSMRGSIGRWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFD0</accession>
    <name>A0ABQ8VFD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_837272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="283" mass="30995" checksum="E60F918B5A2081F3" modified="2025-10-08" version="1">MSIDISPGQFVTSSDGTKIWAHACGNPSKPAVVFIHGFACTADAFYKQYSNAKMLENLHIIRYDVRGCGRSEGPLSGEAYSSELQADDFKAVTNAFKVAKPFVATWSLGGIVPPDFIAKYGPDSLSGHIMMGSFPHRNMHSEVVHPVILSLIPGLMTEDIALFAKTLPEFVLSCVSPNHKLPYDVYTQWLGGAAPRAPIVRQSMLGRGQDSTAIMAVANDLPYMAIQGEDDQHLVPKNLEKWMKDHLARSEFHLIPGVGHAPFYEAPDVTNKLILDFVEKHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFF6</accession>
    <name>A0ABQ8VFF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="557" mass="62801" checksum="F74D7F8F7A749E30" modified="2025-10-08" version="1">MDVTGDESSVDDEPRTPPAQSAASDPGATPTQQNPEEARTRKATQLQTAKSISKKTARAASRAARSRTPSTADDDDDTGAPLKSAHLLGNRTLEEKIIQANNDAIQKMAESNAQMLAEFKASQTEAMEKTIQVAVVSGLSGLNQNVGRLAESLETISKNQSITSQLLSRLEGRLDGERPRSPTRSSSHRRPMNTNAGHADDTQAEGSNQNAASAKGKGRMEVDEEDDDEEVEYADGEDQAEEGIALKKKRKLTKTRKALDLQDNIRHWLNDLIGGQQYSLVVTVTDEDTKTFEETFTQDPLAKPCTVNDFRYYINGKPSAAWNKGAAFVFVDYVKQEKLMKIPNKATHDLLRKGFMMRIRTLHHYHTRSKFSKEKRDRSANKGRKYSRKTSTFYQRRELLNSLDPLRQYIRYLDAIGIVGMSSDEEDKEGPLSVPPQYKTTRPFWRGEDLEEFFILLDACHILIRMRNESPTGTTYSQGAPPRYRVRTQRESENNSFVKGLPRNFYRAGWLEEKEPGWQKGGEGFVNMIIRPKPAKELVFPAELKEELKKNGYVFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFH0</accession>
    <name>A0ABQ8VFH0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046732076" evidence="2">
        <location>
            <begin position="22"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="37056" checksum="1EA720AFF91B64A8" modified="2025-10-08" version="1">MVHSRAVITTLLAVGTASVLAAPVPESFANVLAARGPEDQPPPPGAFGQQPPQGPQGSHYPPGGFGGQEPQGPMAGGPPGAPGQGPQETAGPPGFHGPPHLGGHLGIPHGGPEGMRFPGAGMRGPGPHPPPGGMFPPGPPGGQQGPPHFGRRQMSGQQGPPQSPPPMGQHTQGPPGGPQGMQQDAPPPDMAGAGGPQPAHQTFGRRQSPQGSPSQDHMDGQQGQQGGGDGGHGEQGPPGNGGMKPQGQGSPDSRGGKGDEHGRHKHHHHGPGGKEHGPAGGEQQQGSSNAEESQGPQGHRGGPDGHARRATHEQGQDSPQGQNGHQSQNGQQSQQGHGNDNHAQGQQNEGHRHRRSPYSYYGEDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFH4</accession>
    <name>A0ABQ8VFH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="256" mass="28945" checksum="B4F2D984759A52CA" modified="2025-10-08" version="1">MEPDSTTDSDKGSPAPSGWWRRQTYDYCSYYLDGDGIIQKIYHNPNIEESRTRGRAKTPPPQKGALKKTKNPSFAKNADRGSTPVSFKPQARPPKYFLQKNPRTSNITNEPFGPTKLETNRFRSHDSEGETAWHCSQSPNDLDAPPLDTATPRMLGTIYVHRDTRDGGYQVWVWCNNEGGERELWWRPVDLENEQFVHPKIATRSLKLTSGGKPSWVLNSMLTTYRTRSAKRSRLRPATGSTQGFTPDAESVNAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFK7</accession>
    <name>A0ABQ8VFK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="56997" checksum="84D7941FC551D365" modified="2025-10-08" version="1">MASTSSPTRSSASTTLLPTSLEAQVLLAGIQSKSTLPLFFKSAIFQRLLEGDYSPPIVGSDNSPDYNGSGSFPAFSYPCSLVPFCFPPDTSRLLSVASGLDLFCSTQLAVRTLQVLADDSPPTESGEVYNAFEEAAPYLIYIHDFWMGRANCPLFAEQVLLSAELLSLGLPAFLRDNLTQQWGIPPEHRSSTSDVQSFERFPAIPIPFCLRFREGSAMKRMVPSQDLDPFASLHGQGVSPAALKAISPPKVSDIIPLPSATKAPAADASSFFSSPHSTHSKDSDNELLSGIPSADSAPRASSSTKVSVGSKKPKSKTTIKVVEDSKASNSPPAGTAYKRVRLPPRSRKIAPITAKGKSRQVVVSDDDSASNEVESEDEEEDEDEEEDSAPPPKHLKMTSSISASVPRCSAAVKPVPERSPDSTFQPVLLADAQGRLRLPEQSTGVFTPFPKFAHARNSASLTRENPLLAINPDFVKLGSILETQNARFMMQDLMQVNQVIRDPSIPSQACVSALARGDLEANSAPLPGYKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGD5</accession>
    <name>A0ABQ8VGD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_325364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4493308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="426" mass="47768" checksum="BD4BEE2131E66EE4" modified="2025-10-08" version="1">MESSSYSEKRDEDSDIPSRHVEIAASALDTGAQFANGAEETIDPSEAIRIRRKIDRNILPMMCLLYLVQFMDKTTLGYAAILGMNQEAHLTTDQYNWLGTIFYLSYLVFEYPQNLALQRFPVGKWMSINIFVWSVALCSHAACKSFGGLFAARFILGICEGSITAGFMIVSSMFYTRKEQTLRVGYWFLMNGTAQIILAFVAYVCFWLFFPDSPTNAWFLTPKERALAVNRIKSNQTGVENKHFKKEQMIEVFLEPKTWLFFIFSIVDNIPNSLTNQGTIIITSFGFTTLQTTLLGCVSGVIEIATIWSGVEISSRIPNSRAYVGAVYFLPSLLGVFLVNLLPWSDQVGLLFSVWLGTIQITAFVMSLAWVSATTAGHTKKVTMNAVMLCGYCIGNAVGPFMWQEKYKPRNHVPWIVIGVCYASGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGT5</accession>
    <name>A0ABQ8VGT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_830029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="229"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="504" mass="57742" checksum="086F9890438B0349" modified="2025-10-08" version="1">MPPYYRTQVIISLGRSAAEVVATFAPVPGLYAAAGMLCAIMELTENVIANRREARQLRDRCHTLLQAAKESSEVGNENMNNAFQMIQETLSKVQSKMDTWVKLGRINSFLQQNQIKEDIEKCHEGITDCLTHFQLVSHMEIHSWQEEFSVNFAMDHQEVITLLSDVKESQNFIQTTTVDNNTMLKEMMVLLQSALFENKHVADKTHNGLASNLYELQQKTDTLLPNMNLQSGEVVREGNFPVSGTAAMDIYKGRYLNREDVAIKVVRAVNSNEASRRRFMREVKVWTDLWQRDKGKHILPFYGFCQTDGPFPYMVSPWQSNGTALQFVKKYDLGVDYLKMIKHIALGLQVLHEMKVVHGDIKASNIMISPEFEPLLADFGLSQIVEDITGIPFTQSRGVSDSYRWFAPEVCKGQGVLSARSDVYALGMTILELFTHQQPYQKIKHTTEVVIRREKGELPERPNETRILQRGLDEQLWMLLEDCWRTTASERPKIDEVIQRMTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI56</accession>
    <name>A0ABQ8VI56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase II subunit RPB9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA-directed RNA polymerase II subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_763091</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10508">
        <property type="entry name" value="Zn-ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034012">
        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="13">
        <location>
            <begin position="71"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4495314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="125" mass="14273" checksum="5383818837FD0FBE" modified="2025-10-08" version="1" fragment="single">QASLQFCSECNNLLYPKADPHRRIMVFACRICQYEEASENKCVYRNDLLTVTKEQVGVTTDLGSDPTLAHSNVECPRCGNEDAVLFQDQSKRKETRMILFFVCSKCNHNFTDPTVQSDTRENEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI60</accession>
    <name>A0ABQ8VI60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ALIX V-shaped domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_302967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="36048" checksum="F71D045F296BC25D" modified="2025-10-08" version="1">MGLRLTFYTDLSQLASTLESAVKDFVERRTREREALVRQLEVEKRLSSGGAMSVSQRGSGPPPLPPPPPSSAPDNSNDLSASLAGMNISKPPPPTPSLYASSYASQQTPSQTQWRNTPTPPVSQSPHQQQQTQSYIPPSSSQPPPQPPYSPYSQPYSSYASSPAIAASPQQQPQRQQYGNFPPPPSLPSPPLLDPYASLDMLNSISPPALPPSSQPQRQQIYGNGFPPPPPGPQAPPQQGYSGQGSYGRYSSPPPPPPPSHQGYVGYQSPPSHPAPPPQQQQGYGGYGSPPPTQQQQKSYQGYQGFPPPPPQSQQQQNYPGYQDPRGYSSYGSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI64</accession>
    <name>A0ABQ8VI64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6830 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_762707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049233">
        <property type="entry name" value="DUF6830"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20722">
        <property type="entry name" value="DUF6830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6830" evidence="2">
        <location>
            <begin position="131"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="412" mass="47028" checksum="9A18A11768954C65" modified="2025-10-08" version="1" fragment="single">YHECIVPSISASGPIMQWTADTTEHAHITLVKDPARSGNNHDFEVQIWRHLDCQSRVRRFDLMTAMVDARVNFRLDNIEGDEGRGDIGHDREERDEEDEEVDPKISSSEELMTHLHPVSQKLFGSFRPKQNFFLEARLLKQDVSALQPLRIFTDNISGEISAFKVNHDSDLKTLTIEQVSNLYSLPDFYGACFDFLERIQANTQTFAIGGRRSSNQLLSLPFTRVKVWSRVCIQTKTYFNTDILADSHTIFAAPPSPGWEFGQQNAAIVNIDSSFEWPRSSLGGHCVVLVKIIFTIAQPRKPSLPTHRFLAYCERLDVINQPPPPFEYQSLPGYNALPSHFSDYSSGCFILKRARRVDGTPFGDIIPVSQFRSLVDICPRYRSTPHPSLTRSSSQYHSDEFFLNKYFNSFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI96</accession>
    <name>A0ABQ8VI96_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="47"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="163" mass="17261" checksum="AB096C87EE46037B" modified="2025-10-08" version="1">MNIPIPPMLALQAKPGSFPFASKYVPLPHNFQAVLGSQVQDTNTGPTSSNRSATSTNGWFAPLSSVDGQGAPVSPISLSPTHAQIWSTNGQIFIRDLESAFGTYVNGTRISGDVALADNDTLTLGIVVGRNTNTPTYVTDEHLKPVIAKVTCIGVSSRARQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIQ0</accession>
    <name>A0ABQ8VIQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 15 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_895154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4495515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="44807" checksum="88A2CFEE6A0B4C90" modified="2025-10-08" version="1">MAVLFPLSTPKRYVITVLATIISLHYLLTIVYEDYGRISSFGNINERTGERHGNDNVSMLNYNSLQTFQNMTGPRANATFVLLARNSDLAGVVNSMQSAEDRFNRHYHYPWVLLNEEPFTDEFKERVTVLTRAPIFFGLIPKEHWFQPDWIDEERARAGRQKMMAQRIIYGGKYRNMCRFNSGFFFQHELLQPYRPDVKFFCDLDYDPFLYMQEHDKVYSFTISLFEWEPTIPTLWQTVKDFIAEYPQYVENHNAMDFLSNDGGKSYNLCHFWSNFEIADMNFWRSEAYTTFFEYLETKGGFYYERWGDAPVHSIAAALFARRDQIHFFRDIGYRHEPFQHCPLGEQWTRGRCSCDQKDTFDYTQNSCLKKFEKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIV3</accession>
    <name>A0ABQ8VIV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="270" mass="29884" checksum="D3402FE84036805E" modified="2025-10-08" version="1">MKLRSRSHHRRSQSQSHNHRLTAQTSPPPAKQVGQLSPIPASPNGDHGCSKSAQTKAMIMQGIKGSSVFDIDNAVIWYWPGSYFELDGNWAIPVTTVNLQDTIRDDKGEHPICFCGYVMKLQLIDKSQKESLNGTFAYICRMNGGCGYWNDTLKRYQSKLKFGIYTMDDQRHMTIVPYLSPISVLSAPTTTVLDAALGTNEAEDTSDSDGSDIQQKGVALLSFLKGKEKEVSRPFFFSNLAITEKNTTTTGAAKHSAVVLKTKAFKYPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ14</accession>
    <name>A0ABQ8VJ14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="311" mass="31610" checksum="41A939DAF6EA0671" modified="2025-10-08" version="1">MRFPFITRRAEEPQDSHRRYRRKGGGGKGSGKGASGGSTGSSSRGSSSSVTIAGSSRSATSYGSGGGKASTIPSGQIFAGRIEGGGTRDQVFGSSTYGSGYPGITGRGVAGRGFPFLFWPIVWGGAAGIGSTAYLHDTEYGSPDNTSRPGGPMMTSTFVSSASTSSNATLSPTTFHILADNTTLISLISAITTNCSSNINTSSSSSNSSNPSPYNASDPNAPQPESAIGYYRASSVVLTLNGYNNSAALGSDENATNTPLPTGIDTTLEDCLNQTIGAAVPLVDGARSVNIGVGSVALLSMLFVVLQRLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ20</accession>
    <name>A0ABQ8VJ20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_918921</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="316"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="5">
        <location>
            <begin position="410"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="414"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="564" mass="62997" checksum="BD4949D66EDB1363" modified="2025-10-08" version="1">MSSNIPVRRTTRGTKATKDSENANAKPSRIMTRARTQASSLLAENARATATTVASRAKTVETGGEKTSVKRKREILGEVTEPNSRKPKASAKGKEKAPSGDKAGPTATASKSRLTSKTTRAPLREVGGTASVQKPLRSKPVAGDRQILGIIKEDDDRDEVMIDETRAPAPLHATQPAIFKLVPQTSAHKDLLRRAPTSLRDDIDREPVFKKRITEDGEDRQPIARVTHRLPTTLDESQLEEDRIATELADVHEDEEGASLWDDLDADDAEDPFMAPEYVHEIMEYMKELEIRTAPTPDYMDYHSELDWEKRFILIEWILSIHSRYNFLAESFFLFVNVMDRFLSLRPTVALSKLQLVGVSCFCAAVKFEEGVAPSTDELVLLTGEIYSADEICKAERYVLKTIDWDLSFPGPMSWLRRGSKADDLDPVARTFAKYLLELACFAPELVATPSSLVAATSLWLARLTLGREEWTHNLIHYTSYKEREIIPVAEVLLSSVISPVQVEVLYKKYASRKFMKCSVYVRKWALARFEAGAEVDLIAELPGIKIEIVESRNAKIAAGAAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ21</accession>
    <name>A0ABQ8VJ21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">UDP-N-acetylglucosamine transferase subunit ALG13</fullName>
            <ecNumber evidence="4 12">2.4.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Asparagine-linked glycosylation protein 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ALG13</name>
        <name evidence="14" type="ORF">C8R41DRAFT_827470</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 12">Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-alpha-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23380"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19510"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57269"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.4.1.141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Heterodimer with ALG14 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.141" evidence="4 12"/>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039042">
        <property type="entry name" value="Alg13-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12867">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12867:SF6">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4495648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="19047" checksum="DF01888AED965DF7" modified="2025-10-08" version="1">MLAFITVGSTRFDGLIKSVFTPSVLASLSDKGYTTIVVQCGNSDFSYNHLLAQGEQSFRLEKDGVTIECWKFKPSLQTDYERADLVISHAGSGTIVDVLRMDKPLIVVPNPTLADNHQQELASALEKLGHLRSSTTSQLANTIQEFDASSLTKFPPFDGGKFRKLLDEEMGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ42</accession>
    <name>A0ABQ8VJ42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_762403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF5">
        <property type="entry name" value="DEPENDENT EPIMERASE_DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="323" mass="34595" checksum="A5CBF9C0404B5C2D" modified="2025-10-08" version="1">MSAYIQNKLAKGEKLQFFITGATGYIGLVLTEFAIAQGFSVRGLSRSEAGDEKLKSLGATPVRGDITTHEVLARESTAADAIIHLAWNHDWTGDYNKIVDTDIAAVEAICAQIKDTGKPLVIASGCAGAQPNADGSDSDENAPLRPNLPVARRLESEINAIKKQGIHGCSIRLSPYVYGRGGKGFLVMLMGQAVKLNESLYINDGSFHTSVLHVEDAARLFIAAVLKSKTGEAYNGVGQTDVSLKDMAEAIGKVVGVPVRSATFEEATEKWSPPILPIFNYLDVRGSNKKAKELLGWKPEGVDFITDIVSGSYVPVAAYLKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJC5</accession>
    <name>A0ABQ8VJC5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_738335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18371" checksum="035B1F03492CCBC8" modified="2025-10-08" version="1" fragment="single">FTAFNILQRCNMLLRTALKAKRSTFPALARQFASVTSAAIGAVTKRFAQGDMVPFRNSQERMVLQLMQQVNLVTSTVPGSSAALVNMRNEIRALMIDQGLPSFYITINPADVYNPLVKFLAGSEIDIDYMFPHEVPSYWDQATLIARNPVVAAKFFNVYLNTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJX8</accession>
    <name>A0ABQ8VJX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_303184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="560" mass="59118" checksum="6BFC7E8834490C4A" modified="2025-10-08" version="1">MFKSTRVNKSRSSNNKALDESSASSSSLRGNDTASGSSSTSASTPVPLVTRTYAPFPAPYPYAVVTSNPVPMYEPYPAYPQQQLSQIPQPLQSQQHPQQLVLLPRPQVPEHILEHQPPHSHYTLAAVTPGNSTRHLPLPTRTPYQNGNRVEYTHDPSVRYVSSSAPSSSPRIIAGAPPGSAYVPNYPMTTSYGAPGPPDHTMYSSIQSLPPPPPHGPHSHLQQQSPSSPWYDEQHHNHPQSSPGPYPSVESISSRPGPEYGEQSPPSNSFESPSPVVPTLVPLNLSSVRTPAEYTLVDNNNSHSSTSSMSPMSPVSPTSPTSPMTPLHHMPPTSRIPPMPSMTPMPILPPPMSPHPNTPPNPVHSPVYQSVYTIPRGMPSTYLYSSTYTMTPAFQYSTISAAATNNPATIASIAYMGDRAATPASPSTESSASGSVRSGGSGGSVRSMRSTGSAGSDGSAYVPSSSSLYGPGVPGVSSSRASAGDPGTNELVRSAELVRLSEPGLAVGSAGGGDAAGGSPQRAVPLPPLHSLKRSHPYRRHPEDDKTLRLLDPRPVPSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKC6</accession>
    <name>A0ABQ8VKC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Quinon protein alcohol dehydrogenase-like superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_824938</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="219"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="355"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="520"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="168"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4496832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="575" mass="63514" checksum="73FCCA0237A448FD" modified="2025-10-08" version="1">MTVGIYGASLCEACTCLGAITPSSMSSLKNSQFGKRLRAFRGTGDENSPSRKRRRLNLGSLSSPTKSPTKRIRSLATAALDVTNTPSKRHKTRYSIGSEDRFVPYRDQNNLWASYSLDENANKPSPSVRQPMRRWSLPDPETERADDLFKSVLRSELAGSPIAYHSLSRKSQFENSPSRLDDPTDRSYQLSPLHPETSSLINKPRPEYRNVAKTPFRILDAPGLSDDFYTNLIDWAPSGVIAVGLDKHVYLWTGDNHKGGAKLCTAFDSKDEYTSLAWMKSGSTLAAGTAQGHLEIYDTSTLRLIRRYKDAHAHVAGKRIGSLSWTSDTLSSGSRDRMIKHWDFRDSSAKPFKQSAAHTQEVCGVKWSGDGGIQASLLASGGNDNRLCIWDLRGSIRESSTSAGWSSFVRNFVSDDEGVSGIAPLYRFRQHKAAVKGLAWDPHLSNVLASGAGQQDACIRLWNTATGTMTNEIRTGSQVCNLLWSTNSHELVSTHGYSTQTIPNQIRIWKYPSMNMVASLTGHTDCVQYVSLNPNGETIVTGGGDETLRFWNVFPGRTSGAKDENSRLDYGKLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKR6</accession>
    <name>A0ABQ8VKR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_737522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="112" mass="12844" checksum="E1BDEE64A49F6731" modified="2025-10-08" version="1" fragment="single">LRDYIPAKVLARVSTDVKTRSDISMESEIATMVFVRSRTDVAVPFVYGYCPTRENAIGQPFSIISFVEGETMNSSIWEDLPLDVKLRTIRDYARIILELSKLKFDRIGSLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKT9</accession>
    <name>A0ABQ8VKT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="13">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_824483</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 13">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="938"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="977"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1003"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1050"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1076"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1104"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1130"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="142"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="16">
        <location>
            <begin position="938"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="88"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4497034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1172" mass="129111" checksum="499BB2D9207F1E1F" modified="2025-10-08" version="1">MPDIPLRAFRNKQNAKAGYELLAGENPSPSTIDTPNENNTGMNRSVSRVAAVANANAERSRTNRARRAKHPQRLYVDDDPEEAIGLLESSREREEEVEEGMMLPDSSKPPLSRLKKPPTSKSPKGTLYTSRIIPFHPLPSLQSKYPPNIIRNQKYSIITFFPKVFYEQFKFFFNLYFLLVALSQFVPALKIGFIATYIAPLAFVLCITIGKEAYDDYKRNLRDREANGQKYIVVDPPSISPHLSTRALPSSSLLVGQLVRLQKNDRVPADMVLLWTSDPSGTCFVRTDQLDGETDWKMRLSVGETQGLGEEGVAKLGSGEAEIYADAPTKDIHTFIGTLTLHPSHVSPLTAENVLWANTVLASSATIIGFIIYTGPETRAVMNTSTAGTKVGLLEVEVNGLAKILCTTTFLLSLILVALNGFRGGVFTTHTVVSVFRFLILFSSIIPISLRVNLDLGKSLYSHQIMTDSTIPGTIVRTSTLPEELGRVEYLLSDKTGTLTRNEMEMRRLHMGTMSYGQDSMDEVARQLALAFASANNGNDDDHNNTHTRGSSSVALGHHANTIGGGAGRGRRDMSSRVRDVVQSLALCHNVTPVTNDDGSVTYQASSPDEVAIVTWTQTIGLTLVYRDRTKIVLRAEDPARTLLTFTILAIFPFTSTSKRMGIVLLDHSTSDILFLLKGADTVMAPLVQRNDWLEEETGNMGREGLRTLVVARKKVGKEVWAAFESEYAVASTSVGGTGGGSGDATTDGAVSRAEAQAQVIAKYLEKDMELLGLTGVEDRLQDEVRSTLELMRNAGVKVWMLTGDKVETARCIAISTKMVSRGQYIHEVSKVTSPTTLKSHLDFLQNKLDSCLVIDGESLQLCLSLYKNEFIEIATKLSAVVACRCSPTQKADIAKLIRAYTGKRVCCIGDGGNDVSMIQAADVGIGLVGKEGRQASLAADFSLTQFSHLIPLLLWHGRLSYLRSSTLAQFVIHRGLIISIIQAVFSAIFYFAPIALYQGWLMVGYATVYTMMPVFSLVLDRDVSRETALVYPELYKELVKGRVLGYKSFFEWVMISVYQGAAIMIMSLVLFENEFLHIVSISFTALVLNELIMVALEITTWHTYMIISEIVTLFFYIISIAFLPEYFDLSFVITLGFAWKVAVIVAISALPLWIVKVVKSRVAPAASSKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VME8</accession>
    <name>A0ABQ8VME8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP12-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_827401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07542">
        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="31969" checksum="CDE3C77F5EBDA7A4" modified="2025-10-08" version="1">MLSVGFHHVRAFRPLGVSKLRYTSLQIRLNSSLLDGPPVTETNRAEATMKRFWKTVGIEDRREGIAITLDKRALKTPSGHTLLLPHNKRLVATLIATEWENQRIVLKPHALPMTSLASRAIDNFADSESRKNVRQSLIQYLDTDTICFYQDYPPPLIRQQETHWDPLFAWVEENFGAKLVKFTSILSNSQSEESKKKLSLVIDDFNQWEMAALERAIHATKSFVIALALVKRRLNVDQASDAAGVEVNSQIERWGEVEDTHDVDFHDIRRQLGSAASLLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMS5</accession>
    <name>A0ABQ8VMS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="386" mass="40021" checksum="9FAEF59D9B0DAD67" modified="2025-10-08" version="1">MGIAESISAVGIAGTVTGLSYTQATAQQKEEEEEAKRAADEAAQATAAPTRNSNRDKQRAGADENGPSRGAFPVSGTLGGGGNGRGPGPGRQKGGGTTASDTGGRQDGGNRNTTGRKDGRGGTGKQRAPTEQSNRPHSASQKKKKQNLNRRNQLPSAAEDNVPSSDAQNPPTTVTQSTTPVKGQRRGGGISKKQNASSVPGQTDNETEKPAIDSGAVATMQEETAPAAAVDNKSIAKTNRRKNGKSRSNTRVPQSSTTSPSLATNTTSPSALSPPPAQNTSSLHPHPLSNPQVPRNESRARSRKPRGRPHTKVDTVAPSQLQSPSSQIVQNPSKTQDHPAATNPVVSPNPSQARQGKGRGGRRANIERSTPLVSSSQLNHPTTEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMV4</accession>
    <name>A0ABQ8VMV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_791532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="56"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="524" mass="59224" checksum="7346BB65B1CD3586" modified="2025-10-08" version="1">MTSPKSNHVRNATVLGDQKLTDSPTSPTFSRESSTDSQNSTTSSNFVPPLTAHPFRTLVLCFDGTGDQFDSDNSNIVQLFSILKKDDRDTQMVYYQAGIGTYTSPQIATPMMAKFSKTIDVAIGWYLDAHVMGGYEFLMQNYKAGDRICIFGFSRGAYTARSLAGMIHKVGILPACNHQQVPFAYKMFTRDDEVGYAQSAAFKKAFSVDATIEFVGVWDTVNSVGLIPHRLPFTRSNTLVKTFRHAVSLDERRAKFKANLWNSPSDVITNNIEETGKHSHHHHHHLDREYLRFFKDPNQKTDIEEVWFAGCHCGKFYTTYTFTRSSKPVIDVGGGSVSNTETTNLARIPLRWMIRQCFKTNTGILFHSEGLRSLGLNPSSLWPKVEPRPALTAPVTPSRIRPIPRNPPPPTSHELSKESSPSVVKTEEELDLEDSMSPIYDQLSLAPGWWALEFLPVKNKFHDGSGKFLTEIECNLGRARRIPRQKQGVKIHRSVKMRMEAQYENGKKYIPRAKFDPQYVTWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNW3</accession>
    <name>A0ABQ8VNW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_252380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="882" mass="96331" checksum="89C78CF352E7E2D9" modified="2025-10-08" version="1">MGNEQNTLYSCKCINVQLKSSAPPTTGAQSDLPPASAWTTVFVPRDEDIKIIYPHLTLRSRHRAPYIPDPTRCARYTTVTCLSCQTLVYRIHQTVLLDDEVNIREGPIIAKGWVFEEVLRSSSGWLEVSTKDVGETVVNQQKAPPQFSELFGIVLPASTSTSSLTPDFDSTLQSISQSQPVPRYQLPPIPAIFPEPKSTRSLFTVLAAVATRHSNTIRTEAEEYIDRIVKEKVEEIKRAEAQLKRNVLALMTAYSDGIKKAEHEQNALQEGSSQTEAKKEKKEKAPSPPASSSTPVFTGPPSSVIRDFIPMRITPSSTTAPTIPSTSSPRVSRPSPLINGSLPRISALSASLATSSFHHPRAGNAIADGASIPPTNPSRTTTDADSLHSLRSASSATLSAPQDLTNVFQYPRLFDDQVNTAASFRYFQLEDEMMRRKLEAERDKKARDGLPATTSAGSSRIPAPSASSSRVNRAVLKTEEGHRNDKVTAVEPQEKLKESELQDQSQASPKSKGKRKVTFDVQLDPPSNPVEDGTTKLSEEMLFDYEEETNEQDTTSVVLPMSESVSQQGAVSRLHERNSSGGGSPASFTGPISASLPASSHIPLPIPSRIPPRTTAAAQNGSDNLKSNNAEANHNQTDPASDIAFDFTATNLDAPSAARALKRDRHTQILNLLAASLPSHRAAWAGKNYEAFVRGAYAKTNEDYDDDEFDDGGDDMKTEELQPELSRAGIPSSVPVTINRPYKAPPLSLASYQPAVLTENMDNNRTSQADIMYKKRASAAALRRASYAERDIERGVDPGMFDYLLAVHHEEDEEDEDQLDGHRDSEHGENGDSATNRANSEDTNGSGRGQTGNRKGRDRAHKILEAQAKNGVPDDEMWRSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNZ6</accession>
    <name>A0ABQ8VNZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_757987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="507" mass="55397" checksum="6BC662D8360A23E9" modified="2025-10-08" version="1">MPSPLPPALPPSPPASRSTSPVAGPSVQPAKRKSEVGLDTDRPKRSKTESTATTHRVSHLPPTHYLPRSELAEDGEVAEEPNSVSHPIQSRATPIHPSPDAPVTSFVPIRRPKRGHQHNVQLIPTLHEKYHQAGRKLKYSGDARFWSTYPPSHKEYRPIPNAPPPNSLYHIHGGMVAKLELMEALVMFVYSSWCKEYGRGGIYTDSWLTMEGFIKWCKAKWKPEEGSSDGEKAFYGLIHMFHAFIHARIVTQSQRKLRSDLERVTEATCQAVNAAISDAPSHSSSLGAKSQSTPPMLPSPASIGAANSANSTPTNRDGTPISSEIRSASISSSSAINAPSQSSSSPSGPSIPLPFLPPQYRTGIPPSHISAAANTVSASFNLNQLATVNEVSYSLSVSIAEMQTAQVHLNFSIIARHFPRTFARMVHSTLKSTEEHEVDFEDDDGELFWPGQSITGDGLGWLCYMGEAMVQEFGKQFDYKGLKGVVPKPDQYDPRIRPPSFGMAGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP99</accession>
    <name>A0ABQ8VP99_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_819727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="46021" checksum="A1C13E51AFCA0E2C" modified="2025-10-08" version="1">MASFNLTVEDSSPLISYLPAGAWSDSPANDTLLSSYSGSSYHITSTQGATATITFTGIGITIFGGHRQNYGTYQISVDGQTVVASESSAGQDVFQQVLGTVSGLSNEKHTAVVTSSSASSIDIDYVNVQTQIGETGSQLTKSTVDDSDPSFIYTPASEWSVNDQNYFMNDTLHYTSSAGASASVTFSGEAVALYGTVSQDHADIQLSLDGQNVTFGAGANGFASTLHSQILLYYAQGLGSNQHRLVVAADPQSGTGPFIDVDAVVVYSSIPGSTTTSSSKPTSTSSQRDMTSSGKLPTKTIVGIIVGSIFGFLLLLALLLLLLRWRRWRRRGQADLRSPLTPTLPIQNPDTLEAGLSTRLGGSRLSQNSMSSFYSGTPPEEGFMQGHSRDASTAESFSSMAPINASSAVPATRDHSISSNAPIRPNLRPPPLKLPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPD1</accession>
    <name>A0ABQ8VPD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_878571</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zinc-finger" evidence="6">
        <location>
            <begin position="102"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="553"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="666" mass="74872" checksum="5E8708A2C05CB2F4" modified="2025-10-08" version="1">MSTTPSSSTPVSSVRRFKQVYVEIPPSPLHTSRRLSIPSVPSSNVNHHKGNTPVQHSVSKHAAIPSRKRKDVSLSLQLPIKKPRTEHANEGGRGIETELLIRCHDCRAKRHPSGEYIISISKIIQCTSLYQIPYKIPVTRHCRTNYCRNCLKNKYNELSFAASAQKENGETGNAHMFKCPKCRGHCNCWNCRRKTAPKSTPAFPQADVPSERALATVNDLGTAAASKGKAHKVKLAPNVTWSPLPTQLKVKDAEDRIFIREFILRFSGIPGMALTKSQLEEFEFIAGTHDLGDDDDDDDENVYVDWVSETCIKSLVISLIGVLAAEEDSSATLVMKKAMQDVRNSGANLTKIWTALSSLRAALGRPEEVSVGKLQAEKPSDDDDESSEDRIILEYPDPLPAPANHEHNVQSTRSAAAADISLVVHSAQMIPVILGLMDAVMECYAIRVELDNGTKESRERLRESREVIKLENELWKKLEESREPDPSKITVERHAHKSKVQDIENAAKVLSSAFSPRFSPLGSDPEGRVYWALTPGVSDREYALDYIVSRLPNAPKSKRPRNRKQRQQREEEDSQALREWSWFIAVWGKKPHGNGVNDGEDEPQWWGFWNPQEIRNLAEWLSITNGLKRDPSDGDATYSRNDLKILVKRLTDYATSLEWRTQGEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPN9</accession>
    <name>A0ABQ8VPN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_819831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="186" mass="21262" checksum="D1A9F63415275139" modified="2025-10-08" version="1">MAPLEFQHIERQSHSKFALVEKNDDGDKIVFSAQQVRLYVYFDKNLRRMQKRIGYTPIGYHSFASEFNKEDLPYKFAYWDHASFHEPTITNLNTQSPPMSIFGIEEWECFAPNKAVRPGYKEVLSTEYGELCSMALDQARGATRGRRKAEVRKQEKKNAAAAAEHKKTGTLHFHSGPKNAGSSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ44</accession>
    <name>A0ABQ8VQ44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_895050</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14829">
        <property type="entry name" value="Zeta-COP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="8"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4496720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="188" mass="21026" checksum="C2CED42D408A8165" modified="2025-10-08" version="1">MNLSLYSISAFLILDAEGHRVLAKYYRPKSHPNALNGEMKELATLKEQKAFEKGLWGKTKKVGGDIILYDGYLAVYKHSLDIIIYFLASPGENELMLSAALNSLIDAQSLLLRNQLEKRGVLENLDVVLLCLDETVDDGIILDTDAAAIASRVSRSRPDTTDITINEQTIMNAYQTVKDRVAQRIREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQA4</accession>
    <name>A0ABQ8VQA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_916493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="3">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="39542" checksum="654DF363ED6C194C" modified="2025-10-08" version="1">MSEPLTTAEIQIQVNWNHYLELIEFVILAYDYLLTFDLEIERFWKRDTKRLAAILFFVNRYLTLLGNVPFVLLFFRPGLILRYGDVRMDDPFSSVHSLIDNRWRLWSFYTGVIDRREALDLYAQILIYVVQINISILFLLRMHAIYGGSKRIAGFLGVVLIADIKSSPIGVSASGYYSEFLRYAVSVSVATTIESDWTGIDVEDFVHLAYLWIGIFVFDLCVFSLTLWKTYCIYKDGYMMSRGIGTVVMRDGLMYFGIITLATLANILAFAFGTEFTKGLLPIFSNIISSVMMSRLMLNLREGHTNETQMSGLIFANNELSMAPQASGPYEHELSHRQSRTNSSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQF3</accession>
    <name>A0ABQ8VQF3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_864715</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="52440" checksum="66CFAEB3A7090B28" modified="2025-10-08" version="1">MSEIHNYDVLIVGAGFAGVHQLLNVRKLGLTVKILEAGHGLAGTWYWNRYPGKDVYHKHCLCVPVLTLQCQFSDPEIWQGWTFTEKYPDGREIQAYFQYVDKKFDISRDVLFNSRVVSAHWDDSADRWNLTTEDGEVFRGQFLSLCTGIGSKYYIPEFKGLNTFKGEMHHTARWPETHDYKGKRIGVIGTGATGVQVIQEIAPVVAHLNLTGLHFDINPKLMFDATPEERTLFFEEHWEKGGFHFWMGSYADLLLNPKANNEAYAFWRKKSYYEVYSQPNVRLVDVNKTAIEEITPKGLKTSDGVEHELDVLILATGFDMDGIPIKEKWADGVQSYLGVASATYPNMFWIYGPQSPSSFSNGPSTIMSSELTSDWIIQCIKHMKENNISSIVPTEEAQHAYSELVDQPGAAALWSEAKTSWYMGKNIEGKKAQMLQFSGGIPAYAKLCNDSAAAGYRGFHLKVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRA4</accession>
    <name>A0ABQ8VRA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_877303</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017126">
        <property type="entry name" value="Condensin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="201"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="481"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="532"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="643"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="643"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4498918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="814" mass="89954" checksum="9909A7EF4111F4CD" modified="2025-10-08" version="1">MARSADQSRPLYDDSDPDTEPETFKPQRNGTRKRLSEAYNPDNDASFASDSGVRAQKSSVDINDDAAEKRRRRKSTKIAVHENAHAGPSSEGNDEVDKSRTIKQKQQLTTVAPLAPPEKESIDILSSKFEEWMKLTTDNKITAANTWEFALIDYFHEMSLLRNTDDNTINFQRASCTLDGCVKIWTSRVDSVGTETAKLASNLASGGNMDEDEEAGSDDPDREQTKQKKKRASRRENNLSDASQLRNKKPDLEFSVDPLFRKTCADFDEGGAQGLLMNHLSLGVGQDGSLRVVFDASDSISKEDEDDLHEPEDLIDLTQLRAEFIPDLDGLQSKAISQELSNFSFTQNPLINDDTTFFQDDTIADGFDDDDDDGFEAMMVDGAPPVEDFFVGDDAVGDDYGVGMVDGDDLGDANSNGSVGPMDNGQGGSGQFVPFDPRHAPNQRDLMLAMNTEDGGGMMDYFDNTFLQNWAGPEHWKMRKPIRRPDTDTAPKVAKPRKEKKEPNRIDFLTPSDPGKSWKIIADELFAPPSKGASINLPGTSAAAKKRKAKDEKKRDNHCLPDDMHFSSRQLVTLFLKPKFSLKMRGQRAPAPTNAEGEVDENFWAQAAADQAAGRSGGDDMDDTGAGDAIPFNTQFFHDDYDDGPGFDDAYDGDGGDGGAIDPGEQDLLAATQGQTRRVKPEAVRFTKRAKRVDVRKLKENIWKGLDIVVPPPKNADDERMDVDEDEPLLTSPTEARQFTSVISNLQRSYPRDKMEEISTSFCFICLLHLANEQGLKLENSATSSLDSDGSTDTKIGNIWDLKVYRDPEAAQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRJ4</accession>
    <name>A0ABQ8VRJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_979896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="331" mass="37816" checksum="9968C2CC62E71CFF" modified="2025-10-08" version="1">MKKFAHDFSLAELDREGSLASLLRISRLDDSESLTSSLEPGGMMDALPQLLETLHRLQVIPSPTIPNLYDSHSPKCPSNKRKRTSVSQSSTEKVQQWQACQDQVVPEEQEDTAAEVEIQNKRSRSMAPPPPSTNMIEHHQLGPDVSPDQVPVRPSQKHVRVVLRKLKDFPNSRIRVKNQLEETKEMLNIVESVHQQTDGKLTEMRWTRYIIEEDVLRHQKKDRTLVDGTTKLGSKSLQAREWKNWIQENTITQKLHQASVEVPENLAGASSLAREPIPINAIAYRSEGKGWGYWKNMYGPRADDEECQEGVEEEEEGEDEKEEYSESEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS10</accession>
    <name>A0ABQ8VS10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_916512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="348"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="55704" checksum="5B005C84F3D80A60" modified="2025-10-08" version="1">MTASSLSPPDVQSEETQKNSLVGAAVHNPAPETSTKEVDSQQVLDQLTVTERPESSGEEASTPLEADNKSSEQPRSSSPVPSATLAAKDVSSAPEVKSTEKPVEKAEDGSSSPTTPNGSHRRKAQMSSTSETVAPPESPKTKSARPKPPFLSRLLRVLIPCIPSSPHSQPIEIDEPKTAPVSTLEKPKPLKEVPEVTSASESSPSKATPNASTSEPNIPLPLSITPPVAITPTIQDGDVILPPTPTNQLLPQAETEGMTSGAVVPPGSSGTVDSKRSSHYSTSRTNGAADGEDSDGTSSFTDDDELEDVHNLDDFEDEEDRLISNGGAGIPVGPDGIPRPLLPPIAPQHAGRKCLVLDLDETLVHSSFKSIPQADYVVPVEIEYTWHNVYVIKRPGVDNFLKKMGELYEIVVFTASLSKYADPVLDRLDVGHTITHRLFRESCYNHKGNYVKDLSQLGRPIADTIILDNSPASYIFHPNNAVPVSSWFNDPHDTELTDLVPFLGDIGEVDDVRGVLDGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSC5</accession>
    <name>A0ABQ8VSC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_815076</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4499278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="515" mass="57965" checksum="A3C2E852059A40AA" modified="2025-10-08" version="1">MISLLLYPALVLGAATTYLFCRFVEHIVSTDLALQHVPGPRPSSFIWGEEWLLYHSTPGSYYVRWHQQYGKVLRFTGAFGHQVLSITDPRAIKYILSEAVFEFPKPKGVRAWFKATLGEGILWVEGKEAHERQRRALAPALSQRSVRNLVPIFYDTSAKLAAQWMKVIDNSRSDEAEIEVTKWAGRFALDTVGCAAFSYDFDCLSGGPHALAESMDGLTNNENKTSSFYMRALFWIFPAILSIGDKGEMIRKSKLELGNIASKMWRDAKVAGDLNGKNLMSIILRNEAKFPTHKMNEEELVAQMRTTISAAFEPVSAIIAWTLYELALNVRLQNELREEVLAAGLGDPSYDDLTSNLLLLDAVLREVLRLHPPILENHHEAAETISVPLSEPIAGTSDAYLVIPKGTILEIPVNVVQTDPDVWGSDAEIFRPERWFERKKQGLRHEREILAFSEGPRSCIGKNFALCEIKSLIITLLRQFSFTCPYEIEAFQSFVIRPRIKGQGPSSLPLIVRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSP0</accession>
    <name>A0ABQ8VSP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_864457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045946859" evidence="3">
        <location>
            <begin position="27"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="333" mass="35690" checksum="46BE225400E8143A" modified="2025-10-08" version="1">MVVYFSSVDLPSLFLLFAAIPHVVFALNNVTISHTSSSIDYKPNSSVWLSSDSTLDYSESHTTTTTKGASASFTFTGVAIYYAAASWPYPVSANISLDGGSGTFVDLHDYQSAQTNGGSASASATIHWFQTGLSNTSHTIVVSLAKNATYAVLDTFIYTIDDGDSDAPDDGHTIWPIILGCVLGGLVLIGAIIGLVFVYRRRQKKNGKPIWDTPVLDNLMTPLVATQASEIHPLVASDFRDPHANNPSSPSGIRSQTLDSSFSTDSLQDGKYFDYVSAPQLQFVEGSSRSGVGSTVVTAYPDEKVIKSDVILGVANPETEELPPPAYSEHHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSX2</accession>
    <name>A0ABQ8VSX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_814159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="423"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="55191" checksum="306329A026A64813" modified="2025-10-08" version="1">MESHRSSEQPFDDLYSYSDQPFMSSSYESFDPTHPSLQTSHSPTVDNFHHDSTSQQHTRHFVFHQEKFESNSFAQFLKEDDERFFATFPEAAKAAAQQQQQQWLVLGRDYRDFNGSAAFNLSANHGTYAYPSPTSPVHPSNVVDVMERGQGTYPAPYATSASSSHASFPYTLDPNSCNDVPLEGYNQLSESLSARQGVVTPVSNFANSSFYPPLSSEVHPNIHGLQHDSIMPLSLPSPISAHASGQSPQLLRLQSPTMNFLRSPSEITETLFSPLESHHSQMYSLSPEAILAHSPASPSPTLLPRLPSTLSPVSMVTPPEQLTLPPVPQDPLSDSEPLADDSNGASSSKTVLTKPSVRRKRRRNLSEELQSSNSSKSGSTRSYVYGKIPLPKPTPPPAPKASKSRPAASSSSSQNEKKSLALACFFCRGRKIACGPQDPNSADRTCNQCHRRSLKCEYPTESRRGMRKRKSVVLNSSFRADKEFQSHTPKLAISSTSSSSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTM0</accession>
    <name>A0ABQ8VTM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ser/Thr protein phosphatase 2A regulatory subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_788925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="86"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="202"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="241"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="273"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="280"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="319"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="358"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase 2A Regulatory Subunit A helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="397"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="514"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="558"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="588" mass="65586" checksum="FAB7177458AA375A" modified="2025-10-08" version="1">MDSDDIAPIAILMDELRSEDVQLRLNAIHSIPTIALALGPDRARDELVPFLQDSIDDEDEVLLALAEELGRNFEQYIGGSEYAHLLLAPLENLSSVEETLVRDKAAESITKIAAVLSNAQIEEYCIPLLKRLSGAEWFTSRTSSAALYPAVYDRVPTAIQDDLRKGYAALGSDDTPMVRRAAAKWLGPLLLKFSDPHILSDALPIYRRLESDDQDSVRLLTVEDLIAIAGKLKQSEIKEQLLKQIRHSISDKSWRVRYMAATHFNELAKAVGKEITREELIGQYVQLLKDNEAEVRTAASSQIPGFSELLEKEVILARIVPCVRDLSQDSSQHVRAALAMQISGLAPLLGRESTIEHLLPLFLQLLKDDFPEVRLNIISKLEIVNNVIGIELLSENLLPAIVELAEDKSWRVRQAIIEYIPPLAKQLGKPFFDEQLGNLCMSWLGDTVYSIREAAIVNLKNLTDVFGVDWSRSAIVPKVMGMGQHPNYLFRMTTVQAITIIMPSLNLDIVRSEIIESLLQLASDPIPNIRFNVAKSLEVLLSAYGNTSEGEAFVQQRILPVLEQQKNDQDADVRYFAARALQKVAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTU2</accession>
    <name>A0ABQ8VTU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alanine--glyoxylate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_104976</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF24">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="9">
        <location>
            <begin position="58"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="439" mass="47376" checksum="6A58876DF764DBBB" modified="2025-10-08" version="1">MSLLLSVSQIRGPILTQLRSSTSIFTRKMSSIEQFKQSPHKLLVIPGPIEVSDEVLFANAHPSMSHVSPDFIPVLGDCIRMTRTVVDTAKGQPFLIAGSGTLGWDQIAANLVEPGENALVLHSGYFGDSFAECLETYGANVDQLKAEIGAAVSQEAIAEALGKKKYKLLTFTHVDTSTAVLSDAKAIVETVRRVSPETLVALDGVCSVASEEIHMDQWDVDVIITASQKGLGTPPGLSILVASVRAMQVFSSRKSRPTSYYGSWKKWLPVMQAYESGKPSYFATPPVNLIYAFHASLSKITKSSPSLAERYELHRDASRKVKAAAQELGLKQLPLDPAFAANGMTALWYPDGLSAGDILPRLVKKGIVVAGGLHVDVKDKYFRIGHMGITAVEKSRGDVDAVVKALGETLAEAAAEKLKQANLRFGPLKDNGLMMKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU47</accession>
    <name>A0ABQ8VU47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_812411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="51520" checksum="069E0B8A1F148689" modified="2025-10-08" version="1">MLMSPASISNILGFDFSVFELDVSATGDILVDEPTVLSERLVAVFSNMARLQTFRLMNSAECGPWPALLKAILTTPSLTTCEILDSPWRRPEEKFSRLMLDLPRESSRLRKFVYRVPFTDCFPRESESYGRRDKVQGLVELSNLSVIVSLVCDSVEALEIPAELALHLADLPYPKLSELTFRGHEPLHTTDWSMMFHRAPRLRDVHIQTPAYFNDRLISPIISTCSIPHDDPVMRGMSNLQSLTISNPLGKNLFFQVLTYANLRTLSLKAFPLPDIIGARWSNVHSRVLTGSEVLYILNAVQIVSLSTFELSYWVDASDVALLSRIHISFPKLSTLEIHRFRPLAKENSENDPLSSMPNTLAKAVNLEHLMMNLDFPERPRHNDWRHDDSERSRTFYSFLEKEIVSTFAHAVPSLKTLGILSHHSFSSCWDIWKVTKTRGLIPQLQTPIYPPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVW1</accession>
    <name>A0ABQ8VVW1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_815406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF561">
        <property type="entry name" value="PROTEIN TYROSINE PHOSPHATASE 36E, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="6">
        <location>
            <begin position="74"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="700"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="941"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="316"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="458"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="539"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="667"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1177"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1350"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1552"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="547"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="587"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="686"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1089"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1196"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1418"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1553"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1564"/>
            <end position="1579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1625" mass="176884" checksum="2796C3489848E280" modified="2025-10-08" version="1">MDQDFFGTRPDAGSLGDDVDTFARAISERSILNPVMSAKDLSPIKSKLPLSTTNSKPSSSFSSVEPVQLLPFINNPSALIIDIRPHAAYSSARIPTALSLSVPSTLLKRPLFSLDRLGAMLPSSSARARFAEWPKFTTIVVYDVDSIGSPFLPEGNNILGLLRKFSNDAAYNGSALFWLKGGFQRVWRERRDLVDFRPPEPEPEDDANDSGSLKTNHLPPKAFGSGTTTRSSLDQSSPRKRPPSAMSLRANAPLMSEKTSGTSSVPFNPFFDTIRQNFELTQGITERIPLRLPKRVRKRIDELPFEWLREISRRSDVKPDDSFTSDSDESPSSTSENKSIATNHPSPESSGKLLPPGIHYERPTSPNKMSKQHPTPPPPNQALLDEGMESLAIQFYRIELAEQRRLMGVMKHHSAESGVVSSQTQAHRKDIVESADSSGLRPHVPQTVDYMSAHVSLRSVSPSPQSGHMRESFGVLNSNKPRNVSSGHTVPPSISESDSDHGRDSKTVFPYSITAGVEKGAKNRYRHIWPFEHARVRLHARRHSPSRKSAQSANSSQSHASSQPSASTVSPPSSALSIRHSGALTGPITSLSGSPTSGASVSRSVSDATKSPRSSNRMNRHGVKPSFGTGGLGGLSSPSFTFPSSSLTAPVIFNGASVIGGSALKPSFTHMRAPPPAAGSGGETTESEHEHDDSEKEPTSEDHDDYVNASYVQPLCTTRRYIATQGPLEATFVDFWTLVYQQNVHVIIMLTREIEGSMVKCGPYWKDEVFGPLRLKLMSVEGNVDEGKDDDVRRKAGGGDPAVGGFFFSSSVIPDTKHGKKKKKNPADATIKRTFLLSHVGYPDIPPRKIVQFQYLEWPDMNVPDDPRGVLGLIKEVDQAVTEAMHLNGQGEEEEDTTKEVLPSNIETGVSAFIRPSLSRSKSGLGETLNPNTGIANKAMGRKHSPVLLHCSAGVGRTGGFIMVDAILDGIRREFRKKKNLCLNHEAHNVNNVSWNTPATMDVDVKNEETAVQDAQGYWNRNGNRNVDIASNKTDLRTVAIPAHNNGNILIPPGQKSNNDLLTPIALFPTSYDSQDNYGNSTSNSSTNPLFTSPQTPMQVDGDPYISSTTDNREEDEKETIFPHQSFTTRMWAEDVSDQTGSHGTAFRVDEAVRHMHSQSRLSEWDVSNARLKTQIEENNERASSVDPRSMDVNISGSSQPTSSGPGQHIATTPGVNIGLQSGVAAVVARGRPGSIPFVFPSSSIDSASSSDDSYDLKNGSKSMPHHLLGHHALNSLSYDSAMPKASTLPVIGEGRVPVLNVRGEEARLRTWSAPSARRVQTVAKSDIERTSKTDNSESQVLRDAFTFTSSPSVLGDRSRAVEKSPSPFSRIRGIDLDESASLPPPSRSLSPPNRTDVPSSAPPNPQSSDKSEGSMVADSSPTPATKANSLSTDPALRSVPVGTVNESANASVYSQGFHTWNVDHSPFVKDASSADLSYPRALHHDNSPQALSNLGEPLLEVLQDMREQRMSLCQSLRQYVFVHAAVIEGALMIVDEERERERKIMRMDVDDTSSMKQAVSPITGTTSSSSRHSWTTTTGKRVASPTELPKEDKKGDQMLFKKPSIKKKLILSNRSPGILVNEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVZ6</accession>
    <name>A0ABQ8VVZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_863121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047088162" evidence="2">
        <location>
            <begin position="18"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="173" mass="18711" checksum="7E231891D9C08931" modified="2025-10-08" version="1">MHFTCYIILGLVSAAYAVPLSTVYNNMEGASDQRSLSFQARGSLPYGKLISRTEETEPILAKQVSHTSSNSDANDDHEPIDANNPRPEVSEAKHLTLGFVGESNPGTQKNGMSPDAAGPSQTKSTRFGLRTKLEALKNRIAKSSLMRPEDRSKFILHDVGKDPISKGKGGTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW28</accession>
    <name>A0ABQ8VW28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_430416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20180">
        <property type="entry name" value="UQCC2_CBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="106" mass="11941" checksum="10A9406512009A85" modified="2025-10-08" version="1">MATKGATKLSQQLSSVAAQWPKDPFRPHLLLPTFLQSLSKHPKLTPEAVQAAQALKNGQAKKQFPLPKEILKPASYPMHYDRLVEGLHKSAQGIGRPWWKVFFGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWP2</accession>
    <name>A0ABQ8VWP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_862913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="50368" checksum="6E152B503C5804CB" modified="2025-10-08" version="1">MPVVLPLELHELIIDRLFYSFLELKACSIVCKAWLPRCRLHLFRTLIVRPRIFNKGYSEPFCCEYQQFFTLDHSFITPSIVFHVRRLKLSYEVQSPFGLLPDSSCAPISSALIPVSSMITIPFPFKRLQTLHICWRSVNWGGVTALEKMLQQIDCLRHLVIEGRWRFRVKEDILSSIAIYAPGLKTLCLAKLQWFPNSIASPFVEEILSRWNDRFYKQGVPPLRLEKLCITKGTSKNCVADLEKVILSSPCLDLSNLRYLAMPAGSLQEVIHDARFRTIGKQVTHLAIVNLDTSTFKVDSDSFPVLSHLQLYIRKEHDLVRFLHVHGASATSTPPWVDMHINFEKHLNHRLQNREMTAQSYSDIIVHTSSVDLALRKFIVDCEVSMQISVHFAHLDGGEPDIQHDYIREMFPQSFPTGHLEWTDRKSLEWWFDHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY00</accession>
    <name>A0ABQ8VY00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="41401" checksum="541E1E469045C14F" modified="2025-10-08" version="1">MDHDQAFFTLPQHMQRRIDAAFLSAIKHARSLEVTTSGHSDLDSAEPPLKRRKISTHTELFVDSRGGFIVDSPKNGQGGGGFILNDTDVAGNGDGEGGGGFITDVNMSNAPAVDDSSQIPLSCIPTALQLLDLPPDDEQVLAIFRNAASGWDNHDGSRSDDNLEVTRADWRAVCTILLEPGVGDDGMADGRRRQSGSPGGDAEYVEENAEDDVDMQYDDEPESDDDYEPGPSSATSFKSRSTRRHTPATNKVHVAGSKRRTRGSRFRTAETDSDAGEDTDGEDTDDDQEGTDSRTRRLTVRQKATCLETFRLFFPDAKDDLPTRRILLADIQRVAKLLGEKLKAEEMLEMLEVFSTAPDKSMDLQDFERMMIEAKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY01</accession>
    <name>A0ABQ8VY01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LCCL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_194700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24352" checksum="4D91F838CAE5291A" modified="2025-10-08" version="1">MKYSDSEGYLNAPLYFHFESFSLHRVSMAVPTNMSILNISGKFASNKSLSDNEASDDILRLQGMGWVKRKIIGAGTLTLAIEHFKNAEGVECINIEQTLNPGGLKTNDERVLDWMEKPKEDSVFGATIGQNRRVKAEEIEDEYLSKGWTADTLEHGLIQSRVVSDTAKSGVSWTVNQTWGIEEVNSERRYVRHMYMKGPKGEEVRGRLVYNYVGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY25</accession>
    <name>A0ABQ8VY25_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate esterase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_749182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127078" evidence="2">
        <location>
            <begin position="20"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="313" mass="34487" checksum="929CB8BA2A8D7772" modified="2025-10-08" version="1">MNLLRSALATLILLVTVQATGVAPGQIKNFVTFGDSYTDIVSVGDGGTAWPVYASGYANISLFPFAKSGATCSNNLTDRPFPSVFESQLPTYFEETSNGSLKLKPEETIYTLWIGTNDLGESALLTGDDTASLVDVTTCMVNWVKVLYESGARNFIFQNINPLQHTILYSSTGYYTKFWTFPRNATSWSVSMTELTLSGNDLTQLKLQALLPQIPDAHVAHFDSHSLFQDMFDNPSQYLNGTAPLNVTGCINSCVFQVNEPDSGVCTLVNGTDRDSYLWYDELHPSEQADRIVAREMALVMEGKSSKWATWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYR2</accession>
    <name>A0ABQ8VYR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">25S rRNA (uridine-N(3))-methyltransferase BMT5-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="89"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="345" mass="38047" checksum="79FE5F4A27385AF7" modified="2025-10-08" version="1">MGRSSKSLKNALSSQQSRLKGKEKASHAAQIAEQKARKLAGGPSASSRSKANQTTGQRNEIMRAPGKGKRTLPSTQKPTIPFQPTDTILLIGEGNFSFAHALARPSPSKAELAHLAHLPSQNITATAYDSEEDCYAKYPDAKDIVADLRGWGVEVLFSVDATKLEWNITFKGRRWSKIVWNFPHAGRGINDQDRNILSNQTLILGFLHSAAKFLKQGPVPSVAGRKKQKASDVDEDEGEETDNDTRDSLESGSCRGTILITLRNVPPYTLWDVPKLAKNPPSLAQGSTSSNPRYIILRSFAFHREIWDGYEHRMTKGLRAHGTGKTGEGGEDRTWEFCLRDIPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ45</accession>
    <name>A0ABQ8VZ45_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc finger Mcm10/DnaG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_863075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MCM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="3">
        <location>
            <begin position="403"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="249"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="583"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="723"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="746" mass="81877" checksum="C41535BF1A9B5D53" modified="2025-10-08" version="1">MESVANQALKEKQKKEALRKQIALLQSQLSDEEDLAPASPKQKSTTQGVLVPRTPSPRKKRKLEELSAPPPRNILSAAASITNHTRTPAEQGECIIPPKPLPSKLVQRLSKLHSDEDDTSSKSVRRTSSFADKPPEPGSSKRDENLAIIQSLELGPTDHKPPFDDPHFERVEPNSGIRLKSRILPHEDLQDHLRGRYYLSPSRLYSSISLTPDKSGYDVPVDGDWITIAVVAERGPIKYTNPPVGIAKEEEADEDGAPSASQGKGKDNIVRKNKSKPSDAPNPRRRYVNVKLIDFGSRKSSSSESKGHILGDAFLTLLLFEAEAVDLITEEYGKKLAHPRKVYRGGSGGAFEAMAKLKEGDVIALLNPRIMKPFTSSSTSNPHPVHNILAVTPMNASSITHIGRSLDLGMCMVQKRDGSVCGSWCDKRISNVCEWHVTNAVQRRRAARSEFAVGTSGMTNSAAVKSRFNSSSSDYDPVRKTGLLPRGGAAATQSKHKFGGSTSYAPEATYVLSGHVINNSNTVDTAHVSEQMGREGQARAQRAEMRRQEDELLKKLLKKERAQGLDGGTGHMRSVLKAREVIERAKKEKDSKTKRQTIEKGEELNENRKRRCHKGDNSDDSDGDQTEEDQTTRKPNASRYRPEMIKTLGFDPVAMKLGPQRQSNADVQRKLADLATLQNSRKEVNLGPRPGPKIRSGVFKPAIEPARFKAALHTGMMSTDVEMAEQSNDPGAGGEGMVDLDSSDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZI0</accession>
    <name>A0ABQ8VZI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NUC071 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_749410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
        <property type="entry name" value="MPN_PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.40">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012591">
        <property type="entry name" value="PRO8NT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012592">
        <property type="entry name" value="PROCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012984">
        <property type="entry name" value="PROCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021983">
        <property type="entry name" value="PRP8_domainIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043173">
        <property type="entry name" value="Prp8_domainIV_fingers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043172">
        <property type="entry name" value="Prp8_domainIV_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019581">
        <property type="entry name" value="Prp8_U5-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042516">
        <property type="entry name" value="Prp8_U5-snRNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019580">
        <property type="entry name" value="Prp8_U6-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019582">
        <property type="entry name" value="RRM_spliceosomal_PrP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08084">
        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10598">
        <property type="entry name" value="RRM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10597">
        <property type="entry name" value="U5_2-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10596">
        <property type="entry name" value="U6-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="2079"/>
            <end position="2210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2311" mass="267763" checksum="22C4E22919234131" modified="2025-10-08" version="1">MQKKRYGEKRRGGYVDMGKQDLPPEHVRKIIKDHGDMSNRKFRNDKRVHLGALKYVPHAVMKLLENIPYPWEQVREVPVLYHITGAITFVNEIPRVIEPVYHAQWSTMWLAMRREKRDRRHFKRMRFPPFDDEEPPLDYGDNVLDVEPLEAIQLELDTEEDAAIIDWFYDPKPLIDTPAVNGSSYKYWSLPLPVMANLYRLGRTLLSDQPDRNASYLFDKKSFFTAKALNVAIPGGPKFEPLYRDMDSFDEDWNEFNDINKVIIRQQIRTEYKVAFPHLYNSLPRSVRISPYHTPKNVYIRTDDPDLPAFYFDPLINPISNRGTTPKNMPLVSHEDSIFGPNSAEDDEFELPEDITPFLEDKDLENDLTADGIALWWAPEPYSRRSGRMRRAQDIPLVKNWYLEHCPPNMAVKVRVSYQKLLKCYVLNELRTRPEKAMAKKNLFRQLKATKFFQTTKLDWVEAGLQVCRQGYNMLNLLIHRKNLNYLHLDYNMNLKPVKTLTTKERKKSRFGNAFHLCREILRLTKLVVDAHVQFRLGNVDAFQLADALQYIFAHIGALTGMYRYKYKLMRQVRMTKDLKHLIYYRFNTGPVGKGPGNGFWAPGWRVWLFFMRGIVPLLEQWLGNLLARQFEGRNSKGVAKTITKQRVESYYDLELRAAVMHDILDMMPESIKQNKSKTILQHLSEAWRCWKANIPWKVPGMPTAIENIILRYIKSKADWWCSVAHYNRERIRRGATVDKAVVKKNLGRLTRLYLKAEQERQHGYLKDGPYISAEEAVAIYTATVHWLESRKFAPIPFPPLSYKHDTKLLVLALEKLKEAYSVKGRLNQSQREELALIEQAYDNPHECLSRIKRLLLTQRAFKESGIEFFDTYDKLIPCYDIEPIEKITDAYLDQFLFFEADKRGLFPAWIKPADTEPPPLLVYKWCQGINNLTDIWETSEGECNVMMETVLSKVYEKVDLTLLNRLLRLILDHNLADYITAKNNTVLTYKDMAHTNAFGLIRGLQFSAFVFQYYGLVLDLLILGLQRASEMAGPPQMPNNFLQYRDSATETRHPIRLYSRYVDRLHILFRFTADESRDLIQRYLSANPDPTNNNVIGYNNKRCWPRDCRMRLIKHDVNLGRAVFWNVKQSLPRSLTTIEWEDTFVSVYSKDNPQLLFSMCGFEVRILPKIRTMSGEQFSLKDAVWNLTNEQTKERTAQAFLRVSDDGVQQFNNRIRQVLMSSGSTTFSKIVNKWNTALIGLMTYYREAVIHTNELLDSLVKAENKIQTRVKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVAVTHFRAGMSHEEDQLIPNLYRYLQPWEAEFLDSARVWSEYSMKRKEANAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDRGWRVRTDWKQYQLLKHNPFWWTSQRHDGKLWQLNNYRVDVIAALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMRYKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESVVMDLCQVFDQELEPLQIETVQKETIHPRKSYKMNSSCADILLFSAYKWNISRPSLVTDVKDVLDGTTSNKYWIDVQLRWGDFDTHDIERYTRAKFLDYVSDSMSIYPSPTGVMIGMDLAYNLWSAYGNWFPGMKPLIQQAMAKIMKANPACHVLRERIRKGLQLYSSEPTEPYLNSQNYSELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRSGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALVRSLPVEEQPKQVIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACMKMEKFGDLILRATQPQMVLFSLYVPDDWLKSISSYTAFSRLILLLRGLHVNNEKAKVILHPDKNTITEPHFVWPTLSDEEWIKVEVAMKDLILADFGKRNSVNIASLTVSEIRDIILGQEIAAPSVQRQQMAELEKSSEAQAQVTAIQTQTTNVHGDTIQTVTTTNYEQQVFSSKSDWRVRAISATHLPLRLQHIYVSNDDVKDDAASYTYVLPKNVLRAFITASDLRTQVAAFLYGVSPPDNKQVKEIKAIVWVPQRGSNNSVELPSQLPKDDFLLKDLEPLGWIKTQALEIPHLSPTDITTQAKIMADHPEWTSSSICITASFTPGSVSLSAHSLSVAGFEWGRKNADNSANPPGFNPNMSERVQLLLSDRILAMTLVPEGRVWNYGIGLTQLWTSNISYSTILDTPLPFWAEEHRPNTFLTFANLEQGEDSADVENSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W029</accession>
    <name>A0ABQ8W029_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Member of major facilitator superfamily multidrug-resistance, DHA1 sub-family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_806381</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="67"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="57044" checksum="32D94A9DFB428AB1" modified="2025-10-08" version="1">MTRRTPKSDGIHGIDCLPSFPINGTSAGRTEYSFPSLFYMSPQVDEETPLLQVQQDKPQRTPLPWFQFTIVLFLQLAEPLTSQVIYPFLPQLIRDIGITRGDETKVGHYVGLLQSLFFLTQAMTVLHWSRISDRIGRKPVILIGLFGLSMSMYCFGLATTFWGLVLSRSLNGALNGNIGVIKSIMAEMTDATNIAQAYAYMPIAWSTGGVLGPMIGGALARPAEQFPHLFGHNEFLKKYPYFLPCAVPATFSAIAWLVTFLFLEETVQAPAFALPKIFRFKTNNTGKLMISAPEINDVTTEIPDNAKPVPFRKLLNRRVLIAAGNYATLSLVDITFRAIQPLFFSTPVELGGLGLPPSSIGNLLSIFGLLNGVMQVFFFAKLHDYFGSKKTFIMGIASTFPIFACFPILTYLVKSNGGVTPLAWVFVLLQIIFSLSISFSYGAIFIYISAASPNRASLGATNGLSQMTVSICRAIGPAASNSLFSLSMKHHYLGGFLVYYVLFTIAALALVAATLLPRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1F1</accession>
    <name>A0ABQ8W1F1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_976778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="87" mass="10102" checksum="8A36176049702C5B" modified="2025-10-08" version="1">MFTNKLAKNKRMHPYAHALRRQKEYLNEVALANTLPPPQNTDIDRGRIEEKIDRPLDQALIVFLVVSAVVRILNYYILNKIISSLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1L3</accession>
    <name>A0ABQ8W1L3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="193" mass="21628" checksum="104D81DB12EDE078" modified="2025-10-08" version="1">MTEGIGFQSNFSCNHSVVLPHSISEVFTTIGTTQGHERVCRLSKLCTNFELLNSDTVSLPTKAALSDSHVRTLPTSDSRTAEAQNASEDTRTLPRQAFTMTETIPLLFGLFKNDVILNGTLTWDESANLALYETESDNGVQVWKLRTFEEVDANSTRVSERIEGVCPRWLKPIVQREASKGHIAHMNEYYTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2W8</accession>
    <name>A0ABQ8W2W8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_862302</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF75">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_4G07050)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="439" mass="48392" checksum="9A2704D31AA3D772" modified="2025-10-08" version="1">MDPTNKAKGPSPHYSLYQREIFRQGGTEGKLPHFSVHPDELVESTKKKLSDRAYFYANSNAGLGWTDRANREAFYSWRIIPRMLVDTNVRDLSVELFGHRIPAPILFAPIGINKLYSPEGELIPAKIAGELGLPYCLSTAASSSIEDVAAANDSGASSIASDGGNYCQVRAGSNAQSPRFFQLYMGHDDDVTMSLLERAWKSGFDVCMLTVDTWQLGWRPTDINLANYVFYYPPGTTGNELGASDPVFMRKYGDELKNDSGKWIDSSVWHGKAHTWEKMPWLIKQWKRISGGRPFVIKGIQSAEDALKAYEIGCEGIVVTNHAGRQVDGAVGSLEVLPEIVDAVGDKMKIIFDSGIRTGSDVFKALALGAHAVQVGRLYVWGMAHEGEAGCRHVMKSLLADLDITMTVAGYPSITRDVNRKALRRNESGVYPRGEHAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZUJ8</accession>
    <name>A0A9W8ZUJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ubiquitin-40S ribosomal protein S31 fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_527372</name>
        <name evidence="11" type="ORF">C8R41DRAFT_868937</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000046">
        <property type="protein sequence ID" value="KAJ4466095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZUJ8"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031386">
        <property type="term" value="F:protein tag activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000008">
        <property type="entry name" value="Ubiquitin-40S ribosomal protein S27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_eS31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038582">
        <property type="entry name" value="Ribosomal_eS31_euk-type_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001669">
        <property type="entry name" value="PRK00432.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01402">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4466095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4481839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="159" mass="18104" checksum="859AF9E2A8E7E9FB" modified="2023-11-08" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKTYNTPKKIKHKRKKVKMAILKYYKVDSDGKIKRLRRECPTAECGAGIFMAFHKDRQYCGKCGLTYTFTPGTKPPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVZ6</accession>
    <name>A0ABQ8UVZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_155743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000164">
        <property type="protein sequence ID" value="KAJ4463456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="525" mass="59589" checksum="92954A4FE8850748" modified="2025-10-08" version="1">MFPPMSSTHWLEIGFYSRFSLPPSMAKITLTRPTTTRRLSTWEVPLAKSAASNLACEAPAEEVFKVDSSAALCVQETRDVLAVNPFHEAELENSEYPLADSDSECDAEFKDVFYAYEPEFDASLDDDVLQSWTMSRNILAIDSTTPWLTPHIVITPASDTMSDLAIAWFNQPNYYQDTSKLCLPPSDFAENPSSLRSDAPPIITSSLAFHPISVFSPSRFNAMIEGCSHERLSYFNVVIALRRHIMKAVAIMASRAAHSFRERYDSALPFSNIDRPFSWNDPAEPILSASRFHRATLILDSTNPFRVPHIIINQPPPEDQWLTATNTVNDPQDYGFGRYLVVHSRGVNYINEPEDAYLSFPSDEYYDISRFDEKEEEENRDWADPVTENEEDYDGIRSYNDTLECYTSFEELPELDTESLTSVESPFAETPDPLDDDADYRSAYERDLEKRMVSSSVNISSVNPCVPLYIDGCPLDRSMVDALSVHDEDESSPYSWADEEDDLPPLEDEWYQSVIRRTQDVLADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW63</accession>
    <name>A0ABQ8UW63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_927319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000157">
        <property type="protein sequence ID" value="KAJ4463614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046027217" evidence="2">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="146" mass="16110" checksum="4487B5CEB4BFF975" modified="2025-10-08" version="1">MEFSLLSVSLSLFLSILVYGFDDRLHDLIYAFTSRLSNPKLTSPTPPRAPPLLPKLRDLDLGNIEAASYIELRTASPLQPPTLEDVHPRSQSPGTYPPGHISSQELRPSIRNSNTTYLILCGRSSKYNSYHAILLGSVHPSSLPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYF6</accession>
    <name>A0ABQ8UYF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_857484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="339" mass="37698" checksum="CD2D5471F8101CC1" modified="2025-10-08" version="1">MSLSKSTPRPGPLCEWPLDRFLPSSSNSTQGKLNGNSRPNKRPLSPGGPSLFSPTKKRILTQEGIFYPEKTMKSPFRGRSTPGGSFSDLLRAPDSPAKKLEFGSAKPAPQLLSIPDSCEVTSFFSLPRPSTPVKATLNSRSLATSPDLVPKTNVNSTPRHGFDDDDFFSTPERLLSSLARPPPPAPFTFLSRELPPPSDPQSIHHPGFVVHRDAHIVVLNPTVVESLVKDCKERDEWKENLVPRKKLKKVDIDSVDGKPMLMTPEAKKLEMEQMFKAKSTPATPRKTAAKEWHEDTSPTPRRTGLRFKAGTPAISEEEKRQRRRMLKDEVEADGMDEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYT6</accession>
    <name>A0ABQ8UYT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_783779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000161">
        <property type="protein sequence ID" value="KAJ4463524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="146" mass="16879" checksum="B2D2483108390DCE" modified="2025-10-08" version="1">MGYYQDGLRHDMTDISQYYRQDHEKDGYPIRRFWVAEIPSLTSDSGYEVVGCVALGKSDGPLFGELKRLFVLPAHRKRGIGTKLMRTVIVYAKEQKIALLQLETTNFQPVAREMYSRLGWHHNSTRESDFQAGGMRMSFVEYLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZK8</accession>
    <name>A0ABQ8UZK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phophatidylserine decarboxylase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_898486</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000125">
        <property type="protein sequence ID" value="KAJ4465583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022237">
        <property type="entry name" value="PsiD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF9">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G01730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12588">
        <property type="entry name" value="PSDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-tryptophan decarboxylase PsiD-like" evidence="3">
        <location>
            <begin position="51"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4465583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="410" mass="45667" checksum="CDA8E93CD2777D3D" modified="2025-10-08" version="1">MPPQYQRPLPSKQTILTRYGGWLPAKPEVYEAFFDDLLRTYDPKRPGAHVPAVQEFEDAIISSSKIGLLNLFENAFIQSAPENRIRDFQQLLHCMDKIVVAAPKFQVSRNEQGGITSGEPIGVPLYLLLDLLSNTAAGYDLFRNTRFNDALKALLDSWGKYLQSSKSNNTLSNSDEGWFSKLGLETLDNGRGIFNDIYECPDETAPQSDLPNFFIYNACESTVFHKATGVKEHDQFWLKGQPYSIYDMLATMQNDRVAQSFIGGTVYQAFLSPYDYHRWHSPVNGTIREIQIIPGTYYAALPDEGAEKSDPDFQPGDPRAATRAIIYIDADNEDVGCVVFIGAGMVEVSTCQVTVKVGGGVKVGDELGMFHFGGSTHALIFGPDVKLKFFDYVQPNEHLHVNIPLAAVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZW8</accession>
    <name>A0ABQ8UZW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_855506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000107">
        <property type="protein sequence ID" value="KAJ4467520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF16">
        <property type="entry name" value="RICH PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045753005" evidence="2">
        <location>
            <begin position="27"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="37564" checksum="C9434CD4A49F3AFE" modified="2025-10-08" version="1">MFSYKTSAFAALVGISLAVIPPVVRSATIDVTVGGPNGTVAYAPEYVNASIGDVVRFTFEQKNHTVTQSSFASPCSPLANGFDSGFVPVAANVTSDFITAELTIENTDPVWVYCRQTGHCEEGMVFAVNPGSDAKFAAFKDAAMGQNSTSTASASIVTVTATVTVSGGETITTTYGSYPGSSAPTAATSTDHKVIVGDNGTLTYNPANITAQIGDTVTFEFHQKNHTVTQSSFTDPCTALSASSPGTVSFDSGFMPVATNATTFPTVTIQINDTKPFWAYCRQSTPVSHCESGMVFSVNAVENSDSSFEAFQAKALALNTTASASGSASLSSPSATSTSNSALSIHGIYGAGTVIAIVGAAVGVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V005</accession>
    <name>A0ABQ8V005_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="136" mass="15358" checksum="6CB1FB06FC1C7D3A" modified="2025-10-08" version="1">MGIGTNQDEITLYLDSRYVSASEACWRLFHYELHQEKPNVVRLAVHNENGQYITFKPNDPRPVQDIAEAEGRKDSTLLGFFKVNKQEKCHASTIIHSPLNGDDQDSPSISHTPSPLRTDPRPYLPRSTPVPTQDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V038</accession>
    <name>A0ABQ8V038_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_871703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000118">
        <property type="protein sequence ID" value="KAJ4466074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="308"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="590" mass="65352" checksum="B03CE9A5E04C58B8" modified="2025-10-08" version="1">MSHNPEGALKLAMLITDWSNFAANNKSRARTTPLPTKSSGCVTPSISRPKYPAPRIRTDSSSDDEQLLPKKHKRVKKTLEPEPEPEQDDENESDTSEYVDELDADAEIEGEREDDAQASNYIQAEAVQFSHANSASRSGSGHSTQSVLPTLAGELEEDKQTVKKITRHQAPKLRTKLPQVRSHPHPITHTAAPTAVNQLPQVHSYPLRIAHTAALTTVNQLPQVRSRSLSVTHAATPTTVSQLNTAPAAPAWLECTNIHVVKKVRTFTLAKTGQPPVMLQIIDKSIAYGKLQMIFNHEYSPLHTFKIKQLAHACLMEIAERSGHDGRNNVCDRLERGDHDSYSIPLVTYVSRRIGNERADLKAHSSIILQAFGLVNNTGRLEAGVLARRRTYYYPEMPNGMPDYRKPFEHPVFASFLREAFFSSTYYSSIVRRNFHLFKSSISEKSEELEVTKGMVALAAAAIHACLHDCSMGMKSSFLAPELNGVWGLAIDILEGIESRNHSKYHRLMHKLFVEATGNSMMAQDGWCNQQHLDAVDWDAIENSDNDDDACVYPDPVGDSDNVASVHSGNTYHTEASTAPALAPISTPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0D3</accession>
    <name>A0ABQ8V0D3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MutL C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_702273</name>
        <name evidence="1" type="ORF">C8R41DRAFT_708388</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12298" checksum="E2D1899904299729" modified="2025-10-08" version="1" fragment="single">DDNPHVHRKLRLIAQPVSKSAVPDTRDLEELIKLLHNHPTGQMVRCSKVRAMFAMQASCMSSMIGMPLNRSQTSTILTHMGTIDQPWNCPHGRPMMRHLFDMTNLQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0E6</accession>
    <name>A0ABQ8V0E6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_70571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045166591" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7844" checksum="1F32BE4E511D5CAE" modified="2025-10-08" version="1">MIPQVSSALLLSYCSATWAQSRLDPYFAVVLQFAPKPHVLHDQKSYHFTECRIEPSEPLLTNGLARSAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0G3</accession>
    <name>A0ABQ8V0G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="517" mass="57444" checksum="550572B27AAA02B9" modified="2025-10-08" version="1">MSAISIENHPSSPGSLVATVSGNNDGSPHTPPDHPNKHAKHSPDASAHQTPHVSNQTDAGRKMPTQQLAETTGTRNRTMSTADSDMSLSEDEGRHNKGTSVNDPFMTNPRPHTRYNPRDRVLPELTLNPLDEEEEVIPSENTENPHGRLDYSGPESKTIRNLLNMTFLNDGQFQYAVFYPSDLLQGVSNPKIPMLLSGNDLWVAVVFFNGGNAMHQKIRTTIKDVEAFLTSIGCEFQQGQTISPFYDNPPEPTPNTNENPKRGRGAGRGGRGSRGRGRGATTGVEPKPNPRLKYTGPNTVFIRITSSDIQDTLLRIQTFALSRILAFHMVPIDINRRPSVVCLLYSTVLDNGEHTQQQILYSIKQKLRVNNPVFSALLAPHVRLPGSTKHKICTFVNSMDLVPAGYETERQGRTVQVWVLYAAPLASGSDYNKIDANEKAIGRYIASLRFEFINLEENTSIDSWGEQTECSLCKLTEHHFFMCPFKTEPWSGPMDHIDACIEQHPESLKQVKALTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0K4</accession>
    <name>A0ABQ8V0K4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="706"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="76853" checksum="D39103F45128B4D9" modified="2025-10-08" version="1">MTSSSTSSVAPASSSSSFDTDSGNSHRLAITGAVLGVFGIIGVGIILWWTLRMKPKVPYEEEAPSTPVPRSSPHTASGSGVADALRKSLTLNRSLSNDIGRSKSSNLNRNKSLAAKITPFNPDTTIEGDGPRFVHTPGANMRIATRLSNGVWQFSEPVRGALGQMHPLAAASQVSLLTQTQNLDRASSPSRPYSPYLTPTSNLSNPFSDANSYAPTRCESPAENPFDSEEIPDYGRAARRQDTSESHVSTTTSHYPFTRPSALTLRTQTQSMFRGTVYDLQSLSSPGSAVPAGIHDIDEDIMKHRGKPLPVADSELMRRGLRKESSLGATSLLGSASNLSLPMRQDSNDSYHGELGLGRRPSAASAVLLGGTGPVGTRNLTAINNGNRSTTYHPDLDDVIDVRGDSDEEREAEMDLADVAEEEDFQGAEALPTPVSGGVITGVSPYRMSEAFTSLEGHGLSSPGPPGSDRFPYAVSNHASHPSTSTIATSLYPHTITTKGGSSSLGFGLSNPYTSTSTVYLGSLGHLTRPSLDTERETGQDTNHSMRHGRPSLSIESAIDKKGRRMSRGSTLATTYEGFEGENTLVYESPISPGGSYPYSPTSTSYTHETRAQTKNWQRQSSFLGSESHGYGAGYGFKKPHHYQLGLDDVYAADASMSMSGHDHSREDGDGGDTTIHAVPPSWAIDGVSGVEIMDVPSVPPPTYLSPGSKSRSSSSTMEGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1E2</accession>
    <name>A0ABQ8V1E2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_853407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="945"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="789"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="873"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="962"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="983"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1028" mass="110556" checksum="47432290AEB180F2" modified="2025-10-08" version="1">MANYLPVLLYSVGSNAAPDDSSLSTLPRGQVDYLTHDWQEEDVWRSWRNMTRQKNEIANGVRLENASWRTWWKQRNKLKTVSPETLNWLKDSDVTWLYGPLHTAVEWTPPPKPKPDETEHKTASAHDRFDLSEPKHKSILKYRSISEMLTGDLPSPLFSPAESDNESDGNEELSREASDADASIHPTRPSLSQTKSDTHITRWGPNRAFRKDSPPRIEPTGAANVVPTSNTNASQSHTSPHHVYSATNLSGYFASHIQGQSQQAELSSSSSSPRGGSAEVTPSGGIHSNGHKKKHITFNTFVEQCIAIDQPKPKETTLAAILGDVEEDWYAKPHESVKATYDDGYDEDGEDGFDGDWGLNECAISTDSESDADQVLGESACDDDDEEEEEGMIQMRSRRDSFDNKNSARLRSTSKVSTSSSSSSASSASTSSNHKNIPPNIRRRRRSDGPKNVSLPRKGSISLARNSSSTALSSSDKEMVSIAPIAPTMLKTGSQTSWDGFGVHGVQSPYGLPASGGWSEGFGDDFSDDGSNIHVGPGGAKLYIGSSNNESEGSTPVGLVYMPPATTRYGNSIIPRVNSNTSLSSEAEVELREDANQKDADNVHGDKTVGSVEERTSENGDKVYRHHEAYFSIGSDKDGVLGVRSSSVPIVVRTPAVNVHGNGDDDDDDVAEEDAYDYFGGPDLGEDFAHRKTKSSARRKPQRSSEAVSSPVTIKGNSKTQAVDEERQSRSRSRSRSRTPSPSYVSQSSTPAISVPGRAEHVSSPPPSSSSLLSPPLRGREFVPVEQPSTSRGRASRTSSSFPDRSRSRSNHSSPLGSLSPEGIGSAYSANGRGGGDRERERERSNRNGGRGRERTERHLSHSLSPDAVECVSSLGPDAASSVSSSSSGSQTVVPQYGHADTFESSMDNPSVKVQVRTSQPTPTNSPVISMSGAAHAIARMNGKSPIIIPDPHVSSPRLTYPSHSTSEPPNTNTSSSPPVSPKGSTISGTSIATKDSDHDDTSVVGKAVGIVSSAGSYFSFWNNGAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Q0</accession>
    <name>A0ABQ8V1Q0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="252" mass="28505" checksum="36F912584283A966" modified="2025-10-08" version="1">MSPKRTTRTPARRKAVGLATQNRNTSTRRLHVMMENHSATLTSNSSPSSPLSTVSSDSASHDPLIIPAPSARIPVDIDSIHEFPMLPSGREEYLKRQGGTDELVKGLDTLHTASENIFKTQKEEICSRMHQIRVLKEQCRKYQETICLSKLTQEREHRCPGCENLAWDPQILIIHGRAYVGFIKYFQGTFEITFNLIYIFCSLSLVMKSFMLEGVYAWIQATPYVSFNAFDRGVKLNCPCIPGVLISPSRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V248</accession>
    <name>A0ABQ8V248_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_113003</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000134">
        <property type="protein sequence ID" value="KAJ4464810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF530">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0271350-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="1018"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="1124"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="364"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="665"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="884"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="972"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1200"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="562"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="716"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="743"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="791"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="809"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="824"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="899"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1069"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1219"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1278"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1296"/>
            <end position="1314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4464810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1427" mass="150148" checksum="89F8C9FFA349FBB9" modified="2025-10-08" version="1">MDEQPFGGNPFISKPKRVSLSEPKSSSLLAAPSPPIVSTLHPNILNPPRTPFTPRTPFTPGTAGPGSTPHTPYTPPIYTSVMHTPQAIPAGELCSILFASSVFNPESHGPNSIPLLIDTRPLAIHTTFHIRHSVPIAIPSLILKRSRKPGFGPGGKSSQFTSMHSLRQFVTTDHGRKVFDALLGIDEQQSVRQSSDERLWNGDVVVYDEDMDVKDRTNPSSTPWSLIGVIQSLLDAAASARPSIPTVMSAIQEDLSSVPEEVRIGKADYLEGGIGLAGHDPQLQTLIVGNGDDGEFPAPSSPSITFPQSSEPKQSFTLAKTVPTAAPKQRKGPPPSLGLSGIGGLFQLDTHQASYKTRGEVQIDQSLSSAAPSAAPDSVQSDRTERPLKTTRPLLSSSLSGLSDSDHHILSSVPADAESINPSPLPIMPTFSASSLAHPSVPPSNIHLFPPIHPSLNSHSPEPGSGFFSDSAFKTPFTSLADPTPSPPPSKINFSLGGGSGHSAHVGGFKRPPPPGQVNKRPSAPNLRIGSPVPATPAPPVPQSGPPGSAGKRLPKLSLNTGGVGGLGVGGERGTGFGGGAGGSLGRRAGTKLRSATVGGGPGPGGHWGDRESQTQISNNLPNFGPSPRFTVEPESLAFSPTSNNKNIFQSLTLPLPLSINGNAATTLHPPSPSHLNLTHSNHRVTPSPPGSARLYGSFSGDLKPPPSPGFGRTSFPGSGFSTGLGSRNNIGTKPSLARKDSTQNSQSESSVSLKVLPPGLDHHTEEYEPSSPSSSDRSERSSAASEDESQTSLISLTSCSSSSTNSQKIDESSTSIDRHVRSDSVSSVNSNISSGPKTAYFTPPHTPTQMEPIPPSARPTRAPKSHSTFFGYDEGTGAGGVHGSGHPPNLNLIEHEDEYEHPPTPRTARPEDESGSETGFSKTADGSGPVLPPQLSAIGFYGQDFDEDANFSQRYSYSAYPASHEDASFGGSFGYPPHAPHPYGDRERSSSFSSLYPPPSTESVDSESEGEDPMSFTVSTILPSFLFLGPEPTNWDHVKQLKELGVRRIVNLAAECGPNDWGLGLDKPGNKEKEGSSSLDDSSKESGFEKYYKIPMRDTVEEDGIGRGVRVACEMLDHARLLSAPVYVHCKAGKSRSVTAVIAYLIHANHWPLSKAYSFVLERRKGISPNIGFVSELMGFEEEELGGKSGGVSGAAWGAGKGYAKHHHRQGGAGGAGALPQPSAPAATREDHDGNAAGGSSSNNQHGYGVVASMRKSGNARESMPPPATHAHHGYSYSVNEPSITSRLLSDDNESGSGSSSGSNSASSSTTASPEINGEYRTEALYGNNLGGSGVSQGPSFPPLSAGGILALGDAAQELEVRDANGRYRHARRAPVNEMTLQPMRRVSKAGLESGEFYRGDGRTTWGEEEEEAVVIESDTHIEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2C8</accession>
    <name>A0ABQ8V2C8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_924888</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="15">
        <location>
            <begin position="52"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="266"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="536"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="552"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4470281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="604" mass="68191" checksum="61473F8F840EF9F7" modified="2025-10-08" version="1">MTPNASSTAEPHININPVALSPSTALPPPTTISNILAFLFSLSALRDWVKLIVLGGFFETCRRIVFGMYSKLISSFWMNAYFEDQDPCYNWLMVWLSKQPSWKKSRDVQISTQTYGAKSSSITLDGEDNYSSQFKSYRKLSYLPSLSVTYSLWYKGCYMNIIRTQQETRWYGDKENTLQISLLTRDRDILVHLLQEAREEYMAAQEHHMCIFVNDSIGNCWSHVASRAKRSMTSIILDPGVKELLLKDARDFLESKAWYSERGIPYRRGYLLVSPRQWGAPGSGKSSLIHALAGELGLDVYVLSLGKAGLDDSSLNGLINRLPERCIALMEDVDAVFTHGLSRDSDAVDALVNPHNPSGTPTASTSAPSNNRVTLSGLLNALDGVSAQEGRILFATTNKYSSLDSALRRPGRMDVHIEFKLASKYQARELFLRFFNPGDTPKIVEDNESDSGDSIGSADSGYASTHDTQLTVHSSFRETKLPIEKLKLLADDFAEAIPEYGFSMAALQGYLMMYKTQPLEAVEQIGEWLQKEKEEHATKNQEAQTKKVGSLKGEKETMEQEVTKRVEKAVRERLEREKLEKELMEKVEREMTTRMESWLIERPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2D7</accession>
    <name>A0ABQ8V2D7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_618074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="372" mass="41462" checksum="E4A8092722129662" modified="2025-10-08" version="1">MFRTGSPYSQFFMSGLVPPSSPDATNEVQEGFFYEVDFRRRGSLPDTSSPTASVEQFHKERSFLSLDLAGAGSLRAPSLHTLRSRPSLQNFPSQKPMPKYADALPALPALNTSRASSTLLPPSHSNAIAGPSKSVTIPNLTRNTSTRTASSTVSTNYRRTKRSDALARLEGRSHTALTSFKFGGIKEETTSNFMSLSEDEDSSEDEWDMDSNEDADFVDLDIDFSSTHRHSYSAPSQHDDEEDILPMSPSRSHAYSRSFSYSTSSYSAPSRMQRRRSNTRSKSSYGFGSSIKSEPRVRSKTMSMFPSNATPKKYTSFMDLEHSSHREVSSSLFKQSPRSSSADIIFPLHSPNRKKTEEWLQWSSFIEISAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R9</accession>
    <name>A0ABQ8V2R9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_925567</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045043566" description="CFEM domain-containing protein" evidence="6">
        <location>
            <begin position="27"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="7">
        <location>
            <begin position="57"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4467831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="232" mass="22351" checksum="92C3641900BDE16D" modified="2025-10-08" version="1">MIYSSLLEKSTLLCAFLLYALLPVVAQSSSTSSLSSSVAGSSSTSNSISSGSITASATISGSGSSLSASSTTSAALPSLSGYDTCVVTCFETAIAQANCSSVVPESCYCNSSDYQSALISCMQSNCASELATAEGLTNQFCALASTSTSISFSITSLPSSSSSSSSSSASGNGSTSASVTSSSGTSASSSSSTSASASNAASGIILGGINQAALTNLLVAAFGVLAGALLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V340</accession>
    <name>A0ABQ8V340_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_924563</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="307"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4471679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="506" mass="54630" checksum="EED303F355B49AFA" modified="2025-10-08" version="1">MSLRPSSTTSRNSGVRSVALPPSPSSEFHNNSTNDVPEKGSEITNDKEVPVVTDYKPVELSEDDGIAERMDHYGKAEGDVRAVPAVISPQNDLEPPDGGLQAWLVVFGAMCSTFTTFGYVNAWGVFQEYYQRNILSHSSPSDIAWIGSIQYALVFLPGLPVGRLFDLGYFRSVFIPASALLILATFLIPECKEYWQFLLCQGFATGLACGTFFGPVTAILAMWFKKRRGFALGLFATGSSIGGTVIPIVVRSLIPKVGFAWAVRIVGFILFAGLTAANLTLKRRIPPVPSSEGVFNLRMFKQFRSPAFTVYCVSTFFVYLGFYTLLTYVSATATSIGVSESFSFYLVSIANASGGLGRIGAGLFADKFGAMNVLIPFTALTGVMTCVWPFTRSTSGLIAVTVIYGFSSGPYGSLVSVPVIETGEPGDTNRDLGRRIGLLMTFLASGGLLGPPISGLIFRSRGIEAMGIYAGCMIILGVVIMCIPRFLVLSARRKRGRMTGWILSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V359</accession>
    <name>A0ABQ8V359_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_594581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF3">
        <property type="entry name" value="SERINE-RICH PROTEIN TYE7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="638"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="984"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="857"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="984"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1105"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1306"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1316" mass="136785" checksum="E8A214B691207735" modified="2025-10-08" version="1">MASKGLVRQEGFHPDTSSSGSDLSWRPSSALSGIGSSPHDLGGGGGGDFDQELATLISSERSTASTSSSSGSTTNDYVQRTHNIFDMGVRPPSSSSLHTAHNNSHNQHTPSNSQRSDSPPHPTSIPAHFNSTLPALNSSMRYEPLPDLPTSSMTPVPPTSDSPGLGGWTRHTPSPRPTGTNNNNTNPNNNNGNASAGHPYAVSRSRSRSRPPSAYPGHPGPSASPSILPSPLGSSGIGPQRTTRARRGNSVSSMSSMTSSTSPPPLLQQSAQAIVIPRTGHHHTQSGNGNGGGDGWYGPGSQGSLGSSTGEYALPTPESLHSHSHSSASFHGFANLSLNVSNLNPMGSMNNMNSPSMNISSPLNQYIGSGSLDGMGGSPMGLNGFNPGLSAGGINGMSISGGIGNINNGINSINNGMPNSTSSFNANGHWPSSPGAGDQQHYGSPFGNSSSPHLHTGPHSHQHPGQHPQQHHQGHHEQHGHGHAQMHFGGTHTPTPASFNSSLDRIDRLDRFDKLDRFDRLDRLDGWGFPESRSHSGHSSSNGGTGGGMTPLSSSLPTTSTILPPPPPSSSSSRGHGHSASISGVTSTSSTTTSSSNRRPTKAEKAERAAALDSNTNNNKHLTPAEKQALVANEKRRRRRESHNAVERRRRDNINEKIGELATLIPDVMFGGEGGGGTSNSGASPPPGTDSSNNINLLSPISPTSPTSPTSPSGLPGLTNLSGHSYGFNLDMMGLPVPDEYFHNNPGAAAGGPGSGSGSGVALKTEPMDSDAVVGDEEALIVKGGDGRGSSGGKDGKDKDGGKDGDEAGGVVKANKGMILRKSVEYIRYLQQLVTAQGARNRELERELRTYRGGPVNPNSSSSSSNTPNAMNTLNPMNTIDPGMGGNIGEMEFHNINQMNELHQVDHPGGFDSMNPMESMHGFNGNGSFGGMGSFNHNGNFGGMGNSFGGMGPINMNISDLNNMSGLSGMGSMNSMGSMNSIGSIGMGLSMGSPLSDVDEDEDEHKEVKEEKGFKEQTERRNSRKTKLNTQNLKDSVQPADADPSTIISGVSSLSKEKDTNNGVSSLPSPGASESSSTSSNHAPHSISGTTLPMGKSTRTTRLRANSVKNNISSSASAVNASASHSNPNSSSSSSSTSTSMPKDILSGENNRGRTRRARRGSDVAGGKVGGKAEVLGSVSTSPVARRRRAAVAATHKSKLKPDSEDADVDMDTWSVVDSAVVDDDDYDYDDPEAADDADDGGDDDRDEDYHDGEDQSPNSVASRPGSRSPRNAGGHDDDDSPSAIAMEMDDEPIGRRSGRRNRVALGGGGGEGMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3L7</accession>
    <name>A0ABQ8V3L7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_924333</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the N-terminal section; belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028162">
        <property type="entry name" value="Met8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF6">
        <property type="entry name" value="UROPORPHYRINOGEN-III C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14823">
        <property type="entry name" value="Sirohm_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Siroheme synthase central" evidence="14">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Siroheme biosynthesis protein Met8 C-terminal" evidence="13">
        <location>
            <begin position="318"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="12">
        <location>
            <begin position="414"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00035662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4472670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="764" mass="82817" checksum="7A440FAFD572B880" modified="2025-10-08" version="1">MSPPTPSSSNPTTGGFSVPQPGASLLLSFSFRPSPYSQPAPFFILGSGPLAAQRAFAAIEANASVVILGKGNLENVCEELRWRVNHGQVSWVDLDQFSDITHDTELVNPDLVDTFALDKYFSGLPPSVSPKFLCITDTLLSTTTRRSRASALSIHTLCHSRNINVNTTDYPDLCDFSFATTYRFPDLPVISGGSSSAHLPTNGGALQIAITTNGQGCRLAGRIKREIVTRLPRDVGKAVGNVGKMRALAKERDRDAKQMFPSIFGFSGPSTTEDPEELDPCADTDTAPTPNSPIPQRPGRTVFIQENGFSPDGETTADRTRRRMKWVAQISEYWPLEKLAAMTEKDMKGYLEDEGAETETKAEVDPSVTPIETRSSCMATTKSELPPFSVPLPPQTSIHSIFPSPPNTIKPGQILLIGSGPGHPSLLTIAAHRALTELADIVLADKLVPAAVLALIPSRVEVVIAKKFPGNADRAQQEMMERALREARKGRCVVRLKQGDPAIYGRFGEEVLYFRNPPPRSPSTTTPAVDHPPLPPTLVIPGVSSALAAPTMFDIPCTQRGASTSFLITTPVGKGGKMLDMPKYERSRTVVVLMGVARLRSVVKTLIGSGKDADYPPYVPIAIIERASMPDQRVVESTLEDIEHAMESAEVGAQRPPGMMVIGWSVSALWGDGNVDVLSEGDDGEGETSGKCASEGTGILREASKTIEAEFREKNEQEMKQSEGTKIGNSEDVRRVRNWLGDGVRWRVREGLASTWDLFNIDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4D0</accession>
    <name>A0ABQ8V4D0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_44590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045514060" evidence="1">
        <location>
            <begin position="19"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="126" mass="14233" checksum="80E7A4C0275E4B3E" modified="2025-10-08" version="1">MRLTLPCLVLGFASAAYAAPLTNLAARSAPLSFVNVTFLHEFSGPMFDPPRFRIEPEKAQKLAERTLRGFHRTHSWLHPMRIRFLNELIDVPGSEEVDMSFHGEFEPCHSAPCPATVSWDEHADDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Z7</accession>
    <name>A0ABQ8V4Z7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Phosphatidylinositol transfer protein SFH5</fullName>
            <shortName evidence="15">PITP SFH5</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_774911</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)</text>
            <dbReference type="Rhea" id="RHEA:38691"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:38692"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 15">Endoplasmic reticulum membrane</location>
            <topology evidence="2 15">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Microsome membrane</location>
            <topology evidence="15">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the SFH5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042938">
        <property type="entry name" value="Sfh5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0492">Microsome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="17">
        <location>
            <begin position="134"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4474551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="34223" checksum="8AE0C6D720B9736B" modified="2025-10-08" version="1">MSETEATQAAVAPTDSEHRETSYGVIQESAPEGLAAEPIEPKTALTDQFTPKEWDALKAFRVEIPDALASAYPDKNNAKTAAVKLWGVTIEPSNLLDAKVSVVLMKFLRARNLSVSEGKTMFIATLRWRDQFNVEAACKEAFPQDVFGQLGHIYGQDKAGRPVVYNVYGGNQDLKAVFGDIQRFLRWRVAFMEKSIELLDFETTDQMIQVHDYAGVSMTSRDTNSKNAASEASSIFSSHYPELLHKKYFVNVPSYMTWIFWLFKPLMPSATLAKMSVVGSGASTIGKALLAEVNAKQLPTRYGGEAEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5G7</accession>
    <name>A0ABQ8V5G7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_777939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="94" mass="10626" checksum="24B2F4589FC4C7AF" modified="2025-10-08" version="1" fragment="single">ERMASESNCWVYIAGQHPNARIPFLHFASHRLRLEAPSVLDELHGSADHLFTSLLSSRCQEAAELTDKLLLAQNRIKELESEKVAWERANGSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5M2</accession>
    <name>A0ABQ8V5M2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="446" mass="49851" checksum="8846196F554E09A1" modified="2025-10-08" version="1">MLDKQDVVDADQQELQEFLVSQQNEAAVAAKRKHDCSLMPVAGPSRKKVWSNAPKKRSHRKSPVVEANPELLRRVRLVVPPGQPVVASTSVPVRPRTSPSLMEVPNRDLLMQGPSDLGRLVAIAEVHSGLARQAVSPPSARTPIKGAGNNLLSSTMPPTPRPTLVPRTFTAHPYRAENQCLAARVHLLESQLADSQRENSSLTSALWDTSHALESRQQEFLALDEALPGAPGGSLLEHSRKVQEDLQDATRERNIAVEKLSTSTRKNSHLMTSLLHQQGVVNESNALATRQRRLVEELQEEVHHARGRAAFVDQMIKEYPDEGYYEVILPPLSQLKGDLNKAREDLRRVATFAHRLYHSDPAMVLHHHHRYIGAIIEAVVAFLRRSLDSDDLDVIVHNFPLALDYMQAAPGVHGDLYMRSLSSIQWFFNNTVDEDEGLYRMVLEHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5M3</accession>
    <name>A0ABQ8V5M3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T-complex protein 11-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_853640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="580"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="753" mass="84392" checksum="84C6216221F3BAE1" modified="2025-10-08" version="1">MDPPHGLPRKRKQVPDDVQDIEPAVVDDCQQVLNIPRYSFKKPRLHRPDRFTRHMRKSHSSSRPPPVDRLGNDIEDHGIVSKAAPGPLTGSLLHLRKRPSPIITIEVSTALDLPVPVNVAMARVPSTYPYVSRNTLKELDLDVILRSPQLRHDLMFDNGLQFRPTYSRRKRQLIEAYWTAVIREVESGCTCFSVDKIGAPMMTPACVCNQIPIPPLHPIIGYCPALQVMTVRSPSRIRPLLSEFLEVLLLVIQPLQSVSGMYVNPDSFKAQMEEHSTQADYFRSIIDPALIEQELRHNLFDLSSLLRAIGVLLKGHCAPMRDSAVEDMVRAAETCKPGGPGTKAEGVNALRTCLEILELMKLDIANHQLQSLRLSISRTSAVYELQNFQAKFVTCHITRQWLKSSAATLLSRSSHICHPLYLPEKIDFHNSGHNRQIYLCALKGVIDLVFYAPGATIGEKFQNPSTLIPDYPETLHLDRMRLRSLSKDLDDIVISYMLLLLFRQLVYSSAWNDMTSRSKPDDATLLKIKHEITIINSARPGHAMLYGFRQTDAEGTRSADFKENVVLHIAKRAQQFRETTLDDLPSASSSTLNSPATTPPTSPISENESPVSPSSPFPHALYSLSSYNLDSPPDTRILNVARRWVVENINIASPLCSVIYDRLHEVVFTGVVAQAYPGRQCTTGQLFSSAIESSAPLRQGGQPHTMPLFSGMEPLVDEIRNLTDKISRVVIMHLNVYLPIYELNGFLEDPVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V671</accession>
    <name>A0ABQ8V671_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_869747</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1330"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="72"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4476287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1353" mass="153292" checksum="E972D532C82EDDD6" modified="2025-10-08" version="1">MLPVIFLFQQPTSRTTAATTSSDDVQFIAGPFKATYPRKSLPQKLAVIKHKNKEARERTDVFLLKQRENLNCHICLSIVNRPFILSCGHFFCAECISECAKYHVQKRTNPRCPDCRVITGHFTPIEAHHLQQMAVALRSELGIPQPPRGSLKWPSIFKDLLGSLKDEPLKLSSLSSPPDLSSKSTSSPDNAKPKLHWPSAAAASDLRSKYQTLSRHADEASNYNMSVMAAAISSGMQSATPQLPSIERSLHKFQAEITKQTVKSMLSASAGTPSVEENSLESLLVPDRHGRLQFGDPRKSSAKSILCAVEDGSDTLRREIASSTAAVSVEAKEVRGVLDSIQQSVQLWRTKYPNTAPVKIDNRKCFFDPTQDKNSPTVIAYCIALVARVFERTAQRGATFILKMIKIFGYTLATLGGRTLNTDQEIALAGIPESIERLEKKFNLDVDCVPYAVCPKCSMTYAPSFPNGASHPVYPPICLERQTSSEEPCNASLLSYGKPAKIFEYYPFFDWFGKFISLPRIEEYSDKFCEAVESHQNVPIKKVDQTDSCFVHEFLRADAQLFIADRNRIRGKKSSTGMMAMSCLNLPLKMRNDHAYLYVPGIIQGPHEPNAINAEHRYTRGIRPYATHRTYGKDCPYDRIFRVALALVLMDFKAARPFSGFLDVTSHHFCYMCDCWHVSHLGRTDYEEWKSADDAFLRKGAELWCDAPDTKKRKILEDMFGTRASEFWRLPYWKASIQLGIDPMHTMFLILLQRYFRDILGLDNPDDPKRTPKKPKFKFAFYHNFTPPPPLSSLISNDSRARQAVLDILNDLSERAPVTEAQKHQLYSRIQRHKWSAILYVCDNLAIFPNERPPDLRNSSQITQKDVTKRELSNILLHWRTHEIREEQLFIWPYFTPTDIPPPVIPWATHHASTPDHDNPIMYRKFTPGERSNLLRELAASMTYHSASHVGNLHRLLQKPLVHDHKDDLRKALKQSNGDALTYVCADIDRLPAKDVEAARANAINQVRLFQSLAENSTVMAKRTLSVERRNLYRHLLRLHILGLKQDFPGWIFPTHHLAFHIFDGMNNFSGVRNWWLFPFENLIGKLQRIPTNHITGLFILLSAWGLTYIGKIGQFEHTMLHSFCKGASFRQWLLRENSPPILRYCQQLLDKAYNYDRGSSAPPPPVAPADDIDDSEGSITVDAELVTSNFAQPDSKYKILPSPTLTRLLRAEPFECFSRIPGSKGDYTIPGEGAIGNSNICFQAQGTYRPGQRWIAGQIRHIFRRTQNGPLQAVICWSMPASTPHPFADYWANGFEADMVASNFSDTLEIITLSQIAGHIARWSITNDLVVVVNLCSVSLIFVYLLFTLNML</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6T8</accession>
    <name>A0ABQ8V6T8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045402113" evidence="1">
        <location>
            <begin position="28"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="260" mass="29627" checksum="D0B3D8A7E0DBDC71" modified="2025-10-08" version="1">MLLRQSPFFPGLFPICLFLSIVLLSVAQPTTKKPTRAGGRLPGGMIIRLGYRNIGDEQYGTTSQLHNRFDRSTKFTIFFGTIVGLTTSVLDNQLVVQTREIPRAEVRNARGNFGVRKYQLIKLGKDSNSQLVTNLDEHQATRDFLVQELSDPKKLLKQTKDLFYKKYDVPAVDFWQDVADNGEYISIVLIYLTLLEGRDHEPALAKGTLGEWIKTYRAVKTLELGDDYVTKDPHFLAIFYLLNGKYEAPETPFNWTAMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V775</accession>
    <name>A0ABQ8V775_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_925246</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF2">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="55"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="516" mass="57069" checksum="1D885D58A0671EF9" modified="2025-10-08" version="1">MAITEEKPESTLREDVVNANLEKVLARHGRVDLAPLPSDLPEDPLNWSSFRKNMLLALVAFHACLGPFSAACVIPSFEDFVVDFGITLTEASYLVSVPIVFLGTIPLLWAPVSKRIGRRPVYLVSMLLSSALQLASAYCTTYGTLMACRVLVSVFICPPQSIGASTVSEVFFVHQKGQKMGIWALLVSVGSTIAPLIMGPLVYHTGQWQWTFYFLAIINFAHFVLYIFFCPETLFDRPERSKIGSPQITMDEEINPGKWYTPYTSFRIHSTEPWIGLPLDVISPLQFLLKPTILLPGLAYAITFTYTNATLLGQKYLLNTQQVGLQFVAPFLGALLGEPIAGYGSDRWMQYRVRKAGGEREPEWRLPFAIPGFLIAIVGLMIFGVQLQNTRAGVWNVTPDVGSGIALFGLQLVTTVCTTYAIESQPEHTGQAALMVAFIRQMYAFTGPFYFTLQFDSMGTVNACGLLSGLIAIGMCFVIICMIFGRSWRKGEEVTNDSEDRESVVAGILSDEKVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7G0</accession>
    <name>A0ABQ8V7G0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_845952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="41321" checksum="2B8B7EF9F1E09EBB" modified="2025-10-08" version="1">MTTALPISLPGMSAAPQYLYGSRFFPSASGFEIKGPVFNSHIYPLPIEAPPHASTFPSPSKLTSLAHDYNSVPLVESEIYAQMLLLRKKGYPLWKPKSDNSRLPESYKREGIHIGDVGILTESGGFDYLFNICQGPDHELNLGRVPEDFRPILDFDCDDTEDYTQEYELGSHVASDPNRIHQRRIPASPTPNNPFKNRLHSAIPDEVGAGLSYSSTASKGALLVLPEGGKRVDHLHRARFEKYAAECAPSWYMHVNGALGRTAYNGSLYLVTGFDKARAWGVASFSDAIPENIQLEYVPKSTHSEDRYPKYWFRTCDSASSSSGADDRYGQQSGCIFLRGFKIAVRETCAKSRSSLVVDIATVAVSSSSDTYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7K4</accession>
    <name>A0ABQ8V7K4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_844372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045043649" evidence="2">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4478581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="19466" checksum="E17A41437FC890A5" modified="2025-10-08" version="1">MRVFIFTFFTLFLVFARAQLETVLDADGDTVVEDITTNRQGLPTTSIISTILPGAATTATTATTATTTAKTATTTATTLQQGGGVVGAPGTTNTVDPNGPTPYTYTTVIAGVTTAIEATFIPTFTTALGTPAPATGTILNYSQWLSEFGSTSTAATSSASRVSFNLSGLLGMVMFTVVTAMGLGSFVVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7L3</accession>
    <name>A0ABQ8V7L3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_773427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052925">
        <property type="entry name" value="Phage_Integrase-like_Recomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605:SF4">
        <property type="entry name" value="DNA ADENINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="17374" checksum="06DC094518705E74" modified="2025-10-08" version="1">MPIQYAHLCPVRAFAKWLHFSRVKKGYLFRKIRQNDQIAEENEPMTSEQFLEMFRNNLIDIGTNYFPYGTHSFRRGGCQWLSVEHRWPLCQICEWGGWSQEFTHLTIVKYLISWNDNPTINCYDFFNMHRAPATVCPTCNRSCHCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7P6</accession>
    <name>A0ABQ8V7P6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_869315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="37455" checksum="C52F17D0A0CF4EE4" modified="2025-10-08" version="1">MQRKDMDAFKGRKAGLNEFWKEEPLPNRGDEKLLRLSMSAEVLLRMTRVLWKMSYQALTMVIRSRRVQPSSTLDRCSRFQGGVIVKQNDARRISTMPVYVHYSNLIRENCHPLSWTPSLMKLHRRASNQKSIWMKGRTVFVFPSAVQLRRGLVELIATMPNREQQNYEDTKSFLEYYSDQGIKLAKLGYTCLILNEALGLCVPSQPWCIDTSGEGLQYQCMATLSLDAAIKAHFSLLAMKSRNSLNSETPKTFLSKYDSNLIMSRTLQNVVSFLQYLIPNRNALNAAHENQAKKFIDDLRTMIVIQLHDFPIDQHALEMFRPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V840</accession>
    <name>A0ABQ8V840_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine proteinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_852163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36876" checksum="91773D6EA27E9CB8" modified="2025-10-08" version="1">MVASPYYLPEYTTTTAPGPARNHYDHHYHQRAAASFYQSTKATNQSTYPYSVPSSSHSVKRTPPKPVIAKPLFKPTLPKDQTDLRVCLFHQLRDASLRSHVPGGFPFRHTLSDLKGKTKVRVSYEPYDIRLSNENIGPNESIGIVYKGPVSAKHAGNNNDAFAAGGSSGPRSSPQYFTWEAYASVREARWNGQGYMYSKSAHKTILAQVRVDPAVMHTSYGKFLRTDSRAISRALAISLELGVLITIVSADENLNSCIDSSLLARSMMRHRRDGDVQVAPEYLRYWSKWISTDEYEYGYGENGPEKPILYIGTTNNGHVDLLYSYPNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8B9</accession>
    <name>A0ABQ8V8B9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase family 92-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_498502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF43">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045599339" evidence="1">
        <location>
            <begin position="21"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="31"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="329"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4479866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="914" mass="99944" checksum="4DD621B592A11A86" modified="2025-10-08" version="1">MYPIFSAILLSLSSLSGTLAYQWPKSFLSSINPLIGSAGPEPNLSGGMIPSVAPPFGSTRWVAQNQESYVSATPFNYTESYMNNGTIHGFMGTRQPAIWMGESAWAAVVPGIASGSDGDILTGFEERAMPKIAGTEKFGVGLYSVQLVIPESGGSTVEVLMSASSRVGHLQFTFRQGSESQFQPYIFLPTTRPSTIFHNPNTFETTYPNGTVQISPSTSEICGSNTEMQDFILAPNSIKDAASHFTGWYCATFDTSFNDIGYGITVGSGDSTMRTERAESGSGEELGAYARFQFPSSNGTENNSITINVRIATSLISADQARYNLNADSENEIGSFNIQDTQSDTENAWAEKVGRFHVETDGSSESEEKLAVFMTGVFHAMQYPYEVHESIPTTPNSQQYYSAYDNTIHEGESYSGYSIWDTYRAEWALLILLAPERIPGMIRSMLQDFEEGGWLPMWKNMIETNIMVGTHADSLLAEAVLKGFGAGSAEENGIQTTFTTDELTTMWKAAWKDASVPPVGDSNVVYSDREEDVDYEVRAGLSTFFEQYSAGHGWVANDIHSESVSRTLDYAYDDHAVALLSTLIPEDIVQGNTPNLDEIAAGFYNSSSVNTNYNVTSLLNDRSLANPWTVWNDTASAPAPATGGEDIKGFVQARQQNGDWAATTDGFTEGDRWVYSFAFVHDVAELVERRGGNESFVKSLNEFYDGGWVDFTNEPAHHTPYLYALAGAASYTQERVREIAKSNYNNTPNGLSGNEDCGQMSAWYVFSAMGFYPVNPVSGVYVVGSPFFSSLNVSIPVPPFIPPSHPSITSNSFYNSTTNSYDLRILAPGAESKPYVKSLKVNGRVIGDKEEPLISHEEIRSGGLIEFEMSDKAERWGGGRGAWTEITLDARMSSGVVFNDQSRSSIVSVEHVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8C5</accession>
    <name>A0ABQ8V8C5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_851618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4470729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="220" mass="25355" checksum="0F830CF166AE641D" modified="2025-10-08" version="1">MNSLSASEQEPLNDGRIISYFLVSSIVLFLYDWILMLPAEIKFVWNTKLRPLNVLYILQRYMPFIDTIAFASTASLVRPMNPDTCRVLVNISGWMSLAGIALTEVVLTVRTWALWENDIRLSFGLPIFFVCCWAPSFYVLHVFLQTQTFIPSPFPQEFGCTYLGGQSVFYLCWVLLTVYEAGMLLLMLIPAIKSFRSGRWFTLTRTVYRDGITYYIVLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8U5</accession>
    <name>A0ABQ8V8U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase family M1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_549300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="10">
        <location>
            <begin position="480"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4475116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="638" mass="71572" checksum="761905C1AAC0B070" modified="2025-10-08" version="1">MADDPTSQANYTEIATEHVSFKWTIDFANQKIAGSATHDLRVLKDDIGEVIFDTADLVLDSVEVEGKSSSYEVKPKHPIMGSALHIPLPSGLKSGSLIKATIKYETTKECTALQWLAKEQTQGKSFPYLFSQCQPIYARAMAPVQDSPSVKIKYSAEVTSILPALMSAIRQSPPSDGPAHDGKVIGKDAVTYIYHQPIPIPSYLIAIAAGNVVYRPFPRLPGKEWTCGIWSEPELIEAAYWEFSEDTARFLASAEDIVVPYRFGVYDLLVLPPSFPYGGMENACLTFLTPTLLAGDRTLVDVIAHELTHSWFGNGVTHAHASHFWLNEGWTTYIERLLLQVLHSPAERGFSFIIGNKALKDDLEMYVDRPKYQRLVIEFEKGEDPDDAYSRIPYDKGANLILHLERTLGGLDVFLPYVRDYVSTFMGKSITTQQWKSHLYGYYERNGGAEKIKALDSIDWEAWFYGEGLELPVKMEYDSSLAESAYKLAERWDSSRSVEISKLAFQANDLDAFSSTQKVVFLERLQSYKPLPSSHIEHLASLYKVSSTHNAEIRLRFYQFSLADPSSPAAQKYAAEAADWVIGGGSGMVVGRMKFCRDVFRAVFKVNKDLAINAFQKEKNSFHPIARKLIEKDLKLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V995</accession>
    <name>A0ABQ8V995_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_552656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35154" checksum="BF28B66B7BD4A036" modified="2025-10-08" version="1">MSIQQKHVLARSLVFKQLPPSLEVKQALSCLPRGRFHDIVPRGKDSLAIKFLDFRSASRFTQKFRLLPRAPLLKDATIEYEASGPLPIEILTAIGLRNASRVVRVSATIAKDIPESLIDDSKKCGPIESFESDKRKAVINFLSIDAAIKALDILRASKTYVGYHVYFGYDKKCDIPPPYPARFKTDLVLTDLPKGATTNELLQRLQSGLPDLKQETIRSIVFDEPGAKAFINFLEPGVAKIVYGSFKHAKTSTGGVSVSWSRTTSSPITASLRMAVNVGASRTMTISHLENVEQMRRVLKVAKKLGTVVSHSYNPSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9F1</accession>
    <name>A0ABQ8V9F1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_473633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="31991" checksum="99ABD12422BC6FD0" modified="2025-10-08" version="1">MQNTASLFSSNSSISGTSRAESPPAVDVPIDNPSIPVEILKRPAAARKKKLEDDPWTADVSTVSVTCLGCGHLVRLSTKSLYDNHHWLMHKQRCKRAGNMKGSSDIGASPQPSVPAQAKYKPNTKSNRKTKRAPSASSSVSSLTPISTPPLTSDEEDDVDVSSAEESEPPPRPIPIRAPGKRDLLTEQYFARAHGIRIRLPPIPPDTPDTQNDWRNWKWSELRMPEFTTSAPSLPDSNSDSSEVTCDPDVAVKSQVRAQVEGPRILRSSWSIVQPREREDPSRRPSSSYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA37</accession>
    <name>A0ABQ8VA37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zn-dependent exopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_496567</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="196"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="363"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="701"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="627"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4479827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="791" mass="88470" checksum="14B971535AC3E0AF" modified="2025-10-08" version="1">MRTEKRQENYEKDQRHLRDRFLCLTVGLIIIGFCLSGLLTTSSDFANRRTEIEPFFLSIPSRDTARDFSKEFSKMPHTPGSPRDATLAKRVLQLFQEELGISPTAASIFPAGSPESRNATLRLTAKDRVSQPTAWIDVYYPDLDTPKQQDVEVLDQYGQTTWAANLNEEGDPLDEDAYHSRNDVPTWHYYSADGMVEGKLVYVNYGTKQDFEALLSAGVNLTGKIALARYGEVYRGIKVENAQSSGAIGLLMYTDIRDDGRVTAQNGYAIYPHGPARNPSSVQRGSAHMLYIYPGDISTPGYPAYQNASRQEPSNVLSIPSIPISWKTAQALMEESGMFNDSISRKLVRLINRVDRAPAPIWNTMAAIPGHIKDEVVVLGCHRDAWVLGAADPVSGTVSLLEVVRAFGALLRTGWKPLRTILFTSWDAEEAGLVGSTEYGEDFGEWLSRYAVAYLNVDISAAGPRWLIYGTPSLSDLIQRTAQDIPHPTVKGKTLWDARHDRGFEYDSVEALDSRPNATDIQMLGLGSDHAVFLLRLGIAASDQMFKGVTEFDIPYHYHSIYDSHRWMQIYGDPGFHRHIAVARHLGLMTLRLADSLILPLNASRGASALDNYLTSVETKFNASRNLHVLRQSIARLQAASAELEEEKNESRLNFFDTIVGKSPSFSSRIFGATSSGLYRPYNPYSGWLGQFVSQTSLKWFEEEIRQAYIRVANANKKSMIFDRGFLSDEGLPERPWFKNLIVGPDREQGYEGTPFPALAEALQSGNSNRVEYETQRLMNLLEGLTVKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAH3</accession>
    <name>A0ABQ8VAH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flavin-binding monooxygenase-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_772764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4477917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="499" mass="56357" checksum="407028F0BBF3A81C" modified="2025-10-08" version="1">MTLNPILFAYQFIQHILLRFFAPEPPPPNAKLNRPRIAIIGAGLTGVSSAAHCVGHGFDVAIFEAGDRGHLGGIWARVNNTSGLQIHSLMYRFFPNLEWKSGYPNRREILDNISNIWHQYSLEEKTKFGVTVEKVWQDGHGRWILNDEQYGKFDGIIAAIGTCGEPKMPHIPGQEKFQGNIYHSSELDGKDAKGKKVAIIGGGASAVEALEFTSAAQAAKTFVLSRSDKWIIPRNAIVDTLLAMNIFGQEILLSWIPEMLLRKFFYRDLADLAPPSNKGIFTETPMVNSDVLDKIRDGSAAWLRGDIVGFVKNGIQFTQRAQGVPPGGPGKEITVECDVVIMATGFGRPKLSFLPDDCFEEPYAPPNWYLQTFPPGYMSICANNCTYVNAIGTVGNYHIGIYTRILLMFLVDPLTRPRQGLMKAWIDMTRLFKKRSPTPAFDFFTYTELLWWYFFCVAINPFRWKWALFVFFGIGKGLPMKFVKEEDMLRERLQQYNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB80</accession>
    <name>A0ABQ8VB80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_707279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4485121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="283" mass="32235" checksum="627AC201F2D3881C" modified="2025-10-08" version="1" fragment="single">RGSRRARSEADKHEDAEAGGSRKRIKADVGKYKWNDANSFLESIFTLTPAHQTVREQVRNYAADIKESLRDLETAFGKPFLPNSQWKNILLNRYCDLDEIAANIYTTEHVEPEIFTVGESQLALRRPQPTKKVGDESTWNHAFRVYRDAVNFAFKGRAKELEAYERHIVSLFKARHYEFRSQVIIYDRAVRIHVGGRHDILLNEFHKFADFKDATLNAGGVLFGAGSASGSSQPATHSDKGKHRSINEICRNWNFKQCARSPCRFRHVCIDCGKPGHTATKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCB2</accession>
    <name>A0ABQ8VCB2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="1">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_416205</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="120"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="279"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4486987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="36491" checksum="248A4E0547DF799B" modified="2025-10-08" version="1">MSESSVATAPIADNTIAPLTAEETVSEVTAEGASVEPPATVAVVEDELEAKDEQSVEKESKETKAPSRRSTRISSKSQPEAKETPKPKRAPSTKKRAVEDGSEGAKATKKVKADPAEAGPALGSFLPEITLKSNKEVDVEVALLAKEKGVVLFLVPKADTPGCTNQACGFRDIYAEFTSAEYDVYCVSADPPAAQSKWQEKKSLPYSLLSDPERKLISALGANDKGKTKRSHFVFSKAEEDAEGKGKLVDKHIGVKPVDSPKIALEFIQSYVPVSSGTPIETSNGEANSAEHAGVTTSNGTVSSTKETVSMEESIEKPDVEAAAPATNGSEDKDVVMEAAAPIVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD07</accession>
    <name>A0ABQ8VD07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_767447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="35"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="32640" checksum="5A2321D4DA026C2A" modified="2025-10-08" version="1">MPFIHVKTSSGNIKFHYIISTPDSDVADKIDPDIPVLLFFHSLAFPHVFHSQFGDPLLRKFNLVVFDMRSHGETEGDDLPDGYGVEEAAEDALAFMDALRLPPCHFVAMDYGSPVALQIAISYPDRVLSLFFISQTCLEEPPEVREGHQQVYDCWIAAFPGPDKFDNERMMEGGYGFAQFMFSNNMTKMADALFKISFELSQKHWGYQGLKNYRIATLDFLYNRKSQPRSALSRIRCPVKLVYGTDDVAYPQEYNEKFYRELEDAGVDVSLLVVPGAPHFVSVAHASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDW4</accession>
    <name>A0ABQ8VDW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_958545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="953" mass="107656" checksum="7258AB9BB84DF3DC" modified="2025-10-08" version="1">MQYTPDEVRYSKYNQIQVFNDPQPMLMKGQVHISIVRIFWKSSRSEDWQWRKHFATISIDGRSRKSLDHTLASEWNEKVTLHISGPGTLNIGIYAKHAILQNMKIGSFEEDLETLVSQSLNKKVLSRPLRGCSGSESGLVINFNVECEIGQDCTALSALVQRAKIQASRLSQLQMVSNRMDVIACTNGNIDDMGSLKSTWGPLLEKLQIFKNLAGTIAKVHPYAQVAYDVIFVASEIVLKQMERDNNIISLAEAMDDAWAFVKEAEPLSQMNSRTNIINHLAQQTTDCGYFISAYCGNKSWVRRALKHCYIPTDQAIVQYGQKFIELKAALLGHSAISTEMMVSRILRNMVQLKERMVLENFPYAAGACFQTEKCCHFSTRQEIMSKIIGWIDNPESNPGNIFLLTGAAGTEKSGVAHAISKHYHRLDHLGSSIFTCVSDETVVKTTIPFHLIFPTIARDIADLDPKFRHALYAAASSMAVRTSRSPMDQFTNFILTPSQYLAILGPIVVVLDGIDQMPESSTRGNFLSVLTQRAQDLPSNFRILVTSRPDSPIMHHFSSVKALTVKIEDFDQQYTNYRLLQFARSQLHARGLNIKQEQQLHLRLVQKSQGSFQCMAKACSELCGMNVELDSQALSLHLPGREQHMPLVPPEDSLYQQEIDYLQRTGGKTITEGIDFLKGNLRNSSISMTLKEIIDFRKLANEQFQGNSHENTLGIINTLFLNPSDDYFERFLCDKARSGELDMTGSNYHVAFAKACLRLLKMGSKSYIMPPQLPSSIPPELCYASKFWLRHAIAGLPTKPKELDAVIIELLESCDISWVYILNTLQCTNIAVEGIKQLTSYYACASENIKDSFMDKLEHYKMRMNQFLTFFGDNAFQSSENIISTNFKSAPPTQWTCTTHYTYSNQILASYTEQNDCPYLISLPLEGSSKKHLQRLCIEVKCHDQGKRFTCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDX4</accession>
    <name>A0ABQ8VDX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_957625</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="396"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4485111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56491" checksum="DEAE34D60DE30A8B" modified="2025-10-08" version="1">MAKPPPASPAPPAPLSIPPNPPNHSRSNPPQTHTHPPLTGNGASKGKKKNDAPVDPATMYESLKNRIAALEEEEELEEEEERRFAEEAHKSVKGLEQNTIHAKYIELFAEFKRLERDHAKEKQKLSKDKDAAKSQLTKANQTKTKMENLARELQKDNKRLREDGKRLAQCVEDAQDELHQMKADIAKRTSKARLLDNKYREKPDILVKVSCRYRAELFFKISRKTKLSKLFGAWTERMERTGHGVTSVSKKVDGVAPASGTNVDPGSEDVVPPSFSVPAMQFVFTHNGRSVDADMTPEEAGMEDGDEILAVELMDLTESTGGDDLYDQILEPQRQKLKKNWTDDPHAAQRSLEEIFDGVVRERLKEVLRQYELRERHFECVIRSKELEVLLSRARAAEQKQLASGDKARADKLEEEIQQLRKDLEDSQNGQTMLIDKLIQCCKEIRNEKPNAERTQRLFASLRDELEKRAPSLNSNANNSNSSIGGVTVNGKKGPADGHVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE06</accession>
    <name>A0ABQ8VE06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HSP20-like chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_867723</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4489846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="105" mass="11792" checksum="7CA85D5545542FE6" modified="2025-10-08" version="1">MDLHENALKNTVTANFELPGLRKEDVNVDVHDGRLTISGETKSSSEHQEEGYAVRERQSGKFSRMLWVPRGVKEEDIKASMNDGVLTVTFPKTIPEPQPKKITIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEW7</accession>
    <name>A0ABQ8VEW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_833316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38426" checksum="EDEB627A721D943B" modified="2025-10-08" version="1">MADHPKPKSRSTEDIENQMLVDKAECKISVNVVDFYHNNHMVVIQTQEIDKTGKAIYSRFKLHLSSLELHAPVLANFLTQALDNVEGTEENPVILPFTTPEFTCFLDWIHDREWRPFKITEESLVDLLRVSSTLKAEVGISYAVSGLESLRLPSARMLQLVGDFHHLPEVHYWVGPAVKDLIQRPLGEITNSEAQQIAAAYPTIARTRENIQRLLTQVSQRSFALKLADKDQQEEADLCLTHKECQKAWKSVWKENIGYLLLDFQKPLTYRELLELLRNTDFPKVNPSCKARMLNWLSRKTDYPGMKELVEEAVASIEDIYHVPRRGPAPENPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEZ6</accession>
    <name>A0ABQ8VEZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_895878</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047325392" evidence="3">
        <location>
            <begin position="26"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="72"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4491670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="389" mass="43616" checksum="A60DE54CCA7F4C13" modified="2025-10-08" version="1">MLVTTSLSYALSLVLVSKYFQTTSANSSDSPFNPRDYAKRTTSCKAVKRDANNQLVDIALSYVDINPSANTTLVMLHGWPSLWSTWSNQIQEFKHDYHLIIPDLRGFGPSTHPNDVKGSGTLYDLVGDLQCIIEDAKVESVVCVGHDWGTAICYEAARSRPDIITGVIGAVVPYIPSAGAYVPIKHLTSAIPKLTYQLFFDGKTAEAVEELNKDMRRTVRATLRTKDSPPPDDYLTSPHSFLDAWGHVEEIPPVPFFTPEEEDYFVEQYQLQGFKNTLQFYTDENRHASWKFAHEQGNHTIPQPVLAILPTDDPVADWVIASRLLHSEDFLPNLTTELLSGAHWVHLENPQQFNMAMRTWLNKYFPSQGSEAEALAVDDTYAGHVEGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF03</accession>
    <name>A0ABQ8VF03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xaa--Pro dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_768452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="84"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="458" mass="48510" checksum="E1B61C0C7DB23EE7" modified="2025-10-08" version="1">MFSLRLPKLAIKPWIPGPPRSITLINVLVVDPASGSLLGTNENELKHTIIMKNGKFAEVRPTNEGDKNLVEEEEVVVVDLNGAYICPGLIDCHVHVTAVAGVKSMSELMRVSAQEVHLRTTYNLKGESLFRGFTTVRDTGGATKVLANAIEEGLILGPRLFQCGKALSQTGGHGDFAPALSGGHELGCCGGGDVGLFARVADGVPAVLSAVRGELKSGADFIKIMVGGGVASETDAIETVQYTAEEIRAITTTCKQMGGKLSTAHAYTVESIRHAIENGVQGIEHGNLIDKSTAELMSANGIYPTPTLCCYSIMTRPPFEDFLPPAGKVKNAEVMKQGLKALKTASDAGVTICYGSDLLTSMQALQTEEFTVRATVLPSPDILRHATTNAAKMLDRTSLLGTISPGACADLLILNANPLEDVTVLDRPENHLMAVIKGGRVVVTSGAKELETLEGLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGF2</accession>
    <name>A0ABQ8VGF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nonribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_764369</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="466"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="971" mass="107045" checksum="05D022F9062E8262" modified="2025-10-08" version="1">MRQPFPISPRNSPLGIVDLLRKSSAHRLLATHATLSGLIDDIKSEIQSGGPYVLNIEETPNLQEVFPCLAKETLEHPFNPPVRTFTPKDNGTALYLHSSGSTGFPKPVRLSHLNFKNYISMRSLGFKRYGAAGLPPFHVMAVFNQLFVALYAQITVCLLPPVVTKPDALPVMMSADNILENARLTQASAILTIPTFLTIWSHSEEAVQQLTQYTLVFYGGGPLPPSTGDYLVSRGVKVVTAYGGTEMGLLVKATIDPENWSYAEFSDKCKIRWIPQGDGTFEAQFLTTDLHHPAVENIPDVKGYATSDLFVPHPTNPNKWKIVGRVDDVIIHSSGEKTVPGPMESILTATPLIQGAVMFGRERDQTGLLVEPSMHHEIDVTDPAQISAFRNSIWHVHHANRIAPAFSRIFKELILVASPDKPLPRVGKGTVARKAALALYEPEINELYAIVESNSGGDSVDPPKSWTAVDVESWLIAQIMDILSSGINVNPKLDLFEQGFDSLVSTILRLHIVSALRKTNAVFAREVPQGVVYSHPTVERLARYILSLVNNIDPDASPAKTRPQLIEEMIEKYSQGLDAPFPPPKIPLNTEKHHVLLTGSTGNLGAELLAGLLSNESVHRVYALNRPSSKASMLDRHSTRFEDKGLDTSSLLSPKLVFLEGDSSNDNLGLPENLLDELRKNLTLVIHNAWRLDFNLSLSSFESHVKGARSLINLARSSQHSSDIKILFTSSIASTQSWDVGNGLYPEEVVMDSSYAVGGGYGESKYVTERILVQSGLQVTSFRIGQICGGEPNGAWAMTDWLPILIKSGLTLNKLPDAHGVVSWVPMDAVTSTVLDTAFLNDRAPIAVNVVHPRPISWSVVMRNIRHALVREKSLSPEDLTLIPFQQWVLELEKHVNSSSDDLPALKLLNFFQLQASADDRIKETQAGESLGLTPLKIENAERISQRMKNLETLEASIAEKWVKYWIRSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGI8</accession>
    <name>A0ABQ8VGI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_833473</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="5"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="108"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="204"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4491875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="32073" checksum="A92F1DEB497017A4" modified="2025-10-08" version="1">MSKTIKDLTAGTAGGIAQVLVGQPFDIVKVRMQTAPNGMYSGMMHCAGGILKNEGPLAFYKGTLTPLLGIGVCVSIQFGVIEYMKRLFTHRNIASGIGGSTGKDLNAGQLVASGVAAGLANGFVSGPVEHIRIRLQTQPSINPPYNGPFDAMRKIYTAHGIGGIFKGQGVTFLREATGYGVYFLAYEKLVQREMRLKGIRREELSPMNAVLYGAAAGYALWAVIYPIDMIKSRMQTDGFTPTTGRKYASSLDCAKQVWRSEGPKAFLRGLGPTLIRSPFANGATFLGFEMANRFLNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGR5</accession>
    <name>A0ABQ8VGR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_830476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25251" checksum="142FB57BC3A87B23" modified="2025-10-08" version="1">MNATEDLSSASPPTKLRPLSPKQERRLVVFLDNEFLELTRGYKKRSSPTSHLPTLDAYLQAAQRILGLILQVPPIDPSTSLRIQLLLRLTNEVLTCIPGYPSNSENLPIAMDWLDDLDQSWAAVLQAQVWNPSEGIGEDLIVDAGDVVRGVKSTPMSPTERTRLKSLLLGGVATLEEWLEGKPIGVNRQAVEEEDGLNDIFSNTLEELGHLGLVAVEPEELCSMDLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH41</accession>
    <name>A0ABQ8VH41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase subunit TIM44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_883208</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Tim44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017303">
        <property type="entry name" value="Tim44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037871">
        <property type="entry name" value="TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim44-like" evidence="13">
        <location>
            <begin position="302"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4491711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="462" mass="51825" checksum="E218FF853D3DEBAC" modified="2025-10-08" version="1">MLPRHLQSLVVRNALSRTIYSRPNQSFFLQPRNFQPSSSIQTRQSRRGFHSSPLRQNELPKSPFQTFVDVLKDELKKNRELQDNVKQLQGDVDKFQDSGAMKKAKAAYERARLTSSIKENPRLRVAAEELRKTGVKVSDAVSEALKTMEESEIMRAISKASAAVSSTIEKSTEPIRKTAAYKSLAETVIDALDDSGSAKHAGFEEKEARRLRRQRRLEKAGRSGNGLGVGGRVAANAEAGSALVLHASSPKQEKWETLKQTNPLLRTLSSWKTAYDDSENPVVSSMRSVTDTVAGWFEENETAQVARMMKALDPGFTQDGFERELREYIVPEVVDAYLSADQEALRAWCGEGTYNVLWATMEQYLRQGLVSDSKVLDIRQVDISAGKILDNDLPVFVIQFNTQEVLLFRNAKTKEVMVGAEDRVEQCIYVAVVTRVEEELGNELTGGWKVIEMARRSARAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHU9</accession>
    <name>A0ABQ8VHU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_308693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="79" mass="9360" checksum="EBA2ED8B5AC0B164" modified="2025-10-08" version="1">MPLLQIQSMIFALPRLTENIAVFGQFRGRLAWFIRESVKTFGKLVSEGGACLMDFYFVVLYHRRLMKLFPFPLRFISWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI16</accession>
    <name>A0ABQ8VI16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_828541</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EMC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="5">
        <location>
            <begin position="103"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="33611" checksum="E287AB900027F91E" modified="2025-10-08" version="1">MSASFGSALHSLANYRAHNTRASQEVLEKGKLLLNSNAASKLGDDAWAFLEQLALAAIDVAKYDVADECIRQLAAKFPESPRVDVLTGIRMEATQPPQIVLKFYEELLEADSSNAAIYKRQISVLIRTGKIEQAVLKLSEYLDTFYSDVEGWVELAELYSSCNQYTFATQALSHALLLAPQNPFYVLQFAETAYSADDIPLAAKMFMLAIDIVDRHTSDESIPTGVSIRAWYGVKLCCRVLSERSCSSASETPLPRNLNLLDELATERVLTAYSAGGTDNATGRELVSSWMGPSDRSGTRLHFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIA4</accession>
    <name>A0ABQ8VIA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-dependent phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_827742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF11">
        <property type="entry name" value="METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046263845" evidence="1">
        <location>
            <begin position="23"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="391" mass="43223" checksum="F1B84E35EE79D913" modified="2025-10-08" version="1">MKSFAPPFILAWLIRWIAYGGSVPNLALIPQRRVTENLGILQDPYPDKPRITFRPDGTFKLTVFSDMHWGENPWDSWGPEQDANSTRLMEKVLPSEKPDFVVLNGDLITGENAFKDNATLLIDRIVAPLNAAQIPFCSTQGNHDNQKNITHLQEILREQQVAPLTYTRVAPAGVGGVEGPGNYWVPVYEKASDPSPVLVLWFFDSRGGFSYGDNSTAIPDWVDESVAAWIESESATMNDAWGPAENRGALAFVHIPPHLIQNLQARLNSTKEPGLNADILGSGSTQGTTDEDDVGQDNAFWNSLNANVKNLHAVISGHDHGDEWCIREPTENVIFCFDKHAGYGGYGDPSWGYGVRNLVFSSTEPKGGVQTWIRLEEGEIRANVTLDESYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIA9</accession>
    <name>A0ABQ8VIA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_292060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="132" mass="14681" checksum="942A42FE0E04CC87" modified="2025-10-08" version="1">MHIGAGVCFISIRKKSTVIGHLNGKIQPGLSTNKTETCKVAPPFTVALGKVGCDDLEEGRASVLSWDRKHFRGKEFSRGLTRLVPAKDSAYQINAAFFFPSVIESKYLYLQSTSSRTYPMCIQIIRRIVAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIE6</accession>
    <name>A0ABQ8VIE6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_293191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046574849" evidence="2">
        <location>
            <begin position="20"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="201" mass="23084" checksum="8D3B19C7031F9424" modified="2025-10-08" version="1">MRFAVWAYFALFLLSAVYAAPRFNARAGSDEGSPSEPPSKKIKLEPGTQAVKQESPTVKSESVSPAPMNPREVVHISFIDKGKLKGEHLFEFEQRDKDLLEALIRRAAGEKWGWTEDRSQNMAFEYPELTRHYTGIRKRYFFTGPFQQCGERDDEECIAELIDFYDKQDPPRGEGSIYLRKKGVKGFIYDKGDKIFSTLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIH3</accession>
    <name>A0ABQ8VIH3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_294899</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22585">
        <property type="entry name" value="Rcat_RBR_DEAH12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="402"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="858"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="297"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4495439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1073" mass="120386" checksum="00FA4DA195204012" modified="2025-10-08" version="1">MTPISKTSRTISTKEAADSSNIVMSSSCKYRPIKSNKEAIRSTHGNCKPTVVTSTGTMSNKSDDGVGIYINRFGKSQVVAQAQKPVLLFGSPKEAGEIVNPARNPDKVQGPDHPFGSPKEAEREIVISTCLREPEVCRNFGSGFCEWGKKCHRIHHFDTRNKVNRRILQNVFKDDLPQVALTKANINEACLLYMEGRCKLYRHCYRIHLIPPSRTFTDAGAASDSPESELIDDPIVVLPPPSKPLLPPTIYLDVPNDNQLIPSLSGQFMPYLGSHLSLKASELPELERWGCETEASTWLDTDSDTSEGSKSSDSSISSLEASAQVKHPPPKNSETCRRWLKGCCERGYSCMYVHKDLEYDEPLFEPRPAAPPFYMATIHDHIRVKFGAGFGVQEVITGFETPWLYVNNIPYNVSQDEVTQLLSKHGTVQDFRSESGNQRGTLRVRVRFSSDIEARNANIILNGTRQWGSLISTQLPVNTAHGRGATLQNTAVRIEWEAPSIIGYAGYPTEERAKEAIAIAKTAYSETYISAHMYSGLPQMAAYTVRFLNLPVHTKKEQMTKYSKPLDMMWDVPNYTSVDEVAIFLRRKLESNGIDIINFELLPPPYRDGRVRAWVHFPTPVAAKAACQHLHLRKPMCTGRTRISAYHMQSLSYSIPLEHYKKIQDDILLFRERLWREVLGTTCTIIPGAPSVTIRLSAINGKDLGNLKAEFEHLRGGEVVKHDGEVLWDRFFGLPAGKSYLRKLEIAHLGIAIREDAMRRRLTLFGQSALREVVKAALTEKHNELLVAEKRYIFLGPLIGPFIHSELESLSQRLGSEKVVLDMWNRQLVVSGKDHDFRVALQAVQKIQRRQHPHLQRDVASCPVCLGEVDCPVTLPQCKHSYCRACLISYLQAAIDGKFFPLTCLGNDDNCSSPLSISLARQVLSSGEFDSLIEAAFEAHIHERPEEFHYCPSPDCMQVYRPAPSGNILQCPSCLLRICPQCHVEQHDGFECPDRDGGDHLFNEWARTHNVKNCPSCRVPIERAEGCNHVTCIRCRTHICWVCMRTFPGGDGIYNHMRAEHGGIGNAFDDDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VII4</accession>
    <name>A0ABQ8VII4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_918883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="40838" checksum="1F1119AAFE65AEF4" modified="2025-10-08" version="1">MTSSEHTNSAVDHASNSSMNFHNSNETNDDLLTLPDLHFSYRKTSVALYVAFLIICNVVIPCLLFYLLQNFTNITTKELIGISSAALGISSCFDAPFRLFRLVKHARTYGPTDVWWHLDFVMWTYTFALLVFAFPLAIAPAIAFYNFFLMSTMMLVGPVGVVFFFSLLAYHYQWRLPVRCSSEPVGSLMKPAVFYCLEDVGAVDFMHGRIFRQRVHRRWDASPPFRQLMTELTIYWVISGAIYCGLTAAVTWAATLNFAFGWVLGQFFIWAFVSWVGCHFLARRGLKRERAYWDDRGRTLFKENTGPGGINEGGEQEKPPKRSRSAPGHVNDSASADTSTPTTPATRSLNAPPSKVEKTEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIP5</accession>
    <name>A0ABQ8VIP5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="192" mass="21394" checksum="33281C34727C088D" modified="2025-10-08" version="1">MGFVAAEGLWNDVSWELGVYCRGWVEAGRLMEDPGGPGMSEAVPWGVKRKGGRSLRVGRGYGRPTFGVDNLMNPGHDYLPYPMRTGRGRERGIKSGGGGRVKAKRRAASNRIYSPFEEEGSQHVRPYEWFCETLQGNLATKDLFVAEDSAVKAHSPLPELRAIVVLLRRVQENNERGLEAERWAEEGETDSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIV7</accession>
    <name>A0ABQ8VIV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OTU-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_274649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22748">
        <property type="entry name" value="OTU_OTUD6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF10">
        <property type="entry name" value="DEUBIQUITINASE OTUD6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="120"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="293" mass="32334" checksum="4DFDC6DFF7ED3605" modified="2025-10-08" version="1">MGTKKNKLKKAFSPPFQQSPPLPEPDDDAELLNDLMAQLDSGNQTVQAESAQVIQDIQRQETVSGTKKDPKSRYQARQARKAAALAESYSPSNPEADARLMQEAKEEESNIRRICDELNVQIHEINPDGHCLYSAIADQLALLSIIPPAQANYATARLAACNYMYSHPDDFIPFLPSTSGEDGPGALNPGIISPKGFEYYCQAIRDTSEWGGEPEILALSRAFNIPIHVIQSGQPPIVIHNPAGTPNDGDVRDKRAVRISYHRRMYGLGEHYNSLRPQSKLSNISNSIQNILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ73</accession>
    <name>A0ABQ8VJ73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_266430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="67"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="24525" checksum="D5F8E81C7D7E7C72" modified="2025-10-08" version="1">MVFTPDATLIIRSKEYGDGSEYDIGSTSSMIPDHYVKRIWRKPGLLAGTNGTRTVQYINKSPDSSDRSIAYSATETKELLVFRVGGYKNPGEPFAKVQWVPGSGKPTDKSIVTLGNKTGVLKDILKKSNTLSTSRMFVGPDGVEYKWKVIWVGNDPAFPEATFRTLYARHSKHPIATTARLTSRDGLPQDDSYPIYIAEQGLNMQHYIVATLAVLESFSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJA3</accession>
    <name>A0ABQ8VJA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_274584</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="28"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="622"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="655"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="671"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="709"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4495583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="727" mass="81305" checksum="BAB786B342FDA96A" modified="2025-10-08" version="1">MSQPGQDAKFFQRGKIEEFRAELLAAETKDKKFVKRKTVLKKIVANITMGMDMSPLFPDVVQCLGTPLLEIKKMVYLFLVSYGRSKPDQIHLVIPNFLQDCNDRNPLIRALAIRTMSYIPIPVVTEALSDNLRHALKDRDPYVRKTAAICVAKLYSADPRKAERGGFVELLRDLMLDSNATVVANAVAALSEIGDRQDGVIFKLNLATANKLLAAIPESSEWGQIYILDSLLRYVPERHTDAEMMAERIIVQLQHGNSAVILTTIKALLYLMNYMENRQLIDYICKKMGPPLVTLLSSGPEVQYVALRNILLIIQRRPTVLKNDVRIFFCKYNDPIYIKLAKLEIMYRLARAENAKEVLAELQEYASEVDLDFVRKAVRSIGRLAIKVEAAADDCIQALLDLIETKVTYVVQEAVIVIKDIFRRYPGKYEGIIPNLCENLDALDEPEAKASMVWILGQYANIIDNADELLDDLCYTFLEESTEVQLALLTAVVKLFVYKSKVDKAKELVHKVLKWTTEEADNPDLRDRGFMYWRMLAINPTVAGEIVLSEKPPITTDSDRMDRGALDQLLLHTGTLGSIYHKNPETFIRNAAGKALKDSPALNAHSRAVLIPLARTQLPSMGPIVVAGPGPTEPQAQSSPVAPLPPAKTDVDTSALPTQSSQLISPTQDDVANDQDETEEDDEPPHSTQASKLDPYSNLDNAFGGYLADEPRPMASRQHDDDDDLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJC7</accession>
    <name>A0ABQ8VJC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_918568</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051654">
        <property type="entry name" value="Meroterpenoid_MTases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35897:SF1">
        <property type="entry name" value="METHYLTRANSFERASE AUSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="171" mass="18973" checksum="3DBCFA55B73D61C6" modified="2025-10-08" version="1">MFKSTPKSFPVPFVQGDIFDTNFLESTKPFTVQSPSTKPVPALNTLTSLNPLRGHLSACFCGAFFHLFGEDGQKQIAEALTGLLSPEPGSMIFGVHGSRAVKGFWHPTGSERYMFCHSPESWKDLWEGLFGKGNVEVKAQLRKEIGGDDLFGTYPGNKEPYHVMEWSVSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJE2</accession>
    <name>A0ABQ8VJE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_709904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="123" mass="14686" checksum="423FE1F5E00F5817" modified="2025-10-08" version="1" fragment="single">LEPQYLDLLRIWMDYEHKNGWHNPHKLAGFSPEKRLAVLLAWMKNRPQPLPKVNTRGFFTPKFVEDVWTWWASLQPDWRSLDENGLPMPFEDFGHDLARLDKHGKNAWIGLLPCLKWWRVGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKT0</accession>
    <name>A0ABQ8VKT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_880243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047047553" description="Glycoside hydrolase 131 catalytic N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="2">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="295" mass="31794" checksum="252334F2107289F9" modified="2025-10-08" version="1">MVLFTALLINTAIALATASLYWDGRVPQTMTESDLDSSIGPYLTVVKGSEDASHYTTLLGTDSTPTPLWSSVVSEQVVSLTITNSSIFVPGGSTPQNGFRRTDLIAQGNGSNSALDAIMEVGVSKFYFSVQENEHLPLNYSHEYQIVFIEPSDGTHVFELQLGTPFSNPSTTELAADARFLKVRDHALNLLFETPFTAGQWHNFAVQVDWKNLTLQVFYSTGGAELVAVTSVAPNPTAAIGSAGQGDFHAALLKLPLVDPSEPATEQNDVAHYGIQEGTTEGLFYSGLFVEQVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM92</accession>
    <name>A0ABQ8VM92_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_894603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="250" mass="27220" checksum="C828A6E917F48D39" modified="2025-10-08" version="1">MSFCEHCVKGVTHEGEPAGKWEEINGVNSYVATPSKDYPKDKVIVLLTDIFGPQLINNRLLADDFAANGFKTVIPDLFNGDPAPVSAFNPGSTWSLTEWFKSHGPENTRPSIDKIIEGLKKDGVTSFGVIGYCFGGRYTFDLAFDGIPKAAAVAHPSLLKIPEDLETFASKATAPLLINSCTTDPQFPLEAQAKADELLGNGKYAPGYKREFFEGCTHGFAVRGDMSDPKVKAGKEGSFKATVEWMIKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMB8</accession>
    <name>A0ABQ8VMB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rad60/SUMO-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="49382" checksum="D08BB30B36573D31" modified="2025-10-08" version="1">MRLKAIDDAGPGADVPVTIFSLGTKRKFMATPNDYPDLVRLVRRKFNIPDECVPIFRSRAPTSNRSEERFEIDDSAYEHMKGYIDELEIVIDVDAVSRTREETSLEHGGDVKGKMKAKDTPVVSPSSGREGAKPNTKSFNRPPTTVDISRTLSTSSSSVKPKSIPVPPSPRTQTDAHDLFNENMPVEYASPKKKKTTKPQETPNTIPRHVHNVDADEDEVLGTPQPAGSKSKSTNSKGSSSEWEELALQSKSSQEEGNTLGESSKGQKSSHKGAASKIDGEISATVKKEKLAKPSNSTASAKDTRLLARIDAITDSQPAIILTQDPNPSAQSQNQSQTQTQTSTSTEPEPRFKIRIWGPRDQNGEFMTKKKHTVRKVLAGACKNFGLDPVQAKLQLVVELPDEFTGEMVSHHYDCDNEDTVGKAGIGPESTLKVCVLGEEEEEDYEEGSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMF5</accession>
    <name>A0ABQ8VMF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_210428</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF1">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="33"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="386" mass="41724" checksum="06F333824E2E44D7" modified="2025-10-08" version="1">MFLTKQLRLVLQSTIIVAVLAACVGATILYAGVNESGGEFGVFGSPGTGLPGEFGVTYDFITESTVDTFVDTNQINFFRVTFLMERMCPLATGLGSTFNETYFSEYEDAINYITVTKGAYALIDPHNYMRYNDPSSQPNSGSIIGDTTDPNAATTEQFQEFWTELANRFVDNPNVVFGINNEPHDMATSLILQNDQAAINGIRSTGATQLILAPGNGFTGGHSWTQVTGANDDPSSEWLNQIVDPLNNTAIDIHEYLDEDFSGSHDTCTQPGPTNLAALTTWLQENNLKAIVSEFGGSNDPTCLELVPQLINYLSENDVYIGWSAWAAGPFWGTNSPCCGPEVGSLEPGQLDEEGGPNGYTTVWQAVIQPNIDLSDLKRSGVSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMW5</accession>
    <name>A0ABQ8VMW5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_820836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="39991" checksum="84E2BDF5D4693F2E" modified="2025-10-08" version="1">MHTSTLWNSNSVFTEPMLIVPLKTPLPPLPTEILTHIFTLTTTIDSGASIRSLLRVSQIFHDICAPLKYHCLSLTTGSSIEHLHQELKRLENSPAHLRRILHLYISLSQSDIQGDTECDTISHIFYILQSAAETLKTLTFIYHNTVFSTSVLGQLLRKSFPVLTELTIHGFYPFPSPMPPSELPSLIEMNKSFMPMLERLHLSGNRNPHGLLQLSSLDECFPSLSHLRISGLLMAGSFVEELKGALEEHIAYDDNPKDPYNTPTYIKAKLPSRLRCIVLQPGFMPPSSRPGVAGSAVQKNSWMMTRLKDIEEAAKRRQNVLVTLKARMQDPDKVPVSSVLHRDWFGRMNGDEGCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN26</accession>
    <name>A0ABQ8VN26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">4-hydroxybenzoate polyprenyltransferase, mitochondrial</fullName>
            <shortName evidence="8">4-HB polyprenyltransferase</shortName>
            <ecNumber evidence="8">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Para-hydroxybenzoate--polyprenyltransferase</fullName>
            <shortName evidence="8">PHB:PPT</shortName>
            <shortName evidence="8">PHB:polyprenyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_825050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate = a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:44504"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
            <orientation evidence="8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4496860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="332" mass="37657" checksum="CC1A4BCA1242F3B6" modified="2025-10-08" version="1">MSSHLNEKLTLDFTQAEFLDIRRKPLDVFPSVLRPYLELIRLEKPTGTKLMFWPFAWGLTMAAYSVKMHWTTYAFRLMQCLLNAFIIRSSACTINDIFDRKMDAGVERTKNRPLASGRISVFAATSYALMQYAIGTAWFYLTVEDLALSVALVQLLPIFAIYPLLKRVTYWPQAWLGFAMNFGLITAWVSTTNTFDTPILVTAMAACWCWTMLYDTIYACQDIEDDVKMGIRSTAILFGSYIRPLLIACGCSFVVLLCGAGILNGQGPAFYILSVGGLLLHLIRQWWTVDLEIPKSCWANFNSNGQLGWIIWLGLVIDYAIDLRLIQANLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNU4</accession>
    <name>A0ABQ8VNU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_866310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="177" mass="20095" checksum="392BC36AC7DD0B59" modified="2025-10-08" version="1">MADNDFRKLLESIENLTETIETDSNDVRDSEEQKMVSVVEQVQGGELQLDKHQVQMAGLIEASQTNLAQEMARAMEALPSLPDWKIHFLNILLSKGTHAEVTRMLAMNIFAPEQILPCDVQDPSKIIESLRESLRNEESVDPADTLVDRLELYRASQRSSIVMLERFLQSVVELLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP36</accession>
    <name>A0ABQ8VP36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_758038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22278">
        <property type="entry name" value="DPBB_GH45_endoglucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22514">
        <property type="entry name" value="EXPB1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045711205" evidence="1">
        <location>
            <begin position="25"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="2">
        <location>
            <begin position="48"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="223" mass="24165" checksum="E58B1E7636B23A21" modified="2025-10-08" version="1">MALLFIPSFFQIWFFSFFLLTVLASEWIEYPSDGFATLTHYSLPLDYIASCGCTADSTHYPTAALSQMAYGSSTAYGPACGRCFNLTLLHTFLSVPPFYPPNTKSIVVKVTDLCPLSTTGWCNATTNGPNAAGNFLNFDLAYPSTSIPSDFFPSNATYYGYTDFGVWNISYGSVACSNWEGWNNDAALGSVTGQGPESVCCAADPTVCPPYCCGYPYSSTQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQJ0</accession>
    <name>A0ABQ8VQJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_820803</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045047">
        <property type="entry name" value="Ard1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091:SF4">
        <property type="entry name" value="N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="158" mass="18039" checksum="9683FB0580181CAB" modified="2025-10-08" version="1">MNIRLARPEDLSGMQAGNLVNLPENYLMKFWMYHILTWPQLSFVAENDKGHIVGYVLAKIDEESEEKGGEMHGHVNSISVLRSYRRLGLAKRLMMLSQDAMASVYKANYVSLHVRKSNIAAIGLYRDTLGFEVAEVEKKYYGDGEDAYVMKLFLKNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR59</accession>
    <name>A0ABQ8VR59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxidase</fullName>
            <ecNumber evidence="7">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_816755</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF53">
        <property type="entry name" value="HEME PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 7 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="8">
        <location>
            <begin position="69"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="546" mass="59375" checksum="D00BCAA7F93A7934" modified="2025-10-08" version="1">MKLNPNCPKLSYMVQSFPLLYTRVNIILTLIGYAHSFSTFQWPNPQLRYADNQLYEGSMGILVQDCPSRENTTIPAQWLRIAYHDMSTHDIDDGSGGLDASIQYELDRPQNIGQGMIDSLNDFKAFRIATPFFGMADTIALGAVFAVAGCGGPLIPFSAGRVDATEPGPETVPEPQQDLASHTEAFRRQGFSPTEMIGLVACGHTLGGVRQVDFPLIVTDTEDVVQSFDTTTNFDNAVVSEYLQNTTQNILVVGPNVTTRSDFRIFASDGNVTMQSFLSSDTFAETCKDLIGRMINTVPNGVTLTQPISEPFDYVVSEPLFSYRNGTLSMATTLRVMTENPSRTVTMLWADRQGSSCPPSGCTSPSISTQEVVFSLIGNLQGLTGTRYSFNATINASTSISKFWFEINENDGSDPIVVDNGGPGFVIEQDSVFIDNSRSENVLLSSSFDEYRKVVVAVRGDTSSSVSITTSDPNSDASAPPYLLTVITTNLQLDDSNPSEGGFTFFTVNISETVNFVSISGNIGGVSYVQENFDMTVVNFAFVTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRZ6</accession>
    <name>A0ABQ8VRZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(10)-N(2))-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.214</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_166668</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.214" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016691">
        <property type="entry name" value="TRMT11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00507">
        <property type="entry name" value="N12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51627">
        <property type="entry name" value="SAM_MT_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="11">
        <location>
            <begin position="192"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4498255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="469" mass="53989" checksum="CF23AF7515A27B72" modified="2025-10-08" version="1">MSKYLVVFAQAHQEFRVPELESVAQLNNFKISLSDEPEERDPSRPFMIIELESENHVRLLAKRCILIKSIYEFYGRGSTYEELHIRNRAKRQMWERYIPETSFKFIVAAYNHKIPQHRQKEVVESFAYMGFMGKIDMKTPEITLGCFEEYATRNGQTRERHEGDGDFLQVYFGRLIEEGTARPLVQLFDVKKRSYFGNTSMEAEISLLMANQTLACSGKLIYDPFMGTGSMAYPVAYFGAQVMGSDIDGRQMRGKQTTPGVFRAASQYGVTPRIIDICTFDVTNNPWRCGGLFDAIVTDPPYGVRAGAKRLGRKKELDADRLALYHEHRTNPRPDDSPYIPPTRPYELSDLAVDLVLLARYLLKPGGRLVFFLPTVTDQYEEVDIYTMLCDGMEVIANSLQDFGSWGRRLVTIHKVTSELYPPPDFSIRDPEMKDETQRVPAHRHFREKYFQGFKKTEEVEAANLSHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT46</accession>
    <name>A0ABQ8VT46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_916150</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF11">
        <property type="entry name" value="CERAMIDE SYNTHASE LAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="12">
        <location>
            <begin position="171"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="398"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4498645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="421" mass="50269" checksum="1764655B7A755269" modified="2025-10-08" version="1">MVKRTASTSMITVLRNFEQDPAHHLAGPFLPQTPIGSLTPKRSNSPDIRRRHQPRAVDPFLRWAVVPVASLKVLLVPIILYANWEFVYPILAQSIPRGNTYLSSDIPNPFAQFFLLSHPVPSLDEENLRYQKGWSDLLFIAYYVVFWSFIRQSLSFYVFQPMARYFGIRKHKLDRFAEQGYAMLYFGIMGAWGYRIMGQLPTWWYRTEAFWIDYPHWNMIPELKRYYLMHMAYWIQQLLVLVLGLEKPRQDYYELVAHHIVTIWLVGWSYLINLTLIGNAVYMSMDIPDAFFAFSKLLNYLRAERAKVVSFIIFIFIWTYFRHILNFYILYSVWFEYDLIPDSSKVWIWTNGTYLNWWMKYQVFTPLLLLQFLNLFWYFLIMRVLRRAIVGSEVDDVRSDDEDDGEDEDEDKPLSQSKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT90</accession>
    <name>A0ABQ8VT90_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NUC153 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_754126</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202:SF0">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25121">
        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="7">
        <location>
            <begin position="165"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="6">
        <location>
            <begin position="600"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="401"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="633"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="481"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="638"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="680" mass="76692" checksum="1CF6853311A4A6EF" modified="2025-10-08" version="1">MSDPRFARLKTDPRFRRPKKQQSKIVVDDRFKSVFAPSKNKKSKGKSGRVDKYGRPVSDDHDQENLRRFYRLENEESVESQPSALDYARGEVLLESSDEEEEQNDSDEEDTFVTVGQDSSRPISIRNDEAEIDLNETNFEDLDAQAAAYNESNLETGTIPEATRTNRLAIVNLDWDHVRAVHLYKICSSLVSPTASVVSSSSKTSFGSEKRQRNVKSSATTVVRGRVLSVKIYPSQFGKERLAREEKEGPPPEIFKRKEVNDDEEVTDQNIIQIGDENEFDEDALRKYQLERLRYYYAILTCDTVDAASHIYDELEGTELERSANVFDLSFVPTDMTFEDEPRDEATEDEGSAYKGVDFVTDALRHSKVKLTWDDDDPTRNQMTRRKISRKELEEADFKAYLASSSSESESDNEDKKKSGSRDRLRSLLLGGGNDLPEGWNDGDGGGDDGDVDMEVTFAPGLSTTNEDKEETTLEKYQRKIKEKRKKKKEHGSAKAAEDEKQVVGADDFFAAASDDDGEIISSDKKSGKVKVKKSKTQDVATENELSLLVGSSNAEPQHFNLKSVIKAEKLKGKNKLKRGKKKELDEAELQEDFSIDVNDDRFKAVHENHDFAIDPSNPQFKKTKAMKTLLDARSKQRMNSSDTQPQDESSGQSLQSLVASVKRKSTSSVTPIVGKRRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTH3</accession>
    <name>A0ABQ8VTH3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Minichromosome loss protein Mcl1 middle region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_876367</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="9">
        <location>
            <begin position="9"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="9"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="417"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="8">
        <location>
            <begin position="723"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="837"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="837"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="993"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1006"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1061"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1072" mass="118462" checksum="94BF9A96C38C518D" modified="2025-10-08" version="1">MSLPHIIARKAHSDGHTCLAFSSDGTHAFTGGSDCAVRVWKAAEGAEQEPGNATDAEQPVTTLAASNDCWLSGSEDGFVRRYIKDKDELHGNITEEAALAVRCIALNEQGTRLAVTSDNPSAKVIDMEDTLKLTTLHGHRHNVRRASWRPKSSILSTCASDGEIILWDLSGEEPMILHTLDNMIPSVTDPRAPGFLHDCSVIWHPSGEQFYVISRTHDVISISGKDWTQSGKFVDKEVAGTTTALAISLNGAYLATACQSTVYIWTTDKRQVIAKQSGTSGAVITQLAFSPKEHLIAWTDASGNFIRWREPIPSNLPSSIKRISPATTATSKSISGVPQGVDLFDEDNGLSLDDLEGFEELDDPTAGAEGGDGFNIDDADFVIDDVGGYLEDKPAMSRGNAHGLVREMVSITKAQPAFQPGATPFQGNKRYLAYNMLGVIETTRSEQEEYNLVSVDFFDKSARKSYHFNDTHKCHHAYLGERGALFASDTLVLYKPYGSWTTSQNDWTYSLTKTNTKVLGICAGGMTPSRSFKNNTDSDLMGFGNIVVATSEGHLIVLSGTGRERRIIALGGDFVTMVAGDEWVLVIYRPGATTIDGSQSLCYKLYHFDDLSVRQRDELPIPKGHTLKWIGITQEGAPVIFDSSGLVHLVVKHRVPHHATWVCILDTNLLERRAGKDESYWPIGITGNTFMCLILKGRQEHPGFPRPLVQELPLRMPFNTQNEKEEEIERELLFKELAMESLDGDELTTDNILSKERAIDKELVVLIQGACKEDNINRAVELTKLLHNLQTFDIVAKIADFYHLVGFKEKVIVLKRIRENSEDRFEAAREKRRRWNKIDTRPQRLPDVDSNDSVSRPKAFQDFGPPPAIYRPGLTRATPSVEGTKFSSSTSEPPSGDTWSDPLAPSTNAPSSEKRKRIEFEDVEMESQSDIGIPMPPPKQKTNPFARKPAAETNKNPFARKGGNKTILQSESFFEKVDAAETTPAKAKKKINKEKDKPSEKKEGPRQQTLFGLFGANQNGGDKKSSTRRKTGLTPPPDEPESQASDITMADASQIETQPDGWEETQLIDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTN0</accession>
    <name>A0ABQ8VTN0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_817126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="33940" checksum="B69EB21D21C95A6C" modified="2025-10-08" version="1">MIHESRATEVGVLLKAPMVKSHYILPSDDPEITRLNLQNQLLTREVCDGKLIFAPAELEHGDQVLESGTGTGIWLLSLAETIPPTISFTGIDIHTRLFPQEFPSNVSFIQRSITNLPAEWTKRFKIVNQRLLIGGLTRKEWKKAIQEIHRVLVPGGWLQCIEPNIPLKTDIGPHTERMFAAVRDLLAKNGLVHDIVEVLGRKLSKTGFTNVQTHTVSLSAHRHEEEFNHRTLMEWFFLALKPGILAQKLLQSEEEFGELMQSMLKEWDESPQVAWSWSVVYAQKRENNVGTAKFCVYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUG7</accession>
    <name>A0ABQ8VUG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMMECR1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_812932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="entry name" value="Hypothetical protein ph0010, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00296">
        <property type="entry name" value="TIGR00296 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016:SF0">
        <property type="entry name" value="AMME SYNDROME CANDIDATE GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="AMMECR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="AMMECR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="14"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27498" checksum="56498F9A60F3B2C7" modified="2025-10-08" version="1">MSLVPPDPAADRPKLVESEVCTAEHCFHAFDALYCALTPSAIPITPTFPDEKYPLFITWNTCRPDRPPRLRGCIGTFEPHTLHAGLAEYALVSAFRDHRFRKISKSELPTLECGVSLLTDFEDADSYLDWTIGVHGIYISFPHPSTLNSASSGAPSPLSSSSYLPRITSMQTFTATYLPEVMPEQGWDKIDAVDSAIQKAGWTGTITEDIRRSVKLRRYQSRKHHVDWDEYVAWRNEHGPDFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUX8</accession>
    <name>A0ABQ8VUX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial</fullName>
            <ecNumber evidence="9">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Succinyl-CoA synthetase beta chain</fullName>
            <shortName evidence="9">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_815758</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 11">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF1">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="31"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="75"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="350"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4499019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="399" mass="42910" checksum="980289509D86214F" modified="2025-10-08" version="1">MLSSLRKVGSLARAASAGQKRSLSIHEYQSVKLLNSYGIPTPKSIAASSPQEAFDVAKSFGHNRLVIKAQVLAGGRGKGKFDTGLQGGVHMVDSPEQAKEYAEKMLGSKLITKQTGASGRICNAVMLAERRDPSHEYYVAVLNDRVTQGVVLVASAQGGMNIEEVAAKDPSAIITTPINFNTGLTKPEALAVAGKLGFKDSAANEAADIFINLYRIFKEKDATQIEINPMAETTDGKVLCMDAKFGFDDNAEFRQQDVFSLRDVSQEEASEVEAQKANLNFIKLDGSIGCLVNGAGLAMATMDVLSLHGGNPANFLDVGGGATPETVKKAFEILLADPKVKSIFINIFGGIMRCDYIAEGVIKATKELELKIPLVVRLKGTKENEAKQYVVLNTTRMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV35</accession>
    <name>A0ABQ8VV35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Adrenoleukodystrophy protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_915731</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF69">
        <property type="entry name" value="PEROXISOMAL LONG-CHAIN FATTY ACID IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="463"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="708" mass="79558" checksum="AE761921A99B71A8" modified="2025-10-08" version="1">MAALSTSRIKEFLELLDGISKHYAAHRPLIQRILNISFILYVLGTTYKGFSARPAPKGQLKRNKDAGNEEGMRRPPRVAVDALFYQRLRHILRIVIPGIRSKEALMLIMHSSLLIARTAISLYVAALDGKIVASLVRAKPLEFAYNIIRWLLVAIPATWTNSWLSYIQSKLAIAYRTRLTDLVMREYLGGKNEAGPEGKVYYKISNLDDRIKNPDQMITHDIQRFSASLAAIYSNLAKPVLDVILYNYQLSQNVGAEGLIGLTILVQLSAALLRSLTPNFGSYTALSAQLAGALRHSHSRLAEFSEEIAFMRGEETEKMLIEREFATIILHERRVLRRRWWFGCVEEGIVKWLWGSFGLVLCAIPVFFKLPGADNIDLGGRTEGFVTNRRLLLSSSDAFGRVMYSYKDLSELAGYTARVSALLETMEDVKTGKFAKALVSSASTEDNAKILQGRGEVFISEDIQFENVPIVTPNGDILVRSLSFKIQPGQHLLIVGPNGCGKSSLFRILGGLWPVYGGVVRKPPASSFILIPQRPYLTIGTLRDQVIYPHSQREMTARGITDDDLFKILQVVQMENVVEREGGWDSMREWRDALSGGDKQKIAWARLFYHNPKYAILDEATSLVPLEMEGRMMDHATKLGITLLTVSHRPSLWKYHAMILHYDGQGGYVFTKLDAEKRLALQTEKQALEAKLADVPRMKARLAELKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVJ1</accession>
    <name>A0ABQ8VVJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_812946</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06890">
        <property type="entry name" value="PX_Bem1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11878">
        <property type="entry name" value="SH3_Bem1p_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11879">
        <property type="entry name" value="SH3_Bem1p_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035550">
        <property type="entry name" value="Bem1/Scd2_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035548">
        <property type="entry name" value="Bem1/Scd2_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035549">
        <property type="entry name" value="Bem1/Scd2_SH3_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051228">
        <property type="entry name" value="NADPH_Oxidase/PX-Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706:SF2">
        <property type="entry name" value="SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706">
        <property type="entry name" value="SH3 MULTIPLE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="37"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="137"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="275"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="445"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="530"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="685" mass="76393" checksum="633970C94943CFA7" modified="2025-10-08" version="1">MKSIRKSLNGTKDSLRNQISTPLPLPSVSKPASAVTPPQKVIRATADYRSQAPQELSFKKGDFFYVLRDVDDRGSWYEAHNPISGARGLVPRAMFEEFNKTSVSSRISQGSSLGNISIPTGIRSSDVPLTPKSPTKSQVFYAIVLHDFEAERADELDAKRGDAITVVAQSNREWFVAKPIGRLGRPGLIPVSFVEIHDPSTGRAVPDVNALMDRGDLPKVEDWKRAMFNYKQSSIALGVIDAPAVPNSPFVNAQPPPLPPSSNLSIIEDPAARKQSTPSISSGPDSADCLPEGILLYAEAVSFHYEMEEYWFRVNAIFQPYPPPGQDSLPNAKQLILFRVYNDFYDFQVSLLDTFPREAGRQPPHPRMLPYMPGPAENVNDQLTATRRSELDEYLRSLCDLNKAGAKYILEHKVVREFLSLKPGDVESETEPRMQEIETLFATDDDEQYGNDDEYDEVRDTLGRMKVEDDRKSEGSEYGEDEGYAPSPQRTYDRHPYARVDERRPDDNNLRLHAHTQNHQRNGSTSSFNRTSSPYTSNSRSNSPIPERGESPMLDGEYSSRHSTGKTHNASSPSVSSVRSTNAPTVGRARSHSNANNPPISAANPQTAFVKIKIFDRVADDLIAIRVHPLVTHSELMDKVQTRLGGEVSNLRFRDSMSNAFVALDDDNQLRAWMDGTDKHVLYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVU0</accession>
    <name>A0ABQ8VVU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_914065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF31">
        <property type="entry name" value="AMIDOHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G05840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045440197" description="Amidohydrolase-related domain-containing protein" evidence="4">
        <location>
            <begin position="26"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="5">
        <location>
            <begin position="99"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="367" mass="40574" checksum="39C7CC31E9484C21" modified="2025-10-08" version="1">MPPLQVAFIAAVFSILLFNNQHAEARTIHWYDTGNGSIALEEAWSVPELGVSLAAPPLGQTSAELNANLLDIHNQRLAHMDATQVDFMVLSCASPCIQGISDPSTAESTAVHINNELAAQISDPSAGNSTGRFGAFAALSMHNATAAAAELRRTVEELGFLGALVNDYQQSGTNNDTLLFYDQPEYDIFWSTVIELDVPVYFHPRINVAPISTLLYTQAPWLRGAGQEFAVTLSNHILGLCTNGVFDRFPSLKIIVGHMGERIPSDLDRIDKEIARQKVLGMPMLRNVSSYFETNIWTTSSGSFSPALLEYHKEEIGLERIMYSIDYPFETMEDGKVFLDELEDELTEEELRKFTRETAIALLKLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW63</accession>
    <name>A0ABQ8VW63_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mediator complex subunit 12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_751939</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019035">
        <property type="entry name" value="Mediator_Med12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09497">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01281">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med12" evidence="9">
        <location>
            <begin position="109"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1504"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1550"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1508"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1550"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1586"/>
            <end position="1604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1604" mass="179376" checksum="6D3B439DE49F505D" modified="2025-10-08" version="1">MPEGSSDSVTPPVFQLHPPEWLPKTHSSADLGYPNFYPPRPGQEEDILSESNVKNGFVLPQIVLAETFSSQSSISENLHSISTINKLEDLLNEVFARRAKQIPSVPSSTFRMPSRVTLNDTKRQAWFDDLANPEVPLAKLGRNVPHGAKGADIIELLYSKNVAIHRAVWFLRVFGANETAGLRNKPSYNPNQYSVEWTNVVTAHLRKQLIDIALPSAPRPGVNIKQTFKGVLSDPETRLKWISRFSYCLELLRVFYSEGLVDKRTFFSWLVNQMCSCNLAQAGFVCRFVDEYFEGMIECRPLARPFVEASLCKISEISTSSAKDYLVDTDYLIKFLLQRVCLVLPDAFVSPRMWINYSNIICEVLTHNPNNNHPDGSIEQLTGTSIFNIIHHNYLAVKRRIEAMLFRNLPSLTTSPHLGSAVHDVELLNSISADTDVANLPFFPSSSENLAGISEKLDALLTWSVTPLQYGDHRAFAAVTLIQKWRTKAGDRANRRDASPPDGFLQDQLFEWLDSSDVAGEPENIAAVALLYGKLVKHELFSYASYIQRLIARGEPGLSFTEDIGSRHRNYLRWVPLYNTTPSLTSQRKVVLYGVRARETPEDLNEREIRKEIRAVLPELFGNPAEIALPSPTSLLSSCRLLLNSPRYEQVRTFGTWLMPVLQKAIEFDVSHSGILKSFNVAVELMTQTDCFDAMLDLTIYMLEHCSTEELLLAVIDTFRRHAVIWASMDVKGMIINALDSVHYSWKMRGIQSKPLLALLVEFDGGRYLSDVSREEVRTDLAAFTLALQPIAHHPDSVPDVLPEILLLVGNPAPDAPSLLANGLWIKYRMSLNWAWKVWDNTIASLRQIPTVTLDIKERRSCALRYGIFLHHVNRHLATGLDDHVLGWFLGRGKDEVAVLSQDVWDIVKVVLLYLVVQGALRTTTILEGLVWPAWLLAASLPDDRGPAPNVHLGAANDLCRRLLLTEDCSSDMIPPTNLLEVHCIRTRRQDVYREPYFPSMIAKIPILVSLENSNRVSEQLRQDAQEIRQLLCEDKLFRQGVFRNLDVVRVAFEQSMQIAEGNGENIFKPTIAALSMILGENTEELELSHWPDSASLLSPWKISATAIQLQFVLRQMGRDSAVGTRGSSDSAALDKLTTMIFHHTLSCEEASFVAQMTKGVGSEIAGKFINNGLKHVAEIIQNIEFSQESMQTSLGRAGELLRVLTYVAEPLRDNPSELPMLDATIQTEFFEAISAKFAALVNLLQPPDVDSVDGEPLMNACILLARFLQFDLAFRGVWTEAVKDASKSLSSNLFILLQIYASGNNCALIAYPLLLDTLFYLRDEMPIESKMGVFDPFQHYPDIAASSLPSDIPPEYRKKILSILPELPGVESVRNLSNAHRDANGNIHIDAPVVNRPWEWTENLGDSIGDYSQGRDVRNSGSLNLLNFGARLTGEVRIPEVYQKDVRIEENLRTFEDGFSSESIFQRDWRETRVKPSVEELLGAEGLRTRLDENLPMSFVAHRRKGSPAMSNSGASRSSGMSMRHSPGRGALNRRSSSTISDIIDVDAIPSISGGSSSRGKRKAAVESDDDVVFVEGPIAAPTKGGKKAKPSKTQTKKSTKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW98</accession>
    <name>A0ABQ8VW98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_810546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="71771" checksum="9DB9C40DA55128FC" modified="2025-10-08" version="1">MFYVAILEARPSGRLQYANRFPLVEACKPEKTLQWLSDNLKTTLALSGHLIFYKLKQFIAITVGGQDVKLKCEPFINEDTLNIFGTPAFLKSTFQDLHLDHLGDTEQECICLVAIWTPSSDEYNSRATASLLPISEDNFDREAIIRAAQSRPPPSIGAKSTELISTQTEQRPDAAYNYRPPELAPPPLAIYHPVFARFRHSMAAPTETLEFTSQELDQASTFIDVSLRHYPDETSRLNALQAVITCSGQKFWGERIILVDNGKKIQPDGGLTISIRDLPVLYSTLGELKNGGGDGGCDTSDQAQCAYMKVVSSPQYTRVREVSCCPALLVGLSGHVMAVWGAAFADRFFFERLSLVFVGPQPDSCARSPTSGRSDLEVGIRMVAKLLRTLEVCNEELKTHYQNLNLPRLSSLGASTSARISQSSGRAYRPHSPNRLQSGDPSRFVHWKSLSCGGKEYNLEFHRRLTTYMDKTVFLAAMTLASDSKIPPTNVVVKFACRYGETGHRLLAEAGLAPRIYYCAFDETIGLWVIVMDYVEGVVCKGKLVGGEAKSLTRAIKLLHDNDLVFGDLREPNIIISKPRECVCVVDFEWCGPCKDIKEGGNVVQRRTRYPTNIALSAEYNWAPGVEADRVIAKEHDNHRLQMMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWB5</accession>
    <name>A0ABQ8VWB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein subunit S8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_816564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="153" mass="17451" checksum="68D91ED3D114F5E5" modified="2025-10-08" version="1">MLPHDLCSHVQNAFRARHAKMFVEHNTQNLGILSILLRAGFISNITRGTITSPDPIAFHHVPEPQQRIWADLKYRNDIPVLKNMELVSKPSKKVFMDLGEIRRLCSGRRAGSVPPLGMGEIAVVRTRNKEYQWLEAREALQMKLDGEVVCRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWI2</accession>
    <name>A0ABQ8VWI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_484362</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044966259" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="525" mass="58278" checksum="407DD03E692F731E" modified="2025-10-08" version="1">MRLLDFIYATLVTLFAARGVLGIGGANPGFEESQQIQRDQLKRMRDFLGPNNDFLSKRQAPPQTINFSNPAAQQFFVPGTSLPDVNFDAGPSWSGLLPISSDPNETRKLFFWFWPTNNITNGDKLLFWTNGGPGCSSLEGFLQENGPISWSWGQSEPTPNPFAWTNLAHMLWVEQPVGTGFSQGTPNITNDDELAAQLVGFLGQFLEVFSELKGKDFFLSGESYAGFYVPYIANFIYENPDLLDLKLKGIDIADPSLSYDVVQDEIPALRFAQAHADLFPFTQAQWAEFQNISDTCGYTDYLDKFVTYPPAGQLPFPAGVVEGTFGTLKPGCRLHSPIQQAVGVLNPVFDVYRVSDTFPSLWSVLGFPESTQQFIYFNRTDVQDAIHAPHINWDICSEGSVYVNAAGRPGNDQSVASMLSVFPNVIEKSERVVVVHGLADFILVAEGTRIAIQNMTWNGAQGFQTPIENETFTVKNFGVFGNEHTERGLTYLEFYYSGHMTPQFVPWAAYNAISFLLGLQDSPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXC8</accession>
    <name>A0ABQ8VXC8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_278789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="547"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="501"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="668" mass="70903" checksum="541DE9FAD2E54A3B" modified="2025-10-08" version="1">MFEDEAQRQLEASTTIMPIDKADSNGTNHAGAKTESNLRDNNGRDSPVTPPSLNFDDSETKLSRKREREVSLEPATGSSAKSNTVSDSMLHNFKEEKDYTRTPAKKNRIHRSVELGATAEEEDSQASGHHRSRSNSSDDSNTNSPPLTQADLGIAASPPQEMKIKVRQISQGVEDLTWRNMKKQQKGPDVDESDAQSQKIPELPMASVEEDRNMEEEALPSTSSSTSASRRASDANPTVEAALHLKRKYPERGPSAEPPSELESNILSSTASMAGTGAEASAKRPRDDPDKDDNPRVPKRPTPPPEEKEKLSSTKQASSSGFMAYASTSSPFASIKGQNIFSSSANSVSSSAIKTPLPSSPVLGRADVLPSAGTKRTGFEAFASSSSPFASVAKSKSPVLGGSGTFGSTNILGGGARAKSPSRRAAGSPSRSSHSSTTTTSVFGSSVGSNSKGGSSAFTVYASGGVQSFALPLTKRARGAGDFGDSSTLGGSALDGHDVFSPSRGEGSSRSSSSSDVASFGAKLRAAGKGSDDEEVNGDEEWDEARPKVNLMSTGEELEETIHQVRGKLFALADGAWKERGTGQLKINVRAEDGGGARLVMRKEAVYTLLLNVTLFSGMKCTLAQDPRYVRFSVIENGQQTTHYNLRLANAKIASELMEAIRENLPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXL2</accession>
    <name>A0ABQ8VXL2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_913623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="19225" checksum="3A57E7686611338D" modified="2025-10-08" version="1">MSLTYLFGAFASNLTTDAVVPVSGTNMGSIQLPNGDTRLYYQDQHNGSIIEMVISNAFTIGVFEESAVLVPASQVRSNSPVAVSLVADGDTFVQVHTFFFSPENVLSQYYWDDVLGIQGGANCLTCVTNKGFVGVAGSQMLYAMASSATSPPTLRVGFVSAGAPNTISEAVNTGSGWSVASLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXU6</accession>
    <name>A0ABQ8VXU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_749631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="9"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="347" mass="37959" checksum="F2F0652456CC6C43" modified="2025-10-08" version="1">MKAVFTIAGARVQVRDTEIPIAKEEQVLVKMVAVAQNPTDWKTIKLARVVGAIVGTDYAGTIAGVGPGVDDEKYKLGDRVAGVLHGSLNKNGAFAEYALVPVHSLIRIPDSWTFEEAAQLGVGTTTTCQCFWQSQNLPKPFERPSSPPTTVLIWSGASATGHYAIQFAKLSGMRVITTSSPKHWDRLKALGADACFDYNDPEVSEKIRAHTENKLKYAVDCFSEKTSFQKVSDALSEEGGTISCLFPSPYKLRAGIKLKFTLAYDLLAEPYKFPKVYNPRAEDKAFGDWATDLVSEVLKSGKLVPLPMKLYPNGLASVQEGLRYMQEGKVSAEKITYRISDTPGIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY54</accession>
    <name>A0ABQ8VY54_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_913293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="22742" checksum="8785F1BE2B8340B4" modified="2025-10-08" version="1">MRPNAPPFLRYCQKLIDKAYNYDHRPSDHSASNAPDQSSVTPDLIASNFTLTPKMTIASVPELTNLLGTEPFESFSRIPASKGDYTIPIEGALGNSYICFHPEGDYHPGQQWSAGQIQHIFRQKNNGPIQLAVLQSQSVHVEDPFSDFWGNGFEVKLVSSKFVDILKVIEMKQVAAHTARWAISNELVVVVNLYSVRRTVEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ78</accession>
    <name>A0ABQ8VZ78_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_610454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="202"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="395" mass="43114" checksum="5131F069BEBC09C7" modified="2025-10-08" version="1">MGAVSGNWITHLLLKRTLTSSILTPYTMSWNLNGLTFAINVGEIYGGMMVGLLLAALLCGTASIQAAIFFCAKKTDPTSNKISVGLLWVLDVLQLCFVFNSTYFYVVDQVGVSSPPFIWSFQIQIFMQTLIMSSTKLLYTSRLWKLKHLVSKWVPIGLIVYLSIDFGLGAAFAYEVFTVDVLPELTAVAFKPIVVLSMCSTSVSDLLVGGTLLYALAKSHTDLSWTSSSGTMLVAYLVNTGIITGIFSVAVVIAFAIGVQHPLYIVSEIALPQFYINCCLSMMNASVYFQTDQASKVPPITHILPYFNGDDPTTSILLGQSPPNSSSRLNLKLTGMATSDMNVPTINEIGLPLFQEENKPEPIVHQMPVEVVIQRAHHAITSDLRRGRGTVVVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZM2</accession>
    <name>A0ABQ8VZM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HRQ family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_17267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021848">
        <property type="entry name" value="HODM_asu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11927">
        <property type="entry name" value="HODM_asu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="45387" checksum="7CFB8409CDAC4DED" modified="2025-10-08" version="1">MDEPQLFLYGVCFVTVLLAVSQFGKSFLDKVLGTFRRRQSIDYFKLSGVPPPKPLLDFNVDKAQARPYRPFRWSYHQTMSLKKMEPDYWLELESTYKERIAQRKALHAKHGKQIIDALPGSELACRELMEMAIQFLCVRYPKQFHFDGRTLYNRILDTKSKVDEEDPLVVLNNNVPEDFLLTLPDSKTGLYTMVAGVCCSSIGWNVATKIGKPLKEIHNVVPDYKEKMEFSMDRYFSKMPTDKPIQRGSWGLEIGQPLWLQDGDPHFAVRTTQDPNLKIEDIYLRVDWQTLRRLPRSRSIVFNFKALFTPLSSFRNEPYIPHLVLKVLTEGKKNLMDYKGTWHIEHKVIPALEEWCKEQEEKGWVPEKWEVRTLDEDPYYPGWKKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W001</accession>
    <name>A0ABQ8W001_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ZIP-like iron-zinc transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_752741</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF32">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="36724" checksum="5D98F196B802D3FF" modified="2025-10-08" version="1">MKRDIIDCNSDSQGDAFLGLRIASIFVIYIGSSCGALFPVLARRSKFINVPKSLFEFAKFFGSGVIIATAFIHLLSPALDELGSPCLSEAWSEYPYALALCLLSIFSIFIIELVAFRWGTALLAKIGMHHDAHGHDTGSHAAHGPEGNISNTSKDVEAVPSEMTSAKTEVHQHPHMILDSVISQVIGVAILEFGVVLHSVLIGLTLAVNEGFKILFVVIVFHQTFEGLGIGSRLAYMNLPSRYNFVPITGAVVYGFTTPIGIAIGLGLRTAYNPNSPTASIVSGVLDSLSSGILIYTGLVELLAHEFLFNKEMMECSNARLTYALGSMLLGCGVMALLGKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1N3</accession>
    <name>A0ABQ8W1N3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance-associated ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_805574</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF415">
        <property type="entry name" value="FI20190P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="983"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1072"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1160"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1257"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1285"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="295"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="678"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1038"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1355"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1473"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1477"/>
            <end position="1498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1657" mass="184560" checksum="3D92F0B668CB597A" modified="2025-10-08" version="1">MDRILCPGASPTEFSDICIRETWSTFTLTFFVFSLYFFAAPHIFLPQWVTQAARLIKKPFKTFMTIHEAEALSGDDGAELHVEEHVPLWRTLVFAFIGLLEMIIWLATGAYNSILSRPALNPFLNVFAWSYTVARPIAYPSATVPYDLFCIYSLQLFSEAFQLGGMLFTRDAFGIPLPSTDIVALHAVNLSLVVILLAVVLYMPMAIPSGKVNIKDIGQTVTPEDYAPLGSWITFAWVYPLIRKGTITTLNEEDVWALSPTIQSRPIFAKFMSIQTVSLAKRLFWANSLDLILEFLISTLSVFFEFLNPFFLNHILSSIETKDRPQAYVYAILMFLGSVLKSQSDLHHLWFSRRAATRTRSELMAMIYDKALKRKDLSGIVRKEEEKKDDQKEKGDKSKKDSKDTKEKEQVGADVGKIVNLMAGDANRVSMTITAIYMMYNAPVEIVIGLLYLYNLLGPSALVGLFVLIAGWPLNTYLTKRSMEIYRGTAKVRDKRMGVVSELIGAIKFIKFFAWEYKWINRAMDEREKEMSWMLKSRINSIMFYILWSSTPILVSIISFMTYILLGNELTVSVAFTAIALFGMIRTPLNVLPNFVIQVAQTKVALDRIAGFLNEEEVTEQVSSLKKDKFTLQQSRELLNESALGLENATFKWNEVETAKPAKGKQDQTIDGVESVTLQTEGSEIDGQTEEDHQFRLEQISVIFPEDKLTVVTGPTASGKTALLMAVLGEMTLLNGRILMCKDTSTIDANGNMLAISYAAQSPWLRHQSIRDNILFGYPYDEQRYQAVLEACALKPDLEILEDGDNTEIGARGVSLSGGQKARVALARAVYARTKYVLLDDPLSAVDSHTSRFLYEKLLRGSLLASRTVVLVTHHVDLVLPGAHYLVRMLDGRIDTQGTVSDLRTSGLLEDITHEAEAEAQKETQVVVGEVADAEVEAVEGGNGNQVTTENLSKPRKLVEDEKREQGGVKWKIYKKYLQASSYWVWGILLVFVILNQFLAVGEKYWIKVWGEAYNSSEPSTAMIQFAPMHLSAAPEHGLSLDGFAHQASPSSPAMFSTRIAFNLPSVYENPMFYVGVYAAIGVLNALLSVIATAIQYTGALRASRILFRQLLVTVVRATFRFHDTTPQGRMLNRFGKDIETIDSSLAGSLQNVNSSLANFFASVITIAVIFPFFLLPATILGFIYRELSIGYLNTGRDLRRMESNSRSPIFSDFSELLEGIVTVRAFSAEKRFLDNIHTKIDFTTRMWYGFWMTNRWLLLSFDLLGGFAVLITALFSISRPDASSGLAGICITSALSFTMSVYWSCRFWTTLELDLNSVERIVEYLDLPQEPPVIIDSNRPPAYWPSSSKDQILVSVENLSVKYAPDLPAVIQDVSFSLKAGERIGLLGRTGSGKSTLAMSILRFVDPSSGKIIIDGVDISSIGIHDLRSRLTFIPQDAALFSGTLRDNLDPFGEHTDVECLDVLQRVQMTMQSQFPSRRTSRAPSTAATPTSSRPPSIIGVDREDTVSSAGSTVTNMDGKTTVSLDTQVSPGGTNFSQGQRQLISMARALLRRSSIVVLDEATSSIDFATDAKIQATIREEFTGSLLLTVAHRLRTIIDYDRLLVLDKGKVVELDTPWNLIQKEGGIFRTMCLKSGTFAQLEAAAKAKAEETSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZRC8</accession>
    <name>A0A9W8ZRC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">High mobility group box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_529594</name>
        <name evidence="8" type="ORF">C8R41DRAFT_860034</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Weakly associates with the stable SPT16-POB3 heterodimer to form the FACT complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NHP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000056">
        <property type="protein sequence ID" value="KAJ4464758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZRC8"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="30"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="30"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="71"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00064996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4464395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4464758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="119" mass="13440" checksum="7154EA052BCC408A" modified="2023-11-08" version="1">MPKETTKSKRKVAEKSEKGSRKAKKDPKAPKRALSAYMFFSQDWRERIKAENPDAGFGEVGKLLGAKWKELEDEEKKPYVEQAARDKERAEEEKTAYDNKQKNGAASGGSGEDAEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AMI2</accession>
    <name>A0A9W9AMI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_452590</name>
        <name evidence="6" type="ORF">C8R41DRAFT_863919</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000011">
        <property type="protein sequence ID" value="KAJ4484780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AMI2"/>
    <dbReference type="OrthoDB" id="426865at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="40S ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
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        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
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        <property type="entry name" value="PRK00474.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ4484780.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ4499573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="143" mass="15842" checksum="FCC514310C2B3AF7" modified="2023-11-08" version="1">MVSTKAVQTFGKKKTATAVAHAKEGRGLIRINGSPINLLQPEIMRLKVYEPVLVAGEENFAPMDIRVRVKGGGHTSQVYAIRQAIAKALVAYHAKFSDAYSAMELKKKLVAYDRTLLIADPRRMEPKKFGGAGARARRQKSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AP39</accession>
    <name>A0A9W9AP39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L14 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_534878</name>
        <name evidence="5" type="ORF">C8R41DRAFT_921988</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lentinula lateritia</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000009">
        <property type="protein sequence ID" value="KAJ4487293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AP39"/>
    <dbReference type="OrthoDB" id="407959at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4483165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4487293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="138" mass="14731" checksum="1BE8BD654DD5A470" modified="2023-11-08" version="1">MSKPSPPAGTKFRLTLGLPVGAVINCADNSGAKSLFLIEPYGFGAHLNRLPDAGVGDMVVASVKKGKPELRKKTMPAIVIRQRKAWRRRDGVFLYFEDNAGVIVNPKGEMKGSAITGPVAKECADLWPRIASNAGTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AYP7</accession>
    <name>A0A9W9AYP7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BAR domain-containing family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8J55DRAFT_165284</name>
        <name evidence="2" type="ORF">C8R41DRAFT_862739</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000003">
        <property type="protein sequence ID" value="KAJ4493688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AYP7"/>
    <dbReference type="OrthoDB" id="5549748at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07600">
        <property type="entry name" value="BAR_Gvp36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="313" mass="34256" checksum="1ED9AC0BB9A2C8D4" modified="2023-11-08" version="1">MEGWKTLQSGFANLNLGQSANKFTKGFQSSVQATKERLGQVSQDEITELPQEYKDLEARVDALRNAHLAMLKITKVYETEAYDYPVQIQESISELSNTIGTGFQHFAATNLKGTPLSPGAAPTRPPLETPHKTLPHALTRASHTASQLLISTPAGDSSKLGKALAMYAQANETISNARIHHDNAVQEGYLHPWQTTLSTSINVAMKARQAVRTSRLELDAAKQGLKTASPARQEQARLEVENAEDDLVQKTEVAITLMKTVLENPEPLKNLNELVKAQLVFFSTAAEALSGVQGEIEELSVAAEGEYRKSRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXA7</accession>
    <name>A0ABQ8UXA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_783061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="61" mass="6870" checksum="45C320D84A76EC44" modified="2025-10-08" version="1" fragment="single">MIPALQIANHLSERTLHINVTSEYLVRSLCYWAADNAEHAWDCTHSDILKVAVSHLCTHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXS5</accession>
    <name>A0ABQ8UXS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_858896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61334" checksum="BD9B07F7FE1290FF" modified="2025-10-08" version="1">MTEQSSSVHSIDVFAGSSIDSWILQLQRLPEHPLKLPEHILRKIFQFACAPPLPPLTEVVYPEEDDLAGASTADTWMEWLSKPGNSIVHLYLRRTPSNIEPDTRESEAQDPEPNLPRELWLRIFGYACDNPFPSVNSSVGEVASQCIITPRGHTAYILTFVCRLWRELAENEPRLWTHITLSVDNLTSGTPSRVLKIMAELTRLYLRRSRPNPETRVAPPLSIVMQTPHIGPCELNWNCFIPTSCVQTFARDDDVYHKRITQLFVRSEGSLLWSLQMNYHGILPQFNVETEQGQDPPTEDEWFCELRSLVIDCGYNHPRRLFPFRRLPNLESLTIKVVDLAFPPGVNINFPSLQRMSVASNAPSVLNDVYRIAQRSNCHAVELLLGDCSSEHSVVLRNTEDSRSAFHILIPKLRSVEFSLNRVFNSNPLVLTGINTLEVIYSPDAPKSINPDFPLGSFVNWMTHSCPTLQTVCLRGVRCNVGYLRYGDAVILQDVHLFHVYRTDLSSQGLLAIPLELREALSVAPDSPHGHERAEVQLNFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYY2</accession>
    <name>A0ABQ8UYY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_856899</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="4">
        <location>
            <begin position="43"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4466357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="296" mass="32486" checksum="8338DE6C98985170" modified="2025-10-08" version="1">MSTWHNGKIQQATPERTAEIRESLTEIRGRVSRAVDALGSVSNIPKLVAVSKYKPSADILVCYELGQRDFGENYVQELVDKAKELPIEIQWHFIGTLQSNKAKLLASIPNLHTVQTISSEKTVNALHKALPCDRIAPLNVLIQINTSGEDAKSGIQPLASSSSSSLGQLSDLQRLAKHIVMSCPKLRLQGLMTIGALDLSLSANETEKNADFERLTETRDILERWLQAELVPEEADKNQVWRWGDESTGKLLLSMGMSSDFEAALKAGSDIVRVGTGIFGSRKTRDELKEPGAPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZE0</accession>
    <name>A0ABQ8UZE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_732804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="92" mass="10239" checksum="D4946D96FA3E707F" modified="2025-10-08" version="1" fragment="single">YIDWCKDNRVSRKHITDPSEMTLCNYAASFIGKEAGGTVRAKLAAVKNLVLHNGWRSGSRLCEVLNGVEKAAPASSLRPERDPVKDKWLDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZK2</accession>
    <name>A0ABQ8UZK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6697 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_984913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046520">
        <property type="entry name" value="DUF6697"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20411">
        <property type="entry name" value="DUF6697"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6697" evidence="2">
        <location>
            <begin position="213"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6697" evidence="2">
        <location>
            <begin position="295"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="437" mass="49624" checksum="220B5434CFF6A009" modified="2025-10-08" version="1">MLEAQNEGLEELSTSQTIGERISSIKNELDEDTTALDVDFEAKPASLIPKKSKKRMVEFETDNGIANNKVKMEFDGVLLPLPYRKRIKLESESALCVHRVNVPCIKEVLTAYSLHASNAPKTHARVLQSNSSDPGDTESESEESKETVEIKAEQNDDDVTFVGKSIDLEYLDIKPKIKVELELSRTLVQIRLDQFSCAPYPINLDRRISERRFSREFIHSVFGGSPYAANPPIGKEFLARHGRAHLMFWNNCKYQPNAKVGESGLFYESRPFSPKDDNEFIHHGFSCFAPNEWWEPTDDEIEEAQGLSDEYKHISAEEIKNAFDQGEQCLGILVLKCVGYDEDLQRELVQKFPSWVPKIKSGGKKAKKSAKRKKKNMKTRKVKAVREHDAIEEAGHVAGSDEAFNGTKAQQYKHWDQKSTRPYRIDQKTVAMALILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1B1</accession>
    <name>A0ABQ8V1B1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_860719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000150">
        <property type="protein sequence ID" value="KAJ4463926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="53"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="266" mass="29957" checksum="07F90AC7EE40BEA0" modified="2025-10-08" version="1">MSATNRVLAGPSGDCCFTGFRHEGTPIGNKITIANVPTYFVESSSSKGDSEAKRRILIFLADVYGPFYQNNMLVQDFLAQNGFTVLGIDYFMGDPVHLHDNEQGFDRSKWMEKSHDSAREVLPKWWEAVTAKYGTEAGYCVVGYCFGARYTMQLSEDDVIVAAALAHPAFLNEDHFRNIKKPLMLSCAETDHTFPLQSRRIAEDILVERKAQYFFQVFSGVAHGFASRSDPSSPDGRWGKEQSAHGIALWFHRFIDESFQSGRKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2T3</accession>
    <name>A0ABQ8V2T3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_142086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000152">
        <property type="protein sequence ID" value="KAJ4463815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045081417" description="Helicase C-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4463815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="149" mass="15475" checksum="B58146AD74E41518" modified="2025-10-08" version="1">MVLSALLAAFLGSAKRTISAFFPWFDVKDVGYVINYDFPNNCEDYIHRIGRTGRAGMKGTSYTYFTTDNAKQARELVAILKEAKATVPPQLEEMTMFGGGGGRSRFGGGGGGRGGRGGGGYRGGGGGGGGRWGGGGGGDSGYGGRNDRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V343</accession>
    <name>A0ABQ8V343_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_618392</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="354"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4470276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="647" mass="70202" checksum="8D6B05E2D50AD741" modified="2025-10-08" version="1">MSTIAASFVARAAAAGAASVLSSNSTSSGATSTNGTTTAAAAAAAGGAATGGGGAAAAGPSDFQIVWSIDIILLSLIALLFLLRLPRFLARMYRFSEWTSGLILRNRPYHMRTNGRRVQFSMSDNVSMDDLATDDSHATYQEKAFAQRISATGVQAQGSYPPHVSNCITFFRPLLKVMHTRINTGVSFSHVAMMLFWTGVIVFPAFYMTEAFTDPVRFGYITASQLPFVYAFGTKNNVLATFLGIGYEKINFMHRHAGRIVLVSVNVHGLGYIYKWCLASSFMEEIANPKCYWGLIGMICIDGLFLFSTEFVRKKAYNIFLATHISALSVLVIAMLNHYDGAIPWAYACAAFYLFDILLRITKTRVSTATLRAIPELGVTRVEIPNINSGWRAGQHVRLRVLSSGMGLIGWSEIHPFTIASVADGPEGMVLFCKKAGSWTNRLYDMANTTGSEDNVRKISVMVQGPYGGLGNCMVPSFSAATFVCGGSGITLATSTMQELIRKDLDGESRVKSIELIWTVQDASALVPMLPLFTSMIQQSVFTPIRISVFYTRAPIGKFPFADDFFRSTSLTLSPGRPKFHKQLEETITRTTALNSSVKGGNTCGLFVGVCGPVALADGVFAAASKIDPYRRDQIGGVEVHAETFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V415</accession>
    <name>A0ABQ8V415_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00298">
        <property type="entry name" value="ACD_sHsps_p23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="21911" checksum="97A93F0D95C1D045" modified="2025-10-08" version="1">MDDRAHFNSTIRFVRSMTSSLYTPRVDSYYNQKNQTLHYDIDVPGVQRSHLRAIFGYSAVLQNKNIAVWGASLAPYWPVQALSHSQEDSAELLPMSSPLMDQNSGEGEPDRPFSTVTNTSSSQMIPVVASVDRPMQRMMERNHGEFYRLLNVPAKTKVSDINVVLANGTLKIMIKCNKPLTANEVLATQEVIEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4S6</accession>
    <name>A0ABQ8V4S6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_559395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="185" mass="20558" checksum="36D78A702DC1E575" modified="2025-10-08" version="1">MSSVFVNTEATAPSALYVPVHKRTTSRGGASSRDSLSSRSTTPTSSEHDSSIGTLSIPIYSIQDLLLLSGSLLATLSPEQHDHLKDHAPEILPSRRQRKTIEHQRHYQGHAPGEVHPKEDTRQPLSSVRNTQPTTVQRRTLRQGRLPERRRYGKRITDELSWRASRTRTISATGFPLPLAPTAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5P2</accession>
    <name>A0ABQ8V5P2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphatidylinositol-glycan biosynthesis class S protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_731716</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019540">
        <property type="entry name" value="PtdIno-glycan_biosynth_class_S"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21072:SF13">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10510">
        <property type="entry name" value="PIG-S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4475835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="470" mass="52414" checksum="775D6C096E021A6F" modified="2025-10-08" version="1" fragment="single">LFFQSDPIRRYIIASYWVLVALALPLWWTTTSIERLPLPTSEVLAQAQKKLEIPLEICLDSAFSNEVSSMQDSLHHTSPYLDVQMNNGQDCSMCFCQFSGYAILPGERPSVEDRRLYYPPHAKNLAATLTSLFAPKIDHRAAQYSPRYRLSFTLLNEDGSAGQVITSWDIQQAFAQHIYPITSALGILHNFTVESQVQFHAPLAFEPRSISNGTAFGLTPEDLTVFINSAEWTLSSSSSNDPVLHFVLFVPSPARRPLIILNPDGTPSSSSAFLIPQWGGIVILNLPTPPPTTLELTFRDLRTPFSSFSRQLLTLLGFPRLPSSLSSSLSSSKTVSSWQIDTLLRQRTHENVMRSHDTLRSTVTLVSQIDGMPVDEQVQSQVQGSLKALHELFAHARNNLTLTEMLVHSARALTLSSKAFFHPGMLAMLYFPAEHKYAVYTPLFASAMIPLLAAGLREIAAWRKERREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5U3</accession>
    <name>A0ABQ8V5U3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_855874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045789132" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8242" checksum="D0D4CD97FFBAAF48" modified="2025-10-08" version="1">MAFSFAQLTSSMFLCTLDAAPISVGGNIRLCGKYWEMYHSEKTRRKKAFSLIIYFVESITKVPIHVRTIHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V692</accession>
    <name>A0ABQ8V692_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_911390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33518" checksum="3F3EA96DA5705D04" modified="2025-10-08" version="1">MSDPPPVLHLTFTMSAPVVVSEPPMFNPSSLPVAQLESLRFKANQIIESIKALQMNIDFHPTAISSWPDILSKYNLLLSQTHNFSSSLSTPLPSSSSTKSSPFEKIALHPRVAVTDIQLDTEIIPLLRNQQTTDVLNVENDIVRRLSEHMVTRGSVGVLSGVPIPPPPSHLHSSGTSTFGSTFSAAHLAHRKPEYEDVLQECELIRADHDRRADRAVRAVLLLREKFEWKTRVAVEVEEPEELSWDPAGRRGSTQMSVQVEEEEGAESEGDEGSSEEDEVEGHLVRDDTEPAVSTQISGDTDMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6W8</accession>
    <name>A0ABQ8V6W8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="33863" checksum="5E6BC32003E30E9C" modified="2025-10-08" version="1">MQQYLETVLVFDFMLKPNHHFSLHVVTDLETMGPGHAQSTPVFERINHSLQELNANQHLGEVEATMLTAYCRQANLELILDHNADVRQDIDEALNALKNIEREDHRGMFAGTDLLVWSSTEFKATPFWIQHSTPDRITDHLCGIYNVPRSHWSSTLTRQAHNLAGVAIGRVIYSHRVRQNSVVSCHDNTFLAGTIDKVFTHSHSHPVTQQWNTITYLEVLAMEAIDKWDDLYRQLHCGWLCLQMPITPRTLTIPLSSLVSHFVRTELSLAVKGNPVTHVYPVPKAFFDNNSALPTPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V745</accession>
    <name>A0ABQ8V745_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_515636</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="218"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4477935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="322" mass="36029" checksum="96F6C02F27B1DC23" modified="2025-10-08" version="1">MMTYPVLHPPIPYADHHFTFNPHLRLSNRYHDMDFFDQPVPAEKSSSGLFTTRETDGLIRFFDEFDQNKVDQTPWDVKPEPVEQDVAWYGMDNMQQHEHGMSSNTSSYPSSHLDVPPNVSVFRRRSFPLQSASSSRIGRLSSRTHNVSQGNASRSSPMNRTPSVQFAHLNLSDVPPSSLNYSRRASLPSGSLVNHTHHASHISELPLPRTKPLLSTPQKRLNHIMSEQKRRNAIRDGYAQLIALLAGPEGSHSVLVMPTRGRPKGSGAKGKQAKNGNEIEGAKGKSGVLYRAVEYCHWLEEGRDALKEEVERLEAAAGILSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V787</accession>
    <name>A0ABQ8V787_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_922985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF8">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE NADP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="2">
        <location>
            <begin position="26"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4477983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="355" mass="38798" checksum="9F8B778F2B44A393" modified="2025-10-08" version="1">MTEHLLANLGVPYSRPGTPGAHSNVQIGWIGLGQMGYYMARNLAKRVTPPGSQPLPLKVWNRTANKAEKLQQQLGKALITIAADIEEITTTCDVIITNLSNDEVVKEVYEQCARYLKLAPPVKNKIFVETSTILPRLSGELDYLISRLAHCHYLSCPVFGRPNVADKAQLLIVMAGEYRSKKEVAYLLVPAVGRKVIDLGENVEKAPTFKLLGNSMILGAVEVIAEAYTLGDKAGIEAGRIQDLIGEILPAPGLMGYADRMARDDYNGEDGFSLEGGIKDASHIRHLTAKYTAPMPMIDIAHQRLITARAIHTTQKEEGTQSHDVLDWTALIAGSRVAAGLDPFQSRKASDLFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7C7</accession>
    <name>A0ABQ8V7C7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TAF1 transcription initiation factor TFIID subunit TAF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_590551</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 1 histone acetyltransferase" evidence="5">
        <location>
            <begin position="312"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="788"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="947"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="874"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="788"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="951"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="990"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4472692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1026" mass="116770" checksum="872A56200FB88FA1" modified="2025-10-08" version="1">MAHNEENDAISALTGLSLGSILGDLNVTTDSLNNQLGISGIPALSSKQIYNENYDDEDAVGLDQGDDWEAQIDLEMAQEGDDAVKMEVNSPTLRQKQKRTRIVKRLIERPKTVYERFPAFEKDKVLDFSELFKGYTARKSRVGKRQFAVETTYPRKKEVPRGFLESVAGDTKRQVENKRVEAVISSGSIEADLRRALEERGTTNVQVSVPLHDRSFDLVLLSNWEDQIIYEPDPSPSAVPQSTDNSLTTSVNNVLESGVWTQSIIWTPDAPFRDFTQLEFNHEDDIVPEERSNEQIRPRKRFRTDAAPRDKFNLSNDQYYEVAKDGGRHRVRQTFGQLTVEHAYSAQKLQLPFYKTRLSKQEARSFHRPALQFPINIELHFTKVRTAKKKKDKAGRKLGKGGNVAEGLHTTGDLSLRDTSNFVLWEYSEEHPPIIPNFGMGSVLVNYYRKKDEKDDHVPKFDLGVPFVLEPQDESPFMKFGYVYPGQAMPALYNNLVRAPLFRHKPKHTDFLVVRSTVKGETKYFIREIKNLFVIGQTYPVTEVPGPHSRKITNTIKHRLQIIAYKLLRKSTGERLKISRLMKYFPDQNELQMRQRLKEFMEYHRRGPHQGFWRLKPNWPVPSDPEMLKMVTPEQVVLTESMQVGQRHLQDSGYSQTADNADGDEANLSVEQQLAPWITTKNFLFATQAKAMLRLHGEGDPTGRGEAFSFIRISMKEIFVKAGEDYEQKMAEAENRPKSAHRYNVAEQQQIYKSEIERIWKAQFDSLSRREEPLLTAEDLRRDALKTQQIEAQQQQANRDLTPLDSYSRGPSMDRGSVDPEATRRVLRIKRLVDGHWETEIVRDPAVIRAYIRNRQAIEEENTLTDSLAPTGDADKDKRAKKRIEEELARMKKNQERRLHRKNAKIVKEGGTPLQLNRPLKSETTRRCGHCGQMGHMKTNRKCPRWEEFNSGAAPTPGTSAASPSAATSPPATPSQSNIGFSRGPAFGHSTATSPLATSPPVTVYDEATPTSSAPKIKLSLGKKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7N2</accession>
    <name>A0ABQ8V7N2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp70 protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_774414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF32">
        <property type="entry name" value="HEAT SHOCK PROTEIN PDR13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4475411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="631" mass="66437" checksum="86C2BD873C18551F" modified="2025-10-08" version="1">MASNTQNGSADPSTEISNLPDVVGINFGNSFASIADGQAECIANEDGERQIACALSFFGEEMYIGSPAKAQLVKNSKNTIVGFRNLLGKKFSEIPQSQSTASAPIIQHPEIPDEPAYKVEILQPAPAPLPKSTTGTPAASSAPTPRSEPIPAERVLTVSEVTTIFLKSLLQSAEDFLGKRVQGAVITVPSVFTDAQKHALEKAAKDAGIIVYQLLEEPAAVAAVTTADAWSSMLPADRTQLIVDVGSSSLSLSLLALREGLAHIIASTSSTSTGGDAIDSKLITFFANEFTKKTKTPLTVCSETPPSTGDARAEAKLRLAIEHTKRTISASPNAATCSVESLKDGVDFTGNINRMRFDMLVRPIYDSVARAIVDLLAEAKVDPHQVDEIVYVGGTTCLPGLDEHIGFAGGFSEVINTPFSMGTVIGGGIGDPTTVLARGCAVQAALIASLSSEGEDEELRKAFEHGSDLVDVKTTSKTLGLVFPDNSGNETGGTWIPLVLAETTLPARRTATFDIGLSEESKRFAFELWEVSEGIRVEKISPAKVSPSDAEDEEEEEEEEIKHKTIIKETLLGAAEAEAVLGIKVKGPSKDAGKWTTTVEATLIVAASGSVDVSVKEIGKDGVVATVKVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7P0</accession>
    <name>A0ABQ8V7P0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_516884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18979" checksum="E96266ACF2EBBA88" modified="2025-10-08" version="1">MADAPISTYKTKKFWLYACAFALLFGLTGAELGLVSDLLHEGGNSETNYPSAEFKHDLGILLFTSIASLLYIIGHAFISMGLNIFVNFVLAVFWGTGAGVLFHVSPFESFTCDKPSSSFSPNWAVYSDRCARVVAMQGIAWALWGLSIILMFGMLLHLVEFKARKNVSMYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8X0</accession>
    <name>A0ABQ8V8X0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carbohydrate esterase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_798769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="30"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4480789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="304" mass="34834" checksum="09AED9E76123BC8C" modified="2025-10-08" version="1">MPAKRVLIGFGVDIDAVAGWLGSYGGEDSPSDISRGMFAGEVGVPRLLKLFRKYDMKTTFFIPGHSLETFPEQMAAARDAGHEIGLHGYSHENPVSMTQEQQRDVLDHTFKLLTDFNHGKPPIGSVAPWWEQSQESVNLLLEKGIQYDHSGMAHDCQAYYMRDEDTWTKIDFKGEAATWMKPLRRGKETGLVQIPVSWYLDDLPPMMFMKSSPNSHGWVNTRDVEQLWKDMFTYCYREEEEFIFPITIHPDVSGRPHVLLMLERFIEWVNTHDNVHWVTTAQMAKEFRAKVKPVEGAKMPRGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9H3</accession>
    <name>A0ABQ8V9H3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zona occludens toxin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_463993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="HELICASE MJ1565-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957:SF1">
        <property type="entry name" value="HELICASE MJ1565-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4482626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="52697" checksum="063424F054C8696E" modified="2025-10-08" version="1">MVVTISPPLTSSSCSTSSDKYDSNAEWELLDREPLKDSSLSSMEAHELKDAPIITRGAFLRCGSSTSTQYGVLGRVVACHFKKDVHTFSDSRIYLNTNAPMSTLVCGVQGSGKSHTVSVILENMFISSSSLGTLSKPLSGLVLHFGEGGAGSGPCEAAWVGVSNHPSIKAPQVKVYVSKSSLNTMKGIYAPLTQRGNVTVEALSFDESELDAQAFLSLMAVGSSDNAPLYIQIILSILRELGESFSYQAFMTALELKKKTFNPAQLSGLEQRLALLTSFMAGKKTKKLKALTERKRRFAPGQLTIVDLSDPFIDPASACGLFEVLTRLFVRAEVNTGKVLVIDEAHKYLSSNNHPSGFTKALLSLTRQQRHLAMRVIISTQEPTVVNPVLLDLCTVTILHRFSSPAWWQHLEKHVPADFSDNDAFDKVVRLQTGEAIVLAPSGLATFPSPANGEHNVGQIGRRYLILKTRKRVTIDGGASIRVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9K1</accession>
    <name>A0ABQ8V9K1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_841967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045789135" evidence="1">
        <location>
            <begin position="27"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="226" mass="25049" checksum="578AAAC1F0DA5D36" modified="2025-10-08" version="1">MIFPTFAHPVLLYLCFFFLGLSTLNAIPLIQDSNGLTSQGSQSKTAVAYPQKPLNDLIPLYFFTCEAAAVLVANGKGLKEITPYGTAFRFALPIQKPSVDASTSRKVSRYRYLLYDPNHGIPSLARPDSCLQNYAVVKFNLAHPDADIEDLAGIPELSHKVQAHKDKPSHLENRDVIMLPYEKDKNIIVAALLTDIVASPPTLMYASHRTGRTPEAAWLKMSLHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9U2</accession>
    <name>A0ABQ8V9U2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_770364</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025836">
        <property type="entry name" value="Zn_knuckle_CX2CX4HX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051714">
        <property type="entry name" value="Znf_CCHC_NABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23002">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14392">
        <property type="entry name" value="zf-CCHC_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4482737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="172" mass="18914" checksum="FF710B7E16242DD8" modified="2025-10-08" version="1">MAYQFSRKGCFKCGNLGHIAENCSSEQRLCYNCRQPGHESSACPSPRTASAKQCYNCGGVGHIVAECPSLRVQQGHNQKCYNCGRFGHIARVCPNGAVKSEGAFTSRPPHGRTLNTSTLPPIQCFKCGLLNHRAKSVLIKLLSQFLFTHPVYTGTVWLLGLALVMFRLVLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9U7</accession>
    <name>A0ABQ8V9U7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II assembly factor Rtp1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_770640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tango6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057407">
        <property type="entry name" value="HEAT_TANGO6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019451">
        <property type="entry name" value="Rtp1_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039600">
        <property type="entry name" value="TANGO6/Rtp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20959">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20959:SF1">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23565">
        <property type="entry name" value="ARM_TANGO6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10363">
        <property type="entry name" value="RTP1_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TANGO6 HEAT repeat" evidence="4">
        <location>
            <begin position="253"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase II assembly factor Rtp1 C-terminal" evidence="3">
        <location>
            <begin position="724"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="608"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="917"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="613"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="922"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4482747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1019" mass="112074" checksum="CC601B18472AFCE3" modified="2025-10-08" version="1">MSVQSELASALHAGSCLIDTLSTPQTQLKSALIQRLQNYYSCLGSSSTLNDSATLENVQIRTADEALVVVEKVQRLLSTNAPDAGAPLLGTRDLNQLRVLLSITFRWGVDPLLSHVISSWPSTSSSTVSGAKIIDLTSAPEDYHHLADLVTRQLTLVFPLGIHGNMSSTLIAEVILQRHLPDILKPAISLGWLPKSLAVDTMTPLDDIRPLIMRLIAMLPPVESIVALGSVISSTNLVPHIRRTCGYLMSKQLLRPEGVKGLCAAVFGDSEDADDIRLDKLQHISRVLITVPAGMKPKDYFSILLPRLIDLLQENRNPAYRRAAAFALSQMLAVKNGTAAQIIRLQFHDLFLYTYPDTEETDVTIVLGNLTTLLTNSDPSPELISTLLSPIVRPLYGLLFHLDSIRTSDPELKEMVRGLLMTWSRITSSSEAIDILWTIFDDEGGQWHTDLEGGVRRGPSVPALASTKLSLFTPETLKKADEAGELDPTANILDLYPEPRHLAVFLQSMNRDDILSQFLVKLLEGYRDNKNSEDGNPVRTLLYLQLIMQLQITISDSSKSAGLFSKPSQILTFIKQALEAAVSARPKPKPNNQKNKVSLAGEFQISDLRLSPQDEEDPEVSDGDSDDDLSDSEAFTADNEMEETSITLLLSVLEANENLSARTEPILNDIFELLEPRVNHSPSAVRSVAREARMVMTARLALGDDNVPRNNYVDTQADSPLEIYQKALKFLQDPILPVRAHGLLLLRQLASASTDSAKMDPALVPAVLEIFVQAIQDDDSYIFLNGVQGLAALVDNYDRSILKRLVYDYTKHLDGLEAGNMTQQDVDTRIRLGEALSMVIRRCGETLGAAGNVIIPPLLRVVRSRTAPTTLRTSSLSLLADCQNTYALAVLPYLLDLAEGMIDLLQVETTSTTDNTIITNSEGRKSTMDDHPTSTNTKFPPLRRAALHFLTLLIRGTTKEIHESSASVGDNARLSAGLTKRMRITLGYISNTDDDMLVRVMAREALEDLAQLELAKLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA17</accession>
    <name>A0ABQ8VA17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_849067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="57" mass="6503" checksum="C8DC66740173C8AF" modified="2025-10-08" version="1">MVRDSIPLSLYHTGELSRTLANILQVSEYICPNVTFKICGARIVYGLLECRRFLDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA35</accession>
    <name>A0ABQ8VA35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_775654</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4473542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="101" mass="11456" checksum="F449DB32A3A43C57" modified="2025-10-08" version="1" fragment="single">VNPVNPKPFIQELTGKSIRVLLKWGLEYKGFLVSTDGYMNLQACFPSMVNTEEFQDGKSTGTLGEVLVRCNNVLYIRFVLVVIYLINNLIIPLIVERILHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAH0</accession>
    <name>A0ABQ8VAH0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GMC oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_769554</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF218">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045757021" description="GMC oxidoreductase" evidence="7">
        <location>
            <begin position="24"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="57"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="9">
        <location>
            <begin position="492"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="644"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4484433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="72815" checksum="755806BEEA465EE1" modified="2025-10-08" version="1">MWSIPKTTILALSSTYLFSTCFASAITDPLEAHRRRDAHNLRARNIVSDSSAIQSSYDFIIVGGGLAGLVLASRLSEDSNHTVLVLEAGESGDANITQINTPADTYYSSLVGSEYDYAYQTAEQTGCSNRNVSWPRGKVLGGSSAINGMYLVRPNEPEINAIHAINPNDTDEFWAWDSYNAAMKKSETFGAPSSDIAAEAGIQYNAASHGSSGPIHWSYPGETFNIVGNWTPTLATLGIPSNPDSASGDNSGAYITTSSINPSNWTRSYSRSGYIDPLPPRSNLDILPSATVTNIVWGSGTSGNLTATGVQWASSSTAAKQTVNANKEVILAAGTIGSAQVLQLSGVGPSKYLQAAGVDVQLDLPGVGQRLQDHLSGSLIYSTTAETAGDLHADGVATAEFLSYINSATAYVNLTTLLGSDSASALISSAQAEVDSSASSLLPLSDSTVAAGYKAIYDTITNQFYSSNSGQIELLLSITSTSVLIQAAIQHPLSVGELYITSDSVFNYPFINPNYLVHDADLTILREGFKMARLVSQASPLSTYLTGETTPGSSVSTDAEWDTWIQGAVGTEYHPTGTCAMLPLELGGVVSPSLLVYGTSNVRVADASVYPFELSSHLGAPTYGLAEQASTIIRDYWNGVSTNPNTTTTSTSSSSSSTSTGSTDSKSNNAVSSAYGFGGIVCAAIACLVGSMMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAP5</accession>
    <name>A0ABQ8VAP5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_982393</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="1"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="827"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="827"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="952"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="861"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4484505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2147" mass="237558" checksum="219CA1DDAA6CBA8B" modified="2025-10-08" version="1">MKPFLQIASKVKGRVITDMGSFLKDIHMFDPMEFGISARDAKAMSPATRKLLELSFLALSDSEIDYRGRNIGCYMTAEMYSTANPFDQESQGSFAGYPYMIANKVSYHLDLTGPSIPVQTACSSSAVATHLAVQAVRNGDCEAALVGGCQLNLREEDWIQYSDGHVLSPNGKCKPLDASADGFAKGEGAIVVVLKLLEDALRDGDHVYALILGTGVSSTGSQAPVSAPVASAQAIAMQKAFKGTGKTPREVSFVELHATGTAVGDPIEANWVGEHFERDGPLLIGSVKGNFGHLECAAFLASLVKVCLMFEKRIIFPTANLRTQNSSIMWDKYHLNAPVTAIPLPETSGQTLVSINSSGIGGVNAHVLLQSRTSNSDHNLRKFPTNHKILFVAGGLLPRSATATSELLAKLLNENPEKVLNLSTAFGRRSRQMTWRSFGILNSGKALQFTHPVLVPRHPAPLVFVFSGQGSQHIEMGKELFECFEVFRGSIMESDRIYQNSTGTSLLQQTGLFSGVVSNSLIDQTWPIAVTLPALCMFQVAIIDLFKSLGICPDLIIGHSAGETAAMYACGSADHTMAIELAIARSRAMALIEGTGVGMVALGCSAETAEGIIHQTIQVSSQQVVLNIACFNSTSDVVISGHISGVELVMEHAKGLGIFAHRIATNVPMHSQLVLKCQREYLAEVKEVFSQHSICTPQIKTYSTVTGKLVEAYSPLYFWQNAVQPVLFSQAITAVLSEDSSSTFVEIGPHPVLLRYMKCLGATPSSLIPTSHRSGSEHHFFLEALGKLMIQGHNSLDFHKLNGTLKSSKLDIPLPPYPFSPKVVQYHTGSMGYSNANNHKLLDIREGMVSSHFTEPYFVDHCIIGEPIMPAAGFIEMALETGVNYLWDIEFESVFVLKGRYKLKLEEEGDYWHIISESGDGAIPRKHAKGHKLADPQLKMMHMDLSSLHTCEVVMYGNEFYETIHYFAQYGPYYQRLISLSRGASEWIAEIRGLFKHEVNGFVLHPALFDACIHATVHPYVTRNADRNSYFLPSKAACVLFNRSNSQAQTDPSVFSVIKLENWEPDACTFNVSIIDSSGKRICQIMGLEVLRHIIEPVQPPSHCYEIAYQHLAYLSDLEPDLCVEPSALTSLAATNFVPGTELTIYQEVLKFQTMGHRHIYLQATDGINSAFAEGFTRSLNKEMFGSQIHLVSFDSHINPDSYLRQTFALAQSHSLREELEVKVTLSGEIYSPRIQPVSHGNNNSFTLKDQQYTRPWKAIGSASSIINQLEEVYLPSLLPDHVLIEVEELSMTYLDIRIFKGIICDAGSTNWPIGSRVLGVKDSTISSHCHVHSNDIMNWSGITNINYAVPLLILHLGLGLNYLTQPLLRKHNHISILDITGSFLLQALKDIMETYNINVSLISSDISAQVILSLQHSDTILCGLKSPTEIYKLQCMNIARTPLFIWNDPGKLAEHHISRQEMLKVTMEFMGALESFGRLQIPSALQLADVRKAAHVQQHMFSGKKTYLVIGGIGSLGLQIAFWMFKNGARYITLTSRSGEASLFNSSNHSAIRLLSYLRTLENFHLNLQSCDAASLVDMQALIGGIEDLGGCILSAVVLSDAPLSSHGPDSYYKVFPSKVDVFKVLTEVIQIERLEFLVLLSSAAIFGSAAQSNYASANTAVDHMAKQYRNAFSLIVPAIIDSNAVTHSENLAPDPSLSHWLPWAVSCQDLCCYLEDGIRQLKDRNFWMYIPNLDWEKVQKYFGPSPLYDHLVASSQSTLEVQSYTNVDLTALQKVICDILEISPEDFSSEIPLIAYGMDSLSASRLSIALKPMVTLNQLQLLGNITYKDIQQYIAREGTKLNVEEDQPDVQYFDWKDLNKKGETVIKLIDTSVSEKPPLICIHGASGSILAFKPLQESFKSALYAIQVTPETPLDSLESMAMFYWQKIKETVPRGPYRLAGFSGTCLIAFELARVIHAEGQHVSQFAIIDYFPTLFLPPHFTLDDESVSQCKATRNVVFNALQSMLKLYENSTNTSRREIAPKFLIAFQESFNGAQVAGMSQDKTMAQSFYHFHAYVDMVVKQLVSLSSMVPLEDGMKKWLLDAIQPLRCPVDIYIAEKGVTTAYWYNWKEDCMNYLPNVKITKCSGDHFTVLEDAKCVRGLEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAR9</accession>
    <name>A0ABQ8VAR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AIG1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_868531</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006703">
        <property type="entry name" value="G_AIG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046">
        <property type="entry name" value="G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046:SF11">
        <property type="entry name" value="IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING PROTEIN 10-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04548">
        <property type="entry name" value="AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIG1-type G" evidence="4">
        <location>
            <begin position="44"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="504"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="532" mass="59689" checksum="769C1E0284A09EA6" modified="2025-10-08" version="1">MSQPGLSNSTNPPIVPIASAGTNVSGDKPARIMTIQSWAKRVMNIVLIGETGVGKTAMLNLLANVCAGVPMEEFEEKNELNNEEGGSTAGSQTNKPRFYSITSANGHKVNILDTPGLADTRGIDKDKEHQAAIAEAIKTNFDVIDAVIILANGTLPRLGAATEYTLTTISGMFPNSIVDNIAFVLTMVSNPSSNNFTRTSLPKQLQNSRIWPVDNPFAQWLKYQKELLKDPPTSEDDLQEMLGSARRGYNKTLKMLSELFQYLDKCRVQPTHSIFDLYIMSTDIEVRISNVIAGMTQTEDKRMKLKKLQEDYQTLGHTMTREKYERIITSPVYEHEDTGSEHNTLCVAGNCYKNCHPGCSVGFTMDRETLARMCASFDETPGVALLKRRCKDCGHLAEDHQHYRSKWVKKVKTDKVIDQEVLLRYNAAKNESDRVTILMTESQKEIKQFEENIVGFEKELTDLCEKYNKLSLSGSFIGYISSAISLLTIRQVTLVKDGSDPEAIDRMAKRIERLEKKRKVLEEAEKQRGRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAU5</accession>
    <name>A0ABQ8VAU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_921664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="544" mass="62003" checksum="EC9EB6FDA0255302" modified="2025-10-08" version="1">MAMLSGFVGHQGRVHCRFYCPLIGRHKPGASQYYPVRLKPDNYSVSGCDHGDVDLDALLKSFTSLEASTRYQANLAQVVLSSGHSQYEKNRLATGIVKPSIFSGLQKQYTTAIPGLFAGDIMHLFTLNAPDLFIPLWRGKFECDKTDDRVLWDWAVLNGDLWIEHGKCVAACTPYIPGSFDRPPRNPAEKINSGYKAWEFLLYFYGLGPCLFFGLLPDKYWENYCVYVHAVQILLQESCLPSEVLEAHKLLLKFSDDFEAFYVQRKTNRLHFIRPSIHSPSHIPFETIRAGPGAIYSQWTMERTIGNLGEEIKQHSNPYANISQRGVRRCQVNALIAIIPDLVPDSDAPPQGSRQLESGYMMLTATDTAARMVTDIEARALRMFCFELGDPKPNTWVPKVVRWARVKLPNGQIARSRWKEDTIALSDIRTSRNVKIVLDNKEYIVEVHFYILLKISETVHPVAIGSFYGPPHEELLRRSHNTYYTVQHRRDEDVRAFPITSIDSTVMMAPDPRYISLFKDREPDGTHLNRWFKMQKPGLKVSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB43</accession>
    <name>A0ABQ8VB43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4485090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="278" mass="30926" checksum="7B258B93123ADB2C" modified="2025-10-08" version="1">MLSNILSSPSNYEPSESSGSPLKLIKRKRTWYSSLETSNLTSAQEDEESSNEEGMKLRPPSSSGRKQISLLYNLGIEDSQVETQHWTEGMRCLNEDKITFTKSRRPSPSEDVHFSQRPHGWFGSDELNPVEDDAAAAVGKDAEVKIKDGPQDEFKHARILAAENSQLVIGVTTLKCQNEKLQAHVDRTLHELKDTLARNTQLTCLLDQSRTHSTSLSYKINSLLEKALEKQAKVNALTGIIARTGDIFVEFASGTFGGEKLHMQMNSVLLNHLEGSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB93</accession>
    <name>A0ABQ8VB93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_982199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="464"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="552"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4485132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="726" mass="82095" checksum="08F0DB0F99A46B37" modified="2025-10-08" version="1">MSPNVKCWSFNAETGHPIGPGCTRESCLFIHPQDKRWASAKSSNQSSYRSKMQRMEKQIDRERDRDRDYAGRDRDDRDRERDRKRERDRDKERRYSRTRDRTPEYSKSSRKDGGFDRDDHWSLRRRSESQLSASSIGHGWGFEDKAAHTSGGSGSSKVNDRGWSTGSGTGQDSNEKTGGISPWGSGNAGTWGTENNQTAWGAGKPSGWDSVEKAADTGAWRPLEASFSTFQKQKAKENTNAPPPTTSPPTWNNTSTSKSRKASVPPSPSSASPFPLSMSTMPDIAAGEPVYTNSTPKAPRAFTQRTAGPSYRKDSNSRRSSPNFRYASPTATEHTSISVPSSRKALKSRRVRKLLGLFDHAVKKEVERKTVAKKYERWKKIQESPQYGRVRLNGQKKLDNVRGQLKKRRDKLSERVKYEIKAIVNMIQPSASSPSQSSNIDIDELKNRVRARLDELSAYILDLKHILEEQKKTEEAAKEAAKAREAKEREATAAALSAAASSRAQEITLENLKTRIAELEVRSFEILDVQEEDRARFLSAEFIEEALEVQEEDSVYDELEDLEERIEKTGKQVSNQGMEISKLSSPERKEKKDALQKQLHRIARLKKELEAKVAVLDQDAIERREKIDDLSNQIQNLHNRRKPSHSYSQHLLPFVERLIIRIVEQELKPIIVELRTTTKAQVRVRQHIISGAIEKAVEPIVQMTTDIVQRSNALAGVRDIMSSAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBF1</accession>
    <name>A0ABQ8VBF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_843473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4479454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11709" checksum="5030F3F030D4576D" modified="2025-10-08" version="1">MVIFLALRIILVYYVFIRCFATDKDVFGRLVGVIKLKIRKSDIADVSPNCVKMNLFELRVKSLLLGRVKTERDQRVQRGRWYRIKARQVRALGKQQQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBU3</accession>
    <name>A0ABQ8VBU3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_868221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="233"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="44297" checksum="5A577C495B3A60F8" modified="2025-10-08" version="1">MAQSVTTVSPEVTIDNTLGALFVGFAMACCIYGILLSQIYTYLGNYPLDRPVYKFIVLLILTLETVDQALIGQIYYHYGISNFSNPLTLIEGAQTWFVLEYQYMNNIKTSDSENFRSFILQQTLGSVVGTMVKISFALRVWRFSQRNFWITGLIVSVDDEQEGMSILNYILDGSCYRWLVLGNCLQCKIVSLDRIRILHSAQKFVSFARFMLPDVFSVVRLRVLGTISLGVGVLTDIVTALALCYFLNKLRTGYRQSDSLVSSLIKYAINTGALTSVISVTTVVLYNLMPDNLIFIAVFFILSKLYAISFMATLNTRRVVRGRGTDKQNTTTNRTNMFHLGTRVPSMGPTDMDGWETAYTTTSATKQEIDQHRSIPLNTFAPPNTTFGKYSTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCG0</accession>
    <name>A0ABQ8VCG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_841769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="494" mass="50697" checksum="849E345E6D71DDB1" modified="2025-10-08" version="1">MSAPIISPEALPSTPAHEWANETLNSVPSDSTVSTSTTSAAVPSSTATTPGLDFPGAYPKTPSTQLPVSVNEIADRARVAASTAAANVGDAVNTLPAAETISGSVAGGFDGVKEVLFNATVTASQYLPSNVVEYFPGGSLIVAASTAERDAQGIPLPSTEHSVDPIPSSQGVGSLPGPSSEEGVAKLPLERDLSSNHSDELKIEQGIESRNSLANASMVAQDGSSAPTPTTPRTPVQTPVQHGNISSHFTENLNQQVPPSSSPTHPFKGKSPTKPAPINLTPRTHPLAASGVGAHWHGVPLDEEYQKNVVDKSLDDTQTSSTAIDADIPVPNVPPIATIPPIPNVSTPPTKPVDSMSSISPHSPQNDSTIANVGHDKLTSGTPEIPSPHHDGATPSAAIQDHANHAKQISEPPSAFSTSTPSSTGSSVNKGAAHGKESSNGSESVNSTPSSTPLKKKTTLLSKIKGEAKIISGKLGGKEEKVEAGRRLIRGEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD10</accession>
    <name>A0ABQ8VD10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_836591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="29234" checksum="E7EA30EA0ADEFF49" modified="2025-10-08" version="1">MEVQGQVGDHTLAVGFPTGSAFLLGRQLPKSRSEAHLKRSNFHSFSPSSSHFPNTALVVVFRSDIHTILRKILLTLVETSMQSRLSGMNLYLKICFITILSVACVVVLPVSGSELVHRADQAGPANQQHDLGDRHIPWKIMITFFFPLEMTPEASSVLAHREGIAASIHNEIAANTDIATRYRISTLKQIPSLLPPGISYEGDVSLRLTWNGPNHVFESRGKITANGGISEVNTIDVEISFPAGDAGIGIRMPGVPEEIAFTVPVYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDS9</accession>
    <name>A0ABQ8VDS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_766740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08254">
        <property type="entry name" value="hydroxyacyl_CoA_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="9"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="37136" checksum="BB04B5FF0E5BEF57" modified="2025-10-08" version="1">MTAYRWFPGAQTLTKAEVAVPEPAADEVLVKILAAGMCHSDMLYYDTSFQHTKTKPFIMGHEGAGEIIALGESVPSTYPDFHLNQYVVIHARNPCLLSTCPVCSIDADNLCARYFPCGLGIDGSYAPYMVVHARAIVPVNATKDEIPPPLAAVSTDAVLTSYHAMKDLRAGETVLVMGIGGLGINAVQIAKNVKGAQIVIAADLRDEMLQEALEVGADYAVKPEDLGSLLYNHGLNVDTAYDFVGVGSTFKSVLEHIRPRGTVIIVGLGATCVELPLVPVTRKEVTVKSSLWGTKKELEEVLVILKDKKIRPLIETRHFVHALEAFEDLKNSRLKGRVVMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDY4</accession>
    <name>A0ABQ8VDY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_383912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045599347" evidence="1">
        <location>
            <begin position="21"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="227" mass="24881" checksum="0058F688AB20633B" modified="2025-10-08" version="1">MGFPCFSNLLARFWLYLAISFRFFPRSFENILIMNVLNSHSFSYSVDAGTSSYTYLENGPATNCDATNSKTTSSSMDHCTIVEQQSYTEFCLKLGSTMPKQEDASGNTLESPLRRRSYVCNWRQNITPLKIGPPPSPLGISDFPTSPVAIVSAEQLRVTSLPPYDPRTASVLAGSSTSELSEQSIVDEPTNFHDLYDAELEQIIDGIETSSASSSSLSATVYIPPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFT9</accession>
    <name>A0ABQ8VFT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation initiation factor eIF 4e-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_339237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0696 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015034">
        <property type="entry name" value="Bles03"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977:SF1">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08939">
        <property type="entry name" value="Bles03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="261" mass="29977" checksum="97482C00AF6F68FA" modified="2025-10-08" version="1">MEETRSSDFQFNESQTSSFSSSTPYVKYLPTIFSPSSHVPYITTTNNWITAYFNEYTASLSNVERFTRYWRPSFHLNYNQSQSRSGPDNSVLPTTKWIAVNRGLSSLESTSLPRIPELKAAFDALASVHHTNGHSTLTVSKLDNLAIKYNILSGKWLVFTSVNTVDKLWQDVVQMVCMYRQRGFAKVSVNQEEEVGKMNNSRVICVYVEDFTDLEEVRSLRDDLRTVVGVERKIPFKMDAYSHMGIYKGNKWGISPARWFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG02</accession>
    <name>A0ABQ8VG02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4487007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4487007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="622" mass="67645" checksum="2EC5713ADEEE89C6" modified="2025-10-08" version="1">MFFIQRRGLQMRLPKFSPKLLIQFWQQLVVGARLSGAYSCTALLIMADLSLSVTQVQALHTLLLLQGSNLPDDLKSLPASLQAQLALNSSASSFPTPSPSPEKLPRTGSISLARARLRPPWLFSQPRATCEVGTQVEDPALALESFSRPSSPASSAGYGAGSEVEEDLGGNFAHNRAHNFAHDRAHNFTHDRAHDCALDFPHDSAPNPAPDSTHDFAPSRAHNSTPNRTHNFTPDSAPNPIHDPAQASNPDSIYDDAHGTPSHNPGCGSIREAAHCSAQDPGRNSAHSSSQEAAHDCGGHVSTPSCSHNSDCESSYELAHHPRNSSQASVYSSTHARYLCDSQDTAQDPTLKINEAFSDDQGEAEEGPLLANTIYPAPSEADNESLLDHDTLLADSHRQNADDPNPLLDELLEELLNSNNHYQEKMILCSDLDAAILSLLEDACSRPLVNSPTRQTGSYSLGEEVPVEVVRPRVAQANPFDPRPDCNRNGASASRKRPRVNHLLNLDFGEEEEQRGGEEENMGPQFLYEASDRPHTPPKEVTDASLGLMLRLTGGAGWGTNVWAEDICRIVACVDWEEASGALSSYSLLHLAQRCSRAEKIDTGATFIRMMYELFLAAKVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG44</accession>
    <name>A0ABQ8VG44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_868055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4487452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58290" checksum="7CCAFD19CB298004" modified="2025-10-08" version="1">MAVLCDQFAITLTLAKTMTVAWQSIFLPKPREDRLPETAAAHTQLNPLDEALLDMTSYDELDMPKRLLTEDLSPQTFHQGKPYVESNTGFDAVFSLPLLWSSLSIESWHLYGRPALADLVVTYISRSGNVPLKIHLKSEEDIPEVELQVFDALLEHVSRWQEATLYISLPWLLHTKTKLGSRLFPGSTCFLELEHLVLNVQRNSQSNQDLTRYFPNQIILSSPKLNVFYGIGYDSSFNPRGFGRTYNHSSVTKLVLHRFTGRSLGHFLSCFPMLETCSIGGFQLSEDASNDINFEDDLPIYTSKITHLCHAAPWDTFQGGAWRFLRIPDLTSLELRYNGYSLTQVSSLLSSSGSILSEAKLYNFPIDEIINFLSSHPSISHLCIHVDGELGLLDQLTTGLTFVTDRWPVVPNLLSFELSWSDRGYKRLRDLNTMALQTVLRNAICGMVESRLSLSGNRTQGLQRLALRIRDGDFLEFELLYEAIRNKLSCMEGFDFETLTAQFSCVKTHSASPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHV3</accession>
    <name>A0ABQ8VHV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">T-cell immunomodulatory protein TIP C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_830744</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057089">
        <property type="entry name" value="C2_TIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024881">
        <property type="entry name" value="Tip"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412:SF0">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23122">
        <property type="entry name" value="C2_ITFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046815865" description="T-cell immunomodulatory protein TIP C2 domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="619"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="T-cell immunomodulatory protein TIP C2" evidence="10">
        <location>
            <begin position="516"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4493343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="665" mass="73256" checksum="44BE947BA796D044" modified="2025-10-08" version="1">MLCLRCKFTLYFWLLALPTTFAIWPFETKRFSGNSLLNAGSLGLNDPGRVVAFGDFNGDQFLDVLMLGNDRRTLSVYLWNHEEYTFQKSSSMKHPNDIYNVVPGDFTHSGKLDLLVMSGSWASGPLDLSVYPARADGGFDVKNPFYVESSSQSQPIPLDLNGDMKIDLLGMTASSQHNSETFQTWKNVWNASQPHSPLFEVADSPFHGSQCIISNPHSNAVVDLDGDCLADVFLVCDNGNGMKYFQIWVNNKDDGFALAHQGSLPSGVQSITFADIDRDGTIDMVFTTCSSVSSSSGVGSNCYINIAFNQQLPLCATAQPAFTKGIRTCRSPDNLCVADPNFKFEFSGDPDVFVRFQVSALFPDVSTPSLLVQDTTSSPSIPVAIKLGDANLDGFPDMLLVVSTSQGRTPKMVYSVPCARGIIGCDANGKRGWQVVKKGVESLEEVKDARGISFVDMDEDGTLDLMVHRTGDSGQGNILFVQNNFYYDAFFLKAIVLNGACNNGWCYTKDGQKYHPFGVSYSGASYKYTVLDLSGRRSAAQVGQLPQTSYHALQSPYSFFGLGRTNNYIENLFVGSTIHLENHYINMEGVIPNSKVVILPSATEGEAWKRELFLRPGDWIPWVTVTVVAGTALLAIVVLVLHLNEKREDELERRRVSHHINFDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ19</accession>
    <name>A0ABQ8VJ19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PPP4R2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_895227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="30806" checksum="4F94491005AA5862" modified="2025-10-08" version="1">MHMSSDAVKWDLLKDIIKHKTEQNISMFLSSTASPPPAPSFNAVHMQNGGLRLPPFPPRQQNNINMIEAPQNYLNEEQTRALKESIFAQLDTFDSDPPFTIQRVCELCVEPKKQYKSIGKYLRAVEKSTLVTSTWAEFPPLTEQEKDANLRSKISTGSQPLSIPNTPLFSPIPFLHNDARRSKSRSPPPSPLALSSAGPVSGGHPETLSLEPAPLGLVDELDDPRPGHMSDHPTALSAVTTVDDGKEGTPIVQSLESRFVKAEDEDSTMAVDENKENQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ71</accession>
    <name>A0ABQ8VJ71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="19673" checksum="5147F3D3A676475A" modified="2025-10-08" version="1">MQKDLDTKERNTGRRESRLGMSIILTFSKGSSSHKAAFQQQNQPKVNILASEECAQCHDGSQTHPYIEADAQAPAGATIPVASLVPFTELPSSFDYSGFLSSMNPPSGPMTDELNTEANSLTPAHPFHNPDITRSSTSLPAANSQEDPCGVAVRDSSEDSAIFSPAPLPSRRLSALRLTFILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJF3</accession>
    <name>A0ABQ8VJF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hsp90 protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_895233</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="214"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="700" mass="79328" checksum="DB09A1BC0776341A" modified="2025-10-08" version="1">MATESFGFQAEISQLLDLIINTFYSNKEIFLRELISNASDALDKIRYASLTDPSVLDTGKDLVIRIIPDKEGKILSIRDTGIGMTKADMVNNLGTIAKSGTKGFMEALSSGADISMIGQFGVGFYSAYLVAERVQVISKHNDDEQYIWESAAGGTFTITQDTVNPPLGRGSEIRLHLKEDQLEYLEEKRIKDIVKKHSEFISYPIQLAVTKEVEKEVSDDEAEEEGDAENKPKIEEVDDEEKPKDKKTKKIKEVETTNEELNKTKPIWTRNPSDITPDEYSAFYKSLTNDWEDHLSVKHFSVEGQLEFKAILFVPKRAPFDLFESKKKRNNIKLYVRRVFIMDDCEDIIPEYLNFVKGIVDSEDLPLNISRETLQQNKILKVIRKNIVKKCMDMFSEIAEDKDNFNKFYEAFGKNLKLGIHEDAQNRSKLAEFLRFFSTKSTDEQTSLKDYITRMPEVQKSIYYLTGESLAATRDSPFLEVLKKKGFEVLLLVDPIDEYAITQLKEFDDKKLVCVSKEGLELEETEEEKKAREAETAAFSELCTVVKDALGDKVEKVVISNRITDSPCVLVTGQFGWSSNMERIMKAQALRDSSMSSYMASKKTLELNPSNPIIKELKRKVSEDKADKSVRDLTYLLFETALLTSGFALDEPTSFAKRIHRMISLGLDVDEEEEVAAEASTTDAPPPLEATASSAMEEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJW8</accession>
    <name>A0ABQ8VJW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_316612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="451" mass="51054" checksum="B5F28FBDCF80108E" modified="2025-10-08" version="1">MIQLIMNPSTVQNSNGSPIRPSEQLDPAQILLLHWGDFMCWCWETWNDYRVANTECVTQLTATWLYHLQLGVDSAPYQDIHNPHILLDKNPSAANYAFLQVLHRSTTSLLAARQNAILQESFYVVLFNACRAIDHLLRNQLVCGAKLTGIEITAKCLLGVFVLLRSETGDNGRLQLKSTILESLTMVNEEAFAQAINDTCEDKEIHFKERIDELILQSRRGLIRSTESEQNLSNAQADEVRLVLYLLLRIWHSAEGRKHVQRQPILNLLASLTNRLLKDQIASPLAYNRLREAIVTGFCILDTDPAGTPIKSPKQEDVWRFALNAGCSNLVVTSSFSHHVMAVARLPDPLTCAEAWNHLRDTMTLIFRRQFLEDEQAVALIVSLGVCGALLRLLYSDVSTERFVLSSPWTMSFCVELKKILQGEMEESENDYFHLLKRQLISIGPVLLDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK46</accession>
    <name>A0ABQ8VK46_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_824740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11692" checksum="11CF3F948721C8AE" modified="2025-10-08" version="1" fragment="single">MWANTSPLASYVRVITAPSLSGSIALASALAELRCGTDSIPGLSPSFPLLYFSVCLLRTVVRLFVICWTKHVLSRPAAVQALDGSLEFKYCGGNRALLSHCLSCFLVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKX8</accession>
    <name>A0ABQ8VKX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="606" mass="66415" checksum="782F73A8349D909D" modified="2025-10-08" version="1">MSSAEPADDYSNSTFHYTSTPAPPPPTTTTNRKPNQHQQSSSTSSRPGSRSRTHSQPSNVNNANRALSSSRPTSPPNQSAKTNQSRIPLPQRTRSRTGSLSSQSHSQHRTKTPTPGDVAPVAAAAAADLWVVHERPSHSRLVNEPAPFPPPNSSVSSIDVLPEPRPSNDSEERPFEHWYRGEVSRNGGVGEYRVAKRQEMLEIANYGHNIRPKKQNAITDAIDSEKQRRGRPRAGSLGERSSFYLDEEQAKEAARVMDENPLTDNGEEDDDGEEEYYDPMEEYYRPEELPPRTTTPRPSRIPTPTQLQRGQSEPPYFPTSSAGASTSALSSSSATPTQRPYATAGASNSTPQSKRAATTSPPSASNKGKTKSYNSTTPSPSSNSRLAASKATQAKLAQNKRQREKEEEYRRSIAAYPDTGDDLMNAIPTWTQPVPKAGNWDDVVLPVVARKKGLDGHYERADGSPQQRKDEVTIAPAPGTFGFDHSKYRPPREGEENIPMDEFGTKNSAYTERDDEEQEDEDNQPPHSQSRMETAHDQIGLPTNTIPSKRASSPVPFSSYKPRPSQPEPVGQMNGDVEKGNMKVQRVDADESEDAGKGGCCGCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL23</accession>
    <name>A0ABQ8VL23_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C8R41DRAFT_909189</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Preautophagosomal structure membrane</location>
            <topology evidence="3">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018939">
        <property type="entry name" value="Autophagy-rel_prot_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09451">
        <property type="entry name" value="ATG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0072">Autophagy</keyword>
    <keyword evidence="17" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0732">Signal</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046143195" description="Autophagy-related protein 27" evidence="20">
        <location>
            <begin position="27"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="21">
        <location>
            <begin position="30"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ4497106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="31499" checksum="229626CDBD60920F" modified="2025-10-08" version="1">MIIRHLLSLPPAILLLLSCYTPIILAADGFNCVFNIDTTKFDLSSLNNEHKITRSRSTPPSTMVDSLTFNVCDHLTIQGEVAEMDRCPSDTRVCLTKINQKQEQEDRIVAVIPLGDGLNVNLTKSSSPAGLSITMYGRPYPSGSDNAKDQTFNLKLICDENASDPKFVSYDGSLAEVEWTNPAACGSEVGDGSDNDSGNEGDSKGDEEEESVGSGIGWFFLVILLAFIAYFVLGAYHNYTTYGATGMDLIPHRDFWQEVPYMMSDVVSHLCSSARPRRSSNRGGYIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL37</accession>
    <name>A0ABQ8VL37_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_291948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="2">
        <location>
            <begin position="75"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="327" mass="35807" checksum="07D18C4FF88A47EB" modified="2025-10-08" version="1">MIIPTKELDDSEYNGKLDDDSPTETGTVRGVDSNKVEPPPEYSPPNPYYPDKQKKSTYPEVASKPSDDLELKGVNFVYRHIYFDSIYATYIIDPSVQDLSQSILPGASRDDRRLGSRTGPRKGKTLKNLCLQSECGAINVGVRVLDTEIAAMATEGKRSHLPRKVLLDVRATFGPIDVRLRLGSLPPPPGLQVFPESTATRLPIKLSASSKCGPVHISLPASFYGFIFFSVPLGEIVLSTQVQKNVSWDRMLNRSIQKNSGARTVFVGDSEALRGRIEGGSKPSASSKGDTRRSDGSHRADVDGPWNGDEVHLDAWCGSVLVDYVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL53</accession>
    <name>A0ABQ8VL53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trm112p-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_228786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRM112 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21089">
        <property type="entry name" value="Trm112-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158997">
        <property type="entry name" value="Trm112p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="123" mass="13981" checksum="A402BD2976CE4642" modified="2025-10-08" version="1">MVRLLTHNLLACHVKGCTSNNFPLQFQNAQIELREADFNTDFLKNFLPKLEWKALVDSAKDLGDTSLPLEQPEMLDDEFLKNLHHVLLEIHVEEGSMTCPNCKHSYPISNGIPNMLLAEHEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLC3</accession>
    <name>A0ABQ8VLC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUZM, NADH-ubiquinone oxidoreductase 21.3 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_823507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22849">
        <property type="entry name" value="NuzM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016813">
        <property type="entry name" value="NADH_Ub_cplx-1_21kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="179" mass="19725" checksum="59B0C8262839F49D" modified="2025-10-08" version="1">MATKKAADSTLYHLSPKGFWKRFRDAIVVNPEISSGLPLQGVNRFPPPGSRPEKYSTPATKASDIAQNPYWKRDVRRAYPQLSVITQTGLSSLLIEHSTPQVVAAPAEGDTTEGSKAVSTAQDPIELAAAISKITTSTKLYSESKLPPTLTLSYPRWRPERAPDAPHPQHAYFPLQLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM65</accession>
    <name>A0ABQ8VM65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047441227" evidence="2">
        <location>
            <begin position="23"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="22414" checksum="5FB205209C99C925" modified="2025-10-08" version="1">MVYTHSVLAAVFVVGAASCALAFPVQGPSELWPHNERSQEPSNYQTSTVVARRASLDTRGGDNSSDSGSQDANPKSESSTSGPNNDKEVDLSNSPALKNGLNLFKSLRNKQPFEPGAPYPRVGGHLDRQSSKDKRARRNYFDVRDTISATSGSDAPIISTKTPAESVFAGTVEVGSPSPSNAGPTGPIELAGPAESALPHGGHHIRSYGEDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMD6</accession>
    <name>A0ABQ8VMD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046538362" evidence="1">
        <location>
            <begin position="22"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="228" mass="25380" checksum="34E30C0D8490BCD0" modified="2025-10-08" version="1">MYNAIWSYLMTLCMTATVVYAAPVSDSNNVLSSRTSHAQVGHPVSASPLPQITATILEPLYKTRFENDLKYQKATPETKIVWPTGMEVVHATMEWVMKCVYTRHVQAAGAKAVGFSSHTAHSTPSGRSVGHLHVELTNKGEGLPHIVFEFTGGPFGTKACDPYCFAQFDNVNWVPEGIVVSWSGEVIGYCGEDYGEEMRWHNMAMEIFAKWKQEKEKSVKAKSMLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMI1</accession>
    <name>A0ABQ8VMI1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047323543" evidence="1">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="21399" checksum="967D2C8CED9D6A88" modified="2025-10-08" version="1">MLPLRLFFALFLSLSSLLLITVAAPVTNASKQPNKSLGPQTYEIRLIRMRRVDGKELEITDTQEPVRSDEIWSLKIGSSEFSAVRQPSGKWKGRVITSLLGGETGILLAYATFPSIQKWEEVGLKLGDMSSTSNLEYLNVVLAALKGEKYLHDLNALWRYRDNYDNLSGFYWQMCAERGTAGGTLSHEHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMW9</accession>
    <name>A0ABQ8VMW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">(2E,6E)-farnesyl diphosphate synthase</fullName>
            <ecNumber evidence="3">2.5.1.1</ecNumber>
            <ecNumber evidence="2">2.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Dimethylallyltranstransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Farnesyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Geranyltranstransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_791559</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.1" evidence="3"/>
    <dbReference type="EC" id="2.5.1.10" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4497733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="44329" checksum="78DC798926B48276" modified="2025-10-08" version="1">MASTDKAARRAKFEGAWNAIRDELLTHFKSCGMPQEAQEWYSRNLDYNVPGGKLNRGMSVIDTAEILLGRKLSDEEYLQAAVLGWGVEMLQAFFLVSDDLMDSSITRRGQPCWYRVPKIGFIAMNDSFMLEAAIYHLLKVHFKKEPYYVDLIELFHEVTYQTEMGQLIDLITAPENDIDLNRFSLKKHSLIVIYKTAFYSFYLPVALAMLFCRVPTSYSLPSSPKPIEPYEVAKEILIPLGEYFQVQDDFLDFSGVPAQIGKVGTDIVDNKCSWCINTALAYATPAQRKILDENYGVKPTEEEKEIAKKMAAGKNGEEQGYLGEAEKRVKKVFEEIGLREKYTKYEEGVFQKLNEMIDNIDEGAQGQQGVLKKQIFISFLGKIYRRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN02</accession>
    <name>A0ABQ8VN02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exocyst complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_821051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="6">
        <location>
            <begin position="47"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="5">
        <location>
            <begin position="169"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="871" mass="97158" checksum="546324D7BEFA6641" modified="2025-10-08" version="1">MELDPAVEAQLQLSTFKGKFDVTEFVGGVSEKLIAQSKSDAGPFDPIPFIKTFEAAVDKLIAVRKEVQAKTEQMEKSVRVSEREYSKKMADLNRGFESVGNSFSGMESRMNEVSSTAIRIGEQLENVHIERQRAQAAYDIIDYYNHFSKGDTSRLDALRKEGRQGRRQVAVLLRRLNTVAKEVDLPMADKTRENIEKYCEKFEKEMLNLFDRCYRKGDPKMMHHCAQTLLEFNGGSSCIQVYVNQHDFFINNVRESKGVEDSLLWSVISNSATIPPKNEAGLTELFTEIRATVDTEAQIVKAVFPNPPVVMQVFLQRVFAQSIQQHVEHLLHRATAMSDLAYLRVLQLAHIQTSILVEDLKVYELPASGSRVPFEAGELNKTLFGTANVGINASASLSTMLETAMEELFVPYTEGQRYLERESQSLGALYASILVNFTRYHQAKVPKGKSSIFDRVVNQLSNTAATTSSGGVQTTSAQAANAILRFGGLNAEKNVVDEEPVREEDGQLSVDVAEKMLKWHAEAIGRCVELSAPNDLSRNTFALLRVLAEAISTAYIEAALETAQVRLDASDPKTEPLLQVLITLRTVDLICHLWQQYVNTALLPLASSSVTIRREMLVFNNQTVSRLEGGVNQVMHRLADTIVAWLSSQLSKQKRNDFKPKNDDISFARVNTEPCVACCDMLEKFRDSAKVNLSGKNLESFLTEIGISFHSLLLEHLRKFPVSATGGLMLAKDIRMYQDTISSFGIPSLTERFEFIRQLGQVFLLSPEILKSYITENYLGRIEPSLLKPYLAQRSDWGQFEKGFNDSGMSVDGAVSDTAKSRFGRLSVMMKELEGLKLEGLRLSEGISVGIPTLPSGFTGTFSMSSRPFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN94</accession>
    <name>A0ABQ8VN94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate esterase family 9 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_792297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF5">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="300"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="843" mass="91441" checksum="AE5E8A154D88B397" modified="2025-10-08" version="1">MIWTGLNNGTKTVHGDILLDKGLIMGVGHFGTASYGNDLTVIDARGRWVTPGIVDIHSHLGDAPSPALDGAEDENSIKGTILPWMRSLDGLNTHDDSYALSISGGVTTSLVLPGSADAIGGQAYVIKLRKTAERSPSSMLLEPPYQINASEPWDASLPPRWRHMKHACGENPSRVYSATRMDTIWAFREAYNKATQIMKQQDEYCSKVEAGDLQGLGDFPEDLQWESLVDVLRGKVKVNIHCYEAVDLDGLVRLSNEFKFPIAAFHHASETYLTPELLKRAYDKPPAIALFATNARYKRESYRGSEFAPRILAENGFTVLMKSDHPVLDSRHLLYEAQQAHYYGLPENLALAAITSNSAEVMGMGHRIGYVRKGWDADLVIWDSHPLALGATPIQVFIDGISQLESPYISDKPPAFQKSPKVPNFDKETQLTLEYDGLPPLRSIKGAELVVFTNVSNVFVRTSGTVREIYSATAIAGGIVVSRNGRLTCTGDQSACLTDAVLGSDSEPFFVDLKGGSIEPALTSYGAPLGLEHINQEPSTNDGFAFEPLSHRVPKILGGSIVRAVDGLLFDTCDALYAYRAGVTTGITAPSHYGFFFGLGTAFSTGASHKLENGAVVQEVTALHTAIGFDDTPSVSTQIATLRKLLMTPPEGPAGVWFRKVSEGSLTLVVEVHNADVIATLLNLKGEVEAAKSSQIKLTISGANEAHILAEYLGKAKVGVLLFPRPFPTTWDRRRIAPGPPLSSNAVQKLMAHNVTVGLMIAEIWEARNLPFDVAWTSLDVNGTLSKEEAFALGSVNVEKLLGAELEAQDADLVAREFTGKDFLFQGRAVGILSPRRGVVELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNA4</accession>
    <name>A0ABQ8VNA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="183" mass="20719" checksum="5C4002184B6711D2" modified="2025-10-08" version="1">MIILIQLTLNDGKKRIFVWIDESLCISFFIYFLFPASLMEQLNSILVAVLRAAQQTGIIPADYTFTASEVLEAAQQAGIISSPPANDPFPTLQGFKCFVPEAQLTDWHMNNLDLEDLLGDRISNGIIDTFQKPHRDSICRSYCSHIWTRYIPSTICSSQYSVWQSSCPLKIQLGHPTFWGRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP02</accession>
    <name>A0ABQ8VP02_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 6">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_160301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a central role as a glucosyl donor in cellular metabolic pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 6"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="469" mass="52736" checksum="3B610AB4995C5A45" modified="2025-10-08" version="1">MRSEIDKLLVTLSDPAARKGFEMEMLSFKQMFSRYNSFKVQGAKLDWAEISPPPASQLVRYDSLSRQADLTSLNKLAVLKVNGGLGTSMGIKGAKSALEVKNGSTFLDLTVQQIQHLNTTMHIDVPLVIMTSFQTQADTIRVIKKYVNDSVRLLTFNQSRYPRIFRDTMLPCPRTAEDEGRTWYPPGHGDLFMSLRRSGVLEQLLSEGKEYLFVSNSDNLGGVVDTAILQHFIESDLEFLMEVTNKTKGDLNGGTLVNYDGTLRLLEVGHVPFEHIEDFKSVFNFKIFNTNNLWINLKALKRILDNEGLNLDIIEKTINLDNGEVVIQLETAAGSAIQHFKKAQGIVVPRRRFLPVKNCADLLLVRSDIYRIENGHLIPNDYRLFQTTPTIKLSDNFQSIDEFQSRFKTIPSISELDHLTVTGDVHFGRACDLRGTVIVAATEGQRIDIPDGSVLEDRLVAGNLNMIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP38</accession>
    <name>A0ABQ8VP38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_819479</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044962558" description="Peptidyl-prolyl cis-trans isomerase" evidence="4">
        <location>
            <begin position="27"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="37"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="24347" checksum="7F459043D67137DF" modified="2025-10-08" version="1">MYFRRLSLIFLAVSLASLFCAQDAEAAKGPRITHKVFFDIQHGDQFMGRIVVGLFGGTVPKTVENFRALSTGVRKDGTPLDEGMTYKGSIFHRVIKQFMIQGGDFTDGNGRGGKSIYGNKFDDENFKLKHTAPGILSMANAGKDTNGSQFFITTVVTSWLDNKHVVFGKVLEGMDVVYAIEDVPKGQGDRPIEDVKIIECGELLIEVVTDADGNQVPLHAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP46</accession>
    <name>A0ABQ8VP46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RF-1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_762579</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="150"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="217"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="254" mass="28954" checksum="45C9FD101578D869" modified="2025-10-08" version="1">MSVSAELKASARSAYRSLYRASSSIFGGDATVLSAFRSKMREDALAYKSETDPSAYEAYATQARDIAQFLRRNVVQATKLPEEETWSIRITRDTELGDNESVKNPSVMPSNNRRTAHTENAAPAHDALQHKRPMYYSALKRASSQRKIPELKEEDIEESFVRGSGPGGQSVNKTENNVQLLHKPTGIRVACQETRSLFTNRMLARRLQSKCQQLDALENPGLSKEELKRARQRERERRRRKKAKKKIERQQIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP57</accession>
    <name>A0ABQ8VP57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_894586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="21467" checksum="1732A066F49D8EE3" modified="2025-10-08" version="1">MNLNPYAQAGWGGSSGGSGPAPSIFGALPFSSQATGPSIHEFRFTAFNPDILDCTVLGPSSNTYFRVLNNTPSQNFTLFQNREGKSIAVLEWRGSSGVVVEVRDVIRKQFVASWLQLSTDGKYRFMYAHDRTFVWVPQDGYVGLYTYGTTTPELYARLSRTDGGVTLEITSTAIRESLLECCVVATVLLQSGRSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPU9</accession>
    <name>A0ABQ8VPU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_219366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="367" mass="41152" checksum="2D685801C0FDAEB4" modified="2025-10-08" version="1">MYSMIGQPCKWGIITKGIRSRMCRNLLKHHIGVIVFLMRVEKSKFSRSRRFQAAVVGHYRFQSLMPWARFYHLRDCEGIAIRLLLRLHTPMTSTTLDSANTQTTDVTTTFGYIDDENGDLVSGIFPILSPPTGWTQGSICTDCAFHLDPSKVFNGTWSDTTHYVYDPARTVQFNFTGTSLDVYCILPNPSDPVLTSTYNLTFSLDGQPLQQIFTHKSDLSNVYMYNTSVLSLEGLTSISHVFTMLAASTVVNSSLLFDYARYSNAASSPSPSSNPGKAHTSGLPIILSVVLGSILVLFIILLFLYRRYRRLRPQSNSEPFHFVEPYIHPQVTRFGSKSVHPGSFGSSEILEQPNPDDPPSYAKIDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ04</accession>
    <name>A0ABQ8VQ04_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mog1p/PsbP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_864665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046893484" description="Mog1p/PsbP-like protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22225" checksum="3DD2ED392FC36AA3" modified="2025-10-08" version="1">MVHCKSLLAALVAVAGSSFALAIPIQGTAGVFSMPENGVPRTNFIPPPASVNPLYRRNVIDVEEAEGIDIDSGEEPYWRFHHDEKLIPVPVEELPEQLLSASPHTGEEEVRLSLDISRSSPSELSRRASNSVGDKELTEAGTLTYPDTNGVYHNIKLVGVQKLKPDGTKALKAYISSISMNNGGVLLESDYSRIYNQLTILLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ81</accession>
    <name>A0ABQ8VQ81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047205967" evidence="1">
        <location>
            <begin position="29"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="21120" checksum="01EC5BE58827A0D4" modified="2025-10-08" version="1">MFSSHPFFKIMCAVLGGSILLVLEGVHATLPSDISIPTPTFEPVYDATLLLVPGVTQDLVAGPFGDRAFIGFLGGNLTNYATGALEGQILAGFGGEFGIVSTNGMFYTDVALAVQWSDDDKYAFFRVNGIGELGNSTYATSYTRLETDSATRQNLVDNVLLISIVVETEDAPSNETIAYFRLFVKVIRFKAVATPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQD6</accession>
    <name>A0ABQ8VQD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_916110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="281" mass="31622" checksum="6422AA1962B79C79" modified="2025-10-08" version="1">MLSHYRLYTWVSESIEHVLDHPSSNWWSHLIRAVAEVVELGIPGMFQFDSLEFFPAIDPPKSYTWLFQKRQNDQCTANTLLASRIIFHWLGLPMESDDRHRVQLLFLKSIMDSCRTPSVLLLDEVWNAYNAPSHLCSIGIKRALPSKSAMKKLDRAFLEHPILGCERSSEIDELFTALHSAHCLFIGLSTTSSASNPGMLAPSPQSPSLSTALPASSFIQTLAPTSSITSNLPLQNPRVTFFHDWLLEIAEIYVHSSSLSQDALTIEQRRILNNPDSSCPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQY9</accession>
    <name>A0ABQ8VQY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 20</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mediator complex subunit 20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MED20</name>
        <name evidence="5" type="ORF">C8R41DRAFT_123576</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the Mediator complex subunit 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013921">
        <property type="entry name" value="Mediator_Med20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08612">
        <property type="entry name" value="Med20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="300" mass="32992" checksum="4E94C0D9329097C1" modified="2025-10-08" version="1">MGLTGLARWINAPPDGLLAIRKNIQENHNGFLKGPWNLAVKSFRSTLSQTPGIHLPLERTMFTLQMNDNVFVLLEDPLAPTRADVVQAIADKTAPPNFHPTHYRTTFLTLNPPGALEQLLAQLKARWVPVRQTSTNNAQRGQASGHQLLIEGQVFGIGSDWLVRAGIVTMTGGEMKGMLLEAEYLPLPGLNVGPAADGTSELLSNLLTSVLPNVPDAKTVAVTISEAQWEDVLWDREEDEKAQKEVAQAKERESNGENDDIFVYGLEDISIKRRGDWTGVDRDRRSAFLIIGALKSEGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRD7</accession>
    <name>A0ABQ8VRD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BRCA1-associated protein 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_816898</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12717">
        <property type="entry name" value="RRM_ETP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034931">
        <property type="entry name" value="ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="238"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="275"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="569"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="454"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="596" mass="65969" checksum="CF612ABAAE3BA057" modified="2025-10-08" version="1">MHGFHVRIVLNTKVQSSFNISIPNTIFDKLPVHHPNPTNRKNATFNPHQKDYRFGPIRIDWMDSYMPASTSSTGKEKDRGKDGHAVAHFVANETVSGSTNLPEGVIHVYRENETPTSQISTSRAVTDSVILGILAVPSWMAPSDLLTFVAPAAETISHLRILRDCVPNRSIALIKFPKPEDASEFIEAYNGKPFNSMEPEICNVVHVLSVELHAEDTVSQGVAQFVGSQNNMYELPTCPVCLERMDMAVTGLVTVPCSHTFHCMCLSKWGDSRCPVCRYSQNLMSSHPSSTSTSTRPTKIPFANPSTANMSACAACSSTTNLWICLICGNVGCGRYGRAHAQAHYQSTTHLYALELETQRVWDYAGDGYVHRLIRNKADGKVVELPSAATAMSSSPRESGLGPSAADALSAEKIEAIGIEYSYLLTSQLDSQRAYYEDQTAELQIQVGELRGLVERLTNQSEKEQIVSTEAERERQRLDEERIIELLKAKAKAENRAEKMAELARRLEKDLREERAVTEGLMSNLGKMKEKAEAVDKDREELRSKISELEDQLRDVMFFLEAKTQIETGGGVVSEAAGGSIEMPPSGSNKKKRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSC0</accession>
    <name>A0ABQ8VSC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial zinc maintenance protein 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_815044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="46124" checksum="323944A36639E6EC" modified="2025-10-08" version="1">MLEDVSIPSQKSLNFRNNLAHLVSPLRRVRPRVPFFRLAAHRIPTLWGLFRGLLRAAPTEHIYHRVRVLFEQNRHRTGTERTIQELRKGYKWLETFKRAQAGDVKTQAVIQRYDRFLRFKAEKEHWTELVLKEVEWQEHLKNRPIFTGGFVHPTVFHPPFPRMKPQPMAISRIIANRMKQRERRFSKMEELTRMRDMVRKEQHLEQEIMREARRTGEQFEPVFEGEDWSTPLVQAANDIYANVKATAERNLRPFSPELIEQVRAARRNKIANKTKERERERRGEILRVTRKRWRKGLTPHLLSTLSEKQKREELIVQRSIAEVGYVGLLKKRKGWKLKEPKPKVEGKYWSVEDAEWIGKEEREAAKKALLAIQEENERRRESSSVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSP1</accession>
    <name>A0ABQ8VSP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_62901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="952"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1067"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="958"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1109"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1166" mass="131843" checksum="06B04867883AD647" modified="2025-10-08" version="1">MSYPTALRLDDAMDNTTDAIVRAGKLLKRQLEDAQPTLYSDLKPWHCMSIIENNEQWQKLALQEEYQTIFRSVYEQLSAGTSISTLLNPSSVTLSIREPTRVRIEDVVEDFLKSLEEPMKGYIQENRLPEWTLPETALVGLNESERADIVAYVHSLAIPARSDNPQRPDMLLHNLGKLADSEVADSIKRIFEIQEPCLLLSTSGSGKTRTVLEGLTQHWGFYFMCSCDDSGLGSRDLSSMINDGLPRDDRFTSDLLSVEDNGREVCLSRNRSIARQHFSEVLLARLAIFTAYLEVVFGVDAVTCSEDDLKKKWLILQLKPRLGNIADIFNEFSRKLYELRTPRDTLAPIADRYSQRILQLLRTRGIQCIDLAIVLDESQAAAVKHKSAFMSGPDGPSDSVIWLANSPANSPANSPENSPANSPRENVARDYRPVLREIVREWLEDPCLDFESSLDFRTKLIITGTGLERTTVKDAIASSVLKQRNFYSTYITNSLDDRKAHRCYLEEYLPPQFVQQSLQFEHFFDRIRHWLRGRYRFTAEYISLLLQDGFRRPHTVLNCFINAAIGCQPTDMCEEFMHTERRFLGTIPEIRNFPFDFSRLTEMKRGRSPLVANLIQYVYKYFMTSMPPFAFTAREIEFVKHGFARYTVKTDEVVQMEGASEEVLPMPTIHISEPLILLALTLWANRNHDLWIIGPLHYVLTTEITNHDVVKGNGLEKYVAYYFATVLARKEGCRLGEILHFHGRTKLMNSTAKLVAVNVLRNGRDTDESIDDYSSATILNKLNVVPPAPTKGDVISEGAFISCTAETNVPDLSHCTSVLGRKTQQPEEVLNWLLFRHRNAICFPDNHFGPDLIFVLKLLDPEPTYIWVVVQCKLRLSTKTLSKKSVQDSLNTLAPTKFYVDKNGEPYSPQSLPMLPERTLEAMSFLPHRNTELAGPYSVLRVICPFPAPVELNRIPSQDDEEDEDEDDEDIGKKREEGGQSVTDAGRKFSLCTDPDDLGHPLATLNIEKMINVMDQFIPENKLAAILGEKGQKVEYAAALANKRAIALDKEARQYIDQRKLTKAKGINESVKRTGGSSKKRIERKKSTAGTAKDGAIGKADAKRKRKSTFSTRQPVESGSHALSTGNAEKKRKRTTSANSVAETELAQRNAGTMKLRTLPQKSRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSP6</accession>
    <name>A0ABQ8VSP6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_789256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="543" mass="62846" checksum="2FADFC5BF635F09B" modified="2025-10-08" version="1">MSSSEDGQARFLSEYLNDVWSEITTDQQLVSRQRCALLLKRDPNLRKLVQKAYVEENSDILKGYDLPSHPRAMVYYREELCKVFDVLETMRVPLEKVADGSTTYNSLKWNLRGDSSISKDIVEHIKRLNIPCKYPNSSPLLILHENGCFKSMHNLNKRLNHIFTPKKNTFLVNSSGTGKTRLLYEGLCKHWGLFLTAAVDSSGLGSVDVQYIIQDHLPYDRSFTAVPRDEDANPNSIPVLTNLALARRNSSGILLARLLAFKLYIELVAKGEFQEIHKRRWFLAQIQPYFTDGSDVFSLLQCTICDSMADDALLNDCIAQCIEDIIKLFDRHSPGSNFFVVLDEANAASERHRLAFRSVHGPHSVLKEIIQVWHSHLHATPFTMVVAGTYIPDIYFKEDKWKEWRWISSTCAFDNIEDQRAYILKFLPHDFASSPSGQHLLHRMWVWLRGRHRMTSAYILTLLENGYQSPHYLLNRYIHMFTGFWPFDGGEFIRAESPRSCREFDGIPMKQLEHVDKIRVNMQHLLMKLHCRLSFHSVTISRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTA2</accession>
    <name>A0ABQ8VTA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine dehydratase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_814523</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="3">
        <location>
            <begin position="312"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="430" mass="46620" checksum="EB3B5AAC1FAE7069" modified="2025-10-08" version="1">MHQTETPFDFATLPSKSKLVGHFVGKGLDELRTPAMIINRKVFAENCAAMHSKAREWGTAFRGHLKTHKTVEGTRLQMISTADKTNAVVVSTLMEAWEVARNGLFKDGTVKDLLYGLPVAPNKVNDLSSLWDDVAQDGGIVRLLIDHPDHIKFLEECESKRQTPRKWSVFVKIDGGQKRAGVSPGTLTFENLVKALLASPAISIYGCYAHAGNAYASTSLDQASSFLSAEVESVNAGAELIMKIASAMGVELDNQSLVLSVGSTPTAHAASAETKAKLSSLLHGPLELHAGNYPMLDLQQEHTNLIDRSKVAQRVRVTVVSCYPGRGVNGTDEVLVDGGAIAFSKDTGPSGSFGEVIGTKWKLGRISQEHGTLTREGPAENEELKVGDEVEIIGQHACLIAAAYPWYYIVDSDVNEGKEVVDIWIPWKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTB0</accession>
    <name>A0ABQ8VTB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_863945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="224" mass="23815" checksum="07B1658BD9729512" modified="2025-10-08" version="1">MAKTYVGAGCAGVEAAAMGEEDEVLVEVAAEEEEEEELVVVASVEIDVDEVDEVDEVVDDVEDVEEVVDVDVVEVVVVEVEVVEVVEVLVVDVELEVDVEEEVVEVVEVESVVLLSVVVLLEIEVAVDKLVSWLVPELVSDCVLDIEEAVEVEVGVGVGVEVRVSEELVTVVAVEARDSEVLVTAEVEISDVLISVEVEDSTVLVTEVEASDAESEVLVGAASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTY2</accession>
    <name>A0ABQ8VTY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_609641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="916"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1108"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1653"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1869"/>
            <end position="1907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1985"/>
            <end position="2025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="801"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1657"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1683"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2016"/>
            <end position="2025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2025" mass="219537" checksum="50391B25094BC4D6" modified="2025-10-08" version="1">MRNTLPLLSRPTDALSHPSDVPSIRLVAATPSASGFLSEASTSLEFSWTAVPSVPSPLAPKTDAEPRKRLVPKKSKLGLLGGSSKDRQKDRGKDLSDVVRRVGGGSTSRRAGGFEIYVDPTDPEIGEIVMVKKKKSRAGLDGLRWGSGGGALGEVTNVPSVPQPMTAVTKIKAEEKEKWWTLGRGRKDSKEKEKEKAREKSETRPPPPRSKTPEPFKSVPETQSRARFNSLDSGMLLSSISSPPLNSADYNSRNILSDRQRTTHTLNKECQAPGTYSRSATPTFGGLLAPPTQFDGLEPSQGNPNQNSIALRAMRSIARIGSWAQLKNGTGPGDETFPKELEKKGKPKYKEKDETKKKSKKDKSEKEDRNKTQRIRNSTSSFEAGALTTSPEVKALLGKKKRSILGLGLPSTMRLPAVRSGSTTSSIGATGGSDNNRLSVDSAVAIAARMRSGSTMSTGSSLRPLSTTSSTSCISSSSSTASVRWDEAGLETVKELRRKEKETKRQSIEDAEADAKRKKANHESRRHSEGRRRTPITDVFPDAQEDLPEPTAFVRTVSDGAPLLTLEEATSDGHERMSEDELSTPMRYARPRPLSEQLIGRKRPQGIHEEDGEGVISILSAATNDLAQLINHLDLEATPGATPGKSPDASPWRRTAGFQSSDTNQDSPTKKTLRGTMTSISSLRPYAQYRELTTAKPANSQDLLDQQIAPWPVLNSYLPQNEVPAKEASSVTTSKVRGHKRTMSPSGYLPEASPPPPLRPLRPAKSRNVVASFNLQPLGPPPSIDLPVQPLPPVNAGRAPSSLTFGSRSSSRGGESSISSLNDIHSRNPVFRPTHGHNRNRSSLLSSQPGGGSQGSIPEENFTTSRPLSVEARRQLGMKGTMGGSDVSAYAVDDLDTSDPDSDIPDELQVILANQSPRTSVHSIEDHTSFRSLDSPDAPQDVSSLVDPESEFESTGGREVVDLPVFHLIDVDDNHADLDDMLDVDEDDTKKSFDFTGELEKLNESGGSDRASFVEQLEKAFKTPAKIDLRYDFGGQGGLLQVDIPPLPALPSIIAMDSSKSVELTDSSISSQEAHYGASTQATSSSLEIFSISRLLDVKEATLLPGSDSISSTGSQDLPDASAPKVLKSSVSSASRPSDGELNKSFKFGGFTKSLSQEIELEKPISFADIIPSPSRVRALSNASSFVDDSVINSIIAKASEVPAARSGPNSSTGKRNASDNSINAITRNITYRHSRHDSTNSFNGFDSFEEVRRGFEFHDYRPSFYPPPVSNSTGSRRNNHSKQESMMSFASISSYGHVVNAGVPDPFDYGLPSLRERPSSEEMTSTSFSMSIDDTFSFLKHAPPRKRVESDASSFYFNASSRGHCRRESNMSVVSQGPPISLYNRSFGHRRNDSSTSVSSMAHSYAIHGANGGRAAWAHHRQDASIDSVDSSQFSARQLGRPGIGDKMFDTAANFGAPLTSISASPPGSSYSQSCSSFDSIMDDEPRSAVDDSLFDKTGHRTSFSSESVFGCDGSSRYAQGHLLPQNAFRPVSYLSINSIHSPSKDDDTMISMIGGGHVRRRSVGSVIEASPIVRAVGHLGKRKNAALGSVKDGSDKGHVRIIEKASIDSTSSSKFGGERMIRATKGLLERQSLEESCLIAEGEDLSASYSIPVFTRPSPTTRSRSSTCTSSSSGVDTPPLSASDGSSISGGSQSSIDLAQINRILANATHPISNIAWQRDRARARGEGHRRRISQARMSRSSVYETIEEEMYSPGDTPLSQSTASKKSSPTVIQPVFIVDPADNASIHSIDSWDEERGIVALKRYHELRSEAEYTVSESRRLWVDTPFSIYALQNFDPPRHPSGMQALLASSVESYGPLPMDLRVRRKRTSSRPSPYPQGRSVRVSLSPDYSRPMFSKETSPRNYNATHNPPLPLNEVTAHPNIVSSSPDAVSLVSKKVFYRETNSQEQIMRKQENVRPRVASTTRRTALGWSKRAAKVSSELKENNSTFGQGIGMTPGNNSLRLSRPRPRGRPTPARPAVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUD1</accession>
    <name>A0ABQ8VUD1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046521">
        <property type="entry name" value="DUF6698"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20414">
        <property type="entry name" value="DUF6698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="517" mass="58833" checksum="FBAF551344F4CFA3" modified="2025-10-08" version="1">MSSRSHRSKSPSHSPSPSHRSHRTGSGRHTHGSPSLTDIRGQSTDHDYHDTRSSPPPRRIRSLQQSKSHSTRDNCLTQDQERIRDLERQLASARNSKEKEGRKRKAPEPLDNMSAMRRGRAIPKLVAVYEDIHTLLAQYDEYRHKGYHQLDSEGDDDDIDIEEKRRLQRGYSGIMTLYKTVYPDFLKKIKEPGSAHIIRELQTGANSSRAFDTSTVMKFVGDILNEEVRKINQAKLKEYQVKLRAYTENVTTGDSASDFPTATTNTMAEPVLERVEEFCTTSRDNRGLQNDVTGYLLCPAEFDWNDTAVRAAVRAFDPNYDFASSAHARCFYKDEEFDPDDFDKGFLQSYLLVQVYRLMFTSPSSTKDQPQDVENLPASKKKKTTGTNHRGNVAQIIHMNDVKPRSIAYAAVHLHFALSDASQWTNSHMGYNYLDLWNFIVDFFEDPEGEEEEQRSKELLKWWNDRIFTGTRAAANSRGTKMTSRKQDVSKRLRVASPLHDIFSNGTGAAPGPASST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUF5</accession>
    <name>A0ABQ8VUF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C8R41DRAFT_907879</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16451">
        <property type="entry name" value="mRING_PEX12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14483">
        <property type="entry name" value="SPX_PHO81_NUC-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="22" id="KW-0649">Protein kinase inhibitor</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SPX" evidence="20">
        <location>
            <begin position="365"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="18">
        <location>
            <begin position="698"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="18">
        <location>
            <begin position="731"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="18">
        <location>
            <begin position="799"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="18">
        <location>
            <begin position="831"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="18">
        <location>
            <begin position="864"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="21">
        <location>
            <begin position="1149"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="417"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="418"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ4499985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1445" mass="162109" checksum="238B832A88BEB84B" modified="2025-10-08" version="1">MEFFNDVGGDPLKPSLFELVAQEQLRDLLQPALKYVLSVFAQRYPRYLLRIVNKHEEFYAFFMLFVERHYLRKHGASFSENFYGLKRRRRPYIEPERAKAATGGVPEAERLRSREIRRSLLFLIGLPYLRAKAQDYYEELGGGANSDILDEGMDARQLRALTDQSYKGWLRRAFKAAYPWLNTSFEVWLLVCNVAYLFDQTPFYRPWLSWIGVDLRRLGLEDFRAASLAARAKIPQAKPKGILFRFRRLISTSPHLLFDSLRLLLPTAIFFIKFLEWWYSPNSPARSLSVSPLGPAVPPPNLLLPHPKGIGFDQQSYGICPLCHKEINNATALPSGYVFCYRCAYDHVEKHGECPITLLPAKIWQQFGKHIQSHQIPGWSPYYLDYKFLKKIISSLEAKRPASESAAFALGSRPGDIPSQTVQTATTIVSRENTPGAPPLFSTSEHDEDRGPEFQAHKAAFFFKLERELEKINAFYLQKEAELKLRLETLLSKRRAAAMRGLPDTVDGTMQNHVEWNAVEEGFRLLERDLGKLQAFVEINATGFRKILKKFDKRSKSSTKELYLSRQVDVQPVFNRQLISELSDTVASCLLNLTDLSSDSNFEGRAANDIFTQQILAERTFIGPLHDLEKNLRKAVASADQSAIVDCVHYSEVVIGGARRNTTRILWSVVVEAPPDLADLILTSLSSPFDFDYVDDINGRTCLHEAAIAGALRLVKLCINKHVPVDKADAYGRNALHYAAMNGHAMVCQSLLETNVSLNRLDIDNYNPLVYATLRGSVDCVKVLLDHGNASPQPTTPNGDLIPLSLASQSGHVDVVQLLLERGAQCLANSNGEYPIHLAARAGHVDVCKLLLNHIGWDVPDKYHEWTPLFHAARYGRDQCVRVLIDAGARVNLADELGHFAMHYAAWYGHYQCLTYLIEESARVPVLPTNTKILERSPGSDDPMSVESEIDLIPSLSLPPPIMPHRVYGHNYLDRSHLVQVSIGHSLSQNRDFSGVRLHHRLISPAFRDEYLLTTAPLKLVMTTAPQVTSAPYSISLPPQDERGVFIFQTPSLDSLTLEFSVYPNFGTKTIGCAVALPSLFAGMESNQAFTLPILDQRLHIVGEVSFEINIISSFDGVTLEVGGDVETYWKSTGISIIPHSLSPWPQRSYLIGSAQTSPSSQSLPTTSSQASTISSVRGKFLTVVIQVTRDLQPVVYTDWLLPDSDFDLSVCDVTLEQFESLAKRSGRNIDEMKVSPSSNLPALTSQAMISLVRLLKILPTTVGLCLEVVYPSRALREKLNLSRRLDLNQVVDSVLKTVYQRSIPQDSRNNRRRIMFTSFSPDICAALNWKQPNYAVFLASHCRRNTDRHPRPIRFDSGDTQDRRLLSLGSTVEFARMNNLLGVFVDATLLVQVPSLIHSIRNAGLLVGITETSEDLTSLSNGPNKESVDAYLSEGVITFTDHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUN0</accession>
    <name>A0ABQ8VUN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_106484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="782"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="853"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="853"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="905"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="951" mass="97976" checksum="48CE7B1096EC8ACA" modified="2025-10-08" version="1">MKRSSEALRLTRSTVISSSGPLGMYLKTKGSIEWEVAVKARPEKTSEQEREEIVPAGWRILPKEKEDEKKVEVPEMKRKGSSILSSFFGRKAEASPTESKEKKDKEASPRPSFASSRNSVDSKSGTANAESSSTDKLPTSPVSAPVPSTSTVGASTSTTPTPSTYGDGGSPDLFHDAPTTTPAPSAVSRFLNRFSSSSRSRPSHSRQNSNTSLALSTDDLEFLQDIVPSASDIDHEHELVQTGSNELELNGLQKMINSAPLPALLAPPPRAPGRDPQQSQSQLSSPRSPSDDFITWRNASSDASRQNKNFDFASSSSQILTPSPALPSQIQTAITRSSTPSSFALPSSTRSSSPGLDMLSIAGSSVGGRASQLTSPSTGMNALGGSAISRPSSSSAMPNIRTTSSSSSSMTMKRPTPVAIMSQSSGSSSKSPESADPFSFLPPPPSIRGGGKATSSPSLLIDDELPRASSSVSGVSSIPAALNIPSTSATAAHLPQNPDDDDFSDFLSATPTDVVQPPFSASTLFSLSSAQPLFSAGTAEFNGRDSEGPSDAFSARYDNPLNTSVSSIASTNSVNNVLLSSREMDPFGDSFDAFNDFASSSSPVQRDTLRTPSPPALPDKSPGKLAARRAFGAEPTSAGVSRRASTGKKTTGGSGVGGRIPPERLNLPAPVSSSAYSRHWGSAAHEPSPSVLSGNSVNSASPLVASSSEPALAVTPASSPSPKTHQKRVSKEAHQRTRSLVEDAMARSGIWPSLAPSAVSSTSGYGFGYGAYGFGTAPPLSPLPPILSPPPESSSSSKNRGGDLLGAHDDDDDDVPLASLAPGSTYGSVPKSTIGSFTFATQQTQAKAGLIPSISSMSSSPPYSTNGPNLNRNGTLPPIPLPGPTPSSQQPTLLMGFGALGSGPGSSSSSGLGSSPAPGMSPQFGATLASSTSKTTTGGLSAQDLSFFEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV96</accession>
    <name>A0ABQ8VV96_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="452" mass="51153" checksum="5F1A09B77C4CFDDD" modified="2025-10-08" version="1">MTTASEPVANLLSIPPEIIHHILVFCQPTDVATFAKVCRISFDLVYSGNDQFLWRELFLNNYDDPRKAIQTLVVDEAPAEPLNWKDVLQRRTEAELVARRAQNVESHERRRALETFVTAALQALPAIKNSEEKEQPSSNLQWLDRVLRETHMLSQPVLLTDSDSETTQLRSRLRAYVSLTHDPSDEEESTKVVAARRIESRCFVYDIRNYKPITHWGPFLANGFVNWQHIEHLGNVVLTNLRELPGSWATTVPSLGLENTQAFSAPGPCSDIDWAGVEGTWRRYVCFMDYRDLFAFNYSNVAHGPRNAEFFRDARFREATRLIEIKLYLVSRSQLRFYTPSPDLEDLKTRYPTLFFCGVSRGVSGNEAKVEGNVCIGIDGTIRWTFYDLIQGAVHDLSTLWCSKGVQLGGIASAAGIVGSWSTSVHDQGDPVGPFWLWKVPPSHSGALMDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVK1</accession>
    <name>A0ABQ8VVK1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA polymerase epsilon catalytic subunit</fullName>
            <ecNumber evidence="15">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_811185</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA polymerase II participates in chromosomal DNA replication.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05779">
        <property type="entry name" value="DNA_polB_epsilon_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05535">
        <property type="entry name" value="POLBc_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013697">
        <property type="entry name" value="DNA_pol_e_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029703">
        <property type="entry name" value="POL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055191">
        <property type="entry name" value="POL2_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054475">
        <property type="entry name" value="Znf-DPOE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08490">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22634">
        <property type="entry name" value="POL2_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22912">
        <property type="entry name" value="zf-DPOE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23250">
        <property type="entry name" value="zf_DPOE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01159">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 15" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 15" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="11 15" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase epsilon catalytic subunit A C-terminal" evidence="17">
        <location>
            <begin position="1524"/>
            <end position="1918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM01159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4500371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2237" mass="255550" checksum="0CC2D2D818A4E1C7" modified="2025-10-08" version="1">MARGRGFGLSSARGGNRGAFRASSYRGGSWRGRGRGKGKGKPEDAPKREDDGTQLAERFEAVKVSDEIDEKLGFALVQEGVVKEGWLVNMHPTLVKDADWPSGKAAVDYYFIQDDGQMFKCTYQYEPYFYIACKSGMENSVEEWLNKKYEGLICRIVRDRKEDLKLPNHLMGHRRLYLQLCFRNVSDLLNVRRELLPLALANGAKRDAVDAYAEVVNATSTGLADMDIAFEEEGWGNAGFSRNATFREDAREAIIDIREYDVPYYLRVAIDNDIRVGLWYAVSFTAGQPDFRHIAERVKRADPVVMAYDIETTKAPLKFPDQATDQVMMISYMVDGQGYLITNREIVSEDIEDFEYTPMEGYEGPFIIFNEPNEAETIRRFFSHIQDVKPTVIATFNGDFFDFPFLDARAKVNGIDLYLETGFAKDSDDEYKSRTCVHMDCFRWVKRDSYLPQGSQGLKAVTASKLGYNPIELDPELMTPYALEQPQTLAQYSVSDAVATYYLYMKYVHPFIFSLCNIIPLNPDEVLRKGSGTLCETLLMVEAYRGHIIMPNRHEEEHGNFYDGHLLASETYVGGHVEALEAGVFRSDIPTDFKITPSAVQELINDLDAALTFCIVEESKCSIETVTNYEEVKTAIQLALEAMRDNPKRTDNPLIYHLDVAAMYPNIMLSNRLQPDSMVDESICAVCDYNRPGKTCDRRLEWAWRGEFFPSHRDEYNMIRHALNQEIFPSKRPNGPQRRYADLSPAEQTALLHKRLGDYSRKVYKKTKDTKVENRESIVCQRENPFYVDTVRRFRDRRYEYKGLLKTWKKNLDTVINEGRSLAEVDEAKKMIVLYDSLQLAHKCILNSFYGYVMRKGARWHSMEMAGITCLTGATIIQMARALVEQIGRPLELDTDGIWCMLPGVFPENFKFKLDNGKSIGFSYPCTILNHLVHAKFTNHQYHDLDPETGEYKIHSENSIFFELDGPYKAMILPSSKEEDKLLKKRYAVFNDDGSLAELKGFEVKRRGELQLIKHFQSQIFEKFLLGSTTEECYKAVAQVADQWLDVLFSKAAALTDEELVELIAENRSMSKTLAEYGGQKSTSISTARRLAEFLGDQMVKDKGLACKFIISAKPIGAPVTDRAVPVAIFSAEESIKRVYLRKWLKDSSLIDFDLRSILDWSYYIERLGSVIQKLITIPAAMQKVSNPVPRIHHPDWLHRRVAGTIDKMKQNKLTDFFRLATDVEAQEEETQLMDIEDWGGEGPSTQTLLAPSEPRFVRQDIPEPGVAEEDKALPDPMISYSAWLKAIRPRWKRRRQGPDPRSVVVPSMFSNVKVRADRRWDIVQIRPTATLGRYMLWLSVDSELIPLPLRIAREFYVHLRTPKEEIFRTDFYSYEKVSRNLPRDLPCINLYKITVREDLYREISEHFIDLTNDPNVDGVFELQVPLVVRALLKLGRICESTDSSMTLNRAEAIGFDLYQLEAPSVSGNSKHRYLRGGKNQKYIFIYHACSANAPLHVFAVFFPSGLVKLHIVDPATRRQAIPRLREDYTEIKKKRDEHFGSSSFVYPDTRDFTTTYHSTDITALKAISRELGVAEDQNYIIVLSSSKDNSYFEMNVPKLARFPVLSMAKAKSAHTLDVFPWQSHVVGKMLNRYLAMGGWLDRSMALSEYYDIPLGHIEGDQPLQLSDITFARRLVQQDMVLWWSSSELPDLGGMETDKRPTDDLPKTEFTMPGAYSHVSLEIAVRNLAINSVVHSLVINELEGSGGSTAFDSVSRTLDEYAQGDGQKNISLGESNVPVQTFSILKAMVKAWLTDRLQGELEGAECPSVLTVDHFWRWISSSASNMYDPSLHRFVHGLMRKTFVQLLAEFKRLGSHVIYADFSKILLATSKPPGTAHAYATYINTAVTSHELFQHIYLRNDCFYDYLLFMDQANWGGIVCENPLALEPPEELSIMMKLNIAEFLPRPAQKEIISIIQYFIVSLFKIRQKTNEMARVPLRPLQNGDPPGATQHDSQMKDEVENVRQFIAGKLTRRMLRTVGNIQEQYREAMMNEETAVEWQFPILPGSHLHMSNPPLEFIKFACAIFQLAKENHVEIGLVKRNALDLIGVKEFASEAIFRNPCEPLKLFNVPCKHCDALKDFDFCRDPELLPAQGETGPPKWVCFNCKGEYDRTLIEFSLIRMVWAMERNFAGQDLKCSKCKQIQGDYVSRWCHCSGSYQLTIGKAEVKRKLKTVVNVAIVHSMNKLKECAQMMLSNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW59</accession>
    <name>A0ABQ8VW59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43383:SF2">
        <property type="entry name" value="AMIDOHYDROLASE 2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43383">
        <property type="entry name" value="NODULIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="271"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="440" mass="49515" checksum="D81001036BC99D8E" modified="2025-10-08" version="1">MNVHNSLDLLRKTAFTFPAIDNHAHPLLRSQYRGKVPLETIISEASSELALQQEATQMIACFRAAAQLSKVLGAEQVIGQSLWQQVKQQRNAMDYDELCDTFMKACGIQSILLDDGLGGVSEWCEDWKWHRRFGCDTKRIVRIEIEAEKILLPLLQPLLTSESALQNPSESIDSGLRNQLQSILAEFFQQLNASLTDSARNPEVVSFKSIACYRGGLNIKPRAKIGISLAQTEHSYDYVVDSLFQVLLHIKNTGSIRLAHGAINEWIVHWALRVAGENDIPVQFHTGLGDSDISLLHASPAHMQPLIKDYPQTIFVLLHAAYPFTKEAGYLCSVYPNVILDFGEIFPMISGSGQRSVIREVLEICPTNKILWSTDGHWHPESFYLGTIQARQALFDVLSEIVLAGELREAEAVQIAEQALFWNSERVYKLEIEPDMNLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW88</accession>
    <name>A0ABQ8VW88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MT-A70-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_914147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045123">
        <property type="entry name" value="METTL14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107:SF0">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51592">
        <property type="entry name" value="SAM_MTA70L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="662" mass="71259" checksum="FF07CD396BA21E81" modified="2025-10-08" version="1">MGEFSHSTTEAISSANDLLAAHSALVSRIRQSQQNHRRKLQSIQPPPSLELIRLPTIRSPLPSPSSSSPTENSPIQSYNNAPSMRLDLPPAKRARVVRYKNYVPEEETIRNDYSQRYVDGGEWPQNWVLGADPEHRFEEYPKQQRLLNLKKASVANYSLPPSYLSFSELNSLTPSKFDVILLDPPFSSSFTWDHLQELPIPALAADPSFVFLWVGSGAGGGLERGREVLAKWGYRRCEDVVWVKTNLTSNKGPGTDPPTTSLLTRTKQHCLIGIRGTVRRSTDSWFVHCNVGEFGFPSLTPYLVRGTGSLFLFSLPVLDTDVIIWEGDPCDPTRKPPEMYTLIENFCLGIRRLEIFGRASSSIRRGWVTVLGQVEEDQLHRTHGVGETVFVDDADGGEATKWVREIWETRIKEMVNGGKPVVPMTADIDALRPKSPFRPGAAGTPHNGPGGNNVGGTMGPGGVSMGMSNSAAVGPRMNISGGNRGAFNPHGSGVMSAPGQNQLMGSQPMSGGRMGMNVNMHALGMEMGNGLSIEGMIGAWPGMMAGMSNMGSLGNLGTMGNMGIGNMPGLSTSGMGNMGGGMGMGTNNSLVDIGGMGLHAQPGGHVAMNGMNMFNPAMGNMGWGEQGLGMDSNTWDDNMMNVNMNALGMNMGGSMPGMGQWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWH3</accession>
    <name>A0ABQ8VWH3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_952133</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00238">
        <property type="entry name" value="ERp29c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02998">
        <property type="entry name" value="PDI_a_ERp38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1150.12">
        <property type="entry name" value="Endoplasmic reticulum resident protein 29, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011679">
        <property type="entry name" value="ERp29_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036356">
        <property type="entry name" value="ERp29_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF11">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07749">
        <property type="entry name" value="ERp29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47933">
        <property type="entry name" value="ERP29 C domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047009602" description="protein disulfide-isomerase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="122"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="40385" checksum="FFE6D63410B588A8" modified="2025-10-08" version="1">MKLSFSLFVAALLTSASASNVLELNPDTWDDVVGLGKPGLVELQNLAPTYEQVADAYSHVKDKVFIAKVDADGIGKELGKKYGVTGFPTLKWFDGKGNYEPYESGRDLDSFTSFITGKTGVKSSIKPPPPPSYPILDYSNFDEVVMDPKKDVLVTFTAPWCGHCKAMKPAYEKVASIFETENNCILVNVDADDKKNEAIKTRFGISGFPTIKFFPKDNKDGIAYEGGRSEADFVDYLNEKCGTQRSVNGGLLDTAGRLADFDVLANKFFTAPADLRDSIYKEALTLSSTVGDVSKHYLRVMEKMVNGTEAYYEKESKRLASILKKRTLAPAKLDEIKIKSNILRSFGEKPVEDQNDGNIRRATAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWL1</accession>
    <name>A0ABQ8VWL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2 small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2A</fullName>
            <shortName evidence="5">MOCS2A</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfur carrier protein MOCS2A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_750885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaD family. MOCS2A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00754">
        <property type="entry name" value="Ubl_MoaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03051">
        <property type="entry name" value="MOCS2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028887">
        <property type="entry name" value="MOCS2A_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359:SF1">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="1-thioglycine; alternate" evidence="5">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycyl adenylate; alternate" evidence="5">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="99" mass="10635" checksum="CB8826E51E44038E" modified="2025-10-08" version="1">MSSTSTSTAHITVLYFAAASTTLGITEEKIPIPEKGFDLSQLKDLLVERHSRDNPTLRKILDSSQWSVDAEMVGDDEDLTKVELGDGVEVAVICPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWS5</accession>
    <name>A0ABQ8VWS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_751346</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="104"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="537" mass="58824" checksum="A1158829FC442CFA" modified="2025-10-08" version="1">MAPISVNIKHAGKTHAVQLDTDLPPAVFKEAVYNATGVPVDRMKVMVKGGILKDDSNWAKITPKPGQTLMVIGTAGELPKAPEKPIVFLEDMADEDLAGLERPVGLLNLGNTCYMNSTVQALRAIPELQVALGVPLRDLYANLSRTSDAVNPASFLNILRQVNPQFAERDRNRKGSMGIGGGYAQQDAEECYSQVLNSVRDVEVPDILIRPGAVNSGQRKRFVEQYMMGEMRRELSSPEAPDEPPTVSNEKIMKIECNINSQTNYMHSGIMSALTSVISKTSPTLGREAQYTQNSRITRLPSYLNVHMVRFAWKADVQKKAKIMRKVKFPTTYDAVELASPELKEKLLPASRRLQEIEKERAERRKVRKRTKIALAPSGLSIGTQGSTAVSGEDVPIAGTESATPAGGALEDEEVYRAREKKELESLIHPDLKADVGSSTTGLYELVAIITHKGAAADSGHYMAFVKKSVFHGPPPTLYTGSAADNATSTTNPENDEDWYKFDDDKVSVFPKEKLSTLDGGGEDSSAYVLLYRSKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWY7</accession>
    <name>A0ABQ8VWY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maintenance of telomere capping protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_755273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018814">
        <property type="entry name" value="DUF5427"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265:SF1">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10310">
        <property type="entry name" value="DUF5427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="439" mass="47479" checksum="371E4689A9E432A3" modified="2025-10-08" version="1">MSSSKSKTKQEEALQLLDDLDSFTPIESAVSSGSAAAPAPESETEVLAFLDEITQKSSEPTRPTTAHLERPASRTGAPSLRKSTERVRLGGSSLSTGTSTPSRAGTPPTNSRTTASSEPASEPAPATGVGGSWGWGSVWTTASAALQQARSVVDEQVKNLPSNEQAKKWSEGVKEYAKTHQLDKLGQDFKRVGLSTLTDILNVVAPPISEHEVIQIWLSHDMSGYDGIENIVYRAMTRVLEQVEGGDLIVNRGEESRPKDDAGNAARELNTVEGYEAAVKLSQANLDELIKIKDSALKAKKETLSSIQSPTSYSYVYLRVQPYLTSYSVPSTSALASTDGSAPAEQSKQQHLQFLLYLSDPDHNLIHSTITQSVPGVWLGIWDDYEWVEDLVAEVLRVGVEVIGQEYLVSRMGWGGLNVKQKLGDNEGESEGTVEKEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX52</accession>
    <name>A0ABQ8VX52_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_751057</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00617">
        <property type="entry name" value="COPPERFIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="8">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="131" mass="14454" checksum="0C6B1657339A44D3" modified="2025-10-08" version="1">MIYVHLLIPSKFSETCIKGHRSSGCKHTDRALYEIKKKGRPVTQCEQCRELRKTKQVHVKCICPKGEGSGQASNLKGILRLNKTLQKPAFPNGLPQASIAVQHLSEGSSDSEYGTVVSLSQHRSLLTLRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX62</accession>
    <name>A0ABQ8VX62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_862654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639:SF1">
        <property type="entry name" value="DUF262 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="379" mass="42994" checksum="5F794F327D12B967" modified="2025-10-08" version="1">MSIGIGPDKDSVTGQKYWYKEIEPTNDEPTKTKTKKQLLPETLRKMFANKHVVCTEYIGLTSLEERDIFSRVQQGKPLKNSEKLGATSTNRTIFIRSLLERYVTAETLCAIPWKTSRGVDNLCFSHAVYCMAKWSIDPEEVKDHRSLKVLGEWLAGSQEIADDVKSQVHEAYDIFVRLATSPKYSALFHKQKKVSPVEMIFIPLLIFVHGVLPSKELRYNLRKLCAHIASMRRSVREHFREVCSNLRVGKFLTNFIKNIEKKKATNNRKRNFEKEEAEDDQVIVATTSAHWNLSIPETPTMSSVNSNTAALSTESLSTRPALKKRKSTLDSATFGLNCTSPRQALNPSMRMTSSLKSRNPLSLPFWLSLHRSASGSRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX92</accession>
    <name>A0ABQ8VX92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33864" checksum="4DE553C705564948" modified="2025-10-08" version="1">MSQYASLRAQFFEGDIRTKSSPDEPTDPIAEMLSGNAQWAKAITESDPDFFPTTARAQYPHRQTSNERDGSWTEVQRRLGLSEKSIEKEIRRYLDLLLRSLYIITPTMHLRLYLWTTYLVIGLIYAVWAVPVPAPLGTTAIRKVPGPSFKKRVSMVYRFPLPFAKTLVPFDEHGKESLAAKAVVDMIMKQVAGELHLPMPPKGTGTGSAQLPEIIIDNARSSSLKGYTPSKIFEFEITNEDGTGKCRGGCTCFVRPALKKPGVYEVGITDIWADKYVIGRSLTMDPEALQALNTTFPFRWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXD9</accession>
    <name>A0ABQ8VXD9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DASH complex subunit DAD2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_479031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="13925" checksum="A5576BC5BBDD6A9D" modified="2025-10-08" version="1">MMRPSSISNRTSYGMGSGPPTTSQAALLKLNEKKKEFDAVAALERTSSAYLERISGLADDCDVMALAGEVHGQVSEQWPRMFHILNLFLASRESSEDQPNAASQEGEMLVRIPIEDAMESNDASTSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYZ5</accession>
    <name>A0ABQ8VYZ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase C terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_805028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052515">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013944">
        <property type="entry name" value="OxRdtase_put_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43249:SF1">
        <property type="entry name" value="D-GLUCOSIDE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43249">
        <property type="entry name" value="UDP-N-ACETYL-2-AMINO-2-DEOXY-D-GLUCURONATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08635">
        <property type="entry name" value="ox_reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidoreductase putative C-terminal" evidence="2">
        <location>
            <begin position="166"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="400" mass="45298" checksum="F3AEDB1B8AB5DF1D" modified="2025-10-08" version="1">MTHISGTDDFNVVFVGAGNIMFGSEEGPWNHSFRFEHKLGRRLKVVALIDPATERAKEVLRKKCDSFVLSAYENTRIYKNFDDFHKNLPKSLRPRAFVVGSPPMFRGTLQSGRDIEVQILKHYPGVALFIEKPITTGPVEEIEQGYKIAKQIEESKTICSIGYMLRYLKAVQMMKHIIDENNLTVMTTIARYACAYEAIAKPDWWDKSKSAGPVIEQGTHFCDLSRYFGGEVDYSSVVAHSLEWDENAGQLSAIKIDESKIPPENRIPRVTSATWKYDSGAVGTFTHVVALQGTNYSCELEVYADGYCLRLVDPYVQPVLYVRKPGDDHEQTYRFPDDDPFFSEVSNLIDIIEDIEEDPDAACILSNYEDAVKTYELTWAIRKASEKSRAAKLEASRKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZK3</accession>
    <name>A0ABQ8VZK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein transport protein SEC22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_812771</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15866">
        <property type="entry name" value="R-SNARE_SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044565">
        <property type="entry name" value="Sec22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45837">
        <property type="entry name" value="VESICLE-TRAFFICKING PROTEIN SEC22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="15">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="16">
        <location>
            <begin position="138"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4499975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="25237" checksum="0217F66AAB7F9AA4" modified="2025-10-08" version="1">MVRSTIIVRASDALPLAASVDDEQTEQALQEHKQQSKLIFRRITPNSEPRCSIESGQYTLHYLIADNVVFLTIADKSYPRKLAFSYLDELSKEFATTYGPKIETVRKPYAFLGFDTFMSKTARLYRDTRTASAANSSGLDKLNDELQDVTRIMTKNMEELLWRGDSLDRMSHLSTSLRSESEKYRKAARNINLQAMLRQYAPLGAVALILMIFIYWRFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W079</accession>
    <name>A0ABQ8W079_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_362441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="21564" checksum="41C6595103B4DE4B" modified="2025-10-08" version="1">MFNFGKAKLPANWPPLHHKCNRSKCTFPNYPQPAPGTYKCRGCEKGNYSVSPAQAKEVDAQNRKVFYIPGRSPPLNVRRQPQSWDLNQEFPTSVRVGGPKQTFHTDVHTIARKVVQAPTSRHGPHRAVMGDPSIRNAHAVYPSGLKTTTRQIYASSDHTLVSNKDPQSDRVGYIPVRAERRPERPYRVVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W094</accession>
    <name>A0ABQ8W094_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_196815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="256" mass="29334" checksum="168EC49DF274EE17" modified="2025-10-08" version="1">MLVAGRFAGQNYRSSIQYSIRPYRQRSSNSMLPKLLPAFFLLSTFAGTIASPLAARVFDGRYLSLLQEILSNRILLLLGWNVIMLRRISTQKISLGSQTVPEPGETWSVFVTGFTYFRAKPQPGEYRPWQGTGINISRIRCSWRTGLVIARVQFASNTEKAEVLEYLGKLKATSNLLYLIKVLREMAAMAQGKEKITGFEWKNQLEWQQQYWKMIEMFEDGLGGKVDGNEKKIYHDLLMKRQEKAKEMEAKKSGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0B4</accession>
    <name>A0ABQ8W0B4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_811060</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19526">
        <property type="entry name" value="RecA-like_PEX1_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015342">
        <property type="entry name" value="PEX1-N_C-lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09262">
        <property type="entry name" value="PEX-1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="346"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="628"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4500335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="943" mass="103416" checksum="248A4CB16310BEEA" modified="2025-10-08" version="1">MASASSLAQFNVSEPTEKGLETIEIDPQYSQSLGFAQGDIVEIGLLHDMAFAKSVATEPLTSDDWEIIEIHASHVESTLLSQVRVAKVGQEINVWVLGRTRVRLKIVSLAPQAKNDALLLSTNTEVSISPKLHANRRVHAKEPTVNRTADAAVLKSIPQPFQILRVLPNHVLSKPLTAYSGTEVLGYVSSSTLAQLLPASRSVAKQPTYHKVSVKRLESPVNPVSTLQTPETVPETKVLNPSEKTHNVENSDNAEYSYVGGRDELIGGHIVFPSLPAGIEHWDLIKIVADSSAGTLTISGDNNTETLTPHPETAEFLAGVDDILKQCVEFCVRKIAIHSTKLSVPGVSSLLLTGRAGVGKTSIVKTVAKALQQNPKTYTYTHYIDVVPYADKPIPVVKQLFRYWLETSIWHKPSILVLDNVHELLGIESEQSDSFRTRHITELFLSMFSSSARSASSNYRGIILLATAPSSAALHPLIGTAHVFEKVVNVTPPNKDARRDILSKIMHDRLVAANDLAQSSEAPINFTYLATQTEGYSATDLQDLVSRTVHQVTMRLTSENQRPIITMADFETARADFIPLSLRDIKLEKSEVSWADIGGLHETRRILRETLEWPTKYGPIFAQSPLRLRSGLLLFGYPGCGKTLLASAVAKECGLNFISIKGPEILNKYIGASEQTVRDIFERASSAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSLLCNMPDVGERKDILEAVSRKVSLAASVDLDEIAQATEGFSGADLQALIYNAHLEVVNAAIVSSPSGKGTLSQPNKRAIRYTTIGGHSKTIRSKAEESALQRKLQQIQVASQPIQEWPDDRVDAVAHKQQIMQDHIRHVLKTTKPSVSTEERQRLDKIYRTFMFDRGDVPSAPSDYAGVGNRSTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1I5</accession>
    <name>A0ABQ8W1I5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Nuf2 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_7307</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NUF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.60">
        <property type="entry name" value="Ncd80 complex, Nuf2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005549">
        <property type="entry name" value="Kinetochore_Nuf2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041112">
        <property type="entry name" value="Nuf2_DHR10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038275">
        <property type="entry name" value="Nuf2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03800">
        <property type="entry name" value="Nuf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18595">
        <property type="entry name" value="Nuf2_DHR10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="11" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Nuf2 N-terminal" evidence="13">
        <location>
            <begin position="6"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Nuf2 DHR10-like" evidence="14">
        <location>
            <begin position="262"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="292"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4501644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="445" mass="51048" checksum="9663C184AA638E3D" modified="2025-10-08" version="1">MGAKGTYSLMSIPDIINSLGDWGLTVEEDRLLRPTSEFVEFVFCACLAQVTGINREDLLQPAQDALSISSLEDKDNIYLSALTHNLLCYHLTRFANAARVDDFSSYDISKPTKERTLLLLSAFINFVKFTEQLCNPFVNELVNRSNALLVDRDQVSSKLAQTQKQIQELKAKRDKDEPICQELRAKNKELGDLVLQTKAAQQPIVQEAALLKEEKTRLMERKEHIQRELEAISDANKRIRGRIVQSPERVKRSISTMSVSRTEHKKMVAINETKARDLQAKINALVIIEQDLRTCIDQLQVVEKEIKSLQDMQKDLAELKDQLHDKKIERNELQLKQERVVKQLENAHAKLTLTQQRAADKKAANARILERLQGEYNDMAEQRQENDLQLAEIRKEAAEVEEKISEHLKVSEEELHGLLKEYWSLKCATNVYMETLATKLNMKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A700</accession>
    <name>A0A9W9A700_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Small GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_537057</name>
        <name evidence="7" type="ORF">C8R41DRAFT_852098</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000024">
        <property type="protein sequence ID" value="KAJ4474102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A700"/>
    <dbReference type="OrthoDB" id="6585768at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090068">
        <property type="term" value="P:positive regulation of cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04128">
        <property type="entry name" value="Spg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000330">
        <property type="entry name" value="Septum-promoting GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017231">
        <property type="entry name" value="Small_GTPase_Tem1/Spg1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037527">
        <property type="entry name" value="Small_GTPase_Tem1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="225" mass="24918" checksum="B5AC680B630CE07D" modified="2023-11-08" version="1">MSHSASSSISTPAASGSGSSQNLHPHLENNDEKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDQFATFPGDEQEEITKQAKRFARAMHASLIFCSTSASINVQKIFKIVLAKAFDLKCVIPEIEGVGEPVLIYVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9E0A6</accession>
    <name>A0A9W9E0A6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ubiquitin-60S ribosomal protein L40 fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8J55DRAFT_554457</name>
        <name evidence="12" type="ORF">C8R41DRAFT_786766</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000002">
        <property type="protein sequence ID" value="KAJ4494843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9E0A6"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000014">
        <property type="entry name" value="Ubiquitin-60S ribosomal L40 fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.50:FF:000001">
        <property type="entry name" value="ubiquitin-60S ribosomal protein L40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_eL40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="Ribosomal_eL40_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 11" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4494843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4500834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="128" mass="14624" checksum="4FC31DD2B88F1EEC" modified="2023-11-08" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKELASKYNCEKKICRKCYARLPPRATNCRKRSCGHTNQLRPKKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW78</accession>
    <name>A0ABQ8UW78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000156">
        <property type="protein sequence ID" value="KAJ4463627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="75" mass="7719" checksum="48BAD1FC7F8051B2" modified="2025-10-08" version="1">MVVNAYYSQCLPGSALAPPTSTSSTGTGTTTSSTPGSTGTTTPAATTPSLVTRFITSHNIMFARLIHENKSNVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWG9</accession>
    <name>A0ABQ8UWG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_927213</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF22">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4463903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="536" mass="59716" checksum="F6A8AE2688EB2B16" modified="2025-10-08" version="1">MSDHDIEKRSDDGRKEGVLSREGSEKEEINLTTFHEKRAGRLVVSPQEARIEFGEAVASKLKLSKDGTKVLWPQPTDSPYDPQNWSNRRKHLHLFIITLAAIVPDFDSGIGIASIFPLATQFNTTTGVINNMTSNWSIFLLGWGGIFAVILIRRYGRLPILFWSQIFALGFLIGCTFAPNLKTFTAMRCLTAVFATAPQVTGLYVVTDLFPFHLQARKLNIWTMGFIISPFLSPFAFGFLVARTTWRWAYGIGCIYGAIVCVLIILFMQETMYDRTISPIPEPAAQGGFRYRFESLVGISGYKMAKYRVSWQDAILSPFKVVWRPHLLIILIFEAMVFGFSIGINTTNAVFLGSPPPLGYGFSQFAIAGGYGTPIVAVLIGELIGRFNNDFIMNVSIRRNNGVFEAESRLWACYLAMPLYICGFVLLGASFQDHLSVGALVMGWGISELAVMINTVAVYAYCNDCFPKHQGEISALINLARTLGGFSVAYFQVPWALKHGALQVFGVEAAIVIGLFFLSVPFIQIKGRRLREKYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWY8</accession>
    <name>A0ABQ8UWY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_891735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000142">
        <property type="protein sequence ID" value="KAJ4464356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="190"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="322"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="488"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4464356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="543" mass="60498" checksum="A9933B03C27CE552" modified="2025-10-08" version="1">MSSFKNSRYGKRLRATYEEFENENSQPDRKRCRINLEPPTTISPSRRVRTLFKAVPNTRSLRVKHLKTRCSFEFGDRFVPCQENNIQISYNLGDEPRPCAPSASLDPVKDRANDLYKTVLRSELTSSPNTPRRVFAYHSSEKSLSESNSRLDDPTDKIYQLSPLQLQTWKLIAQARPRIRKVARTPYKSLDAPDISDDFHTNLLDWSPSGTLGVGLGFEIYLWRADTDEPTPLCTIPSEKDEYSALAWMQTSPIIALATYRGHLEVYDASTRQLVRRYRNAHGKKRIGTISWTSHVFSSGSGDLSINHWDFREPSAKPFKKSGGHKSEVCGVKWSTDGGVHASILASGGNDSKICIWDLRGSTRDPGLVAASNPAASSISSGGKQVTNGIPPLYEFKKHKAAVKGLAWNPHYSGILASGGGVRDRCIRIWNTTTGRMLNEVDTMSQVCNLIWSVTSHELVSTHGYANVTTPNQICVWKYPSMSRISCLNGHRARVQHVALNPNGDTIVTGSGDQSLHFWNIFPGKTSGVRGGDSVLNYGKLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX29</accession>
    <name>A0ABQ8UX29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_860041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="322" mass="34981" checksum="5B5406F8A59CBF61" modified="2025-10-08" version="1">MLPQLLASITSISNISAPLISSYLRRLCFHPINPNKLYLSRVFEGILNPCLETGRHYVNGTNGKVHSVRVPFHEHKEMEISDYFSALGYLLTHATSSASFTQAIHLLSCYAEWCRVSSSVLNINTPTVVQMLFDDPNSCKSASHTLAHYGYGNKLKFSLASSISAGKGEGREDVRAKRITALQSVWSHPLLYPSPVQRAHASAGIGYGRSPIEPSVELFGTPWGHCGESVSFPSMHKSITLGRPLGTLALNVKAMTCVIPGTNVVPVYAMPLLTSLADMVEILKISGALRPMCLNCLYLRNTAGGCIQDHAVKFSTFADDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZR6</accession>
    <name>A0ABQ8UZR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="47647" checksum="7AC2C8A99AD16D92" modified="2025-10-08" version="1">MTGSEHAFFTLPLELHTHIFTLACTPNSTKECTAGPSYYTAFYTGIALSLVCKYVRAASAPVRHRAVVIYGWHEMLAFERILSNSQTRSRVRYLTLVADELPQDPISLLSEASSATESSSALSPLSTSQFCYKTNLERKLLEVVARILRGVENDLYELEIGFQAIENIKDPLAYLSLTGPGPHSPLFFPCLDTMFYACPPSNAFPWGMSSKPTPVINTILTGSEPTTFIPVSPNLTCPRLKELTVVCNDSNSTLQSEILDDQFPEYIPEEGAEEDTDPREPSTTEETHNSVAASAELLDAEMTTNKFPSLAMLTLFASTPAQALAALDVEEAAWDVGSNFQIDICGLRRNITSTAGPENPLETAGDTRSSEEFHTVVLRPKARWNERWESLRDVARRQREAKVEEGKSDDYAKSASETELEVFVLKPGEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V126</accession>
    <name>A0ABQ8V126_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CPSF A subunit region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_782943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000143">
        <property type="protein sequence ID" value="KAJ4464270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="13"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="5">
        <location>
            <begin position="460"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="857"/>
            <end position="1176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4464270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1211" mass="133466" checksum="C6CC3983054DB15B" modified="2025-10-08" version="1">MHLYNLTLQPPTAITQAIVGNFSGVRQQEIITSHGTRLELLRPDPQTGKVATILSTDVFGSIRSLAAFRLTGGTKDYAIVGSDSGRIIILDYDPKTSSFVKLHQETFGKSGARRIVPGQYLAVDPKGRSVMISAMEKSKLVYILNRDAAANLTISSPLEAHKNGAIIHHIIGLDVGFENPTFAALEVDYTESDQDPTGEAFKNAEKMLTYYELDLGLNHVVRKWSEPTDRRANLLLQVPGGQLASSDRFDGPSGVLVCCEDHIIYRHMDAPQHRVPIPRRKHPLDNRDRGMLIVSAVMHKMKGAFFFLVQNEDGDLFKVTIEHEDEEVKSLKIKYFDTVPVASSLCILKSGFLFVASEFSNHYFYQFQKLGDDDEEPEFSSTSYRSFGMADPTAPLPNEYFRPRPLENLALADELESLDPILDSKVLNILPNSDTPQIFAACGRGSRSSLRTLRHGLEVEESVSSDLPGIPNAVWTTKKREDDAYDSYIILSFVNGTLVLSIGETIEEVQDTGFLSSARTLAVQQIGTDALLQVHPEGIRHVLANGHVTEWKSPSGKTIVNATTNKRQVVVALSSAELVYFELDLEGQLNEYQDRKAMGSTVLALSIAEVPEGRQRTPFLAVGCEDQTVRVISLDPESTLETISLQALTAPPSSICIAEMLDASINKSQPTLFVNIGLQNGVLLRTVLDPTNGQLTDTRTRFLGTRPVKLIRVQIQRNPAILALSSRSWLNYTHQNLMYFTPLIFESFDFAWSFSAELSPEGLIGITGSTLRIFQIPKLGTQLKQDSIPLSYTPRKFIAHGNYFYMVEGDHRVLGEDAGEKKLAELRQQGKKIDQEVIDLPVEVFGRPKAPAGTWGSAIRVIDPVKAETVAYIPLDSNEAAFSLAVVPFLVRGGELHLVVGTAADTTVSPRSCSSGFLRTYKFTDEGRGLELLHKTETDDVPLALLAFQGRLVAGVGKALRIYDIGKKKLLRKVENKTFASPIITLNTQGSRIIVGEMQESVSFVAYKAPENRLLVFADDSQSRWVSAVAMVDYNTVAIGDRFGNIIVNRLDTKESDQVDEDPTGAGILHEKGILMGAPHKTKMVAHFHVGDLITSIHKVAMVAGGREILLYTGLHGTVGILVPFVSKEDVDFISTLEQHLRTEQSSLVGRDQLSWRGYYTPVKAVVDGDLCETFARLPGSKQSAIAGELDRTVGEVLKKLEQLRVTTSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2J2</accession>
    <name>A0ABQ8V2J2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_781148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF58">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="30992" checksum="F70471A9C6F97119" modified="2025-10-08" version="1">MLLALVIKIYITVKSWHDKPWLHRNQWSNVKYLSSSLVLKFGRDNVAAEADTISFIRSNTSIPVPHVIASDRAFGKTYMLMRRVNGMPLQFAWRDLNAEQRTNVTEQLRSFVAQLRTLSPTLSRRHSVGAVCALNNAPLSDSRISSAPVGPFPNERAFNDHLIVVAEPYMDETTLPSIRARMFDDHRIYFTHGDLTPRNIFVQGGNVTAIIDWEESGWYPEHWEFIKALWCTLKDPEWLRAVRYIVADDFEREWMLDRELSDHMVGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2L3</accession>
    <name>A0ABQ8V2L3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_603474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="23730" checksum="7C19A305FB7DAA0F" modified="2025-10-08" version="1">MYPRPILKARLSSFTQRSPASASPSSSFHNPFPFYSGLHTPHVHFPPTPVIASTQPTHSSSTYDRTAITVSPNSCELPERGGRCYSPSYATHAPRVTVNSYFDPLAGKACDTASYDTGTPPLLIPDLSSSSSSESEDSDAYGSPLFSPPNIPFSYSTHTSNCSIPSTFSQEEFVHAFSFLPHPPSQVKDDVHRRPNSSRYDRGDSAFQEGSLDGCLGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3G7</accession>
    <name>A0ABQ8V3G7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-P-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_926155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000116">
        <property type="protein sequence ID" value="KAJ4466337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4466337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="312" mass="34077" checksum="8418FD7F03113ADF" modified="2025-10-08" version="1">MGNSGSYIAQSFPPSSEFMVGDIPDLSGWIIIVTGGNTGIGYEIIKAVLLKNAKVYMATRSSEKAAVAIARLKVETGGKEAIFLELDLASLSSVRNAANEFKQKESTLHVLFNNGGVMNTPTQLLTTDGYDLQFGTNVIGHYVLFKELLRPLLAGAQSSQDKKARIVNMSSSAQMFINTIHFDTIKDTPKRRKLGSAKLYMQSKLANIVFSNEIGRRYSSEGLVSISLNPGNIRTDLQRHTPSAFMLLFGWLFSPASLGALTPLYAGVSSASGDLNGKYLIPWARIGKMRPEASDLSVGEKLWKWLEDETKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3N6</accession>
    <name>A0ABQ8V3N6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_593333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047047532" evidence="1">
        <location>
            <begin position="21"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="163" mass="16997" checksum="2442978D41A2F6E8" modified="2025-10-08" version="1">MLIIKSAVLLLGSLLTNTFAAPLARQDASGSIVSPVSGTVINPGDAFDFSYFARGDYGITSLNYTVFLMTSPPTSLAPSANFATGHYFGRFAEPNYPAPTQLVMPDFALSPGGWGVGATMSNGTFYLVVLEEYVTGNPTVGALMSLAITEVIYNGTSSATSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3P0</accession>
    <name>A0ABQ8V3P0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4471019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021986">
        <property type="entry name" value="Spherulin4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040:SF9">
        <property type="entry name" value="4-LIKE CELL SURFACE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12138">
        <property type="entry name" value="Spherulin4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="42648" checksum="A0D4AE5F33FC75C2" modified="2025-10-08" version="1">MAPFFLYSSNLNQIAQLGHLQSRHKQLLKILMSLSVLMNGFPLLPRILVTAEVKVFTVINPSNSPGLAHSQPPANYQACIPSLVDAGAKQNTLHLLGYVDTANGQRNSVEVLMDIETYAGWDEGELFGETGMVALNPSAVPDSGYFTLSDLIVTVNKDYNIFNFSNLPLSPSTPIEKQIVILYNAPNNLDFSETIVDEISAIANIKACFITPSLKDTEYTSVPDSLFQLLGSLIGPDTSQLSYISSLSVSFISVSPQLYFFSLFPISGLFLSILVLSTPLLRLTIYVEALQYVLHPLEPPIRFPIPLHCSLSSPQLPTRIGYTSPPHRSGGYALRSTPLGPSIRSTQAPQLPLVRLPSPVSALSHTSSYGLGGYCVCLGPVWLCKLHEIIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3R7</accession>
    <name>A0ABQ8V3R7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_588574</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050460">
        <property type="entry name" value="Distal-less_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24327">
        <property type="entry name" value="HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4472650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="184" mass="20697" checksum="A97B5D4F6D886589" modified="2025-10-08" version="1">MKGHFSTRSNKPTRTIITAEQRALLSAAIEKVHYPSDDTIEGLSNDLRISPSQIRIWFCNRRQQMRRKEKGNTARSLQPAPPISPPLSLPLPQESLNVTPAHPQCSQQQQSNDPLNDITLPSISALFPEFIKKNSNETPYLISANPVRRCRRAETQISLPPITSLLQTIPPSPTQNYVQNFPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4D2</accession>
    <name>A0ABQ8V4D2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_775653</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="684"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="765"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="794"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4473552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="964" mass="106159" checksum="FE70DDA89D495743" modified="2025-10-08" version="1">MAQQSKKKRNDDETNAAPDGGQKPVQLQRRRVWRACECCRRKKIKCDGCEPTCSQCASSGSQCTWLQTKDRAALSRHYVQELEARLLHMESIFSQIAPVLEQFGINGGDAVNPSSVNGTVSLPPEIAAPASEILRSIAPRDTQQSASIPIKVEDDVSESLGQLALDEYGHMRWIGGSSTMSLIQSFKALTTSPLHRISPMEEDPLAPYPSANKLYFPASVFFGKVRALPGPEEVEYPERDLADKLVNTYFSRFHFLMPVVDKPSFLKQYHNIMDNQQNHSLVQSETAFISLIFAVFACAANLVQDDRLSMSGRTDEGGMGMVYYERSLILQYISHANTQTAHVQCFILLSSFLCSVNCLPQAWILVGQAVRTGQDLGLHRSPRRLVLSSIEIETRRKIWWGVYTLDRMLAVALGRPLGINDSDCDVEYPIDVDDDNLQEYFSGSLMNNNTTSLMTGIIALIKLYQIGGRVLRDVYAIENCKDNLEPERKAELQRMVEVLDNELTQWCDDLPPVFKSQPTTDEQVSMGAVLCSHYYSVLTTLHRNMLPVKRDQPVAAKSTAKAVSSARSCIRLAPSMKNVVPPSHHLAFFIQHLFSSAVILLLYAMHSTEPRAASAAMEEAKSTLSALESWEGQWPGARKCRELLLELTSTATEAITQAQTGQQKQTSESGIPISVAPAITSPALHERQRSLSGASPSSVAGRALKGAGRTRRTQSRESGTTSRRMAAVSPYRVDTTARARSTSRRRGFDEEIERVGSSMGPYFHSLSSPTNGSSHSSPASVNIPSPITNVPEGQESSPTLASAHTFNYGSPRLSSGQTPSPRYDSYDFGLSNNLNNYQGPAHPQWNGQQAGVDIYSAENMYGSSNGVYPSPLENYPVFETTGAHEMNNGMNRLSTTPPTSSFNASGLPFRGLEFIRNYSPGGYLAGDNFMGEPESLWQSYDPLSFNVNPDLPFTLGDPDVHGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4K5</accession>
    <name>A0ABQ8V4K5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_848695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046066654" evidence="1">
        <location>
            <begin position="23"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="18904" checksum="7A45B1C6E0703BC4" modified="2025-10-08" version="1">MRFEYNTTLFLIVVGLASTAYTLPFETSPSPNLTTRAVSLTPSQPPTDPNTGTGTGTITFLGTHSGVPLLPHESPKISTAYEDGHIPSDVYKRVRKAVREVVPGWGGGVLAFSNSFEGNGGGVGEMSGGGGGRNVAGARGRVVQYGVIEVSLEGIGRCHPGGCTFKIDRNGKVVQGSLVVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5D6</accession>
    <name>A0ABQ8V5D6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_970778</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="7">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4469611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="25170" checksum="E0AE319ED74CE979" modified="2025-10-08" version="1" fragment="single">KTSRSEYLQRCLFKHLEGIRVHYDNTLRSSDSSVYQFQYVGDSLDVTKQKHIRQFEFIARNEKSFVNKLRPKSILPFVAEDDAIVYMKSVIKRKPAKRHGIDPCLALYSPSRFLGSTSKAFADALKHYTKKNPDKSIKGDFEEMWSTRKTPLSAGTFRMLMHVKYMRSLVEPGEAVGLLASQGVGEPSTQMTLNTFHFAGDQNGTHGTQNRSLLVSLAFGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5I0</accession>
    <name>A0ABQ8V5I0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_718414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF24">
        <property type="entry name" value="RLPA-LIKE PROTEIN DOUBLE-PSI BETA-BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="95" mass="9706" checksum="395491C405760679" modified="2025-10-08" version="1" fragment="single">GGYATYFYQEGVAGACGTVHSDSDLIVAVDEDMYSSDLCGKTVVITNVASGATVTATVADECPGCSTSTSLDLSVAAFEALSDLSVGTFASKWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5I2</accession>
    <name>A0ABQ8V5I2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_547195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="138" mass="15397" checksum="C1B59CB5F18B4B26" modified="2025-10-08" version="1">MKEFQTIIAARASPKNVPTYSHRAEPLSPVVVSATPTPRHFSRPKRGRRLNDPPFVSGGLATCNNCHAVIDYHTWRELKYKIILEMDVRPAGDTILEHGLSEWPEALACWQAKCAQVGCSDMVQGSATIVERHAGRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5W2</accession>
    <name>A0ABQ8V5W2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="543" mass="56628" checksum="7FD54DB0387FE5D4" modified="2025-10-08" version="1">MSSKNSSNFREAVTPPWRLVSQNEPRSDSLLSREALLPDPTHVSPFLYATSPPSRRRKPRHDSECTMEVRSSSAPARAMFGPLTMGWSFQKQLQDLDKQSDRDDHDPRSPSGNLGSKKPPARSAYSTQIDIMSAVFSRIADFEFIKFERSFIPYANRNRETPSRTTTSDSQRINSMWRQKGPTGRKSGPPNAAAGPSTMHPPQRRTGKRNSTSPREDPDNVPGTGSPPTKKPRQSPVDPPPGPAYPQHAAQPGQPGSSMGPPGGPGPGPGPHQPTLGGMRPPMPGGGPPGGPMNVNGFGQPMGGMGGIGMNTMNGPALPHTINAMSPPMGGGMAGQQGMMTPQIQPTNPPGRPPPLDGPIQCHNSLANFHQRQLGGGGAGSPSDPGSTLGGGPNDGSAKDINMKIEGSPRGGLPPSSAGMAPTASGPANGPSSMPVPPGRPLSSQNPAPNSGPHPGSMLGNTPMPGMSGPMSGMPNGIGPGGMGSGMVVINCGINVMNGTGSDIPFFRSDFMNDIEVGGLDTFDPNLFRDPRGDSNFKRDFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5X1</accession>
    <name>A0ABQ8V5X1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_923694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="168"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4475099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="37806" checksum="A23AB3F6656C29DE" modified="2025-10-08" version="1">MTPLELHQAVFLLGPWLIGAFLDILLQGVLFGQFVHYAQWYHDDKLGLKLAVVGLAIITTLKSIQAFALVWIIFIRHFLDLPGAILLNYTTWWQSGNPLMVAAIGLYVQTYFCYRLYMIAKSPLPVIPIAILFVFAFAALSAATYFITISDTLGIGRWFAAHLASVFAGDLLLSLVTAYFLIRSKKNVLPQTVGLITALVRLTFQTAAPAAICALLNLVFSQIYDGNENITSTAFNMMLPKLYAVSMMWTLNARRTIGAAYGTSRPYTNASSADRTTRRARTGRNDPDVELGDFGGIQIHTQLDRHVDVWNSDDDVKQDGLRIGETSETSVTVPVTQKAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5X8</accession>
    <name>A0ABQ8V5X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_887450</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="433"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4476134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="718" mass="81188" checksum="CD645010A35AE7DB" modified="2025-10-08" version="1">MPRGVHRRKGGINTNRKGKFDPKDENQVKHTKIGKVWELYEERQPELAKIPFSARLNFERYLGLYDSLPFVWRMLKDIGSIRACWLYLGLYLAVQLALSLIPAVQLWYSGQLLTIVGTAIEQRTVDRQLLFRVASSRVACSIADLILQHMSKRISRPLNARIKQYYTVHMFSVLARLDVPTYDDPLVQRQLEQAFPSNSRQTVIWRTVVGVINMGSTAIMLLSQLSVLSNVLKNQQDGTLIAILSFSHSILSSSSDTQSLFTRVWAATTHNADFIKLSGLRKAVAEPAHRKEIVAGNMWEYMHSEYRRCINILGDDAAEFFDVYELFNQKRFPSFASIIRRPLQELPQIVFTLRAVQYPATIPLSLASLNLITSTANSFSHTLLRLFEQTGSISDNFATIQKMYEAINLANRITDGMVPYPENQRSLQMGMSIEFRNVSFKYPESKSYALRNVSFKIVKGQLCVILGQNGSGKSTVLKLIARLYDPLEGQILVDDQDIKTFKLADLRRAMAILFQDYTHFPLSIKENIALGDPGHSDDIDRIRQAATLGGASEFIEHLEDGYDTYLDRPVRDYYSGLPEGTMDLFGRAVSFGKIRGMGGMKSNESTTLSGGQMQRIALSRTFMRSSVSEPSVGLLLFDEPSASLDPTAEHDLFERLRLLRGQKTMIFSSHRFGNLTRNADMILYMHDSVIVEEGSHDALLKAGGEYARIWNLQAQAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V698</accession>
    <name>A0ABQ8V698_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="424" mass="47505" checksum="D442977B91A09221" modified="2025-10-08" version="1">MDHPMDDAPPTPTMAPPTPTTAPPTPTTNDPEMPPSNNSETSKMTSRGRRRLKPIRTSTMNDSEMSSAKRSNRRRKLSVSSSEDENSSSQVDDDICERPQKVTDFKVRVVERVVEREVVPAYVTQQIAEKDEQIQLLQQELEAKKTGKTKALREDDVSHSHSPQAAGSIEAERRRLRRDILDKRKTIESLTALNTQLQRDFAEVKQNLDALSKTAVAPDSVAAKDPEIESLSAKLDVAENEIKEKKLKARTRSQSIEETSNRKQDLEASIITKDSERAQLKEAVAVAEQAQAMEIIDLKQKLSDLDASIVAKDSHSQRLDCLIQTLKIERDKLDATVTMAQKEAEDESNARTVQVEQLKIRVKEFEEQIAVKESHELTLGNMIQSLEAENRKLEVTAALEKETTEPMPRAFTPPLGTPKICLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7I9</accession>
    <name>A0ABQ8V7I9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_512504</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VAM6/VPS39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019453">
        <property type="entry name" value="VPS39/TGFA1_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF49">
        <property type="entry name" value="VAM6_VPS39-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10367">
        <property type="entry name" value="zf-Vps39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="4">
        <location>
            <begin position="745"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="465"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="536"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="546"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4478570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115405" checksum="42BAE14EC3F026C7" modified="2025-10-08" version="1">MAPFLPPKVVMSGFKEKIDSLLVQGDRIYLGTATDELKKSLTKRSIEQLGFINDVNSVVTLSETTVTLFPLPSFSPPTILSAKAAFSFTIHSCTYLTESELQGKDEFTKPAPRPVLMTYLLVGCRRKVVIYSWKDGEAQALKEHPLPHSPRIISFMNDDLACFAYSATEYAVFSLSKKTVIEVTMPLPLSAPSSTMGALTGFSGYMTLGLGAKSKPGIVKLNEAESLIIKDNEGIIIGKDAKPSRSETIGWQAPPEEIAFIKPYIFSVLPPGSIPSTNTDPGQNSIPTSVVQIRSSISLLPIQTYLYPFREPSRPSSPAPAPQPSLLANATIRLMSPSLATNHSIFLVTTPTDRATATSEGSSIWQFEMKTWSEQIDELVLAGQYSDALKFLESIESKDLSDKDDRRVRIRALNAVSEFEAGQFDKAIDTFTELNINPAKVVALYPESISGRLSVPRDKWIELYGGPPKQKDVVESPTEGSEADSKGSETPKKSEHERSMTATDEMLDNLGLAGPGSIRGRLKGLGALMGAAAAVPTTQKDDDTASVKSQTSRPSKVNSNSDYHKSVESLVRSFLPDRRVKLGAALNAVGMTPADQAHEITSLSAMSVEDLYALPNAPFTQLTPEQLLRYAQIVDTALFKSYLVVRPILAGSLFRVPNWCEVEEVEGVLRARGMFRELKDLYHQKKMHRKALELLRQLGEKEEDLDERVYDSVQYLRKLGPGDLEQVFESARWVIEQNSDRGLEIFKSEDVDLPRNHVADYLEKISPLLCTNYLEYLIQERGEVSVDFHDRLVELYAKITLEARRKKEENLRQQTYDKLMTFISTTTHYRVDRLYGLLSSEDLCEARAILLGKLGRHDQALELYVYRLQDYLKAEEYCKQYYQAGTATSNVFLTLLRIYLRPTVKPNVDLLKPALELISRHSRRLDTTEALQLLPPLVTLNDVQTFLIEGLRIPIFDTDVIRQISKARDNQMARKLMSLQMKRVKVTDSRICPQCHKRIGSTIIAVHSPRGEVTHFSCREAFARKLNEFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7L9</accession>
    <name>A0ABQ8V7L9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_514470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="982" mass="111635" checksum="5D43D6806CAA77A0" modified="2025-10-08" version="1">MLRWLQSTVPTPGGYGGSAVRMHVAQKLYPKCVSPLSFPKHQSSILSGHSARFRAPSAVSGLPQNGAADVPQSSVLCDGAEYVSNERLRDLERLRLYLTSAPTKKLAPELLVSLYDSVRVSSQLKSFSATQLSTLISILGSSSLPPDAPRIRNNYVDGTSNTSGHWFHVLCVADDKKALGFLLNDGDHYWAMWAWLALSRSGDHVKALSNASKHYNQIWQKTKFPDILVPYLETLISTGSSEHLQTAVVDLCNILVVHTNLHGRSLKLIWDVFLSFSTALTPSMKTAILHALWSRSNMSHITVQRSNYMATHMFNPLTKRHERLPLDIAHLIASLGAPLFPFFLVSVPLSVQRWARRQTVAALSPSCSDEVRWTNFSLFALNQAARKGVGNHIPTLDPNFAGSDLNDWHIVLTLSILENVVNSYMASAQGSELCSLSGDLWERWMSLKADRPIFVSRAVVSSFLRLAARTQDTYILDQCYRYSIDHALWQTNRDHTAADRAQIEALIGFYFAAFIRCHGRRWADILHFLDVQKDLFVSGSHADFVIQRLSSLDIEIAFEFYEFCISHNVPVGVDITTMLATALAPVRVHEVFPMLERGLNHAQMEKVLLALLDTLRTQRYQYLNPASGRILGRALCKLLQSKAPVVRIKYPLRYSLLRLVASNCATDAIRIVELVNERAPSFLNARFLHRLLGIFLRHRQYTLAGRLYYVIKSRSIPAQDRFRRKLILGLMRVERMVTRLEFRGAIPCRTSSDRVLSIVRKYPNDIPSIKSAFSALVLSKRPVAAKRLFQDSLPYLDSPTKIWLGNMFLHRILRRFDKRNIQVVKKLLRAKNYLMMNFGFTGDRITFNILLKGMLRWKNVSSSKTRILFDDCIRMGYPVGSRWRRINNVPFGTQSLSSPITFGIPMPDPRISFQRHVRPLYKMFIKAFYLRKDVEAAKTVVGILKNEEAENLSRQQYRDYSRLEGLRRRRLTKGTTISDDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7N4</accession>
    <name>A0ABQ8V7N4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_922740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="6"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="306"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4478872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="450" mass="49955" checksum="8436A5289FF33C49" modified="2025-10-08" version="1">MGVIKLRVAICGGGIAGLAHACALARYPDISVNIYESTDKFSPFGAGIGVWPRAWNVLCALGLGEDMAKITSGSPTSSPVQSFSFRKSDQPSGFTFGNMFSRGPLLTFHRAQFQEVLVQHLPPSSRIHHSKRLKSYSQGRLGCPIRLLFEDGTYATCDVLVGADGIKSAVRNCLFQDQTEIAREIGRPADEQKTLTCKDHVSWAGSIAYRALIPVERLKEDCDQGLLVLPMTPTMYVGTDVHMVVYPVSKGKEVNLALFHFRPELQGMPFHGPWSKGVDESELFDIARFESWEPEVQRWLKYVRRPTKWAIHTVVDLPTFTSGRAVLIGDAAHSCSPHQGTGAGQAIEDAYFLAELLGDPRTTLNTVQQALKVYDKFRRPWTQDASAKAMANGRYLTLHYDGFDFVHADAAAVVQKLHELSDVMIDEWKWCWTTTVEDSLKAALSQLQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V881</accession>
    <name>A0ABQ8V881_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_843928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="416" mass="45355" checksum="59D3D4E99619F41D" modified="2025-10-08" version="1">MIPRLNRVKRTLEPTRAVPLLAQVVAGQRPTCSLFSHSYHEPLCARNTCSSVRQMSSSSADSTHINFDSTKGDPGLGLGLRHANPPDTHPNTSHLQYSTPPEHDEHNSKPELEELSDAEWELRTGRTIDILRLTLPTFFNTGLMTSWDPETGDAYPSPTLPSLPSLPHLPNLHLPHLPLPLHISPHPINKDAEKQTIGKRKERHERESIYSSRIRLAYTPPSPLPHPFPEKLTLDGKPLYLTSAVFVRHTLNTLYSDLRVTLVKVAVSVPRGKSSSELDSDSGTTPPLPPNPESDPEPGNSGSVEGFDDPHTKNSGYKREKSLYISLRVTGTSRVSGALGQWEVKSTYTFSPLNAQIIKHTVNGIEPAPERGVWEGLAKVLGLGNIGEGFNGGRQGEGALSGFGGHTRSKAGEGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9E2</accession>
    <name>A0ABQ8V9E2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_589426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056304">
        <property type="entry name" value="Lip-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24708">
        <property type="entry name" value="Lip_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Lipase-like C-terminal" evidence="6">
        <location>
            <begin position="54"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4472672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="466" mass="52547" checksum="8B90EEA0E88BC70A" modified="2025-10-08" version="1">MRNTSLSSCGQSVSNKYHGPVNNVGRHFASSSYPLQPMCDSKESGSSVQCQCIPLVIVEGFLGRTGSRIWGDFERHLNQECYQCKRRVIFAPVGPVSSLHDRACELYYSLVGGTVDYGEEHSIAHGHSRHGRTHSQGLYPQWSLENPLHLLGHSMGGPTIVKLQYLMKQGHFGSRAHPDWIRSINTISSPFRGTQIVYTLGERVDAAPRVRPLSPGSLLSKAVHAISYLSPILPTLLDLHTESRRMSYHDISILCLLKQLWKSDWAESQDAAPFDVTFESADKREANLEGQPYPRTFYRSCATYLTEKCEEDRNLHTVHFKLLSFPLISPLSLLARAVGSFDFSTIRPVPSFLEERGLSPIDTEQDLFATDFQKTLPEEYWANDGVVPLFSQWHPASCSSTRCQHGETKSPAPGIWYVEQWDNTSHSSLVPLWVASDCQKQYWLKLGRWLRAIESQNEYNIVTSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9T7</accession>
    <name>A0ABQ8V9T7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_869515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4477574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="28872" checksum="B6C88D9DF6C0197E" modified="2025-10-08" version="1">MDDFNAVGRYGSALATAAYFRNENTVKYLLENGANINEQGVVYGNALQATICDGNMDEDMKLNEDMINFLLENGADIETQSGEYRNALQAAAYHGNENILNKVLEKGVNLQHFWGNRAAVECLLEQEANVNAQEAEFGRTLGAVAYRNNKDMVKYHPERGADTNIQGGRFGKVLQTVAFWGHGDMGGGYSSALQVAAFNGYIDIDACYVSNGKDTDSQGHRNDDNVLNGALCGGNKWVVRLPSDNGAEINTWVVNLDMLSKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9W5</accession>
    <name>A0ABQ8V9W5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase A4 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_885514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13426">
        <property type="entry name" value="Peptidase_G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536:SF1">
        <property type="entry name" value="ASPERGILLOPEPSIN, PUTAITVE (AFU_ORTHOLOGUE AFUA_7G01200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00977">
        <property type="entry name" value="SCYTLDPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045317932" evidence="2">
        <location>
            <begin position="20"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4483116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="29713" checksum="15DCBBD38809E920" modified="2025-10-08" version="1">MKFLTFSLISVLFVSRGFAWPSRLANREASRRLRGSRPLSSSPHAVVNSTSNGTDSQSDPKSYAVTSSGTTLYDEYSTNWAGVVIESPPTGQNFTTVSGTFIVPKPTGSNGSASAWVGIDGDTASQSILQAGVDFTISGGKVSYDSWYEWYPNYAYDFSNFAISAGNTITITIHSTSSKAGVVTLLNKSTGKSVSQSLTAPSSSTALKGQNAEWIVEDYEQNGSLVPFANFGTVTFTNASASTLNKTLAPNTGIKINIVQSKKLLTSTSFTSNSVTVKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA87</accession>
    <name>A0ABQ8VA87_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_921964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4483137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="19911" checksum="489736F7CA02A9EE" modified="2025-10-08" version="1">MEGSAKFHIVLVSSIHQLIKAIKAIIGSDPQEDLYQGAHPSQGRSRAAGPLTHIDDDNSHRNFSYFDIYTTNNFDDDTMKFLTLAGFFLLLVAGTMTAVDAATEAEQACGFARKIGSPCTIKLDGQHSIPGTCQKKAGLKLFRHRTCIPNNMAGSTSSSTAAGAPPPASATSSPDTGSTSTGAGAGDGTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAK8</accession>
    <name>A0ABQ8VAK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eisosome component PIL1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_769840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028245">
        <property type="entry name" value="PIL1/LSP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962:SF1">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13805">
        <property type="entry name" value="Pil1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="555" mass="58628" checksum="A262A64D0447A89F" modified="2025-10-08" version="1">MPVPGFISSFADKAQSAIAEHIPGSHKPNSDPSAQSTNTAAQGSYGGVGHKNPTLEVIQHQLRTLGQQYGSGATPVQKIITTAKGVAIDLDSLARDQKAQSKELYTWGQGEEADLKDVSDRLAYLNFVSGSLASSLAVKLDAARSPLKLLRDAENALAPRRNIRASLHQQLTRLEHDNQKGMEKKIAELKDQIRKAESDDLPQEKEIELLKRKGVRESEQLKWEAIREYGEKLVLLSQAAYPVITALPTLPPSPEAPYTGAQATGAARASLQRALDNYKTGHINLPPQSAGSDLSRSDTRSFGESHASELSTISSETTQSNIPVTPPLSAVKTLPAAAAVSFSKPSADSTGPISSPSKQLPPPINPSALNLSPAPLPPSLNNLPSAISSSTSSMPITSPDSMKPISLPTISDTPTIAETGVPVLASESGPGPASGSLRDVKAASPTAGPRSGGLPSGDAPPTSFGAMGTSATGNDNKWESAEEEKKRLAAEYSQAHSGGSAPAPHYESAEEEKRRVEHEEREKLLRSGGHGPTESGEGRSSKKEDDDELPPYQDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAN6</accession>
    <name>A0ABQ8VAN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046615430" evidence="1">
        <location>
            <begin position="30"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="27358" checksum="7CD0BE58AC6F90EF" modified="2025-10-08" version="1">MAQATTLLLIMLSLSSSPSFLTTFFGANALPIDPSATNSSSTESLGSRMFTPENAKQANFLLGYTYVNTEIGTDYNTATQFTAAHHFEPGPLGSVGKYLSPRPAQIHELIPGATMECIATAKKDLVMKYGPIFVDAEALKNQQTLEKFLTEHKFSPRSSILIAHSPDTERKGELMIFLPGIFISTSVYNPAHPRPELNYLSTYVYCRPVQMMAHQPFRAVAAWEELQPRLWPKGLTTLSTLKYPAAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBM7</accession>
    <name>A0ABQ8VBM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_903772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="690"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="770" mass="83116" checksum="B5572BB599197AAD" modified="2025-10-08" version="1">MPLIVPILRMFMLFLNVWDTFKTLKPPPYKIRNGKAEPPTVRSVTQRKRDLKGCLAVWIVWCCFSTYERLVEPIISLFIPFYNELKSLVILFLIFTRARGAEPIFLHLLRPMLRPYTKSIDSSLELFRLIGDLLFAIISFPLRPVAALLPSYFGSRSPGDDIPPPYSEGPAAGDQYTPPSDFQQSSVQVSSFHPADPAADMEWRQYPNLPSAYPPTPLVTSSRLPVQGHVGYDASSAAGPHTIWIPPVVDEDEEDDGENQQGFRRSLLPPRVPLHPGLGNYDGLSDESDRGAENHQIIADFQSNGRPSGETSSAEETDDMEMDDDERNHRHSSDGDAGTDSEEDSFNMTLQTPRVPLSLQPSSATMSRSTIRLRASARSVFADLERETEGRRHLSGSVLLPPLDTTSRLGQGSSPSSIDSGSLSISSGDDSAFMSLPNPHSVVPSLIPISGNKNDDNMSDSSLGSAPGAGPVTTTMRSISPTGRGRKRSHSRSFPPEHSQRYTRSNASKFAGSTLQRLSSTESSSSSRAPSPSNDADVHEAVADTTLKDIRVFVDVEPISSSSASPVETQLGDVKSNNPTGENADEVRPAEGSVAGPRKRRKVVSLSSGPGHGSPPTSESEPTSRSHTGLIPKPSDAFLSDRRKKGFLSTRTRRQLSGASTSASEGTDGPSSSDNVRSTRPTSNSKGKGRSVAPSSTRVSSVPTRRHFDVSHKLAGASTSIRMTRSTVGLAPTAGTGTEASNETLNVLGIGLGANDHPLRFARARAKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBT0</accession>
    <name>A0ABQ8VBT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">WH1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_897235</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00132">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01205">
        <property type="entry name" value="EVH1_WASP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033927">
        <property type="entry name" value="WASPfam_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WH1" evidence="8">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="7">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="WH2" evidence="9">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="238"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="322"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4476291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="50665" checksum="87A75DAC3F471FBD" modified="2025-10-08" version="1">MPSQSILSADDKAKVKSVIPVSPATNKIYSATFARIYYAYPDPNKWAYAGLQGGCYTESQLTNDVTIFHRRSNLTLDFSFNLVDLTGTRGIIWSHEFYQGLEAEYNTDRPWFHSFPGDECMIGFVFVDESEAKSFEKNVREKSGKKSKGAKSKKSKSPTVKSSGKIDKSLISAPTQFKHIAHMGYDADKGFTSRNVDPSWTTIVGNLEEKGIDKETIEKEIKIIRDYYKIHPEALAEAEKKEQKKKLATTKPPPPPSRGGAPPPPPPPRGGGSRNSAPPPPPPPPSTAHAPSSAPPPPPARPSTGHHVPPPPPARPASSHTPAPPTRPPPPSSGPPPPPPPPPPAGGSAAPPPPPPPPPPPSGARTGAPPPPPPPPPPPGASGVPPPPPSLGLPAPQPGRGDLLASIQGKGIHSLKKTEGPPASGSLSSASPRGGTPAVEESAGSSSGGGGGATDLTSALASALLARNAKMGEDSDEEEEDDEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBY5</accession>
    <name>A0ABQ8VBY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Delta-12 fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_896407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="89"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="403" mass="46869" checksum="F632EF3EFAF82E44" modified="2025-10-08" version="1">MLSSAFADSPEYITRKDTPFMPSKITWNELHSSLPKHIFRRSTVKGMSYVVRDVTLAIVLYRLAWFLESPATVFFEPSSFLRLVKYVLWLFYFNAQGILFTSWWCLAHEASHGTLSSFALVNDTVGFVLHTFLLVPYFSWKSSHLSHHASTASVERDENYVPRTRSSFALPPEDRANVADYREAFEETPMCTTFRIVAMQVFGLIFYLLFNRKGSPRHPPGTNHFSPYSSLFKPRALGRLAFMVYLLYQWTKQVGFGHFFRSYCVPYLLTNYWIVMLTYLQHTDPTVPYYRRSQWTFVRGALASVDRPFLGWIGRVFFHNVSHNHISHHLFSSIPFYNQPLATACIKKVLRKEYNYDSTNSFRALYRSFTECEFIEDGSDIVFYKNRSGHANRVLASIPSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBZ8</accession>
    <name>A0ABQ8VBZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7770 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056672">
        <property type="entry name" value="DUF7770"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24968">
        <property type="entry name" value="DUF7770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7770" evidence="1">
        <location>
            <begin position="49"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="22961" checksum="C3B715178E4BEE06" modified="2025-10-08" version="1">MQYPSRVTLGEVLSSNSRYTYTTLQNLGVPAPQDGTMVYAIAVHAVRSSASVQQQQHTFQVAHFRVFLILVPPPPELTPHESVELNNYAHNGLITSTEVAYHPYIYSQRQLTFLRVSVVNATTVVTVGQVLDCIFNENGRQRYQLDTTTGSGCRYWCQTVIRDMVVKGWLSEDAPRKTEEIAAAIQTHNPDVTVSEVGNPKGGVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCT1</accession>
    <name>A0ABQ8VCT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_410579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4487481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="351" mass="38139" checksum="BB800ADEFA8121A9" modified="2025-10-08" version="1">MTKILMTGVTGYIGGTILTRFAQRSDFETFDIRAIVRSSEKAEKLKSLFKNVTPILGSHSDIPLISQAASEVDVVIAMADCDDVDAATGTLQGLRKRFEETGKKSIFINTSGTGVLSDNAAGMYPTDIIWDDANPDQIATLKPTQPHRPVDLKIVGADAEGYVKTYIILPATIWGISKGPLFTSGISNKKSVQIPALIRASLDRGHAGMVGLGKNIWPNVEIHELGDLYNHLFDAVVVSSSLPSTPGHGREGYYFGANEEHTLYQVGKSISDVMLKMHKSNGGEPTTFTQEEINKYFNGSSYLGSNSRCRPNRSKALGWAPKKTTQDMLDSIYPETELVIEIGAPAVSEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCU5</accession>
    <name>A0ABQ8VCU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_411590</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20908">
        <property type="entry name" value="SUF4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215:SF0">
        <property type="entry name" value="BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215">
        <property type="entry name" value="ZINC FINGER PROTEIN 207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4487496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="226" mass="23692" checksum="0F7E25D94109C29A" modified="2025-10-08" version="1">MKKHQKAKHFKCNMCPRRLNTAGGLAVHIQQVHKLEPENLPRIENALPGRDGYEVEIFGMEGIPAPDVADYKRRKEIELGLAAGSISQPPAKRPKTENRPLSEDELKAALEAHRALMGGANDNAPPAASDQSAGGVYGAPPQAYVAPPAPSGAMPGPPPPGMMPPGPPSFFPPLPGMVPGQPPFPPFPGMPGFPPGPPPPGFPMPPGFLPPPGMMPPARFSVTSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD37</accession>
    <name>A0ABQ8VD37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CNH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_920722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF1">
        <property type="entry name" value="RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="5">
        <location>
            <begin position="1118"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1368"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="1605"/>
            <end position="1903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="426"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="758"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="929"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1004"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1293"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1453"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1503"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1976"/>
            <end position="2026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="929"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1004"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1293"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1472"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1503"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1976"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2001"/>
            <end position="2026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2026" mass="222126" checksum="30AB0E014AB9BE8A" modified="2025-10-08" version="1">MENKRPLSPEVPDEDLQQLYDQVWAGFGSEDTQSIESASSYTPSTASVLSPRDGVRRQDTSEQDREDIGRIYSVYAADNLPDVVYNYGSPSSATNGSNIYQHQRDTDNYYGYISSPISPVSTAAATYARSARSASIRSNGRERSGSGSARRLPLPPTPASGWNAPTQMTTAKEYQRQGHVSSMSTSSISSVASSRKLPATPASAPVVTLGGRDLDRLGVGLPTSPRPSKSPSPTRGRGGVDSGLSLAADYLQPEANLQPRRNRSRSPYQTNRSMQVVSGRSANTSPALVAAPLPPTKSPRSYFDEKSRKDPGLSMNRWNSTSSSIVNGVNAQGLRIPPPPPLLSFQPPSQLRQPQYSMPEPDLYADPNAGPSSIVRRPTDMLRELSDGANFDRYHPEERHDQLGVDADEASYDWDEDYELQQQRFAADAPRSYQSYSSSQSQPQGSSSRRNRKPKNPRDWTYEYSEGNDNEYSSDEFINYSLLSHLAVQLRDKVPRGVHVKASIPYEGAFTGKDIVDTVQSLIRKHLLLNHSLSLTNSTPYPASFSSSSSSPSVDRRAALHVARSLQCQLLFYEVDGGGRELCDGVEEVYMFSEDDISSSPSGSGFGFGTMSPRMTSGHSTVLPLPTAVVTMLTRCYVPTCVDDKPCYASDCPKRGLSIQRMLSPSSKIAPVVINITDTSSYPSLEEERKPWRETVPEEVFSRIPEGEVKRQVAIHDLITKETDYLADLIVLETQFMLPLSEWVVSISGSQNLENGLVATTSSHSPPPTPSGSTAAFVSPPRMRKSSSSFSSSSSTSSPLLAFSPALQTLLPLLHALITAQTRLLDHLRVRARESQYGIIEGIGDLYLERAASSEWRAGWGGGWVQGRGFVSTADRAKEGWTGGRGYDEWVGVWATCGLGGLGIFSPAISTTTDENGNEDWKKIIAEQEMQRQQKQRESNPTAAEDESTGEVGTETGGIKEPRGYLLPDIDLKKFTELLALPAAHLKSYPSLLSTILAESSRSADPVSSLSSPSSSTDTAANSTSPAALKTNKKKAGKEKEENENPDASYLREAIRAMRALWGYGKVKTFQLSMNVCASGGDDNKGSMGVMGEAAIKWEWFNLVSEEERKEIGKTEVKRQAIIFELIKGEMGYVKDLENVEHMYITPLVNSSTSNTPIIPAVRLSQFLSSVFNNIQSLHFHHLTLLQALFRIQYDEHPTIRSVSAPILDAALNWREAYMEYIPNYPIAAYTIDSEMRTNPAFKDFVQRCTRHPDAHRLDMKNFINRPIPRLLRYELLLKGILEETPVGPIAASNRQGGSLTSSRGANAVHEDHSSIPQVLDVIRRLGKDTEPGVVNAKSKVELWKYNEGLVFKQGEWIDMDLLAESRSLIHSGKLLRQTDGLEWSGWTELYVLLFDNYMVLTKPKEREDVTKYHVNRRPIPLDLLTIDSLTEPPVQRGTGPGLLRGLRSQGTIGQGLEASSPNELLASSEGSTPVETPSSEMSPSTSSRLLYPITLHHLGRHSVSPTTSSLIPPLPAGPSSSRTAQQAKPPPNIILYTESATARAEWGAKLQEALGIRRVVQESNKVFEIETLSSETFVTPVGSDALGVGNAGVLGIGYSPDTVTGKVTCSVPFNTADGRGLVAVGCAEGVWIGFRHDPKSMRRVLHLKLVAQCAMLEDYGIFLVLADKSLFAYHIEALVPSSFQSASTSQVPQKLNGNKDVHFFTVGTLHGRTLVIYMKKKGLDSIFRVLEPVSEKIKERAKPPSGFGSRLFVRSLKSEWFKIYRDFFLPSESYDVIFLKARIAILCSKGFEIMDLNEHVSIPSSPRYANEHRSTTASKSAEDEFLLCYNEFGVYVDKHGDPNRPSGTIEWEGTAERVAVHAPYVLLFDSRFIEIRHLETGRLAQIIPGNDIRCIWDGRGVSPLTPMSPSAQNLSFPVLDRSDEPLNQDALVHAVMNAPDVVGGGSRGRFVVQQVFELLPTVPLFLPDQAPDGSSVVGSYSNSGSGSGSGIGAPGLRLSVGQSSNVTPPLPYSPQQLRNSPSWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDX6</accession>
    <name>A0ABQ8VDX6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_842575</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049940">
        <property type="entry name" value="GluQ/Sye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311:SF2">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="An anticodon-binding domain of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="2"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class I anticodon-binding" evidence="12">
        <location>
            <begin position="386"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4480307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="532" mass="59853" checksum="6025EE6747143008" modified="2025-10-08" version="1">MVLLRFAPSPTGPLHLGGLRMALYNYLYARKFGGKWILRIEDTDTTRSVPGSVEGIRKALSWAGLDYDYGPEKEGPHGPYFQSERRDLYRLYANKLIDKGQAYRCFCSADELADVKTRLARSGSNNTYDKRCLHLSDEEVARKVKAGEKFVVRINDGIIPTRPPTHDIVYGYVRDAHLSLATDPVLLKSDLFPTYHLASVVDDHEMGITHVLRGEEWLPSLPLHLDLYTHLNLTPPQFAHIPILLNPDRTKMSKRSGDVQVVDYMHRGWEPQAILNWLALAGWGAKHEAAAPITDGSETDSSLSSRPSSPHRLEDAPDSTHLMTIDEMISDFDLSALTHRSSVLDGTKLEYINKHHLMRTWSTPEGLDKLANRVHGHVKDAFKSSPYTTVDNIKNAITLLEGRLTNIYDIPLHAPYLFVDPDLATAEAQSMIRKVSADQRIQILDVFITLIQTNGWFTFQAASHESIMESLHHEREKLDVHLKVFMSVLRHALTGMKDGPGIIDIVRALGHERTIARLNAAKDLKDVKESAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE50</accession>
    <name>A0ABQ8VE50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_766485</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="495"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="646"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="685"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4491053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="772" mass="86303" checksum="EDE24A39EBD47597" modified="2025-10-08" version="1">MTKDPSKDEKTSIKAVPTEEPYSGNDEKINLSYVDSDTFVGDVYEDLRVIDLGDDGKERPIVTANDWSLRLISLEDDPTLPVWTLRLWFLSIGLSCFGAVLSEIFAFRPQTVYVSQLFLQTAAFILGKIMEELLPGPLNPRFPTQNNAFWRFINPGRFNIKEHVGIVIMSAAATHGALAINIFAADDLFYNVTMNPAIAIFTLLGSQLLGYGLGGMMRGFLVYPTSMVFPNLIPTIQMFDVLHRGHDNQLQKKRVKFFWTLFIIIFFWQWIPEYFAPLLTGLSVFCLARKNSAWVTRIFGGAAGNEGLGLFSLCFDWNYVGSGGSAYGALFQPIQTQLSLYTGVLICIISFCAVYANNVWNARNFPFLSQLLFFENGTEYDQTLILNDDFTLNEDKLAVVGLPWYTATQTVSKIGASLSFGATITHIIVWHGKELWGALLAARVCILKSISLFAQLLSGRLVYKEVPFWWYTAMFVASMAISIATNYTGDSELPWWAFFISVGFATFFLPIISALYAILCFVPGTEDVARMLGAALVPGRPRANMYFTLYAYNSTEQGRSMTRDLKMGQYTKLPPRVTFTMQCLGAVIGALLNYLIMKIVIASNREILLSVQGTNVWSGAAIQSFNSISWGALAKQLYSPSGRYGIVPISILIGLAVPIPFWLLHRKWPKARFDSIITPMITVEIGYLAGGINSSVFNTFLLCIFSQFFIRKYHPRWFRKYNFLLSAALDGGTEVMVFVYSFAVGGAGGRVVDFPNWALNPVGNPDYCKRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEG0</accession>
    <name>A0ABQ8VEG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_836370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45181">
        <property type="entry name" value="HEAT SHOCK PROTEIN DNAJ WITH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45181:SF4">
        <property type="entry name" value="HEAT SHOCK PROTEIN DNAJ WITH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4488630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="45200" checksum="E13C1E1F5F347348" modified="2025-10-08" version="1">MFAPTRSSIPNVISMENTFQQIPYTRRPPNNSAAIFPGRSTLTLLKSSECQSNPVHPQNWDIGTMSNMAIVPGSRWVMKIRYDGHFDIAGNSVASESPGAFSRHTFFCWNPSDVGKENVYRLANTFMGKLTADNIIIFIKACIFYPFPPHSPCIPQVIHLPVEIAPFHSQLQKFFSVFPSPFSYKIDNAEHTCEQNTQLRLIFRNGMERANRLKNDGNAAYHSKDGLKAADAFHEAGNCVKDLLEQNLDKSEREMARRFLAICYANRANVWLLPGSLMDLRRCVEDAIKAEDSDPSYSKSYIRQARGYQGLGEFDKAMDIIARALSREDLMYDVDLVKSLLVLQTDGKGLPQTREEMGEWKRKILAGDVASAKRMKSVPTNGAWYRKVEGHCTNICRERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEG1</accession>
    <name>A0ABQ8VEG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="23149" checksum="7BC45387B4C40344" modified="2025-10-08" version="1">MTTKGKKTTTGFKKQEEYELSRETIQNLITSQALKTGIQVPVDSAGWLDVVRKILTTAGEVVMNVPILLELYKGRNEHTSDECAAANPAPKSKPQTLAIQTHFQSSQIPEPTKEISKAVLPTSHLQAFDRSTVLTNSSPSKPAVNNDLEQPPINGISCTPIKPIAAQDKVTPISPLAQYNPFNSISSLFNKRQSKAGSNAESMPESYDQQAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF76</accession>
    <name>A0ABQ8VF76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIN domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09870">
        <property type="entry name" value="PIN_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF75">
        <property type="entry name" value="ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG-I" evidence="2">
        <location>
            <begin position="121"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="531" mass="58914" checksum="0DF8D397E56ACBAE" modified="2025-10-08" version="1">MGVKGLWPLIHPAASRLKLKDLNFEFGFIRNHHKSRTLNIGVNASLLLDTFHAANRGASQHSLHLSDTTLTQLQYFLCQLSEAGINCVFFFDGPECSAIKRGRHVINREPDYHKHAKALIECFGYYSHAARGDAEAELAHLNNQGIIDAVLTKDSDVFSFGAQRVLVPEFQKSGDFIVDVYDVDSIQNDLQLSRAGIVLIALLLQNDFDSGVLGIGPRTALGLAQCGFGDRFLAVYNQFLAISSELSDSDIFQDLVNDIAHEIEFNTHLKLGSCSPTRAQIFRDSNFPSSRSLTALKAFLMPAVNVSPAHNWPPRIPNVVRISAFCREHFNWPTQLALKKFHDDLWPAVIIWMLYSKFLAYNPRNSEILVPQLQGSLDFNNQGKPYVPTLSTISQNQGSPKLNGKQPNDDISVTFTMDFFIQLTGLAASSSSSRTTRRMNVPVALISVAQRRTHAVKGLEGLLVSSTFNDSSSYQFGSNGIRNNSSDAYSSPSLKRKQNSVRKETRLAHLKLNTGTKNLGVIELTDSDNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG62</accession>
    <name>A0ABQ8VG62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_839049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10206">
        <property type="entry name" value="ASKHA_NBD_Arp8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="683" mass="75912" checksum="4E175EFE5322C772" modified="2025-10-08" version="1">MPRGIPNAKRDDTGIKYTTFHVPLSTNPKHLGTTYLKSESQTIWFRNSQRRSKEETTQESRRGSQVLVIHLGSRFSRIGRASDVTPVTVPTVVARRCKTPVTPPTFIEGIARPRAGKKNLRPSEKSLDQNEYEVSATSDDPFEEKIAAITTSLRDRMRFYKFRVTPNAANIASTFNGPFRPEIIAEHNDPYRVDWINGPTDEEVLVGDKALRLADPQSSNFIVRWPIYGSTFNTRDYTSSQVVLSDIETLLRYTLHDKFAIEPRDYAILSVVLIIPDFYDRYYVRDLVSLLLVSMGFKQLCAQQESLAATYGAGISTACVVDIGAKTTSIACVDEGLVVADSRMSLNIGGDDITEFLYVLLERISFPYKDINLAISYDWNVMEDLKARLCTLMEVDVALNLYDFVVRKPGSPAEKYGLRAYDEIILAPMVIFEPRVIEFDNKRLGLQDLNPSVTEEILEHTSDHVTSAMVISTQHLLPGPSDTPALQYTDQKADKTSSDAGPTLGTSSNIIVEGSTDVPMEVIDIELEDNKSSGPHQSSPSKSARRTSSEPVQPFLGSFGVDVCFEASKLPLDVAIFNSARASGGDEKIRKYLQAVLVIGGTARISGMGHALESRLQAIATPLVQNMERVQIIPPPKDVDHRVLAWKGGAVLGKMEGAAELWMTQQDWDILGMRGLKERCFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHY0</accession>
    <name>A0ABQ8VHY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_895651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="14"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="36830" checksum="6FA1DB2FBE9C5326" modified="2025-10-08" version="1">MSQQKALMLEKAKGPLVVSAAQPILKPGPGQLSVKVIAVALNPVDWKIQAWDVLLKEYPAILGLDIAGDVEEIGEGVEGFSRGDKVFCQGFFGNEMAGFQQYTLIPADIVGKIPSNIDYAQAATIPGAFTTAAISLFKAQPEGAGLNPTFDLDIKFAGRSAVIVGGSTSVGQYVIQLFKLLGYSTIIAYASAHHTDYLKSIGATHVIERGEVPVGSLAEAAKKIANAPIEIAYNAVGDKDSQAACIDAIIEGGQVPDVNPEVVENEDSKNGKRVFTIFATPHHPPHREFCRILWKTLPNLVQKGVIVPNRVEKLPNGLAGIDQGLQKLKANKVSGVKLVAFPQETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI71</accession>
    <name>A0ABQ8VI71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-hexosaminidase</fullName>
            <ecNumber evidence="7">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_895257</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06562">
        <property type="entry name" value="GH20_HexA_HexB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF26">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001093">
        <property type="entry name" value="B-hxosamndse_ab_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286462" description="Beta-hexosaminidase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="10">
        <location>
            <begin position="21"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="9">
        <location>
            <begin position="178"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4495348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="60125" checksum="8329415E372E35EC" modified="2025-10-08" version="1">MPLFITAIVLALSAIPCCLSIWPIPRSLDSGNQILKLSGLFDISINFTNPPQDLLDAVTRTKYSIQNDQLERLIVGRGLSDSTAFGSAKTLRTLVLALEQSASTAQPIATEAVVALDTRDEGYSLSVPLDGSAGVVSANTTLGLLHGLSTFEQLWYTYDGTIYTNYAPLTIVNDSPAYAYRGFMLDTARNFFSVSDIKRTLDAMYLVKINTFHWHITDSQSWPIQVVQFPELAQAGAYSANQSYTSSDIQDVVTYAGERGIDVQVEIDTPGHTAIIGASHPEYVACYLSDWITFAGEPPAGQLRLADAKVANFTAAVLAAVAETLPSTIFSTGGDELDTACYAADGPTQMMLNESGKTLFEALDIFTSTTHGALHALGKTAVVWEEMVLEYNTTTLRNDTIVMVWISSDDAAAVVQKGYRIVHAPSNYFYLDCGAGEWIGNDPTGNSWCDPFKTWQESYTFNPLANISSAQVSLVLGGEQLLWTEQSGPENLDSIVWPRAASSAEVFWTVGNISEALPRLHDVRYRMVQRGIKAIRLQPEWCALRPQVCDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIG3</accession>
    <name>A0ABQ8VIG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="438" mass="48532" checksum="BCD41A6FD4A934E4" modified="2025-10-08" version="1">MHTGETADFFPWPESNASDGILDFKMPEVKEESHTEFSSLLSPPSSPFIAASTLTSKSVRQRVAKSESPRIRPYPELSREDTIGMSGTSGSGFDNWSNRSGSNERRSSDGGPHYQSAMYNSSQLSRSSSASSTSFNEAVGLGISPSGTVARFVTMSPQQSDVQLASMSWHQSQMSINETSDLSLYPGVAGDIPYHYSSDADHGGFPSGTPSSSTPIYSYDDTTTPIGDATTYNDSTSHSLASVECLHQKIAELEERHHHDQEHIRLLQAQLASFSSRNADYSYSPPASAFFKASWAARTTARTKYLCSLNRAGNALCAWHDSRRERRAYPPRNAPKDTLNCGCTYEEALFEESLSRHRVGSYLPGESVRMDPALRNPLLQLLKHRYGYQDGDFERDPFTGDWVSEDGHEEGHEHWERLLASGVNPRRARGEQHRNTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIG6</accession>
    <name>A0ABQ8VIG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF30">
        <property type="entry name" value="PHOSPHORYLASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="389" mass="45626" checksum="EEAD3E3E6711C04F" modified="2025-10-08" version="1">MSTARERLALEFPDESPYNEELWDFEIFWRDHYDWLKDRGYLLRPRYRPGWVASWIGTTKEAPRCEDNLVQPLFPLNLDAIRVADGKPVMLRRADPPSISNELEIGRLLSSKESLSDHRNHCVPIYESIELPNANEEGRRCIVVMPLLVSWEEVEFETVGEVVDFCGQVFEGLQFMHKMNVAHNDAKANNIMMDWSPLYPTPPHVLRTSMRMDWKGPSKPRNRTLCPIKYHFIDWDLSKQYDTRGVTLRMPGYGGDQSVPEFRRKEPCNPFAVDVYCLGNVIRQKFIEGDPILYDPPRRNVEFLRELVFNMTHDDPKKRPTMDEVVARFDKIRKGLSWWKLRSRVSDKTIPFIFHLLYSPLHWSIQLTYILRRIPAVPDYTTCGEHSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIU7</accession>
    <name>A0ABQ8VIU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_762553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="35"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="148"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="311" mass="35314" checksum="12253F7D8F7D0B5C" modified="2025-10-08" version="1">MPKDNQWLFPVEALYHYPSREPLHKTLYDLSRGVEFLFRLGTSLKLPSPALFTAATWFHRFYLRYSLRDFHRQDVAAACIFLATKTEECGRKLRDVAKVYHSKLTSIDITEIPLECKEVDQYQTAILVTEEYLLQAICFDFTVESPHAELVDLFVASPDDRVVQDYAWTFAHDSFRTPLCILYPPRVIAAACFVLAQYMAEGPNSLPLDARISFSAPSASLPTPPSHKAPSPDASRLAIEFFTLSEKDVQSVADALTLLLEFYSAQDLSMHPYLHDIATVLPPKTRTSRDPIYKSFKQFVPDVVVSARIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJA7</accession>
    <name>A0ABQ8VJA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_761854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045592929" evidence="1">
        <location>
            <begin position="24"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="59"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="356" mass="39377" checksum="C9B38619846F8746" modified="2025-10-08" version="1">MFSLVPAVLYCVLSAFVTLPAASQTNGTSPLDPSFYKDVNVTRGFVYHYYSSPPEAGKPVLLFLHGFPSSSYDWRNQIGFFQDQGYGLIVPDMLGYGGTAKPVDPHLYASSLITGDMVDLLDAEDVDEAIVIGHDWGAKVVARLANYFPERFSAFGFLSVGYFSPSILEISYAELNNITKQAIGYEIYGYWDFFSTNGTDQIIEDNLDSFFDITFTANKVLWITDFAPQGGLQAWLESNSTTAAGDFITPEDRAISIDTMRSEGMRAALCWYEVMTSTIESDDNQGIPQENLTIKKPVFLGAALEDYVAIAALEINSIIQASENATTIQQYDSGHWVMLEAKDQVNSDLLAWIESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJK7</accession>
    <name>A0ABQ8VJK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045475334" evidence="1">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="185" mass="20159" checksum="6B97FE5213479DCC" modified="2025-10-08" version="1">MKVSNIVLGATSLFLVKATPTIITKREQIVCPGQVTVSEIFIGANSNVKLAQVYCPENTVPTLTPRQDNGSTNCFTPSGGGPDPNDCTVIADAMRFYSQNVTLPLHVEDDTFLIGTGTNNTVVLTYSTCETFYVNQDPVEQSYCYSDWASIVDYIAPNCQSTQNAHGGNCVADDQQWFIQVQTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJR6</accession>
    <name>A0ABQ8VJR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_376082</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23024">
        <property type="entry name" value="zf-HIT_ZNHIT2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046379765" description="HIT-type domain-containing protein" evidence="5">
        <location>
            <begin position="24"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="HIT-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="265" mass="28767" checksum="8DD08AFCEE1148D6" modified="2025-10-08" version="1">MSFARLTLSRSFLLLSMFRHSRPGRKNQRKCNVCNEGEGKYSCSACFLPYCSVACYKKHKELDENCINCMQGGSAQSNSTSLPAATEVLSSTTTSDLSSDISPAGSTMQVRNVGVDPSVLDATSLKPLSSLKWPYIADEEPIYPDPLERNDPKPLRTRHYEAIATSQEVRKALLVPSVVSGQPDQPNMTLRALLVSIDKLSGVGRERAIQCALGADDGRINDELRQGNSSSLEPSEGVLALRTLAEAIEGALRGETNGTLSVDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJZ5</accession>
    <name>A0ABQ8VJZ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_825689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="27137" checksum="E656866A98780BCC" modified="2025-10-08" version="1">MMVDSWLERSGSLPLHILIAQWHLNSFLAPQNLLNRLVPFCNRLQSLCLALPLQCLPSFLDRQPAFPVLNKIDLTLLQNASKSEFSDVIPNFPQCRRFTTFLNALQLRTVKLNLSCSAYGNSSFLAQTVFMIPLPLNQLHSLHLELRDPGDYYSLSDARSYFDLLRNCQHTVVECRFSVWNSGRKRTRRGLSSISLSRLLLPSVSITVIMAGMILLTRSPGISSPLTRDPPPRYRHWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKL2</accession>
    <name>A0ABQ8VKL2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_310052</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038:SF16">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="11">
        <location>
            <begin position="22"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4494271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="101" mass="10603" checksum="AC3964F637B2DCEC" modified="2025-10-08" version="1">MSFLSGARPAGPTGGVNTDKIDMAITELDTITDFFNRMVASCHAKCITPRYTDGELNKGEMVCIDRCVSKYNEVQKKVGEKIQSRGAAAGGAGPGATGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLR0</accession>
    <name>A0ABQ8VLR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_827677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="33301" checksum="1274A226549CFE76" modified="2025-10-08" version="1">MTTPQMPVAIFVGGTSGIGRGMAEAYAHHLNGIAHIIIIGRDQAAANEMISSFPKPTEPNTEPSSSAGPIFLHEFVSSDFSLISNVHKTAKSLLNRLQRIDYLVLTPGVSLFARRKETKEGLDEKMALSYYSRWTFIHDLLPLLRKSEIRSGAKVYSVLSAGRGDLESVDTDDLDLKKKHTIQRCRLAVSTYNDLMMQKLAKQDPQIGFSHAFPGLVRSPMLTSSMWYYLFYPFLTFFAQTPEAVGKIQISTCMASPPGFNRYGEMGESLKYMPADELIVERLWNHTLQVTESLREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMC5</accession>
    <name>A0ABQ8VMC5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4246 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_209865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="32950" checksum="2FC306DC0B78BB1A" modified="2025-10-08" version="1">MEGMPHERIIASFIYYYSTDSAIQDHGLSFRKFRDVNDDFPAVEDSDYTHEDFHLSFLVNTNVSGDGQNSDDDEDPEYDSEHHYPSDWETVNESSHIPVTTTSLPFFINLGTVPTTNFDLDGKGERKGNSTGRILSFPNWLQHKVKLVKNSESSRNSNINDETVATRKIFCFFLVDDSGSQSSLDYIRQPGFSTRGVSHMNVLTTSEIPMQERKTNVPTTRAFLRIVSLKLTGQEISPELIEIICDYVLEGTLTREEAEWHRLTLMSERKVNAKGRYARRNTYSLCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VML4</accession>
    <name>A0ABQ8VML4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase family 32 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_824969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="641"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="649"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4496842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="714" mass="81051" checksum="CC8C323BF400399C" modified="2025-10-08" version="1">MSYDRLPTTIPMYNDGSHDGNDTEHFASTSASASASASPNPITQHRHRKRSSTASYGQGGYGYSSYSTYPSSRRRGPSLSPVRTNGSNWNYNIPIPPIPIPVPRFVRQVGSLLLRTPVYYIRKSIRALYRGHPVTTNTNSRRINLRRVKNPSPSTLPKIIYTLLLIAFVTLLYLLLRIYEPHIELAFYSRKFAREEILPVKPLAGCFNRPSRRYNVTERLFGARATDVHAGLEMRFGLDCYEFAGTVRSQIPAISHPAHRSRTQFHTYWRSDLALFGPRQEYMLKSFFATQNLATSKLVLWSNGDMRGNPILREYLRRYGAVEGDQGDTDGSERGSFDVRVADIALLARGTELDPEYHAHENEAESERNIFPSAHRLLLSDSKAWLDGDLIRLLLLWNFGGVWVDMDFLLTRDLEPLLEHEFVTQWDCYDKKYTPLNGALMRFHIHSPYLCEAVHIMATDSPPRPHSTDWGSTLYLKLYRRLLRGGVRPFKVLPWCFTDGRSCRLDNRLPDPFKEDQKAGISWWEEQSGGSSVRSSWWMPWSKMKPGTNGVSVVGNPTTKKQQLSGIDKDVAPSMGLGMGTEIVYTGNPPALARALSQIFGIHLHNQWEKNFPEKGWVERLLLQRYEAVLEAERIPALGTVTGHGGGNLEHRLQGLQGRDVDDLAREPVELDIGSKSRGQEQEQEQERDADMTKRDIDEQGDGDRTAMVRTADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN00</accession>
    <name>A0ABQ8VN00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_917152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="424" mass="44530" checksum="668A3D81E19409B0" modified="2025-10-08" version="1">MLPSLEFTRRDNASFTRSIQPSFSFVPFSATSSTPSSTPFTSPSLNPNSGASTGFATTSSTSTDEVSTSMTSPSTSTFNEVVTSISATQIFPSTTSSLATSIATSTLATFTTSPSFTPSITFTSSISSTSSHSSTSSLSSTSSAYITSISSITSISVYTTLQSFQGSESASSPSGAVSVPATTTNIAITDGTSTSAVFATASISGQTAVASSSSSSSVGFWSNKAAVAGTFTAVAVVALATLAGVILCIRKRRRDLYSRDRSISEKFASMDFADTRPYSTPSEPASHDLSHEPMDAYANRDPAFYLTHDPFVANAHNMPYAGSASLPEITYSYAQDVNNQYPYYGNEANNVVPPAVGTRSTPALPTQDPRNPFDSVDITPLRNAAIPQELERISSNPFEEPAFRASYQQSVDSFYGASIDGRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNW2</accession>
    <name>A0ABQ8VNW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_757660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavoredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798:SF5">
        <property type="entry name" value="FLAVIN REDUCTASE LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798">
        <property type="entry name" value="FLAVOPROTEIN OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="5">
        <location>
            <begin position="83"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="286" mass="31812" checksum="909FC2246BF8B63F" modified="2025-10-08" version="1">MIFIVKPPPSLVSSFIRIESRRWNSTKPFDLHKSFQMTTSPLPAWKVGNGAFTGLSPEHENSPKNTWNLDDMSTKDSYKLLTSAIIPRPVAFISTIAEDGTPNLAPFRHISHNPPLLGVSFSLSPRRPKDTRENILATKEFTVNIISEHFIEAANATAVEAPADIDEWTVSGLTMEPSTQVKPACVKESLFSMECQLHFSHDISDLKTSDITNTLVLGLIKQVHVTESVLAENGLTLDPAKLRPVARLGGNTYARLTDAFDVPRPAWKTVRDTVHELTERKSKKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPC8</accession>
    <name>A0ABQ8VPC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Protein transporter SEC24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_917480</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01479">
        <property type="entry name" value="Sec24-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041742">
        <property type="entry name" value="Sec24-like_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="27"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4497442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="938" mass="103399" checksum="AF0168CDFAB32677" modified="2025-10-08" version="1">MASPAQQLPPGWAAEWEQTHQRYLFIETATGHTQWEPPTEPSAQMQQPAMDSPPIGAAPAHHSKRRQYAAGQTQAYYGSAEEPSMLQPMSQPPQQAGMEPQLFTPGLAAPSFAMQQQGQTQPPYYDPNQAQQQPDYINSQQQQPAYGQPNPNALADQFSQMGLGGQRSFSLQTANLLTSPPDPRELSLPPPEIRLPPNATVTPSQFANADPSYQRSTLNAFPNTSSLLSKSKLPLALVISPYRTVSENEPQVPLVTDTVIARCRRCRTYINPFVQFIDGGNRWRCCMCNLSNEVPQMFDWDQTRNQPGDRWSRAELSHGTVEYVAPTEYMVRPPQPAVYVFLIDVSHTAVQSGMVATATRTILENLDRIPDEDDRTKIAIVCFDVSLYFFSLPPGQSEPTMLVVSDVDDVFLPKPTDLLLNLAEARSGGGLESLLTRINDMFKENSIIGSALGPALQAGFKLMVPIGGKIIALSSSLPSIGVGALKNREDPKILGTSKESGLLQAASPFYKTFAIECSRAQVSVDMFLFSSAYQDVASLSCLPHYTSGQTYYYPAFNAARTEDALKFAHEFGEVLAMPIMLEVIMRVRASRGLRMSSFHGNFFVRSTDLLAMPTVATNQGYAIEIQIEETINTPFVVLQTAVLHTTCYGERRIRVVTSAYPVTSNLSEVFASVDQIALAVLLANKAVERTLSHKLEDARDAVFNKLVEILQTYKSSMTAAGAGASAQLAIGENMKMLPVLILGLLKNVGIRQSAQIPPDIRAYSQALLTSLPAQLLIPYIYPSFYSLHNMPPEAGTVGPDGVIMPPPLPLTSERLERHGLFLIEDGQTIFLWVGRDAVPQLIMDVFNLPSYDVLRGGKTTLPVLENSFSQRVNAIVQKTREMRRGVYYPHLYIVKEDGEPPLRLWALSALVQDRADVLPSYQQFISSLKEKVNGNGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPW8</accession>
    <name>A0ABQ8VPW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">S13-like H2TH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_916975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22738" checksum="29BB9E0BECCFBCEE" modified="2025-10-08" version="1">MVHILGINLPDNQLARFALTSIYGVGPHLSHRLCARFQIHDKCRVKDLTPLQTTSLASFLQSPKTALPLPQYPLAPVNFVARPPSKSIQELQAEFNAARTAQKQKREEKLLQLGQSPAEDAKGKTTTTRGRKALEKKSRDPLTELRIESELRREIRENIAHQRMIGSYVGRRHAMHLPVRGQRTQTNAKTARKLNNLDRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPY3</accession>
    <name>A0ABQ8VPY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_916301</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="338"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="622" mass="70600" checksum="03625CAF8712A531" modified="2025-10-08" version="1">MHEFMDTKIDTMQRVVVLLIICQSMTAVLKKLRFGFMHFLNNRAHIAVMFSFNSSRKIKYGIRNRFYPIFARKSLTLSLDTTKGSVFPWHRLLRFIYPSELVVQEILPLPWAFEIDKSLGWEFLHEFTIFLQNYITIGLQISILLAMVARQTMVLDLGAFCCTMVPIFMISIPTNGLGGIGYSFWTNNPAYHRVAAMHQIIFDIGYRKSVLKDGAINFIIQEYERSMKELGFLSIDAEMLCYGIPIPWYWQVLEMVVEIPLIIFLFTYPIVEKGSSLSWFMTGLFVQYASSKLRQNIQKVRTAQKPLHEVLGLAEQFYKGLSFEKPLLEGARAYPDKTRSFPLARQSSLRSRSAVRDVSFDVLPGQFVLLVGQNGSGKTSLLHLISRLFDPSTGAILIDGVPIQDFDLQSLRQSMVVLLQTEEIYPISIRDNLSISLSESDKELCNSKPESFDRAAKMGGSYDFINDLKEKYETVLNPVSLFTTSSDVFGNGTVPLAVVEEMRRNAPCMAPIPLSGGEKQRLIASRAFMKLNNHSDVRLLIVDEATSALDAIAERNILGKFREHGVHKTTIFVTHQFRYLAHEADLILCMHEGRLVQKGTHSQLISDTEGEYAKLYNAQVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ32</accession>
    <name>A0ABQ8VQ32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_820788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="71" mass="7838" checksum="7B15D08485ABE813" modified="2025-10-08" version="1">MGGGLRVGEIQTLRLKIPSNVLIKAHRPLLPYRILCNDLPRQDICIGCTIKSIDALKILDDLASGILQILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ91</accession>
    <name>A0ABQ8VQ91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_979108</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00175">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="29"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="187"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="361"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="531"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="5">
        <location>
            <begin position="739"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="921" mass="101301" checksum="DCCE1BA648AC60CD" modified="2025-10-08" version="1">MSMKAIVKSDYLVRHYYVTVLDNMQPIGVISGDSLVLRGRPGPQGQPPKERVLHLADVSAPRMGSSSREDELWAFESREFLRSLAVGKEISFTSTHSLPPNEDVPRDLGSAEIGGLDLASEILKNGWGKIKESKRDPTEEDLRKRELENEAKAAGLGVWNPHGPKARATHYTMPTDSQAFLSEYKGKPLDAIVEQVRDGSTLRVRLLLPEGDHQLVNIALAGVRAARASTKQGEPSEPWGEEAKFFTESRLLQRPVRVQLLSLPTSTATPFQPNGSGSAPATASLFIGTVLHPAGNVAEFLVAAGLARVVDWHAGMLAAGGGMERLRSAEKSAKEKRLCLYASAAQPSTSKSSTVANGQTRSFEATVIRIWSGDQISVVEKGSSKEHRLQLSSTRGPKLSDPKQGFYAQEAREFLRKKLIGKPVKCTIDFVRPKEGEYDERECATVRFGNQNVNVAVQLIEKGLASVVRHKRDDEDRSPDYDSLMAAEAAAAAESRGIHSGKDVPPLKQSLNISESSTRATPFLNGFKRLGRVPAVVEYVAAGSRFKLLLPKDNQTLTLVLGGIRAPRTARNPSEKSEPFGPEAFEFATKKYMQRDAEFEVESVDKSGGFIGSLYLNKTENAAVVLVKEGLASVHSYSADSLSWSKQLYDAESEAKSAKRNLWQDYDESAEKAAEVAPEVEAGPMKSKYIDIIISDVRTTNFGFSVQILNTEGIASLEKLMRDFSLHHQGAVTVPAGFTPKSGDLVSAKFSDGAWYRAKIRRASPIKKEAEVTFIDYGNQDSVAFKDIRPLASQFRSLPGQAREARLSFIKLVDPESEYYAEAIDRFRQLCEGRKLVANIDAQEGPLLHLRLIDPQNPQSATDPYECLNAELLRDGVATIDRKCNYLSAYPQLLRKLKDSVLEAKKDRAGMFEFGDVEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQK0</accession>
    <name>A0ABQ8VQK0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_893931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB_mito-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006667">
        <property type="entry name" value="PRK09212.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008854">
        <property type="entry name" value="PRK11892.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624:SF96">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="329" mass="35677" checksum="5C49CF5EEF688E3C" modified="2025-10-08" version="1">MTVRDALNAAMEEEMIRDEKVYIMGEEVARYNGAYKVTKGLLDKFGEKRVVDTPITEMGFAGIAVGSALAGLRPICEFMTFNFAMQAIDQIVNSAGKTYYMSGGNVPCPVVFRGPNGAAAGVGAQHSQDYASWYGQVPGLKVVSPWSAEDCKGLLKSAIRDPNPVVFLENEMLYGVSFPMSAEAMSDNFLLPFGKAKVEREGSDVTIVAHSKMVTHSLEAAELLAKEGIKAEVINLRSIRPLDIDTIKSSVKKTNRLLIVEGGFPAFGVGSEICAQIVESEAFDYLDAPVERITGADVPTPYAANLEELAFPDTNLIVKVAKRSLYRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQW5</accession>
    <name>A0ABQ8VQW5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_758347</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048535">
        <property type="entry name" value="RRN6_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048536">
        <property type="entry name" value="Rrn6_K-rich"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10214">
        <property type="entry name" value="Rrn6_beta-prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20639">
        <property type="entry name" value="Rrn6_K-rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRN6 beta-propeller" evidence="11">
        <location>
            <begin position="152"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="RRN6 K-rich C-terminal" evidence="12">
        <location>
            <begin position="755"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="919"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1016"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1129"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4497997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1234" mass="137687" checksum="FDBA4E2B24A17D28" modified="2025-10-08" version="1">MESWPEDKQSQVQHKFGRGGKGKGKALPFGTSYLELGRLEAVTLIENKTNLEWNSPLRSRGGPKLTLGDSVEVFGPTRPPPVHIPSTSIVHRAEQGANFLRTYFPDIEIAAELVREELSADAQVTRDLEQYDPFSRNVLELLYMPNLPDTPKFLAFPMGVTGSDLSIYSLSGLQDNNNMSFQASSKTVKSFTTPVLQLVSSQILTNSPNMFLAVRTMGSTTLLRSAYTPDSPQAVFTELSNITRDDTGERPSVDVKFHSKQSNVLLVNEEGRLYKSNIENGQSSVTTEIISRIIQSHGYVSRRTAYHGIKNYDSADKYWRLAVARDNEDSCLLSSSKVVQELDFRTDGVALNLLDIDTTTGEKLTWIEDSDDSYLIPLVSTDRILWLDRRCAGKPLLGIKHGRNYDRTLALRTVIIRGIHHSLMTSRKNKLITVYDVSRSTEQLLHADNAPYSFSVNTRESRSSGDAYVNMGDQYKMFRISERGRLTCVDLKQSGNEITSSFAATQFFPSETNDIPAMRPHLGAVGAREFSQTNLRPAYEQLFTSIVSIDTQEEENSEAVYDLLEQLPSFWQQDTPIEQVLTTYDILFRTGDEPEHTSRADFLTETVFNSARGYRILLQDRLPVQSFLDGASWYSDIAPIMNHFDESTVGNIRSIAERFRSFDLSSSPDHPIQASRRQNKAREQLALDLTLSKDIFSTQRFTQFPRTPAGDCTEASGPPAPVHFHYLQPMPRRDHYSREEQQEDNVNFPFGVGLLLEDWDVGVDPDKYIYNNTYDVKAELNLETTPKIRVQPVQSQTTLLPSSLSQSQMPPSIAILPVNQPLALPLRVSGVQSQMTEPTEVESQVLMTSTQVLPGPFGGRPTAGKKKPAKKRMGGIDRPLNALFFFRTSDPVYSTAFNDFLGRTVLSFTLSCSTREFFVAGNKAVVTALSASCISTFAGYPLDSLKSRLQTTKTPISVPRLALTVYRDEGISGFYRGLAIPLLTISFVRAASFTIYNSTKDYFKKREWLVRDSIVDVSIIGGISGAMSGALISVGSTPFELVKVRRQLEYTIASSKGIHLSRAPGTFEAVRDIFRTSGIAGLYTGFRLHFTRDTTGTMLYFLEYDGMRYLLGRQRSGEQGPIPAGIPIPVSLAPFVCGSFAGVTSWALIYPLDVVKTKVQQRALAGERYRGPFETFHRLIRGPDPDKPKPFLAGVARIYRGLGVSAVRSITTHGLLWTFFDLVANYIDSLPKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR74</accession>
    <name>A0ABQ8VR74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_730688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="1">
        <location>
            <begin position="13"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="19814" checksum="F9C6517F63925C2A" modified="2025-10-08" version="1" fragment="single">MYFCRDCYGSLRRSTMPRLALNNYLYRGELSDLLKDVTWVEEMACCIYRTTAHVTRIYGSSNPSDSFQLHGNVCAHPLNICATAKQLPWTPTDLNDLITIIFVGKKKLTPEDLMKFKPFFVRRSVIRLLLFTFCKHNRLYKDLYILDNSCLNLYPENDLLPGLAERIVYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS16</accession>
    <name>A0ABQ8VS16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_711720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="76"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="361" mass="40854" checksum="4C66DABCEE84CE22" modified="2025-10-08" version="1" fragment="single">GVLSTTQLIEDSPSDMLNYEPHELICTTQPAVPIDATREHYPDGWTECLITGLMKQTVLQTPSFCQPLSQPDHASYRVGTASTPNGPTSKPLPGLYATKKLEMGDLILSERPVLIVPAMMRVGEIFSELLSQLDNHDQATVVSNQWQETLETVFGRLSKEDQEEFWKLRDIRQRNGKKSIDGIVKANGFAILGLADPGLEDNDGAYSGVCLVLSQLNHSCRPNVERYWDMPSFSMQLRAMRKISNDEELTVSYINQLEPYAVRQKNLKLFDIVCTCQSCKKPKIGDRRRTQFLKGKLTTDDFLHWIKDASLSDDHIIKRALVQISLLEDDGLEDSPYYSDNLMMIMLCYVALGDDEKAMRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS34</accession>
    <name>A0ABQ8VS34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_816093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="278" mass="29137" checksum="81B00B90E1C571FA" modified="2025-10-08" version="1">MSVMPLTVSSSWTIDLTWASPFFISVADSAGNYWSYGPLHSGEGSSSCLASSSGGSISAGTIAGASVGALVVGLLVGALGAFCLFRRRKSGKTSYAGLDTSSPSGSPNVTPFDTGYRTAPLGGRLLDSTALNRSPSGTEYQVEPFVLPEHNTGPLSPSSEGRQDDPNSQSRSVYVVHHDGGRAPVTVYHEDGTEVVELPPRYIDGGSNTASRRSDARSRSDTRSEAGLSNSDTQMSTELAAQGSSRQTSDGQIPSFLQSQRNPQATPKKNGFRLQPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS36</accession>
    <name>A0ABQ8VS36_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_816306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6533" evidence="1">
        <location>
            <begin position="26"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="74" mass="8462" checksum="76EF4AA7B5F281F8" modified="2025-10-08" version="1">MTSNPSGTAVSGDILQIFNDYSAVKYTNAAFLTILIYDYTLTINLEMISVWSLPWKLPKFLFIINRYIVPPMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSF1</accession>
    <name>A0ABQ8VSF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_58848</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="170"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="343" mass="37408" checksum="B290D13F82C4EC4E" modified="2025-10-08" version="1">MAVPGVPPDIAQLTGPVVIGFAAQWGLFGCSSVQLYLYYLNFPKDTVKLKTLVYGLYILDFAQTLLVTAFVFHMLGSGWGNVNILESVGLSWLALPFFNAISGTIVQCFYAWRIYTLSKSIPLAVVIVLLALCEGTSGLAFSIILETRVPTFADLQSQTFVVTTVCLMSSACCDILISLSMVYLLNRARRESAFGRTEQLVTRLIRLIVGGGILTASFAILDAVFLLAYQNNNYHLAPNSALAKLYTNALMVLLNSRAQFRSNNGNVVTYTFEGESGQKTSRATSGLASMPALDRARIGNGQGIAVDVTVDSTTTYPDSYPMGRFDKRNTDEEFGPVKRGDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSQ8</accession>
    <name>A0ABQ8VSQ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_900501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046654270" evidence="2">
        <location>
            <begin position="25"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="135" mass="14051" checksum="BDF1A3DAED5FB44B" modified="2025-10-08" version="1">MRANFFIAGAMVIIFSILIACSRAAPIEKLISRSGTGEASAADWKRSGTGEASAADWKRSGTGEASAADWRRSGTGEASAADWRRSGTGEASAADWKRSGTGEASAADWRRSGTGEASAADWKRSGTSEESAADW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT36</accession>
    <name>A0ABQ8VT36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HTAFII28-like protein conserved region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_754034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="6">
        <location>
            <begin position="73"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="180" mass="19641" checksum="6255C2D8118D62FE" modified="2025-10-08" version="1">MTTAAGTPLNLTNLFRLSDGVAASSTAAYPRAAGLGGGDDEGEGDDEILPAMADDDYSAQLSWQSQSKDNLKVLMENFSPDQYDRFEAYRRHALPKQAVRKVIQQVTGQQASQPVAQIVAGFAKVFVGEIVEKARQVQARRGETGPLSPDHLREAYRMYQQETGNVGAARPVRAKKLFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT62</accession>
    <name>A0ABQ8VT62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_758799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="214" mass="24184" checksum="AF7781D1B4A8C124" modified="2025-10-08" version="1">MSSTYPQFTFVGYTCIILLIIGNVSGGIISRRAFGGEINAQSAYYILAIMLIFSALMGYRNVKRNTRNHRKWMLRSVVYFSVVITARLIMLASRLIISNIGTYYSLWRCDEVFFVLKDEDTLVQRFAQCASSTPSDNGLYVPVHASVHEGKLGTASAVRVVQGMALWVATIIHMALVEVYIRSTESANHQRHGFVLEARDFDSSKTYSPRNSYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT70</accession>
    <name>A0ABQ8VT70_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Autophagy-related protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_757279</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ATG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01486">
        <property type="entry name" value="Apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006285">
        <property type="entry name" value="Atg7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01381">
        <property type="entry name" value="E1_like_apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="8">
        <location>
            <begin position="6"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="7">
        <location>
            <begin position="348"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="708" mass="78376" checksum="F2FC5C54651032DA" modified="2025-10-08" version="1">MTPTIVQFTPLPSLTHPSFWHKLTEHKLDVLKLSDAGVDITATYRVGRLIEDREGGPGAFVGVGGSLGVEEESFGQGHSSPAIGSAVAKGVVKNYNTIEDFKAADKSKLFNEAADKIWTSIQTARSTTLLNSFLLITYADLKKYRYYYWFAFPAFTSTPAWHIDANPGWISAGTAESTYSKEQMKVIYDQLHSLEQQPAYFLIRSSGSNEINVVAIEDYSPDTDTIETTTIGFIDPSAQPQNPGWPLRNLLAYFRALYPQSTSKLRILSWRDAEFPRGEEGWKSRVGVIFIGPDGVSTEESDTKTRPNAVGWEKNVQGKLGPRMADLAPMMDPVRLANQAVDLNLKLMRWRILPELNLEKISETKCLLLGAGTLGCYVARCLMGWGVRTITFVDSSKVSFSNPVRQPLFKFEDCLNGGKPKAECAAERLKEVWPGISATGYTLSIPMPGHPIPASPPSVLEQTKKDVAQLEELIESHDAVYLLMDSRESRWLPTVIARAKDKLVMNAALGFDTFLVMRHGARPDSGSVDQRDEMGGSKKHLGCYYCNDIVAPADSLTDRTLDQMCTVTRPGLASMAASTAVELMMSVLQHPQGIRAPAPHPSSANATDNRFDEHREGTSVLGLVPHQLRGYLAQFRNLHIVGAAYDRCTGCSETVLKAYESQGFDMMLNAFNDPKYLERLTGLDKLYEDGEKALEDVEWVEGDDEDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTX7</accession>
    <name>A0ABQ8VTX7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pheromone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_610445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="9876" checksum="1D1BB6780D8D0EF2" modified="2025-10-08" version="1">MKTSGTSLIARYKTSKDALIYPNKLALSPIRSSSVAPPTRTQLNFPKPTNMDSFSTLATSFARSDDEVTATSPLPVEEETNSSASNSYCVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU86</accession>
    <name>A0ABQ8VU86_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_914788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="663" mass="74100" checksum="75C893C44CFA1BB3" modified="2025-10-08" version="1">MDHTPGSSISTWTLCTLKSNFGDPPHSRYYYERLLGPNELGFYWDSAYRGTADTLQHATIKETFQSQPQTHLNGKRMRCMVTLKTRYPLLGAIIEERPIKHTVPVSMTLPQVDGAEDLPSGPVQRTPKEDVYFVVDPARLYTAESPHAHPREVVFLSCDSEEEVESLAEGIINGFGWRDVQAWEEGDIPQGRPLSSRLLSNFLPACLLFIRRTDCPSTFHVMIHAAHLITDGIANSTLLSEFLDFLSRGSGLDSLVNVPDKEALEGRLKLSISSEALYPDEAPNYSKAKRRWHRILGKVLLELRSAKLSGGHTLPRILRPSTTYTPAQSSYITYSFTPSETATILRRCKQLGITFGNAHPVLGQVAVTRVLLRRRLRTLSKKRQGIHIDLSEDIDDDEWAYRRREPMMTGGPANLRPYLDQSWYTKGGAGNVCLSISYFFFTLPFMPIGEVGELADGNNEGISSGDIEIPPLEKMLSRARFLLRCNNIRSQASENFHHPRFLDLHVARIPMRVERCRRAALVLRNDIARPEVGSDALIPPLEQPEAGGGAVMAHGGSSFGNSDHLVPPYYPHSATSESAPILHLLKATTRLRCRPTELYLGAATARGRLSLNVFWDENVYKREVVEEWLDEMRGATKWFLGTDEAEFGKGGGVAPPVVVMAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUG6</accession>
    <name>A0ABQ8VUG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">40S ribosomal protein S7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_753281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TTC4 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044059">
        <property type="entry name" value="Csn1/TTC4_wheel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18972">
        <property type="entry name" value="Wheel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Cns1/TTC4 wheel" evidence="8">
        <location>
            <begin position="232"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="572" mass="65093" checksum="8BE7F9FC1FF8339A" modified="2025-10-08" version="1">MAGPQPLTSDDLQAKLDSFDSIPLFMRSLPDDHPVENSTLAALQSLAHEGTPDEIAENFKEQGNDYFKGKRYRDAIGFYTQGIDAKPDSSSLLEALLCNRAACNLALKNYGSVLRDCSKALSQNPKSPKAYYRSAMALVALDRLEEAIDCCTRCLEFDKDNKGVLGVLEHAAKSKATKDKVDLERKEKLRQELLAKAKLDNAFKERNIFVLPQPDGSQNPYVPRFDPEDFSGNSLIFPVFFLYPQYATSDVIPGYVEDTPFFTHLEIMFNPAPEWDTKRQYKAENLVVYAITRRKRLLKVGKKMSLRNVFNASKGKEGDPPDGLELKDNCLTFVVLPKGEVDMKWVEELDWMLEEWMYSLELRMLIRNLVSLGPLKMSVNHKILRTANAPPTPPDEMEISVAQAIIDLENNVPDLKTDLRPLQISAAREVDVRGGKKAIVIFVPVPQLKAFHKVQQRLTRELEKKFSDRHVVFVAQRRMLRKPTRNSRVQQKRPRSRTLTNVHEKILEDLVFPTEIVGKRTRVAVDGSKLLKVFLDSKDANVLEYKLDSFSSVYRRLTGKDVVFEFPVVVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUK5</accession>
    <name>A0ABQ8VUK5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_914934</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF1">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="223"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="745"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="773"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="689"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="488"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="542"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1075" mass="116978" checksum="0939C90F874A6192" modified="2025-10-08" version="1">MAGSILDSNSSPTSLTAAGKRPETTSNDSHNQPYLAPNSHNPHTFPSTLSLDDHDHDVASPPYRPEASTSSLHGQDLLLHPNHPYSSYPPSPAYRSQANMSDELHLDGDRHAAGDAKWEGELRDTKPKVHYPDIEPVPVVSVDAVSPAANKGHLRLDEMPSRDFNRSGTNSPADAMSLAGTDDEEDDSDYDWSGEDDLVDEEAKFEQQMGVKPKKTGWGFKRIVTLLFSSLLGSTLVAGILVTPGILIHFYWFNNNPTSHRKYVEQNVQAWLFWAAANLLLSWYLAVIVDLVPTLATFIIAAVWGHVSEVFKSRVELYNSVKNTFKPVLYAASAWTSWVIIFGHIFNLYDTVDSSQSRAGYTQRLYQVVEFLFFFVLVICAQKMLSHAIAFAFHRTAFKERLDEVQYSLKVIEQLRNYRPKHDRFGRQSGARSSGWAWGTPVLEKAGFGFGKSHNKGLSSSRIHSHRGAEEDGYGADADNEYDDRTVVGTSSRKSTLGSTFGFSNKGKNKNKRQSGNFPSPSGGGDHELGVFSSATSPHGRSPSSPSPDTSRPMTPSTAAPFILNHTNSPTGISPSENGGRGTPHRYPPGSGMNTASPRPSLDSNHGAGASETLAAAAKVLKSAVLHDARNIRGDADQIGNGGGGAIGLGHVGSSSEAKRLARAIYLKFRPLGQGRTYLLPSDFHPAFPDTTTAQAAFRVFDKDNNGDLSRAEIKTTLLKVYKERRFLARSMRDVGIALKSLDGILLFFALVIIFFISLSVFGVQVGDSLSSVYTLGIGASFVFKASASSAFDAIMFLFVTHPYDTGDRCFIDDEILVVKRMGLFATVFARVDGTETYYFNSQLFTKFITNVRRSGQMYENVTLQLHWRTPLAKLDALEKFLNNWLQTEQNRWFVPSTAIMLQSINFQRYLEVTIGIGHNGTWQDWGLRCARKTAFHAAVQHYTRILGIVCYESTQPIVYNNSSDSPAINVLNDGSVPPPSPGGYGGWSGSGGYELEPGPDGGVDIVYGGDGAGAAAEGTNTMSPAAAAALGVGEKESGLKTALGFTPPEGLVGAHLRARKTKSRKVMVGLAGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUN2</accession>
    <name>A0ABQ8VUN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="730"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="855" mass="91387" checksum="58F9642C9E457309" modified="2025-10-08" version="1">MYQQSNLSFSSITSDERRWLDAVTILQDSNTTELANTNAILSNYTTSHSSSSRSSTTVTTSTSTFPRHKNNKRHHYQRSTKSSSAKVVNRMSGSFNRRHSRSNLSSILAPSVSSICSSPQSTSLESPPLTMISSLPPHRLNKRTASYSSTHNGSPGSEWIYRRPKSPSASSPPRPSAIKYARRTVSDSTASVSTPSPASTAESSRCVTPTSTTYRSGLAASYFPDVSTSCLNASSSNLPAHLINGNRDPNVNNGSGSSIGSIGSIGVMIPSSLGLNSSASSLTHQPSLRRSKASSTSGKTGAFWNSILHPRSGPNSVSENASTPNSPSGSRIARFPLGRAKNKQEQQPPPSSPLAVHTATAIPSIWSGAILESANGTSPKRRKARGSLKELGISRIPVSSRITGNRSPASPTFSSPPIYNTPVKRRTSHGRSGSFSSTTSSSTSSAAFSNSVSSISSSTPSSPLTPSTPVSPTFGGFAKTKKFQPKFEPHHRAIVEVVEDEDSSHMDVQRRKSPSPTKSILASRIPYSESSSELINSSSKFDSGVDLGLDDSLRRTNKRKDSMSTTVSSNKSVKFVEKPTVHYASAIYESWDGTIGSGPFEYNNMGIDLSEMDMDTNEDNEGDGYMSEETAEQTAFIHSHPYATSDLNLAGDTAPAAVTAADEVKLNVTTRFVEDFHNTRPTTNARALCAQEREDTCVTPTPDRGRERTSSGSTGTGTLRSFVSLKRKGSSASSTTSSAVKRAPSTSSHELRSNIPRPTISGPYALGTLPPTHLETELPLTSLESVAEVNEKRREIGLRSAGLRSAPSLESFKSVKSGKSMRSLKSLPESVKSNISLRAKGMRDWFKGRVTVGAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUR7</accession>
    <name>A0ABQ8VUR7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="161" mass="18286" checksum="6C8E1E420E9217AA" modified="2025-10-08" version="1">MVMLFIKEHMQKTQPEFEKLVRAKRINEGFAADEKVWVQFKTESFPKVQPQPTIPFEYIMRPPPCVNWVPARLRSITAHTAEIITHKSPVSPSKAKPQARPQILLNSSKANSEPSRGKKQNESLLKDVLVSNAIRIKRRLSVASSLPKERVNVIIYTTSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV41</accession>
    <name>A0ABQ8VV41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_752703</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="11"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="87"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="31804" checksum="0D3674238C31E639" modified="2025-10-08" version="1">MTEFLYFILAECDNCHTTTTPLWRRDRTGMKILCNACGLYSKTHNGSDRPLNGKTPSERRQTASKSKQEQVESTSRLIFSTTLLTSMRSAQECSNCSTSTTPLWRKTDEGKLLCNACGLYVKLHGHNRPVHLRTDVIRQRSRENARVRVKRTNTGEISVPVSRNPSRTRSSTAQIRRHSALEDDDDDSDEGSDEPGYRSIGTQRDSDSDDSDSIGTPDEGGSEHILPPRYGVFKNRFKRQRITIGDSDTDSIASMGSPSLSSLAAVAAAVAAGAYSDSPLSLLVSRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV57</accession>
    <name>A0ABQ8VV57_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino-acid acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="5">2.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Glutamate N-acetyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">N-acetylglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_915216</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">N-acetylglutamate synthase involved in arginine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342:SF4">
        <property type="entry name" value="AMINO-ACID ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23342">
        <property type="entry name" value="N-ACETYLGLUTAMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="408"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4499467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="606" mass="67242" checksum="99392971B412947F" modified="2025-10-08" version="1">MHSYSVPCRQLVRSTIKNQRSQTFKAFYATIQSLRKAPPADIDDVPSDNDFILSILRANASSRDAKPYFASFSPRPRPAPALTQIDEATPVEFREPLPVTEHPKVSPLIASIIDPVIRRTALVKIQGPFNQVQLDSIARGMVYLEKLGLVSVIVVENDDVQRGEQDSRSVIVEDTMRLVSCLEKHGARARPVLGAVVRLGPKPEDPETVQDFVPPEAHTFPSDLVPIRSALRSGEIPVIPPFALDSFCRSVRIDANDVIGALARGMVEAGSQSSSADASIEASGEVDLTPLRVMIINREGGVPSYARTGFPHLLINLDSESKHIRETFHESWRHTHKTALSNLALAKTCLTYMPPTSSAVMVSHRSQSSLIGNLITNRPAVSSSLPHALLQGNRKLTPHTPTLIRRGLPIRVVRTVENIDRIKMNALLEQSFGRTLEESDFYDRLKRTLDFVIIAGDYAGAAIVTNEPSSDLSQPISYLDKFAVLPSHQGDGTVDFLWVALHDESYGLGHPFSANPNGGKEGQGEGRDLVWRSRANNPVNKWYFERSSGHVRMGDWVLFWCDAEKRLKIEQGRRGRAGLSYVEDWEEGRLASWIDVVHKIPSSWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVK2</accession>
    <name>A0ABQ8VVK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_757048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14435" checksum="2C79E3C53BA9E8EE" modified="2025-10-08" version="1">MSHIEGNLPLAMKEENERFFRHFVGTPQTSFGADIGKNIRLTSANVFLPNELEGKTGSEAEKAKKSAETVTICEIDVTKDMCNIYGTLHGGCAAYIIDLCSSTSIVCYGLYTGTDGTGVSSSMNIHWHKPITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVQ9</accession>
    <name>A0ABQ8VVQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_814842</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12577">
        <property type="entry name" value="RRM1_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034156">
        <property type="entry name" value="Hrp1_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="140"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="223"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="409"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="445" mass="48357" checksum="80731E048DD745AB" modified="2025-10-08" version="1">MSDIDADLYGDLYETDFVDQTADEKPTETLVQPPQVKTEVPVTPKAPEAIQTASSNNHSVPTTYAFSNVPTIVAPPVQQIPTYEEVSNDYTSSRLSGIQSIASSEQRPVRPSEMKDDGSLFCLLVHLAPLTYIWNRTLYSKMFIGGLHWDTTDDGLRTYFEQFGKVEACTIMRDQAGRSRCFAFLTFEDPASVNAVMVKEHVLDGKIIDPKRAIPRQEHQRATKLFIGGLAATVTSESMREFFSQFGRVVDSTVMLDRETGRSKGFGFVSLEDANVQPFLGFGNLEIDGKLIDVKLAQPRYQREHFQEDESTGGNDGGFNNRAGGGYANNFQSGSGTAGGPFNAPATTGPSFDPQALAALYTRMFQMTSGGGMNMMPMMVMNNMAGRGMGMASGMGSMGMGRGAMLPEGASAGMGQIPRGPRGNLNGPGPARSQRGQHNYHPYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVU9</accession>
    <name>A0ABQ8VVU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_426005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF31">
        <property type="entry name" value="AMIDOHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G05840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045083778" evidence="4">
        <location>
            <begin position="21"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="5">
        <location>
            <begin position="59"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="38553" checksum="F7BA8B62F36FD26F" modified="2025-10-08" version="1">MAKLFHLFIVAFVVSSFVYARVWNDTGNGTIVFEEAWTIPELTTDTGTLRANLLDIHNQRLTQMDQNGIDFMVLSCASPCIQGISDPTVANAMAINANNQLAAQISNNTLRFGAFAALSMHNASEAAAELKRTVEELGFLGGLVNDYQQSGENNDTLIYYDQPDFDIFWQMVTELDVPVYFHPRTNVEPISTLLYGHAPWLLGPGQEFAVTLSNHILGLCTNGVFDRFPDLKIIVGHLGERIPSDLVRIDTQLLRQVPLGMPMLRNVSTYFHTNLYETTSGNFATTLLQFHIQEIGLDRILFSIDYPFVDIPSGATWVNGLDEVLTPEELLNLKRGAAIKLLKLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW01</accession>
    <name>A0ABQ8VW01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetrapyrrole biosynthesis uroporphyrinogen III synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_751246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390">
        <property type="entry name" value="UROPORPHYRINOGEN III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390:SF0">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole biosynthesis uroporphyrinogen III synthase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="30260" checksum="970B9239ADAAC837" modified="2025-10-08" version="1">MAIFAVLLRAADISSTDKYETAINAIGPRSRGVCVPVLETALMNLENLKQTIAAGPKVDGVIMTSARSCEAWKAVVAQSADEQTQLWSNVPFYVVGAATAASLRELYPKPNQIRGEHSGTAELLARFILEQTPGNRPKCLLYLTGDKNRETLPKVMDEGHVDLVSLQVYKTCGSSRFSHDLGEVLQGSERDAEIWIVFFAPSAAEFVYPHLQARFRFRSTDTQSSKDDKPLVRIAAIGPTTASFLRDNLRLHVDAIPAKPNPDLLVEAIRECLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW43</accession>
    <name>A0ABQ8VW43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methionine synthase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_892942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="380" mass="42285" checksum="A094D0D29C0A01FC" modified="2025-10-08" version="1">MPIPTEVVGSLPRPDYLQQAYAEYDLGNISKDELIKLQDKAAADSLSRMQQTGEIYITDGEQRSSSFATYPVLEYVKPTLSAEGGQYFAIFDDGHHRKLPRLIRGPFKYEKYAWQNFQKSSPLSNGHQMKQAVIAPSMMYLLYPLSEAIEGYPKDQFKRDVVDECEKDIRGCFKAGAKRVSIDFTEGRLALKNDPRNPWTGASLLETFINLNNSVLDRFSPEERVNIGVHSCPGGDCDSAHSSEVPYHTLLPSLFRINAGYFLIQLASENAAMRASIHQEIGKHIRRDAKGVKQIAFIGVINPLDPVVETPEQVCESLMEASKYIPKDQLGATDDCGFSPFSIDKKPKHGGNPDFARDVAFQKISARVQGAKMASEKLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWJ1</accession>
    <name>A0ABQ8VWJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_786620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13981">
        <property type="entry name" value="STKc_Bub1_BubR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015661">
        <property type="entry name" value="Bub1/Mad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013212">
        <property type="entry name" value="Mad3/Bub1_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012572">
        <property type="entry name" value="Mad3/Bub1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030:SF4">
        <property type="entry name" value="BUB1 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030">
        <property type="entry name" value="MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08311">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08171">
        <property type="entry name" value="Mad3_BUB1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00777">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51489">
        <property type="entry name" value="BUB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0137">Centromere</keyword>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="3" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BUB1 N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="781"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="340"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="516"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1119" mass="126574" checksum="1594F841CE77DE13" modified="2025-10-08" version="1">MQTDGLESQRDKFKQRIAAIAFEEDPLAVYVEFVQWTLDNFDDNDPHSGLSQLLDEATKKFKKDEAYKADLRYLKLWALYANRVSQRSAIGIYSQLWKNGFGVSYSLLYEEYARMLEAVGRVEDADQVYRTGVKRHARPIERLKARYTDFRKRHGKKPVISQDISKTTTAAACPPKQLSSAASRYATMLAPPQPGKPPEKLRFDMTLLYTEKTGEFCFEEARTRSMGLLRKEWPVLPVESLAHSARSSSLTVLRPDEGRFGKRKSMLAGEPTVTINTREALEDVFGMYNSPDRTIRMGSKHAPVKKIEPVAMPRMTTSPPTTLGDGIHKSAVFQPFVDENSDDIKPRKTNKPAFTPFVDLENKTPTHKSRSAFAEKEAAHQNENLPQDSKFTKRENNSVESIFSQKVFIPESEIQPLTLREAHTEDHGQPRPKTILTHERAKSDHDVGKASHPVAFRPFVDPGPETSFKVFSRPSEGKSIFTPKLSTMKLSVPPAKQPTFTPYKDPAEDNIHVEPLTEKKHQSHVDYEEPEYDEEFDQGNTLHQQEQQEAIDLDQYPEEDDNDYSDDFIDEECQEDVVEPLREELGEMYDGQEVDYHDVPFGGRFGQFSVMTPITERTFEYTSTSHSTFNTPSILSKHAPVIQEEQDSQLEAAQLVPDGADEFEHENEDEAGGLHDIHPLRLPSEASISTLTQSTSKLSLVDTLTLSSNFKPSNPCNPFDPPIMQALLSRLNADSQFYDFTGTYHNGYDELQKYAKKNRKTSSSSGGGDAVHPLTLNGQKFVISEKLGEGGFGAVFKARDCGALSDCDSDFEDEDEIEGEEASMVALKVVKPQNIWEYHVLRRLHSALPPANRRSIVFPHALYVFRDESYLVLDYCPQGTLLDIVNTAESAGFSQQGACLDELLVMFFTIELLRLLEIMHDIGFIHGDLKIDNCLLRLEEVPGGPSSWSSAYRPSGEGGWSYKGLKVIDFGRTIDTRLFPANQQFIADWETDERDCIEIQQGKPWTFQTDYFGLAGIIYCMFFGKYIQASAIGSSTSPDGKAKFRLTTPLKRYWQTDLWERLFHLLLNPVDVRSDGHMPLSEELGSIRTDMEAWLQTNCNRTTGTLKGLLKKVEMSCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWR5</accession>
    <name>A0ABQ8VWR5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NCS2</name>
        <name evidence="3" type="synonym">CTU2</name>
        <name evidence="4" type="ORF">C8R41DRAFT_907446</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTU2/NCS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03054">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="500" mass="55191" checksum="D3096EB032CD39CF" modified="2025-10-08" version="1">MVSESCGNPSVEVEAIMSRRPKYDKSKICIKCKVNNGAIVVRHAVYCKECFPALLSSKVKRILEPQINPKPDLSRKKSLKASGNLLVGFSGGLGSTTLLDLISRIYLSNRMEIKEEGIAKPRGGKGHPRNEPVWKKVTVCYVEIAAGFSGMTDRTETIQQLVQEKFEALDFIPLRLENAFDPTWWDRVGGKPTSDMNADLINDDLFVSTVFDSPTSEPVQRLRSYISALPTHTAIDSTIHTLIRILLLYTARSTRSSHLLLGTSLTSLSINLISSISQGGGFSVREEAQEEWRSDSMETVRLIRPLQEITMKECSMWAWWNNLRVVGKQRHPGVKQGIGALTKDFIVGLERDYPSTVSTIARTCAKLAPRVGASGSCILCERPLQPGVQEWESRISIRATAPSSPSHSSDSFSLLQSLTPYLCYSCHATLMSRSSKGVSGNITNTSLPLPVWASARLHISPSDAAICVQLDVKEADDEIWLARKVDPNEMKAAIGEFLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWT8</accession>
    <name>A0ABQ8VWT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_751031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="186" mass="21518" checksum="0145C2F533724F17" modified="2025-10-08" version="1">MFYARPNFTPSRYIVVGLPLNRKDQSWYNPPKLTDIVDVLNRLQLSFGSKIVQDPDLHAQAEKSRRFSKYVFPRQYGLANASMFEISKYEPSYIPDFADRDNEIERLGPCKTPRRVKAVLPLLEKLIWRHGKCKYRLLRDTSCPSKVPSQLGMASSLVCNILLNRYSLVENDMDGTLILVRMPVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXA7</accession>
    <name>A0ABQ8VXA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NUDIX hydrolase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_362965</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04666">
        <property type="entry name" value="NUDIX_DIPP2_like_Nudt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047198">
        <property type="entry name" value="DDP-like_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629">
        <property type="entry name" value="DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629:SF0">
        <property type="entry name" value="DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="9"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="136" mass="15453" checksum="0503813F57E13C0C" modified="2025-10-08" version="1">MGNKGRTSPRIVCCAIPIARAAGKVLVITSRKRPDNWVLPKGGWESSDVVLENAASREALEEAGVRGSITRFVITIPTPAATYHFYELDVVSLEQDWLERNERRREWVDYAEAMRRLEWKKELSQGLRLSSLAPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXA9</accession>
    <name>A0ABQ8VXA9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_810463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046694660" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="17527" checksum="28F0E2CE59B57FA0" modified="2025-10-08" version="1">MLALSSASYLLMLLASQVTAFTFNVSVPFPPQTLSAAQLLPNFTGAIANCAANCSNVQTELSGCQDDASCLCATQLVSDLRNCEQCMYESLIAANAPLPDPKAGSTPVLVGYQAACAAFNITLNTTQVALALPTDWDGPFGLGLNIVGTVFTVGAGFILGTSSLLLLSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXG6</accession>
    <name>A0ABQ8VXG6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_284558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="56651" checksum="496AD719270925CB" modified="2025-10-08" version="1">MDRILAPEIVEQIIDQLQDDRKSLLATSLSFKGMLLRSRFHLFDSIEVTVFADPSGWSQGRESSDSRSLSALLRILDSPYSSMGLAVQRLIVSFGFHFPQTLPNDLSRIRKNLRNVRTLHWRDDTWCDVPNAFKTLLFDLNIETFIISGIWFQKASELVEMITMWPSTLQSVVMGSIVCSGDDTTNIDDTYNALTRRNKIHFQTLHSASTWAAHNLFGSMINSSMITIDRFILGVRFPDEEEVQWVNGMLSRYGSTFNEIQHLIPVPIAIELRNRDLPVFDLRDCTNLRVLNIQSIYLGCSMSNIQELLPLATSAVQNIISSVPNPALLEEIRIRFEIDLSEFEAMADMANTSTTALPLHSGDADSVPFMDQFARFHWAEFSKFLLGIPSPGTPAIGVTSDPKSASKHHYSLSHIESESIPLVARYQSLHSPRSKRVHIELGAYPFENKLFEDIFVKNYDEYVKYMYENGLNLVEKGGNELVFSQVQYSNSYEVDRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXL3</accession>
    <name>A0ABQ8VXL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi apparatus membrane protein TVP38</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Golgi apparatus membrane protein tvp38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_750232</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Golgi membrane protein involved in vesicular trafficking and spindle migration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051076">
        <property type="entry name" value="Golgi_membrane_TVP38/TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549:SF2">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="12">
        <location>
            <begin position="172"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4501054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="37892" checksum="708EE26A2C343E82" modified="2025-10-08" version="1">MSFPETYRLVDSRGEPVTHERNESFSGQELYDNNPYRPPQYEGYKPPEMDARFAPQGYAPTHIDLRNTRPQIGRTPSPTPSESHALAEIGNHSGLINWKHISSKEFWFSKEGLKYGLTAAVIITLVVLFAVYHTDIVVFLTPATQWCHDHKFGWLIPVGILFVLSFPPLFGHEIIGMLCGIGWNIGVGFAIVALGTMLGELANFFTFKYCCTARAQKYEKKKISYAALARVVRTGGFKIAVAARLSLIPPHLTTTVFASSGMPLTTFVAAAICSLPKQLVTVYIGVLLEDSIDGTSKKDKIASIAVAVVSGVITSLALKYVNKKMDEVTPEIIYERRKARYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZI9</accession>
    <name>A0ABQ8VZI9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_805837</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06293">
        <property type="entry name" value="Kdo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="103"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="31900" checksum="8ED8B7BCF253CDD0" modified="2025-10-08" version="1">MVASVILVWQLIAICLFHSLWIMLESSTTESLSTLGTGSSLPTTPSNPTFGISPQSSPNYKVTQIRRSISPSSILVPLEDEVEAAPDDTVAEESLTTVTNIGIILNQKIRKSSVGIVWGGRMYLEGLKVSQESIPVVIKLADWEREPEAGSSVSEHGKIIQEEAKFYHHITHNASASDITPRFYGVFNYSGAIALVLNHGGERLKSFDDLNKERKYTLFKKVIELHSLGIQHGDLFPRNILMDNEEVLRIVDFHRSMWKHICPGHKNCVELTKLREALRLPLEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZL0</accession>
    <name>A0ABQ8VZL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_810431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047205975" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9700" checksum="D905EB16CB0249D2" modified="2025-10-08" version="1">MHISSQKCVLYFKVLLFTQVHLHAPVHALHPFSSSLSFQSDIEVHLLHHQYSAFPPLCIILTVPSYCEALAQKACSGLTQTGPKQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W125</accession>
    <name>A0ABQ8W125_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polynucleotide kinase 3 phosphatase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_892314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006551">
        <property type="entry name" value="Polynucleotide_phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01664">
        <property type="entry name" value="DNA-3'-Pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="461" mass="51915" checksum="ECCEB8713162C7E5" modified="2025-10-08" version="1">MSSALQAGQFRRPFSRFSQRKFFTALGPSTLSKKRPAADDDASSMEGSRGPKVVKVHPFFSNSPKEPKTTGTFQWQKSLGARGSCLHGTNLTPVCSSKVAAFDLDGTLIKPSFGKGAVKKASKGAPPAWEWWRDKVPSALEELRLEGYSIVIISNQAIKGTSLTTWKEKVQLIAATIPSVPFRILAAVAKDEYRKPMPGMWNELKRIFKEDGIEIDRTVSFFVGDAAGRDGDFASTDRKWALNVDMPFFTPEEYFLRQPVQTKFKLDGFNVADLSQLPLFSPAHTPVIPEPRKQEIVLFVGYPGVGKSTICERYFVSKGYEHINQDTLGTRPKCVAAVEKSMQEGTSCVVDNTNRDVQTRKYYVDIARKFKVPVRCFVFTGSMELAWHNNLYRAYNLPPSSASRQEKRDLVPYLAFTSFINSYEEPSLSEGFSEIKQVNWIFEGTEEEKKNWSMWLQIEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DT80</accession>
    <name>A0A9W9DT80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_508912</name>
        <name evidence="6" type="ORF">C8R41DRAFT_814519</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000011">
        <property type="protein sequence ID" value="KAJ4484740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DT80"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001193">
        <property type="entry name" value="Rab family, other"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="242" mass="26925" checksum="7DC5A4405F9B08D1" modified="2023-11-08" version="1">MAVNDWDDATELLETYDFLMKYIIIGEAGTGKSCLLHQFTHNSFKDHSQHTIGVEFSSRTIRLGEKRIKLQLWDTAGQERFRSVTRSYYRGAAGAILVYDITNRDSFTRLSQWLADARALASPNLVTVLVGNKADREEDREVEWAEASRWAAENDVHFLEASSLTGDNVEAPFMLAARSILLSIESGILDPEKAGSGVSYGDRALRRVNSSSRLSFGSLSGRPKKGTVKLKMKGWIPGSKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DYL7</accession>
    <name>A0A9W9DYL7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane proteins 14C-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8J55DRAFT_500689</name>
        <name evidence="8" type="ORF">C8R41DRAFT_817035</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000004">
        <property type="protein sequence ID" value="KAJ4492572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DYL7"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4492572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="102" mass="10428" checksum="661AE53CB2E1B9F7" modified="2023-11-08" version="1">MSAYPSYTMGGLCTVGGITGFIRTRSIPSLVAGVGVGALYLYSADNIRKGANNGLEGALGASALLLLSSLPRVRKGPIPALLTVTSAASLFYYGNVIYKLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVY0</accession>
    <name>A0ABQ8UVY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_872430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000165">
        <property type="protein sequence ID" value="KAJ4463442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF58">
        <property type="entry name" value="LOW AFFINITY HEME TRANSPORTER STR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4463442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="630" mass="68955" checksum="B7859EC4729E6AEA" modified="2025-10-08" version="1">MPSSNAESRKSDSSLNKTASVEPVEVGPVSYNGEEYVQSSGVTRMEAIHRSASGRSGRFTLWAVSVSVVVCAWAYSLDQSTTSNYDALATSSFSEHSSGLASLNIATGIISSVCQPFIAKISDIFSRPYTYILVLAFYVVGYIIIATSSTISAYVVGAVFVSIGSSGLSLLNNIIVADLTTLEWRGFVNSLLSAPFIINTWYAGKIVNALSTGEKWRWGYGMFAIIMPVALCPAIFTLIYLDRKAHREGIINLSSSGAARRLALPEGRYIEQARWTVRTKQILSEIDAFGLILLGFGWSLLLLPFSLETYAKGGWHNPSLQAMMVVGGVLLIVYVFYEIYVASVPSTPKRILKNKTFIMAVIIDFVYLMAGEFRDLYFSSYIYIVKDWSVTNWTYYNNTLTISLCVFGIFAGLFQRWTHRYKTSQIVGLCVKIIGVGILLNGTRATDNTAALILAQIIVGAGGAFSVVGSRVASQASVPHQDVALIISLLSLWSNIGGSIGAAIAAVIWSAKMPMYLREYLPANTTDTQIETFFGNIKTIRAYSFDSPTRQGAIMAYQKTLWYLIVPALGTSFIPLIAACFQTDYFLGRQQNAVMNIGPDGSHLDDSEEETITVKPTTLKGKLLKFWAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW61</accession>
    <name>A0ABQ8UW61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000158">
        <property type="protein sequence ID" value="KAJ4463612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="149" mass="16405" checksum="2325ACE53DA917A5" modified="2025-10-08" version="1">MFFLGFRKRFPFQGFRCNLASPASKAQAVPPRVLRRNREVESLKADASRFCFSRSTHSKDSDNELLRGSLRRHSSSSFPSTKVPVDSKKPKSKTTIKVVEDSKASISSPAATAKGKSRQVVVSEDDSASNEVESEDEDEEEDSAPPPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW88</accession>
    <name>A0ABQ8UW88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_144400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000155">
        <property type="protein sequence ID" value="KAJ4463700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="22669" checksum="7BB09430C8DE0948" modified="2025-10-08" version="1">MARTRIRSVSGLVILIFTSVLGYIYSVGTICTLSCSTTRTSEVLIIFVYSLQIRSQNCFLLTGAILLMNTIRLQFSLIVESLTLIPMATTLSNVPSFPDERCLRGPDNWKQFKDYVISAVRSKGLAGYLDGTIKLPMSATAADAKTTPLNSTSPSQEEWQFREGHVSGLIYQNIVDPDSHSIGPEDAAVTMWSTLKGKFELISMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWN8</accession>
    <name>A0ABQ8UWN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_927109</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14131">
        <property type="entry name" value="PKc_Mps1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027084">
        <property type="entry name" value="Mps1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="606"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="243"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="307"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="531"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="635"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4464059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="986" mass="107317" checksum="AA5C0468B2F289C7" modified="2025-10-08" version="1">MSASSLLQDYASPSPMTPLSRAPSVSPSSSESSVIDELSFDYDYDEAGNIVRNSKGSRTSPQSFLSTPPTDTSGVSRLELPKSSSPPLRRASLSRSESAYPVLNGPATASSDREKAYSSSANPARSFHRAASGPIPSTTTADSAGPPIRTLPRTRIDNQYEARQKRHTEEVRARLASIELEEKENAIPIVDDLYGSRPAASTSSSSRLVPPTRATYGSQSLGGLSRPLIDAPQRVMASSSRMLLKGTGTKPQIDRISEAGTEGESDGGEDAYAGYGGHGHGLFENNAYGTDTDADDDEAMPRVIASRSQQSVIPPHSAGIPPSSLNEFMGTRPRRSASLSDTLLNDGPHHVPSQAAQPSQRPSSRPGTSLGLRRELPGLPPRRVADERLESNRDNERDEYQLKARNTPSPPHYASGQQLVVRAPYANHKRRDSDTLRGYSPGGNSPTVMEAPPRLSPSVKGLSGGVSSRTSSNDKNAVNIAAKHRRSPTAPEPATGSGSLQAGVVHNVQGRTWAAGDRDSGDGYDAYSGNEGKEREREARRERGRSQQLALSQVPQAKGPAPPPPNAAQHGYPPALGRHILVQFNPSQSIADRMLMNNAQVNKKVYARLDLIGKGGSSRVFRVMTYASELYAIKKVALDKTDSETMAGYMNEIALLKRLEGNSRIIRLVDSEVKGGPGGSKGHLLLVMECGEIDLARLISERSQEGLDMVWIAYYWQQMLQAVQVIHDEKIVHSDLKPGNFVLVKGQLKLIDFGIANAIANDTTNIQRDHQIGTLNYMSPEAIELPDGMRRLKVGRSSDVWSLGCILYQMIYGSTPFSQLTIYQKMKAIPNANFEIPYPEYSVPVIPASKSSQAEPKRLEHLRRKVRSDVIANIKSCLDRNPKDRMTIPELLQEDWLAMKERESLVPNLTVALLEPTMSAAPTPEPTPTIKDLLKPDEAVINPFYMGQLLRYGIQLGLAGQSLEDPQDMAKAAERLISELRAVQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXZ0</accession>
    <name>A0ABQ8UXZ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000148">
        <property type="protein sequence ID" value="KAJ4464057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="386" mass="42245" checksum="396FA1F3A0E42577" modified="2025-10-08" version="1">MSLPSSSAATGAPNPVPPPVSSPSHPHSTEMTADAAIDELANTLEEPPLGQLALFRSVFGVGVSLVRYIVDDPLWPLLAAAGLPCSFCIRGKKEANCSVVPHLARCSNCDDKKPCVLGRLARFRYFSPFARRFLEVHGDPGQRTRFTLPSEQWRNIAAKIEASTNSTVALIELNSLDEQDQQELDRLELGEFLRKRPQLPRPSTTTSLPSPLPSVVATPRALAKKRKRSIQQEEGGSSSLRKRPVREVSEPEVAPEVHDRKRKRPVGESRDAEVPDYRRVVLVLRPPLVDSSGSVPLTGDRVDEVVHPPTPSEETGSARVPLPPSQAQSSDLLGRKRSNSPGSSSRFIPPVVSERRSAVTISTPPPSQIRIKRTVIETQIDSQSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYG3</accession>
    <name>A0ABQ8UYG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_860384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046857381" evidence="2">
        <location>
            <begin position="21"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="130" mass="14355" checksum="ED1276725FBC5107" modified="2025-10-08" version="1">MLSLLGLAIVGFDILQGVQSSCTHNTLSSETLSGVMTYISLAVFDILATLLVTNRMIQAIRRCGGFRKLARQNLSEYVLRSGVLYFGVVTIPQIIAVVLYFAPQGLYSPILNNFLLVVFHHDRAFSARFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ67</accession>
    <name>A0ABQ8UZ67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="256"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="43185" checksum="B7912FB56F137E7E" modified="2025-10-08" version="1">MSSFRPARPVSSLSKTSTNLTATIDDLALIFTSETPSLEPSSHLTCCCQEECENYQAWQAMKLRVDNQLTLSASVGHALLQRYYQLKENQSFLKSNEEDSDTQITELLRAKHSLEKQFNQALANSEANESSLESLHQELEEAHATIDRLLISNTKYVDLEGRLEKVSRERDNIQQERDFESQRARSAESRLVTTKDKIEKLHLEVQRLKDELKQKSALKMESMSSVVQTAKSQARMLYHKLGSSSTIESVKLTQSLEALSQHNDSLKQHNKELEILLAESREELNSLRQEVEERQVNTPMRPTLESKEIQERKELSGSHLERDSSLIDTTHVAVESKIEHHSRVNVRSQVSLKTTKSTRVISSQLFFLVGMTSYWFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZN3</accession>
    <name>A0ABQ8UZN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000124">
        <property type="protein sequence ID" value="KAJ4465616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34041" checksum="0C1CE4A48BE3CC39" modified="2025-10-08" version="1">MSAPLHRSNSRTRSPQLPTLTTLGEVLSPDLESDGEVEQDQLAFTIEFPSHPQLQLFKTVFNTGKPLSGYCQDDPLWSLLAEIASPCSNCSKSPANCKVLPNSPRCTNCSAKKTCSLGKILHYQYFARRCNQDLAYSRRLLELHGTPAHQSMWGIPVSTWCQYDAALHERTSSTSTLLELNMLDDQDAADVDQQELRDFLALQQGESAIAAKRKRDLSPLPVAGPSSKKVRSKKCPRRRSPVEETAQESPCRVRLVVPPGRSMPPSTSTLLPPRASPSLMEVPEADLPVQGHSSLVWLAAVAEAQSGLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0K3</accession>
    <name>A0ABQ8V0K3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_778877</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046261041" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="21"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="21"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="261"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4468071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="38175" checksum="6FC00FCB4EFE952C" modified="2025-10-08" version="1">MLRLAFSLITCFLALPCVSAHGYLAYLGIDDNQSYTNYTGNVPNADPSPSVIRQVSDISPVKGASNPDLNCGLNAQFASKVASANPGDLLVFDWRGGDNTNWPHNTGPMLTYMTSCGSSDCTQYNSSSSKWFKIAEIGIVTNATSSNSPVWAQQSVMNGAFTNVTLPSTLSPGNYLIRHEIIALHLATDLGGAEFYPACSQVKVGGSQTGMAEDSEMVLFPGAYQDTDPGIYDPDVYSSNSYTFPGPPIAAFVTASASSSSGSSSPLTSSSPAPTATTGSTPGSSSSSSGAQTLCRLQRRTSSAGSDFTRRSLTRNSNMLLKTRVTHSWNGHRLRGLWGDVVTAFGVLRLRAIRVADGQSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0M8</accession>
    <name>A0ABQ8V0M8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_778935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4468101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="357" mass="40487" checksum="6C0ECEEFBABEDCBE" modified="2025-10-08" version="1">MEALLFNVDGGFLEGTVRGYKAGILTQSHYANLTQCESLEDFRTQLSATDYGNFLANEPLPISTATIADKATQILVDQFKYLRNNAVEPLSKFLDYITYAYMIDNVILLITGTLHERDTHELIERCHPLGVFESMPALCVASNVEELFQSVLVETPLAPYFRDCLSASDLDDLNIEIIRNTVYKAYLEDFYAYCGSLGGPTADVMQRILSFEADRRTVNITINSFNTELSKDERARLFPAIGRLFPEGNNQLAKADEIDQVRSVCENVGEYRQFFADAGSSSNGPNDEDSGILSQLEDRFFQTEVHLNKMAFLQQFQYGVFYAYMKLKEQEIRNITWIAECIAQSAKDRIQDFIPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Q7</accession>
    <name>A0ABQ8V0Q7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045868453" evidence="1">
        <location>
            <begin position="18"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="93" mass="10126" checksum="8B5DD7A48EE66152" modified="2025-10-08" version="1">MIWIFLNLSVLWASAHSANGQDAEAEVEDTICAYDPHKQLQRRATDDSGNATDVGVGVNVPSVGLTLGNITTKLGNINLTYDQDHFLCFFDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V241</accession>
    <name>A0ABQ8V241_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_852107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF3">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="3">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="2">
        <location>
            <begin position="237"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4470285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="322" mass="35850" checksum="28EBFE487FAE93D2" modified="2025-10-08" version="1">MASQYKPIEILFKHADGIDISMDVYLSPSASSQNPAPILLWWHGGGLLQGTRKGVSPHHLRAPANHNITFVSADYRLAPQFRLPTILSDCADAIKFLHSDQFKKATEGRADPTRVILSGSSAGGWLSLLCGYGIGFDEAGVPKPPSIQGVVPIYPITDLEDPFWNTTQRPVKYMDRVVAYEEVQPFLNPNDPESRIASSALDSPRAIFYSYMVQEALLADLLLSGTNIPPTTFSVARYLKALSSANKISVPPTYIVHGDKDLKVPVEQSRDVVEALEDLQKPHVDVEYEYEELPGLDHLFDREPKSQMEKMYMFIQNVFSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2F5</accession>
    <name>A0ABQ8V2F5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_780747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="19111" checksum="F818D6D0B6E6F6E1" modified="2025-10-08" version="1">MSNVNDFSSIDATRPSHHVHGSEDPLPGAKRGGVNPIDYSAETMERTPSAWNEGTERKFAQDHPEIMGAQSGQGQTHREHHHDHHHEHHDRPQEGRNAFSEQRPMDVHPTSAGGVAVDGNSDLPEGKASVMDKVVGKTQKIIGKATHKPEMHEKGELRETGGKAAARGEARALHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2F6</accession>
    <name>A0ABQ8V2F6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="548" mass="61418" checksum="CD2B84BE3291609D" modified="2025-10-08" version="1">MPRNKHALFSKHQNKNSRSRFSSATATDQLHHFSRKAKPKNTGDESDGEEMGDNNSEEEPEDSHVAQVLRNITQKGKGSSTLARKAVVASIKASSASSSKLSKAKEETNRTKSGLLGTTPVQEAEAHTEFKVMSLSIYPVGTYLVEEGYFPRQKPTKVYHDLTSLVDIGCAQIATISQPIVFDRKDTYEEVTDRLRALCPLVMEYANSQFMYRKKSNPEYPKHDSDPAHAYLPEIILCKKDRTYGMLLLTGPSSFFPDGEMLWRIATKHGSANTNALTREPISKGRLSLFQEAIQKGKQMNVPPITAFYTLEENTELSTENKEEEEEEEVTDGSKEVEENTSDKDQKDYQEDKETEVEVEEIVNKGAVSGNSEEEEELVEGALRPPFTQKRLRSESEPSGQDERPSKKRKGNGLRSYSGSSSEPQTEEAEEDTTNTPKPRSRAFLRQTGSPHMRSILRNADRARKLDEVEDDLGFRTDYSSDREYASNLFEKPTSSTPQVNTSAATVSTSQASTSTSNPSNSMAAFLTYYKPPLSDKSRERLDPWKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2H4</accession>
    <name>A0ABQ8V2H4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_612884</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RFT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007594">
        <property type="entry name" value="RFT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117:SF5">
        <property type="entry name" value="PROTEIN RFT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04506">
        <property type="entry name" value="Rft-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4470742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="553" mass="60761" checksum="95E5C114E0C1B0CE" modified="2025-10-08" version="1">MSSTTSTLTSLMGLQLFTRLFTFILNQALSRLASPIAYGIAAIQFDLMLSTILFLSREGVRGTLLRVKPRSETEDTGKATLDRKKEDSTMNVSFVPIIIGVPLALVTSLLYMATAGMETRRQPHFQLAVGIYVAAAVMELLAEPMHNMAMTSLKIHLRVRAEGVAITAKTLATFLVLVYDASRGDEGGDLALLAFAFGQLLYGSSVFLIYLREFGKGGLITRMKKNSSGIYFNHDVLALSMTMTSQSLVKHLLTEGDKFILSWFSPLQDQGGYALAVNYGSLIARIVFQPIEETLRLYFSRTLADITVALSPPSSTQASQTSIPALKKAADALITLLQMQIIGSLFVLIFGTNYITLLLNVLLPPQYLNTSAPRVLEAWIWYIPVLAVNGGLEAFIASVALTKDVNKQSRWMVLFTMLYVTSAIVLYRLDLGDAALVYANIINLSARIIYACHFSHTFFATHNASSTLKWREVLPPWSLVFGLTISALLIHLSETIHGATKAVQKEGRIGILSRPVLIHVAVGGILALSCGILWAWSVRRFLTIPTRFKPKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Q0</accession>
    <name>A0ABQ8V2Q0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_851520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4471010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="130" mass="14238" checksum="AA79F8DDF911F769" modified="2025-10-08" version="1">MSWLHSVQFSAKGRVQNSDPLLSRQTKKNSSALAQKDHRQESFSVLSDATVTMLIALKDAAVIAPVPYIGEAVGLAIGIWKNVQTTRNTKTSLKYLGQDACNIVYTVLTVERGYAVHTSLIRSCVILVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R6</accession>
    <name>A0ABQ8V2R6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartic peptidase A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_924994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF75">
        <property type="entry name" value="ENDOPEPTIDASE (CTSD), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045711189" evidence="5">
        <location>
            <begin position="27"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="192"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4469804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="513" mass="53094" checksum="99BBC302BD52E909" modified="2025-10-08" version="1">MQLQLSFATLLAGVLFAFSTVQDAVARPTRRNSGLVTLPLKRVPRAEGVPPTVYLQQHINRAHKRLARMKGREVPSDHQLRQNIERRMLALEEDPLSKRFNRQGVKKNARSTNRIGLAGAAHNSRSLQLKQKKGGNAGGQAASTAATTGDNGTAGTGSEIEANGVPSGVEAANAPTASNSLGLNIEGQDVGYLATIQMGTPPQDFLILMDSGSADLWVGSESCTSTAGGGCGSHTFLGTASSSTFQDSGKQFAVTYGTGNVAGTIITDNIAVAGLNLTGHQFGVADSESDDFADNSVPFDGLMGLAQSTLSEQGVPTPPESLASAGLISDAITSFKISREADDLNDGEITFGGLDSTKFDSSTLTTFNNVNADGFWEGAMDSVTVDGTDTQLTGRTAILDTGTTLIVAPPADATAVHQLIQGSASDGQGGFTVPCTTNASVALSFGNTAFAIDPRDIAFQPVDPNDPTGDCISGISSGEIGAATEWLVGDVFLKNAYFSVDVGKNAISLAKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V336</accession>
    <name>A0ABQ8V336_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-serine/threonine kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_926056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="32248" checksum="43C54C47C2819550" modified="2025-10-08" version="1">MDCEAFDAASRISLQAQHSPNKEYFSRANQELVSGKSVLLSYLLLVLLNLTSEEHPQLRLRAAPVFLYTDTDKILFFGSHIYSPKAHVHFTPQMLPEPKSSELTEGPDGAQHEGLVDVGHIFIVQSSSPNPSRYHYWVNWKNAIVIGLPLWSRELLIQGWKYQHARRKLDASLNHWVKKQRVARGLSTAEDEGIADMDLLDVRDLSLSGLNGFQKEMFLELPQQHRTTLEDAEVSDAELQSPDVLDMIMEKLLNNAIEHFGYAARDIYTYLRNPAAVLSVHDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3E1</accession>
    <name>A0ABQ8V3E1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_777142</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4470736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="269" mass="28781" checksum="88809876BBE51E50" modified="2025-10-08" version="1">MIIVSEVGDKTFLIAAILAMSNPRLIVFAGAFGSLVAMSILSSAMGHILPTLLPRRWTQLAAGILFLVFGTKMFIEGRQMKAGNEKTQEEMKEAEEEIEEDEARHEGIPDVDSASLDNGYLVPLGIIEGGRSPVFASKDSTLKPKSKKTSLVEGARNFCSLFLGPVFVKAFALTFLGEWGDRSQIATIALGAAHNAYLVALGTIIGHGCCTAAAVIGGKYVSTKISAKHITLGGAVLFLLFGVLYLYQVFMDSTADDVSIPIINHPEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3N1</accession>
    <name>A0ABQ8V3N1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_924352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="324"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="562"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4472682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="600" mass="63444" checksum="DCA590698239CE02" modified="2025-10-08" version="1">MVSPLWIASSEGRLEEVQDLLRTASNADVNVKDSNGITPLIEAVKNGHVEVVHALLAHGADPMSASHQGPPQAYTQDPTMLEILNPAQVKIVSLAPPNETGFYSEANGDPYAPAAYPYYPPYTTSPPEGPVYYSPPPPQVHADGQSMTAPGPGNLPPPEIARLIPCRYFPACRYGASCLFAHPQGPYLSGPLPPPAQYPAPYDPMNSNYPPNDYYSMSPPSFQQPSPNGMNIISSPNGASVVPPEMFPPPHPFSPNGVPQVPFTAVSPIGEPAPYLPQPPMSAAPPQIYHQPPPPPPPTMYNNTSVPAPPFVVQSNGISQYPPIPASAPVGYSDGVVDPPPSNPQSETFGSIPTGPPASHRESTGHARRSSIRRGSFTTRKPPCLFFPAGKCKNGDDCRFPHILLNDYPSPPHSYAAGRGGAFRAPRGHPNHNSVGNGLDAKMADLTIRDTRPQNGHPVKIESKDGNRPRPGQGYKNASNKRPPPIKQQRVPNADEFPTLGNLASPPPKSSSVYFPNGNGHSGPTAAQVLLAPPPRRDSESFPSVNGTRTPSDSGSVKDSDSSIVAHSSSTSDIQKLPISFAAVAATSAPEVAAEVSVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3P9</accession>
    <name>A0ABQ8V3P9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="701" mass="80077" checksum="1790824F7DF737EA" modified="2025-10-08" version="1">MGTQVCLLIATCNLKIAHNSWLTRTKIFVCSSPPATSRGFTLLQIKENLSHQNKLSNEATCRFTKSNTTAHIRADNTTKQYTQVIQRVRKWLEEFLKVEENAEGCLEDEDEDISMRNEEMASEFYGCLEGKPNQFTPEAIAMYISWKCYEEGRKLSTGESVHAAFKYHYTHLEGNKYRGDWRYDEGNKQWIGNPCNAAEVVDLMEGYFAPAIPCLFITGFYYLDKAKHVERNPLPRPGATPSDPSFIQINLRDRKNWQKKQAKNETQLNGHRYNLYPQKIRAICAQTHLSIWMEFCEEHILRRQYEPNDYTFPTINANGVTFQSKQPITPEAVQKRIDNFTVAAGVPGAFTTHCFRRGGAQYRFMFAPIGECWTLACIQRWGGWAPNEKAPLTSIGTSHTSSYGLGGYRVCLGPVWRDTLIRYLLDELNMYEEDHSNALAPIDRRASESHAGSTIKKEFAAIYTSQHHHLPQGSAPYGPYPYQGYIWPSLPVPKPSLMPSLSSYLSQMAAPAPNQVIYSSTGSFTPQPSTKILPELDYLAIIPKIRPSPSAWKQDWKPEWAKVTQQAALYGQRKLIALEFIERFKRDDLAIQQAYDCCQDGITQLLLQIRASKQESGTKGATYISPIKLEFAMVHNIRYKVAFTNDLEVTPQKLGWVAREELSLELVEVKKTDCESKSELIEVKGKVVNRRREKYRQYVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4G2</accession>
    <name>A0ABQ8V4G2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serpin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_778528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000099">
        <property type="protein sequence ID" value="KAJ4468946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846:SF11">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11178" checksum="99BD223306A2D52A" modified="2025-10-08" version="1" fragment="single">LQHESVGRMAGHTTEQLLAIRLAPPFFASQGVNLTSILGASGVLTFTLIKNVHVPDDVFNALKAFLNDSQLVEATATAAGYSFINRFVVALNVDAKMDVPVPVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V567</accession>
    <name>A0ABQ8V567_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Terpene synthase</fullName>
            <ecNumber evidence="6">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_780387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the terpene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4466569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="42136" checksum="C7926968A26C2CA6" modified="2025-10-08" version="1">MVQAKTKTFASPRNPSPTTANNFILPDLISHCRFPLVYHPKGDVVAAESIRWLDTNCPDLREKRRRALYGLRAGELTAFCYNTASDERLRIISDFMNYLFHLDNISDGMMTNDTEALSDAVMNALQFTDSRFYRPTTELNYVQLEDELNAAKLARDFWGRCIRGAGPGCQSRFKDNLGLFFQAVSNQTKSRDAGVIPDLESYIEVRRDTSGCKPCWALIEYALDIDLPDFVVEDPIIMALNQTTNDLVTWSNDIFSYNVEQSRGDTHNMIVILMKHHGHTLQGAVDYVGNLCYQTMEYFNANRSKVPFWGAEIDDMVQRYVQGLQDWIIGSLHWSFLTTRYFGEEGQDVKQHRFIELMPIREENKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V586</accession>
    <name>A0ABQ8V586_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_848610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="87" mass="9718" checksum="EE954EFAC35D34D8" modified="2025-10-08" version="1">MSFWLFISSSMNPVSSAIVELRGALFPQKIPRFSSTTNIETEFEVWNVMLSEEQARSRCLCSIKVSRCSCKDGSSWGVSSTSEATRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5B7</accession>
    <name>A0ABQ8V5B7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Abscisic acid G-protein coupled receptor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_549841</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046300727" evidence="6">
        <location>
            <begin position="25"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="8">
        <location>
            <begin position="184"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="7">
        <location>
            <begin position="323"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4475138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="556" mass="61846" checksum="72663E4148EFE1A7" modified="2025-10-08" version="1">MMSIFLESLVLVLFRAALFLSCRSFVLNRLYPDLQNISTPSDEHDDVELNVLPTHAKSNSGRATNTGYPQSNTMHSKISRTVFAGCFSESCILFVLLMCQGLGLFDPTTRLLHWKFSLFILLLTILVLGPLLLSIFISTDSHKTSRRLPYIRLFISLIPVALSLFAISRIPLPQALRNDSKIDLITSSLARLLVVGTIILGLLSGFGAVSSSWTFLPSCISSSSTQGSGIPSERDIEQTERALERVKDDLTTRKRQLEAKRNATSSSNSGAPTSAGASWYSRIVPNLRGNDDEAEVAGLQLLYEQMDHNLSDLRRRKQDELFQRTIWGRMYGVVKFCMAIYWIARIIWTIVKVLIYRNFFASSLSPSTNYPDLISKLLADLLSFIHRRHFEGPNHDLLTGSDNGQTPADLGETQEKIKVIARQISLLFVGLVVLISIRMVLRGVSRILSRMTKLKLRRNLGASVMLVLLAQLMGIYLLSTIVQLRASFPPPAVSSSSVPELAFESDIAAEEPTNLFTTIPPFEVFGSLFDGAFLLAATLSILVRWMGNKIGAEWDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5C5</accession>
    <name>A0ABQ8V5C5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_847345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="765"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="895" mass="95504" checksum="64A12C63928E9D7C" modified="2025-10-08" version="1">MENFNDMFDSVKAETLRLLVRDLGQKSVGKRDDMLEFLKNRLFSGDVPRTTRSTAAAGTHTNQKASTARKSLSAPGPTRSGRKRKVEEKEEELGNDVSVGDEDSAAKRTRMTRASNSKVENVIGHDHMDSISAGPRRGKRRATSPKSSSGLGSQRTSARTRTLTAKAAAVTAGTKRGRARSSKNIAAPSIQDDLSDADAEGDEDEYVEHTEEPIVERRGRGRPRKGTEIHIVDEDEDDYVEEAAEESSAERRTRGRPRKAQKNGMQLADRGENEGVEEPVKRGRGRPRKDQAASASAPVSRTVATSRKSRSPAPISHASHGPMSTRSRTGHSPAKKMNYLTAPLVKHTYATGRKGALRSRGRPHKYPAAARGRRPRSSVSKPITKTKYIPARSRPKENSDRSSASGSSGGKKYTFDGVELISRNRGWQGQDAAGANAEAGPSTNVRTTLEGVKNADADVDADGDTDMDLLGGAVKSHEGEAQHRSTPLQLHTSGDVNRPTANFKNESGREETTSEAPRASVSELPTKQQPESKEEVHRAASLAPSHHSSSALSSVRGAVVVVSPTASSNAAGDSSSSYFIPPPSGIHVQPQADVDAAAGQKVDLNEQGHPQGLLVQEEENDASKTEGPATQLSGVAIGDILEQDKEETGPIISSSSKSPTEASAVVSTTKELSIYSAAAIATSSTATASHSMPSIVTQDVVDEGSNANLQSADQGSENSVDIDVGNSKLGDLESVDEDDTSIMDPPIGHAIEVVVHTEKFTITDTNTSAANPATISVDQPQEPRQELETSIPNEFTEVNASGEPSSSAFPLPPSAPLPTSAQIQASIDSLHSLHSRPAEDDTADNALFESTYIDDYDLETDEGEVPDDNGRGTGNRTEMEQELNNQHLTRSDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5K1</accession>
    <name>A0ABQ8V5K1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_850016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4472367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="37482" checksum="4058B1E1B750AF22" modified="2025-10-08" version="1">MGQYWAIISIDNRETARHLGKLGEFFWMPDDSLVSRLTTPVIPESYNTDSAIGVFEGKKAKKNYPPSILLSLPHELLLEIAEELVEKYLDLICFSLTCIDAWELTEQVRYKSLSQKIKRKSWAGSRIILLGDYARALPKGLLTDAEKKELKLDGYADHELGSLLYAHKAFGMPSYKIPSDLYYNIMVQDNDLLLDELRYFARRKPFSQWIRLPGNFKLTKSSSSKDLWMVRNLTKQEYVIPTRPQSLTQVVYSLIGCSSDASVSMQGERCSVLINGPWAGDRIDVTLVSIHRQEHAPEEGSSWKDITVSVKELLEALAIDDDDYGVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5R1</accession>
    <name>A0ABQ8V5R1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_983972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="482"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="888" mass="99887" checksum="A416F8A60B24C624" modified="2025-10-08" version="1">MEPLSANDITAPAPLPQTPKPKQDHGPPVVESTPMSRRCTTHTEDEVPKRADVVNKFLEDDISDRLEVSLDDFATLILDLPDDWQIRDDFTLLPDSEAVKDAFAAYLKVAIGEVDGENQKRKGMAGHESGLYQPLANLLNSLRDGEGRRVGKDIDEKIFYVQDPRPVLGSLIARKPDLGGIYIELLKLTKNKKLSDYLAKKKIVGVFWGLLLYFIEVKHEQGRFVGLNVKKEETGTPTNGSSRSGVSKQHGSRQASQTAEPSILPTPQSGPSQSQSTKRTRPYEGPDATMARPNKKVKSHSTSQSNSQGWRKSKRISKRAGPSSRSQSDMLPSIAHLVSQSTASVPASTPLNSTSTSFGDEHRPGVTIQNRGGKKKTVEILTSQDYQERAEAERKAEKVLTPTQGQHLTRIQCASYAKEMLSKGFIRSHAVGITADDTSLRFQYYDRSKVVESKPFNIVNDEVKKLFMAMVCQLNKLSTENLGFIPNLDVDGFDHLRNPKQLKLPHKNGIDPLVGSTYTFTGSDGRRRRVKITKVLYRAEGIIGRCSIVVEVECLCTEAGCDWHEEGKATTKVMKISFPSMTRPSENGLIVEARSTAESSGDLWALNHLPEVIDSITYPYHEETTVQGRLKKHLKDDYEERVMRVTFLDKLQPLSDLEDPREFAQVFYDVLQIHQWLYERVGILHRDLSSGNIMYRRKNGKVYGVLNDFDLSSRVRDMDKGATSKQRTGTRPFMSIDLLNPDWEGGHLYRHDLESLFYIMLCLACRYEAPGVPAPEPRPYSQWFSGTDADVLDNKSKFFLNALGKGLPVQTYFSGFDEGLWEIYTEIRSGYMQRPLVHTKPRKSGAVKNSTFEWTTMNEHVSYAMMRSVMSSFEGKPLETRWVGNPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V791</accession>
    <name>A0ABQ8V791_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="571" mass="63237" checksum="2054559172ACCC4A" modified="2025-10-08" version="1">MSNLPPDAIYNSLLNFGLPQGSVTLDDFSRIYRHGGPLQDAILFISEHFRGRRGIHEARSGLFCASESRDESQINPARLTGNIASLRLTKSKKDAEIDVEYTLTQHIDIPPIISFKNFGPTRTLNRAQKNRSISSNHSSQRKDRKVPHGQSAISKLEEVIQLIQLFECEPSPSGPNSNLNLKKPRQTQDALLVLNAYHVCLARLAAQSTQTLETAENTRDTRARPHSPVPSDTVSTRNAARKPSVPVASNNANVVVTPSASAEVQLRALVARKLGVEGGNKDPENYICTRTALVQPASNDIQMCFYSEFMLTTEHHSQGFIKVAKARARNQVRYTGNMGIGEPVSEEKLDTLAAEVNKKTQILQHASDLSLELACGTEHALVTISNFQKTTISSFEEILNSRLSSIRSYIDHLRIYVVADSQRDAQQGTQNSESLVPNKPSTRVEPDFGHEVRKILGLSEAETSKKVLEEIGRLVNTIQHKSRYLEAMQIRSRDVSSSQRARETETIASYESQKQQIEDTIEKLLIRKIDKADSLGHSLVQDIEALLIGIDDIVGHGNSGTRRGTTAILKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7T5</accession>
    <name>A0ABQ8V7T5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_924323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="157" mass="17727" checksum="93E626C5BB1AE161" modified="2025-10-08" version="1">MPPVFRPRLSRREPRFPTIGAVLEDSHRIRQSSGFIELRPSHVFTSSTMLKIPAPQRSNELVDYEEEDIEEIDGVLVYGIQSSFLIPDWIFDETANNNSVTFAQSTSEPGPSPESKTLQAENVPSSQRGHVVKIVMDKAVAFARRLFPTTRASRTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7W2</accession>
    <name>A0ABQ8V7W2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_843256</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF88">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN CTL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="554"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="645"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="554"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="688"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4479400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="730" mass="79273" checksum="D7AD4AAD765748C2" modified="2025-10-08" version="1">MASSFAVYASQFLNNTRGTESGAEPLFYSFTTSEGGEEEYDLDTDDPHLGTGWLADQGLGVEVEEGSGERSGEGSEDGLVESRVESLTESLLVTNEGFNLPDPRRRVKRQDVGWTWMWGICVGVCYFIALVSPSGSNTRGLLPLLIPLIFLSAFASYLHILFLRLWVRPVMLLSALGTPLLLFICALCGLASSPLRLLSLLPLFLSIHLLHRLYTLYLSFPLLLTHITHTELTLALSTHLLTHHHPLLLLLSPLLLLAFLLLSIPFAVVVYTAPTTPSALFAAAVWVWSWGITRGVLRVTTAAVVGGWYFSVPWAPPVSDSPVWHPSSPSTLLLRAALTRASHSSLGSIILSALRETSLSTISLCIRLFLSLPILLFSFLSSILPTPTPFPFLPRFLLQIPLSPLTRYISHLIPHTSPFSQIYIALTGVPYRTASLRVSQTRFTGTGGGPERSRGQGGLVGGSGTFGGFPSLLSPLSPPLTLPLPFALITYYYFVSRSHTQSSQTPLATPRFGTLEPLLAALLAALTTALVGIFCVGVVRDVRDALGVCWVGDDGRGETESTERTARTATREERGRETLKTETQRSESTRTFKTTETGREESREGKTGRLRLGTGIDQHRRLVAPVFEYEAEEDEEVIHIHQIPIPRDGISSNPSIPRETIPPLLDSDDEDINPFHHSPNPSKPSPPASASSSRPPAVSAPVRSSSSSLSSLSSSGEEEEGGFFGSGLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8A4</accession>
    <name>A0ABQ8V8A4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pectinesterase inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_842969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="23552" checksum="90692D0F02280A7F" modified="2025-10-08" version="1">MPIISINGVFLHYLLSTVQSNFSYRLPIMKFTIGLSVLAVFVTAALANIVPRDFAMLKNDANVVNKDCLALKGAIEQLKAPVSAPVLLSLITSSNNLSAALITLANDAKIAGVITDAQALALLSISENSIDNCMIPALNELSANAILLAAVKTEVEAELKKLQASYLACASNLIAICPVSTLSPFPSLINFHLFKLQSAEKPEASQLAIKPNAALATCLKAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8B5</accession>
    <name>A0ABQ8V8B5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_775170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009945">
        <property type="entry name" value="PRK13409.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="243"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4474184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="56604" checksum="5FCE3306A533CD7D" modified="2025-10-08" version="1" fragment="single">PRPGQVLGLVGTNGIGKSTALKILAGKLKPNLGRYDDPPDWQEILKYFRGSELQNYFTKVLEDNLKALIKPQYVDHIPRAIKGSMTVDKMLDSKLELDNKQRMCDELELNEVLQREVSQLSGGELQRFAIAMSCIQKADVYMFDEPSSYLDIKQRLKAAEVIRSLLTPDCYVVAVEHDLSVLDYLSDFVCCLYGKPSMYGVVTMPSSVREGINIFLDGFIPTENLRFRQESLSFKMVETAEEIMVDKTRHYTYPSMTKTLGSFKLTVEAGSFTDSEIIVMLGENGTGKTTFVRLLAGDTPDIETDKQTLSVSLKPQTISPKFPGTVRMLLLKRIKQAFMHPQFQTDVLKPMNLEAIMDQDVKTLSGGELQRVAIVLALGMSNVSVYLLDEPSSFLDSEQRIIASKVIKRFILHAKKTAFVIEHDFIMATYLADRVIVFEGEPAIRATATPPQSLLTGMNRFLASLEITFRRDPTNFRPRVNKLNSIKDREQKAAGNYFFLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8M8</accession>
    <name>A0ABQ8V8M8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_495843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27860" checksum="E1466CF95AAA5672" modified="2025-10-08" version="1">MGSLTTFSPYRGLEVLSFRGPWAYSEVEYDDAANRFYRDVLLMHADSLVKLELRVVFESRWCFGEHNVEAFRRCRKLKSLWVKIDHRGLEEDPTPYKPDIYADNNSPLRTPFPNSVHLLLKMISSYIPDLERLTIEPARNPEWAHHRGDGIWLLGAKFCLGIRRRLHASVQSFVAWDSSSTISVSGDVRNWVRVYVGNERVVVPVQIPSHRNGMVSFKKKSAHPVSILQKVIRRTKSRITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8N9</accession>
    <name>A0ABQ8V8N9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit beta</fullName>
            <ecNumber evidence="13">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_897281</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="208"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4475808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="538" mass="57618" checksum="9069A57A6F143905" modified="2025-10-08" version="1">MLTTRGAVARLSRRAASSAKKTNAFFSTAALSQRVPSQSSSSRQSSSRPQRASSVAARSYATEAKQVVGSVKTVIGAVVDVQFDTENLPPILNALEVQDFHGGRLVLEVASHLGENSVRTIAMDGTEGLVRGQKVVDTGAPILVPVGTGTLGRIMNVIGEPIDERGPIKGVKLSPIHADPPPFVEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVLIQELINNVAKAHGGFSIFCGVGERTREGNDLYHEMIETGVINLEGDSKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGGMQERITTTKKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGIAELGIYPAVDPLDSKSRMLDPRIVGREHYDVATAVQKILQDYKSLQDIIAILGMDELSEEDKLTVERARKIQRFMSQPFQVAQVFTGYEGKLVSLKDTVRSFKEILSGAHDSLPESAFYMSGTIEDVKAKAEQLAKEMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9E8</accession>
    <name>A0ABQ8V9E8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_896791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03382">
        <property type="entry name" value="PAP2_dolichyldiphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039667">
        <property type="entry name" value="Dolichyldiphosphatase_PAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="58"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4481856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="245" mass="28165" checksum="6DE128C8CE9C2B8D" modified="2025-10-08" version="1">MFGSHSANRGPQTSLDLTHVLYDDDSLFSLALALVTLSPILLMAAYASLAVQTREFLVIVMWAGQFANEGFNWILKRLYKEDRPDGSLGNGYGFPSSHSQYMGYFSTFLICHLYFRHRFASTGSLYLDQAWRILVYIAVSAWGLLVAYSRYHLQYHTPYQILWGYGIGVVSGAVCYGCFELIPRIRPKSFLGQFKMFLVSNPVSTWLQIRDGWAIWSDGGREGDWKRWKAEWDKQRITSHDKRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9F3</accession>
    <name>A0ABQ8V9F3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aquaporin 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_774688</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4475130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="25483" checksum="B3365DBA1B0B3F66" modified="2025-10-08" version="1">MLLVVFGIGANCQVTLSNNQNVSAAPKGSYTSVGFGFAVGISLGVWVSASRSGRHINPAVTIALATFRKFPWRMVPGYIFSQLLGGFIGAALIYANYYHAINIFEGGSNVRTLLTLDYMTNVSAFFSEFLGTALLVFIVFAATDPRNAIPSAAIPFILFTVLLGIAICLGIETGFAVNPARDLGPCLLTLIVGYGGAVYSFRHQYWLWGGILAPILGGVTAASFYNLLFIDSGRFRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9J6</accession>
    <name>A0ABQ8V9J6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_770684</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="39"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4481821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="48062" checksum="D978C4F09B76F768" modified="2025-10-08" version="1">MLKRRFVPCIFDEVENVEDYQPGGFHPMRIGDKFDNGRYRILHKLGNGGSSTIWLARDEHSSEPGLGKLVTIKALRADASKINSPELVVPTLMPSSESFDFYRKVEDNFVAKGPNGTHMFIVYAFAGPSVRAISEFPENRRLRADLARKIAAQASSALQRIHHAGFIHGGGYILPKTSLCTSNFLFRSTDDVHKWSDDEVYYQLESPETDAVQMLNGQSIGPQVPSEVTEAVDPFIFFENDLLQERIVVVDFGQSYAASEPPKDYKPRTMMNYMSPETRFEGRVGPESDVWTLGCAIFEIRAGFPLFDPFFPSDAVILTRIVGTLGRLPDPWWNVFKNRHLFEEDGRPKTNGIAVTPSIRELLQSVGTRDEILDSDGGSMFEQTETRIDGTEVDFLVDLLEKMLRYRPEDRIGVDEVVNHPWFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9R6</accession>
    <name>A0ABQ8V9R6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_468813</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="118"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4482721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="361" mass="42190" checksum="73CCEC8926C1240E" modified="2025-10-08" version="1">MMDLSQRLPQYLLPFFSLSSPTDTPANPDSFPNSQHYRTDPKDLCLVITIIAVYAILRDALRLGIFEPFARWKLSRDIQLQRKHTGKPNGNTSVSTNGNGYSKSKLIPTKAERRKLHRSVLRFAEQGWSVVYYTLQWGFGLYVYRNLPTRVLDPVDAWIGYPHVALAAPVKIYYLTQLAFYLHQMLILNAEARRKDHVQMMTHHVITVFLMWASYYYNLTRIGCLIMLLMDLCDIFLPLAKMLRYLNLPQIYPDLTFGTFMLTWFVTRHVLFPIAIKSTIFDMRRLIPFDWDPERGYYHTLGSHTMFYLCLLVLEVMQMIWFTMIVRVAWKVVTGEGATDVRSDEEGEDEDDSDDIKNKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA01</accession>
    <name>A0ABQ8VA01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_469145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4482730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="188" mass="20549" checksum="9D663E297071E5AB" modified="2025-10-08" version="1">MAPAENLKKRKIAVLGSRSVGKSSLVIQFINNEFVESYYPTIEATFAKSVKYKGAEYDCEVIDTAGQDEFSILNSKHAIGIHGYVLVYSVTSKASFDMIQIVYDKIIAFCGVTDIPCVVVGSKVDLDSRQVSPQDGEKLAQEINAAWVETSAKTNVNVGKVFELCLAEIEKQAPQTGEAPQTNRCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA12</accession>
    <name>A0ABQ8VA12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_840759</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22265">
        <property type="entry name" value="UDM1_RNF168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.970.30">
        <property type="entry name" value="eIF4G, eIF4E-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022745">
        <property type="entry name" value="eIF4G1_eIF4E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036211">
        <property type="entry name" value="eIF4G_eIF4E-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12152">
        <property type="entry name" value="eIF_4G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101489">
        <property type="entry name" value="Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="1408"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="323"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="840"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1247"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1336"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="279"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="375"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="489"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="655"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1256"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1308"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1388"/>
            <end position="1406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4483157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1539" mass="167200" checksum="8AC04F4BDB7E3DCE" modified="2025-10-08" version="1">MSKSSVAATSKIPATQLPSKSAWSKGPPQTASPRSQSPAPSNSAPAHATHSRRPSTLGQGIPIKDGVSIPRNNVGATKTGSVVSFGSIDDTSAPISSSPAATPAIKSSSEGVKSFGSVPAAVSQINGKSSVSSSTKPPLSQTSSSTSISAASTSSSSTSAPTKPKVDVRKFFQSTPQPTSDSSSPSIRPSNLPPQQPSTSNAPMGAPSYNTFVPAGMRVPPNPVATGVPSTPRSPNYPRQQISNGNGPRPPNGTNAPPGPPMQPPMGSPRLAPHPHPGQQPNVQPPQMQAPVQMGWGPYYYNMAPGMPPEQGGYMYPMPWAYNMQSQQMPPPHPQQHPHPPLSHHPSSQGPPHPSMPMSPRNPPIPLQGGPPGTPTSSHASAAPHSPHPAPLSHLSSNSISAVSSPPPTPSSATMPGSARLNNNANPFVPRPTSKIVIKSADGSEVNLENFKKGPSHQSSPSIVTSLPTPSPSGLNSPSRRAIPIVAPDSKKKREEKEREEMQAKAATLEKERKAKEEIEKKAREEERLRKEKQEAERKEKEEAKRKTKEEAERKAKEEADRLAKEEAERIAKQEAERKAKEEEEERQRLKAEEEEKARIAEEERLRQEKLEAEKQRQEEAEKKKEEEQARLLKEEEDAAAKAKAEEEEEGEVIENDKPHTDGPEAKASEIKPDEKKALRIDTARPSEPLPKRRPGPLDLSTVAGKTNIPPPLPSALATARIIEDLGRVSYPEGVQSPKIELNVNAKDGKFRYDRDFLLQFMSVCKEKPDNLPALDAIGLEPPSQPQFPIIRTQSGRGTRPGSVVRSTSVGLGAGFKGASTPFGGMGNFGTAGSASKLSSEERFQLANPGRTVSMSGAGTPFRPQGIQRTTSSGGPGSQLHTGRTRSKRGDKRPDANKAPPGAHHQQYGHAGTTYGPGGIPLEPVAPLQLSENRWDRKAIANVDQDSPEIVDRKVKSLLNKLTMEKFDSISDQIIAWANKSEKEKDGRTLIQVIRLVFEKATDEATWSEMYARLCRKMMEQISAKVQDDGIRNAEGKPIAGGNLFRKYLLNRCQEDFERGWFNKEATAAAAAAATKAKEEQALKAANTTKEEEEVALYSDEYYAAQKAKRQGLGLIKFIGELFKLQMLTERIMHECVKKLLGNVENPEEEEIESLCKLLITVGQMLDTPKARAHMNVYFDRMKELTKSTNVNSRMQFMLQDVIELRERKWQQRNAVAAPTTIAKIHEAAAKEKAAAEKDAYARQMNTSMSRTGSRRGGDRNDHQAGADGWTVTGNAPRPPAKVGDLSKFGQISKGAPMTFGPSSVFAGKKENKRESLSRTNSNANMFQMLQNVEAAEVATKTSRPPSRKPSVDLGSGGAPEPAPQRKRLNLLPRTKPVDQDSAPQQESDSEEEEEITDEPEQEMSEDEAKKKISEDTKEFFGVRSLDEAEVYFEKLPSMYHHSLVDKLVTLAIESKEADARLVGDFFERAAAKKLCSASAFEEGFLGIAEFLDDIAIDAPKATDLLAIMIKGADLGEEQRTNIASKSAENGDKLLKLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA44</accession>
    <name>A0ABQ8VA44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_469885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF411">
        <property type="entry name" value="OS02G0248440 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="500"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="436"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4482741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="653" mass="69107" checksum="984EA58E5A2143F2" modified="2025-10-08" version="1">MSNNSNLLSGLLRSISRRSQRRDADVEESEQTVRADVDMESESQQSRTADPQTAITAVANNAVNANDGNHSDSSMPALQDVSDSEDSEVDSEDEDEARRDQFMNTSQVSHSGGIVNANSEFSQHTFGRSGLHTDDDEDMPSLESTHATRSSNTRPQGTRRARVEDDVDGDSERDRRHPSQRASNNQSETSSPSPIHPAHSGHANNHVHRHIVFSNMPGGVPGVGVDAAGPLPPFPDLPGHQHHPLPLNMMAQMGFDIRTNATQAGNADVSDNGAPGNNTDSGTPEGNSNSQPGGAIPNTPNGFAAILQSFLQAAGGHPGATFTTAFNGVPVGDNLPNANAGAENGGGNSGFLGNLFTVMSGAFTFNTDLPGGIPFFNFRPAQERENPERAKVLVDGLEEVPVGLIRRLERVSPESSGCAICWEKLLEQDSEYLRREEQEQKKFEDASKTGGNTAPDASSTITQNDLQTTNPSSSIPSSTPSPSSSASKGTSINNKVPTYPRIVSLPCSHVFHSECLLPWFTRPRQTTCPTCRFNIDPDDLTRGVGIRRRAAASTAAGGRGGTETVSGEDAMPSASATTDRFGAVDPATGLPAPLSVNVQGMPFIGSVNGRSNGMPVQPPFPGVIRSGFFSHFPPGMTPTPRTASNGNTNNSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA64</accession>
    <name>A0ABQ8VA64_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide-diphospho-sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127060" evidence="1">
        <location>
            <begin position="22"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="34831" checksum="946BF0CC974D8FDE" modified="2025-10-08" version="1">MARMAFVTLLTRISYLPGVLVLDYGLKSTGSKYPLVVMVTPTLEEDARDVLTQCGIEMYSINSLVPDSSRHTVADHDARFKDTWTKLRAFGLEGFERVVLLDADMLIKRNMDELLQMPLTQDEIAAAHVCACNPMKLVHYPADWVPANCAHTAVENPLGLPPAWTPTSPRPYGQLNSGTVVLNPSPALGEAIVHFLNTENLESFAFPDQDLLTSFFKGKWKPLPWYYNALKTLRVIHPQLWRDHEIRCLHYILKDKPWEARTPIVPGPFDEVHEWWWNDFDRMASGLDSQRRNKIFSLVDTSKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA72</accession>
    <name>A0ABQ8VA72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_921932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4483122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="40203" checksum="EA1EC4636D56034F" modified="2025-10-08" version="1">MPYSVSNTASPPWIGMHIRIIKGEYKAYHGYVHHVNPSNSSISGLKIVVELSAHTSNGTNSLVTVDYDDIREFVHWRTLAEVQPLGLYQTSYNLRPDYFPPQLDVPYIPQPGPEVVSRFTTPFPTASDVTLDTFWGVQPLEEIKPQDLHWILHPAFNQKSLQVFIDPTHSLHGGHAKWVYVDNGIVSLKKQGGHTEQLELAVIQRPMVPPVRTCKSLLAIIEGNHFGELVRCIYWTRGECGEEKLWVAIATNAGTLSETLHHDVFPVSRSHTVAVKTDAEVERHGKSLILDLRSKLMEFDCICVMPRPLAIAPFLCLHVLVTTRTAPVSAIRSHTLHRSTSVPPQDIPSTIFSFPRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAN9</accession>
    <name>A0ABQ8VAN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_452639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="53" mass="6006" checksum="22CC035856BC1E7E" modified="2025-10-08" version="1">MHSLTDDTSQLFLPKQFIKQFVIPTFNDIFTCIPVFSILDKGKVTAFVQGART</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCF5</accession>
    <name>A0ABQ8VCF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_982166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="445" mass="49799" checksum="17F804E16D18D78B" modified="2025-10-08" version="1">MASDPQAGIHALPNEILCQIFIFVVTRAPGEYSASELDLSFVCSRWRAVALSLCQLWSSICILAHEDPESEGVRHLTELSLERSGNSPLDLFLNLRKDSSVMHMLYAQAHRWRHVHIITTVYHDLEDRGVKEFPLLESLSLSMNDSPPYPVSSNSRMWSNAPRLHTLSLDMTVFELEQFAVPWHQLRHLTLEYSDLDQMHKALCLCTSVVTAGFDSCTNDFSFRDPVAYTCLFLSSLTIVASHRLETLGPDITRCIYPSLSILTLISGSQEFSFSHVIVPDLTSLVIRSECHLTSLTLHGISYSSKHLMALIQATSSSLIKLDLCDVDHLAETAPIASYLQTPGHLLPHLKEFGIRFPASRRDFAIDREKIGLVLGMIESRCSSSALGARTDSRAMCVLPGKRDTSVGEVLERLHLGRLWSTRVPSEFEKRLRALEDNGLKITAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCR1</accession>
    <name>A0ABQ8VCR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_896130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1298"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="422"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="604"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="801"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1411"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1552"/>
            <end position="1638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="811"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="843"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="866"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="919"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1134"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1189"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1443"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1552"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1565"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1591"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1627"/>
            <end position="1638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4488593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1638" mass="177580" checksum="1AC20B47C7404DA2" modified="2025-10-08" version="1">MATQNLYDSAGDMRSHLQSLLDAKEKQLQQAGTLGQRVLAQQMELEERIRQLQELDAGKADEEDLDIEAKEKYQELAESLIAWDAENAQLSSAFGKSSVSPSIPVAQLPREEPERSKASASSSAAQSRRAKNAAHRADDVEFAFEIGSGLLNEVRRLQSLLGERDKAIQDMKEEKDDLEASVESLRKALKQQEQSADKYKEENWNLEVTLQDLRTQLSNAQSTNSRLDSEQKRLTKLLAASRDTSEQFKNETSQLQGALEELTNKHETDIALARKHAAGLARDKSDLQQTIDTLKTEVARAGRRLPRFGSPLTPNGAEPNDFLTPGGFSNPGDEVFSNVASTNRRNKMSELGAYDDAFGDEFADSPEGSPLPGSPFRSANHPLNEIEVLQQRLAHAQRQILTLKGTLQREKKEKLDLRRKYEVQGPEEEEDMDMEEEEVGDDTVGPNNTLNPVSGKRRGLMTFKVGVGQGIRGTGRSRGRGRGGITLTERLNFAAHDRDDEDRFSLERDTSMPAVPDMPVHFTDEDGFDVLEGEDEDQVPDQMGFQASPSPAPSNRTSVGSITSVEGMDPAFANVLRRTPSTSSVISVQANGSPLRTSLLRRSTRGRGTIGRRTRGGAAWYDGRPPSLVDQPEDLARALGSSIGASPVSIKGDGSGIGIMEELGAEIIETAEFGCQTEPEPIIIPVTAPSLPQKLMSEASVQHEPEPEPLIIPVPAPSVPQKLMSEASVQHEPEPESVLELSPLPAPDLVEASMQTAPEPVVDRDEVGVQHFPPLVSMSTSTDPPPTKSDVEVEARMEDAIRERRDTLVPGDVSIGSSVGDSTIKNAPGRAFLSSSAVGHGDEIDDGEETETGPDTEIDTDDYEDATQSIIPSTASASRDDFHSMMTMTDSEVSDSDDDGESIKASRLPARRPHAPSLFRTSSFYETPAGSSSEARVITSPTLYASKSVEVDVLPELPNIAPKPEVKEMSTQTDDWVPSVQAPVGLSPAGSSASSSGSPALYRVGSSSKQQFQFIPPVPLQAPYSAPVSVPTPSPSANVFKETPTGFATIVSNTRSSHDRRQSMDSVVSSVIDDVANIGTRSRIPSTLLVDKTRPPMMSLPPPPRAPPPPGSMPPPSFIPERRIPTNSTSSSDAPPPRPSSPPPPELIQRATTPTFGSVLSVPGGKGSGFALRQHGSSMPPSQAGLRQPPSTSSFRSAANATAYHQHGAHVIPSLRGERVGVSTTSLASDRSLASPRSSLSSDHHLYLNRSQHAFHNQNVNPNATITPNKFALSGDPLTGRTPPMDPTDPAVIHAITQTMIGEFLYKYTRRALGKGYGTARHKRFFWVHPYTKTLYWSSADPNSTNVAESSAKSAYIEGVRQVLDPNPMPPGLYQYSVVVSTPQREMKFTAPTKDRHEIWLNSLKYLLARHGPSQSAPGNATVVPDSPTSGEEFLPEDDRHLTVNSSPRSQRTGRSLRSDTPFNTTPRGKRSRSQMSMGGSIGRRAGTPAAEYLRWNGPESPCSPSKSFVDVPAQEDEDDLDFELHGDSFSDDGFEGLENVRACCDGRHTVGHSGKHHHHHHHHHESDSQNGDHNHTGSSNNGPIRPVSPSAWSFRSRTGSANSHEGGSASLFSWGRGRTEDGKSKFGSRRSTKTVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCV1</accession>
    <name>A0ABQ8VCV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_959302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4482638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="351" mass="38670" checksum="412DB8067E88E213" modified="2025-10-08" version="1">MSDTASESDSITHIDDVHALLAVLTQDEFNSLVNAATYIGTQRDGELSGTPTSILSRCHVEVGPDGSFGMYTDNGNQRIEIAIGIQPRSNGAYKNGPDGNAVISSYQDPALCPIGVTIEKTESGQLVKNAMLDGKEWRCLIWNNNFEPKKERSWEWSISGPPATEESRAWATVVFKSIETKFKETAKNEGIQFQPNTSGPADQMFLFARRSVLVTNATPLDEGRGSEYPDPYNILTAIGPDRDFKFNRLPEVLVTDHKEETDVPMSFHDLHLLGKNIALQVFVTPWAYKHRGKLSWDFRLICVKVLGKKEASLAVSPSKAVLKRKAVYIGNIESTAKKQKASGSSLESSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDG4</accession>
    <name>A0ABQ8VDG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FMR1-interacting protein 1 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_982441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039136">
        <property type="entry name" value="NUFIP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMR1-interacting protein 1 conserved" evidence="2">
        <location>
            <begin position="168"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="440" mass="48622" checksum="7A7F72B827CA6A85" modified="2025-10-08" version="1" fragment="single">MDPPASLPSRPGASQNNIIPSSQAAAFVLRSALTNPYSQTYSSHYAQAYMHQYNGMPFTNAQGYTMSSTYDPNAYVNNNQNQYFTQSSAGPSFSRPQNQSSGGIKIQNFNQANSAWYQAGHERCTYRGCRFTGSAKCVEIHMMDRHLIYPPGWDPRKKKDWDADPSLKGKPILIQGTNLTLDTPDAIDAWVEERKKRWPSSTLIAEKKRKFEQASARGELSVESLGLFSKKKRRVQDPYEGNERNHHARGGRARGRGNDWTPRGSSDSGWRGRGARGRGRGSSFGSRGDDTIDRAPVLECAVSPQVQIHEPLKEEKDKDDSASDSDSEPEILSSKLPPVPEKQVKVSEISSPVPTQSKPKMVAKIPRPQPKKPPPNPFAPRTSLLRNLLLPEIRMTVSNLSQAIRFLVDNDFLDGVELKPGDADAVPIQVVGSVSTSGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG86</accession>
    <name>A0ABQ8VG86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_769240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27721" checksum="377F5B46332AFF29" modified="2025-10-08" version="1">MFSDYDWAIIRIATNWALAAAFSNIYLTWRSVALIDQILFKALWTVDYVETLPTEIHSIWKQNKTGTSILFLINRYIFILYIIFKGVECFPGHGTNKQCLTIHVISQLCQSVAMLTTNVLLAFRVYAIFNKNKGILGIAFGFILSRFFLDILDIPLSFGASATGTPFHSFSRCGIEVTKANEFDQDFIFSRIQVALPFHALGYDIFIFVLTAVKTIHQAMAMHRLGQSSITKLIILDGKYCMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGP8</accession>
    <name>A0ABQ8VGP8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_866847</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF7">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="408" mass="45352" checksum="9B4713958A8A3AD8" modified="2025-10-08" version="1">MSKIEKDGLTESTLAYTPHGLIMAKILKNSVEYFKFEHEVSSYMKKFHIPHPEDAENMSLIDYYNNCAICCTKPPNERCTTVLQVQFLNQLELEKRFPGLIHGGVTSVPDPVQIGAGTMYDYKDLRLHKVCEDQQKIASCGQHRWIITTGDPTHPRQKEDKVEMVLFDAFSNSCLKRMIFNFNHSTEVAALQRQGRVSGDMIPFGTRVPKGGAPADGLRPFEGINATTTTGVDEFFAQAPRIIEITMVVTSVEGAPNANAKEEAYLHTHPSWALLLQHTFVYARVSPLQKELILTSLKNLGYITLVAGDGTNDVGALKQAHIGVAILDGTPEDPQKIAEQQKVERVKQVYESQLKISARFHQPPPPVPVGAAEGGGVPDGGEEEEFRWRNSTWLVSQTNGEDEVPIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH17</accession>
    <name>A0ABQ8VH17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RhoGAP-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_830372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13277">
        <property type="entry name" value="PH_Bem3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="5">
        <location>
            <begin position="624"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="745"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="6">
        <location>
            <begin position="1120"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="129"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="368"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="863"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1336"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="457"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="517"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="878"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="906"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="935"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="962"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1039"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1348"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1369"/>
            <end position="1384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1448" mass="157331" checksum="D5ED98AFA0B33C92" modified="2025-10-08" version="1">MSARSPSREKDNRQPFPHTSSPHRQTTLPTASSSTTNLPASINPTPHTIESILALHGSASDPQLAALDQAVSERNVLSSQNSQLWKLIEKQRSGYNQIMKELERVRNERDAYKARLAAATGGPIVSEKRHLSRERVQKQSIDSVVTDGGMSSNNGDHNPRQNITRFYSDEQVPPRTNSHGLHSARSHEPLANSPSASVSSSSLVSSTASTNASLHSSQPMTARLAPLTVPPRSDLLPELSATQETPPQSFNNATPKYSHFAHGYNDSIISSISYSSSSNSHSTSTKPSVYPRKSSFTESISSVSTNGVDGVSGSAYSGIATGGRYDFSSQNTPQTAPAEYLSNNSMYTPVTPHGQGTLSTPQIITSISIPNAPDRDQHTSPISQKASNNLTALSPAIRHPLSRESRISLPDEAKQYIANMGESPVPSPRVEMFNKTSSSHSSVPVSPVRGKDREFLDMEEEPDDDNDDGDEEDDESGEEPDEEYEVVDSSSAAPNSAPAPSPSASAESSQDRLPNQSGSSSTSFSGPLSQAPARSSSNRQYVSINDFPLSPSTMSPHHVEARAEAAYQRQLIGDTSPQRSNDDLRPQRLEAQNVPATQMNATASPAGFFRALPLLSTDLPHTKIYVSHSFVRPNDRGKEVLSFIVYVNPGKGKDGWKVEKMYSDVINLDQRVRGSVGKSVGRKISTLPEGKLWKDHAPAKADQRKAVLETYLQTLINLPVKNNDEVIAFFTTDIVKDTMQPVMQVGHKEGYLTKRGKNFGGWKTRYFVLQGPVLEYFDARGGTHLGSITVTGAQIGRQQRNNTTTSTDEEKEYRHAFLIVEAKKGPGGNHPRHVLCAESDAERDSWVEILVRYFTGTYSEEPVAYAPSSAPPPPPPQYVNSTAQPTPSVPRTSISTDPPRKPSRGFSKDDIGAEKRAIPLSQLPQDATNAKLFSRPSQDDYNYSSPSKSIPAPADPRTTERSQPGQPSSLPDSSPLSNPPPFLDPGQRANSEMGHYPEIQTVRAQQQRQSPELYRQRGDLSKQSQVSSPIGPLPTERVPSPEKMEKVKISAPMNGAPIPAGYKFGKDNPPEPSLTPSSSDRREKAKSRSFWGFARPGGSGGGDKNITPSSTFMPRAVFGVNLEESLDVAQIANLPAIVFRCIQYLESKKADQEEGIYRLSGSSAVIKSLKDRFNAEGDVDLLASDEYWDPHAIAGLLKSFLRELPSSILTRELHMRFLSVIDFVDPQERIKELSQLIASLPITNYSLLRALTAHLILIVQNSAVNKMTMRNVGIVFSPTLGIPAGVFSLMLGEFNRVFNVDAGRSPLESNEDLELEPDRRNSLQYSEAAADKLLGLSGRSLSTPAEETQSDTDEYSINEDSGTEPEVTIESSPDSPVGGTQQDLTPPDTPLAHSKNGRASNLAAGRGLNISVSDRGHRYSRMMGLPTSPRPPPSPGGHSASPSPLPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH58</accession>
    <name>A0ABQ8VH58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Membrane bound O-acyl transferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_919773</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="9">
        <location>
            <begin position="223"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4492471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="396" mass="44630" checksum="D243DE3BF33CC3DA" modified="2025-10-08" version="1">MSQELLHPTLESTPSFTLPLLYLLFAIGLSFRSRILRASFLAIILAISYRTVFYTSTSEAPMNYLYATCSFSLFFSALDFLAITDPYTELRRIGQVESTSSMPFFSRFMWCWKLILTPRGIGWTHEPTNVIPPRPKPQSRISFIISQLPSTIILIFVADASNLLLRSHPGFLPGGPSIADVGPLMRFVNVFLFGTSSFYALQLQYKLLSIMVTAVGLSHPENWPNLMGSWSDAYTIRRLWGRTWHQIMRRWVSAAGNLVAQKLLRLTPGTNLSAYTKLFIAFLISGIIHQMGDYSLQHRDFWAGGSLTFFLLQAAIIMVEDGVIALGKKAGIQDRKRIRLLGYVWTASWFALCLPIWVDPYFHDGMASGKLFSPIGGLWKGDWTGASLKISLPLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHD0</accession>
    <name>A0ABQ8VHD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_763863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="229"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="305"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="418" mass="46757" checksum="953CCA9A633EC06C" modified="2025-10-08" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLGESHSIVGFPIVSNIHLHSASSSWWELISLGHIDSVTFVPPCIHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIS2</accession>
    <name>A0ABQ8VIS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Laccase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_919502</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13903">
        <property type="entry name" value="CuRO_3_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046067915" evidence="7">
        <location>
            <begin position="19"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="62"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="176"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="381"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4493284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="533" mass="57852" checksum="83DEAA4C1A4029B8" modified="2025-10-08" version="1">MLPFVSLLAAELVCLVYGAEVIRDTTTYGQTVSENLFIVNKQLAPDGFQRSTVLAGLTPSTGSFPGPLISGNKGVRFNLNVTDQLTDPSMVRSTTVHWHGLFQKTTNYADGVAFVSQCPIAANHSFLYDFQVPDQAGTFWYHSHISVQYCDGLRGPLVIYDPQDPQAYLYDVDDETTVLTIADWFHNTSTELIAAAVAPLADATLINGKGRYLGGPAVPLAVINVQQGKRYRFRMISIACDAYHNFSIDGHRLTVIEVDGENHEPATVDNIQIFPGQRYSFVLTATQPVNNYWVRALSSSGVGSSGFTGGLNSGILRYQGAPDADPTTTNSTGVVLTESMLHPLENPGAPGLPFPGGADEVLNLTLGFNLPATFFMNDTQYIPPTVPVLLQILSGAQSPQDLLPPGSVYTLPINKTIEINFFGNATPGGPHPFHLHGHSFDVVRSADNTTYNYENPVRRDVTSVAIGNQTTIRFVTDNPGPWFLHCHIDLHLEFGLAVVMAEAPSLVKATDVTTPAWDELCPIYDSLTPAQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJB0</accession>
    <name>A0ABQ8VJB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_766326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="112" mass="12882" checksum="81A36FB48B016AF1" modified="2025-10-08" version="1" fragment="single">MYTALSRSYFAATTIILQGYDSRKITGGASGQLRREYRELEILDEITRLRYEGMLDCTVVGNTRNLLIESFLAWKGKNFVPPLIHSAIKWSTKDPYVPQQETLPPWSLIDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJE0</accession>
    <name>A0ABQ8VJE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_918582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="375"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="632" mass="70150" checksum="B3E00DD251A58D3D" modified="2025-10-08" version="1">MDHNMDDAPAIHQSAMPAAQTANDSEVSTTLIPRRHPRLRPINCTMDDTPRTNDSKTSPPPPLPPTPMNRRRKLSSSSSEDDQSSSQVDEIYKKPQKVTDFKVRVVERVVEREVVPAHVTQQLAERDEWIVQLQCELEAEKTGKATSKDDSNVPQSSQAVSFTEVERRKLRGDIIDKARTIESLTNLNEKLQHCLVDSRRDLAALDEELKNTKQNSDSLTEELKESKETHSSASLEAANQLQKRDEEIERLQKELEHHRRIAVQDSTAKDPKTESLLTKLRNAESGIEEKMGQLSQFKRQVKYLEGNIATNDIHSQELNAAMQALKTGNAQLEAAVATAEKKLGDQYNVQNAEILDLKQKVHDLDASIVAKDLFSQNLSSDIKALETENANLNAVAKAAQNEFEERFATKEMQASALRNTIQALEEEKRKLEETAALEKPEVEADREAFKNLRETTEVLEQTLKELQDNLASKNSLINSLNTDLQRLETEKSKIAATAAAADKGHFHCWEDSIPVEGAVQESPRRIRLVVPPGRSMAASTSTPALPRAIPSSMEVSVRDEPMQGPSGLVQLAAAAEVQSGVVQRFVSPSPVTSRIKGTGFDPLPSNMPPTSHSSLVPHCKTWVRIGLRVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJX3</accession>
    <name>A0ABQ8VJX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_918270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024119">
        <property type="entry name" value="TF_DEAF-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237">
        <property type="entry name" value="DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237:SF14">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="422"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="604" mass="68763" checksum="B1909F34C1ABE0F1" modified="2025-10-08" version="1">MSYEQLLLEVVQYIEYRQPNATLSNADHVLVTLFDFIPGSFRRGATFRRAANKLYRKTMDEPLAIINSFAFCGAHGCEYCHECYADHRLTNNHQIMDQLCAAFPALTEDHFLDRQPISYVFDKAVARTSGKEPEYECKEHHILDCSTCFDWAALAVEDMKRQAQSKNTKVIAVDITRKEKLQYLYSMGVNLPLTTRLLDDAIEKKFRSAIDASQSFATLIAKLPFDPSTLPLWSNKTSKTTLLKTVSRGNFEEAFANIRARREGKEITWPLFENTFMDARQTIMGLADGIDKGVKTVLIQDKDTKYAICLRVVEVRMLNEETPVMVVLCRRGTRDAPALETIRWAQESISNKKLSLLKVKATPEEQKLLLTVLNMNARRLPPAYSVKRNSSGSEATFALSFLLPLGPINQKDIGKLTHHTGCVVCGKKTVSKCSRCLSIEYCGVECQRIHWKEHKPTCNSLRGGDWVQFTFSVQPPEMRLAAARGEKISMMTWNNMSRATRDNMKIDPCDDEPALPPNMHSQNPFLIKMQRGLVGFMPPIMIYDRTRSIQVYLCHDVDLEGHEKTMAQMHTGQKGQKIYRWAKRTGDDKLSVCLNKAPPQDPQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJZ8</accession>
    <name>A0ABQ8VJZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_367119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="23108" checksum="F3F2C09BDC05242D" modified="2025-10-08" version="1">MTEGTITRWLKKEGEAFSAGDVLLQIESDNYATLDVQAEMAGVLGKILIPDGTSNVPVEKVLAVVTRDAQELTRLRPPPPRLRPIPPPLSRLDVPPTPVRMSCSPYPEIPTPISATSFYQLPSPALPESPTSTPALRRPSLHHHHPLSNASRLELSQRLCESESTVGCEASYSRVVDTQVEVAGLDLRRKILASFSKGPGESNGALEYLNGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK16</accession>
    <name>A0ABQ8VK16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_825747</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF2">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="155"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="272"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4496748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="443" mass="48523" checksum="E75312C61DC8072E" modified="2025-10-08" version="1">MTSTLPPLVQAVAGAIGSASANTLTYPLDLVTTRVQLSSPADTGINANVGKQKEREQENALGSNSPHVFTKQLQNSTRFKAVRILRSIIQSDGVGALYDGLFTDTASTLISNFFYFYIYSFLRKLLIRRIAGSQLSSASPLKESSSTRPLPSIKLAVWQDLALGFMSGVASRAVSMPLSIITLRLQTGRHEDSDESGMVKQEPEARENAVIQTVKKIYEEQGFSGFWRGFNTSILLSLNPSITLAFFQLFRRLLALIRRRHSNSQPALIVDPTPGEAFFGGAISNSIAVALLYPLILSKTRLQASRSKSTAFGSSESQSASRPKTLGAVMLDAYHGRYHHGTSSTSSTSDKQVRRASGINSLYQGLEMQILKGFLNQGVTFLVKGRIEQLLIGAYMKHKLLGASKLSIIPNLPLPSISMPFSNDPHRSLEAWNIVEHVGRRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK95</accession>
    <name>A0ABQ8VK95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_824808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046497066" evidence="1">
        <location>
            <begin position="28"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="26112" checksum="48DC4332BC571453" modified="2025-10-08" version="1">MPCFRATLFLHLFGMCIISSIVLSVVASPIFHDGALLVSRADNDSDSEASSIAYHPAQDGARWEHNVDGQIYWHENPVEANPNVLRDSGKPNNEVKDLAIVIYRSKRRNIPESEKEYRVCVGMRCLRANKDPKAPSDLLSDVIIGRGTLQELKNVGKISFDDIEHKRQILAVFVKGQRHYFEDNSNPTNWDYIAALLRELRRESFGGPPLANQEEIEQYMKEEAKKNLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKE1</accession>
    <name>A0ABQ8VKE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="584" mass="63947" checksum="60121016C9BA0911" modified="2025-10-08" version="1">MAEAAHVQCAAAVRLLSILVKGLPDHVPLASTESRISEIFKKVPEPLPTADPDEHWTTFNRHMDLLYGNDVRGADGKLLNITRGPFGLDLVVGYIQSAVNAGHLLWEAASPKFARLVTGVQNISKDPPVRAKTPPRMTIEEVHDEEAPAPTIQKSQHMKAKTSTSKESVLGKSSAKRKKTTASGVDVWADTLSADDAEYILPKHSRIQEDSESEVFDSNNEEIISATERGKELKERSKKRAARGAEQRDTKTTQLGKNKVLSINSGPESNGQSAQHKVDTEEAREQAKGARRGPSNASMQHFHEPVAVMDKKKGARWEFKCRYCECIERTVKGPKVSFDDEGKLPKLNNLATHSNECRGKSKPQERSDEGNRMEQSTAEGLNLKCSADLIRNYLKDGELNPEALTTKRGFLRLFAAWILDEDLPWTTGEAPSLCLFFNHSTSTLPEAMEEDQQFEYSTLYTGDGQPVQVLTPCRGQPPVVAPARGWSITRIDSPILQAIARRTGKQPQCRAASNSPHDPPPHFDLDAGDHDDQDPPVDPDDPGADNNHDNLDDHSGGLPRGEPGDLSGPGGPSGSRSPNSPDIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKK0</accession>
    <name>A0ABQ8VKK0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_760520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="46491" checksum="4DCA5AC49A7CC49A" modified="2025-10-08" version="1">MELSLEAYRIIVNNVRSRVDLATLCLVSKGFRRVAERALYNTLFMHETERTERICKTLVGQPRVAELVEALTIAIEELVPTTSSSARRARPETEETLWPAISNALKKMSRLRHLSIVIDGSFSSPYSGRLAWILADCPFRLKSFHSDMRWDENLVRFLNVQDEIEDLYIGDYDEGEEGPGEVEESTGLDEKTPVTTRPSGPVGPRASHNSLLTLSPTALPHLYTLECTFSEAAIAIVPGRPVSRLKTCFSRTDPEGKRAEMKEGLTGGGGRGGWYALDIADAEYEEGFARDLLRAVVNLTLGTLRYLGTLVLPVGGRERLLFYGLLMQLRYLCCVELEISGWNPSPTVVGPVAFRALGNELRLYCPGVVKIVFVSMNAGEGEDIGERTTVEWITGEGVARVEREVMNGMSGTEGIWRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLF6</accession>
    <name>A0ABQ8VLF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_823691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="35370" checksum="66B86D3223EF2950" modified="2025-10-08" version="1">MALPSAVLHISNHILDQLSKAVIRPLFVALQGPQGSGKSFLANLVRSHLSAPPHALNVVVLSIDDLYLTHEELVTLAQRNPDNPLWRGRGQPGTHDVELGSKVLRSLKEGKNGIELPRFDKSLFDGEGDRLHLDGTGTIVDSPVDVFIMEGWFMGFYPVSLQELQTKWDGIWAQERQLLGLNDAVVGTKNDIADVNEALKGYMEIWEFFDTIVKIEAASSPSSVSSLSMIYKWRLEQEHDMKARNGGKGMTDEAVKLFVDRYIPGYIFFGDGIFRGYVGCLGAEKKDMTRFAAPRWLGRSLRIGVNEKREVVAVEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMG6</accession>
    <name>A0ABQ8VMG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_894541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046810705" evidence="3">
        <location>
            <begin position="19"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="113"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="572" mass="63749" checksum="0BF792AFFE670BF6" modified="2025-10-08" version="1">MWPTSLSSSLYLVLQGLGFLNYENLPDSNLPFCRAFPGDESWPTEDIWNALNASIDGRLIKTVPVGSPCHDPHYDKNACEYVQQNWHQTEMHISHPSSIMDAVFLNKSCDPFTPRESPCYVGSYVQYTVNVSEPIHVMKTVEFSKKHNIRFVVKNTGHDYMGRSTGAGAISVWMHHLKEKEWFDRYSSPGYTGPALKVQAGVQGAEVNAEATKHGHLIVAGECPSVGFAGGYIQGGGHSTLSSVLGMAADHTLAFEVITTTGEFVTASPTKNSDLYWALSGGGGGTYGVVWSVTVKAHPDIPVTKARLFFSSEEISRDTYWEAITAYQQIIPSILDTGSFLDSTYDVNKFRMDPLIGPNVSSSTVMSVLGPWLSTLDSLGIKYEFNLTEHAKYVEAVAGYDNFDIMGYQLGGRLLPRTLFETTEGFSEFMQTIRDIVEGGAYVWDIGLRPSWEAGGYSDNAIHPEWRKAERMYNPVLFFDDDDPLERIWEDQRRISALFDEPLRRLSASGGAYANEADPFAPDWKAAFYGEHYDRLLSIKDKWDPEQLLYGTIAVGGDRWEVIEDGRLCKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNY1</accession>
    <name>A0ABQ8VNY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_758488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="25478" checksum="FB81EA83F5E50EC8" modified="2025-10-08" version="1">MNEVRGMNRGSYIYGRSVHNIRIERLWVDVTRGFGKKWKDLFHLLETRYGLNVDNERHLWLLHHLFLHRTQHDIDVWIGSWNHHTISSRTQTYQTPTVMFQQGVIQHGFQGLFPESVNESREEVYAAYGVDWDDIENRNIVAHHHQHNPTSDNSRNFFDADTPEEMSHVEVPEVQDSLSIEGVSRLDNSLSALSYFSQGDISSLTQIWVEASNFLCSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP10</accession>
    <name>A0ABQ8VP10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lysine decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_917034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="23802" checksum="7F51B58421D388D2" modified="2025-10-08" version="1">MSVALTTQSGPLAPASVCVYCAASPGNIPAHRAAAVSVGAALARAGRTLIYGGSSKGLMGIVSSSCLNAGGDVTGIIPYAMAATGGEGTGDGFEQKGKLKTIIVKSMHERKMKMAILAEGGFVALPGGYGTLEEIFEVTTWSQLGIHSKPVILLNVEGYFNPLRMFIQDAVAAGYIRQQYVELITFVDAPSDCSQESFDWGLAMLQSLSTWNSAKEGLFQWARTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP53</accession>
    <name>A0ABQ8VP53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_162495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="130"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="23894" checksum="CDCDA25622144B95" modified="2025-10-08" version="1">MSTFHQLMTLDQSSTNFTQPPIPTAGPATEPDGPRSFAFVPTLGILVPHPPPPVIQVQRQDTLGQDPANTVVDASGSIVGNFNTGAGANHYPSSAGVPRLPPILQVEKQQVTTSATQLASASRRRNEANFACPVPGCGSTFTRRFNLRGHLRSHTEERPFVCEWPGCNKGFARQHDCKRHQALHTSKPQSNVCQGCKKTFSRLDALNYALMAGQNVAPNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPK2</accession>
    <name>A0ABQ8VPK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleophile aminohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_147468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04701">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF43">
        <property type="entry name" value="ASPARAGINASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="401" mass="42989" checksum="04251B1A1DECDDA9" modified="2025-10-08" version="1">MGCCTNSTTYVVTRYPFVIVDCVSAAVEVGIFTRKLLSFFTLMNGSEKEEQPLLSRSAGRVKSKYVLIIHGGAGTMSGKKSTDAQLKAYHDALCVALKAGHEVLKSEGEAMDAAVAAVVALEDNILFNAGKGAVFNTAGKNELEASIMLSKPPASHPYIPSSRRGFGLSLLTHIRNPSRLAQKLYLTLSAAPHVFLSGNNAENIAESLGMILVDPSYFFSEARWKEHRRGLGLPDMPYPPGSHGSGGEIEEILFPESLGSLDMYPTGTVGAVALDVRGCICAVTSTGGRTNKLVGRIGDTPVMSAGYWAEEWEIKSGWLKKAWNTVTGKENPSKMAVGISGTGDGDYFIRQATASTIARRVQLLDIEGNIATPLNCEGMYRGLIREDGVAKTAIFEDEALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPK3</accession>
    <name>A0ABQ8VPK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PiggyBac transposable element-derived protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_823415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="43340" checksum="6754A1108B9B8C0E" modified="2025-10-08" version="1">MGNKNNARNKQSGRRKNKNPTQEIEEDQLSSDESLTPDAPLRPPRPTPKPYHRGIPAYDNACHSASGAEIDDTAAARLLMSFSGVSPSQSQATPARTHPTSELHAPFTCHKGSMPGAKSQTIRTPGHPQSARQTSRLTVDEEVFSRVMHIPHDEMIAQRNYRDNMEEEDEEGVLLVPLRKSKVKKTSQVEITSDSENNASSGSDDDEEPWNAHMKAVEQFDIPFEVPYRNSKRNLSGITSHTDFNTFLLELAMAMDMRMSLLRNISYLPSYRPKGKASEGPNDIRLENESDWISLIRNVKGYLNTRTARQVKQVWSITILDKTGVDSASAKENTSKVTKTPASTSEGSVVSTSDATLLVSLRKETKCTACQSPCYVLNNGDHYRYTDGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPW1</accession>
    <name>A0ABQ8VPW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="23870" checksum="67A92B6832AE55E4" modified="2025-10-08" version="1">MPLLVEPRPDIPTTKIAITSKKTIMSFQQRQGLYVDSCRENARNPQKAAGRVHLEMPEHPFIRDEGLYWQESPKSTSTGNFRGEPCIHSDDEETLPQSDVCPPSVSTSAVFSEADPTITSLTRDFWELQIEVVDPRNFTGRILCLSTTLSGVFGPEARVCTSLYAKSKSLALTLAVELPGGTAEGFDAGDLLSSSENAKRKGTPGPTTLESPQLLCPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQB1</accession>
    <name>A0ABQ8VQB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_757046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010895">
        <property type="entry name" value="CHRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF1">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50933">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045357876" evidence="1">
        <location>
            <begin position="19"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="CHRD" evidence="2">
        <location>
            <begin position="257"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="297" mass="31130" checksum="1C9EE3D571017998" modified="2025-10-08" version="1">MKTTTFSTLAALVYAATAFVTPQVRDSSSSSSIDDTDVLNYALTLEYLESNFYAGALNNFTQDDFINDGLPVWARGRFEQIAAHEKAHVVLLNNALGSNATQACTYDFPYTSPSSFAALSQVLEGVGVSAYAGAAQYITNSQYLTTAAAILSTEARHAAWVAGPVNKENPWANPFDTPLSLSSVYTLAAQFITGCPSTNPSLPVKAFPALILDNAAPGQATNVSADGVNAEGQYVAFFSGLSTTFVEVQNGQVVVPNNSMSYAVLSSSNTTADDSTISAGVAILSFPFNSNGTLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQE2</accession>
    <name>A0ABQ8VQE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_756648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="236" mass="26873" checksum="A9ED26C00B192EDA" modified="2025-10-08" version="1" fragment="single">ELALSRQQVSGIEGPFAYLSRGAVFSALIFRGITFNTDALHETGHPGLFDTFEAWSQFKSQYVHGGEWFICNPHAYGTTKGRVLGNDQRFWTSSQVLYEKLTRSNISFIGIWKFITYGKDNQKRKLFPSFGNLSAYLLTVDFVYAGCIPWPMLEEVARAIAELSKGALHGLQKMGLISKDHFKKEDVEETFKALYSYLDQDEKFAIVKKAVVFDLFMVEHALCKVSKDRVFENHSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQJ3</accession>
    <name>A0ABQ8VQJ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GS catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_758394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF12">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="4">
        <location>
            <begin position="121"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="482" mass="53442" checksum="9A9C93123952BB30" modified="2025-10-08" version="1">MISTKDAPKTLQDLETLLKNDNKVKVAVDGVLRGKFMSKEKFLSAASSDGFGFCSVIFGWDIHDTVYSRELLISNKANGYRDILASIDLSTYRRIPWENNVPFFLVSFLDPDTKEPLVVDPRGILKITSDRAAVSHRSCYAGVEYEYFNFKETPLSLAEKKFQNLTPLTPGMHGYSLLRTQLNNEYFHSIFDEASKFGVDIEGHHTETGPGVLETALAYTNALRMADNAILFKFLTKSIGMRHGVLPTFMAKPWGNLPGCSGHTHVSLRDDSGKNIFAVSEAELSTGRPGAANDDVKFLSEEAEHFLAGILDGIADGIQPQLVPTINGYKRLVGGEAFWAPNAITYGYDSRAASIRIISPPSVPSAATRLEVRVPGADMNPYFTISAIFLLGLRGIEKKLKLSTPPMNKLTADDKKNGTIKMLPTSLEAATERMMRPESIARENSMFGDVFVEHFGGTREHEVKVWNEAVTNWEVERYIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQM5</accession>
    <name>A0ABQ8VQM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNI-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_817374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056451">
        <property type="entry name" value="Znf_Tbcl_Rhp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23550">
        <property type="entry name" value="zf_Tbcl_Rhp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair protein rhp7 treble clef" evidence="2">
        <location>
            <begin position="133"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="585" mass="64267" checksum="C053F7AC77940A59" modified="2025-10-08" version="1">MSSRRNNVRGPTSALTDFLREQNITPTTVATRVATQNQPAAGSSNSAQIPDSAEEPVLLRRNQRRNRVTTRDEYDSDGLDEPEAPATKKKKVSANKAKGKKTGKKDDEDDYEDDDDPYTALSKMGARARPANGSIERCAECEKEFSVSQYTIAATGSGFLCHTCAKKLGNDPFKKPTAPRKRMKAADKRNIVHFEKPRFPTLVSICINIISTHIDDIEAFGEIGTLNMDAISKAISRKRSLNSENVHLFYGPGNTSLTLYDATKLSSTALITLGHLNPNLTKLHLNFCGLISDEVMNSWCSSLPNLVHLQLLGPFLVRVPAWIAFFESHSQLQSFLITQSPRFDLECLQSLIRTSAKTLTRLGLREVGLLSDDFLGPIGLLSGQLSYLDISEPSQSCSNEAVNTLLGAVGSTLTDLNLSGHIELTDDVLQYGILPNITSLQHLTLSNLPLLTDEGVTLFFSQWPNPPLTAVTFSRNPKLSTNSLVELLNHSGEGLRLLDVNGWKDVSATALANIATQARDLGKIDLGWCREVDDFIVKSILDNCKNRLTEVKVWGCNKVQGKWVTSGTKTKAKIFGIERAHTSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQU7</accession>
    <name>A0ABQ8VQU7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Winged helix-turn helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025959">
        <property type="entry name" value="Winged_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13592">
        <property type="entry name" value="HTH_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Winged helix-turn helix" evidence="1">
        <location>
            <begin position="94"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="165" mass="18973" checksum="7D8D76EFA4BF80FF" modified="2025-10-08" version="1">MTRGHPFSDDLRQVLIYMGTRCTFLEVMAQTGVPRSTLRALFSEYKKNRHVLCTKESAYEMRGRKRKLTTANVGVLILAKFLTGNIRQRNDLYLDELQDLVSSRLGISVDDSTIWRTLHRQGFTMKKGMGIERAESRKEVFLCSWPQIFTSTNTLHEGNGLFQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR10</accession>
    <name>A0ABQ8VR10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="23532" checksum="055B80F3588B3669" modified="2025-10-08" version="1">MELGSDIISELISASNAASPPGTVEKISRTSKRRQHENDPSDGEHLPSSALGDHFSRMVDLPSITSITGSSYSSGMSYSSGIPASAREIPLSSEALAPEGMLNVTPDLNSSEGLPLRTEDLGKLPVRFLPSSYANDEAQAPAYLIPVLSFQHSGFDSQANDPLVSNLGIPFGIDDCFWGPGAAPAHAALAMFNNTPGGDQWDDWGTYIANVDELLRSLDPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRA7</accession>
    <name>A0ABQ8VRA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinesin motor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_915985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF12">
        <property type="entry name" value="KINESIN FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="695"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="567"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="801"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="567"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="600"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="622"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="967" mass="108588" checksum="DEB69BF33CF86221" modified="2025-10-08" version="1">MTLLFPKHCTGSIDAAEVFSQIHALSLLLIANSKDEDQDETVRPEEYPLELDHECILASERVEEARSRYDILKEIEFSHFDTLNFALPFYAYALGNPCECLDHLKKVPDVTHVQNHIPLPVTLRHRRNRMKNIYCRYQRRSRLGNNGNYPQHMLTRHVPRKALSYRSSKGPRNICGVLSPSHNRENLTNINFRPDSHLESDSFWTWLEDYSSCSVYWPSNFRTSHRSTTSLIYLRALVLRHGAKTPEPAPVGTGRKSPQWRNTARSVIQQYRAILNVSTSLPKAGERNHKVEDFTEQCVAVWEASGDVGEYGGWFLDVRWCAMRLTFNSSTIQRHLTRLLYVSGDNLLGGRTFNLYVQIISKIHQASTASGNTGEELEHEADTDQSWVQSSVFVARMLCRIVSSTSASVSTGRAKLIINDLREAETFIEKAKRQLNVSCRELCRSMDLAEGIWLTVMAIKQHNSDTRPSNFAKAHALSLRSIDTFSTASANYHIALSEVLHEQNLENATLHVATAAESEPSEIRYWHVIGLLSAKMEQWEAAHRALQTGTALGEVSDFAQNAEDLTNTQSTTKLSVPSQGTAKVNDHPPRAIEGLPPSDPSHSICQILSPSNKEDVPPMYAPGSNTTSSSQTQSLPPSSELLQAVADHPEPSSHEKFEYALQLRMTQVAALEYVEGAEGAAKKLLKVFQWIAEKRGMNGDQTHGKSNMVDLAGSENIRRSGAENKRATEAGMVKQSLLTLGRVINALVYKTQHIPYRESKLTGILQDSLGGRTKISIIATISPARSNLEETLSTLDYAMSAKDYIAEIERLKADVLGAREKNGILFSEETLAQMDTDRELRETENDEAKKKVEIIENQMRVVREEFEQSIGLLMKRDAELNDTKQRSDVTEADLSERKEELRAVKVPLEEETVIRRAHQQSEITLDAVANGLRSVAKGSVHDVSALFQKLALFNSLIWFFFLQPSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS98</accession>
    <name>A0ABQ8VS98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_56444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045836899" evidence="2">
        <location>
            <begin position="20"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="332" mass="33591" checksum="101956B02CEA5A3D" modified="2025-10-08" version="1">MRLPSSSSLVLATLAISSSSSTLCALAAPAGDHAQAQSGVSSSNNQFRNARRDSVSHTRSDVDYAREARSEEQTVEVQERGLVPLCSLPLIPDLLNVLGMPCPSVQAADVDTMGVMSADNTTDTTPEAAPTWSPTPSNSSTSYYPPSTSSAPSRRDVPPLPPSAPQLPADPNAILGGVTGVVTGIPGEAGDVASQAPLPQPVEDKAGTVEGALPIQPGQVPSTGTSVVKNKLGAAEGAAPQPIKNEAGTVENAVPIQPPVRRSHRARRDAPAPPSPPSHPSGPPSGAPSPPVQPPVQPPAKPPVQAPIQPPASTATVTSTSTVTETAAPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSC8</accession>
    <name>A0ABQ8VSC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_56529</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="2"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="55"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="106"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="110"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="557"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="347"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="622" mass="69070" checksum="6CF58A8F684696E3" modified="2025-10-08" version="1">MGEKVVTRPWTQKDDDLLRDAVAKYGMQDNWQAVASEVPGRDNKACRKRWLHSLSPTVKKSPWTADEDYLLLSLLSAHGPKWSFIARQIEGRTDDACSKRYSEALDPTLKKDEWTSDEEAKLLQVYSVIGGKWKEIGSQLQRSSLACRNRFKVLQRKKKPIVQTSSLTAPAQNEFESGSPYYPSGSYPLFSPEDVPATFQEPTSEVPLTSTLPPFQYSSSSLSAALEERPPISHHSPYFEAMLIDATYDHTSGSSATPSPFTFAQEFNDGSMLLDDLSDPSHYITDRNALSTFYFHHNDFGLVPDDNGICPTGPSRMEEYLPAIDTTVKSPPSGMASALHDQQVLFNESPSSFGSPELSYPSSPLGQSGASSSTSSPGVSAPAELPFEPPPLQQSLLFSSSVEVSKESARSRRHNQPTRLSALLPFSDGSLHPYACGHVQCWPADASTSASCFPTARELFEHSKIHKEPEDEKPYRCALPGCNKFWKVRKTFQSVPQDNVHIVPQSLNGLQYHLQLSSAHFQQAITKTFSSQRKSNMQPDTADGVDSDTPDHDSKRYVCDRPNCFKSYKNASGLRYHKRHGHPKTIPMQLDSVPPALARDLPSRTRKMRKKLHNPSTVATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTG3</accession>
    <name>A0ABQ8VTG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_814785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="151" mass="16925" checksum="412D51AABC9C521D" modified="2025-10-08" version="1">MFSGGLDSIKHRAGLRMKGRDGWIQAGLGDEWDDDMQDVERLRSIKLGDRQQYMTHSRPLDPPFHPPSGYLSNSSLPNRFASESEESEFHTPNVPPFDISAIPRSASPRTMAIPYSPSSVYFEPENKRKSSTNSEISTRTFSSGTKFVEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTT0</accession>
    <name>A0ABQ8VTT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047166678" evidence="1">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="16996" checksum="CE6A2645670F86A9" modified="2025-10-08" version="1">MFTLLNVFFALFAGSVFAAPIKIRSETHTINMVNNCGTGTPTLVQNGAVLNSGNSYTASGPFTAGIAYLQTGECGLNGDECTTVEMTLINPTAPGAGSSTDITLIAPHAFNKGVGFRYFNGCDGQGQTCATADCTDAFRTPTDYFAQTQCEQNNVGLTITYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUA2</accession>
    <name>A0ABQ8VUA2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WKF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_567259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019327">
        <property type="entry name" value="WKF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306:SF2">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10180">
        <property type="entry name" value="WKF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WKF" evidence="2">
        <location>
            <begin position="188"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="299" mass="34729" checksum="1152F0F84AE14ADD" modified="2025-10-08" version="1">MSLSNDEVVATHNKKQRKEKAQKAKKAKSDESDFRPAENIVRKKVADIIEMGIDRKKKKKKEKKDKDKDKEPVMDLEGAKELESFIQGAPEIEMIKQEGEFEVISEKNKEKKRKGRERRRNSELDSEGAPTARRNKRKREESGKADTEDMQEEESKKKKSRNNTGFPDPVEEALLSDQARLALTYAFNQFQKPSEWKFMKSRQNWIIRNWATDNIPDSQMPLVLRYLSNVKGNIREHLMRTCESIISTENPAHTSVVTERDSERDDDEKTHPTEKATNPMKVLRAEAMLAMFMDETKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUZ2</accession>
    <name>A0ABQ8VUZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_812212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="712"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="736"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="790"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="804"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="895" mass="98392" checksum="38E7A7308B3DA3F7" modified="2025-10-08" version="1">MPPITTADTAAEQPSSSILKERRFKLSRACDRCRRRRIKCDEGHPCQACLTASSACTFEEPGKRTHPHKSKRTATLEDRMHHLETLIQAIPPAVFAAGGNPAPNPLNPPQSDTSNAATAVPFMYPSFPSGIPPPSLHVFPLTNPSTHFTPELKPDDLQQSSPLSSFQTFMGSFYNAQNASNSEQLAEEASRLSLTASYLYFDDEGYTRWQGETSGLPLLDLLIERKAPESATVTSIPSEASPTDAPTANSDWFPNRSLRRTDVNPQTLWRMITSVIPPDLMDSLVQCYLSTSYYILPFLHVPSFLSDYGNPQKWGEPGFATFIVAICCLASRHMDDPRVRANPTDGISAGTHWFELLGRLRTLPIADQPTLYTIQADLVAAVYAVGLGRLSRAAALLSEAVTVSIDAGLHRSADTYDLFDPIEDEIRKRTFWCVYIWDKQLSAHFGRPPIIRLRDCDVAEPAAVDDEFITKDGLGVPPLGTECRMTAFISAIRIMTVLESVTDVPPIKQSSSPFLARATAMLTGMKIFNDLRDEEALLDEIHNSIPAYWAHSTETLASDDTIRVTQAQRIHSAEQFVRMLIYRHRFTKRVAERMNGDEDQKQKQSNEERDAMMSAHASALKIIAAHVHIAGKGLMTYFGVHVIHQLTQAGRTLVAILLNCKSDVMQPLISPGLDALRSCVALLRRFSGRYVCGIRSGDLLEEFCRLTEIPLEPTRQGSPQNDSRPAWIRPVRKKTLSSATRSSQSGDSPSQLDNSSPEAFSPSDFFMDPPKPATFQAGPQALPLNGVVPISTTTNSFGNNGPDQQQQQRSPSSQSFLDPSAMDLSSQLYLSHVDMMNMFGDNGVGGVDVAQMFTPEFIRAQQISTPTPGQNGIDIGQANGGSLHSGFSKLSVPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVP5</accession>
    <name>A0ABQ8VVP5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_811310</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="870"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="1391"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="119"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="166"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="564"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="789"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1620"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1620"/>
            <end position="1630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4500405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1662" mass="187902" checksum="7ADBEA6D691C4B4E" modified="2025-10-08" version="1">MSLRHSESGEIGSLRSGRGSRRQAAREPVVLAKAKARGGHELEDGFEEGTLEDTRKNSLITEKEAELTQIYEGHDSLVREAFHMEHFRMMLSYNPAEAKQDHSAVFQNYKSNYDLLETASASAPGPSRRTRRAHNERKNHLLPESSSFSPAASISALNVKTLDSPLSLSSSRNAKGKRNAIDATQDAKSSSLTRSSRDKRRNKGDVESDDSNACMDLASTINYVHTNHPYFSIPKQKRPSGILLRVPPRSSMIAPPSESISVNEFDPIRSPRKITLRGSRSTTEISPQFSLSSPTGGSRHHRAELTQAPSRFSNVLSTKRKIDLTDHGSHPEFTTPTDSVTSFQASLPPIKRIKLIVRRPAPLVSSPLQRPLPPKYNYSLSDFLSSYTTDGSQEVPPDTLAERARTRTEFLERTQKLRKEGRLLDDLSVLELTSPETANNQRKSSDIWYHCIVDAAAYLESKSKEPSGVEIAGQIAKTIQNYWDVQTVKQEKMKAQEEKRIRALAKATIKLVVAEWKKAVFHLREQERLKLVEEEVRRGRAHLDAILDQSGHILETQHGDFTRLDRSRSHSCGSSVSDWTENDSEDEAEDRKEEKDENKETCDDSFIGVDEEEGNNKEGALVVSHAQHDFSIEELDQSTLPDIVIDMDSVGGREASSTSDYHGPSDDLYHLSLPPLGTSEPVTIFAKPFNQRWDSTSNDTHEVLPPINGSTMFPPLHLDQPLDGDTSSPSTADVVTPPNEFEASIPIVELASLQGGEFMSETLPIKANSGRLGLKESFTSLAIDPLATADPNTLTSEPLNGDGESTEYSSLQIQHEEDSDDRSQEAQFPAYLTPYIVTHVDWDPDNKIAPPVLLRGVLRPYQFAGLEWLASLHSNNLNGILADEMGLGKTIQTISLLAHLACDRGIWGPHLIIVPTSVLLNWEMEFKKFLPGFRILCYHGTTKRRKELRQGWNDKYHFNVCITSYTLASRDAHIFKRKNWYYMVLDEAHMIKNFKSQRWNTLLLFRSFRRLLLTGTPLQNNLTELWALLQFLMSGAKFANLKEFGEWFSNPLEKAIEMGNVHDDETKQRVSKLHTVLRPYLLRRLKRDVEKELPNKYEHLVLCSLSKRQRFLYDEFMARAHTRDALRSGVYQKIANILMQLRKVCNHPDLFEVRPVVTAFVMDRSAVADFEIKELLIRRQFLKNESEELDLELLGLSFLNLQNTPIATTLGTRAEAAGAIMMRLCEHPGPAPPKDIRRIEKFRQYAEWQRRASLVLRWSHTAYLNRLRYSRSPIYSSETISLVRSLYNPIIPLCHVNTRTAAFVDTVLPSLHKAVLSYEERSNEMSDVIDRFAFITSNVVARDVARFALAGLLPSVLNSVPLTFHDVLHRSAVKLSIAFPSPSLLQYDCGKLQRLTTLLREKKAGGHRVLLFTQMTKILDILEIYLNFHGYLYLRLDGATSIEDRQYVTERFNKDEKIFCFIASSRSGGVGINLTGADTVIFYDSDFNPQMDRQCEDRAHRIGQIRDVHIYRFISEHTVEEAMLLKANQKRFLDDMVIQKGEFDWRSIFKFDSEDAASNIEVAQVQRGIDSGLLTKALGEFEDSEDSLAARIAEREEVDMEGADKADFGLGVVVGDDQEDALKGRSGHEGDNEDGEEDGGTTVDYMLAFISRDTEFFAEWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW42</accession>
    <name>A0ABQ8VW42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_810164</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="487" mass="51352" checksum="334F96D4B43C06B2" modified="2025-10-08" version="1">MDFPIPDSVSTSSSVQSSNINGNAAKNQRRLSSTGKVRRRLSDARDAAARPSPTALSLATLSLSPSSPSTHSFATTSAPGAISGRSGISALLTATSLESPVTLTGIPMSALPQDSAATNVGSTPASAPASMQQVINSKPINIKSGKKRGMEHKCEGCSKIYRHPSCLIKHRWEHTPHWRESSKYVLSKHQQVQLLEAAAILSHLSADSATGTSLPEDRSLWPSFLSGGTLPLPEGSNSGTSAGVSSSVPATSVLRSATASSTTLGTIPARSPSVGPRLHDYPIPTTDVTQVRPGLYMMGGSSAPASAVSPIATSLNDSYSEVRSLGPGIGYGRASSLSSSSGDSPSSQGASPSGRRVPVSNFATSSSFNSVTLSIPRSSLRSDSVFSESERSSSLEEEDEDDPMNEYHDHEFEIDVDGDGGLDISSRRRDIYAFKGRGPLEKKNFDEYGFEYEVGLGIGVPKTKVAAPFMGLDSMKEEDWEMDMDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW45</accession>
    <name>A0ABQ8VW45_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_914155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="116" mass="13379" checksum="82204B455EEE14D9" modified="2025-10-08" version="1">MSLYNCLRCTQRAGVRQFFQCRSYSVPARAQNAAPNSQTPTPKSSCPADTVLTGLNYLKNQPPVLALPDEEYPPWLWAILKPKELEDDGPGGRKERLERRRENKQRIRERNFMSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWW7</accession>
    <name>A0ABQ8VWW7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_977317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632072" evidence="1">
        <location>
            <begin position="19"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="119" mass="12784" checksum="6E0C31F34E30D700" modified="2025-10-08" version="1">MHFNLAFFIIGLVSLVSGLPIAHPVSSTTVQVHSPRMNKPVPPPLTVVSVTIKYNSALPQQWITDALKTDSGSTTPTFTADAKQKGAEAEIALKDPNGGKHTKNVKLKLKVTAMYYAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWY5</accession>
    <name>A0ABQ8VWY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="55" mass="6534" checksum="5569ED4BAE9A172F" modified="2025-10-08" version="1">MDLVDYYGAMYHYPSLYLITFARVNLPAILAKTWRKRTVYTTFTLYKVPILLRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXA4</accession>
    <name>A0ABQ8VXA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_892630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="39356" checksum="5DDDC2671599C6DC" modified="2025-10-08" version="1">MQHLIEGSSQTVLPPSPYPTLPIEILDSVLRCVQSRDDIRNVTISNKHLSAVAVRVLYHTIRLEKPMESVKCLRILSQNTRLALLVRSLDIHWPFISYPTRNMYTLAIRALCNTTLLNTLSIDGPTDFHPWDLSECSFQLKKFSASFPYDDSLIRFLEAQPSLLDLTLRGFNSDPAKFSLNLSTFNLNPNPTPFSLSPGALPRLSRLRAIHAGPDIIASILEGRPVTQVSMPLYADCVYRSLHVLNMSSEPIERLNIISFDPNAPVYLLDEIASRLPNLEALHIVILLAQCSEYLTYMSATSSDDVSQDDEQKIAAMWHKSCPTLKTIILPMGKVWFIDNSKWMCLEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXQ4</accession>
    <name>A0ABQ8VXQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transcription factor iiia</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_811166</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="155"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="188"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="313"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="344"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="504" mass="57050" checksum="422C4C18F38BBC35" modified="2025-10-08" version="1">MLATVSVLGKRKASVSESKGYVLHLNSSPEPQTALSESEYEPEASSSKKPVIINGKLISGTTKWYQCTVEGCGKAYLKPSRLEEHSRSHTGIRPFVCSTCQKSYLRETHLQAHARVHLPASERPFVCSLPNCEKRFWTQQHLRAHVDWHKGLKTFPCTEPDCNDIFGKHHQLRSHICSVHSPPGTKPYSCTHAGCTKSFDTNQHLRTHLRVHNDKRYTCVNEACLPTAEHPIVFYPTWTALQHHTRMAHPPTCTNPSCNGRVFASQKGLRLHQRIHEQRDEETQLNAVVFESDRDDEQPPKKRRRGGEHGRDWKCEVEGCEKDFKSSKALNVHHKVTHLGRKDFICSHESCGASFGYKHLLQRHVVRLHFKHSDNSSTDKRDAYQDASSSSGSDVPTKPLMGIEDITGSAYSSRAQELLGTTQAIRCPYPHLQDISFVLCSRDDETATEQLGGTESTLAGPYCAYVFRRAYDLRRHLRAIHKVEAEKESTDLWVSKMKLKEIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYE2</accession>
    <name>A0ABQ8VYE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="337" mass="37651" checksum="86F6D1ABD5DD679C" modified="2025-10-08" version="1">MGSNFKFPQVSCFEISLALIEMDLGENRCVCLGEVGVKDAVKPGVYQEVPFVRGGYRRPPIPICIICEDTQSAAFIYGLLQPYVKANASERNFVQEFLESAAFQAVANEVDKRPGFRWAVKHGKSVGVFLSGIEALLSVDLAEDVKWKQAYAFHTLKEAVLFQMQGNRNPANYVWEYNPLQQPDTADTIRQLVEQPLTPVPSPPPTPPPAPKSPKKATSKSHSSSDASILSRSPPQTPSRSQGAGSSTGIRFFASPQIYVNVNQEPTTMDRRSHLADGAYWSRRIMANLHFTPSAADKVENAVNTYSKADFVQWFHIKFPHVEETWAEFMWDMHARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYT5</accession>
    <name>A0ABQ8VYT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proteasome complex subunit Rpn13 ubiquitin receptor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_749437</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13314">
        <property type="entry name" value="PH_Rpn13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.70">
        <property type="entry name" value="Proteasomal ubiquitin receptor Rpn13/ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044867">
        <property type="entry name" value="DEUBAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006773">
        <property type="entry name" value="Rpn13/ADRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044868">
        <property type="entry name" value="Rpn13/ADRM1_Pru"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038633">
        <property type="entry name" value="Rpn13/ADRM1_Pru_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032368">
        <property type="entry name" value="RPN13_DEUBAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038108">
        <property type="entry name" value="RPN13_DEUBAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225">
        <property type="entry name" value="ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225:SF0">
        <property type="entry name" value="PROTEASOMAL UBIQUITIN RECEPTOR ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04683">
        <property type="entry name" value="Rpn13_ADRM1_Pru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16550">
        <property type="entry name" value="RPN13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51916">
        <property type="entry name" value="DEUBAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51917">
        <property type="entry name" value="PRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pru" evidence="8">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="DEUBAD" evidence="7">
        <location>
            <begin position="166"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="30318" checksum="E69E1CF1282444B9" modified="2025-10-08" version="1">MGDSGTLLAFKAGRAFRREGTNFVDPSPAKGAILLRKEDDLLHLMWKNRTSNEVEEDLILFPSDATFLKVSQAPGRVYVLKFSSSNQRHFFWMQDASSARDEEFVNNVNGFLMDPDYEASWGSSSQPSTSTSTAGASQSSAPSNFQATPEQLAQLQQLLTSAVGSGAPPHSDVSLNDILTPANITPLFTSHPDLIPTLFPHLPPDLPMPPSPEVLQRIISSPQFRSAVSSFDQALRTGLLGGLVRGLGLPEEAGTGIEPFLRAIQSQAESERGEDSMDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYW0</accession>
    <name>A0ABQ8VYW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_976542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21503" checksum="02CB545410846FFB" modified="2025-10-08" version="1">MGNVASKAPKTARKLPKRTEPPTWTGYNSTNPQQQSSGAVHKRPLAGEKKDEAIEVDSRDPHFMSNLSRLGVVEVDHHMKAVRPHQRSRDMIESRKQSEQEAASMHPSRNHVQASTLSYLLDKSKSNASRRELTELADKYGVDIEKIESLSRYITSPSINSNSVVRKVRNQDGEEELSVMAIWVESRALKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZM3</accession>
    <name>A0ABQ8VZM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_805923</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="574" mass="62752" checksum="A188F9D9226D396B" modified="2025-10-08" version="1">MQLPLDIASITNTWSQLMALMLDVNVTSSLATINWDNLNSSVNGKLFQYAPFARACFKDAERVVGAYDANACAFAQAHYSDGQYRDTIPSSYQGLQWETCPSTGESCLLDWMNPLNEAAFDYPKACQQGSIPAYFLEVQSASDVQDAFKFSVETGVDLVVKNTGHEFQGRSARPGSLALWTKNLQKIAYEPAWIPTGCEDIAPRTAVRLEPGITFNDLYAFGEANNITLPGGSTPSVSATGGYVLGGGHGGLSNTAGLGADRALEFTVVVPTGDVLIANACQNQDLFFALRGGGGGTFGVVMETVTLALPRTPIQVVTLDGLSTDVNTTRAFWKVLVDNSLVWANAGWGGYAAATSLQYINPLPITEEEAQTSMQPLTDFAAQLGLTVIHEQYESFAVFYQQILEPLYAISGFPLSTSSRLLPAQNFETPELREELLDALLNASANHSLTYVFATTPYAYKADNLTSVTPAWRDSLLLIEVLDTLEYNTTASEQREVIEGLSKSMDFLRNITPTSGTYFSESDLYEPDHEKSFWGANYEKLAEIKLKYDPQHVLDCWHCVGWKGQSDQAYSCYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZQ5</accession>
    <name>A0ABQ8VZQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045599243" evidence="1">
        <location>
            <begin position="20"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="200" mass="21997" checksum="230314EEDE239025" modified="2025-10-08" version="1">MRFLTSLLPLITLALRVAATDPSPGSNSIPLTDIGRPAPAHLYGNNVYFADEEAANPGADPQQPPCRNCLEKAKNIVAAKIKAPVRHLDVVMGTSLQKIIDHPIPSLFIFLGCVAVGTGVLAIYCHFEEHEHPWCHDYLKLGHIHRRDSGYPSCQQLECGDDVCGVPQTSLTSGGHPKRDLARTLYRRRLEGLDDEDKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1X3</accession>
    <name>A0ABQ8W1X3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="24059" checksum="3BE47D2EB113CD8A" modified="2025-10-08" version="1">MSTKVPAPRFSVVITPPPSTSSSPVPCMNMCPTPPLCVATSGPITVFVPGAYCLLTTTGNCVFVTVGYCPIGIGAYCAFVIGGYEFGIAGYCALATDGYMKKEHLPSLPLPVKKQESASVSFPDVLPPVSVPQPSAGPSARIRSATPNQHHPVPRTSDHTPTTSQRKSRRLKRSPLPPSSRQLRPRVNKITYNENGISLHIYVLPQLRFFSHPALIRSYMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2T2</accession>
    <name>A0ABQ8W2T2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">beta-glucosidase</fullName>
            <ecNumber evidence="3 6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_805469</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 6"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="7">
        <location>
            <begin position="411"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="852" mass="94113" checksum="6D042535C71C9EDC" modified="2025-10-08" version="1">MYPSMSRSFTVADVDDLVTKLQTEEKISLLSAPNWWNTTPIPRLDIPSIRCSDGPNGVRGSSHFASIPAQCLPCATSLASTFDVDLIRRVGEFLAAEAKIKSSVILLAPTCNIQRSPLGGRAFESFSEDPYLSGIMASAYINGLQSQGVSAAIKHFVGNDQEHERTAVESVMSDRALREVYLYPFMLAQKLAKPWAFMTSYGRIHGVHCSENPELLQDILRNEWKFNGIVMSDWYGTYGVDQPINAGLDLEMPGPTRWRTPTLVNHVLTAQKLSPSTLDDRVRNMLSYIQQQARLNPEVVYGDGKERTRDTPEIRQFCRAVAAEGIVLLQNRNKVLPLLPNRIRKLAIVGPNAKGSVISGGGSAALKASYIITPYQGIQQGAFDDLQISYTIGCYAHKYLPTLENHLETPNGEPGWLATFYSHTEDGELTPPVAEFVLNDTRVKLNDFIPAGLSENWTLKMTGRLSVDITAPFELGLTVAGRAKLWIDGELTIDNWTKQTPGDFFYGQGTIEEKATVKLEAGKKVDVLVEYTNSYPPPNQNDEGKTVPNAQPALMRGLRLGGCEKIDAELAIADAVKLAESSDAVVFIGGLTAEWESEGFDRLSLDLPGMQTELIAKLAAVNPNTIVCIQAGSATAMPWKDEVAGILQTWYLGNEVGNAIADVLFGKVNPSGRLPLTFPKRIEDIAAYPNLRSEHGKIYYREDLMVGYKHHLKQKIEPLFGFGHGLSYTSFELLDCIVKQTGTDIETSVRLQNTGAIAGSEVLQLYVAYPDKGITHPPLQLKAFAKVHDVAAGQVSTVKLKLDKWAFSYWDEKKNQWKVDAGHYALYLGFSCEHILHEKIIELGNMLSWTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZVD3</accession>
    <name>A0A9W8ZVD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8J55DRAFT_228054</name>
        <name evidence="4" type="ORF">C8R41DRAFT_886510</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000041">
        <property type="protein sequence ID" value="KAJ4467387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZVD3"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000023">
        <property type="entry name" value="NEDD8 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4479419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="77" mass="8566" checksum="541DAEC7EF821645" modified="2023-11-08" version="1">MLIKVRTLTGKELEIDVDSDAKIFTIKEKVEEQQGIPPVQQRLIFGGKQLDDDKHITETNIVAGSTLHLVLALRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AF67</accession>
    <name>A0A9W9AF67_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3 11">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8J55DRAFT_428534</name>
        <name evidence="14" type="ORF">C8R41DRAFT_872679</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3 11"/>
    <dbReference type="EMBL" id="JANVFS010000015">
        <property type="protein sequence ID" value="KAJ4480517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AF67"/>
    <dbReference type="SMR" id="A0A9W9AF67"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
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    </dbReference>
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        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
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    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="12">
        <location>
            <begin position="4"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4480517.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ4501625.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="151" mass="16526" checksum="C9DB2DA899F65D96" modified="2023-11-08" version="1">MSTKEQTYIMVKPDGVQRGLVGDIIARFEKRGFKLVALKLVQATTEHLEKHYADLKGKPFFPGLIKYMASGPVVAMVWEGLDAVKTGRVMLGATNPLASAPGTIRGDYALAVGRNICHGSDAVESAQKEIALWFPEGLVQYTNTLEGWVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DHE3</accession>
    <name>A0A9W9DHE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_437204</name>
        <name evidence="3" type="ORF">C8R41DRAFT_773778</name>
        <name evidence="1" type="ORF">C8R41DRAFT_784491</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000181">
        <property type="protein sequence ID" value="KAJ4463304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000035">
        <property type="protein sequence ID" value="KAJ4469514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="KAJ4476249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DHE3"/>
    <dbReference type="OrthoDB" id="3260546at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="111" mass="13341" checksum="5E0EE8D9BEF3BBF7" modified="2023-11-08" version="1" fragment="single">MKVRRYFDDLENLFTDCNINNELDKKKWTVRYPEEQVAWEWKAMSEYSTATSTFTDFKKVVLSSYPGATDEERGTMRELNRLFKKYKNIGSDDLDEYMALVRRFRAVKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWT2</accession>
    <name>A0ABQ8UWT2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_985500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="553"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="677" mass="72528" checksum="2DDF38101C550705" modified="2025-10-08" version="1">MAKRSANHPRIDQDDLSSSLKVERPTSILYPAVSSDSDQQSASQSGSKDSSSGSQTKIEDEDNESGVSRPIMSLPSSAMQVDGLPSSSAIVDPTMRVKNESVVTKAELDLIPCPISSSQASASTSSSDFSHHSRPNLDDRQTHGGTDDSEDGSGSDTDTESNVGDSKSGNGLEHTDTEIIGDVSASSAGYSGSQSSLMSVPSQLIRDTMDEVLAKSNDGHNDEEGEEGTGKLRGSLELSGHEEYEARCTNIDEDRDTDSDTETERGIGRSCAYTSFSTVSSISPTSSTSDLSSSSQSSISFELDDPPPPPPAISSVAGPTTTTHFKQPPAPPSPQTGHPDIPVLWSERDAAAELPKNHNPRGMNENFQASRTNYILGFSDVLPHDSKYKYGVGDVHPRKIHDVVEETKGCASLISSVNSHVPRIDHSDPLNVADSSSRTHMMLDSESISSKDLVSSPLVDVPNTTIKSNDQLEKIRATKISDNENETSPLDLSTSAGQSSALFSDDRTSTPTPAILMTSPLKRKRSRGVEHLSECISATQCIENNWDRDILFAPSLPSPSSNTTPSASGVTMPQRPPRKRARTENNPPLSTSQRPDSTKRPLTASASTNSVFSPPARRDLLRRARSHASVFTRPSSEPSANIEDLQGDTKLSLSVLWKFGFTSNGKENVKGKERSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ42</accession>
    <name>A0ABQ8UZ42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione hydrolase</fullName>
            <ecNumber evidence="1">2.3.2.2</ecNumber>
            <ecNumber evidence="1">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_871705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="1"/>
    <dbReference type="EC" id="3.4.19.13" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000118">
        <property type="protein sequence ID" value="KAJ4466079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047441210" description="Glutathione hydrolase" evidence="2">
        <location>
            <begin position="27"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="589" mass="63660" checksum="7B5F0AF9DCE4DEAC" modified="2025-10-08" version="1">MFAGQLRLIVSFLLLAAGTILPVSRAAAIHTSDQVFLQEAAPHGGVATEAAPCTKIGLDVLQQGGNAADAASSQIIASGLCVGVISAYHSGIGGGGFMLVRFNKDDGSHDYEMIDFRETSPSDAHEYMFVDSSDAEASVVGGLSVGVPGDLRGWEMLHQRHGSMPWEYLVMPAVHLARNGFEVDVDLAAAMQGQNFITQDVIWAETYAPNGSVLVQGDICYRKRFAETLEKIAKYGVDAFYTGDIALNTISTLRQNNGIMTLDDLASYTAVVRQPQNITYRNTRIYSTVAPSSGAVVLSALKIFEGLSGNISHSDPSIHLNTHRLIEATRFAYGQRTEYGDPAFTSNVSQLEAYFLTEAVVTQTRNKIVDNKTFPVTYYNPENYQVVIDNGTSHIAVIDKNGMAVSLTTTINNYWGSQLMTADGVILNDEMGDFSSPGLLDDFGFSASPANYIAGRKRPQSSISSTIAEDLETGDIIIATGSAGGSRIITATLQHLHHHIDQGLNSSSCVHHPRWHDQLDGNTYFEYDSETVGIAGYDDATMAYFRKIGYNISYMSTERSTAHVVIRQPNGTIEAANDPRKAAGAGLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0L6</accession>
    <name>A0ABQ8V0L6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_898144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="18"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="58"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="49070" checksum="104D60E0BAE1EFFE" modified="2025-10-08" version="1">MPSDYQSNIDLAENVSLDPLAVGRSRCMANIAFSAGSIILSNSSFIDILLPSEKGHRCDHCHNLSGIGSLKRCTGCASFYYCDHTCQSKHWKSGHRKICKLYNTYISAASFQALEEHKKMDALLLSSLIAHLSSVDAKERDENTAFLTFQSLLPGPMTTSAPPICPKHSFTAGVIDGFYSRFENNNFSIHSHFNTYAHGIFPIASRLFNHSCMPNAAVKFIIQVHKPVKLEIVALRAISKGDEICIPYIDPALLQTRTTIFDLTYGFTCSCPSCNVIRKVGFIPEPPKEPVRFQAVCERLREFVGVMGLSPFLTGDDSLFPTELTCVLHESFISTLSEQFSAASHDGRYDVALESSSSLFALYQLIYPLNYPQIGKCLHLLEKAKTCWNHIVRSTSTMEVAAELKNSVVAAKQILTVIGHEGDHDDGPLAEIETLLLEVETYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Y2</accession>
    <name>A0ABQ8V0Y2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_38154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF106">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="42779" checksum="98EA53F7B66F80E9" modified="2025-10-08" version="1">MVTHLAPSNSRLYDPPFDWDPSMDFPSDTEDSDACSLSSSSIFSSPPSPSTPRTSYVPSARSASPAPSVLSMTSSMRAQAFKHEYGRGLNNYSEVYRLPADDEELERLDAQHLLFMEIMGKYPPCMEEVMADDVPGEIKAVLDLGCGSGSWIMDVARDFAHCSAVAVDLVPMQSIYMPPNLRSEVDDINLGLEHFYGDFNVVHARLISSGVRDYEGLINQISMILRPGGLIDLMEFDFHVYDENHQVIELETSKIAEPWWPRWLTFANLAARDRGGNVDAATYIHSWVANHHAFENVTYEEYWVPTCGWRTDSEFMMRIGVTLRDDILAFLKSGRPLLLGSGVPEDLVNELEANAVKELHSGRARHYIRLQCVHARKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V142</accession>
    <name>A0ABQ8V142_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-5-taurinomethyluridine 2-sulfurtransferase</fullName>
            <ecNumber evidence="3">2.8.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_778398</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP = 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47040"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11732"/>
            <dbReference type="Rhea" id="RHEA-COMP:11733"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:87171"/>
            <dbReference type="ChEBI" id="CHEBI:87172"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="MnmA_TRMU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="MnmA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046885">
        <property type="entry name" value="MnmA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046884">
        <property type="entry name" value="MnmA-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="MnmA-like_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001138">
        <property type="entry name" value="PRK00143.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933:SF5">
        <property type="entry name" value="MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933">
        <property type="entry name" value="TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20258">
        <property type="entry name" value="tRNA_Me_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20259">
        <property type="entry name" value="tRNA_Me_trans_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA-specific 2-thiouridylase MnmA-like central" evidence="14">
        <location>
            <begin position="211"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-specific 2-thiouridylase MnmA-like C-terminal" evidence="13">
        <location>
            <begin position="283"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="391"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4468957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="447" mass="50694" checksum="C84C77B56239FDA4" modified="2025-10-08" version="1">MSGGVDSSVTARLLANQDYDLSAIFMRNWDTRDESGTDKGCEWEKDWDDVQRVCKSLGIPCTMIDLSREYWNRIFQPALDVWESGSTPNPDVWCNREIKFGALLERLPVDPITGTSWFATGHYARKRWSPNGRPQLLSAKDQTKDQSYYLSSISEQGLARALFPLGEITKVEVRELARKYQLATAEKPESMGLCFVGERGKFSQFLSNRLVDSYLRPNPGPIIDSTMQKVIGQHEGLWTYTIGENAKVAGQPFKMFVSHKDPTKNAIYVVPSSNHQALLEHRVICKEWKWIWNDAPPATVFEPAGFRAAVKVRHRQDVQSCIAKTAHDGKLEIITDEPMRGVSLGQVAALWDGDWCLGCGVIAATSNSLLQPRHIVDGRVNPSQFAKKVNQFQKKRNTKSRGEGPPERSQLQKPSPGSWLFQDRKYQYEAPPLDKLDKLSKEKKYWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V198</accession>
    <name>A0ABQ8V198_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_782799</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="812"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="851"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="957"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1056"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1087"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="179"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="521"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="816"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1149"/>
            <end position="1390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4464406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1409" mass="157170" checksum="92B33267E218A26C" modified="2025-10-08" version="1">MYTTTLSLLSMLISFPRWRVIFRRHLNIVLCVTCVVNGYIDLFPLATTIKMPPDTCKGWLLWLELALLGVAGILIPVLTPREYVPVDPKHPMPKPNPEQTASIFSLGMFFFLDPVVFEAYGVPHLPYERLPPLADTDSIKHLKGMHFRHLDPFSGAKPQNILVNLIRSFRYEIVILWTLAASSAVVLFGEPAAVNQLLRELLEEASSSMMRVWFWILILFLVTFVDSLLTEWYLRLSLQTVVHLEALLTQLVFEHALRIRVKAEPSSSSIDLDSEVEKGHKKNDFNLVGKINNLVTTDLTVISDARNCIALISEIPVLLSLYAVFLHNILGWSAFVGICLTIMLAPIPACISRITRKYQALRMKKTDARVNVLTDIMNILRMVKLFGWEKRMLWKISEAREEELSLLSKRQYTNLWGSVSNFSIPIVAMAGTYAAYTLIMKQDLTASAVFSSLVVFENLQRYINAIFMYWTRALAAKVSLDRFTNFLLDTELLDNHNPSSSSTQALDVGNSDVVESSPDEIGFCNASFSWSSNTNRTDTPSGRKFILKINDKLSFKRGGLNLITGPTGSGKTSMLHALLGEMHFIRSGPDSQDDGGSSLSLIVAYAAQESWVQNETIKNNILFASEYNETRYKEVIYACGLERDLELFDAGDDTEVGEKGITLSGGQKARLTLARAVYSSASTLLLDDVLAALDVHTSKWIVEKCFAGELLKDRTIIIVTHNVRLVEPLASSIITMKDGQVYESRFYSPTAIEDLSETLHSNVDGEDLVNPSPKGQSKSNGKLVVPEEIQEGHISGNSIKLYTSAAGGKHPVLYFATLLAMMVLTQFMGVVQTWFLGFWSSQYEMPGKVHVVFYLGIYVIMLFFVIMLNAGTTGIYISGAIRASRRIHKQLAEMILGTTIRRVHSQTLVINDANVSSRWLDKTPTSRIVTRFTQDINAVDTFIPEWARLFLDQTLKLILKLAAIVILSPIFFIPGVLAVVLGYTCARIYLKSQMSVRREMLVAKAPVLGHFGATISGLTSIRAYGAQNMITERLSSRIDRYSRSARIFYNLQRWMALRMHIISALFIALLAWYLVYVQKDNASNTGFSINMGATFTGAIFGWIINMNMLEVVEAFYSLERVNSYLQIEQEPKPTAQGAPPAYWPATGELRVDKLCARYSPDGPEVLHQLSFSIKSGERIGVVGRTGSGKSSLAFSLLRGIYTTGEVMYDGISTSSMNLDSLRSNITIIPQVPELISGTLRQNLDPFEEIDDLTLNDTLRSAGLDALQEDMAVNEDKLSLDTVISGGGSNLSVGQRQIVALARALVRRSKLLILDEGELTGNTDYKTDNIIQNSLRKELNKDVTLITIAHRLHTIMDYDKIMVLEAGNIVEYGVPSELLTQEDGKFRALIEGSNEKEALYALSQVNAHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1V0</accession>
    <name>A0ABQ8V1V0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_898475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="80"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="277"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4465719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="473" mass="52031" checksum="1D71E01E15DC0B7B" modified="2025-10-08" version="1">MDAANYANPLTELATILYSGIETLLSEYNHQGVAFPLLSQPFTPSPLDTNSVVNESTCLIIAAAHQIIATVRAPAESIQEHATGAYTATALNLCVDVHVADILQGAGAQGIHTRELGTKTNIATKHLYSTARILRYLSTRHIFQEIEPDVFANNRISSLLIKPHSLNEIDANPDIEFEGATLAGFVGHATDECLKASVLIVPWLKDKSTQFPSPFNMSIGSSISLFEWFEAPENTRRLRRATAAMTGGGERFPATIFTNVTHCLTILGFNWKSLKEDAVVVDVGGSVGSVTYTIFQQNKHLRYVIQDLESIINKEAKQYWEEKMPQALTDGQVTLQVTNFFEFQPVQNAAVYFLRLILHDWPDEKCLAILKILRRAAGPLSKLIVFEQIMAYSCKYSGPFADVSNPIKAPAPLLANLGMGAGGFITMIDMQMLTLFNGKERTVTEFINLGSLTGWELEDVKPGLMNAMVFSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V215</accession>
    <name>A0ABQ8V215_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular metalloproteinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046423706" description="Extracellular metalloproteinase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13551" checksum="D6FDE8A009F1D39D" modified="2025-10-08" version="1">MRFSLVYLALGLASAAYAAPSTARSPRLVTVTFHDRSAGAKLSATTSELELDPKVKSGLDRVMQKYGPGGPHEFQYTHNFENVDDKGFSVAMTGFKPCKNGYTCVFNVLYDEATKPVLISLIPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V250</accession>
    <name>A0ABQ8V250_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_778921</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="5">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4468082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="171" mass="18758" checksum="17FC93E9A65C93B6" modified="2025-10-08" version="1" fragment="single">LPALARLPRSWNLLYSLDQHGISLHTLYNKCENQPQLKVSSAFTSKVSALVVMKDSGDAIFGVYMGDGVRQSKGKGYYGSGESFLWRYVNGNLQVYKWTGKNEYVALCEPEFLSFGGGDGVYGLYLDESLFDGSSARCPTFDNEPLCSPGDRKGRAVSFECVGLEVWGVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V269</accession>
    <name>A0ABQ8V269_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Salicylate hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_870746</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4470477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11367" checksum="68DC5EC6A515506B" modified="2025-10-08" version="1">MTEPTKFRIAILGGGIGGLACAVALKDHTNIEIDVYEQAAQITEIGAGVTVWPRTWEILKLLGLEEDLSVLLKEAPSNVQSWYYLLHLYPRLTVYGLDQTCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2X5</accession>
    <name>A0ABQ8V2X5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_851516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4471009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="40803" checksum="355F57A08A9C1747" modified="2025-10-08" version="1">MSSAEYHGLQIMTACIQFIGVSFLSFCLSRRVPTGWRQWRYLTWGRTCVLLVLLDSWIFVFFSGLLSSGVGLSWSHTTCTIAIYSCISFYAISKILIYAFLSEKVYIVWTGGNQVSRYKTKVYRLCAFVLLGYIVIGILMILGRDSSVRGDGVCVIGLKAFATIPLIAYDLSLNIFLTAMFMCPLWVLHPISPKLRSVAKRTLYGATISLISSAVNITIMLLLSGNELGWVCITSCVCDVLVNSFAVFCVSSSSDSSDVVRDRFSLPTMDMTPLTFTQTELSQPTGESSIKRFISNTLEPDGLSVIPEAYYDYLPPQHRQADPEKSVISISPFKPDTVSQSLSLIPTTSIHLPPPALHGQSLKISTNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V329</accession>
    <name>A0ABQ8V329_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA intron endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_897766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018593">
        <property type="entry name" value="tRNA-endonuc_su_Sen15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28582">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28582:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09631">
        <property type="entry name" value="Sen15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen15" evidence="3">
        <location>
            <begin position="27"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4471665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="123" mass="13509" checksum="A3CAED654F221CF6" modified="2025-10-08" version="1">MLEIHPSYPALASVAEKYPTHQGSLFQTYNDILLAQQWRDVQVIDLVLCKRGALQGRRPRTAADADLLLHIVPCSLAESISLAWIQDVFAALANPPSIYLAVVSDDSSIVYYKLSSGIVKPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V348</accession>
    <name>A0ABQ8V348_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_852170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="123" mass="13202" checksum="104378F08B98AAA1" modified="2025-10-08" version="1">MSTRANRVSSADNPSASGTPTAKAQRGRRQTRSSTDASTVVPVSSTNKKRKKPVQTVEPLGTQTKKARGSPRAASGMVSRGGGATTPRNRPSEGTRQTRYRAVTINVDEEEGICLFIFHYPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3F9</accession>
    <name>A0ABQ8V3F9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD-P-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4472410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32485" checksum="A079CF40EFD06886" modified="2025-10-08" version="1">MSRPQFENLPVTVRHDVYPAISPESYFSGSSFRDKIVLVVGASRGIGLSISTFYARAGAKLAIVSRSQKALDMAKSQIHLEVESSAKPEVFSDVADVTDTNAIAEVVRKVVDNYGRLDIVVANAGTSSPWDKPFVKTDPDVDWWKTVEVNLRGVYNVAHYSLPHLEKTNGAFVAVSSMAAQINLPFASAYVVSKAALNRFVEYVSIEHPGVKSFSVHPGSIQTEMALAVLSNWESVPVDTLQLPAATILKLTDGSGRFDWLSGKFVSANWDLEEVERDWKEKIVNEGLLVTRIVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3R2</accession>
    <name>A0ABQ8V3R2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_849537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4472713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="167" mass="18246" checksum="3C4980F688945567" modified="2025-10-08" version="1">MYHMAIQKFKSRGWTNSAPPVGINDAGLRKPYMDLAEMIPPRSVLDLLPKPPMTPFKIFFYIDEAHTLTALNGLPSPFIHLRSALSRLYSLAFAVFLSTHSQVAELAGREEIYSASARGSPSKSIPPFTEMPFDLMSGSNGKLKLSALCPTEVDSVSFLSLSLGGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V413</accession>
    <name>A0ABQ8V413_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_926644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000129">
        <property type="protein sequence ID" value="KAJ4465214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00179">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="230"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4465214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="37131" checksum="31A2693FA43AE555" modified="2025-10-08" version="1">MANDRLAALRAQQSGASQMSSNSYPTQASGGGGGGYQSRRANPYAQQDGAYEMADVKESTTNLSGGTDDMSSFYAEISSLQDSIRTFNENVTRIGELHSRSLNNTDDVAAQRNAAQLDELVADTSALSATLKRRVKALERTAGSGRDGQIRKQQTALVKSKFVEAIQNYQNVEQQYRTRYKQRMERQFKIVKPDASPEEVKAVVNDESGGQIFSQALLNSNRYGESRAAYREVQERHEDIKRIEKTLGELAQLFNDMSVLVEQQDETIQNIETTAATVEKDTEAGLNYTEKAVVSARAARKKRWICFIIILIILAIIGIVVGIEVARNVNSNKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4H3</accession>
    <name>A0ABQ8V4H3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_968557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="30174" checksum="49CC0824C0CBEA4A" modified="2025-10-08" version="1">MDDPLWPLLAAACLPCSSCVRSKKSGSCSVVPHLARCSNCDDKKPCVLGRLARFRYFARKCSRDLSYAHRFLEVHGDPRQRTRFSLLPEQWRTIANKIESSTNSTQVLLELSLLDDQDRLEEDRLELQDFVRRQPRFPIVEEAIPSGPRRSPAPGKVPSIPKKRKRTIRVGEPSSSKRKHSVEPDSGLGNAPDYRRVVLVLPPRLRVVRRLWSHTLRVVWTLRNRPPLHYLLLGSLPLLHLVLTPPMEVEQLSLVHLASSFPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Y4</accession>
    <name>A0ABQ8V4Y4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_849914</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="123"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="371"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="531"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="607"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="678"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="435"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="683"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4472693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="784" mass="85421" checksum="D3EB6721E6463B92" modified="2025-10-08" version="1">MFRSKLVPLAQLERRLYSMAGSDYDRDRDISPSSGSSVEPSSVHHCQWQDCSQSFVDPETLYNHLCNEHIGRKSTNNLCLTCKWKDCGTSCAKRDHITSHLRVHTPLKPHVCEICKKSFKRPQDLKKHEKIHTEEHHAAHKHSKAITVVDPVYVSRVRKESGNHSENKSEKDKPVSRIRAPTPRSVSHSSASPESSLPTPSPELTPPHHHTHHSPLHDDLFIHNQLPPWDGLRSDSNAVHVSAGSKRSHDNDYSVDDFFNDMKKRRVNPSYDPGMVERLNNMAYNHSHSNVPFNPRSVSLDIRTPEELAAVNEFLVTLGRDVSGMIPSTRLGHHTRSQGSFPSESFFDSVALSQLGLTGMPGLPPTENFVSAPSSYAGGPPTSATFTHRPGSSGMYSGVGGEAAPGRHSSRYSHLQQYDFPGSGTYHQLTPPLDPSSESPHSTSTPVSMHAMAQSLSNNSRYSALSPIYSSHPSVSGQFGVHLNPSAESVAGFDYLRAPRGPVPDVGLTIPESIGADKAVRRPMVLLKSIPSKEDPSTIASSVGAPPEPLEPKLTHGIHRGPPAKLPSIESSSSRKLTPVPSSSTSASALYPTLTLTEGDAQYKLPPLKSFCPDSPSLASRPSTPSSVDDSPRPQTTVLPSLKSLTAVGSVSLHPPRPKRSLTGESDELAREVGKIELTGPGAHSPALLHSSSSSSAYAERGSPLPRKPFHDVNIPLDERRRHAEFIRTLLVAINEDYMKRSGSESNRSSVKQENDDRMDVDEAAVVKPRPSCNSSVDIEMCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5S7</accession>
    <name>A0ABQ8V5S7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CDP-alcohol phosphatidyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_889662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000097">
        <property type="protein sequence ID" value="KAJ4469163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4469163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="258" mass="28665" checksum="8987CEBE76F17170" modified="2025-10-08" version="1">MFLIYNASNRFLRIPSSIPRVTINYGKRRTTLAHASILISRSNFSTEEPKRKPALRENIYTIPNLLTASRILACPAIGWSILQGQFDLATSLLVYAGLTDLADGWIARRFKMNSVLGTILDPAADKALMTTLTVTLSMKGMLPIPLAVLILGRDVLLSLSAFYIRYTSLPPPKTFSRYWDFGIPSAEVRPTEISKINTGLQLLLMGTTTISPLLPWALDVPLTGLQWIVATTTIWSGISYVFAKDGYRVVAEKQKEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V650</accession>
    <name>A0ABQ8V650_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="905"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="955"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1279"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="972"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1332" mass="145456" checksum="328104F0218591A1" modified="2025-10-08" version="1">MANKSLNSPSFSRFSRMGFGLRIKSQSASPSPRIRDSAKSNQDNDWYIPYNGPYEPPRDTYVRGKEPLRDSWGDPVVDAQAENDEENPIFSDAELHTRYRNWNPAEERKGRPRARTQSSSSGTVDPSRASMATGRRSTVSHVGNPPAVPSYISLSGGVGESPVPIPRAVRETASTKRKSLASLFTFNSTSRKLSSSSKAERQHIPNNNTPSRLSDQGLHSIGLSKLPETAYLPSDPVAAVVLFGASAATGDEEYYNSYYSSLINQPQNNHQTARQPPDTSFQHTPQQPSSPQSPLNSEPSSATHPYAYAYSTSTPSAAETPRSAPPPKTHFERTPIHHLYPEKSRVVSPAQILKSKSIPQTKPHLPGHTLSLKNSTSSPDLRSNNRSKSLIPRGKDRWLSPETWCDALLFPRPRFRLKQDKDASASNHAGSGRIVSPPGSPVLGYFSNANAAQPSITSRVLAHSRSMVDLNKPIVAEPSTLPRIEAHSPPDPLRIAGPSEQSSPFRAPRPKSWALDDLALPSPVPSLARVLEEGQILEHQRKKWQAQAVNSFQNHRARSLSRTRTKSLSSKQPKRKDNSKLDFLAARGLLGDQNIIPVNVVKPRQRSDSQTESRGTTVGQTSSHHHHTSSLSKTLTKSSNKTHSRNHSRTESIGRSAVRMVRNTANHLCAFDGEGVSPAEEKMAGIEGALQNNATKVITFADPAQIYVESPLPSRNGHSVSPTPSGISDSRMGIALTTPPMTEENFEPIRMPAHPYAQGGFSFLTPHIDFQSNARVDLPSAQVKPSQESRIQNPIPVPTSWHPYAQAGSFARDSYQSEMKITPRLRSDSDVPPPQKMWAQWSSGVVQEILPTELQYSPYLPDQKSMVEDDSQVRKQVRNSSPIYNTAGVGEALAFATMQRYSRDSGVGTSEEHASAQAEYEAGSISSNRYRKTTQYDVTRPLYLQKTVASSPLQAAIIPTPTPPLELMRQESSNSGGNHSSDSSPPMSPPPPLGNVDDLATFHDLFYRPNISRNVSNDGATPARINGIPWDVASAGQRGSGLTSIARQLTEELSESRDSLKNSISFRSQSSLSALRQSLYETRTPPADANMRFVFSDLPETASLNTNGERKNLQANILTFEPSVQISEDVELSRASSPTRSPVDQDDDLDTDEFRVGQIESNITPPAISGVSRVSLTGQMAFAIGDDALSEQHNNEDVPPSTAHLTTAHSSLQPPSAGLTRSSYMTTSDGSRMSGLSDFPDPPPQRLTPAHMSLLSSYFDNTITEKEIADVRAYGHVKPATRSRSGSVLTSRPEAQVSRPPIDVPEKQEGVSFDGNEEIDNLIASLSPSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V676</accession>
    <name>A0ABQ8V676_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="709" mass="81889" checksum="18572AB4658C0222" modified="2025-10-08" version="1">MQFPLRDENSEMLAQLAEITEPVHELTLNMMAFGSFTNELSVVLGSNYLSKSETITDSPIIGDEPPLIPPYHSADEDSSLLLRTDSDLLEFFEDGVGDGMPALEPVSDSESDDDDDVLQQQSDTESESEDEGQVESDSEILVSNFNTSIRDDCHTWIDGNLGLWNAPKTFWLQRPLVDETRDVLFTVNESGQNEFSYADVAKDIFGYPNTTWSDFFLHKTIDHGWWPASIDNWMCLAMSFLLNHDAPYPADELWWGAEDSYQFHVNELDDNTYGIEDDNSDYGELTISRTLLLDPSFKFSAWYAQQQAEWLGHLFDHEHWRHRSKPIDDVYKQGLKFVLTHGIPAFPASPFPVITNPFQRFEISKISSPEGVVYQFEDKEARIWSKPLPISILRNTRFNLVGWWKKHLMNYLSEQEQRFEKARISHARKVARANKRRIWNHQKQGKIFALAIEPQLELAQPFPDGRIGVLDHIRQIKIHIQMNDIANPHFRPGELWNQVRNSLARHIPFIPEVMNLGYSSCDNYFVYRDPEDPLQYVIVDDGRNFKTQVSAVLLMTPQFNLPAWYNKRLEKAWNNLMRRIQGPVEFEFLPYLFGKPENDFDHQLDRYVDQSDNYLHLLFGNLEWEERNGLVHVTSLANAYIEPKTYPGLQCNAGVVKDIGRIVPRPIVIVIQIDGRPVRTLVDSGSLGDFMSTHLSDQLRVSKNYHKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6C4</accession>
    <name>A0ABQ8V6C4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_855134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="115" mass="13078" checksum="A96361EA93A77BB9" modified="2025-10-08" version="1">MYIYIPSSPRIYLFIYSFITSLSSVHLLRASLFRNSITEDSVGFAALTCLQAFDHQSDYGPSVGMTRMFRWDRANTLGLDPPLEVLLLLLEVEQVGHHPWIYSGLTSLLCSNYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Z6</accession>
    <name>A0ABQ8V6Z6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="802"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="818"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="853" mass="93861" checksum="1182D10A51B4ECC1" modified="2025-10-08" version="1">MPSAFREETPGKRWLEVWIIGDLFHHHQSQFQLHSLYSAGYLERGVEENFAFDAHDTSYFNIPSCIGFLFRINRCMFWSDNTRVLRVGSPSSPHDEFSSSTSNDKTLTKINDEYETYCQAVTPPAAYPSPPQTDIDAVCKIPLPPFTSGLYPHDEEEDHPDASHSTQNTRHAMSTSPIGGALDSPLIYLQHPTPLSPPPTLPTPTALLPPAEEDHGDTLNVVLPSSLLGSSQEYHYSCNSALPFSALEIDQNDQSDSAPPNPHLLSPLSPQFVTGISAIGHVNQSPRSPSDGIGATSLEGSELDRSPLGLYSLLLDQTGIPSFASPSFGMCEEYKCPWTPRSSSNDDGTARYITKSMTTAPHLSYPSPKSSHWPHQIPLYPPSNPPFLSPHISTELPMQSEFSHPSSPSIRYIELNGPVYDGEAPGSQSPSIRTFELPELEEDEDLETGFDSGLGLSLTSFPTMSEISPAPEDSSSRFSSLSQYILPNSPSLITCLPPTSGPISKPTLESDWDTPTSNLSPANFNDAGYDSATPSSMLLLDVNIESSQNIKFNPCRLPSPNTLVESLDSRLSHLPLDSSPSDIPSYADCPEYAVLRAQPDLYQDLLRLLALHRKAQTSEKEAKIREKELVAQVELTDTCDAGEKIVSTMNVAPVKLPSSSSAVFEAEKAEAKATRKREKERRREVAAIVALTLFGGAHDTKSNRSDGRVEVGSTLSQTSTIITGNLYKEPNERTKKKKKITFMSMAQLVARMILRRRDHSPSLMSFARPISHQLLFSPPGVRPRRYTKSPLWQSMTVDSEKKVIEEDMLPESDVKSDEENEGSDDKDDVDLGAGLKLKGFGDRLEWPMTVDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7C0</accession>
    <name>A0ABQ8V7C0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_983229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4478012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="384" mass="43547" checksum="FBE1F2D090292AA0" modified="2025-10-08" version="1">MASKNPTIQNSPHELLRAIFATLTPGEVAECALVCKVWSLPARGRLYEHIDVRKSPNKMTYVTRSAMLCQTLDATPALRSIVHSLCLVSHFPSTILPEVRAVFLQYAAVQSIPSFINMLPHLQNLDKISFHTNISLPPSEHLLILQAFGKLPLLRHMRYFAAFPGPVRKPSQFIQMLNGLPPQRERGPQLLTLDLRNITELGSFRASLEDLEWTFHPRSPLDLTHLRALSVSTYRAAKYFMREVSGTLESLTFTSASRILGDTESQPPITLPAMKYLCIPSETIDISLIANIHCPYLECITLIWQTETDLDPEFMSDSESPLFLIDRCITNRSNYPILKEIMVLVNEEASGRRTDVSQIQKMLPRCTGRAINFELGEWQERDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7J2</accession>
    <name>A0ABQ8V7J2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_886842</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="361"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="576"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="677"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="576"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4478572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="822" mass="91043" checksum="D973FD2A35FD3904" modified="2025-10-08" version="1">MTSVYSSTFSSDNFGLQLWALGGDDEGVQDAIDAGANINATDASGRTALMCAVAGKHWSNISFAHDESFMTSSRLKVVDILLRRPEVSLSTLNAPQDAFNDATPLGMAAWLNIPEAVRVLLRSSLNCVAVDGTDMHGSTPLMYAARDGHVDIVKLLLQHGARPDLRALNHRSAIQYAISHPQVLYLCETMLRQHRLHEWKFTNKNGSPTDSDDLFERAASSLAFIRTFDDLPQPLEASSHSKTTDTILQCLRSNPQELCSTLFPAHTTQTSFFSPLVNNRDRNGWSPIHHCASASEPSVRVLDTLYCAGADVALFTEHEHYTALHCFAFSDHATYAFDELYQYVYHLVHDLRAPLSARDKQGNTCIHIAAEHGYSIEVLRALLECDSSYSVRDLCNAKGLTAWEVAKPQFRTAFSDTNLSRPGSSLSTNTLRPAHYSIESYMEPESIADRKHASRLPTSNHDIFGTATRLIDNLRISSPSIHHDFDIRHTEHLESLVIEMEQLQRTIIDHFQVRMQQVSDVLRDMEDDAHATAVLLESVTHSVDAKLQERGLQSWTRIRMSEDSEITCVSDRFSNSRGLKTKSSLSIPKSLESTASSANGSSTASTEKKAAPSTTSKFVAWIKRKTSANALAKVSNPSPTLLQKDALKQTFTDRGESDLDMMRTSIESALRTSVFPLRAAGRDLESLQESIASARKLLRSAAQSISRADRVLNSALKTRRAMIGTLRKEDDLFIHSNSLSNKSSLASIASISTIASQVSAGNTSFSGILAESDDEETRAIRRLLLRKIDARHNGVLDEIEKTSRWLLVIKDIVQGVKRRTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7P2</accession>
    <name>A0ABQ8V7P2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_772820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="104" mass="11650" checksum="84DAEF04A9E37CD4" modified="2025-10-08" version="1" fragment="single">KLDHILQLNSSNSYLSNFSCCTPGFSDVSDQKLGLVTTWTNVWGVYRDMCLVCTSLRNGSWRGNSMQSYSMLNGAKNWGNWGLIRQEGDDDLALSMIASNFERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V941</accession>
    <name>A0ABQ8V941_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_850013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4472366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="346" mass="39086" checksum="B8696276F4B76372" modified="2025-10-08" version="1">MEEYFWHSAHWALWSNWDLLRRSSNVYTSFLPTSLSRSQIQQGWSSGARWPKMTEPSGRSSPGEINNLLIWEQPHPLIFATYEYRAFPSLSTLEKWKDVVKATADWMAVFAWSNASTGVYDLGPPLYVVSEDTSPNVTVNPAFELAYWRFGLGLAEAWFNELREEVPRDWTTVKNNLAPLPIQNNGTSTVYTVYEGIEPDFWTDPAYINDHPSLVGLHGWLPPTEGLDLGTAKVTMEEVWARWNFSNCWGWDFPMLAMSAARNNDTEKAIEWLLHPLFQFDDVGMPIGGVRVPTPYFPGSGALLYATAMMAQGWDGSDEKEREGGKAPGFPRTGWNVSVEGLSMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V972</accession>
    <name>A0ABQ8V972_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RxLR effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_489814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224912" description="RxLR effector protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="13508" checksum="1E81BF07562DAF25" modified="2025-10-08" version="1">MISHSLSSIAFLTVLALLSGVDSAPVSYTSLDTSSQVRDSSEPNFETRQLGGLLNFFKATSKSEKGIKAATKGAKSGADQNGNSNSNSDNNGKKTQVVAMPMGIATRENEGSMALEDRSDLVSLYELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9P3</accession>
    <name>A0ABQ8V9P3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_841148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4482690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="741" mass="82354" checksum="2AFF949B707744FE" modified="2025-10-08" version="1">MYTLELVALSLSTTLMPVPVEFAAQVSSTLQLGSIPKLDKTRFISSFVDTQRLHTKYYAEEGRTLWNDLVDTARDPSPRSPPQENAVFGLSTPVLVPRIPKVIIVKEPGSKTSTPKENPPKKAKSKAKSTFHAKSGQRPNEHPQNAPHTKKRAGKLSDDDETAARLAERRDKKRAKREIVRPAANANECDNEDSKQIQAATDKKGKRTKASPGLALMHGFTATNVGKNRLTVPPPTLGVFSRGKASNKTHINTKVIRPPAFLETVFLEGTSHRAKSVPNEPLSDNSTSSQNDSTPSTPPKLKTRKVPNPSVRNHSRSPTVSSSSFDNEVTETPIAQAESEVWDIEREGYNLPSTMSPTSPERNQSVVLNTCTLPWALETETPGEMHEKHKREALAHERDRTSQLSSSLAPSQSASQHGLNGRCRTTTPVPLLASKYFMPQRPQNVPDTLAKDETTIPFSSPPIQTHESSLSDYFPHLPVAPNVQANASYHPPHRADDIIYEPYIAPIYAGESPWDPLAFSDPVNFSDTDAPQPPPEIVAPNLTLGISYPYDFYIPPRVDAPPLQYDSGYDVEDANSMFYLDDDGCGHTGWGLQEIVCNNHEEEYPEHGQIYDEYEHFSCQTQQFGAEHENTTDQNWQRDFCSIEDDTLFGMGIDSEEADMLQCPSEEWMEPIGRDRVLSEANSDDSVIGEMPRFLQGRELLLGFGTTSRQEDIVRDWSGYASVAEADVARNLKGHWLPQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAG9</accession>
    <name>A0ABQ8VAG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_868564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="392" mass="45088" checksum="4BA4745F5C8834DB" modified="2025-10-08" version="1">MLASSSTFPPLPVSEGCKDDDPHYPLGLTQEEKQWSDLYPYAERRGYRLRSRYRPGWVGSWIKDGISTSELLMRPTWKYEYEDAEPSTGRLTVIDAIRISDGASVALKLISMSAHINTPDSNEIEILQYLSSPALMIDSFEVFTPAEMKQLSTQGFSNAFIAVFPYARKWNDIPFRLVWEALEFGLTFLHEHNIAHRDIRSENLMMDASSQCFSAANPSDRIDTPVRYFLIDLGSSTRFQKRRLVNFRHGWHKGIPEIYEMDAEGSRVPTRLYDPFKGDVFVLGMILEGFFGKSIPSLRSLFSFMQNVSPHHRPTASEALSLFHECTKPLYASRMNLIMPVTDPSTLTVEDTELDLFTRWMVQFVAFLWGWVDYLRLVSKVLWRGHELRIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBA3</accession>
    <name>A0ABQ8VBA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_838886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4485153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="53138" checksum="C7928BB2CA904703" modified="2025-10-08" version="1">MEILSNIIRYIVWSAPSPPIGISWRLQLTWVSRHLRHAAISDSTLWNAIWFRDDPPFERSLAFVERSDQEVCSLLKALTPHLHHIRMLIILLDNWEPILSVLKWLSDHGKNGNPPLMMERFEIHRTGNPYIWPGLVYRGERFDPVNHNVSLYSLFGGIYIPELKSFTMNGVYIDWANTPSLDNLNTLDLRRIPLELCPPLPRFRQILASSPMLTKLSLDGAGPAGNPTSTQNYSAIDLPHLHTLVLANFAAPFTRSIVAHFTAPNVKDLTIMNFRGENYGPFYEFMIGRFRNIKILTLYTTNCPPDILPTVIKWLDSMPLLTYARLAALEYDILQAFLFDPDTMQAHPALQPQMRTSFGMVEEFTFNEVTAPLQEALDDADREPRLPNPRLNILEVQNIRPQIFAKFIGARKICGIPVKKTYIAKAMISSFNGPLLEYIRQHIEGLMIVDVGAKTQEEEELLNEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC37</accession>
    <name>A0ABQ8VC37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_496802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="260" mass="28064" checksum="9B2F27757AA6B882" modified="2025-10-08" version="1">MPSYFPSTPITSLRLCKIPQTSASSAIPRLLSRIKHLASRCSLSKLRPRSRSMATTTVPNRSSYRTTVPSSQAMVTFTSFGIYNFEAGPSEIIGTNDPTNREATHACPNKSQTSQSTVTSPHIQDTQDSEQYRSNPPAPASQLAKKILARPPSLNGPPGPPIPMKFVVLPPIATEADAEDTSDESVSDAAVSTRTASLSSSTCHTSGDDNSEMDEPTLRPLTVPPWHMKSRRPNVCATAATSLQPHPLYTALDGPMRFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC40</accession>
    <name>A0ABQ8VC40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_442011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="145"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4485160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="805" mass="90496" checksum="A1B604CC7253F0A9" modified="2025-10-08" version="1">MNHEANRGYFNGYDEYGSGFNFFYAYDSNIGQESLPQSRNADPYAEEYPTNFTQHPPSYQVDAGSYGLGYSEAGNPNHWHHDTDIQGDTVSRQRPHLRTFSNRNNHSAGRRDRPTIQPEHIPVPSSTYLRLAEQPSVRLTDSTQTRKLLILDLNGTLLYREPRTRDGYDPYALNESRPLRPTHTRPYMSSFKAFLFHPETRKWLDTMVWSSAQYPNVKDMVGRCFGEEEVKGYAEHVESLADGTESHREGLVALWDRKFLGLSETQYRNKFQTTKNLAKPWALLPLSTFSGPTKMLSEAWDRVENDDVDIETASKSSGVNSGSRLNNTSFLNSLLEENHLTRNDLLSHSALSTLLLDDSPLKARMQPYNHVCVPEYEGKFYARDVRIAEARDGDAFSDDIAVAVERTETSSSEDVTSAGVGKRKRSRSLSPQLLPHNHKKMKRLSPEYDADDLSQHHDHILLAVIGLLEALKYESNVAAWIKDNGLFASNRTESEYVNPTLLEGDLEAIRIVEGHDAELDGLYRNSVPEGVNGVALIAKKKKERWRNNRHSGRDSGVSALSLGSESSWTDSSMSFSESVDLGHGNDIGVGVARIKNEDNEIYPSQSQHTEPASRPNTPDSRDTSTYSGATTQPPSPPNARLRRDLARKRHLLPRQERRDVPQSLPPTLNFMDSIYLYGKEDMSDRLKAEPSLKSSNLDCTRHVDHTVESNSGEKDIFSNPRASPPGLTGKGLNIDISVGLETPPAELSVIENAIAQTSKFQIPIQPLPSLWYQHPPARWYWVRRGVQALKELGLEVIPGVETNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC50</accession>
    <name>A0ABQ8VC50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_837150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045402118" evidence="2">
        <location>
            <begin position="27"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="326" mass="31764" checksum="495B7F1E2ACC5BBE" modified="2025-10-08" version="1">MAKSTGLVRLALSVMLAMTLLTVCLSMPIGMSKLSSPSDEDPALSSTSAADGGAPTSATSALSPAVYPTPTAGLADSNSATASTNASASAGADNGSTLASASSSSEADTSSASSSASSSSSSASASASASSSGDVASVSASASASSDNNDNGNSTAAASASTSSTVGAETSSSAASASVKSLSSADSDSNSTSNAATGSASPDSSSSSSLSSASSPSFAASPATQNHDGVPPLMQPLAQATKSENKTISDHQRWPSAVAAATIDGVVFPQTSKHPRVRAGQLSFMIGQKCKEMKENGYWSNVGDGLQKSFTVVPLILEAMVKTARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCB8</accession>
    <name>A0ABQ8VCB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_837094</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="8">
        <location>
            <begin position="199"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4486916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="416" mass="45826" checksum="6A7FDE1442F65ECF" modified="2025-10-08" version="1">MLRLCTRNLRRNGFLYRPLTRNFSYSKHLLSTKNFSQPHTSPGQQTTETFANSVRPSIRNQVLFFLFGSSSILLYSAWATNIETALVLEKLKSQSSVWQAQSIANVDLRRFQQMELVKGLRSTYKYLNTQAAEIPQLIRPYLNAAYVALLQPYADASEGRRLCWKICLLNTGIWLMWQFQRLQPMMNRAFVHQPLSGLTYTLLSSTFSHSSLLHLAFNCLALEGFGSAATTYLRQAQDKNVPGQLESTSSYHFLSFYVSAGIFASLVSHVANARIRYPKLIAQLSSPVSRTPATDTWASAVAAASSTVGKSATTTASVASASAVTIPGSLGASGAVYSCVTLVALAYPDSQVSLIFPPVTPIGIQTAALGILTLDMIGIYRGWRMMDHWAHLGGAAFGALYFYYGPSVWSHTRAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCV7</accession>
    <name>A0ABQ8VCV7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_413911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="795"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="822" mass="88701" checksum="51E45FBC7EB41964" modified="2025-10-08" version="1">MNIDTRQKLKRNISLDPQQDPPIKKPKVRKPLETRYETPYPSALSESQVYKLPSSIGPYLSPSKFSPIPKAHLQRNHRRTSSTNLKENASVLSSPFPKGKHPQKLKKYGKAAKRTYKKRADPRSNGTPSDSCSSSASSPDRRNRELTLAEKIHNSSISRSRASQSTTNSPAETTTRVRRPSAPTPPKKIDWKDLVPTHPVNLRAAVSGYSQSHFDTDANEFIRPSPNHSQIDFNRPPSQLSLYDYNRSVTYNDMDVDDTASTDQDAFFTDVQGTSTPFKNLSSLSAADRRFGGTVDPVALSGSALLLLQSNIDGQETDTDNDSCGFDSDEAMDDPGRHRSFRALKLASRNKSKSGSGYITPSCDSGDEEMGRRSPWISDSLISPPKTIDWKLVPQHTEDGAYNQVNSGGHMVTDEEDRVSEPALQDLFDNMILNKTAMDAHSSPSNGTESYCVRLPLRTHSLDTAHPLSSNQEESLNPVAPGARRTRSGTIIPGTSAVPVVTSNVPPALPRRTRSGTVVPGNFGTLYPAPLDDEKQNTLGTALSVYGRRARSGTIVYSSSLAPSLPIVEEKNSTESSSAIPVMSQARRARSGSIMAANSIPEGVVANSTVGPTAAAVPRSRIRSGSIIALGNTLGSLSSHATGFIKRPRSGTVVRASADPDPTIVVEKAIDIDNLQKSPADMNTVSVAHLQGEDVEMSLASEDRHNPIPRSPDDPKDLLEPMVFARPVQSSPPHTATLGAVFHVRSSSGLRARAKAAASKAKGLSKSLTGKSGSSKVRVLIGPEAGAAALARARARAERRSTNDDDDFVNAEDLSDDELLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDH2</accession>
    <name>A0ABQ8VDH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_388645</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF45">
        <property type="entry name" value="MITOCHONDRIAL CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="8"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="100"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="199"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4489176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="31290" checksum="B6F09783D93EC70F" modified="2025-10-08" version="1">MATKSNGQATLNELIAGSVGGAAQVLVGHPLDTVKTRAQIAPKGMFKGPMDIIAQTVRKEGFFALYKGMASPLLGIAGVNSLLFAAYGVSKRIVSPYPQLSLPETSLAGAMAGAANTILASPVEMFKVRMQGQYGGAQDKRLSAVAREMWTQWGFRKGVMRGYWVTMAREIPAYAGFYTAYEFSKRKFASIYGSELPVWALLASGSTGGIAYWLSCYPLDVIKSRVQLRQTPPIGTPVQYIAHEAKTVLAESGLKGLFSGLTPSLIRSIPAAASTFAAFEITREYLAELTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDL0</accession>
    <name>A0ABQ8VDL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase pc-bph</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_896012</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4489155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="558" mass="61574" checksum="9806223CB86B146A" modified="2025-10-08" version="1">MHESFTSTLLSTVLHNPLATLGIVIVGVLFTHILLPYLLDPYSLKRLSIPGPPAAALSDLWLGYHSANGHRSEVVHALHEKYGRIVRIAPNHVSIASPDALQTIYAHGNGALKSNFYDAFVSIQRGLFNTRDRAEHSRKRKLVSHIFSQKSVLEFEPYIRVYVKELSEQWSRLYELALKGERGDEGEGEGGGWYGRDGRLWMDVLPWCNYLAFDIIGDLAFGAPFGMIKSCKDTAQIPASGPSADLTDSKSQVQVKEIPAVKILNGRGEYSMSMGVLPPAYRPIAKKLPWFAAGAADVKALAGIAIMAVRKRLAAQEAGTLSVRKTDLLEKLQRGKDEDGKYMGKEELTAEALTLLIAGSDTTSNSTCAILYYLARTPSTQAKLHAELDKAVPDIESLPMTVDDVKADKLPYLDACINEGLRIHSTSALGLPRLVPKGGMTVEGVTFPEATVLSVPSYTIHRDTEVWGDDIEDFRPERWLGLDGDRKELINKTFNPFSVGPRACVGRNLAFLELQVIVGSLVRSWEFVLEHGSEQELHTSEGFLRKPLGCRVGIRRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDL9</accession>
    <name>A0ABQ8VDL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_920634</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4489208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="480" mass="52427" checksum="B3311AD4FCD4CAB2" modified="2025-10-08" version="1">MPDFVQRFGQENPDGSFTLSSSRQSIITSLLSAGTFVGALGQAFTADRFGRRPTILIWAAIFTIGVAIQTATIDSVAQITIGRFIAGLGVGAMSAVVPLYNGETAPKALRGTLLVLYQVQIITGIFLSYVFDLGTHALGGAASWRIPVGLQLVWGAILLSGIFFLPESPRHLLGIGKREEACVVISQLNGVPLDDPLVDELVDELQYAISAENEGGKATWLECFSPVNGLWRRVVNGMMLQFLQQLNGQNFYYYYGDTFFQSAGTQLSPYVIQVILGAVSVVGTIPALWAIERVGRRRLLLIGAAWQAVCALIAGLSGHFTLAPANTPINDLTSRNKQGGDVLIAFAVLHVFGFSMFWGPTPWVYLGESFPLRIRPKAIALGSATNWVWNFLLSFFAPKIAADIGPLILLIFCGMLVVAFIFVFFFIPETKGLTLEEVDEMYRSGVKPWNSTSWTPTLGQRAHEKAIAHEIRNEKEKDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDU6</accession>
    <name>A0ABQ8VDU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_381574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="46323" checksum="0AF8E427F203089A" modified="2025-10-08" version="1">MDFSFDSVVTEASTRPLFDYTSVGSSSSKLQAKPGATEVDVSSFRNDGFSDFTLDLTCLSNPSSPVSSPPTPLASDNGHNILPAPSPTSPLLPQMQASPRTSTETPATPPKANASSITRATSMMRMSLPAMRYIGRGTPIDPGRRSQWGGRKSEDVTEDGMLFSEIHAHSLDSHNYPHRRSISSDWQAVSEPRALSPLHMDIDSALENHTPIFLEPLPESSKIQIQVDSDPTEWESVMKTVLGSSGTPSSSRPRTGDGGTSSSRRSSQGPIPGLPQHPNGFDIVLGLNSALDLGLGLGKGMNFFELGLIPDTGRDTPSVYSLAPESPDHTRPPSAEKASQELDLMENELPEHRPPQKEEQKESQRQEQHSSEDGGSGSTTAETRAPVAVPFEPKAMRDVHRMHWWQKTIFKLRKVQKLLKAPRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEB5</accession>
    <name>A0ABQ8VEB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_380449</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="74"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="365"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="1054"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="479"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="878"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="941"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1279"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="506"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="892"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="945"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="960"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1279"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1292"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1315"/>
            <end position="1324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4491108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1324" mass="150409" checksum="F638AB507D87AFB9" modified="2025-10-08" version="1">MTSSFDLADALERLTSSASEFEIPNERDVSREEAEQLLEAAVEAVAESSDSITDPQVFDLYCSLLKHSEFVPGSVMNKLLDSITSGLSTQLDSARKDIQNEDQQVYRTHKAPLEMYAFLLQWFVQAAEKVKGTAEPSTPVAKSRRGRGAKSVGARAPARTKKSEEWTWFDHVAVTLGLIARLLAQLNTQRLWTTNTEREVFISCITRPAYQVAESEVFMKSLEVKQNFYKVICRAVKNQNHAATAQILLMQRLQYHEHLAEPIAECLTLLAKEYDHTQLGDEILREISQKEFNAQDNKAPRIYGRLLTKFAEDSPRALLKQLSLLLAQLESDAYPMRMAVIESMGLIILDLSAALDGGTAEDPHQFEKQIKGIYDFLLERVYDSNSYVRVKVLAVLTRLSRIKRKFPKQRLKVTKEAVGALEDKTPTVRKNAITLLIELLHTHPYWMVDGGRLSLDVFNEGYAKLKKELDEIEHTAHQRVMEATNEEEDEEGETTKKAKKKKRTEDDMEVDDEDEEPTDDEDENEDEDENTSMPVDEEGQLPSSTKKNKLKPRKSQLNLEAFNDDEAIRKLTSVDTEKLRLQKKYFADGLEFIRQMEGAIVLLVQMLGSKSKAEVLEAMEFFRVAHEYQLSTAETGIRKMLHLIWNKDNNATSEDGKQLKGVRARLLECYQELYFNPVPDISPKEQVNRIAKNMIQLTFDATLADLTSLEEMMRTMMEDDRVHQDVINKLWNIFSVEKHIPKYQRRGAIIILGMLALSKRSVLVDKVDVMLKVGLGALGKADLTLARFTCVALQRLAGTMKKVKGTMPQTKRIEMDSPIFRKMRDVIERPCRSKDWFGLAEQAINTIYALGQQPDGLCSDIIRKMTIRIFTSKTQAEIPPKDLNAMEEDENPSQATSNPPQTDEDKGDAFELAQLLFVVGHVAIKQIAYLEVVEREMKKQKESQKSAGNTSNGPQATDKDGEELDQVTGNTEDEIGDKITEIREHEMLDKDSLLGVYGPMLVNICGSPQKFKNPTLRAAATLSLSKFLCVSSTFCEQHHRLLFKILETSKNAGIRSNIVIALGDVAVSFSSIIDENSNELYKGLSDRDPIVKKNTLMVLTHLILNGMVKVKGQLGEMAKCVEDEEDLRISDLAKLFFQELSTKDNAIYNNLPDVISHLSAGEHAVDEVKFQKTLKFIFGFIEKEKQAENIVEKLCQRFRLTDDPRQWRDIAYCLSLLPYKSEKSVKKIVEGLPFYRDKLYEEGVFERFQEILQKARLTKSKNDIGAELKEFEEILDEARRQGQDDQALEKRAKGKKAQAKKRAKKNARRVPAKATQDRSESEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VED0</accession>
    <name>A0ABQ8VED0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_867947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4488600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="663" mass="74364" checksum="C67DB8E6ECE6E2BF" modified="2025-10-08" version="1">MSARRYKKQKISNSESDVKAPTAPRTCYIAKLPLELLAEILLCTKSPADILALTRCSKFFCRTLLHEANQYIWRYARQNCLRGGLPEPCPRFTESSFAAFVFDAGPCEICDKKVNFYSSFGLRVRLCANCRAAIHNIRLQFNTGPNTGAVYLYSDWSRALQEYLDVSQKPDILEGYIDATLLKKECPDKDVHGAPEQMCVALHAWRKEYVEAQNVMKDVNTKFSRELAAREGLTFWDMMNTPTYSLLMKLKNASLEEIQYLDYKTREAAIAAELVKVVESRSRRAHEAGYATCRRAVEKHYSRLRALKRETPLPSLSSFRELPTIRQIQQSVGQSVKEVDTNLQSQPIQTLVHSELAKFHLEAKNNLAAILGFQDWKTPSSKKLHPSDRLTAKFQCRTCHRVEAKYKDFGSLDYDGAIMHSCSVTLDKSVPQRPFKAARFEKDTKAITAVSSLLEACDISEDEKGSHELLSAIGPRVLCLSCDAQIILEPLDVIGHSHRHESMSLAILPQDEASKIIGDHPLSHGLAVRLTSKGKISLEMRKLKVYLCRHCMQVKPKIMSIPTTGRAAEALAGNTPSTSTSAAITKTSISVNTDDSAPTTDITSKAVADTAIRKVHSPAAKPSRKPATYIFDGLRSHLKELHKIDSVRDEDFICTQELQWPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEP0</accession>
    <name>A0ABQ8VEP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynamin central region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_364527</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF220">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="32"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="623"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="585"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="709" mass="77909" checksum="CA22A27875AC556B" modified="2025-10-08" version="1">MSTGPAGLGSEIVTIVNKLQDVFNAVGTSTASIDLPQICVLGSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLVLQLIHRPSTAHQNGGPPELGKDGDAAANADEWGEFLHLPGQKFYDFHKIRDEIVRDTEAKTGRNAGISPQPINLRIYSPKVLTLTLVDLPGLTKVPVGDQPKDIEKQIRDMLMKYISKPACIILAVSPANVDLANSDGLKMARDVDPEGNRTIGVLTKIDLMDTGTDVVDILAGRVIPLRMGYVPVVNRGQRDIDSSKSIALALEAERDFFENHPSYKGKAQYCGTPFLTRKLNMILMHHIRATLPDIKARISSQLQKYNAELMQLGGAMAEHNSGNVVLSVITEFTNEFRTVLDGSTNDLSVNELSGGARISFVFHELFNNGIKNIDPFDQVKDGDIRILLYNSSGSTPALFVGTAAFEVIVKQQIKRLEEPSLKCCQLVYDELIRILGQLLTKIQAFKRYPALRERFNAVVVGFLKNCMTPTTKLVSDMVSMQACYVNTTHPDFINGHKAMAIVNDRLNAAKPPPPQSDPKTGKLAPGVINNNKDLDVEAKKDETGFFGSFFTSSGRNSRAGTAKKTGGISTPSTMEAPPPIIKPQAALSERETMETEVIKLLIHSYFNIVKREMIDMVPKAITLTLVNHAKETLQKELLQELYKQEVLEDLLKESEYVVNRRKEVISMVQALNKAEEIVAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFW2</accession>
    <name>A0ABQ8VFW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_832045</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4492523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="257" mass="27893" checksum="53046E28597866A4" modified="2025-10-08" version="1">MSRDLATPSSDLQDYYDHIPPAHRISDYNTLSSQNQQNIPLSAVDVTDPEPYSDIPGASTPRTRPHFGDRRGEYAGYVEEKSRDGRRKLWVLGALSALVIAIVLAIILGVVLSRKSSSSSSSTSSSSGNDTISGDPSQFTKDARLKQSFWGIAYTPEGTLYPDCGAELSDVVTDMQLLSQLTTRIRVYGADCNTTALVLTAIELTKTNLTVYIANFPEADDNGEAYDRQKTAIQSAIQTYGTSHIAGVTVGNEFILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH65</accession>
    <name>A0ABQ8VH65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_919248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627:SF76">
        <property type="entry name" value="KH DOMAIN-CONTAINING PROTEIN YLL032C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627">
        <property type="entry name" value="SCP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="212"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="450"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="519"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="602"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="911"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="922"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="986" mass="109241" checksum="7A54CA14BEFFEBE4" modified="2025-10-08" version="1">MEVYTTSFTYPRRSRHIPSSSSSLDFAGPQNTSDTPFPSHKSFTNNQLAEDVSSPESAEQIAKLSMLAMTLHGCHVSYLEIGGRGWNFTVTGAYQHVLQTRGMILKECPIQHRAAIRVTRSEILDSPSSKPALKPDVRRRLDDIASQTLAHIAVVNSPHSLSSRTPPDGISSSAGWSGLETERICELVITGAGDAVDMARVRLLVMLDELSGLHSEMCEIDKKLHTIVAGRKRNVLQSIQEETATNIYLPSPLQGHLGPELSVPPSLTDNLSKSNGTIWITGEFFGVQRARDMLYQMSATKAKSIISRDTAILPRKLDWMVTDRTEDLKSIMHDNATFIQFPPLGSSTSLISVFGDHRVNIQRTIRSIMQLACQFYVGSFWLLPVQFNALLPPPTLNPSQVTNLIKQISLTTGAEVVFKSMCFELHGLEHEVRAAVGMIMELDIIKAFHHEIRFQIELSNEHREFISGKKNGKINKIMQTTNVKIKFETFNDHNFLIDVSGPDSVVLQGLSLLQEELPAEISFHVPEAYHKRIIGVGGRNIQRIMKKYGVYVKFSNAEEFAALGGYNDNDDNVIARTPAKNALNLDNLKQSVMELVNPKDKDFVNETLSIPRRYHRTLLGEKAIFIHDIETKTNSQVRFPDKETASDVVTIFGPESQVQIAAAMLLDHVPFEADMAVPRSSDLPRVVNSAEFGSLVERVKRELQVSITPNVNISTINGTAASEALGDYSFKFRCQRSNTDFLITAREMLEQFLHNHNIRVYPSPTSHTHKRGDSFADAFPHFDSKLLSTAKTHHESADFGRPVHDPDRRLRLASSSPDVKALFNAPAYIYNFEEQDDSQVPYMANSSQDYWTPMPPIGTGIPSSARHTEDALKRGSDSLLEAKIKEQISKPRSLTNRAQSLDLTYSLSRITETSGLPPPESPSNSGNETGGNSSPISATAPSFPSVYGGRPAVIGTSAQRGSRTIEFDNEDAASDGVTRVMHNLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHA9</accession>
    <name>A0ABQ8VHA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_895485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="55"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="372" mass="41440" checksum="DC7B9759155248AD" modified="2025-10-08" version="1">MTLGGPFTAPPIPGSSPFSSVTPITPNQRYRGWLSEIVEPLEEFIDEPIDPRDYYLDLTEVAEGESGSVYAARISDNANLARLSKLSPLIKARDVEGQANGETMFVAIKTVPILPSGSAKLDELRKELNMIRGIMHGNILGMHALYVDSVEDSLWIRMELMERSLADVVVLCEEGLVLQERVIARFTHDTLEALQFLRTHNIAHRDIRSDNLLLNSQGILKLTDFSNAVKVSPNSPIVHDTVGILYWQAPEVRAGPYNALKIDIWSVGATVWELAQAAPPFADSTDPPTDRWPKLSKPEIFSPAFHEFLRLCSEPASSRPDAQELLKNSFVNNTCGRPVVRQLLQQCTAVEKLVSQRQELEEEDEQATLMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHB8</accession>
    <name>A0ABQ8VHB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">ER membrane protein complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_833198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009445">
        <property type="entry name" value="TMEM85/Emc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19315">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06417">
        <property type="entry name" value="EMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017207">
        <property type="entry name" value="UCP017207_TM-p85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4491786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="177" mass="19112" checksum="13980932A832FCBA" modified="2025-10-08" version="1">MSSGLNLKYSSLESTSKWRNLPPPPGFSKTTSSSKGISKAIAISSTTPEAYDQLKDKRAWDLAISPAKSLPMQFFMLYMSGSGVQIFSMGIIFMLLSSPFKNIAGMNEAFASFAPSASKNPKSFSTMALQKLAYFACNLLTLGVGLWKCRSMGLLPTGTGDWLAFETRGPAPELSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIN6</accession>
    <name>A0ABQ8VIN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="598" mass="69339" checksum="A2FADC4DD29D4791" modified="2025-10-08" version="1">MVRISGTSTPTVVGTTSVAAHELYELKNNFEPPQKLCETGQSARFKPPAAATRKTRRKVPKRFKLIRGKFAILERLVRDVPLEIIIEARITIFCHLDPGDLLRLSRASKGLRNILLSKTSESIWRFTRQNFIGGLPALPMDLNEPQYARLFFDMSCYVRRFTDEPDIFLSGILDTAKESYNYIYDQHTATKMKSAFMGLKTEEDRLIWVNQKREELQELESHARLCEGWHKMFLEQRHEETKDIRRQRMQSILNRLDDLGLRKEAQHILSGASEIMTSDKLTNHPLVKQTKQLTDRGWTSLETHLVPMLTDHKIIRLKKEHHRICRERYSWFEQEYIDILSTHDLREPYPGVGDILTDAIIEDLIWNTALKDEMSCVFFRAVLSENLPRIIKQFRSVKVQEILVIMRKSQPSANISDLHLATTIFGCTRCGVRLIYLQIFYHRCCHMTRAANTRSHERMQVYDAFYETVEDGRWGKGPWSSRFLFFHAQCSHLMEQIVAATGLDPAIATSQDLTVAHPMIERPNHHENGSERLFMTWPAALTYKGVAQNGMPLVMNCFGKKIHKIRAQEPLSFDECFCCVHCHEELVPRQISVRPGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIV2</accession>
    <name>A0ABQ8VIV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_827898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="8122" checksum="291A41CF02A7D4D1" modified="2025-10-08" version="1">MEIMATHRHILAISIVLPLRLVFFWCATILIDRLLMTMGGKSCQWCGMRNHRVHEAASGTLNLRPFSPSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIY4</accession>
    <name>A0ABQ8VIY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">EI24-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_275147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21389:SF0">
        <property type="entry name" value="ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21389">
        <property type="entry name" value="P53 INDUCED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="311"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="40974" checksum="C48565FD73B675B0" modified="2025-10-08" version="1">MSSSTPSRYNPSARSLYPSFLSVQESLILQLKWVKRGLVDAFRWDHVISTIAGDSEVRANVYKSLLLNLLSLTSIYTFDLLLLPLVRDQQKWLHRNVGWFYQGLWLFPVIGLSFYLNSSWCNIIAERTFALKHGHRSVAQQQAVTYTGMLKSIATSAYRVVMVFTSLVVSFALGNIPFAGPILGFSFLSWLDSYYLFEFVWIARGMSLSRRVRYLEERWAYYLAFGLPSAALCTLGSGLAGAAIFALVFPFYIVMAMHARPVPDDPYNPVSETDVVRHPSPFIPIRLPVFALVMFLNDWIVKILSVGGGSRTRNVHRRGTSDDAESVEEGEKIQMQTRNATARFNSSRSNSSRINIGRRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJG6</accession>
    <name>A0ABQ8VJG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_323402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="928"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
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            <begin position="727"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="768"/>
        </location>
    </feature>
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        <location>
            <begin position="942"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="965"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1017" mass="111666" checksum="B2A3E559CD99C1D6" modified="2025-10-08" version="1">MRKKILKKPEPKGTTCVTHVTARDQILAAVGTSVTIRNYSCRPAFRYFLHQCGETSVFFLQQNWSILPNFHVTLSIEMVKNRTSLNPNQQPSVMSPPHPHTVTIVAEDDDDNDICPVCDGQCTCSNNTSSFYQQAPPTTRISSPAHDPPRPILKIKLPPNLLKRKLPPTSKTASGSSSLPYYSAHDTSIQAQRIPKRRGRPPKKLVSHSGPGVAGPSTSVYQRPKAKSVASQNRSLQKKTSKSAARDSDLRKRATKKRKRVDSSHESSSSELTDLDLYTSNNSYHRSVEDHDDARSVQFPTFVSALSSASSASSSDTDSLSGFETDSSIEAEEENFILTEERARVRRELLNGSGEESLQKRRDPNWVIRPRQMSVDAPSDVDMDEDSEATEDDDDDDEDEKEDDDEPDGEDTEDMNTRRHGYVGLVSAWSEEEESSFDADLFFANLSDKESGSSGSCTQSDDGEDGDYSDSELDLSQTASTLIPHLRQGVGIGIPNLAFELTEGWDGQVVFTNSHIESSSRDGLQSLLEATFLPPGPDTSPSPGPDGDVDMFSTDADGEADEEGYEQDVDQDTAEAEYEGDTTDEELVGEDDLPNELAMSLFNTPFAFSNAPSINPMSMISPSSSFRRQSDFGLESPHPSDILSQSMTWGTNDLEERFEGDEPDEEEENTFICEQRNKDRAARGGLPRTGFFEAVEQARQIVIDGERKEIPSSYPRFTGRKGKGVKSKSLSISRGGRSGGSESIQRKLFRPTSLPPPSTRSSVLSTSVFPLSPPSEIPEEIMTLGPSVEITPPEFSSASQSEEPIAHSMTIDLDDVLDASFMAASEPTAVSNTDEEYPAGSSVAVSNSDADPSTGQYIKSLNRWDVISVGALRKTGVLTDSTVGRGSDSGPDYTAYSHVMKSSPLSTMLWHNRNGASKHQRSLGYILSPELGPVRDGDRTPTHGSQKHNGSPPFNTKSRKELRRERKVKRKGYGPVNNHKHTHLHHQHSHHPNSKTRSSSSFQRSNSFNSPVPSLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJM3</accession>
    <name>A0ABQ8VJM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_317718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="175" mass="19785" checksum="B894AABE8A33FE5D" modified="2025-10-08" version="1">MSSPNPVVTLEPFSLYISTTQIFAQPGKFHWSFYLTDAYGIATRYHWSERGGTRGVYAEGVHVQVINPVTTYSASYNVALAYFKVTGFNPATPPNIMQQAAFSAFPESYLTVRENRQNGLSCRTWVLQVLRTLITWRYLVRNDYPESIEAVVKARSMQVENSLMTSFTGSVVVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJS6</accession>
    <name>A0ABQ8VJS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyl-D-glucosamine kinase</fullName>
            <ecNumber evidence="2">2.7.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GlcNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_825503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic-type N-acetylglucosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.59" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24007">
        <property type="entry name" value="ASKHA_NBD_eukNAGK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052519">
        <property type="entry name" value="Euk-type_GlcNAc_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43190">
        <property type="entry name" value="N-ACETYL-D-GLUCOSAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43190:SF3">
        <property type="entry name" value="N-ACETYL-D-GLUCOSAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase BadF/BadG/BcrA/BcrD type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="359" mass="37957" checksum="8CF1CD45CB4E82C5" modified="2025-10-08" version="1">MSLYLCVDCGGSKTSAVVSDTSGNIVGRASGGPSNIAYLTIDSFIETIRETVGDALKTCTSPASVDTVALPPPAGLEFVAAWFGISGADSPSIIESVVNPLSTLLGVPKGLRLSVANDAHLLAAPIRMHEDVISAVTVIGGTGSIVVSFKEKEDGELEELGRVGGWGWILGDEGGGYSIGREAVRQVLIEQDKHSVMKSPPPEGPLRTLLKTYFGIKDVMEVLTEVYVPDPIPSTVVNSEHGAHKYMSREKRLSSLSPSVFAAAFEDKDPLALKVLRMCAKDLAEQISIVVGDASEEAPRLVKASESVICFGGSVVGLEVYRNMVLDDLAAKGHVFKHVEFVDDCAAVGAAGLRLKYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJT1</accession>
    <name>A0ABQ8VJT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_918218</name>
        <name evidence="3" type="ORF">C8R41DRAFT_925864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045031121" evidence="2">
        <location>
            <begin position="24"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4496639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="28313" checksum="50E6D6DE5D270D91" modified="2025-10-08" version="1">MRSAFKTILIFFSLSSIVTFSAAVDCPTADKNGSPLVAPGTDAGDGFITCTYQASGACTYFGQNGEFSSGPSTCPKGFAQGSGATTSSTEQQISTTSKQTPAPETTTSAQVTTTTSAPPPPPSTTSAPPPPPPSTTSTPPPSTTSVTTSKSVVSTTSTTSSSTSIAVTTSSSTAISTTSTTSSSTSIAVTTSSSATAISTTSSTLLTSTASALSTTVLSAAGSSTSGFVTLPSASLSTAPAVSTSTSTIAAPSTSTTSATTNNNSAASVLRQGPVTAVIGILMVLGAINLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJT6</accession>
    <name>A0ABQ8VJT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="252" mass="27859" checksum="55CD4FEF935E39B2" modified="2025-10-08" version="1">MVTLLHTVAFRLAVLVILSSVLGIIATPLPMFEALKNPAGLLERRANPEIVNLHIKRGSFEANGSFAGLKGSGQNSILRPNDEFLLLFNQNKGLRAMPTEQLNGDVLPRWKLVECVHKTNSPGLFLGTLNFATVRSKGEVLGHGMSMSTGEIYGETYSGVNELQVYTQVEHWILDNPSIKYMPDPKNQDALHDLYSAVMERERERVVLTAAGHHFGAKSGGNYVLSTAVMEPAEYKGKWDVKELLGKSVKWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJV7</accession>
    <name>A0ABQ8VJV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="100" mass="10885" checksum="C06B0CBA6DA71DEF" modified="2025-10-08" version="1">MVQTSASVDPSSEVAIHFDSETKLFNALQLMGLIGSMISLVAALFSSVLRQATWYNFFVSWIVYCTSYLLLFFAGHAYDGNPSLSLCLAQSSLNHAASPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJY7</accession>
    <name>A0ABQ8VJY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metallo-dependent phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_761268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053828">
        <property type="entry name" value="Nucleosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014485">
        <property type="entry name" value="Pesterase_C1039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF22">
        <property type="entry name" value="ADL392WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21953">
        <property type="entry name" value="NadN_nucleosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017316">
        <property type="entry name" value="Pesterase_C1039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00785">
        <property type="entry name" value="5_NUCLEOTIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046693229" evidence="1">
        <location>
            <begin position="23"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Putative 5'-nucleotidase C-terminal" evidence="3">
        <location>
            <begin position="387"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4496699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="627" mass="69797" checksum="04C2FB573F40BCFE" modified="2025-10-08" version="1">MHLSAALLSVALPLALRATVNACSDEHAHDHSHAHQKRLFPQTQLTQPTRPLEWGDLNIIHTTDTHGWLLGHQHASFPEPNYSGDLGDFASFVQHMKQLAIEKDVDLLLVDSGDLHDGTGLSDGFPAGGIDAHDANQFIKQLPYDIMAIGNHELYDYINTWDMYTNFVPALDGKYLSSNVNITVFDANNNTIDVPVGNRFRKFTTRKGRKITSLGVLYDFTGNDVNTTVQSVADMVKEQWFTEAIAEEPDVFLLVGHMPVSRDNWPTVFNAVRAVHAETPIIILGGHSHIRDCNQPDGRSMALESGRYMETIGWLSANLGSSSDVNTKNNISFSRRYLDQNRVTYEYHSQQSNNSFDTKEGQNITQGLLDLGVKYDLSMLFGIAPQDFTISRDPYPSNGSSLTLFINEAAPYSLTLNNTRANISNIMITNSGSQRFDIYSGTFDKNDQISASPFTDAFMFIKDLPLGVAQDVLPALNAAGADERRKRDLGSVLQERESEMWKRGYVNMRYMEWLDEMDRRHDGAVKRASQNLTLGYVTSDSCPGVGDDTVHAPLASFDIPDFIGSDTPSLSNDSLVDLVFVDFIQEQLLEILNEVQNATTYTDSDVASYTDVLSNVVLGLYAQHAWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKQ6</accession>
    <name>A0ABQ8VKQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_824346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12446">
        <property type="entry name" value="RRM_RBM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034268">
        <property type="entry name" value="RBM25_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="46"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="PWI" evidence="5">
        <location>
            <begin position="505"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="378"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="270"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="69044" checksum="9456C3E6787F3DA2" modified="2025-10-08" version="1">MQPMPNRMGLGLRPPFPSFGQGPSISALAAQQQAMHFVPPQAQKQTKLFVGSISGGVTDSFINELLSACGKVTSFKRLITPANKPQGFGFAEYDEPDSALRAISLLNGVELPALEDGCANKNLLIKADEKTKAFLDAYSSQRMLTNADEERNKQAKARIDELVQRINKESQDAAESGLLDKEKYVIPPHLHDLQEADLPETQRGLVISEIAQFRERAAKREREKMKDGPPFPQGGAPSGPKAREWGKPPPQQQSPTVASSRGKPSMSGFVKEERGVADDGRRTSRTTKTDEELEQERKETRKRDEEISFRDRERRYEPRERVRIATLERAIARERATKEAEDRDRVEMRERLDLWDDDESDELFYLDRSRWRQLRARRLEAEEAADIKSRRFEEQEAENLRRESEDFLARQMDEMQALAEEQRKAGLLLDDGGLVKLNVSLAPAPAKEGGKEKATTVFAEEEDEEEEIKKRKVPLVKLDFSVAESSEKMKERLERIKESVPHDTESLFKAKVRWDGLSDIIIDRKFEPLVKRLMVKYLGEMEEEDLIMFVLEHLKDHKGPQKLVEGLEPVLEEEAAELTKSVWRQIIFESMAYGEGLLTEKMLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKQ7</accession>
    <name>A0ABQ8VKQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zincin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_760593</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11375">
        <property type="entry name" value="Peptidase_M54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012962">
        <property type="entry name" value="Pept_M54_archaemetzincn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15910">
        <property type="entry name" value="ARCHAEMETZINCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15910:SF1">
        <property type="entry name" value="ARCHAEMETZINCIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07998">
        <property type="entry name" value="Peptidase_M54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="47537" checksum="4F1C53D9F7849BFB" modified="2025-10-08" version="1">MTSTSDVCSHSSLTLIPSRSAFDTGFSWSTAQKRAAAVTLQGRAPLNPSNPAQTLFPAPLVLPEDELFLDPKYPAQSLRSWTRSKERNRVTKEKRTIYVAEPPSVDPNLDAIRQWSQPKVPRVTVMSEPRIQEVIDYLTAFYHGVNVKQLPTKLVYTSSNTGKLPSNIGQRHGHIGLNIGNECVRIRTRVSKDFFIQQLNLDDLLDAATSLLPNDAYALLLLVSHDIYENEEDDFACGRAYGGSRIAVVSTARYNPVLDVVQNIDREHSWPASHCSTYVQSCCTQSAKSLRKKRHKKTGTKKELEQSSNDGPGPIYAALAAHRALPSSQSPSACSGLWLARVCRTASHELGHCFGMDHCIYYACAMQGTASLAEDARQPPYVCPVDLAKILQACSTTRKLRYEALLSFCDKYKDVRHFSAFAAWIQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL09</accession>
    <name>A0ABQ8VL09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_792337</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04906">
        <property type="entry name" value="ACT_ThrD-I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04907">
        <property type="entry name" value="ACT_ThrD-I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="365"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="464"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4497092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="547" mass="60369" checksum="D3CB033D25EFB069" modified="2025-10-08" version="1">MPPTATTLEYASEAPKPLVYSRLAKHHLLDNQKPDYLRLILTAKVYEILKETPLVLATNLSAKLGNEIWLKREDLQEVFSFKIRGAYNFMASLNDEERWKGVITCSAGNHAQGVALSGSKLSIPCTIVMPRGTPSIKVRNVERLGAKVILHGIDFDEAKAECARLADVHGLVFVPPYDDPLVIAGQGTIGMEILKQLPDSDNLEGIFAAVGGGGLVAGISAYVKRIGNPRTKVFGVETVDGDAMDKSLAQGERITLPEVGPFSDGTAVRIVGSEGFRICKELLDGVVKTDNDAICAAIKDIFEETRSITEPAGALAVAGLKHYILKNNLIGAQKRFVAVISGANMNFDRLRFVAERAELGEGREALFSVDIPEKPGSFLSLHTVIHPRDVTEFVYRYNKSTAPDRAHVLVSFKVDAKKRAAEIKSLLNEFEAGGMKGYDISDNELAKSHGRYLIGGSQPVPNERIFRFEFPERPNALRNFLLGLRYDWNISLFHYRNHGADIGKVLAGIQVPPSENNEFDAFLKKLNYTYVEETENPVYKRFLHGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL66</accession>
    <name>A0ABQ8VL66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_901720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BZW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11560">
        <property type="entry name" value="W2_eIF5C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051245">
        <property type="entry name" value="eIF5-mimic_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057397">
        <property type="entry name" value="HEAT_5MP1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043510">
        <property type="entry name" value="W2_5MP1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208">
        <property type="entry name" value="BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208:SF2">
        <property type="entry name" value="PROTEIN KRASAVIETZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25504">
        <property type="entry name" value="HEAT_5MP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="2">
        <location>
            <begin position="254"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="421" mass="47319" checksum="E48D0FF016EDE87A" modified="2025-10-08" version="1">MSTQSAAPKPSLQGVRIKARKGAVKAHAKHEPTVFRDQLFKHLETVPDGDFESFTTKLIQAGSTLEFLKYADPLFEIILVGGLLQPGGSYIDDGAPISPFTIFNAKDPANVEEIKKYIEVLNKLIRRYKYLQKPLETTALPGILQYIHRWDPAQKDKLAMATGLLMAQGLANASVLQSLTKEHLIKNDVSINVLTLIFRAYLVDQSMDHLSGSLKKGGIRDLLAFFPANKQEPKQLEEHFRKADLPQIAEWYAKKQYAMIKDAIVKEVQSLVEHDESPEQIVAAVKAQQGSTPIPDPELIACLWQGLISSVDWSARPDQIEGLALREVGKFAPILEPFCSGPKTEVALINVVQVYCYEDTRIIKTFPQILKVLYNKDCISDQAIIYWYQKGSKPQGRQHFLKSTEALVKFLQEQESESEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLJ7</accession>
    <name>A0ABQ8VLJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_979912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21075">
        <property type="entry name" value="DBD_XPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="160" mass="17725" checksum="4D475B67CEB76DF6" modified="2025-10-08" version="1">MPRSYSSSPTKMSPRSPYAKGNPSNQRLAQRDSGRWILRQDAAKTYKLQLKDLDLIDPIEVQPNPYRRGEMRKYNESDVAALAESLHRAKASNTTMIPVSSTDGGSTVLTPAKILAVPSGPQILRTHALKDFDLTRAQLDTIRPVSVEPNPPGAYRIRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLY5</accession>
    <name>A0ABQ8VLY5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_865600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17963">
        <property type="entry name" value="DEADc_DDX19_DDX25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="109"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="289"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4497281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="474" mass="53218" checksum="406243EE71960F46" modified="2025-10-08" version="1">MEKDADGFYTPAPVAVHAAEAEAKPEANPEAKLEDEEKAEAPTESVNTDLINSTFEVSVTLADQQADSSSPLYSVKTFEELGLHQDLLKGIYDMGFSKPSKIQERALPLLLSNPPTNMIGQSQSGTGKTAAFVLTMLSRVDFNLNKPQALCLAPSRELARQIMSVVIAMGKFTSVQTEYAIKENLPRNATRITAQIIVGTPGTMIDLLRRKVIDASDVRVFVLDEADNMLDQDGLGDQTLRVKNLLPKSQVQIILFSATFPDHVRAFASKFAPNANKIELQREELSVGSIRQFYMDCRDEEHKYDILVTLYTLLTIGQSIIFCQHRHTADRISARMTAEGHHVASLHGAKDATERDQIIDRFREGKEKVLITTNVIARGIDILQVNMVVNYDLPLMNERSSSLPDDVRPDVETYIHRIGRTGRFGRKGISVNFVHDRKTWQQMQQIEEQTGKKIMRIETNDIDVMEEKMRKAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMM7</accession>
    <name>A0ABQ8VMM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_917366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="7"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="29549" checksum="CC3E3F29C52B0C0E" modified="2025-10-08" version="1">MKYVALRVIIERKTLKTGFSSVVLTAFGLDYSEESIEEAKRLVANSDYIYQLLPSGDYDYSRPFSHNVIDKYLSAALFSSTKYSRLLTSKKATIFRSSFPQKPLELELPKAMVAMAACVIHSILQDHAKSVEENFPPTGLHSLWTTFIAVLTNLETASRVNYHKLMHKLYLKSTRFVAPTQHGLSQDQILQRINFAAFAANGGDDSDSSPSELEERHGVLRNEQGIAASMSSSGADSNATFDGREGTLSGEDDEPGVDGEGAEKNGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMT4</accession>
    <name>A0ABQ8VMT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioesterase/thiol ester dehydrase-isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_941212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lcsJ thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="42545" checksum="C60F198C7282C8D7" modified="2025-10-08" version="1">MKVDLKQRWPSLFPALLYSVSSTSARGQSLAKIIFKYLLYAIVLANLRGAPVVWHWRVFWPIIKYNLQFLAFRVPNACATLLNRGERARRIAGYIDKTSPVGVHPFDFEVIYRSRVSVDESDFNMHMSNSSYPKILDFTRTKMATHLFPHFLRAGGVVPIASTHFHFVREIPMLAKYEVRAGIGAWDEKWFYVVGRFVTKQKPKSHNAQQSSSQVPPLTKSESDLVAKLFDSSSEDEEDIILHTIAVARCCYKLGRITVPPSVLMATNGVCVYPHEVTMTELDPTFTGPLDGHSGFSVESPPHTWTHHARNLALDPRKLREFYKGAWRQDPTRWWDSAMGAGGSVEGKLKERLGICKQLFEGMDGVRQFGEPVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN40</accession>
    <name>A0ABQ8VN40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_821165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="140"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="282" mass="31780" checksum="0D487F738C491D86" modified="2025-10-08" version="1">MSWFKTSVTGEEPERYVEPDSTPRVKDPSIPNRMVVDKAANKPFLAYKAYRQKQEKAHNEWLERQKIRQEKIARGEEVGPEERDPTEPEEVGLKGLLKFLFYLVVFAALAGKLLAGSYTWNYESRLAQLKSYIPTDQTLFSESTLAKFDGSVPGKPIYLAIDGDVYDVTNGKAYQPGGSYHHFAGVDAARAYGTGCFKTHRTHDLRGLTDAELRGVQHWKEFYANHAEYKKVGRVNHPLINPASPIPEHCKPPKVKNDGKDGKAKEKDKSGAKESSMVHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNX5</accession>
    <name>A0ABQ8VNX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_819296</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="53627" checksum="792700757F7C3412" modified="2025-10-08" version="1">MSAFSAATHQLAKGTACIDCRRRKVKCGGEFPSCKRCVRGGYGLDCQYVDERGKTGVQLLEASVTRLETRLAELQILAAEKQQVLEIYVPGRGGLRRNAFDQDPMFRLVPPGHAIRPVTSLPDGWWERVRMPLEIAKTLMDYFAPCAFQFGFFMHGPRLCQLMFSQSNFCLLSPNLLNVIYLWGIHLSGDERLLAHEPLFLTRAVTFDLSGQQSQHVVHNIQAEILFVAYFLRLGNVNSAMHRLNSALSLCISYGLHKQASNRPNTALHLPPPRDSIDQGERIDAFWTTFLFYKALDMKHMISLIMDESIDTPFPFEMSAYEGGIVPSNLGGVRTLKSFVNAPGADLSHGALALTAKAAALFERARYYGENGHLVLYPDEQKFEEDLLFFIESVPPLSQFVGPYTKYTWITVVTLLQVAVIHLHGSRKYNASNRKCLDAAQMAANLIASFNHLNNVQYIHPIMAVRLHVGLQCIHSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP83</accession>
    <name>A0ABQ8VP83_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Sulfate adenylate transferase</fullName>
            <shortName evidence="7">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MET3</name>
        <name evidence="11" type="ORF">C8R41DRAFT_163545</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. Dimer of trimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03106">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027535">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050512">
        <property type="entry name" value="Sulf_AdTrans/APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004040">
        <property type="entry name" value="PRK05537.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="10">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="9">
        <location>
            <begin position="176"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="APS kinase" evidence="8">
        <location>
            <begin position="397"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Required for oligomerization; adenylyl-sulfate kinase-like" evidence="7">
        <location>
            <begin position="397"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="199"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="293"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="site" description="Induces change in substrate recognition on ATP binding" evidence="7">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4498189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="576" mass="63980" checksum="AE76B2ED9198B1F9" modified="2025-10-08" version="1">MANVPHGGVLKDLVARDSQISSRLRDEAAELPDIVLTEVRQLCDLELITNGGFSPLEGFMNEKDYKSVVDDLRLADGTLFPMPITLDVSKGTLDELKIAAGSRLVLRDPRDDEALSILTVEDVYRPNLVKEAEKVFGADDPAHPSVAYLRNRVQDFYIGGTVQAIQAPNHFDYVALRYTPAELRSQFKKLAWRKVVAFQTRNPMHRAHRELTVRAARQRQANVLIHPVVGLTKPGDVDHYTRVRVYEAIMAKYPNGMGHLALLPLAMRMAGPREAVWHAIIRKNFGATHFIVGRDHAGPGKNSEGKDFYGPYDAQDLVTKYHEELEIEMVPFQQMTYLPSTDEYQPVDEVPKGVQTLDISGTELRRRLRTGASIPDWFSYDAVVKTLRESYPPRDKQGFVIFLTGLYNSGKDTIAKALQVTFNQQGGRSVSLLLGENVRDESSIDKSYTLEEQRENAQRIAFVSAELARAGAAVIAAPVAPLESTRQSVKDTVLHSGGAGGNFFLIHVATPLEHCEKTDRRGIYARARKGDIKGFVGVDATYEKPERADLVVDVTTQSIPGIVHSIVLLLEASSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPZ6</accession>
    <name>A0ABQ8VPZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_894578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045868469" evidence="2">
        <location>
            <begin position="25"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="995" mass="112848" checksum="3651941BECC0CA88" modified="2025-10-08" version="1">MHLPRSVFSLRQLDLFLWLLRVNGVEDATSIKSMKDLDMKLQSLYGIQTFKYKGAFGHLYYVNSLADIISQEISQNVSEARQFARWLHEVPDEDLGPMARLGPPGRSHDYYIFEPAMLRSAFKRQGKLYAKCWKLKANVRQDSSKGWNVIKGNGEFVVNEDDHSPNATLLGILDMTTTPPTLTEWKLTDPLVGNKWRQKANGAECLSFPIWLYCDDTSGNTSKRWNAHNSFLFTAAGLPRSEISKEYNVHFLATSNSAPTLEMLDGIADQLQDCQENGIWAWDPKTQSRVLLLVSVLALLGDNPMQSEFACHIGLRGKLFCRTCWIKGKDAKAGNISLPDEAPADNSDNESETGSAASGSTTASKGGKKKKQKVFKESLKTMYDCVKAFVKPAKPRNRDETITAIKTQFVHAETVGTAKKIKEMRTESGVKDTYQLFFVNRLLKRRQNSNAEPLQASQSTTDNPMSPVWRIRGLDPHSDTPVEILHVVLLGFVKYLWRDVIDNQLKKNVEKKKELATRLSSVDVAGLGLDSQLTGDVLVNHYGSLTGSDFRKICQVAPFVLKEFVTDECYQTWLSLSKLIPLIWQPEIESLDSYITLLEHEIEQFLLHAAKWSIRWFNKPKFHILVHLPDHIRRFGPAMLFATEVFESYNAVIRAKSIHSNRLAPSRDIAWAFARQNRIRHMLSRGVFLDHADKKFEDTTLLQKERITQVQQYFRNGSFAQNHWVQVGKSASDVVSWSDNIKKYLGTFVQDPSSLLQKWGNTQTGRLVPETPLYTVHEKTYCTFHRAKTLRAANSDKCLPLGFVACSDPKLHTFAERGISVVRLHEALGCKRDAFPIQNIDCVLVQGMKVSKEASSHGMPRLSASGEYFAVPPSSIQCSLNVQHDCTRNCCKIDGKIRVRQEQQKTMEVKDTVIHTGVLEDWVLNTAQMRDTKYLQRFRIPAKPLVLEYVLEQSATQEWALQNPRKPAQTETPSLPQICIKRTVIETQIDSQSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQU9</accession>
    <name>A0ABQ8VQU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="274" mass="29251" checksum="4BCB3AE83C8296A0" modified="2025-10-08" version="1">MSTTLSASSSMITYSHHWSSSNGSMGTNNVGATANVTFNGTFVQVFGTIPALKRNTPGPSSSYMLDDAPLIQFNAARFMESDEVNNFAFYQSSLDLASGNHSLVITSLTNGADFILDSIVFSSDLTATSPIASETPKPSSSSSSTSSSGSTQRVSGDPSKANVGGIVGGTISALVVLAALIAFFLVHRRRKQRTAKRREVTPFVPERNDSPFIAPNYSQDSYLVSSPQPRYDEKEPLPRMSPGLSSLVRHGSMYKPRPDSDNLPPMEFGYGGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRM8</accession>
    <name>A0ABQ8VRM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositolphosphorylceramide synthase subunit Kei1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_817041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013862">
        <property type="entry name" value="Kei1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077:SF1">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08552">
        <property type="entry name" value="Kei1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="312" mass="34814" checksum="927CCECF9CDF9F5E" modified="2025-10-08" version="1">MKLTLKPEWRLWPLSSFLGVLDLKTGVTIALLFAVFNKVAGVYGLIALATGAGGSFSQFSLYLYSLFALFALFYGLKAVGQEDPKNTLYFAHFFFADHVFSTAWTVFFAVVWWFQTPHDGRRMANSPAQLQIINASPGYHNMTDAQRELAAEQVWNHEKGTALAVIILSWLSKIYLALLIYSYATHLRKGSYRSLSRTRVPGAASPNYDAGLGYPDDEEEETEDFYRLPLRTPNTGNSISSFADFINAPAGRARPQVPSMSKLNGSVNAEEEEEVLFDEDEFSRGSSSRGHTKMGTDESSAEEERHGFGRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS13</accession>
    <name>A0ABQ8VS13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_87492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="1">
        <location>
            <begin position="132"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="294" mass="33856" checksum="64AA577F7BF5EA6B" modified="2025-10-08" version="1">MATKVVEVAIEQYDPVELEPIVSPPIPLSDWKAWSYYARPCVNGVEVDNLSPSPDLDVELDIQEMFDYLKSPGGTPHPERWIKGQKHIALPPRPTRWKRVDPLEPIPFPWEIQLNPLLTHSLITFPDLTPIYWNLTFQATILFFLTEDGGLQFVLDNDICQPATYPLVTHMYVCAFAFAPDWNTQYKLPWPIMLQSRDGITCDDFFVGIHDNFQQHMKKSEYEKLGEEMQRRAMSAHVHNLNVNADNFMKRVDILGDNVFFRGLAPSMNMEGWVLLLGTEPPSMIRPRPGLDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS79</accession>
    <name>A0ABQ8VS79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Shieldin complex subunit 2 first OB fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_894625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049507">
        <property type="entry name" value="SHLD2_OB1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21669">
        <property type="entry name" value="SHLD2_OB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shieldin complex subunit 2 first OB fold" evidence="1">
        <location>
            <begin position="173"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="35522" checksum="22DA99C5E9A3510A" modified="2025-10-08" version="1">MYHVFLGAPSAKSLSESSKENLQYTWTKVCSPQDVTNGPPLSLSLPYSLPPPATLEAASRRISLMYQNAIFQDTESEQETEELQEEDASTFITWPPTPMVGEENAKGSIRLNNSRSFINTTTRLESQLETQETQESQSLNYSDSSSIARFPKFHFNLHSITSLAAIRKSGKTESGSTKVNVLLAVLEVEGPDTIRTKKGPDAGKEISILKMILGDEDGSLSKLTAWRETANVWGGSGPKDVAAKRGDVVLIENVTASHDPSTSPTLTASPNLKSKLQICYRTMPYAHEDMQLRPDLRLGGSDASVRKVASLVRWFERMAGLVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSC6</accession>
    <name>A0ABQ8VSC6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_815091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10874" checksum="74F3F796086FF889" modified="2025-10-08" version="1">MQKGQLRWFVHFSHFITSLSLMLSPSTPFPSAQVSTCLDKFCWQNSSQFTIYHLCFHLVLSSPVYSYWIPALVTSCNSLILLVMYSGKHVRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSI2</accession>
    <name>A0ABQ8VSI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SBDS protein C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_815343</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDO1/SBDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="entry name" value="Ribosome maturation protein SBDS, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.900">
        <property type="entry name" value="SBDS protein C-terminal domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018023">
        <property type="entry name" value="Ribosome_mat_SBDS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002140">
        <property type="entry name" value="Sdo1/SBDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039100">
        <property type="entry name" value="Sdo1/SBDS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046928">
        <property type="entry name" value="SDO1/SBDS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018978">
        <property type="entry name" value="SDO1/SBDS_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037188">
        <property type="entry name" value="Sdo1/SBDS_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="SDO1/SBDS_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00291">
        <property type="entry name" value="RNA_SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927:SF1">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20268">
        <property type="entry name" value="SBDS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09377">
        <property type="entry name" value="SBDS_domain_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="FYSH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109728">
        <property type="entry name" value="Hypothetical protein AF0491, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01267">
        <property type="entry name" value="UPF0023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS N-terminal" evidence="8">
        <location>
            <begin position="14"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS central" evidence="9">
        <location>
            <begin position="109"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS C-terminal" evidence="10">
        <location>
            <begin position="174"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="27742" checksum="E675FD8480EEA443" modified="2025-10-08" version="1">MPINQPSNQIKLTNVSIVRLKKGGKRFEIACYKNKVQEYRNGVENNLDDVLQISNVFMNVSKGEVAKHGDLKKAFGTTEISEIVSEILKKGEVQVGEKEREHDQSALRKEIATLVAEKCVDPATQRPYPVGMIEKAMSEAGYSLKPNKNAKSQVSDCIKSLQSDSTLPIQRARMRVRVTVPNVDSERLRNKVSEGAEKIEEEIMGQNDWEVILLIDPSQFRVINELLQKECKGKGRIETMAFAAATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSS2</accession>
    <name>A0ABQ8VSS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_815674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="124" mass="13721" checksum="595F9F96CB507495" modified="2025-10-08" version="1">MLPLLTPISANRHLQIAGEPVKPPRRPVVKFRDMTRELQNGGEVDSEHEDSSDEEDVVECRVLDWEVSDTAFALDEDIDLAAPVLRDMISETGPPIGEQSNVKGKASSTTFQSPSKPDVPDYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU75</accession>
    <name>A0ABQ8VU75_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CcmS related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_753017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058258">
        <property type="entry name" value="CcmS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26617">
        <property type="entry name" value="CcmS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CcmS related" evidence="1">
        <location>
            <begin position="44"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="217" mass="24631" checksum="3EB28B429FEC829A" modified="2025-10-08" version="1">MPSKTLAHAYNGTTTSLNTGLPRNKINEYTNVQFHESKGAALMPAQQALFGRARKAKDRIHWMFPPNKDERVESLLAWIETVSRDLGTYGLHKFLQSRERGALIANADYRIPGGKNEPAFDWLTFDHLQETRDKIMQESAAFYDPTAQAIIFVFLPSQSGNSVAMWRRKINVPNNMRLMLQAEISLALAALRREEDYVVHVDEYVATSGALFPGYRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUM3</accession>
    <name>A0ABQ8VUM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_527632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045199690" evidence="1">
        <location>
            <begin position="25"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="22466" checksum="C9390AC281D27090" modified="2025-10-08" version="1">MQWKFHFDHPVLLLLLFYHRANIGGYITGRSSGHDDAVIYSRTMEREVGSNYKVSGLCSLRKHVIVRGVKNLFLRAPTELPYSDMGRYTPDPKVFGIPLLEEYIKTTPEYEMMRPHTKHVVVQYATAAFMLGERVAESVPSRVIYVETKEGPAPCVVLASDKEHAASFSTEEGREKLKKVYEIIRLEQPPAWYRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUU1</accession>
    <name>A0ABQ8VUU1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_56618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28497" checksum="B833942C0533C0F2" modified="2025-10-08" version="1">MHSTSSVVYLPLKGNDSEENIISNSHSRFSFRTLIVPCLLLVLAASNLALLTVLWLKTETTASQVLYSPAEDAIEYKTVKFHSGFGADLPIYDRPPSPEVDAAWASLYEFALNKVPRNEAILMTNQTYPVLGEEGYYMIALDVFHQLHCLNEMRKAMYPEYYPVSGEGIHTPHMQHCISSLRQSITCSADITPIVWQWSNKSKAAKERSDVVHTCRDFQKITDWAQDHFVPRQQNMSIFIDDELDIPIIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV07</accession>
    <name>A0ABQ8VV07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_812265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="93" mass="10427" checksum="A80F4588ACAB3EDD" modified="2025-10-08" version="1">MCVPDNSFSRYSIYQSEIGVYALGGALSDSGLFDICLQYGDPSGSLRFFVSTAPNRPPTRNEPEYPPDNNYYSSRYYRTASPFFVTLPLSNCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV30</accession>
    <name>A0ABQ8VV30_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA replication regulator SLD2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_21415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Has a role in the initiation of DNA replication. Required at S-phase checkpoint.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22289">
        <property type="entry name" value="RecQL4_SLD2_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021110">
        <property type="entry name" value="DNA_rep_checkpnt_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040203">
        <property type="entry name" value="Sld2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28124">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28124:SF1">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11719">
        <property type="entry name" value="Drc1-Sld2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="44"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="549" mass="60664" checksum="7E562EE0DF2A599C" modified="2025-10-08" version="1">MASGDVALVRGEVKAWERSFYQENGRNPTVDDIRANQQIANKYRLYKKLSKATSSVNPDSSRRSSSTRPSTPSRKTEPSSSVISKSRALETTSALSTYNPFSPQKNKEKQKAPVGNVSLIPSNPFATPSKVKAKARVREPSPSPIHETVPALSTLRPSASETPVGIVRARKRLRGEPVSPSPNKDKRRRMLSRTNMSRRDSGSSDSRQDDEEAGNSSFVVDSPVKGSSSKSFMSLFEDASTDPKVKTALTRTKSTSASVGLFGPLRSQAVPFEDDFESILGPVEGKLKSRLRTAANSIPFSSGLVPKPKKDGLYSMQDPRPQPYHAHTVEKYSINDRISRKRQSDSESDSEQLNPNPLTSATILIPPSPPREAPSQRSVDLSSSKGKGKAFFRKRTKLEDDDDMDSLSANVKVLPIVSRPSRASDEDHELDAGPEFDSVHWYNRRVGPPRVDNGEHTSDTFEVDLPEKLKHVLAFSSSEIEMRHIQEEQVVESLLYGRRRGHYEPSKGGEIWDVGDTDAVGLHEEASDMKAIADEDWEGEPVPWEVGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVP6</accession>
    <name>A0ABQ8VVP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mug135-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_811536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0612 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013902">
        <property type="entry name" value="Mug135-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08593">
        <property type="entry name" value="Mug135_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mug135-like C-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="61" mass="6813" checksum="892340B68F92524A" modified="2025-10-08" version="1" fragment="single">MVSGCHLLLFIMKTGNVPSPALNLPELQNINVLNDLTHDQASGWYQHYFPEGANESRTVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVS3</accession>
    <name>A0ABQ8VVS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calcium-activated chloride channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_956582</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="29473" checksum="9FFC57DE024A3F3A" modified="2025-10-08" version="1" fragment="single">ENHTHHSSYNFFLTLKTFIFTALIAYLGPALSAFVYVPFGEGLMRIVQARLFDRFVPHTGSHYTVTNQIVSTFVEIGILYVLPKITAFRTKKADLSIGTGSLLGKRKVVFEDEKGKGGQAEKEFLDQARAEAASPAYDAFGGYSDMVIQFGYVALWSTSWPLPPVMAPLNNLLKLSSDVFKITVHEAVRTDTTGPWFEALGSLSWHPLLFITQNPAGPTSLCTTFRPSSTDACIWIHHVVVFASSSSGVVRSMTQSDEDAMVHKSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWT5</accession>
    <name>A0ABQ8VWT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_977308</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd17936">
        <property type="entry name" value="EEXXEc_NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041627">
        <property type="entry name" value="AAA_lid_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050773">
        <property type="entry name" value="CbxX/CfxQ_RuBisCO_ESX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392:SF2">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17866">
        <property type="entry name" value="AAA_lid_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="486"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1334"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1611"/>
            <end position="1768"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1887"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1253"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2119"/>
            <end position="2222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2296"/>
            <end position="2330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1162"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1253"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="2141"/>
            <end position="2151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="2164"/>
            <end position="2174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2199"/>
            <end position="2218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2296"/>
            <end position="2329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2366" mass="264345" checksum="96AF5887D09E6797" modified="2025-10-08" version="1">MVDQNRVAKLDKLLGNVLNGKTTISTPTQSKQFIEAICAQADHAGCVDRIIAAGQQGLGAIQASLRTDLSSVFFDGPATTLLTYLQDPTIKAISGGRFLEKILQAIVDPPIFWTPFVEAFRNRGLSEPTQKCFSWLLLQLMKSSTDATSPYLPIALDVEPLMAKSHILDVRNFSAGIRNVISVLSAPPTTTTTTQEDHPPGGRHVNDFKDFRAIAILPTSDEIACATSPFLRVSSALDDPDTEEFREAIYLDHFFRLTREEMINEMREELQLALGKQPRKNRRGLTVNGMKLVGVDIGGDERRAKWGLVFECLEDWPQLASLDSEKRISFFKAKENQKILKNGSLCVFVIGDKAVAFPTIRRDETLLAKKPPRIVLELGGESAVTELLLKTQVTTDVRLIPINTAIFAFEPILNTLKRMKTLPLVDEILFWNPDKPLRGPSYPFPLEQAISNISRNPQTDVGAMLELGKKIVLDDAQAKSLLSGLKQNLSIIQGPPGTGKSFIGALLAKFLYEFSDHKILVVCYTNHALDQFLEDLLGVDIPENDMVRLGGGKTAERTQSMLLRNQPRSYRFSKGDNSIITQLKADGELRGLGLQRSFDSFIQSSVGDADLLVHLEFEEPEFFEAFSVPVSEDGMATVGKGGRAVNEFYLVNRWRQGQDAGVFQRQQNILNSTHIWNIAKADRKALEDKWVQEILTEKIDTLYKQARRYNETQIELEQKFRERDVAVMKSKRIIGCTTTAAAKYASDLHEVGINVLLVEEAGEILESHVITALSSSIEQVILIGDHKQLRPKVNNYNLTVEKGDGYDLNRSLFERLVLKGYPHETLVAQHRMRPEISAIIRHIIYPDLVDAPKTLNRPNIFGLQDNVIFIDHSKPEGDNGSISDKRDLGSKASKQNFFEARMVLKIIKYLGQQGYRTDDLVVLTPYLGQLSTLQQELQAETDPVLNDLDNFELVQAGLIPRSSQNSNKKKLRLATIDNYQGEESDIVVVSLTRSNSNNDIGFMFAQERLNVLLSRAKNGMVLIGNSHTFTHSRKGHELWTKLLTFLREHKHVYNGLPVVCQQHPQRKSIIVDEAQFDVDCPDGGCSEPCGSILSCGIHQCPLKCHRIGDHSTVFCSTIIEAQCLKGHDQSRRCSDPPPTTCKHCDRIAKSVQAQKDKELKSRMKRQQEEQEHHKQLKELEQKISEQQELARDAQSKRQRDNELWQKAADVEEAKTLTQRAISLAQQIKQQVFPTFTTASTDPLKSPQPLIQRATTSSDTTQRLPAVLTSPSSNSKLSSESEDRWQYKKNIEGVNNQAVDAIMKMTGLEKVKSEVLKILDSIEVKQRQGARYDDERYNVAFLGNPGTGKTTVARHYAKYLSSVGVISGSAFEETTGSKLASDGVKNTEALLDKVKNAGGGVIFIDEAYQLVSGAYGGKEVLDFLLAEMENNIGRLVFILAGYNKQMEKFFEHNPGIPSRVPHTFHFHDYSDDELRLMFERKLHEKFDGRLKVEAGVHGLYGRIAIRRLGRGRGREGFGNARALENLVSIILKRQASRVTKERTSGTRPDYLQLVKEDLIGPDPATAILQCGSWTKLQELTGLSSVKRSIEGLYDMIWRNYARELNEEEPLQMTLNKCFIGSPGTGKTTVAKLYGQILVDLGLLSNGEVIMKNPADFIGNVLGASETQTKAILASSVGKVLIIDEAYMLHTGKTNQSSDIYKTAVIDTIVAEVQSTLGEDRCVILCGYEKEMRDMFQAVNPGLSRRFSIEDAFKFEDFTPDQLIEILDLKLKQQSLGATDDAKKVAQEVLNRAKMRPNFGNGGDVENLITKAKQNYVHRIRGSLVPRDASIIFEPADFDPHFNRVHDSNKIDELFKDVVGCEGIMDKMRSFQKVAQTGKMRGEEISDLVPTTFVFKGPPGTGKTTTARKMGEVYFDLGLLSSAEVHECSASDLVGQYVGQTGPRVQDAFKRAAGKVLFIDEAYRLGQGHFSQEAVDEIVTLLTDERYKGKIVVILAGYSEDINQLLSSNRGLSSRFTEEVIFNNLQPKECMSILVNDLAAKKVMLAGIDDATKEIHQNVLELLNEFISLNDWGNARDVKTLAKKMIEKTFVRNVTIGDSLVLSSEDALDVAKDMLADRRSRMVVSPGSTRRKGTDAPVQLAPVVPPQAPPPPSVGTNTATSAAPQKRQRERRRQPKKAQQLTKDTESDGSGSSAPKQNPRRNADEPKHVQSGYDARRDSGVSDEVWAELQKAKAEQEANKVRAQKKLDAAIKAAVDAAKKAAEERRRVQALAEKIKKEQDRLKKEELERQRKEQLIKEKEAIRRRKEKEERLKAEKEAQERAKRKEEEAQKKLQQMGVCVAGFRWIPCGTGYRCAGGVHFVSNSELQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX00</accession>
    <name>A0ABQ8VX00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_809335</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF85">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G00710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="512" mass="56638" checksum="68538CC8C418B7A4" modified="2025-10-08" version="1">MSARKAESPSTSSSQLKGQSMCDHVEDMKLSNYDNMGEADLKKLERQAVRRLDFAILPMMTMFYLLSFLDRANIGNARVAGLQKDLGMSDQQYQVCVTILYVPYICAELPSNLLLRKIGPRYLMPSLLTLWGLMVALQGLVTSYSGLVVVRAFLGLVEGPMFPGIVLYLSSFYTRSELAFRVAVFFSSASLSGAFSGLLAAAIINMDGISGKPGWAWIFILEGIFSSLVGILGFFLIPSTPQDLKFITPQLKEVLIRRLEKDKPSSMSDEDHFSFKEVFRSLKSPHVLLVFAIFYMEGTVLYGQALFLPSIVNQLGFSANKTQLLSVGPFAGGFIVTLTASLFSDRIKSRAIPTALISILGVIGFAIYLSSEEKYTRYGSLFFTVPGVYAAVPPVSAWMANNSEPHFRRATSIALGFVATNAGGITSTWLFPTSEAPRYRKTTIINLTFTILIIVGAGINSLLLNHMNKQKVKRRDEILAPYNIDSDDEKGTNARRAWVELGDRHPDFKYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX20</accession>
    <name>A0ABQ8VX20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="1">
        <location>
            <begin position="52"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="49933" checksum="DA440CEFBA0C70AF" modified="2025-10-08" version="1">MVKQSHAFTSVPLEGQTLPEFKETKGPSSNVISEIEKIEEGCKFTFPYKDGTRTVRLQRILFRSHGIIDRGTIVARVVCAYTHCVPNHCDWSGKKFVLKLSFPSVTRVSEKAFMDRCKEQAKGKHAGISNHFPDIYWSFDIPFDERCPQTNFKERSRDEYEMRVLQGSIQEELRPLLSLETALECAQVFYDIVQCHHWVYTYPQILHRDINYGNIMVRVQDGKKYGVLNDWDLASWRDKRDGISASQFRTGTRPYMAHEQHSPDWQGPHRYRHDMESLFYVILLLATLFSNPSEKDDNLAKTGYRYEPWLTQGDDFLYKDKALIILDLLWRPFPTHFFSAFHQWLKSLQRCLFVGFTAYKYFVKQQSDTPNQVLSFNDDTLDGHFSYDKFVLIMHRFSEEDLATHGTEWQGKLRGLQKDEDERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX42</accession>
    <name>A0ABQ8VX42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="31164" checksum="977D9F741B96CC84" modified="2025-10-08" version="1">MSITNNSTKPYKLSNYYATLALGYNELTLYQEAEAIATRALQLSPTSYRARYNRAISRWKMDDLRGAIAGVLSIDGLPEDVTTKPSRDSTFTLQLQWWNDPARIQEVRDLMEARNTRRKLEYNTRVENATEDAVEAGASAGPLQMKEKEDVLANTQAQTTNSKNKQFYMSTSEKKSIGSNTKEKERKKEKKHKARAAKRTAKRAQTGESATPDCKKTSTTRTYYPESKTIKSLKKLANCGFTNDEVVYLMEFGVNPWDEDVHSVFAYVDEYCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXI2</accession>
    <name>A0ABQ8VXI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydroxyneurosporene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_750287</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057722">
        <property type="entry name" value="AsqO/PenF-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056402">
        <property type="entry name" value="DA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25581">
        <property type="entry name" value="AsqO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24137">
        <property type="entry name" value="DA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046066182" description="Hydroxyneurosporene synthase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Diels-Alderase N-terminal" evidence="2">
        <location>
            <begin position="44"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="AsqO/PenF-like C-terminal" evidence="3">
        <location>
            <begin position="228"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="36603" checksum="F5AE3B747DAF2A57" modified="2025-10-08" version="1">MFFLWPLILPTLIHAATVSFPPTVGVGASDVLYTSSASSFDSLKISNVNSTTYEWYYFDAISDDGSYSVVATFFVAPNTAFPFTGSPTMTLEVLLSIQTPDSDVFYLNGAFATDAQVTTDGDGASGVWEGTGLSFNGSSDMSSYEVVIDSADVLGVTGTISMQSIAPSHYPCSAAQAGETMQLMPNIGWANAVPDSQATIQLEINGQNVSFTGSGYHDMNWGDIPFTDAVGTWHWGHGRLGPYSLVWFDGTSQDGTPYASGYVSMNGAIIGTQCSGVNVTASTSGFDIGIDLGDEGVLQAQFSTDHTLLSFDGVYYRWSGSLVGGISGGEQYTGSAMFDEFDFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY09</accession>
    <name>A0ABQ8VY09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydrodipicolinate synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_806307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF66">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="34928" checksum="64924D5A54818486" modified="2025-10-08" version="1">MSAVTQTQNTTSGPPPPGVYVPAVLFFNPGSEDIDEEAYKKHILRLAEGGVTGILVQGSNGEAQHLSHAERSRTIAFARKTLDEAGFQHVLIIAGTGAQSARETKELCVEAKESGAGWVLVLTPSTWAPAMGADSISRFHREVADASPLPYMIYNFPTVTAGLDLDSDLISSLATHPNIVGTKLSCGNVGKIQRLSSSFDYRSSFATFAGKSDVFLHTLLSGGAGTIAALVNLVPKIHAKVFKLFLEYQKTKDAKVLEEAFTLQSKLSAADWAVSKIGGVGGVKAIVAQEFGYGNGTVRGPLKEASLSALVQSEQGAKWWKASNEFNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY28</accession>
    <name>A0ABQ8VY28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_864167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="723"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="894" mass="99734" checksum="40FC43D313C65DE9" modified="2025-10-08" version="1">MSLDETQSSPEPSKPPDLQRTPRGNRILPTGRTHGRTPLPIDSIRPAPSRRTSSGIHASKPYERQHLQSIRKISDLTQMKHVQSNPTHKPELANHTAMTSNGRETQSDAEADISDMDLDMDVEPPANQIIELIELLSYKIQEAIQSCVLPSNFAEQGVGVELTGSEGSGVERILMSQLSAIHESIAADKEANEKRLERIEKALSNPSGCKTAQASSAPDWADVSYAAQATRPALKPPSKTKTTSSPAPISKRDVERETRFVAYFNGSVEPKDRKEPHKIVRRINNDIKELFPKCSNTKVATAKWNASGNLVLSVLPGQKAKALEEIFDLLYTAYTKTDAIPQDTRLDIEWNKIIVDGVPTGSTWSNQGGLGRRPHKSEELATEAKTYNPLLADKAFALAPRFLVPPADLVGKAESSIVFAIHDKETANDIISLGYIVMYGKRCKVRKYQDRSPTRPQCHKCHRFGHISERCTYQRRCGLCGEPHTEAEHTLQCTVCRDDASVKEADFTLDSLTEGSIPMCMHKLKCVNCEEKSLPSEHRADNRQCPERTRQMGSVRDNNRATGAGNAASSSFARKKKKTMKGLAKAPSQPASLTVSNSFAVIDPAVTDGIRFAQLNANKKKSPIVAMLNARIDEFDIIFIEEPNWSFIGKEGDNVVLGAVNHASAWTPISPIPAAPDSIHPRVYAYVKNGLHAEVTLRTDIVCDRDIMVLDVTPKGGRTTTYVHFYNDPSLGRQQILWRLRTLNLSLDHPTVFTGDANIHHIRWSRGAPRTSSITEEVVAWLDEHNFLLLNKKGIPTHFPHDTEKHPSVIDLTWANVHAAQTEATRDWAIDEDLALGSDHIGIRWVLNSQLDEIENPMGIRYNMKEVKPKDWIEAFDNEIERRKDKFQTLWRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY74</accession>
    <name>A0ABQ8VY74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_196687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="293" mass="33070" checksum="9A854EB2E8A74F8F" modified="2025-10-08" version="1">MSFSDNKSNISSMLMKSNRGDEFRAYASNPLFVAAQPQSRPLKQHGFKPVPDEVHREIALLLADLPTRPNTPSVDDQPRPQAFGFGNSGHNPFNMTLSSQSQHAQKHYSPGRPRWSMLDLSDEIRTSQQKLEPEEQGQPMSCDPSFVLPTYNREENNFMDVDVSPGQPQNQSQFQSMYTSNQDFTYSTSSQVHEESVESSIMMFNSLEPQTSFWKAIEMDVKAFPRPPLRAGLIFPTKRDIVANTPLGGSGNVYTSQGTRLNKPDIAKASASKNEHWRRLFQCTSKCRINVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYR3</accession>
    <name>A0ABQ8VYR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fcf2 pre-rRNA processing-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_807392</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="166"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="295" mass="33146" checksum="450CF0570AF47C52" modified="2025-10-08" version="1">MSLSVKGKEKAKVIDESSDSESENSSSSSSSEDEEESITQEFLDSLLEKARQNADLQDKEEQRTQEDQEDVLILDRIDHQPIPALDPGNLPPSYFNTSSFSKNQNGNESFPSGAAFSLSRDPLVESAESALARVAKSSLSASSSLLPPPEFHHGKVLTKRQRKELKNKTAGPDWFDLPAPPESDLPRLYREVEALRLRNQLDPKRFYRKEEGEGKGIKGLPKHFAIGKILTTDKPFGGASGENLTHAERKRTLVDELVDDAEMKRYAKRKFEDLQKVRGARGRNTKNARKRKPKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYS5</accession>
    <name>A0ABQ8VYS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="530"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="567"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="640" mass="71631" checksum="E5B174C51C550BBF" modified="2025-10-08" version="1">MVSLFSDMYGVRRLLDFDRTLPFAVSLFLKLRSYIGPLMYYLAALYASRMLSHTLLSSVLLLARLSFGYKQPFEYLEVLEGLGAAYADPASVLDGTLSTPLSVDVVGRVDATTTFVGQELNTEYLFGLFLQGSDENTTQLIGTPRSVTIQSSVVEPPVAAVSYIGEMAFPTVNMTVPLQIDMFIAFDNDMKIVSYDAILRRVGEFMAYTVPYLAPQIARELNATTTTVTELIELKTATDVCAVSTQYCTGDNQQYESHEVCMSFMTALPFGESWQGGMNTGWCRYIHKNMVKYRPEVHCSHIGPTGGDMCIDRDYAQVVDTNPFNQTLLAYNSSYNAADMKGIPTSNIAELVKVQTETVSMTTVAFFSVPAVLYMLFLYMMSKAAEFFLGRLSAPYREMCFDNQRNTVTYVLDTLVTGGVLILQIISSPILGDKYTFDNVNMLKSAALLISGLYIFELTYRPSMRWPLLIHHFCTIFAIVLLLSILAYTGHPALIAAGEIWLFQATTEQTVFVGLFMYRLRAPLRWTRDMLRFGAVQSFIFKIGFAAYLLAFWAQNLEQFHSTGDDVALSVILVTIILLLMCTQIYGAWAVWCLARKVNTSMQYIQRPDPPSRSSTASTFIEGVDKVDIRARLSIQQIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZB6</accession>
    <name>A0ABQ8VZB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription activator of gluconeogenesis ERT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_862275</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF7">
        <property type="entry name" value="FUNGAL TRANSCRIPTIONAL REGULATORY PROTEIN, N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="290" mass="32174" checksum="477CCA64B9085D25" modified="2025-10-08" version="1">MAAVVSDSTDIDTTTMDPSVHYPLLNTHPLTYSTMPMHMYPLTPSSQRTFHAKRRQVKNACTNCQKACKKCDDARPCLRCIKYGIPSECIDSQRKERKKGVKRGPYNKKRDCKGNGSVGNFDAPPHQQEVMPITNGEGPDNPSSSFHPALGLHYVGPATTYTGTTYINQYSLPPPLPPPLVKPPERREEPLPSLHPTSRHIHSQLYAVYPSQLPQGLSGQEYPSPPTSYYQGGPSRSAYHHVGQYPSYAVHVRADPHQQHLMTQPSYPYMAVAYGKPEGETYLEGQGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZV4</accession>
    <name>A0ABQ8VZV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit gamma</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_892420</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04198">
        <property type="entry name" value="eIF-2B_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04652">
        <property type="entry name" value="LbH_eIF2B_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="EIF2B subunit epsilon/gamma LbH" evidence="12">
        <location>
            <begin position="379"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="473"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="485"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4501871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="518" mass="57289" checksum="C1EA6E14A3940B19" modified="2025-10-08" version="1">MDLGVATSGPITREFSAVVIAGFGNELVPLTSNNGAEPCPKALVPLANKPMIDYVMSWIEQAGVKDVLLICPSIHRPMISHHVHSGLSTLRIDVQTYDESPEGNTGTCTLLRHFANRISEDFILLPCDFIPPPSLSLSTILNKHRTESVSDGSVATACWFAAQKPDKTSLVEDWGSIPPPVPIVWDDATGTLLQVDTADDSDRNSEELELRMSLLSQYPRTRLSSRYQDSHVYVCRRSVLDLLQEKKHFDSFREEFIPWLCKVQYQRTKREKYGHILNPITNIITQNVSLRHSTLRAQAKVYSKSVLHQSDDADASSPFDPESTTDSSSLRVGIVLHPATAGFATRVNNIHSLLDMNRRLLAETTYALPTDPQNRSLIDPKAQISSDTIIGAFTQVSERTTIKKSVIGKHCVLGKMARITGCVLLDHCVIEDGAKIDGCILGKNTKVGAKAELTRCVTQAGYEVGSGETFKNEKLDVSDWTAGPDESEEDDDDDEEETDDDDDEDGDKEEDDSEEEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W042</accession>
    <name>A0ABQ8W042_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_862478</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045753011" description="Transmembrane protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="33890" checksum="969AEFE2CC48FF13" modified="2025-10-08" version="1">MMLWCFQLSLYFLLGNALTITLPNIVVLETPTTINFVTGTTDPSQWILRNVYANGTTQIGGTLSGTGSTSFTFVVAGPHFLQALALTNGTAASAPFYTGNLFTPFNASAPSSTTSPIAAETQTVVSSSCPSSASAEGGSTETNNDTGTIVGSVIAGLGFLTALVFFLLWLNLRREYKRLTHVAPSVHQIQNAPSTIPLMASSATSFTQNAHYHSSSFPRSSLADSAPHMDNLASPLPPLSPQRRETKMVVVNQDVSTPTHTHNSSLDMSETSNPSSRRRGRDGLSRGALRREVSLLRRELEEIRQAHSYGVPPPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0E9</accession>
    <name>A0ABQ8W0E9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_862707</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17973">
        <property type="entry name" value="DEXHc_DHX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044756">
        <property type="entry name" value="DHX15_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="84"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="283"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="732"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="606"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="752"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4501044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="761" mass="85574" checksum="2FEC7217684099BD" modified="2025-10-08" version="1">MVDNPYLAHLPPSQRGAGPSYSSSSSEKEPLFGFLPRKVKGEQVRKAMEHHLNPFTKLPHSAQYRKILEARRALPVYSQMDEFLEIFSKNQIIVMVGETGSGKTTQIPQFVTYSDLPHTKGKLVACTQPRRVAAMSVAQRVADEMDVQLGKQVGYSIRFEDMTEAGTTFLKYMTDGMLLREAMNDKELSRYSTIILDEAHERTLATDILMGLLKNLVKRRKDLKIIVMSATLDAVKFQSYFSLHDSAAGEEPSPAPLFKVPGRTHPVEIFYTQEPEPDYVEAAIRTVLMIHRAEDPGDILLFLTGEEEIEDACRKIKLEADDLLNTDPSSVGPLMCVPLYSSLPPQQQQRIFDAAPKPSQEGYPPGRKVVVSTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEKDFISELEEQTHPEILRSNLANAVLELAKLGIKDLVRFDYLDAPAPETLMRALELLNYLAALDDEGELTALGGVMAEFPLDPQLAKMLIVSPEFKVSNEILTITAMLSIPNVWLRPPNQRAAADQAKAMLTVPEGDHLTMLNVFNNYSQNKHDRNWAWNNFLSARALAQAENVRAQLLRTMEKYDIDVISLEDEKKRNLGIRQALTCGFFMHVAHKEGEKGSYLTVKDNQVVALHPSCGLDSQPEWVLFNEFVLTKRPYIRTVTEVKPEWLLEYAPVYFDLASFPEGETKRALQRVANKRRGISNGGGEETRPRKKPKKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A0M8</accession>
    <name>A0A9W9A0M8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_520970</name>
        <name evidence="3" type="ORF">C8R41DRAFT_393101</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000028">
        <property type="protein sequence ID" value="KAJ4471776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A0M8"/>
    <dbReference type="OrthoDB" id="3182478at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="89" mass="10163" checksum="2666316A93A9555E" modified="2023-11-08" version="1">MIRRNPTLIPMNDNDVQDIRDIVNKGKVDPEGNEVLAAKMKKLADNPNFTNEDQKMLDSMRMWKEREDHERTVLPAETSGSGSAMRFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AU24</accession>
    <name>A0A9W9AU24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L31e-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_505346</name>
        <name evidence="5" type="ORF">C8R41DRAFT_866741</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000007">
        <property type="protein sequence ID" value="KAJ4489538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AU24"/>
    <dbReference type="OrthoDB" id="9739313at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020052">
        <property type="entry name" value="Ribosomal_eL31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01144">
        <property type="entry name" value="RIBOSOMAL_L31E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4489538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="125" mass="14136" checksum="0C83B9850E89570B" modified="2023-11-08" version="1">MAPTTKKTGGGKTRSALQDVVTREYTIHLHKRVHGRSFKKRAPWAVKSVTEFARKAMGTSDIRLDPKLNQAIWAQGIKTVPHRLRVKLERRRNDDDGAKEKLYVYASHVPVTSFKGLETVVVDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DZF0</accession>
    <name>A0A9W9DZF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_533829</name>
        <name evidence="8" type="ORF">C8R41DRAFT_911651</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000004">
        <property type="protein sequence ID" value="KAJ4493008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DZF0"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03751">
        <property type="entry name" value="proteasome_alpha_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000007">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4473480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4493008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="247" mass="27014" checksum="80FEB0CB819E9308" modified="2023-11-08" version="1">MTSIGTGYDLSASTYSPDGRIFQVEYANKAVENSGTAIGLRVKDGIVLAVEKLVHSKLLIPDANRRIQTLDRHLGLATAGLLADGRQLANRARDESANFRDSFRSPAPVKYIADRLGSYVQVYTLYSSVRPFGISTIIGGVDQDGPSLFVIEPSGVFFGYHGAAVGKGRQLAKTELEKLKLSELTMRQAVLEAARIIYLVHDDSKEKTFELEMSWIGDETNGLHVPVPKDLLAEAEQKAKAALEDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX05</accession>
    <name>A0ABQ8UX05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Subtilisin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_860799</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF15">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632045" evidence="10">
        <location>
            <begin position="25"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="11">
        <location>
            <begin position="252"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="528"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="569"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="588"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4463898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="610" mass="64246" checksum="93A635BAC22F57E3" modified="2025-10-08" version="1">MVPSRWRYTLQVILSLASIAVTYGASITPNPRAPNSRANPMSVHNRRSAVPKGYTPVSIADFNSMIQMRISLTMGNRTGLEDALNKASDPGSEAYGRWLSREDVQYYAAPSRDALYSVCTWLSSNNITPDSTTVSGDWIKFNVSVGTANSMLNATYNVYEHTASGKQSVRTLEYSVPSELGEHIRAIHPTTSFYHSAGPRVISLSGHHRSSSSAHAITPQADVDNKAASSSSSSSSAAIPTSTASFSKCNDTVTPACLQTLYGLPTGVIKTTNSTIGVSAFSGQDANKADLASFLKLFRPDLSSDTFATELLDNATNNQTLSDSGIEADLDIQYTVGLANGIPTTFVDVGDDTHDGDDGGFLDIVNDLLAETNPPLVLTTSYGVAGDESGLSRELTFAMCDAFMKLTARGVTILYATGDGGVASSPGEDCDDEPFLAAWPTCPYATLVGATANIPEKGADLSAGGFSNYFTPPSWQQPAVATYLAAIGDDLYKGRFNRSGRGFPDVSAQGDKIQIVQAGAVTPVAGTSASSPIFASVVALLNDELLGKGKAPMGFMNPWIYAHPEAFNDITDGSNPGCGTTGFPALKGWDPVTGVGSPNYQAMRKALGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY04</accession>
    <name>A0ABQ8UY04_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_804522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000147">
        <property type="protein sequence ID" value="KAJ4464072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0117">Actin capping</keyword>
    <keyword evidence="2 3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4464072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="297" mass="33400" checksum="9B96D047A58B967C" modified="2025-10-08" version="1">MESHERIQAACDFLLQSPPGEINDVLNDVRNIISDDELLQEGIVPALKRYNLAQFITVDVPETNHQSIISEAARLSTGSEDEESQERWLDPRSKKSFVFDHIALEASDPQPFEPNEDFETFRVALEKASLNYLLAHFHDGVSSAFSNQTTPNQFILQVVANKYNPTNFWSGRWRSEYIVDLNDHTIKGTILVNVHYYEQGNVQLSTTHSISIALPPAIVTASPESAGTKILALIETEEGKYQNSLNDTYHEMSEKTFKSLRRALPMTRSKLDWEKVLGYKLGAELSSSKGAFTSGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYX9</accession>
    <name>A0ABQ8UYX9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_117711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000139">
        <property type="protein sequence ID" value="KAJ4464566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045278477" evidence="1">
        <location>
            <begin position="23"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="147" mass="15957" checksum="51BC303CBF389984" modified="2025-10-08" version="1">MMCLHLASVLLAIVAMTHLSFGIPITSSGVDEPSQILSRVESDVKTVLISFNKPGPEGTKEEEGVTNTIQMLFDDAYSDTKGVIPPVKLAFKNYLATGRKTIALIPITFTGLDICRGECKAQADVFQKVSWIEDSTGKPLYEQGTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZH5</accession>
    <name>A0ABQ8UZH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosamine 6-phosphate N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_855978</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="2.3.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.4" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF11">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="20049" checksum="716587FFB83136AF" modified="2025-10-08" version="1">MSVKFTPDSSLDLLFPADLVAPELKAQLHPDVHIRPLASSDYRRGHLDVLSVLTVVTDPGEAAWVAQFNAMRSAASTYYAVVIIDRTTDRIVGAGSVFIERKFLRGLGGVGHIEDIAVDKNQQGKKLGLRIIQALTHISENIGCYKTILNCSDSNIPFYEKCGFQKKENEMAKYAPTSPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZS5</accession>
    <name>A0ABQ8UZS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_856185</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23285">
        <property type="entry name" value="beta-trefoil_MIR_PMT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF51">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
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            <begin position="246"/>
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            <begin position="601"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="14">
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    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="713"/>
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        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
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    <feature type="domain" description="MIR" evidence="15">
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
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    <sequence length="773" mass="87969" checksum="A2CA3F050B8D1A14" modified="2025-10-08" version="1">MAGTGKLRQRAPVSARANFEYDRIQEEEHTDDVYQNPNNRHPIEKILETDKASVVVVAVLTALAFALRFYKINHPDQVVFDEVHFGKFASYYILGEYYFDVHPPFAKLLFGLAGWFSGFDGHFQFENIGDSYTQNHVPYVGMRALPAILGSLTVPVVYAIMKQSGYSTVIAAFSAAIILFDNAHIAQSRLILLDATLIFFMSLTIYAYVRFQKLRYREFTSEWFGWLFATGIFMACTWGSKVNGVLTVATVGVAVLIDLWGILDYKKSPSMDYFWKHFAARAIGLIVVPFIIYLSFFWVHFALLPTSGTGDSFMSPAFQETLAGNEMLLSAQEIRYYDTVTIRHKDTKVYLHSHVERYPLKYDDGRISSQGQQVTGYGHADENNNWQIIPTKALPETGRGRIVRHNDMIQLLHVNTDTVLLTHDVASPLMPTNQEFTTWPRDDTSRFNETLFQLSLTDAHDGEAWKSKSGYFRLIHGQTRVSMWTHTKQLPEWAFRQQEINGNKNPSEKTATWFVEDIVADETGEDPKERTGHQPPKVPKKMNFFRKFGELQLLMLQHNAGLTASHPYASGPLNWPFLIAGISFWTENDPQKQIYLIGNLVGWWTCVVALSIYVGILGADLLARRRNNDPIPEPVRNRLWNSTGFFFVVWAVHYAPFFLMNRQLFIHHYLASHLASALIAGAVLQFILSETINYPISVEAPTMRRHKRQYVDIGLKGPIIFVLFCIAMFSMFVFLAPLTYGTPGLTGDQVNGKRLLSSWTLHFAAKKTAEVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V086</accession>
    <name>A0ABQ8V086_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
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    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000107">
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            <begin position="1"/>
            <end position="16"/>
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            <begin position="17"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467530.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="239" mass="26470" checksum="BEC830B7079BB6DE" modified="2025-10-08" version="1">MYLFFAAILVNVMVYAAPLPESSKFKTRLGRQVDNTGPYLPNIVNFAPNQKIVLFIGTHVFQYKNGQIFQEIVFFNRSNRYVVSGSSPHTQNYYNFIKLRPNREQDLSIEIDVLATMTVTATVNSMTPTDIHGEAGFWKLLLDILALQKIRSAKITSDLEYAEVVFGMLIKTMRSDRKTELLKFEELKECGVISNVPSNLRDGIGVPNSMLGAGIGGTGALAPPPVPLLSSSFDGTLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0D7</accession>
    <name>A0ABQ8V0D7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">C8R41DRAFT_925511</name>
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        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12875" checksum="1F4BC55730D56BD0" modified="2025-10-08" version="1">MKFSKWFRLGAYWLNVAFTLTTTTWFLKFNQFYLQLAPEVDNNGRIEVEREGLRMEDEDVKFKDVEDGGAEKILSEGSVFPNAGLIASPSDHSNSQYPTRPHPDPIPSLSQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0J1</accession>
    <name>A0ABQ8V0J1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">X-domain of DnaJ-containing-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_860923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
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        <lineage>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000153">
        <property type="protein sequence ID" value="KAJ4463776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924:SF1">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="123"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="615" mass="65754" checksum="354629EEEA5DF6D1" modified="2025-10-08" version="1">MYSSSPILPSRPVIPQIITTCSSCNSHVEFAIPMNPIPQQGTLLRIRCWKCEKVNEHMFYAAQISSHYPKDLFGNPDNTAAASSSSSSSSTTNRHSNAHFSTSGGARKGGRRIGTQERPLETVYYDTLGVPVTATTDEIKKAYRRLAIKHHPDKNPSDPLAADRFKSIAIAYQTLSDPTLRAKYNEFGARESAPEGGFVDPEEVFSAIFGGERFVGVIGHISLAKDMKAALQEAEEEAEEGKDGSDGAARIRDGKGERLVLSEEEKAKKEEKNRKKAAERAAARAERVDKLVANLERKLGIFTESATGINDVDVTRSWRTICELEAEELSHESYGPELLQAIGFVYVSKAKQFLAANQTFLGVGGWLHNVQGKYHVFSETVSTLRSALELKSVFDQIQAAEKAGNLSPEERQKLEEQAAEKGLQALFKGAKLEIDSVLREVCDRILLLEAEDPSSSSVGREKAVLRAAALQILGEAYVGVGTRKGGIGIQASSASSADHQYPHSRTSSPAPGTHSKPEPSSTPANGGSGLGGIGTGLGNIGRDIGTGLGGMFGFGGSPTTPSPSLSANASPSARRASRTFGGGQGRWGGQGGHGGSFDDSEYVRVDTKSSRARAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0M6</accession>
    <name>A0ABQ8V0M6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Shugoshin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_856966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="45696" checksum="99F208C973613B26" modified="2025-10-08" version="1">MMTSTVSSQDIADASSSRAAQRKARLMQIEYQQQLEDMEALKMSEEQRYTLMQSFSSVKVEFCDLDGLQWTGSALRKRTVSRPDSNSGILSQCKNLNQNSPRRARAQTLFCPSSPSLSSSNLSPSSSYFASLDTPLSSPKCRKPEALTPLNNVDFAPNFDEKTVRACVSPVKAALDSQKHTASSRNLDSRPPAKQRRRSRSPVKGAFISETKSSAKHESRSDVLPTVVVENTPVMPTPPAPAYTGGAPMERLESSSSRRSLTRTYTQAEITFGVSPTVATEVMRGRERSRGFRAPSKLALEDTMVFDESEEVIESDLVGLGPIRLSPPKADRERGQRLRGLAPQHPPSSARLFQSIVEEEDPLVTPTPERFSSVLEYPISPETPIQPRSCADFTLLKRKRQSSEAQNEVDREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0U2</accession>
    <name>A0ABQ8V0U2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_926018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="140" mass="15795" checksum="8D247489CC508554" modified="2025-10-08" version="1">MTVNFGPSSWTHIHTDSKNDVRVPCAITTGGKYNFKQSGHLILWDFKLILEFPPGATILLPSALVRHSNLPTAPGETRISVTQYTAGGVRRWLEYGGRTEEEFRAEVPQKFAEAWAKRNTGWKEGLHLFCTLDELKTCTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1L1</accession>
    <name>A0ABQ8V1L1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_930758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="299" mass="33546" checksum="FFAE945C7B138FFA" modified="2025-10-08" version="1">MTRNSAEEQAHAIVLLYNSGHVIAVIPQTFVYGIYTVLIPVSSYVMLYSRRGLATRARKILFGMTIFMFKLSTTHWIASIATLIRLIQVWFLAADPDARICPHGWSSRLACMGVMLGGWNEDFEDVSVYARSRYGRSRTEIRNNLDTAVDGRSRAGKNFVLLIETGALYSVSCLTVLMSSLIPLKGLDGTVADLYTPVSTQLAGIYPVVVLLLITQDYTLDRTVRAFASGGVEIQTGFHHSGQLDTMRFHRQSMADLVSSDMEENRSRDCRYYGILEWSFKTRTIERPATNSIFKNLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1L6</accession>
    <name>A0ABQ8V1L6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_855341</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10234"/>
            <dbReference type="Rhea" id="RHEA-COMP:10236"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="11">
        <location>
            <begin position="53"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4467584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="322" mass="36235" checksum="55FC3245F8E0225D" modified="2025-10-08" version="1">MPRATSDRFSRAHQSSAKASSSKSKDASSSSSARNPIFNTERFGQHILKNPQVAQTIVEKANLRPTDKVLEVGPGTGNLTVKILEQAKHVTAVEMDPRMAAELTKRVQGKPEQRKLDIIIGDFVKAELPYFDVCISNTPYQISSPLIFRLLSHRPLPRVCILMFQREFALRLVATAGSALWSRLSANVQLYAKVDYLMHVGKNNFRPAPMVESSVVRVAPRDPPPPVRFEEFDGLGRILFSRRNKTVHGNFMAKGVIPMLEKNWRTYCSETDQMVENEVDMKAKVEEVLEQTGNTENRAAKMDVDDLLKLLYAFHKVGIHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2F8</accession>
    <name>A0ABQ8V2F8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyl-CoA synthetase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_924761</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide synthase-like phosphopantetheine-binding" evidence="3">
        <location>
            <begin position="580"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4470725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1103" mass="122076" checksum="06D6A6D5CDB2DA5B" modified="2025-10-08" version="1">MAFTQTPSLESPITVPELLDFHYEHNPTRPIYVFAQDEQGITEISYLEFVRACHRLAHTIRPHRTGPERAVVAVVALVDTLVYETIIAGVIRAGLIPILISPRNTPAAVLNLLVKSGAHRLLTTYSTLKDLIDGIRLELQSNSSTFGFSLEEVPSLDKLYPHLGAETAADPFQPYPTCPIPLRPQEIAMYLHSSGSTGFPKVIPLSHAAMQVWGALPSATNLRDYKVPVRIGAMALPPFHAFAFYAQFACALYSAITVALYPPIITEANMLPIMPTSDNILLHLQRTKSNCTTVVPAMLQIWSRSDSDIDVLRSLEIVIFAGGPLPPAIGDYLVSKKVHICSVYGGTEFGCVTTLKLTEDRNDWQWHRFSEEVEINWLPQGDGTFECQFLAVDSHALAVENMSNPRGYATSDLFVPHPTKEGLWKIVGRVDDVVVLSTGEKCVPAPMENTLLMNPLIQGVVMFGRQRDQPGVLIEPSPGNEIEVDDPEQVSNYRNKIWQVWPVIEEGNRLVPAYSRIYKETILISSPEKPLPRAAKGTILRKAAYQLYENAINRIYEIIDTNANSSPVDPPTSWESPQVQQWLTHQLQGLCGVVLSPTVDFFEHGIDSLSATILRLRIVTVLRTCATLSPGSRSIADIFAPNTVYNHPSIQSLADYIVDLVHFEGSAATPIVVNDNHAHIRLIDAMIERYSKGLELGISLNPEFTPVNNNNDVSSPSRVVVLLTGSTGNLGTQILSRLLKESSVHLVYALNRRSTRGSVMERQKKRFLDKGLDSSMLHTDKMVFLEVENTLPKLGLSDEVYNELKNNVTLVIHNAWRLDFNLSLSSFETNIHGMRNLIDLARSSRHATSLRFLFTSTIATAQSWDTVEKGPYPEELIMDTKYAVGMGYGEAKYVSERILAKSGLNATSFRIGQISGSSPSGAWAMSDWFPMIVKSSLKLNMLPNANGVVSWIPMDAVADAIVDVGLSKPSSPPFAVNLVHPNPVPWSRMILDVRMAVIRSKQLKADALPVVHFHTWLEALQAVVDTPGIENEAPAVKIIDFLRDMAHADKRIGLHQSEHMEAVGLTPLVTTNIQRISPKIATLSPLGNYDAELWVHYWAVSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2K3</accession>
    <name>A0ABQ8V2K3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_780483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="174"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="620"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="735" mass="80209" checksum="B0E6B0BA429B37EF" modified="2025-10-08" version="1">MSKEKERARLEIIMEKECIFLKGTGVDVEPARLSGHVALYLSESTSIKEITLQFRGKARLPVPSHESISLNSAPLTFIVCNHEWSFLEGEKRHSHTLKAGRHFFPFQLQLGGSLPSTVSTTVFGGAFVAYKLRAHVSRPGLSHNLQSQTPVTIIRSFAPEALEYQQTLEIENTWPEKLMYSIMIPHKAWACGDTVTALVKFSPLLKGVGVLNINTSIHETVKVYTRTGHQEHNRAVASMKHEIVGGKAVEVHEHEHRQRTAQTPCGSPSPGTPSLSSSYRSTGSAGGYFAYSPNGNQTSQPGPSVLPASLSASPSSQLLRDPVEGLEMSQDDVVTYLLLPIPLNITPTHVLDPIYVTHRIRWSILILNPDGHTSELRCSLPLHVLDPRLLNEARMNTAATRRLLIGGPEVPAEETEDDMELPSYHAHVRDRIANMYLPESATMRITNPWVRDGVNSLGGNSDVVSPWPRSRSGYSSPLDAHALSHLPHAPGSGDSTPLDWVNSELLLLHPDSDPHTQTISHSSQTSSEVSPDHSNPSSNPVTRPNSRPASSYPSRRSSRASSPERGGHVNPQSLHVAGPNETYIHTGKDSRNIQGVFKATMKPFTSLTHPTWLGSRSHSHNSLSSLTSSSSLTSNLSHDRPGQSMALGNRTLQLSDYNNTQEAMQRVPDYQIASRGFIGGVPPLTSLRDLPSYEDSQLGTRTRSDSDLASRFAGVSLSPMATVAGRTALPTPPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2T0</accession>
    <name>A0ABQ8V2T0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046615641" evidence="1">
        <location>
            <begin position="19"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="23780" checksum="5E2048FF97A6F696" modified="2025-10-08" version="1">MHISILAIPFVLTSLAAAAPFHQPRICFPCSMEDHAAELQSEVDLSSIKHGDLHDVAVSGVDGGFYLTDSLLAAAQFACRNLEAKAYVLEYKWTGANLPVKEYQKGAEFTAFLDYDKHAEAPSRNAALDQIMADNDMITRQYAVIKQQAATNNLKYTSTYEVPCTAVPVGKDLFAEYYTASQKSSPHFDQLVKLLMQCEPGIGPWQEAVNAEKNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2U7</accession>
    <name>A0ABQ8V2U7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_599474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF42">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SIK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4471212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="386" mass="44395" checksum="714FD339F01FE0D9" modified="2025-10-08" version="1">MGNYEYHDRIIGSLLPTHSSSDLYALDESELWWIGHFEFLKNHGYMMRPRYRPGWKPSYKPGILEPLFSEDGQSQDHPYVMDALRISDSYMVAMKRVKVSTGEDQVATFFSNEQHNTNPRNHCIRVLEVLSVPGDDNEKILVMPWLRQVMDPRFRTIGEAVQFFQEIIEGLQYMHENNVAHRDCASNNMGMDANLMFTRQYHPINPKKRHNWSGRALHHSRTRCTPKYYLIDFGQSRAYNPSESRPSEYALKSGGYTPPEGDAGIPCDPLATDVYILGTMIRTSFLDGDPNVSKPGVYGFEFLRPLVNDMIADDPSSRPTMAEVASRFSDLIAKLRWWKLRSRAVQKDEVLAKPFRAVYHVFWTVSMMLLLKPAIPSPKNAPDVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2U8</accession>
    <name>A0ABQ8V2U8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039751">
        <property type="entry name" value="HERPUD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943:SF27">
        <property type="entry name" value="HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943">
        <property type="entry name" value="HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="650" mass="70096" checksum="DC6071E4295556FE" modified="2025-10-08" version="1">MSDEHQPAVPTIPILVELPAYGYSFTVHLPSETTSTSAASSNIVLSIKHAISRTCPGNPQVDGQRIIWRGRVLGDAEKVGELWPVVEGYGGQGLKRIVHLSVHPSAWTGKPPVISAAREVRESKEVGSEKGKGKEKEIVADKDDVVNKLRAAAAVTFESSTTTSKSAPTVTTAPSPPPALPAYLISTHRKALSALTDLEGFTPEAFTSSDNEKETAIRFVNAHGYSWPAILDEGYPSTDADSEKGVKYVKDVIDGRPYLRLLNPTETPTAAQKHALKVLSFTFELLKLPTQPSRYTSSPSISNPTAQPNQPGVPVPETTPAVQVPAHLNAVLQQMGLPPITENLPPGVVNVIQQPQQQVPQAQGGVQFDLNQFFNANNLNNNNDNNNNNNHQIQQINIRPILLPLLMLSLRMFLLLYFVAPARKPFLMLLVLAWVGWEIWGWIAALGVRVEVEIERGGGRMEGGGAGERPPGGGGVPQPAPPPAQQNAAAQAPPAVPAANNPPAPAPAPAAPPTLLDNLASFGIAQDQAALESTLPLETDSQEPGIARKVLLFLVLFLISVHPAVWNRRRALLRAREGQVRVEMGVLAEGVGEQESGAADNASALETTRRAQRRAEMYVKYMSRPAWVRRYMQRVMSAQAGEGAWVDEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V333</accession>
    <name>A0ABQ8V333_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_778021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800:SF5">
        <property type="entry name" value="FER-1-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="35"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="477" mass="53289" checksum="E141EAFF6C4E716B" modified="2025-10-08" version="1">MPGGSTNPISLTGFVEKVSETVHKAKTHMHENAHDLAQVTKQKEEDKLNGPCVDVIITFISASGIPKLDVVGASDPYFVAKLDDRVSMVSTVKTKSLAPEWNELWRVKNVPTTSELRVEILDKDTDTPHDDYIGKFKTSIEAGEKEIDIQGPLFRKDRGTFKLKTETAPSTDPAEPKYLFDGPIRYSRHFSPLVGKLTDLDDARLYSTWKMYLIDVPIYFKDVYQHWNVKYKAAQSIFGSGPTSLAIRAGIHAGHKMLYARSTSNGFGVIQSVDDVMRLFEGGSLDPKGILGKSPFAHRIKPAVYTYIISAQDDSLRFSETGAAFFVDFASKHALHADCAEQVRYSGEFHLRPRAKDHSSWCGWQDFNDSMPDDSVDWEVVIDNNSGTYAPDKAMLPTLRDLIDCNFPGLDVVALDREDDELKKSVDACQEYALKYRGVKSEHLQPHQQEGHRSLLKPLGAVVGKVAHLQRGNKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V385</accession>
    <name>A0ABQ8V385_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_851840</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4470482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="464" mass="52524" checksum="84B9134A9016691C" modified="2025-10-08" version="1">MIVLGTHKAAADLLDRRANIYSDRPDLIVLNLLTGGMHWGFARLDDLWKRQRRGAHEALSAQTVKDYFEYQETESVIMLHQMLTDPENFADHFSRASTSLALSIIYGWPPLLDSSHPLIPLVDQFNRELLVAAAPGSFWVEFKYFKWMQHLPRWMCAWRRNAEASFIRDSAMFEKLSYDVQKQINAGDEATSVAGKLLQDTGTKGFFEAAWNLASIYSAGAETTAGQLAWFMQAMILYSEAQRLAQEEIDRVVGPYRLPTFDDYERLPYIRATVKEILRWRGVSPIGLPHRLIQNDYYEGYLLPKDTICFVNNWSLHHDKTIYGDDAEHFNPGRFLDDNGNLKSSIVDTRDEGHASYGFGKRICVGRHVANNSLFIHIACLLWAFNITSEVGGHSDLPDSLQCKEGLIVRPSTFRCNITARQADVAEIVAQAKADKGIRDCDTVFSKGMNDHDAMTNTPSVSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3C9</accession>
    <name>A0ABQ8V3C9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4469833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="138" mass="15292" checksum="CBEDC05620650296" modified="2025-10-08" version="1">MDKSLTLKDLFSYVPSFCMIWYQADSHVGLKGYWWNWLSWGNISFLSSSRKATIRATARSTAAKSQAIFPQATTAQLDILEVPTLTSDHTAALKDAEASIHSASPVYGNYRIGSLFLDFQAAFGTRVLTEKDSGYITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4A3</accession>
    <name>A0ABQ8V4A3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="37889" checksum="7D451BED0C812BC3" modified="2025-10-08" version="1">MPNNRVNFFMYGSSPSRSSSATTGIPSRSSQPGLGVSSSTFHPHTQVSPVGTTSPLSSGEISSRANKENPPSSMPGHFPEPEIVFVSLSTTCSEEHSNDAKELLEQLNSLKIKSANLQEVVADIYHMGAQILLHDEGDEKFDDGGVSIQMFIPFTTDIVRQTVFSVESYIKTLENTGMRQTKSSNLKKFLRKPVLRRLVPNKLTKSNDNAHESFTITLVELHTQMRVIHFIAMPYDKPSTHSQKIDNILAISANMGSVLTIVFDGVPVLGMLKPAVCALSGICTAVQTFRSNKNLAVEILYTVRDDIRWVIRKIQKDYTSRMVYTTEGPWELGKDVNEYFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4P2</accession>
    <name>A0ABQ8V4P2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_850119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4472387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="8353" checksum="99EA3DD6C92C377E" modified="2025-10-08" version="1">MHVAERELWLAISQLLWSFDFHSLPGEPISLEEYEGLSGRTPLPFRLKLQPRHEFVELALKGDQEVTYWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V576</accession>
    <name>A0ABQ8V576_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_847799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="37894" checksum="FA34BFDEE4438DF0" modified="2025-10-08" version="1" fragment="single">THYDNDIISKPLLQWSHNTNSWCTDITTCAIEIDKKRRPILLKKPEVTTPLNLERYIERHDNLKSDKKVLKRTWEEGLQEKQSIEEGVMKRICSPKPKTRQRALTAPTHTQSLSFITKHFEPILYSPTPLPTPSPPPYDRYQTEAHAADMRQYLKETLLYVKSPQPVTLESPQPVMLKSPQLVTPKFPQSATPKPDTRGEDGTMRAQLKEEHRVCVSGVVASGRPWPHGMIVKDMIDSFTLVDSHYWKSRYPHNQQDRINEVFQGVSVDKRQFHKQRRAWQGMTRDEWAYAQSGGHEQEWVQWRKTSKGWKEENERNHRRIAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V592</accession>
    <name>A0ABQ8V592_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MADS-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_847380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="36103" checksum="92DFF86412A06ACB" modified="2025-10-08" version="1">MPDNEELIRRIQTSNLHIQHSVMANGYIYACFVLSQKPRESVHVRKLMDLTAGAKTLRSDIHMQAIQMQQLQIQYATSMPCHIMARMRFLEINIAEKRQDLDDIMRVLSRLNNNNRDHDGNDNAIHTGTLWGLPSLDSSQLGQSSSFGNVIQSPITTSFAGSSLTLLPTADGHTPKWTSPYWEAVASKSLQNEDEPQMVHNTKGIERDNPLPLNSTIIFQQNSSSDAGVNDASIDSPIQDEDEDEFNMGIPDLIPSSLNSSPFYGFGIIDDDTTALLDVKQQEYNNLWLGVPSKRTGGGNSANSPHWDGHSATLPSSKDWAMYSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5V4</accession>
    <name>A0ABQ8V5V4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Pentafunctional AROM polypeptide</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="21">3-dehydroquinate synthase</fullName>
                <shortName evidence="21">DHQS</shortName>
                <ecNumber evidence="21">4.2.3.4</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
                <ecNumber evidence="21">2.5.1.19</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="21">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
                <shortName evidence="21">EPSP synthase</shortName>
                <shortName evidence="21">EPSPS</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">Shikimate kinase</fullName>
                <shortName evidence="21">SK</shortName>
                <ecNumber evidence="21">2.7.1.71</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">3-dehydroquinate dehydratase</fullName>
                <shortName evidence="21">3-dehydroquinase</shortName>
                <ecNumber evidence="21">4.2.1.10</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">Shikimate dehydrogenase</fullName>
                <ecNumber evidence="21">1.1.1.25</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="29" type="ORF">C8R41DRAFT_924886</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="29" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="29">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21 22">The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:21257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20 21 22">
            <text>shikimate + ATP = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>shikimate + NADP(+) = 3-dehydroshikimate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="21 22">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="21 22">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="21 22">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="21 22">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the 2nd section; belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the 2nd section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the 3rd section; belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the 4th section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the C-terminal section; belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="22">In the N-terminal section; belongs to the dehydroquinate synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21">In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="29">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="21"/>
    <dbReference type="EC" id="2.5.1.19" evidence="21"/>
    <dbReference type="EC" id="2.7.1.71" evidence="21"/>
    <dbReference type="EC" id="4.2.1.10" evidence="21"/>
    <dbReference type="EC" id="1.1.1.25" evidence="21"/>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08195">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="entry name" value="Enolpyruvate transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03143">
        <property type="entry name" value="Pentafunct_AroM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056179">
        <property type="entry name" value="DHQS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008289">
        <property type="entry name" value="Pentafunct_AroM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010110">
        <property type="entry name" value="Shikimate_DH_AroM-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01093">
        <property type="entry name" value="aroD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01809">
        <property type="entry name" value="Shik-DH-AROM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090:SF5">
        <property type="entry name" value="PENTAFUNCTIONAL AROM POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24621">
        <property type="entry name" value="DHQS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000514">
        <property type="entry name" value="Pentafunct_AroM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 21 22" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16 21 22" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="13 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 21 22" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 21 22" id="KW-0418">Kinase</keyword>
    <keyword evidence="17 21 22" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 21 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18 21" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="14 21" id="KW-0521">NADP</keyword>
    <keyword evidence="10 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 21 22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 21 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 21 22" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="3-dehydroquinate synthase N-terminal" evidence="25">
        <location>
            <begin position="81"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="3-dehydroquinate synthase C-terminal" evidence="28">
        <location>
            <begin position="195"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Enolpyruvate transferase" evidence="23">
        <location>
            <begin position="417"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="26">
        <location>
            <begin position="1320"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="domain" description="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase" evidence="24">
        <location>
            <begin position="1436"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="domain" description="SDH C-terminal" evidence="27">
        <location>
            <begin position="1565"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-dehydroquinate synthase" evidence="21">
        <location>
            <begin position="1"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate dehydrogenase" evidence="21">
        <location>
            <begin position="1315"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate synthase activity" evidence="21">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate synthase activity" evidence="21">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="active site" description="For EPSP synthase activity" evidence="21">
        <location>
            <position position="834"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate dehydratase activity" evidence="21">
        <location>
            <position position="1204"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity" evidence="21">
        <location>
            <position position="1232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="46"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="143"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="272"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="880"/>
            <end position="887"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRNR" id="PIRNR000514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF24621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="KAJ4470278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1602" mass="173695" checksum="1E93C593EBEE8E39" modified="2025-10-08" version="1">MTATTDVQKISILGKESIHCGFHLVPYIVNTVLTELPASTYILITDSNIAKFYLPAFEKEFKSTLSGLLNGTHARPRFLSYIIPPGETSKSREGKAAVEDFLLLNKCTRDTVILALGGGVVGDLVGFVAATFMRGVRFCQIPTSLLAMVDSSVGGKTAIDTPHGKNLIGAFWQPEFIFIDAALLETLPSREFSNGMAEVVKTAAIWDDSEFNSLESRSAEIFAAIQTPSTNYAGRSEKTRSDAQKLLLSVIIGSISVKAHIVTIDPTEKGLRNLVNFGHSIGHAIEAILTPTILHGECVSIGMILEAELSRQMGILSQVSVGRLTRCLKAYNLPVSLADPRIANLPSAKLITTERLLDIMKVDKKNQGNDKKIVLLSRIGATHEQKASVVPDGLISKTLSESVTVVPGIPSFNPVKMTTPGSKSISNRALVLAALGTGICRLKNLLHSDDTQVMMAALSELKGAKFEWEDGGETLVVHGGNGFLSVPPKGKEIYLGNAGTAARFLTTVCTLVQKPPTGESETTVITGNARMKQRPIGPLVAALRANGSEISYLESDGCLPLSIRPNGLSGGIIQLAASVSSQYVSSVLLCAPYANEPVTLELIGGQVISQPYIDMTVAMMKTFGIEVIRRVEKDTGKLLDIYDIPKGSYQNPSNYSIESDASSATYPLAIAAITGTSCTIQNIGSSSLQGDAKFAREVLERMGCEVNQTATETTVQGPPIGQLKAVEEIDMEVMTDAFLTATVLAAVANGKTRIIGIANQRVKECNRIRAMIDELVKFGVSTNELDDGLEVFGKPVEELRKAVSVHCYDDHRVAMAFSVLASLVPGTILEEKRCVEKTWPNWWDDLQNKIGLEVKGVELSTPSVSLSSAPLSPKSVILIGMRGSGKTFIGDLAASALRWTFIDADNYFETVHQVGVRQFVHENGWPAFREAETKLLKDLLTEKGHDHVLSLGGGIVETAAARDLLKGWVSSGGLVVHVSRNIGEIIEYLGTEGSRPAYGEPVSEVFERRATWFAECSNHRFINHVEAFADGKIVVDPTDTKRGVREEVVRFFHHISGVSANLAQNLMPGHRSYFLSLTYPDIMLALPKLEELSAGVDALEVRVDLLRSKEDIEPLGKHIPSETYVADQIAALRRVSSLPIIFTVRTVSEGGAFPDHAQKEAFSLLKLALSLGVEYLDVEMQLPEQTIKQLVARKGSTQFIASWHDWSGRLKWNSPEAQAMYNIAAQNGDIVKMVFTASTMQDNFDCQAFALKMNGRPDAKPFIAINMGAVGQLSRIFNTTFSPVSHPLQPSRAAPGQISFAQVQKALHLIGELPAKKFYLFGNPIDHSLSPTLHNNAFETLGLPHTYELLETAEVGEDIKNTIASPAFGGASVTIPHKLNIIPLLDQLTPAAKVMGAVNTIIPTNDGATRILVGDNTDWLGIRGSIAARIAVGQIHAALVIGAGGTSRAAIYALNDLGAKVIYVWNRTRSRAEELQASNLDMNIQVIDELGQWPTGATAPNVIVSTIPASETSFEDDTDRLFYPASLYSYRDGPAIVLDLAYKPVETPLLKLAKMTASNWDTAQGVEVLLQQGYAQFEKWTGRKCPQGIVSRKVWEVYYNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V794</accession>
    <name>A0ABQ8V794_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="102" mass="11412" checksum="238B339E31B303C6" modified="2025-10-08" version="1">MPAHLRESLEIAIQACLSDTSAQFNHREPSSSVETASFSSLHFTNQTRYLTHGYEAPKDIHPLYLINAEGGRMNHSQLLCHPSEDIQKLSGPYADLKQSLEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7W1</accession>
    <name>A0ABQ8V7W1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ubiquitin-activating enzyme E1-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_852709</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF5">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="10">
        <location>
            <begin position="19"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-activating enzyme SCCH" evidence="11">
        <location>
            <begin position="311"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="632"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="8">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4469842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="715" mass="77197" checksum="C4DA2B4E2EDCBF5E" modified="2025-10-08" version="1">MPTTTTTTVAGRTKHAKAILGDELHKKLGETKVLVVGAGGIGCELIKTLVLSGFIDITLLDLDTIDLSNLNRQFLFRTTHIKKPKSLIAASVASTFNPLVDITPIQDNIMDSEKYHVDWFRGFDIVLNALDNLEARKYVGRMCVAGGVKMVESGTAGYLGQVQPIVGGVTECFECMEKPKGGKTYPVCTIRSTPSLPIHCVVWSKSYLMGQLFGVDEDAGAELDEAEKQGENAEEIANLRKEAESFAQVRAAIRSGGPAARMIFDKIFNTDIKRLLSMSDMWNHRASPVPLDFDRIMQGENENGNGSKQKQTVALKDQKKLTTKENLELFVSSVSALSARLSSTETVIEFDKDDDDTLNFVTAASNLRSLAYGIPQKTKWEVKEMAGNIIPAIATTNAIIAGLIVLQGVNLIASSFSPPTSTPTSPSPSPLSSLRNIHIQLKPSVPLSAITTSRPNPACGICRDIYTVVRCDPLRATLRDVVQGVLGLSPPPISEFTIFASSPSAPSATRILADPDWEDNLDRTLGSVNVRCGMFVNVVHEEGVWETISVGIGGLPPDAGCYGGNANRNRNAEGEGEGEGIPWLMLPDPLPRLVVRKEEKEKSGGTNTPLPPPPVERASLKRGLGEDDDIVVLDSNDNHSADAHPPAAKRRKTSSNPPPSTPPERQHPARAGFSSPSKKRKLEEDGLVLMESAEELLDDISEDINGGEGDVIVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Y2</accession>
    <name>A0ABQ8V7Y2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mis12-Mtw1 protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_501754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="643" mass="70587" checksum="AAE6E4242A2173E2" modified="2025-10-08" version="1">MNVMTGRPPTASQRSQAKLVASGSKRKLLNGEEIPGGLVIVRPPSSQGTRLSTRPPSQPPPDRPPSSNGHPQKDLDASIPPPAKKFRADSQPSTTSKAGPSSLKPPVGPSSSKHISRTPEIEADVRAMEDEADELRRKARARALDPALRQEYHPPPRPPDQKPTSNGHSRKSRIIDTTQALPSAHSESPMITKNKRLREGAMMAIRSASQEPESGESSQRGREATVNNSGGGRRSHRRNSSVNGRGKRISESFEATGKLSHPHSSISESSFFKHIDTEISDTERLLLLLTWCTSRSAQSYASTSNPASTTLPLLSEQEVVILSNVQQDLLRQLADRKIDIGPNPQSQSSGAIQHTRANNQNVSNQKYEKNFSQEIRQMEQEQELWKKANYHYEELFKKEQGKIEKRKSDISHRQSLSEKAKGKRKASDDLHEDWSWLPSEHLPESQHAGCSLAKAVLGLSTDPSGSIQRTNTGIRIGREDVEAALKQEISDLPFHMDTLLTHVNAARLTTNVAESVLDERFSLLSRALAARSGDISDFAQAGTASTTTQILNHYVPPAPAAPLRPLSNAQSIFRALARVDSARPRGQIGDAARRAAREVHRMEESGIARSSERRLTEVPPTPRKIPTTPRRGNTPGRGNTPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9J2</accession>
    <name>A0ABQ8V9J2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_798213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4482642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="33065" checksum="ED3AAE25D72EA24C" modified="2025-10-08" version="1">MSSPSNSPYSPIRRSEHRSGSTSPTHRRPRSNSHRSAVPPGFLSHKPKQTPISEMSVWELQNKFSRNAKILASSNATSSSYVQRITAEQAAIQEQLVEVHGMEVINTGLKNTRITGDDDSESIIGIDDVEMKPEPAHPMKNAIDAKKRAIARFGATAGPSHIGMLGMDEAIEIEQRVHVHDLQRKQRIEEKRMHHGYPMQNEVMSREEREARIWAFMNYKPSESDLEDADDDDEDDDPAGWFEDDQDDGRKGQNIVEPDEEDPESLHNIIHVMDPNQMHYNTFYEPRDDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9P9</accession>
    <name>A0ABQ8V9P9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_548006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="183" mass="20191" checksum="9CB934989B920A2A" modified="2025-10-08" version="1">MRLVVSFPILLATCILLVTYPIMVTASPLIIGRAGAPKGFSSSSRDYSKSERFILTGRTSSAASFLYAISSKNEPATVGLVFGHQGVQGVSLLTKRNGKVALEKLNVDYPTLRIWDIKIDISAEAQNEVKAKTEASNIDGVEWVLEALDIMKKRYDKGLTKSQKSNLLVDMQRWAKDVEKKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAD5</accession>
    <name>A0ABQ8VAD5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_463386</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF4">
        <property type="entry name" value="URACIL PHOSPHORIBOSYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="8"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4482624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="22868" checksum="A6A551163E025F7B" modified="2025-10-08" version="1">MVGVHKISHPIVNAELSKLRLSSTSSKEFREGINHIALILGLEASKDLEEVTFDGQTPIAAFKGTNIKPRVGLTPILRAGLGMTDALLTLFPYAPVYHLGIFREKVTLQPVEYYSKLPAQPPVDIVYLLDPLIATGGTAVAALTMIVDWGIPVDKIKLLCVLASQEGLKNVQSGFPGLEIWVAGIDETLTKEGLISPGLGDTGDRLFNTLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAG2</accession>
    <name>A0ABQ8VAG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047284261" evidence="1">
        <location>
            <begin position="25"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="180" mass="20240" checksum="2F67E9D3CE61C825" modified="2025-10-08" version="1">MLSFYPLHSLPLLSLLVMFLGATAAPYNATVDIARRKSSVDGVGMTFKRVVNAESNSPELLRKAKNVYVSETWTLVIGRDNAYRAIPDPNQPGHYKGHKFRERYAGKPITLVNFGTVEKQTEAYKALADLPAVTNLLYLDEIFNYLLQMGAINEIPALWTSRYTEMLDLRGDALGHQLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAY3</accession>
    <name>A0ABQ8VAY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HRDC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_444490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="4">
        <location>
            <begin position="23"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="134" mass="15051" checksum="473FD8B9D2E6B3F5" modified="2025-10-08" version="1">MTTRLRHRPTGEEEDAAALKLGPEFNNAGCLLISEVKYLLENRDKDAPDTAVYNKTLEYVKTFTKFSTTDSASAVRETLRREPALTQFETAQIANLCPADAEEAKSVVPSLVKLDDDRLQALLDEIQTMRKFQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBD1</accession>
    <name>A0ABQ8VBD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase PFA4</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Protein S-acyltransferase</fullName>
            <shortName evidence="11">PAT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Protein fatty acyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PFA4</name>
        <name evidence="15" type="ORF">C8R41DRAFT_838780</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11 12">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03199">
        <property type="entry name" value="DHHC_PAT_PFA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033682">
        <property type="entry name" value="PFA4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="14">
        <location>
            <begin position="90"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="276"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="368"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" description="S-palmitoyl cysteine intermediate" evidence="11">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4485131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="49985" checksum="BD3FAC464C411227" modified="2025-10-08" version="1">MSSLLGRLIVNFVVLLISFIAYSSQIFVIWPWYGRVISVELLVLLVPFNLLVAMLFWNYFLCVNVDPGRVPEDWKPDTHSDGFEVKKLTGKPRYCRMCKSYKPPRTHHCRQCNHCVLRMDHHCPWINNCVGHYNYGHFVRFLFYVDMACSYHLAMMVRRVYHNLNISYWDSIAGIEFVFILLNFVACIPVLLSVGAFSIYHFNGISNNTTTIEGWEKDKVATMIRRGKIRDVKFPYHLGRRRNIESVLGPNPLFWCWPTKPPGNGLKYELSGGEELEEAEQQVWPPDDPVQPYFEEPEGEFKLSESPWTFENEGVNPDLQPYNTKLREDSVTRRRKSRKAAGYSSLPPYHPDYQGSEGGQSSESESSDDGKYNDSGRVRRGSEGYEFKPTDREDILRQYLAQVSGTPGRYKRYIPQIESESDEDDIPLRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBD3</accession>
    <name>A0ABQ8VBD3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_846857</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="11">
        <location>
            <begin position="25"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4475851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="417" mass="45472" checksum="1E61EAD8BF184FCE" modified="2025-10-08" version="1">MSTTTTLSNNSTFTNSNAKEPLKNVIVTGGAGYIGSHIIYTLLKTHKYKVISIDNYHNSFPAALTRVSELALTELKASLPTDTSPSPQDLDSVAIDVYKCDLLDSSLVRSIFSKYSSQNGGTGIWGVIHLSAYKAVGESSVIPLTYYANNVSATISLLQIMQDFGCHRLIYSSSATVYGVVDEIPIKETTQRQIEGKEGSVYGRTKVMCELIVEDLCESSVLTGSTTPFQAISLRYFNPAGAHPSGYIGEHPRGRPENLLPLLAHMAVGTVKDPVLKVFGKDYPTPDGTCVRDYLHILDLAAGHVIALQALEEGSELNNRVFASTTETGKGSKGRFKAYNLGKGHGMSVMQIVGAMREATEFDFKTEVVGRRRGDVPELIADPALARAELGFDAPRDLETMCRDLWNWQEKNPTGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCF2</accession>
    <name>A0ABQ8VCF2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small ribosomal subunit protein uS10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_836708</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="5">
        <location>
            <begin position="185"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="354"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="430"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4487426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="441" mass="47973" checksum="9A67DD3697EC6E9A" modified="2025-10-08" version="1">MYKASNHSYKSFRRLISASPHFKGLTRCAGFPLNHIRASSIHGSAAVLYPRKASRNLETTEDGFDSASIQELIDRDNLGLDSFDTEDDFEPALFLQKDSVTEPPELAQSEDEFFGVAHSRFEQELPPISPLPSGLDPRQLPVKIGSLSDLGPNPSEEAYASALVHGRSIHLPYIHPRTHSIPAGNITFYSHHPRLLALFTHVASHAASSLAIPISKVIMLPTERSLWTVIRAPFAYKKSQENFQRKTHKRMIKAWDAAPEVIDRWVKYLEKHAMGGVGIRVTKWERLSLGIGKTRLARVKEAFKAPLPNGLSSADAKLLEIQQEGDSDANRKQAIQALGEKILKEELQTFEGSQKPPVASLGALGASGDTSATERVHVSADKLQVKGTRKIPAKGINKTSSTSAPKTKVSLSSNGNSSAKAETVTLAKAGQSTSASAPGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCP5</accession>
    <name>A0ABQ8VCP5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">deoxyhypusine synthase</fullName>
            <ecNumber evidence="6">2.5.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_896736</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine</text>
            <dbReference type="Rhea" id="RHEA:33299"/>
            <dbReference type="Rhea" id="RHEA-COMP:10143"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57484"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="EC" id="2.5.1.46"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00321">
        <property type="entry name" value="dhys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703:SF0">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4482740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="357" mass="39779" checksum="165B9728331877D7" modified="2025-10-08" version="1">MAVPSGASAAVLLPSEPISNDHISVKGPNLEKSLSLFDFLQSYTRIGFQATSFGRAIDIVDRMRKWRLSDEPLAEDEDEKYRSPEIRSETKCNIFLGYTSNLISSGLREVILFLVKHKHVAAVVTTAGGIEEDFIKCLGNTYLADFNLDGADLRRRGMNRIGNLIIPNDNYCKFEDWLTPILDAMLAEQKETGEVWTPRRFIHRLGKEINNEESVYYWAYKNDIPVFCPALTDGSIGDMIYFHSFKNPGLVLDIVQDIRELNEKSRKSRKAGMIVLGGGVCKHQIANAMLIRNGADYSVFINTGQEFDGSDSGARPDEAVSWGKIRAGAEAVKVFADATLVFPMLVAATFAKDYQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCX4</accession>
    <name>A0ABQ8VCX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_837274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="28"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4486949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="328" mass="36347" checksum="42EB21169223A546" modified="2025-10-08" version="1">MAITITSKDVHDIDIAGLTIAIVVTFTRLGIRIKNRKLGWDDFWATFSIIGAALLMTGVLIILDPKPSMTQLTRVAGYYITSEGFYTIVWTSRLSILCTIIRIAPPGTMRKILLVIGSLFGVMWIFLAMQEIFICEREPDWKAAVPTQCHLGKAVAITQLITDIIADLCLLIAPLRLFWNSMLPSGHRMRLNIVFSTCLLTTIVSLVHAYWIFANLGLNEIFTGIFETTISMIVASLNVLVGFLYHTMTKGSSLPSERTGTGGQGIELHGRSVATGPISVDITTTTYTDAEAGAFKESNKRHQDIYNLNDGLYEEGDKKSEIVQFRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDK9</accession>
    <name>A0ABQ8VDK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="737" mass="82784" checksum="91999971FB9F2DCB" modified="2025-10-08" version="1">MESDTTAHRKYKFPPFPSAPEHLTVVPFEDFKENGLKIQNDDYDGPEVDTLNIPTVVIGKRHAGDVCKTRSERTMSVVAPQDEAQSFELPQQTTWLHRWEDLSTRRSCERYNRNQNRADRIHQATRVFNTGRPWPKTDKHVREQWDQFQLYIGILNIMPIWRPIQDSIELEDDADVEDDFDDDEDLFSPDPKKITRRVEMGTERGERSSYQKKNPRPRPPYENYDKPPVEVKSQQEIDQLLQESRDRKADRLDEFLNNPKERVQVYLSSYMRKQGLHYVDRNLTLIPLLIRFYINFLIKEEVFSIESEPELIASLHEALIIINLAEFELPLTSQITKSLPWNDVFSGGCEELFDVRSKEQEISALEWAQRNQGLFLDVESGENGVSSTAAATVASTPPAEEAKGLELEVDIDIVTPTMEQNSDDVLETPTQVTQQKNDAPSPVTTSPSSPWGSDEGTAMDNFEPPANTFGSWNTDLHKADPSAAGWGGMELDDITENLWVGDDVDTWEIPPPPTLFPILGPTALPLTHTSGVVEWSMRRIRSVVNPGDDNDSSATNVIASKFLSDGPSANAVESDFSSRLSKVVMEPWLDWETSGEEGDTASPQIKGTSRGSVKVYEKGQGVMYEYDSDVRSNAFAAAPSPNGTSLPAHDPLKHTITLLVAPETAKLLRVGMGLGATWVQIARQTDLRNEQEVRETEIEGSGGESISSPDGSGDSDIHGRFWYLSNLLIVLPSFHIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDM3</accession>
    <name>A0ABQ8VDM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_981679</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF812">
        <property type="entry name" value="2OG-FE(II) OXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="178"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="371" mass="41789" checksum="35B69D1C2E175737" modified="2025-10-08" version="1">MTDRNFSSIPLLDYSLALSSSTKSQFIIDLRHALINVGFLYLSNTDSMVDRHLIDTLKDYIPKLFALPQEEKDKIRMANSLHFLGYSRLGAELTKGKTDNREQFDIATEHISRWKSGDPDYWNVWGPSQYPDEALIPGFQQTMKTYLSQVAALGTHFITLIAEALGLPPEGLSRFYDTPDRMQHRGKVVQYPVPSERSQSDQGVGPHYDAGFLTILLQASPHPGLQVQNLSGDWIDAPPIPGTFVINFGRALEFATKGIARATSHRVLSPPVGSLSPRYSVPLFHNIALDVRVRDSKYELEFPPEILKLRDERGNLAHTDSINYSEFESQPSGMVQLMGRVKSHPDVAQRHYPALFKQFFPEGLPKQGFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEE6</accession>
    <name>A0ABQ8VEE6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_417774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="359" mass="41756" checksum="890E493FC9BC7763" modified="2025-10-08" version="1">MNQLLSSRPPLATDSMSDDELYTLIMNMDWNRTGVGYMPDLDVMGPPPVYHIKPYKLVAKHIAFDPWTEVYAMHHVHQHTTIPIPQVHRVIPDQRDGGRGFWLIMDFIDGECLLEAWPKLSWWRRFQVVCTLRSYIQQLHRAPLPSPDIPGPSDGTGRSFTCLGNHFDDGAGPFSTYAAMAAWHDHQNHRFQVLLHHQGVKKIWQYSKFDQSLPLVFCHFDLHMRNIMLDKNNRVWLIDWAFAGAYPAWFEYIPLGSTVKTANPMFSLPRSFAWFIGFIVGGCCAPWYYDNYIGDFYLRIESYRKRLIDSDYFVKQGIDPKLWQPADVARPSLPHVMVQRCFDIVYDTFLVVRGLFVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VER7</accession>
    <name>A0ABQ8VER7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_959988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127066" evidence="1">
        <location>
            <begin position="27"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="214" mass="24214" checksum="D5BC61BAD1326035" modified="2025-10-08" version="1">MLLASVLRRCLFTFSGIIYFTRTASAVPIGAGSDNTTTHGNGHPSQVLLLKYDYEPVINGPDAADPNILGEALQIIVDSLGITETHPPELKFALAPGRGYAGDSDDLYCTGYMITFHMRRGRGFDPSICGAYHAFIQYAKNFNEKFPQERAKILSGQLYRERYYARDTYETVLTFRNGKVQSGHWKEGKKTLDMVDHKEWWMRTGFRSSRDGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF30</accession>
    <name>A0ABQ8VF30_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein SirB1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein SirB1 N-terminal" evidence="1">
        <location>
            <begin position="220"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4485188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="532" mass="60136" checksum="E56E784DD693B91D" modified="2025-10-08" version="1">MKSDIIARAGRISGIPPSRDLDSIFVKTIVQCFLTNTLFREAAAIPALWQQHYQVRYLHANEASEGQRKAETNGNWKLMHAARKMIDPEVLKHLNSIVMKRVGRYDHANALTKFLFDAWDVLEIEIGMVDLGKYLEIRGWGDKFAVGYSRGFGAAFDQTTPYLLYKPSPPYLASLVNIRMRYTVSLLSSLNYRCKAHLSRLNIPLSQVGPRHDLKELCMHICDFMTTERYRTVDPPNFYDLHNLFPHFYLTSHKRSIPLSLVHIFVLIAQSFGIAAFPFRIPLHVLVHITVPDPEVDDFFVDVFGVPTIINLRDDIPAIRERQGIHGNSLMHYLSPSDTTTMLLGNDRFILSSFNLQPFTLFLVLTGTSQSVPHLMSQADPLDCATFITEVLIPSLSNIREVQNELRQASQQSLEEEASTTQEIKLRTPTNTTLGYVAEDNIKPLLSASDELLSQKCQGVRILPKLFTGVLTKTTTRSSNVRDAPVQYRRARFVLSLELATAYNTMGDAWLGGGESVYTWLPAKELSVGINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF78</accession>
    <name>A0ABQ8VF78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_732449</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="80" mass="9117" checksum="37CA260B78E9F6A7" modified="2025-10-08" version="1" fragment="single">YNHRIFKKFNDYPTAKMYYEELVDSKILDMLQPAPEKDEVFIVIRGVRPGVYVKRCVACSIGLAWRGGEVMVTVGCKSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFM3</accession>
    <name>A0ABQ8VFM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_765202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="782" mass="89680" checksum="D0A2D4048B54A907" modified="2025-10-08" version="1">MLLNPLPTNVPPLGFSAARHGTQSHTPASESTPRSSTSVNESALRHLLHTNYKISRKTTLSVVYQYPADSILEYPETGATSEEVVGHLFELGMDNWISPGRDFAYSRGEPRGNGKECVTNPLLVHSTTGEMVPCIVRHSTCQGVKICPFFDGDKEDMIHSSATREQLRNLMQHSREQQMEFSSPARDVFERTSAYLTAIRRVGCTSDANLGQDASESALAGFERIALRRGYPEMPNRCTGGLIFQWSFDGTPYIKCEHHSRFHNRDHFFDNTIGNGRFNVEYLEAVLTDDHEEVGRIELEAQLDGYGPRTSCHTIMNNTSQRLTCTWDHRDQENGSLKQPNLISMECRCTFREYEPLEDYRSSCPYILITSRGPHSHPIPLPQKTPRKVKLELESLFEKMEVELADLTPRKFLRHPIVQCYLSSRFPMLRNPMLSDLHISLSNRRLKHLKAQQDSSLEPEAHYIRAVIEIPFTELQFDEDDLTEDQPNEIALQPLKIAICMTLEGSRRFIKTQYLQSDIGFKRIVGFYEFEIASIDKYSNTSITFCRVYLNRQTADAHRLVLREINKILIADTGRGLKWRHLHGYDVDDYDGLILNWVVDQHRGQAKGIGLYLQDLAGSLAPKMDFHQPLRRIQDLSPYDHLRRFLTLCTTHFYRNIRKCAVSEEVRSIMRGLICVQHDDWDGALEQIRRSGGKAAQNWLSDKETSRFVFPAICWEKSYIPFDVWNARLRESNVVEVVHANVNMEGTQCTLVGGVYKGKHYDLLKQRSLIVSGQLFPKYMSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFZ9</accession>
    <name>A0ABQ8VFZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_919649</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="120" mass="13136" checksum="A41227573BEC0F7C" modified="2025-10-08" version="1">MPTSTLSGVDSGVDRNPPINTLYVENLPLSPPLGCTPGIIEDCLRELFQTRPGYENLLFRQKRTGSMCYVEFKDVSSATKAIDELDGNALNGLAKHGGIHLSYSKNPLSFQTHTNANRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG84</accession>
    <name>A0ABQ8VG84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_831780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="269" mass="30461" checksum="3C08464B517980DD" modified="2025-10-08" version="1">MRDLHVDDKFHKRQTDRWNAVDLPWGHRAGLHALPFRCLRYLQIRWSVFSWIPPCVLLEGEESSAVHADPTQWPGYQLAMLFKANANTLDHVSIDEYPGFRSENYSSTQTSDALLHLLAKDVPKLKLLFLGGPMQRVDNIPIPEISFDLPQPTDPDALLVRDRPLYPSGKEVPYVHPNFASTINHDSDCAHLSLDCFAIRGFDLESTLLIEDTLLNSGALSATKYLALFAMPVNFNYMFFLSRLCQSLTHLTLDLDNTSVFAALPYTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGD3</accession>
    <name>A0ABQ8VGD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 92 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_325734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF25">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047166539" evidence="1">
        <location>
            <begin position="21"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="3">
        <location>
            <begin position="32"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="2">
        <location>
            <begin position="293"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="801" mass="87484" checksum="D783DF8806E8F8CE" modified="2025-10-08" version="1">MRTVSLLITVLSASLASVKTQAPILITDPASFVLPFIGTTNGGHVFPGATLPHGMVKVGMDTDSPGNQAGYDANSTFNATGFSQLHDTGTGGAISLSNFKLWAFPNCTSFEDCPTSLESRKALRKVLPDGSPDDFASPGYFSTNLSTGIRVELTSTRRTAIHRYTFPEGTAQPRMVVDITNDGPRTSTNPVMTLDPTTARVIGGAQFAASFGPGRYTAFTCVDFAGEGFELGQPTEFGTWLGNFPVQGQTDIDQLYFGFIDELGALFTFPPAPDGTPTVILARAGVSFISSEQACANAEEEIPDFDFNRVQTENRATWNELLGRVQVDTTNVSTETIQLFYSAIYRTHISPADYTGENPRWNSTEPYYDSYYCNWDTYRTLYSFMALHDPVTFSRIVRGMIDIQKHEGWLPECRGATVMQFIQGGSNGDPILGEFFVKFSDQAAALNVSADDLYTALLADAELQPPNWNLQGRQADAWKQFNYIPQDMFDAGGANTKQVSRTLEHAFGDFAISQVAKILGKTDDAAKYSQRANNSFNVWNPDVSVPGTPSVAGMMQPRFKNGTFNFTDPRHCSIHDPEMATCFLNAANRDGFYESSPIYSQYVPHDTAQLLRLQGGKDSFVSRLDFIFNQSYFDVTDEPSMQIPFMYHYANLPGKSTQKSRQVIAESFNTSVSGLPGNDDSGAMASYTAFYLAGLYPLPATRQILLSSPFFPSISFFNPLYNSTTTIKANGFEGNPADGTGGKVFVQNVTVNGELYKSNCFLDWDVFVNGSVVELALTDDPNVTCGSGDEALPPSLSTGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGM8</accession>
    <name>A0ABQ8VGM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_835617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="302" mass="32984" checksum="6D85812247D179F7" modified="2025-10-08" version="1" fragment="single">MDVGMQMSGTIVAVSQLPPKYRKRAQIQERQGDHLESFSMEPLLKSDESELKHSQSTSDALSKTSARKARKSPQGSSSMSPVEPRRSSRIKDNLERRTQSVQSFRSRAGCKRKADEISIETGSQTTGILASESSISSNIPSSSLGLYPVKAKRVDLGYRCSSINSNPNETLCASCGAVVCLFGIVGQKLQVEDSSNIKERHKRVEVKTDNKNQSRILQRATQGPRIRVNSGANTGVNSAVVPPPPLDPKCASIVSDTLIMRSTGSLLWDAYKEEHGEPPYGEIPLLWGERKAGGQSSKSRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGQ0</accession>
    <name>A0ABQ8VGQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="51159" checksum="8159EF5E7C6017DF" modified="2025-10-08" version="1">MPGPELKGSYQFFFRCSYAPFFLSQVCRRWRTVALSTPALWTRFIVVLHRTGQAELIECILERSRLLPLHVIVSSRDNGRRDNYLRAMNTLISNISRLESFVLEIPEGADDLAPTLPPIPPAGVPNMRSIEFYNVKSSEPSRTSAWISELLYRSPNLQSLHLQLAEEIKLKGTVGVRLQNFKASHGIQLQDLFTLLVNCAGLRTCEVQFRAPIHLGVVPRTRVLLKYLHTLILRDARRDDLEAVFRWLTLPSLKKLTLSGLRGAEWPDELFSNFLSRSRFSLKSLSLTALFFTEAHLLSYLHHSSIHDSLEELAICHWRPSSASFLDHLSFKLPSPDATHNPPPFLPKLSSIFITVDAITQVVALRRFVASRWYDTAAYEVPLPIASLKDIHVCLTVPYAPNVNMSIDDIKLVFSRIARSRGTSLRLETITMAPPSSNQYAGIERLTGHLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHF9</accession>
    <name>A0ABQ8VHF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="538" mass="59790" checksum="DD94F09529BCA1D6" modified="2025-10-08" version="1">MSFHFSPTTGGLGIITTATTPRLASQPISQRVENHPPGVTGIAPRPSRELSTTPLRPWTPSIGAPIERQGGNTGSFTAHSTFSQVQDLPAPGRGQIFSGMEYIYIIGRPYELLTAPDEHNERAQSLSNTLSFFTNTGSRRSSMGRFTWLYQDVVNILLIPGSIPDDVDGLNQPDIHSPLPALNRSNTPVFANCMRANPRPEHETTALMTWVDEIRPQFTLEPRQVRELKGMVMVAPSVETEPLKLHLLTHAAICRLENKSNANSDTASVKEVVDSAMKQLSKHIEIPSTSKEIIRTLGRDECANPARSSYGDVGKAVWARCKAEADVHDFSVFLSKTTHETAFKKVAEATGKKMLQQFRDDILATIVVDESGRKEPLNLEKATHILCKKYVKGGGGGTLHQFRFAMIRRFMRESECEEEGPVLKRRKIGNGGRQMQDEAFWGRFDKYLKEKMDEFGMNMKDDKWKEYLTETVQADWQRFGEPNNSLLPALPLVFNSNGFTAVCVPLQDIHDTSNSGGSGIAQTAGETPIGQQSDYDHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI05</accession>
    <name>A0ABQ8VI05_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_918986</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047364105" description="Glycosyltransferase 61 catalytic domain-containing protein" evidence="9">
        <location>
            <begin position="37"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="10">
        <location>
            <begin position="445"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4495271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="634" mass="70607" checksum="926764811FF2FF05" modified="2025-10-08" version="1">MGSHGHGATPAPTPRELVLVCIFLALLFFMSQHSAGSDNSFLADYSPPLPPLKLKSPPLNPFPSPYKTESFIQNDGLVRETTIIKHVPGWTIIDSLYMHNGTYYVVTSNPPIDPPQTKYDPAQSPFLKLPPPKAILSKGHDIYGARGGMGNDPLRAPDALYLRYVSTAEFQNLFGIDLSVNEVEEGHVHTVPGLTFILNDSPQFITHYYHFCAELWFGVWRTYASLGGGHKLPPPTRVLFPNLDSAHWRDYANMNQLFMRSVLPSTQMLFSHDWYDWVSLSVIDKPTSESKTNGGTMKGKPILFPRVLLADRSAAMPAFNYQRFQRTAAVPFGLLIPQGEEGGDWWSPVRDSVRVFAGLDDDSANGSPTNHESQSQLESQRTDVQSALIHKLPNPPHDRLTVQDLIKPTVEERFSKWMAPLPSPPFVGSEDYETLKENFLVPLKHHANPGGKTDALSLLATSLTRQRTTRPVVTYLSRQDWNRRKLKTEDHESLVAELRKLEVELGIEVIVVSAENLSRWEQIRLVGRSTILIGVHGNGLTAELWMNLGFRSTVIEIFYPGGWAHDYEYTARAMGAGGGLKHYGIWNDEVLTSPGFPPPSYPPGFQGNEIPVDGKTVANLVRDRITAAGQLDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI74</accession>
    <name>A0ABQ8VI74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_730497</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF177">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER MCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046851742" evidence="4">
        <location>
            <begin position="22"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="1"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="41939" checksum="72808F2822317D85" modified="2025-10-08" version="1" fragment="single">AYLTIFGAFLALFCTFGQMNAFGTFQAWYTTHQLNTLDASTISWIGSLQLWVFFFSGGPIGYIFDKCGPRMLMMVGTICYVLSIMMTSISTQYYQYILSQGVLFGLGVGLLFYPSLSSVSTHFATYRATATGLAVAGSGLGGVVFPIMLQNLFERVGFGWATRISGLLCGVLCGIAVLTVTTSTSTHKAPAQLAGLQCLKEPRYMLLAAGGSLVALGACCFVPYFYVVDYAQSLGISSHMAFVVLALMNAGGVFGRVVPAILSDSIGRFNLLAPTSFLAGLLILISWMFARTLSTLIVFSILYGFFSGAFISVITPCVAQISDIREIGMRIGLMYSIISFSALIGGPVAGLILGFNHGSYNGMVIFAGTTMVAGSLLILGVKFLINPMLLARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI90</accession>
    <name>A0ABQ8VI90_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_338124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="93"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="26577" checksum="9A2ADADF352B14A7" modified="2025-10-08" version="1">MPALMKHVRFSSINALYSPVPSTPYVFTASTTSTSTSSSHSSRPEDLKSSRRRRHVSKLTTHLRSKSLDIPAPITRIHYLLAFSPYQMPPIPYHLSTHPSITKSFISADVLSEPATDPPVSSLIITCPHLQWEFPVTTSSRKASCVSVIDVLYALYRGLRIAVHPVEYKALPSSEAVANVNEAYYSRCNSIPEAQARQGEHSKGIKRVDFLIGRTRFLGLSKKSRRRDDGLVWELNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIM0</accession>
    <name>A0ABQ8VIM0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_296373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115:SF1">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="23"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="149" mass="17383" checksum="F98C1B174DE0E1BE" modified="2025-10-08" version="1">MHHYVLLPKIAYFDIYAHDQDLQLSPAFALPFTEPVSRVIELAYDRDFSHIPVLDKDRRPLGYVEVSKLKQLWESGQANPSDKVSQYMIKFKRTSSEPYTLITPLTSLNELEQFLQTNIFALVTDFQRKFVIGVATMHDLEQFVNRRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJG8</accession>
    <name>A0ABQ8VJG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_831013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="13215" checksum="33D7896D2D5499BE" modified="2025-10-08" version="1">MLVFQPPVQNTLRLLSDRAFFDQINVTTWFPDVDVLYLGGTRSNWMCAWGEIKTKKRYLQARSRKDSHVREIQFFDMDGLNHLAHWDQTQEFLQVVAEGIRLHYLGRWSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJQ2</accession>
    <name>A0ABQ8VJQ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphosulfolactate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_895607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphosulfolactate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003830">
        <property type="entry name" value="ComA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036112">
        <property type="entry name" value="ComA_synth_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48413:SF1">
        <property type="entry name" value="PROTEIN HEAT-STRESS-ASSOCIATED 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02679">
        <property type="entry name" value="ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102110">
        <property type="entry name" value="(2r)-phospho-3-sulfolactate synthase ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="32212" checksum="FE7300FC89C82EC4" modified="2025-10-08" version="1">MSASNANTTTSSYNFLSSNYLPPKPRDHGLTEIRGPYYYPVTQTYLDELLSDWGEFVDGVKFAGGAFSLMPEERLRGLIETAHKHDIYVSTGGFIEKVLSSSNGNREVIQKYLETCKNTGFDVLEISSGFLSIPTDDWADLVEMTAKAGLKPKPEVGIQWGAGGDASIAELESAGTRDPKWLIDRAKTFLEAGAYMIMIESEGITENVRNWRTDVISAVTSALPKEKIMFEAADPEVFAYHIQNQGATANLFVDHSQIVQLACLRKGIWGTGSTFGKIVTVGKGESAGSHRIPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK66</accession>
    <name>A0ABQ8VK66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="426" mass="46452" checksum="E7C1E7FFCDD27D08" modified="2025-10-08" version="1">MASTSSQTRSSAATTLLPTSLMEAQVLLAGLQSKSTLPLFFESPVFQRLQQGDYVPPLLSPQHTPDYDGSSAFPAFSYPRALVPFCFPLETSRPLSVASGLDLFCSAQMAIRTLQLLTDDSPPTESGEVYNVFEDAAPFLIYIRDFWMGRGNCPLFAEQVLLSAELLSLNLPVFLRDNLTQQWGIPPEHRPLVEGVHNFERFPAIPIPFCLRFREGSAMMRTVPSEDLDVFASLRGKGSPGTSKAVSPPKVSDIVSPPPATKAQALTLPPFMNATPRASSSAKVPVGKKEPKSKTTVKVVEDSKSSKPTPSAMAYKRVRLPPRSRKIAPITAKGKSRRVVVSDDDSASNEVESEDEEGDEEEDEDEEEDSAPPSKRLKTTSSISALLPRRSVKRVTVPKRVSKAAVKPVPERSPESTFQPVLLADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKM5</accession>
    <name>A0ABQ8VKM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_240766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="40851" checksum="89F61F8239A10254" modified="2025-10-08" version="1">MTMETMGINLHWSSHGFGPDGDPDYKKTILIFLSTKLSSYTRMSDTSSSSSSTFPPEDYNLKAYFISLHHHQHDTIKPTTLAPEQENIFTADKGTYDFEQNLSSSVLNNIRAMLDEEDSSSLNFLVEDKTLNPRADPFVPGLMNGAGSCASARLVAIDAINRFDQRYDRPLPPLLRPSPGLESSPWLASTRHPPNWRHSLDLAAHMTPMSESSIDEYGRDLVHGQIWSRCGLVDLIQHVCWKGSEPSFDTHPLSVALLAFSVYNHFKAIGDRKNASTFTDILQQCVKGYFEAFWDVENKGSALRFTPDSSFAPEYIQETVLHCLWILICQLTAPEHLQRYRFGASLRQKSRRCYTTATIECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL76</accession>
    <name>A0ABQ8VL76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF427-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_831340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="entry name" value="Domain of unknown function (DUF427)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310:SF5">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="94" mass="10635" checksum="E3DC6C849A333384" modified="2025-10-08" version="1">MKAILDGIVLADSNDTKVIEGNHYFPPDSVKKEYFVESDTSSVCPWKGTCSYYDATISGKTVSDVAWYYPSTISDRAKPIENYVAFYKNKVQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLQ0</accession>
    <name>A0ABQ8VLQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_249754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046300740" evidence="1">
        <location>
            <begin position="31"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="210" mass="23251" checksum="79E192BE6AA85537" modified="2025-10-08" version="1">MPTFGSLRFPSLHLLLLCVLSSVVLIITAASPSDPEHKVVLEIELIRQPHVGSLPIAAQFDKNDNIIPPPAVDEHGKPVAHPIDRNGAVVAPPKADEDWDLCIGGYCLKLLFDVSPRHLKKVILTGWNDEWAEDYIGIGTVTFKNKKQMYSVINSFRMEIAKDAESNLLFLNAVIHWFSNNAQAKGIIAEIKMDVWEAYFKAMHSVGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLR5</accession>
    <name>A0ABQ8VLR5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_980080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="32541" checksum="42BF02FF42BF0EAB" modified="2025-10-08" version="1">MSKLTIQNSIRKVVLHCDASQDTVRTTISIELKRVKLPNDLIRPRKRPTGAFAGYFLEEAPIRPPSALPPPGDLTLETNLSTFLGSGRTGIVYSLENAVLSDSTHFLPELVFKFARLHRCADLYREAWFYEEMECLQGVAIPRCYGLFEAEIPPGWMLKLIKLIILRSTRNKLCILVEERLGGHLSIGSPVSPELREDLNTLFEEIGHLGVLSENDIRYANILQAPACPPGLPSLVSPFTFRTHGWRMIDFEMAAKTQQTARALAIGHQEYLEYILDALEAGYVCDVGGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLT3</accession>
    <name>A0ABQ8VLT3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_731009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="52" mass="6038" checksum="91EF53C8B5009339" modified="2025-10-08" version="1" fragment="single">YHTFVRQMKGTALPKKRARSNQALLNWLEKKALVEWVKYLGLTGHPVNKCTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLX9</accession>
    <name>A0ABQ8VLX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_826117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="178"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="332" mass="36871" checksum="7F78A9F03EC83E21" modified="2025-10-08" version="1">MSAITTQAVAETLGAVQLGVLFSTFLFGILFMQWVAYFTSKFNDGWTIRGLVFWVMALDIAHVAISWEYLWMYTVANFGDPTTLYASHWQYDSGPIFIVLTAAPTQFFLVNRTRKMLGRQHPILANCIFALACTLGFVQVFMGLYMSGSLLALDASGTATTAGYVKFVPVAVAWESVAIATDMTVMITLVATLMYRRTGFKQTDWMVYNLVLVAIECALPVTLFTIGHITGVVASPTTAIHQLFAWSQARLYSNTLFLNLNERSKLRRGQDATSHGSSNVKEVNFLSAMERGTGRNASRPQVHIDVTREEHYVMQSMSNKGDDSDFKPTPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLZ9</accession>
    <name>A0ABQ8VLZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_320554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="93" mass="10530" checksum="CC8B70139B44F36A" modified="2025-10-08" version="1">MAITESTHTLFLRIFLYITTYILLYYLDITTVPINCATASYYSIFLALQNITNKCTVVLLFSAMNSNVSANAKKTLQSVDLMTYILIITNPYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMB3</accession>
    <name>A0ABQ8VMB3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxidase</fullName>
            <ecNumber evidence="12">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_208758</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="12">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00692">
        <property type="entry name" value="ligninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024589">
        <property type="entry name" value="Ligninase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11895">
        <property type="entry name" value="Peroxidase_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 12 15" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044970660" description="Peroxidase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="14">
        <location>
            <begin position="63"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="340"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4497528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="378" mass="39850" checksum="E1424CD7457DD3C2" modified="2025-10-08" version="1">MAFSTSTLLQFIALALSTTVSAAPSKNIRCSDGTVVPDSICCDFIPLAQDLTETLFENQCGETAHEVLRLSFHDAIAISQSLGPSAGGGADGSMLIFPDVEPNFAANLGISDSVNDLAPFLASGKFPTITAGDMIQFGATVAVGLCPGAPQLEFRAGRPNATAPAVDGLIPEPQNTVDEILARFQDAANLNAEDIVSLLVSHTVARADHVDPTLDAAPFDSTPFTFDSQFFLETLLTGVGFPGTTNNTGEVSSPLPLTVGENVGELRLQSDFELARDPRTACFWQSMINQEALMAARFKAAMAKMAVIGHNANDLVDCSAVVPKPVPALNKPATFPATKTKADVQQACPEPFPNLTTDRAPRETEIPHCPDNEATCTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMK7</accession>
    <name>A0ABQ8VMK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_879375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="3">
        <location>
            <begin position="115"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="400" mass="44164" checksum="F087FF80EEE703A8" modified="2025-10-08" version="1" fragment="single">MSRDGQKSTASTPLSTVDITPVSNSNSRPGLGPTVQSPSNPHTTKRNDQNASSSISENNLNRRVKDGSAPLPSLLGISQAHPHTQYSGGRSFNYEEKYAPDPLGEELNENARVFKVYLDETESFDDDMLRGFRETIDSLLVFAALFSAVVTSFIIATIASLQPDYSQISAVLLMEQVQLLRAAGNSTAINAIPQPSIDLQNASVDANTLWINGLFLTSLSLALVTALLSVLVKQWLQAYTSILAGNAKQRAMIRQFRYHGLVKWKVPEIIGVLPIILHMSLALFLIGLTLYISVLHSSLCWILVTITSLAFTFYFGSIFIPQFKLECPYRIPLLFAPIKHGIHAFTALMWILGWVVAKTLGNIDDFKHRYGHTPLSSLSQTANLRDYELLHLRHGAQGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP89</accession>
    <name>A0ABQ8VP89_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_916838</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="11">
        <location>
            <begin position="26"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="348" mass="36861" checksum="BD8FD701D9B1CC37" modified="2025-10-08" version="1">MLPRRSFVIFRSFLTRNYASGSSPHALVFLEHRQGDIDSGSLSALTAASQLGGKVAGLVVGSSEFVPTVVDKVKKLKGLTSLLHSTSDLYAEQLPETLSPLLEKLLSDSEYTHVVSTPSSLAKSLLPRVAAKLDVPSVSEITSLEHDSSSNSTTFTRPIYAGNAISTVRLPSSVPIKFFTVRATNFDPAPFEESQEIEVKAIDPVDVPNCPTKHISTQLAKSDRPDLSVAGRVVSGGRPLKNAETFAATLDPLADVLGAALGASRAAVDAGYVDNSLQVGQTGKVVAPELYMAIGISGAIQHLAGMKDSKMIVAVNKDPDAPIFQVADVGLVADLYEAVPQIIEKLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPQ2</accession>
    <name>A0ABQ8VPQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="25910" checksum="D1DED84D68E5E0D4" modified="2025-10-08" version="1">MTSPLAGLEAFTGNQTLISTPRNNSTLGQDVGITDWARTGSSLFGGGHNNFNNNFLSMNNKLIGAVPGLLSVAPGRVPVEPEACLESDYPEIEFWHKVTWKSTRRKQSQESYIGNEEDEEEDDKQGKMRGNSRASKGINVSMRWVEEKNGEIIDGYRATYIRGFAFGLLFELLKQGKLPLKWSMASNDVKIWFYTEMARQIPELRYCADHWKMYQTRANAAGNAMKKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPW0</accession>
    <name>A0ABQ8VPW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_738638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="152" mass="17519" checksum="400252EF7CC763D0" modified="2025-10-08" version="1" fragment="single">VDNLLFQVPIQLLAAESAYFRTRMDQNDGLKEENPIQLDTDVSPEDFRQLLRVVCPPFNVEPEVFSFGQWISVLKLAKKWDMDEVRAYAISAIRKLPDIDPVDKIVLARTYDIPTWLGPSFNEILQRSRSLTESDVDKLGIPTIVRLMELRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRJ9</accession>
    <name>A0ABQ8VRJ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_932925</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4498994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="40"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4498994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="384" mass="41237" checksum="2A46788E5D5FF782" modified="2025-10-08" version="1">MVGQIRTRSQRSKWIIIGSVIGLLGIIAIGVGVGVGVSQNKSSSKTSSNTASANGATSNSSSNGDPVQTNPNDPSTFEKDPNLHQSFYALAYTPAGSQLPNCTNSLDDVIEDIQVMSQLTKTIRLYGADCNQSALVLEAIKQTKVDMQVYLANYPTPDDSTAYTRQRDEIKAAIETYGTDHIAGVTVGNEFMLNYLNANGATDPNSAVGNQGAAILIADINDTRSTLSEMSLAKTLPVGNSDAGSYFNTEVLEAVDYGMANVHPWFANVTVQTAAAWTAEFFEETNVQPAALLSNKPTMYIAETGWPSFSSDAGNANNGASDASEANLQIFLDTFVCQANQNGTGYFFFEPWKDAEFGGVEGWWGLFHSNRTLKRLQLPNCVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSR0</accession>
    <name>A0ABQ8VSR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_63696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="55975" checksum="0EF0859B995C1A25" modified="2025-10-08" version="1">MSQDSTNLSTIRNIHQWNSPERHSDHKQLSPIPLEIYLEIIDHVRPRDGIYISPQHVYECMNSLRNMALVCRYFCAQILPCLYKVLIFCPEPKEESLGNRRDVLSRTFIPFCQDINRGEAFAESLALEITQCDIRDWIDVPSETLDTSPVKASLDLLIKALPAMTNLASIVLSRTTLTPTLLESILRLEKLTSLHIQCCDLAGMTTKVIHDFASRVKLQTFHFFSNVMQDEQLVSSAGASEKELLSLLMNISTFGTDSWPLISAMIASDAVPSFQTLDIFHILDPAALCDFLCRISTLTSLTLDGVAPTEDSYSLVLSNLKQLRHLSCPPCLISRLSGSQNLSTLSFYTRAHQSEDPAMLASFIKAGLNSWKAFSQFISLRELCLPLIFMLLITVDPLYSPRDAKELKKLTVFSDGTAAISRDFIISDPIFMDGGPMDDNIKDAFFMWGLIRIIGHQKHFPKLEWFTFHGLNDRTWKWRNEGMSGKWRPFQLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU43</accession>
    <name>A0ABQ8VU43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endoglucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_108544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22278">
        <property type="entry name" value="DPBB_GH45_endoglucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22514">
        <property type="entry name" value="EXPB1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045239187" evidence="1">
        <location>
            <begin position="26"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="2">
        <location>
            <begin position="44"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="200" mass="20269" checksum="BA002879EA37707A" modified="2025-10-08" version="1">MAVRVANPVMRSFIVLFSIVAAVHGWVQQPSGSTSFTQYSGCGSPACGISASGYTAAINQLAFGSSPGLGAGDACGRCFQLTGTADPYSPSFTGPFKSIVVKVTDMCPAAGNQQWCGQTSSNTVNSFGKEFHFDICEDTGGAGAFFPSGHTALTGTFTEVSCSEWSGSDGGALWNGACIKGESAALWPGGVGCGNQGSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU79</accession>
    <name>A0ABQ8VU79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_753265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="17265" checksum="BD964CA5E3D44A6B" modified="2025-10-08" version="1" fragment="single">MSCPQCGYSSDRAPLPIPLYSTRVNNLLHTNDSPTEDEQKTLETFLGHGKSELQYLKARIISVKVLLEELERTKALLAKAVSEHETVLNPMRRMPDDLLVEIFLHGAGLYIDPGDYFPSARHSLNLNSPPWTYSRVCRRWRGTAMRTPLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUB9</accession>
    <name>A0ABQ8VUB9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cora-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_754183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF90">
        <property type="entry name" value="CORA METAL ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="52822" checksum="E91AF459DF164965" modified="2025-10-08" version="1">MLPENLKAPSRAASFTDLAALRKSKKGKTRDAIEVLPETEKFVHAYNPWFLDVASPTSEDMRAIGKLLHLHPLTLEDILQQDPREKLERFPKLGYYFISFRAIESRTIGTKIERRIDFGTDTGGDEGPFLESNVYLVVFNEGVCSFHFTDASEHIDRVRNRIISLEKTINMSSAWIAHSLLDSIVDSFFPFSDEIEKEVMAMEQLVYPSGTTTTASDVPARSESVLSESEKVVLAKEPLPALNEKNLLKLEVTLSGTRTHFALSRPPLPLLYRRFLRYIRSLWQPSLSNEKSIPSSTMITLRRMARIRRLVTSLTRLLAAKSEVVAQIRKRLLTGSGNGTSVNNDEAEVAMYMGDVQDHILSLQHSLAHYERMLSQSHPTYLQQLRTHVSLTKSGADKALVYLTTVSMAVLCLQTVIGMFSQNVNVPASPDSFHVFGIVVSVECVVLTVYLAVVRRWWLNAKKLKGKALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUF7</accession>
    <name>A0ABQ8VUF7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_864021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="660" mass="75977" checksum="27A547283145BA1F" modified="2025-10-08" version="1">MPKRSLPWSGNRENEYDKDYSPYTRVRLIMQNGRYEDELDLLRLKTAELQVQVTELDNEIDEIMNLDMEDVVSLKEDIRFYYNQYRQARLQVLELQEKLSETRVDGSPEKRPSSVVIPWRIEQADIEPQIRPDKKSSHLNTQEVASIASKDSGSSDHDAPTTVSILDLDNNGQPFNPPTSPNNDSNSSGHAQTPVTVTVNETGTTVNNDEIGTGQKLPYPSDAPSFGWFYDAFIYLNVDLGTHYSNLLSRWVEHERKNQWACPNDYREGFGKSRRPFLCNKWIRNRRYCRFQAEVDKDGCSTPEFTSEVWDWWVTLQPKRQSLGGTPPLLDESDAVLNSLDKYGKHAWPVLLACVKWWAIGLQHHLNNDKEEQKGKWVVLVKDMTKAFEGLQGILEKCFELSNLSDRDINWLSRQIIHESMQIRFTYEACLKEPISPSHLALFNRNPQKFGPTPDAIQLDMSNTCRRSEWNQAVIKLLAHKARFLTSDSSNSGIIVNWESMFAARVDRIISDARNLKLNADNKSKKARRATLLTKFQRRQRVVSIMIAQCRAIADEDGLVFWNYILRSLEILTHHGMSDEETGYDEDNGDEPFKYVFDLDYRHPAFSSLFHHVDNTPALYSDFFCPTGAKRLKRVSAQISVTRVPPHPIPSSFLREGYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUT2</accession>
    <name>A0ABQ8VUT2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_528232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32131" checksum="C5D8E008DEA06F2B" modified="2025-10-08" version="1">MNNMLPLNAVSAVIIISGEIGTTNDAWKGPDIPVVLRRTSLPSLDSGILDDDYAKKPENIHNIDVLKPHPDPPFKLPPPGNLSLHIRLGKMISTGRTGMLFDCECSVPSGNETLGYQVPPIVVKLARQYRSEDLTKEAIMYEGLQCLQGSAIPRCYGFFQFRSTDFFDFGPMSLLLLEKLGGHLTLGEPLPDGAESELETLCSDLASLHIIHNDLRYANILCVLSQEQGGFPSLPSPISGKSYQWRLVDLDCAYRTAQDLWGVQTYYNTYLSRVLDNVPFGCIVEPWEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV10</accession>
    <name>A0ABQ8VV10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homoserine kinase</fullName>
            <ecNumber evidence="3">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_900449</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-homoserine + ATP = O-phospho-L-homoserine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF1">
        <property type="entry name" value="HOMOSERINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861">
        <property type="entry name" value="HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00958">
        <property type="entry name" value="HOMSERKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="12">
        <location>
            <begin position="66"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="13">
        <location>
            <begin position="257"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4499335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="349" mass="37531" checksum="C7CDF3F1D470B985" modified="2025-10-08" version="1">MRQFTVKVPATSANIGPGFDVVGLSLSLHLILKVSVPPANEQAFVAPAITYSGEGADEVPLDAYKNLTTRVALYVLRCNGVRSFPSGLKLHAHNEIPFGRGLGSSGAAVIAGVILGNELGQFNLSKERLLDFALMVERHPDNVTAALIGGFVGSYLRELDEADTLAASVPLSEVLPEYPPDAGEDWGLNPPPPPSGIGHYVRFGWSEPIKAIAIIPRFELSTAKAREVLPSMYTRKDLVFNLQRLAVLTTALAQNPPDPDLIYEAMKDRIHQPYRKTLIPGLPEVTSCITPTTHPGLLGICLSGAGPTILALATTNFEKIAEDARQIFRIKGIEVDWKVLTIAGGSQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV17</accession>
    <name>A0ABQ8VV17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-lactamase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_753427</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF5">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="46"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="330" mass="35836" checksum="54B237F612E367E1" modified="2025-10-08" version="1">MADITLPKSTSTVSVKALNIASPRTSIPAALFVTPVKPGKERLASPDYAFLIEHPSGRKVLFDLGPMKDFSKLPPAMQGLLAQGGFEMSVDADITEQLKAGGVSVDDIDSVIWSHSHFDHSGDMSLFPAKTKLIVGKGTDRRTFPSVPDAMLLESDFAGHEVVEINWEKPDFTIGEIPAIDFFGDGSLYLLDTPGHWPGHLSALAHVKENSFVLLGADVCHHPGQLRPNPHIHKNFPCPGGILADLSKPILSIPEGFSMYADRASALVSQEKLTVIDAHPDVFVITAHDPTLDGVITLFPETLNDWKELGWKGKASWAFLEEGNKGYGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVV1</accession>
    <name>A0ABQ8VVV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_875760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF189">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="50"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="579"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="604" mass="64663" checksum="E2DE4C15B8931562" modified="2025-10-08" version="1">MSQTSTTRASIHTAEVAEVPNTNHNITSQPKEPQLTDQTRLLPPRQIIVVMFALSLCSLVTTLDQVVVSASLSTVAAAFNAGSVSAWIPAAYLMTSTAFQPLYGRLSDIFGRKAAIILAMGIYILGNLVAGFSKSIIQLIVFRAIAGVGDGGATSMVQIVVSDVVSLRDRGKFIGYAGAVTAAGYTIGPIIGGALAQHVSWRWTFWITLPVALFASIAILILLPLKPVQGDMRSKLLMIDYVGVFLTLAACTMIMLPLVWGGVTFPWKSAIVLGPLIAGIVAVGIFCLWESRVARLPLVPMYIFRHMTVVGVYICMFVNGFVFFSMLFYLPQFFQVILGYSSTRSGTFIIPLLVTVVSSAVGSGIWISRTGKYRSMIYLGFATFAIACGCMTIFTAETSRAVMVVLMVIAGLGIGATMQTTTVAAQASVERKDMAVVSAVRNFLRMLGGALALPSSAALLNNAMRVSMNTLSLPPSTISSIINNPSLLLQPSDLSKFGLTSSQADQILVQGYNKGFKDVFILNTALTVLAFVASVVMIRHKELLRGDEEALKKEAKAALMLEKAPGTRKDVVALGIGQGQIPEMNEDDGRRGDVEMGSVSSPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVY1</accession>
    <name>A0ABQ8VVY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Golgi phosphoprotein 3-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_892899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="411" mass="43973" checksum="9D5BD7158674D7A2" modified="2025-10-08" version="1">MASGLSRRRGAGHTTSSSSSTSPDSPPLSRSSSSNGVTNNSRTHAGSAFAGGSKIAWDVRDLPPDSSSAAASPEALRIGGTLPKLTLMEEILLLGLKDKQGYLSFWNDNISYALRGCILIELALRRRIAVVKDVVGGGRRRVELSEMIVEVVDERMTGETILDETLRMMKATQDPPIGSSTGEKLSISTWVDLLSGETWNVLKIGFQLKQVRERLAKGLVDKGVLRTEKRNFLLFDMATHPVADAGVKASLIRRLVEVLTARTTAVPEGALLPEGVQCRVLRTVCLVCAAYTASVLDGAMGTSYPSILPLGYEEREGAFARADEILGEFSVWPWGTGSDSGSTPASRKRISSSRIATGSSSDPSRESVLGLVAEARKEMGRIAQGQDDGQDLCLELVAGVLEVLGRLDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWD6</accession>
    <name>A0ABQ8VWD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="179" mass="20341" checksum="8851E18BDE4459D0" modified="2025-10-08" version="1">MLKHSSSLGSRTSKLAVAHRSILGPFRGYRRLRASTGSTADARDAALIKKLESQLAELKKTIKEEEENAHKFLERHASGEQAKADKQNQYVWFWEKALSNDDRKKLAALNIKSLDDLQAAYHEADVAMTTPPFPKSEKLDPRLRIAHNLHMRIPEKIAAARRQSTLSRLNLKRFWGGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWX4</accession>
    <name>A0ABQ8VWX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_355935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="589" mass="62886" checksum="BD0667A23844576D" modified="2025-10-08" version="1">MATLALRLNELAAANAQGLLDDDEYRILRQDAFERYAGLGDTEGSSGGIVFVEPSITQSNRSTSSAQPRPKKLNRRPSESKMNIFASTSSDKGRTPTSNNVISSFIRRATSPLRSSESPPGPSKFPSISKKNTQESTLSRSSSRKNLNSGHSHSYMHSIPDPHLLSPPTSPTRPVHTPSQRTAAKGSSSPVKISSSSSKSSTQTSLSAMSNHDIFEDGGLFTSIDIRRAISDLDEDAKNVLRAFDELEESAFKRTKSRNQSSRSHSAAPPSSFSLNLLPAPTMQHRSRSDSAATATVSGRSAASADDSLSRSGHPRLRSQSTTSIQPVTILDPPHKSNSNLGTPHSTSSRTPTLHRKGSVSSLASSIFSLKAKASMPSLPSLPSIPSISTMPNITRSRSGSVASSTTSSNPSNSFFPSSGKSVEGLPPMSPEWSSFGQGRSSTSTGASSIHTTTSTSSTGRTSLSSGHGHITTTSNTPSVTATPPVHRSRSASEFSSSSSSVHFRGNTMSSGRAGPSGHSKYRSGERERGRTKGDPDGLDDLDELDELGEIHQIQQRKRDVIGRYDARREYLKARLRGAELHEKVVKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXB7</accession>
    <name>A0ABQ8VXB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_807733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF5">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="440"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="658" mass="72638" checksum="306FCD78D73427A2" modified="2025-10-08" version="1">MSETAPYGTWESPITAESITGNSTTRDDVIVDAVTSIIYHLESRPAEKGRCVLVESETGREIVGKDVNVRTGVHEYGSASAIVHDGIAYYSNIIDNRVYKVNVKDGSPAEPITPENKAFRYACFNIHPYNPRFLVSIFEDHTVNTPSTVVNTLVIIHTQAKTVAPLVSGADFYALPKFSPDGSKLAWQHWDHPNMPWDNSQILLADVTLADSSLTLSNVTTIAKEGSNGFLAWANRNTLCWVCDVSGFGNPWKYDVSTKKAGPIFPSPVKEEFGAAMWLFCFFPFVIVDDVGKLGIFKAYRDGRAVLYRVDTETGDREHIESPYVVVECMRSVSKSKGQFAFLGTKVDHSEKVVVGTIRDTASFTAVNSGTISKGPNFDPSLVSIPRGIPLKAPPNDELLHVIYYPPHNPAYAGTSIEGEKPPCVVNVHGGPTGMAQQGLSWKIQYWTTRGFAWLDVNYGGSFGYGKEYINRLWHGWGAVDVEDCITASRLLAKPPHSLIDPSRIVIRGSSSGGLTVLNALCNSSDTEVYAAATSLYGVTDLVGLVKDTHKFESQYMFALVGGSPEDTKPFQKRSPINYVDKINRPLLILQGDIDRVVPKEQAEVIYNSIKKRGGVVEYKLYPGEGHGFRMKESQCDAFERELDFYQRALGLRESFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXE4</accession>
    <name>A0ABQ8VXE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_808443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037548">
        <property type="entry name" value="Bqt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044:SF1">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="2">
        <location>
            <begin position="35"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="372" mass="40650" checksum="CC690CA5B93A8C8D" modified="2025-10-08" version="1">MSRPPLPFHCTNANIQSILSSGNLPPVKYQILNCQGQDILVGRLKIETSTGSGHAFILRRYDTGAVSLTTMFRAAFPKADEQSEKDEVQWVKDSYDLSGNNGSSKDTSITRLAGTWVGPELARELGKSYLLGDLISLVVDARPDPNGNYRRSGKGAAATPRPPSSTDSAVRNQPTSPSIAPNPSKRRKESSPAPAPPPSPPPERRNPPRRSNRTKSPAPKVSVLPLVKTPSRKAVRREVKEEEVVTPGGSDETAVDEDAEAVEDVAGEQLRQQDIEEQKVLIEGLKAKRNAAMKASDGDIDGSDKSIVKRVREEEEEALRFNFKEPEVGERAISTNRRVDGYFEEPRHKSLAWGVVAFAFGMGAVTFLPNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXJ3</accession>
    <name>A0ABQ8VXJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_899352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="35566" checksum="E55560E02E1A8A5A" modified="2025-10-08" version="1">MVAASFWTLFRQFFPPASKWSFADMPDLTGKVAIVTGGNVGIGKETCKQLLIKGCTVWLAARSQSKAEKAIAELKEETGKEALFLELDLSDLKAVKESAEKFKSLSPTLHMLICNAGVMAPPIEQLTAQGHDLTFGVNVLGHFLFIQKLLPLLKTTSNSLTDTRIVWVASSGQYYFHNLPINYDNLKDTPSRTKLGVQDLYTQSKFITVMLGIYMGKILAEDQDSNVICIHLDPGNIKSDLYRRLPSLLVTIMEWLVLKPTAMGAITQLFAATAPEASQYNGKYLRPWARLGEPHPLTKDETEQKKMWDYCIAVVKGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXT9</accession>
    <name>A0ABQ8VXT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF45">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="364" mass="40352" checksum="C5FE30A778AA40B2" modified="2025-10-08" version="1">MSMGTTTPSISLAADVDTIPGIDEATRVALRRLRGRGFDETNLSLHRQQLAAVLVLLYSDSTGSIQVLLTTRSKSLRSHPGQTALPGGRIDEEDREPKVLWGAFREAYEEVGLPFPSSLIIDSDNDIPHIPNIHILCTLSPHISQWGIIVVPVVAYLSGPVSSSASSPPSHTYTLTPTLTLQANPTEVDRIFTHPLESILDPFSPQSTLSSRDLAEKGSEDWPYDEELYNYTDRLYPQLGPNHNNNNDTTDNIPSSIYRMHRFRSVASPIKGLTAEILVCSLSQVFPSHSNLFVRRFVSYHHLSPSSLPSSFHLYPFINLSLHPFVLYRFLASSIPFYPSSSAQPTSPMPVLPPRRLSNTLLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY08</accession>
    <name>A0ABQ8VY08_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_197556</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467">
        <property type="entry name" value="ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467:SF0">
        <property type="entry name" value="PROTEIN ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="36443" checksum="6A4B2B88D0FD930E" modified="2025-10-08" version="1">MPICTTCTRWLPYLYTVYQSAYNLRLDQCPNCHSFADPYVEHDELTLLIDLLLLKRAVYRHLLYNRGSGPRREDGTIGKDSDEQHRITSGRELSRWRLVLRLGSTLTFVDAFIRWSHLSVRPASSELEKSLILSPWAIETISGFATIFFGCCIETIAFHAGVVFACYSVLRALNFRFWRSQSDIRKEFRFSLIPLTLFYSSFTKLFFLFLLTIWRPSRSPLEKDGNIPVSMPFNFDILSVLNFMTENNLDREWIVRNVMGGMSAGFGLRVILDINPLFTTVIILFGWMTKTFVSRLISGWIGSNVATAEAWLASSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY64</accession>
    <name>A0ABQ8VY64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C8R41DRAFT_200552</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ4501336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="435" mass="47348" checksum="50B07B16658AB350" modified="2025-10-08" version="1">MYLQPRGSSPSIANSELNDYYDQLPPPHRLSSFSTNSTTHLAETYTDGAPIRTRPYYGDRRGEFPETPFVEEKAFTRSSRKKWIVWGLVVVGLLAVAGAVAGVVISQTSKSSSSSGSNLAITGDPSQFSKDSRLKQSFYGIAYTPEDSIYPNCNIQLADVVTDMQLLSQLTSRIRLYGSDCNTTAMVLEAIQLTQVNMTVFIANYPDATDDGVAYNRQKTAIESAIQAYGTDHIGGVTVGNEFILDYLDANGATDPNGSVGNQGAAILTPLIDDTKSMLQSLGVTLKVGNADAGSFFNDKVLADVDYGMANVHPWFANVSIDAAAGWTWDFFEDTDVALAQNLSNKPDMSIAETGWPTNSSDAGNESNGASTASEANLQTFIDTFVCQANANGTEYFFFEYFDEPWKTQQFGGVEGYWGLFYSNRTLKNIEIPDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYT8</accession>
    <name>A0ABQ8VYT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_813248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="11343" checksum="EA9E6D50DCAFFFCC" modified="2025-10-08" version="1">MSAQATFKSIKSLVPLLDRVLVQRFKPETKTASGIFLPTSATSTPLPEATVIAVGPGAPNKDGQIIPTTVKAGDKVLLPGWGGNAIKVGDEEYHLFKDSDILAKIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYX5</accession>
    <name>A0ABQ8VYX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_805092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="474" mass="51762" checksum="BD1D93DDA70A9AB8" modified="2025-10-08" version="1">MEPGPSTRNAQMPFDDFTRTQGSFSSSLVSKLDTVVWQMPPPSNPALQRLMDKANKDVSRMNPPPSESNWNFLPSIVAPDVVGSSSRPFTRSTDKRLHSITSFEINPAIAKLVDPVLLKSVADAASQKAQERSRTLGLVMKRRKSNSKSTKAEKFTTGKSRASRAVNSGMIEKSRSVPKRKERGSAKEISGSSLHPKSLTHECSTFKRPVFDDSFSIPSSSTASPELLDDSMSIDETHSPDTSLMSPSPSFIPAMKHPPLKRGTSPNLLPLLTTRLLSHHTTLSAKISNAAAVDVGCHSPLMSNGTRAQRVRNAQSREARSVPIVTSKIPPKAVQVPALSVVPPPMSHPLPSANPPALGMRRVNSFPAKNVRLADSSNNIGVVKDLPTKQRPFKTPFLPTTQRSNTGQTLAVNATYLRTEKSPGSRMNDVHREALARTIEETEPHGMVCDDAETSYEHDSFDMDALEETLKQYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ66</accession>
    <name>A0ABQ8VZ66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_748372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="127"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="37600" checksum="A002EBA27B1366DD" modified="2025-10-08" version="1">MDALYAGTDFSSLNWAEQKWVAWYVWWGNPIIATGMLSFLMHEIVYFGRSLPWIIIDAIPYFQKWKLQPNKIPTPQEQWDCTKQVLWAHLTVELPAIWLFYPMSEFVGMKTYQVPFPSLSTMSWQIFFFMFFEDLFHWAAHRALHTPILYKYIHKIHHKYSAPFGLAAEYAHPAEVMILGMGTLGGSLFLCLFTKVHFISFFIWVIIKLFQAIDAHSGYDFPWSLQHILPFWSGAEHHDFHHMAFTNNYSTSFRWWDRIFGTDDKYLVYRERVQAAKAKALSKEDFLKAEQALMDEVLAEGLKAENEVEERSSRKVKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZK2</accession>
    <name>A0ABQ8VZK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_976750</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="10">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="11">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="626" mass="66745" checksum="9691A1BA5AC41515" modified="2025-10-08" version="1">MRYNTLTILAALLGKSFSTPLKRQVTGITSDAAAFAQSSFDYVIVGGGTAGLVLAARLSEDATVKVGVIEAGETRFDDADVNTPAYLGQALFNPLYDWAYETVPQATLNGRSVSLNLGKMIGGGSALNFMIWQRGCQGDYDNWSQLGIEGGWDWAGLLPYFEKTENVTPGPLDTPYNFTEPSGSGDGEGNSGPLPVGYNNFYSTIEGPYAQALLSLGVPQNADPDNGDTTGLFNSAASVDPATGNRSYSGRDYLLPNVGRSNLAVLTGAQATKIQFTQSGGNATATGVQFTASGTNYTVSSRKEVILSAGSLHTPQLLELSGIGDEARLTALGIPVVIANSDVGENLQDHQTLNSGFLLNDPDVPTVDTLFSNASFAATQEELYLTNHTGFFTYTPSALSFHPLQQFWTEDELDTALAQLQTEITQANLSTFINKQFQLQIDGIKQGAVGQMELLFVAGVLGASSTDQENFVDMSNFASRPFSRGSVHINTTDPLAPPLIDTAYLQFSFGKYYLLYQRHITRNLSQIAPLSSFIASPLNPSANVTTDEDFENFVIENVGTEWHQVGTASLGPLGEGGVVASDLIVYGTSNLRVVDASIMPMQIGAHIQATVYAIAEKAADIIKAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZK7</accession>
    <name>A0ABQ8VZK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Tubulin gamma chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_15741</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02188">
        <property type="entry name" value="gamma_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002454">
        <property type="entry name" value="Gamma_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01164">
        <property type="entry name" value="GAMMATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="10">
        <location>
            <begin position="48"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="11">
        <location>
            <begin position="248"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="452" mass="50720" checksum="3EA56A1246C29372" modified="2025-10-08" version="1">MPREIVTVQLGQCGNQMGSVYWQRLCAEHGISKEGILEEWATEPGDRKDAFFYQADDEHYIPRAILVDLEPRVINNILTSPYANLYNPENIFVSKDGGGAGNNWAQGYAAGERIYEEIMEMIDREAEGSDSLEGFMLAHSIAGGTGSGLGSFVLERLNDRFPKKLIQTYSVFPNAQEGDVVVQPYNSLLTLKRLVNHADSVVVLDNGALARISSERLHVQTPTFDQTNQLVATVMAASTQTLRYPGYMNNDLVGIIASLIPTPRCHFLMTSYTPFTSDQIDKAKPIRRTTVLDVMRRLLQPKNRMVSTTPSKTACYISILNIIQGDVDPTDVHQSLLRIRERQLANFIPWGPTSPQVAITKRSPYVATNHRVSGLMLANHTSIASLFKRMLDQFDKLKRRNAFLEQYKKEKMFENGLEEFDDARATCEELLNEYKSCESPDYISYGAAEGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZR0</accession>
    <name>A0ABQ8VZR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_862113</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="220"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="509"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="711"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="712"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="924" mass="99997" checksum="C20627F33779804D" modified="2025-10-08" version="1">MPPSPASSSNSLLYPGEQWPSAAHTRSSSSKSVPHLNLPVSSQDELLLPPMSPTLQDSTPAPTSRFRFRSRKSSQFGTAPVTPAEEISQSSKQHHTGPLHDLKRFLHHHIPHSPHHSSHSTNRASAAATPHQPPSPDPFKEKGKLSTMMRRDKPNGKDRIPSPSESHSPTSASASDSEFNKPRSPARPAGYNSSHHPQISSHAIHSLQDATHAHIHKKYGKWGRVLGSGAGGTVRLIKASHKNGGTIFAVKEFRPKRNGESEKEYQKKVTAEFCVGSTLKHANIIETVDIISENGHYYEIMEYAPYDLFSVVMSGKMCRPEIYCVFRQICEGVEYLHSLGLAHRDLKLDNCVMTTDNVVKLIDFGTATVFHYPGKTTHTKAKGVVGSDPYLAPEVLADEEYDPRKTDVWSVAVIFLCMVLRRFPWKSPDVKNDASFRAFVNAHPDLSVPKTTKPKALTSTSQVELGLGQTIKKPPIPIRHSTMPSEMKIAAASPRKELVNSIEADQNLASPTASSYRVPSPSSSSFSSDYDDDDESERSDSQLSHTPSVEQRNSERQFALATSPRISRSTATLPAFVLGAIQNDLYNELSIAGEVDMDPSVRRFGRPGNSTESLPVSPSRPFGITNGLFNGGINTAPATPSSAVPPPASPIGLLSAPYMSEDELPTPKVANGIIPLPPASALSSRTVRARSATLNSIGGPELLASMKEDHSVSNGIPTTSPMASAPINSPTSNTIPNITISEREPETPKEPPVPEQTTRRRQRSDSVTTFHGGGAESIFRLLPRETRPALRRMLHVEPGARCTLTDLLKGRGKHGNLLCGCQAGFPHLNIDGSISTLTGTTIGGGKEPGLNGSVNGDSGTNSSTSTLSTVHQPYCVDHDCEPEEEDNGDPWLTSIIPCSTLGVKPDHVHIKVAIDEKAGKRKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZT7</accession>
    <name>A0ABQ8VZT7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II transcription factor B subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">RNA polymerase II transcription factor B 38 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase II transcription factor B p38 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_729666</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16573">
        <property type="entry name" value="RING-HC_TFB3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004575">
        <property type="entry name" value="MAT1/Tfb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00570">
        <property type="entry name" value="cdk7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17121">
        <property type="entry name" value="zf-C3HC4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="56"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="380" mass="42534" checksum="C5A97EF6BBDF0C73" modified="2025-10-08" version="1" fragment="single">GWLQGRTVRKGGHSSSNSHTRSSTPQVQSTSTTIFGGGIKDPSGRTSEYFSMDDQCPVCKSDRYLNPKLRLLVSSCYHKMCESCIDRLFTLGPAPCPICNKVLRKLAFSPQTFEDLGVEKEVAVRRRIAKEFNKRLEDFDDLRSYNDYLEEVEDIAFNLINNIDILATEARIAAYKAANAALTSLNLQREEAEALALKEQEDLERREREARAAQLAQQEQQERDERQREERELIDKLETSQKDAHKIVAKSRIAAAKRSSARAASSSANSGLLGMSFGADYAKLLKTRTNKVTNNVPDEPHVPFQDDWYAYDDLYTVRVDGYDDIISEAVRKDREGIMRAGGYKVEEAWNRALLTAVAGLNVVPLSGSDQPKSLGDADVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0E0</accession>
    <name>A0ABQ8W0E0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_811218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="237" mass="24567" checksum="73CB6069FFDF8373" modified="2025-10-08" version="1">MFYPKASLIRLVSLLSATTFALSFRILPVAPRQATDADFFNPLLNGGSMLDQVPGVLGEPLNVIISAQSSPDVLTLDGIINFAKAIGFSTECLGIHSGAPQSANLGDGNGWVNQTIELREDYGDSVLGTCLESLIGGNHFRVFVQNGTEHPTGALFLAVSTEENVTEGHTTAPDGYDTGRDLFSAAAINNGGTTSFGGTTYSTVGTNITGLIQPGSTGIEDGIATDGIVTLLTVTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AYS4</accession>
    <name>A0A9W9AYS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Iron-sulfur cluster assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_501931</name>
        <name evidence="9" type="ORF">C8R41DRAFT_775670</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000004">
        <property type="protein sequence ID" value="KAJ4492998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AYS4"/>
    <dbReference type="OrthoDB" id="1925777at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1010.10:FF:000008">
        <property type="entry name" value="Iron-sulfur cluster assembly enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISCU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU N-terminal" evidence="8">
        <location>
            <begin position="34"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4473491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4492998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="188" mass="20333" checksum="BB137D09B860F43A" modified="2023-11-08" version="1">MFRSAISRTASLSASFTRQKVSSVTLRPVMSRGYHEKVISHYEKPRNVGSLPKNDIDVGTGLVGAPACGDVMKLQIRVDENGIISDVKFKTFGCGSAIASSSYMTERVKGLSLEEAGKIKNTEIAKELCLPPVKLHCSMLAEDAIRSAIRDYKSKRNTMTNPKQKGFIDVSQSVVTGETVATAHPGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B205</accession>
    <name>A0A9W9B205_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8J55DRAFT_413501</name>
        <name evidence="6" type="ORF">C8R41DRAFT_318583</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000001">
        <property type="protein sequence ID" value="KAJ4496289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9B205"/>
    <dbReference type="OrthoDB" id="10255148at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="201" mass="23958" checksum="62EC65E849F0B5D4" modified="2023-11-08" version="1">MGGYKYVTELYKKKQSDVLRFLFRVRCWEYRQLNVIHRASRPSRPDKARRLGYKAKQGYVVYRIRVRRGNRKKPVPKGATYGKPVRQGVNHLKYQRGLRSTAEERVGRRCGNLRVLNSYWINQDGVYKYYEVILVDPNHKAIRRDARINWIVNPVHKRREARGLTAIGKKNRGLGKGHRYNHTPARSTWKKHNTLSLRRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DHU6</accession>
    <name>A0A9W9DHU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mago nashi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8J55DRAFT_521547</name>
        <name evidence="5" type="ORF">C8R41DRAFT_815404</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mago nashi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000029">
        <property type="protein sequence ID" value="KAJ4471391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DHU6"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11295">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1560.10:FF:000001">
        <property type="entry name" value="Protein mago nashi homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1560.10">
        <property type="entry name" value="Mago nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004023">
        <property type="entry name" value="Mago_nashi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036605">
        <property type="entry name" value="Mago_nashi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638:SF0">
        <property type="entry name" value="MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638">
        <property type="entry name" value="PROTEIN MAGO NASHI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02792">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89817">
        <property type="entry name" value="Mago nashi protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4471391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4499361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="149" mass="17589" checksum="49BB15DF67F31B29" modified="2023-11-08" version="1">MSSQDNDPFYLRYYTGHSGKHGHEFLEFEYSHGRLRYANNSNYRNDSLIRKEMWISPLAVKEFKRIIEASEVTKEDDINWPKKNIVGKQELEIRIGNDHIAFETAKIGSLVDIQDSEDPEGLRVFYYLIQDLRCFVFSLITLHFKIKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX83</accession>
    <name>A0ABQ8UX83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_891581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000138">
        <property type="protein sequence ID" value="KAJ4464589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127289" evidence="1">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="168" mass="17863" checksum="6DAF207656A29AC7" modified="2025-10-08" version="1">MAPSFTSRLFTAAAILYSAFHASAAPSTRQVLETSHGILSAPSSGVVVSQGSSFPFEFQDSNWCEDGYSSISVWLTNYAPTYLNVNSTGQFSEGEYSYYFGSYLIPNFGLPVLSGSTPPPSSLPLPESLNLSAGDEVYLAVVETGTSCPPGLHIPPQYELTETSIIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXD8</accession>
    <name>A0ABQ8UXD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_859451</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000135">
        <property type="protein sequence ID" value="KAJ4464727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051752">
        <property type="entry name" value="Mito_2-oxodicarb_carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46356">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46356:SF1">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="9"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="103"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="196"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4464727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="296" mass="32460" checksum="B5BB6D5E7BA2A97A" modified="2025-10-08" version="1">MSEQPKKPLPFVANFAAGAIAGVSEILTFYPLDVVKTRMQLSTEKSQGFVGTFRNIVKEEGVGRLYRGLVPPLLLEAPKRAVKFAANDFWGKTYLDLSGEKKMTQQLSILTGCSAGATESFVVVPFELVKIRLQDKNSTYAGPIDVVKQIIKKEGVLGMYNGMESTFWRHLWWNGGYFGCIFQVRAILPEAKTQQGTLFNNFISGAVGGFVGTMINTPFDVVKSRIQSAPRLPGVAPKYNWTYPSLAIIAREEGVGALYKGFVPKVLRLAPGGGVLLLVVEFTLGIFRQALGPPYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXQ3</accession>
    <name>A0ABQ8UXQ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_859764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000138">
        <property type="protein sequence ID" value="KAJ4464601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF39">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="124"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="209" mass="24587" checksum="9E4D85FE45AF9D44" modified="2025-10-08" version="1" fragment="single">MIPVPRVRRVMKLEYLFFIVEDYIEGPTLAQVWSTYSLWQKIHVAFTLRSYIRQLRKLKAPRGAPPGPISNDGPRVCTSPLFGMLDLDQGPFASYADLASFFNEKAKLCYDYNNIPEDHPCRRQKFDDSEELVLSHQDLNPRNIIVGLDGTIWMIDWGWAGYFPPWFEYVAMKEKSLSEHYYQYWDLFIPFICGPHFEHEIWHLSMARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYB3</accession>
    <name>A0ABQ8UYB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000122">
        <property type="protein sequence ID" value="KAJ4465752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="547" mass="61596" checksum="9FCB740C05554054" modified="2025-10-08" version="1">MRHNKHSLFSKHKRKISGKLRSSSMAASQKIGSSSKAKASSTGHETEAEEGMEHNSEEDLEEPEDSHVAQVLRNITQKGKGTPTLARQAVVASIKASSTSSKVSKAREETNRTKSQQFKKKAKAEGEERTEFKVMSLSIYPVGTYLTDEGYFPLQKPTKVYRDLTSLVDVGCAQIATIGQPMVFDRKDTYEEVADKLRALCPLVMEYADSRFMYRKKSNPEYPKHDSDPGHAYLPEIILCKKDRTYGMLPLTGPSAFFPDGEMLWRIATKHGSANKNELTREPISKRRLGLFQEAIQKAKQMNVAPVTAFYTLNENTELSTEEDIIGEEGEEEDTTDEDQRDYQETEECKETEAEETTKEGTVHGNSEEEELVEDALRPPFTQKRLRSESQPSGEDEHPAKKRKGKSHGSFRSYSSSERQSQTETEEAEEDTNTPKPRSRAFLRKTGSPHMRSILRNADRARKFFGVTVDEVEDDLGFCTDYSSDQEYASDLFQKPTPSTPQVNTSTASTSQASTSTSSNSMAAFLTYYKPPLSDKSRERLDPWKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYE9</accession>
    <name>A0ABQ8UYE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_782713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000139">
        <property type="protein sequence ID" value="KAJ4464567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-haem dioxygenase N-terminal" evidence="2">
        <location>
            <begin position="30"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="1">
        <location>
            <begin position="199"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="42297" checksum="59454657DB257BD9" modified="2025-10-08" version="1">MPVPVPVPELGSYNYVAETKANLDWADLVTVDLGEISTPEGKRAQADILLSALKEKGFFYVKNFNISQERVNRQFALGKAFYDLPQEEKDEFAVKGVEQGNYNGYVGNRQRVVNEKSGLRSRVEVYNIPKFNGDFEHHHPAIIEEHIEEIEEFARSLHSEVLDPLFVLLALALELPEDYFTKIHQYPVKSEDHLRYMKYGKYTPEENKLIDNWVQGHTDLGSFTLLFRQPVAALQIRYPSTNEWKWVKPQDATLTVNACDALQFLTGGYVKSTIHRVAVPPIDQQHVDRLGLLYFSRPHNDIPLATIRDSPLLQREGYTGNDLEVSGHPVPTMEEWTFAKQKWQRTGYDKPEHKTAQILPGWKEKVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYS5</accession>
    <name>A0ABQ8UYS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6589 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_783824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000162">
        <property type="protein sequence ID" value="KAJ4463460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046496">
        <property type="entry name" value="DUF6589"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20231">
        <property type="entry name" value="DUF6589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6589" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="109" mass="12435" checksum="5DA8916CD8C378F2" modified="2025-10-08" version="1">MRDALLSWECANAVTSGDVGCVWEVLKVMIFTFSGSLHSKYASYLLETITSLELELSCAFRDALLQTMVINLNGKTGRFSPCDLIQEYFNRLLEFIVERKGKEFDHVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYU0</accession>
    <name>A0ABQ8UYU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_890810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="53"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="52593" checksum="79BCC763926FD956" modified="2025-10-08" version="1">MATPTPSVSSSSNYSSVDPRLRTTFSLVKWDKLASLACTLSQLPPGNCHWGEQLSGGYNLVRFLHLHGNQESIIVARVPLRSEDAMSEEHSSAISKRIESEAVTMKYVDTRTAIPIPHVFHYNAHAEEDVGSPYILMSKVDGVPLSSVWDDMDDDRRLIVLRQVIDILLELWSHRFDKKGALFDGTDGSLCIRSNSLFVSPDNNGTRHRLQTTSYLHAADFWLAYANAQLYDIDESDFGSDIKSFTHSQAWFMRSLIPALFDPSIDVHGFPLSPGDFHSQNIMIADVNSSHPRITSVIDWEFSGPDFVSSFAQYPLFIVDHPHWKSDNPLRERNVRDQATFDRLIREAERRRDPVNDNVKLSRLISNSYGIYLFQQAMYYPGMYSSMYPLLFTHVFGDDDDDNFSTDYYWALMENILNKDKQQFDRENGVWLEAREILGEEAVRPHLTRTEFIDLIFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYU1</accession>
    <name>A0ABQ8UYU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_76125</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF51">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="72"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4466211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="519" mass="57267" checksum="4668580A0AFBEE45" modified="2025-10-08" version="1">MSQDSLSTTPPTSSTMEKRSGFERLSGNVVGNSKSDLGISPKSEQPQALEDEVIVVSEEELRKIHRKIDKRILPWLCITYLVMRIDVNNISNAAILNEEQGDDIKTQLKLTAQNWAWAIACFYYPYGFLEPISTMFIKSTTPSFWIGRIMVTWGIIVCCIASVQNYAGLISTRVLLGAAEAGYYPGVIYYLAFWFKPEELALRVAVFYSFGQVSGFVGGFLAFAVSFANGVLPGWRWLFVIEGIPAILMGITTFFILPDFPQTAKFLHHRERDVIIQRLSSGAPSKMAKTWDKDQVLRLFADPTFWTFSATWFCHAIGGFGLSYVLPTVIYDLGFTTTALSNVLSMPPSLATFVLLNVLGWLVQMRKWNPYWVAMGLEIVNIICYVLLLTVDVVVVRYLALLVSTATAGSVYPILWPNRVKAAHGTTAAGIAIGITNAVAQFSGILGPQVFLSVYGPTYKVSFLVCVGLLAGAVVFIGMSGALLGELGLGKFEFGRTENTQMEGSEQDMMDKDNSLYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYW9</accession>
    <name>A0ABQ8UYW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_703270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000135">
        <property type="protein sequence ID" value="KAJ4464704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="26372" checksum="8AA60DC99ABA2A29" modified="2025-10-08" version="1" fragment="single">FTAKEMNHPRGDFTACAAGFSYGGGREHPGNVRITGEGNKAAMDELLNHEDMVRLVSFTNSLYNSFNHKTYVEYKETLESHLVHDPRLRPTSSKTVFATTTINFGPRIIVPPHIDGGNTGHGWCSDSSLGPYNPDKGGHLVLWNLGLIIRFPPGATVLFPSALITHSTVPIQPDETRYSIVQYSAGGLFWWRNNGWCSDKVFLQKASKDQLKQQKVENAQHWSMNLEKFTHWSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ51</accession>
    <name>A0ABQ8UZ51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_898727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="49529" checksum="A09912E087A5ADD0" modified="2025-10-08" version="1">MVTADNLNLDVLESIFFYLSGNDLSSVALVSRSFFAGVIPRLYRRIMFRLNHAKRYPRVMSPFNAILAHPSLATHTRHIGILHPVFLSECTRALSLCNNLQSFQCTVNAVPPLLPSLQGKERLQDLRIYANLTTLQSEKLAEIANLTNLCLDFGSWNVLDVLPRWTPKFAKTLTSLCLYMANELNETVLDKVLQQLPELQALHIVGCGQVDHVTVLRLVSYTPRLESLSLSTTESLAPISQPPPSLQHLKHLALDTRYSMMSSPAPQVLSSILNHIQASAPALLSFIMRLPELKITVGNEFIEELVKLHGHTLRTLAFIDCGVSMESIATITESCPNMERLELPIPVKDMSAFAKSLDKATNLQTIIDTNTHSAHGHGPNVSLVRDNVRHLMMHGAQLRKIVSGKRVWKNTLATSIDLSLERLPAYASGTHWFMPRDMSDFGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZJ1</accession>
    <name>A0ABQ8UZJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="21279" checksum="C9285C6BB827C741" modified="2025-10-08" version="1">MSSTNSVPPTASGDANPSSSPESYPEQHHAGAVGYGPNYRQGASLGDKLTGLKEELKGKVTKNPGLVEHGKEMKSGELKKKEEEEDMNNLDPFGTADDDDEKKKEVDSTGSIAKRDAQGQQVNSDGAGVTTTETESGVAKPRDVKYIDEDRSGEHHHHHHHHHHNNNHNNSSTHHDGSSNANAVASEPGQIARDAVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZN5</accession>
    <name>A0ABQ8UZN5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphonate degradation operons associated HDIG domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_779821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052567">
        <property type="entry name" value="OP_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40202:SF1">
        <property type="entry name" value="HD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18161" checksum="97F7C30DC6C81806" modified="2025-10-08" version="1" fragment="single">YIGESISQIEHCLQAAYCAKQAAVLAALLHDCGQMCVPFSCTNMLLPSGRSVGKHGHDVIGGLYLASLGFPPEVWELVRDHVVAKRYLTAVEEGYHHALSEASKLSLGFQGGPFSHSEIKNFEQDPLFFEKVQMRRFDDAAKIVGARVPPLASYKDLAMRWLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V091</accession>
    <name>A0ABQ8V091_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_859108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045750242" evidence="1">
        <location>
            <begin position="20"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="124" mass="13138" checksum="2D90016618F753E0" modified="2025-10-08" version="1" fragment="single">MRCNFVACFVLGLATVVYTAPVVSRRDAGFVPFAGLTSPLNQNGLASMASLETRSVAVVFEFKDQHAAEAVPSTFRLPFTSSKAIKDQAAEVSAQSTVKKLLQTLGFEGQLKTGSIFGGTPHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0P5</accession>
    <name>A0ABQ8V0P5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="42693" checksum="8DEB45DE198C1813" modified="2025-10-08" version="1">MDIPMVGMFLDVHNSNCLPWIPVYLEAKMPLMLYWGSKDNWSIHPMLENVIPTPTATIIKTLISEQTPYPPPPREEESFPVDIGISQHKYRLRLPRVDAISSETVVERQSRLQREKNAEKDRAPGRKGARVYYWDLVEGVRVRTAVGRSNYEDIWERYGSRQRRYDSVADEWEVCTDLDPDDGPDDSLYNDDDDDSNFFISVQTHMNEETDHNVGAASSGSYLARLHPNKRTEADSLNYGFCEETEDVAYHRFGFLKQPRPDNRDVVLKSQVWSKVLGLIGCGRSPPSPGPDDYVKLQMCNFVTQLMDAVDLRTAPQVYDLAVRNSLMRPPVPFEVDVLCSFNGHYFLIQAQGATDHEPYLIVLRSAATVMEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Q6</accession>
    <name>A0ABQ8V0Q6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="20355" checksum="F518B7CA0C75D7FE" modified="2025-10-08" version="1">MSIAISRLAEAKQISCSHIVVLRSFDNVKFLIDKEELEVDTSGFPPATTPSYIGEVSSLPECSHILKILFQYVGTQSSQPVLDQIEFARMLEVAEAAEKYEVHKAIAAVQFELRKFFKSNSRELLYFALTYWNPQLVEEVAPFMINTPLQDIETLMKHCPRLFMDGCILILRRLHSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Z4</accession>
    <name>A0ABQ8V0Z4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000099">
        <property type="protein sequence ID" value="KAJ4468925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4468925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="339" mass="37700" checksum="07E169669753EFD3" modified="2025-10-08" version="1">MAYFWQILLNPIPGHHLLVRHSACLAMVSSQVRFDSLFTTASSIITQPITGKGPHLGHMLFTPEGPRALPLLFMLPDDDSAHLFSGSSGPLAPLPECSHLTSFDLMPSNPPPTVSLGLEASYYLQALQDNFGDVRHDASTQCLVGSADTRKGQGQEHYPTFNGLVARMRESLDTLKAASDLQTIACDMARFALDECDESFENVFVHCETMDKNTTIKYYMQGQGGHPQQYLYPDIALSCWGTGTEFSYHMCNRSTVDLAHFQGGSLAIPHRKHDPIVNQRSRQQYASWVVNDIPSRVSTPEWTDSPQVRFRKLEDLVTTDHELAWETGIPADSLLFSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V264</accession>
    <name>A0ABQ8V264_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_984600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000099">
        <property type="protein sequence ID" value="KAJ4468947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="49830" checksum="BD02050D1006A2D7" modified="2025-10-08" version="1">MDIDSKNNADGRRAPPLRVENTIDPPVTPPTHHRSRSPHQNAPTLTPPPFTPRKANSSMQQLLMSPCANRSLTGAVCPDGIKLIVRNAYLEDDAVHDPVTIMRNITTLLAASNPELSIIQMGNCTCDVTLRGRVVAVDIAVQTSNGQAFIHRIFGVYAPWDPGNIETQQFWPKLTQIICQTQTSWSLAGDTNATVNAEERSMGGGDARTQFIKFLNDVNGQDLWSLQPERNRMQHWTSRSRSNELSDGSIIDHVVVKAGSMVDGQISIHEGKDGFLPFTDHRAITARMIITSTGNANSFFLPHRIAMNRPRIKYPTVQEKHRHQEFQNLFDERARAKHLQDILVKDDESFMELYNETSKILLSSAETSYGRVPQYRSTARGNRVTNPEIQSQIGYLRSIGGAIRIIQNPDLYYLVSAKSRITYEKFRRKSQQQRINLLKYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V291</accession>
    <name>A0ABQ8V291_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_614983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="102" mass="11403" checksum="F492EA33169BE571" modified="2025-10-08" version="1">MRVFGGGSGNVEVVVLHLTPLLDFHLDHLCGGNRCHNDYRNSTNYNGNATHNDYRGSVNYCGLTTHHKFNVTFFFVRLIAIDEYKGSLNNNAAPSYPKPSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2C0</accession>
    <name>A0ABQ8V2C0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannitol-1-phosphate 5-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_897865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19661"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:61381"/>
            <dbReference type="EC" id="1.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the mannitol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00196">
        <property type="entry name" value="Mannitol_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023028">
        <property type="entry name" value="Mannitol_1_phos_5_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000669">
        <property type="entry name" value="Mannitol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023027">
        <property type="entry name" value="Mannitol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002646">
        <property type="entry name" value="PRK02318.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002652">
        <property type="entry name" value="PRK02318.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524:SF0">
        <property type="entry name" value="ALTRONATE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30524">
        <property type="entry name" value="MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00084">
        <property type="entry name" value="MTLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00974">
        <property type="entry name" value="MANNITOL_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol dehydrogenase N-terminal" evidence="8">
        <location>
            <begin position="14"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="217"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4470523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="402" mass="44960" checksum="ED22286139F85A0B" modified="2025-10-08" version="1">MPFEAISLPNKPVAIQFGAGNIGRGFIGAVLSQAGFHVVFADVQEKIVNALNEKGHYDVHILNGDTQIETIQPVSAIISTDLKAIEKIAREPLSIITTAVGPNILPRLAKPIAQIIRTRKEEGMGPINIVACENLQNATDKLREAIESELSDEQERLYLQDNIGFAICSVDRIVPPFSSENILDVGVEPFFEWTVDSNSLKKTDPDVVIDGMHATNNLDAYVQRKLFTLNTGHAITAYLGFLDNKDTILDAISDDSIHNVVSKALHESGAALIAKHHSFFSKEQHEDYIKKILKRFSNHNLKDEVSRVGREPLRKLRRGDRLLGPVEMCRERNLEHDTLLLGISAALLFHPTGVHEDEEANELQDRIRREGIEAVVTDLTGWAKDDEDLRKVIREYSRMKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Z3</accession>
    <name>A0ABQ8V2Z3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_746488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4471635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="139" mass="15987" checksum="621A0ED15AFACA2B" modified="2025-10-08" version="1" fragment="single">DHKKPVWWVNEIYFTPVKRPRVASGCLNFSPGWLAQGHHVSIFLVTNHCSNKDSTLEWLEQIDKLQILSNILIKLLHPELYEAGLTALSGLRHESQTIDRATRWNSIFTCLCVISSRISKQHRDSNGDNKFFDILFNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3K2</accession>
    <name>A0ABQ8V3K2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_897661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="344" mass="37158" checksum="A1CEBD68D9D7AC5E" modified="2025-10-08" version="1">MVLSATLNLTTISSKIVICGAGFLGKHIATALSRASSAGAVTHQIQLASLHPEKLYSALKSTHGIIPPATIDITDESTFLPAFSGASLVVSLVGIMHGSPEDFDRIQWKGAENVAKAAKEAGARLVHVSAIGADRASDIPYNRTKALGEEAVRDVYRGKAEKDVVVLRPSIVFGPEDDFFNRFSNLSQYLPFLPVFGGGKSRFQPVYVGDIARAVEIIARNDPSMNAMVGGKNIECGGPDILTYKEIMQLVLKYNHRTRPIVSLPFSMGKIQGAVMERLPVNLFTVTQAQVEQLKSDNVVNLSPPGNSMGAEYFPFNTLIEKYSIPGTRSTLASVHDILPKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4I2</accession>
    <name>A0ABQ8V4I2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_898152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="801" mass="92017" checksum="7B937A2D839465DB" modified="2025-10-08" version="1">MDRLCDEILQLIFYELHDPTPFTLLCRRLHQFSKDPYARAHYFLNRYGPAQAVFEALGHGKVVNERVLDILMTSGAHLSRYLVQIAIHHYFFTQTHFVKSKWVRNVPFPVFLHFMQLASTRYGEIPREKGQDDGSLFLTYLKESRYPPSLRSISWETIRDILEIYKFIPFSEKDPIMAQFPLVLAVEPRLLPYAVANGFNMDEKYRDFVFRKMFESSTLSDRTVETIADNVRELCRLDPSMFLSRTVAGEICMEARHNEVGYSALKLLANSGDLLFELPTLVEDLIKLFLKTRSLTLSSTQVNLRYLFTDFPSSDPVVRLVILLTAFLSVEREPDTPSCVPSLKAKLEPLKLGPITSTDMLNILVHPFTDRYQPVLDYMKSELANSEGKKGLNQVDIKDVIRNVSTRLLELDCKGKLLKKLYDGHSSIHETIVRAVMDKHQVKFDNLPNSEDIEACRSYRASLCKDNGFFGNTSDYFVVENPLNGETELETGSDGPIGREALTTMINREEQFPARSRRRTYNHQYTFYNHFEYLPSDYLSVAKWIKNSFGPKHSLTAIFMTHAVLNDNSNVRLVLFILVHYLRDSATSPVPITLKHFQLLAHLGRAANYTLFTAIQSGAEFFLSEEDYVDSKLDYSSRSNKSKHRTPRGSISHTQVSVVIGRTASTLVPADSGTAGKKRPRRSAAENRSYLIPDSDSEAEIMEVDLPEEKANLTLVHHLELWIKHLGDLQKSEQANVNNSNVDVTKTEFLKNLSTNLRALRKYANEKRKTSETLDMFYSDYEDEEYIYKSPRSKRRKLIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4S5</accession>
    <name>A0ABQ8V4S5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_559512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4474205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="257" mass="28034" checksum="2FE75B791200EC93" modified="2025-10-08" version="1">MPSRQQSPTSSATSGSSSKKAGHQRNPMACTNCRARKIKCDSNKRYPDHPCQRCVNRKLVCEYVAIAHTPSNDTRSRSGSFGSAVYPSPLLHDSNAKSHAISHSPHMQTRYSPLSTSLHSRSSSRSDPYATSFDAAQYPSSNSSYSDSSSGVESHLSSPLYGLYSSATNYGDSMMHTGSHMNQMPNIALSSTPQYGHFSSGMPGMVLNPLPDQNHYFNRDPSYADWNMASNASQGHYGAGECLCPGMQCTCGNRRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5L7</accession>
    <name>A0ABQ8V5L7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_869834</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="8">
        <location>
            <begin position="60"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4475818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="530" mass="60358" checksum="926EF3A2843E3C27" modified="2025-10-08" version="1">MTTLPEDTEPTDLPVTNDESQIFDWQTTTKGTLSDAFHIFTSDERSNEIPTQNAWNQNETRNQVEVYTDGSCINNGDDNATAGAGIFSKDDPTLTCAIRIPSTLKQTNQTGEIIGLKQAAEKAHLKDEVTFCSDSKTALDGLTTLREKWENIGYIGIENAREFQVTTARLRARKALSIMKKVKAHVGIEGNKEADKLANEGRMKPNEDRIDLTIPRHLCLSGAKLKCLNQSLVYQAIKQQKMEKPKHREKLNRRSTQQNIGMAKIGAIRLSGKTPSDKRIWGAMRHRDFSRQFRYFSWMTAHNGYMVGKFWDRTQEPWKGVCAFCKVEESMEHILTECRGPGMEEIWSLCEDLWRGKRTEWLRPSFGEILSCGLVELKDNDGNPKKGDSRLYRIIVSESAHLIWKLRNARVINGKGFPSAQEILNKWNNCINSRLQIDCLLANSRFGSKRLSQTIVEKTWYEVLQDKESLPDVWTKSTGVLDGEGENLLESRLDASPESHTQGVRSRRSCGTHFLQWAHFICIVLYFYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V660</accession>
    <name>A0ABQ8V660_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_600195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045564">
        <property type="entry name" value="DUF5910"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19287">
        <property type="entry name" value="DUF5910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045831376" evidence="1">
        <location>
            <begin position="24"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="226" mass="25277" checksum="82F9DBFDA9AA565F" modified="2025-10-08" version="1">MPVFCSIIYKFSLLLLMTRLGVGAFPVIPAESSNSTNVSIAARSGDNLLLGYVFVPEDKPLGDGAYLSPRPTTMFPTLDVPKLVSLSAVERCISPFLNTTFTLLQCSVEVGKEKLDEMILYYLAEQNLYYKPDEINSFLIKTLHGKFSSVIIFASFTIKGEKHIFMRIPPAFLERSPKSTGNQIYGKNTLGLKVHCVPVSSPKALRRMVAWEAWTEIKNWPLHVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6C2</accession>
    <name>A0ABQ8V6C2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_846370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14424">
        <property type="entry name" value="CUE_Cue1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045475326" description="CUE domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="205" mass="22211" checksum="A2FB8DDC5E4F1A50" modified="2025-10-08" version="1">MGEVVNVIVAFAVIVFIFRWATSSGPEGGAPSPADALGFRPKNVTQDMMDTVENMFPGIPRDNVRYDLLRTGSVERTTNKILERGFLDAPPPSYYTLYARATPGASSTVNADDVAVSSSRIKPKETLISRYNLQSKVNDVSEIVALNDAGEVGAGGGKAKWEDTAEKREASLKERKERMILAARQRMLAAQREKEENTGASTAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6J7</accession>
    <name>A0ABQ8V6J7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_845580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046851736" evidence="2">
        <location>
            <begin position="25"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="281" mass="30871" checksum="2A384DF54E3750D3" modified="2025-10-08" version="1">MQRLCFIPVLFIITLAVFTSTACAFPVFGPQARAESTSTKTSSPVASPTHPTITKLKAVFTNGGKKAASPSQFSSLKHHTIGYGFTLPKYVTEQGEVPLSKIKMKLEGITDKPQFQKDVFLVPTMTYAFTGWSLCMVYAASGGLQKLKQLSLIYEKDDLDRPPSYDPKKPPIEFFAAKVPIKGANHARTVAMHIPQIHVAKAKEIGLHTHCLKPNEKQSRLWGVAEWEKYGVEFWPAKLKADSDPGEPSVKSVTNPSTQTSGLAGNVSQRLPEHRHNVVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V725</accession>
    <name>A0ABQ8V725_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_844501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17259" checksum="F7B5E9C713680648" modified="2025-10-08" version="1">MSNVGERVKGVFNTVHGLGENVRATALGAVDTIAHDKEGEIKNDQIAQQGRLQTTRGLEQMSGRPRNVNTTADPSLANHPITSDYPQHHRDNEVYNDSQANAVRDPGSNAPSQHGYDTSGGVQPSGNAGYGTQRGGAGINNANVNPSYNSDNAQYDTGNPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V755</accession>
    <name>A0ABQ8V755_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD/NAD-P-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_844577</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="7"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4477951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="419" mass="46225" checksum="CC04DF343159A791" modified="2025-10-08" version="1">MSYSKDFTVAICGGGLCGLACAVALSRAGISVTVFEASSFSQEAGAGVGLGPNAVRALKGLGIFDAILARSDQPEPIPRLFGFVSAKDPHDSIFSYETKCDHPVALAIYRPAFLDAVVELLDPSIIRFGKRCTSINVSKDGKHVMHFADSTTHETDLIIGADGIRSVARRFVIGELAKDPLIYPNTAAYRGLVPTEDLRRAGVQTELTGRPLCFLGLDKHMICFPIKGATVINIVVFLSDYDKPPQSELPYPWVESVSQEELKEHCKDWGHDPKIILDHLKNPSKWSIHALDPLQNYVRDKVVLVGDASHAMLPHLGAGAGQGFEDVFVLVQLLTHPRTEKSNLSNVLARYNDVRPPRANDVLRASARAGRLYDSFRTPEQDKTRLQTKLSGIWEDVWSYDLHKDVTTSFETLHRLHVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7U2</accession>
    <name>A0ABQ8V7U2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_843996</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Cytoplasmic vesicle</location>
            <location evidence="9 10">COPI-coated vesicle membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Golgi apparatus membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="12">
        <location>
            <begin position="287"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="165"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4478929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="533" mass="57921" checksum="6903FF704BA01E35" modified="2025-10-08" version="1">MVVLAASICTKGGKGVISRQFREMSRIRIESLLASFPKLIPTNTQHTTVETSDVRFVYQPLEDLYILLITNKTSNILLDIDTLHLFARVVSDMCRTADEREILTKSFEILGAFDEIVSMGYREQVNLIQVRSVLEMESHEEKIQEIIARNKEAEAKEELKRRAKQLEMQRREQQRRTASSGGGSNYLGGGVTGYSPVPRYDAPDPTPSRITTSSLALSNARAPAFKGSGMKLGSKKTKQAELIDALGGDVLASPSLSTDVSTPPTPSVSSPAAPAFSERGSVPEIVAESVHMVVKEQISLSLLRDGGVQSMELKGDMNLLITDADLAHIKIGLSPPSTDFGNNLQFKQHPNVAKFAPGKERVVALKDPSRAFPVGQSLAVLKWRYNGTDESNVPLSINCWPSPSNDGTCEVSIEYELENENVSLYDVVISIPLPDGSYPTVTSHSGEWSLNPSSHSIAWTIPAISWNEDTKSGSLIFNVGGDDAGAFFPVDVSFVAKGSLAGVNVESVIKTSGERVDTFSVDSLLTVDEYLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8H3</accession>
    <name>A0ABQ8V8H3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase, TrpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_923757</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.970.10">
        <property type="entry name" value="Transferase, Pyrimidine Nucleoside Phosphorylase, Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285:SF2">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 3 N-terminal" evidence="4">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 3" evidence="3">
        <location>
            <begin position="89"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4475158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="38432" checksum="819205E262EE1B72" modified="2025-10-08" version="1">MGDYTSESFKPLLKRLVEKPEYFTSDDLRVALNHLFTPNTLLAEQIGAFLTALHLHRVERRPESLAAAAAILRERSLKAVVQDAENDFVVDIVGTGGDGHNLFNVSTAAAVVAAGAGARVIKHGSRASTSSSGSADLLQALDCLFVAPSPGIPMPIPRVPFTFILAPHYHPALAFLAPYRKALPFRTMFNILGPLINPAGPKGMVLGIAEPELGAPFAQSLRDGGVERALVVCGQERLDEISCAGLTWAWELKDGKISELTLQPALFGLDSHPLSSVAGGKPEENAATFKTLLTSGTDIPARLKPVLDFVCMNASALLVVAGVAADYKEGTRLALESITNGNAWAALETFRESGKQASSPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9P1</accession>
    <name>A0ABQ8V9P1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_923411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="584" mass="64931" checksum="920257AAA14E7D8C" modified="2025-10-08" version="1">MSLRRARSQTSLYSQARLTAQLSRRLEQVEELHGELSLKSQALGDAEKELDNLMNSESQRITFLENERKQVFAEKTAAEIKAERLQRRVDKLEAELQEVRKHTTSGSGLTSDSGFTRTSEAMLQQCDKEATIGRLSRTEDTLEADLKDQGTNNTGGNGDGIPVDAEGGSKGETTHRESSEVVSAHSPHTPSELDNQLQESQKNIRFDFRGPSLNAGEEGVCSAESTGEIEDIPVTAQNALVNFRSELPCYPEDALQSENALLWFRPAFEYLNHNLGEDYIYLISRWIELERNKNWAYSAKGISAKLRPKELSHWITNCRYDRPNNDPKFRQHNIARFGTNFVTWWNSLIRQISMVSGGNSDGRVRKEWGTLNTSGKNGWLSVIVCLKWWGLGLGDDREVYLYHIAPLIPGSVMHFSPLYLILGLFAVVHAAPLPATIDGKHLTLITRTDSSKPPFRIVVKLLGSPNSVKGDPKIPPAVNKRIVSHLNHGSSGTPTESQFRSKPLTVDEIKFFPGSVWDPATIPATGSFHFTWWDAQAQGFKWSDEAAGRELGVAHDESVEKGEWEVGVAVLSGPGGKSEGILLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9X6</accession>
    <name>A0ABQ8V9X6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c oxidase assembly protein PET191</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_713122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PET191 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018793">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_Pet191"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10203">
        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="70" mass="8015" checksum="E362553F5C25182E" modified="2025-10-08" version="1" fragment="single">MSSSCQGLLDALKDCLKHSDCVMKQGNLPSDCLKNHIEELPEECRSLRKATFECKRGMLDMRKRFRGNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA80</accession>
    <name>A0ABQ8VA80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_843036</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF447">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE_ISOMERASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06450)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="5">
        <location>
            <begin position="78"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4479872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="584" mass="65960" checksum="5EDA2303647C0AAA" modified="2025-10-08" version="1">MSWSFYAGTTTLVAVILYAYIRSNDKKLWSTPARALKVSPRRITEEDVEELKERMNRMEERRDAADTEASPKTGRRYIVVGGAGFLGGWIVIQLLQRGEHPKNIRVLDIRLPARRDLKYGIGKDVEYLVLDVSDRKAVKNAFKQPWPDASDASPSPSIPITIFHTAANIRFYERSASLLHNSTRVNVDGTQNIIDAALEIGASTLIYTSSGSVGVRASRFLLWPWEKEPNNFVQNLNDDDALLPKKHTQFFSNYAYSKYLAEKRVREADKSTSNSRPQGYRLRTGCIRPGNGIFGPGGDMLCGAYLVRQTNPTWISNIVSHFVYVENCAAAHLCYEQRLIEIERQHGVNSKDADMSSPNIPPRFPDIGGQSFTIADPGPPPTYGDVYLTLETLTNGQTFFPEISPTLMIFIAYIIEWYYLLRAFLLSFLLELSSVSSGVTNKPLLNLFSKLIKLTNFLLPPVNKDLVNLQPSLFNLTMVHLIFDDSRARMKPEQGGLGYQGRWNTAEGLWKTWDAHRKEVEIYEKERKDGVIRSDNQIRSDGAGVSFGFGMVRAQRGVSKVVEKVQRVEEKVQRVEANFEEVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAE5</accession>
    <name>A0ABQ8VAE5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_921893</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024789">
        <property type="entry name" value="APC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024790">
        <property type="entry name" value="APC4_long_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260">
        <property type="entry name" value="ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12896">
        <property type="entry name" value="ANAPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="6">
        <location>
            <begin position="26"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4 long" evidence="7">
        <location>
            <begin position="290"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4484101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="841" mass="93408" checksum="CB185F615AD2FE52" modified="2025-10-08" version="1">MNSNDFASLAAVQLPLSSRLLASACCPDKDLLVLVTRLGGHDRMSLWKMQGSKTWEIDVSTSSERIVGVAWSPDGQSIAVAHDPPSITLHSIQDGRSERVIHIPTSDVPIPQLTDIWWFHQEKPEKSPIPDIFRRNNIITGSAHSVLRTLPLLDQLRDESKQLTATDLFAFQGSQTTARRVASVPDVIELWPTLHPDPVSASINVPDTNRTAENGIMDEVDDANLDSILAVADRSGRLLCFLDGTYPLGSLKLGDSNTTIASLFKNPKSPVLLAHPIHDGVFTDLLPTHVSLSLLQGRKVRDFAKLSTTARELCWYALRVVEEMRAAWIGSDTNTGARDLGPKWIAAYETKQQDDYHVRPSGILDLTMLLVTDRPSEALGDYLGSGPQMSERGMQKWDSAVTEALVKLRDYSEKRLVPACQRLHLVLGEVRGWASLPTLYSSFEIPSEVVDQCLIMLKQAILLSSWLAAAARREHNRFREFMTWLRYETVLLGPSSETPNSTPLRHDILEVNQYLMSGLEKSVIDQWFMGPVPTFVPQDLGIPGYNLTVRAALQKAREYLDHRDPSETPITVPPDGFNDKPFESIDRNLFALIGAFASSCREVFDRPSAAATRAATISASSGSVIEQTTAASQRDNQTDLLIRDRITVDTLREDGYYVQYLVMHAPSASTSELRSFVNFVRQRYGHNSSHVEVAVHECCLRRGEEEDVVGVDVLALEFFDDETIVIVYRTDEGEAYIGTLSYRELEYTDFQPEGYVRFSRESLIESVSQGLIAGQLKSGYLPIRQSRGLKGCRSGAVSLAVNGRVGRRVACVLDSKGTTLETFDLEGDEGEEGDTTLDEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAR2</accession>
    <name>A0ABQ8VAR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_922784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4478922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="150" mass="16263" checksum="28C1B07563875E9D" modified="2025-10-08" version="1">MLREQARGPEPPPQMKLTLGVTDAERASSVSALSAPLSLDPPASLPLVGSSVALQILHLASKLASSSPNTATSVARLFCSTPLKVHDQRTIAIRYTTACAVGFTKSTQRIVSRWARISIRLRRIRSSLENRDDQQLRSVESRMGSSVPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBB1</accession>
    <name>A0ABQ8VBB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_868422</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="6">
        <location>
            <begin position="3"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="7">
        <location>
            <begin position="245"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4485149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="401" mass="44547" checksum="CBAB1148AC426CDB" modified="2025-10-08" version="1">MRFHVVGLGAVGTLIANHLRRSLPEGHSVSLIHKNVNRARQALWHNSIALEENGLPFVLKNFTHGTADVDVVSATAKLPNVTSDSRYIESLFVTLKAHQTLPAIRRIAGRLSPNSTIVLLQNGMGIYERLLQEVFVNPKQRPHFILASNTHGVYSRGLLDVVHTGRGEIRFGIVPDFEGRNFETALHDLSKPLEERRGDLADITQSEKLDPMFGRYRSLRNTVAALQLMEALNPTWLTMEEMQIAMRRKLAVNAVINPLTALMGCKNGEIFQTREAHSMLFRICQEASDVFKAEMVAEAKGFMNIADTEAGVDVLLDRIPEVLTRESLMQECLRVAKATKNNISSMLADIRSGASSGTEIDYINGRLIELGYAYNVPVPVNTAVVRLVRMRSKLVSGKVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCS4</accession>
    <name>A0ABQ8VCS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CFA20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_836154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="1">
        <location>
            <begin position="70"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4488591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="250" mass="28142" checksum="A660205101DFFE08" modified="2025-10-08" version="1">MFSAVVQSDQVSLFSSTGSNQLQLFSIHCDESLPSDAFIGLLNDRSSEPQPEGTVTLVSPHSSQPGFLLDQTVLHVQSPSLPNTYIQCPAQYGTELGLKHSWIHVQVRNMSREWSFEVGIADRVGRKGIIRFSTFQKQPRLKVPADSNGLPLLHLPFSFPSDSTQLTAWSTVNLHLPTFFPHFTNTNLIEHASDSIEDDFLHAHVLSPAGQYSHVCYIRIYSTCRLRRVWFSDGGPGQKLPWEFELYARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD93</accession>
    <name>A0ABQ8VD93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_954862</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF25">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127062" evidence="5">
        <location>
            <begin position="25"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="6">
        <location>
            <begin position="111"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="321" mass="33512" checksum="D20793C7C3C18E31" modified="2025-10-08" version="1">MLSHRYFVSILLSTGLLTSKLSLAAPLFGFGSSDNSASTTAVSNGTVTSDFLRPALFSRVAYCSSDAVQSFQCGSPCDALGSDIDVFQVGGNDGTIPMYFIAHDPSTNTIVVAHQGTDPNNLLSILNDAKFGLVDLNTTRFTAADGKGIQVHDGFQQTFERTADGVLAGVQNGLSTKNATNVLVTGHSLGAAVATLDAMFLKENLDPSVQLTTSVFGLPRVGDQAWADFVDSSLGNTLSHITNQNDPVPTVPPEFLGFVHPSNEFHITGVDSNGQATGIIACPGQDNENCSTGNDILDASVANHLGPYFDDISFGASACPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDC6</accession>
    <name>A0ABQ8VDC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045789142" evidence="1">
        <location>
            <begin position="25"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="23252" checksum="16DBBEE4D4D9A96E" modified="2025-10-08" version="1">MPAPHSPTIWTISHILVFFQRAIAEFDLPGKIIPTHSHPGGITVAIRIIPLIADLQAIRKVAGFLSHAAGLFCSFCNCHRDDIEDLDYNSWQMRDGATVHAQAAEWKNLVTVTAKETLARQTGVWWTPMHDFSYWNPTKHVVLGFMHNFLEGVLAYQLRALWGIGRTKEIVKKIAQILDDESNSSIDTEEYIQESQDLENEAEQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDH4</accession>
    <name>A0ABQ8VDH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_883609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132:SF1">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="542" mass="62003" checksum="126A177CB7451FF3" modified="2025-10-08" version="1">MSSLSSVVSDLVRASMGSSVAPTVTDEELDKHVRELLIRDAKKRAERYGQQGIRAYLASGLSDSNAPKANKRFLSSVIRSTDEHNKTILRAQALSAEEIKRERREQEMKERRARAEEAVRAEKLRRSGSSASRRRAGDSEAWDRWDGTTSVRKRKRRNWETWTGEEDEEERHRSRRRTSHRSSSRSLNNNKESHSNRRSSRRSRSRDDRASSSKIQKRRSRSPRNSHHKSSGETHSSRRNKEKESYRRDSRSVSPSSSRESDREAHRPRPSKHKKDTKDESKPKRRYALSSSDEEDVPRRRSRSLTVQSDLGSAYAYSSNSRYHSPEPPVPSSSSSTLNREFELRKKLQSKYPAQDASHSREEERVKEDSDITESSQRNSRSRHSRSPDPKLKRRKASRSSQMSISRSPTPGPEQPGPALPSKMDKYFDESYDPRLDVAPLSAAPKVPATGLIDSAEFEGWDTMLDLIRIRREDKAEKKRLERMGLSKDEVRKTMFGDPNAVGTASGGSVSDRWAGEGVSAMNIQYNKRGSVREWDMGKETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDV3</accession>
    <name>A0ABQ8VDV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_382486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="32874" checksum="D7D075E47A4BE292" modified="2025-10-08" version="1">MILVDCRSKYSWDTATSLHIHLESTRGMNHLPTIYQNSDIKFRQQASLKEKFDDGYQKCLLRFSIQDELQPLMSLKSSKEYAQAFYDVVQCHHWGWKYPRILHRDISIGNIMVREKDRQKYGVLIDWDLVIWFDERKEGSTSKFRTGTKPYMAHEQHSSDWQGPHRFRHDLESVFYVILLLVSLYSSPTEKVRFPSTGDHRYEEWHEQGDCFLEGRKLVIVHAGNWQPFPEPFFSGFTLWLITLQDFFFRGFIDLGNHRHAAKRPLKPGRRLRKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDZ9</accession>
    <name>A0ABQ8VDZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_766716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="23"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="197" mass="21734" checksum="0EA61842D4E52065" modified="2025-10-08" version="1" fragment="single">DNYEKKYPSDPLGEEVKENARVWKVYLDEAEHYDDEMLGGFKDTIDSLLVFAALFSGVVTTFLTVTITAFQPNYSQITATLLVEQVQLLRAAGNLTAINAIPSTTLNPDDASPGSNDIWINGLFFASLSLAVATALLSVLVKQWLQAYSSISFGNAKEKALIRQYRIAGFEKWQVPEIIGTLPLILHASLALFFVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE46</accession>
    <name>A0ABQ8VE46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zn(2)-Cys(6) binuclear cluster domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_838977</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14725">
        <property type="entry name" value="ZIP_Gal4-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4485186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="642" mass="70068" checksum="CFF9C8437D451046" modified="2025-10-08" version="1">MSSERVASSSSSPYSLQRGKACSNCRKRKIKCDGLRPTCTQCLRSARPGDACEYADSGRTRTQMLEDNISRLEARIRELEEPDDENAVRLHLPYNFSSQSTPALMVPPQTGSSIRGSALSSPTNTQRNSNSPSIASSSGHGSTYSTFQEEPPSDVVHQLLSTFLPHALDMGFFLNVSRFRNSALLPLPLGHYSRPCAGLLSTVYLLGLHLSGDLNNQESVYLARALAHTANILSSTHPQRIIHAIQAETLLSVYFFRTGRILEGKYHMSAAVSLTLGTQLHKIRALPVGSGHPSVSPLQQISVAGPLLTPPIDQIEEGERINAFWIVYTLSNCWGVAVGTLSSAVFESHGSTIDTPWPLDMTDYEQVMLNASRASRTYGADFGSLLTSQELLPAEHYSVMTVQNFLRQVPSSSVKEFSTMAMFAKASILLDKSANIASLYRSDMNADEASRFGATFSSLNNLIDNFQSSLGFLPLNQHASSSYDFGTILTTHTLAYTATIQLHSVFINNNPHSRRKALSAARACVAILRQVDMSVMSHINAVLGSCWTTVCQVFIDEIERLRRTSTTTAGVGIAGGSRLHSRSSRTESWGISEGGLDSISDREEVQLKGMLEKVFATMAVFSIESPLIGYQLATVQEAFQSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE61</accession>
    <name>A0ABQ8VE61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_378676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="572"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="77"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4491055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="629" mass="71205" checksum="FF7DA5714299CCBC" modified="2025-10-08" version="1">MSMFTNAHQFSIRGGIYNNVARDQINLYESPQTVSGNSALDILSEFIKDVGAVHDSAQRYPPPKCHPETRKGIQTAILEWIHSQQNGRPVFWIHGPAGVGKSAVAQTIAELAEIRGSLGASFFFSRSHGERGRAEYLFPTIAYQLAVRIGEFNKVVTQTLRKNPGVLRSSLDIQFEELFLNTCGSAMKLGGKWMHQPRVIIIDGLDECTETVFQQHIILLIASVLKDKLPFRFLIFSRPEPQIREAFQAHVPQSLLRQTSLDKDSWDARQDMKRFLESGFFNIRTQARTSHIHFPPLWPGREVIDELIEKACGQFVYATTVLKFVDEEHSHPMEQLSIVLGLKTAARGNSPFKELDVLYHHILFSYPDHNKVTMILGASIHLSSLSGLRRWNNHPCGPTIEVIEALLGLHTGEVLLVLRGMHSVLNIDGNHIQILHASFRDYLCHKSRSGQFYIRDSTFIAHLFLSFSGVKIIVTEPRRMSVLVNDFEPHRDYMPFIISRSSNVLLLSMFIFTPLLNTMLLGFIPLGIISQFLHWSIALRFSFSFLAAINLTEFLNDTMEYISTGLDQTHTGILNASFGNIVKFVVGIAVLFQGKIFIVQHMGYAWIHLGKHAINFRLVLPCRFVITCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEP3</accession>
    <name>A0ABQ8VEP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UAA transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_833905</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF4">
        <property type="entry name" value="NUCLEOTIDE SUGAR TRANSPORTER SLC35B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047362392" evidence="8">
        <location>
            <begin position="19"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4491737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="398" mass="43273" checksum="C9E45FE20AA1EFBB" modified="2025-10-08" version="1">MLTEWLTTISFVFGGCCSNAVTLEQLTSQFPRAGSLITFCQFAIISIQGIRRHVTWSSYGPRLKPRRIPLMPYLIQVVLFYLVSLLNNAAFAYRIPMAVHIIFRSGGLVISMILGWIFAEKTYTTAQVLSVFIVTLGVIFTTLSASEPSSNAMIGSSTQVYLTGIGILTLALVFSGFLGLVQDYTYTKYGRPPNSSDKSFAAPTWQESMFYLHFLALPMFVTVRKDLMSQFYALSRGPLASYTIAVPPSISATILPSLSLPPPSATPLYPKSSSFLSFTNVGTSSTSSLVDPDALLLRLQLPAACFPLLLNTVTQLLCAVGVHRLTTQVSSLTVTLILVVRKAVSLILSIIVGWGRKANNPENVNMNMMWSGAALVLLGTIGYSLATNATTSTKKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF27</accession>
    <name>A0ABQ8VF27_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nuclear proteasome inhibitor UBLCP1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_833436</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011943">
        <property type="entry name" value="HAD-SF_hydro_IIID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051658">
        <property type="entry name" value="UBLCP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02245">
        <property type="entry name" value="HAD_IIID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="13">
        <location>
            <begin position="49"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="14">
        <location>
            <begin position="182"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4491862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="42396" checksum="288FF9CE6A9439C6" modified="2025-10-08" version="1">MEKTLHSPTSMPSSSTHEETKSTPIASEAGVTQSTTEFSQATQSPERWVTLQLTWAGKPFSLDIADSDRVLDLKTALHDLTRVPPERQKILGLVKGKLPPDQGRISDLKLTTGKKFTLLGTPEGDEIKDPAQLGNLPDVVNDLDIDFTKDPNAVKRYKHDQRNIRKVKEMTDKLSVNIIHPLREGKKLLVLDIDYTILDTKPLTSGSLPPAECARPKLHEFLEAIYPYYDICIWSQTSWIWLETKLVELGMIGANRNYQISFVLDKTCMFTVFTERDGQEWQHSVKALQIIWNHFPQFNATNTVHVDDLGRNFALNPQCGLKIHAFKNAHTPEAQADRELDKLARYMVHIAPLSDLRSLTHTNWKTVLKSLPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFR6</accession>
    <name>A0ABQ8VFR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046538356" description="Hydrophobin" evidence="1">
        <location>
            <begin position="25"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="24308" checksum="A16A642D67B20A98" modified="2025-10-08" version="1">MSFINKAITFASIFLVAVEASVLAQRQTSCATLLESCADSACCDGFTCASLPILGSVCSIALPTGTSTVSTVSSSTGTGSTGLPSSICAASGEPCVSLAGDNSERWGSHAAPGYLPIVESKFRVTLPSKVPTRYIYIQKVSVEKVNTNTKVSQLQTFFESHCTCILLPPVTTFWFSMGVVSRAVVLNETVHLPHDRMVFDARVSSAILYAATASVCLSLVLAKGNHDSLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFT2</accession>
    <name>A0ABQ8VFT2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_831866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="383" mass="42475" checksum="E854AC7695496737" modified="2025-10-08" version="1">MTQSLFQPIQIGAVTLRNRVLMSALTRNRALPTNVPNKLMVEYYRQRAESAGLIVSEGILICQQGTEWPHAPGIWNKQQINGWKNITDAIHEAGSQCFAQIWHLGRASHPDAPEQIASGQPVYAPSAIPARGGKFRFLPGVPGYVTPTEIDNPMKLVALHKQAAINAKEAGFDGIEVHGAGGYLIHQFLDSGSNIRTDSWGGSFENRSRFGLEVLRVVIDVWGANRVGIKLDPTGGYNDMGMPLEETLETYNYFIAQVDQLGPAYIAIQRYSEFNDPIIEGKRRAVQHDVVAAYSHIIKKSTLLSNGNFTPEEAAQYVSEGKISGVFWGRLWISHPDLAKRIRYGKPVDTPVDMQNVYGNMDGMTLDDQRVGYTDYPFAENEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG91</accession>
    <name>A0ABQ8VG91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="377" mass="42361" checksum="FB0661E9A62F9973" modified="2025-10-08" version="1">MDSDSISQDDETAFAAEDSESLDAFHPAASRFATSISHISRTVIHIFQSPDMLYVLTMERRITRYFLLHGLFVNFLLAGKILSSTYNAITMILGADLGDVIAIALLMICARVISRHFLQDWKADVGISDLLFSRVQKTIRFLVVLSILSFAFATWRLLSFLELTLDLCFWVLVCIAIMILHLPVLILDILLWFIVSYFMGSVISCNDIPYLDTVILDVGVCDLDYTTATPYVDQNGIGTHSFGPGDQKRVATRGWRRKHTCTSELKYMDPEQERTWKAMEALVIMMLINGPLPQEDGLRAIPTSNMVASVKNEEHGEDSLSSRTVSQERRLCAISTMGMVTSGEDEEGVLLELRLDVSLRFLAHFAGRSYCQYCLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGH1</accession>
    <name>A0ABQ8VGH1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Polyadenylation factor subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_896156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045245">
        <property type="entry name" value="Pfs2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="217"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="259"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="301"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="419"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="565"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4488648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="633" mass="68494" checksum="C6DFD50931582E1D" modified="2025-10-08" version="1">MSKAELQPLPILLPTKVLPQEHSIPHIEWTPKKYLDPPQPPPVDDARAQEQELAHARQFMDGKLVKKTRPRRTVDFNGGMGRWAMLRKLRPNPLYTHQMRPCPPSIINLLPPKAYPENASTSLCTKFVHTSTNKIRCPVNVVTWTPEGRRILTGSTSGEFTLWNGLTFNFETILQAHDTAVCTLAFTHSGAYLASADKTGVIKYFEPNMNNLTAWQGSNSREAIRGISFSPDDRRFATASDDSSVRIWSFQESRVESVLTGHGWDVKCVQWHPSKGLLVSGSKDNQIKFWDPRTGTVLSTLHQHKNTIQALAWSPNGNLVASASRDQTVRVFDIRAMKEYRVLKGHKKEVCSLAWHPVHPILVSGGSEGSIIHWDLSSEESSSSTPFIPPPSAKSKLSDLPAHLTLPPTPTALPRATLAEAHDSNVWSLAFHPLGHLLVSASNDHTTRFWSRERPGDSDAVFSAFGEKPPAAVDGADGGWEDEDMAVPGFGGAGTAGGWDDGYEGGINDNGGTGASYSNGNLSNQNGYDSGDRGFAGGDDDYSIPGIGDSGFGSASGTNSIRVNGPLPPQEEAIYGSSTGAGPASDEWYSGGGERERSGGGDRGYDTWGRGGGARDGGGGGGRQRWGGRRTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGK9</accession>
    <name>A0ABQ8VGK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial adapter protein MCP1 transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_764310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039960">
        <property type="entry name" value="MCP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012472">
        <property type="entry name" value="MCP1_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409">
        <property type="entry name" value="MDM10-COMPLEMENTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409:SF1">
        <property type="entry name" value="MITOCHONDRIAL ADAPTER PROTEIN MCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07950">
        <property type="entry name" value="MCP1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial adapter protein MCP1 transmembrane" evidence="2">
        <location>
            <begin position="113"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="251" mass="27500" checksum="167332D5B44E354A" modified="2025-10-08" version="1">MTDASSPRSLSFRQRLLPLITLSSHVSAPFITTFLLIHLSAPALANVGGSSLSSQVMLLGREYYQTSLAEPYLVLGPLAVHALSGVIRRALIIIRGALPTTTLSFTAYTVLLLLPIHIGIHRILPQTTTPPVLSLGPSELDYSFVQYGLQRWPARTWAMYAVLVGAAITHAVEGSRVLMGNLGLESALKKPSSNSVVPMNSKVRRKILAAALALPILSGLYVVYKERLYLFADMGRRLEGVYRLSWIYNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHD8</accession>
    <name>A0ABQ8VHD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCA7, zinc-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_712878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013243">
        <property type="entry name" value="SCA7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037804">
        <property type="entry name" value="SGF73"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805:SF1">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08313">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51505">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCA7" evidence="2">
        <location>
            <begin position="128"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="338" mass="36630" checksum="46475342FCFB208C" modified="2025-10-08" version="1" fragment="single">MPLKLKGASTPPTEPFSWDALPSPSPPPSEISAVTEPTTVWLPARDMKLFGARPLSSTSEIGVMRCKDCDKPVLKSAVSEHAANCAQIRNIAMIAQAKKRKASPSSASLPGEPSSKKAKKSALPKITKGRMKGPVDFDKQCGVINDKGLPCSRSLTCKSHAMGAKRAVQGRSRPYDDLLLDWQREHNPNFVEPVKRETKKEKKEKKDREKAEKKRAIEEAAVRLGYDPSSKEGRKAGAAATGHTITTSSKHGSSKRQTAAAAASSAHTLDDADNENYDDLDSEAEVDDLAGAVRQARTLGVIAQPLAVPVDAGSWFVERRERFRLAYHMIGVALNPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHL3</accession>
    <name>A0ABQ8VHL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS0</name>
        <name evidence="10" type="ORF">C8R41DRAFT_763527</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03015">
        <property type="entry name" value="Ribosomal_S2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032281">
        <property type="entry name" value="Ribosomal_uS2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027498">
        <property type="entry name" value="Ribosomal_uS2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_uS2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16122">
        <property type="entry name" value="40S_SA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS2 C-terminal" evidence="9">
        <location>
            <begin position="204"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="262"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4494444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="296" mass="31946" checksum="B98DDA01A2ABB0A9" modified="2025-10-08" version="1">MASKLPSVLSATEEEIQLLLAAQCHIGMKNCDKQMESYVWKRRADGIHILNIGKTWEKLVLAARIIAAVENPDDVCVISARPYGHRAVLKFAANTGAQAIAGRFTPGSFTNYITRSFKEPRLIVVTDPRVDHQAIREAAYVNIPVIALCDTDAPMKFVDVAIPTNNKAKHSIGLIWWLLAREVLRLRGTIPRTSDGWNVMVDMFFYRDPEEVEKQQQEEAAAKLAAQAGEEPAAGLTEWDVASGPAAGAINPALVSQEGATLDWSADATAGPTDWAAEPSGAGWGADAPAGGSGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHM4</accession>
    <name>A0ABQ8VHM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="438" mass="47625" checksum="A4A133A9EA603D79" modified="2025-10-08" version="1">MDYGSHCPADHDDGASTSKLQQWSQGPAANAKLSSGGKRRPSLVFVPSAQSDLYAQEAPLDHCLWQVQYYSETLEPSSNVSLLAQTEQEQDDIFYATFPQARGLHWSPQVLPANEYSGYFGGTAFSLSRNGPGHDYRSSGLPEHDPPCTPSVRYSPGSLHIEAGCTSSCIVSSGSMSTIDSCGNDESVARLECDSSQLISLSPERDDLGDVPSSPKIEPFDVPLPKSPLQLDIEDVNTATFSCTHEPLMNFLTPPFTEPEASSPEKSPSHIEDILKMNTTSSPTGTWPSVRVRSIQNTPESDSPTSSNIDRRDTPEPFTSTTTPPLATSSPRAPKPQLDTHFPPESSGLMRLSPLPMNRRPIEKKKAQTLACNFCRIRKVRELATIWVLVVETVIQIACGPPLAGTVEKTCKSAGEYSVYRWSSCDIADVLFSVSAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI06</accession>
    <name>A0ABQ8VI06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_404611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4488629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="630" mass="68995" checksum="4DC01000403A0626" modified="2025-10-08" version="1">MVSKIRSAERVNVLIVGAGPVGLVSALLLLRDGLSVRVIAKETKPRTGCRGPGIQPRTLELYKFLGVLDDILAGSGPHQSIHQYTSPDNGEPPVILWDQSKEKVEEKVDKPYLSPRIIAQVDHEAILRACLLRDYGCQVEFGTELISYEQGSDTVEATLLKISTHKTETETTQFDWLIGADGAHSVVRKHLGCSFLGESIKKAGGMLLADIHLLNGWGDDHIKSWGALIEKSLMIRPYRSASSAQPKSDTRVQVMITDKDLDDTIGKLKLNGVVGDGNTVDRRDMLVDMIYELSGRRDLVFGDLIGIGVWRPNVRMVDNFGKGKVWIAGDASHVHSPTGGQGLNSGVQDAFNLCWKLSLVHKGLNKSTSNELMTSYTEERMRVVKAMLNVTTRLLRQTFGVNEEKSVKIEVGVAQTIGTTTISADSPDKKQPSGINVIRGFELRMFGINYRGSSIVLDEVAPPAEVLDPYKMSPEEPVRGGDRAPEAPDLKILHRNSSGGTTSLFEIFDTTKHTALVFFQSPLAIQEFSRALDNYPNGTMRIVVIHPQGSTERVLIDGKQEGDVVEVLDTKGHAYGSYLRGVDFHAVVASEGAVSQETRGVVIVVRPDGHVGAIVKDVAGVDRYRRKVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIF0</accession>
    <name>A0ABQ8VIF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_902310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="556" mass="63757" checksum="EC1246CBBDF1613B" modified="2025-10-08" version="1">MNKGIEVQPRLQSLLTSNEPPFDSDVLTITEMLQERLAHIFELEQQLVKLRTEAHVYESLLSGMRRLPPELLTEIFVHYTAPIWQRDYRLSIYSCYPRANAPHQSSPMVLSHVCRKWRLVALSTPLLWTAISIPHRTPLGCISYASLVQRCLTNSRVSPLYITLSVLSSAQMQYRSPAAKGLRNAGALETLDKFMPEIYRWRYLHFDILTSQTMLLERNFPPIPTTGAPNMYKIFFRAFSADLNSPEVLWALELIRASPNLHKITFLAPILNLEATSWIHLQYFESRRGMRLSDLFSIFIGCPALRSCIACFELEEEGPSLPSFGESDPLIQSSYLHTLQLTHLRHAELLAILQWLTLPSLTDLTLAGHHVSDTWPGELFQSFLVRSACKLNTLSLSRFSYSDTNIMDHLRLPNIHDTLEHLELDKWKTPISPELLNFLTFRFTSDSPVNFPVLPKLIDVTFAIHAIVQAVRLREFFLSRWYERSRNHAPFPVAALQRMSIVLLVPYLPNATVSGEQIRRVFSRIEEAVDIDLETCVVDGGTDYPEIEKLGDWDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIN0</accession>
    <name>A0ABQ8VIN0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="498" mass="54547" checksum="1EF9513A5AE9D3AD" modified="2025-10-08" version="1">MKGSWDGGDQGILNEGRGDNWNRLGFTYNTTPTAAYTYAPAYERFGKQISAIHFIGPHKPWKSIQYRAPFLSQQPHVDLMRPQPPPRLHEQREDKTPPPRPSSPPKLLWNPAIEPPPNTAPPPSAFPSDTYFQNIWDQALSKQHYRTHPHAHYTISLTPDSGAFFEPPPPSHIPERIQDRTVYKFDEVFSPPSKPNPPPPKGLPAMLRLGIQCRVFSDMLPDFSRDGDDEDNTDSDDDKPVVSRLADSDNKTSVSGSSSRTRSRREMREQAIQVSILVDSPKVFNAPKLSQDQKIGSPRRSSLMLQTGNSRRPQWTTSSVPSALPPIVSVGRGGSPESRVNPTGAGIGSGGNDASNSRTSPTLDPLSPREYGFKESPTTVRPPARSSSSSTITPFHANMVAMAGVNQRSFGSPQGPNAPPLGPLRNTSNDSMITSPPLSAGPVSPHKGQPITSVASSRKTGRVFDPARGVELFKCGSEEVLARFLKMSSWEEESSPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJI2</accession>
    <name>A0ABQ8VJI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VHS" evidence="1">
        <location>
            <begin position="72"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="301" mass="33528" checksum="0F2699347C4D942F" modified="2025-10-08" version="1">MSQCVEQLSGGGENNVYNDSELVGMSPFLQLCLSYDSGNFIDYHIVMTAKIIDQKLTPKNDQLTLDLCNEWLSHNEPNAQFNALSHADALSKNCGVTVNREIASRAFTAGLEKLINSPATHHKVERYALSSISRWTRKWADAEGLPTMKDRFNTLEADYYGKGSNFLSFKDIFQSKGYELWDNIRLARAFVPPNTNPRAPDGLSYDDPSGTAGKSYFISAVEKYWPARTPDNQDVLLVLNKDPVKLEILHDVAMGTKGGMDGNHVLPLLRIIEHEKLTFGVSPLIGMSLLRGLLARTIVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKB4</accession>
    <name>A0ABQ8VKB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="785" mass="86081" checksum="9A93B12E6902A71A" modified="2025-10-08" version="1">MSIHTSPVHALVPRASTLALTSDAAIEYVLADIPFFCVGLVAFAFFAFMLFMKRVTLLSIYLYSTALFSFVAAVIDLAQLLVRGSVKVNMNTGITSGVTALINTREVGLSIAIGLRFLFFWAFVAERPRGEPPPTIDLSDPRVYVYHAQNSHSAEWERWGYLGIFLKWLILASVISIPILQIIWRIAARHFGVVYMVESTIEILISALLLLKMILNVFLSPVSPWWKPLRFYIAPLIALLINLGIGIGELVYFLFSDTALGRFLQAFEVYLMFIFLMLVAFYKVPVRPIRPSVSTSYMVDKKPQNTQSVAEAAAVVEEPVADNDPQTRLSMVSRVTSWIIPSRRQSNVERQNQQNTEDVEAALTLPSSQPIQQPKQSLSVRQSLQEARDPARQSVWVPPQPDPVDDSDLFVRPIPTPTLAISSSVLLPERDQMESGSENRTSTGVSLRYYGVGHDSLMSYPNPSFMVNDESSLKSSGTDSPIYGLDGIVKQQKNRNSAGSSLRPPRRPSVSSFDELIQQQAELDRSIAALRLFSPPTSFAEAENPSAGIPDGTSLSTTNNRTVSTLTSSSVRSEFSLSIFPDPPIADFPLRASFSTMRANRTKRQSRRDLPTSFDNVSLDVPSLPDTPMRLAPGRSFGSNATQYDVTSFIGHLTRPSVTEGLAQSEAANPASLTNVSEEVQTDTKSDTPVAEDLTLTKETSYPQLRPFFLGNVTTSPAVSSPLAEGARGPSTISVGPRKPVRGRLALPSNPRPVISAPMQSSLDQAPGAFESPRPPPSFSTSSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMJ4</accession>
    <name>A0ABQ8VMJ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_829885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="6">
        <location>
            <begin position="109"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="305" mass="34715" checksum="3299050F940A8648" modified="2025-10-08" version="1">MPSDLDGQIEQLKRCEPISEEQVKRLCFKAREILIEEGNVQVIDSPVTICGDIHGQFFDLMELFKVGGFCPDTNYLFMGDFVDRGYYSVETFLLLLALKVRYPERITLIRGNHESRQITQVYGFYDECQRKYGSSNVWRWCCEVFDYLALGAVVDGRVFCVHGGLSPNLQTIDQIRSIDRKQEVPHDGPMCDLLWSDPDDIPGWGLSPRGAGFLFGADITKAFAHHNAIDLIARAHQLAMEGFKMMFDNTIVTVWSAPNYCYRCGNVASILHLDEHLSQEYKVFSHAPVDVRSVPAKRPPADYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMR1</accession>
    <name>A0ABQ8VMR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_821540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="3 7"/>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF61">
        <property type="entry name" value="ALPHA-GALACTOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045829285" description="Alpha-galactosidase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="9">
        <location>
            <begin position="333"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4497551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="436" mass="48049" checksum="1FF70D921949907C" modified="2025-10-08" version="1">MLGTTCLLGLGSAILYTTSFSLTPVNALRNGVGRLPALGYNTWNAYGCNIDEDLVLEAAQLMVSLGLQTAGYEYVNIDDCYAEKNRSENGDIVANSVRFARGMNNLTDQIHALGFKTGIYSDSGWFTCGGYPGSFQNELRDARTFQDWGFDYLKFDNCAIPFDDVICEGMIGKFTRMADALAHLSKKSGKPPFLFSLCQWGWEQVWLWGSTLGHSWRVTGDISPNWDSLTLIINFNSFITQATDFHGHNDMDMLQLGNGGLTFDEAKSHFTAWALMKSPLLIGTNLSAITPEILEILTNTEILAINQDPVVGKSISPFRWGVNPDWTSNSSFPAQYYSGPSENGTVFMLLNTLNGTSDMFFNLTESPWIRAGREYSVRDLWTHTENGTAIRNFTATNVPPHGVVALLLKDAGDEPEGIFPPCAVPSCSFENGTIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNB3</accession>
    <name>A0ABQ8VNB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="441" mass="47261" checksum="00D8E7215DD2168E" modified="2025-10-08" version="1">MFEEICLTCGKHLSDDGRVYCSDECQNIDTASPSISSASSALSSPRFGYAIGGEVPALVSSALGKALRGYHTRDHHSISSSASSTSCSVLTDEEDEDSHFVSGSEGAYQDEYAEGKSKSSGLYPVLRAPLSYARRPSGTNNVHAAPHVLGRVPTSASTSGHVYSAPRSAPIHSHSQLSTDDETYSDFGSRSRDELGSYTSLTTPDEDQNRSTITKAKRTRNRASLPAYFSLLQVSSDTQPRVSLSVSNSSGHSVTRPSPPTPKLTIAGMPVHPFTAPPAAVMQATPRGRRRDLEASRSTRVSSNDSSSSRSRAENPFAPPATASEAFRSQLSSKGSKSSMEKILDWTAVSGLSRGRATIRRNSSPPPKMVLTAETEQFNIVSRGRKADSTSRLRSRGRVMVSELDGVTVNKEAPGFGHGRSGLLHREQAISQRFMSGKPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VND3</accession>
    <name>A0ABQ8VND3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_894319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="585"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="68896" checksum="AB12C5272DE33474" modified="2025-10-08" version="1">MYSRQHLGSPPPQSQFRRPWSPDPYDPYPSVNNNSRNVNQDPYSFQENTINDLHQDYSRRPIQPSQLYQQHREPSDASIEALDLADYARTLRPHGNWQQEPEDDALDSLHPPSLLSRSGTLSSSSHPSVRSPTHRPFLLPPSSSSRQPPYPRSHPRTSYRSHNYPYLATDEPEIVTSPAQSEVDISQFPPWSRRWYNPNYSHKPLSPPDIYSPLPISTFDPKRKSGDVFDPDHTLRRGSYSKPFDSDPQYSSSYGNDSSRDLLPWSSDPPEYGPTINDSIKAERIRMLEREFGPNAKSNKSSSRNDDFLDDNGKPLVGTVDSKGNLVTQGRNKRIATRVLQIVFAAAAGIPSIYAAILIRPNPAAPPSGSIAAYVLYIFSVITLLALLFLFMIYPCCIRRKKGHSVPGDRANPLANGMMVLPVQSLPGGKTHKKAKGKKGRKGQGANAGDVQVNLIVDPNIFGGHRNDEEEEGEGDEEDENGDGGDGDTWDWEGSSIPGGWSHSSNGGHAARKKKKHRRAKRRSVFVGLAMEEEWKKARSFAKKIMAFDIFGVVLWGTVFVVIMMGKRCPIGRYDGWCNAYNVSSAAACLLCFLFGLSVFFDIKDLHTSNVSPRTRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNE4</accession>
    <name>A0ABQ8VNE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial</fullName>
            <shortName evidence="7">Glu-AdT subunit B</shortName>
            <ecNumber evidence="7">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_760405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004012">
        <property type="entry name" value="PRK05477.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asn/Gln amidotransferase" evidence="8">
        <location>
            <begin position="353"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="511" mass="57268" checksum="B2C67169182834D2" modified="2025-10-08" version="1">MSRWLVDGWQVIIGIETHVQIKSSQKLFSRAPTSLLNDAPNTRYNTFDAALPGTLPRLNRKCLDLALRAAFALGCSVNKRSSFDRKHYFYFDQPTGYQITQHYSPFAVNGQYTSPKIGLPIRIKQIQLEQDTAKSITNARTRTALIDLNRAGAGLLEIVTEPDFRTAGQAAEYVRSLQELLRAVGVSDGNMEAGSLRCDVNVSINRPGEPPGTRTEVKNINSLKFMVAAIEYEIQRQKTILETLGPKQKVPQETRGFNSETWKTFRLRSKEDAPDYRYMPDPNLGVLVLSEQHIEAVRREMPPLPDATRLRLIQTYSSSGVTERNIDVLMNLDAVRDIAYDGVVEDTVVGAVAYFELCSQGRDPKFVMDWIIQNFLGQLFALGKPFSTEYIPVAQMGDLLDLITTKQITRPSAKLLLKHMLISPSDIPVKQLAEKMDVLSSVDELSNSSSHDDPLRDVCIRAMDALPSEIAAIQAGNENVMNKVIGWIMRQTKGKVEVIRAKDILKQLLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNH6</accession>
    <name>A0ABQ8VNH6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Snf7-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_174053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF96">
        <property type="entry name" value="BCDNA.GH08385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25880">
        <property type="entry name" value="WHD_CHMP7_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="491" mass="54013" checksum="FAB7027CF8688126" modified="2025-10-08" version="1">MTSRTPTPYSSPYKSMSATISTPPFMSGSRYRLQSLYSDFSEQKRSNPASYQANVDWWRRTLETYVSEGFHGSNRLVLKAGQQLVDNFRVEGVGKPICFHAVLTELSSPPPSSATAVLPTLLPLTTFISLATSLYSSKSRSYLTVIPSFFLSYVVAKPLWWALEQVGVVGEDSLASSVSSTFSSFGSATSKTNTQWYGDYVLLHLVERAGNAILESQRLKNTGPSDALYTFDSFRTEFAECVIGSDSKDKMTMSELDMKVILRYLERDKGVVMVENGVVKFIEDDAEAEISGVDRGILELKTAVANLHAQIEGLQKKIDVCAQKAGEALKLKRKSIALSYLRSKKQLDDLLIKRLGALSNLEGTLIQVEGAAGDIEILNSYRASTATLRSILSHPSLNRDSIEQTMEAMAEANADAKEIDEAVRIGGDVAIGVTDFDDAELEEELHRLIIESGEEKQDELREMKLGSLPAAPLHDVCETSRTTPEWEAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNX0</accession>
    <name>A0ABQ8VNX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_158619</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07542">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047821">
        <property type="entry name" value="P5B-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="666"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="702"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1206"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1230"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1270"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1322"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1352"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1393"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="277"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="523"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="36"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4498096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1448" mass="161037" checksum="ED085F22750A9C07" modified="2025-10-08" version="1">MTPVAGSSGPQGAHDYTEGASPIDINNVLAHSRRSSELSVYNDDEGTMFSGPGHSVNPSSVTRMSNIDPARRSWSRSRRKSHDSGVSGRLSIERRQSQDSQHSQLSRQSSQEEDVEVNSQRHTVRGRRRRSPSPSARPSVLGNWASLFGKSQATQDGRRLSFSSRRSSASLSRQSSRSDAGSEYAVETDDEERWGYSSGEENSDEELSGRDDASISRSMDYDSEPPSPTMNQGLPLLSSDPIFGGESRIEMEFSFTEMEPPPPGPPSRQQIHIEEDDSTIRLVGYEIILWRQWLWRASCILTFGILGLLGNWFPRLWLGFVTHEKAFIDIKQGFVVVESSNRDVMLISLHKLEYPFPITTVFSSSFDQSSSGSSLKSTETQTYNEETKMLRSLIIMNYRYSRFALDPRNGLFYVMRNWRDSSWASSSILQSGLQEHIRRQRARLFDRNEINIEVKSTTALLINEVIHPFYVFQVASVILWSLDNYYYYAFCIFAISIGSIATTLVETKKTIARMREMSKFNCKVNVMVDGTWAELDSTDLVPGDLVNLSSSQLTVIPADMFLLTGDAILNESMLTGESIPVSKVPVKDEDLLKWRDGKMENAKSFIYGGTKVIRIRTSVTSDGSQSRPALAVIARTGFDTTKGALIRSMLFPKPIGFKFYRDSIRFIAVLAGIALLGFSISAVQFVRIGLKWQTILIRALDLITVVVPPALPATLSIGTSFAIARLKKSGIYCISPSRINVAGKINVCCFDKTGTLTEDGLDILGVRPLDRNINRFGELLDDIHDLPLGKDKASFLHALATCHSLKMVGGDVVGDPLDVKMFEFTRWTLEEGTIGRTGVIKVKSGAVAEQAALVQTVVRPPGSAQFRLEDALKGNAKRAHFLELGVIRSFEFVSSLRRMSVVVKRLKSNSMEVYVKGAPEVMMDICEKDSFPEDYDDLLSYYTKRGYRVIAMAGKSIEGLSWLKAQRMKREQAESKLKFLGLTIFENKIKPGTTPAIQALRIAHLPCRMITGDNPLTAVSVARECGLVNPAAYVFSPSFIRGDATGPDTKLEWTCMDDPSWKLDTYSLKPFSPPLHHTAEADDIGYHDYSLVISGDVFRWMISYAPLETLQRMLVKAQVFARMSPDEKNEVIERLQGLGYTVLMCGDGANDCAALKAADVGVSLSEAEASVAAPFTANTPDIGCVLELIKEGRSALVTSFSCFKYMALYSLIQFTTVTLLYSFASSLGDFQFLYIDLFIIIPIAVTMGRTSPYPRIYHKRPAASLVSKKVLSSIIGQIIITSVVQIWAYSWVRGQEWYSPPPSPDANDDGNQLESTNFENSVLFLISCFQYILVAGVFSIGPPYRKPMWTNVLLMLSLAALTSFNLLVLLSPPQAMADLLTLMMIPTEGRLKLLLAVAINMAICILYEGFGYLAVAGIVGRIMKWRKRNWRIRETGGKVYKAVEGGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP44</accession>
    <name>A0ABQ8VP44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_819534</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="439"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="550"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="584"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="726" mass="81477" checksum="E659EA40C96848FF" modified="2025-10-08" version="1">MSLPMLVGGTECGPSNPLQGLSKHLDNDRGLQQDHFGAGRAGPSQEAFRSQITSPLSFDQDTARFFAKSPPPQFYGNIPYDMAALRSSLPAADAQSFKQNVVADWAVDFLTQQPMQASSSQPLAGAATQPTVKPMNSSATSPTTQAVNMIRPAQVMPLGSTWNTTMQFIPSANSFQAMTVPRSALPDTQLSWYKEFDAQQSDSVPIEVLSNANAQDEFSQSFREQDELSRTAGLLLETVKTEKNPKFQNSIFMNLMTQLRDQKVVVRGNEMVENDGTDTVSQDSRVDLKGKGKARASDSPFIPYAGLVSTLGQTIGNNATMAGVSPYNEQIGIQEDANDAYFRQENEDYTRYWNGMDPRKSQGQKVEVDLNWDKLQTDWEKFEASTKGITPVVSYQFQKNNPYLRGDSSRMRHHSMHSDDRLETVLALEAAVQQDMSNASAWFELGVKQQEHERETQALQALKRATELDPTYLPGWLALAVSYTNDGRRLEAYEAIREWVLRNDDHRDILQQHLSQHPSSEEATIQEKFKQLVQCLITMAQQSAFGQIDADIQIALAVLFNSNEEYGKAQDCFRAALSIRPDDWQLYNRVGATMANSGRAEEALEYYYRALDLNPAYVRARYNLGISCIHLKVYISLVLFLTSRILILRRLQRYNEGALHILDALSLQDAEGVHDVEGFNDARGGITSNALWDSLKTACLHLQRVDLATLCDKRDVEAFRFNYQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP50</accession>
    <name>A0ABQ8VP50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_894877</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="8">
        <location>
            <begin position="17"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4496994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="367" mass="40375" checksum="FC2E9B3336C1E337" modified="2025-10-08" version="1">MSGIPPATSEHFYLPPLARAAHAGHVKRCLLGLPDSQVDLDSGRMAIAFYCLGSLDLLKMLQDKTSQTDRESWKEWIWEQQTCGKYGSGFRPSPFMASSMPSEGTRYTDYDTPHIIMTYTALLTLAILRDDFSRLEKQGILLLLKACQRKDGSFSTIPGSGETDLRTLYCAFVISHLLNDWSGVDVDRALFFIASCRSYEGGYGQSPYCEANGGTTYIAMAAIRLAPSNSNPLSLSEIRKTIDWAVHKQHRSGGFCGRTNKIADACYCFWIGASLKILGAGNLVDSRSLASFLASCQFKFGGIAKAPGEHPDPYHTYLSLAALSMFPPPQYDNDTNSSTWAFESLDPLINARGETADWARSHIAIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ33</accession>
    <name>A0ABQ8VQ33_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_756725</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF687">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="378"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="62"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="206"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="534"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="73"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="206"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="790" mass="85731" checksum="DCF38CBC886F0B3E" modified="2025-10-08" version="1">MINAKQPQNYPHPPQPYHTYTNHHSYTAPPIPNSSSAWHHPIHQQPEVHSPLQQISTSLPYNLNVETPSHNDASSQSHPPTPAPTSSSSQTAQLFTASTSSPTNPSSSSNSQDSHSTPMSIFSTTWAIWSRRPTDPNLAPGLVFSSRIRPPDYIVRDALDIRTPPASPTTEATTLPDIEFQQTQEDVEWGVTDSVPEPAVVLLPAASVASSEETSTTATATPSTTLPGSPASSTTSISVSAPAGSSKDTSSEYTEAPTSPELALTSDVAAVSTTTISPKSPLPLKKTWASLLRPTTDPSPADAVTQRTRPRIPTSSIVGFSVPADAIGSSQGGGQAIPTGKRAELLALLNSDLKPASNSGPTSSGISYAAIPSKIHPRGLINTGNMCFANSVLQLLTYSPPFFRLFHELGRIGMEDVKQTSGVQVPLVDATIEFLTEFLPEDRKAKLEEENKKVNARMTKGKERSMTPQPEDDLCPFIPTGIYDALKTKKQFDSMRGGQQEDAEEFLGFYLEGLEEELTTLTETLTHVESSTLLEGKNKKKGATAVEETEEDAPPEAEQDGWMEVGKRNRTVVTRTIKSTDSPITRIFGGKFRSSLRVPGQKESAIVEDWRSLRLDIQRDSIHTIQEALANISKPQTVHLVDPPREGSQLVLIEALPPVLVLHMKRFEYDASVGSVVKVGKQVVFGPELVIGADLLSAKARSNLGSQGVKYKLFGVIYHHGISASGGHYTLDVLHPDRFPRAATAKPREGWIRIDDELVSDVRPEDVFGQGDFDDGGVRCAYLLFYRRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQE4</accession>
    <name>A0ABQ8VQE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_864493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33598" checksum="B3C967936528B10D" modified="2025-10-08" version="1">MVDMRPFLLSSQFTRSVVMSRSPQSPHFQAPLRDQEGWYKPHFEKSTGVPTASWSKNQALEVEVELEGDEVALEDGNQIPCAIAVPSFPPQDASPEDQKEPRLERKSECADRPPDAHDLRNDSENIGVAKATRVLEIKDESAESTIRGQGEIEISNNSIGAITGKPVQLLQNKKHAFEDVDSKDLRLIAFRNFVVGTLNAGALSYLLFLIKILRKIWTMFQNQTSIAVGHLALSVGLFILTRYWGTKSALTQAIGKRSKFSQVIVDTTILVGAFICTTIVWRIISVIGESVSMLRVHRGVLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRF8</accession>
    <name>A0ABQ8VRF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formin binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_893867</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="3">
        <location>
            <begin position="365"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="764" mass="88993" checksum="FDB3BD6863600B48" modified="2025-10-08" version="1">MNLWTEHRNPEGRTYWFNTGTRESVWEKPDDLKSPFERALNQTKWKEYFSGGRKYYYNTETKESKWDMPDELLLVLEKVEKEKVAPLAGAITAPGFIPVGSSTPAIPSLETTTNGVVGAHTGALPLASSTVLPARPNLPEDPVIPHNGFVTVEEGEKAFSHLLRKAGVDPSWTWDQTMRAIITDPLYKALNTLAEKKAVFEKYTTNLKVKEQEEKEARLAKLRPAIRNMLKGNPNVFHYTTFNTADKLFSQHPIWQQAKIESERKLIFEEYVAELKQREVQESRAARSRSVAKVVNLFKQLDVDVLTRWRQAHNLILESEEWNSDSELRKLPTLDILLAFEDYSRVREREYDEQTRRAQVEKTRKERKAREAFKELLQSLVTSGDIKARTKWKDVYPKFRDDDRYINMLGNPGSNQIELFWDVVDTLDQKLDAKIAIVTNAIAKVDGPAKGDSEGKEDDDAPERSGLSITAATSEEEFLGVVKATLNEDVKSLSREELHLIFGTLHDAAVKKQADEKRRAERKQRHLQEDLRYALRKLAEPLDLSLSFEEAIPLIEHLSEFQAIEDEENRRTAFAKFVKRQKERIREAAGSEDGGSTTSRKRKEPPRAEQSREPERGDRDRRDRDRDRDRESSYRERERGKDHESRNSRHYRHDDYDRKASKDYDRDYRSKHHEKDDRRRDRDRGRRQDFPSRDWDEPQYRREEREKSVSSSTYKDRDEPSKSEKREMEEPSIDDRAEKRPRYDEPAPTGASSAREDTPEEGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRH5</accession>
    <name>A0ABQ8VRH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anticodon-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_900734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="122"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="374" mass="42539" checksum="95B9A9F79BE3460F" modified="2025-10-08" version="1">MPPSRFEPSIIKNKIKREEIANKNKKAKSQDKLQRRLARAKLEANDPTAKKKRLSTNVPRTLDNMREFDPSFLTADPSSSSQTQDGPSSSPGEPAYDENAEDLASDPFAAYFNSEEDPNIPPKVLITTSPKASKPTYEFCDEIVGIFPGAEFIRRKKGKGFEVGRIAGWAAGRGYKHMVVVNEDMKKPNAITLIHLPNGPTAYFKLTSIELTKQIYGHARATPHNPELVLNNFVTRLGHTVGRMFQTLFPPLPEFQGRQVVTLHNQRDFLFFRRHRYAFRSPEKVALQEIGPRFTLKLRSLRKGIPAVFNLAEEPKGLEFDVDDLKSSVEETLDSDENKQNASEAPEKVIPPKQDDYLWKWKPELETTRRTFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRQ7</accession>
    <name>A0ABQ8VRQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_819513</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="764"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="229"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="335"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="712"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4498165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="817" mass="93403" checksum="C83344EA5B6D04F3" modified="2025-10-08" version="1">MAETKKRFHSVEDDSDKVIVKKHIITDENGSPRVNGVGKGHIDDVEPTADDKLELFRKEAIYRRMIHYSRLNEASQKRISELEERKSTCEAGLAAMSACWMQLVDAIRVLVVKQESSQPIEVSPSTQDLQDLFTLSRYVSDDSMPELKSALEKSRHATQELVMKFVQKGSPHVAQDTSLKEYQRTQTECAALKAQVQVLQVRLSDSEELGRKLRQELSEEQNRLQRLKSKTVQANLPKAGMSSGESSEATEDAMLKPSSPAPNGFTPKMQEEWEERVAYQTRLLREQDKIIDELRKTKSALELEINKKVLTKADVLNSPFYQRVLQRSASALNAASAKEEELRLLKLEYGQYRDEREKYEKELRDESAVAINETLALIARRDADNARLREDRDQRVVELHERRNKESVKIASCEEYKSLAISRADRISALESQLHRSKLKLASNAGREDIVNFLLEMPDKNMEFAQYIQARLSETETRLASHEEVLAKLNHDHPNVAHYVQSEVEARQKLAEVTAQLIKYQSLYGELSSVPPDSLANELQRKEDELRRSRLLNAQHAQAESALYTETEKLASAWEALDGQVKNKIFDLSAMEDRLTKATVERAKSDNKFYAASRERDAVESERKNLIRNLEKQGRVLELSKDNEQRLNGLLAATQDELAKHKAYCQEAHDNAVKQLSLKSLELHERASEGTKTAHIYRDQIDKFQREHHSRQEALRKEMEAMSAAKMALEKERLALQSKAKFDSTRHQHKTEDPDAGLMALLKCSTCNLKFRDTILTKCCHTFCRHCVDARISSRQRKCPACGLGFAQSEVLKIYMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTW4</accession>
    <name>A0ABQ8VTW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_813789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="129"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="263" mass="27991" checksum="56ECA50CA0ED28AF" modified="2025-10-08" version="1">MSSSHYSKSVHSARSHRDSDIESWGTAYSDSRTPTPTASNYAQPSGAYSHRSNPSYPSPSYGPSSPFGGFSASLGSYPQTPGTPYLGSVPLPQQYINTTAPQTPYLSTIPLPGDSTLNPLLSYPPKAVFNVTYPCSSIAFRDGLSSNDVALYPPVQSIVLGLSFVCAGKRTSIQASSSRGLTVHDVFVALSNLLLSTPTTSDVANIQPDVYARGKLAQSARRRSNGYPHLRWTDLLGERVYFGGLANIGNGVYEVGFVSAPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTW5</accession>
    <name>A0ABQ8VTW5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_609760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046064882" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="49"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="15788" checksum="3C27DF20A941116E" modified="2025-10-08" version="1">MQIHNWVLCLLVAAATGYAQDASSREPPNELVIETIHMPEVCTLKAGTEDQIKVHYTGTLHATGAKFDSSYDRNSPLPLKLGVGQVIKGWDEGLQGMCVGEIRLLTIPAHMAYGSRGFGNVIPANSALVFKTELIELNPKSRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU95</accession>
    <name>A0ABQ8VU95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatase phospho-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_819456</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016965">
        <property type="entry name" value="Pase_PHOSPHO-typ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889:SF12">
        <property type="entry name" value="LP01149P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889">
        <property type="entry name" value="PHOSPHATASE, ORPHAN 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06888">
        <property type="entry name" value="Put_Phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031051">
        <property type="entry name" value="PyrdxlP_Pase_PHOSPHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="240" mass="27366" checksum="6DA8AC9564ADBFEC" modified="2025-10-08" version="1">MAGRQLVVFDFDWSMADQDTDRWIFEVNAPDIRRKMEDLESSVQWTDLVAQSLLEGYEKGIKRKDIEHALKIIPYHPAMVRAVTTLKARGSTTFLCLSNANSVFISTILQEKGLDTLFEEIITNPAEWDTSGLLKLRRRIDPEGPQHGCKIGCSPNMCKGEELDAFLARHDSTYDRIIYVGDGSNDFCPVLHLRSQDIVCCRTFGGLPKRIARDGERFGLKCQVKYWTGAWELEEIFNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU97</accession>
    <name>A0ABQ8VU97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RanBP1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_569239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13179">
        <property type="entry name" value="RanBD_RanBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045256">
        <property type="entry name" value="RanBP1_RanBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="18"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="22729" checksum="8DA8EC7FE1EADF07" modified="2025-10-08" version="1">MENTDPLAPRQEEEADVHFEPVIKLTEQIDTKTHEEDEQVLFKMRAKLFRFDAASSEWKERGTGDVRLLAHKETKKVRLVMRRDKTLKVCANHSISADMRLQPNIGSDRSWVWKVAADYSETPPTSETLAIRFANSENAHEFKKEFEAAQKTNAALSGGAPAEAPLVEEKKDEAEKEEKEDKDENKDETKDEKKEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUQ8</accession>
    <name>A0ABQ8VUQ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_752469</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12676">
        <property type="entry name" value="RRM3_Nop4p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034808">
        <property type="entry name" value="Nop4p_RRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="22"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="139"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="243"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="487"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="410"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="702"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="426"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="710"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="942" mass="105414" checksum="3A2812177B83373E" modified="2025-10-08" version="1">MSASLGKRKERDEEGAVKQHGSTLFVSNLPYTATSTDLQTLFSDIAPVRSAFVVTESGKGVSKGVGYVSFSIKEDAEAAFDKISTDGLNLVGRSLRVQWADSKPKEKGEKGEQVKKETKPIPPPRPSYPKATHDPLAIRTIVVSGIPAEIDTKVLWKKFRKCEGAEKVDWPVSHSSEQADTAHVVFATPQNALEAVSKLHAHVFKGNLLSVELKKRLDNLTKSMVNTKQASTTSTAAAPTRAARLIVRNIPFNTSQQDLRALFLPYGPIYSIHIPLESKTDDANVTKDGEEPSRKSNSQPRSHSRTRGFAFVWMNSKKDAERAMEGCNGTVLRAGMAENMISDKQKRKKQRRLEKKMKERMKKGTTGEEKDEDEVEESEHEEDDEHSLDERIIAVDWALSKDKWEEEKAKLGKADDDSDEIKDDAASGSGSSSDSSSGTGSEDEDGIGLHDDGDESGSDYSGDDDNKSDGEEEVPVKPELPAPEAGTTLFVRNVPFTATEDELRTLFRAFGPLRYARITMDPETGRSRGTGFACFWNKDDADKVVAQSDLLRAETGSNDTPKQNPFKLPSILTPDPSSSLARSLVLQGRTLDVVRAVTRDQAGKLKEEGERRREKADKRNMYLLREGVILPNSPAATLLSPADLERRSSSFTARKNLLKTNPSLYISKTRLSIRQIPIFVTERMLRRLAAHAVKTFNKEVKGGERKGLTEDELTVEPEAEAEGDSEFQGKTDKEGKKRKPFGRSKPNLTKQAKLVRQQERVDQITGKGRSKGYGFLELNTHADALRVLRWANNNPSVAELWEGWWKEELVALLKAEKSKPENEKEESRIKRVEGEIEKLESAGGGGTALKKSRGTLIVEFSIENVQVVQRRRVMQDERRKVGSIPVLFRTLTLICDCSSPHRLIRHKRHKRWIQRRRRWSLLKLGKRNLKNRYQGRNARLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUR2</accession>
    <name>A0ABQ8VUR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_811755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="96"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="188" mass="20962" checksum="7113E8D44827297F" modified="2025-10-08" version="1">MKCYTGNNTDILKLYARAMVQAAKLVGHIFVTTEGDLWPAPMISAAFCWEPGQSLWATKEQREVGFDQLSAAISPDTRVFWGEIKQVGDTLKAEHGLSSMPTDTFYVNMLVTDRHFQHRGFGTAVMKAVLAFAAKDGRGWDVGLITQSPENRDWYVSLGFKNVGSCKISAEPYGDFVTMFVFDPYKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV74</accession>
    <name>A0ABQ8VV74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_893029</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4500287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="542" mass="61505" checksum="CA6BA4C36338E3F9" modified="2025-10-08" version="1">MEIERLLFENATRVSLFVVIALAYFLYRRYTRISVSHIPGPEPESFILGNLPELFQSQVGVPDFKWKQQFGDIVRIKGPFGEDRLFISDPKAMQYIFHTAGYGFLKWPERTEISRVLMGRGLLWADDAIHRRQRKVMLPGFGAPECKAFVPIFLKAASALVEQWNDLLASSMDQSVELNVASWLSRATMDSLGEAAFDYHFGALENKENELMKAYFGLMSDTLGQPSRQAIFTQTVMPVWYLRFMARCSNTRRMVHARHTAELANDIAQSLINMKSEALLYGKENKDILSLLVKANASENPASRLTDEEMLAQMRTLLLAGHETSSTSLVWCILELSRHPEVQSRLREEIRATERRLNGRQFTASDFDNMPYLAAVLKESMRFQPAVYQNYRMAAHDTVLPLSKPITTTTGETISSLPIGKGTKLVLSIAAYNRNKEVFGEDADVYNPDRWFRNSEKKGPTVGVYGNLLTFAGGVRTCIGWRFALYEMQSLLVEIINNFELGPTKELERLRREACLVMLPTLEGEEIKGENLPLRVSIAGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVW5</accession>
    <name>A0ABQ8VVW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_863735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045239190" evidence="2">
        <location>
            <begin position="21"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="235" mass="26220" checksum="AEB61AB615F14745" modified="2025-10-08" version="1">MVYSHRVIVYTVIVASSVLAVPLQPSRALSDTVSTPGTVAAAEPTVDVHNLGISVLLKDNESHPLERLGAEQQHHIDVDESPSLLGNETIFNNHTAPTHPDHTSESSNSKENQSLSSSSSYITPPGGTPSFSLLPIHIERRTTMSDKDALFYLKQCKVPARWTLTSEFRAMPDNAQNIRNSDGDWTQFKEMSKVDQLIESLQRKMPKIKPMVPIPMLVEAYYVCVRNQLLRWCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWN9</accession>
    <name>A0ABQ8VWN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Magnesium chelatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_811467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="65355" checksum="0A9F2D9C530370CC" modified="2025-10-08" version="1">MSDMADFPITRIGTPSFVPLLLTNARLASGGLPIDPVLFQSILLCLIAGNKHLILRTVEDDIGLVVKLAVKTLATVFGLLTHRIRIHRRAGTTIHDPSAIPGISTFLRSLFIPVSGTNSSHFGQDEVSTLTGHGARRYRKRPDSRSRSRSATVRSMTSQYTKSLSYPNDLLSAKSLNTAPSLSLSASEPFGDYNSPSITEVVSPTHINTASRNSSLSALSQPTFPHSYSDPTPLRVVRDPTQIQLPDALVLSGLENASLASQRALTEVLIQRRVVIDDTDLSGVWPFPKDFILVYICPLDERERPPIHKPLLDKFALSATVLLHPTIRALSKNFFRSVSHRSSPILSPLPQLANSPPTSPPFLAQALPHRHISPGIITPSNGLPAVITPEIMSLLKEVYSRVHIPSNLHLYVSDLFSATRHHHQLEGRLVSITAIKDTSELSRAARVLGGDPTGMELISETLRSDDARTDDNSTTDGETGDERFSKVLNDVESAFVVIDPQVDIETHLSTELAHEDSDSVRVPALPVLDVTQADIARIVPRVLTHRLRVKDGPEDEVLASAVFGAAFSATSKEERGRKRDRNRVTVKELLVEILQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX59</accession>
    <name>A0ABQ8VX59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_807494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00238">
        <property type="entry name" value="KamA family radical SAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538:SF0">
        <property type="entry name" value="L-LYSINE 2,3-AMINOMUTASE AQ_1632-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="LYSINE 2,3-AMINOMUTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01070">
        <property type="entry name" value="PLP-dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="59"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="38386" checksum="9C801B67E0E71797" modified="2025-10-08" version="1">MSIRITPHILSVIDWTKPLSDPVRRQFIPLKSSFVKDHPKLQLDSLNETGDSPTPGLVHRYRDKALFLAVSVCPVYCRFCTRSYSVGGPTEELSNKRSFSPTRRRWERMFEYIERTPQLSDIVVSGGDSYYVPPEHLSSITERLLSIPHIRRIRIASKGLAVCPSRILTPEDAWTQAIIDISATARRLGKSVALHTHFNHPAEMTWITRLAAQKLYEEGVVVRNQTVLLRGVNDNAETMGLLIRMLADNNIMPYYVYQGDMVSGVEDLRTPLSTILEIERHIRGSIAGFATPNFVVDLPGGGGKRLAASYDTYDRSTGLSTYIIPGKNGGKDRVYEYHDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX71</accession>
    <name>A0ABQ8VX71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_279717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="265" mass="30089" checksum="BD9927796EAD4658" modified="2025-10-08" version="1">MHDHLFGIDSESYTIYSLYSPSPHIQMLRSIHHTPSEGDVRIVRNLLRTFLPLELVDVIIADAEYWLCIHVERSKQIRVDARIALGQGFKLAWCYLVSPPIPETLSSVRHGLGQRRVRKVQLKVQGHDLVWATNLSPSSWYEATIIKASRQPSLLWFPAALRGPVDPASHLARPHFNQVFAGFTRWHIASNELGNRTKQDHSVIWTEEEVQGPRDAGSIKGREGFGHELVRALQPGDRIAILALAQQWGWENHVYSASITIQYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX74</accession>
    <name>A0ABQ8VX74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_807568</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="21"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="554" mass="60316" checksum="A36CAB4EC73ECA84" modified="2025-10-08" version="1">MGSVVKSERVGLFQNVRVYWLAFIAYWGILLFGYDTGIAGGVVGNLYFEETFGIANSTGTINTKKSDDVSSNVVSVLQAGAFFGALVSAPVSAKFGRKWPLFIYTLIFAIGAILTIVPSGSNPGRGLGEIYAGRVISGFGIGAITAVSPAFVSECSPKEVRGRITGLFQVMVASGIMISYFINLGVGLHVKNNPKIWRIPFGLQLVPAGMMALGLLTVKESPRYLASVGRNEEAINNLAYLRRSPADSESVVLEMAEIEAAIQEERLARVSLGWREAFFGKGNAIRFLIAFMIFLLQQWSGQNSVTYYAPQIFASIGYTGTKNSLLASGVLGAEFSSFRILDILLTCRSLGVVKVVTVSTFVAFGVERFGRKRFLFISSMGMGILFFIIGALLKTHPPPAASANDAPSSPSRASQAMAAMLYLEGVCYVIGWGPLPWIYVSEIFPTRTRHYGLALASASQWLWNFVISKQTPIMKTELGYKLFLMFASVNIGALAVFSLLIPETKGKSLEEMDIFGAVDVEQRQKDIMVQTLIHKQPHRQSPSTRNSISSDNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXV0</accession>
    <name>A0ABQ8VXV0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_806345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12372">
        <property type="entry name" value="RRM_CFIm68_CFIm59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034772">
        <property type="entry name" value="CPSF6/7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23204">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="36385" checksum="FB68A2190C1AEE74" modified="2025-10-08" version="1">MQQDDFDIYGEDIQQQVQNEEIEPRKVPTEVNKVEPSVGEKRERENSGEPDEYQGEQSIAVMGGATQTITNPGLINTQSGTNSDALYIGDLQWWTTDEDLRQVGLMLGLNLDHKDITFSEHKVNGKSKGIAYVECGGYDNAVALKNWFDNNDFQNRKVTATLSSSAQGNPFRTLPKEPPVREGRVQPQQSGTMQPQVNTVRGGGTFRGRGGMRGGVPNGSGGSGNMGMANMGMANMGMNMSNMMGNMMGNVGMGNMGMSNMGMGGFMGGGGAFSRGGGMMPRGGGMMARGGMMGLGMGMMPNNMMGMASGRGGHLNPAFVQGGGHFHGPDGPRKRFRPEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY36</accession>
    <name>A0ABQ8VY36_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubinuclein middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21838" checksum="65ADA34A57E84235" modified="2025-10-08" version="1">MPHEEHPYVAVTTASAPITRTPVLGVDRVQEKEYTRSRKTVTFSTEPEKKQNPPAMVFEDNSDDDFLIPKPPGEVGRPGRGGYSLFEVLSWPRKKYDKVKKFINNLVEDHLNCDLSMSEQGAANVKKVRQLAVEKYIFLKEYSGLWAVDDFIRNHLKYQKAVLRKERLEKIAAEARSTLVEKGMRRASSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYA0</accession>
    <name>A0ABQ8VYA0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_749311</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_bL28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_bL28_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="180" mass="20605" checksum="7D3F27483543A838" modified="2025-10-08" version="1">MFWTFPVASVKAQLVSQPFKRSQLGLFQGKTKQYGNNVPHSKHKTRRTWLPNIQRKRFFSEALNENVRVKVTTRALKTIKKHNGIDNYVHNMPSKTLGWEGMRIRQMVKSALKDPRMPAGLSEEEANVWIAKRTEELEIQTATEARSVEIARILRNELPNLTTARNATEQALKALGPSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYC5</accession>
    <name>A0ABQ8VYC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_203154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="373" mass="40889" checksum="69AF92BD4186A90D" modified="2025-10-08" version="1">MAPPRPPFGTDEPESIYETPNHPQRRIRQPAPVDPNSRTSAYNVYNNYIHDDSNRQSGIDALGAGFMNGSMDDDDDELQEKYNPFTSAKEQEASKHAMLAAAIGPRKTPTPPPQYIASPRPGYAASVEALSRPEPAAIPATRQPPNGLSISTSNNPFATPMDHQAFPNGPHIPQPIAVPNTPHPLQPPMTPITPVFARPTKQQDIRFDEKPIMRGAGEGTSIPSRGEKGDDFWRRFSMVVKEENSKPSQQKQSSWLKTTQGRTNSMFRWVFFIGMILTICALGAIGLWWYASHNSTAHDQPHALGGSESEAGSTSTSAVGQASSAGVLQTSLHVSPTNTVARRIVHELYETQPTGLPLLSNRHKQKLHLNRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYI0</accession>
    <name>A0ABQ8VYI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Volvatoxin A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_892525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.198.10">
        <property type="entry name" value="Delta-endotoxin CytB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035918">
        <property type="entry name" value="CytB_endotoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001615">
        <property type="entry name" value="Endotoxin_CytB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01338">
        <property type="entry name" value="Bac_thur_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55676">
        <property type="entry name" value="CytB endotoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0749">Sporulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="22937" checksum="C710BCE5691B9000" modified="2025-10-08" version="1">MLIAATTFNQFSKLPENLVTTAIQVLQFSAHFVDLKEPKTFHWDQFLDGINSYKGDDLTFDKYQNNTINQQSATVSIMVDKIVDFLRVVLSVALSEEDISALSKNIETTFTNLKEAKDNGWADFSTSSSSSNSSWEYRVLFAFPNPDLPDFFYSLVTTIKLEADIQEESSWWGLESSTRKNFAATIDAMELVVLKGFKDPLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ92</accession>
    <name>A0ABQ8VZ92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_907033</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the GAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="122"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="131"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="20148" checksum="58E11F1BB5C344A0" modified="2025-10-08" version="1">MSRGGSRGFSRGRGGGRGGFQQRDFGPPDTVLEMGSFVHAVESEMLCSSTIADKVPYFNAPIYLQNKSVIGKVDEILGPINEVYFSIKMSEGVIASSFQKGDKVYIGGDKLLPIERFLPKPKVAGERGRGGARGAPGGRGRGAPRGGARGGRGGGGRGFGGDRGGRGFSRGGGGNFSRGRSGFRGGGGGRGGFRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W075</accession>
    <name>A0ABQ8W075_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_479680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF90">
        <property type="entry name" value="CNNM TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="8">
        <location>
            <begin position="49"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="387"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="571"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="639"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="417"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="683"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="726"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="737" mass="79780" checksum="0FC2898E80B33065" modified="2025-10-08" version="1">MPPTPNFGRYGPHSSRLVYSVFTLLSAGISQLRGNNGEDGTVHRLARRKPAEDIVFPILIPILVLLSGLFAGLTLGYMSLDQTQLNVLSVSGSPEQRKYANKIKPIRSNGHLLLVTLLLANMIVNETLPIISDPVLGGGVQSVVVSTVLIVIFSEIIPQSLFTRYGLYLGATFAGPTRFLIFGLGIVSWPTAKLLDWIVGSNHGIIYRRVELKELIRMHSSSSPHGGDLNHDTAAIIGATLDLQEKVVAQAMTPLSEVFMVHIDDNLDYNLLKQIVETGHSRIPVFEEVEVPVAAKLGWAHSQQSKREKKIIGILLVKQCVLLDPKDATPVRQLQLNKVPFIPQNETLLGILDKFQEGRSHIAIVSRFSVEKAKSVKKAVKQTLTQRLKERVGMDSDSSDSSSDSSGESETEGSSTKSKRRSFRKRFKRGSKHEKVDKDATLKGDSPSDSGKAEQMEMRKVDSAPGAFGISKLEANMPADAVLTEHGAAEFLQSFDPAIMPLGIITLEDVLEELIGEEIYDEFDSEGAHGEPLPVQNTIVSPIPVAGTMSSTMLAPLSNVRNLNFFRSRSAPPTKRVLRAPAGNPDPPSEKDTTTSETTMEPVKNGVTPVHADGILKGKSEGLLTPVTSEPAPPAAIEARLLDRKRRKASSTTTQTGGEAAPTSVGAPRPRQGPKSRFKSGPLQKNSVVAVPQDSTSGIPIPEIREPGNLKEGSLSTAMETGEMGVPDEQDMDGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W077</accession>
    <name>A0ABQ8W077_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_805633</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of an histone acetyltransferase complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The PHD-type zinc finger mediates the binding to H3K4me3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ING family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="301"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="356" mass="39969" checksum="FBA0E333CAA6BEEF" modified="2025-10-08" version="1">MSRKRRRSQAFPDPDEDIEEEEEAVLAGEGLEDRRLEKEREIWETVKEEHFEIIDQVPLTLHRQYNLMAELDQQTHGYLDDLVPLLQKYVAYRRNFEVEASTAPTIPSTSTITPNNTSAPPIPKTPLRSVRASILTPRPSTPLLLPAERIKPPETGKEILSHVAWLAEELVSAAQEKVNLARAAHDYISRQIQVLGQSIKEQEASIALGIRPGTQLAPILLPDVAPPSRWTKNTAGGLVLDDDEDEESVKAIPTTQGDLLVEAERPSKRSTRARRGKRSSVLGTDQPMSLKITLPAMYDNRLYCYCNKPSDGEMVACDNEDCTNQWFHLTCTGLSQLPDESETWYCDDCDPDKSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0L1</accession>
    <name>A0ABQ8W0L1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="945"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="982" mass="109329" checksum="6510D78E328935F9" modified="2025-10-08" version="1">MLLNLRQFRGNAHGLKNTFEVQRWGSTPCSRASTAAAVKSNISHASSSNEIPRDAKDDKNKKRKGTTTQAKLNGKGVNVRSERSSKNCVNARRNHGLKSIPSHNPLLFSIERFIASQPSDSQLDSFIHRRLSSPQYLQQYTHAASRAALLEQLVQLLLSKRCYVQAAGVYNRMRDWEGYVPASGRSGGEGWKTEAMMLGMALAMSEKTLADSAIEIGQTISTLSIIFRHTLSDHLLLALVHLLSELGTGNALIERVIWVYIGCREQTSSHSAPYIPPLSIVSLLAGILTKQGKVREALEFVERCDDLNNTDSQYLHVMARSHPYNTILASLSSFSAQESTEVIDLVLTIMASRDIPSDRSLINILLRDQADRAGGHRTSSNSSSSANTSADSGQTPTSTVDDASEIGQIWNSISGHSEDTKIDRRERGKLRKTEQKQAFEKAFTLYGTLCQAHDAQESQGILPTVSVGTESARNETVSYKPSFRPDFFTFRTLWDLLVRRPGWRFSSSPLPTSGATDARKANEDIIEDEYGFDLTIGSDEFDEHEFPSDEPSDVDDNVSPPVAPVLPPRKLFHDMMRYHFSHLIKVPTTSLQKPKQRNNISNRSNGDALDVKATAQSQFLLNTALLTFLNRSPSGGGADYAAAMVVLKCFGVHSYGSMGLALMETQEEIEGEGRAQTSVAEGGTTAAELTSLPRIPQIPVPLRTYRIILRHLTQSVTSDLRLALRQGTGKGSYWARWVLSIGAGDFRQFRWLLSSAASRRMQADQVHDGVGKKENTDKTKRPTEKIIGRILKISSIPVSNATPLDPFSLQHSTELRAATTNPHHHSFHRDFYYFNKRDPLISVLSSTPSALSALSALYVPTYAQISRTAPLPALIYYHSDEPSRSHGVKGVKNKPSLHNRLQSRSLNPAPLEIMIKRAWVASNYSNYTDYPDSPNHSEYLREDGKETEEQDGEYEDETRRLELLLRIFDMEVDKARREMIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1B1</accession>
    <name>A0ABQ8W1B1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetraspanin Pls1 family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_748899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="25450" checksum="79FB4AB1A994255B" modified="2025-10-08" version="1">MVSRKLMGFWALFDVCLLAAGVVSIIFSVVYRKQDILLNLTISKADLTAALVMGIMLVATFIFSIGAIIQKNHVTIGLVILNYILVADAVVVLVIGSFVWFFSLQQRNNYHALYVELPASSRVFIQDKFSCCGYFNGSDAVEPSTFCTSSQIAFTNALDPSDVNNADSFCVTKVTAFTDYTLNQMFSYTYGFMPIVLGLLLFSLCVINKRKEDERFKKIDAKRGGRGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1D4</accession>
    <name>A0ABQ8W1D4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="25187" checksum="FD79A5A8C75C80F5" modified="2025-10-08" version="1">MSDSTHSMMHDESTLFTSDFGSEMLNYTGGIDLSDLCLVDDFYSHSGLSSPLFPAYPTSLNPMPTSPSPSPRLPTPILPVPRLQPTSLGQSTPISPPSTASPAISPTPISKAFKCGNRGCSRTTTSKHCTTKLCTKCCQTRTDLQCPHHQKNSQKPSTVPQLALVPIPQPGSLTESNSVGSTGTLLAQSDPLPIRTLSKQMPQDMAVRFKQQQERKEQKRCLTDESGFSHGVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AUS0</accession>
    <name>A0A9W9AUS0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_420940</name>
        <name evidence="13" type="ORF">C8R41DRAFT_749632</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
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                <person name="Konkel Z."/>
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                <person name="Sakamoto Y."/>
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                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
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        <subcellularLocation>
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    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H4 family.</text>
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    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
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    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
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        <source>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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    </gene>
    <organism evidence="15 17">
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        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
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    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
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                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Sp2 HRB7682 ss15</strain>
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    </reference>
    <reference evidence="15" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
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                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Sp2 HRB7682 ss15</strain>
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    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
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    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
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        <subcellularLocation>
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    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H2B family.</text>
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    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="41"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4474148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4495791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="146" mass="15374" checksum="AB59EF025FE65082" modified="2023-11-08" version="1">MAPKPASTAGKAPASTAGKAPAKTEGSKAAKKTSAKSSAGAADGEKKKRKKARKETYSSYIYKVLRQVHPDTGISNKAMAILNSFVNDIFERIATEASKLATYSKKSTISSREIQTSVRLILPGELAKHAISEGTKSVTKFSAGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DZZ6</accession>
    <name>A0A9W9DZZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_499948</name>
        <name evidence="11" type="ORF">C8R41DRAFT_893071</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000003">
        <property type="protein sequence ID" value="KAJ4493832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DZZ6"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07857">
        <property type="entry name" value="STKc_MPK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="372"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4493832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="433" mass="49035" checksum="6637586934EF3FB3" modified="2023-11-08" version="1">MQRHSFTALNSTFVVDSEYQFVKELGQGAYGCVVAARHRRTGDGCAIKKITNINTKRILTKRCLREIRLLHHFRGHKNITSLYDMDIVFQPNGNFDEVYLYEELMEADLHAIIRSGQPLTDAHFQSFLYQTLCGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGYTPGSGTSKVAGNQGFMTEYVATRWYRAPEIMLSFANYTTAIDVWSVGCILAELLGGKPIFKGRDYVDQLNQILHYLGTPSEETLRRVGSPRAQDYIRSLPIKPRVPFSTLYPHANPLAIDLLSQMLRFDPAKRISCDQALNHPYLQVWHDPTDEPTCHSKFDFSFEEEDSIDGMKKLIVEEVNAFRAEVRAQARAASQIRRQDSLPIPSREEILNSPMQGQEGTTSNFTAPPQNQRPPSPVMDDPSEMLERELAGAHISDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW56</accession>
    <name>A0ABQ8UW56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Plus3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_872378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000157">
        <property type="protein sequence ID" value="KAJ4463616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.200">
        <property type="entry name" value="Plus-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004343">
        <property type="entry name" value="Plus-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036128">
        <property type="entry name" value="Plus3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13115:SF8">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03126">
        <property type="entry name" value="Plus-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00719">
        <property type="entry name" value="Plus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159042">
        <property type="entry name" value="Plus3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51360">
        <property type="entry name" value="PLUS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Plus3" evidence="6">
        <location>
            <begin position="218"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4463616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="549" mass="62077" checksum="3CDEBFFE88B6197F" modified="2025-10-08" version="1">MSDFDDELLELVEADPSKERKRKRSNGSKSKSSSHSSKRRKAEVSDDEPESEEEEDDPYPLDGKYMDEADMQRLLQLPEVEREDIIATRMEERQKVLDKKALVLLLKEQRERDRLGDTDGGPTGVAKAAKRQHTARGATKEKSNKLDELKAKRKAKDEKSKNRTYSPKRERSSSPMDMETSSSDEDEDGVITKDEQEEERANRLLNGGPSTVQKNEIPATLEDLERCRLSRSSLLKHFLSPWFPQYIKGMWVRYLIGGEGREPVYRICQVDHLVDETVKPYRIEEKWFDRQAELVHGQAKRKFNLDQISNSRFTEKEFDRLQKTLMQEHVPLPTKSSIDTKVAEMLRLTSQRWTESDVSNMLNKARTLGSQRPPGWTTLERSRLNQARTLAFRRQDHSEVAELDAQIADFDARYGNGNSNGNQDENGRNSSGSDVLIKLSEKNRKANAEAVRRAEQQEAERKRRERKLAMNGSGAATPVDPSARLKIVPRTLIARTPTPGPSRPGTPAASALSKEATHSASPLSGSSKSNGQSFEASVIASLEVDLGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWC3</accession>
    <name>A0ABQ8UWC3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6830 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_927248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000153">
        <property type="protein sequence ID" value="KAJ4463780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049233">
        <property type="entry name" value="DUF6830"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20722">
        <property type="entry name" value="DUF6830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6830" evidence="2">
        <location>
            <begin position="67"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4463780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="304" mass="34407" checksum="CD4233C8298BF3D3" modified="2025-10-08" version="1">MKDASVDFRLEDVEGDEGQGQGAEGLQIDEEEDTELEITKISLTEKLVTHLNPVSKKLFGSFRPKQNFFLKARLLKRAPSASLPYPSFVDNVTGEISAFSLVCDPDLKTQTIKEASKLYSLSDFHGACSDLIDHIKSGINIFTVGGRRTGNSQSPLPFYRVKLWSRLRIQSRTYFNLNLLTDPHTIFSAPPGPGWEFGRQNAVIINVDQSFQWPRSSLEGHAIVLVKMIFTVAQPRRPSLPIEGTHHFLAYCEHLDIIIPQDVLFSRELGEQMGLLWEILFLFRNSVLLQIFVLSIEEILTLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX60</accession>
    <name>A0ABQ8UX60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_118217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000139">
        <property type="protein sequence ID" value="KAJ4464569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="39305" checksum="F2FE224FAFEA4878" modified="2025-10-08" version="1">MTITQSPLINPSLAHRKCDSLKFRTFGVESVLRRVNVAVLCENSTTFRRLVLENRDANTPIMLHGPTARQFDHLLWGLGVDSLPQPCDEEDLECLLDVEELSRHYSIHYLQIRAESTVVAVIAEGTNSAVLSCKTDSLVRMLRITIRVHNNTLFAFLMQMWTWRLHSKELDRTIAIRVAQPSRWDYDPQPFLKLLGHAFYAVMMELESKLSSGQRIDLSSHLTQAEMIHVRCGYHSLRSWWDQIASKPPVYTHSPQCMYPERCSYVWRIRFAWLAEKDKIPFPKVDGIRRLQEIHKFIAADLFLIKNMPETCRHSALQELLKRREHLLKTVHHHFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXW5</accession>
    <name>A0ABQ8UXW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_892104</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000161">
        <property type="protein sequence ID" value="KAJ4463529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4463529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="540" mass="61366" checksum="63D520F6CEA4255A" modified="2025-10-08" version="1">MTYLFHHLSKWTLLAGFAAFVYLYRRVFALGKGHLPPGPRGLPLVGNLFQLSMEAWVTFAEWKARCPLVYISVAGRSIVIMNTHKVAADLLDRRGPIYSDRPRFIVASEILTGGLLVVFTQYNDIWRRMRRAGHEGLSQSASADFYAPQSREAILLVDGLLKHPELWNEEIRRRVFLHLRISSREISMYYFSSATASMIWSVIYDKPPITSTQDPQIARINDFITRIVRAAFPGAHYVEFFTWMKYIPSSIAKWKREAEEWYRKDSELFEGFFLEARQRVTSGEERSSFAANLIRDSERHGLSDKESAWLAATLYTAGAETTAGVLSWFMLAMILYPDIQKKIQQELDTVVGRGRLPTFADQAHLPYLQATVREALRWHPVDPVGLPHQSTQDDWYKGFFIPKGTICIANVWSLNRDVEAYGSDASEFNPGRFLDENSQLKPILADTKEEGHVTYGFGRRLCIGRHVANNSLFIDIACLLWAVNIGPVHDSQGNPIMPIESKSINDGLVVRPIPFNCTITPRFTEVKTLLAQSKELAGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY31</accession>
    <name>A0ABQ8UY31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000125">
        <property type="protein sequence ID" value="KAJ4465576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="102" mass="11988" checksum="C1BFC9E8EA0E6704" modified="2025-10-08" version="1">MAQLLADNRQTWEGQVRANTYHHHINWKLGWLMMDATRRRKSPPEMPKAGPLELLRKRKRVVDSNEEEEEEERQGSGEEEEEQGCGGKEEEARSEKGKEREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYV7</accession>
    <name>A0ABQ8UYV7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GDP/GTP exchange factor Sec2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_859474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000136">
        <property type="protein sequence ID" value="KAJ4464688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="458"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="56805" checksum="805BB8C375968753" modified="2025-10-08" version="1">MDTLTSPQPSLQFEVPPSADSSTSFAPIRPVSASHKRPFSIDLSLELERQLDMESLPPTPAHNATVHANSAPVIAHFRDSLDPDVLAHIISQLRRSLSDLSKEKDDLVSLLSSAHSREAELEDALQHMTDKATHMEEELMEVRQKNKDDEEAISMLRTKVEESRRGLMRLQTENRRQSMQITPLDLSRANLNSLSLSPPSKRTSFTPLTGSFNGRPANAHRRISSVSDSGLQALSNLNFGLALSPEHNTQVLTLPGENSNPTPSPMSNRRMSGFFAGHSSGISPSMDVFSSHTSAEIHALRKEISTLKSDLEETRHELTEAVEAREASETCVSALRTFIEENNVGSGPRLNGSDNASINLPHPPASSTDNEADASSIKSGWGFKLWNTKATPTLNNLHSPASASVDSPTLPSAAMQTPTQITKKIGGFFSRQASISSVTAVAPPASVTAPSLQARESMYSYESKSSSRSDTSSIAEPLSPADDEDDSMNIMVREGSSRSMPHDPLDLVAVDLRESGKKSLEVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZK6</accession>
    <name>A0ABQ8UZK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_925818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="645"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4467267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="668" mass="72414" checksum="5D1BEA654E860E0B" modified="2025-10-08" version="1">MSFLAARNLRFAATRTGPYAGLPRSLIARNMNSKVNGPVVGIDLGTTNSCVSVMQGKDSLVIENAEGVRTTPSVVAFTKHGERLVGLPAKRQAVVNSANTVYAFKRLIGRMYKDQEVQDDMKHWPFKVVAKSDGRPAVEIDNDGKKQQLSAEELSSMVLTKMKETAQQFLNKNVSHAVITVPAYFNDAQRQATKDAGQIAGLDVLRVINEPTAAALAYGLDKNDSSIIAVYDLGGGTFDISILEMQKGVFEVKSTNGDTHLGGEDFDIVLVEHLLNEFKKESGIDLSGDRMAIQRIREAAEKAKIELSSTTQTEINLPFITADASGPKHINTKLLRSQFESLVDPLVKRTTDPCKKALSDAGVKASEINDVILVGGMTRMPRVGETVKSIFGREPSKGVNPDEAVAKGAAIQGGVLAGSVTDILLLDVTPLSLGIETLGGIMTKLINRNTTIPTKKSQVFSTAADGQTAIEVKIYQGEREMVRDNKLLGNFNLVGIPPAPKGVPQIEITFDIDADGIVNVAAKDKATNKDQSMTIASSSGLSDKDIEKMVSDAEQFAESDKARRSLIEEANKADSVCADTEKAMNEFKDQIDATEKEKVAQLITELRELAQKGQNADPSITAETIREKINEAQQASLGLFQKVYEKRNAESSEEKPAEDSEKKEEKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V048</accession>
    <name>A0ABQ8V048_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADP-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_898199</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4467777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="329" mass="35628" checksum="36985209B282998C" modified="2025-10-08" version="1">MTITRRAPDDEDVAIDIKFAGICHSDIHTARNEWGRTTYPQVVGHEIAGVVNAVGKNVTKFKVGDHVGIGCMVNSCRQCANCVDGEEQYCTSGLVLTYNSTDPKDGTITQGGYSQYIVVDQAFVLSVPESIPLDKAAPLMCAGITLYSPLNHWKAGPGKRVGIIGFGGLGHMGVKLAKALGSEVTVFSQTNSKKELGLRFGADDYVATSEPDAFSKLGQRFDIIINTVSAKIPLDLYLSCLRRDGTLIQVGAPEDQLQISPSSLYAHRVGVHGSMIGGIAETQKMLDLCGEKQIFPEIETIPASYINEAYERVMKSDVKFRFVIDVSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V097</accession>
    <name>A0ABQ8V097_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Velvet factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_861402</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000162">
        <property type="protein sequence ID" value="KAJ4463464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="26"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="357"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="513"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="676"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="770"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="806"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="837"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="863"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="921"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1019"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1055"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1089"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1118"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1178"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1202"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4463464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1252" mass="132150" checksum="8EFB7CC7756C1575" modified="2025-10-08" version="1">MSSSSASAVGVIPNAPPVPYPFDSYRDRLEYELTVRQEPKQARMCGVGGKADRRPIDPPPIVQLRVVDPLQPSNSSSNLGGRQIARASSPNAASPSTTMASSPAPSVSTLSRDGSSASDSGNVDREGDSATPTPSAAATSYAQSYLQNPYYFMFACLAKPDDDTELHWLKDGRTRCTTGSVVSSLYHLKDPQHGNEDAGFFVFPDLSVRTEGSYRLKLSLYEVVGSNVRHCRSIFSAPFYVYTAKKFPGMEESTPLSCSLADQGIKIRIRKDIRVRKRPVAALLDPQPMSGRGNNANVSNALAASQHTFGAQSQFSSTPGVSASHFSGSSSATASAPGLNDTGYLTHFPPQLQQHTYASFPLPLPPQTPYQQQYHPLAPPPGSIPAGGPLQPLPPEAQPAWSGSRIAGTSTTAAVEAHSGGRGRRSESPNGTRSDDDDPRSDLGGPSDPATVGGEDVHEGNELGMRMDIDDPLRINENDSDNDDELDEGRPSSSSDGRLTRTGRRRTGSTRESSSKDKDKEERRKSKDSPKLRSKSSSVSNIRRELKRARTDSYQQPQYHQPIAPAPWAPAPHPPFSTSTSSSVSSSSLASGSNPSTIGGPNVPAPVIDPSLNGASIGGLPPGVRIPPPPGAIIAPGAPNKVTGASRSSTPVSLGVNPSIASVSRIPPPPGATIEASSTSLTTAGKGSGSSANNASGSIGITQIDTNIVDTPVQGSESPVGSSAGSSYHHQQLPFEQPHAHQPPMSGPPPPAYSVQAQPPQLAPLPPPHQVNSSQYPSHMSHPSQQTAPHQHPLPPPLPHSHSLPGPTPYNPYRQPPIPSHPQYGYSAPPHATYNAVPPPPPMAPPTPQGYAGYPAWGVNSGQHQQHQQIIPQEQYQQPMSMQQLQYQQPGYSYPLPPPTQVRPYEYGQPLQPQPQTQHMYAPYGPPYGYYDAAQQQPGAPPQQLQQNPFHAGVYGGTVGTPSPSAIGAAPIVSVPPLLRPGQPGHQSTTPPNGAGSGYVDYGSSPFASQPPGLPRPGSPRSFQQAQPQQYGYPSHPPGPPHHPHSQYSQHSQPHPGPPAPYPPPYGYMAYGNGNGNVNSNGSLPTTPGFGGNNGAPGTEAWGGGTGVPPSSGAPTPWDSTPSLSVYPGSATNSQSHVGVQSGNAGDRIQLAPMRQPNSGSELSGMYPIIQLRSSSRSSRDEGKERSGSGSGEGVAKISTTGREKDRGRDRDRDVGQSGRDRERDKERDSRDNERGPKKNPLAIGNIIQGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0B0</accession>
    <name>A0ABQ8V0B0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_906294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="332" mass="38660" checksum="B5EB4BC492127B1E" modified="2025-10-08" version="1">MPPRPYLRLRLSTNSKLECISKYRKTISTRYIGLLQSSGQNCAQNFRQFSSTLDEDAVAAMDISEKTNHNDMPTVDDFSYQSIPRPSRRAQIRTRVIQTAIGYDKKKWYDLRRCVRDNLAAARIDWSVPWRAQNPEQIAPVFTAVEKHFPETRRFADRWAINQIAYQYGIQRNYYRRTERDFKPDLEAEDNVPAGSIPYSIPTYKVPMKDIRQALGYDKKRWNYLRTCVRENFAVEFDWSVPWRAQKPERLARAYSAVRLRGFNILLGLRSPSLMVLIIARLKSTFQKHVASLNGGLSRQSPKCFGMPASVEADSVLAYFTNPFLPLSHFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V292</accession>
    <name>A0ABQ8V292_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_778341</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046031804" evidence="8">
        <location>
            <begin position="23"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="9"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="518"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4468977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="547" mass="59209" checksum="9CEEAC95C469D0CC" modified="2025-10-08" version="1">MPLWQTILVITSCSFAMLTTTASNSAVSIALPTMEDDLEIPQAALDWVVAANPLSNGCLLLLFGRLADLYGRKKVFLLGSFWLVAFTLGCSFAQDALTLDILRGFQGLGSAATIPASLGILAHTFPPGKARAIAFATFAAGAPLGGGTGIVFGGLLTQLTPQSWRSPFYLVSGLTVLSMITAMISFNPDHPSTEEDQRVDWIGAFLVTTGLVLIVFVLGQGEVAPKQWSTPYIIALLIVGVIFVLLFLIWQYHLERVQNTTDSNPYPIFYVVSLSLFALHHLPTPPPIMKMTLWTRARGRVAVVFCIACLNWCCFQGWNYWAILYYQNYVGYSPLRTTVRMVPMFVTGLLCNGFVALFVDHIPMTILVAAGTALTGCSALLFAVIDPNAVYWAFGFPSAIIAVIGADFVFACGTMYVAKKCSPHEQSVGGAVFQTMTQLGTALGVTVSTVVFDRVLESRAADNGIDVSDIGSSGPRWLTLPAYKAAMWSCFAFGMCACLLTVIFLRVGIIGHRVRPSRSPTLTEEVEGQKTVTNSARQSAEKGQIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Q8</accession>
    <name>A0ABQ8V2Q8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_984190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4471184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="40968" checksum="AB6D2FDE7B1B38F9" modified="2025-10-08" version="1">MLATTIPSELKCHIATFCAPAALANLALVHNSFQKESEAILYKQLNICLVSKNTKSRQIWTTLKLHTRKANLVHSLTIWLLPSWESPNHDIRTAYIELFCGALANMHALRELRLYFSHKDMNWQMKIMAVLRKVPFNLNSLHCSQFFDLSAITDAHSNSLQTLGVFSNGGDDSFLSTIQNISVKHPDLTLFSYEQEGAFTMFKILHIYPALSLGSGFSWKPISDCYSRNSNPHMGLETESVISVRIYLSDISDTQSLRRLVEEMIGLFPNVRGLELLFRDTPPELNVKDLSTIISPIPCLQELSFRHWFSSTQYCGQSITNSDRFALARTWEATCSNLQSIEFLDGSWVQRSVDDNLDWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R7</accession>
    <name>A0ABQ8V2R7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_851061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="169"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4471179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="364" mass="40421" checksum="EB738DEB5038F0E0" modified="2025-10-08" version="1">MPPAPPQPPTVIQVYTPFFVGTFLNIFLYGVAVTQMYTYYRTSASDKLWMKLLVLYLFVLDTVNSFCDIGLLFEPLLLDFGNQDVVATSPWTLRLDGISTALISTPVQIFMAWRIKIIMETIIPTVIISILAISSLTGSIWLAIAVSNTPQYAKFDDFRAAPSLWLISSAIADIAIACCLVYGLSKKRTGFAVLNDQIDRIIRVTVQTGSLTALTALIDVIVFLSVPDTTIFFAWDLALSKLYTTTLLSSLNSRASARNADRNKVNEPNALFSSETSSHLTFNQQNARVSRYNPTTQAPKNTNGFSEDHYELSSRPQSPPRRERDRLGFRDPAPPTDFNVLVSRSTISDNPDDAIYPPSKNVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3B0</accession>
    <name>A0ABQ8V3B0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_599020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="340" mass="38366" checksum="AF8A4DD0F8C8DD32" modified="2025-10-08" version="1">MSQRNSAIPQYVREHVEEFERARNLSEPAVYASMLAHRALQDSPSEIPPALTALDARNDPAMRPFDRATNWLRKLPVNPKSFDDVFATHAAHDPTGEADRVPEQWRHHDPVTHMVEIPVLHDYPVQTRDAEHESRSAYVTAMTSLEEGRQHHPHGFTSAVPRPFIPEGRHYPSGEPESTFALKTVPREYANTDYAQSPARYLTPGQPLMNRIGRPLDDGESAYATAISHELFDEQGRLLNHLPAPVQKPQASQERLTALQAMEQFQLQEDREDREQFTPTPRAHFRPEPDQPSYAVEQSLISHAPSQGNQNHLLRKPSFNLQRIPLGPPSGPGIDNASNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3M0</accession>
    <name>A0ABQ8V3M0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="67"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="195" mass="21683" checksum="FE0422E50E08EFAE" modified="2025-10-08" version="1">MYASPLAASLFNLKNFDVSEWATLAPYLAFVTSTPEPISVRFPEDEEDSEDRSNCQFSLAHGAKILLNTATLRLKRDHRYGLCSENGTGKSTAMRAITNWLLSHLRMKSGPSMSSTELTGEEDTSVLTFIPSHKRILANEAEILETLTSVSFADERQKQVIGSLSLSGSWKMKLDLARAVLFKADLLYVMISIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3N5</accession>
    <name>A0ABQ8V3N5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_779294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="22904" checksum="0F67E109023F99E7" modified="2025-10-08" version="1" fragment="single">MYLLVQDPASRLSEDDMYDIRAFNLKLDTNLGSRNFEKLRRSKLVPNLETLHRIQARVSFLSGIKPVSYTCCVNSCICYTWIHEKSDHCPYCNEPRNDSRNRPRNTFQYIPLIPRLVNLFLDSTTIQKMYYRAEYNPEPTGVADVFDGTHYRHLCREFVRVGMERLGHRFFEHVTDIALALSTDGVGPFKSRKKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V427</accession>
    <name>A0ABQ8V427_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pheromone receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_781939</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14966">
        <property type="entry name" value="7tmD_STE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000481">
        <property type="entry name" value="GPCR_Pheromne_B_alpha_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001499">
        <property type="entry name" value="GPCR_STE3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097:SF1">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02076">
        <property type="entry name" value="STE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00899">
        <property type="entry name" value="GPCRSTE3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00901">
        <property type="entry name" value="PHEROMONEBAR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="8 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4465327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="326" mass="36890" checksum="2C92C0A6EAE2A48B" modified="2025-10-08" version="1">MANLDYPLFPIFAFFGFVLPLIPLPWHLQAWNSGTCYFMLWASLACLNQFVNSIIWKGNVINSAPVWCDISIRITMGAIAGLPASSFCIVRRLYGIAAVRNASITRAEKRRAIIIDSLICVLGPMIYIALQYIVQGHRFNIFEDVGCMPALYNTIPLYFITYSWSLIFGLVSAVYCVLSLRAFAQRRLEFAQFISCNKTLTIGRYFRLMALAMTELMCTIPLSVVTIWLTAATTPISPWISLANTHIDFSRVEQFPSVIYEADPKMALGIQVNRWASVVCALIFFGFFGFAEEARRNYAIWGRSILRICGIQSSLHPFSSDKKRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V430</accession>
    <name>A0ABQ8V430_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_906032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="282"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4468093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="40671" checksum="11B7496D7A55C20E" modified="2025-10-08" version="1">MLTVLRRSCRSQPRFFTRGFAEIVPVTSGRGSRPSAPPPLKGTIDPPPTRVIAGPDGSSNALNDEFQVAAPERLGNRIPVRANHGLYAFFRKKDPEAGQTLIGEAQFETLGGSIEMERTRSGRSWKASELRLKSFEDLHALWYILLRERNLLATQEEEVRRLGVMKAVQTFNNQIRMCRKSMARIKYVMNERRLAYEGAVTLAEEEKMAHVTNLVLKQQTAEYRTEREHILGRQKRAKMKAIREAKRVKMQAKTEAQAEMEAQAKTEVQAETETEARTAVVQLDSEQDPVTAQPESVEVRTDTTGESASLEPVETKTDAPEVVQSQQVVEKSEQTTKFRPSQSESASEVATAGLFGTRGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4X6</accession>
    <name>A0ABQ8V4X6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_775023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362:SF309">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="315" mass="36592" checksum="01DB1FE23F22B1D0" modified="2025-10-08" version="1">MSHGIWISDISCPSPTSSESSFDEDEVNYRVKPYWSQYRSILKHRGFHLETVRDVQDYYTFIGMPKRAERLKELEEDILYPDAGLPDNLFRGIRIVDGTKVMVKAVHRESRELDIIRFLSSPAMRRQPMNHCIPVLDLIDVPEDDIAFIVMEQWSSHLVINDAPCCLQLFLSAVRQCIEHCFFMHKHQIAHLDISVRNLLTDHQGHYAYIDFELSRRFDESDARVSGRRGTELPPECGHDAFYDPYKVDVWALAILILRACKLTGFCIPELLELVKPMLYDDPAQRPSMELIMHAFNHMTSSISPQRLLMIPHFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V529</accession>
    <name>A0ABQ8V529_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32691" checksum="EF890F6C2DD2765D" modified="2025-10-08" version="1">MDFPPELERLIFLVAMRTDPSIVPTLKLVAHRVQIWTNEILHEYVLLDDWNRSEGDLKHGLGPVPGKNQLYAGHVSSAFAKNVSSLCLTYNHELSVEQLRFLASCNSLSRLALWVDFSERTELAAVLVSLSLQMLSIEVGHFMRLLRFPSIPHVWTSRLTHLELVFWTADVNLDTLSFAHFPSLQHICFVWGRRTYPSTVKLALESCLCLCTLVILTASGQWADFDKYRNLPEAKGVNIALLPSVRQATYEWVPGGPTVWHRVQEHFNSQRSTPLTTASGQANTLLQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5H5</accession>
    <name>A0ABQ8V5H5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_983538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="963" mass="106142" checksum="B201E5DFB299EFD8" modified="2025-10-08" version="1">MSLWKNFLFVYCGATTISPAHQSLCNNCGEIYLRHSATAPPNQSQGISGDSSQRPPPSQPFSISEAPPTSQVQPQSHTWVHSPATTQGTYASLTPTQTTSSSLMATAIPWSSRRSAGLARQDHQDNRDNAQNHARARLSGVAPSPMGHALPSSSFYASSASSLSLPASSLSSSVFDTVPPSSRIKGGKKSLSHPGKIKAHFRFILSCLPPPTVFLDMEYPPDHTSTLRAPAGTKQHRLVGRAQQLSLTFIMHGDVRKEQLIAPDVNARLVQFMTEQDLIYVERDGSPAVFNEDGLNWTVLYCQHSHRAGGSPILRHHPTPWQLNYWDLIQSAKRYSAVQVGESETELLVFLAPRNKIIAGFLPGQAPCVHRHLCLHFRLWAGFSSANEEDLVNIDNILREACWINRDGEATTGHIPGNCPLHESNLPARILNTVVALQAGGPVSTSGTLLPSMSPESSNINHAVEANRDDSSSSATSTPFSVTSLLPSVSPEPEHQLNAEPEAELQQSLYHSYESIIADAQHFHRISPDVYGPQASVFNALAGTPPHPASARGPNVEAIANAMWDRFIALANGDHSLEESTESQGVTLHNFTMEGLHSNLVLMSIISGDQGAMGRGVWTEVLHLIEHKIIMDDENWQQLGFDGYFTLKLRDFEDIPYPTTDIRHFRAVSLFLRLALMWQVEPVAISPMMVAYLISESMEASISLNLLSRVAPDLNHRISQWPPTAHESISFISVPFQLVSQAFSDNYTVAQLRGLSTQQINALTPKIREAIAFNTRPRQFQVAHPLVKAITEGINITHHHNTSSLYSTVFDSEPEQLQDYLISAWTGRHIQSWQDVVRLFDIQYIESAGREYLARERGFMAGLLRFLQKSVFNCRLFLVAVTGSPYVPVAVSGSPSKFHISFRTYLAHGASASFHSCSKQVDILHSEETSTMFLSSLPDNLEESTLFDSWLLALIGDGDFNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5I3</accession>
    <name>A0ABQ8V5I3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SNF5-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_931891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4466949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="50713" checksum="BE939C4030947E13" modified="2025-10-08" version="1">MQPQTQTQNQIQQTQTQTRYQHVQIPQPQPQQAPVAPVAPVVGTPISSSAQAYFMSYYSQLRTGTTLLVQPTLFPGSTTTTASSSLPIPSTSSLSSTLGTTTHPTHGDHIPDTGALDDDGMDGDFVGGNGRRVGRPSKQQQQVRVDTNMDLDQSYLGLVPPARFIKSRGFLSNAATAQGGPMFSLDYGPNYTFIPPTHPNPILIPVRLKFDVPELGLHIRDVFLWNLHEPSASITPEVFTAQFCRDLDIGVDPYEEIVARQIWAQVEDARGKAWEDLNLDLNQHQDSPSLTQNPNPECRVILSLDMQISTHHLTDHIKWDLLSPLTPEAFSLQLCADLGLSGEAIPLIAHAIHEELCRHRRDVVDWGVLGAHPPLNSILGSVGDSEGTMKDRTGLGLGSLGHGRYPKPLRSTWRDWAEAEEYATRWEVLSPEEVERREVERERAGRRLRRETSKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5N3</accession>
    <name>A0ABQ8V5N3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4470716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="18623" checksum="F7EBC7C66C54865D" modified="2025-10-08" version="1">MSRYNASCTYVDADGTPVEDGVSRVAKAYAQKGKLARRIMRETLGGRKNYQLFICPSVSDARLKEFEQNPQAHGPKIRNTFIDKRGLTTQHLSDWPWNQQVTYIMARNAEEIVKNCKDMRFGDKMDWLALFSERIYRVYLDIIKGRPITLDAGGTKENSQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Q9</accession>
    <name>A0ABQ8V6Q9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_523305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045239170" evidence="1">
        <location>
            <begin position="17"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="158" mass="17292" checksum="844A416A7F225E3F" modified="2025-10-08" version="1">MKSLSLFLMGFSALSAFSNTFIPVTAHPALIRRDLDFDIRIHSGDCDGPEVGKLIPGTFTPTTIERKSGDSAAIDILSALGLPPYSTRKTDASQNSRTFCLVSVKPFPSECSLLTLSDYYTFHYGRDIKESKPIEVLRLKTAKVSCRTPIAPTSPHPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6V9</accession>
    <name>A0ABQ8V6V9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="15664" checksum="32754AE891BE4A81" modified="2025-10-08" version="1">MDAKPRFTHFRARAALPGEDDPAPRQSLSLCQSILGPPPGEVADTPVTPPPTFVQPAWIVPHPNGEDALHACEAIRASRTCTQASNPAESPSFVPPPRNDPVAQFSRASSTARGSLSCPVPKAPLVYPPRHPRTTSWVHQFFRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Z4</accession>
    <name>A0ABQ8V6Z4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_904730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4477614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="205" mass="24142" checksum="9AFC34A70B04F97D" modified="2025-10-08" version="1">MSEQLQTAGKCKHTKFLPLNEPPLRRGVVDRTCFHVTPSYYLGWYIPRDEIFDYYPEAGGKMPAFWTKEVMIPWVKDYDSKYKSNERHCYFRPELSYVTGTKEPHLVVFISSNRTQEFIDMSRNEQFIKDAARIAHIKDFFGEVRWIRRSQLLLFTLLLVSFKDWLSIPQRYAMAAALFGHDPKILQGSRTLLVQLRVVLCSVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7N6</accession>
    <name>A0ABQ8V7N6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TATA box binding protein associated factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_843769</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="6">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4478871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="507" mass="54976" checksum="C409CEE600A4F082" modified="2025-10-08" version="1">MTTKPPKVRSTQPHHTGVYKADSIKDVAELLNINISDAIAIALASDVEYRIHQVVEEAAKFMRHGRRTTMTTSDIEQALRVLNIEPLYGHTPHNPPTFRRAAPTYGHSSTNVASSGSANAGTVYFVEDEEIDFDRVLREEKIVMPKGVSWTAHWLAVEGVQPLIPENPPPVPRDVDINSTETPKTNGVVAAPSAPPLTMINGTGIANNAKKPAQQQQQTQQHLVKQVLSRELQLYYTRLTSSLLPPSSDFAKRTAALASLRSDAGLQALLPYLIRWVGEGVVGALKEGGQTEADGKVLEVLMEVVGSILDNNTLFVEPYLHQLLPPLLSTLLHSSLPRTHSTQLRTISSQTLSGLLTKHSTTYPSLSPRIMKTLLLAMISPGKSRGTREGAIRGLIGVGKEAVRKGLVDSGGAKVVGSEVQGHEMGDWVEDEALTKAVLDALRVLHPPSDSEMKDSLNLNNEADLQVLARLHEVLGEFFAQKVVGDAAWAKAILGENPNDDLPVMVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Q6</accession>
    <name>A0ABQ8V7Q6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubinuclein middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_507690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014840">
        <property type="entry name" value="HRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026947">
        <property type="entry name" value="UBN_middle_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08729">
        <property type="entry name" value="HUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14075">
        <property type="entry name" value="UBN_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hpc2-related" evidence="3">
        <location>
            <begin position="241"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Ubinuclein middle" evidence="4">
        <location>
            <begin position="448"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="588"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4478887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="728" mass="79814" checksum="B83DE1A65600B290" modified="2025-10-08" version="1">MEEQDVTMSSADAEPSPTTIISSDHELDMRRHSPSQQNGQNGVDDPPPSPGAESVSTGAASSDDGDSDEDEDEGAEENERVDENGAIVIDDDDDDDDERGGTSNDIQEPSIIIKDEPSPSNAAPVLLNESKNAPKPNSETANKAENHLPPPTSTATTKPKSKAKAKARSPSPLPIAPLPLQTVRLAIKLGGPDNYTVDISGLAKESGQRPLTPVPKRQDESSDSEIEKAKVAEANQSGSEKPKKKKKNVASEYYDVSDPFIDDSELAVDDRKFFAQTKQQGFYVSSGEVALMKDRSPKKPKSKKHNTEAGPSSQHPRISLEGTKESPIALMDDEDDSSHIYNHQSLENGHAKAGGDRKKKNLHAAGATHSRSPSAAQYGTGLNAPLTGNLAVMRKLNWIDPDPNHGHADGDNEGYGDGGEKVGMKRKRVSYTTVVENGKKRKIVDIASFDPALQANLQRLKEAIAAENWDQKGKFPPSIKPLLAQIAIHAITLDEYDDHFFNLMPSLFPYNKFTMSKLIKRTVFADHLKLLVERQDALLTELKRQADEGFTKAEDEWEKSVVAWDHRQKRLKADHREDSGSTGAPTRHPTEDPDNHGDGFDEDNNPLHPQLMSGTGDPGSAAQKPQSEKDVQPPAKKYRLTENMKAIVWELVLLSNECCRLENEKNTLEGSVMQVSEQGLRKMLYQKIVSSFPPGWMSSGQISRDVSAMKKRLEKELAEEQEMDGTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8Z2</accession>
    <name>A0ABQ8V8Z2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TFIIE alpha subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_848389</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIE alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039997">
        <property type="entry name" value="TFE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017919">
        <property type="entry name" value="TFIIE/TFIIEa_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002853">
        <property type="entry name" value="TFIIE_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021600">
        <property type="entry name" value="TFIIE_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024550">
        <property type="entry name" value="TFIIEa/SarR/Rpc3_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097:SF7">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11521">
        <property type="entry name" value="TFIIE-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02002">
        <property type="entry name" value="TFIIE_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00531">
        <property type="entry name" value="TFIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51344">
        <property type="entry name" value="HTH_TFE_IIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH TFE/IIEalpha-type" evidence="5">
        <location>
            <begin position="10"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4474213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="483" mass="53708" checksum="DB5B37515A8B3176" modified="2025-10-08" version="1">MATTEEQDTLRLLVQHVARGFYEPKYSIIMDQLARHPVLKDDDLAGRMGWQPKELNKVIAVLANDCLVKIYRQNELKEGAQRAVSKQYYYIDYTYFCNVVKWRIAKMRHKIDSNLRNELDNKGYICPQCKATYTPLDVDKLMDFARGCFVCEICQCEVVDNENPETVQGGKDRMSRFNNQMRFIRVGLQKSEAMVLPPFDVAAWVKANLTGGDDKNSDSPGAGLKIAGSDPNRPEDEGVGVVIASDKDEATRKMERDAQAELKRQQNALPSWHLKSTISGDLTALGIKESARAEAAVANGVGSTSNDEVLRGLGVVGMKPSQSTTALVVETKRESKPVTNPDADYYEQYYASLAASAVASAQATPSGSVPGSLDLDDFGEDEEDRKPSLEYLNSLNDYRKRSRSQENEGFSGRNKIAKTESFTNGEHVNVEVGIQGEATPKADPMVYVNGNPVAFSKVTEEDHELMTPEEYTAYFEVMQSLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V901</accession>
    <name>A0ABQ8V901_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_847853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="14009" checksum="B5CE46EFBF093E16" modified="2025-10-08" version="1">MKDIYRTNADTYLDELMWYLVIHHDTVISKSSLHENLRKAGLTRKLLHKIALERDEALRAEYSNMIRTQFSGSGFEFVTVDESSKNDHTLSRRYGYSLCGQPAESEEPFIRGKRYSLAAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V948</accession>
    <name>A0ABQ8V948_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_844566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328">
        <property type="entry name" value="ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="27179" checksum="E32F2B8D3AF997D0" modified="2025-10-08" version="1">MVRSQFHPLQPFFPLETHPNIILTPPRLSDIPKLPDLMNDPGVCVWLTGPPHPYTLEHAEAWVRTTVEEANGILQELKDAEGSDTLKLVGGSLIRCIREIKKDGSDVLIGDVHLRRCESMELAPGVKNNGERLEDSPKLFGLVNMQRENGDPEILWSVGYFLATSHAGQGIMSNAFKAILQQWAIPRMGVRRMIGESYVENYGSRRVMEKNGFVFREILRGHVEAKDQKHDVCVFDLNLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9G6</accession>
    <name>A0ABQ8V9G6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YL1 nuclear protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_550055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="496"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4475145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="595" mass="65977" checksum="EF59EB318B4DEB69" modified="2025-10-08" version="1">MEEDTLVSRRSRRSTAGNRMQAALAEIAVEDLSKEDAEEDKDFIVETYEEDVFESDFESTDEEEPAAAEHEPVENEEKQARKVARSRLERATAAAHARQKVTFNPIATTEGASTSTPASTSKPKRKRRVSLGFTINAQTGEVIAENDQDGDDRNSEANIEGGGDGTVVRRRKRSSKRQTTIKNTTDTVTRYLKSEQQKALQPSRKRSRNNKRPTQAELLARALDTEEGNLVDHRDYLMLEEEKRRTRNKRDQVTISGPLLRWVSKVEEVKIEIVQEKEKEKEGYTANATPGYADNPYLSNLPSTLSSGRGPGYTSQSFLPTPVANPSTSTVPTNSASMTISPTASASSTLIPNSTPSNWPPTTLNSTSYLPQYTLSPTTAVTIPASTTTNPSSTTAQRSQFPQSTQFSAPSGFQLPPTSMPPTAPGSGPMPEPEIKKYRTEKVAKSYLVHELNQDEEDNSKPSWEETMEAMFGNHVKWGGMKVYTVKNRPLTRYIPTCPITGLPAKYLDPRTGVPFANIRAYNTLKKLRREFLLAQSDNAEPKDDKAVDENEDKAGIEDVWDNELGCYIGDFEGNFVLDEMDVGTGTHGDPMVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA23</accession>
    <name>A0ABQ8VA23_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_844567</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF20">
        <property type="entry name" value="HIGH OSMOLARITY SIGNALING PROTEIN SHO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="12">
        <location>
            <begin position="276"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="210"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4477944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="335" mass="34932" checksum="08B3F3232F7A6AB9" modified="2025-10-08" version="1">MPPRGNEGLDFTPILTHYLFLFTSLLAILAWFIAFIGQIIATASRGNGDVGVLWFAIFLQLALILGVLYTLASDSIAMHRFQISVFGAVVIVFAVNGVQAGIFTGIGSLDAMSVGWLILAMVDIVWVLYFTSEEDSLALHIFNSMGTGGLTPPSRRRRTRAQSVHNVTNGYGGYASGGGIGPHDVPYNGKMVSGMGSGTLASPIGMGNTALRGSKSFEPSPDAATRSLGGGSITNVPGGGGPGSSSGGDNGPSSPLMAGAGASAPQATPTDPAVAEYIYKAKALYTYTQSPDDPNEISFNKGELLDIMDTQGKWWQAKKSDGTVGIAPSNYLQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAF2</accession>
    <name>A0ABQ8VAF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PUA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_840435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF27">
        <property type="entry name" value="OS04G0289800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="130"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="299" mass="33108" checksum="9E63F4C9D43B0E47" modified="2025-10-08" version="1">MSAYEKQRLANIAKNKKLLEELGLNKPFFEPVEKPRKPQATAKKRKIEQIEDKDSPRKKSSRTSDASSDHENSTLRRSTRNRGKAIDYSAEIVSEDYIPDSFKVGIRVTKNTGPLGREDGKRVHNPKKFGAIPGIEVGTWWESRQGCSADSIHAPWVAGISGGPEGAYSVALSGGYDDDVDDGHAFTYTGSGGRDLKGTKTAPKNLRTAPQSSDQSFEHSFNASLKKSAETKKPVRVIRGFKSTSNYAPTEGYRYDGLYTVESAWMQKGLNPKGYLVCKYLFKRVPDQPPIPVRMSGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAG7</accession>
    <name>A0ABQ8VAG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ASST-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_448901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF5">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="588" mass="64319" checksum="3A2C41C14E3C3ECA" modified="2025-10-08" version="1">MLFYSTSLIAIFATDNDCAAYYIGLSTRFHELILFLFPPPLLHPMSSVRCSFCSTFIARGLVLCLFLFSVRGDSVLFRSNEYSIGALGYGPFQSYFSANYTPAEWNFVVPVNDSAGAPSLSTGYIFSAPRGASVLRQGAAIYDQTGSLIWDGSIYGQTLSFSVVTYLNEPHIIVWTGTATAAGVGSGYDILLNSNYELVANFTTNLTGETGQTFADFHEAQITSNNTALMTAYQPKSLDLSSIQGPEQGWILDSAMQELNISNEALFTWIASEHVNITECYNTPGTGGGSVAEAFDYFHINSIEKDDVGNYLISSRHCWTMYYLDGTNGDILWKMGGKNSSFSMGNGTEFSWQHHARWVEKNDTYATMTLFDNAGQFGQQQEQMSRGLHLGVDFTNMTVELLTELLPWNQSISQSQGSVQLQPNGNFLVGFGQLPWTGEYSPDGDLLWTTQFGVGDVESYRALRYNWTGTPTDSPSIELVSASKSNLLSAHASWNGATEIVKWELYGASDSSGSSSISLYNKTKDGFETTITVSTVSNSYSHYAVRAIGRSNQVLGTSDFVSSSSALRITGRTALAVLSACTVLLLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAU1</accession>
    <name>A0ABQ8VAU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_461485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4483125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="120" mass="13189" checksum="1E68493B198E3D76" modified="2025-10-08" version="1">MGRDQKIPLRQVLYIVNGTLNIPSTPIFLNTIMKFIVSISTFLLVTLLAITVDAIALDDKLACGAPWNIGHSEGSSCKFWGKDGNGTHVHDGTCHKRSGFHVIHRYECITTSVDLQTTCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAV2</accession>
    <name>A0ABQ8VAV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="190" mass="22205" checksum="7DAB8EC505C6A981" modified="2025-10-08" version="1">MLFFLPNYWVFYFIFSSTYIQWITRLFAVKKKHLSTKEVIENRKGLLPLTASNLILRELSPLDRHRYSLANKEAYDAVSSFNRQAYRIEHILCPYFNEGEIEMFRLIQLKTNAIISGSAALQFFDLTVFDDSDLDLYVVNDWDKVALLTGFLTSIAYDYTPTSASSDPCNRYNSIHFIPIHTLLGWYNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAW8</accession>
    <name>A0ABQ8VAW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_921504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="2">
        <location>
            <begin position="260"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4484582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="482" mass="52601" checksum="17B67C5B8242AED5" modified="2025-10-08" version="1">MRPKNDDRQMSGCFRGFKLRSFVSGKQKQRNENCSTLSASREEDEKVLAPSRDFDFGIPSEWGLSVDQSSFDSSLPPYMTLEDASKSSAAEQTISRVLNELESELHELSMKIHDHPEIAFQERYARDTLTAFMRRHKFHVTSGYLGLETAWRAEYSYGRGGKVIGINSEMDALKGIGHACGHNLIAASGCGIAVALKVALETHDIPGKIILLGTPAEEGGGGKIILLQRGGYDEMDFCLMSHPGPGPLNSFDIGSTTAVLTFEVEYLGKGAHAGAAPWEGINALDAAFLAYSSLSVLRQQMKPTHRSHGIVQGQDWISNVIPDNARLRWQVRAPTYDELVVLAERVRKCFEAAALATGCTVKIDQDSKPPYYDLKNNPILARIFSGIVRTQYGHSVRTNGSAASTDFGNVSYHLPSLHPLYSIPTETHGGNHTPAFTKASATKEAHAANMIATRGLAITGLRVIQDDELFREMKAASACSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAY5</accession>
    <name>A0ABQ8VAY5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_772087</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 16 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="17">
        <location>
            <begin position="32"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4479451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="523" mass="56348" checksum="3552BAA7748C94E9" modified="2025-10-08" version="1" fragment="single">SAPALFEPYVNDTVPAVDEWTLSQSMAADTSRGGLSQLETHYQTFITEQDFAQIAGAGLNYVRIALPFWAIETRGSEPFLEGTAWKYFLKAIQWARKYGIRINLDYHALPGSQNGWNHSGKLGSINMLMGPMGLANAQRSLDHIRIIAEFISQPEYSSVVTMFGITNEPQASAIGNDQVEAFYLQAYEVVRKASGVGAGNGPIVSFHDAFLSRSDWAGFLPGADRISLDSHPYLCFSTQSSAPISSYATTPCTAWGADVNSSMSNFGLTQAGEFSNAVTDCGLWVNGVNQGIRYEGTYVADPSFKSVGSCDSWTDWQAYDQTTKDAIKQFALASMDSLQNWFFWTWKIGNSSVTGKVESPAWSYSLGLEQGWMPTDPRAAYGTCGNTSPWTPPLAANQLGNDKSASLASSVSASYPWPPSTIIGGGVPSKLPTYTPTGAIPTLSAPTFTQSGVTATATPTPGNGWENASDQAGLMVNIATCSYLDPWIGTTVNPPSPLCSSSSKRREPALEYREPMITAMPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB12</accession>
    <name>A0ABQ8VB12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HMG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_769410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040648">
        <property type="entry name" value="HMGXB3_CxC4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18717">
        <property type="entry name" value="CxC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG" evidence="1">
        <location>
            <begin position="31"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="311" mass="36059" checksum="6C385A3D374FA6CE" modified="2025-10-08" version="1" fragment="single">LPPKWCLLESDEPLYPRPLVLRQVQETIYIRNGEGTCACRDGSRRMYSSSLPTFLRECTVYTLSRAIRTNIELQKCSSCERRYIGPETRTLGLFNLNNSLLFTHELLDEYISAFTSSETPFDAWVQQVSRRYQADDNSIPFVGADTFRAAWFAYARLINFEGDKQCERCGEAPENVVWDGVTLAYARKQLRTGLRPPTTVDADSPIRPRTVGKKKEWFEDGVARKRLHHWIAKGGMGWGNDEKDRMAAEERQRDYPGIVESLRCMNKDLAILFEEHLGVKVLERNGKWRPQREYKAFFEMVRLIFLGKIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB99</accession>
    <name>A0ABQ8VB99_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_921458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF1">
        <property type="entry name" value="FH2 DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4485152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="843" mass="91097" checksum="5133EDF924A1E4A6" modified="2025-10-08" version="1">MTAHFKLKLTGGPTRRLSFTDEPTWTLLAERIAGLFDIPAEAIAVAYIDSEDDEVTLSTQEELQDFYQTSYKHGDVVKFTVEDLRIPRRRDRSSPTTPPAPNFRNTFGGSMSEGLPFNIDEDWQHFPSGVGGLFAANGGREDSSVHGFLEEIESGASTISGAQHDETTSISDSDSNVSTVIPPRVDKGKGRAQDNDASSTASLLEEKTFEKPDIHVYNLKGAEPTQTQTHRSRRSSRRSSIAPTMTPKAHVQEVPPPPVSQPPPSIVPSAVSSRPVSVARTNETIAPTSIPVLPSEPELVEAADPPLPALDSTSLEHANPSLSLDVANLLNNLAAIVSTHPELSEGFRNILRNAAAGSYWTAQRDAMSQAANIAKSVTEELSRADQEAGRRVSDALGLLFRTISQTVGTIPTATTGTSSSRIPAPPPPPPPADADDAQWGSGSWGRGGPRGARIMPGYEFMRQFGRGPSSPGIFERPPFGPSPFGPFGGHSMPPPPPPPHGMPRNPRPPPPPPFGPPGGHGMSPPPPPPPDMRGGPPPPPFPPHVRPPSPPDMHGRHGGRPHRFGHGRSYSGGSGYWWGPTGAPRAPSMDAERRDRQTSTELRNQVEAAKLLYKAEKERYRQNRDERRRERDRRMLELMGNLLVFLDLFLLTPSDWEFFFRSLQRAAGETLTHQVPEVPPTPSANPAPVAPPTPLGRDGSRTAHIISNARGSFPQFEMVSVPLPLGPSAGPSAGPRRSNTLPAHPLGRGGHHGNLGRPHGRRHTFEPEDPATRAVNRIQRKLTDMGFSEAAHPDLAAKVREVVPKDGVLTRENEDEIVTNLLEELVIRTTTPAAVPGASGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBK6</accession>
    <name>A0ABQ8VBK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">DEAD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_770471</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17955">
        <property type="entry name" value="DEADc_DDX49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="58"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="294"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="274"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4482709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="475" mass="52359" checksum="515F0D9A70D05A12" modified="2025-10-08" version="1">MTIDRLRIPQRIEVGSKLPKAAPPHSTSFSELGVSLAIQNALKVMSIHTPTEIQAACIPPLLAGVDCIGNAKTGSGKTLAFALPIIQKLSIDPFGIFALVLTPTRELAFQISEQFVILGNSMNVRTAVIVGGMDMMSQALELGNRPHIVIATPGRLVDHLKSGSGEWTLSRVKFLVLDEADRLLSSSFVPELSYLFNALPKDRQTCLFTATLTTSIENVANTAPRPGKEKPFIHRMTEKIDTVATLKQSYILVPSHVRESYLFHFLCNPPESTLHLRRAPSGPTGTKKQKKSKRSQSAEDEAPEQPPPTIIFCARPRTAAYLTLLLKTLSIRSTALHSRLTQRERLSSLSLFRSSVVPVLISTDVGARGLDIEDVAIVINWDLPEEPEEYIHRVGRTARAGKGGIAVSFVTERDEDRVLKIEDRIGVKLDELALSESKILEQLNAVSTAKRLANMELHDSNFGKRERTNRLKTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBN6</accession>
    <name>A0ABQ8VBN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_896403</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046103768" evidence="5">
        <location>
            <begin position="28"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="136"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="449" mass="47304" checksum="720C6767B811D7FA" modified="2025-10-08" version="1">MFNKPSFISSLLLTLALTNSFPGPAFATPAPLIPPTVFESRSSGAGISIPIRKRSGLANSSGVFDVDKARVDVIMTVNKHRRNMMNYLSTQGSLPAGYELEPLLTLPVNLVETLTGPNIIERQTVPLTDENNGELWDGQISIGSNDQKFIIDFDTGSSDLWVPSINCTASTCSSKHKYDPSASSSSEEQDGSFNIQYGDGSTVSGSIYTDGVTIAGISVTGQHFAAVTNLSNSVAQTSFDGILGMGYSTLSNLGAPTFFETAVKQGVVASPEFSFFLSANGSELYLGGTNSQLYTGDIEFHDVNTSPGYWKISGGSVGVPSNASVVSGIDTVVDSGTTLIYGPPNDVKNLWAAVPGAAAYDAEPGFYTYPCNQTLGVSFSWGGKNWSIPDEHMSTGFADGSGQKCVGAIIGQNIFGSSSPTWLVGDTFMKGVYSVFNLGNNQLGFAQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBP1</accession>
    <name>A0ABQ8VBP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF2786 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_921363</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024498">
        <property type="entry name" value="DUF2786"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055592">
        <property type="entry name" value="DUF7168"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10979">
        <property type="entry name" value="DUF2786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23771">
        <property type="entry name" value="DUF7168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2786" evidence="3">
        <location>
            <begin position="74"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7168" evidence="4">
        <location>
            <begin position="156"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4486496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56696" checksum="0E23A62B98AE2C41" modified="2025-10-08" version="1">MARVAIKRRYTEYADTDSSQSETELSDDDFVPTRKSKKVKPSPKPPNEAKVKISAGADMDSIHSLPENIDQTTLERIKKALNLSKHPGTTENEARQAMRLAMKLMAKLNITQAQVLESMEENDDISKQCSGPIVSNEPFFLQLEPFEPVLETASFAVCNMFDVKYYTQVGDESNQIDFIFYGLGPNTVTAAYGFETVYNLIMDWRMANKEAKGINGKNSYCRGVADGFYNFSKKEKRREEKEAEAAEMRRLEAQRKAEEAQRQKEIERLQLETIETKPELDRKVKIEDVKEESADVVDLPSPSFVHESDSDDDFGDDGYDDGDFGYDGNDGGSDFQAGLNTEEALEEDAVAPHFPSKEGVHDIDLDQLLKRSDERARKQAENPDIALNKDKKKKRDIRRVKGDVMEDVKPTTGEANKVPKNKVKETEEPSWQSAGALIAFRQKSLLVAEEYLKKQGLKLHKRGKLAALTLKDANARQSYNKGWEDAKKINLKTKKIKASEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCP4</accession>
    <name>A0ABQ8VCP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF336-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_896774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010371">
        <property type="entry name" value="YBR137W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255:SF1">
        <property type="entry name" value="UPF0303 PROTEIN YBR137W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008757">
        <property type="entry name" value="UCP008757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4481834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18471" checksum="15D296D2A0CD5712" modified="2025-10-08" version="1">MSSLAPPPRDIKTIAEVEKSLIFSSFTADTAWEVGNALRSRLLDFPDPAVINISLANSNQLLFHSVTRSGTQPDNDSWVARKRATVLRWGCSTWYMHNKLKGDEALFAAKYMLGERAGQYAIHGGGFPIRVKGVEGIIGVIVVSGLKQEQDHQVVVETLENYINNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE16</accession>
    <name>A0ABQ8VE16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_386543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045552455" evidence="1">
        <location>
            <begin position="26"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="261" mass="30084" checksum="09EA6A6F7451A138" modified="2025-10-08" version="1">MICFSTAHLFSVFLLLSTFLLGGVGFPLHDPVARGHLQSRDGGEFHIILKYRKPTRNGNQNSQHLPGRDWALTFFPTHSLVIEPQETTGKFVLNVIEFANPRYSTQGTILATVPHRSSLPTLLEDFRKIEAQNWPADCFNLVFEQLKTKKMLEEIPEEWTTLYNRVLKMGAIQLKRELVYEADGGSKTKIIPLYENSVDPREKWTLYIDLLQARSLLNSKEKSWWILFSGRLHILMPCSTRCSVFRWSIITWTGLTLCSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE30</accession>
    <name>A0ABQ8VE30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="290" mass="32851" checksum="C7E47DE19C1C0FD3" modified="2025-10-08" version="1">MTSTSNAFHLRPVSEKRHSSASNSPTASSDSSSPAAEKGNAVTFRETNNPVVLRDLDLDNTLRGKFPNLPAPPTGHDLMAMFPPPAPSLASMPPNRRTEATSGYFQLQERAYFAQAGKEIIRVRVDVDMRDMATDVDERHNTDKRRSRGLDVDMDMAARRRDEEMRLPGPSIPLQSQVSPHLATMRSPRDHREDIEHASPRDIHSKNSVPTHRRMSIDSPLSHSPPNSRYAFSPENEHDHRDLRLAPPEYMSPNSVYPQPDESDEAWRRPMPYAERRRAGKHTRRVVVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE83</accession>
    <name>A0ABQ8VE83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_445136</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="112"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4484619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="376" mass="41915" checksum="F09C70B2313E05E1" modified="2025-10-08" version="1">MALPPKIQLRFSEKLGLNLVLLQIPFLLLYTLLVSRWSKSNKGKPTNRLLFDRTARFVLENLSVRQLPAASPISEETYLKWMSEQKLKPVIDKLILDASLMWVGKEGMNYAMIYCHGGGYIGPLSDFQIEFWHRLQVSLQGQEAGVQLGVAVLDYSLYPAGFPTQLHQLISAITQIISSGLPPSHIFLAGDSAGANIILQLIGHLLHPSSQITEHVEFPQGGHGGFGFAGICLISPWVLSNTESESERINDVFDLLPTKCLTNWKNVYMASVLDPSDQFLVQPNDAVDGWFKNIQGICSSVMITAGGREVLHDSVVKLYENMVLHHPQATLYVQDTGLHCDAMFDIAAKSKNPHPMEQRVFQWFYANILDKKLGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEW6</accession>
    <name>A0ABQ8VEW6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_833314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="10438" checksum="327A7552431E8B53" modified="2025-10-08" version="1">MGVLHVVVRVLASVVGFGVVIVLGASIVIVLGIGVVLGVGIVLGVGVVLGVGVVLGISFVLGVGVGMRAGIGVSVDVWVGARVLSVAVGVGVRVSVGLLILVFSFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEX9</accession>
    <name>A0ABQ8VEX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_765898</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4491839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="139" mass="15429" checksum="1BF3228703D0FC23" modified="2025-10-08" version="1" fragment="single">NGGRNKKGRGHVTFMRCSNCSRCVPKDKAIKRFTVRNMVESAAVRDISEASVYSGESTRDLVCLPINLTGFHFTEYAVPKLYIKIAYCVSCAIHSHVVRVRSREGRRNRAPPPRVRWKDGKKVNPAVAAAEDAKAAAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF33</accession>
    <name>A0ABQ8VF33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_768490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="462" mass="51548" checksum="EDF7BFB8E89126D7" modified="2025-10-08" version="1">MPSSTTSSIPWPSTKPTPSHSSMPRLHHLGWIEYALPDSTIYYSHPTLRVTTDIDLRSITKLDAVTAYLEHRRLHDGAGTPPGFELWLREGLGKTREFVPVRYWVDHKKRLVTTDPIWDAQGDGSGRRHPTGKAVDDSLDMEYRYWAFMEDHPAHVTLPHNARTDAMDILTWCWTDRLLPSQRDLSPPFHQAECQELNNILRSFGDSNGDSGIQAVLHTRLVSRVLMRVVRWRQTNFRPNKALPQDVGNRGRAAPSRQSGFQRSILDIVVFIVFLGIPSLFLPQSNPSSFHRLDEESGLFSSRSAGPILLLGGCACLVAAIILSASVTFLSLPGLDNAARIPGLVAVILATFSIVFSVIALFRYKADMECLSSNVGPWNHFGGEGLTLHSRRIVILSLPLTLLAYSIISFVVGIVLYSFFGVSESPVNILHKHFEEYTRWTVVGVVGALTGVLFTSILFLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFL1</accession>
    <name>A0ABQ8VFL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="182" mass="20026" checksum="7489742D02640DCC" modified="2025-10-08" version="1">MLDGDLFSPFAGTSNPTSNANSLVEFQGSLERLYASYLSNINRLCSPFDSLQPYWEYCGQYWDEPYSSADLGLELPLSTGLTIVFWRAIVSVACSVIMLLLGFAILGTAGDRERNIPHQGQGFLDTARLLKGSTIPELVAVKAQTVKTSRNPEPEILEAVLTHRLRHHSKDDSAGGYLDVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG66</accession>
    <name>A0ABQ8VG66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="21227" checksum="72CE9B7F9FECF690" modified="2025-10-08" version="1">MPISIPDRAVKKRTQFFYEHSTDFPLHRLGLLYNTDGGIDSVPVPVVTQNNDPVRTAAEYVYAEFWIRPAFNVLSTDRAIFDRTSQHTFHCLDGRGIQSSFTVFTESQEIPSTQERRRNTAIQQLLHAGHALRGHVLVVKHCSHGRLLLDVGAWDRLISNDILRQMYDLSTYTPENLPLPPDAGVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG77</accession>
    <name>A0ABQ8VG77_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26773" checksum="534537557799DA45" modified="2025-10-08" version="1">MATIAEILVLLRVYALSGRKQYVLFIAIPLIIVQWALLIYQDVLYKDGTSNLGVLLFARELDTSAVPPLPDIDAYHLCIAIPSTQIVKAGETFLSLFIVYDGLAVSSIIYFVSQQAKGFHLVPILELMQRDGLLYFAVMFSSNFVWLMMALHARPSLGFIQNQPAMIISSIMVNRITMNLQKASEEKMDINGRRTVDDVDISDSILPESDIELGSVHDSYHTNSHRLSGSIYTARHNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGB7</accession>
    <name>A0ABQ8VGB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_769253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38028" checksum="C6A0724B3AC4833C" modified="2025-10-08" version="1" fragment="single">VDEIINHYGKKFHVFASHDPTNPTGRGGVAIVINRRLILVDKPKTYEIIPGRALLLQVTIHKKDKLNILAVYAPNVSGSNGSENAQCWQDVKTYFDTRPNAPKPDIMLGDHNMVEAGLLDQIPAHDDPEEASSALDDLKILLKLRDGWRMTYPNERTFTSMQPASGSQSRIDRIYVTDPLLETAREWKIRESGIPNADHSLASVQITSEEAPRIGKGRWRIPDYVIKDKDFLSYIREQGIKAVQKLRVLTLRTQTNNAQTIWHALKKKVAHKAKERAKWIVPGLTRKLNETQLELDRTLNDIELTEAQKTERAQKLKLEVTGLEQARLQKIQNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGJ9</accession>
    <name>A0ABQ8VGJ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribophorin II</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribophorin-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_868009</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SWP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055374">
        <property type="entry name" value="Ribophorin_II_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23860">
        <property type="entry name" value="Ribophorin_II_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046892749" description="Ribophorin II" evidence="13">
        <location>
            <begin position="17"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II third" evidence="14">
        <location>
            <begin position="35"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="15">
        <location>
            <begin position="173"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4488678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="29842" checksum="AFD8D34E9BDFB173" modified="2025-10-08" version="1">MKAVCFLLLLGAAVQAVKLSVDSVKYSIISAKGEPSTKSLSPTEKSSSEVVTISQDQTLKLSFQVVDKVTGKGVQPEQAFLRFYDEQSGEEGIQPVRVTSSGKAKFDLSLAKPPASLPPTSSAPLKVTLLLGASSYAPAKLELFNLHIPASHPAPTHPDEAKFHILPELAHTFRPDPKLPARVVSALFAGLVLVVPWTILLGLWFSISPRVPRLFSPNILPFTASLGAFEFLLYRYWVDLKLGDVLTYGAVLGIVTVFTGRHALASIADRRLGNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGQ9</accession>
    <name>A0ABQ8VGQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_829934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="19618" checksum="7B262FA3BF45C487" modified="2025-10-08" version="1">MLSPNPVVRLEPHSLYISTTQIFARHGAFHWIIYVTDADGKATTYQWSEQGGTPGLQAEGVDIQELHPVTTYSSTNNLTLAFFKITGFDPATPSDKIHQAALVAFPDRGYPSVRENRQNNLTCRTWALKVLRILMDGGWLVRTDIPEVIEDIVKKRSMEVEGNLESFTESVVVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHT0</accession>
    <name>A0ABQ8VHT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-utilizing chromatin assembly and remodelling N-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_763666</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018501">
        <property type="entry name" value="DDT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013136">
        <property type="entry name" value="WSTF_Acf1_Cbp146"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32075:SF6">
        <property type="entry name" value="ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02791">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10537">
        <property type="entry name" value="WAC_Acf1_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00571">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50827">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51136">
        <property type="entry name" value="WAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WAC" evidence="8">
        <location>
            <begin position="28"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DDT" evidence="7">
        <location>
            <begin position="410"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="561"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="669"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="632"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4494363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="934" mass="106935" checksum="ECFA412EE026CB1A" modified="2025-10-08" version="1">MPTCRRKRVVLTQPSESLLRALKSNPSRDVFYLQQTGEIFETYEAYAARMSFYRLKQFQCEVTGKSGLDYFQALSSERSEAETLHSRFSEPLKPAILKAVQFQVVGRLDHLVESVYERFKDRYYKGEKVLIDLNGIKYYGVVHTVYPPKYSTDVAARDANKPDVDGVEQGTSRPIDNEEPHQIYDDLKTPVKEVNARDDPFLYYYWVLLTELERDKSDKSKGSKPSDGAEMIGSLMEVQCGRMSRDRLSFSKSILRRFIRDCVDRDAAVASPWTVKPAIAQKYGVISSMTEDTRNNVEAIKKGEHDKRKKVWEDKDGPPNKKHKKMTAAQEEKAKAAALKRDREAQEKLDQQRIAREEADRIAAEKKKKKPIRYPTEDLDVRLTDKDLKAGMKLKRPVPTSHALPFNHHSGLFESFLMAWNFMVVYGQPLHISPFTLDEFEHAIKHTDVDMPCSLLAEVHSTLIYNLRTVPFARHSAVLSLLQRKDHLQSDGMEDEEYFGVNTDQLSAAMSDIGNNWERVPLRHSEGREGWEEALIGCLKDHATRENFPRMREILTKLLFAPDPNETPAPHDTSPSSSRAPSPLEPTPPPQRLSAISTPRERYMNLPVHDRIAILSFMVNLAISSKAIHQHMESCEEQLTSLRKEKIEVNRTKKQYLEEMNVLMGEAKEEAVDEDGRMEDPSDMSDVPASDNGSDSGKSKKGTSKSKDLRQKAQLQAHSKQREAARAKQASAKQAMAEHRRLDEEVNKLERRLEAIEREFRKLLGGVRVKPMGKDRFYNRIWWFDGLGSASLVGSGGATQYGAGRVFIQGPSEFDLELMMRRTDDEVPVQIRRLEEEGQEGMLGPGDWAVYSEIDELEQFIAWLNPKGHREIALRQALSKWWIHISAGIRRRMQDLNVHAKLPEARRSARTKIAPDITREPYMMWTNRRAINPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ45</accession>
    <name>A0ABQ8VJ45_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_895247</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF158">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="496" mass="54451" checksum="944418440C4F4085" modified="2025-10-08" version="1">MNFIFYSQLYEKYTNFSTSQNRSIFGKNLRIMDGFWRCQNAFFPTVIAILFAGGIFVFPLLAPALMEHLKLTQPQLSSIALAGMAGQYPFSSIVGKLIDRYGPRVCSFLAAIMFSAAFGLSALEVSLSSARSSLPNTAVAERLTVYFAMAGLGTVLSYFSFLPHYRFWHHNVNVWPISSIFLSYVAGRFFSDTSTGSLDVTRFLLFLAISTGIVHLAGALVLTVPSTTTSPSSSTLETDSISNERSRLLDRGQSPHCTSDPRDSSALELLRDSNFWLLALYMVMILGVCEMIMSNVGTIALSLPAGMARTLVSKGEQAASLQVKILSISNTLSRLLVGPLADFVSPVFSYRLLEGFATIRKHRISRVVFLSGAASLLAASCAWMVFGVRTRHDVWLLSVGTGITYGAVFTVLPGITCSIWGIRNLARNFGIITYSPFVGTTFYSYVYALIVARHSPIGMACQGRICWQSTFYFCLGTSFTALAITAILWRKWSGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJG9</accession>
    <name>A0ABQ8VJG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="409" mass="45546" checksum="7971D12C5D563DCA" modified="2025-10-08" version="1">MGSTFVRMTRSGWSFLEMIDKNDPEDLAVVQLDFAIDMGLLAQQAVDDAEVIEQEGWLMTLPSASVPLATGIIPSEASLFNPEEYVPMKTNPLKRSRTHSPETPSKRFSLTSDLPRPQRSNNRHRRRHRAEGIAKDGHPRGSGKAFERFVLTAEPIRTHLESEELPIAKGGWVAASCSYYGAKVKRELEKMKAQGFTHIPWKGKTPICAVDSEDRVVLVAAGGPNDPSYWEDAAKMSELMLRMGADTQWEVAERHSKRGDFPSVAHGWSYGKGQPMPQRLGGKRQKMMAEFVRNPCVRRVAHYQSASFALWFPKAYGEFQRRNAQLKVKNPEYNENIEGSVYSCCTANCGPNTWTHIHRDTMNATGACCAITSGGPHGPTKGGQLIIWDLKLIFDFPPGSTILLPSALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK41</accession>
    <name>A0ABQ8VK41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_259347</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ELP1/IKA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017233">
        <property type="entry name" value="IKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="8">
        <location>
            <begin position="1"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="9">
        <location>
            <begin position="418"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="11">
        <location>
            <begin position="730"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="11">
        <location>
            <begin position="805"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 TPR" evidence="10">
        <location>
            <begin position="918"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="12">
        <location>
            <begin position="1092"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1175"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1294"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1102"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1177"/>
            <end position="1189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4496761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1328" mass="147864" checksum="A03E0E016F0F2FFE" modified="2025-10-08" version="1">MRNLSLSSVDVVALAEGGICSTAVDLDENVFYIASEKGVSDGATNVEIYRIDKNFVGASLEAITMFSATISGSGTQLISLRVIQDNRSLVAIMRNGDIITTSLDDEIPLMEVQGSVDDGFLAAAWSPDDSLLALITGTNKLILMTLTFDVISEAPLETTEFGQDAPINVGWGSKQTQFHGSLGKTAAQASTSNMLVGCSPDEDNIPRISWRGDGACFAVSSITTAGSHPHRILRVYDHQAVLQSTSESVPGLEHSLSWRPSGNLIASTQRFGFDGGGAGRNGRHDVVFFERNGLRHGDFELRPAHGLVPPPSQALNLRWGHKVKDIKWSSDSNVLAIWIERDHASDLVQLWTTTNYHWYLKQEISAPSDSKFTSMDWHPEIALHLILTTHTQFFLRAYAWEIITSLSKSPIDTGSVAVSDGSDVLLTPFRTQNVPPPMSSMQLALLAGPLDKSQFPRSAARVPVHTCFSPSSDVLGVLWEHGYVEVYHLRTRLGPGRGKVMQPTKIGICSLNETNNHCRQIVILASTCNADSLSFTTLILGSLSESDVVVITQFNGQRITETGAVAMTSRNGRLVRSSTDACVWEAEDGKLFRLNIDNQISTPFSRFSNFCFVAQHVTLSTTELCVGLTGSGKLQVCGGELSCLTLASNATSFAVASGYLIFTTGAHEAVFAPMEDLPTLLMSDNNSKDITSDWEKRRVERGSRIVVCVPSSMSLVLQMPRGNLETINPRPLVLEVVRQDLNAGQYRKAFFSCRKHRIDLNFLVAHDEIAFLEGLGSFVEQVHEVDHLNLFLTSLGQGTSPLSPTTIATISDALREKLEKTDLKTYVNTILTAHVVKAPSDHESALSLLLRLKDEEPALVEDAVKYIIFLVDADKLFDTALGMYDFSLVLMIAQHSQKDPREYLPFLRELRAIGDKNYQKYRIDDLLKRYKSALNNLARAGPSHFDEAIQYIERHSLYQAALSIWSNSDRYEDVLTIYGDWLFERRDFRQAAAVFVEAKRPQKAMVAYEKALEWQELFELALRHSELVSNERIEDMAYRVSEDLVSKKRFAEAARVILDYTSDVKTAVITLVQGNEFSEALRITTLKRESKLIEDVIHPGALESMAQIVEDVTEMKEQLNKQLNRIRELRVKKVEEPDEFYGFEDTALHNVDVMTDVSMAPTAFTRYTVAPSAVSRSSKRSSRSKRKMERKVGSGRKGTVDEEEYLLRSIGKLVGRFSGTRSEGKKLLPHLIRFTAQHREDGLAMQRKLSEFEVELSATVEEIWPTPTDAVGIDGQTQTMQPLQDTWAVRMDDAQRQQKINPTERITKPQVDGDGDEKDWKMKLFDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKZ6</accession>
    <name>A0ABQ8VKZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_760445</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="86"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="178"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="276" mass="29441" checksum="DDB7C3BDC5B0BD73" modified="2025-10-08" version="1">MPPTFVESLIAGGAAGTAVDLLFFPIDTLKTRLQSAQGFTHAGGFKGIYKGIGSVVVGSAPGAAAFFCTYDTMKKTLPFPDHLAPVKHVVSASLGEIAACLIRVPTEVIKTRMQTSSYGTGLSSFAAARILWTNDGLKGFYRGFGITVMREIPFTSLQFPLYELLKLRLSGALGRKPLHAHEAAICGSIAGGFSAAVTTPLDVLKTRVMLDMRDSTLPSPSLLSRFRTIYVEEGTRALFAGVAPRTMWISAGGAVFLGVYEWVAGGLMSSRHDTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL47</accession>
    <name>A0ABQ8VL47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_917752</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045001079" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="20"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="521"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="590"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="629" mass="69991" checksum="FF92F656F37D1716" modified="2025-10-08" version="1">MKVIPLAILALSFAFSTNAFYLPGAAPRNYAQGEQVDLFVNALTPMISGKDDAKLKSLINYDYYNPKFHFCEPDGGPVKQSESLGGILFGDRIFSSPFDIKMLESNQTCQTLCKTTVDGESAKFVNDRIREDYALNWLIDGLPAAEMKIDLRTGELFFDIGFNLGNDDEPFEEMPALNNHYEIVLRYHEYAPGDYRIVGVLVWPYSIGGDQEGAATCDTENISPLVLSETQSQTVRYTYRVTWNASSTPWATRWDNYLKIADPRIHWFSLVNSIVIVVFLLVMVSMILYRSVSRDISRYNASDMSEDVQEDWGWKLVHGEVFRQPSHPMLLGIMSGNGAQLCSMVGVTLVFALLGFLSPSNRGSLATVMMVCFSFFGCIGGYVSSRVYSSLGGSDKRKNAFLTATGLPTIVFMIVFLLNFFLLMANSSGAVPFGTLLVIALLWFGISAPLSAVGSYYGTKHGAIHHPVRVNPIPRQIPPSPKYLRPWSAALLSGILPFGAAFVELYFVMSSLFASKAYYAFGFVALTAGVMGITVATVSILFTYFMLCAEEYRWHWRSFLIGGGNAFWVLAYGLFYWVSRLSLDSFSSVALYMGYLLLLALLDFLVTGTIGFLASYWAVRKLYSAIRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL77</accession>
    <name>A0ABQ8VL77_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mechanosensitive ion channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_228366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016688">
        <property type="entry name" value="MscS-like_plants/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF15">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017209">
        <property type="entry name" value="Memb_At2g17000_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="384"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="669"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4497128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="760" mass="84826" checksum="F44CEA232BB046B4" modified="2025-10-08" version="1">MYPPRRTAPSTQLASGAGGFRNTDGSQDPERAIPGMPQPSLQQHSTSSSWDLLNGIRKFEHSYEEFDSRNASESHLVYAEGDLPKNKFAKMYNYLLNVSIVTRWFLFIVPPLALLWIPGILGLTTFPNATVWGVKLMWWSIWLSVMWGGWWVALAAARILPSIIRSTIGIVAVGTRKYIDWASVLHRYVALFGWMLTMWITWNPLVDTRQESTASDNDKSIVSLIAKLLFGLFLCSAVLLFEKFSIQWIAGKFHEKTYAERIADQKFAVRSLVTLYRNSSDIPGRSDTLKASHLKNSSVNPKKLFKRAIKGVRTAATTTTTALGNVASEIAGSSVLQPNSPQAVVKTALESANKSRLLARRIFYSFTKPGSEYMFIENIARYFPTPDEADSVFALFDRDGNGDASMEEIEIACMDFHREQLSIEHSMQDLDSAVGRLDNIFMSLYVVVAVLIIAVVLDAQFSTLITSVGTLVLGLSWLIGGSLTEVLTSIIFLFIKHPFDVGDRIVVDKVEYTVKEISLLSTTLLDGDGGLVQAPNSTLNDAFIENIRRSPQMSETFSFSVAYKTTFEDLEKLRTKMLEFVQNERRDYLPIFDVAVIDFPEQASMLLSADIKYKSNSQQGAVKAKRRNKWICALKQALADVGIFGPAGNPDATTKPKQYTEVPWEEVKHAEQNKTSRPMRMPAPAGGWRLSENNPSLRDDSDNVFDDDANEQVMQSPGRLPTADSDYASLSTPRMPHAAPMPSQSQLAYAPEAIELSERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLP7</accession>
    <name>A0ABQ8VLP7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_759714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12666" checksum="53D4F89BA1FBAF4B" modified="2025-10-08" version="1" fragment="single">TGDGTHTLLTKARNCDQKRRVPAVLGSIGPLQLSYSPAAHRTVLVMRCASSFRPFYAVNDHWYQVEVEMLRPGTLIPSAKTLSRDTKLLYENGAQQLQRYLLVHCLLLISGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VME4</accession>
    <name>A0ABQ8VME4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7708 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_901450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7708" evidence="2">
        <location>
            <begin position="113"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="545" mass="62775" checksum="7F2D7576EEB6194F" modified="2025-10-08" version="1">MSDSKELTVSAHTSIDDSIVKKYALTKGEWTKLLESETNQRMFHEWLQTQKLDPLETTALACRTFRDVAEFWSDRSTGAESQFKLQHRTGWKLWTKKYQEFSEGALSFMQDLKPLFDIVTSMGIPYVGLATGTVTLLFTFSGKKNAIEEELSSAIEGIRDRLPGLKMYQAIYRENNQLELDLQKKILFAYLAFIELSMEITKYFTQPGYRRWSTAFFNSSKFKDMTIDVYKSLSNIRLRCEELVGLRIDVLVHGMESLKSRNEELHAKIEELQQDRNTAHLLEIQNALGLGSWTPVIHRKMLAEYRTRLFYEHDEEVIYQQMTQKEIEQLQCTIPFADWAKPNFSSILILRGINNENLSQGKIHNWLSPLPLHLISQFHKDGANPQYHATHIFDPADPASRSLFKALPVILLQLLWPHRANLGSNVDGQYETLMAALHDYIACPLSRSDEKAQALGNLAAQVIGFYKGERCPVYIVLDRVDQCSEHYELMSILVNKIIKGAPCPVKVLLVAGSMNWPTQSFFRFDLPVHIQEIVMKQKFLDDNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VME5</accession>
    <name>A0ABQ8VME5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_761527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF4">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632065" evidence="1">
        <location>
            <begin position="22"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="372" mass="41078" checksum="B81223D3D144B1E3" modified="2025-10-08" version="1">MVRTNALALIIGLVGVASVSAHQEPKTDTEIETQRALQRAAYYCAPAVGEFTAARKRAWQQQVLSGLPLNQAAFAPASIPSAGNPSLPTNEDLFNSGAYASGSQTTPQGKQEILACDVIEEETEMQNNSCVLTPIVTEGPYYHNSGHPIRQNIAEYQIGLLTYLDIGVIDVNTCKPLPNVLVDIWQANATGHYAGHPDPAPHLVNEQPQVGGKRSGLLSAFPRTNFHEQWLRGAWQTDSHGVARFTTIFPGYYTGRATHVHAKVFTSWTENPNGTFDGGKLAHVGQFFFEDDLNMQVDKMYPYVENPIRDIRGRTRNWRDSLNIFEDSHGPEGEYNPIFKMNLLGGVINQGLVGFITMGINGSYEMDNWWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMV5</accession>
    <name>A0ABQ8VMV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_820834</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="317"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4497723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="459" mass="51469" checksum="1C7502158050AAD9" modified="2025-10-08" version="1">MHTAGPKSLVKHVVHASYNVTGLSSSYQRATLHGGPRWTGFEAFRRSFRPSVNSLLDPFPLTQNMVAGRVPAYQVRRMWKSQPGQSRPLSPAEEEAGKAAILEKVMKGRQPTDLMLRCTVLDAEGNVKTISGQFKKSDLSVEHQLNPRDLRKIDSRVPNLVPTILIRKEAILVNILHIRALIKADTVVLFDTYGSADSRLHSVYLYHLEHNLKLKGGGLPYEFRALESTLLSVLSALEAEMVFIRTLVGGLLAELEDDIDHDRFKRLLHYSRRLASFHNRAKLVGEALDEVLTQDEDLSAMYLTDKRNGVAHDPLDHEELELLLESFSKQVEEIVNEVENLEANVQSTQEIVELILDSNRNALLALDLQVSIATFGVGTGALITGLLGMNLTNHFESHPYAFLAMTGVAGFVSFMVAFLGFRKLVKMRKVGLSHSTNSPKPRRPWIPLPLRRRSQEGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VND7</accession>
    <name>A0ABQ8VND7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_257577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="574" mass="62921" checksum="CBE230B9E4E5AF9F" modified="2025-10-08" version="1">MMIPQAKPESTTSHSTLKGPSLPPSRQESSDYDWFTSFMQKKHAMTPLESSPLSDYDCVLLSSPSSARSHISVRTPSPSAESQRPIDRSTTIYQPLTAIRPSSGHRSSDSNPESLLEDVERGRRLHGQPVTSRMRSPVPIVLPSPEHTWSPVLIRPPSYTSLDNRLTGLTVTTEQRGASPISRLSTPQSLYESRPSTAMQELPPPNEERTNEASIHSSSVHSSRLPTSILAVRSPSAVYTRSSSGSARSQSPPPVIPVLSNIPSTRTCSPSSIRAWSPPPFGNNVPRPFVYTPVPPSPSQSSMRYHSPRIAPFSNLPAVFTPSSAPELTPRLLGEPSRVIPPMCSGVPSLVSRMHDGTGVGTTKNDHTDSDLNFIPWVPPPITPSVTSTLLHRPHDHTRTGANWGPSQKGGFNPNYHSPWVPLRPPITQTPGVVNASSSPNLHHPSSQFPQVTPYGSWNSPLQPFIPPVIPPPPPDTPKVNGSRWACGPRVVLSGLYPPPSPRQLTHSHLRSIQFHLYHPRCLAFLMCRPRFRQDLSQPVRCLVSLINQRHPMLYLCPPNTLIDITSMMGVFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNH9</accession>
    <name>A0ABQ8VNH9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arylamine N-acetyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_758112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2140.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053710">
        <property type="entry name" value="Arylamine_NAT_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786:SF0">
        <property type="entry name" value="ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="375" mass="42303" checksum="6943D079882BA5C8" modified="2025-10-08" version="1">MQQDGQLRDGLWIKQTPSLYNKTQAANWLSRIKYPGSWSEDNVGDFEADLENLCLLQRLQIVAFAFENTAMHYTNHHSMDISVPALYRRFVVEGKGSYCFGHNTLFLQMIRALGYRAYSGSGRINTAPANSPPNFLSFVHEVLFVQPLKGSNTTYVVDASGGGSCITRPILLKNGAKVMGASPSECHALVKTGRVESSLEHIPNSKEPAGVEWRLIVTHASDSGPTSTRIMYSFIEDEFFDMDYECSNIGIYTGAWAEKESLFMNNIVCARCFWLSDEEMEAELAKNRMLETFECDVYSAGDIPRWDHSLRSRYLGRLGLHANELKRHIGTRTETLKVFHTEVERIAILQEFFGIDIAQADLEHIRGRPPALELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNP6</accession>
    <name>A0ABQ8VNP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_917039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20854" checksum="4F44FA43356E6546" modified="2025-10-08" version="1">MWSKLSLLRHRLEPNEEGPPKPLLIGLRHYLTRIANHKHRRVITKLLCGDYIPHVFRASPSPLRQLSTAERFSRLCRACNLQPETPQHVLLQCPSLNSVSFLRSEFMSDIRQSRPLPINTFLSDSTALHYLKLLIFDWSLIIPTAKFIHDAIGRWQHFLDTGIDLHLEDDVGTGGEDSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP11</accession>
    <name>A0ABQ8VP11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbamoyl phosphate synthase arginine-specific small chain</fullName>
            <ecNumber evidence="3">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Arginine-specific carbamoyl phosphate synthetase, glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_819428</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF7">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbamoyl-phosphate synthase small subunit N-terminal" evidence="13">
        <location>
            <begin position="25"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4498133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="397" mass="43078" checksum="1985C69303B43426" modified="2025-10-08" version="1">MYRKLIYFPRLARGLATTSGPSILPPATLHLKSGQSFLGRSFGAPKSIYGETVFSTSITSYTESMTDPSYRGQILVFTTPLIGNYGVPSNTAPFDAHDVGVVLESQGIQCAAVVVSDVAQRFSHYTAAESLASWCQRHDIPGITGVDTRAITRLLRDQGTTLGRITVGSDTSLPAPKADEFWDPSLENLVDQISTKEPYEINPSGSLKIALLDFGAKANILRSLIRRGAAVTVMPWNYDFNAVRDQYDGLFLSNGPGDPTHCMEAALKLRPTLEEWSKPVFGICMGHQIIGMAAGLDAYRMTFGNRGHNQPVLALVSSGSIKAGRVYVTSQNHQYALKLQDPFPRGWEPFFINCNDSSIEGIKSTADSGRNVWGVQFHPESAGGPLDTIEVSSVLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPC5</accession>
    <name>A0ABQ8VPC5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_166179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF4">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="2">
        <location>
            <begin position="576"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="717" mass="81300" checksum="1C13A50DBE103753" modified="2025-10-08" version="1">MLHSKRALEEESEHLSVKTIKLIHHSNSENQLLETHHGHTCFPTPSEDQKFKSHGSNDHGNMSTERPFTDKQGKMIKPDVVLQELHVMPHIWAESRQEVCESFDWFRSYQGGVYFANNITKGYLLSGFPAKRDGFFHNGKLIISHGGGKAESVQQLKGETKVKHAEDQKAEDKSVRALLTNYRQQIPLVLLIDDRYALFPYNLGGKNITYAVLGVYNITHAWAEYETTKSGQKHVRFKFSFQWCKEQGEPWWHATKDKIVEERATLMPVVSSIEDTIDASPENDNARTSESDYEEAMDISPDDERIPSTTAASPGNAAPKFSRRMPVKKTEFLLSERIPASADRRCMYCDMRSPLVFSVGWGCLNATCTYFWRLPEAGNNPIPDDLTFDEGFLQLQTLIPLDSGFRNINPSQPVTNPQDKITTLQAFTRGMHCIKCGRLSCRSKWEHWECANCQNVLAVNGAPRPVKVLKNLNPGVNFQWYFVGKDTGIMRSPVKPFGDHQTAGNVLTFSFPEGRGQIHHIQHNSMGPLVRLDTLFEEYQTQAADGSLPFRRWPLRSHKLRGSLLTNYFSQNCGVPYHYVGGTANTLTWEEAPTAVVKAKEFIEERTNLALNKQSEFNEVLSAAYMEKQKMSFHTDDEKGLGSVVAGLSLGSPALMHFRRRNVKQGPERKICLSIVLRHGDVLVMDGTGVQQYYEHMVEPINFRIAATARYIDPDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPI3</accession>
    <name>A0ABQ8VPI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RPEL repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_878000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043451">
        <property type="entry name" value="Myocardin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004018">
        <property type="entry name" value="RPEL_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793:SF12">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02755">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00707">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51073">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11023" checksum="F7A78FA197B3D569" modified="2025-10-08" version="1">MTERSNSFDQETVNKLEKRLSQRPEKTDLVDRNILKDDKGIAPSLVAAKEKLQRSQLEDKLGQALQQRPKPEELVKEGILLGERNPLSPCTKLTIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPT1</accession>
    <name>A0ABQ8VPT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_916643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="136" mass="14705" checksum="5FC5D25781E37FEC" modified="2025-10-08" version="1">MAVVVFISRVFPIVRFSILSFVDYVPESCEAVSSLFDLTEAQSFPGHELSKAEYITANSHGITSPIERERSTPTPTSALISAPPLTLLTSPSPSVPVPTAPHHFNVVHSESIRAAAEFELSLCAKFLFGSNMPSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQB8</accession>
    <name>A0ABQ8VQB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_818436</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="91"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="181"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="31887" checksum="C336318A44438857" modified="2025-10-08" version="1">MANFDNSHVTALTALINDAVQDVIAEYAAVGQAIPSLNSLKPGPFQVPAETPARLMKAIKIIEAACAQLTYTVSPPGSVMLNKALEHGEAACLSVVTEARIADLLLDQPAGLPASKLADIAGIHAGKLTRILRLLATKHCFKEVQPGVFANNRLSMKLLSADPTSALVLQRTDDGLLASAYLNKTMSKDDNGIPYQRATGFPYFDFDSQPDGLKRSERFARTMVGWGQIFGKEHFLPQAYPWSVQPPETTICDVAGGNGFATMALLKAHPHLNLVLQDQTQIIDRARELCSSSSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQR5</accession>
    <name>A0ABQ8VQR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isochorismatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_756226</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046654208" evidence="3">
        <location>
            <begin position="20"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Isochorismatase-like" evidence="4">
        <location>
            <begin position="83"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="34957" checksum="105144C681324F14" modified="2025-10-08" version="1">MKFPKSLIALCTVLPQAAWVNCGSHTHTKRLTGVPNDPTIFGNALNFWKKLETGWDLTRGATTNSITLPVPQNGPVVIQPNASALVIIDMQNFFLHESLNGDPEGRAIVPTTITLIHAFRNAGMPVLWTNWGMTDYDIINMPPAFIQGFSSDDTSLTSFGSEMGTVVVPQSDQSIAATSTTPGPNITIDAGRKLTRGSWNAQPWGELFIEQTEGVTNGTDFYFNKNRLSGMWGASTPMQTWLQDNSITTLFHGGVNIDQCVFGTLIDAYYKGYDVIIVDDISATTSPSFATQMVDYNVALDGWRVNSTDILPALVDARRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR46</accession>
    <name>A0ABQ8VR46_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_915965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="44"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="252" mass="27778" checksum="C28389CDACD43A73" modified="2025-10-08" version="1">MYVHYKLPNKPHTSDGHVRSTEVVISSGTKTRAKILSVTVNILSAISNVAIAGTLSIYFQKNKNGFHSTTTILNILILFAINTGAITTSATFPTKSHLNILLMFPLSICAISSLIIVLVAPDTLIYISFFFCIGRVHTISLLATLNARKMILRKSRQDADITTRPTSPLVFQDFGTHNTIKTQHDGVSTRITTNRRTIDSDALCHTIGHRSGLYELQKLSTTNFHSTYMNSTSVVNTNMPALPSNAHFDTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR83</accession>
    <name>A0ABQ8VR83_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_102701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="42397" checksum="3FF73836D6181784" modified="2025-10-08" version="1">MISPLPEFTSNALAADNFVSLPGDDDSEGNSPRSYDRLPVSQITPEEVSSNPPTAPVTPSLLSLTAPRFDEAGQRASRSQSFSSRSVIPTRPASPVVRPIEDNLPVVVPNPLERNSLLRNHLHDLLTDTPPNVSSSLPSTMEHHSSYDKVSNSSHRSSPRRSMPTRSLENSAGSLSPAPIPIPSVQPTTSITIGGSIHSNSNLSQRPALSRASSHAVAMENAQREKRKSEKTLDVSEGLREPGNPESLTLLSVSPNFKASSSPRPQATVPDSDRSRQQPGRRSPPAPRDNEHSSSNPVNRFGTYEPERPPTATSRPIGISHSGKREPSRASKTQDTDVSSSAFVSSSISRSSATSTPFKTGRPSRERDAYQYTSSIGSSGKDKVHLGTMTATAGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRR0</accession>
    <name>A0ABQ8VRR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_817263</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13156">
        <property type="entry name" value="KOW_RPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000915">
        <property type="entry name" value="60S_ribosomal_eL6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049633">
        <property type="entry name" value="Ribosomal_eL6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041997">
        <property type="entry name" value="Ribosomal_eL6_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005568">
        <property type="entry name" value="Ribosomal_uL6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01159">
        <property type="entry name" value="Ribosomal_L6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03868">
        <property type="entry name" value="Ribosomal_L6e_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01170">
        <property type="entry name" value="RIBOSOMAL_L6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 N-terminal" evidence="6">
        <location>
            <begin position="6"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="26269" checksum="4AC2FD754F386BBC" modified="2025-10-08" version="1">MARSKELVPGVGRFSRSQVAAKRGLYKGLKKSEKPAVEPTPETVEKTIGGNNNGEKRIVPTSKAPRFYSAEDVRQPKKSRKTAKPSQLRSSITPGTVLILLAGRFRGKRVVFLKQLESGLLLVSGPYKVNGVPLRRVNQAYVIATSTKVELESIKLSDELNDAYFAKPSSKGAKSAEEEFFEEGKPKEKEAFPASKAALQKEVDSTLITAIKKTENLVKYLRSTWGLSKGQYPHQMAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSA3</accession>
    <name>A0ABQ8VSA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_90045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046498663" evidence="1">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="167" mass="18851" checksum="047090AB29E4E2F5" modified="2025-10-08" version="1">MRFCFDLVSAMVFSFLIVMAAPVDVRSCYCHVSTRINDHLFCSTPKVNAENQKSSNDGPSRIKANGYAPALIRFPWGVTHSEEPHVPEEVFQRVVRYLNDIKTADPSLPLPVFDSLEHAHAHKRVAFYGGSAWPAGHSVKAEFNFGWFNEHDNSMVWVTLPQGSPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSL6</accession>
    <name>A0ABQ8VSL6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription and mRNA export factor SUS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_815441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018783">
        <property type="entry name" value="TF_ENY2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038212">
        <property type="entry name" value="TF_EnY2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10163">
        <property type="entry name" value="EnY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10795" checksum="3EC008F4A620EFDF" modified="2025-10-08" version="1">MSDVDGFYRKIRLRLVESGEWERMKATISPKLNESGWLDDIKHKGVEQAGEMDQLSFQTLFEALSKAGHVGLPLPARRELQAMIRDYLERQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSN2</accession>
    <name>A0ABQ8VSN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_815485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF2">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="573"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="580"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="614"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="628"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="686"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="731"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="752"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="781"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="802"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="842" mass="88834" checksum="DB04960F4164B0A2" modified="2025-10-08" version="1">MSSFPVPPPAPPSLANKVDIVPPPPALPPSSSSTFSSPSTTVPSTLTTSDGGSAPHLEDPLVAPRAQKVDPEIPANMARNLDESLRGVSSPVPASLNNPGGFNIPGVSQSSQAWNPSLPYPNPTPNPNPHRSYYGGYGGPVDAGYGQQQHPQRMVSPSPTISQHITHPPSSSSSSSLTAPLPTIPSLSSSTPTPTSDPAIKVAWSRDVLFLIERAHAIASGSPPGEPINGSVLITDTALLDLANIAIPFILEIASLPPSPSNPYIAESIYHRASLLASGAFPEYTPKNPRSAFRDFETAARAGYGKAWFRIGRDYEGFGDTTHARECFERGVRAGVAGCMYRLGMAHLLGQLSLPLSPSTALPLLHRAALVSTIDTPQPAYVYALLLLGEFTQSQIDPGLFHKLNLLPPSLSHLGPRGLLLDARTHLTTSAFLHFSPAQYKLGHAYEFATPPFEFDALLSVEWYSRASQQGETEADMALSKWFLCGSRIGGPNGSSPPSTSLGGFDKDEQLARIFASKAAHKGLPSAEFAMGYYCEVGIGGSIDLDEALRWYALAQRHGNTDAGERLAALSQPAPQVLSRSEHDEITESKLVRSRTRAKERSEAQMVRDGYLAGQPQPQFQGQGSPGRRRDSRPVVDLIRKNTLGSYQPPQGAHGRYHTEHANTLPPNQVGITISRPPSASAYHQQPPPHQSQVPPLPSSTPNPNPNPNQNQNHNLRPTSRPGGQPGGPNTGQAYPTANRYTLVDPGSGSAPRSNSRSPSTGPGGGRPPPRRGPSGGIVVSGGVSTTSNPTSSNSGPGTPVGAPPPPPPAGAPAPPRPTGPQTFAEMGISGAKAEDEKCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTF9</accession>
    <name>A0ABQ8VTF9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_789005</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 15" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 15" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 14" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="16">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="251"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="300"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="394"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4499256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="504" mass="54981" checksum="1C8B8BE621CFE141" modified="2025-10-08" version="1">MFFCAISGEPPQEPVVSVKSNKVYERRLIVKYINENGTDPITGDKLEESDLIDIKASPETVAPRPPNLTSIPALLQTLHNEYDALVLESFALKQQYNSTRQELSYALYAQDAASRVVARLIRERDAAREALANVQATMGIAPAAPASEDVEMDEDTPSEGLPKEIVARIDETHQALSAVRKKRKAPEGYSTAAEIKTYTAKHTIPSLHSASPSGITSLAVSRSSPNHFLTGGNDKIVQLYDRSTDKVLASLKGHTKKVNQVAFRQKEGEPTLLLSAGADKIAKVWAHDEASDEYIPKLTIRSHKGDVTGLAVHPTSTLLALSSVDKTYSVHDLSTFQQVYRSAPSDEPFTSLSIHPDGTLLALGTSTSTIQIYDVRIGAIAASLTPPDAVPFNIHTLSFSENGFHLAAPSSHSTVAVWDLRKQKASTNIDLGDDFKVNKVVYDVSAQFLGVAGNTGGRVFMYKSWEELVRFEEGGEMNDFVFGDMGKEIWGVTGREVRIWSLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTI7</accession>
    <name>A0ABQ8VTI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactonase, 7-bladed beta-propeller-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_915881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="412" mass="43767" checksum="07F7D1D3FDCD45C6" modified="2025-10-08" version="1">MVNFTILAGGFSVPGFISTYVFNNETNSLSIAAQSFSGDNPSWIAPHPQDPSVLYSVNEIQTIGNLQSFTINNDDSLSLIDTVSTQGIGPTFTNPLSTGEVSAMNFGSPNCSFISTDPSDPLHFIPTNSSGVAFPIPEGGKSNPHMSLEYNDEVLVADLGADKIWRIGKNDPSGNGSFSVQGQIDRDPGSGPRRLAIYNDILFVVSETTSTLTAQRIPAGPNGTTSSLLANISTFPADALPGSKFAAAELLISTPTERFPNPLIYVSNRNIGSTIDPKGDTIAIFEFVNGTTLTLSTPEFNNTATNEKRMKRVSRSSTLRRDNISLESSTSNSEGAGYSFNLLAQVPTGLQQIRSMTLGRVDNGGDAYIVAGATTTGGVSILERVDGGRNLTLLSNNQDVQNRTSFVFLPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU31</accession>
    <name>A0ABQ8VU31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_753330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="242" mass="27407" checksum="33ABB324A7D49D57" modified="2025-10-08" version="1" fragment="single">IPGVIVKGVDFEAQVLELEKIMEKALEDDDWTSLFSNSRHFVKTDIDASGEEVWVTSGGGFERSVLLLLFQKYFEKRFEELCTPLIDCYYTLSTVPMSSTTPISETKRRDLGLFGATVALALVNGYLPEKLNPLLLVYFLSDCQFECLNRTAVMDLIPELKMHNAIAHHMLHNATIGPAEIDHPYFQAFIKGFRLPCKNQYTLPQASSIIAGECVLNYGVIDFTQLRGRFLRICYASIKDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVR2</accession>
    <name>A0ABQ8VVR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">carbamoyl-phosphate synthase (ammonia)</fullName>
            <ecNumber evidence="7">6.3.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ammonium-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Arginine-specific carbamoyl phosphate synthetase, ammonia chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_914474</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="209"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="747"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="14">
        <location>
            <begin position="1012"/>
            <end position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4500424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1165" mass="128080" checksum="ABC4BC37BA03C89C" modified="2025-10-08" version="1">MSFLRPQLTRNWARHCSQPLARGFHKSRVSFGAIAPTNPLRAVAAPAVGSYAPKDGEHVLNSPSELARRISAKVLPKLPRPDVQKVVVVGSGGLSIGQAGEFDYSGSQALKALSEEGVQAVLINPNIATWQTSHQLASEVYFLPITADYVAYVLEKERPDGILLTFGGQSALNVGIALDKMGVLERLGVQVLGTPIKTLEVSEDRDLFVQALKEINIPVAQSTAVSSVNAALAAAETIGYPVILRSAFTLGGLGSGFANTPDELRDLSAKSLSLSPQVLIERSMKGWKELEYEVVRDGADNTIICCNMENFDPLGTHTGDSIVVAPSQTLPDDEYHMLRTAALKVIRHLGVVGECNIQYALNPKSREYCVIEVNARLSRSSALASKATGYPLAYTAAKIALGYTLPELPNAVTKTTTACFEPSLDYIVTKIPKWDLAKFSSQVNRQVGSAMKSVGEVMAIGRTFEESLQKAIRQVDPRWKGFEVYIEPEDLDNALTQPTDMRLFAIAYAMYRKNYTIDQLHDLTKIDKWFLYKVDNIVQTHHTLKAAGSLENIDAELMTRAKRMGFADTQIADLVSSTEDQVRAHRKSFGITPFVKRIDTLAAEFPAHTNYLYTTYNASEHDVDFDEHGTMVLGSGVYRIGSSVEFDWCAVTCARKLRDMGKRTIMINYNPETVSTDFDEADRLYFEELGYERVMDIYELEQAQGVIVSVGGQLPQNIALRLKKTGVNVLGTDPEQIDNAEDRHKFSSVLDSIEVDQPEWTEVTTVAAAKQFADKVGYPVLIRPSYVLSGAAMNVVHQESDLDYRLSAAASVSPLHPVVITKFIDDAQEIDVDAVAHQGKLLVHAVSEHVENAGVHSGDATLVLPPFSLSESDMSRLKVIAEKVASAFKISGPFNMQIIKKSSSADEQAELKVIECNLRASRSFPFVSKVLGRNFVDTATAAIVGQDVPEPVDLMTQKRDYTAIKVSQFSWTRLPGADPFLGVEMASTGEVASFGKDIHEAYWASSLSTTGFKVPSAGSGMLLGGDINKPEMISVAKKLFELGFKLYCSSPVVEEFLNDIPYISAKRIFFPTKDKRKLREVFDEYDIQCVINLAKSRATSFTDEDYVARRNAVDFGLPLLNNARNAQLFVESLARKIPHGGLKGYVEGRIPSEVKSWREFVGSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVX4</accession>
    <name>A0ABQ8VVX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_742788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF14">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="89" mass="9947" checksum="46220B44BBF9DD11" modified="2025-10-08" version="1" fragment="single">IQRLGQHSVVLTADFTDEDQAKNLVEDTTKLLGGLDVVSSLFSNKPLSHSSTATTESWNRIFDVNARGHFFCYKYAAQQMISQRKGGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVY4</accession>
    <name>A0ABQ8VVY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="220" mass="24977" checksum="441C1006EC2B94FF" modified="2025-10-08" version="1">MVMVSALDAFKLYAEQRVTIGIDVVILAWIPLSTFVTVRVLRRCIEDIQAPVLPFWRTGHDSCRASEGLNDLITTFGFGHTFAMFSRLSYAILNYSHSIDVDSDPIAPILFVLCRSSMTTILILSLFAVLIFGLCLELSGIRQNRWGYFLYFYLLVTIPLQRVVTISRWVVALLEGRIRILERDEEELIPFPRLVKGDACASANEQVLSQGRVLSPYRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWV8</accession>
    <name>A0ABQ8VWV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SIT4 phosphatase-associated protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_913938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="541"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="587"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="707"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="878"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1048"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="545"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="558"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="629"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="708"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="893"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="938"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="978"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="999"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1048"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1060"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1101"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1149" mass="126314" checksum="9C2E969FEC379003" modified="2025-10-08" version="1">MFWRFGFHAASSIDTLLDKDDQSLLTLDNLLDEDDLLQECKSQNTRLVDYFQRVDVLGRLLGWVSGEVGAAKFDDEEELLLRGSEMGNKTNRFKYPYIATEVLCSEIWSIVETCVSTHPDKLLVPFWNAVLDKLPEDLRFSTEKNNTHAAAHFAKVNAVFLGKKPGEMLKFIQHQPSVLGRILRHIENPSFVDLLVRIIQLDEYTYGYDGAVGVLEWLSSERLIPRLIDMLSPAYPPDIHQVVSDLIKGIISMATPSPGAGLASNGPAASNTAMSDGGGSGVSSNQFARELAREDSVSKLVAYMLQDFSTSLSESESTLSPDSVRATHFESASSSSIHAMGVLTELIRKNNSDYFEPYLFHTLRNRLIGVQQAMIQQGEGHNGETDGRGTLERAMREMVDRMGVVNLGFVLTILCDDRRLDRLVSYLRRPRSLLAESGTVVPANIPASALTFERFRITELLAELLHCSNMALLNRPLRYVRFVLLNRYQHLYDAEGRLQGGLGGLEELARVISLGNEDEDGDVHRFDGNDDMDTEIEPALELPISSASSTSNASSLLDSDEDEDMSTSSEDDSMDMEEIAMYDEPQMQSTAEPPPISPEVDMHAAEPTESNSVSPSVSADNIGPLRHGSVSSLPTRRNSRRSTLPSASAPSAEAPLVVGERLKKRFLELNVLGVLLDLFFEFPWNNFLHNAVYDILHQILTGQVDTSSHYREDIEKPSTQTDEHDSERRSEGSRGYNRELILSLFRDAQLMHKIVEGQRRNDEESAKPRTPRLGYMGHLTLISEDVLTALDRYPASLRDEIMQYAPKGLDTEHGKGSWDEYVTGRYRETKVRDTRLLGGGKPAVGLSGINSGGRMGDVATKWKVDEEEMGGIQATVGAASSPTLDNKPINNEMRGEFRRSVSSKPRREGSADFGVAPTTLDDDDDDFVAGHSLKRFDNDEDDDGDDEEGWLSQSSTFSAMSERRPLGVNGFDDVFDPQVRKETTKEGLKDPFADDDFGPFTAPTASSSSIPSNSDDPFPSFSSSFTDEMALEGMDNLDDSAFDDNFGDFGDFGEFQTGGTASNSSEPPSLNHPTVDVKGDGEESFDGELTPTAGSWISDLSASEGSLGSISSSIDSISSPEGVNVGLDLTGTGVEASESTEQSAREAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWW0</accession>
    <name>A0ABQ8VWW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ergosterol biosynthesis ERG4/ERG24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_750889</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF52">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE TM7SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01018">
        <property type="entry name" value="STEROL_REDUCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="386"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4500810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="446" mass="50477" checksum="272818842A27AB09" modified="2025-10-08" version="1">MSKLNPRTTHYEFLGPVGTFLISVGVPSMVYGLYYGCSEQTGGCPPPTLTLSKLTSELTALPVTIPLHDISWWQGLWQEVWDTEAALMYLAWYAFCVVAWRVLPGAQVEGTRIRDGNVKKYKINAFSTFLLALGLVTGVIIRFGPEKFTFLYERWVGFATASILMSIVQAFVVYAMSFREGALLALGGNTGNWVYDWYIGRQLNPILSIFGAEFDIKSFNELRPGLILWALIDISMVCEQAVRRGGIGNVTDSMWLVLLFQVGYVADALYNEPAILTTMDITTDGFGFMLSVGDLAWVPFAYSLQARYLAFHPILLGPVATALIVVVNATGYYIFREANGQKNDFRNGKDTRGLKYFTTESGSKLITSGWWGRSRHPNYLGDLLMALAWSLPTGFDTPITYFYVMYFAVLLIHRQRRDDENCEKKYGKDWEKYKKMVPYRIIPYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXT3</accession>
    <name>A0ABQ8VXT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1748-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_806305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF3">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045239196" evidence="1">
        <location>
            <begin position="29"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="74" mass="7862" checksum="8F7D1A5F956DF05C" modified="2025-10-08" version="1">MALGRLFHYAFDAVLVSTVLAGVKKTSGFSLDVDQLTTNPTAKSAAESYLGLGESVYGIIQSTVVNNGYFAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYB5</accession>
    <name>A0ABQ8VYB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_201585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="180" mass="20680" checksum="DC1DAC07FD8AECBF" modified="2025-10-08" version="1">MTNIPAGSKRPLDGAGGSSNSESRDRKRPRDDPKDWRDVHLKTSSRKVSPSNRRDSYDRDRRSHHDAERRRRSREHGKSRRDRDDSRDRRTEPRRLDPSPPRYTSSHDEEKEEGEISPRPSPVMQNSTLPPSLSPEPHPEPETLLEMELDIPPSPPPVEETLASRRAKRQAILAKYANTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYB8</accession>
    <name>A0ABQ8VYB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_873730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22906">
        <property type="entry name" value="HFD_DRAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
        <property type="entry name" value="DR1-ASSOCIATED COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="4">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="217" mass="24192" checksum="74E347C8001BCCD6" modified="2025-10-08" version="1">MKNKNKQTKFPVARIKKIMQKDDDVGKVAQATPIVICEFEQDVRFFHILTVITMFAAKALEMFLALIVEKAGEVTLERGSKKVEAYHLKHAVETIDTFDFLREIVEGVPDPSAGGTIDLDALNAENASKKKRSKGKKAASANGEDGAPAPKKRKKKVKSEEVTEKKANGRGEDAVMADAGEAEPNEEEENEERAQMTDEDEDEDDQWKNDKPYLPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYI1</accession>
    <name>A0ABQ8VYI1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_479823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046103780" evidence="2">
        <location>
            <begin position="29"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="255" mass="26399" checksum="D1CBFCBCCCD6BC6B" modified="2025-10-08" version="1">MQPVRPKMKKIILAGFVACMSLFGSSSGAPVPRHRAAHPAESATASLPASSPLASAPGSSPTTTRSAGANGPTTSSRNPSSSSSSPPPSSSPSSRGSPTASPPRPSSFSLGLNLGQFDYAAAGIARRVSRVFVKRMSAGSSRSMGSARSTQVVQVVQKGGGEEGDRTATTAMTTNLVPVVEAGSASSLNFVDEEEEERRRVPVPIPVLGPRAAGQLDNEGHNTEHTEPGMLRSTKESESEEMVTPDIRACRWGCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZS4</accession>
    <name>A0ABQ8VZS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_16871</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF7">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="16"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="35299" checksum="D9AE2EEF81B86FFC" modified="2025-10-08" version="1">MSLPKTFKAAVINSAGGNFEIVEKTVEAPKAGTILVKVLACGICASDGMVKWGMVPLPRVAGHEIIGDVVAVPSGETRFKVGDRIGSGWHGGHCNNCGSCKENDFITCSSEAINGVTQDGAYAEYVTLRTEAVLPVPKELDPAEAAPLLCAGITTFNALRHVPDLKKGDLVAVLGLGGLGHLGIQYAKQMGYKVVALSQSDAKKELATKLGADIYLDGSKVNQVEELMKLGGAKVILATAPQGDAIVTLLGGLKVGGTMLTVAIADLKFSTVALIGKRASIKGWPSGHAKDSEDAIAFAQKHNIKTIVEKFPLEQVNDAYNKMQSGQVKFRAVLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W081</accession>
    <name>A0ABQ8W081_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">6-phosphogluconate dehydrogenase C-terminal domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_752255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015814">
        <property type="entry name" value="Pgluconate_DH_NAD-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09130">
        <property type="entry name" value="DUF1932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="1">
        <location>
            <begin position="3"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphogluconate dehydrogenase NAD-binding putative C-terminal" evidence="2">
        <location>
            <begin position="203"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="298" mass="31887" checksum="1DAD34F654F51C67" modified="2025-10-08" version="1">MATIAVIAAGAMGSAVGRRLVQGGCTVLTNLDGRSEATRKRAAECGMEEKSLSEIANRASYVLSILPPSNAFSFAEKFLQESKSAERIPNAEPLVFVDCNAVSPATVKRISTLFSQSSPAIGFIDSGIIGGPPQDAYNPTFYASADDKDILLKFGKLSKYGLKISLLEEGAGIGDASALKMSYAGMTKGTTALFTTMILAAHASSPATAEALLHELGDSQPEFLRRITRTIPPMLPKAYRWVGEMQEIGSFVGGGEGAIYEGIATLYQRVEQSLSSDQKDVEVLKKFVEEAKKEMKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B245</accession>
    <name>A0A9W9B245_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_532929</name>
        <name evidence="9" type="ORF">C8R41DRAFT_913928</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000002">
        <property type="protein sequence ID" value="KAJ4494821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9B245"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140824">
        <property type="term" value="F:thioredoxin-dependent peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000010">
        <property type="entry name" value="Glutathione peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 7 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="164" mass="18122" checksum="174AC488FA9F3793" modified="2023-11-08" version="1">MSEKTGFYSLKAEMPGNKTFDFADLEGKVVLIVNTASACGFTPQYKGLQALYDKYKDRNFTIVGFPCNQFGGQEPLDDAGVAEFCTVNHGVTFPLMKKSEVNGDNTNEVYQFLKSQKSGILGLTRIKWNFEKFLIDKQGNVVNRWASTTTPQAIDGDIAKLVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DDJ7</accession>
    <name>A0A9W9DDJ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8J55DRAFT_609858</name>
        <name evidence="17" type="ORF">C8R41DRAFT_128438</name>
    </gene>
    <organism evidence="18 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="18" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000056">
        <property type="protein sequence ID" value="KAJ4464755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DDJ7"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000001">
        <property type="entry name" value="ADP,ATP carrier protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="11"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="115"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="216"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4464392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4464755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="313" mass="33420" checksum="718BE2611D52029A" modified="2023-11-08" version="1">MADKKRSKTPKEFAIDFMMGGVSAAVSKTAAAPIERVKLLVQNQGEMLKQGRLATPYGGVLDAFRRTIADEGVVSLWRGNTANVIRYFPTQALNFAFKDYFKSLFGFKKEAGYWTWFAGNVASGGAAGASSLLFVYSLDYARTRLANDAKSTAKGGGERQFNGLVDVYKKTLASDGIAGLYRGFVPSVVGIIVYRGLYFGVYDSLKPVVLVGALQGSFLASFLLGWSVTIGSGLASYPLDTIRRRMMMTSGSGVNYKSMFDAGSQIIAKEGTASLFKGAGANILRGVAGAGVLSLYDLFQEKVFGKVYAGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY96</accession>
    <name>A0ABQ8UY96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_93976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000122">
        <property type="protein sequence ID" value="KAJ4465738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="397" mass="43746" checksum="F20FE3BD7EF8825E" modified="2025-10-08" version="1">MGRALYSQSYSPAIREPSSSQYEKWSISNPFDPDSEEFFEGAQYEAFLPTPTNSSTNNGESTIPTRVPISATRATMTRDVSQPLRTSRVRISSEDPSVTSASNSLIFDSVPRDFPDMDAPTLPISPPPVTISDFIDADMETTRPTPSPMAADSDSEDPIRILAGFINASRSQGETETNINVSEILRQLDERWRREVREAQNLLQDDNGSRPQRYLPPLSYPSSNASSSYSRADSPSSPIFFPSPPSETLPTPPTMSRELAVFPDSESSRHLTFHLDEDLEQVERELLDFESQSVLDATESLPAPLSESSSAPIVSVSQSQTPPRAVRIRHHPSSSIGNEVGLDMSPPPSVSPRLYNWSRTGSDSRPRYNSLSTSSVSFGRHEGLRSVRGVTISEGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ57</accession>
    <name>A0ABQ8UZ57_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_71811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045950717" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22509" checksum="D3C63C0EAE8E6028" modified="2025-10-08" version="1">MSSFTLFLAFLIVFSSSVIQLHGRPVKSLTTAELLTNAQLAQQLNAAFQSLSSGDACTSGEVACINGEAAECSGTKWKTAACIATQACFAVPSVNKANDAVLRCTSQRSAESIIAASGASGGLTGSNSTSTSTSSNSTSTASSSANSTSFLDFDKYECCCFIQRYVSFLRIQFLGFSKDKHEYYYSIYLYYELDCDHNYFAFRCAQYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ94</accession>
    <name>A0ABQ8UZ94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_67027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="129" mass="13991" checksum="5C2C0C2018A7282A" modified="2025-10-08" version="1">MSSSTRLTFAGMIAGFSLLAKTYPEDGERLGRRKITGIDASATPVETGSRVLRTAKATVETIGLGAGEIEDDGVILDEKDHAGTYGIPDKQTIEAIRHGARMHIQSGIQSLKSRWNDKCGEKRRNSRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0M2</accession>
    <name>A0ABQ8V0M2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pleckstrin homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_925938</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13246">
        <property type="entry name" value="PH_Scd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033511">
        <property type="entry name" value="Cdc24/Scd1_PH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="109"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="632"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="547"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="547"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4466971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1152" mass="126414" checksum="A899BEA55B912ECC" modified="2025-10-08" version="1">MKNSGVGGTWYSRKSPLTIDPHQAQADSNSLYLNPRSAPPLPPNSSKVSLRSLNSVFRQPKINKAPSVFSVESSLSLPDSVASHPYGTMHIAPMPVVSNSDNADDEEDCPVCLEPLSFSFRLPGEKPHIVPECGHALHEACFTAVYGPPPNQSKSTVPRKSNLGVCGVCRRPMKVGDGDGGKSNKLAALTGVGDHTSSVLYPGRDTPTNRRRQQPPKPFDPNEDDPLDHTGSVKSDPSREHSQYIVAPSIQVRPEFSSLTRTHDVNQPLTCIVVIELPGKRVHAPVPGPAPQDYSASRRAEASSHSRQDTSHASPQPRRQQQMSESYSQDMHYNNSSGHGHESLSSGSHKHNEQSAIIQEEDSPFNAITEDLRNRIIDWKGHPLSDLGPLQMYDLLSVRRDSLVREFYVYLFKEALICVVEEKKRSLGRLLSSGLADTASATSSTAQSKGVLRLKGRIYVRHIKQVTASSAAGEMSLTIDMEDELASFILIYKDRGSLEAWRNTIQALVNMFQSQNPSYQQPPQEEARVLEMEEFGGNSKAMRMLSGSTSTTVSSGVDSLLQNGSSRSTMSSSTSHGSVLQQSQRPQMQQKLTTLGEADEMSQYDSPTGLVTPYTSSGPSNSLTPLPHPAMDLIMVISLPPPNSSPSTAQLKLRVIKATLDFIIASLAAKDRLSLVTFEVGPGGRVRKTPFLSVSKGQSKTRLEKFVEDISTRPTSDPDGMGTGRVDEFLVRVSKDEKTDVVTAVNHGLDVVLQRKARNAVSGMVLVSDASDSTRRAQMDLVLARAEAANVPIHSFGYGRSHDPASLWLMSNHTSGTYTFVKDWYDLRDSIAGCVGGMMSIGLLNMKLHMKIVDGNRFRIRKVSGGPSSILASDGQNVDVDVGELRYGERKEMLIELELDNTDLQQRLARANGQGNRLDMRNMNATDRFVQSMGLDSLAIDDVDLADGMMDRMIDEVPVVEVDGSFFDPAAAKNVTRLAHPVLLTVTLLPPTPNAPKPPSSVSDPVIVRRRMELLASDMITRALVLVSRRNFPQAQKIISETKRILHTVLQTISRSLPPPNSGTSRNRKEILTLGAVRAMQAIMQDLQILSEALDDNVDLFAHDQRNFGAQQAMILRDQKSWTGRSATERLFWTTDNSIELVSRSTDWIARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Q8</accession>
    <name>A0ABQ8V0Q8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF1793-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_925416</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032514">
        <property type="entry name" value="GtaA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033433">
        <property type="entry name" value="GtaA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF1">
        <property type="entry name" value="GLUTAMINASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17168">
        <property type="entry name" value="DUF5127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16335">
        <property type="entry name" value="GtaA_6_Hairpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046418852" description="DUF1793-domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="728"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A N-terminal" evidence="5">
        <location>
            <begin position="105"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="4">
        <location>
            <begin position="358"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="826"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4468494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="940" mass="102080" checksum="D25355AC2650CBBE" modified="2025-10-08" version="1">MFSIFLFASYLLLTQCQSIQPAAIPLAVRSPYFQSYLSHTSTTSGINTWPSFWTTNHTLGWSGLLRVDGTLYEWLGAAVEDGGLTIANNATAKAVTLQNYQITPTRSILSLQAGAMDINVTFLSPIEPADLALQSFPFTYIYFEASSTDGNSHSLQVYEDISGGMLEIFFAAMVKFTLSFAEWTSSSTTNIVQWNTTTSNSITYHQAQRSPFQFMTETNDMAEDGTVYHVTNSGSGVTFQTGEDLVVRSRFLNNGSLANSQDTTFREISDNWPVFAFCKDFGTISSTSAPLVWGIGLVRNGNIIYTTTAGNQTRHPYFLTKYADVATAMANFMNDATNALERSKTLDSKIVSDANAISSNYVDLVSLASRQLMAGLEVTVGTDSSGKLNASDILFFMKDTGNSQRTNPVEAMYASFPGILYLNASWAGYLLEPLMQLEQSGLYSQSFAAGDLGTSFPVATGNANPTVFSAMESISDMISMMWAYATFSGDGTLISQYYSTLKTWTDTLISENPLTPNGYITADGLSSANMTNLAIKGILAIRTMAEISKTLGNSDDYNSYSSQASSLVSQWQNIAGSSGHLSSTYGSSNSWAMIYNLYPDKLFGFDFVDDSIYQEQTSWYASEASSALSFGLPFDSNEANTAKSHWTLFTAGTVTDTSTRNSLVSMVHSSAANLKNFAPFPTTYNTSDGTIQGGTASPAQGAMFALLALNLQKQTITSLGSASIKSHVGAIVGGVVGGVAVVALIAIAGFLYRRHRSRRGIREYHSDEKPRGAFAMIFKSKKQRKSLHEPLDEYHIEPVSLGQTYAPNQHTDYSHTSLYPLVHAETVPSTQSPSTEGDTIPYGITYPPIPNPSTNQSRAPLRLRTDNGGDDNAPRSEAAPLPRKTTLTADTRTGSKPASGPSEAGSSDITSDLRGELENLRREMEEMRSRTGYEPPPQYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V108</accession>
    <name>A0ABQ8V108_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_704875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000158">
        <property type="protein sequence ID" value="KAJ4463607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="61" mass="7140" checksum="162301BEBFC240B4" modified="2025-10-08" version="1" fragment="single">GVLESSGDFNLSRVWMTRDADGKLMEIFEGYMSLRVRYCKEYERKGYGEGFNVGFAFWALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1T8</accession>
    <name>A0ABQ8V1T8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="30788" checksum="20F439D251605F6A" modified="2025-10-08" version="1">MSQYRIEKNYGNVRRYKVPDTVVLGLDDMPQKFTLEAYDAARVQIVNTVNQVNTQAQYICEEFQIDRTRPFAIYAFIIAGPYWVLVDYTNNSLSPDFFTTAHSRRNGPYTRSQVPVPVAEDAGMEIDVGVEVPAEEEDAEDVVTTPGFPYGTEPRCLFKMRRLGDDDHDDDSEGDELGEDNDDLDDLNEDEGDEEEEAKSEGEMFNGEFSLDLPLRRYHINPILLMALRRIMGNNHDAFRRRIMGNNHDAFRRRMQNVSWFDCNYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V249</accession>
    <name>A0ABQ8V249_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_853842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000099">
        <property type="protein sequence ID" value="KAJ4468932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045794207" evidence="2">
        <location>
            <begin position="44"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="461" mass="50772" checksum="DB3DEEFAC9F036FD" modified="2025-10-08" version="1" fragment="single">MLSFTRIFLSPSSLSPALHHPLRFLFLFSLAFLINSVITFAEATPVPPGIPQPSEIFQFERCTSHKTSGFLFRVGFYDPQGGRTTKSKFGQGVLVVCIGMNHCLGYMTTTTTAGGGGSVGTVIRTSPQRRNRINGISTDAYHQLPIKPDCDKFNTWSSSYNGQEHNPGRTLVNFLMSIADLQSALRVDPHNTSDTVTIDSETSYILAVLDYLQSRGMLETYNRSQIKEFLETLKNANQLPSSSMLSWGFRNFEGKGRWILLTRVPSEDRKTTLLCFGILYCFGLHDKSGVKYLHPVTSHQIPDKRYLVGMRSSGLYPSFDLQKFEAQLKTSSFLARLTGHSQPAIPFKDISSTEIKLETGLEKEDTEEQGSFYFRVLLGYMAAKGITGNYNTETYGKMMNVLELARARKTNTAVAAALSGGSGSTQQAPAHDTPGTNSQGGGAADYPPKISVSSLLQDVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V298</accession>
    <name>A0ABQ8V298_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">18S rRNA factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_777633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="231" mass="26542" checksum="B063ECFBA88A30D9" modified="2025-10-08" version="1">MGQGMDPQGFAGPKIVKPLTTEALAAYKAAQDRAGVIYISRIPPGMRPSKVRHLMSSHGEVGRVYLQQEDAKRAYLRRKYTSTKKPHFTEGWVEFKNKKVARSVAEMLNAQPIGGKKGTRWRDDVWTMKYLPKFKWNMLTEQVAHEAAIHTAKLRVELSQSRSEQRDYMRNVELARVLEKRSQRKKEQGEEMVLKPLSRTNKRSSEVEGDVARKRRRDNDDGLDTVLGSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2P6</accession>
    <name>A0ABQ8V2P6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_926291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="25247" checksum="35C59EE0266844FF" modified="2025-10-08" version="1">MADFDLKRWCQSITQGQGEVEHFIRQALERVRALERSVDTHHRIAKSFVTMMDDRLLAMNSVLSGCQECIEGKARITASTSGRTAYQLLQPLIRHLEQQASALTDSVQEVKRLAVVVEQRHSTLIRVYAVQKKQDQARIKNAESRLKGKLLDIRKPKIAMAYHKLEGLETKLKAFETDWKLRQVQFQEFEELVDQVQNCSRELMIPVDVELPEQSTNTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V373</accession>
    <name>A0ABQ8V373_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_705504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="67" mass="7842" checksum="7BC08B49075FB7BE" modified="2025-10-08" version="1" fragment="single">LTGVPKRPTKAKSHAGNPPDGYMHCGCELDLVLLEFYYWKTGRIYSPTLEIWETWKNEQMNPRVRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3R9</accession>
    <name>A0ABQ8V3R9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_870650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4471203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="64075" checksum="3D33AB008923CD82" modified="2025-10-08" version="1">MVHPAIGYNDLPLELHHLVAEEITDTQSLLALTFVSQNLHIAYTPELFKSVNKVKGLITLATAQNERYPLRDTHPAAFVRHLDIWIPHEDLGGPEAHRKEVKLTRIVQEHMPRALHNVSLYGGKAILRSLTIDLHIGTTSFAKLIGNIDEGKELFGSLQQLSIRCCFPVNDFRQSLAKLKMALGPSLRSIEFHRPLDDEVDGPTAADPRSFSKFLSQVGERCGNLTRLCIEVPGGQRKLFHDLQAQFDDRAFTFPSLEVFSLADRRSFSQSVEHTRALDITTFIQRHRDIRELAYHCLHEMSFTENQDIVPNLTRFSGYLPEAGKLCKNGRRPLESLVVLIDRRSDEGVERDELYRDLKQTATIRRLIVQDTRHHQLFVGGICSYDIHTIVDACPNLTHLQCTFNQSATATLLESMLVLRNLSELQHLKILAVQGFCGFFKNQHDETLRHADLHRFAESSGRKLTLKIREALNQHQTLQTVLVVVYGWFGQPRPLFERPPIEVRFAFRKSNDGFHIERQIDNKEWDFGSPTCRTAIHQYTQHVAGEAKTFEILQRQRSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V400</accession>
    <name>A0ABQ8V400_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_924185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="44739" checksum="94A5079F52A7AE9D" modified="2025-10-08" version="1">MTFLYSRYLGDKHCYKIPLKYLGKRGPVDDYIEANTWSLAYTRKINTCDYYPIDVPGSPIGYIACPSFASKVKAQLIVLSGQIQSGLITSKSAVLMVQELARRKRRKLADEALFVQLSSILYIAESANFRIDAAVAQDLFEYLDMLNDQFPNLNMSTPSVKNRSRTGSILRVTFSLPKSVKDFGWITLKRWASRMASTIRSVILNVHQDFAEHLLLTYPGVAVAFMTVDQLEACNSYLRNMRTVYPGDRIPEQLVKDIELCLAVYCYFTCKDMMDLVPVPLQVRLDQDGTPSAAYIRNGFCGTPLRRLLDGQWFAKSRAVYERKDGTMATLFTIGFGPSNNPITASECLGDDCERTKTNTIFWSCPLFVVAFESGFIRDVDMEDQDAWRSIMRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V414</accession>
    <name>A0ABQ8V414_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_602565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046110151" evidence="1">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="18569" checksum="D6D4E7053D980E0C" modified="2025-10-08" version="1">MIKLTLLAGLAASLSAVHAQDILGLSYNSTSPYGQSKGIFTLIAGSYGYAMSQAGGSTPTLSAAYDSTTQTLTQVCPYPGLIAAMIPVSGSSPAAYAIEWVNSTVTLPEGSTTTSLYAANEGLDTTLGTKETVWYINGVFKAVTLNGIFEFGWVDEDYSQNGDVTSWIDTTDGSSITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4C7</accession>
    <name>A0ABQ8V4C7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2423 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_849097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019434">
        <property type="entry name" value="DUF2423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219:SF1">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10338">
        <property type="entry name" value="YBL028C_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2423" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4473541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="141" mass="15292" checksum="B730DD67DD02C4CE" modified="2025-10-08" version="1">MAKSLRSKVKRDFRSKKREAGVYAAAEAARLHRLNAKLGAVVSKDKDGDDALEDNIPDAAGVPAAGPSDATNNSADFMQVDDSTRLEDSLSKPISTHGPRGSRREEWRLSKGLPALPSRNGMNRQGGVAARRKAGRSKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4V5</accession>
    <name>A0ABQ8V4V5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_553281</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="45"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4474518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="148" mass="15715" checksum="9555BDDD18737807" modified="2025-10-08" version="1">MAPKPVSTASKAPASTAGKAPAKTEGSKAAKKTASKSKPSSSGPDGEKKKRKKARKETYSSYIYKVLRQVHPDTGISNKAMAILNSFVNDIFERIATEASKLATYSKKSTISSREIQTSVRLILPGELAKHAISEGTKSVTKFSAGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V512</accession>
    <name>A0ABQ8V512_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000116">
        <property type="protein sequence ID" value="KAJ4466333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="27632" checksum="1CB439A60EDA5EFF" modified="2025-10-08" version="1">MALDNEALKVIKLEAQIKNLQEDCEMKLLQIQSLERERNEWMEEKRKLEQKESDIRQMQRAMEDFESRLNKGKCDIEQQDQELKEHEAALKEHKMSLREWETSLWTEEAALARKECEDADALYKRWKQIKDERKRLEEYEADVIRREEKNTKKLEEFHELHLLEARRKFVSLQQQLEKAEKSNADLLVLCETVGNILFMPDMYAREPERMVRAAERLVERCKDVYGSTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Q2</accession>
    <name>A0ABQ8V5Q2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_965065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd17936">
        <property type="entry name" value="EEXXEc_NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041627">
        <property type="entry name" value="AAA_lid_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050773">
        <property type="entry name" value="CbxX/CfxQ_RuBisCO_ESX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392:SF2">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17866">
        <property type="entry name" value="AAA_lid_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="479"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1339"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1618"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1911"/>
            <end position="2043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2135"/>
            <end position="2178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1157"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2219"/>
            <end position="2302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2143"/>
            <end position="2152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2153"/>
            <end position="2172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4475845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2337" mass="261635" checksum="FEA8C06088A0FCED" modified="2025-10-08" version="1">MDRAAKLRKVFEAILRGSLAISPQRSADFLDAITSQEDPATCVSKLISSKAGLSALQDCMRYDLNTSFLNNRGTEVLAYLQDPQLKEIAGGLLIQQVLIKIVDPPIFWSAFVAAFRNGRLGEKGQIAFAGLFLQLLSFSEVDEDHRELAEEDQLMNLLFDSPFPAVRALGAKIKSVLSASTANVVVVSGSFKPGGRHDNDFADFCQIAVLPTASEISCQEEPFLRKSDFLEDLGTLDQRVQMYLDNQFRLLREDMLHEMREEVQIASKQKRGFHRGLIIDGFKLLDMHTGLDDKRSKWAITLQCETDLWIFKKVKPKERKAFLDDNRTRYFRHQTLACLMVDNEIVAFPTLNRDENLLAQKPPILVLQLEGNPIVQALTKLKSAQRHQIRVILIDTAVFAFEPILKAIKEMSEIPLASEILFWDEDSVLKGPRHIEPRLQTLISTLKAHPKDDLRTHLNTSKPITLDESQHSSLLSALTQNLALIQGPPGTGKSFIGALLAKIIHDFSSKNILVVCYTNHALDQFLEDLLDIGIPESHIVRLGGKSTVRTASLTLSSLQKQKLSPKMTRSDWTQVDALKAHASKLHAKLQTEYKRFSSIKIYLGHILGYLELSDDIEEMRFYDALSVPDADNLEEMTHVGKGGKKVGPTYLIEAWVKNRSPGIFADHLRIRSARDIWNMASQTRQDYITRWKNNIVRNAAERIHGLVQQFNTCLAQTDAILMQKDGELVGSRRIVGCTTTAAAKYNEYIRTAEPSILLVEEAGEILESHVVTSLNPKSEQIILIGDHKQLRPKVNDYRLTVEKGEGYDLNMSLFERLVLKGYPHTTLLEQHRMRPEISTLIRELTYPDLVDAPNTQNRLPLRGLQDVIVFVNHTHLEDELDVQDRQDLTATSSKENIYEIEMVLKIVRYLAQQGYRTDEMTVLTPYLGQLQKLRKALAADNDPVLNDLDTHDLVRAGLVPAATADVAKRKIRLATIDNYQGEESDIIITSLTRSNTNHDIGFMSAPERLNVLLSRARNGLIMIGNADTFTNARRGSELWTKFFGLLKRDRHIYEGFPIKCERHPDRMSLLREAIDFDMKTPDGGGTMLKCGLHCCPSKCHQLADHSKMACEAIVQFKCPKNHNQRYKCSEGPLLSCKKCDQEADEVKRKQQRALESQRKQEAQKVEYERKLRELNEQIDSEMEAGRAVEEQKKRQEVLQQKKRDLQEISARNANRLVNSSPISDSMSLLRPLSDLSQTRNTEPFISAASPLPVSVSTLAPSDMPTPLKSPLPTPLDPAAAGLSQAEKEWQRQKDLEGASNEAIDKLMNLTGLEEVKNQVLTIKAKIDLVTRQNASISDERFNICMLGNPGTGKTTVARIYAQFLSSVGILPGNEFIETTGSRIANDGVPGIKAHIEAILNAGGGAIFIDEAYQLVSESSIQGSQVLDFILAEMENNIGKLVFILAGYNKQMEKFFEHNPGLSSRVPYNLNFKDYTDGELLKMLRRLIEKKYQGKMEVEGGLEGLYARIVAQRLGRGRNRAGFGNARALENVFNKVLERQARRINEQRKNGARPNDFLLVREDLIGPEPSGALERSTAWTKLQKLIGLSSVKETAHNLIDMLRTNYLRELKESKPIEVSLNRVFTGSPGTGKTTVAKLYGQVLADLGLLSNGEVVIKNPADFLGAHLGQSEANTKAILVSTVGKVLVIDEAYGLYGGSSQNGSDIYKTAVIDTIVAEVQSVPGEDRCVLLLGYQKQMEEMFQNVNPGLSRRFAIDDPFKFDDFTEDELMEVLDMKLRESDLEASDDAKTVARECLGRARNRPNFGNGGDVENLINKAKMRYQSRQASLPLHQRSADIILQPTDFDPEHDRQSHASANMAKLFEDLVGCDDIVQKLGKYQETAANYKRFGKDARTHIPTCFVFKGPPGLQSRSSSLTLRTGKTTVARKMGQVFYDMGFLSSKEVIECSASDLVGQYVGHTGPKVQKRFQQALGRVLFIDEAYRLGEGRFAHEAVDEIVGLLTKEEFMSKLVVILAGYDDDMNRLMAVNTGLSSRFPETIVFKNMGHMHCLEVLNKALRAEDVVIEDLQQSSRTYLEMASILDQISALPGWGNVRDVMTLAKQMIREAYSDHGTSLPLKLPNDRAIAVMKDMLAERQNRSAIRLSPTKTSAAQNDSTSLSPPFTPSISTSTAPSSAKPEMVPGHKIIQDPVTNTKRDVGVSDSIWHQLQIDQSVAGERAKQIILLERKAKEAKEQEAKEAAQAALLKEQAKTNAHDAAKLMEFKRQQEEMRLRALKVQTECRKLEDELEARKEEEKKEARAQQKLRTLGVCVAGFRWIKQDGGYRCAGGAHFVDNAALGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5S2</accession>
    <name>A0ABQ8V5S2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Tryptophan synthase</fullName>
            <ecNumber evidence="5 13">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_904956</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the TrpB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="5 13"/>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF3">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 13" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="15">
        <location>
            <begin position="352"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="264"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4475865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="703" mass="75958" checksum="E95A3C0B2BC75E77" modified="2025-10-08" version="1">MQALKDVFAKKNAEGTPALVTFITAGYPQKEDTVPLLLAMQQGGADIIELGIPFSDPIADGPVIQESNTIALKNDTDYPTVLGQLREARSKGLTLPVLLMGYYNPILAYGEDKAIQDASEAEANGFIMVDLPPEEALTFREKCAKVQLSYVPLIAPSTTLHRIKFLASIADTFIYIVSKMGTTGSSDKIAMNIALPDIISRVREYATVPVAVGFGVANRGHFDYVADSGADGVVIGSRIVTVIKDAPPGQGNQKVAEYLSQISHKGEPATSRSPPPPRLSTPTLNVNKNGPPIANTTADPTVLPARFGQFGGQYVPEAIVDCLAELEEAHKSAMADPEFWKEFRGLYGYMNRPSELYLAENLTKDAGGANIWLKREDLNHTGSHKINNAIGQILLAKRIGKTRIIAETGAGQHGVATATVCARFGLECIIYMGSEDVRRQALNVFRIEMLGGKVIPVHSGSCTLKDAVNEAFRDWVTNLATTHYLVGSAIGPHPFPTIVRDFQKVISQEIKEQLHAKRGKLPEAVVACVGGGSNAIGTFYNFIEDKNVRLIGVEAGGEGLDGDRHSATLSKGQPGVLHGVRTYIMQSPAGQIIETHSISAGLDYPGVGPEHSWLKDSGRAEYIVATDEEALRGFRILTQREGIIPALESSHAIWGAMQLAKTLPKDTDIVVCLSGRGDKDVEQISQLLPKWADKLDWHIEARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Z9</accession>
    <name>A0ABQ8V5Z9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_924253</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="15"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="154"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="389"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="653"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="748"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="866"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="658"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="766"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="866"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="901"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="917"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="947"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="977"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="993"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4472718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1037" mass="114847" checksum="17169D7A0B873300" modified="2025-10-08" version="1">MPRPGQPPPSTLRNRNRITNKTRLKIIHGDIDVDQIIPDEDEEKNRLLQSVAGVDQEDANEHHLQAVLSQAASQAASGKATKDDEQLAAFIPIPEHSGFAENYTSLYPADRWKDPVSYIQSSSVIDEYTAAALADGCTYYMDERDKEWLDRNNEEARGEGTSAQGSVLTSSGRVSGRSAKGKGKESEDAQPSLMSEDELELVMGLFEKITQEKTEFLHHSLESGQMHFPEFSEYQEVLSLPLPPATFASYSPPTWLPQPSHLLRLARVVYPYWKERCLERAGRRIIPPLNFDESDTLNESYVCFRRRETKAVRKTRASQATSSDKLTRLQNEFEYPLQLATQLLAREQLKRDSARQSHHVWNLRMKMVDLKIKNPTFGDKIDEELLIDKERPTKKAEPSSRVRLPAKSEASAQPSASAREIIRPKERFASYQGKIEQMLQIRKDQDMQWEDHVDIGYVQPTITPYGSRLFKYISAPSELGQPSHDANAAAGVVPKRSIRLRYGRGGRTFIDRRPHSSQGNFKRCRRIMISDDDEDAMEVDDVDPHEEADRRLSERWRFDADDGPPYGPNGAEEQDRVLVDDFDSKFISNLLDQSDLTTLMTDFSIPVIKDGKRESYTPYRLGMTPPMMPIAPRTLLQPQVPVQGVTPVSQQVHAHQSIPISQQLKLPSSVSTQQARASGSNQPTVSQPPTALSTVQSSSRPSAVIPSPQVIHNGRPAMNMPRVDMMKLAFNHSLPSALQSKIEPISQSDVGNHTKSQPEEQHQLVRSKSQQQQVAQSSQPDQSQVQISTTTAVNGLHPTYAALANANPSAYNISHYMPHYPANPVSSGLNNQQLQHLKSVFNSANAGGSQNYNSALFTQMQMPKNSSAVANGTSGTPAVNGSSNIHNFTAPPGRPMQRVQSGSTVNGSSSSPPRPASTVNGIQHDPSASPSPRMMHALIPGEHIPARTSSANGSRTGFRSNGMQNGAQIVYGPNSIQQQQMLQMHSQSPPQPVYNSPQAYSLSPSPPKMQPVSMPSAGSPLLQQQQQQVVGNSQGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V639</accession>
    <name>A0ABQ8V639_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_851993</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="3">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4470529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="353" mass="38948" checksum="F96AA3E01297A01F" modified="2025-10-08" version="1">MASKAVTHYLQFDIQWASIDYALTFPMEIQYLWTSKFRFSTFLYILCRYALLANVLYLLDIAGKLTENCNTWYQFIGALSVLGRAAVIVVFAGRTWAVWGQNRIVLVYMSILGAACVALDITHVPGLRCTGGSTSDLLSILMVVFEYSSAILNSIRCIQAFRAHGKSFEEQKAGFQFLLFEQGNDSIVSLFTTAAVILNFSGFFQRLLNALTLPLSGLLTARFLLHMREWEYKNSPGAMSIHGIQNGGPEGQFNTTFSFRAASVALSTIITSDFGSDPVARGPNPKNSRNRSTGASQSEGLDSIPSTPSTTSHSRADVESQPHPEPTMKSESSTESVKEGKKRVQYAELEKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6X3</accession>
    <name>A0ABQ8V6X3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_705250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="135" mass="15430" checksum="E52F6FA0C3DB2DBB" modified="2025-10-08" version="1" fragment="single">KVSTNLPEHAPVNAKSIGAPHDPDREEDDVPTRESHRGRDRECERQRANMSRLISCNSAHSFWGYVREWTDAKKRPVRVTASQLHDVFKARLNPLPDPPQHFDNNIRQLNAALSDSIPRTTLDHTNGQFFSRPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7R3</accession>
    <name>A0ABQ8V7R3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8R41DRAFT_849773</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20 9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="14">
        <location>
            <begin position="49"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="13">
        <location>
            <begin position="227"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="491"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="590"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="678"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="11">
        <location>
            <begin position="755"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="1129"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="916"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4472646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1228" mass="139375" checksum="FBCE2765E680B050" modified="2025-10-08" version="1">MSQEIDGTQDPYAFDDPNFGMDDEEDDQYSEITQEDCWTVISSFFEQKGLVRQQLDSFDEFVQNTMQELVDENADLILDQQDQHSGREGDMTRRYEIRFGQIYLSRPTVTEADGSVVPVFPQEARLRNLTYSAPLYIEMKKKVMVGREDPDGVPGDMAWETENDDGPESSTKVWIGKVPIMLRSTFCILRGLADQDLYDLNECPYDSGGYFIINGSEKVLIAQERMATNHVYVFAKAQPSPINFLAEIRSAVEKGGKTISQFQVKMFHRGQERAMGNVMKATIPYIKVDIPIWVVFRGLGVISDRDILEHICYDMQDAQMLEMLKPCIDEGFVIQDREVALDFIGNRGTTTGLSREKRIRYAQEILQKEMLPHVSMAEGSESKKAFFFGYMIHRLLLAALERRELDDRDHFGKKRLDLAGPLLANLFRMLFRKLTKDVYRYMQKCVETHKEFNLALAVKHQTITNGLKYSLATGNWGDQKKSMSSKAGVSQVLNRYTYASTLSHLRRCNTPLGREGKIAKPRQLHNTHWGMVCPAETPEGQACGLVKNLALMSCISVGSYSAPVIEFLEEWGLESLEENAHSSTPTMTKVFVNGVWMGVHREPANLVKTIRKLRRKDDISPEVSVVRDIRERELRLYTDAGRVCRPLFIVENQQLVLQKKHIKWLLNGQNDEGSEFKWEHLVKNGIVELLDAEEEETVMISMTPEDLENSRLQQQGIDPHENDGEFDPAARLKAGISAHTWTHCEIHPSMILGICASIIPFPDHNQSPRNTYQSAMGKQAMGIYLTNFLIRMDTMANILYYPQKPLATTRSMEYLKFRELPAGQNAIVAILCYSGYNQEDSVIMNQSSIDRGLFRSIYYRSYMDLEKKSGVQQLEEFEKPTRDNTLRMKHGTYDKLEDDGLIAPGTGVRGEDIIIGKTAPIPPDSEELGQRTRTHTRRDVSTPLKSTESGIVDQVLITTNSEGQKFVKIRVRSTRIPQIGDKFASRHGQKGTIGITYRQEDMPFTAEGIVPDIVINPHAIPSRMTIGHLVECLLSKVATLIGNEGDATPFTDLTVESVSMFLKQKGYQSRGLEVMFHGHTGRKLQAQVYLGPTYYQRLKHMVDDKIHSRARGPVQILTRQPVEGRSRDGGLRFGEMERDCMISHGIAGFLKERLFEASDAYRVHVCEICGLTAIANLKKQSFECRACKNKTAVSQLYIPYAAKLLFQELQSMNIAARLYTVSSGRIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7T1</accession>
    <name>A0ABQ8V7T1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_576545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="201" mass="21828" checksum="2498458D006D8297" modified="2025-10-08" version="1">MPAPEVTVTSNYPHPIVKHVNLMVDTYLANATVEDLRCAVRGLLASGTSGTASQFSAAARKHLCESGALLAPRPESLFDKDVKSGEIIPTHTLKEVIARARTVYGVGMGFASLEILIPIVEATRGAKWKRDGSTAEILTEVDADIVQAIQSCKEELVSDRLKERGGARQIVSKLQYAIQNCSGEEVLAFEKAAHSIQHWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8I3</accession>
    <name>A0ABQ8V8I3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="12">3.2.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Galacturan 1,4-alpha-galacturonidase C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Poly(1,4-alpha-D-galacturonide)galacturonohydrolase C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_969212</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4470986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF11">
        <property type="entry name" value="EXOPOLYGALACTURONASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045317477" description="galacturonan 1,4-alpha-galacturonidase" evidence="18">
        <location>
            <begin position="27"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4470986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="47050" checksum="3C6F0F539E253EA0" modified="2025-10-08" version="1">MHRAFLSSLFLSYGLLFLQNTLPVVSWSTFIVSHTAGQDDTPALTAAMANYSSNSTILFQKGITYNIFTPIKFPTLTNVEILIEGNLTYPTNITAIQGAYSGAWFDFTGGTNVTLQGSTDPNWGWIDGHGQAWWNINQQTNRPHGWAFSHITNGVIRDLKLWKPIGWNFATSGSNNVHIYNNIILAVSDNSSAFPFNTIAYTILLAFSAGGSNLLFENNHVENGDDCITVGSGAINITVKNSYCANGHGLSIGSLGEDGAVADVENVLFENIVMANCLYGARFKSWTGGNGVARNITWKNIAFYNVPFPIYVTQNYWDQEDGPKPNSTTLNNTHIEDFLFENFVGTVRDVPYVEGSCVTDPCWYAVTNATGKEVIILDLYPNTTSNILAKDIFAKTETGARVAAMCDPTTISNDVGFVCQDGPFIPTKAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8P8</accession>
    <name>A0ABQ8V8P8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_527443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037508">
        <property type="entry name" value="Msb1/Mug8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28093">
        <property type="entry name" value="MORPHOGENESIS-RELATED PROTEIN MSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28093:SF1">
        <property type="entry name" value="MORPHOGENESIS-RELATED PROTEIN MSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="743"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="997" mass="107350" checksum="A40F3E2A4B3B1088" modified="2025-10-08" version="1">MPNISLSPKPSDIFKTLSTVGGRNILNTPHNSSTYTLFDTLNTLANRQSPMSFLFSRSNSHSSPSDTDFSPYPPYTTHTLLTLLNSLPTDESGSFVGTVLPSQSSDSPSSHGATGNAYGYLSSYSTLVLGLPDLRELVQLISEHLDVETPFVFSNGGSTVSQGGRGVPVAIDLDAGRVKRLIDKYVEYLTSKSGRNTNLRKSGDHIAGFDDEARFAGPHELGMLLRWGLARVVRIESSSLPHSTTTPQKPATPHTRTLTRGLIPYLAYLNWAKQEHLLSYPLTHFSGLLDTRTRISVPVKVVDEFGAEETLWRDEYKEVIPAALKETLITLFALLAKLVAHSAKSGATPPGLSPLFGPLLFGLGALPGDLISLSPSSASPTVPPPSAIPSSSTSTTPDPTSFESTYTAYLRSVHATEHCLLSFIRWQDTPTSLGGGGSGAGGIPGRLKEWIKDYPRTLSGHARVLAIADLLGSGGFRDREQHSLGPRKGAQTIRVLAVRRTVPVYDRDLVRSSARWGLPTYAAVGGGGLSNNSLPGNKEWGRVSPPVQVPPGNIISNGGGRDKAKGGKMPVRYSDNYRKKMNIPPGVEPGSSPYAPPLSSLSSSSSSYSSYSSYSYASTSSPLTRSTSSTSTYSFQGSSPPTSSSPTSPSTSHHSSQSSRFKTLSDAHWGQFESSGFLSPPSSSARGSRDIESALKFDLTESARKARTAKRGIRDSVDWGDFVNGGFDLSEQRRSGGVSPVALSSSTNSSHLNNNGYGYGAGDDPDKSYVGADGRLTDVGEFALDTGLDAALQFNLSEFGIIGSGKDRDKDGKEGKEVRGERERTITGVSLGKRLKKKEKPLPPFTYDSTPLLLPGSETLIEAAFVDVWTDLVSWGFAELGMGSISQQGLGLLGDLVTGLWNSMAQSNSNPYPPPIHIRLLHQTIKTLEHLLLSSFLKNMSHANTVPSSDISWQEYILHTSLILSMVTIHLMCSTFRVRLPFRLHLPYLRGRIPKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9I5</accession>
    <name>A0ABQ8V9I5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphatidic acid phosphatase type 2/haloperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_982555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF35">
        <property type="entry name" value="RE23632P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="164"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4482630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="444" mass="49825" checksum="31F0C444199DEF4C" modified="2025-10-08" version="1">MPISLKTRLFLSYAVDWYGFSPTVSAKPVSSAQGSKAGWRQPKQSREHAASTAVYCCPILLPLASMQVLQTMSFQHVWFFFNKLHLNRTILIVVALFAHFYLNRLQQFPEFDLTDTSIQYSIKEVQTVSNGLLVAVLVIPYLSIVAGNLLFNFRDWWDLHASLLGLSISYSASGSFVQFVRVTAGRPRPDFIARCDPAAGSVNSAFFGLTNITICQSTDSAFIKDGMRSFFSGHAILSAAGLGFMSLYWAGKLHLFNQKAYTYKVWLVFSPLILSIWICLTRVADRRHHWNDVALGFFLGLLFTYIIYRQFYPSLGDPECDIPFRPRVMSAEPEDTRGGSTGLRLPTRRPGWMRLGGSANRGPEGELESLGFMTTPFDSRHDSRERRRELSSEPKDLNTSNNIVKSSFITLDESLYAVSKPLSILAYRAVDFAAVASYISCVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Z5</accession>
    <name>A0ABQ8V9Z5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_897079</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050460">
        <property type="entry name" value="Distal-less_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24327:SF41">
        <property type="entry name" value="BRAIN-SPECIFIC HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24327">
        <property type="entry name" value="HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="132"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="275"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="5"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="134"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="277"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="332"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4477914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="474" mass="53417" checksum="3F63A49561BFA287" modified="2025-10-08" version="1">MKDKQKKPRHRHSPAQLIALNELYERDEHPALDLRVNLAERLGMETKTVNAWFQNKRASSKKRTLPRSAASYDNPSINSSTLSSNSSLRRPDLDEFEEDLDFQSPPLPDNGPIGLPFYGGNTENAHFEEQDNMQRRSRMRPSLEQVEQLKNLFNINPLPSTEEKQALADRIGMRYQSITTWFQNQRSILKKRQEGDTDITAASFPNSEYPFDTPARRYSAFPPPTHHPSLNLPPANSHPSLPSMPVRGRRSLSPASASSRRTSRRRSGTPYDSTLNSRPRRTRPEPYQLDALKDLFLKTAHPTIEERTALAIQIGMDLGKVTNWFRNLRQTTRRRAKKSGSGEDDYDDDDDDADYPDHDRDASISRYGSPSSSTWTNDDSVMYDEKVPIMHSGSISDAGSDDEYEEAVTPSSESSRSPPPPLGRSPSSQVNLSNLTLAALESATIAEMDKAPFKSGIKVEDALLLLTFHHQVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAE6</accession>
    <name>A0ABQ8VAE6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NUDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_921812</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="9">
        <location>
            <begin position="151"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="198"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="287"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="366"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="45"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="290"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="505"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4484002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="664" mass="71726" checksum="0F9C11F3F3D175D2" modified="2025-10-08" version="1">MTAVLSPTDALRRDRGMSIDDSSISYSALTSTDWRVKYNEVADMLAETRTELDDFHHASKELEAELEAELQRTEKAHQDLRVKVARAETERDNWKSKFISLQTTHNTITTSLQRELDRLRQEHQTVKVQLRELEMGNDDLERTERAVSSTLADVEGKYTRALEEKILLEHELIDKANVEEQCQRLRDELRDANAEISHLKDQLSTRSSTASSDSSHSSGPSFPRMSAPSSEDLLSTPAPPDLQLSELDLSTETLQDSSTSEDEVTPRKQISNSKGHSVLLQRAGFMPAQTSSLSTPPGSSSIPRSRTIPSYSSPRTPTSPTKRPAVARNPSTMSTSSTTSTASKSRGVQMVTEMRARVKNLEQKIHTRVPRLRMGSMSGRPNANALAASSIGTPTQPSGTRSVLGRTSWDNPLLNRRSSESKRSTESESEKSKKGSGDTSGWVLIMEDSPSPPKERRRASSPKKTFRAAASTSSSPTFGSSRASPLFQSTVNIGPSTKRPQSRLSGGSTATTTSIPTPTSRPATPTFLPLPTATSTTMIGQKRSTGPGGATPYAYQPKRSSLGANNAAMPPPPGYVGIRSGSSTPSDNGKALPHLPGGHANVTVRSHNAKLPASNSAALLGQSRIGRPSGTRRKSAEASSDNTLRSEPVRARPGSAAAHRKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB30</accession>
    <name>A0ABQ8VB30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_771058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="44"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4481355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="496" mass="53865" checksum="DE2AE6EC3CBF0EF0" modified="2025-10-08" version="1">MASAILSILQTNAVHNLIPKREKTKKQKSLLKALVGLNARQWAEFGTGWLAWICDSIDFYSVSLSVTNLSTQFGKDTTDITRAITLTLLLRPVGAILFGMISDRYGRKYPLALNLLLISCLELCAGFVQTYSQFLALRSLFGVAMGGIWGLAASTGLENLPIETRGLASGVLQEGYAVGCLVAAIIDLYLVPEQAHSWRALFWCAAGISMFAAIVRLCLPESQVFLTARAYARIREDSRGRRTRGLHRTKIFLNETKKMLRRHWILCIYAVVFMSGFNFLSHGSQDLFPTYIQISKGFSAHDATTMTIIGFCGAIIGGAVSGAISQYIGRRLSMILFVLLGALFIPLWILPNSFAGLAVGAFCVQFGLQGSWGAMAIHLAEMSPPAFRATFPGVVYQVGNMASSASAQIEAIGGNNLKTTISVPDSMKNPTGQEVVPDYGRVQGILIGCVAAFTMIVTAVGPEHHGYEFEKHRVAFEEGGADNDAVLTEEVPEDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBA9</accession>
    <name>A0ABQ8VBA9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_769606</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4484440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="131" mass="14851" checksum="1AACEEB8378C9E18" modified="2025-10-08" version="1">MEKCHKHTHLHDSDGEVSPDSLFPASTSNRAGSSDGGLGLDVENDCDVQTKKHVCPECFKRFSRPSSLRIHTNTHTGITPFSCPYLGCGRRFNVSSNMRRHYRKHDCQSPGDNLKNLSKLHSNHPFWPTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBD9</accession>
    <name>A0ABQ8VBD9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PI31 proteasome regulator N-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_840913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome inhibitor PI31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045128">
        <property type="entry name" value="PI31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021625">
        <property type="entry name" value="PI31_Prot_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266">
        <property type="entry name" value="PROTEASOME INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266:SF1">
        <property type="entry name" value="PROTEASOME INHIBITOR PI31 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11566">
        <property type="entry name" value="PI31_Prot_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI31 proteasome regulator N-terminal" evidence="4">
        <location>
            <begin position="22"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4482634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="390" mass="41003" checksum="0EA9002D6BD5D625" modified="2025-10-08" version="1">MANILDASALTSLIPTLLPPNQKSLQSPQDALAVLSHAILSSLAFRLIAVDDSNNHNEINSNSLPENWNSHGPGGYTLRYKHEQSSLEFVVKLTKLGKRTVVNAIAVESDKTSTLDISTDDFTSPSSFPYILNTDTNSSSTSSPLVHCYISSSRITDFVSQFKLKIIQKLVPGLRKDGYTEEVDLDNKSSTSTTNNPQSLNPNRTGPSRTIPRYNPDEEEFPMRFPPPRNPSSHIAPNNPLEIGRRDLDPIPGGSFQPPPLFPQSGSGDGMFVGPDHPIFGGRIGQGQGSGGGFGPGIGGGGIGGIGGRGPRWGGDGFLPPMGAPPGARFDPVGPMFGPGPGGVGIGPFPGGGVSGIGSSGTGRRPHNLPGQGDPDNDEFMPPGAENMYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBS1</accession>
    <name>A0ABQ8VBS1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication regulator Sld3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="52999" checksum="457C82413AF393C2" modified="2025-10-08" version="1">MASSSSSTRSSASTTLLPSSLTEAQGDYSPPVIDSTNSPDYNGSGSLPAFTYPGSLVPFCFPPESALSLSVASGLDLFCSAQMAVRTLQVLTDDSPPTESSEVYNVFEEAAPFLVYIRDFWIGQTNCPLFAEHVLLTATFLSQSLPAFLRDNLEQQWGIPPDHQSQALDPSKFEQFPAIPIPFCLRFREGSAMMRLVPSKDLDVFASLRGKGSPAVASKISTPSPPLEIKPSTSVSKAPVAPPRLIRRNRELESLKADASTFFSSPRSTHSKDSDNELLSGFPSVDTASRVSSSTKVSVGRKETKSSTTVKVVEGSKASDPPTSSLVYKRVRLPPRARKIAPATSKGKAQQIVVTEEDLTPSEVESEDEDEEEDTAPPPKRLKTTSSISASLPRRSIKRVSVPKRVTKAAVKSAPAGSPDSTFQPVLLADAQGRLRLPEQSTGVFTPFPKFAHARNSASLTRENPLLAINPDFIELGSILETQNARLRCRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBS9</accession>
    <name>A0ABQ8VBS9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="165" mass="19416" checksum="508AFFB995CC712B" modified="2025-10-08" version="1">MSESLQLAVETQIGMNWNYYIQLVEITIVIYDYLLTFDTEVERYWKQRTRFTFATTLFFVNRYLNFLGLIPAILFDFWPEFILHHMGCLALNVYHWGYIFLVSSVIDILFIIRIYAIYGCSRRIALYLSVLQFQLHLASKVIEKIDYASPLIDQVGCADIISGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBX5</accession>
    <name>A0ABQ8VBX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_982022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="720"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="808" mass="86101" checksum="91920E26889AE7B1" modified="2025-10-08" version="1">MTQGFTLSYSPYTLPKAMPHPKIPDSSTVPVTQQTAPIFSLPPDILYHILWDLSGGWVTLDPTTDIWVFTRVSRSLRFVGLSFANLWARVSLEPDDIRNYKRNAVNILHAILNRSTVNVSGNGHDGTLLRLRVYADMLLIHANLLDILTAHYTRWYSLDLHISLFLLNTLSAQMAPLGFPLLSHLRLSLGSDQTKIPDLEVFSLCPALKSIEFDSIPRCKALHLPWAGLTRIVLKERVRSDFLRMLLSAPALQHAELISVLPSLHPEDPNDDPLPKSRIIEHHSLKSLVLKCIPFAVVLDSLYLPNLSQLTIESTAQASFGNLLGFIRRSNENSKLEKLTLSGSLFLTEPEGALARSLSSSSLPSSLPPSPLSESGPPGSPFNVSENNSRSASSPDPKFSVPVTATLEDVLKAAPSLKTLILEDWTPVRNPSPYDQFFIAISRCGDGDGSIGLLKSGVSFPGTPVIGGMTSAMAAMTPGFGMTPALGLNRSSSLSSSNVNGLAGTLPPASAIPLHLQRIGSQSYVNSPLPGLPPHLANNPHIAAASAHLAAAGIQLPPGALTLGMTSTTAPAMADETVNLNGAHTQSQSPGPFSPGFAAGPSTSNSDFASALAYRENSDSPSDKSEGGRTPAAKNAAHSVLGVSCCVTFHPLSLSFILCSSYFSGIPAASDEVLLPNLKTLTISNLSKNIIDLHLLAGMVESRWRGQISDRTRTSGDFNAASASASAITTPTGSPSSSPPPITSSPLTRSVSPSIVSSLSLHTDLRLIKNKGSVGRIKSLQKETEEAAREGRGEKVKVYVSAKRWGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC26</accession>
    <name>A0ABQ8VC26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small nuclear ribonucleoprotein Prp3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_837831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24163">
        <property type="entry name" value="RWDD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017359">
        <property type="entry name" value="Phi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059181">
        <property type="entry name" value="RWDD2A-B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15955">
        <property type="entry name" value="RWD DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15955:SF8">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="1">
        <location>
            <begin position="111"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="231" mass="26497" checksum="FB3C74E6FE25D630" modified="2025-10-08" version="1">MSGWKITMFGSRLLYHLYNRNLVAVKGEDISRDEQERWQRIVKEKFEDIGDSEYPIYQLFSLDLLPMLRGEADNIHADRETKLLEPASTHADVLSLRSSRSSSSKVMHHALFISHHLISPTKRRNLQQWSKSLCISGFAKVGYPGVIYAEGIQENIEEFVDNIKAMQWLALRLRFIEPVLEGVDGYSSASRRQWTEFQKVGDVMEEMRRIGRQKYVVEMGIGSAGTSKGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC51</accession>
    <name>A0ABQ8VC51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glucanase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_911362</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047009594" description="Glucanase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="484"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="455"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4476819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="521" mass="54180" checksum="0B83EE97543B1703" modified="2025-10-08" version="1">MFRSAALISFTFLAVAYGQQAGTLTTETHPPLTWQQCTASGSCTTQNSAVVLDANWRWLHDVNSATNCYTGNTWDATLCPDPTTCAANCALDGGDYSGTYGVTTSGSALTLKFVTQSAQKNVGSRLYLMAPGSTTEYQQFKLINQEFTFDVDVSQLPCGLNGAVYFSQMDADGGVSRFPTNKAGAEFGTGYCDSQCPHDIKFIDGLANIDDWTPASNNPNTGTGSTGSCCAEMDIWEANSISAAVTPHPCTVTEQTSCTGTTCSSPNSTAGVCDQAGCDFNSYRLGDTTFYGPGMTVDTTKPFTVVTQFVSSNNETTGTLSAIRRLYVQNGVVIQNSETNIPGITTTNEITADFCEEQKTAFGDTDTFDQKGGLTGMGTSLADGMTLVLSVWDDYAVNMLWLDSTYPTDGTSPGDFRGSCATSSGVPATVEAQSPNAQVIYSNIKVGPIGSTFSSTGSTGTGTGTGSGSSSTSSATSTSSAPGATQSVYGQCGGTGYSGPTTCASGSTCTESSIYYSQCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCJ0</accession>
    <name>A0ABQ8VCJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7719 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_467103</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056136">
        <property type="entry name" value="DUF7719"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846:SF1">
        <property type="entry name" value="DEACETYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846">
        <property type="entry name" value="YALI0B21296P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24841">
        <property type="entry name" value="DUF7719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7719" evidence="3">
        <location>
            <begin position="124"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4482680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="195" mass="22552" checksum="0980E5BE21F9171E" modified="2025-10-08" version="1">MPRIRQRKPNTDPPKSDAKPLIDIPEEEQWRLINESGVLHKINSNQRPSESADSEYSLMDEILDTNMIIIPFCSILLLMDILIHNQYGRHASFKELFDSMSSRGPILALFIFYIHRHKRSRSIQLFLFILSCAAGARLMYLIALGSWLVNMRQCPPLATIWIYTALELDLVPTVISLTVTASFVWWKGLQRYLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDB2</accession>
    <name>A0ABQ8VDB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_920793</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058580">
        <property type="entry name" value="DUF2828"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056690">
        <property type="entry name" value="DUF7788"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011205">
        <property type="entry name" value="UCP015417_vWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31373">
        <property type="entry name" value="OS06G0652100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31373:SF27">
        <property type="entry name" value="TROVE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11443">
        <property type="entry name" value="DUF2828"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25043">
        <property type="entry name" value="DUF7788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015417">
        <property type="entry name" value="T31B5_30_vWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2828" evidence="2">
        <location>
            <begin position="63"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7788" evidence="3">
        <location>
            <begin position="495"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4489119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="730" mass="82180" checksum="5564A5305B1B51B5" modified="2025-10-08" version="1">MASTISLTTQKITIPHIPELYDSNFLDVLLPPSKDDVVMDIGTPTPTNAMMDALQTTTHHTFTENGAPALSSTGSPTVDAFSGLNSSSNAKKLDVLLTKSWQEDPDLTLRLIWQLRSIHDGKSQKEGFYRAFGWLYKKHPRTAIANLHMLVRPVCSNKKRPELSLAHGYWKDLLNILALATTGELDAMNATFLHHPRNPCTYSRDKRKEKLTSEAHERHNAEAQARAKARRTSVGEERHEILKRRLEDPNYRALYVMVARLFVEQLIKDMRVVRELQQLPPNENRIPLLKKLSLAAKWAPSSGASHDRVTNISTAIALLLHHSRSQISQPFPSALSTFDTAQFANPELATDPYTILRSYLNRWVLIPIRSLLLLPEPLMCSNRWSEIRYNRVASVCMKNNTEHFFQHDPDRFQQYLIDVESGKKTISGATLLPHQIVTEVVKINTVPHNTHLESLNKYPKLQLFKKELAETKLRVLEAQWKSLVERVKESGSLENSLAICDVSGSMGLLASSTSRDPSPIAPAISLSLLLAQLARPPFNQGFITFSASPKFVTLDPSLGLARTIEIMQGSDWGMNTDFNAVFLKLLLPLALKNKIPKEEMIKQLFVFSDMQFDVARHGTASEKGDDWKTNHDHIADAYTKAGYDMPRIVYWDLAGYGTSEVTAEREGVALMNGFSPSMLKVFMGEEDELEDGWEKVGKTKDEVDSEKFNPVDVMKRSVMKPSFDGLVVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDD7</accession>
    <name>A0ABQ8VDD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_767095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4489150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="38714" checksum="BC5CF53412E76D72" modified="2025-10-08" version="1" fragment="single">LVIQNVERIGQNPVAGGGFADVWRGTMNGKAVCLKVLRLVIEQDEGARATRFCREALVWRQLKHPHILPLLGVNMELFLPSFCLISPWMENKDIITYLRKNPDHDLYRALIDIVAGMCYLHSRDPPIVHGDIRGANILVTNDGRCCLADFGLALVASESVTQVWSITSSGTTKGALRWMAPEYLESDGLAPTPIHSSRDVYAFGCTVVEIITRNIPFHNCKTEYTVFCSLMKGERPGRPISNEWCVDNLWELVSRCWAQDARERPSSNEISNVLYRELESKHRREREDVQRKVQHLVKRIQRKKKGSGKYVGNGSHGRDSAKIKLLGGLVHWRIHPRKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDK8</accession>
    <name>A0ABQ8VDK8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_981845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046224916" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4488680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="565" mass="62881" checksum="6FBD3ABC6BC3F9DA" modified="2025-10-08" version="1">MFIQLPPELILSILSLLDLSCIQAFSLVCKICKRLVDENESSIYHALSAYRGYIDSKTAFNQLSSLYSSKSLVGVTNWKSFCQRRVHISKSWTGKASSHYVSYAGSGSKVHRIKIDEQAGFIVTSFRDGGLLVNDLTDDQVLWSLPKTYVKQFAHLEYGEGFLIFDRLGGNKEVWHLASEFPPTPPQSNTLPDQISASEESYQKHAATYPKGHFKPWAILRMPRLTSAFRFVYPTLLVGGWDHAFLWDIPSCELVQTITSIQEAEDPNSAFAVVVANAPSFDAPAPRLGPLGNLNYVDVDEKHIFICGVTALRVFSRATGKCVLDVSSARREFGSRKFSVIYESETLTEGAALVNHFTDGEEFSLSSSSFQPRIIDEFVAVHVSSCGRHLVAMLASARVVVIENFQEGPFSLYNRMVQIQLGASRSPSKYLAIHDDRVVVANNNGLFLFSLSAALEAKVKPDASPSGTMVISRAPFFGYHVYMSNVTCLQLSDIGLYLNWDPSHLQLCLEDEAEQARLDALFRVSVNDRTSRHARMPTGDILIMLDEDDFLTEKSTVCGIDFTPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDT0</accession>
    <name>A0ABQ8VDT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_738487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="129" mass="13983" checksum="626FC8A1237AF4A0" modified="2025-10-08" version="1" fragment="single">VQDALAVIPTTAQAIDNLYGPTFADNGTLTVYLAASCSRCRDGATQAALSSYWGVNNIHNACYRISATPKPTANRAILCATILALQAAAQRPEKRLLLYTSSEYLIRSFCFWAADNAEHAWDCAHSDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEJ7</accession>
    <name>A0ABQ8VEJ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_837887</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10556" checksum="8CB970995027038B" modified="2025-10-08" version="1">MRCRLITGSLIVTLDHCSFAIFLDNFFLLLVLTSDCWASVEYSCTDCRLSPTSDTSTQRFEPRLEFRRRLYQTLLPASNSMWTERLSHSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VER6</accession>
    <name>A0ABQ8VER6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047168805" evidence="2">
        <location>
            <begin position="23"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="533" mass="58721" checksum="BFD428E5057ABF3E" modified="2025-10-08" version="1">MVYSRSVLKAVIAVGAASSALAIPLPSTSATPEGAPAASATGITQATAVGSDAVPPVTGIPPTPQTAAGSTLPPAQALGGPSSQARALNAREFNIIFEEDEKPHKHHHHGEHFGEEHHHHHHHHYHHGEEELEIEVKEHGGHRHHHHHHPHGEEEFEVELKEGGRRHHHHGSHHRHGEEEIEVEFKEGGHRHHHHHAEEEFEVEITEGDRKHRHSHHKHHGKEEEFELKVEQRPGHRHGEEEIQIEIEGLPHRHHHHGHHKHHKEENKVEIVAVPIHIPGPEHKEHKMFEPMSKTRKPKGEFEITVELEGPPGERPTVQMGRRGDDDTTAGNPAPTKEGSKEGGKEGGKEGGKEGEKEGGREGGRKKGEKEGGREGGRKKGEKEGGREGGREGGREGGRRKKGEKAKEEEQHEEHLEHDHDHEHNHNHPYEHQHEHQHQHQHQHQHPGGQGGEKKKEEDKKEGGQEASADGTPGVKSTSPPPALDATGATPGSASGSTSGSSSGSSGTPGTSTRRSLTRARRSSPFLYGFDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF51</accession>
    <name>A0ABQ8VF51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_920038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="402" mass="45886" checksum="2C4CE0B2998ADC25" modified="2025-10-08" version="1">MPSHNLNHSGGVFIPTVDQFVGKTTSGEGASSYMDEVQRLTCRFKPQMEKFIKDEISLPLWEPTFDLPNLKVPQKHRQFIHDLKIPRARAPHDHLPDMLLHNLGRFQQDEQLKARIQGLFTTHPTHKIFVNTSGAGKTRAVLEHLCSNWGLYFSCHDDSHVGSKDVPSAMSNIRKTLNQSTLPHAPNLLVTPADIAAHSRNKDVYPSDVTEEDVLRSRIANFKKDVPKSDKFSQALEKNQQLAGSSLLVPLLARLLILQQYIATVQSVDGDLSQMDHKRRWLHLQLHPHLLSSNGQDDLFHQLGRDLDNYFKKENLDLSQKIDIIQSLSHEILQSVREALGLNPRKRKPIPLYVVIDECQFTVTDMENHYCSSQWTAKGGILREMARWWDEVLNRSADGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFX8</accession>
    <name>A0ABQ8VFX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="289" mass="31618" checksum="D0F7F073D16C54FB" modified="2025-10-08" version="1">MNAEEEPGASYFPTHSCRNDDKIIYSEDGTMGYSNRSSEYNDTDQSILILESTTSASISSTTDGRISRKMDPVSTPKPTICDIDSQIPESTENLSMLLSPEALFSQVVSVNTRGKNNSVSPSERSGCPAEESSRPSEGLGHPLEGSGCPAEGSSCPSEGLGYPAEESGRPLEGRECSERFLNIVIVDDLQLSRIFFKAGALVYLLFLIRVLQKIYVMFRSQPLAVAIGNLIFSILLFILIQYHPPKQVKLEKKSMIPQIAVDAIIFIGAFTCVSFVLQMILIIAELVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFY5</accession>
    <name>A0ABQ8VFY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_831091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="498" mass="55767" checksum="61201F0D36B53FAF" modified="2025-10-08" version="1">MNYGAPPAFKHFSSASYPPIQSFNQTCSSSMVPDCIEGSYGRMPTEWIRSEEALRIQTSCLNVNDGISLLELKKHIENGIDKKTEKEYKRQNFREKRNSVQEWLKSVEVGQDPSLLGPVGYGSSYDRTGVTTTPRAFLIDRFETQKNDDRKEKRDRRERRESERKQRHKTSEATKSVDKSSHADDTWDSESIINSRGTTSLHDQPAFRSLPTAKADILSAVTSVMAHVNDSKLHLDVSNSDLQKSTGASTDGNIKSKVSCTVVHHASSFIRDSEETLHQFQEHFVNASGPDYLGLPALEVDEGADEEEERLEGEEGAGKIKGYEKMGMDLAVSSPHHSQEHGIEFLVNLQKLGTAEKKSTMTAEISSQSHVSVASPECSSILSPQVRNMDSTWERDEQALLPRSLAEEMMFAEQTQVEQYHHDDEGVFVPSHQILADEDDEDIDVVDAEEDTEEDTEDAFEVVEIDEAGSVVVKEEEKRKRRSNCDDIESVSSSVCIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFZ7</accession>
    <name>A0ABQ8VFZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase NM domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_831098</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF18">
        <property type="entry name" value="ISOVALERYL-COENZYME A DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="40"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="157"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="268"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4493176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="429" mass="46977" checksum="0E81DB5CEF06BE06" modified="2025-10-08" version="1">MLRTISSRISRRFYTTSRYETYHGGAIKTYYNPTLTGLSPSENEFREAVWEFSARVVKPKVDEIERGGSYSALMELHKEIAGMGLHGLTVPAKNLGLELGYTHHLLAMEALSYSSASLALSYGAHSNLCVNQLSRWGSEAQKSEWLPGLLDGRYLGALAMSESGAGSDVLGCMKTVAKKVDGGYLLNGNKFWITNGPKADVFIVYAKDVVEHGAKQTYTTFLVPRTTPGFTTGKPLDKFGMRGSPTCELIFTDVFLPPSSILGDSQHHGAKVLMSGLDLERLVLSGGPLGIMQAAYDTALEYVHQREQFGVRVGTIGSMQAKIADMYTKLNTARAFVYSVARAVDHHTQEAAPGYPVFQRRDCAAAILYATDKAIEVALECMQCLGGNGYINEYPAARYLADARLYAVGAGTQEVRRWLIGREVNSDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHF0</accession>
    <name>A0ABQ8VHF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_315929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF405">
        <property type="entry name" value="ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="3">
        <location>
            <begin position="448"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="766"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1031"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4494366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1308" mass="144307" checksum="AF8828798062083C" modified="2025-10-08" version="1">MVGLNPFASRHNSVHPGTPPPYKEDDPTSLLFAETTVTTTEVVTTTTQTTTHFFSLPHWRKRATPVPYSNSTVSARHPPEQPRVDEMGFPSSSRLIVDKELPPTPESSSSSGHNTPLADSRETSQRTSLEQETLSPTLFPSSDSTRLYFGSPQRPTSTSALAQASLGLSLTHVLPLASSSSSSAETNSVAFISTPSSPELPSLRKDQRGQMKQRATSTASVSLQSGAHNQRRARGLSLGPSGFLGLGTSDAKGKEIEKAAPQSATRPPNKLTRRASFWSRKKATSPDTLPVARKSDINLTPLPPLPPLSPFNVDMVKSTSQSLKPDHARTLSRSHSERNRRALLKTSEFELPSLILPGPEVPQPEKVRRPLTADASHSRLQLSRFTSAGSSEFIPSPFTSPTIETRENFSLVEAPSPSKRPRAQTNPPLLRRLSMNLFSPYSANHSHPAPSTPILTSPSPLRISTSKPTQIPKPQMDEESPEVYLSRLMVSVSKAEIGGILASSNDMFHVQALRSYIARFDFANDPLDVALRRLLMDVGLPRETQQIDRVMQAFASHYHQLHPNLFTSEDQPYVLSFSCIMLHTDAFNKSNKRKMTKADYIKNTRMPGVAPEVLDYFYDNIVFAPFIFVEDPVDVNGQHIFNVDGSRGLPSGSSFSNANGSTLLGKGNKVDPYYLISNNLLSHLKVDVEIFVPLTEPYSAQGTGGPWNEEELQRAFVNPNVIVMGPLDSSRAPPSSPFFSSGGSTSGPFATGSNLYAPGNETWRLKVTKVGSLNRKEDILEGGKKASNRKWKSFSVVLTGSQLLFLRDPAWATMFLNQNGTSTESGFFPQAAIFTPNEVISLKNAVAVYDQSYLKHDNIFRLALGDGRQFLFGTDSEFEMNEWISRINYASAFKSTGVQMRPVGMSGKDVELTGVAAATSHLHDLQHNQTKSEWGSEASRDLMDMLSGESDSPFKRALPKRRVTMMSSSSVTDNDVPVAPEVEGADQFKATFDQVKADLAAGRCASPDSESPIEEHDVERTDSLPEDDSHLPPRSRIVLSKIRELDTKISASQSQLESDLRFAKNVATLTPFQRSTRERLSMAVQNIAKRVMQVRLDLAKYTCHRKVLLNDMTAESQNWSRANKIALRAALETLQSHQRPFVPRMTLSFHETNGLASPEVSIPPKMYTPSVHQSESTAGSLQSFHSAFDFGPDWNSNDDIFSPEGPDPYELDTSLRNSSSGSLNPELFREEDDVIPLPSRPVELLSTVTSPRASHDEINHHEKYYSARESAEEQAEEWNKTRCAHRVSLVRVPSAIGLARKFERDPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHW5</accession>
    <name>A0ABQ8VHW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane amino acid transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_895643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF461">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="31"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4493358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="495" mass="54801" checksum="F44770C3BB67FB58" modified="2025-10-08" version="1">MSVHKMDEKEVEHARKTEHQRELDQARRALRTATWVSVFFLITTDILGPFNAPYAFSQVGYVPGAVLYVVMGGVACFTGLQLWRLFCRLDSHEFPVKTYGDLGERIFGKEFKHFCTVLQSLQLIINVGVICLSNAQSLEQLAANHQFCFSISVLIWAIVGMLLGQVRSLQKYGFFANSAVWLNLLIIFTSMGFVAHSPPNFAAALTSLGQPEGPVQTAKFVSLPLFDKVNGIMQMVFAYGGAMIFPEFLAEMRRPMDFWKGMICAQLLICTAYLMYGLFVYSFQGQFTLPLAYQGVSKQSWQDVGNVFALITGIIAAGLYGNIGIKVAYYSIIEDWFKGPALTSRTGRVIWTVMVFIYWSLAFVVGSAIPQVASVSGVVAAICIMQFSYTFPPLMMLGYKMKIAAAGLIAEDSLAIGDVIDANTPSKDPGDTWMQWSRWKRGFFGGTWYYNLFNLILFLASLSMACLGMYGSGTAIKATFQLEGAATSFGCRSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHY2</accession>
    <name>A0ABQ8VHY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_763080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="116"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="495"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="582"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="671"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="594"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="674"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4495239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="882" mass="99659" checksum="C762D9DE80062301" modified="2025-10-08" version="1">MEPYTPRTQTGARKKNITLSQREYSKITGTIASVRRHRLQQDDIDGELNGRVHGSSFEIGRDWEEPSFIAETSFVKAPLNSRVSLGGNAIGNSSKGKAKQESLDHIPIDIQETLILEDLLYVLMGIEGEYIRFHPDYSPDEDDPIHGVKFVVEPSLDPSVRNLVERLLPLGTYYTGISAFIEHRSHLDYGLVNHALCAAIRDMLKDYQTLLSQLEHSFNTSPQFSLQKLWFYVHPTVHTLSIIYQLTLELGTADDPSADLSSSSNSPSTSDAEEEARNEALGIGTAKLKSVLSENGLGTSSAGIPVKGGEVLSIIYERMQSMSGDPTANMVYATLLREAGTPYVNMLKEWVMTGRLADPYEELMVKESKFINRGILEMDYTDEYWERRYTLRDGSTISGSKGHKAGIPLPRSAGGHLPGGACIPPLLEGWKHKILLAGKYLNVIRECGIEIHRVQNDPDDETFSMNDERFYTFLEDAYTHANQTLLQLLLKDQDLIPRLRSLKRYFFLSQSFFLTHLLDLASNELRKSTRSASLVKLQSLLELTLNTEEREDTMFREDVKVVMAGSGLYDWLMKIISTGGLGSERVGESEVGNEEAKKEQKDDKKPLLASDTLALDYHVKFPLSLVISRKTILRYQLIFRFLLHLKNVEQSLGLMWIEQKTTPWRQRVHHTLRPSSSHSNFNSTPTSTPIPTTPAESSSSPSPFPSSLPSSSSSSEPEFEKWRLRVFLLRVRMLAFIQQILSFATFEVLEPNWRALEVKLDKVTTVDQLLRDHLDFLDTCLKECMLTSAKLLKAYNKLIVTCATFALYAAPYTKSANQAISGTETAEGQRRRWEYQLKFEKNFDHWFKVFLDCVQFYASSENGSLLPLVVRLSSISRRSTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI01</accession>
    <name>A0ABQ8VI01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_833665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046222057" evidence="1">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="156" mass="17531" checksum="F00019014BE0AB86" modified="2025-10-08" version="1">MHLSTTIFLLFGLASITWAAPRPLDILDQTSRFDGREILPRTGEVIRHISLSYLVESEYGRGVGGHNHLSALEPEKKISVENQIKKVFGSKKIKEHLGDDMMELTFQGTPLANINGVVRFRFDEKPEGFLEGSWWPNLCTFTISGSAPLTVKFKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI02</accession>
    <name>A0ABQ8VI02_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_918989</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045328">
        <property type="entry name" value="Kre9/Knh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28154">
        <property type="entry name" value="CELL WALL SYNTHESIS PROTEIN KNH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28154:SF1">
        <property type="entry name" value="CELL WALL SYNTHESIS PROTEIN KNH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047481124" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4495274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="24554" checksum="0748126C6805328C" modified="2025-10-08" version="1">MALVLAFVALDAFTAVQATLYVIQPSAGSTCSGGSPCTVQWLDDGTTPLNSNIGVTTCGLYTGDMQLVQTIDPVDVSSTQSLVFTPLSDAGPDSSDYYIAFTSTDLEINGTKYTSYSPLNNMTGSFSSSVASATSSIPFPSSLTESSAFSETGILSTVTVGTITPSSSSTASSLSETATIPSSSKFSISRSSSATSSSSVSASSGASASTSTASGATSSNGAASLRTASLTFFGVLSFTLILFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI98</accession>
    <name>A0ABQ8VI98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_827692</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10881" checksum="1E9CC5EED391498F" modified="2025-10-08" version="1">MAEVESSPATIEINDALFCQHYKEVCAICGYDGREENDAFFGFDPIDREGIEAPSATINKDGDYQCKKHALTACNQCYGWKKQITRLRTQAKKAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK00</accession>
    <name>A0ABQ8VK00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_761552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="34021" checksum="823116D7607AF321" modified="2025-10-08" version="1">MSLDALNITSTYHRDTYPAISPTKPSLSQAGRAILITGGGGGIGFEIARSFARAGASTIIIVGRRTAVLDAAAVKLREEFKDSTTEFIAHQGDIGDDASISSLWDFLNSRNIFVRVLVLNAAHFTPWGPDTLKMDKRELMEGFDVNVGGNFLMTVKFVNQPLRPAGQQLNLINVSTASIQMIPAPNQTPYSTTKSAFTALIGRIADEHPVEDIQIISYHPGALYSEGAARYVDKNLLKWDEMALPADYAVWAASPEASWLHGRFVWAHWDIDELKADKGFLKRLEEEKGFLRVAVQGLKEISLEAFLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK44</accession>
    <name>A0ABQ8VK44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mo25-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_761390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="329" mass="38502" checksum="E43E0BDAF4B87A7A" modified="2025-10-08" version="1">MNFFKTKQRTPPDLVRGIRDAIPRLESGAPASETRRRANEECSKNLQQIKALLYGDGDPLPEVVAQLAQETYNTDLLHYLVQNIARFEFESRKDVVQIFNNLLRRQIGTRWPTVEYLSGKPEVIFSTLAGYENEEIALNTGMILKEMLRHEQLAKTLLHSDKFYNFPHYIETTTFGISCDAFVNLKETLTRHKPMVADYLDKNYDRFFSSYTTLILSENYVTKRQSLKLLGEILLDRANFNVMTRYISNEANLKMMMNLLRDKSKNIQFEAFHVFKVFVANPKKPVQIENILRRNKDKLLVFLKNFHNDKEDEQFSDEKQFLIVQIQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK73</accession>
    <name>A0ABQ8VK73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Velvet factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_246164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="6">
        <location>
            <begin position="23"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="188"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="436" mass="47953" checksum="F11FA82FD1DF9534" modified="2025-10-08" version="1">MIQQTNARQRHGPSTIDGPEEWGQWSGRKYYSLQIVQHPLRARMCGFGDKDRRPLAPAAVAKMVVRRDDNGLVEVDDVDCSFFVVTVDLWSADGKQEMNLVLHPSSADRYVPPPTPNTTKSRRKGVTTSSMGPPASSSSSSNTNSTSSLPPSQSLEPPFTPTNPPTWGYPSWSQNENSSEMGYRPWNNPVNTEPSTWGPQQAFNYDYSSSQAPATYSSPPSVPSMGHAPPIAIRSSFSHPHTNFTPTVPSIPSTPAPSSSSYSSIPLPRHTYTRTLVGPLSANATRLLDEHRKPGVFFLFQDLSVRTEGTFRLRMRLMNVGKYPAPEAGATGVMSIDDRDGHERGVPGVSPVLAQVYSEPFTVYSAKRFPGVPGVYCYCRSFLLTDHNFPTDTTALSIAFGNQGQKLPLRNRHGNSSGKRRRRGDDDDEDDSEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLA0</accession>
    <name>A0ABQ8VLA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_823485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="216" mass="23653" checksum="1E423141276B2FAC" modified="2025-10-08" version="1">MRKLSYVITFLAVVVSLIVTILSLQRVDWLVVKTPEILHTQITVRYGLTTLCELKHVSIPGSDNNSKFEYSSYDCRPFPKRVQDGCEEENSGFCAAWTSAGYAVEISIGFAVLALFAILIGVSTGSRRRRIWKAVAGLVALQSVMQIVAFAIVTDTMRTGAFPTFEDAKPGTGYALSTFTWIFSAVIATGVVVTGVFADKGHKWAAGNRAYRRIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM24</accession>
    <name>A0ABQ8VM24_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">chitin deacetylase</fullName>
            <ecNumber evidence="12">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_762130</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10952">
        <property type="entry name" value="CE4_MrCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF98">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046263618" description="chitin deacetylase" evidence="15">
        <location>
            <begin position="26"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="16">
        <location>
            <begin position="138"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4496485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="365" mass="40501" checksum="D23DCB83DEF7EC5B" modified="2025-10-08" version="1">MQSLSVYRLHKLLVVVGLLHVRVNAQTSTADRTTETGEAAITDPNEECSPYSYPPVVNQLSAFPSIWEAASILSDDSAAQAKWDSISANIPSNISVKTQPPASNYSSDDPDCWWTYSLCTEPKLSGLPVDISAAPEPSTLGYGFDDGPNCSHNAFYDFLLSQNQKATFYYIGSNVADWPLEAQRALADGHEICAHTWSHPYMTTFSSEAAFAELWYSMQMIKLAVGVTPTCWRPPYGDVDDRIRSIANALGLQTIMWGYDSEDADINGQSITDQTVVTNYNNFITTASNGTFNFTGAIILTHELNNFTMSEAVQFYSQLKSSFQHIVPVGVSLNKTQPYVETNYSLPTFEQCKCPLRSRFEELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMC8</accession>
    <name>A0ABQ8VMC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_866209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4496605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="123" mass="14283" checksum="1082CB4F825AC094" modified="2025-10-08" version="1">MIDIPRERSYIERERTYLNATNLNANLSECRTHRRNAKLYRPIPDRESAWLAATLYTAGAETTSGVLSWFMLAMILYPDVQKKVQEELDVVVGRDRLPTFADQESLPYLQATVREALRWHTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMF8</accession>
    <name>A0ABQ8VMF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonucleotide reductase small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_821584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409:SF18">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="418" mass="47732" checksum="2B2DF687964868A4" modified="2025-10-08" version="1">MSTTPTRYPSPGPTPSKKAAAALASFTFDSPTKKSAKKAVVDDKRRSTSPASLEENEDQCVEEETTQTTSAEELAALQKRFVGEVELPESEEPLLLESRRRFVLFPIQYHEIWQMYKKAEASFWTAEEMDLSKDLHDWNNRLNDSERFFISRVLAFFAASDGIVNENLLERFSNEVQVAEARCFYGFQIMMENIHSETYSLLIDTYIKDPVERDFLFDAIETIPCIKRKAEWALRWISDEHSVFGERLVAFAAVEGIFFSGSFASIFWMKKRGLMPGLAFSNELISRDEGMHTDFACLLFSHLRRRPHPDTVERIIKEAVAIEQEFLTDALPVSLIGMNATLMCQYIEFVADRLLVALGNKKLYNSSNPFDFMDMISLQGKTNFFEKRVSDYSKAGVNHSGDNTTTQASKTFVLDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMI6</accession>
    <name>A0ABQ8VMI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_212217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="91" mass="9964" checksum="8916324C6BEAA1AD" modified="2025-10-08" version="1">MVPSLPTTPEASEPRNQITPGKEETPRKQLAPPMKNTKRAASECPPSPSQRNKRFKISTNDFNLNGSYGVKSSLKPLKMALTKIRGSKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMR8</accession>
    <name>A0ABQ8VMR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="250" mass="27407" checksum="38A56ACD302FD4F7" modified="2025-10-08" version="1">MPTTTKTSLSPLSTSLTHIGMQYLRETLLYEILEIIGGADVQRPTRLLYTPSPGPPTINHESGDGSCVVCAHRNPSKLAPNSNSSPPSLSEVPVTSLYQTILPFLTSATLPSSVASRSATFLTVNGFSPSSPQPHFPPLSLRGVQPSSRSTSTDQSKHPADGLRRLLAQEECSKCQPLHQAPTRHSRFGLPSPCFWRARPVFVEEITERRVGALVPLWFARALGWKVASKRRNEVDRESEGSDVDKRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VND8</accession>
    <name>A0ABQ8VND8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_894325</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF488">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="549"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="461"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="223"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="282"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4497898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="657" mass="71479" checksum="CA140A5E3C3182B8" modified="2025-10-08" version="1">MASPHSLNFSFASPPGNKRNSLSQLPLPSGMSTSSSANSQPVTPNPSIIPASAVKLRSPGSPLSSTFPVSTFASPQTYSMHTGSTHAGGVQPSASFFHPSRPHYSPPDSPSSSHIHTYKDKDVFQLSELKRLSDSTADHSDFVGGDTSDLSMQEQQIINGVKQSREPLLPFGEGPPVAIRTSMAKDRSDTNHTVKPQFPHSRIGLRTSLDLVFNLRRGLSIDSHKSASTPSPAAQSHHRQVHSVSSEGGFGSIGDKRKLHDEERGYPTTHFASLRRQHSIASSHDPSSFATTSKFPQSASIPTGYKPTGSKNGQSSDEKTQFLFAVPMYTPRGKIIRKWQLHPSRNNFFSKGRMLTGGDSPWAFIASFGVLCAIAGIWFGTTCRWWWLQEGAGGKVLVCVAGYLTLIVISSMLKTAFTDPGILPRNLDPDPPYPSTSLSDGGVRAPMPRDLKVRADIVRVKYCPTCKTYRPPRSSHCKMCDNCVDGCDHHCQWVNNCIGRRNYTTFFVLLLTATLTLFLVIATSVAHLYFLTKRGIPGTPGPISFKQAIASTLGAGSAAVFCLSAVVIWPVAALLSYHIRLLLLNISTIEQIRNQAHKTLVPGPAPPNPFSHGSWRRNILAVLCRPPGYSWLDPSAIATEDRREINPGYTAAVTSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNX9</accession>
    <name>A0ABQ8VNX9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_236503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="102" mass="11971" checksum="7E6469F43E6B078A" modified="2025-10-08" version="1">MHSIMNKYMVTEESQKRRIVYSSFCSARHLLRLAGTRLRHLKFCQEYRGRSRGITRFYRWHIDAALYDLSPPRVTTLYAVRVPEGPNQICRYDDGTGDGLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPU6</accession>
    <name>A0ABQ8VPU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mediator of RNA polymerase II transcription subunit 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_757335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021627">
        <property type="entry name" value="Mediator_Med27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13130">
        <property type="entry name" value="34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13130:SF4">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11571">
        <property type="entry name" value="Med27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32685" checksum="5D7DC1A7EB96189F" modified="2025-10-08" version="1">MSPPAVESQVQALTDLYNSIQNARHHPRDLLKTAIAPNPLPLTHPSLLLYSQQLKDIVHTLRSDAVQSALRAAKESEKADGQNIMNNVRRENRKRRPPSPESPQPYTVIERQSSSLFPVTKDDVAPLKSPELIEYIRQFNKTNSSYKLGIWQGTRSSTRDLKNPTILRFTIKDVLTAYLTVSYTSNDLVLLVESVTTFGPRERKLPHSQSDYSVYRMLSQEFGRMIHSDPQVGLQKFMTLLCSYENMFTMRCDKCQRVLCVEGHVAAVERVWNESDGQWQPRHVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPX6</accession>
    <name>A0ABQ8VPX6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_894158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="5"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="255"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="338" mass="35787" checksum="99ED6E66CB9C2087" modified="2025-10-08" version="1">MPLEATMMVIDNSEYMRNGDYQPNRFDAQADAVNVVFQTKIDSNPENTVGIMSMAGKGPEVLVTHSKDLGQILKAIHTTSSKVGGAIDIPTAIAVAQLALKHRENKNLRQRIIVFIGSPLEGPAADEKGMVKLAKKLKKNNVAVDVVCFGDGIEEPVSGQEDKSVLKSFVENATSSDNSHLVVVPPGPRLISDALISSPILSDDRSASIPTELGGTGGDGPSASSGGDFEFGVDPSLDPELAMALRISMQEAQAREVAASTEASSSGASQPATTSLTVPAESTEDEEEALLAQAIKMSEEDVDMETTDAPMNEDDEDEEAAIARAIAMSMQQDEQDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ57</accession>
    <name>A0ABQ8VQ57_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_978909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="206"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="279"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="445" mass="49123" checksum="FA596A4E1F0D9C34" modified="2025-10-08" version="1">MEDDDDNNGGDESEEFSDILPPPTQALRKRKQLAESNTTQRSTHDADVLRRKLEAMEAREAKLKKKMQSYQDKAASLQRDRDEDPESEDETGERQDIQFSSTAVPLPTLSTPTPQIQRVYANHRRTKSRSLLLTPSHASPTSRPTTNTAVAGQGSISNPTDLGTTSTNDSSQTLKLPTLHMALNFQAGSRAKLDDYDGEGKAVILRAIRDFEARVMGKNFFPSDTTRARWAEDSFQAACAHLQVDYLSDKRVLTLIQGRGSCVRGDLIDKAEVPAHNYSAFLYKDSDKLIGYAENPMLLTFFTYVFVKKMALSFEAYFTPFTLEALAGWFMTIRFAIDEWSSGQQRITLNFSEQDNKLICDQYLAKAVPAKKAAGVSHIEGEVEKAMRIEMMARTGDTDSEQEESDEEDDIGSADIRAAATKKPGSGSANGGESDAASSTAGIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQC9</accession>
    <name>A0ABQ8VQC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCD97-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_821174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040233">
        <property type="entry name" value="CCD97-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018613">
        <property type="entry name" value="Ccdc97-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09747">
        <property type="entry name" value="CCD97-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCD97-like C-terminal" evidence="2">
        <location>
            <begin position="135"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="235" mass="27542" checksum="DB2DDA481D965381" modified="2025-10-08" version="1">MTSNQSFDMIPVLAYLGVEKDGSYSPSPSDQTIDFLIKHIHNLPPHLLLKFSSITSPKQRTVIHVIRNRRLKYIDTQPAELSFTSARHTWPSVWPGRERRGVAEGHDEEQWAQTDFMQGSTKHVKKLGPLLRDYEEEREAERVRNIRRTQLAAEESQFIPEEDEGSAEDEPVESGTVEEATEADNRAEFERRIRERFIYGLLDNIDYDRVDWDESLDTDNDRDMEERWFDDEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR88</accession>
    <name>A0ABQ8VR88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_105289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="261" mass="29216" checksum="19F3037BE3D28690" modified="2025-10-08" version="1">MSNPEKVVLILVGLVGSGKSAFATALESHFPRQWRRCNQDDLGNRAQVEILAKNSLRKGLSVCIDRTNIDERSVSQRAHWIRLAHEFPGTRVWVIFFDTPYEVCALRLQRRTSHPTIHSPEMGLSVLSRFARDLTVPSVNEGFHCVVSLKPVDTKVEYSDSDIVTILDRVRSSEAVMQSRPRPMRTSWAERRRQSRGGPTRDIKTQSSYLSRAWQQGTVFPTQNTSSSIQPATEVDGDIGVQAGHTHGEVSPLLTDLLGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR91</accession>
    <name>A0ABQ8VR91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_978660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="172" mass="19467" checksum="4E330B4B1FB62F29" modified="2025-10-08" version="1">MSANDYYNNQGKQYYPPQGPPPGQGGYYPQQPQQAYYGGGPPQGYPQQGGYQPQPPPQTVYVYVHELVAISISPAELSLFTDNNHSRAQAVVVDVVRVWQECVYAAALKNFASVYCNLQLARCRAWIGPLCFVDYLRVYQSFHYFMALYFSHRFMFPPYLNSSCGVQHPVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRC1</accession>
    <name>A0ABQ8VRC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_816928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="4"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="40768" checksum="E49CA2F666CD8DE1" modified="2025-10-08" version="1">MSGDLYDILHISREATPEDIRKAYKKQALQTHPDRLPPNFTPAEKAAAEDKFRKVNNAYEILKDPLKRQSYDRHGVWPPPPAETPPPASRYDPYSTRYQNRRNDYPRPNPPDPFTLFTDFHFTDPFELFDSFFRESLGAYPRDRRHSRDSRSPHRRHTNYEGDFNNFDGFGNGLSGARGMHFGGDDLMADLQDMHRNMLSASGFSRGMGMGMGFPPMISHFPTFPSLVMDTSSSSGSGRWAAESTMSQTINGVTQTVQKRRDWDGNVHITRTYPDGRKIVTINGVEQHDQGQRYIQSPPPPPTNGNANNYSSSPPPPYAIATNDVVNYGNAVAPRPSSGRHVIPVVPTFRESNRGESIVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRJ7</accession>
    <name>A0ABQ8VRJ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide SHNi-TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_877339</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019544">
        <property type="entry name" value="Tetratricopeptide_SHNi-TPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10516">
        <property type="entry name" value="SHNi-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide SHNi-TPR" evidence="5">
        <location>
            <begin position="188"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="375"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="414" mass="44156" checksum="EEF1C700A886E360" modified="2025-10-08" version="1">MSSSNTGSAKRDSPVPDISPDNAIEHAKRAFALKKYEQAVDYYATALEHFSRTLGEDSPEIADLYFAYGKSLLENAISQNSVLGKDQPEEEGAEDDKGSSSNGPILSFSGDAEEGVEDGAVDLFAEAAKEVAEADAAEAGEEDDNDEEDAEPEDDFNAAWEVLDLARAIYDKQHDADASNEDVALKLADCYIALGDVSLETEKFDQGITDYEVGLTLKSKLLPLSSRQIAEAHYKLSIVLDLTPGRLSDSIKHADQALRSIESRLEELKLAKENPSSLTKAVKPDPKGKGKGKVSAVAGINSDAVQNMSATQIEGELKELAELKEELALRIEELKMAPNETLAGSAPALAAQALDKELASKSSPLVPAAVVNDLTNMVRKKKAPTTDGSSAKRKANDGEDSGSEKKLKLDAGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS37</accession>
    <name>A0ABQ8VS37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_90129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="345" mass="37871" checksum="E7A05860FD6BB14C" modified="2025-10-08" version="1">MASQQQSGPLSDADIYALQEWIAETAVGFCLYGIYATFSFIAIYFLLTRHGGDATKKARLVLLTVIIFMFINSTSLVILDLEYILVQIPLGSFNPPDIQKTTKILGNIKISGNFLERLNFLINDGIVVWRAWILFPRNWHIKLLLGFCLLACGVCNVFDAASGAVNVLKNYQAVGAGTKEFLVLTLPLLVTNIVATCLIGYKALKHRQDIIHNLSKSSSGASRITMVQKILSLLVESGSIYISFWIAATFLTGFADSSKLSFQVFIASALPFLSGLYPVLIILLVALENTKDRSNEVDLSLSQSIHFATRVHLSAAAETVSTPEAESPGDIVENTRIYNQPKESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS59</accession>
    <name>A0ABQ8VS59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_90209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045081436" evidence="2">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="3">
        <location>
            <begin position="40"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="133" mass="13869" checksum="1692558324E425F8" modified="2025-10-08" version="1">MFIKPLLFTALTFTALSEAIPLLPRTTYTGDVTYYTPGLGACGIVNTSAQLVAAIGHIAFDSYPGATANPNANPICGKKVTASYGGHSVTVEIVDRCVGCAGEYDLDLSSTAFSELAPLSVGRLTGVTWEYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSF4</accession>
    <name>A0ABQ8VSF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein heavy chain, cytoplasmic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dynein heavy chain, cytosolic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_754915</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="740"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="1043"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="1419"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="1761"/>
            <end position="1927"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="2037"/>
            <end position="2085"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="2242"/>
            <end position="2318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4499308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="3458" mass="392891" checksum="E2D7074D473445FF" modified="2025-10-08" version="1">MQIQLLAPANSSTAAAVTFITFVQDLKKKTKTWGPMIELCANGEKTLERFRYQFPDDWLYSDQLRGEWSAYNEILKRKNDSIQEQLAGLQLKIVAEDKIVENKINDIITEWEQTRPVQGNIRADTAMNTINVLEGKLTRVQEDYDLVCRAKEALDLELTRHTRLEPVFEELRDLKAVWTALSGIWSQISDLREMSWATVQPRKLRQHIDGLLNSTKEMPTRMRQYAAFEYVQDVLRGLLKSNPIVSDLKSEALKDRHWKQLFKVLKLPAQISLTLMTLGHVYDLDLKRNETLIKEVIFQAQGEMALEEYIKQVREVWTNYTLDLVNYQNKCRLIRGWDDLLNKCSENLNSLTAMKLSPHYKVFEEEAGSWEEKLNRIHVLFDVWLDVQRQWVYLEGIFSGSADIKHLLPVESARFQNINAEFLTVMKKVYKSPFVIDVMNIQGIQKSLERLADLLNKIKKALGEYLERERSSFPRFYFVGDDDLLEIIGNSKDILRIMKHLKKMFAGISTIMLDDDLTQIQGMASREGEEVMFTEPILLKDFPKINDWLAKIESSMQVSLATLLSEAVGELQTFYGTGSNLKMEEFVAWMEKYPAQLVTLAVQVAWTASVEVALEATSAPQQALDTVNQALDLLADIVLQELSPVTRRKCEHLITDLVHQRDVTRSLLQQQVMDKNGFTWLYQMRFYLDKSISNPLDRLTIEAADAIFPYGWEYLGVLDKLVQTPLTDRVYLTLTQALDNQLGGAPFGPAGTGKTESVKALGVQLGRFVLVFCCDENFDFKAMGRIFVGLCQVGAWGCFDEFNRLEERILSAVSQQVQTIQQGLAALVKNPNTEIELVGKNLKINKNIGIFITTNPTYAGRSQLPPNLTKLFRPMAMTRPDRELIAQVMLFSQGFRTAETLASKIVPFFNLCDEQLSPQPHYDFGLRALKAVLASAGILKRERLSSAREKADADDAAIGLSDAISEQIILIQSVTETIVPKLVADDVPLLTNLLADVFPGVDYMPVDLDRLRDEIYKVCKERRLVTGERWIAKILQLYQIQKIQHGLMMVGPSGTGKTNAWRVLLAALERFDGIEGVDYVIDPKAMHKDALYGTLDSTTREWNDGLFTHILRRIVDDARGESGKRHWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLNLPPNVRIMFEVEHLKYATLATVSRCGMIWFSDDIVETSMVYENYLSTLSTTPIDSDEEDAGDALARRNNEVLPSDAAASAALETQKQVASILERYFSEGDLVSSALAFADSIEHIMDFTTTRALNTLFSLINKTVRNIIEYNFQHPDFPLPPERVEQYVTKRLLVSIVWAFSGDAKLDLRAEMGDFLRNHTGIDLPPLLPGSSLIDYDVQVSTSEWVAWQGRVPTIEIEAHAVTAADVVVPTMDTVRHEEVLYSWLSEHKPLMLCGPPGSGKTMTLFSALRKLPDMEVVGLNFSSATTPELILKTFEQYCEYRKTPNGVILAPIQIGRWLVVFCDEINLPAADKYGTQRVISFIRQLVESGGYWRTSDMAWVKLERIQFVGACNPPTDPGRVPLSHRFLRHAPLVMVDYPGEVSLKQIYGTYNRAALKVVPNLRTYAEPLTDAMVSFYLASQRRFTTDAQAHYVYSPRELTRWVRGIYEAIRPLEILSVEGLVRVWAHEALRLFQDRLVTEEERAWTDENIDVVALEYFPTISKDEALRRPILFSNWTSKDYIPVDRETLRDYTKARLKVFYEEELDVPLVLFNDVLDHVLRIDRVFRQVQGHLLLIGVSGSGKTTLSRFVAWMNGLSIFQIKVSNKYTGDDFDEDLRTVLRRAGCKGEKICFIMDESNVLDSGFLERMNTLLANAEVPGLFEGDENAALMTACKEGSQRDGLMLDSPEELYRWFTQQVARNLHVVFTMNPPANGLASRAATSPALFNRCVLDWFGDWSDQAFYQVGMEFTQSLDLDLSSYNPPALFPIVYRDLSMPPVHRAAVVNALVYVHSSLHQINQRLSRRQGRYNYVTPRHYLDFINHYVRLHAEKRDELEEQQRHLHVGLDKLRDTVTQVEELRKSLAIKRSQLEAKDAEANEKLKRMVADQQEAEQKKSASIDIQAALVEQDKHIEQRRAIATADLADAEPAVLEAQSAVGNIKRQHLQEVRAMANPPEAVKLAMESVCTILGHKIDSWRTVQGIIRRDDFIQRIVNFDTTTQMTKPLRDLMKRDFLSRPSYNFETVNRASKACGPLVKWALAQVKFSEILDRVEPLRNEVLSLEQQAETTKKQASAIINMIAELEGKIGRYKEEYALLISETQAIKSEMERVQSKVDRSMKLLESLSSERGRWEAGSRTFDDEMSTIVGDVLLSAAFLAYGGFFDQHYREVMWQEWSSHLSEANIKFKPELSLTEYLSTADDRLNWQSKSLPSDNLTTENAIMLKRFNRYPLIIDPTGQATTFLMNEYKDRKITITSFLDEAFLKVLESALRFGNPLLIQDVERLDPILNAVLNKEIRRTGGRVLIRLGSQDIDFSPSFTMFLSTRDPSVEFSPDICSRVTFVNFTMTRSSLQSQSLDQVLKVERPDTERKRTDLMKIQGEFRLRLRTLEKLLLQALNESSGNILDDDKVIDTLETLKREAAEITHKVEETDVVMKEVEQVTAEYLPLAQACSAVFFVLEQMNVVNHFYQFSLQFFLDIFDYVLHHNPNLRNVSDYNQRRDILLNDLFLVVYKRTSRALLYRDRVMLAVLLAQVKLRGVEEISDELEFLLESGDNVLASASSNEDITFLTMEQAQRLESFAKNHIFKPVVQHLREHEDEWRTFLESNTPELSVPTPWEASTPAVEALRAMLIIKCLRPDRLLQSTAQFVHNVFNTDVSAQSVYELGAMVSDEVPAATPLALVSVTGYDASYRVENLIKNTGARSSSVAMGSQEGFSLADQAIASAARQGTWVLLKNVHLAPEWLGQLEKKLQTLNPHRNFRLFLTMEANPSIPVNILRQSRLLMNEPPPGIKANLLDSLRNIAPSRLSQGPAEKVRLYFLLAWFQAVAQERLRYVPLGWSKVYDFNDSDMSSALDTIDTWLGAVSKGRANIDPATIPWDALRTLIKQSVYGGRVDSEFDQRILDAFVDALFTPNAYHVDFDLVPSLTGQKMLGVPDGTKIDQFLSWVQQLPDREPPSWLSLPPTAERVIAIAQGEELLGKLRKMRMQADDDEETITAATSKSQTSQQPAWMRQLLDRCKEWLALLPEKFNTLPAQSGESQDPLYRLFSREGAIGRRLLSQVQRDLGDVVKVCQGELKQTNHLRSLMSSLTKGRTIPNHWRIYKVPKAMAVSGWVANFAKRLAQLDNIAGVDNLNNVEVWLGGLFFPEAYITATRQAVAHRKKWSLETLNLTLDIERVNDPGAFILDGLALEGASWATDRLVLNNGEVVRLNPSQIRWVQSDDIVRGNLVNLPVYLNNDRSDVMFTVDLPFDSSAGSLVATRAACLTAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSW1</accession>
    <name>A0ABQ8VSW1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ceramide glucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Glucosylceramide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">UDP-glucose ceramide glucosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">UDP-glucose:N-acylsphingosine D-glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_814105</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.80" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02520">
        <property type="entry name" value="Glucosylceramide_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4499460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="455" mass="51088" checksum="A8CE5F46E56FB742" modified="2025-10-08" version="1">MVSISFNSEDYHDLNTFFASLGLIWFVALWCIWLLGTWAALRPRSPLSSATRTAVPGVSILRPLKGLDTNLYENLESTFIQEYPNFEILLCVAEEDDQALPLVRELIAKYPNVNAKVLIGQENVGVNPKVNNLMGGYRSAANDILWVLDSNVTVHSGTLARAVDALQAPTKSGKRVALVHHVPFAFSTESRVGSRIDKAFLNTNHAKMYLAINTVAIESCVVGKSNLYRRSDLERVNGSLKPITSTEPNAKQDGLCGLPAFGRFLAEDNMIASALWHELGLSHDLSCDVARNVVGNMSLRDYVQRRIRWIRVRKNMVFAATLVEPFTESIVLVAIGSSSLKYFFGLPRWLCILVHFFMLLIVDLDVYNSLAGHPLPQSIKWEFLAGWVAREMLALPIFISAIFGNTVEWRGHQYRVLSNGEVQHVSNHRSFFDSSKFLGWYRRQYQALETQPVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT41</accession>
    <name>A0ABQ8VT41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PhyH-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_126594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF48">
        <property type="entry name" value="ECTOINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31287" checksum="6FD16087DCA0F66F" modified="2025-10-08" version="1">MVHITPDQKAAFARDGFLILPALSKDISHNIKKWANEVKNLPYRPDSWMHYDEVIKNSKSSNTEERVLSRTENFADYHEGFKELFRGAEMTSILEQLTGEPMVLFKEKINYKQPQAGGYEAHIDSLGYSHIGNVSHLSILMAAEPATLENGCLEVVAGSHKMSIPIGKNKCIQQEWCDEQKWTPVPLESGQFLVFGSYLAHCSAPNKSDNGRAAIYATYNAISDGGDKREAYYEDRRKLWPPTAERLPEERYDTGAKIYGFGTPMLSIVEDGYKNSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTP2</accession>
    <name>A0ABQ8VTP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="8">PARP</shortName>
            <ecNumber evidence="8">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_815363</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H(+).</text>
            <dbReference type="EC" id="2.4.2.30"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01437">
        <property type="entry name" value="parp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07997">
        <property type="entry name" value="WGR_PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.142.10">
        <property type="entry name" value="Poly(ADP-ribose) polymerase, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.140.10">
        <property type="entry name" value="WGR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004102">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036616">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF60">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02877">
        <property type="entry name" value="PARP_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47587">
        <property type="entry name" value="Domain of poly(ADP-ribose) polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51060">
        <property type="entry name" value="PARP_ALPHA_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WGR" evidence="12">
        <location>
            <begin position="111"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="PARP alpha-helical" evidence="11">
        <location>
            <begin position="244"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="10">
        <location>
            <begin position="383"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4499346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="617" mass="68207" checksum="2B00BA1C50DD658D" modified="2025-10-08" version="1">MPPRKKTADGAAPAAPTRSSSRNKTAKNAADAAATATTVSKPKSKTKRAHPSSDDEDDAPAKKPASKKAKKSKTTVDEDEDAKVEDKPANIKQVIKRGAAPVDEVSGKVSTHQVYANEEGVWDAMLNQTDINANKNKFYVLQLLHPISSNATCELFTHWGRVGERGQTQTKGPFTSAQAINEFKKQFKAKSGVDWESRVGMEPKKGKYFFLERDYDEEEDTEQKNKPKSKGKGKAQTEQQPIPECTLKPEVQEFCRLIFNTSIIDATLSSMNYDANKLPLGKLSKATILKGFAALKALSEVIDNPNSEEAKRWGGQQAGCAELTNRYYSIIPHDFGRNKPPAINTQNALKKELELVDALGDMEIATELMQASNASDGEGNPVNPLDAQFNSLSLNKMDPVERDSDEFKMLARYMSDTHGKTHGHIKAKLKNVYRVERSVETEAWKNAGNDTLQNQERMLLWHGSRTTNFAGILSQGLRIAPPEAPVNGYMFGKGVYFADVISKSAGYCYPHLSGGTGVLLLCEVAAQPFYERYDAEYDADRSCKKQGKRATKGIGRTAPTTWKDAGKALNNEELEGCIMPDGPCADDPSPKGYLQYNEYIVYDISQIRVKYLFMVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUN3</accession>
    <name>A0ABQ8VUN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exo-beta-1,3-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_753875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF42">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045403711" evidence="5">
        <location>
            <begin position="26"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="83"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="46997" checksum="27FFAFF8D55236A9" modified="2025-10-08" version="1">MISSLCILTSVIAILCATSLRLVVADNPINPGFPYGSEKVRGVNLGGWLVLEPWITPSIFDNTGNPNIVDEYTFGQMQDHGTALAVLQNHWNTWITESDFEAIAAAGLNHVRLPIGFWAFDVSGGEPYIQGQLPYLQNAITWAGNHGLKLIIDLHGAPGSQNGFDNSGERLSFPTWQENESNVQRTDAIIMTIANMVKDNTNVVPIIAPLNEPAGYDGSQMLDVVAQYWYDSYGNIRFPFGTSQESNTVVLLHDAFQPLSFWSGFQTPPQWQGVAMDTHIYQMFSQELVSQTDAQHIQTACNYQNSLAFDLWLIVGEWTPAQTDCAKYLNGRGIGARYDGSFSGSTFVGSCTGLTGSASTFSSAFKTFLRQYWEAQVIAYERGGSGWIQWTWKAENADEWTYQAGLANGWIPQDPTDFMFPDICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUX0</accession>
    <name>A0ABQ8VUX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="106"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="414" mass="46588" checksum="F7D3BD4FFE8046B5" modified="2025-10-08" version="1">MSVPMSSALDLVPLVLDEVLVHTDLEPQVYDEWSTTTTNDMPCTSLIDSVCALLASDGSKSQTIIARARKPFDINNAVLELLLSDRVVFVRKLSHEASSDLTSRWFRGRCVSEVSVLRWFELVAPDLPVPRVLAVNETKELIVTTLLPGLDAVHAYPRMDALAKERSVLSYARFAVRMFQIPAPQRFGTPYDLNGPALLLGSHIGFSPEHCFDVSESTDLQSFFDGLIDSRLLSSSINHKSDPSSHSLLSLRLTRLREGIQPLIAEVIKNPILSRFVLTHQDTRSNNLILEPVSGEISGAVDWEYCGCLPAAMSAQYPEWIRPPIDESLQYRNPKDTFLHYTFELKAERERLCDLYEECVKGLDQEFWNCLVLGTRLRDAYTWIALSNGDLDGETMDRWVTDHLFGSTANHRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV92</accession>
    <name>A0ABQ8VV92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase</fullName>
            <ecNumber evidence="9">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_479007</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00525">
        <property type="entry name" value="AE_Prim_S_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="416" mass="48627" checksum="878B86FB5FBA1BE2" modified="2025-10-08" version="1">MAPSSDIDIDPTSEEVLLTFYRRLYPFKQLFKWLNRGPERAEKESRLFPYREFAFTLRNDAYLRYNSYSSDVEMKKHVCLLTPSRFEIGPVYSAQPKDKKTVRPTHFRAEKREVVFDIDMTDYDPIRTCCSEADICKRCWGFIAIAVEVLDTAIRDQFGYTKLLWVYSGRRGIHLWISDKEAFELNDDQRKAMVEYLTVIKNGKEPGKRVNVRFGMKDLPPTLKEACQAINQTFDDLILQDQDCFGSQEGYETLLSLIPDAKLASRLREKWSQKPDSPSYIKWDEMRTEILALKDKHARQNMRYAMEDILLQYAYPRLDAEVSKHRNHLLKAPFCIHPKTGRICVPIDPNRIREFDPATVPTVGQLLAELDTAGSDTSDGEHRDDWQRTSLKPYIDMFEEYANNVQEKQTKIDLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVE3</accession>
    <name>A0ABQ8VVE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_739283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25240" checksum="DF6728DB0CAFAC36" modified="2025-10-08" version="1" fragment="single">IIAVLAGRPDGDYSQELPEAFRFMLEEGEQAGLSTKAADGPHKRGAFPAYNRGITMGMGNAHPVVLNPRSMTQVLNRLVGHSAFQRMARYQNAAFGLWAPCVYAEYEKVHNTVHSNLELPENFPGVVFTASAFNFGGDVWTFKHCDSLNWAFGWCAITALGKFNAARSAQLILWELKLVIDFPHAATVLLPSAIITHSNTPVAYGDLRTSFTQYTAGAIFRWVENGCRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVU2</accession>
    <name>A0ABQ8VVU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_426187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="39629" checksum="4C6E984FE11DB27C" modified="2025-10-08" version="1">MWKSLLKTGVSDDAVANLGVDFNAMEEMVSLDDDSSSSIFSPGNRSSSSLWTSSDDSELNDAYESWSEGDTDVPEGVEFEEDRITPWSGPMGDPNEADSSSELSSDSETSEQENEPQPVGARDESLDEEIEFDPQVAGYGRWYDDEDEDDEDAYMYYAYGPTALFKTRPELQASISVFLIRSSDEPPLLPAKLFHFTQELPIALYDSPPAIHPFKSLIVWPIGRGDVLFADFSCQSYFMRKLRLTTSNSAHISVKCHFSNCGQYLFIAAFEGQRKPAEKVDDAIGIKVALLVLTYRLSESKTTRSPPRLIHRTRLDLGQKSSIAVSSFPFTLTWTSTNVYLTCSDNTLKFPRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVX3</accession>
    <name>A0ABQ8VVX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="27484" checksum="CD4948C7E9350ACD" modified="2025-10-08" version="1">MINSIVKFKLRLKKAMRGIVKSLSGQSTVPDVNVVEEAVAAGSNAQLALRVGIHLGVPGTDESESIFQNGPVDSGFVGEFIGGVLLGLEGLAVARLGKSVGGDMVEDNGDRLGDKIGDVGFDFGNAVFTAFEKLSNDKCGSILEVGLPVPPPLAFPCIGEMLLVGGGGEAGVAPDVVLTFEGTSTLFLPPPPGPTQLKLIPLIPRESFSRTFGDTDPDPSQLLSSRTGDGPWNPYPEFLPPVLPLGPNPIPIVPIIPDRITLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW10</accession>
    <name>A0ABQ8VW10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_810021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="630" mass="71220" checksum="7B47684265AEE881" modified="2025-10-08" version="1">MPECGVYASFHWEIQSKQNEHGESGLPASNPFEHGYFVVHPECCALPTGQRQNVRLHQVQDGDPDFLPLPTAQKQSECDKKGVCTACQPPTQTALDTGLVEKSSDLRKSYKSQGLTSRLTAAQIVNKLNIRGQLFSALRGKEITIGIGDYLIRISFATEAHCFWILTEKYRTIISCPTVSRGATGKAFPVPDELLVNCPQRSQVNPLLATIPAAFVRPKWTLLFLDHQCFITFHIMRLQHPCSESDFIPSSPLWHRFWSRNHGPVYSSQPQETENVLEQFRREMSNSHSMSPIWSVMKERQDIFNGFGAQESCDTLFLALIHPLMPAQFVCSSKETWTRFRSTVIEQHMFRIQRILHPDMLGVSPLAYLSKESDPFKMNKHAHEAYAATIPCYRKKTVLLSSSQLDLAHKLGLFNKDGVLGEDGIAQVPATSFPPASSEIKDVPSTPRSGYQSCKLPNYIHRFNIGSRFQHVYSPFFCRLPESWFGYNELWGGVIDFKHCVNETTLGPYSFKVFVDCAWSKEHIEVAGGETVLIGRRPILKDGTGNSKRPKKGQIPSGKEKSRVVQKNRMWHLNYGTVENQEWNDEDIVGESELLEAEMEGEDHSGAIGTSGPIRPLRSQRLLRKDHNPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW36</accession>
    <name>A0ABQ8VW36_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_817555</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="3 9"/>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="6 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="10">
        <location>
            <begin position="28"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="212"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="515" mass="58289" checksum="656D55ECC381C20E" modified="2025-10-08" version="1">MARPRSLSGTIPSMETSHEELKENTIIIVLGASGDLAKKKTLPALFGLFRQSFLPRDVKIVGYARTKMDHAEFLKRGTSYLKNPNDDPELSKSIDDFKSVLSYVAGDYEDGSAFDNLNQHLEEIESHYQSKECNRIFYLALPPSVFIPVAKNLKEHCYVTKGGINRIIVEKPFGKDTESARELLGSLKKYWTEDETFRIDHYLGKEMVKNLLVLRFANVAMNAAWDKNSISNVQITFKEPFGTEGRGGYFDEFGIIRDILQNHLLQVLSVLAMERPVSFAAEDIRDEKVKLLRAIPPIERDDVLLGQYVSANGKPGYLDDDTVPRNSVCPTFAAATLWIHNPRWEGVPFILKAGKALNEAKVEVRIQFKDVTQGIFKDIARNELVIRIQPSEAVYLKLNAKTPGLYTRAMPTEMDLTYKRRFVDAQIPEAYEALILDALKGDHSNFVRHDELDVAWKIFTPILHWIDGLAGPRPRPVTYPYGSRGPKELDPFVSKYGFKRASEGYVWPVVSLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYI2</accession>
    <name>A0ABQ8VYI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046969941" evidence="2">
        <location>
            <begin position="29"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="33367" checksum="AA50AC2523537568" modified="2025-10-08" version="1">MSPKRPVHFLLFIISSSWILSTFTHTYAVPMPSRLPPPYSDHSPSHSGLSEALSGPPPPSYSRDMVFRVLNDQKYARAWMISVYEHDPAVRVTSFDMTFYFTRTLSYKCKSPETRNARKSAICIAPDPHNKRAEVTIKVLQQFDRSALSEVSALKHFSYLLDSGLLKGKPTIITRKSPGVPLQKTDAWTKNPRQRENLREQVRTKWQMYIMNSSILTLPISDLHWENFLVEMTKDDQVKEVHIFNFEYPLLQVNFLNPYTTRSELEAWFNAYWDYRVDSGHWESDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYJ6</accession>
    <name>A0ABQ8VYJ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_751684</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="712" mass="81198" checksum="B0DF7E64AB91B882" modified="2025-10-08" version="1">MADASSSKPHSPEQPLEFRKKDGTYSKMRSHAGNIPVLPQTKLCPFCPAKFTRTTHLNRHLRNRKIIPQLCEAQFTRSDLLSRHRRGCNQTSEVRRKSCVSCAESKVKCDRELPCSKCSSRGIECVYAPVTKKVHRIHQLATTDFPEATRSKFSLSPVFGNTSSTIPNDPSDFSLAPTTTDITKSSRDSTSVTSTETSSHIPINSHLVSLYNCDVFEPFFSDVFSPTVDHSLQTPISETHLNERRGNKEYVWINFEPGQNNVSQGDTPTTTTSSASLHSAISDVTTEIAMGSLLEQEDNEKRHYLHLFYSGFVEQVPVVHAPSFSPEDKPPFLINAMQACGAIFVRSKTAAAFIATTLKSSRKVLSEELSRDLLTIEDQLNLILTVVLLHTLGMYHEDAEERAASSLYHGMLITMIRSTDFISHVASWSADEDNHLSLEEHWRHWAWHEMSKRILLLSYLQDASQCIYFTVPSSYHVAELNFNLPCDDKLWRAQSASEWWSELHRGSPYGDAHDRLNCPTLPSLLRLVFEPRTTQVKAISHFAHWAVIHGIISCLFALCTRGHLPVQRSFGANGDPLNQELYRIQFAMHNWLDWWMKRPEVIENTQEEAELPFMQNPLPFYWLGQVALMAFQENLPPFNDQANLSMKLRMEVRFWQVKKWIRHIRSFLAGARGHTPTILWDELMNIRLQSWQVSLEHPAKDDPHGLLGFFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYQ1</accession>
    <name>A0ABQ8VYQ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation initiation factor eIF2B subunit epsilon</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_892175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04197">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11558">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035543">
        <property type="entry name" value="eIF-2B_epsilon_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044123">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="W2" evidence="8">
        <location>
            <begin position="555"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="430"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="718"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="516"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="722"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="765" mass="84170" checksum="0DF7CBE6386CE10E" modified="2025-10-08" version="1">MAPKSTAGNEKLLDDQAEVLQAVILADSFNKRFRPLTTRKPRCLLPICNAPLLDWTLESLALAGVQEIFVICRSHPEQIKAKIAESRWSKPGSGIKIVPILTAKETFSPGDAMRDIYTRGLVTGDFVLVMGDLVSNIRIDEVVKVHKERRKTNKDAIMTMVVKESGAKHRTRSKADSAVFVLDSETSECLHFESMMGYPPSTMASIPREILATHPDVEIRNDFIDCSIDICSVEVPSLFQDNFDYLDIRRDFVHGVLTSDLLMKNIYCYVAKEGYAARVQDTKSYESISKDILSRWTFPLVPDNNHPAGHLYEHIRGNKYIDKDGTVILARTSTVGNKCLIGSSTRVSDNAQIISSVVGRDCFIGAGAIIDNSYIFSGTRIGPGCVIERSIIGYNVDIKENTRIDRGSLVGDGVIIGPNAHLKAFGRLSKKRETKTTGDESEADEYADSEEEEVESAQDSITVDLGTASNAIVWPPNAPDEDEDSEDVENVKNQRFMRLGDSASDLAFSDPGSESSGEESESSEEDSDFDKHVDNLPTSSATSLSLDPNDSSTDAIAESEFRNEVKLSLERAFAEGHSVDNAAVELKTLRMASNVPLSRVRESVVSAIVERIKIIDGGGVTQRQEIANVVSRWGPLINKIGGVDMVETVTALQAHCASSERLPLFGQILAALYQNDIIEEDDIREWHQAATSQGLGLSPSVRTDNIKKCWEIGSRMIQQFDEQSDDSENESGEEEGGTEDEDEEGGEESDSSADEDDEEEDEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ30</accession>
    <name>A0ABQ8VZ30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_912912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10910">
        <property type="entry name" value="PIN_limkain_b1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024768">
        <property type="entry name" value="Marf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379">
        <property type="entry name" value="LIMKAIN B LKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379:SF3">
        <property type="entry name" value="MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="14"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="428" mass="47101" checksum="D3EA68798FDAE7ED" modified="2025-10-08" version="1">MAPSMRTGSSAGQVAIFWDYDNCSPPTNISGYVLVSRIRDLAHEYGSVNLFKAYTHISEQTSPRSLALRSELQSSGVSLTDCPRNDRKDTVDQMIIADVLTFAMDNPSYPTTTTIMLISGERDFAYTLSILRLRMYRVVVVAPGLPGSQINLEAQASFFFDWYTIINGQQKGEKRNTILPSRPMESSTSSDRPRPHTTSTYFAKPPERHETFQSCSNLFEPKNAPAFAPFRSLISEVPSSITQTPVPATMVEKPANRFPILLNEDSPDIALIPLSQPSPIIVTDADSQKTIFSESEDTASVPASQSGKPINSSMTAVGSEINRSLARKQGPTTSRGFLGRTATPEVPEAYQRLIHLLEDYRLRGDQRPFRSAIALGLITQDPFIYQKAGYPKFGPFVTHAAELGLVKLGGTGGTAWISLHYSLHGKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZD3</accession>
    <name>A0ABQ8VZD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Actin cortical patch SUR7/pH-response regulator pali</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_862283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF3">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045828939" evidence="6">
        <location>
            <begin position="27"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="192" mass="20411" checksum="54F520ECD8DEC48E" modified="2025-10-08" version="1">MAAGPAIPGLLLVLAATILLIFVSVSSPTWEKISFLNVGSGDSITHYGVFGFTGSKTQIGYDFNPSELAFDSSKLNTEIIHNLTKVLILYPIAAGLAGLGVLFGLCGAAYHRAGTVLMLLATSLALIVTLVVWVIEMVLFGIARDRFRDQNIPAEFGNANWLGLGALVALALGVCASTCGVFGRYRKRRDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZJ3</accession>
    <name>A0ABQ8VZJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_16314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="24656" checksum="F1FA1E6EFFA56113" modified="2025-10-08" version="1">MQSSSSTDAPTGTPPSTPPSSLYPPTSSLRIPPEEELRTTDGKRFPHIVKLSALKDQSETPVIQHYVASHETQVLNLGVSSNSPNSPGFRMRILTSQVDGGSFEAAHRLYTDHRDFNNEQHGGIPLLTQKQLLASRDFMCGTGYDLLHRHRGARILITAPRDHCTDMISVLTYYLVYASENTVAMVLHEIDKHEGFMGIWKNTVSQYAVSFIQEVVDMRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZQ8</accession>
    <name>A0ABQ8VZQ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_748602</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="288"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4501819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="596" mass="65548" checksum="BE35228D1DAC92D4" modified="2025-10-08" version="1">MTSLSTSTTGAGKSVAPLNPDKAIRTQRANEYPHEVWFFLACLIALVAVSRLLSFDPEKSSSHSKAVVNFRNLPLALVNIFRVVAFRFTLDFGSYSLNLTEVVLTLMYMAALFTWTFINTTNVSGGKFDVSYWSNRAGALIASQIPLITALGTKNNIITFITGVSYEKLNYLHRMAARVVFVLVWVHAGTKVTDELEQTWLRCGILAASSLTSLCIISVRPVRSRAYEFFFYTHLVLVLLFLVGAYRHSEEFSYQTYVWPSFVIWGVDRIVRVFRLVVFNHSYFGFGSGAGTALDATTELLTPKCVRLTLKRPPHFKWAPGQVAYLITPGVSSLPFESHPFTIASYDSQMSLKEITSSAASTNSDLNSTPTTSSYWKELVFLINVQEGFTKRLGDIAAMKGSVKVYIDGPYGCSHNSNLHDTIVLIAGGTGVSHTLPILLDTIEGVQNGKSACKRVTFIWCIRDFRNINWISSVLAKALSITPDSLKVDVRIFVTGSNVPDLGYELPEATPSTSSNFPSLSSLAPFRMMQGRPSLATLLQEEAEETRGGSMWVTVCGSRSIANAVRKGLQFPVAGPSMLLRGGATVSLHVESFGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZS2</accession>
    <name>A0ABQ8VZS2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-P-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_17969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF11">
        <property type="entry name" value="LD23561P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="46275" checksum="08B54EB4DF8D348F" modified="2025-10-08" version="1">MADGSLKPNVLICGVNTYSRALAAFLVPLEGEPLVSHLRIVDKYSVVPATTYLGAEFPKVLAKPQVDYKQANLTVPSIVHSIFDPPEGKGPYDYVFDLTGEVRHDRTEMILINTTCNVARMLGQEAAERKVKAYVRFTLPFYETTSKGTHDEKDDPKPDGTIGIWWHETLRMLAAIEDLNLVILRVGFVYGPYVEFGDITSAITVGSVYGYLKKPMKSVWSPGKNPTNTLHVEDLAGAAWASAQWIARLGRKEADILAGESIIFRNDKSKVSQVEGMPPHDKKLIAPLFNLVDDSNSTLLSVGQTVTSFFGTTFDFFNLGERTMYKFMDDAVEDINEHHVGGWTQMIQSSNPPIPNTPLSAYMDKYALEKHIVAFSNTKIKEVIGYNLKRPQFNHDGIKEIVDKWKEEGSWPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0L9</accession>
    <name>A0ABQ8W0L9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein OS-9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_748726</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OS-9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047441243" description="Protein OS-9 homolog" evidence="9">
        <location>
            <begin position="21"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="10">
        <location>
            <begin position="157"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="425"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4501507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="471" mass="52424" checksum="CEBD50F933B23D20" modified="2025-10-08" version="1">MSKNLLVFALISSALNLIVARLHSLPEDPHAFPKFKVTFLNNLPVLNETAQKWLSQGIPGGELEFLNQPWEHATEEVPLSLGLKEIDGGFGESGSSSPVLPESHIPYSLEQMKMGPRDSYLCLVPRPLEFSSSTSDVDSDEEITPARSWSLLQPLSGTCLYHRQGWFTYSYCHNDQIRQFRELPQAHSHMPGDLYFAYSPLFSWESYTLGKAPPAPEPGADLTVAEQNAIEANLELARGAGSRYLVQRWGDGTICDKTGKGREVEVQFHCSMTMSDTILLVKETRTCAYVLVINTPRLCGEPGFRSQRDIVEQAQIRCREIVHTQSEEFHDVPETDYPQKIPRIKKALPPKSAEKLEKSSGGVSTENILLKTLEAFFGENSNGQVVVQQVTDDGEMVIEFLDDLSDNGDDGEDVADKITNVLRAAGYNIKGEEKNKQTSPGNSDKKRQDRSSDSSSSEEQAALQEQVRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0X3</accession>
    <name>A0ABQ8W0X3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_4733</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051274">
        <property type="entry name" value="3-5_Exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044">
        <property type="entry name" value="3'-5' EXONUCLEASE ERI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044:SF61">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="82"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="343" mass="39622" checksum="5567E4B4AB7F723E" modified="2025-10-08" version="1">MLRSTDLLTVIFTVALIFFFCFILYPGLRQTVDMQERFIVQEGSSNSSTADNRPVGDAQDNRDELNIQESARTRQPYDVFLVVDVEGTCEAGSSFDHPNEIIEFPVCLMRWKDDKQRHELVVVDEFRSFVKPSWRPTLSRFCKELTGINQSQVNNAPTFGQVLESVSQFLVKHGVLDEGCCEPLLRFCWCSDGPYDVRDFVVKQCFISKIDMPSWLKGDVLDVKKMVTSWSIMQNHRGRKMKAMLTRNYPNRPSLNISSQLRVLGLPAFQGRKHSGIDVAPFKFFMSHHSHTDSNLFFQDAWNISRIISECARRNIRLQPNTRIDPNRRWSWMGKSGQILLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0Y6</accession>
    <name>A0ABQ8W0Y6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">INO80 complex subunit B-like conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_432473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029523">
        <property type="entry name" value="INO80B/Ies2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006880">
        <property type="entry name" value="INO80B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561:SF12">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04795">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01406">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit B-like conserved region" evidence="2">
        <location>
            <begin position="208"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="517" mass="55893" checksum="5DC7B6A2A97A201E" modified="2025-10-08" version="1">MKKCRSLKRKKLTLMPTAMKKKTSMWRARCRTQLSEDEIKSIPVAEVDSDGEDDDVPRSPLKPRLKIKLKLPIVPASSTSNTATPVPEEQKVTPSRRAVAKRSAAVRGRRRIQDMESSSSEIETEDGESEPVEDEEDEEDDDMQVSVDNSSVTAHTLQGRSKSRSMTTRQAVLASVMDSSHIALDSDLAAQSVQGNTSKKKKVLNETELALRREENARKRKNLSEKRLEDEKLETINRLLKKQSRPRTKRAGGPSQAHSAGSSVPPAPVISSSTGNRGGKRGGARGGARGRGGRRGRPRAIADEEGGEAEVDAEGDAMEIDGQEGEGEEGVEGGNEVEGELREAPDGSTGGSDRSKGMRAPMMQAPMIPMFRWVSTTVLVPTEISTTVAKPLSPDQPIGVKTEGDIKMADAGNVPAQQQPPVEPDKTSLSSSPNDDTLAPVSVLESPSQERRMQFSLAIPAAFLPPENATPLPLTEIRPPAICAVSGCENSRKYRLVKDWKIGACGMAHLKVLEGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A810</accession>
    <name>A0A9W9A810_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial ATP synthase epsilon chain-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8J55DRAFT_561912</name>
        <name evidence="4" type="ORF">C8R41DRAFT_845634</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000020">
        <property type="protein sequence ID" value="KAJ4476491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A810"/>
    <dbReference type="OrthoDB" id="269124at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4476815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="74" mass="8233" checksum="10BC65B137CA6129" modified="2023-11-08" version="1">MSAATWRSTFTFNKYSQITAGAVRKSLKETQRLAAEKRGLTALRYQVWENGKGGEQITLDPTQESDPKNKTAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AXK9</accession>
    <name>A0A9W9AXK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_504255</name>
        <name evidence="8" type="ORF">C8R41DRAFT_925475</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000006">
        <property type="protein sequence ID" value="KAJ4491449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AXK9"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4468081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4491449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="216" mass="24363" checksum="328571346E60EE73" modified="2023-11-08" version="1">MPVGVEAWITQIPPITRGWLALSVLTSLAVQCQLVTPLQLYFSPKSAFINAQPWRVFTTFFYFGSISLDFVFHLFFFMRYSRMLEESSFANRKADYFWLLLLSSAMLLALSPLFNLPFLSSSLAFVPIYLWSRRHPDTPISLFGLFTITAPYLPIALVAFSWVLSGTWRAAAGDLAGCLVGHIGWFLRDVWAREMNGGTSVLSESPVALKRLFGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DQF3</accession>
    <name>A0A9W9DQF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mob1/phocein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_511810</name>
        <name evidence="3" type="ORF">C8R41DRAFT_910933</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DQF3"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.30:FF:000001">
        <property type="entry name" value="MOB kinase activator 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="218" mass="25309" checksum="6D0BAD0428E5E118" modified="2023-11-08" version="1">MSAFFGLGKTRTFKPRKDVPEGTKQYQLRKYAEATLGSGNLRLAVQLPDGEDLNEWLAVHAVDFFNHLNMLYGTVTEFCTRQECPIMSAGPRYEYLWEDGVKYKRPTKLPAPEYVDALMNWAQNLLEDEAVFPNKIGVPFPKNFRDTVRTIVRRLFRVYAHIYSNHFDHICALGIEAHLNTSYRHFFLFINEFDLVDKKELAPLDELNNAILAEDKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVY2</accession>
    <name>A0ABQ8UVY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_739309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000166">
        <property type="protein sequence ID" value="KAJ4463416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="90" mass="10716" checksum="A6CE4528D9E7D75C" modified="2025-10-08" version="1" fragment="single">ISNISDEQLDSLIGHLRIHFHQAGIRMLDGMLRRLNVMVPYERICQSLIHIDPIHRIFDRIRIRHRGYSVPGPNSLWHHDGHHREFLHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW14</accession>
    <name>A0ABQ8UW14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_155534</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000162">
        <property type="protein sequence ID" value="KAJ4463468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF65">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4463468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="542" mass="60528" checksum="F404B245444B9ACA" modified="2025-10-08" version="1">MSQLERGEQKRAGLNEDNVNEKTDSNVEIELAHGLSTLPNSIDETTRTTISALSEAESNPFFIPNLTFTPSEESKVIRILDTRLFPWVLLTTFVLNMDRTNLSNAISDNLPKDLGFTTNTVNLGTAIYSVLFSLACLGGAVVCKIVHPARWIPFSMFCWGLVTMSHALIRDKGGYLTVRCMIAVTEGGVIPATLIYLGSFYRSTELATRLAWFWGVQTIASAVSGLMASGLLQLQGVSGLEGWKWLFLVDGIITVVVAVLTWFYLPRNATLTKGGIRGWKPWFDERQVRIAVTRIVRDDPSKRLYEQRVHWEDVKDAATDLGLWGHLFITAVGLTPTNPLGVYLPSVIKTFDFSIFVANALTAPPYILQCCTTVLFIWHSDRIGERGFHGAFGATWQLVGWILLRCLPSDTSKGVKYFAALLVACWPYTHPLNIAWMSENTGSIGKRTLASGCVIFAANIYGVWGSQIYQAKDAPDYHTGNTINIVFAGTAVCLWFVQKGYYKYRNARNARVWVQLGEDVQKREEMLQEKEGNRSVLFRFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWW3</accession>
    <name>A0ABQ8UWW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein MON2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_782988</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000144">
        <property type="protein sequence ID" value="KAJ4464262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF333">
        <property type="entry name" value="PROTEIN MON2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="7">
        <location>
            <begin position="4"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="5">
        <location>
            <begin position="207"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="6">
        <location>
            <begin position="1118"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="6">
        <location>
            <begin position="1437"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="715"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1013"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="730"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1016"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4464262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1854" mass="202178" checksum="8698074EEEEE023A" modified="2025-10-08" version="1">MSSLAFLVTELQSLSSETRRKHPEIREAAEKSLTILRASPEQANINLTTDGPQSFDLLKPVFMGCATKSPKVVAISLGSLQRLISLKAVPKSTVPEIIRIMGDAMNQGVDIQLKILQTLLGLITNYLEVHDTLLGNALLLCFKLQESRIAVVSSTAAATLRQLVMVVMDKMVDEDHKNTDAEIGEAVNRLAEMTLPDGTTTPLSPSAKDAYSVFEDLCLLANSEKPNFLKLESLHKTFALELIESVLTNYHALFRKHPSLILLLQHHLCPLLLKALSDRPTFPLILRCTRVVFLLLKQFSLELQTEAEVFLMLLIRIITDDNSVSLDTSGSGSSIASNESYGHNHGSRPQWMRVLAMEIMRGLCSDAELMRSVWDRYDAQEHGSNALSTLITALKRLITEKPALLGVGSQMFGVGVSSNNDSHYALSPSGSAYSLDGVAGMVATAASATVSNVVGMMGSNAGLSLQGSTMKLQCIDQLDKADSPPIPESYVYLLAVQCLVSLCEGFATFAAPLYNSIIIQKPRTAGEAPIRAPPALDFTSLSSDDPLTKQLQIVRDIIESNWPALLAALSFVIATNLSDEIFVDILASYQAMTNVSGMLGLTTPRDAFFTSLAKFSVPTRVVSSLDSYTDTQTPRSAATSFSENLGLSLSGSTGFTSPGLSERNLACLKVLISSSMFLAGSLGESWFGILEVLQNADYVLTSKGIAYGAQTPGSKGGAFSPGRGGHTTPSRSVSMALSSSGSGLGLSSAAVSSSQQPSTRHPLLSDLDPEMMLSAIQRLFDASKNLEDGAFKFFTDALCKLSAEMIGMQTGTADGTSLEVIAETGSVEELSSLDGVVLSPPAPSIADTPHRRRVSGIHLPRTLRSGDFGINKLGGVISQNIHRLVYRPPEVAWTTITTHLLSVIRLPTAPPPIRLQAARVLDDILITVPRNLGTAGELQAQVQQRVLEVLSYQVIPDYTSLPGAATSNVGTTVELRRMGLETLHEILQVSGHTLIVGWETIFSMLESVCRPPPPTKSGSVDSTIASPTASPPRAKPTLLGLGVPSEKNYTTLIKIAFQSLNLVCDSVSELSPEHLRLCISTLGQFGRQANTNIALTAAASLLWSVSDAIQAKRKDAEKEPEYSALWMFLLLEVLGLCSDDRPEVRDGAIQTLFRTMQLYGASLSLQTWDECIWKVTFPLVDSLSTEIHRRSALVEPFDGEGAGEQAWDESKILAFNSIGSIFHDFLSSKLVHLESFHSAWDTFVTRIQDSVLLDNRSISTPALRCLEKAVKASSASVFDVRQKVVEMKERIWIAIDAVGSAILRRRNGAQSPSPDSAILPKPFTQECLVAFVDVIQSTRDLSRALEGAEWPLERLTRLMVILKGVLTYPNSPDYRPDIDALPPVQTVVMTTIGSIDLSGSGIPSLVLRDLSEFATLPFLAAFDIPPDPKSSTPSKRITYIALAKRTMPKLVELCLQFKDRLELYSEGTIEAVLSAYSIPVKLKYDCPSPSKHGKDPPLWKTATTCFLRIVKECAPQVIAFDEEISDERLEGIWRQIIDVFRGGILADCSTAESFPLDIQEEEENFDLSLVASLEIDIVPHLRGSRIPDSVFTQLAKVLALGSGLYDSSLSSSPSESEFGRNEYVHVGADQHYPHGSTDPGHSLPRERFSYWCFDLLFLICSNTTREQEHARKRLAALSLPALLKRCRTTMVQYVADEALRGNLPLPRAREDELLYVLRKLRELRLWPGSLWAALSDDPTKYSAEQPPLDPSADSKNTMPSSLTSKTLILDAVNRSSVGHLFKFYTLLCEIASVPRRTPEAWVHIRPASASIASRYSEEQDPKVEGRIDHQLEHLDARTLAKECLKIIGSEMGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX52</accession>
    <name>A0ABQ8UX52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_127595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000140">
        <property type="protein sequence ID" value="KAJ4464490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="82"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="260"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4464490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="454" mass="49707" checksum="A24FF05A50FD927D" modified="2025-10-08" version="1">MSAKLLDPLKSLVDIISTQTAVLQSAYSKNNTKAPSLDTTFQPNLSEFDPSVIAARHLIVAAATQLIATVQSPVEFLQSHAGRIYDTVTLGFVIDVNIPEILKEAGTQGLHVRQISSITGVESSYLARVLRYLATRHIFKEVSPDVFAHNRPSSMLTKAKSLRAIEEDPIGRFDNAAIPAFLHIASDELLNSSVPFTSFVKNPGQASAPFNIAYKTSKKMWEWMEESGNELSARKITAAMKDTGDAMYPPEIFTSGIDGDALETNGVVVDVGGGSGLVTLALKKAYPKLRYVIQDLEPTIAAAGKVWDEKDPEAVKIGQVQLQVHNFFTPQPIKDAAVYFLRLIIHDWPDEDARKILTHLRSAAGSHSKLILFEMLANHVTEDLSPGPTAPYPLLPNFGVVGAGFFTTLDMALLTMYNGKERTLEEYTQLGRESGWKLEEVKPGKLSALVFTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UX98</accession>
    <name>A0ABQ8UX98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_872069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000137">
        <property type="protein sequence ID" value="KAJ4464606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="350" mass="39451" checksum="888D057F52E6DA17" modified="2025-10-08" version="1">MDMNMEYEDPYITAAKRRVEEQQQAAMTTGVPLLSPTPTSTPTSPAGTEFVFHPGVTRSRSEFEAADDFPGFSVSGNHQAFTQDRAQELLNTRNLTPESIAEVQEFMRGTDAVESIFRVLLVVLQNQDMLRRTAQDYSYLLLLLPLVYAYKHEQLGQKVLDIMRELKIADLPPAHDTGRCKVVTAECGSAFTQCRHGIKDKIAASLKSKIDIATLTRQIIQGTKARPTLALYIRFAMLRHVYTETESTKQLQEAAVAAGETPPTNTKKKGRKYESALDDFWGLVDKKLEFYRTQVPDAATRFEVYNGIYKKDCELYPRAASMEADLTVREKDVEPWLQTLQARAQIALSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXH8</accession>
    <name>A0ABQ8UXH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">XLF-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000159">
        <property type="protein sequence ID" value="KAJ4463559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="34304" checksum="FA7550F8C61C1DEB" modified="2025-10-08" version="1">MSDSHAEKNLNFAATRHGWTRNFTITPEKVVTMSYATLESVLELNTLKIRAMSLRIFVEHPPASSNFVKIRPWKDDGTLQSILMKAFFEERMKAGVTTNLDIRDGNIRENDIGDGGKDGSGGIGAKEWLKAHGLTKPKSNNLNPSVAGESEEHDTEQTAAVIGGNGFFSAFGFGKTSVATPPKSDEDVSEVDNHSLKASEKGLKTEEDILRERGWGPPLMRRLTNRNLKSRKSQAPIEEKDIQEEGDGEEIEIPEAEEANGGARPKKNALWRKHKNNTFLGSGKKAKSGVEIIKTPSDALKPALSAPASPSKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXR5</accession>
    <name>A0ABQ8UXR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_782093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000130">
        <property type="protein sequence ID" value="KAJ4465129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="123" mass="14548" checksum="7AD06DD865B87E09" modified="2025-10-08" version="1">MEDKEEEERVVIANIREEQHSQYYHEPVAVPKHSSPFKDNGKEVKTFARLLQELESSDFIPSNYRLTPGEWETGIYPIFETIPFGKKGNRRLEVPLPPHIWLKRAIQWVRCLVIMDSIRDSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY78</accession>
    <name>A0ABQ8UY78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_95634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000123">
        <property type="protein sequence ID" value="KAJ4465714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="106" mass="11605" checksum="57DEF739CB9C25C8" modified="2025-10-08" version="1">MLETYLPDELGILLDLDLTLHGIWVPLVTKMVNAGCTGARKLVVGNHEANLSGGPPKQSSKAQFGVGPSVSEKLPTYANLTDVEFARLLQEETKRLNDQQKADKHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYY3</accession>
    <name>A0ABQ8UYY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_932499</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044970450" description="Carboxypeptidase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4466347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="499" mass="55046" checksum="E959A801CC579A3A" modified="2025-10-08" version="1">MLARTLALLALISGALASQVPLTPSLNVNASTSKTWTSQFFTPLESLSFVKDSGFSVLGHPFFPKHSVRIKKSDFCDSTVNAYTGYIDIEARHLFFYFFESRSDPDKDDVIFWTNGGPGCSSSLGLFMELGPCRVLDDDGPKFHPESWNTNANVFFIDQPIGVGFSYAEYGESVSTTEEAAKDVAAFVAIFFENFSRFKGRGFHMAGESYGGRYLPLFASAVYDQNSALIEAGITPINLTSVMIGNGMTDFYTMVTSYYDMTCTAASVDPILDIGSCVTMKKVIPRCQKWLRESCVDQYDTINCGAASNFCNTMLYSPFQATGMNPYDISVPCNGSIEETLCYPVTVSISNFLSQPPIRAQLGVDTHAEVPVNFSSCNSNVGAAFDGTQDILHSSQDYVAALLERGVRVLIYVGSYDWICNWVGNERWSRELEWSGQEEFASQELREWTVAGKKAGITRSARGGLFTFATVQGAGHMVPYDKPKEALALVQRWIAREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ86</accession>
    <name>A0ABQ8UZ86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_69127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="62053" checksum="026255C18BA85A08" modified="2025-10-08" version="1">MDATRDYVEQCDSVLGRLDAMRIAVEEQRDHLLLLSQTVDSIISPIYKLPLEILGEIFTNICCGDIGVNGLSGEGKRRYPTLELSRVCSKWRNMVISMPVLWTSLGIDMFCSLNAAYSFFKRFLGRSSFHPVDFTINYEDAYPYQGPHEAPIFPLLESNCGRWRHVCVRTSLTLVEALMQPIISSGKGLPRLESLSLNPRFHDHPDEGLLDFPVDCPNLRALKLVRHSLDLKFPRPTITSLKLAKMSPSEMARVIANCPNVQALKIKELTSLDTSLSPVYTKCNAKKLILCVGNSREGVAPDSMMKFVDLLILPELNHIILSDPRGALESRHVKSLCNNMIEHGYQNLTHLTLDRTFLTAEQLLQLFLSMSSITYLKTWKTAVNLALELLIAPGYRDQPGQHIGNNGGRKERENMLEGYNSNDDESEDREVDIGVDAIEVPEGKCLLPKLQNLELVLPYRLRGTLLLAFLRSRWKPLPQMEVSSPTLTEDHPQGLSDIGEKTCVSLQKLCLRYTYLDGERDLEKLQILQRSLDPFRSEGMDIEVLSEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0X2</accession>
    <name>A0ABQ8V0X2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_854115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="60647" checksum="052EE8970A6C3FC4" modified="2025-10-08" version="1">MSTEERVKKLKEEGNNLFAQKQYVAAAEKYTEALQLGGDNAVLYSNRVACRLKMKTYLDAESDATKATEIDPGFSKAYARLATAQDALRQPYRSIPSWKKSLDKLPKEGLTPAQRNQREDEYEKGLTLAESALNELRTSGGSHLIHAPSNQRDLPWFCAQRMIPDLMEQRNYTSSAWALANAYTEFTEGIRQLSLATTQGQLRFQSTSALMLISNAILTDHRVFHINGPEFLQKYNQQVLGEAQFFKAWTHEGPDIIKQKVLERLEEEGWHTTSPALTTTIRAWIMQGFYQGGLYQNHVAEVEFLGRTIEIIKWGRERFKDIRKEYRGVMFEETFLRGVQMLHLEALLKVIAKADDATLEATLQEANEVIAGVNAATIPPRDSHPAFVSAYYYKPKGQALSLKAMYNRVQANRMKAQNGSLSSSVMDKYFSASRYYLEAADCYAEDDENHAVFLNAGLEMMWSCKTSIRNQLAVMERIRLAIPKMKIWGQSSFAKQGGDIIFKRGQDIEGILREGLNKRRYQLDELIVLDAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V167</accession>
    <name>A0ABQ8V167_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_971411</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="405"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="417"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4468988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="488" mass="52770" checksum="3E6617A374D28736" modified="2025-10-08" version="1">MQGWRITMEDSHAIVLDLDDDKQERNAFFAVYDGHGGGTVAKFAGQNVHKRLVTEESYQSKAYDAALKRAFLGTDEDIRASPVHARDPSGCTAVAALVTKDKIYVANAGDSRSVLSVKGEVKPLSFDHKPTNESEKSRISGAGGYVEYGRVNGNLALSRAIGDFEFKKNPHLPPERQIITSDPEITVHNIDPEDEFLILACDGIWDCLSSQQAVNFVRSKVAEGKELSEIGEMMCEHCLAPDTSAGAGIGCDNMTVLIVALLHGRTKEEWYTWIKNRVDNKYGFDTPSVLPQLYAQSRLTAFKARREALQAREASLLEYEEQPSFLSPGLSFTRVLGSTGGISFNRESGILSSASSLMFTGDDSDDEDDGEDSTSSFFTETLGLGATLHEEDDDGLDATQNLKAKLEEFEKDIQQDGSDDSPDSDSTTDGDTSHPKLQGEAPPPPTPQANGGPVTPAPQLKSEPGGDKASPVVAAEGLMDTSEDPLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1A7</accession>
    <name>A0ABQ8V1A7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_926178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046183362" evidence="2">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="262" mass="29550" checksum="FC482CE369DB2EC7" modified="2025-10-08" version="1">MLSSIVFLASYVTLSTLSSASPVPSFDSASSPSSGSNSTLIISGPFSSIPIVSRGNEQSTPGDRTTKKHRDNRNHRKKGIRWPQDIAYVNQLLRQGHEIFGYSFVPVDVEVPSLSDLQIPALQSTFQGSTGRLEHLFRVPPYSIRGCRSCIIVSQPSVRQRLKTQYGMVFHLIPPYNPSTSIEFSETDQRFDFVDNTQDHTVMYLPQPAIDEEKQNFHIACYHIGRNSGPPSTWIGANWAGWGIENWQDWDYNRQLPPQYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V279</accession>
    <name>A0ABQ8V279_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_632207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="149" mass="16874" checksum="74140EA90A4AB42A" modified="2025-10-08" version="1">MKFSRFLFVLRDGRELSDEHITIIDQHLRFEVEHLTAPTYNSKDAHSSPLSPPSFSITHSSISCQHVGFASSTFRRRIGFMHAIDLLSIIGVGFLAATASGVAALLRRHDQQKRIETDIPRSLQLDYLHEHPNGDDTEQLFDYIKSKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2E8</accession>
    <name>A0ABQ8V2E8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_984241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000090">
        <property type="protein sequence ID" value="KAJ4470726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="373" mass="42144" checksum="F031CB5F362143A5" modified="2025-10-08" version="1">MPCSIPSIPLANIDELNELWEADERLPTLSSRREWSIARNLHPTAVNEWWWARRRQARDRGVGLSCENYHLSVGNPPDTVLIKIEPVDEDLPISPDASRCSSPSNDTLSVSHDLSSEDCNLSSQLLFSEKSEPGSPQTSLAPSSDQNDSKNMDICAHTRNEDLVLVTEALPSCGLHLPPELLQIHQPPAASFTEDTSEDDEVMLVDESSILRPLRSWQRKLWSTSTSIPQHSESVSLSCYSFLSLDGKTFTPNGSYSTQAADSEDHNIHIIKTTTQPYEFPLLSEWSDSDYLPHLPPTEAEPIESESPPECPLFASTHTWYRRHVDSPQYDTIIDTDLELDTDTLEYHAFSKHLYLQWTGDEGWLMRKELYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2J6</accession>
    <name>A0ABQ8V2J6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="520" mass="58412" checksum="E084E327680CACFE" modified="2025-10-08" version="1">MSNADEELLKSLAKLLGIYNYESDEFDENEVRMRLATGLHCNSTDLDNYLFHQSNSDIPHLQCTEEGKFKDRPSEIIKIGVAFYLIKWTRELIKSPSSVPNRPPNDAFLMHSFWRLLFRKKPRYPVGEFKKAPPNFQICMKALSETLQNLHREIYPNYRYDHRNTATKQKRSRRAEGHIPSPTPLPTIRSNPKSKPRKPFCSILFPLYLPDVKSLLPGPQKRPSRAVRGVSSSQDTMISTMQATSSNYRRNKWPVVDGTQSDISAYHSAPQSSSSFLGEFSHPPTLPPYSSRFPLYPDAQSAISSTYTPPSFSQSTMTYPSLYASGSSTSFRDPSIGDICPTAQWPSEPNPYYPYNEHGSDMYQSRYSKQGIPSSSYSSGTLFEEGSSSSISQRATELSGLSSQGASLFRSNSSWPSQEFLSESQPLGLFCSDLSAEPSQAYHEPNELPQNYPTQMIPDVLHPPLPQATSQSNLLSPLAELTHQVPTGSNNDISVLPSFEMDYPICFSEADLRILDSLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V361</accession>
    <name>A0ABQ8V361_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_850371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000085">
        <property type="protein sequence ID" value="KAJ4471917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046183026" description="Protein kinase domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="34234" checksum="E3FA0192587C4F86" modified="2025-10-08" version="1">MILSATLCCSLPIIFASLYMLAITPTSYAAPSIFPPQNHATPSSSDHEFSIARDSPRILTRAPLDIETRPYYRKWMIDFYPLEVTAENKKFYFQNGTFDNYLGRNLVDDWDNSANRGGYNAGVYTFTGPKRTYLGGHPPNQLVVKVLRQDQLDKWAYGEVMALELAGLYVASGKKSKNQIFAVFMKNRKSRPAIIMKKVQGMSLLKTTVWRRADPAMKISLKNAVKEIIKVQVVDFAVQHGILHNDFHTGNVFVDLSQDGTVRGAKLIDYGYPGMISIRSTNRKVLEKYFEWRWAKLWDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4I1</accession>
    <name>A0ABQ8V4I1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate-rich WD repeat-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_776149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051972">
        <property type="entry name" value="Glutamate-rich_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903:SF1">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="6">
        <location>
            <begin position="33"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="250"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="296"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="349"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00040876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4472690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="443" mass="48917" checksum="135D33184BC53E93" modified="2025-10-08" version="1">MDVDELMPAIEESEQPSATPDVFIPGTHTLGEDEILEPDESVYLMRHSTGVDWPCLSFDILRDNLGEERQRFPHTVWIVTGTQADLAKNNEIVVYKMSSLHKTQKNGDDSDSEDDEEDDALDEDPIIEHRSVPHFGGVNRIRAQPLPASEPLPPPTQPYHVASWAETGKIHIWDIRPLIESLETPGYSFDKLRSSKPVFTIDAHGRAEGFAMDWAASSASSIRLLTGDINSQIFLTTSTVSGFSVLPQPFTSHTSSVEDIQWSPSEPTVFASCSADRTVQIWDVRSKGRKSVAGIDPAHESDVNVISWNKGTSYLLVSGGDEGAIKVWDLRNVQKKGTSTPTPAPIASFHWHKGPITSLEWHPSDLSTFAASSADGIVSLWDLAVEHDDDEMNETLDTKDIPPQMLFNHHQKDVKEIHWHPQIPGAVVSTGAEGFDVFSTIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4L5</accession>
    <name>A0ABQ8V4L5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Argonaute-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_924269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="2">
        <location>
            <begin position="265"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="3">
        <location>
            <begin position="561"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4472735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="962" mass="105656" checksum="EDFF35B4FAEC5552" modified="2025-10-08" version="1">MPPRSTQQSGPARGGRGGSRGGGRPPRAGPPQIVGRGAQMTGGGGQPSGLPSALVKTVGVQRKGFGTLGRKIQVFTNACEAMVPEGLIYHYDAIVTEKTMPPRVAHQLIKQLQVQPEFHPPGAYDGKKNLYMTHLIDFGGPDSRDYNVAMNGNSQPRDRPPRIFKIRLTKVAVLNPEGLQRFIDGQQSFSEADQATLGALNIVIRMLPMQTHPYNSRSFFTDTEIKNVGHGFQLRRGYFQSLRPAIGRLLLNIDLSTGMFYKDGSVIDIALEVVGNRDPNALSMERGLPNSVFRDLERYLKNVRVSVRPAAAGSPPHIVTISSLTREGASRIIFPQRDGTSTNVAAYFRQLSGRPLQYPNIICAKTAKGAVLPFERCTIVPGQLARMQIPPEVTREMVEFSTKRPEDRLQSIRNGFRVLAYGQSEYVRSFGLSINEQTFPMTIEARQLPPPQLLYGQGSKDKVSKPRDGAWNMIDKKLYKPESINRWAMVVFDTRTRQDTALSVVRSFIDGCLSVGINVVERDPVIEYASGQGGIQQVATVLKAAGMKCVKKNNVGKGPDMLLIILPDGGNDIYRAVKHFGDVTQGVVTQCLKASKCNRAKLQYWANVCLKLNAKLGGINVVPDAAASAHLSDLQNPTIIMGADVMHPAPGSDAPSFSAVVGSVDSLGVKYIPRTHAQTSRLEIIADLHTMVKDILASFTSYQLNVEKKLPQFCKPKRLLFFRDGVSEGQFGQVMEQEVAVLKKVCQELGIAPKITFIIVGKRHHYRFFPRDPNARGEADKSGNCLAGTVVDTGIAHPLEFDFYLQSHGGLLGTSRSAHYSVLYDDNNFSPDALQSVAYLLCYIYARSTRSVSIPAPVYCTSFSPSLLNPYPFPNTFTPLATHTHTHPPPDADIVCSRAKIHYDPSGVDLSDAASTVATENLQSFIDGFKPLHGLHKTKMYFMVSGLFGLRINFYFYLPSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4N5</accession>
    <name>A0ABQ8V4N5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbon-nitrogen hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_587527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039703">
        <property type="entry name" value="Nta1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750:SF26">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4472754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="34165" checksum="914798308206723C" modified="2025-10-08" version="1">MASSIPLRIAVVQFSPKIGQVQVNVARARELCRQLKPRSIDLVCLPEMIMSDASAISPFLEHPKKGPTSQFCSELAGRLKCYVFAGYPERLTDEEASLSKEESTSEGGNSRKVGANSAVLYGPNGEWVGHYRKTNLFVTDKSWAKPGTGFATFLLPSPLRTLTFGICNDLNVSDSDTWTTEDGPYEIANYALSHNANILVLLNAWLDSGKEEVEDTDWYTLNYWAARLRPLWVNNLAGSNTGEIVEEDNENANGKEMIVVVCNRTGEENGKTFAGSSAIYSMRQGSGRPKLLDMMGRKEEGLRVWNILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Z2</accession>
    <name>A0ABQ8V4Z2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sec63 Brl domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_800601</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
        <property type="entry name" value="SEC63 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF0">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="11">
        <location>
            <begin position="100"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="599"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4474549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="661" mass="73828" checksum="43513D0ECB7BB728" modified="2025-10-08" version="1">MANYSYDEGGNMAAYFIITFLALILIPLTLSISTSHKKTLDGCQCSLCGEQRLRIAKREKGSIFTPRFSAKTIFIIGGWAVFAFLSYKVANAKMDNKVYDPFEILGLSISATEKEIKSHYKKLSKIYHPDKVKASVNQTIEEIQNKFVDLTKAYKSLTDESIRENLRKYGNPDGPQQTSVGIALPKWIVESKNNVWVLGVYGLIFGGALPTLVGRWWFGSRQKTKDGVKTSSAAAFFKSLKEDSTMDDVVGTLGQAYKWEFRSNTKTEDAAELNRLEKNIALTAPKQWETLRIVIDAGKNANQRKATILLYAHLLRLNVEQPNLQKEQTRILLQTPVLLNALLNISISRNWLIPTIYVMRLHAYLAQALLPRASLAKQDRVSQLPGITGEDTLKADDLAGVVDELERNGDSRAEDVKKAIARWGRLELVDAAYKVIGERIVVPSSIVYLTVKLRLVPPSSSSPVISEKALSVEEVKRSIKANDQKDEEFLMGRNDAEPIEGEGAWAHAPYWPENRKPGWWLILADDKNSRVVVPPMKITNVPFSNPTAGDRNYRTYKLQFQAPQAPGMYTWKIYLVSDTFVGEEVSRNMTLKIDDLSALNADEQPSEDEISDPDEDSLAGQMTAMRGGKVKKGAPRDEESDEESSTDDDQESGDDSSSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V522</accession>
    <name>A0ABQ8V522_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_898049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4469009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052115">
        <property type="entry name" value="NEXT_complex_subunit_ZCCHC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13316:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13316">
        <property type="entry name" value="ZINC FINGER, CCHC DOMAIN CONTAINING 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4469009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="421" mass="47455" checksum="03F551BBF3DB4555" modified="2025-10-08" version="1">MRFIRTLTTASGRLPRFTLYSGPACSLCDTAKEELAKVRQDREFHLEIVNIQDPGQEKWKRKYVYWIPALHLEGKEIAKGRWDAQINGSDYSEFFSALPSEHLFFTDTSLAYEDNPSNSGIYRRNSHDVLGANPETQNEIRSVTPHCFNCGSSSHMVNACPEQVNRALVSLSRQMNEFYRDLFSLDRIGGEFSARIYSVEEWKSVRLDWINSFNPGEIKGHDLRQALGIMPAEADSQAQDEWLQNMAVWGYPPGWISRWDPKELMKERVFSQCIENPQESEESFHIFGEEGNSETVLGQLKDPRKLLNSSLNQTPKRWAFYPPLRFSSSLLPVYNSVALPPVESESQKSYYVPFSAVLPAPPPPLGSPPSPPPPPPIELPPPLPPSPPPPTPPPLPSTASLSALRPKTEAEDSDMDLSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V568</accession>
    <name>A0ABQ8V568_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_561640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="314" mass="33555" checksum="92E31A216E0C238B" modified="2025-10-08" version="1">MSNAERVSLHLSVNLSGRNSHFISVHVASLSGPIAILPSQKVSNETSQSIAVELERRFLSSRKVEAPSCRNLTKDDFEKLPGASKLKATATERWGKHFSVKLNDPKEPQYPAEVCVKPTTVKFTGKPECHVTNATTGGELTGTTGTSALGIAQGTTTSGQFTISSAASISLSSSFMTSVSFPAITDIMDATTVNVGITNTQTTSFTTTYTSTTTMTLTMSSPEGESCNASQTMKLCTIQAIGEVVLYARGFVGFDYGSAVTDKTEKTKKGEKNEEHYKWFLPFDSLSEADISSTATFQGSTTSNIHGKYQGNCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V599</accession>
    <name>A0ABQ8V599_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_888880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="159"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="437" mass="50747" checksum="353DD71392B061CF" modified="2025-10-08" version="1" fragment="single">MKKEVMGDQPIQIVDRRPEFWTVYPWQRQILRLDQQVPLRFPANDLLWSLVDLYFIHVHPFLPLLHRPTFIRAVSDQLHIQDHGFGSVVLCVCAIASRFSQDPRNYPEGITSENSLGWPWYQQVSQVEAVDVEPPTLYQLQHCCLSAIYLKGTSMFHSTWGVIGLGIRFAQEMGVHRKQKGQLMTVQSELWRRAFWVLLGLDVLVSINFGRPRATTDDDFDLEPPIECDDEYWENENPAQAFIQPPGVPSTTSFFICYAKLLEIAGLGHRMLFSARKLHIWKKIVAGGSNWEHKVVTELNSALNQWMSCIPEHLKWDPNREDGLFHRQSCILYCFYYWTQIQIHKQFIPRSNEPSMLKFPSLAICANASRSVIRVLEVIERLKFEILPNFTSPVYVAAIVLLMNVWRNKYSLIPQDTSKDMDDVRHSLKATANYEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5A1</accession>
    <name>A0ABQ8V5A1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_71954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045364875" evidence="1">
        <location>
            <begin position="23"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="118" mass="12160" checksum="489366015D75BF85" modified="2025-10-08" version="1">MFFVRLSSFLVTLLVVCRAASARPLWSSRALKPRQSTLNVATCTDPATQLVEHDCNVALLGLGLFQLGGGIAGAIEFLRVNDSTTSATSGTCTVTATAVDGGTTIDISKGRLEGSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V686</accession>
    <name>A0ABQ8V686_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_846375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047009590" evidence="1">
        <location>
            <begin position="23"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="129" mass="14157" checksum="5B7FB9D8E084EEFD" modified="2025-10-08" version="1">MLSPLSLLCALFLAPTFLQAIAAPPFTPRPPANYFDIRIKESQSQHPLIVFGLGTAFKPASDPTKESPVSIGIKIGANDYRGYLIGNLTFNQNVSKDMVYTDLQTGTDIDPASSYAEYILNVVSYLRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6L8</accession>
    <name>A0ABQ8V6L8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_775713</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11651">
        <property type="entry name" value="YPK1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="27"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="248"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="11">
        <location>
            <begin position="508"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="617"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="664"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="619"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="630"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="669"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4473558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="718" mass="79886" checksum="C8E35D6110A24439" modified="2025-10-08" version="1">MQLPPPPARDKSRPSPNKSSATSSSATQASPMITSSAPKEASTPISRGQIHVKLIQARGLNVRSLAAQPYVVVQFEQNEFVSRNPTDETDKEVKGTATNLSLSRPSSSNAINALAAVDAAVKRRSGGSSGSKDNSPVSSVGSKTSALNGGLFGRLSAHNPVWKHEVSFDVTNSNSLITFNVYDRAVEDQGFLGTLQIKPILVHDHTVDQWYKLKPFENDTNEPVTGEMRVQITFEQYKTKRALTPRDFEFLKLIGRGTFGKVFQVRKRDTKRIYAMKVLSKKEIVAKKEVAHTIGERQILQRSLESPFLVGLKFSFQTEHDLYLVTDFKSGGELFWHLQRETRFSEERARFYVAELILALEHLHKYDIVYRDLKPENILLDATGHVALCDFGLSKANLRADELTTTFCGTTEYLAPEILLDEHGYSKIVDFWSLGVLLFEMCCGWSPFYAEDTQQMYKNICFGKIRFPKGVINEDGKQFVKELLNRNPKKRLGASRDAAELKEHPFFKSIDFNLLAQKKVTPPFKPVVESDESTSNFDPEFTEKSIADVGLNEDDYADFAEDDPSESWVSQSLGASSFLPGGHVHNGPLGSEKTGKTPPMTPISPMTTMTTLLNGTAHTTHKSTKHKSSRSGGTPLTNSVQENFRGFTYSGGESVSSHADIFTSRKVEDDDNDEDYVDVDEEPEGGTEDEFEDFGKSAGRYANLRKKGMGFTDLDDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6R1</accession>
    <name>A0ABQ8V6R1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_924540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4471660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="336" mass="37359" checksum="880F6AFBCD18ECE5" modified="2025-10-08" version="1">MPKYPSRSASFIITFLAATSNFAVAFQVLAAWRSLKWEQASEWETSSDKWKFDGLQAVWGLLLAYFSAASVVSAVGFAGVMKSKPTLVKFYRDYSIADFSFCAFITLIIGYNIFQPTLPLGVCEGLSQHPDLMRDMAELGLSSENCERWFKRSSLVFLAVMLVILVARLHFLLAVGIYHSHLSRHHSQRTPVANSTQLTHTRSPSRSRPMQRVLLLPQSVPGITSFPLSSQSSSNIEPSANDVEEVVMYAPLPLRSLPEDMARNLRQNAVETWITSPKTDEKASRSSHTHRHRHHHSRAHHESALNGSGQISLPIHPDEGLLPSYNSGSVSSSAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V728</accession>
    <name>A0ABQ8V728_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_984584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000099">
        <property type="protein sequence ID" value="KAJ4468929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="22857" checksum="708398F712542E40" modified="2025-10-08" version="1">MRNVEKQLDKASKLGFGRKRRTSKADRQARVAAAHAARRKQRLPPSPSRADNDEERKRPSHPLSRVDSDEEKCNSEKLVAEIAELEKTVDNLRKKSGYWKAKTMELREKKKRLEEEMKRNEEESKKRKRKAEEEEREMSKKVEDLEKELEREKKLHKMELAEHEATCVELEGTYNTLRLQFDPIFERLRPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7Q0</accession>
    <name>A0ABQ8V7Q0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="23857" checksum="28F6D32A181A803C" modified="2025-10-08" version="1">MKTATITQGPYNPAPTHETASHEQYKHYPSPGPSNGPLLPGTNSAPNRGSASEQRASRPSFSLNHAHMPFSGTTPASNHDPEQRNRPSSSSQSSILFSSSHAHTPFKGPAPAPNHDPEQRNHPSSGLSSIPFSPSYAQTPFRGPTPAPSYGPEPGHHPSSSGQPSVPFSLSHATPAPNHESASDQHNQPSSSGQLSSSHVRTQLPSQAPPLGPGNKTSSSSACAPSSAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V803</accession>
    <name>A0ABQ8V803_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_886540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="2">
        <location>
            <begin position="131"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="668" mass="71994" checksum="18F83792D7BA238F" modified="2025-10-08" version="1">MNWFSSLFSQGSSQSSRRGQAMSSTHEAFSIPTSSPIFASHSDAFTPDVLNTPDTSRSASYTYPPPSPAAYSYSSTFTNSRPNSLLPTHHDQFHTPILPRSAYPPLTQTWNRLRAWLTREYPELGDTLNYGILPQDLAQIELQFGFPLPAVVRESYLVVDGQEAESAAGCAEGLFFGLFLLPLEDVLEEWRFWREVDDDPNTGANAQLRDAMQSIPPNWIRREYSQRGWIPLVADKTGNYVGIDLNPGDSGTSGQVIVFGRDFDTKVVLFNGDGPAGWARWLATFVEELESGEGFEIGKGEDNSDDEDDVGYASYYNDGSGSGDGGGDNGLGGGLRLTGEYKGWSVLEAWADKSVRKWYEAGVIKDTVDEKKGKMAEKVPSLHLSQGAAAEVPIPVLDDVDSVEATDLRPDSVAPPANLTSPTTMNSRRPPNLPTIHITKPPLPLPVELPTPRDIVALPSPPDSRHSSFDEDLESGRARNMSEFPTDNIAVSRRVSPVDAAITVTSPPSPPPEDLLADSDSVLETTPIIQAAALSSPDSTEAVQHEPPKPEPLIDASSDITPLPEERVDDIEDAIDPDVTIRLVGGGGSSGDVAELAKEEIILDEADVDADVASLASTTSMASESSPSKEKKHKKTRSGLAGLKKLGLGKKKKGSVSSVKEAVADSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8D1</accession>
    <name>A0ABQ8V8D1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="22886" checksum="60EE5D33C30595D9" modified="2025-10-08" version="1">MPHHHGEGPGGPDGSGGFGGPGGFEGHNGSDRGFGGGHHHGGFGGPGGFGGGPQGGFGGGPGGGGFPGDQNGGFFGGPGGHHNHHGQGGFGGGNPGFGGFGGGYGGPGRQGGPGYRSGYGMPPHHSSHNSLLGKLVNKLEGGGNYQHHNGVSGLIPHVPNLFGNNHSHHQPPPGYGGPGSNRDMAFGQGPPQQGRSGFMSPPPPQFGGGGGFMPQGPSQGPGGPGGPGGAQTDGPPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8M4</accession>
    <name>A0ABQ8V8M4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_495763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="10"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="413" mass="46411" checksum="C38CCF8D58C89CD3" modified="2025-10-08" version="1">MLYNAYKVRPYRVELFGSTLYGVSTPNSDLDMVILDPNRPQGQKIQKVAPIYAIRNLAKNFQRAGFTRVVAIPKAKVPIVKFHDPATGLDGDINANDRLGLFNSRMIRHYCDIQPLLQPMLAFIKSWASPLGLNKPGIVDGPPTFSSYAFALMTIAFLQNIRLLPNLQDFTNTPVDSEQVFIHQNKPCHIQFRRIAPGAWLPPATLTLQEALYGWFKFWGTEYQYSVSRVDIRAGYYDVPPPSTTSSTTLNPEDKLRSKDLKVRLIDPFTHANVTDHIPAKAIETFRTECLHIMNLILPRSGPDPMSMSTTTPSPSSSSPPSFPPPTPPPSYPNTVDVKLARLRRLIREPALEVRIRSRFQKVKKYSKTSKGKKHTHPHPQSQKGALGSLEDLRRKLEGNSPNGKPQDQPRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8S5</accession>
    <name>A0ABQ8V8S5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046739442" evidence="1">
        <location>
            <begin position="24"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="218" mass="25464" checksum="145CCDC9D42C26CB" modified="2025-10-08" version="1">MLPFSRPIYPVLFLVVFLAGAIAFPMVPRTGQLRQPRMQVVRFGFVRYHHSPVTNQWTILHTQEGRYAPFELQPWSVEHVETERWYLNIHGLGFTTEKQGDQWARISHSFEPTDGITLLEVNVEAANYNTVARQLLLMVDTINENQPPVLFIKDLTIQYGHHFQSTGMFNVYWPYMERMIVRRGTGSLSVLPYQDPEVRIYEELLQNQTTPHGSKYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V973</accession>
    <name>A0ABQ8V973_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_842400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="8"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="349" mass="37993" checksum="96FA0D598970490D" modified="2025-10-08" version="1">MQAILKVGEGKVALKTVEVPKPGPGQVLVKIFAAAQNPSDWMKLKRGWGEGEGLIVGHDFAGVIQQLGPNVSESTRSSRQIGQRVAGFVNGCMTPENGGSFTEYCVADEMMLIDLPDDMSFESASTIGFAAFTACQALWQNQTLPTPFDATKNPFPILVWSGASAVGQYAVQLAKQSGLQVITTASSRNHELLKKLGADAVFDYRDNEVVSKITTFCGDNGLNVAIDCASNDESISLIAQCIGDRKESYIALVLPVEVKAKHIRSDFTYVYTLLGKPTKDKYNYPAIPEHYVLGKWCAGLLSHLVKQGTLSTVPIRVVPNGLADAQYWINYQEEGKVRAEKIVYRVHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V990</accession>
    <name>A0ABQ8V990_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitinase</fullName>
            <ecNumber evidence="2">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_471046</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00598">
        <property type="entry name" value="GH18_chitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF49">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045598102" description="chitinase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="48"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4481794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="328" mass="34980" checksum="271C3C936BB43EDA" modified="2025-10-08" version="1">MLAFFVLAVLGLSWMNHGVLCSPVKSAHVHGNSTSEVSILPNGTLVSPHWVIYSDRGVSGLSGPPPVSQIEGFNVFALAFLLVAGAFDQAAEWTQLTSAQRATIKAQYAAAGIKLIVSVFGSTDAPTTNGADPIATADTMAAWVIQYGLDGVDVDYEDFDAINAGDGKAEAWLASFTRRLRVKLPREDYLLTHAPVAPWFSPGKFGGGAYLTVDSTVGSLIDWYNVQFYNQGANEYTTCAGLLTNSSSTWPESALFQIADSGIPLHKLVIGKPALTSDASNGFMNTSTLANCLNTAKKSGWNAGAMVWEFPDANSSWITSVRRLSFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAE8</accession>
    <name>A0ABQ8VAE8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_771473</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF885">
        <property type="entry name" value="2OG-FE(II) OXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="190"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4480323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="383" mass="43438" checksum="15804A77D7AB7EF9" modified="2025-10-08" version="1">MVEISTPISRSTDASKLDYYEIPVIDWQLSDKDKPLFLRQLRDAMINIGFLYLANHPVPHEVIAQVKKIAPKFFELPQESKDMLDMKNSMHFHGYLKVSGATLSNDASVREQFNFGGARTCSWKEGEPEYFKLHGEALWPSEQDLPEFRNTMLTYYNHVEDLSYKFTRLVSEALGLGPDALDVLFDQDHGNLQPRCKVLRYPGTPDGQPGSGIAAHVDGSFLTYLLQATDHRTLEVKNLSGEWIPVPPKENTFVINLGKTLEKATRRVLPATPHRVLSPIGAPRFSVAFFSSIGHEVRLAEHYFPFPEEVLEMKYARDKKLGVDSNFGFSEKDMDLAGEVVLARKLRSHADVTERFYPNLFSKYYPNGRPAKPNTGRNLMSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAL8</accession>
    <name>A0ABQ8VAL8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_450540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000054">
        <property type="protein sequence ID" value="KAJ4484475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4484475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="593" mass="67830" checksum="139D958B427B9FAD" modified="2025-10-08" version="1">MTTTPPASKELKYMFAHIEGDKLVKHPDNPKFDYGGPGDYLDSFIAPIRKQRSQIHRKWVLLVPETPIIYAPSATLWDRVAECPPVEYKTGYWRVWESGPLPAPIPPIDPVSISVLLVPRSQYAQLNEKRDKLTDLRVKNIFQRPQKAPSKGATASTFINDHKYNPIAIGRPKQDDFYHVPISLFHAEFAQFKEDIVSGALDQELSPLAYRWLKELSGFFEDENNRESKFNELLSDLLDGYKVVKKKIGSFESGGGIDPKDLDLPDLLVKPLLVEVKIEFTQGSCDAVFEIVLCDQEGVRLILSNDKYKGDWRKTRIPSVLVIHNGPNIQALGAVYLTDQYVEVLSPSLPLYFSEYDTHSMENLLRFMTALRNLFRSLLKVYEKPNDYAIDSDQVSFPYPRSYRSSGTTVRFTYIKRVSQIRLVFTARTEGDQDIIVKFGYGPYGVEAHQAAAESGFAPALLNHSNLAGGWWMVVMENLESDFQPCDDFDILEPPCKDAITECVSKFHTMGFVHGDLRDTNVFVRRKQDRWQCQLIDYDWAGREGKVVYPIGVYGTHSVWRPELHLDGQMITSEHDNSTVNEFLRRRTKIIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB11</accession>
    <name>A0ABQ8VB11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GC-rich sequence DNA-binding factor-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_769088</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFP11/STIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022783">
        <property type="entry name" value="GCFC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022159">
        <property type="entry name" value="STIP/TFIP11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07842">
        <property type="entry name" value="GCFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12457">
        <property type="entry name" value="TIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="259"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="863"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="100"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4484628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="974" mass="109704" checksum="794D5CD7B15FFFD9" modified="2025-10-08" version="1">MARRKRILEDDDDSDSYNGSEAEDLPMNESADVREERELFENPYQRKRRKRNGKEEALYGIFAEDIDEETSGGSRDPKKNKRSDWTKAPAFVSGAKKIDVEEETGSNIEKDEEEYENEHAEEEESSEGEGEGEGAEESSDNDSDPSRRPSPRIREEDDDEDNPIAATSISSIGSDRKTGIGIGFSKAGATSSTITASSFTSSKGGIGSRTSIAHTPSSDSPSAFTSQTRSASFVRDSTPTVRPAAPLSYAEQAHFAKLSGSFGARMLGKMGWKAGQGLGATGEGIVTPIESKMRPEKSGIAFRGFKEKTEQSKMEARRRGEVVSDDEDPKIRKSRKKEREVKEKKAEAWRKPRKVKTKFQHKTYEEILAEAGTESSTSAGIGQIIDATGAVPREVSSLADVSINSWTPTMDSTRIPEVRHNVRLIAESCKTDLDGLAREGKLLEERKKLVVQEDLRLRKRIEDEAELIARLQQIHIVTNEIDAKAKELSADYDASLDQFSPLFYRLTSEFEPELDRYRLDEVVVGAITPLVRRIVAQWQPMEDPRVFISTFRNWRRALRFNVEDETLPETQVDIYGTTTVVSSPVQIQKPMTPFESLLWNVWLPKVRTSLNNEWSAHDPQPALRLYEAWSTFLPPFIRDNVLDQLILPKVQKAVADWNSKQLDKKVSLQTIVFPWLPHVGLRLEDFVGDARRKVKSLLRHWAVGDDLPEDLKAWKDIFDANDWDSMLLKYIVPKLGATLRSDLRINPRNQSMEPIHYVLQWSSILRPSILSQLFETEFFPKWIEVLHLWLIQPKVSFEEVAQWYSFWKGSFPENIQSVSGISRGFTRGLQLMNQAIELGPDAPSQLPKPDYRAEQAQHALTNSPYSRLSNNGGRAKTNASSSFRPSARTQEITFRSIVEEYTASHDLLFMPTGRAHEKSRMPLFRITPSMDGKGGLLVYILDDAVWAALEGAGGPAEEYRAISLDEVVLRAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB39</accession>
    <name>A0ABQ8VB39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_921658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="46752" checksum="165B4619D3DA42BF" modified="2025-10-08" version="1">MTAPYASTSAGVSDALGIPPSSPNRRDSDVDEIVSNVEEPSLGQLSLFKSVFGVGVSLARYIIDDPLWSILAAAAIAMIKSYVSLDDYALATWLSLVVSWRSTETRSTNSTSALLELNPLDDQDQRELDCQELREFCQHQPLVPGPSTLVPHTSPLAGGSSLLPPAPVMKKRKRLVKVDPGSTPKRRRLEQVVDRSSPIVPTVPQVEGGSSYRRVVLVLRPPHVPDSEIPTLPGVGHLVPEDSSHRSVVDQSRSQGYTKIPPCVPQAGLFEQFVPPSEVEDFSWSRIKTPPCSREPLRPYPRSQASSALRVDNDHLKTEVEELRTLLAQSRGQELEASRRSLEEVARDHAEYQRVLSQFRAIEAELPEPASEDLVTRFLIAHSEVAKRQKQEIGELRKQVDDASSHSSDAYAELDSANARALRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB49</accession>
    <name>A0ABQ8VB49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Syntaxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_921864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06897">
        <property type="entry name" value="PX_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="2">
        <location>
            <begin position="300"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4484065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="363" mass="40362" checksum="AE619489972E7C16" modified="2025-10-08" version="1">MTAIQSVHISGHQERLEPKTHTVYQIDIRGNVRSWSIWRRYSEFDDLHVELVKGTGSPPPVPLPPKHKYSILRSHNNPALLEERKTGLEAYLRAIIGAKEDKWREAFVFKEFLGIPVGRQGGVVGGPPTQFTLTSWLDEHQELQNRLRDVRADINKREALSNQGDVSASHKSNVSAKQKLAGVLSRIGTLGKGLHDLAMNGMSEGELQRRTDMVARLQDDCEKLGKMVTVARQFNRAGTDPTAPYSPASMNPASASDREALLGPTNTFTRVTRVFGQPSKPQETEVTRPLDDLGLFGLQKTQMQQQDDQLSQLTTILSRQKQLGHAINSEINEQIAVLDGLANDVDNVGDKLSKASRQMHRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCW3</accession>
    <name>A0ABQ8VCW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Vesicle transport v-snare protein vti1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_770347</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="41"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="160"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4482653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="225" mass="25589" checksum="6912BD6F38D01DD4" modified="2025-10-08" version="1">MDTSPTALFDSYEQDFKQFIETIREKLEGDENQDEQRKASLRRVEMELDEADEMVSQMDIEIQGIPQSIRPQYQNRLRSAKADLSRFKKTFKDLSAQLARSSLLASSTPRPGYSSDDPYGSSSDRSRLLAGTALLEDGTKRLQDSQRLALETEDLGADILSNLRVQREQIENSRSTLEMANNSIARASNKLTSMIRRMYQQRFVTGAIIAILIFLIIIVVWSKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD52</accession>
    <name>A0ABQ8VD52_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_867868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="46618" checksum="506D74CA0420B56B" modified="2025-10-08" version="1">MNFPQSQTDIGYTYTLGTLILVAGVPPQQFADYLVGFNTQVNSVFTLLTGSFPTEINPTTLIILLGPALNLISSSLLSNLSQLLPCFTSLINIDIRIHDSVWSRRLVDKLPIFPQSVKKAKVLVSNLLPNGPELVRVVYNANASPFTTSFAAVFYEMHLSMKGHQALDLSFMFALHGALTAIDLQENCIVEIEIHGRSIFLRMSGRLRDVCKVVECAMDTVATPKFASRLYTVKSLVVDVPMLHYRDDFEHFVHAVLSKAPRLQILEVNFRTVNSIETHAWMGSVRMLASLRELIRIVIAHPRPLILTDADVAHLLGSWRKVEHVSLNPKASGALITRSQVLLTINALRIAAFQAPTSLRHLSLFLNADEDSVYGFRGLQPRYGVEKIELRLATSSAHRARVAIRVAETLFPNADIKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDH8</accession>
    <name>A0ABQ8VDH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_836104</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045199684" evidence="3">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4489140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="204" mass="19760" checksum="4932E6C621DFEEB1" modified="2025-10-08" version="1">MMLSKLQLVLVLSTISAAFAQDTTSVSSSGVSESSTTGTQVTDSTSLITSTSAETSLTSTLSSSTDSGASTSITSLTTTTTSSSSSLLSESSTSQSESTSTSTTTLSSVSSSATSTSTDTTESTSTATFFVTSTLPPSSATSSTSSSSSGLVVTITSSDVVPSTSASATASTLGTNNAIAAYGGSIPSVLVLIGGALFGAALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDN6</accession>
    <name>A0ABQ8VDN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_392758</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="301"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="306"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="406" mass="44025" checksum="4C80EF779C23E30F" modified="2025-10-08" version="1">MYSSNRQRRILIAFWIYSQSSARKETTTTKKKAAAKAKNQSNGVWPCEMNGCNKQFAREADLKRHQRTTKLHSIAGFACPQCEANFTRTDALRRHQKSRHNDSVCDPMETEDSGEHPPNGSAVISTSKENGRDAVVPETIQGTPSATGPATGHSSYYRESTTTGSYASPPRTVFGTEYEHALVFIRDNTEFLFQDGLMEILHIPSVKQPTCTSSSPSTSSSHSHQNDAEEPASPFLLSYKSASILAPIPPLPPPVQLLEPLLVDADATQVTRSSSSEPPCSQEGYSHNPLMKHARTWSMSDEADMSGGESSLFSSTSTSSSSSSVASSGSPSTSKGSHIMREHGYGSRLIRPEPLEPIMTENGEPMLDPAELLTQVGWVALYDGSDSLSDDVRPTSSHESLSPAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE33</accession>
    <name>A0ABQ8VE33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme/RWD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_884938</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="23"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4485171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="183" mass="20723" checksum="6488F99C993B5DFE" modified="2025-10-08" version="1">MIKIWSMKKNEEAAGRKKPKTSAAQIRVQKDLTELDLPSTMKTHFPDPADLLNFTLTIVPDEGMYKGGAFNFSFAINSNYPHDPPKVKCTQTIYHPNVDLEGNVCLNILREDWKPVLNLNAVMVGLQYLFLEPNTDDPLNKGIIFIEAAQEMSKNRDQFLSHVRSSMRGVNIKGVQYTNVIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFX6</accession>
    <name>A0ABQ8VFX6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS polyamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_837444</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF134">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="102"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="547" mass="61151" checksum="DDEA18BC5214E2CC" modified="2025-10-08" version="1">MKNDQRNKTTVASLSPGASTIFVEPEVEDVIVKSAEGVRESNIDPMLLSSSKRPNSKEYNVKEGVAEIEVESTEQHDPLYIEFEQGDLRNPINFSSSKKWAITALACFSTLLASSNASTYNLGFDSMMVDLNCTEFQATVGLSLYALGFGIVPLVTASFSEEVGRQPLYYISATGVLLMYIAIALAHNIQTVLIARFIQGAFGSTWATMVGGTIADIWQSHERGLPMSFFAVAAVGGTGFGPIYAGWVEMNPRLQWRWIQWIQMIITGFYLVLVPLIMKETRSSIILMRIAKRMRKETGNPRYRARIEDEGVKLSTLIWVSCTRPIHLLTTEPVVASFSIWIGFVWGVFYCLIESVGSVFRTVHGFSTGQVGTIFVTFVIGSLLGFSTNFFQEHLYRENYRTRGPEARLYLTCCAAILVPCGMFIYAWSTFTHVPWIALTIGMTVFLYGTFIIYLAVFTYLADCYGPFASSALAGQSLCRNLAATVFPLFTQQMYAKLSYKWANTLFGCIACVLMPIPFILFFNGPRIRSRSKFSRAVMQSLQLERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGM1</accession>
    <name>A0ABQ8VGM1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_764528</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052247">
        <property type="entry name" value="Meiotic_Crossover_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835:SF3">
        <property type="entry name" value="HELICASE FOR MEIOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47835">
        <property type="entry name" value="HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="94"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="300"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="973"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1025"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1076"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1240"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="975"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1240"/>
            <end position="1250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4493398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1285" mass="145078" checksum="5A75658B22BC08BC" modified="2025-10-08" version="1">MQYHTPGPSHCENTMIYDPEQVVQSQGYQPRNTQKLSLRPVSNLPDMYRGLFKFGVFNAVQSSCFDGVFHTKENMVKAPSPCAHSLLIFLQFLAPTGSGKTVLFELAIIKMLSEARETGQSVKSIYVAPTKALCSERYRDWANKFEPLGIKCCELTGDTIHFGKSAWGDAKNATIIITTGEKWDSLTRNWDDHHHQLSQIQLFLVDEVHILNETRGSTLEVVVSRMKLRGTAVRFVLVSATVPNIKDIASWIGKDAQHGSAQVYEFGEDYRPCKLIRHVVSFPRSKGQSDFVFSKNLDYKLFQTLQTYSVGKPILIFVSTRKGKTGVFSTAEQLCKDHNEAAAKKQSLPWSRPGRVDRIFYDKRLSEFASLGIGVHHAGLTPNDRRTIEELFLSKILRIVIATTTLAVGVNLPAHTVIIKGVHTFQNSSSVEYSDLDVMQMLGRAGRPQFDKDGIAVIMCESELENKYRALVQGKTIVESSLHLNLSEHLNSEIGLGTITNVNSAKEWLKSSFLFQRIQKNPNHYSLGKDENQTWEERVDDIVMQSVESLRNSELVSREDGSDAIICTEYGDIMSKFYLRQRTMGLILDLSERASMREVIYNKLRRHNDMRYEVKKVERTSDKILLLIQAILGGISLNAPEYRSNDSQPQFEAYSVFKHLPRIARAIVEVAIVRRFGAPLKYGLELVRCSTAKAWEDRPVVLRQIESIGEKSLKASGQTSSARQVLAEHGITSIPILRKQDTLRLETLLNRRPPFGLEMLASAQEFPVYTLRVEEIRVHSDGGRTPVDIELSVECGLLQEVGPSKSKKQKPSRFSHMTSVLTLTSDNQFVDFRRIPTKALKEAKTFEICATLEKPSQTVIVSVSSESYAGVTVAKIHKPNLPSSEYPTLNTKPMTALRPSFQRRSSYTEKTSQWTIRVCLSMNRCAFGAHHADRCNHPCKDKQACRHLCCREGLRVPPKSKTGAVAKTTVKPNVVNDTQNQTKSKGFLSNLKPTPSKPKPKPRVKTDQTLDDLDKLHKSTNVQQNLKLSQGHRIKLDPSPSAPSIKRKNRPVPNFDIEFASIATVDTDILDLPASLDDDDDLPAPHEILASSNNKKRNYSSEDNYSNSELDALIRDIPSDDIVRDAPKSLTKVVAENKEPAKKKFKLDTLPEHKVLSSGRKPLFLADNEGSVLDDDQEIEFVEEPTPGHDYDDFMLDSQYYNDIPATPDLTTSMRSFEDEEDELDTELMSHNNFVQEIERTTNFPESLQPKQQGQNEELNEEEKLQQEYEDEFAILEAWIDEHME</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHS2</accession>
    <name>A0ABQ8VHS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_980740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="306" mass="34892" checksum="D6A6BBCB51FA1C69" modified="2025-10-08" version="1">MSSFPIHSDESLTSVDAALALFHENKDIFIELGAREHFNIPKIHFLCHYVRAFKLFGTSDNYNTETTERLHIDFAKDAYCASNRKDEYSQMTKWLERREKVYHYASYIAWQQSQPQLDVPSPTAISGVRYDFPGSQKTLHDMQCPLTQNFANFPTAKTVSISKLEERSLLGYGATQFEYALKRFISQFCNPEFTPAQVDEMASFLSLPFRGVPVWHRMKFRNEDLYGKKTLDVVSAHPRRLNAQGQVSQTSQFDAALIRVQKDDDNGKFLQGCQIGACPGYFLPPKPTLEPTVSRKCDSACPPCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI89</accession>
    <name>A0ABQ8VI89_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxin-14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18256" checksum="8D35BEE15724C911" modified="2025-10-08" version="1">MGNLLWFFIGAGAATVYTRRRDHLQQHEDFQSGGSSHRCHSHSPQTHSSQEVAQASSPDTEPFFRNAPSINNSAPTPSLSQDASGSSSTTSSSDPWAVEKERMREIGNQVGVNVLEFSESTLDTLLSSIASMKARVVQQRLDREKHEEKKNVVEEQKQDPLRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ76</accession>
    <name>A0ABQ8VJ76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_715992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="120" mass="13361" checksum="455F1F60509A12D5" modified="2025-10-08" version="1" fragment="single">TGAFRPERVKEILRKVKIGAELSADQRARVEQLLSSYADCFALSVGEVRPVKNAVHRLNVPENATLPKKVRQNQNLGVSPPQREYLHAKIDKLLEAGVIERCNPEDVKCVSPLTLAQKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJH6</accession>
    <name>A0ABQ8VJH6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="169" mass="19796" checksum="31B8593A65A590D3" modified="2025-10-08" version="1">MALKARFLPCLRMSERRWREEEENTRREEQRKRDAEEQKRQEEEGEKQKKEEEERRLQEEKEVVIQEAKEREERVKSEEENRKAAGMTTSEEDWKEVVKTQGTRLVKATPTLKPTWSSARHAITAKIGQLTNAETINRVTTPSSSIYRPLAKALVLQAETEIEAVCCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJM2</accession>
    <name>A0ABQ8VJM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_833652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="372" mass="40237" checksum="076A7FC9ABAC6439" modified="2025-10-08" version="1">MVAIHDPTAFGTTSLSPQLSPSPTSSSHSKISLHSFNIRSLIILSAAGLGIVIAFAAFAFIFYKRFYSSSVAGRANPVSQVKSDGGANYSKLKPLKLLCAKNQFASEEKTAIHTNTNTIAHAKRSSLVQGISEILLAQDNTHSLPSRPPGPLRLNRSYRRQLNAKKPPSMHTTRPVVSPALNPSLPLPACTFNEIPVLCSPPSTSPKEIFEWIQSDSVLNSHDGYIRAREDSRIRVFPSLSESGTPTSILTQQAHISSILSSSTMNRTYGVREQSLSRSLRSPLCEDPSPTNPNPRGQTSSKSEGAAHVPSIEHLFKEGCYLGPLEQGTRWGSISYTLDKPISKRKDTKTFQKSSKAGKAGKENKGSISLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJV2</accession>
    <name>A0ABQ8VJV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]</fullName>
            <ecNumber evidence="3">1.3.1.124</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_825899</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:45912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85101"/>
            <dbReference type="ChEBI" id="CHEBI:85493"/>
            <dbReference type="EC" id="1.3.1.124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:61892"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85099"/>
            <dbReference type="ChEBI" id="CHEBI:85493"/>
            <dbReference type="EC" id="1.3.1.124"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.124" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05369">
        <property type="entry name" value="TER_DECR_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045017">
        <property type="entry name" value="DECR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43296">
        <property type="entry name" value="PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43296:SF2">
        <property type="entry name" value="PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4496546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="30771" checksum="6580CAD755BDE128" modified="2025-10-08" version="1">MAPTSYIAPLGDSTSVFKGDIFKGKVLFCTGGGSGICRGMTEAVMRHGADAVIVGRKLDRLTQAAKELSEATGRTCIPAQADVRQPNMLKDAVKKTIEKFGKIDFVICGAAGNFLAPISGLSENAFKTVMEIDTLGTFNTIKATIAHIRQSKGSYIHVSATLHYKATPYQVHVSSAKAAVDALSAVLAVEEGPHGVRSNVIAPGPIGNTEGMQRLSSLADGIGSLFPLGRVGEIKDVANATVFLFSEAASYITGQIVVVDGAMEHMRQFQFPYPQAVLDPGSVRDMIQGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKH8</accession>
    <name>A0ABQ8VKH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="38284" checksum="7560AEBF23E87760" modified="2025-10-08" version="1">MDQPVPVQPSPFADRGLIGSFPPPYQSQAPSQNPPQPSRSPQFWDSGIMVVFSAVQELPPQQTILYRVSIDSLRCRSKVLDDIFGIPPSTQSQNEGTEGNPIALPTSITSEKFESFLMYLNCRGWNEFDDKVPANILNLLDISALLEADGALSYAMSKVVGLRLPAAQLLGLAWRHRAHPQVREWIEPAVMGLLNTPLRCHSADQESSIGLAYPIIAKARERIQEARLILAAIPFQLAPRDLLFPECPDELHEYCEKSWLFFWYQNITVELIHPTKPPLSYNGLVQLVQETKFENLQDGCKARTLDRMRLYGDYPTVPDIFHSAVLQIIELFNIPSSKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKT1</accession>
    <name>A0ABQ8VKT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tetraspanin Tsp2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_760579</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="39794" checksum="2066EB2F6C06E0F2" modified="2025-10-08" version="1">MRTDSKSTLSRTGSHSTSSRASVDSGHKKLIPSIQTTEKFTSKWPRPQSLKALNINRSAKGWRNRKGVIQDTILELEEGYSLGLDKIDRWTRFKWCLMVSVITVLCYGSGAMICAILTWFRTWNHADVMYVADNDILILITLAGSILMFTALLGLTGTLLNSRPILATYTLLLWPALISMLAVGYTSYKRYAFSLDRKLNFSWSQYYTPLGRLMIQSSLRCCGFYDPLHEATMSNKCYTRTPLPGCKAKLFRFERENLSLIWSTTLSIISLHLINIFVALLCSNHVTSVFGKGITPKRYRLSELDLKADAEKIRSQIERIRPTYSRASSSMVFREDREERTSLLRDSPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKY7</accession>
    <name>A0ABQ8VKY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_792314</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="532"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="919"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="128"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="288"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="789"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="796"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="810"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1099" mass="122680" checksum="AA5F34E0FDBD6128" modified="2025-10-08" version="1">MSTTDQAAKRADILDRIRLQRQQGKILGSPLTSLSSSSSYSAPPAQSRDATISSRYFPQTPGSPNDTVLVPSSSPLNSPVNRNPNQSYTQPRWPDVAFRNGAALTGSWNLSQVAPSYDPLSVSSGFTSQNTFQRGSNVRPFSPGDSESGPPGIQRPGQRRRTLLDAGSTSSEESTPESSSRTRLVRGRPADSAEPPLPSPPADIFLDPKFVRFNMTMPGVPSHRVRAAWLHAKQDVRLATQLASDDSWVPKSSTPLQSSPSHSLKASTGIHGKVDGLEEAHKAKLAAMKEKSKKSSIYANRPNAPKVAPPATPSVKNPPIDLTAESPAISQPVRRKRNKNMIVDSDSDVEMDDGEEERSHKRSRQESHHELRVLTFFNTQGAEALQELTGCTQVQAQAIIDLREFESVDDLNTKLGQGKKKAGPAGLSPRLIDEAVEIFKGYTAVDEILEGCEEIGAKLQSSIATWTTIPFKGKGKQVDALSESVEDGALNLRTIPSLKEHRPKGYISEQPASLSDSVKLKDYQLLGLNWLHLLYRSNFSCILADEMGLGKTVQVISFLALLRERGNKGPHLIVVPSSTLENWCREFARFASSVSVQVYYGGKNERVELRQTLLDTRRSMSGSEDDGWDVLITTYNLAQGDSDRKFFRRIEWDCCVFDEGHVLKNFQSQRYSSLLRVQSRWRLLLTGTPLQNNLQELVSLMNFILPNQFGDALDDLRQIFKVKGDSKASLLARERVSRAKKMMTPFVLRRRKDQVLQDLPKKTERIEWCEITPLQKSIYHDTLQRSRKTVLESETPVDSATTSDTNGRGKAPRKTRPTAKAKEKQYLENSANVLMDLRKAALHPMLFRSRFTDDILSSITKQLLKEPDFKKRGALFDIVKEDMSVMTDAELQHFCGLYKSTRKFGQPSDCFLDSGKIQMLLSLLAEYQKEDRKILIFSQFTQVLDILEVILKERDIRYLVLTGSTPVDVRQSLVDEFTEDASISIFLLSTKAGGMGINLTAASVVIMFDQDFNPHNDRQAQDRAYRIGQKRDVEVVKLISRGTIEEDMLKLSEMKLALDEAVAGDDEKGESAPEQEMKASLMSTLRRQFEKQEVSAVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLH3</accession>
    <name>A0ABQ8VLH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_823384</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF83">
        <property type="entry name" value="SYNTAXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="229"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4497131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="357" mass="39710" checksum="D5FFC533B3038FCA" modified="2025-10-08" version="1">MNVTTRSRTGLFLSYRDSRAPSSKFSRKISTYDEPDTALADEHEGLIANTHHAVDLDLPPKWVDISEQVQLILTDTQAKIAALEKLHAKHVLPGFADRSLEEQEIEAATTDITKEFRRCQSLIQRISAPSSHSFPPSHSDANKSKSEIQAAKNVQRGLAAKVQDLSATFRKKQRVYMEKLQGHAIKNQDLLLASGTISLKGSAGMSAVDEDVEAATHTQSLSFRQANPAVDVQTRDRELSEIAKSIASLAELFKDLSVLVIDQGTLLDSVEYNIEQTAIQVKDAVQELDIATRYQKNTGRRKCIFLLFLMIFGLVIVIIYKPKHHSSPPEPLTSTPVVALHFNPRLFRRGFFISPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLL6</accession>
    <name>A0ABQ8VLL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_822766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="22380" checksum="DA247241FC8D799F" modified="2025-10-08" version="1">MPQTPISRTYKAGGSSIQATPNTPTLDQKHLKYPSLTSRYTIAPKSARKSTPMSDLIRRVNSMPNSQFKSPIPKGGNRSGGGNNTPTTFNGAVGSLTAYSPYLKSSRSFLSRIAPLHPNRRTPPPLPPAPPPRKKTRKEIEWEKKDKEEREEMEERWEEELVERVGGMGEWLGMTEDMRKMMKRAKRDRELGLGGWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLS3</accession>
    <name>A0ABQ8VLS3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_918815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="43579" checksum="06025CB0146EBDCF" modified="2025-10-08" version="1">MPPLSDVWLLLDNSQMASSFPIGNWVTSLSGGAWLGSTAITIGSPGGNILVPFQGTSISFAGNTPSSSDSPTWFLVGIDLNSPYNVSFPNPGILQSYTQWYQTPTLPDGLHTVNLSSIVVNLDYAIITAGPTTPLSGSTIVVDDESPEIVYNGNGWKTSDSGIDIGGSWVNGPPLGNTTHSTSNMGDGFSFQFAGSNISVYGVFEWTATGSVGVDFTLDGITTSSSLSVPVGTAISHPEIPNYLHFSSGTLKAGNHNLVMSITQSDGNQSFVLDYLTYEPSFSSLVEKPNFTSPASPVSSGSESSPSASNTGVPVAVTHKRNVKAILGGAIGGVLGVVLIFVVLRFFLLHRRIQKTNRERRVEGIIIHPSVTIYKRPRKSTEIHTSRIAQSATKSHSDPGLEAPPPSYDELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMV9</accession>
    <name>A0ABQ8VMV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_980234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="170" mass="19288" checksum="35D2B41D8E3DB0C4" modified="2025-10-08" version="1">MRSTIASNLADALFQTFQQFETLQNDFQKAQNEWLHEAGVGVLSILRHVEAIERDLSGKLKQFDGVLVSFSAQSETEINNIDNVVEARRTRSTNVSLSAGIQMEILRLVEMKVLLPEKMWHTETGILEKLDKFLIRSHHNPDINDYVALQQASLEILGRVLECILSNNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMY9</accession>
    <name>A0ABQ8VMY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lactam utilization protein lamb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_820968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003814">
        <property type="entry name" value="PRK05406.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003816">
        <property type="entry name" value="PRK05406.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292:SF0">
        <property type="entry name" value="5-OXOPROLINASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBGL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="29293" checksum="3BE452D85A50DD39" modified="2025-10-08" version="1">MKTQELSSMSPLKATVNCDMGEGFSLYTISDDEALMKTIHLANVACGFHASDFSVMDKTVQLAKEHSVLVGAHPSLPDRQGFGRREMKMKPEELISCFVYQVGALCGFLQKYGLVLNHIKPHGAIYGQTARSDELAHAAVSVCKIFSTEDHQVAFVGLAGTAHQTAAEDLGVRFIPEWFADLDYSQSGELIITQIHAPVKHDTICDRVERLLKYHEVSTNANTVIPLGRNVNEVTICCHSDTPGAVENARLVKSLVDESNRLAGYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNC4</accession>
    <name>A0ABQ8VNC4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_186381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14303" checksum="4868AD1E69FAE2E5" modified="2025-10-08" version="1">MNPLIGLLTIFFHASLIILTHKRPELKGMLSVEAVVFAYLLSLSWLACFVVMVYVAWKSQGRSSQLLGMDEAFLTAIDNATQRLQLMCTSLEFGLLGDLAVRSTWARRSEFEDCAGMDYDHYNVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNV7</accession>
    <name>A0ABQ8VNV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_916721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF26">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="142"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="415" mass="45626" checksum="9EB278D68AEBDD9A" modified="2025-10-08" version="1">MAISLRHQPYKALYTAFEFVGTVLVKVPFWLLLSIPRSWRPRPSWSMKDSFLIQLLRNLVSVRAKTMSKAASGYPTRQLGALGEGVYCVWVTPIPKLVVGDLAVWSRTASVSSIHVQGYWYCKSVNATIPKRALPGEKVLYSLHGGAYTYDTAHPSGVNAKVIQRLLNLDCSINCAFAIDYRLSSGSSNPFPAALVDALAGYYHLVHTIGFNPSNIIIEGSAAGGNLALALTRYLIDYYGHSEAVDLPDVPGSLILLSPWADIGLAPVKARLESATINNTKSWLVSDYMFGPQCPMTSYSQHVFLGPHGTDVAAINEYISPSSRHPLLDLDFEDFPRTFISAGAAENLLPQIRLLRDRMVRDLGHDDKGSEKRGKVTYHEAPDASHHCLALPFAIQKDAQRELLAAISEWLVGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNW7</accession>
    <name>A0ABQ8VNW7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serum paraoxonase/arylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_757658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051288">
        <property type="entry name" value="Serum_paraoxonase/arylesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799">
        <property type="entry name" value="PARAOXONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799:SF12">
        <property type="entry name" value="PARAOXONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="410" mass="44555" checksum="6404A1FAD20F856D" modified="2025-10-08" version="1">MPSSVTTVLCAVFASLAVLYQIYVSLLVKVVGLFRTVQTFGLDAAACKDIPELQACEKIVLHQPSGLLYLACSTPESRLAWTPAMDQLNVQGRSNDDYVATYDPTTSKVTRLQLENFDSDQPISVHGMDVVQSTSNGNELFVFVINHRAPPTGQDSRKVGADSVIEVFKTTVSGDRLVHINTVRDPRVIVSPNDVVGEADGKGFFFTNDQGSKISNSYNLFSATTSVGYCHLDHGCKFVALGLYSSNGIVKASTNNTIYVSSNLGGKINVFERQSDNALLLKDVNEKGQALDNISLDNRDQLWVAAFPKIRDNIENLSKDPHHVASVAAFKISANTGGSSHGEKYNVEKRPLLLSCHTCFDIQILEDDGTIVSGSTSIVHDSDRGLIFMHGIAAPHLTVCRMLALNQSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP03</accession>
    <name>A0ABQ8VP03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_759117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF5">
        <property type="entry name" value="ISOCHORISMATASE FAMILY PROTEIN FAMILY (AFU_ORTHOLOGUE AFUA_3G14500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="99"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="288" mass="32568" checksum="48A0D23D7A9262EC" modified="2025-10-08" version="1">MDSKGHTKLGAGDSYMVFDILDEELSEIAFQKVKEEVKFDIMHHKGGQVPRLVAVQGEVAKDLSFPVYRHPSDESPPLRNFTPTVELIREKVQKIVKHPLNHALIQYYRSGQDYISEHSDKTIDVVLGSNIVNVSLGAQRTITLRTKKDQVRTDEGSDGKRLSQRLPLPHGSMFVMGLETNRRWLHAINHDNRPRKTKSPEELQQNGERISLTFRHIGTFLDGPNERFIYGQGATGKMREEARPVVNGGGPEAEALLEAFGHENKDSNFVWDEWYGNGSDVLHFTGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP54</accession>
    <name>A0ABQ8VP54_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_758056</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF25">
        <property type="entry name" value="MAP KINASE KINASE PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="39"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4498142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="40126" checksum="C79B94DE4ECA85C8" modified="2025-10-08" version="1">MISYRDPNGRLNFKGKAVLHANGVNFANGVSFRLNMEDLERGEELGRGNYGTVTKVLHTPTGVTMALKEIRLELDNAKLNAIIMELDILHRAASSSHIVDFYGAFFVETCVYYCMEYMDCGSLDTLVNFSFGETGVPEDVLARIAGSTVKGLKFLKDELGVIHRDVKPTNVLINNRGQIKLCDFGVSGQLEKSIAKTNIGCQTYMAPERISGEHQNTVGTYTVSSDVWSLGLSIIEIAIGRYPYPPEAYSNILAQLKTIIQDDAPTLPTDRYSPEACDWVASCLVKVPDGRATYAELLEHEFIQRDEAKANAENGDAVDMAGWLSKALQFREAKIAHVQALAAAALAPSAPPGHPVLSAPATTRIGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP56</accession>
    <name>A0ABQ8VP56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_819574</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="872" mass="97205" checksum="B59B28BDCF3F05CF" modified="2025-10-08" version="1">MSFPATTEAIDSLEEYEDIIAWINDTLTASSSEQDLESLMNLDQQITQLIASLDIACEDTSSQLERTIDDVSRGIPRLTYDLHFIQDNALSLQTSLATVHSSSRAAIPDTTASALEQLKRLDTIKGHMEAAREVLREAESWSTLELEVTSMLTEHNYAKAASRLSEANKSMVVFQNTPDYDPRRMLLVNLQNQLEASLSSALVAAINEQNLETCRNYFNIFNNIQREVEFRNYYYGSRRAPLAATWHDAELLDAAPQGKIVSGQTFSEFLSKFYASMLALLNQECGSIPAIFPDPAHTLSAFISSILSSLQPTFSQRLSSLSSYYADSALKELITVYRVTEEFAVGVVKLMQKIQYSAVPPVKTSSSDPATPTHPSHSRKRSMRMSISFRSGTNMTNSGSQKISSLVDGLDWDQELFHPFLEFQVDYGSLERRFLDHALRDILSNDTRQKASGSDQARIFRERAVDIFSIAEESLARCSAFTHGYGSVSLLQALDGFLKSFVDMWTADVSFAFPGPHSTLQEAGSEDLSGLDYTSQDWQNIQTMLHLLGSARSVYERMNSFEVKLRANLANTASKFRLHRGDPTSFPIADTKGAEQIFEQSSLNSADLHALLDKIDVDPSHIRDNFSRQQGTASSTLGEPLLTDARSAMFEFAKTCQISLQDTILSPLRQQLASYALSSIWVITTEESRNTTFNDLQVPTFSLSPSEIFQRVTEGLLNLPRLFEVYADDDALSFSLQTLPYADPELLKNLPAASLPDIPSHSRRHSVTKPVTLDPEMVSTAWLSSLGQSLLAHLTTEVLPRINKLTSAGAAQLASDLGYLSNVIRVINVESEELEQWKEYVELNDDAGKAKVDTKNDEDRVLNHVARMRGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP96</accession>
    <name>A0ABQ8VP96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_165112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="151" mass="16258" checksum="642B89990D471F77" modified="2025-10-08" version="1">MLVPNSATLVQALDSVSSSAAASSNSKPKTPIIAGSVCGGVLGLAWIIGFAIYFRKRYKRKLRNQGKLPPLEAKKLKEESQEKIVIPPDPAVLVGHRSGEHYPRPKSAKAPPATFLSPDKSHNEPSNKLFNESPNHHTSAGPANSISRNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPH7</accession>
    <name>A0ABQ8VPH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_821171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="52448" checksum="249A0F9042808F08" modified="2025-10-08" version="1">MFFDHLGVRPPSPEIHFCHWGFACTRSFCSREDILQHITEEHVPTAVPVYRHELPMLHRMTEGIGESYETEHFLSSVLRSAKGEGGSQGDKNSSQDSGPAASLPSPPVSLSSRPGGRADDEYSILSGSESPRSQAQEPSPMFYEDLDHRDFMAQSTNILLSDALEPPSPGFASLDASTGSPRPGSIPPSPSFSDILASSTQKGLAKPHSPIPSRFLAHTLSCDSSSSSNSCAIVEEQLTPDDDFSFDEDRDGLSQNLPVAAEESDYSDLSQGVHELGASQMFFTQQPTESESQISSQTRRPFLHVRGVQNTTLSSSTSSQLPPPEVAGPTRKQSWYGPTTRPRKRSRGSNLSPSVSPVNTPAASPHGVTAFAVSSSASRSRRTRGIPDQATPHRIRDDRSHSGLHRKRYNLNSTDPDDANSRLPQIGYNMTAQHSSHDADCDADVSQMQPETQLTMSPAIQEPSYGMYDYAIQTQAPYDSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ46</accession>
    <name>A0ABQ8VQ46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_702032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018482">
        <property type="entry name" value="Znf-C4H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31058">
        <property type="entry name" value="ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31058:SF2">
        <property type="entry name" value="ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="17758" checksum="5B0668AEE96629DC" modified="2025-10-08" version="1" fragment="single">STGAGTGSTAPLVATGDWTRDLVHLAKTAELKKHALTLQLHTAHILSAHAALEQKSKSIQDVKEQRNKLESERTRLLTALRQVNEDRDKADLLEGDLERESTTLRHQILALSDGEYAVAKADVDRLRAELGQPALPSLQTMLDEKASTYLTERRLNGNGNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQA3</accession>
    <name>A0ABQ8VQA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_916491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="150" mass="17375" checksum="D5BF0C658B3820C1" modified="2025-10-08" version="1">MPHGDHEQLPETSQTHLINLHLDTDSTSTKPSLDPNPTLYSHLRSYPEQCLQHPYRSGLENPSSATLSNRDEFPVVDDLNQLHREPYYSYLWHHPNVHFSKAYRNRQTPVFIRTEPRPQRVMSGYIDPLSLSKNPAKRSLDHIHQCNVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQB6</accession>
    <name>A0ABQ8VQB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GIY-YIG nuclease family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_864484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="24589" checksum="CF1C524E2B78612A" modified="2025-10-08" version="1">MAKRGSRKLHTLYISRRSRVPSIADGPGFLYAFVDHGVFWKVGMSIDYDRRKAEWERQCPCPSRVWLPPMRVLRRRKSESLAHLLLELACFDRPRIHCFNCSKAHIEIFLIPGHCVILKDKPAKMNDIRDTFPFGYLGHRDVLMSQRPDIDDVLMSPRPDIETSQCPDVPISTTSRCPDVPTSRTPILGEIILKNLMLSTRRIFRENFNLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQU5</accession>
    <name>A0ABQ8VQU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_900985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="338"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="37"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="478" mass="49726" checksum="6CD4499830DBBE45" modified="2025-10-08" version="1">MDISSILDTGSSSSSLSTSDTSAAAVSPTSFSSVTGTTSIVIPSTTLSPTSSTPAVSSTTPSTSIFTTSSSSPSSSDSSSTSSPIISPTTSSITLTSTVLPTSSTSSTPVFTTSIQITTVSNSGTQTITITNSITPASSASSSTTSLASDSSSSSSFWSNKGAVAGTFIVVTLVGVAIIIWVIVLSVRRRRAHKFDQENEAAAAEAANATAPAFLDDDDDPIYRRDYLHAGDMSSGGYSGYEGGGPIYTGAVPSASSHGTFNQPPMGIQPNENYPMAEFGSVLYPGASPYPITMAPGQNPQHNNYYDHGFVGNEPLSASTMKTVRPTSGDFDVLEQQQQRNEGGSDATNYTSTGTPHTTPSVSRGHSTTTSTSHSRTDLFRNKSQGSRSLIDGYYSKAPSTTGGHDMVSPHSGESYAAHYQPGFSGMPKSSPSRRSTFGYDEAPPLPNLFSKTIDDEAVDDSDDEGFQQKKVLKVANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRD2</accession>
    <name>A0ABQ8VRD2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_107927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_bL21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_bL21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="153" mass="17302" checksum="B7FC2B49B520DA91" modified="2025-10-08" version="1">MASLFKQPQSLCRSFCRSIHAAPYTTASALDLIRSQPSQYVVATVVGRKYVLAPRDVLTIPRLRDVKVGDVLALDEIHELGSREYTLRGNPTISPSKVKVEATVVEHTKGAMEFIFKKKRRKGYQKTKKHKQTYTRLRIGDIEIPLPSIQPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS39</accession>
    <name>A0ABQ8VS39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_756303</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047053175" evidence="15">
        <location>
            <begin position="19"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4498776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="535" mass="61254" checksum="4AD49CFB89DDC151" modified="2025-10-08" version="1">MFLASASLLLLSIWLIRRLYIIGRREPSLPPGPPTIPLLGNLNIFPTEYAHYKFTDWAKEYGDIYSLKIGPGTVVVITSMEAVRELMEKRSGNTVDRPPNYIADNITGGLNMVLARYGSKWRILRKTAHAILTPNAVTAHLPIQIAESTQVMYDLLKTPELFYTHIRRYSNSVVMSLLYGKRSPRYETREATLFFESQHLWELALEPGAHPPVDVFPFLRYVPRRWAPWKVLCDKTREAQRKLYFGLLDECLKRVQRGKENGCYMEEVIKRQDEFGLDRELSGYFGGVMIEAGSDTTSSFLQSLILLLTAFPNVQRKAHKEIDQVVGDQRVPNLDDVPHLPYIQAVIKETHRMRPVAPLAVPHLNREAETYRGYVIPKGSTIFVNTWGIFHDPDIYHDPQTFNPDRYMHNEHGTKPNTDTRSFRANMGFGSGRRICPGIHLANNSLLLNTMNLVWAFTFDYATDPSSGQPIPVNLFDYHKGILTAPKPFRCKISCRSSGHAQIIEREFREAIPTFQRFEGNLSVEDEAWLKATRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS81</accession>
    <name>A0ABQ8VS81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_55623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF6">
        <property type="entry name" value="PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="15"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="200" mass="22146" checksum="10565ED390234D8D" modified="2025-10-08" version="1">MVFIAEQERVEGFTHVLLITTGSVASVKAPLIVEELLKHEKVKIEVVATQPSLTFFNVDNVTNAGGRVWVDQDEWKSDYKIGDPILHIELRRWADVVLVAPCSANTLSKIAHGICDNLATSLLRALSPSTPTYVFPAMNTLMYEHPLTSEHLRVVQEVVRYTVVGPIGKGLACGDVGLGAMTEWRDIVQIVVDRFKLIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSI7</accession>
    <name>A0ABQ8VSI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_707063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1021" mass="115608" checksum="53FCD36CDAEB79DE" modified="2025-10-08" version="1" fragment="single">SLIKAASNLEIRLHDLSPSQTPVEIQSILGTVEDGAEMLRQQVASDGSAIVSEEAQKLGAMLDSVEQTVQIWRQEYPDTSPVKINNRKCFFDPAADKNTPTVIAYCIALVACVFEQTAQRGATFLLKMLKLFGYSFATLGGRSLNREQEAVLASIPESIERLEKKFNLDIECVPYAVCPKCSCTYTPSYPNNTPNLVYPPLCLERKAASENLCNEPLLSHGKPLKIFEYYPFFDWLGKFISLPGIEEYGDKFCENIDKHLIVPLNKVHQTDGHFIHEFCGVDGQPFIAGRGNEGHWFFTLNADFFNVEGNRIRGKTSSTGMMAMSCLNLPLNIRNDHAYLYIPGIIQGPHEPNAVDAEYRHYLKPLIDDFLVGYTWGVRPYATHRTHGSSSYPRVFCLALALALMDFKAARPFAGFLDITLHHFCYICDCWHNSHLGRTDYENWQPIDDEFLRKGAELWHDAVEVKLCKAIEDLFGTRSSELWWLPYWQASRQLGVDPMHIFFLILMQRYFRDILGLDNPDELKKTLKKPRFRFAFYHEFTPPPSLSSLAANSSGSQEDVFHSATHIGNIHRLLQQPLVSGQEDLRKALKQSNGDALAYVCTDIERLPVDKFAKDDMVNPLILWRMSKPLEQMQSIKIDSSGLLQRVQQVVCEVITPAWVKSPPADVGLSKAGTLKAEHWRTLFSIHVPLAVMSLWQETSPLASASASSMTSVVDTTMHLTCASLVMTKHTLSLERRNLFRHLLRLHVAGLKQDFPGWIFPTHHLAFHIFDGMEYFSGVRNWWNFPFENLIGKLQRIPINHIIGKFECTMHHSFCEGANFRQWLLQSNSLPMLQYCQQLMDKAYNFNHELPATPEDDVDDSVPDLPTVPELVENNFAQPDSRYIIPPPSNLKKLLGAVPSECFSRIPRSKGDYTIPGEGALGNHYICFQPEGVYHPGQRWLAGQIRHIFRQMQKGPIKLAIQRSLSTTALHPFGDFWANGFEADMVSSEFSSNLEIVNLNQVAGHSARWAISDNQVVVVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSV3</accession>
    <name>A0ABQ8VSV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_893659</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019189">
        <property type="entry name" value="Ribosomal_mL41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09809">
        <property type="entry name" value="MRP-L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="160" mass="17692" checksum="C4F4F811F03110B0" modified="2025-10-08" version="1">MFPTVARFSKASRRPLTTKRGNKDYYKGTRQAFLPGGHRTGAPGKHVVRGKAKYRLLDEKVRVFVAPPLHVIESSPLKPYVHTSVRHTKSQGLTPHGKFETVGGLTSEHYFKLLRTTAAEQHKRAKIGQLVETGAQGAVTPDGQQNPTLLNKAMETLGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT82</accession>
    <name>A0ABQ8VT82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_814354</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF57">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="113"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="214"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="34628" checksum="EC0ED1B309BC9546" modified="2025-10-08" version="1">MAGDGVLDTNHIRIVGAVAGIGSGLTKVTVGHGFDTIKTRLQCSPGMYRGAFDAFFTIIRKEGPLALYKGATPPAVGWAAIDSLLLGSLHNYRLFLIRNGMTEPTPISGIPRLTMVGHGLAGIAAGITSTILATPIEHIKVKLQLQSQRSISDRQFKGPIDCIRQIVRVQGPLGLWYGFTGSVAFRLNFGFMFLSFEGLMRVFSSLKGTSFEMSTGTANFISGGLGSFVFWFFAMPADNIKNRMMSYPHPLQYPQSSAALGHRPSFWATARSINSQHGLPGFFRGLGPCFLRAFPVNASAFFVYEGLLRVLGAEKTRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTK0</accession>
    <name>A0ABQ8VTK0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_814741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052925">
        <property type="entry name" value="Phage_Integrase-like_Recomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605:SF3">
        <property type="entry name" value="P CELL-TYPE AGGLUTINATION PROTEIN MAP4-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="39393" checksum="8C55E2F8B108332C" modified="2025-10-08" version="1">MVNIRSNLTAIPSHSAPTRLSARARKLINASVTSKTQNRKRNNIVKFLDWAYQQHLHARDILPASEVILCEYAAKFGGKLAGASVKAKLSAIKGWTVTKGYAWQGGDWLRKVLAGVERSAPPSSFRPEREPVKKSHLSILHAELDLTDKNGLDCCIAAAADLMFYSQLRAGEILPTNSSLVRYNTKSMPRVCDLSKPTSSGSKQLFLPRTKTSQQRGEKVMVPVQQGSTNELTPSNPLFAYTDTNGTKRILTKTLFLRRCNAIWKHHGISRQTGHCFRIGGTTYYLLAGVNPDVVQVFGRWKSSAFLKYWRNLESLASLHLHRHHSQQSHFSRVSTENVTRRRHRTIHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUK1</accession>
    <name>A0ABQ8VUK1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_914954</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="8">
        <location>
            <begin position="14"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="9">
        <location>
            <begin position="234"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="9">
        <location>
            <begin position="479"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="394"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4500062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="646" mass="69619" checksum="DE039B91C4974AF8" modified="2025-10-08" version="1">MTSAYLHATPQSILNDIDAQFTLHPALLTDLTDAFLREIKVGLEGYGEDMAMVPSFVTGVPDGTETGTFLALDLGGTNLRVCQVVLNGDKTFQLRQQKYKVSDALKTGEASVLFDYLADSVDAFLTTHPPESPESLSPSNPFPSSDSSPNPLIPDVLPLGLTFSFPVEQTALGAGTILTWTKGFSAKNAIGHDVVRLLQDAFDRKHLHVRCVALVNDTVGAMLSRGYTSGTCVLGAIFGTGTNGAYLERIDNIRKLTSTNSALYTETDTGYMVVNTEWGAFNNTRTHLPYTPFDTALDRTSINPRFQAFEKFISGMYLGELTRGVLLALVDAVVRCGEEETQTPDEGETTKHGPKYTKNQSLLFNGKSTRVLNEKWALDTSMMSEVEEAWEGGGEFSVGGDTPKSDEDVSVNDTGRGTMGITNSGLTDITNGSGGGQTIPNEIGENPLWNGDDGDYLPDWEVLSGFGASTSNPSTSNPSDTTSIINTKLERVRQVVVRRLGYEDAEVGLRDAAIVRWVSHLVARRAALLSGVAVAAVLIQTGRAGMNAVNGLNGTNGVNAVNVEQGEKEEETIGIGVDGSLIQHYPHFERTMRESLRCILGPAVERRVDIGLAKDGSGVGAALCALQALKQEEQQQQQQQQQQQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUK6</accession>
    <name>A0ABQ8VUK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_574313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018824">
        <property type="entry name" value="Conidiation-specific_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10346">
        <property type="entry name" value="Con-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="12892" checksum="4D7BCD39A4094B1D" modified="2025-10-08" version="1">MPLFSTRRHHPHPASHSHSNTSRRRERYYHRRDPDHVAGGYRAALANPNTTSAGRRHAKHELRAMGRSTHVPFMTKVKRTLGIRSTPRRKREQEKHYEREHRLRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUT5</accession>
    <name>A0ABQ8VUT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease H1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease H1 N-terminal" evidence="1">
        <location>
            <begin position="112"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="169" mass="17786" checksum="3B52FFBD034B3D88" modified="2025-10-08" version="1">MSSPNFVLPSETVTSLISVLQQLTHTIAQQTQASHDIGSQRAQYHLQSSAHPLKDAVIVPAKTVTIASAAAVNIAAAATAAHSSARSAQVEVSEGEPVKKPDTAYHHRVGKKWYSVTAGLSVGIFPSTSFAQPLVLGVSGGLMRGFPTREEAQADFDLAQKNGLLCIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUY6</accession>
    <name>A0ABQ8VUY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA ligase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_529830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="T4-Rnl1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T4 RNA ligase 1-like N-terminal" evidence="1">
        <location>
            <begin position="101"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="462" mass="53429" checksum="5ACE5CCEF57FE736" modified="2025-10-08" version="1">MITHSAQCSASSHIIATFIYNDPGFCRSVHKSVPTTMSSDARTSTTIDPSRIRKYTYPQKIKGKDLTLIKSSPHPTLPIIILNYSNDTERSSSWDDLTMAARVLVVERNTGRVVSRAFSKFFNWNEKHAYQLSSADAAGHPRDEIVSTTAEEKLDGSIITLFYYRSQWILTSKARFDSVHVEMAQEILKEKYPGIIDTRRLNGTLPRDKTYVFELIHPKNPTALRYAYKDLVLLSVIGMDGSEPPQDFNWSIYPFPRPKMNDINITDLDAVRRLNRVNEEGLVVKLYLKNDPVHPQRLKVKFESYLDLIRSKNYYTPAELVGLYRKKREMIYTFKEEEVRRKMKAEKEIYFEGVRRIADDFGGEKWVNGLIEMWNEVETVFVKAEIALRKIMDRLKEKEKFGDHVGSANAEMRRRFAQTIMKEETMVKHKNVLFLWFSGAPIEEQIKAFTASVKTREKGGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVB5</accession>
    <name>A0ABQ8VVB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_893022</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="566" mass="63498" checksum="07A0D9D35C509154" modified="2025-10-08" version="1">MPIQTPYVTPHILHKNYAQSSDAELYSNLIGRELEFFSQAGFDMDKIYLKRNAPVAQLYEDAIRNEGAILSSSGALINFSGKKTGRSPKDKRIVYEDTSKDDIWWGSVNIKLDEHTFEINRERAIDYLNTRDNVYVFDGFAGWDPKYRIKVRVICARAYHALFMNNMLIRPTEEELANFGEPDFTIYNAGQFPANRFTNGMSSTTSVEINFKRMEMVILGTEYAGEMKKGVFSVMHYLQPVKFGQLSLHSSANVGIKDNDVTLFFGLSGTGKTTLSADPNRLLIGDDEHVWSDSGVFNIEGGCYAKCINLSAEKEPEIFNAIRFGSILENVVYNPLSRTPDYDDISITENTRCAYPIDFIPNARIPCVVDRQPSNIIMLTCDAFGVLPPVSKLTPEQASYHFLAGYTSKTPGTEDGVLEPIPTFSTCYSAPFIVLHPSRYATMLAERMSKNNVDCWLINTGWTGGKYGVGKRCPLKYTRKIIDSIHDGSLAKTLADGKHENFGTFNLTIPTEIEGVPRELLNPEVAWSDKDAYNREVKKLAGMFVKAFKLYETDVDRKVLKAGPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVQ6</accession>
    <name>A0ABQ8VVQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_787706</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046851755" evidence="4">
        <location>
            <begin position="30"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="889"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="918"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="922"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="947"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="956" mass="106219" checksum="D5DCB8CBFF46695F" modified="2025-10-08" version="1">MAARKKTCARKASWLAFGLVALAAVNSYAQEPTTEVASQSGPEVAQHTQLQGGTAASDNTPSTVSDTQKHDEQAAEAFRAYKQASYTLSTLTAHPPAYTYDATAHASNSKSLLNSFIPTLQGRGPIGSIYRILYKIQQKLGSHKEQTTPKRQTEDVHPKAIKVVDLLQHSAELGNMDALFTYAKISLFPPTPHFIADPHIAFKSFSAHAATTGNATSQSYLAFFYATGYHGVVQVNPSMAQLYYTFAANGGDKGAQMALGYRYWSGIGTLEDCKRAVDWYEHAAEHSMAKFLSGPPGGRTLPQTHTRLSDLDGGIYGYGASVASTGMNVNRAAIKAGASRASGETWEDILDYYLFNADRGETDFALRLGKIYYQGSIYASPGGIGSGSEGVGAIPRDFARAKHYFEQIARQVWPRDPSNPLQHKAGAVPRDENLPVGHAAASAAYLGRMYLRGEGVKADPIIAKLWFERGVVYGDRECHNGLGIIWRDGLIPGLKPNLKKAMDHFMAAANQDLAEAQVNIAKIHLAQGDIGPATTYLEAAVRLGSPFEAYYYLGQIHASQTTNPMVPSNIASSSCAMGVSFYKIIAERGSWDDDFLREAEVAWARGTDESKEIAILKWWLAAERGSEIAQNNLGYILDQDKSILRFTRFSPMTPSNDTALLALTQWTRAAAQRNIDALVKVGDYYYHGLGVPDEKESFRYEKAAKYYQSAADTQMSALAMWNLGWMYENGVGVPQDFHLAKRHYDLAAQTNSEAYLPVFFSLAKLYVRSIWHTILGGKGGLNIWFDEEDSEIQLEYTDRVPERELESVSDQPSSTEEQIFYDDEGPWYLGKARDEFYRRRNSQSRVEEEDDPIQWARDRRHAEAREAEYGGEDYLDAGLRPDEDDDDEYSETMLLVMLCVTVSVLIYVRTRIVRRMRHDQQQRQQQQEEAVAEAPARNGMFPAPGDPARDEWAMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW39</accession>
    <name>A0ABQ8VW39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_809922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="22246" checksum="A6E062275F733A03" modified="2025-10-08" version="1">MSTSTSMKESWGTTQTIVRIEHPERYSGLERIMLAAQGDLQRLLSAFFADIINVEVIYATNTPRTAPASPSSPIIQTRKVLLKCRSVVVCTATSTVTLTSPECERLILDEKFAIGQTFRQMKQVPTFALKNVDVEQSPEGEEELRRTYTLTSKGIECEILEVFPSRDMFVDGEEWLKDQGRTRQWKPESDTSSGSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWK6</accession>
    <name>A0ABQ8VWK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_750764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04882">
        <property type="entry name" value="Peroxin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="506" mass="55414" checksum="181C263E46DA7BC6" modified="2025-10-08" version="1">MISYLESHRKGFQKAAGIAGGLYLVRGYIHSRLEEAKEKIELERLAQDILLRRYEQTQEDVGYTVMALLSNLGEQILEEMDVEAVIGELQMMSNKSFLEGSESMSASVSSSISNSSALSTSGLQGWVDATGAQAHSPTGYSSSEETSSVTSGSFISNISTIESEPNSSSASVASLPSTSSDPTSSRSKAQLWNSVKLLTFTRTLTTIYSISLLTLLTLTQLTILARVKYVRAIKHMSSEEDQEAALEGELGMTNMLLMALKARFGIPQQPLLKTLLPSVHELLFAPADDEDMLENSLSNTTFETLSADYVTLSYYLLHIGWKNISTHIQSAVEEVLEGVSLKTRLSETDVHRLLKDMMQRVALEGLTASMLPNTEDMVRSVLVLGGRDDHDPYSPSQGAALSTSMDDLLSETRTLFSSYHFTEVLDTCVDWAVDSLMKSLEGEGRVFASGDAEAPRVRLASILPPLASWSRTSLLALPSELVDGILAKDETRTFSAWVWAKFELEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWL9</accession>
    <name>A0ABQ8VWL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_808921</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="155"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="234"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4500782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="290" mass="31865" checksum="1A8AB3B18E0EC19C" modified="2025-10-08" version="1">MSRVALAGIKALTFYKDDLTNARRTSPIPQLMCVGKLCKVYQPEVVHCKNIGGAGLDVDWKCEADLPEALRFGKVMVSCEGWSGPGDPYVLKDSCSLEYRLVEIPRDLRNHSDPHHSSSKKTVDIANIIFTVAWVAVLLFICYSFLRSCLSTRNAPSSNTSRSSNQSGGAPRPGDGGGNGRFPGYYDDNTGRDPPPPYSKTQNEPWRPGFWTGAVAGGLADRFLFRNNEAGGRQRRQWDWEQSRRPTSFFGGGGTRRTWSSSTNSEDRGEGSSNLGNVRRSTGFGGSNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXQ7</accession>
    <name>A0ABQ8VXQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_913882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="22100" checksum="B959AC71E9C93D13" modified="2025-10-08" version="1">MSDSPMWRYEFTSSTTAIIMRSKPRSRSAPPFSAHDFGLGWELREDGIETEDLRMDPADLAEFSTVKIFRDYHPRSMYWVDSDKVLKLFSYLIDVSIIVENMDLARTRLPVPRVLRYGRSGNCSYILMERIPHTNLAVDMLQWGIQSMPWQWTQTMDYIVRELADLGLTHNVTWYQGMSSLIAMETYPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXV8</accession>
    <name>A0ABQ8VXV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Splicing factor, Prp19-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_978374</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="3">
        <location>
            <begin position="74"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1008" mass="113780" checksum="D5DDC44966E8D65D" modified="2025-10-08" version="1">MPMKKQVLKSKSMNIALRDVDISTDGKVIVAGREESGKTVLEEDEESEDESEEDIGSKVKQEESEEDSSEYESDSEEEQKPKLRFRPVFVAKRNRETIAEREQMAEDTEEALKRKEMELEERRKQSHDLVAESIRRELTEKEKEEQVPDVDDTDGLDPAGEFEAWRLRELARIKKEKEEEIRREQEREEIERRRAMPEEQRLKEDLERAQKLRDEKPKGQQKFLQKYWHKGAFHQDTEILQRHDFTEATESTMDVSLLPKVMQVKNFGKRSRTKYTHLLDQDTTIATGGFGGTAPVKAGGKSTEGGGCFLCGGPHMKKDCPQNVGPSTRQPGSGANAAPGGSRTWGGPPGQSSSWKDRDNGGRQNGDGDWKNGRDRSPRRDRYRDQEPYPSGGMGSSRSLKRRDEHDSRRSRSPRSVSRSRSPPRRKDRQNDRSYGRGERRQFRDRSEEHNSRDKRRRNLMPRAVKVAVVGTGLAGLSAAYLLSGSSTEVDFESSTLGMDSSSITLPVPGKEQKWRIDVPMRSFQSGYYDTLISLYKHLGISFRKTDFSYSFSRLIPETVYASRKITTDVIYNGNSGIAGMSIPSSMRLNEKVLSSIHAAASGAYAYGIFTLMCFKLLILYIRVLFLSIPIFRPQGVEEMTFRTWSASTTPRGFIARCTMLDLAWVEFTQDLLVPLFSAVCTAPESNVYDHPVEEFLDYIWLTLGYHHYVALNGVQEVVSKLIAGVQHVHLSSPISSIRMNPDDPTTSSIHVSTGSRVQIHTGFHHIIFATQAVRAVPLLEAFASSLPPHAKAKRRAVEEQIACLRQFTYCSTLVINHTDSSLMPDNVEDKRDLNLISLDRDAPSLVADVKEVRSSRTELEDSWSLRCLPPSYTMATHVLTPPEGYPAHLPTIYQTTNPIIEPRESRILSVATLERAVLTVQSKRALKCLNVRYSRKWWHAASPGKSGLGPLQGARRGNELEQTPGIWICGSFAYSGIPLLEGCVVSARNVVEQGIWKSEGVRGHIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYG0</accession>
    <name>A0ABQ8VYG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_807939</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 12" id="KW-0732">Signal</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 12" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044968590" description="Extracellular metalloproteinase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="13">
        <location>
            <begin position="88"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4501056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="791" mass="87057" checksum="B9A26BF561BAAB12" modified="2025-10-08" version="1">MRCLLIASILAGIVGSVQGHRAPVTARKSLGFGPIHPHAVYRSNPYQIATNGFLPQSPDADPFEVARLFIGDILGPNQDQASYKIRPDSYTDPSTGVTHVYVRQYVHGIEVADGNMNINVKEGKILSYGNSFFAGTPPSLIAVPDLRNFRHPQREYCQDLSAELETQFNVFASTQNEQAPMGDQKTSKSAAFAGPLTHLYYSNCQFDGLADDMALKRPQAIGDIGDMRPALLQFMVAATPKADVVNDILGNYDEHLNKMSVSGVNHFTPEGEQTYLFVDNVPDTVNPVKANIAYIQIPSKDGSVELVTVWKFEVEMHDNWYEAAVSAIAPHRIISVVDWASDAPIPVPDAPKESASYNVYAWGVNDPSEGNRTLQKENFDSLASPIGWHSLPFANDPSYRSVKPSNEFYRNTSTTFGNNVFAQENWEGQNAYINNYRPEAGSSSVYDFQYKPKVSDSDEAMAVAHNYINATVTQLFYTSNMIHDLYYRYGFTEVAGNFQQYNFGRGGREGDAVIANAQDGSGFNNANFMTPPDGTNGRMRMYLWNTANPYRDGDFEAGIVIHEYSHGLSTRLTGGPLNSGCLGWGESGGMGEGWGDFLATTIRSTANYSDYPMGAWAANRPKGIRNYPYSLNETVNPSTYQTLDKPGYWGVHAIGEVWAQILWLVSQALIEEHGFSDTLYPPMPLENGTVPANDFYRPAVGKKPLVPKHGNTLSVQLVINGMKLQPCQPSFFDARDAIILADEELTGGENFCTLWKAFSLRGLGTDASVQGRTPWGGGIRLNGFATPTTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ98</accession>
    <name>A0ABQ8VZ98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4112 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_809096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19660" checksum="C483187B8575E5DD" modified="2025-10-08" version="1">MSSADFQPRWTCKYRRPKNPIDAQHLYNHIRTVAFLLDASSEWLIPTFPFLGSLPFEMQFGLDSIIGAVLPGFGDAIGMLLAFYQLFLSMLFGLPINVIAIMVFYIFVDAFIGIIPFVGEFLDVAFKANLYNLRLLEKELKRSKWATAVIIPQYTDWIPRPKRNSQKFGASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZF2</accession>
    <name>A0ABQ8VZF2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_907075</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17941">
        <property type="entry name" value="DEADc_DDX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="88"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="286"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="512"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="688"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="688"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="726"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4501752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="795" mass="88903" checksum="CBBFCC938E8772C6" modified="2025-10-08" version="1">MTSQPLAGPSRPRKQQKNKKDSKYGARPTKAKKLSETQRIETLERQAMEFEAPEGLKAFADLPISENSKRGLKKAFFVDMTDIQAQSIPVSLKGKDVLGAARTGSGKTLAFLIPVLEILYRQRWGPTDGLGALIISPTRELAVQIFEVLRSVGGYHSFSAGLVIGGKNLKDERERLSRMNILVATPGRLLQHMDQTVGFESDNLKLLVLDEADRILDMGFSRTVSALLSHLPKSRQTLLFSATQTRSVKDLARLSLQDPISIGVNVGDSYSSSIPKSLEQHYLVCTLDQKLSILWSFIKSHLQSKIIVFASSCKQVRFIFETFCKMHPGMPLIHLHGKQKQTTRLTMYNKFTQSKHAVLFATDIAARGLDFPSVDWVLQLDAPEDADTYIHRVGRTARYESRGKGLLFLMPSEEEGMLAALKAKGIEVQKIKVKPSKQQDIQNQLQKLAFQEPEIKYLGQRAFVSYLRSVHLHKDKSIFKVTELPANEFAESLGLPGAPKIKFLSKEVAKQKKNTDRRVNAAKQQALEEKQDSAEEESDDGDIHPSSDEEDGSGNESEAAVTKEPPSKSTKSGGVRTKYDRMFERKNQDVLSQHYSKLIDQDVTSDEDDFITLRRADHDLVNVPLREVALENLSKRKNKLGKAKRTILLNAPITKKIVFDDSGVGREAGEVADAEDWVKETGGVEGVVKEGNKYAEAERGKMKIADVLDKHDAKEKKKEKNRKRKEREQTAMEGGREVDAYAEPSDDDGYVSPEFDLPSESEEESRPSKRSKVARPSSALEDEEELALALLRSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0M8</accession>
    <name>A0ABQ8W0M8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="4 16">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_804952</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the NSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4 16"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16493">
        <property type="entry name" value="RING-CH-C4HC3_NSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014857">
        <property type="entry name" value="Nse1_RING_C4HC3-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08746">
        <property type="entry name" value="zf-RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="197"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="261"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4501522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="339" mass="38475" checksum="1F0778F3BCFA404A" modified="2025-10-08" version="1">MVHAGDVQRLFLQAIFSRGILSENLAKVLWKKCVEAVKAADEHVEVSYSNTEEAWDEFIQGVNTSLNDLDFEFKSIQDEVDSKRLFAMVNRKDDELAQVATDYIAVEIMYFKAIVEQIMLARNESFSVSSLAALREVSAGKDKMNLTKSQAEVLLGSFVANGWLLRSKRGRYSLSSRSLLELLPYIKSTYSEEMIECTICHEVLTKGVACKRSNCKARMHYHCFKAYRRRKSTCPVCSLDWPENVTDDGLLPVGELAIRDGDDGIRRTRDSVNSDDDEEMEDEPSQTETKSRQPQRSQAGKKGKSKKKNDDSEEEADEKDATDEEEAEATPPRRRSTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W111</accession>
    <name>A0ABQ8W111_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-demethoxyubiquinone hydroxylase, mitochondrial</fullName>
            <shortName evidence="8">DMQ hydroxylase</shortName>
            <ecNumber evidence="8">1.14.99.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ubiquinone biosynthesis monooxygenase COQ7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ7</name>
        <name evidence="9" type="ORF">C8R41DRAFT_805370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + AH2 + O2 = a 3-demethylubiquinol + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:50908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="1.14.99.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="8">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the COQ7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.60" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01042">
        <property type="entry name" value="DMQH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01658">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011566">
        <property type="entry name" value="Ubq_synth_Coq7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237:SF4">
        <property type="entry name" value="5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237">
        <property type="entry name" value="COENZYME Q10 BIOSYNTHESIS PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="24532" checksum="2862C790BC2CA0BF" modified="2025-10-08" version="1">MLSSFTGIQRFPRCINRRLLASFAYTKPSLANDPATHSTPLDITDEQRAALDSALRVDQAGEVAANWIYYGQHFILGKQPVTGPLIQEMWEQEKKHLAVMDKMQLQHRVRPTILMDFAKIGGFGLGAATALMGKEAAMACTEAVETVIGEHYDDQLKEMESLPSAHPSVPLLKEVVKEFRDDELEHLDIAVVNHAQRAPGHALLSTVIGAGCKVAIELCKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AME1</accession>
    <name>A0A9W9AME1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_452022</name>
        <name evidence="11" type="ORF">C8R41DRAFT_841886</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000010">
        <property type="protein sequence ID" value="KAJ4486522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AME1"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF35">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="16"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4481347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4486522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="514" mass="56493" checksum="E00ABCC316DE820F" modified="2023-11-08" version="1">MGKGYNAAIAANPYIVGSFACIGGGLFGLDISSMSGVLTNPYYLRQFHTPGSSAQGAIVAAMPAGSFVGALAVTQLADRLGRKRTILLSSLIWVIGSILQCASVNRGMLVVGRIVSGLSIGIASAIVPIYQSEITAPAIRGRMVSLQQWSITWGILIQYFIQFGSSYIDGVASFRLPWGLQMIPAIVLFIGMLFFPESPRWLMDRERDEEALEILADVHGHGDKNHELVQLEFEEIKQQVIFEKSEGAKSYFDLLKGNIPRRVFLGSSLQMWSQLSGMNVMMYYIVYVFQGSGLTGTRAGLIAASVQYVLNVVATIPAIIYIDKWGRRPMMILGSLFMGTFLFLVGGLQARYGHWGSVNDAPVWVIDGHAAATKGIIVCSYLFVCSFAVTMGPVSWTYPAEIYSLKTRGKAVSIATATNWIFNFALAWATPPGFANIAWKTYFIFGTFNFAASIHFFFMFPETVGRTLEEIEDIFTEGHAFAPWRIGKHTGKKTLADVIGQSKEHNSIDEKEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AWI7</accession>
    <name>A0A9W9AWI7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-fuconate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.68</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_503031</name>
        <name evidence="9" type="ORF">C8R41DRAFT_777462</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O</text>
            <dbReference type="Rhea" id="RHEA:22772"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:21291"/>
            <dbReference type="ChEBI" id="CHEBI:37448"/>
            <dbReference type="EC" id="4.2.1.68"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.68" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000005">
        <property type="protein sequence ID" value="KAJ4492116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AWI7"/>
    <dbReference type="OrthoDB" id="14161at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050023">
        <property type="term" value="F:L-fuconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03324">
        <property type="entry name" value="rTSbeta_L-fuconate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034610">
        <property type="entry name" value="L-fuconate_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="8">
        <location>
            <begin position="197"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4470304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4492116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="467" mass="51835" checksum="C3E7BC20719D4E3C" modified="2023-11-08" version="1">MPKITGFEVHDVRFPTSLTGDGTDAMNTDCDYSSAYITLLTDSELVGHGMTFTIGRGNDIVCMAIREVANRLIGKDTEELFADMGKTWEFMMSDPQLRWIGPEKGVIHIATGAVNNALWDMYARSRQKPLWKLVVDFSPEELVRSAAWRYISDAITKEEALDMLKKIESTKAEREAKVREIGYPAYVTSAGWLGYSDEKVARLTKEAVAMGFNHFKMKVGADQANDLRRGKIIRSIIDDPQYLPAGTHPRDPNSEDLKGKNAGPTGSVLMIDANQVWDVPQAIEYVKGLEEIKPWFIEEPTAPDDVLGHAAIRKALKPHGIGVATGEHAHNRMVFKQLLQAEAIDVCQIDSCRLAGVSEVISVLLMSAKFGVPVCPHAGGVGLCEYVIHLSLIDYIAISGTMERNVLEFVDHLHEHFITPCSINSKGRYNVPTNPLEGYSIEMFQTSIAEYEWPNGSYWLSAKGKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW11</accession>
    <name>A0ABQ8UW11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_872407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000161">
        <property type="protein sequence ID" value="KAJ4463520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="36034" checksum="7238DE3D147748CE" modified="2025-10-08" version="1">MSHTVSPMATIHLRESTYNLIQRVSFKVQQCILSGVLYNRSECNLLHGLRLSFGLSVRSNPIPSLKFSSFNTIYPSSGLSQIGPHHCKHYDISVSLTFADSQSVTQSSSARVVARRKAKLNVYFREECEDRSVSDEDQKVLAAHFVSFIEDHIVKTTPEYEVAGAGFRLQDVFDADHKAWEIFRAQNFPYESTSLIKITFESIIKPAPKNTKPSAPLTPLLNKTVKDIYHTSHPSSVSNSQGLSKQMMSILDGNVKSSSPTRKVGWKKEKPSLLKGVLVSNANKISTTYEVQPTESRSSNTNSSAGNLLQKETMFGHFIQSAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY03</accession>
    <name>A0ABQ8UY03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_871895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000127">
        <property type="protein sequence ID" value="KAJ4465438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="49620" checksum="65E88E1AB41EA861" modified="2025-10-08" version="1">MSSTPVCSPSRTPSPLLPPLTALGEVPSPDPGSDGEVEEDQLAFTLESPSRPQLQLFETVFNTGKPLSGYCQDNPLWLLLAEVASPCTNCVKTPGRCKVLPNSPRCTNCTSKKTCSLGKILRYRYFARRCNQDLAYSRRFLELHGTSAHQSTWGIPLSTWREYDAALHARTSSTSTLLELNMLDEKDTVEADQQELREFLALQQGEAVVAAKRKRDHSPVPVAGPSRKKVRSDVSKKRSRHRSPAAAAIPDSPLHIRLVVPSSCPVVASSSPPVRPRSSPSLMEVLHRDLPMQGPSDLVRLAAAAEVHPGLVQQAGSSSPARTPIKGTGQDLLSSTMPPILRPALVPRNPASHPYRAENQRLAARVRLLESQLADSQRENSSLTSALRDTLHALESRQREVEQLRSSSQEFLQHQEEYRRIVDQFNTLDRALSGPSDQVSCRTTVLTLSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY15</accession>
    <name>A0ABQ8UY15_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5648 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_803862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043708">
        <property type="entry name" value="DUF5648"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18885">
        <property type="entry name" value="DUF5648"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046538348" description="DUF5648 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5648" evidence="2">
        <location>
            <begin position="31"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5648" evidence="2">
        <location>
            <begin position="218"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="433" mass="46474" checksum="6E17F8C899324AF9" modified="2025-10-08" version="1">MHVLSPTVFSILLRVSLSLADTCADTSSLVPFLRAFSGSENDHFYTTNVSEMKNDALAGGVYVFEGESAFLWPTPEPGTVPMFRLYNQNSSDHFYTMSSDEVPEMMNAGWAYDTAPNHTAGYVYPYSICGAAPIYRLFDPTSVDHFYTMDVVESQNAVQAGYQDQGIAGFAILPSANGTVVQSSAIPYLLPSTITASPESQVSATTSSSCANVANAVPLLRAYSIGGTDHFYTTNLTEMNNSVAVIGYSFEGDATFLWPTQEASTVPLYRLWSFSSSDHFYTIDKNEVSEALAQGFAFDTEAQNVGYVYPYSICGASPIYRLFSSFGSDHFYTMNQAESMSAPGYVLEGIAGYALLPSADGQRQTSASPFLLPLSLEVLPVSITLSPIPAFTTSIAIDTGSPSGLPSTAGVQSTVSRHVVLGVTALVAFWIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYM2</accession>
    <name>A0ABQ8UYM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_780908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000119">
        <property type="protein sequence ID" value="KAJ4466033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF115">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="121" mass="13427" checksum="3CB81133B8390E8D" modified="2025-10-08" version="1">MQPARADLLPPKDDPFTLEELKKYDGTVEGMPIYVSIKGDVFEVTHRSDVYGAGKSYNIFAGTDGSKGLGMSSLKAEHAVPNYSGLDEKDMKTLNDWHAFFLKRYNIVGRVSDLPDAVKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZC2</accession>
    <name>A0ABQ8UZC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_856396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="8422" checksum="2481FB8536593073" modified="2025-10-08" version="1">MFVKFHGTPFMLLLLIIFIRYNWHSREKYEGPPVELDTLVIVCTIEQLRSTGLPTWNSYAFSKNNRSLERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V045</accession>
    <name>A0ABQ8V045_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial ATPase inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_855400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="8474" checksum="52C722964E99E0E6" modified="2025-10-08" version="1">MFSRLAVRRAPRVATVSVRYSSSAKEGSVAQSRGFKERESAVENEYAHKQEHAKLMKLKAEIELKKIELVRADGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V081</accession>
    <name>A0ABQ8V081_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="277" mass="30336" checksum="25BFF489002626EA" modified="2025-10-08" version="1">MILPLRRTSVGSSICFLERNGQTDSSIRVDPDSSACTCNLNNPEFPFCNEPEDTTTLSQTSSSHDPTVTRTITQTATASSPIVESTSADSAHSLNTLSSISINEYLITKSTYTQPNFHGQFKWHKLNGNPVTEIEYANHWRIKHTGAIVGGVIGSVALITAILGVFYIRRRSKNRNGALGSSLESQPPLARKPVPVILTPDPFTLKYLESRRDVDIFEQGSSTTTVNPLLSDGRIDELMRRMLTLETLLAAQSPGPQRSLPIVTPLPPNYTNVNGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V199</accession>
    <name>A0ABQ8V199_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine nucleotide binding protein, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_859047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF360">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4464966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="494" mass="56512" checksum="798B1F34F21E66DF" modified="2025-10-08" version="1">MNAADFDPLTLAIAPPPNETPTARADRELAEAEALRISNEIDEQLRKERENEKKKKRPVKLLLLGQSESGKTATLKNFQLTYAKREWIAERNNWRAVIFLNLVRNVNNILDILNREMAAASLPSPDYIGSSDESSEDINSSSRPRLKFKEKHRLLKLRLGPLRRIQTDLERRFGATALEPQSTSITTAAPFGSEESQSSRQSSKEFSINSSNGWKSAFEKIRAMRAAARADGDAHALRRLQETDDEIAEVIAGCRDDVKAIWEDPTVREMLSRGKTRVEDSAGFFLNDVDRIAVSNYEPTDDDVIRARLRTLGVQEYRFIFEHGRTAGQEWRLYDVGGTRSSRAAWWPYFDDVNAIIFLAPISCFDEKLAEDRRVNRLEDSFLLWRSVCDCKLLSRTQLILFLNKCDLLQAKLQRGVRIRDSVPSFGDRRNDISTATRYFQQHFKEILKQYSPVQRSFFVHLTSVIDTRSTAVTLGAVEESILRDHLRRADLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1M1</accession>
    <name>A0ABQ8V1M1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_985364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000134">
        <property type="protein sequence ID" value="KAJ4464826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="129"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="631" mass="70313" checksum="59DBCCA77DCAE6F9" modified="2025-10-08" version="1">MSKDLELEDLKKPSPSPSRIPQRTFLKFVLICIFLSTLWISNYIPLPIYHHEYSVCSESGSIYTVDEVTPQVECISIVGSRISYTGSSKELQGRLYRRAQAVSWLQRWLVSRLFSRVSHKISYVNSDAIIVPGLADAHAHIMINGFKMQLELDSCKSLAEVLEQTKAYIYSHPDIYNNKSQWIEGGGWDQTKWPETGFPHAADFDTDPLLRGRPIALHRVDAHASWVSTRVLEIMGDLPTKVKGGSIVRDSSGNPTGIFLDNAMSLIPVPEWTDEQMTTFFDTTMNLALSYGLTSIHDAGSSPKIIQFMKKQAEAGNIPMRLYIMGHVSSDEYWGSQIPRLIDYGKHGHLTIRSVKLVTDGALGSWGAALLEPYSDKPDTSGIMRSTPKTLFNLVKQFWKDGWQVNIHCIGDRANHVVLDIYQELIEMGHNETTTMIANTTGEGELMKANVTEWRPRIEHAQIMTMKDLRRTNELGIIASVQPTHATSDMWYAETRLGPNRIKGAYAYRTLLYGSPKHVIPLGSDFPVESVNPLLGFYAAVSRLSVDGTSPHGDGGWYASEALTRAQALKGMTLDAAYASFTEHELGSLTPGKKADFVILDRNIMQVPFKDILKTKVVATVVDGKVAYGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1U3</accession>
    <name>A0ABQ8V1U3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_67125</name>
        <name evidence="4" type="ORF">C8R41DRAFT_923990</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="89"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4474224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="255" mass="28977" checksum="1BB99A6AB78D8A37" modified="2025-10-08" version="1">MGPGALMPLSTSKPSTHLSKSSSNPQTPQSNRKLKREFAEVNLPISISPGSKRPCPEPQREENGQSNKENEELEEATNSKSLPSLLATVDRLKAKIWQLELQIQAQEAAAKCQEQQISDEHSRYLQIKIKKVKLEGQLEELKQTDQKDESEAVSKLAEMREQIKQRDERAEKDAAKLKQYEELISSMEMEMIHMKKKSSMVHDLCRKAGTILQAPYTFANNISLKDIQDVIDYRPHSTKVNRNPFSDSTEECPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Z3</accession>
    <name>A0ABQ8V1Z3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_889912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="23"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="738" mass="83374" checksum="28A146C2493FAE48" modified="2025-10-08" version="1">MSENTRSNLSPPRRYDDPSTKIWSLYLDQAEKNNERITESWKGDMDAILIFAGLFSASVTAFIIESYKDLVPDNSDATVILLAQIYRELTNDTTLTMIPSVSKALDANSFVPSTSSLACNILWFLSLSLSLTAALSATLVQQWSRNYLQATVGRDIPYQRARISTYLYEGLIKFHMKSIVTAIPMLLHASLLLFFAGLVLFLQPVNRGIGYLIFGLLSVTAILYVLISILPTFYFDCPYGSPLTKIWWRILCSLQLIVRETSQGGTSPVPPDCSLAKVREWEATDISYERDERDFRAICWTLEYSPDDSTLELFASIVPDVVAGLDYSAKLLCRRLLDRNDPSMRLGFRLTRLLANCNIDSSSAWAKRRCISTLSAIWSLTMMTLPMPHTPYSQPDLQPLVTRGMLRFDEHTLRTIEIIQRYIPDASPHCLSTAAVIARSLLDMFSDHILDLETGLLNYTRTGNLPERYQKLGLHALKNTLPQSDPRSMIDRIDKEAWDIQQRFDTEQGSMLLASAYVSLDSLSRHLQDLVLVVLIGDEEESLIYVKEILDRQNRFQVLLRQAGFLLILEFLENLLKGSSLPHEAFNTTRRLYLQLDLDSSRQPFSLRSQSRLIRYLDDALHLHNSHPKNRLPEGIINIALGLLRGVTDLECVSKAKGIVTTYTKVCESAPNFEAAREALASLNSMALPEHIRPKEVLDIFSEHVYSNTKLTRAASSDMSTSITSKDGDHQFGRIFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2P7</accession>
    <name>A0ABQ8V2P7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_851522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4471011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="228" mass="26026" checksum="FE54DE8E038366CB" modified="2025-10-08" version="1">MKGHHVKDQENPKSIGNITKDITDDDEATCSPGSDIDFFSMSLIEKCKDQTRNIQAEYQELDPLLWQNIKILCNTLKEIYEFTDTCVHRNIIIRFLCASADAERVLEYQGNIKKALDMFNLRATIMTQQVIMHMCTQQNLLSSETSVFPEPGSKTPYFLPFTGTTTGNACSDKNRTSKTSSCIHTMPQLQMSLMTQEHTLFQSYLYPLPEPALLLVLIKKHSQQFQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2R0</accession>
    <name>A0ABQ8V2R0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_926079</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="280"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="433"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="572"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="652"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="674"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="736"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="528"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="965"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="547"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1003"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1049"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1087"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1102"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1142"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1158"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1199"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4466601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1238" mass="133875" checksum="B86488E74FC04C2E" modified="2025-10-08" version="1">MQNPNGNHHAPGQSAQPPALYLEPSISTTTVVTTTTTTTTYAPIPLPALPPITAPPPKDGKEYPLYNAQLPHSAREFNIVFPGGKKALFRDQSEGIEAEGSGTNNAMGSSSLGEGELTSGKGWRMLPREDSHSNSSQSPPNVIPVVGLNEALEGYSTKKRDRGHEFEFESIAMEDTPARKKARAPPSPLPSPHGSPPPDAKPPVGWHSDPQTQIVQAPTPPTPFEPDLSMTTLLALPSLLNHFTSLPESLQSHVLLMLLRHSPLPVLRTLHSVLHPTLARDFLTLLPPELVSHILGFFTLSALGRACRVCKSWRGRIEGDKVLWRDLLMRTGLWFGGETEANFVKMLMKKRRNAIDSENTLPLAHPYKILFKSRYLTYTRWINNPSPKHISFHAHGHSVVTCLLFSQNRIISASDDHSIHVYSPTTGRLLLSLDGHEGGVWALAAYGNLLVSGSTDRTVRIWDLQEGRCLHVFGGHTSTVRCLAIVKPEWITHPDTGEREKWPKRTVVVTGSRDHTLRVWRLPKRGEREFDSRLPPSPSGHALQANPPLPPSSPDISDPPDPSLNPYHMHLLSGHTHAVRALAARGRTLVSGSYDCTVRVWDIPTGRLVHTLTGHTQKVYSVVLDSRDGTWGSEGWGYGSTASGRGSDGRAASGSMDGTVRLWSITTGECLHVLSGHTSLVGLLGLSPSFLVSAAADSTLRVWDARLPSNDGSYNSRTSFGPSPSSNSADLLRGVMTGHTGAITCFQHDEWKVVSGSDGTLKVWDLRDLNFANTSPSTLNVAGGTGTGGWGIPGGGWGPAGFGAIPGAAIGFGGAAAPGPAAAGAGGAAGSGAVPVVRDLLIGITGVWQVAFEGRWCVSASNRNDVTVLDVWDFSKTEIVTGDPLSNTTGSGIIEVNEEPEDRERESKEGNVWTWEDEEWVGEPPGAIYDYEDSDVEDSDVEGDAGIVGRYEDGDIELISVHEERDDDEDDIVYTGRRSPSSGRQESIIHPPYHVSRPPSKVYPSSSLINAETQTAPRTRRTTRAMSEVSRTSERSTRSRGSNSRMDVDVEIDVDVELMPEVPEEPLHEQEADIEGDGEYRNLADGLEGDDRDAELVEDMMEIDRDFPESKRSSQIHSAARHRIASRRLEEDTNSLPEASTSRHRHGPARSKRAFTPSAPSRQVSGSSTKAFAGSYVGRRGHGPSTSANRAAELGEGELTSSGSNSAADTPGDDGEVRMSSPGVASANTKGNSRRRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V397</accession>
    <name>A0ABQ8V397_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_856603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="249" mass="27975" checksum="6F5726D0D6D728DA" modified="2025-10-08" version="1">MNTDDQGSRMDLTVPVHRDPPRTQSIPYQTPISVPFRPTQHTPAYMRANSHATSPMDTGPGQLIHNFSPSHSLHSSSHPRNSPIHTSTVPLLPSFPSVPTIPQSVSETWHNHIVPTFHNLSHNFMTQNMFHYRPLPSAPVPSSNTFIPESYTPLDSPNFLPINFVRSPVSVPPASVCLPSRVGSRMDHSHIVERAPSRIMHQPRPHRIVDLNHISTAAQLIPETQSAPAILLEFPQETHHPFHHHPVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3A5</accession>
    <name>A0ABQ8V3A5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_622633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="41905" checksum="AEB07588DD070D75" modified="2025-10-08" version="1">MPLIPNIFVVNMPTDEEQYVRIMTILGNTMYIVSFIALAAILSTKLLNKRIKRTITWNFFIASWMLHCVTFFLSMGHQIGSSIPPFGLCLVQAGMLYATPAYNACVSLALLLHLHSIIVATVRGVNHSSSKRMQVLVWILLISPLVVYVAVFLMTFIMVFQDKSLLQRDRTFYFCNVKDEVGIWTSSIIVFLCALAFITYEIYTIVILWKNSQTFRAMNPHSRDRIFRSIVIRIGVFTVFPIIALFLSVILSFSAADSWTPSSGMRINVVDASLPLACALIFGSQEDLLNVWMFWRESSPYRSTQHSQTRSSGPEHLRTGGRSRILLDPVVPRVGVKVSTTRIQDRGDGWASKSPIESDIELHKDAKVESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V645</accession>
    <name>A0ABQ8V645_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_846161</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07896">
        <property type="entry name" value="Adenylation_kDNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08041">
        <property type="entry name" value="OBF_kDNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029319">
        <property type="entry name" value="DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050326">
        <property type="entry name" value="NAD_dep_DNA_ligaseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006592">
        <property type="entry name" value="PRK09125.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810:SF1">
        <property type="entry name" value="DNA LIGASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14743">
        <property type="entry name" value="DNA_ligase_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="9">
        <location>
            <begin position="48"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="SWIM-type" evidence="9">
        <location>
            <begin position="449"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="8">
        <location>
            <begin position="626"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="500"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="786"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="389"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="791"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4476256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="818" mass="90334" checksum="2E8762C28C635DAF" modified="2025-10-08" version="1">MISVPSTFTSTIIMVNDKLAEFNGIKPNFTLEEGEEKVIRPKFIALTFTVKRNSEHFYCTCPAWRNQIGTPVNARSCKHLISLLGEQYEEARLEYMNPGGPPLKGLPVRRPRAQNSQNHSIRKSPSNPSPDSSGSHNKVLGATSTSKSTKPISVPSSKPFSTSAAPQNAKPLSSNLLKVKVQAKKREKRGKKRNDDDDDSMDVDDDENNMDDIGDLDDDVDMDEDENDDVKPTKQSVVPAKRPVKRAKEDPDLEGDEEEAENSPIKRPKTRSSSHKGKSPVKKPNKVNESISETEDDSDSTSEKNNKKSILVKGKGKKISNQKPAPPKAKAPAKATSKPSSRKRTRKDESETDNDDANDSDNQADRKTPSTSKKLAPKGKPASKRQKVEEEEGDEPEDNDEGDDEEEEEEDDDDDGGDELASIKGIKPNVLMEDGEEMEVQSQTSSSTYKVKRTWDHYYCTCPAWRNQPSVPVNARSCKHLISLLGEKYEAARIKLKNPDGAALRAPKSKKKSSKKGKNTGDDDDNGDSSKTDVAVLLANSWDVDKGPDPTGWWVSEKLDGVRTFYDGKRMYSRLGNPFTPPQWFLDKLPKDVTLDGELFGGRGEFQNTVSIVKTMNSPHWKGITFHIFDIPSLSTQPFEARLEHLKKLFAPGTGSYASDKVIVVEQEKAKSRKHVLDKLKEIESLGGEGLMLRKPGSLYEGKRSSTLLKIKSFYDAEAVVTGYKPGKGRNAGVTGALKCQMASGKTFDVGSGLNDKQRKSPPKIGSIIVYRFQELTKDGVPRFPTYLGEAADKTEPKDAVVPDHRKAGAKKSDAPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6E7</accession>
    <name>A0ABQ8V6E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_544874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="32127" checksum="91EC9600D702417B" modified="2025-10-08" version="1">MAPYNHPKSLQKTKSPLFSATTFKRSPLLYRGRVPARRNPPESRSKHVLPIIPEIFGSPDRDRRRSRLNTVYYDPFEQQEDVDEVFNEEERPTFTWENEKTLVSDLLHDGYEQEHEDVKLSSLADSIQAAFSVHSKELLDDVADTLVPAVNLVKHGHQVLNDQVDDSFALGVFEFDEACKKLEAVTISSHNELKKAYRTSQVRIQDLLKQLEEACTRRDRLWVDFEAALDDILNPATNSLKTLPIRMERTIATLEKQSKQIGKDSGSKEKYLKGLLSKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V722</accession>
    <name>A0ABQ8V722_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_887441</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 9" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="11">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="12">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4476129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="150" mass="16690" checksum="76DAA0F0EAB5461F" modified="2025-10-08" version="1">MTGKSGKSGKLGKSGKSVTGKKTILLAKKSRKNRSERAGLVFPVTRLRRYMKVINADKRLTSSAPVYLAAVLEYLVAELLELAGNACRDHKKKHIKPRHIQLAVRNDDEINKLLKDVHIMEGGVIPGIRPELLPKARTASYYHAYDSQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7M1</accession>
    <name>A0ABQ8V7M1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_844404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="108" mass="12044" checksum="C83523BBFBB82307" modified="2025-10-08" version="1">MSCSSSASATPLCFFFKPAFSLSMIDSLNPPILHEKPSLASMTGHMVSETAMAGLRLIIPYHGLSLNIMIAINLSWLRFGYPWQFLRPQSYSLPLLSEQNAQHQFVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7V6</accession>
    <name>A0ABQ8V7V6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_510722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4478535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="50577" checksum="C76E05418E336AD2" modified="2025-10-08" version="1">MSGDEEEIGTLIIVVLKAQNLNDKHFFKQDVYAQVTLNGITKKTKIDYKGGQHPVWDSELRFSVKKGTAKKYRELEVSCFAKEHRDDTLLGEARVDMTPTLKSGEFDEWVPLQVNDVQRGDIYLEITYYSNGPAPPPSAPLTSAHPPSSLLAPPTTANLSRRPSKMSPADRLYRPTSSVNLHASAQQQQQQPGPRPPPKEGSLPIPGSYPPTTAVSNTIPAAVPHALKSGLAAVPSTLKPGPVAVPSTLQPGPTAAPSKYTSGPTRISPKQQQLPLPATVPPGTGRVPQSSPPAVPSILRPGNPQSDPHPSRRSSASPPGQSHLGHSATGPVPYIATHTPNPYTSSSPAPSNYNHNGALFYSSSTPVPVSDGSPIPFASPSTPVPPSSVNNRNSSLSYPSNVPSIQPHTHRQSSNPSSILDWNSTSQPEGPLSFPVPNFPGAPSIAVEPTSNSSCAPANRIVFAHSTTAGADVEFGQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V812</accession>
    <name>A0ABQ8V812_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Meiotic sister-chromatid recombination aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_771931</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07098">
        <property type="entry name" value="ALDH_F15-22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="99"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4479444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="627" mass="70511" checksum="17474C6B9C3DAE58" modified="2025-10-08" version="1">MNKILYFILHPFLSFNLWSDEHREDEGIDVFYALFLCVVAGIWLVVQRERRSKNSPIPFHFSTPKEADPNWSSVKIEGPTLESHLEDGNIRPMMLPDRRYITCFDPSNGLHISTILADNEAEIAAKIQKALTAQKEWMYTDFVQRRRVIRSLKKWMVENQNLCARVACRDTGKTLIDAALGEILVTCCKMEWLIDHGEEALRPESRKSNFIQFYKKSEVHYDPLGVVAAIVSWNYPLHNAWSPILASIFAGNGVVLKCSENVIWSTSWFVNIIKNSLEACGHNPELVQLICCWPEQAAALTKSPYIKHITFIGSETVGRQIAIDATEHLTPVTLELGGKDPAVILPNTDLKQWISTWMRGIFQNSGQNCIGIEKLIVHVDQYDDLYDMLKERIEKLRCGSVTLPSDQGYLSPVDVGAMISDNRFDALEALIKQAEEDGAKIVNGERYHHVYHDQGTYFLPTLVGLTKNSAAIAQQELFAPIALVMGYETVEEAVDLANGTRYGLGASVFGPDQKQCLEVAEALDCGMVAVNDFAVFYVNLPFGGTKASGYGRFGGPEGLRSLTNPKVIVYDWWPGLIQTSIPKVLDYPIRSLGTSFEFTSGLIRFFYADTWRARIQGLITLIQAQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8W6</accession>
    <name>A0ABQ8V8W6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_922380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="16"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4480788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="528" mass="58895" checksum="1D3A77A66DA7D504" modified="2025-10-08" version="1">MAHLHDELTATSVRLAVDTRYGKVIGGRASNGAAVFLEIPYALPPVRFADAVPLPDDHKYPSGKEYLTESSYGFQPRNDGQASGTPFVDKVGYGKPTENPLFLNIISPPSFKPKSSAQAFPIKIYIHGGFLQFGSPHGVRGQDQFVSAELSEVRVNIGYRLSAFGFLASDEPRLDGNYGFKDQWLALEWVKKNISVFGGNPQDITVVGLSAGAHSVHQILHHVSRLPEAADSPFQSAILMSNAIVMVPKTPAELRPQFEALCYALDLDPKSPNILKTLQDPSLVPASKICELIETDALGTEYGTFRGCVDNISWMASSPDLMTWQRSGAFATNLTKKGVKSIVIGDLTEEWYLYSIAHPIPTPADIIVNLERYYPVEIVERMMRMYRTLGEDAGEGECTRLFGEILSDWQVHLPVRVLARDLHRAGFPVLKYEIAWTPEQLRPEGGYVTHGGDSYLWHLRIPDLEADQVRVAKDWLKKVNTEIMDLEHSSRSVQEVLKLGEDKDITWSTDDLWNEKMRLVKILQGETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V900</accession>
    <name>A0ABQ8V900_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="442" mass="48328" checksum="F27261BD53744D2E" modified="2025-10-08" version="1">MSTNYGYLPGCINTPAFVTRSKPGGVYDKITTGFAGMGSNAIANAELNQDFFRFNFGQAWSSNYSFRGIDSKQYTGNVFGEIVGQAHGTHIGAQGNHFVGNDLSKPKLLDDYTKTKCTIVLGCPSFATPAISDLFYNQICTLSSVRDADKEEEIRSDSMVIPKEMVKSLKPGGELDGIILTGPPLYTVLKRNTNADSSSSSLPNSPTKRNLKKRNWSASNDNETQEHEDIQPVEGAPTTLTLPSAQQIYAGAEYDHQLMPDFGGPVFAMRQAKLIQPQWTNINNDLIVPWEYYKHLRPGTVIVATICIEVFVMPTGPGNGAMRKIYHASITSLKVIAESDVVVLPPTPFITNKMPDRLPELSSSAATALATIDWSTSPTPPSTSGSDHTLEDANDSLESDVREGSERPTELKVVLDGSGRSVHLENDRIEHATENRKKKPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V909</accession>
    <name>A0ABQ8V909_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_489087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632055" evidence="1">
        <location>
            <begin position="21"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="198" mass="20615" checksum="8FF24CEF46432593" modified="2025-10-08" version="1">MFASVRLLAVMLASTSFVATTPVQISARSSVTTLANNFTLAALNNTLPNANSTGAPLVLGSAGAIDGESFHVSSTYASYPYNDFPSLGLVGGELRAFYPDGTWETNASAPLSGDTLDWGTSSFYSTPASTAFSAVSDGTFPILAVNEIADLWYLCPSDAPRVPQNSLYFNTTTIPSQSGVSAASPVVCYSVTLNMVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V933</accession>
    <name>A0ABQ8V933_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_841747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61562" checksum="4FFD8E72FD648BDB" modified="2025-10-08" version="1">MTRPNGSRKKDLGPSFSRAPSSIVTARHSTKKSRRKKVFYTIWSKIEHRLSEAYPDAAHSSSVLQGQKCKSFSPHSSIPVRSYLQRKASSHDSYQLSSYSCCLCGNHLKTPEHVLMQCHRASQIHIGLRQSFRTSALPYILKPSPHIQTEQQIWASDGSMIPASAGLLDKRSVTTSLTGPTTLVAQVSGISAFITHGELAGITAALILAKDSNNSIAVLHTDSLYCVRTIREGLAQSDPGAMANIRRYNGRSFYRWINDILHRKSTDIQHVKAHTEDTSLPSLLNSEADHYATSAQKLVHRIPSFPIPTFHMDEFTPYSSSHGWTESNLRVYTETVMLEKSLHELRNNVRMAKWLYEPRPPSEFPYTRAYSAYSAAIQLYARSGQLAVADTLFSRGKIDEPYCRFGCRALEDPHHLFVECKRYTEWRVETSKEIENRTQRKLTEKGFEETSQTSLLQTAKSLFINDKDIWPLQYSFYYLGHIPKLDSLLPYSPTMTPIAREQLLHHLAADWHTHIIRLAGRIFGDYQREMAKRLTSNHKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V954</accession>
    <name>A0ABQ8V954_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="490" mass="55040" checksum="ECF312A51F001366" modified="2025-10-08" version="1">MGKDTSPSWPIPSPYTRYSHLRNAAPKSVSSRTSLPVDYNADLPLTDAYASTDPDVEACHLYRDQAHFNFAAQKRLPTFDIQAGEYVPWTCQWLGIDRMIVALNTNQCTPAYCHHIINPSRSPEWCRLFPVKRNFKDPALDVVGYLTPRTHTCIWHPIHPSQDRLGFGGEFPGEDGAQTDTDTDCRVSSPVAPSSSSSNLSDHRVFASSTATFNTDQMVYLQRDLYRACDLDEAVENDHWVSLGPLFTSSHLRRTLETPDYKGTSLFTENEAYERQLTDREIVQSLLDAAESGHYLNNPRSHPAFDLSERGAAPACLHPFMDESSERIAFHRTGHLRGTPVGTALLLFNGTKGISIEEFAELRKRSHKCTSCYCYFSFDGYQRHIGYRGVCENSPDLETVPDLSTVLAKIKPFSIQPTFVSRPAATNAVGLAWLTWNSHIGVTHDTWAQLITAWRRCDHCGNVRSFQGHISHLEEKTDKFWSCGDGGDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9D0</accession>
    <name>A0ABQ8V9D0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_473229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4481840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="283" mass="31914" checksum="FEE93650005BBCA5" modified="2025-10-08" version="1">MIGGLFPVGVSDQVDQLLNDAQGGQGTVLDVGCGSAIWATNMAKIFSRAWVVGLDLNAQEFSDAPENFEFIQGDLDQTLPKFNGRASIVHCRCVAQHVRDPQTLVLMLSQTLRPGGLLLLADGDWTVYDQHKKLVEPFKWWNHGITNSNPAEPIVLEKDACGRSWYASWLDFFGNLTRSKDYRPIEELVKNVDTLTVLDSHRYLSPINWPGEGIENGEDLGRILNINQRDFFVGAKEIALQAGFSHEMVEVWGRHYEAEIDSGHFYNLWHYLTAQKRETPINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAF8</accession>
    <name>A0ABQ8VAF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_845083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="46879" checksum="DBBD1DA4054E946E" modified="2025-10-08" version="1">MTAKRLSRFFPWISPSSFKATGNESLVESAPPLRALAAVVDATPSAKTWKDLPNFDDLPMFKNMKGCAWEVWGKDDQLGTINLLTDEVVKKAAAEEIMYNCFVELVSRNSSSFKPGSVHHNSCVASKRPFHRPLQFPSKPLFGRKSPEVNMILKSPRVVRDDEIHINTQSGTQWDGLRHFGLQEHGVFYNNTPQDAMESGIVPIHDPLAIDPALAHIGIQNWANHGICGRGVLLDIVRYYSGELDGTGSPGLTELPYDPWTTHGLTVAELEACAEKQGVKFRQGDILILRVGFIRKYQNATQEARDALAARPETFAGIEQSEDMKRFLWNNHFAAIASDQPALERWPTGEGTPHMHQTLLGLWGMPIGEMFDVEQLSQVCAKMGRYTFFFSSWPLAIIGGCASPPNAAVRFVDLPSFRVNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB36</accession>
    <name>A0ABQ8VB36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eukaryotic mitochondrial regulator protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_772836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021036">
        <property type="entry name" value="Ribosomal_mS45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12298">
        <property type="entry name" value="Bot1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="337" mass="38105" checksum="BFDDC2FCB6804600" modified="2025-10-08" version="1">MSSALLRLFRTTQPRIWSQSRPCLQRSICYSPPALTDLSPEPPSLSEIEHEEELAAREEELAEAMEKEAESAPTPTEDQSAAPSDTSFKLFMKDTAPKFKFAAPNNWLGGNPFPLNRSFVPPPPISDKQRSEMYSLYMLDPEKYSVRALSQKFHVSLDRVDAILRLKGMESAWVKGNTLQTGFVTGMERILGMETNEATFVLRHDVHEADMMEEAEKNDPARQRYQRMYWESLPEFAGEATVPASLERSRRTAERLAAKAAQAKARKYLPVIPDTDTIQTPKALVQVSSKAGRPDIHFIDVGTKFLDITSETKRLAHIETRARLRAKKVAQKQRLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBT8</accession>
    <name>A0ABQ8VBT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_418929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046379753" evidence="1">
        <location>
            <begin position="34"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="117" mass="13469" checksum="E8FC5D55C90FC973" modified="2025-10-08" version="1">MLFRLLPSSSSLSGYLRLPLMFALLCESALVVAAPLLSTSPSSTAQTTYKMGIILGFYDSRMKDWERQPNQAEHKSFFTCIRSSGSFFAVDPKEQSRYQYHNLRQFFVRLGRTWQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBU4</accession>
    <name>A0ABQ8VBU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_539105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000071">
        <property type="protein sequence ID" value="KAJ4476306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045240365" evidence="1">
        <location>
            <begin position="19"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="167" mass="19091" checksum="827EE1F7A82239FE" modified="2025-10-08" version="1">MHFDPVYFVLGLLSMVYAVPVDLGSDLERSSFETTIRARMDQNPPQHSNTLPMELDKKVVHVRFTDPYAGRDLLQSHSQNPPKSVAAFVHVGLEKVFPEMRGDPDWLVTFENEFVGKFSISNLELTLWVHGIGDCEYAWCKVNIVYRDKIKDGQKIQTKKVTAKHIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBY4</accession>
    <name>A0ABQ8VBY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aryl-alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_838030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4486863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="43459" checksum="309AB215B9B66B4B" modified="2025-10-08" version="1">MSSIFQPEPPPGPHQKLARYRQLSSRSSVHVSPLCLGGMSIGDQWSEMFGSMDKQSSFQLLDTYYDAGGNWIDTANIYQEGSSEEFIGEWMEQRDIRSQMIIATKYTNIPGRPRGVPLAKQKVNFVGNNLKSMRVSLDISLKRLRTDYVDIFYVHAWDMHTSVEEIMDGLHNLVAAGKILYLGISNAPAWLVVKANDYARSTGKTPFVVYQAPYSILKRDIEREILPMCQHEGIALTLYFVLAAGHIRTTAEEEQRRTSGEQGRQGFFFGSWERTPDEVKVCDGLEKLAAEIGVKNISALAIAYVLHKAPYMFPIIGGRKVEHLHSNLEALEISLSKEQMNYLDDLKAFDKGYPSDALGDPSGYPRPVKTIATIDAIPVASVIRPVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCK4</accession>
    <name>A0ABQ8VCK4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_841157</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF12">
        <property type="entry name" value="MOZ PROTEIN REPRESENTS A CHROMATIN-ASSOCIATED ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4482695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="38087" checksum="9B57098A123475BB" modified="2025-10-08" version="1">MIIRQFPRWSRRLHTRAHLPPHSMSLIAISHRDTHTTSSVGDPHLPQSISMAHPLDPSNADAQQPTHTTNVVPNDETPSAPSSSMPSPGSPPSPPPPPAISKSMPEFERSNSSNLPSTVQRHEVYTPAYSHPPFHTHAFFKVLEGTFPTSIARSLMRATRALLVDRIGKVRREGLTHKDLDNQAYLFRAALSELRSGMTLNTKNDSATVQSATTALRREVDRLDVKMKEDITTLKHEIQIDLDNRKNEVKDEFARKDIIIEELLNKSIVSISDLRTDVEEVKWDNMRRAVGGLFTFATAVVIGMELRPKPPPPSPPVVPTPITRADLAPTTADALEKMEWVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDJ2</accession>
    <name>A0ABQ8VDJ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ThrRS/AlaRS common domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_885783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051335">
        <property type="entry name" value="Alanyl-tRNA_Editing_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462:SF1">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN AARSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4482727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="54584" checksum="097824474498FB6D" modified="2025-10-08" version="1">MGTVVRSPPSTPAEYFRIVSPTLRIPSPGTGISVPLGILACQRDPFLKKIETIVIACTVSQPPSTPAGKKTKKAVSAPTLPNEPILEVILHDTVIFPEGGGQPTDTGVITTSDGKTWSVLQAKRNGGHAVHYVMVKEGDLESALSVFTPGSTVTAALGQDDYDRRYDHMSMHTSQHLLSALLETRLNLPTLSWSLTNAPSPCYIEVPRGMTVEEIRLIQSEANRLVFEGRQVHTEVEELDRDKKATPVVIGGRSVGKGLPSDYTGGVNRVVVIDGVDRNPCCGTHLPTIHNLQLFLLPHTDTMSRSNTTSARLYFLSGPRLINYLTSAHDLLTSTASILSCGAPLVPERVSQVVDERKKSEKRVTDLELELAKRISTELSSEATVGSGNDGYIFRKHLHRTDDGGNVLGFLSAISVAFSEQMAHSQIPYLLLFTSTPSAQITGSTTVVMVVGSDDKEVKTIGEYLKSQLGVKGGGKGLKWSGKYTGVWKEKNEGERVNHVLKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE59</accession>
    <name>A0ABQ8VE59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_766749</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the polysaccharide monooxygenase AA14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054497">
        <property type="entry name" value="LPMO_AA14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22810">
        <property type="entry name" value="LPMO_AA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4489857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="341" mass="37237" checksum="CF8F44B6CCA8DF4D" modified="2025-10-08" version="1" fragment="single">ALFHPSMWGFNVTEQTFPYDNRPVAPLTNYTFDEWWFHGHLDFPPHPSDVFQLPAGGAATTEISCDKGATSFFASSPGGDVRQGDNVCPNQPIAEFHTTGFDDLKGCALAIAYKSNASEVVPEDFTVFSVNQTCVWTRFTDFQVPERMPECPNGMCTCAWFWIHSADSGGEQNYMTSFQCNITGATSTVPLAKPQVPRRCGADPEFGKELASLSNCTYGAKQPLYWFQAENNTMFEGAHAPPFYTDLYNFVDGPQNDIFEDSYLQIPNPSPVAAFPVLNQTVSVGVNVPFASAGSNSSTIDPSSESNTNSGSTDLEAGAWCVSAPFLVHLNKSLTVQSQYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEF3</accession>
    <name>A0ABQ8VEF3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CxC5 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_372390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4491660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="33003" checksum="210D8DDE99E017B0" modified="2025-10-08" version="1">MRARYELLSENYRQICSKSDCREPYPALGDILTAKVFETLIWDTPIEKVIHFPAKLSEHLPRIIDKWRSAKIQELLKLVQKSKQSKTLPVVSDLHLATTIFECTECTTAMHYPQMFYHDCCLQHKSPNKISHERMEMFRTNYFDFLGYGPWMIHTLVLSDQWPLVMEKLLKACSLDPTTTTVHELRSVNPPIECVTCSSTSRKTVCLWWRHAFSGKHQSHKLKFNTSSKYKEATTRALHTSGQMDNHICCAHCNREVRKSQFKNHLESGQSQRYFRRFDCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEH3</accession>
    <name>A0ABQ8VEH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_733948</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="entry name" value="Urease accessory protein UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4484543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="307" mass="33344" checksum="7FF579500B16A062" modified="2025-10-08" version="1" fragment="single">DDNDQTYLLLLLSDSNLPTGSFVASSGFESYIKHGFGGARDDDDVVVDRTTSFMSDSISAYARSALPFVSDVHRVVRGVTTGESSNSERYLQKIQDLDDLYDVMTLNHVTKRASKSQGVALLTLYSKGFSESPYSSTSPSMSTSTSTSTSSTSTSSTSTSTSPSTLPSLVTNYKTLVRAKRAPGHLPICWGILTGVLGLSLERSLYLHIFLHARSLLSASVRLNEIGPYNAQQLLLHVSRGIIKTEVGRCMNLRTGVNLRTAVDLRTGNPHSEDPGYPHSEGPANTWPLGEILAARHDLQHSRIFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEW2</accession>
    <name>A0ABQ8VEW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_765829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="79" mass="9411" checksum="49AEE5C7773ECAC6" modified="2025-10-08" version="1" fragment="single">RTQAQNLVRDLTWLDTSFHERWRRTIFTPTAPVSGRWKAFMRFLFAVSFFLCCMVVWVGLGGAYRAYRHKLVWGKRLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF01</accession>
    <name>A0ABQ8VF01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_981365</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="360"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="191"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4491871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1145" mass="131011" checksum="C022DE8298B7F323" modified="2025-10-08" version="1">MAEKPFERGFRRGRVEGKREALEILRRLGKLSEDEVKEYLQVLEEDEDVSPTANSIIPTPRTTESPVASPTKRLFERTFSHVEIPVASSSLKRKDPYVSFEHIGSSSKRIRQDYDEKEEEEEEEEEEEAYASNEESQAVKNRKRWKGKAKELDIDAGPSRLTPEHSTLRRKPLKSSNSRVFVEIPILTSSKKGRTSRDKVRSNWIASSSKHRGSNLTAFPSTSKRQPGYLTPTIPPSSARSSLEIDENDYDDEYSLESDTSIYFESDNHSRPNTSRSNTRVSSSEMISALTPNVHRIAKKFFRHEFEVIGPDLSSKEAVEREVTTNFTSHPGHPESMKWGKKLAVEENKIFFNTIILDGEEYEVGDVVMVEPGDDDRKGRQGNYKSKASQSSNGNANRFWFIQICYFFEDTDTHSKKFHGRWLEHGSKTFLQETAHSHSLFLTKDCDDAPASSIFRKCDVKFLQIHELEGEDDKNFQGDTYFCQYMWLDSEDPTFVSLPLQEEVDKDLEFSLDYRRCHSCVLNERRKEQESLRIKGNCISQFGVDYHTHEFIYIRPAESNDELLGIAQIISIPRTSNSAMLKVRMLKHMDTCHTTEESFADELLLEFDGPEVMIPFDRVDGKCFVACFPRQSVNGFAEWIKGKDHFYVVNSKNFKHCAPCMQEHERHLATYKDYLAQEGLLSMLELFSGAGGLGTGIEQSNFAKTVAAVEYDRNAAETYLMNHSDTAVFCKDVVELLRELENGDDIESLNRKPFPKPGDIDIIVGGPPCQAFSGANHNRKQDDIRATLPFVMLSYAERFLPKYFLLENVVGLLRHRLLGILEGRSILGGIQHGVFKLITRILLTLGYQVRVKVLQAANYGAPQSRERVIFWGARQGLKLPEFPIPTHAYAAKEHHLLQHADLKLSRSTRSRDPARPHFFAPFRAVTVNDAIGDLPAFDWINPHELIPATEQDEVRNIPRFQATHGRDLPGFLSGEYAHPPINYFQKFIREGMNEIVEEHVTPMFSPLIVERTINVPMKPGASLQDAPVQLHLEKKKLLPVIYLRLNPNQCFRTALTHCSPYVKNSYLLHYSQKRIITVREFSRCQGFPDWYTFLKAEYFKEDVRRAYKQIGNAVPVPLAFALGQSLSDALVVNWNRSQREMSPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFI9</accession>
    <name>A0ABQ8VFI9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_343004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021842">
        <property type="entry name" value="DUF3435"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF3">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11917">
        <property type="entry name" value="DUF3435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="655"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="970" mass="110979" checksum="8DEA421553AC87E9" modified="2025-10-08" version="1">MAAPSGITYKAKRSNREVLRERLQNNSALREHFESSRDVHHYKKLTRPTIHNHENVKGHYRDFAAYVQEIFEEGRSEKQPQPAEIVRGTPLPSIEYVKDFVCYLASALQGRDASTFIRLETLRGYMFTFLALWPRYANVHPTPEMRYQVCSYLLSEELQASVKLSTKVRTLKHIEPQCLQIIMETLHSATNIFRSNRTRLQMAFLILFSAASAARPGSIVESSCYRGSNQALTWGDVDFYLIPDDEDPAHPSLVIDIQLNLVKGYRDVDHRYQKLLFTLELRKEHRMTCIVLPLLGLAFHDSVFAHFHSIESLLCPEKPPTTRVKILLRNEVLTLPLLRKEEKGGGGKVSRTDAFHYDGLNRCLKLLSIAAGFPESITPYDFRASQGNKADVDLGETARKTLMLHDPNSKVYFASKFIPSLDLDAKYENRITLFRTVIAASSGRDTNAPHHLSLEERAKLLNEPELVKLQNEKDEAMNKIQQLLANEQSEEVEKQIIELRQIAAKASNGHRFLYLRESCLRIKQARQEYFDNAAVRQMLNPAEPVSRMSAGGSDDKKYRVESSFLSLVNDLDSGDPVTDCCTLVNILIAQPERILFQKFYPGERPDDENRCPHCSQELFTMSSTKPGEHVHLCTRRILSEKATAQIQANFTSQECKYGKCLEKFDQRSEFISHLMTHIKFARRNSNHCKWQIAPGVSCGAEDIKDWREHFAEIHGLNLDQCIFTEYCTICGVWLYDILGDRQVFSNHHLAHYQDLFDSFSSRPPEGASVSLSPIGIIETEKYIEYTPGSGFDGELPEFHGHFSDGIALVPAFCPSCVFDEKLPMYTRMHQFSNVFHFMEHFNNIHRPLFTESENLCPVPSCGHHHFTKQELVIHFIKFHRLPLASTGRHYKVKRLLLPSPDGEVVKYKRRKKSEGFWCIGCSGEVNDINKHLQRPQNSDKARECARIGKYSVIANGERGPVQFWTAPVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFJ4</accession>
    <name>A0ABQ8VFJ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_765718</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4491880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9283" checksum="BBA22F00EB56B4DC" modified="2025-10-08" version="1">MYLFLSSLFLYVGALAIYRLFFHPLSKYPGPLLASLTDWYEMYYNIIKGGALVTKINRLHKVHGPVIRIGPNTVSQTHSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFY1</accession>
    <name>A0ABQ8VFY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C8R41DRAFT_867209</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ4492522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="159" mass="17652" checksum="9EB07E826686CE07" modified="2025-10-08" version="1">MLSDLNVDLKIGNADAGSYFNDLVLESVDYGMANVHPWFANQSINDAAGWTWSFFETTDVALAQTLANQPDMSIAETGWPTNSTNVGNESDGPSVASEANLQIFLDTFVCQANANGTEYFFFEYFDETWKTEVYGGVEGYWGLFYSNRTLKNVEIPDCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG98</accession>
    <name>A0ABQ8VG98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_837049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31649">
        <property type="entry name" value="AGAP009604-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31649:SF1">
        <property type="entry name" value="FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00696">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4487512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="196" mass="21625" checksum="647196858EC2AFCD" modified="2025-10-08" version="1">MEFPQAHGQEPIMVKDQRSSPAYNINVAPPPIPSSGYRIPLAENSAFPTDLRPLFFDADGVSPVFMGSAIFPDSVHPCKIVPALDPKCMVPYGGREHHHHGRYDLLPLDSNTMEFVRTSRGQIPPGRRPVEGGYEENGSKLYHGIATVNGVQVPGKTGLHLGGCNVSFAGGEHVIYENYDILCWKFWLYESLTPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGE4</accession>
    <name>A0ABQ8VGE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="526" mass="58377" checksum="DBC4F75B4392C192" modified="2025-10-08" version="1">MYATIGLGAPWAVPGLSYAPVGQGLPRNDVELSREMLQIILEHLSTVIASEFSGIPIRLVAHGGACMLLHPGLYELANRKQMYHISRGENPSRRTTTRDVDYIHRSFVAESESRGIINAGERLKKCIQVTAQKFQLGADWMNSDADVALPMSIEDLMRSPNTGVPFDPIYAQSVKENNIHLYTVFTSSNQQLTIVNVTPFWAVALKLVRYTKWDPGDICLLLLYGSVTRKVQWNAQNLENWIRFNCSAMNYHNWDSLRIADMRRNIDHAVALISSVGSSIMAQPGDPLLPSQSDEKPFSKFGNTRTTANVKGLMHATKTIHSKSTSNVVMPSTGGVPWAGPASDTLPARSSDPELELENSSPRTSPAREGLIYDLGLKAPSRLVQSPSTEDRKRNARTRKSTDWIREHEEHMQRRSKYMLRSDEPDDSDETDTSNDTDIDEIGKSHGRAPVIPMDRRSKSVPSLLGATDQPMVSNQWGSAAASFSDHSWRTEGPSSMNSFETSALPSCPPPIPDRRTRPPVTTPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGG9</accession>
    <name>A0ABQ8VGG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Ceramide very long chain fatty acid hydroxylase</fullName>
            <ecNumber evidence="18">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C8R41DRAFT_764430</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="18">Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the sterol desaturase family. SCS7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="18"/>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014430">
        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863:SF1">
        <property type="entry name" value="FATTY ACID 2-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863">
        <property type="entry name" value="FATTY ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005149">
        <property type="entry name" value="IPC-B_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17 18" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="10 18" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="14 18" id="KW-0408">Iron</keyword>
    <keyword evidence="5 18" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16 18 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="20">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR005149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ4493340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="367" mass="42899" checksum="13FDE6E820318B2F" modified="2025-10-08" version="1">MSKRVRIFDVDELSAHTSSSSCWISYKGKVYDVTGFLQDHPGGDDVLLKYAGQDVEKVMKDKTEHEHSESAYDILDEYVLGRLGSTENIVRDDWEADDDFDPDATDAVEDLKKHHFLDLQQPLLPQLWYANFSKAYYLRQVHQPRHLSDSARLFGPEYLEVFTKAKWFVVPIFWLPITFYLFLRSALQFTTPLPPFMVDPTLPLSGIVNLPADSILKTLICFFIGNFIWTLLEYIFHRFLFHVDYYLPDKPIFLLIHFLLHGVHHYVPMDRLRLVMPPPLFAMLEWPMTRLAYKLFPLPVANGIISGAFALYVLYDCMHYALHHTRLPVYMNEMKKYHLAHHYKNFDLGFGVTSKIWDIVFNTVLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGH7</accession>
    <name>A0ABQ8VGH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_981005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047323538" evidence="1">
        <location>
            <begin position="31"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="228" mass="25786" checksum="C4EE5446C79A90F0" modified="2025-10-08" version="1">MFLRSISLSCASQSLFVLLWTSFLASAISATPLPSGDGMNKIEIRNAPDQFPSHESTHNTRMVYIPRAPTKYTVDVGYSIRNEGDRLEYWSLYFGKDILEATPGKDSRTWDPRTQALVPNHRDSDLEQMGDLGSSYQHHWLGKANFKNEPEALGIFQKLGSKEGSEIKMPPASTIGGLSLDYGRLVLEHLKKEGHIENDVMERYMKSYKVGYRRVSENRFGVVWDPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI36</accession>
    <name>A0ABQ8VI36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_345641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="359" mass="38767" checksum="B0667BC00CC1C658" modified="2025-10-08" version="1">MWHSTSSLISSFRKSTLLKRKGEEFALRREKAQRKIESEKSKRLAEVLKHQAEVRAAAEREAARLLEIEAEEKAAREREEQTRLEKEREEREQREKEEEEQRQKEERERQQREKEEKEKEERRKEREKERQKTTEQARLQREREEEAEKRRSQRALERAQEKEQGSQRKSVFGPSGGAPAAGDGVSPGAAPGAGVWRRRAAAETTPSGTPTSSVPGTPTKSAFGTPRASAAADIPARSESPAPGAGAKYRPGGGLGGGLGGGLGGGRSDGWRSRLEAKGKGEAPPPSTGTEGVSNGRGGGTGSNVPSRTGSPAPGAFGGRNDAKGGEKGEAEDGFTVVGGDKKNVWKPKRGGFGGLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VID0</accession>
    <name>A0ABQ8VID0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_724874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="96" mass="11005" checksum="9B9C2E3480AC1B36" modified="2025-10-08" version="1" fragment="single">LRDIRDSPVFKEIPGPDGKPFMQLDENSHDLPVMFSLGYDAFHPFHFSNEKSHISSTAIYMVNLCLPEHLRYKKGYMALVTVFNGDPNVNDINHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIH8</accession>
    <name>A0ABQ8VIH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_310000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047285691" evidence="2">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4494268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="152" mass="14933" checksum="0CBCC44A1A5B73C0" modified="2025-10-08" version="1">MSAFSRLFAFALLFISLLLVEDTVNALPLDGRTPNDVASGASGPSRGGDVVHAPNSNENCANGDCGLGATPLLTIFSHNGGDAGSSKSGYVSGSRATTKQCKRTDGANHFSGASGDASGGSVPDGDGMVDLMSDNGGAGSNSASGDSNNGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VII1</accession>
    <name>A0ABQ8VII1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_836096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="173"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="321" mass="35351" checksum="01BAE13EDD181E02" modified="2025-10-08" version="1">MPATIQSPGEHQPLDNTMGAMLVGIIVSAVLYGISLVQTLFYFNRYRDDAWYLKSLVAITVLFDTVHLCFVSHTIYFYLVSRYYDNGQLDFMIWSVLAEAIPTGFTGALVQTFYTVRVWRLSKKNHVLAVVIMLIVLAQTACGTAWVIISLQLSTFQQLLGISDLTISINALSTAADVIIAASLCFLLAQSRTGFKHSDTMINKLILFGVNTGLATSVCAIASLLSLIASPKTLLYAPFYFCIGRLYSNSLLATLNARNQIRNGSNDAEHMMVSLSQASRDHAVLPTNSKTQRPQNISIRIDTAKDYASDGKEDESSSVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIS0</accession>
    <name>A0ABQ8VIS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_390968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="23365" checksum="71422D5C3D1C6688" modified="2025-10-08" version="1">MMFGPGLNSRVLAPFVKSIVGVDISQEMVDRYNKRVENQGIPREEMRAICIPEQLLTHVNDLRLAKLLGDIEFDVAICCMSYHHFPSIYSITRTLSSLLKPGGHLYIADVESIPIKATPHGPDDNNKQSASDLEAIFPDGACDAGVVTHKYGFSELEMKNVFVQAGLADIDAASETGQIGSRFTYSIATRAFKKGKAVNIFLARGVKPQKPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJE4</accession>
    <name>A0ABQ8VJE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_828402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="247" mass="26747" checksum="497F3751C0E18673" modified="2025-10-08" version="1">MAKLVKKSNTDSGMPAKLSIKGNSPATSMYLSTRNVATPRPTTVSSSKEPGKRISNTMQIALASATSSSVSYLSSTPALNPAPSLDLNKSTKTKSMNLYPQSKSVHYWAARALTAETLLAAGMEHSENLRSVTVSQETKRATEVAQLTKLYDKRLAKLEKLLVTLLGVLFTITFLTFFSQLTLIHGGRKDTSTRSQWAHFTIPILSPFASVVEHEVSVVGSKTIVGLGLVISGLAYLLLRHDGRNRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK61</accession>
    <name>A0ABQ8VK61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1349-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_829183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="21879" checksum="43CAE83F5C60B195" modified="2025-10-08" version="1">MTSTFTITAPPSTDIWRKPPSTNSFNAPTYALLPDAIPLKAFHRARITFSGVWTTRYDQGGLLLHLTRAGSTDRWLKTGVEFYQDKVYLSTVSTLTYSDWSITPPTTGDNVKSTTIEVRREVDELGSSLWVYELVLGDSGEVLERQPLREVTWFLAEEDGWEVSVSAMAARPAKKESVVGTKELAVKFEGAEVDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKB9</accession>
    <name>A0ABQ8VKB9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="189" mass="20921" checksum="D4F5BD5A8A922E3D" modified="2025-10-08" version="1">MSTPSPAVESTSRVVAPPMSTPPSPSHPPIATGENDIDELASTIEDPPLGHLTLFKSSRFLAFLEIHGDPGQRTRFSLLPEQWRTIAGKIESSTSSTQALLELSPLDDQDRLEEDRLELQDFIRRQPQLPTVVEPVPSGSRPPVVQDKVLSIPKKRKRNVRMGETASSKHGESFRGYGAPHPESWERSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKE5</accession>
    <name>A0ABQ8VKE5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Fet3 ferroxidase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_304002</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13851">
        <property type="entry name" value="CuRO_1_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13899">
        <property type="entry name" value="CuRO_3_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045160658" evidence="9">
        <location>
            <begin position="20"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="12">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="154"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="409"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4494422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="631" mass="68289" checksum="11046BC99F965254" modified="2025-10-08" version="1">MQPASVFLLLTSLVSPALAGVQELWWNITYVEDANPDGLADRRVIGVNNTWPPPPIDVNSTDSLIVHMTNSLDALTSLHHHGMFFNKSSFMDGAVGVSECGTPPGGTFDYVVPINSSGQWGTYWVHSHAGGQYVDGLRAPLVLHPPTEVHSYDEEFTIILGDWYHTEHNVLLQQFINIANPGGAEPIPDSALIYLAQNASYLGPISGTSPSPVTSAVGFNENSTLPFQPGKTYRLRIINTSAFSMFYFWIDGHDMRIIEVDGTDTEEYPISLISLAVAQRYSILVTARNDTSSNWAIHANFDTDMFDTVPDTLQPNITSSITYSSSASITDSGPVDAYFAVDDTQLVPIQQIAAPDATKTIQLVAAFDTMDDGTNHAMFNEITYNSPLVPAILSEMTLGSNATIEEAYGPLSFVVDHLDVVDIVIQNSDTGDHPFHLHGHKSMIVGRATDYTSDDPTLNPPIAANQTNPVRRDTVLIPAGGSATLRVVADNPGVWFLHCHIEWHLEVGLAIQLVEAPLQAQQYADTVPQALSDHCEALGKPASGNAAGIASATDLTGLPLGPFPQNNGWHPKGILAMFGCVLTAVIGMLTVAWYSIMGGQISEEETEHEVREAIDKKAKRGKFFGLIKPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLE1</accession>
    <name>A0ABQ8VLE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA protein C-terminal winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_234453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056808">
        <property type="entry name" value="HTH_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36168">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36168:SF1">
        <property type="entry name" value="ORC1-LIKE AAA ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24913">
        <property type="entry name" value="WHD_AAA_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA protein C-terminal winged helix" evidence="2">
        <location>
            <begin position="424"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="585" mass="66432" checksum="E9F7C6F5B2793723" modified="2025-10-08" version="1">MLSISRVASRLQWPTLRSRTFQTSLRYYSESSQPSSAPGEKERTRPAQSTIHPAQNLPLAKHEVQERSEAINIPFNPPGGGGGPGPGGSGGSFQFTGSPFFDATLTTLVGLGVVFVGGVAYLRWYKKNVLDKIELAFEPGYDPALEVARHYDTTHKDAALGLEDPDSVPWTEHLRRREQDRIDRMVKGEEVGHYYVLLGPKGSGKGTMIYDSMSAIKADGVAMCDAHPDLEVFRLRLGKALNYEYNEDSQTGLFQRRDPREGGAALDIERALNKLEKVALRCARRRHKPLVLIINNVHYFNNDEAGRNMLLQLQQRAEAWAASGIMTMIFSTDDFWPFHVMRKVASRMHVLSISDLDTREALHACTRMRANVKNKIEHHDHDQIKEAVSIVGGRLSYLNKVASSKDVLEMSNSLLEIEKAWLLSQIGLIQDCDDDVMDEQKWSSCSWLLLQEFVKMRQEQEKERDEGLQSLDQLPDLPMPSLPYYKCRQIMTRADFLEELDRVNIISIDMNHNVRPDSMLILLAARQVVEMENFEEVLNSVRDRIDEIESLHRTRELTFKDVDKGDRIRLVVDKGGAELLESKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLQ4</accession>
    <name>A0ABQ8VLQ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_822839</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IWS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051037">
        <property type="entry name" value="RNAPII_TF_IWS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010:SF1">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="5">
        <location>
            <begin position="202"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00037992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="388" mass="43784" checksum="D5B77582DCDEE1E4" modified="2025-10-08" version="1">MSTDKLARDIFGGSDSELSSDDDEVQDRQLDTTAYDDNDGGSGADSEDEYQEKQPSTTSRKTKKTGKLKQRAEGEEGKTRKRKRTSTVKKTKKSAYEDVDLSQLPPEQANKIRLDRQIEAILKTKKSSRPKKRKNNDEVLDSFADDEVARLRETMNNAAEEDMKANQEKLPATAKLRFLAEAMETLRKASLAQSIIDNNLLDAVKRWLEPLPDRSLPALNIQRELFVTLRKMEFIDSSVIKESGLGPLVLFYTKCQRVQPDVKRVANELVSIWSRPIIKRSASYRDRVVPTMNNMDVDDGPPGSQSLTQSQYRPEKLNAILARAREEDKNRIRKNAVSIPQSSLGTYTVAPKNNAGLAKMNASVDNDVERRKKNAERLRSLTRKVAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN85</accession>
    <name>A0ABQ8VN85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3 8">4.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_758585</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>orotidine 5'-phosphate + H(+) = UMP + CO2</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3 8"/>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278:SF9">
        <property type="entry name" value="URIDINE 5'-MONOPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="9">
        <location>
            <begin position="34"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4497854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="30160" checksum="67024ADF44D561B6" modified="2025-10-08" version="1">MASFLRQTYGQRIQNHTNPAAKLLLETMERKKSNLAVSVDVTKSKDFLAIIDAVGPFVCLTHVDIIEDFDQSLVQQLQDLSIKHDFVIFEDRKFADIGNTVALQYSSGVHKIANWSHITNAHPVPGPSIISGLSSVGLPLGRGLLLLSEMSTKGALAVGSYTQEAVRMARAHRDFVIGFIAQRTMEGIGMQENTVNKDDFLILTPGVGLDAKGDAMGQQYRTPRQVILESGCDVIIVGRGIYGKDPGLVDEIRAQAKRYMEAGWEAYQDRVSAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNN5</accession>
    <name>A0ABQ8VNN5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Superoxide dismutase</fullName>
            <ecNumber evidence="2 7">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_895292</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 7"/>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF6">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="8">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="9">
        <location>
            <begin position="94"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4495442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="22255" checksum="DC434AF3BEFB3609" modified="2025-10-08" version="1">MSNTLPPLPYAYNALEPFISEEIMTLHHTKHHQTYVNALNAAEAAFAQASTTKERIALQAALKFNGGGHINHSLFWQNLAAPSEKGGSGGVLKDGPLKEAVIASFGSLENLQKEFNTTTAGIQGSGWGWLGVNPSTKRLEIATTANQDPLLTHIPVIGVDIWEHAFYLQYKNVKVEYLNAIWHVINFDEAQKRFVDATSGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP47</accession>
    <name>A0ABQ8VP47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation initiation factor eIF 4e-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_234011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0696 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015034">
        <property type="entry name" value="Bles03"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977:SF1">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08939">
        <property type="entry name" value="Bles03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="353" mass="39957" checksum="2B58262999B0B7EF" modified="2025-10-08" version="1">MTKANEDAIPEGDYKYAWTPTSNVPLDDFLSKYKPSMVENDGTKPWIWVEKGGDTRSFTPADEIAVLEESSKILTEITDQIENIKNDPSIPTRSNKKTGAKSKKEVREELQRDARERFEQIARKYNYLCGKWLMFASTEKIDMIWSSLATSLINGPLADTDAFCAKVATTPRDANPNHLHVICLYFPDVYNKDAVTKAMKILLRNHGFNLSGVKSDMYTLLGIDSKHPSGIPSTIWKNKDLMDDKEIQALKDAFFAELKGGKSSIAQSPDKADPNDKKAMDVSAADKPKTKRKQKDIFASDDDDDDDDDDEHKRRAELMQKKKATAVSKRRIDKDKDSDKDQEKPKRKAARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP48</accession>
    <name>A0ABQ8VP48_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_819530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PRA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18252" checksum="44D1A2E7422A0AF9" modified="2025-10-08" version="1">MEAVMRVTDTIKSFRETRLAALRPPTEFFDYQRISRPSDFNQATQRITYNTRYFSGNYVLIIALLAVYALISNPLLLIALGFLVGGFIAINKFGPEPMQMGEHTITQKHLYTALFVIGLPLLFIASPVMTFFWLVGASGVLILGHASFIEPGVESEYAAVQDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP62</accession>
    <name>A0ABQ8VP62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="291" mass="31467" checksum="4CB5A54E30C85C5F" modified="2025-10-08" version="1">MSLASLESILSVKPHQPELEPDLSEPDPAINYDHSRDAYREFLYIQIRDACKLSLTRAPAKKREYYLSRAAMRAFVGWAGFTDIKPLPQVSNYAGFLRMRNPLELPPVPTSNPTTVGPLSTPSEKVEVQADPTNTVASDLPISTASDAFKEVTPMPSAEPVVDPTVTPASDPSPLPISTVSSATPTPIPTPAPPQLANSPEAIAQLRMANSILKKIHKPKKAKTQVHSQSHTNRNLTPGVPPQKSQRPQKDATPSAQSGEHPVSVEVNGKAADTSKNNATSKLRGFMGNWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPL2</accession>
    <name>A0ABQ8VPL2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sacsin/Nov domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_148393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022155">
        <property type="entry name" value="DUF3684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12449">
        <property type="entry name" value="DUF3684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacsin/Nov" evidence="2">
        <location>
            <begin position="25"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1398"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1488"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1398"/>
            <end position="1413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1701" mass="189691" checksum="2618C75D28B6EF4B" modified="2025-10-08" version="1">MAIQARNQLWATGHDETVEVNQRALIDKVLARYSGEFTVFRELLQNSDDAQSKEVEIRFETRGFLEDKVEEESPAPTRLPNLKSALVHQWTFKNDGITFREEDWNRLKKIAEGNPDEEKIGAFGVGFYSLFSVTEEPFVTSGGEWMGFHWKRDQLLARRGKLLDTAEPSKWTSFEMSLREDTPIPAAFDFTRFLASSITFMNHLSTISVYFDDKRLTRLTKSTGIPKELGLPKTLNVLNKSKMMTLDKLKSTSLLIQADVMRWVYTSGSEKAPAPSAIKPVKPPAPGGFFASLFSGLTSTSTTPHPPVTTTETSKPIDPLKTDTTSVSLTVFSADADVKVDQKLAAELHRSTKKSVPKKIKYELIYTGMDEYKASKAEDEQQTFATSGSIFQGLRADLDGMGSARIFIGHATSQTTGIGGHMSARFLPTVERENLDLMDRNVAIWNKELLSIGGTVSRAVYELEMDNIKHMSDSAGPAKSPELQTWLMDRAVHVLKFFTFHQSTPSADVSSLMEQAFFACSTGFRIISTNGIQDVADIRLPDAQFSSFLKDLPVLPEQLLTAARPMVTALQNRKLVKAITFNDVLKELRNRPLTEDESVACLTWWISLNKDGESAARLHSIQKQLLDAAVFTTGATGSKEERIIPLNTIQTILNPRNMAGNIPLDAPFPPTMLPPSFSKSFKSDQLTFAFHWTELTLVEWLRFIATSGPSPEYDLSVSTLWSERVLGILARAWPSLSSHMKDEIVQVLKSSACIPTSHGPKIPEETYFANADIFHDLPVVKLPSGSAVKGNLERVLIALGVRKHVELQIIFTRMIKTNEWTISDLIKYLVSVKDSLSAEEKARLKLTNAFSAESTPGTEKSNKRYRAEQLFEPSPIFTQLELPIIDWGTKFKWRSSSEEARFLFDLGLQRYPSLSTLIDLCASSKPQIRVVAFKYLLDNISTKYQDYDSQDFHSVKFIPATKNGSPYLSSPGEVLSGQEWEVLGLPVLANAALGVGPKLGLREHPTSAFIVSFLEATPPRDIPQATVMFNLMSNRISDLSSSQLQKLSQLSIVPTRQKKDNGIQIINIRPSQCFFGHEGKDGFHSKLFVFIDFGASANSFLSACGAKREPSVEEITLMLLADAHNFYQLAGGPNSFLDEIRNIAVNSRLLSNGTLARLKNAPVLLALQRRVLVEETSKKVVDGDEDWETQYDLKRPDQIVIADDSNSLQLFGDKLFVAPQEDMLEAFYILLGSKRLSALVQENYEVTNEINNSPQAAKLQAHILERLPLFLHEHTHARTKTSFTWLSSSNNFIVRSFGKISVVKSLKFGSVNLSKRQAASVVGPKSNRGPLQIWLANDVETDMYEVATSFNRLFFETPKANDALLFMTILSTDLQALKRRGYNVERIERKYREQRAEQRKAAEERQAVEDGKVKSLMSKPPTRVSTPTPIPGTPLPGAFHEMPQNTDIPIEHNPVPPSLGEKGLNSMGRPNSTLNPFHKFGRKLGFRGTEDSLDSSPGPSIPRNPIQGATPLGNITANIDMAIKACRPESGNLLRNREQMQQVKESLNEGYCDISGRAEDLQHAGTVGALKVYLSAEVPDKQTFLTDKSAPLQRFLGIVTSLARIYSLPLTSLHIFYDLTGPLIAFNRNASIFLNLRFYEAWHDSEVASGDLSTALVSWYFTLAHEIAHNLVQPHNSEHEFYFAAICERHVLQLGLEASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQG7</accession>
    <name>A0ABQ8VQG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_818326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="76" mass="8951" checksum="CEAF144492B15C07" modified="2025-10-08" version="1">MTIELSLLTHCFTCVLLMFTTSQGYWALLGWRVVYSYISCTLPYLLYFLSFDLVYSTWFSPELCLPPLSFCHLRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR15</accession>
    <name>A0ABQ8VR15_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_916276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="234" mass="25362" checksum="B0A563B65A5E8F2B" modified="2025-10-08" version="1">MPPKTQAQSRANSEENTFFTTAQSFAPFSESISAIGQPRRRNRGFGSATVPTTLTLPEAMEEDQQFEYSTLYTGDGQPVQVLTPCCGQPPMVALTRGRSISRQDSPILQAIARRTGKQPQRRATSNSPRDPPYLRNTKRRNGGPRHGLDTPPHFNLDAGDHDDQDPLVDPTNLGVENPENQELDDGSGSLPCGPHSPNSPISPDIPNEQCAMLELLSGFKGSIKTLGTILTTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR34</accession>
    <name>A0ABQ8VR34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_820135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11283">
        <property type="entry name" value="ADF_GMF-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011171">
        <property type="entry name" value="GMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249:SF2">
        <property type="entry name" value="GLIA MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249">
        <property type="entry name" value="GLIAL FACTOR NATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001788">
        <property type="entry name" value="GMF-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="2"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4497925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="140" mass="15583" checksum="70D44EA20B4090D1" modified="2025-10-08" version="1">MSHTVDIPQSIKDSLRKFRFARRNEGSAAIVIKINKQKLIMEEVEQFDNISIEELAEELPENSPRYVILSHALVHSDGRTSFPLVLINWAPTSSEIGLLTLHASALMDFQTTADVSKVIEIREGPEALTSDVVDAKLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR75</accession>
    <name>A0ABQ8VR75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_915934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35871:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35871">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="509" mass="57610" checksum="8D3BC30A950570F0" modified="2025-10-08" version="1">MALEALHHLQTVLRPAVSGKQKRCKDPKINSWSKTHLIEVKHMLNLFTTVGSHTYGKWQQSSVQASIALKKTHTTTSSPASQIHTRNCKVSVTNIQGPKVDSRNVNPYGAWAKSILETHPALKVEVMNHLLSVGKYVQAHDIVTFLNRDDVKGSADNVEEVVDEIIAAGRRIVVWFHNESIFYAHDRRKAQWVPDGASPEPYAKGEGLSLMVADFVSADYGWLWSKDGKESARVIFRPGKNRDGYFDNNDILAQTQKAMGILLRDYSDKDHVFIFDNATAHLKRAEDALSACKMPKFMPKEGMNWGVEVTMKASDGSIVYDEKGKPRKMKIRMCNGKFLDGRTQEFYFPKGHPRAGIFKGMAQILRERGYTDAHALRAECPKFKCDPLAEGRCCCRRLLFNEPDFATGLSLLEILCKERNFQCWGAAKRTYCLMPSSSKEEDLQHNMIASLDAIELIRMRGFARRSRRFMDAYHRGLSGKQAAWAGKMYHGHRVLPDSPMKDMEVANLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRB6</accession>
    <name>A0ABQ8VRB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tyrosyl-DNA phosphodiesterase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_893858</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
        <property type="entry name" value="PLDc_Tdp1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="55"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="613" mass="68890" checksum="60C2AF1A0FC0C5A2" modified="2025-10-08" version="1">MDENDNDLERAIALSLQDHTESSSGPITLNEDEALFQQQLQHAIEISKANVQRGELAQPSASTNTFLSERAQLEKERRERQKRLRKAQGLPDSDDDLRAVSDEEDLGQPNAKRQRLSSSSVSYIGQTNVRTSAVPSSSKLGPIQGSFFWDGEWRPTATLGVEPRKDGRSTFRLSEVLGEKSDISFAILSSFALDIPWIYSLFDPSSPVIMVTQPDSNGKASVKNALPNWIKTTPFLRGGYGCMHMKIFYKTGRLRVVVSTANLIPYDWRDIENAVWLQDLPPLPKEAPFNRQDNESFPSVMKRVLDAVNVMPALSTMLKQDHPNLPIKTTEQICTRWDWSNVKVNLVPSIAGKHEGWPNVILTGHVRLMKAVRNMGLRTGKGPKEKTLEMECQGSSIGSYTTQWINEFYHSAKGESAEDWLDKAKSRREKLPYPVEVKVLFPTLATVRSSQHGERGGGNLFFQRSYWEGKKFPRQLFYDSRSKAGKTLMHTKMIVGSISQKVATKGPQKEVINLDTDSEDSDSGEEIEVVDANVGWIYLGSHNFTPSAWGTLSGSAFNPIMNIRNYELGIVLPLKDMAEGDKLACFERPPRKYGPDDSPWIQEESIYFKPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRD8</accession>
    <name>A0ABQ8VRD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_817016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047323550" description="CFEM domain-containing protein" evidence="5">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="6">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="95" mass="9856" checksum="076FD0DFE20779B1" modified="2025-10-08" version="1">MAPSTSGALLLATLALTTILGRAQSNSTLPVCAESCAVVVGAEVACNVDDGSCCTNSDFIVDVEYCVNLDCTTTEQQEASSYFDSFCGGTQIWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRF0</accession>
    <name>A0ABQ8VRF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_756014</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07792">
        <property type="entry name" value="ASKHA_NBD_FGGY_GK1-3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042018">
        <property type="entry name" value="GK1-3_metazoan-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000756">
        <property type="entry name" value="PRK00047.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF69">
        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="12">
        <location>
            <begin position="285"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4498949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="541" mass="58664" checksum="75B0782F4D82DF98" modified="2025-10-08" version="1">MSLKKGEFVGSLDCGTTSVRFIIFDKYAQIVAQHQLEFPQYYPNPGWHEQNPLEIQAHAEACIEQTISSLVASGYTKDSVKVIGITNQRETAFVWSRKTGKPLCNAIVWDDSRTKNLVAHYEHVLQTKGIEVTPGVWKQGQEGIDALREISGLPLSTYFSATKVRWMIDNYPEVAQAHANDDMCFGTLESWLVYNLVGGVKQGLHVSEMSNAARTLLFNTTTLNWDPMLFKFFGLRQSIVGDVVSTSQTYGHIAVGPLAGVPIGGLVGDQQAALIGNKCLSKGEAKCTYGTGAFLLFCTGNEIVKSSHGLLSTVAFQPGPNSKPVFALEGSISSAGSAITWLKDSMRMISSSAQVNDLAAQEPTSGGVYFVTAFSGLLAPYWDSSATGLLIGITQYTNPSHIARATLEATAFQTRAIIESMVLDSGKDVANLKVDGGMTNGDLAMSILADLNGTEVIRPEMRESTALGSALLAGSAIGLFGWDLTKPESLSEVNTKGTRTFKPEMAASIREKKWTNWQRAVERSRGWEAGFDEEEEEDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTU3</accession>
    <name>A0ABQ8VTU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_608060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="23"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="382" mass="44332" checksum="5FE628CBAF68CE2D" modified="2025-10-08" version="1">MSDLERELERLRPSNFPVDGRALNDNELWWSGHFEYLKDHGYMMRPRYRPGWKPSFKPGVLAALASEDGQNMLHPYVMDALRISDSYMVAMKKVNVSTAEENIASFFSSKEHNTDSRNHCIRVLEVLPVPGNDDEKILVMPWLRDVMDPRFRTIGEAIQFFKEMIEGLQYMHENNVAHRDCARNNMGMDANSMYTRQYHPIEPKKRYNWSGRALHHSRTRCPPRYYFIDFGRSEMYDPKEPRPLEYALKSGGYTPPEGDADIPCDPFATDVYILGTMIRASLLDGEQGGMYVPRPGVHGFEFLRPLVNDMIADDPSNRPTMNEVASRFSTIVGKLRWWKLRSRAVQKDEFLTTPFRALYHIFWTASMMLLLKPAIPSPKDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUJ3</accession>
    <name>A0ABQ8VUJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_939888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF26">
        <property type="entry name" value="LD44506P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="73"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="369" mass="42761" checksum="67A716BF6FADC9C8" modified="2025-10-08" version="1">MFSSYRYVDPLCGIRRPAPISRGSKDAIATNPEKSDKLMRERSIRTNRKHKFVDCLSNQDVNIAELRKLAWAGIPNELRPMAWQLLLGYLPLASPLRAATLARKRNEYTSLVEVAFARDREGVDQQIWHQIEIDVPRTRPGVRLWMYGSTQRSLERILYVWAIRHPASGYVQGINDLVTPFFQVFLSAYIDSDPEEFDPALLPKSVFNAIEADSFWCLSRLLDGIQDNYIFAQPGIQRSVRRMADLVARIDAPLFSHLESQNVEFMQFAFRWMNCLLMREISVQNTIRMWDTYLAEGPDAFSQFHLYVCSAFLVKWSEKLRQMDFQGIIMFLQSLPTQGWGDHEVEMLLSEAFVLNSIWHNAQSHFNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUJ7</accession>
    <name>A0ABQ8VUJ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_863679</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="115"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41130" checksum="F9A2261ED152931B" modified="2025-10-08" version="1">MYWSRAPVYGACPTRTMRGHTVTLVDSTAWVFGGCDDKETARDIYCFDVETMQWSHPITNGDLPPPSRAHTATLVDRKIYVFGGGQAASYSDSVYVLDTVTRKWTKPIISGAIRDPNTGEVIGSAPGPPGSGGSNHGNGTNSRSSPISSTVYGEIPAPRRAHTAVYYNGKIWMFGGGNGMMALNDVWTLDVSKMIWERMNVRGRDSALSPEDYHDGGKGGRYHGLGGIPSPRGYHTANLVGNMMIIVGGSDGKDCFAEIWCLNLDTLEWTLLDLPESHKRLSHTSTQVGSYLFIQGGHNGGEYINDIRFFNLVNLQYEPRPTAGIPPSPRGYHSAILADSRLWVFGGYNGSQAYDDVFIADLAGGSYLPQVTSFSVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV86</accession>
    <name>A0ABQ8VV86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_810835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1060">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051807">
        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="28"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="129" mass="14377" checksum="7256D616C7AFEB00" modified="2025-10-08" version="1">MSSLRFSKSLLNKHSRLMSSMPSTKLHKFVLFAPDVKDSPRSAVQKQHREAIAPFVQSGVVKVAGMTVTPESVESENATVKPFGSCIIYEAENIDVVRKMVESDIYYTSGVWDQEKLVLVPFLPVTSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVB7</accession>
    <name>A0ABQ8VVB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1060">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051807">
        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="18"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="113" mass="12556" checksum="B0D8704FE9FB4424" modified="2025-10-08" version="1">MSNSARPKFFVYAPDHTEEGTFAKRLSIRNEHLARMKTILAAGTIRVGGVLLTPESLSAPPEGQKMIGSTFICEAESLDEVKKMVEEDIYYKEGVWDKEKIVVLPMMAATPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVM1</accession>
    <name>A0ABQ8VVM1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_485946</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="380"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="453" mass="50491" checksum="8AEC10044598E530" modified="2025-10-08" version="1">MRPFDSFDSSSSEGWMESLHNFDSYYSSQTQQPMHALDAFSQNTVYYSNSALFEETIDFVKYPYKHYDIDDELLDFPSPASSSASMLSPSSSSDYSVPESCSPTNSPQGNFPATMTCSPADIMPSTFSINDEYQESPSAQNSLELNTCDPFYNNQSLGSSTSEIDTAEAWVETSSWSVRPPASFADFSNPRAAIDKEELLVHPALPMSPQQVDGFSSCATTTQKKPAKARRRPNKKVQSQSIAPRLVSSSPADSYVARSSVSSISHNYHPLHSESSIDIVQPQASTSAVVSNVPITRKRKRSYQEEDFSYYNVASHHRAAKEQIRYTEDGVDCNDDDDPEYNCHIEDSEDDDYGGSQKQSARTKRSRASTSNISGSDPGFPCPEPGCERIFHRSADQRRHSESAHEHRRFPCIYCHAVLSRHDALIRHQVKARRCARRARQAQGRLPNASFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVR9</accession>
    <name>A0ABQ8VVR9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_120155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="411" mass="45964" checksum="ACDF2C2E8559AA19" modified="2025-10-08" version="1">MGNGRNHQRGPQSGTGTRRQQNTKANSPQPKSQHSYSAPPPPSQKPRPRPTPVHKGTPAYEQIQASRSQLPHDMDIAAAEQLVAFQHQGIVPRTVQHKHTSKLTTSQPHLTLDEQVFAGAMGISKAEMLKQREYERQYGLEDSLSDPEEEETSARLSTQQKQQSRRTKSISPAQESIRSLDIDDFEDSRPIFHDDEDNNSETSDGGDEVQKAWNNLVGSVEKFNIVFEVPYKTSQQNLTGITSHTAFVVFIDELAKRMETRLSLLSNISYLPSYKPKTRTTDVMLEGEEDWIILIKDAWDHVRNTRGKKTKAWTIRIFDKSPTETTGKGKEKDGGVKSGKRSIVSAPSDQLPASDSDADILVAIQGKNHCNACQAACYVLANGDHYRFDDEDMNTWVQLAVSTSYLLSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVV0</accession>
    <name>A0ABQ8VVV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_893937</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="266"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="378"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="473"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="218"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4498670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="565" mass="62372" checksum="3F730DACFC733372" modified="2025-10-08" version="1">MAGKDTADHYASESNRQEAVEHRKLQAPARSLAEFREREGRTYRKERLHALWQQICNTGHLHPVHRSTAPNSGITAAKVEQLRAAYEAELFGSCGSQSSKKQIGWTEFKSYALAKEVELWNIFHNELDINRNGRLEIGELDTALRKSNIVLSPATLNEFMASLTTNPQPHAITFSEFRDFFLLLPRKISPEEIYRYYQFAKFLGDDGRGAARVTMEGDVSLSAEDKPPVPPLRPLNVDQSPPVPAPYDGEEEDELDPEHDPAVIHHAALRFLLAGGIAGAISRTCTAPFDRLKIFLITRPQDLGVSSPSSVPTVNGVKAIGNAITRIYAEGGLRAFWTGNGLSVAKIFPESAIKFFTYESSKRAFAKYWDHVDDPREISGVSRFLSGGLGGISSQLSIYPIETLKTQMMSSTGQQKRTLIQAAKHVWTLGGFRAYYRGLSIGLIGVFPYSAIDMSTFEALKLAYLRSTGKEEPGVLAVLAFGSVSGSVGATSVYPMNLVRTRMQASGSPGHPQTYSGPLDVATKTWEREGWRGFYRGLLPTLAKVVPAVSISYVVYEHSKRRLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVV6</accession>
    <name>A0ABQ8VVV6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_899657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="850"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1017" mass="106563" checksum="2E1E41CB5BC3FBB3" modified="2025-10-08" version="1">MSTASVVQPEAPLTPGRQNDSLCTGESMTVLNRSTTPSVISFAEKETVEANSARLVVEIQRPISETNVNAIASSSEQLSFVSSSNSIQKPELVSSAIPTPIQPTSTTSEGAFTSLKDALMSSISHNNLPENIYLETDLPKHTGIKRPRTNEGGPGRVKRLRRDDEGEELPGSWSLSKVRNDIPVPVTVSAQDTPVQATIEADDENDEADLIRLFVVSRAGHVLPPPSFSTPTESQLSTRFDDASLSVRNLNTRFVRSKGEPGIKSNSDGEDVRINGGETELTSAVHITPDQEINNEEENATSMDIDRNITSLNSKAEIPLRKGWIFAALDQNIYRSKKKSSSDHPLSQILPRIRLGCFIPSEAKHSTNGQDPDRPTSLNQGGVNLNADEPPPTEGNIDLSGDADLDLDMYPDADDNSQVGIAVLDDGGDDGESEEDAVTEVELPIDELADDDAHEKQDIASLPSVQIAQTGTPTKSVTSETLSSLEPRRSSRKPVHKPVTLTNTPRRNVGRKAAGTDASISAANSMNNISATTSITSTPINAGGKKGSLAGRRSSLRKVETQETKETRVSTTATSTSKGKAKEEDVEMNSPSSSLVGHDLNSNVAGTESISAALNTSFKRTRRKSQTDRVKLASASGVPPARSKVYVNIEKTTVAGGAPESTSLKSVKAPSTGHSISTNKSSGNGTPATTSINGSYNPYSHLTTMGPPQQLASQSYFPTPTQTSNIQTIRDSLPSIQALPAQLQTYLLTALATGVPGILPPALGGSYSMQAGTGVGAVGNASVIPNVDSGSGFGIPGPLLAQPSTSVSSSALPAQAPSYNNYAPLQSASVPPMSAAPINHPASFAIPYPSTASLPTHGPGSTAELSGSSGSSLRQKKGKSHKTAKASATKNKEPSTMPETVNGNSNPDAGTMRVGPPRKATRTKTNKVLGKGKKKSEVVDGKAPAFASSSSSAVTNIGAASMTSGSGLNRKEGTVNEIPVPISGGVDGDGDIDAEGEIDLDIYAPYCVDINNANFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVY6</accession>
    <name>A0ABQ8VVY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-carboxy-cis,cis-mucoante lactonizing enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_809890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF4">
        <property type="entry name" value="CYCLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="Nitrous oxide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="55786" checksum="EE2A21F508031548" modified="2025-10-08" version="1">MNIDMMQPVQQVLSPSLNISSPPETLHVLSGSFRSLSLFLLAFSPAARTLSLLHQVPGFGPHQYIGTNRDKIKSSQSSETNLSTTTVGLAAYTTSWAVPPILSSWEITSDWHLNHLDNVPITAVSSYISFPHPYTHLYSMGGPTGEVHLLSPQSGSFLEKVQEILFVPPDKLADADKSRKALRYGSHAIEFAHLPGTNTRLAFVPVLGTNSIEVYTHDPDSGFLTHVYSSPSPRSGVEDGPRHVKVHPNGKILYCVTEHNNLLDVYSFRATGRSDSSTEWSNNPLKYLGTRSLLPPNLSYPSASIQTIHRFRGDTLMLGPSVGAGQWPTEIWATTRGATEDDRGWVSVFKLDQDGMFATSNPSGKSFSEEEGVERYETPTSGGKAHAIDLYPKSPSSFDIPYLEPRVGSPVWILLTDDSDYAVGEVRDGPSILSQPVKRSNPVGGVRVLEWDSWSNGGIREVVSWPSAGKWDCKAEIVDEEAGDTEQVVEQGSDEERLMRGGSHAVWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWD3</accession>
    <name>A0ABQ8VWD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_751532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="294" mass="32200" checksum="061D510B4A237696" modified="2025-10-08" version="1">MPASSSIKLNTGAEMPTLGLGTWRSQPGAVEHAVEYALKNGYRNIDTATAYGNESEVGQGIKKSGVPREEIFLTTKLNNPDMGRPKEALEYSLKQLDTPYLDLWLMHWPAPMTKEGGADKSIDWLDTWHEMEKLYKAHPEKIKAIGVSNFSVEYLKRLLSNSEVVPAANQIELHPSCPQQEVIDLCVSKGIAVTGYSPLGSEGAPLLKNPTVVKIAEKYGVKPGTILISLQANRPNVNVLPKSVTNERILANATIIDLEPADVVELNQIAKTEPFRACHPSWAGWGNLGFTESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWD4</accession>
    <name>A0ABQ8VWD4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_751060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="496" mass="56878" checksum="E48FB094E268E8C1" modified="2025-10-08" version="1">MSLPNDVWLQIIDYISPLAIQELYSVNSAFFNVAMDQRYQQISFSYLSRKMIWTLARLKDPPVAKRVRILHLYPHFVKDALDTMDLSSSQSLLSKFGELAGLIRDQKKLILKQKPRLPLKFKTCRDLMQVMMEIFSGLPNLTDYHILWCGLPSVGSDPALVLSSPLRLNLRCLRLEISLEKLQYMLSSFHNQSLPELEELDLFIRVEHLNADRYDNILLMLAHMISSLHSSLRKLTVQLWEPFDLSLLFAAISYLPLLDKLSLSIPMSFPNLGNPDGLIGFLNAHSNTLRTLSIRASELGGRSLMMHNELQLGAWMDQTFSKVHLACITKLEISLYLVPFESALLCVRTFSNTLTSLVFTGSHLAYEDLDLLTAAFPPSRQKQALHHARIGPVTLSPQLIDLFAERFPEMDKLELLVKSIVPSEGDVPLFCGRSNSDRDQDEGQIRRFIEEMKHRHYSDWKLRYLDLSSGSYPRLMNEEQFKSVFMQSILALRTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXM1</accession>
    <name>A0ABQ8VXM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_808263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046654275" evidence="2">
        <location>
            <begin position="21"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="266" mass="29498" checksum="0F92BFC82BEF33E9" modified="2025-10-08" version="1">MIGISSLMFLIATLHLTINAYRMVAGYVNHALLQGGAVAYMGDLRSWHYILKDTLYATQENLGSAAAIYRCWVLWGHNWKIIIFPSVLLIVNIVAGYMVCGLYGTVSPTNNIFDPRLTTWIKIFFPLTVALNVVTTSLMSYRIWCTHRQTSLYTSGNSQLISVMRILVESAALQLVVEIILLALYSSDVNAQYIVLESIASIVGITFNALTIRIKLHSISTAGSGHSMSFDGATQTIGRLPMRRIQVNISRDVEETEDNISTLSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXS3</accession>
    <name>A0ABQ8VXS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_728778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF5">
        <property type="entry name" value="FAMILY ACETYLTRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="23437" checksum="2775F76FB4A3B8F0" modified="2025-10-08" version="1" fragment="single">NFCFPIPEGLETEKLGLVPFVPSLHASIIAQCTDAATWHYLPFGPFPTAQALVEGFYEKRIHPNSGDTLFVGYDKTQTQNQNQGKAEGTPAGICGYVYTSPSDLYTELFVLVFPGYRGTHVASHMVGLLMRYALDLPSLGGLGLRRVQWSANVHNHGSIGLARKMGFRVEGVRRWARVLGEGGNGVERRKGDPRGECPGRDTVGLAICWDEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY68</accession>
    <name>A0ABQ8VY68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_806647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="297" mass="32588" checksum="2D1E7618A1FB1C74" modified="2025-10-08" version="1">MPLPEAPEVTELDVTNKSFPSYRPHVDDRSLLLKAREATNDQCVDLTLAQAKTIPNFWQKVQSYADERYGKGSRNILMYDKHYPDVHSAKVCVTSQAVQIKTTEGSPSCQTNNGTTGGVISGTHGIVSVMIQQGFTGTSSFTISEAASIGITNAFRVRMKFPDVVNTRGGPTAYATITNTQSANFDVSFNEMVTTTFNMTVLSDQTCQAMEVVHSCTLQGIGEIPFIASGKFWIEYDDKTYDHLENKKTHDGHYKFEVDFEDVLPAASQRTINAFFKGSFSTSSHGHYKAVCTGGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYL3</accession>
    <name>A0ABQ8VYL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_481264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="692" mass="77985" checksum="5DD65987A5ED638D" modified="2025-10-08" version="1">MVILRRSSMLNDEAESFLSTVMPTTKTVGVEYVLPKPESRISSKTHAIWAGKLILEMNEIDEAQTMSMECLLLPSDPLAGQISLTQGVIPLKVSMSYNDSKLVMKSRSFYRSEDLNAILAACSPVQEWGWLCAAKEEEARKFEQIADFLSHQKWVAFIPVAVEGKVVAVNLIYPSTFTHHRLPPVKPLVPNETGLIVSLHTWVINAEDCPLGDVLKHSVQRLDNAYDRRDFKLPRGVYEAYGEPGIKPLEGLKGPKLTTKHAVRMLELPELLHSYLVSGGERPFALWPPVDSEVFGLSPVPKIEREMLSTLLNEYPATVNQGTMGTEWDSSLRVIFAHVNSLVPGLGRRDIRDIPGLSEYRMMNDVRFFVYGSSDIVNPRFSDIIEEIWHIGGIVTFTPNALLSDPLGVHERILQIEEHDFWTCYILPAVIGMAVSIAYRDREHVIQKRIACEANKHMPPCTVSQSIDVDIDIDNGVDEPISCTCDGFGYEWLLDAIDEELISIVGAPPLQTHLGGQSSVTRQGASRDGRPRKTENWNQLSENHSASSSFPTYLDTSSLPSNFITQDQLRCPPSSIPVQYDDSFVPWIFQLFDSDVRDRSETLAFCIREFIQLCGNLPQEKWEDAIKREIIEDLGRLQISRGFREELRRFVIVTGSEDKGLQTDQSGIEWATVESFRFQDVTDDVQDIFDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYV7</accession>
    <name>A0ABQ8VYV7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Replication protein A subunit RPA32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_785072</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="7">
        <location>
            <begin position="67"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A C-terminal" evidence="8">
        <location>
            <begin position="175"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="29206" checksum="E7AF6AAF23DF1FDF" modified="2025-10-08" version="1">MSQGGGFYPNSSPFNQSQASPGGASGETKRSELSHSVRPLTLAQVIKAHQAHTDAEWTLEGNEVGQVTIIGHVVNVTEQTTNFLYTLEDGTGKVEARRWREQNSEEDADKWGDIQVNQVIRVTGHMKAFGNRKYVNAVNIRPSEDPHEIYFHTMEALTVSLSLHNGMPNGPPIGQKSPGNASAYAAQSSGMANDDMAEYRHLPHLQREIIRVLLAQPEHDEGGVHVGVVAKAVQKEGVTGASISDALDALMDAGQIFTTSDDAHFQVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ11</accession>
    <name>A0ABQ8VZ11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">transketolase</fullName>
            <ecNumber evidence="5">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_912902</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="359"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4501623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="686" mass="73246" checksum="7FB754CB62DA6667" modified="2025-10-08" version="1">MSSFTPAQSDDVSVATIRALAADVVTKANSGHPGAPMGLAPVAHVLYSRFMNINPKNSKWFNRDRFVLSNGHACALQYVLLHLLGYKLSMDDLKAFRQLDSLTPGHPEAGHTDGIEVTTGPLGQGFGNGVGLAIAQAHLGAVFNKPGFELINNFTYVFSGDGCLMEGVASEAASLAGHLQLGNLIVIYDDNHISIDGDTAVAFTENVGQRFLSYGWQVLHVDNGDSDFPAIYNAIAEAKLEKSKPTLICLKTTIGFGSKQQGTHGVHGSPLKVDDIQALKTKFGLPADKSFFVPPATYDAYADIGKRGASLEAQWNSLLGQYGQKYPKEHGELTRRISGELPTNWEQCLPVYKSTDAAQASRKLSEIVLTALAPVLPELLGGSADLTGSNLTKVKGSVDFQPPSTGLGNYAGTYIRYGVREHGMGAIANGIHAYGGIIPYVATFLNFVSYAAGAVRLSALSGHQVIWVATHDSIGLGEDGPTHQPIETAIHFRSTPNLAFWRPADGNETSAAYLVALKSKKTPSILSLSRQNLPNLEASSIEKAAKGGYVVHEVESEDLTIVSAGSEVSIALEAAAKLNAEGVKTRVVSLPCWLVFDKQPEEYRLSVLRSGAPILSLEALSTAGWSKYSHEQYGLPAWGASGPYQKVYEKFGITGSNIAVVGKKVVDFYKQKGGPVVSPLVKAFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ14</accession>
    <name>A0ABQ8VZ14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Indole-diterpene biosynthesis protein PaxU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_806576</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus outer membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMEM53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF30">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36603" checksum="1F240A2D3FB2DD18" modified="2025-10-08" version="1">MALGKSSPQITLASTLQRAGLVPIGNGIYLRREIPPSKSFSDATIYTKSFNPLLREPNIILVFGWMGAKLPHILKYTKVYEDMYPNATQIIVQSEPHFFWSSKRTRMNNLVPVAEVLEAHGCNGTRQESPSRDDNPPRILVHSFSNGGGLQMYTLGNLLRARLGSSSSSCRPSSRLSAVVIDSCPGNASFRGAIQAFTAALPKNSPLRIPVIIFITLLYGFGIIRHRIFGVQPIFERLKEALLRKGPEGGILPWMTEKTPRMYICSKKDELTPVEQIEEHVKEAKYRGLNAQIVVYEDTPHVGHARRYPEQYWGAVKDLWTQAVEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ52</accession>
    <name>A0ABQ8VZ52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CTAG/Pcc1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_808938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283">
        <property type="entry name" value="EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283:SF5">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT LAGE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="92" mass="10319" checksum="DF8142F605A3F3B1" modified="2025-10-08" version="1">MSENWHSVTLKIPFASEKHALIAKRTIEVDPELQPHAVKRIITVEENILIAAFSTLTIRLARLVANAFLENVDLVVRTLEQFGEEAENPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZE2</accession>
    <name>A0ABQ8VZE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_429549</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF9">
        <property type="entry name" value="AMINO-ACID PERMEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="497"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="526" mass="57089" checksum="B8A27C898DE660AF" modified="2025-10-08" version="1">MTAFSDDDRELVALGYVPSFKREFSNLATISFAFSIMGLCSSIATTLNTPLLTGGPSSVVWCWILGASMCLALGSSIAEIVSAYPTSGGMYTASARLTPKKYRARVGWLVGWLNILGQIAGVSSTEFGLANMIWAAVVIGKDGNYEVTQTKTVWLFVVLLIVHGCLNCLGTRWLARISSAFVFVNLGATILIIIVLLATTPRSEMHAAGYVFGSQGIVNQTGGWNNGLAFVFGLLSVQWTMTDYDATAHICEEVKRAAYAAPTAIFIAVIGTGLLGWLLNIVIVLCSGPLADLPGASGSAFLQVMYLRMGKAGSLILWVPVCFTAFFVVQTALQATSRTIYAFSRDHGLPDRGFFGYNSKVTQTPLRSIILCTLVSIIPGLLDLASPIAANAIFALTAIALDLSYIIPIFLRRVFQNHPDVMFKPGPFYMGGGMLGWAANWICICWTLFVCVIFSFPVTLPVTPETMNYASVITVGVMVFAFIWYILDGHRHYHGPQSNIKQDVEPEKEFGEVEKDSEDHNGSDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZG5</accession>
    <name>A0ABQ8VZG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="424" mass="44597" checksum="DCBDFE69B40D0D01" modified="2025-10-08" version="1">MAFEGSSLRGGYCQAHASGLHFAARYPEDLPFIDLYVLWFAPRHRRYRRSDLAATSLLSSILSTSGDLRRTAVLLITSLLSHSYSALRHCVTSGTVTRSQLVDIPEPIDSRPEPIAIDSRLEPIDNSSRLVDIPEPIDIPEPTDSSPESIDNSSGLVDSPEPIDNGSGLVDISELIDIPEPINSNPEPSDIGSGAIDSRPESIDNSSRLVNIPEPIGNSSGLVDIPEPIDNGSGLVDISEPINNGSIPEPIDSSPEPIDNSSGLVDIPEPIGNGSGLVDIPEPIGNGSGLVDIPEPIDNGSGLVDISEPIDNGSIPEPIDSSPEPIDNSSQLVNIPEPIDNSSGLVGIPEPTDIGSEPADIGFETIDNSPEPIDSSSEPIDIGPEESNPKKVGSGSTDISSKSSKSFPDSVDSPKIVSSEEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZY2</accession>
    <name>A0ABQ8VZY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_4607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="10061" checksum="4A7E33BDDE316EFE" modified="2025-10-08" version="1">MCGHSHFLPLIFISFIHVTPRIVPWLLIFVKQCSDITAISRNLNTQQHPATVDLALLPKFHMWFKIPFPRTRRNARSFVCTFLLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0W5</accession>
    <name>A0ABQ8W0W5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_810172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="63" mass="6849" checksum="6D8CE8819E8FCFAA" modified="2025-10-08" version="1">MSAFTISSLVGAIASLLHFFLKFIDANNSEEGLVQLDIILAILPVAAIVIFGTHKDLLNVYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W105</accession>
    <name>A0ABQ8W105_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">High-temperature-induced dauer-formation protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_928132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="914" mass="101631" checksum="1A7B4DA10D004860" modified="2025-10-08" version="1">MFSKIPQRLTAPLGLLSDSEKLAFRSQPGGLQKLAAVRNIPETDGYWNQYVVLFDSASEVFSLITPNDIRRALLEAPENVATLIRAISLRLFNLISDHTFPGPSSTSVSAFATSFIKAGTGTGERNATKEVLNCLRVLQRVLPVVFETEGAESGSFEVDVFWKKVEVDSMEEQPVPQTESPQFVIEDDEDSEDEAKSSAPQSAPTPHLKKQLPSLGERLFSSIIDLLFCCGFTLPMQIQKDHYKINYVIWEKGIGSMVDPGPGHQYDSNKTEVLRLLLVLLSRQIYVSASSLFSKPSMYTLHLVQKLPRRDVLTLLCSLLNTAMNSPQAQPITINSMAGKLPYNHLVFKGEDPRVNLVAICFEVLVVLLDFQSGSARDVVVGTNEQQMSAPTARTNEFRYFLMKLHRTQDFQFVLSGILGIMEQEVMNMNNILPGARRATPYIAENIVFFWKMIELNKRFRAYVLDSDQGIDLIAYLLCYNLEIKDKPQQHGICRALSYIVQTLSAEPTFGQRLTNPIRASLPSKFPASGTAADFLIHAIYAIVATTSGQLNSLYPALIIALSNCAPYFKNLSVTSSARLVQLFTSFSSPLFLLSDEGHPRLLFFMLEMFNSVILHRLSENPNLIHGILAAHKTFEDLGTFTLARGLREIRRVQVAKEDQARKLSLDDKRKSRRVSREEHAPEEKKNLVNNEDENDTDENSAASQIPHSDHDGGPTITTEPVVSPTPDSIPSAKPSEKSKGKMKQRRSSSSLDAGSLERMAAAGIGRNGFVPTPEWVASWQQGLPLDIVMLMISELLPKVQEMQSSQKASSASTILDFLGSVTLVDVLPPAPPLSPRRFVWSDASIVWLTSLIWGEIFVRGMTPLGVWNSTNIRLFYVKHSHNQQRQITETVSNVVGGLLGRTNSDTSVSRTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1C9</accession>
    <name>A0ABQ8W1C9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Telomere length regulation protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_872567</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.720">
        <property type="entry name" value="Telomere length regulation protein 2, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038528">
        <property type="entry name" value="TEL2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051970">
        <property type="entry name" value="TEL2_Regulation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019337">
        <property type="entry name" value="Telomere_length_regulation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830:SF10">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10193">
        <property type="entry name" value="Telomere_reg-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomere length regulation protein conserved" evidence="3">
        <location>
            <begin position="570"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="504"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="537"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="995" mass="110832" checksum="CBEA91C371DBEADB" modified="2025-10-08" version="1">MDVPSESEVRNLIHELQHPVSDYSTLSSLIAAPLDCLSLLPPVFRRYNINPLPSGSIRLPVHVPLLQHALLQHVLPNWDSELEKQGDLTLLDQYFCPDLFSFASPVAGKVAVLAYATLVSLPITDHSLRLLARLSKEFPLDRLHTAIFSQNDSSAKSNQKWEDCIQNIVAVPAKVGNYCGARKLNVPASLEHGVYFNNLSVRCESLIWASSKEHLASINYLLTKLVKLGVFPPQSPNSDSQPSFFDATLPVIRSRLSQDDTDSYSASWSRIFRGFESSFALQHVLASLFTCLKSPESSTDGSLLARVSVKHEAFFLTKLCPIQADDVELCQAVSAVMLGREWQESLSRVFVCWWADHKRWVLRSAYRRFLYLLLENVISLWSNPDHIKHSLLSRHRYVTSFLLLTISYFPSSSPEIISLVLSASFINGISVYINSMDNHIRHFGMLVAEVAAQRAGRTLDFRDWDGDDSDKLWARNLRALLVVRDADADARALNEEDNLYNVIPSGTAQEKSEPKKSAITIKSDEYDSDNSITGYDSTPSSRSNSPTPSELEEIEKDPSLNVGQKKSPRPVYLAQLGAMLRSMGGMAKDNPSEDADRIEVALNHAEELIRKKKDYGTELEENAVNLAYGLAGLQDNYDLDRFNELRQNAMNALVACSPRKAAPCIIEEFFKNQYSTEQRFVMLNALALGARELASLPIQTTSLSSDSTSFPSKRLPGSLHRKYLPSSATLPQILSGITRQAIDRGKEATEDKVPEIVRERRFRVQRTKRISEVDSSTLTARNFPHKQTTFIEVAADCFVAPLINRFWLFLRDEQTREARTAYHEGRTKYHGAGTGLILNSLVITHFLRTLTVLVHASEHTPEWLGFLAPDSLELALTLGTKPMSIADSSHEDSGPAEKGTKEASVLASALELALIVLDGCIQLDGGRSLSLDHATLLMSVSEWASVVFSRLEDGIKLKDGGGEQGANLRRAASGVILKADEIISKYRRSMIDIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1J6</accession>
    <name>A0ABQ8W1J6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_863026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="189" mass="21220" checksum="88FD0C3AF88E8FB8" modified="2025-10-08" version="1">MGSSADNNGSKKPNRKEFILRYLIGWEEPHEFGPISAEWDGSHASNPRIGVKWLMWFKQGLDCSVVPALTPTVSDICGSFLTASDLLPSLLEVWSLEWLFIMLCPHALFKTPVAFSPGTPMWSHATYFSKIILWGSKVTGHDDSWYFTCCLLLASSEKCMGAIVIIVPDRSVSMSNRKFPRRRRSECAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W2N3</accession>
    <name>A0ABQ8W2N3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_912890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="200" mass="21825" checksum="F12B1B6B05E63A15" modified="2025-10-08" version="1">MDLGDIRGGASWLGPDHYDKCIVGLLVPSVGILGKIVTVSMVRQRGFFYFSCTALSSSGLVREKEMSRYDPRRLEAEATEILAWIPRAASKRILLAVCPSWTPPAFYGLEVVFTLSRTQINKYTEAVPVQLFSIGLTVASTSKTSICQVDFTIALNLSPLFRKGYGDKEILTSSIEFCTASLGMISVCAPETVLSQQTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AJI0</accession>
    <name>A0A9W9AJI0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_511416</name>
        <name evidence="11" type="ORF">C8R41DRAFT_923575</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000013">
        <property type="protein sequence ID" value="KAJ4483077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AJI0"/>
    <dbReference type="OrthoDB" id="269919at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10470:FF:000008">
        <property type="entry name" value="Translation initiation factor 2B, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051855">
        <property type="entry name" value="eIF2B_beta_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4475867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4483077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="368" mass="40937" checksum="001A1BE301F2EFE5" modified="2023-11-08" version="1">MASDPQSTANQRIVEDLVSRLRRRQLVGSRATALETLLVLRQVVSKARFSNIDQLVNVIRIVGRRLVEAQPKEHSVGNTVRKVLHHIREEYHTASERPTVQSSFSIAKFVLQGQPRKQTPIPRSETRVPLKENDPDDPDSFARVLKPVLMEAIQDVFDELETVYDNISKNAKDHIHSDEIILTLGMSRTVQSFLKSAAHYRNYTVIVAETAPSYGGREMAASLSSAGISTFLVPDSSIYALMSRVNKVILGAHAILANGGMFATSGSLLAATAARSYSTPVVVCAGQFKLTPLWNLYHEYGALDFGDPSAVLGFEEGDLVDKVDVVNPYYDYVRPELLDVFITNYGDHPPSSIYRLLKETYDDEDNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWY2</accession>
    <name>A0ABQ8UWY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial distribution and morphology protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mitochondrial inheritance component MDM12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MDM12</name>
        <name evidence="12" type="ORF">C8R41DRAFT_129633</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="9">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MDM12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000142">
        <property type="protein sequence ID" value="KAJ4464355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21672">
        <property type="entry name" value="SMP_Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03104">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027532">
        <property type="entry name" value="Mdm12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26544">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="295"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4464355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="390" mass="43050" checksum="A8E6B940647AF820" modified="2025-10-08" version="1">MSIDLEWVKLDATLSLTLVNVLNRQLSTTTRPSFIGPVEVTSIEFGTTAPDIELVDLRDIYRDFLEDDEDDENELKATVGAEEEDEEAFEWVSRKAARREEGLAFQQQPHFGRGGPMNMFASTPTLHSPAMETWNPSLSSLVDHRPPYASWSSPGASSPFCYTASNNPINSNFAVPIPPYIGFNQNIIQNGPIPSSNESSLSNPREPSESPPPPPSTANNYPNLQLHLHINWHSDLRITLTTSLLINYPSPMFMSLPIKLSVTGLVFTGELAVAYEGERGRVHLSILDDLDPYGLAAERSKGDPPPSASATPPDDESESIHPPRPDKPLPVGQRLLPSIFIESEIGQTDKHVLKNVNRVERFIQDVIRKAVEEELVFPNFHTLVLNGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWZ9</accession>
    <name>A0ABQ8UWZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Survival protein sure-like phosphatase/nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_782794</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="5'-NUCLEOTIDASE SURE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457:SF0">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G01070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045043642" evidence="4">
        <location>
            <begin position="20"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4464383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="303" mass="31049" checksum="BB2DD7CB20B80755" modified="2025-10-08" version="1">MNLLSFGATLAFCVSLVQSTNIVLTNDDGWAVAMIRAQNSALSEAEYDVVLSAPAENESGTGSSTATPTNLTEPCEFDTCPTGSPAEGFNSSDSRLNYVNSFPVDAVRFGIQTLSPKFFGGAPDFVVSGPNVGNNLGTGTVDISGTVGAACEAAKEGIPSTAFSAAGLSQVAFTDLSNGDADTLASLVFSQLTVKFVNALLKNGPPFLPPGISVNVNYPASTSTSCASSSDFSFILTRIAPSNSVIDVETCGTDHLPGETNVVATNGCFASVSVMNATTKADVDATTQAFVLNRLSGFLSCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXC9</accession>
    <name>A0ABQ8UXC9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_860234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000144">
        <property type="protein sequence ID" value="KAJ4464257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046732064" evidence="1">
        <location>
            <begin position="24"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="20227" checksum="3085D2F40CC827A0" modified="2025-10-08" version="1">MRFNFAVYYIVLVFLFVTAFVQAAPVKSTDGTEAYSPEVQVRELRLDGIINWNIRIRFTSLAYAGADIPDSSHLPEKFHSVEERILKAIWNYLLLLPTANGIDTKFVNEPTDRSLQDKFVSCFVDLREVEQPHSRMLHLDVDKAGIPRVMQDSGGHFPFASMVVKGKAQVDREWPSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXM3</accession>
    <name>A0ABQ8UXM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ras-GEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_111742</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1919"/>
            <end position="2216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="232"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="538"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="622"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="724"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="803"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="872"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="937"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1214"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1479"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1647"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1789"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="258"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="642"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="730"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="751"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="803"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="944"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1214"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1234"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1483"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1503"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1575"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1791"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1820"/>
            <end position="1839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4464978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2216" mass="237732" checksum="02AC71D0FC24AE15" modified="2025-10-08" version="1">MASTSPTFSTSPPLSPSPPSLPPISSSDDYESLADSLTIPLSSMDSSTHFPPLPPAYTIDTEETFDKDLDVELDLDPGLPALPPGLGEFGTSAGATEQSPEQSGTPLRILVPIPTVSSAADSISFAFPDPTATMDGELSILSKPLPQESEADVVIAPDSTYVETSSAPWAMELKRRYDTLYGVNVIVRSPYAITAFVGQHGQKRYRIGHRELSAPGATAAAAEDILVLSNLSKQSKSPPPQTSPQSSKVGIGVGGGRSKSNSIRSPSGSITKPASKASLTNSEISSSRPSHKSQSFSRASKSGKRHSRGRISINALLGSGSASGPSTSAVGSTPRKLKKPRSNPDLSLSSPSGDPGFGYSGYGYTYGYGQHPPSSYNSTGTTVFGGRMHSLSVTATDMPHVVGIDPANPPSIPSSSLFPNPIHTTAPPTKLPERKGDSFGEIMGWRNHLIPSHMTGTSSGFSTSAPSTGYVAHSTHNLFFESRVGNMHAIDPAHAKSVSTTAINDPGLPLSSATGSGFVPRPFGPGVHFETPAILRSNHSHHSTHHEGKPMNGSFRASTRSRSGSGSESGSGYESGSTSERDLESDPEDPESETESDYGRFLKVQNSPWAHRRLKEMQSFESGLTATPIPPVTPTLAGTSVASASNTPRTNSSTTTRLEVDLGDDINLNLGEIVNIVDMALSENTGQKVIGRQRSAIKLVDRDREREKMVKARILETIEAESADTPNLTSASASVSGSQSDAASYPLSEDGFSQETVSPSSPLHDQYPSSTPQTHSSNLEPSDDTTFSLFNDIREAPDSSVNVIESRSQPDFSTPQTPQTPRVQMYSPSGLPPRLAKFATYSTEIFDVLQTSRGLPRLDLLDLRVSDQEDDADISISNDSTDDDSNRRSSSRSSSRRPPLPETVPVKLSLSQDGSAAPKDDPRFVIWGEVTPSETNGLTGCDASSVSHESSTSTNSSMSIGLGVKGKGRASDLQFTVGHGANGSASATLSDDGSGKTRVLLAATIERWLAQLTSDLDYDELLNFFLTYRTYISALDLARLLMTRFCWALGRSIAVSSPPNTGTSSNSFSPLSPPTTASTFSTATVKSEGSSTATATIASTAINTSIDDDVVRRIVRVRTFVAFKYWLITFFTVDFVPNRELRLYVANHLNDLAKELGDLGKEAELAGTEMGKEGREMKEMEMGMSKGAIVDGVSIVKKLKNVAKDCKKLYTRNNTVASSSRTQNSNNISQPPSDSRKDVGSEESNRTGKENLFGEKFAEATRKLSAASALTVLDTCDSDVDLDFIDEPSSASSPYSGVYGKTPVNNVHLGGASTLNLSTAISPPGPGSIPLSSFSILQRTDHAPGPEVFSGPMYSSSMNANATTIPHNALSRVLVKTLGRLGRWKRVLNSGGVAHGVSMHRSMTTGGLGKPYVGGGFSRMATACADVSAFDVELTVDSSDLLSSSGGVESYLRLVDGQSSQVPRNHLHTPSAALKLVKESSESPIATPSATSVTTPSPVTPTLLNSDSKTPNQHSFTDSLNEAHLPSSALSRSVSDDHIMLLPASDQSSEPPEAPQNRDSVAETESDYGAVTNVHEVRDSFTRSSRANEESFNDVSQGRESRATRRSSRTSSTGSFGEPLPASRASARFPAFTSPWQFDVVSLDDLSDNSSDEHDDANRPRDAPGDLPGIRRPPRRLPLRREFEFLERPETVSSMGIISRSSIVSASSASGQSTASHTSSSSAAGGLGAGIQQWQMNALKDSLMDDEEPGDVDEALKRLEGQINPQKRLEKASKVNGWVKTIRERLAAGDYSDEEPMYSDDDDDDAEVEAHEESEDSSSRGAQGTESTSATMLVSTDNPSPDADSVTATTPVVEQIDQVASPARSTDAKPAVEDAVPLEILQSRLSSELPSVTPERISKFVDPSIGPKVAHRSFVLLFKAEDLAQHFAMIDRELFMTIKFEELLLEDWMYCEEVDTLDWAQFLKDRARWKAEARLPEKTSALGAVRARFNLMFLRIAWKSYQQNSFNTLVAIMTGLQSSWVTRAMRRSMNKLSIWDKRMLADLKLFTSREDNFRHIRCAVDAINDAKPFEATSLASSVVSAVADSVNDQPTPSACIPFVGTYLSQLYQHNQLPVLVDPTAPNEVVMVDPVSPNFSSPAHPEVFSTLAPLPSSMHLEPLINVHRQRLIAAVIKSLVAGQHLASRAQFPIDKKLFHKCLRIRGLDSNTLHRALALKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYF1</accession>
    <name>A0ABQ8UYF1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000146">
        <property type="protein sequence ID" value="KAJ4464156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="258" mass="28419" checksum="8F430B3532EF9238" modified="2025-10-08" version="1">MEPDEATDTGTHGSTPHPLGWYRREIHEYYRYGLDDDGIVQKIVDNPDSNAEEVNTRGRARTPPPQKGALKQRDEKHASPGSATGAEVRGATPVTFKFSAPAPKYFLKESKRASSIVGDTYGPTKLQTTPFRSRASEGETAWYYSQSPADLDGPLPETPIPRILGTIYIHRSIKDGGYQIWVWFNRDGRGLGWQSVDLSNEQVAHPKVADRSLKLTAAGKPSWILNSTLTTYRSRSLKRSVSRSIEEAGAAESASSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZM3</accession>
    <name>A0ABQ8UZM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrophobic surface binding protein A-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF1">
        <property type="entry name" value="HYDROPHOBIC SURFACE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046379740" evidence="1">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="18471" checksum="BD060FAA864A72FE" modified="2025-10-08" version="1">MVQFTSLLTFALSLLLVSASPVKRTLAKIQSDITKVDALISTWDNSVNAFKGTPNQANAIHSAAVQLVSALNQATIDTKATSPLTTDMDALVLLGQIENSSPTLVGGLTQISEKSTSFSGIRGATAIAEQDIGDLQSSTAAFLNAISSITPAEVVSQATQFAVTLNDAYADALTNLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V037</accession>
    <name>A0ABQ8V037_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="166" mass="18145" checksum="D362427427FE1B33" modified="2025-10-08" version="1">MGRLRRSSQSKVNVSGCRTVKPSRLPPRSHPMILRRASAQSRPASANTVPPASYATPVPSDTAPATFNASLTSDSAALTTFDASSLDSSMSNRHDFVFAKQIHNYMIHSTGILQAQTETLVLLTQKLTSLNQIKESLEHDTEQEMNIRTAEVRCPLCSGLAWNPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0E7</accession>
    <name>A0ABQ8V0E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_726548</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000156">
        <property type="protein sequence ID" value="KAJ4463623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4463623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="74" mass="8524" checksum="3D2C2F80DB732705" modified="2025-10-08" version="1" fragment="single">MNRDPDVYTEPDRFLPERYSDFPMGPFESINNIYTFGFGRRVCTGRHMAENTIWLMIASVLATFTLGKAKDEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V114</accession>
    <name>A0ABQ8V114_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal L28e protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_714869</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="197"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4465900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="296" mass="34128" checksum="304329C81AE5312E" modified="2025-10-08" version="1" fragment="single">MQSDDVIWSVINHQFCSYKVKTATQNFCRNEYNVTGLCNRQSCPLANSRYATIREHEGILYLYVKTIERAHSPAHMWEKITLSNNYSKALEQIDNELIHWPNFMIHKCKQRVTKITQYLIKMRRLQLRQEPKLVGVKKKLDRRETVRERKALSAAHLEKSIEKELIERLKSKAYGDAPLNVNESVWQAFLDREKGDKGKGVANELEDMVNDETDEELEEELEEEMDDWGSREFVSDISEDEDEDDDGLSDLEDVVVRSFDQGSGSDEDGEDGDSNEENSKPKPSTLGKRKAPAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1C5</accession>
    <name>A0ABQ8V1C5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_50465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="68"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="24578" checksum="73D76A09B0A29670" modified="2025-10-08" version="1">MTSSSQNCITQNVAVAQNGTIVHNILNGITVKLCPPSSETYRSIIPQLAVLLKSCVDTNITMNFLQPFSIQDASAFWLSAEEKVVQMKQFVLVAQESQEAQEKDADDNDFRREKLEPPVILGCVILYLAQTPNAKHRGEVGKLIIGSEHRKRGIGKMLLDRMEDEARRHSLKILVLDTQTGSGAELFYERVGYSKVGVLPDVSLAPNGGQYTSCTFFYKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1W7</accession>
    <name>A0ABQ8V1W7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="499" mass="54281" checksum="0094192E5917DC18" modified="2025-10-08" version="1">MSFPSIDTTSSTSSVGIQPPLNRENPDIDELSPTVEDPSLGQLSLFKSIFGVGVSLARYVVDDPLWPILAAAGLPCSHCIRSKKEGSCLVRVFATSPGNVPKTWPSLAGSSRSMGILEFQQCQPSFPSTAIPRSSPVVRDPSPLLPTFIPKKRKRPVKVDPGSKVGSTPAPKRLRPVPSAVDSSQAEIAPEGGGTSDYRRVVLVLRPPPVPDSEVPPRLPEAVRPGPEISVPSSARTPSQSQGSGGLHRRVVPSGSSEQFAPPNAVEDSFRSRINTPPMQQRSQEPLRPYPRSQATSALKAENDRLKAEVEELRGLLTQARSQTSTLTSLLRDTSSSLDVRSKELEASRQSLEEVAVERTEYQRVLQQFRAIEAELPEPPSENLVTRFHIAQSELVVTKEAARNQKQEIAELRKQVAGVEQRSFDAYAELDSANACHALATTRPVPVLTRRCHTSYPPPVCPFTPPQVPPCTSPSVLTYLPKCHSPQHAYKILLTAKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V243</accession>
    <name>A0ABQ8V243_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Nonmuscle myosin heavy chain b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_897884</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01377">
        <property type="entry name" value="MYSc_class_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.360">
        <property type="entry name" value="Myosin S1 fragment, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.270.10">
        <property type="entry name" value="Myosin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008989">
        <property type="entry name" value="Myosin_S1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF857">
        <property type="entry name" value="MYOSIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02736">
        <property type="entry name" value="Myosin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50084">
        <property type="entry name" value="Myosin S1 fragment, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="12">
        <location>
            <begin position="23"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="11">
        <location>
            <begin position="77"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="195"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="728"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1640"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1960"/>
            <end position="1988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2269"/>
            <end position="2313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="921"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1290"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1460"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1726"/>
            <end position="1849"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="2064"/>
            <end position="2187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1665"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1962"/>
            <end position="1975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="2270"/>
            <end position="2299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="170"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4470286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2313" mass="264743" checksum="8942468C23D2C22B" modified="2025-10-08" version="1">MPAPRHSQSAEAARAAAAQAEFNEKKWVWVPDDKEGYLAGWVHNEDGEYGDIIMAAGGEIRRVPLFTLSKMNPPKFDRVDDIADLTFLNEASVVHNLRLRFGSGAIYTYSGLFLVAVNPYQSLPLYSDAIVHQYRSKRRDENAPHIFAVAERAWVNMGEERENQSILITGESGAGKTESTKKVIQYLAAIATDVHQGPSTPSHSRSPTLSSLQSFSTMPTTGLPRTNSTKRGHVSTTSTTGSGFALTAKGRLGLLERQILQANPILEAFGNAQTQRNNNSSRFGKFVRISFAPDGSIAGANIDWYLLEKSRVVVRSEAERSFHVFYHLLAGGSDLKGEEHIYSATTVSDLSPIDKLLLGGGVEDYEFLNKSRREVDGVDDREEWYALKAALDVVGFTASEQYDLFRIVAAVLHIGNIVVTSTRADDAVMPDPSQAERVCHLLGVPPVEFTRAVLRPRVLAGREWVTQARTGQQALDELAALSKTLYEKSFGLLVDRINQALDRPSSKSTFIGVLDIAGFEIFEVNTYEQLLINYTNEKLQQFFNHHMFVLEQEEYSREGIKWDYVNFGLDLQPTIDLIESSGSAGAIGILSCIDEECIMPKATDATFTHKLHSLWAGVGGDPDDPQQSHPGREKYEPARFEQGFLVQHYAAKVEYRTDGWLEKNKDPLNDNLTRVFASSTERYVSSLFADHVNTPISGAQTNMFSVGKKRGIKRGAFRTVGQRHKEQLASLMGQLMATQPHFVRCIVPNTNKKPGRVDVPLVLDQLRCNGVLEGIRIARLGYPNRLPFVEFRQRYEVLTPGIIPKGYMDGREACRRMVGALELDEAIFKIGMSKIFFKAGVLADLEERRDMLLFDLFSKLQAVARMWTARRQIKKILNRAVAIRTIQRNARVYGELRDWPWWQLYTKVRPLLAATRSDEELRRKEAELVLHKERAERDKQEREALENLKMTLEAEKNKVEDQLEAERALNLDKDTLLERSKKHEAELEEEVAELQADIHDLQSHLDRAMTMAKDSEQRHAEQRDMFDQAAEHLVRLENEQKQMRLHEEETLAELANQNEEIERLHNDLETLQKVSEDLKRLAVQREEDLSRARDRTDIAVKELEGKLEVEMRNKDILRGRTDTLELELRQAKEQVVEMDHTVTDYSSLIQKKDDRIAELLQELEQLAVEHQQASKEILELQSDIDTLAVELDAEKADRAQGDVSRARSQAELDELRTLLETKTSEETRRNEVEKSKDLELTNLRSQVVKMQQELTDTRHSALEIQGKLKVDLEQSARDLVSLQGSYDNLVQQEKKGKRGLESELQSLRSQVQKAKEVSRLNLSSLYPTAYHSFADIQSLDRQLSAAQNKYHGIEDVMLQLERDKTARERQLENIKKQLESETTRRSQVEKALSAQKTEIAKLKDHNVKVDRDLNKALKDLKDREWDIKQLESKQDKTIVEHVHVLEEAKREELQKNAAYIRSLTSEAEDLLRETERERMELRGKEKAVRNQEDRVARAVIDVEQERKARQEVELQVRRLQSELQNTSRHAEELSQQLLITQHSKESLEAELDHLVDETPAADSLAKIQRQYQARIVQLEDQVSMSDDARLAALRRLSERIQRQHADIRKLITDTGPSDSTFQSRLLHELQLLDDELKSDLSSRNVPSSRHDARHSTPSSKSKRNPSREAPRDITKSSDGQVVALKQQVQVLELQMAASERVRHHLETSIREMTADLENSDGSKQFLQQYRSRLAKENKRLAELLEEEAEARRSAEAAQIDGIQAVWSKFQKTIDEERQSYARLEETRKALHLQQRTMQSDLETQRTQLQEALQARKMLQSEVAETNAQLEVARSEITGLKRQIHNQQMEDDIASSTTSAMQADLRATTEAFKAKEQSYQQRLENAEIARVKATRAEASVRRTLSEIEKAQTDTVGKLKSNEDLLRAAHQRIKELEKKLQEEGNDSIDLVELNQRLAEELEDEKTQHQKDLEEHEFASNQTRKKYQELQSQRDALTRLREDNRKIRSDYDELQLRFDDEVYSSGGWRKEKERLETKIHDVSKAYEASTAAQTEQQSQIVSLHSQVRELRGVLDDVEADRALLQKARRALQAELEGIKLDHVDTHKLSTDQQFQKLFLQKQDLERSLDEQEDRVANAFDRMKKAEAFANECQIELGKVRVDNSELDRINANLENQVKELNVRIIDLETKSYASTSRPATLSRKTDSRIEEITSQLTGKGHAHRLSRDSKFDLDRQRVKLDEERKGYEMQLATLRKSMDELHTQDNLLQSAKRRAEREAADYKQKSLNLEREVERLRNRLDRPASAFGSPTSSPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V272</accession>
    <name>A0ABQ8V272_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxisomal dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_926765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000133">
        <property type="protein sequence ID" value="KAJ4464843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF57">
        <property type="entry name" value="DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisomal multifunctional enzyme type 2-like N-terminal" evidence="2">
        <location>
            <begin position="64"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="197"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4464843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="330" mass="35731" checksum="AC625F6E0477D7BE" modified="2025-10-08" version="1">MSSEIEKVIGFQLPDRPVTWFKRDLILYALGVGAKNTEDDLPFVYGKPTISLTIPRTVDKFIVDPNFAALPTYPVVLTFKGDSQELNLFADRMKGDNIPGMPRVDPNRIVHGSQSIEVLKALPLVSGSGWKWKTRYTGISENKTGVVLTAESTLVDPKNVAYAKLYSSSFNIGMKIAGNKFNKTIAGPPQAKPIPENKKPDWVYTDETSTHQALIFRLSGDYNPLHIDPAIGQAAGFGGVILHGLSTFGFAARGLLKTVCGNKPEALKLFGVRFTSPVKPGDALETQIWEVGPGPNGTTEVTFVTKNLRTGKNALGGGIAYIVKSPSAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V281</accession>
    <name>A0ABQ8V281_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="147" mass="16362" checksum="246C2FD4C3F27F37" modified="2025-10-08" version="1">MSSKVRILSSNTPCLRLLKQAVESKHEEVLQLRNEADSLRRKHSSKKRNTDAAQSDLAHLKAEHSHHISGVDDASISIIKLRTQLLASLSCGLADQGCIEAITAEKTEEFWSYLEKVKSSPTSTADVSLARTEDLKVPFVFVLHIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2J4</accession>
    <name>A0ABQ8V2J4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_50307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="55460" checksum="B3287767F09BC5EC" modified="2025-10-08" version="1">MKKKPRAKPCQTNLRDIWAWDSPVRRSAHRILEPIPAELYIMIFNHVKPRNDCYESKKTILKRTNDLRNMSLVCRYLCAEILPWLFESVVFHPGGLYNGVTTRAEKDVMSYIPFCRSIKQDEKFARSLALQVKQCSIRDWSDAPNTNTAMVKAFLNTHIDSLPHLTNLTTITLSRMPLAPQLLAHIRRLLHLTSFTIDRCDFAEILPKHVQKLAAKCKLKSFRLWVRSKDDSDDEDDEVHALVVKEFLPLIVNLSEFGTDSWLLMQALISCHDTLPPLLETLEILSIRDTKVLCEYLYKLPALTSLTMDSALSTTVYSNISLSRLTSLRHLTCPPHFVSHFSGSHELASLSFSTRRPDNSWVAIHNAAGVSWPRVDQLLAFCLPYTLALGIGLDPTSFLNGTGIVLDRLRKLTIISDECFILNSGGTPDQNGGAAMSKLVQILMKEARFPSLECILYRDDDNKEWTWREDSSSGKWKPVPEEDEDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V352</accession>
    <name>A0ABQ8V352_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_600562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="551" mass="58809" checksum="6221D243C14717E8" modified="2025-10-08" version="1">MTLAQRLNELAVANDEGLLNDDEYRILRQNLFERFAGNATVPTEESIVPASVTPLRRPPKGNPTIPENPSFSSSRLSSNFNVDILPNTTLSTRSPSVRSVKSGVASLLHRATNRGSNRDKSDTSSIYSITSTASNVFSSPHNHPHTRMSSHAGSARSLRKKTSSSSIGTEASISKKGQGQGDTASLSSRTSRKRAGLGFGQHPERSPSDGNYSPQTPSRSATSSLRRLAVPPSSFSPKGIHNSNLEPPREKGRTQDIFDDANLVTSTDIKREIAAVEAEGRRLVDAFNGLEVTTLAKRQRRHMGHHRVESRPATIVGLPGDGPLSIEIGTEEDSGGQGSSGVGVGSTWTLIPDNKLRFRATPTQTPTSAYLDTDVTSIRSGTSAHTSHTGRSIPRSIHRDASRTLPSKPSSGSASGSGAGSLHRKNSSSSLGSSIAAGKKRGGGLSPVPPLPISVPPLPSGLSGLSNLALASGSSLNLARSTGHLPMSSVPEDEDIDLLGLNGRDGREEMDEEIREIQRKKDDVSKRYAERLEYLRAKLKGAQLHEKLMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4I3</accession>
    <name>A0ABQ8V4I3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleic acid-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_853561</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000098">
        <property type="protein sequence ID" value="KAJ4468976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10289">
        <property type="entry name" value="GST_C_AaRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="TRNA-binding" evidence="6">
        <location>
            <begin position="243"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="45199" checksum="46B53FC0726CC468" modified="2025-10-08" version="1">MNFLTRFRFLPRVSTPKVMSFEDSVSRLGSAIKDLVASAAKDDPSLAGKSEKDQAEVVQWIEKVGQGDIVKADNFKDLNSVLLPRTYIATNYLTAADVALYGALHPIISKLQAPEYHSHPSITRYFDHIQSIPPVRKAADASSNYTLVSFDLVHTPKIDRTPEPPKKKEKKDKAATIDSASPPAPAAAATSTAEVPIDEGKIQKKEKKEKKEKPAVDAAKEAKKESKKGGGGKAAPADEGEPVPSMIDLRVGHILDVQKHPDADGLYIEQIDIGEETGPRTVVSGLVHYIPIEQMRNKYLVAVCNLKPANMRGVKSFAMVLCATSKDGKEGGIELIQPPENSKPGDRVYFEGAEFENATPLSQLNPKKKIFETVQPGFITLESKEAAWVNPATGSTHKIRTKDGVCVAPTLVGASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5L8</accession>
    <name>A0ABQ8V5L8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="632"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="761"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="846" mass="92121" checksum="6CA49F5025287112" modified="2025-10-08" version="1">MKPFSSISGFTVAGFIFGASTFGVNILFDILSFGRSAVSFVAIIFRPAFDPQSTHGDGLLVPVFIVPSPSLPRTAKVPPERSGPINKFVDVEAVASDADSSSDCLEESNADTNKYELDSVIVADDGSSIEWSASPPHIQADIERLPSLPRIRDSYVLLYMSTKDESADDMDVSSSPKSVFKDLALPVPKELYSNRVCQGTPEEKRPSSPKLYRSVIIFCPLLYPVTETKILSPIELSDDEYPVLPPKERLKPFLLRSPEMPSRQLHFTVSQFDGLVSISPSPPKNLTSIVVNGLVTFVFPARSVVTNPVSSRMDSPSSRPSLFLPDVVGIDHQVDEDSFDLCYPPESPKNTMSPIPAPSSSHGLSIKDYDNMDIDLPANFRSIPALRTPSPDLPSNPLEGWIPTPQSSSTLESRMRPVLPTTLSSKTRIFPSKLKRGMSPLKIPYGASPSPPRSLLSSPSHSNSDTSTVNTSPFKSSATGSPSSRLKGKDHLQFHPFSNSKRTTPSPLVTTPVKTPKPSAAGKKHRDAIIHRALTDALLSPSIPPIGFDNSASSSPPCKSRKELICNALSENDLMDSGDLAGFEEQYHGPQDVVPFIDNNLGENGVLNAEWIDPRFAASFRSMVDLPSRFDSDAWKDDPDNLSPLEPGHTPGKKRDISNVPNNIHCRNPLPFSRAVPIFDGRDSFVTAPAQLNQIGSRTYPLYKNSEEDPPTGCIVCVGYTAHTWQSSGSYKALPLSLLPSLQFIVVLALPPGYDGPDLPKSISSHPFPKPIYNTPTCTKDFPGPPRRKPPRSKPSSEDATGSSRISRHAKVDSDDDSPYLHAGGLKEGFEYHEDVMASKSNRNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V694</accession>
    <name>A0ABQ8V694_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_849328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="81" mass="9445" checksum="5EDBFD42A17B618E" modified="2025-10-08" version="1">MPWTFFYSVDSSRQSSNVPQDHYWLLLARCIYKCDPSDCNWNDSDNGSILSATFLREKLGRSQEEKNNKAAFQFCGHFLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6N5</accession>
    <name>A0ABQ8V6N5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidylserine decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.65</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_924852</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism; phosphatidylethanolamine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF17">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4470528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="43300" checksum="8CE1E7EF77589807" modified="2025-10-08" version="1">MHLLHHQVQDKPVEKIQPGVNNLSEAQDEHIAQGLESMVAHSETNHDVSHGIHMHGKNVFEVPWIHKMIPGIEKLASNYHIGNFVVVRESGERIFESMPIYARIGMHLLFYGSARETVLHYKSVAHLLQAQSIKQGTIYNSPDSAKSIASFVQVYSLDLDELLEPDITKYGCFNEFFFRKLKPDGRPVENAANPSGICSAADCRLTVYPTVDLARKFWIKGDEFSIPNLLQVPVDSSTAIEFDGASMAIFRLAPADYHRFHCPIDGVVGDTTNVPGQYYTVNPQAVNEPKFDVFTANVRSILYLTHTATGKRVAFVAIGALLVGSIVWTKGAEKGAEVKRGEELGYFAYGGSTVIALFPKGVVEFDQDLVKNSEEPIETLVKVGSSLGTTPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6P6</accession>
    <name>A0ABQ8V6P6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hsp90 protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_871219</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="6">
        <location>
            <begin position="154"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="665"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1111"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1138" mass="127365" checksum="2E9C8EEB8B8D1EE6" modified="2025-10-08" version="1">MGGRWTKVIPSRGRGGGKQCTRGTGGGGRIGAEDAGEVALLFSDAAESDSSSKRSELRFSTSPSQSRGTPPHISLPIAYSRRIEGLLEDRPKVVLQDLSPPAKQNPAATLHHGLERVLLPQLTSFGKRLTEHVHYQSIYLCSKKIRIYNFTHRDCWIFLRELISNSSDALDKFRYASLTDPSVLGTGKDLDIRIIPDKEGKILSIRNTGIGMTKADMVNNLGTIAKSGTKGFMEASSSGAGFYSAYLVAERAQVISKHNDDEQYIWDAGGTFTITQDTVNPPLGRGSEIRLHLKEDQLESSERGRVLGNAVRSMRASLDANQPGHLSQLNFAEAATRCQNLQELSIGLYGCVLPGDDVVGSPETLRIRRPAPSFDEDAIALLRTAKHYHPSFQQFVREPPVYYAVARYIAEQEPTSRRFWHMLMKRCPNLQELVIDGVSPFPVDARPLSYARWPNLRRLVLGDVAVDWLPGDALAAPDAKSPFIEFLEAHPNLQTLGLSRSNVIHTRLATMAPDTVKLRSFTGTLEQLQSIPHMHKYLDCGAFREPMRTRDVTALAVAGLLQKLTSLTKLKISFMLHSMYDSGNLLRSLIASCPNLTHLELACGHKPSFQLIRVRSHLHATNMACRKHFVGLNGDGCSGRSDWGKLTGCGDISTIFDLLALQEKEVSDDEAEEEEDTENKPKIEEVDDEEKPKDKKAKKIKEVETTNEELNKTKPIWTRNPSDITPDEYSVLYKSLTNDWEDHLSVKHFSAEGQLEFKAILFVPKRAPFDLFESKKKCNNIKLCVRRVFIMDDCKDIIPEYLNFVKGIVDSEDLPLNISRHSQEHVKKCMDMFSEIAEDKDNFNKFYEAFGKNLKLGIHEDAQNRSKLAEFLRFFSTKSTDEQTSLKDYITRMPEVQKSIYYLTGESLAATRDSPFLEVLKKKGFEVLLLVDPIDEYAITQLKEFDDKKLVCVSKEGLELEETEEEKKAREAETAAFSELCTVVKDALGDKVEKVVISNRITDSPCVLVTGQFGWSSNMERIMKAQALRDSSMSSYMASKKTLELNPSNPIIKELKRKVSEDKADKSVRDLTYLLFETALLTSGFALDEPTSFAKRIHRMISLGLDVDEEEEVAAEASTDDAPPPLEATASSAMEEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7E7</accession>
    <name>A0ABQ8V7E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_869516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045637938" evidence="3">
        <location>
            <begin position="17"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4477575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="329" mass="36685" checksum="1017AD7C94D3987D" modified="2025-10-08" version="1">MFLLSTICMVLEVVNTMGVLEGIKLETQGAFQPPTAWSGFRGANDRTLVQATIFSLEFILGDAIVVWRAAALWAFDWKIMFSMIIVLLGDFVFLLSFGTNAIATFFIALKAWHHREAFIVLPDSLSSSGSWKKSRSPAQKIMILFLESGFLYMLFWAACSFTYFPFVMGIKSPAFFMTDIFNQTRYQVVGLYPTAIILLIHRERSSWDTPEISTSLRTSFKAAAPPLYGPPMKQKSKHISTFRISTIGSSIISITEPHIIKEVDNPRLAKSWSSHLSDTGPSSPNVKDNTSQISSAFPLRSEPLALVDYTATQRAHGRSLSDETIAVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7F7</accession>
    <name>A0ABQ8V7F7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bifunctional 6-phosphofructo-2-kinase/fructose-2,6-bisphosphate 2-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_510910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="94"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4478537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="544" mass="61239" checksum="723AED825E4CB074" modified="2025-10-08" version="1">MSDAGALHSDAASRGIAEDLARASDALENMQASGELAPVVTVAPASPNVPPALFGAGGPMLKRFDESTVASRKGSNAPSPPPSVKGIGKKVAKPDYSEQKIVVAMVGLPARGKSYLSNKLMIYLRWLEYDVKVFNVGQLRRTKARQKAQKLGVKENHTAEFFSHSNAQATQSRDKLAEESLEMLIQWLKEGGNVGIHDATNSTKDRRAKIEARLAKEKGMTLIFLESFCDDPATIAANVELKVSQGDPDYKDMSPDEARKDFLRRISEYEKVYETITEPHLSYLRIKNVGEEVTMSRINGYLSSRIAFYLMNLHIRPRNIFFSRHGESQYNVEGKIGGDSLLSSRGMQYAKALPALITDNIGEKPLTVWTSTLKRTIQTAQYLPYTKLTWKSLDELDAGVCDGMTYEEIEQAYPDDYANRDEDKFNYRYRGGESYRDVVVRLEPVIMELERQENILIIGHQAILRCLYAYFHHLPQTDLPYIKIPLHTVIKLTPKAYGCDEERYTLPINAVDTHRPKPKTAKQPLTHSTTQRQYFVEEEIKPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7H8</accession>
    <name>A0ABQ8V7H8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_511661</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="355"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4478557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="492" mass="54647" checksum="A7882563322C10AD" modified="2025-10-08" version="1">MSHSFRITSALWDKIHHFASFPQTGVSLQQMVLFGQNPSQGTLLKASQFLSEELPVRLAHRAKELDELPHNLSAMPSIEKVKNWYAQSFEELIKFPPLPALSPEIRRSLFSPPSVANSNPEHQLPSSTPNPSLEHMLLVDDVANQNFPTSLDGSGSNGSLASGSMGFYGGANGSNSGWAIGNGNGNGNGTAVEGFNKLKLRVPMERRYFAAPLSSNIDWPPELRDYNKRFTRLLETIKTRHDPTVTTVAQGVLEWKQSQRARHIGLDMQQWLDRFYLSRIGIRFLIGQHIALNTQESHPDYVGIICTNANVHDIIEEAIENARFVCEEHYALFSSPPVQLICPQNLTFPYVPGHLSHIIFELLKNSLRAVVERHGVGSEGNFPPIKVIVVEGKEDITIKISDEGGGIARSAMGLIWTYMYTTMKLGPGEGLDEGFRDSDFKAPMAGFGYGLPLSRLYARYFGGDLRLISMDGFGTDVYIHLNRLSSSREPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7H9</accession>
    <name>A0ABQ8V7H9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_774621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4475127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25592" checksum="D0C268EC2626E1B4" modified="2025-10-08" version="1" fragment="single">HRHLAFEMLYNAVVGPTSINNIFFVSFLQGFRMPCIDGITDLYDIVRSFVGGAEEFVRSAETSIIKGFEDLNLTITVDLGATILQELVDACTNAGVSFQGKDFEQIFRDFLEETGAPCPQLLESIRGRLSPQINLDEITSSTFRMKLLCWSVSGAPRVMHEGDSLKVQLVEDDDPYYLPSRISRELQNAYISSGTSPYNPHSECKDARTAVHHWLLVQMLDAIGSYTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V850</accession>
    <name>A0ABQ8V850_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-ketoglutarate-dependent dioxygenase AlkB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_772031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032870">
        <property type="entry name" value="ALKBH7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052:SF0">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052">
        <property type="entry name" value="SPERMATOGENESIS ASSOCIATED 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="1">
        <location>
            <begin position="34"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="27354" checksum="A13E9B19A3E3E9CC" modified="2025-10-08" version="1">MFYHYRIFCRHNILSKRPFSATAQYSGTIPPDFHFIPDFFSVSEQRTLLSAALLRLDAAGSRRFQRRRKILLNALVSNCEGPPAEWFLPDDCYEFLEGHYDGVIHKFREMHLTSWPTNEILGLLPVLNRLHSLIPSHNIQTHLLHLASDGEILPHVDNVSASGRWILGVSLGSERILRLESCTHPDEGAEILLPSGSVYIQSDNVRFKYKHSILKSSASLSGIGQRISIMIRVSSFVIQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8F7</accession>
    <name>A0ABQ8V8F7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_842414</name>
        <name evidence="2" type="ORF">C8R41DRAFT_843178</name>
        <name evidence="1" type="ORF">C8R41DRAFT_847944</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="56" mass="6086" checksum="9D35EBBAD3C6EAF7" modified="2025-10-08" version="1">MPRPLTTAPFLPPSCLVTTRTAPVSAIRSHNPHRPTSVPPQNIPVTIFRSLDTSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8K4</accession>
    <name>A0ABQ8V8K4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_504408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="159"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="21715" checksum="0D925364F807023D" modified="2025-10-08" version="1">MSQFNGSLHFLNDAYRPFFQWQQLSAPSPSIFDYSHSRLIDLQEQQLQQGIQARMPLTQEPFPTLQYGGGDFPRVQPQFLHVEIPQDIVVGPQSGITSSPATSYVQSPYSAQGGHALSGTPLQSQTTAFLQCPECAKRLRSRQSLNSHIEAIHRKNKRFSCPYCHRPFSFQQALRRHERESRCPSSRNLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8P1</accession>
    <name>A0ABQ8V8P1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="2 11">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_771416</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="2 11"/>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF0">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51569">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 11 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="13">
        <location>
            <begin position="269"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="263"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU271113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4480360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="632" mass="69497" checksum="21F7C3910ECCF09F" modified="2025-10-08" version="1">MGFFSSKSSKSKSASTTATTTTTRVQVTRLVKRKSEPLPSSAPTPSRSVSLSTSPLSSPLSSPGITPPPDLKNPRKKRKSPEAGPSTESTRSRVSKKLRVDKPPKRASNTNSRASSRSTINLASSPLEPIFRSRSSRSRSTSTFPSLSSVSTRNLACEGDGEPGPSHVSSQSVVRNLHKSYKAYFSNPADPDDSSFEPESYPYVDLEYPNNAATERFLLLAPKDKDHYNPIMDLEKTLYTIVDYYLTPSQRALIGNVPSDLLTETVSPPPSPSPSPPNSTASHASSGSMSSLTSLESSSHNEFLQPRVNYCRAVQRAINTKDGPLFIKTIKKINNLLSSFKYPTPPSDPFEPVPKNSLKERVATWSNSGGLPFKVLMRIIDENYQRCVGPHISKLRKYEAFTSKVYGEILPSLVHEILSLTKLNQDSLFMDLGSGVGNVVIQSALQTGCKSYGIELVEGPAQVAKEMAEQFKARCRMWGVACGEIELEEGDMLESPRVAELLPKADVVLVDNKVFEEKLNEALRPKFLDLKEGAIVISLKPFVSSLNGLNARVTERNVDDISAIFDVTERPYYPGSVSWGNNGGSYYIHRVDRVGYAEIRQKFESTTRGRRSAATAKYTPSKNTDESDWFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V991</accession>
    <name>A0ABQ8V991_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_471179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="66"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4481797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="28570" checksum="39990C6861CE9CDB" modified="2025-10-08" version="1">MDNAWQPQDNDPSNSADGISIPTRDVGPADYSNGNGAPPRSSRSRSPGDRGRSGGEGGGDGDNPGNNLHVSGLSSKTDSRDLEAAFAKIGRVSKASVVYDPHTRESRLFGFVTMETAEEADAAITALNATELMGKIMTVVRARRGRARTPTPGKYHGPSKRRDRERPYDPRPYDSRYARDYDDRRGSRSSRYDDRGSSRRDYRDDRDRDRDRYRDRDYERYDRDYDRYDRDRYERPSRYDDRDRDRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAA1</accession>
    <name>A0ABQ8VAA1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-1,3-glucan synthase</fullName>
            <ecNumber evidence="2">2.4.1.183</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_921855</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[(1-&gt;3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19749"/>
            <dbReference type="Rhea" id="RHEA-COMP:11150"/>
            <dbReference type="Rhea" id="RHEA-COMP:11151"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28100"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.183" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058659">
        <property type="entry name" value="Mok11-13/Ags1-like_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058656">
        <property type="entry name" value="Mok11-13/Ags1-like_GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058657">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058658">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26122">
        <property type="entry name" value="CBM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26108">
        <property type="entry name" value="GH_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26114">
        <property type="entry name" value="Ig_2_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26111">
        <property type="entry name" value="Ig_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045322881" description="alpha-1,3-glucan synthase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="2327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1063"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1905"/>
            <end position="1925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1937"/>
            <end position="1956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1963"/>
            <end position="1982"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2002"/>
            <end position="2020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2032"/>
            <end position="2053"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2065"/>
            <end position="2087"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2108"/>
            <end position="2129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2149"/>
            <end position="2169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2176"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2216"/>
            <end position="2238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2245"/>
            <end position="2265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2300"/>
            <end position="2319"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="67"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1631"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1737"/>
            <end position="1777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1654"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1761"/>
            <end position="1771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4484056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2327" mass="259332" checksum="C171701A67C325D5" modified="2025-10-08" version="1">MGALAFAVGALALLSSLVNASPYRDDLTAWNLNTNKDATDPTQYSTTRSNTTYTPSPDNWRSLPVYTILLDKWADGDPSNNDYFGTMYEWDYRETQLRFGGDLKGLVARLGYLKNMGIKVIYISGTPFLNMLWQADSYSPLDMTVLDPHWGTWDDWVAAIDEIHAQGMYFMADLTVGTMGDLLGFTGFLNTSAPFTVNEYGAEYTYPNYIPWNFSEYRDFSVGNTKNTSCVLPTFYDDDGSVIDPATVGATYCMESDFDQYGDMEAFGVHPDWQRQLSKFASVQDRLREWRPEVMSKLTTFSCMVIQALDIDAIRIDKATQVTVDALATWASTTRQCAYDLGKTNFYIPGEVTGGDTFGSIYIGRGRTPSQRLQNITAVAQLTSDQSQYFLRDNGTVALDGCAFHYSIYRSLTRFLGMDGNLAVAYDVDINFVTAWNEIFVDNDFINSQTNKVDPRHMYGTSNFDVFRWPSLANGTQRSALGTFVTSLVMPGIVMYYYGEEQAFYIYDDTANNYLYGRQAMPGNLAWKRHGCYQLGSQQYYNMPLDKSTLGCHDDWNALDHFDPTADSRRLFAQFNYLRSHFVALQDGYALTELGNWTYYIQREGSNGTATEMGLWSISRSEMSGVQSLTGTNTNAVWMFFTNENSTNTWTYDCNDTLWISSPYESGTVVQNLFYPYETYTLEQSSSSYNNDSQAPWFGCLGSITMDGYGFKALVPVANWLSPPPALTAFTPGHDYRINSETSGTSVDISLEFNTEMDCNSVTNSITLAMSSSSTGSIPTISNANCANMNSSANVVVQGVSRTQWVWNATLTNFGDGILNITVNNPSSSSGNSTGTADVLLLRKGLPGNVMVFPDNDYNASALTKNGDDYIFTHSAYGADMFRYSWNFGQNWTNWTSWEDTTTLDLSSFAEANLFWDGDHVVVQYWCAATLSSSHVVHSDYGWSGYARRVPQLIATGVFNEWGSNKGIANTFSQSADGLWEFTFMYYWPSYFQVNVWGEDNYFYGDTDGDGVLDRLPPNSAAANYLNMSAPPLPHLSWTVFIDDSTMTWYLEPHGREGVAATLYALLVSIPLITGTLAVLIFMWSFYGIRYNQYGVKAKTSYFPILGALGGKSDAKDGAVVSEKKVHRQNMDIIGWPEDKNKRRKVLIATLEYEIIDWKLKVKIGGLGVMSSLIGKAMSDVDLLWVVPKVKDIEYPAGDPADPIEVIIFGEPYLIEVETHTLDNITYVILDSPVFRAQTKADPYPARMDDLSSAIFYSTWNQAIAATVRRNPTVDIYHVNDYHGALAPIYLLPKVLPVCLSLHNAEFQGLWPLRTKEEMKEVCSAFNISKEHCTKYVQFGNTFNLLHAAASFISVHQKSIGVAGVSDKYGKRSWARYPALWTLKHVDSLPNPDPTDIAALDESPTDAKKVQIDQSAEAARPEHKRQAQEWAGLKQDPDADLFVFVGRWSKQKGVDLIADVMPSLLEKRPSIQLITVGPVIDLYGRFAAEKLARLMELYPDRVYSKPEFTALPPFLFSGADFALIPSRDEPFGLVAVEFGRKGALGVGSRLGGLGLMPGWWFPVESSSTAHMLSQLTKTIKMALKSTEDERALLRARSAVQRFPVVEWRQRMEDFHRRSIIASRDLAGADAWRESDCDGGTGGLRPMADTDDWNPVNQSQPSQPAWDQQSGLASPMGSPRLNNSTDSLAMDDPAHAPPRLLNSNSVGDEGDSVSHGSHNSSADYDDFLSRANRIIARDQRNAPDPFLEAPNGDFKRPARPFSSHSRNSSASSLADVADEHSSSPLNKAIASFTDADGGVAADFVQKLQELNAKNSEHELSIEKYLTKSEEVFFGKVKKDKLDSAASLRSSQRDSVWGTPDPSLYSRPSSPMGDGVAHADWETTLPQPEQVPMTGLQIFMAREIGGWPLYTIIIALGQTLCATSFQITLLTGHNWQSSAQLYIIGSIFLVASAVWYPLFRFKPSVYVLAAPWVFFGVAFFLIGLPSISSALNPSHKILSNVATWFYAVGSAAAFLFFGLNFGEEAGAATEVWMLRACIVQGSQQIWVAALWYWGYKLNTESDSYTPPWWICVIVWPLAVMCFLFCYLMLYGLPEYYRQTPPKVPNFMKTLFRRKIVVWFLISVVLQTYWLSGPYGQNWYFLWNSDIPTWKTLLLVLAFFIGVWSLMLFVLTHFSKTHTWLLPVFAVGLGAPRWCQILWGTSGIATYVPWAGAGGPYLAVGLWLWLGVLDAVQGVGLGLILLQTLSRLHVTVTLAFSQVLGSAIVMIARATAPDALGPGTVFPDPGIWDPQNGLSGSPMASPMFWVCLVCQLIIVAGYFWFYRREELARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAE9</accession>
    <name>A0ABQ8VAE9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_921894</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="313"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="386"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4484102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="437" mass="47423" checksum="6798993B6D60CC76" modified="2025-10-08" version="1">MSSSTTTTNQLTKSDEQNPSRMTDIALRKKKNADAQAAFRARRTNYITTLEETVMNLESVVRVLQDSCREATTEAQELQQENNQLRQALRNQENFWRASWPKRGQNSETESEFPSYPSPPSTTFNSTQYPDNSLGFNQYPASPSVSFNHQNQPYTSWTQTSSHSSNSPHFVESPTLTSASGMGFVGDRCPDDQKVPLNSLEPTVVPYVFPTSRSISPSSSTPPSSSTTALTSPFPFAFNDAQGAAQDRPGFEYRRQTTQSHGAEVISLHGGTADISAIASSSGNDGGVRYRLGGNNRRMDAILDRTSLLPLLPPITSGTAGSENDSQHGSQHGSDGGDSSYSSQYQARPRRITAPSSRSPSPGVAPLSGTLAVIKAQAFGALRRTRVRSKRPADGPAKVSRDVLESRGIVSADPLLQPGPVKRRRMNDDSDDFDAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBI5</accession>
    <name>A0ABQ8VBI5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_868314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="24558" checksum="1561E28A7BACD46C" modified="2025-10-08" version="1">MDLEPSLPFPIPVLSSLSVSLPTRRVHSQMAVRTLQDLVDDSPPTEYEIYNVFEEAAPFSIYIHDFWMGRANCPLFAEQVLLSAESLSLSLPAFRRDDLTQQWGVPPEHRSSAEGVLKFERFPALPIPFCLRFREGSAMMRMVSSKDLDPFVSLRGQNVLSGVPKTVSPPKVSDVISPSPANKAQAVPPRALRRNREIESLKADASSFCEYLFNFLISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE55</accession>
    <name>A0ABQ8VE55_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S5 domain 2-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_896216</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11370">
        <property type="entry name" value="RNase_PH_RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF0">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="2">
        <location>
            <begin position="40"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="3">
        <location>
            <begin position="174"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4487464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="278" mass="30353" checksum="0B88573749C9C63A" modified="2025-10-08" version="1">MSADRLLLTLSDSSDSSDGHSRIEILNTGGYRSDGRRQYELRTISIDLSPQGSGADGSASLTHGLTQVNVCVFGPREAKMRSQTYHDRANVNIEVAIAAFSASERRKRGRGDKRILELSQTLKSTFEPVIQTSLYPRSQIDIYIQVLQQDGGLLQACVNATTLALANAGIPTYDFVCAVTGGVHSTSPLLDLTLLEENDLPNVTVAVMPRSGKITLVSMETRLHVDRFEEIFRLAGEAGKVIHREMRKAVKDRTEQLVASMQSVGRPSTGADVGDNEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEG2</accession>
    <name>A0ABQ8VEG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_895881</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4491676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="612" mass="69414" checksum="CF5AD70592606BE4" modified="2025-10-08" version="1">MFSDVPPGISFLIKRLPQLILPPVVVFTTLSTYRSYVDHNVPSGWFLYMLSYPLALSVGIAYTAILKRVVAARMGAALLPEPPFMEDPTPGGLLFLYGIMKEYGWLNPLASKDKISIVLPGQAVANRLRSTGPTFNLRIFFEDRLVTSEPSHIKSLLATQFEDFEKGQDTLTTLNSLLGTGVFANDGTCRSLTIVLFHRSITRPFFSRDRITDFDIFDRHAEEAIRKMKARFKEGYAADFQDVVSRFTIDSATEFLFGHDIGTLSDPLPYPFFHPSHSVSNDSASPLTQTFSARFSRSFNEAQTATAVRIRFGDMWPLREIWKDIPKEMMKVVHGLLDPIIQQGVQRSKLAQESKATALEMEQEEGETVLDHLIKHTDDPNILRDEIMNLAVAGRDTTASLLTFTAYMLSQHPDILRKLRSEILAIVGPNRRPTYDDFRDMKYLRAVLNETLRLYPPVQSNKHTTLPPINPGDKPFFIPAWTSVFVMQRRTDLWGPDALEFDPDRFLDERVHKYLTPNPFIFLPFNAGPRICLGQQFAYNETSFFLVRLLQNFSDIELSETSQPPDSRPPASWKKEGGIKATEKVKLKTHLTMYVAEGLWLKMGEACAVEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFA3</accession>
    <name>A0ABQ8VFA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cupredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_411380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4487495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="21868" checksum="48E6EBBE2BADB4A5" modified="2025-10-08" version="1">MDAGTTYHNFFDPSHMNTSSTPQANITFVFVGIGNYSITQSSLESPCTPLDGGFDSGLVHTENSSTTARATLTLGTVGEIWFFSQQSDPHWRCNSSIVGALNPPVTGNLTFASFFANTNATGPTTSRSATAATLNPSTVVPRTSSLSETHSAIAMASTASTSYSPAMTGHSVTPGAIVGGALGGAMVVIVALLVVLFSLREREARRRTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFM8</accession>
    <name>A0ABQ8VFM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_831517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="94" mass="10412" checksum="3E445C6232819688" modified="2025-10-08" version="1">MTGDLLSDTTIPRTTSFNEVVTEDFSTVVTSACRLAVHSQFMTGRELLAARSATPALLFPSKTDKRTWNRSSASSNIENLFRTSYLSRSIVHVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGJ3</accession>
    <name>A0ABQ8VGJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_834693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047286237" evidence="1">
        <location>
            <begin position="24"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="135" mass="14843" checksum="7F21D01A0A1CFEF4" modified="2025-10-08" version="1">MRAAPTTVIFLSIILVMVNPSEAVSIPKRIKNVMTLIKPKRVPAPSTVSTSGMYDIDAFMDEHCESGFVGTLSGSIGSGQHDLNREGHCLEFMAPFPTECALDVEMSTGQVRRYRQNYDEGDMLKGHFLSLSVDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGJ4</accession>
    <name>A0ABQ8VGJ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_895635</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="575"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="782"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="686"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="105"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4493345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="844" mass="96046" checksum="22E99DF2CEC23872" modified="2025-10-08" version="1">MSDDYPSLLRSEQMSLVQLFVPTEVAHDTVAELGELGNVQFKDLNPNVNPFQRSFVGEIRRVDEMGRRVRFFSTQIEQEKDVVPIRPLYDSAPLIAVGPRAPQAMDELDVTLAAHEQRLTQMNETYQKLSERTKELIEARHVLRETAVFFDKAQDHQTDIRTSFDDSSAPLLQHDDRENQYSLGTSVQFDLEFVAGTIERVRVPTFERVLWRVLRGNLYMNHTDIVEPFVDPVTGAETRKNVFIIFAHGDALLAKIRKVAESMGATLYPIDANADKRSESLREVEGRLEDLQNVLYNTGSSRRTELTKIGESLRSWQDVVRKEKLIYETLNLFNFDVRRKTLIAEGWVPTRDITTIQLALRHATEESGTSVPPILHELRTQKTPPTFNRTNKFTEGFQTIMDSYGVASYQEVNPGLFAVITFPFLFAVMFGDIGHGFIIFVAALYMILAERKLARVDLGEIMGQFFYGRYIILLMGLFSMYTGLMYNDIFSKSLHIWHSAWDFPSNTTDTKLVGIDNGHRYSFGLDPGWHGADNNLVFVNSYKMKMSVVLGVIHMTFALCLQFPNHLKFKRPIDIYANFIPQMIFLQSIFGYLVICILYKWSVDWSNATTQPPSLLNMLISMFLSPGKVDPSEQLYAGQPFVQVVLLLLAAICVPWLLITKPYLAWKDMHKIKEQGYVSISGEGDGNGIHRNSSDEVLEGEEEGNGRDIAEDGDDGEHEQHDFGEVVIHQVIHTIEFCLGCISHTASYLRLWALSLAHAQLSEVLWSMTLEAWLEPNGVFDWIVLIVMGVFWFVLTVFILCLMEGLSAFLHALRLHWVEANSKHFEGGGYAFTPLTFANPDSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGK7</accession>
    <name>A0ABQ8VGK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HPt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_385129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37015">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37015:SF2">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="33286" checksum="767F09B7FCEE7043" modified="2025-10-08" version="1">MTNSASAFGQTFQYITAIKLHELEKQRETCMKYVDDTLADVKIAKNPVSQLDILLNRIHGWKGTGLTPLTSPHIHLDNYKAWLHLARNDPSISSSQVSIWISTLEEQLKQAVTRYDYAKLFGDLLKEWLQSGDSLAIAEPSVDDEATVSDSADTKTERTERIEQRDRIQNLIFEPKPIHTAALHAYLSDLFTSTPEATDALETLRSQLRSFGDEILSESISDESMVPLIRSLLSRDLLSAEKTAILKSFLDNKIILSEVASVLSMQLARLDTWAWPEEGVPVEMRRHLSGKYRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGL6</accession>
    <name>A0ABQ8VGL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatase regulatory subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="287"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="760" mass="82967" checksum="81B77F05A334B6B9" modified="2025-10-08" version="1">MTISPSGSLTSNTAGSALPLLPRRSSASRVYVRPNASGIISPPRVTPSPVKIMVQQATPPEDDRAAASTSGNVSDSASSSSSSSSSNERLSPVRVRGNRGYRKNLPTDPTSPTLAIPRSKKDRAPSQPEKLKEQTERKSSTSDFGIGAPLKLSLEGLPKTLVEFPSIEQSIHKSAPVAPVIVVRKKSGQLVKPSLKTSKSTFKSSLNVTPGGFTKSEPATPTVPKAVKFDSRLEHVKLFLAEQRPLAVSRDGSPTDDTSGTESDFPFFIFGDRKNKILKMVVTNLPLSLNENTDLVLEEMKLGLDEVSIVGRIRVRNLSFQKWVAVRFTFDDWQTTSEVTAKHIESPNSEFDVFGFLIRLSDLIARIEEKTLVLAIRYNVNGREIWDNNFGRNYVAKFSKEMPNKSVDSPMVTPSASDKDIISSGSDISDLHSRLEKVVKKMDADNAAISTSLYSRPTSIPSDFKTDTPLASRYDFGVSLKNSRKSTSDVPSREHTRMHSYPIIASHSLDTASWPRKHRSLPKEKPVLGSPRDLGDSFRPAPFVPSDSEEGPEHTNRHHQRGYFDMSPLSSSSSVKMTPPGTPRLRSLDDTTPLASPRFNSLPSMRPVSPFHSPHFGFALSPKHVAIAEAMDGVSSLISPPLSNSTTPTDSPPFVTSPLDSAPGTNYNQFLDRFCFFTGSDSGGTSSDESATETISRSSSTSSMDDFLSSPRLFDPAFRIFAPQPVTQTRDDISLRTSSGLSMQDPYPESESRSVTPLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGM6</accession>
    <name>A0ABQ8VGM6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_795039</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00944">
        <property type="entry name" value="CKS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00945">
        <property type="entry name" value="CKS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4493397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="122" mass="14600" checksum="0755DAFB502B61B0" modified="2025-10-08" version="1">MSAVPESSEEAAKRQAEQKKLEEILDKINYSDRYTDDIFEYRHVILPKQLLKYIPENYWDQRTGALRLLEDKEWRSLGIQQSLGWEHYEVHVPEPHVLLFRRPKDYVPPTQPAPRAKEARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGU6</accession>
    <name>A0ABQ8VGU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_326058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14634">
        <property type="entry name" value="zf-RING_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4493318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="340" mass="38853" checksum="E79BFCAEA1DF93C8" modified="2025-10-08" version="1">MAEALCDICYQVFSLDRFWFSTCGHGFCETCTTSLEKTRTCPSCREPRKKANIHKIYFTLPEEQENAIDVQSQSQTLARSMTNIHPSSTLSSVDRVVEGLKKFSGKLGVDAETASNLLGVAKDMEERLRPIFFQFQLERDEKRTLQEKVNLWQHRVTQVEASEVEVAKLKKELERAKRANQGMAAENCRLTKRLEAEVTESEKLRKDVIDERRLNKERDGLVQQLERELENAGKLAGLTNKKLKVLARSSNRTPVANSADNSLIGHSMKWESFLKTMTKQGFAYDHNSSGSSVCFVPLDSTKRSIAFHKPHPDNIIGPVLLKEFNKKFRKYYGRDLVNFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH06</accession>
    <name>A0ABQ8VH06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Metal resistance protein YCF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_764166</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="912"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="954"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1025"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1053"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1144"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="260"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="593"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="915"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1234"/>
            <end position="1471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4494217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1481" mass="163688" checksum="F6E909028E1EA6F8" modified="2025-10-08" version="1">MATCSDPEGWSAVSQLRGFDTTPCFEEGILLSSLYAIIFLVGVVRTLSACLSPPMNRTSKSRWLLRGKIFLLVSAFFTSIANLAIILFLHKSVPLLQSYILEPISILGIIFLTYYNHTRARKSSSALLIYWPIYTITVLIWVRTAVARDFNLFRLPVALKCAACVLGFLSFALECIGPEFDQKSDLHESPILTVNIFGNWAFSWMTPLMRKGASQYISEADLPNVQPQDECDKLGQRLKDALKKHSLWKSLFIAYGKPYAFAALLKLLSDCLSFSQPQLLRMLLAYISLYQSARFGPWSVNVAKPDPLEGFMYAGLMFVVSTSQTVVLNQYFQRAFEVGMRIRSGLVDVLYQKALVLSNDELDRSSGDLVNLMSVDATRLQDFCQFGLISISGPFQITLAFVSLYNLLGWPAFVGVAIMVFSVPLNTFIARILKRMQQEQMKNRDKRTRLMSELLANIKSIKLYGWEFAFVRKILQVRNEQELVMLKKLGIVTSLNQMLWGGIPLLVAFSSFAVAATVSSKPLTSDVIFPSISLFMLLQFPLAMFSQVTSNVIESVVSIQRLSDYLGASELQSDARKFSEMLHVENGQEVLSIKNADFSWSKTAAQPTLEAINLSVRKGELFGVFGKVGCGKTSLLSAIIGDMTRREGEVTVKGSIAYAPQNPWILSATVRENILFSHEYDETFYNMVVEACALTPDFALLPQGDATEVGEKGITLSGGQRARIALARAVYARADLVLLDDCLAAVDSHVARHIFTQVIGPQGILASKARILVTNSIAFVKQFDQLLYLRRGIILESGDYTSLMSNEGEVSRLIRNHGSTSSSGTSTPYLIGDASGSVTPVEENNNTLADEKSSVILSEKLRRQTSFSKPKLAALPPTRDSVSAGLSQEHKEQGQVKITVYMKYIQAASKTAFGLFMLATVAGQAVSVLGNFALRAWGEHNRETGSNSGMFKYILAYGLFSLGQVLLTAAAAILVWVFCSIRSAKQLHDNMLDGLIRAPLSFFELTPTGRILNLFSRDIYVVDGILARVISMAFRMFVTTFSIVIVIGSSFPLFLLAVVPLGWFYLTVMKYYLATSRELKRLDAVSRSPIFAWFSESLSGLSTIRAFNQQSIFIANNQRRVDRNQICYISSVSVNRWLSIRLEFVGAMIIWIVATLACVALVTTGVDAGLVGLVLAYALNATSSLNWLVRTASEVEQNIVSVERILHQTEVQSEAPLEHADQTVPQPWPTSGAVEFRQYSTRYRPELDLVLKKINLTIQPSEKIGVVGRTGAGKSSLLLALFRIIEPVEGTIFIDGVDITKIGLHDLRSSISIVPQTPDLFEGTLRENIDPVGEYSDMDIWNALAQSHLKEFVESLPEGRGLDEPVREGGSSLSSGQRQLLCFARALLRKSKVLVLDEATSAVDLDTDKAIQDIIRGPAFKEVTILTIAHRLNTIIDSDRVLVMSAGEVAEFDAPEKLLENKDSIFYSLAADAGLAPVVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH50</accession>
    <name>A0ABQ8VH50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CBS-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_763704</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="60"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="127"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="234"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="311"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="6">
        <location>
            <begin position="462"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="419"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="649" mass="70100" checksum="FA9CDD1EFF0AC795" modified="2025-10-08" version="1">MSSLSGFQSETRKKTSKRDEAIRKKIESELSRKRTISTTQTQQRRRGNKASAQKGTVAALKPSPALTVPENITVAEASQLCAAKRTDCVLVVDDEEGLSGIFTAKDLAYRVTAEGLDPHLTPVHQIMTRHPMVTQDTTSATEALQLMVSRHFRHLPVCNEDGNVVGLLDITKVFHEALGKVERSSAASEQLFNAMAGVQSELGNVGSNPQAAAMLAWADKLRERTALPDLTTVMDSRTQPATVGPKTTVREVAKLMKERRTTAVCVMEGAATSPGMQTSSKVVGIFTSKDVVLRVIAAGLDSGRCSVVRVMTPHPDTAPPTLSVHEALKKMHNGHYLNLPVLEDDGRLVAIVDVLKLTYATLEQMNAVSAEQGVGNETDGGPMWGRFFDSIGHDDTESMLSGSHIPPDIRALQSNTSLSQLHSPRSEVHPNDSASVVDDESAVSYQNQKGTPSISAPPPVDDGTYVFKFRTPSGRTHRFQSRHDNVEHLREIVAGKLTTDPFFTDFKPTDSNVVPPDPIDFLLSYTDADGDTVLITSDHDVSDAVKIARSSGSDRVVLFVQGGKAWEDAGARDSEVKAAETAAAAKQEIREVEKQELPIPPIYAPPPPPLPQEQVLGIPKDLLLPASIGALAVVILGIFTVSRLSSSHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHX1</accession>
    <name>A0ABQ8VHX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="542" mass="59757" checksum="C14CA4D4525371F1" modified="2025-10-08" version="1">MPITYRQRLNTSTNSHASLTPSIQDTDSSIVLSDLLRSGESSRLRRRGAVRLDSVHRHEDPRALNNTSNLLDEEDNYLQLYCRECDTPAYQPVAEPSSQTPFRPSIFPLSSPPHPSPQCTEFKGKTRASGPQSLGRTLVHDRVMAQRLPHIDASLHVHPPSSFTYSPSAAQVIAFLTRTQHSSSANGLSEEELDVSGEDAENGVMVWTSVSEPVEGVVVPIHYDDDPSEATDPGLGHDSRFMSIDELARRRPGPISTACMCKREVVGCAVCGSPLGMRYTPCTSALRKIFPPPTHVPLSPIPPRTFVRPTPTSTARAPPVDPDAIRYRSRVADYLLAMTTPRATRSTPSAAPSPPDTIRLTPELHNEIEQGRRFGVSILPSRVPSWDHRNFSAMSRDQDSSSSTRIRENNHDDENMPGEPQTLQTMAHELADTETDTDNDSDDSQNDDHYRLPMITQTGPESAHLSGHWTNEASTRYIYRFFAEAVIPEKCSKASTESSGEAGCSSLIDWRKFYASLYGLGRRHDHEGHASIGDAGNRSPCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI38</accession>
    <name>A0ABQ8VI38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_920898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4488659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="50975" checksum="13FDA690EE3B4BE9" modified="2025-10-08" version="1">MPSSSPKATFSALSPPIHSCSSSRESVPLASEGEAEQDQLAFTIESPSRPQLQLFENIFNTGKSLASYCRDDPLWSTLAEVALPCSNCFKHPESCKVPEGSPRCSSCTGKKTCSLGKLLRHRYFSRRCSQDLAYSRRFLELHGSPAQRVSWSIPEDAWRRYDDRLHSNISSTSILLELNMLDDQDTQAVDRWELARFQWAQEQEAALAAKRKRTHVSPPREGSTKKRRSTKTRSQPGAPEAAGEVPRVVRLVFPPARPAPPPLFPSPLCPSSPDSVFAPRVAPVSRQTGSVWDPESLVQLAEVAGRQTSFASGSAAPLPMPPPLAIKGPREVPKAPSSPTMPPANRPALVPRVLAQHPYHAESERLITQVRLLESQLASLRQENSTLTSALRDTSTLLEAPYLPINPSSFPSGILLLPPASTPHPPVHPFLTRPNVPAMVDIFSDAPCASSAEARLSPSSLPILPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIF7</accession>
    <name>A0ABQ8VIF7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein yippee-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_763932</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the yippee family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="13"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU110713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="110" mass="12673" checksum="5EFE774837815CAF" modified="2025-10-08" version="1">MGMSYRRYLYGERVYGCSKCKTHLATIHSMISRAFNGQHGRAYLFDVVVNVVEGEACDRPMTTGNHTVRDIYCIKCGTTLGWKYDKAYEASQKYKEGKYILERNLLVDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIP6</accession>
    <name>A0ABQ8VIP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_918631</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045119">
        <property type="entry name" value="SUN1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911:SF8">
        <property type="entry name" value="KLAROID PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911">
        <property type="entry name" value="SAD1/UNC-84-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="7">
        <location>
            <begin position="158"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4495505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="358" mass="39513" checksum="BC016D0D3C77D3F3" modified="2025-10-08" version="1">MATEKLDYRRFVVADSSLRAQPPTSDPQLQSFPVVPTAPDTAQEDTSSDLSSRATFRSLLAPRISFQFCGSMVIALVSAIIGVYSSSLQSRFAPRFLFIACTILNLIWAVFMNEPFPRCDADGFHVFCGNCPMMSMTFSPHTAAGSCFEAPDFALGPDGAIVLALTSPTFFERLSPYEGHRSVQQDQFYAATPPLAVIEEDVRIGRCWKFAGGAGYVAIKMATPVHVTNISIHYPNHRELTPWRRQEVPKIIRLWALLPPEMDGSLVPHRSTSWELFDQTGLFVKPSALGEASTFIQGAIISYDVSKGTKQTFPADLPTQFLTTIVVVEVLDNWGSNVSTCLHRIAIHGEETWPEVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIR2</accession>
    <name>A0ABQ8VIR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_709888</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF23">
        <property type="entry name" value="ZINC FINGER PROTEIN 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="3"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4495529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="100" mass="11516" checksum="051AF9B8C8E21A0E" modified="2025-10-08" version="1" fragment="single">NTHVCEQLDCLKAFTRRSDLLRHMRIHTGERPFLCSHPGCGKTFIQRSALHVHSRVHTGEKPHCCEYPDCGKTFGDSSSLARHRRTHTGKRPYKCEDLQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIV5</accession>
    <name>A0ABQ8VIV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_947262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="313" mass="33727" checksum="3D66144AED66F438" modified="2025-10-08" version="1">MTAKPSMTAKPPTTAKLPTTAKPSMTAEPSMTVKPSMTAKPPTTAKPSMTAEPSMTAKPSMTTKLSTTAKPSTTAKPSMTAKPSTTAAEPLAVGKPADIEIIEISDSEPEVQQRTRKPVTKKPKSHQVNQVKANANPTSIKQGTTKKQSQNHLESIQISSDSDLGTASLVPQKRPREADSDSNSNDMASSPYVPAKKAPLRKMKVLKTAITSPPQVASSSKNRMSTTSPSSPSSDNFDRGLDQSFIDHAVALHLSVNVLHEQAQVVFDALSDKFGNGCPVNEYEKLKELLAHCEHCRWVYMKGIQHRCIPKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIY6</accession>
    <name>A0ABQ8VIY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ClpP/crotonase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_895204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4495595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="274" mass="30463" checksum="2F6A2DD89D076FA8" modified="2025-10-08" version="1">MSTLSVNISDRIATITLNRPKSYNAITVEDYDAFANALREIDRRDDVLVTVWQATGKWFCAGTDVMGRSLPNVGPQTDRPPTNSNNTLREMFLKRISHTTTDCGQALYSHSKVLVAALNGPVMAFLGYFDFIFSVPDSWLSVPFTFLGIISEGGSSVSFINRMGPARANEVLIWGKKKTAQELVACNFINEIFPSKSTEEFHADVRAHLQQQLEGLDPAAVLAVKKLLRAGLNEKNDPNAVNLRESYAQAERFASGVPEQRFGQIARKEIRHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIZ9</accession>
    <name>A0ABQ8VIZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">B30.2/SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_827374</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cclA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12872">
        <property type="entry name" value="SPRY_Ash2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037353">
        <property type="entry name" value="ASH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10598">
        <property type="entry name" value="SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10598:SF0">
        <property type="entry name" value="SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="5">
        <location>
            <begin position="106"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="443"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="588"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="704" mass="77917" checksum="4CB658D8636C864A" modified="2025-10-08" version="1">MLAEFSSPPPEARPSPQPTTAPSGNKKRKRGGGQQQQQQPAASPAPSDSGAPEVLTSRTDLFSRPQLKISRGPVFTPISEGSVYNKTDLIGVNRVGFRYVPAGIKTPSPSNPIIQFHTIESNPACYRVSWEDRSPFILVTKDGLGLLGSKGHRSARGNAPVREGKWYMEVKILKAGGEPSSNEGMREGCYVRLGWGRREAPLNGPVGLDGYSYGFRDKTGEKVTLSRPRPYGRPFASGDVIGMYISLPTPKREANQKDPTDPAHLKRERIAIDFKGQEMFEMQEYPQSKEMITLMDYEGKAANSTSVPSTTTRKGAGNRGGLAPPNTGNPVQNNKSKNPSTTSTTNNNLRPLPTLPNSRIAFFINGECQGAAFHDLYDFLQLRQSERKFKEKDKKKTRLREGLKESHKDNPFDDGSLGYYPFVSLFNDAEVRINPGPVFEYPPGEDIDALLDGTNDPDAIIPDTPTDPNPNPRPSTQTWRPLSSRYPEYMAEQWEFDEREELEAQENLAELDAQDRVVAQREKQKKTQRERKKKETEARKRTKVQPKDKNSVKEKSPSVGLAGGLGLLSQPQPSPLRHASVTAYEEYEEYGEFKDSPATYAAPGTPLETSLETPLDPPRDTLQDIIMETPLDTPPQDTPMEIQETPSSPAPVPDAVDTPGPYFDNGDNVQNEDDRGEEEEYIISELGNSTAGTEIVTEAVSEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ70</accession>
    <name>A0ABQ8VJ70_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_761943</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="639"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="682" mass="76833" checksum="1C2DBFDD867B5DBB" modified="2025-10-08" version="1">MPANRGRKKKGPNVKRSLQSDLARDVENARGWAEIVQIIRDQHQIPDLFTKAGLKRVYLNFDQVIRQLDSTFQKYEDNDEIVGGVVGIYTQMCEDAVLRTKLCENGLLSRLFPLLERDVCRQMALHTLVNIGHHGGTSVHAEVARQAPILVQTLLDHPEEHQTVEHIIVILSHSVGAAVNGDSQAPEMPEIHRSLDMRIILKTTIHHMRQLYASKTLIDHGNQLVFASAMHCSAAFRSEPDLDKFLVAGLKSKNWGLRGSCLGAMIRSYILSTVPDRPALGPAQLIQIFGSAWPPHLLEVMNQYGLSRCQSTQQRGHAMALSDAITGAHSRDHYILGGKLADLTLLTEFSLPATPMFPLSEIIPRCVEALRSRGTAADTNKADILEMKYLIKLQDWDGIKSKAQQFLARNPDSAYTFYALTLRPGSEDGLRAAKKGLKCKENNTTPYLYFQLLRRAIELAADLGVCYFQEYDQHGRMMWEEAIAFLMSALEDSKTFIEQAPPDNPYMMAILHWNIVLTITMEGPNADLKMVEVGLRSGARNKLKISEEISEHLRSPILHTQTYATQMLVVDLYAEAEKDWAAGIKLMDERLDEQIPPPDFPKKAEDELTAWLNDMSLKRFTCSSATPKVNVKDLWYKQCSWCRNPSAVLRKCSGCESARYCDSQCQKAHWSNHKKECKARIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJF8</accession>
    <name>A0ABQ8VJF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="425" mass="46024" checksum="4185BE96E22B1680" modified="2025-10-08" version="1" fragment="single">MCTAAPVSAGQSHWNRWCIQGVLTLFIDRDQDFHELPPFEGLNNLNADHLPFNALIQSSRFSEALMNFDFDHTLPGLDGPSALRVGAGSNLAATGEVANSFVPSSAQPTNPLFLSNEGLSMSPPFRDSLTPASPNPTHGPLPLSLQSVNLYPSLPNSPNGSPHLLSKPTNALSPSSFVTPPTPLLTSMSSSSTPHLVSMNLPPTPLPVPLNSSPSTSFNDPSAALNRAAANPLLFSRQPTTHAERNPLLPTQTIRARAARHLDAVQSRTMHEAKVEKQKLDSLLKQDIIKLMTTFEEMTASLAHKHHRTPAYVKELISTTSHLSPQRATGRMQALIHIKSKEVNSTLPVGSKLKAPALRKLVDEDVELLALSNEKVQEAQKEVDVKRLLSTRGIRPTNAFAGRDFAATSGLVKTEVLVKTEDYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJH7</accession>
    <name>A0ABQ8VJH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="201" mass="22363" checksum="7282E35EA36296ED" modified="2025-10-08" version="1">MIPTYLPKTNFIPSTSPFFTKLHWDQFAIRQEGPRSIGPLLWTSGTPPSVSPEHTGQFARLSFHGRSFQPVLISPGAPLKRPAGPRAMPKRPTQAQDLSTTSQEPGTVQWCIPALQTVHKNIPICLQVSRVRLSDPPPRRKPPWIASFHQGCVFAHSQVSRIALLDPPPRQKPPWIAPSPSHQSSSDDAPELEDDHDLMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJP7</accession>
    <name>A0ABQ8VJP7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="62"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="194" mass="19993" checksum="F3ED42D03BBFEAE8" modified="2025-10-08" version="1">MFKSAALAVFTALSIQNTSFSSSSGPFALSWNSTSPYGQSSGLFAMFDGTYGSAMNFTSGTPSSSNLTASYNATSGKLSLVCAGDDYLTGLVAALVYEPELTPPTYTLQWVDDSDATLPAGSNKTSLVPMDGGIVSTLGSGIFKEVIVDDIVSGQNVTAFAWVQETTAENQDVQAHIVIADGSNVTCAASTSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK38</accession>
    <name>A0ABQ8VK38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_918321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="50"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="620" mass="69977" checksum="451CDC9117E86F77" modified="2025-10-08" version="1">MAYTDTADSGRVGDSAISPTRLSLKRISSCKLTPTRRRLEDVIPRSHDHRTLVLCFDGTGDQFDEDDLKNSNVVNLFSLLKKDDPSQQLVYYQSGIGTYTIPQIAQPWMAKLHKAADMMVGIHLDAHVMTGYEFLMQNYKIGDKICIFGFSRGAYTARALAGMIHKVGLLPRHNHQQVPFAYKMYTREDETGWRLSTAFKKSFSIDVDIDFMGLWWISLLYLSCALLRAAMLRDTVGSVGVIPKRLPFTSSNISVRCFRHALSLDEHRARFIPSLWDHSLPNRQFKKKHLGLSFGLPRSLRPKSKKLFGNSQHPEQNGTVMEVESQLYRAPNNGSSQSTNNGPAHRSLSQLEREYDVMIGLDADPDVVDQTPTNVQEVWFAGCHCDIGGGAVKNDTRNSLARIPLRWMIRECFKVGTGIMFHEEMLKQVGLDPGSLWPHIRERPPHATASLDDQDRYTSIAGPSSNTLSNSEGQHSANLADFITEEYEDEMDALSPMNDVLKTDPGWWVLEMLPYKVKYQRKQSNDSDEDDSHYSSMGRRESDSGSSSSGKWASKISWANLGRARHIPRNVQGGIKVHRTVKIRMDADVVALVDSKGKVKGKGKKYIPRPKWDFDPVWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKA6</accession>
    <name>A0ABQ8VKA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein 14 C-terminal Fig4p binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_248336</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="6">
        <location>
            <begin position="669"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="438"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="888"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="473"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="889"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="923"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="970"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4496813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="980" mass="108950" checksum="53795E382090A1E3" modified="2025-10-08" version="1">MDSAVSKQLVDKIYEKRKAAALELEKQIRECHQQGDDRRISLIIDQLVDMFSNPNNALHVRNGGLIGLAGTAIALGVDVAPYMDKFVYPVLDCFVDPENRIRYFSAECLYNIAKVSKGEVLIYFNEIFDALSKLAADSELSVKNGAELLDRLLKDIVAESASVYIPIHAESEKPYNESQGVLVPHPVDPCSAKKAFSLAHFIPLLRERIYVVSPFTRSYLVSWITVLDSVPELELISYLPEFLEGLLKYLSDPTEDVRVATEVLLADFLREIRDVTVVRRRSEKLAKSTHTVGDTESIVPSEGGQTEHSITDSPERAVFLADHDDAQYPDSEYKEDRASDFDVRDAGSWVPGQGVKIDFPSIVEILIEQLDGEPDDEIQQSTALRWLAEFINFASEVMIPFTPRLIPAILPNLAHHASMIQTIAVRTNKLLLSVIQNLPSPPEVPARSQEKPPSTRVQASPTPTAIPAPTSSNSRQPTMAKDSSTSLRDAASPETAGDAVSPPPMNANSSSSSGVSLVRPRGSGVDLSMTPRTIVAETLPQPSTSRPQSPVSVLSHSNQNLQASITEEPDVFDYQATVNELTIQFLSEFEETRVAALKWLIMLHQKAPRKILAMDDGTFPALLKTLSDSSEEVIKHDLQLLAQISSSSEENYFKAFMMNLLELFSTDRRLLETRGSLIIRQLCLNLNTERIYKAFAEILEKEDDLEFASVIVQKLNMILITSPELADFRKRLKSLETRQDGQALFTTLYRSWCHNAVAVFSLCLLAQAYEHASNLLYIFADLEITVPMLVQIDKLVQLIESPVFTYLRLQLLEPDRYPHLFKCLYGLLMLLPQSSAFVSLRNRLNAVNSAGFLHIAPKPTVGPLSGRSKLARDEIKWQELLQHFRSVQSKHEKARRQSDQSERVGRSPVNGRPAIRRKVTGDLSVSVNNTSSSGPLSRAPILSPLNPRARGSSGATPMNPAAAITQQAQKGRRTISLTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL01</accession>
    <name>A0ABQ8VL01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endo-1,6-alpha-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_760827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127070" evidence="1">
        <location>
            <begin position="18"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="411" mass="44086" checksum="43AFD3ECBC6A7633" modified="2025-10-08" version="1">MFPFAISLFLTPSLVFAQDLGVPLTWREFSNSRLLAERISIAEDAINTILPQLDTSNAQFNGIGYWQSGNVFSAMANFDHLAGTTTYETQVINGLNTAFSLYSNFDQYGSLKPAGGGLQLHTTVTEHTEMKTCCQWQSLPGLMFHSSKSDISSGTAWSQLALSVISTADASSGTQPNKDFPIAGTCFGESMAGGVFWRPTVDDTGINSITTGFYQPRLSAFLAETTGDTTYTNAAILSAEWIQNLQINADGIVLDTVDGADCTRSPATWLFTYNSGKYLEGLSVLKDVTGNSAWTTLMTDIAAVAIKSSAWEGSNGIITEGASPTANNDGVGFKAIFIRGLDEVSVRSSDNSALQILIHSYNDVQYNALLELADNGTSYSSSWTGPPQEFTTWGQLAALDVMVTAINTNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM22</accession>
    <name>A0ABQ8VM22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_894635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="523"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="846" mass="95104" checksum="0C3F939F3E4E820A" modified="2025-10-08" version="1">MSEHPTTSWQAMQNGTVFYRRQQLYSILGKLPDLGDYIIAGCRYGGPLAMMRDNTKLIAVGRVTPAHAKFQIQVYSSAGEGLLLFSWDHGRIIRFGWTLNEQLVVLNEEGVYRVYDLQGEYQQYSLGTEASEVGIVDARIYENGMVALTGSLTLLEVKGWEGARPMNLANPNLTDPPMSWAIIPPDSNISRHVEVLLSVENTIYTVDNLESVDQRLSQGPFTHISPSPNGKSLALLNASGTLLVISSDFQRRMAEFDTLNVPSAQGNVKQVEWCGNDAIVVTWDSLAVLVGPFADTLQYYYVGNTFAITETDGIRILGADVCDLIQKVPSSTLSIFRPGSTSPAAILYDAWESFSQRSPKSDESIRSIRPELATAVDGCIDAAGQEWEPYWQRRLLSAAKFGQGFLDLYDPTDFINMGQTLKVLNAVRFYEIGIPLTYAQYSYTSPTHLISRLTSRNMHLLALRISTFLSLKPDVVLKHWASAKIMRTRPVASGTGKDAELDSDEEVCRLIVDKFKQLGDVEVSYAEIAKRAWEVGRTGLATKLLDHEKRASDQVPLLLSMKEDRLALQKAVDSGDTDLVYQVLLHLHKHLTLGSFFRLIEDGGEQLAPASRLLQVYAREQDRDMLRDFYYSDDRRVESAVLALEEALHMVDPSARIAAVKSAQKFFSEDKDRNFEAKMTDEYSRLLTLQQQLEAEADGKVAFFGQSVNETIRTCIINGMLKRADKVKSDFKVPDKRFWYTKLYALTEVRDFEGLDAFSKSKRSPIGYESFVRHLVEKGHSKEAVAYVARCDPPKRADLYAECDEWRMVGKECKDRGDKAKLEQLRKKCPNSLIARELEQIAISMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM81</accession>
    <name>A0ABQ8VM81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavonol synthase/flavanone 3-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_822426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="183"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="337" mass="37493" checksum="7CB309C5CA2102E2" modified="2025-10-08" version="1">MAINRESLPTVNFADFGDGTSKSALDIGKKLFEACRDVGFAYLINTGIPQGQIDGMFDWSAKLFALPIETKLKAPHPPEGWKHRGYSGIGREQVSQLVFDPDELRAIRTGKFPDFKESFDLGSKDSQTLPNTWIPDEDLPGFQTYATNFYNTCREFQLSILLPALALGLDLPKDFFLGYHEANENQLRLLHYPGAPTSVFESGERGRIGAHTDFGTGTLLFQDDCGGLEVETPSQPGVFMHVPPVPGTVLFNIGDFLMRWSNDTLKSTLHRVRAPPRRDGHGDDGETKERFSIAYFLGADKEKTIECLPGCSGPDKSKKYEPIKAGEYINMRLNATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMA0</accession>
    <name>A0ABQ8VMA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046930495" evidence="1">
        <location>
            <begin position="21"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="145" mass="15204" checksum="E0402E6B4F885A13" modified="2025-10-08" version="1">MRVSSVFVCLFFGIVSTVCAAPLPVHVVSQLRRSDPPRVTVNFIDNSQGSLVSMQSTDFLAVAQSLLDQHATDLGLGSNFVILAENVPTKQQANLLFTLVGGTKCMPTLPCNVAFGTGSGDGGPISVTVTSRGDTIFTGDVTVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMZ4</accession>
    <name>A0ABQ8VMZ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="243" mass="26992" checksum="FC8B91396D4C428E" modified="2025-10-08" version="1">MSRQRAAQQSVGNEPVSSNSINIPSNSNLRETRSQKRKSTATVADNSLDTEQNPSQQSTKRTRRQKKDSTLRSTPVAPTPQPSQRRKPHQTRASVQSQPKHAPLALQHTPKTPMLNPRRHEMTNTPSNLCRSPALLTANTFKPNTHAAPGARLSMNTTRMTRRGGPVLIPSDDEDADHPFSNQSQIRQEYKNAQEDDSNGESDPNLDFKDAEMFNRDFTVGTIGAALNQHGSDDIERSLSSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN22</accession>
    <name>A0ABQ8VN22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein C</fullName>
            <shortName evidence="8">U1 snRNP C</shortName>
            <shortName evidence="8">U1-C</shortName>
            <shortName evidence="8">U1C</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_901390</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the U1 small nuclear ribonucleoprotein C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="97"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="97"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="203" mass="20577" checksum="8E9268212AD569AD" modified="2025-10-08" version="1">MPKHYCDYCDVFLTHDSASVRKAHNSGRNHLSNVKDYYASLGHDKAQNIIDQITSAYESSGGPPPGGFGFGPQHLGAPPPPQFPMQFGGPPGMFGGPRPPFPPGGPGFPMPPGGAPPFPPNGGMPPPGMGVPGMPPPGFGAPPPFPPNGPPGGAMPPFPPAGALSGTPPFNGPPPTQGSLPPGPPTLGSGPSIHPDRLRMMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN74</accession>
    <name>A0ABQ8VN74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS, DHA1 sub-family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_758834</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF31">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="8"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="466" mass="50328" checksum="017AD053FA90EC21" modified="2025-10-08" version="1">MAKVETIVFLSLVLDLFAFTIPLPLFPRLIEWYTTREISNSNGFLSQTLRFVSAIRALFYKPSLHSQKWDIVLLGGLMGSVFSLLQFIVSPRIGSLSDKHGRRKVLLFTMIGNILSALVWIKSTTFASYMLSRVIGGLSEGNVQLAIAILSDVTTPENRSKALAHVGIAFAICFCIGPPIGAYFASKPLPAANTFGIEFNIYAVPAIITLILLSVETVFLIVALPETRGKGIKPVENKSKSNGKSTNGATIPKSKTIEQRIEILQSLRTLHLLFLGIFSGVEFTLTFLTFDLFDWDNKQNGMLIGSIGIISALLQGGYVRRATSKIGEGVMARRGVSSCALALVFLAILPIYVSTNLTLALRLLQLGAVCMAFTSATVVTSLTAFASLQCDEGGFDITTGKPVKVHPQLAKGKALGKFRSSGQLGRAIGPLIACASYWTVGPIYTYATGAVAMFALSMHMRKIAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN96</accession>
    <name>A0ABQ8VN96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase family M48-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_215739</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07331">
        <property type="entry name" value="M48C_Oma1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051156">
        <property type="entry name" value="Mito/Outer_Membr_Metalloprot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726:SF1">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M48" evidence="7">
        <location>
            <begin position="191"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="411" mass="45287" checksum="27A9F4A0536C2944" modified="2025-10-08" version="1">MLRCIWDRNFRPSLLRNLGVRYSLNTYYFHSSTFRQASPRPRYVRFSSPNPNPGPGRGNGRKFFGDRAWPMKVGAGLAGVGVICYVSCLEQVPETGRWRFISISPKAEVQVGQFALQQTLAQFQGRILPDEHPVTMQVKRVVQTVLDASHLGAVRGYSQPHQQFSSNDFANDDTWSSSSSSSSIKSSPAAIASAGKEWTVIVVDERKIVNAAATPGAVIVFTGILPICKDEQGLAAVLSHEIGHVVARHAAERLSSQTIATALTLFLSALGLDFGISALLNKFLLELPNSRLQEREADLIGLRLMSKACYDPKASPAMFARLGQLQSQASRGGFSSPEFFNTHPSSESRVREIESHLGEAYALIAANPACAELQERVQAFKESARLKNAFDLGPRLGRNHDHIHDEEEVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPB3</accession>
    <name>A0ABQ8VPB3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_791077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="426" mass="47441" checksum="3D003163C937890B" modified="2025-10-08" version="1">MDNRVFAVIVGIDQYKSGDIWNLEACVDDAKSMKRWLVNDLGVPKHQIAMLVNEKATKQNIETTLNTHLLNNSRIRKGDAILIYFAGHGSTLKAPRDWLLEKNLRCNVEVLCTYDHDTKGPDGRIAGISARAMHTFIHDLSKLKGNNVTLMLDSCFTSPPPSSRDRSCIRWTATGKAVAEDLYRGQLPCPRLQKRNESFYNRHWTTHTVITACRPGASAFEGKEGGKLTSVFLETVRSVALHDTSFSDFLEEIKRRMGEGQSIYCSGVHPARLFNSIPFTQDHSYIPVQFHLQKGIRIELGSLHGIEKGGEFSIHGHNCVGSRNPVLASFTVQQVYPTWCVGKTKTSSLLPKHCWARVPRNPSSYRLIKAFRALLHSAALHKPLAASRSVSIVSISDIKNSTTKSELIETAEAILASKPLLAPLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPU3</accession>
    <name>A0ABQ8VPU3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_733197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="26226" checksum="5E4D0DADB42FC235" modified="2025-10-08" version="1" fragment="single">MLQGSDLEGYQIPHAIEKLIANLFADDTTTFLAAEDDFMVLQDILNTWCLALGTKFNIPKTQIIPIGTENYQKEVIRTRKTKPDKTPLPGHLRIANEGEATHILGAWFGNKIDAEQIWAPIEWWDVNGLTMEGRRHAIQMTVGGMTQYLTCVQGMPKSIEKRLMKCIKIFMWNGKERSPVNENILHGPLEKGGRKVLDIQARNEAIDIMRLKAYLSFNTLWGGVVDALLAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQ62</accession>
    <name>A0ABQ8VQ62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_758749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="34061" checksum="8FDE674F50D955ED" modified="2025-10-08" version="1">MIYRTNTTLTLIELCKSTISNEISLLAVWCLLRICRSPEVAQGLIKTNIVSVLLRQNAIGDMHLISMSVYCLGTVVQNDATADFLAAMDIIPFIVSHLRQSTESPRQNPDHICAGLYAVARMSRSIKLAKYLAKAGCVELIVHHLNTSTDPNVLHWSARAVGCLMRPNSSDMARILLEADVAKGLARLPTVLTSENLQALGSLGFTVQRFSCAEWSGKIRQTLVEAGVVDSLLAALRTAADEPCHDVHIELALAISLLGDVGGSAIRKEIVNAGGITILKSVANGNPEVAKACNMAITSVTGNIWSRNAGSYIDNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQM7</accession>
    <name>A0ABQ8VQM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED17</name>
        <name evidence="9" type="ORF">C8R41DRAFT_893957</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10156">
        <property type="entry name" value="Med17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="665" mass="73725" checksum="EB863CC2346FEFF1" modified="2025-10-08" version="1">MEPGWKQTKLSLERPYKNDNGEVIPVLYDITSDGILHYEHKETPTEVLGRNLQRIYEERGLEFFELLKDGSLQTGVLPSVDAADKREDETQDTAFDEESNHTMTKDELYKLKMEVMPQLYIALGEMTLARDLLSSILASSNGLSTALPSILHSIAAPEPQTQQPESLPPLSATVVTKPPSIVSVQAFNAQLAIGGKDEALRKAAHLFKSVATRMERGRLQNERYWVDALKIRRGNWGLVPAPLPPGSAIGKGADKTSKDFIISYGLEECLSSSFHHSAPPILRRSAIAHMSYGGSEEESLILPQRFNIRLRVSIGSPDASGNIVYSHNALEVSPEDHALSLDERLKDAQRAVIEQEIFSILVHEAGTFPTASARVSERLVLVDVTQGMELKFELVDAGIFSLGMSSTQNPVNQAKSDFIYHYLLTLLLRRHAYVKARRLGTDSSSSLSISSLDTSQANLPILQPVIDQLQYQIFCERIHSQLNVVKAALIAAGIPSTLRFNAVGEIGSELIKIPVDEEARPLSGVCTLRIDNRHNLRLTLASPSALTAHLSQATISISSMPQLCELLSDEVERFFLERICDVGRRICNDMGAVWFVDLNRCVGRWEGCVLNFQITFGHKFKIICIATRLSRTDPKHPVVDTYDSSNAEKSLIDWVQHVLGNALNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR00</accession>
    <name>A0ABQ8VR00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_244194</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051653">
        <property type="entry name" value="E3_ligase_sorting_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168:SF1">
        <property type="entry name" value="OS02G0798600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168">
        <property type="entry name" value="RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="1042"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="122"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="348"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="479"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="548"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="615"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="674"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="815"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="885"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="479"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="502"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="554"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="572"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="676"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="700"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="712"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="737"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="837"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="900"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="917"/>
            <end position="941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1097" mass="115757" checksum="0A54418AAC782FB4" modified="2025-10-08" version="1">MGQSQSDSNDSRIRRVQTNPLSADILSAGGSTDGRRFSTRPQLTPSSETTVRSFSLTRRRKAVQKRLSSIVKPKLELEATSSRARVNEGSQLARTDIPEASGHRSAWRRSLRFVKSRRWNKVSDHNKDDGGERISISNSDATLPISISPPQSSSFNSTVSIPACSSDSATTSQPPETSVPNPDTAILGSADIPTILTPALSVPPFSGEESNTNPLAIPSESIAALSTPHAAGEMETTDQIAVATAENPIVVASNANSGAISENVTVLLEPNSTSTATTTVPVSPARPQFPPSGTLVVVQGVVHTSDVQMSTETSAPFLSQTQNYNPNPTPPSSVIAEAPQTTDDFRTVQRVPSSVSSGHRGRLSALLRRTHRSPSSSRARSVSSALDSSSTHSANEASADIRQSQTSDAADVQSSTLYPPSPSPPVIQRGNPSGTISSSSIDVLGTLLSVAAAATAASLLTGSSDSASSTGLAYPSLVTTGTPSSTSIPGANTPALGVPSSLEFSSPYPSTSRRPLSTQINTTNTESVGARDRAERISQLWSAVRSRLGIGHGQPSSQRTDPDSQPFTNPIDSDASADAAAVDARGGPGAGPVMDAHNARERMLNEISRAFNLGFSSPSSSAPPTNFTTDAGDTSQGPTIGRAERGNSDSGLPSEGTFERFLLDLQVDLRNVLTGEGDRRTTREREEPTIPEANNSLTSQDERLPRPLREPEPEDDTEEDSIPSLQDVSDSDDDTESNNSHASSSDSFASVSPADEAAQHRFDVSESPNDPSIPRPRINYWRLHRFPPIPAARAHAAADNVAQNMRSGLGGLTRAATLGSTPAPRSVTSIAGEDSGTGATPSLSRNSVVQDSPNTGSANVVPVVIVGLQSVSPFWATEPITTPRNLMNQSPVPSRADNAIRSTPTPTTGTMLQDTGSSASSSTSPVGMTSQGTQTQTSNTTPRDIGIPIPSPDSRTFLIYVIGGYYPPDHEIVTGTGENGVLDSSFEALLLLNELLHRAPFETPITVTKEQLNKSGLEIINGGQMQEWVKAGKVRSNCVEQCLICLEEYDKQDSVRVLECKHAFHMDCVDRWLLEGRNSCPACRGKGVSEGSEARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR02</accession>
    <name>A0ABQ8VR02_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_755842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="34926" checksum="2D100C6E24C1FBE6" modified="2025-10-08" version="1">MVGKKEWKVTDIPDLSGRVAIVTGGNTGLGYITVRELARNGARVYMLSRTESRALAAIEKIKTELGSELNPEIEYINFNLSSLKSAKKSAEEYMQREQRLDILVNNAGIMATPYELGPDGIEMQACNGTGHFALTVSLLSILKDTAAMPGSHVRIVNITSGGYMFANFTKPDFTSLEGLNQKTFGTWGRYGLSKLTNILLTNELQKRFAAAGITNIYCLAVHPGAVNTELSRGLLESWPFLAPLRRIGRMMTMNPDRGALTQLYAATSPEVEEKDLKATLLFPIAQVEGKASIAKDKDGKLGRDFWRLCEELMRQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR12</accession>
    <name>A0ABQ8VR12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_816494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="2">
        <location>
            <begin position="192"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="335" mass="38004" checksum="8BEDBDF026E82FBB" modified="2025-10-08" version="1">MPSIVVTRASPTTIVPHSSGHSSHSSLSSASTQDGTKEYRVELEERRRRTVFVTSSVPPEQWETREILDIANIEEENEKIFEGDFSATVHRNSTRSRSAQDLPSNDKTQHRHSPQTSSRYQSRRASLKPSDALSSAAATLNRMSVMPNTPPNSPAVWKPNHSIARTNLSPNAHGPRPTTMAVAIAPRPQVLFYHKHHPHYGFTNFSPHPVIYKGKRYPSSEHLFQSFKFHGHRPLIAEHIRTCGERPSIAFSEARRFQSEVRPDWKKINVEKMDVALYHKFTQHPDLMNELLATGNAELVEDSDKDAFWGIGADHRGRNELGKALERLREQFRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR71</accession>
    <name>A0ABQ8VR71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_915997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="29082" checksum="5F454D19C25A58B1" modified="2025-10-08" version="1">MNRYTLVGLGLAGDPVPPLNITMGGLAGIGHEDVHIIINDSAGGADGVGTMGNIGMIMGLGGVFFCAFTSAATRGKEKERVDDKYPIASSSSSRTTASPTCGKECESTAWSEDHRFWCSAKDADDETTAAPASASTVNAGEPSQMPQHQHAANAGEPDRRGKKGIVKEIGMAGTEQSGASTSRARSPRKARGFTLFNLQRSSLGQVVPSQSRARSELTLYGSSDGWEFDASEGGRTCFETVTRVMSVGSSTGRPDLMIPPYVPNSTQFRTRTIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRN4</accession>
    <name>A0ABQ8VRN4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'-5' exonuclease</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Werner Syndrome-like exonuclease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_915699</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="11">
        <location>
            <begin position="46"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="344"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="503"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="526" mass="58357" checksum="617BF1A05FD17F26" modified="2025-10-08" version="1">MSSYSHPVGPGSLSTSSMTPYYLKDEPQASNTLRHMANSLNAAAYEFFRSPENFVPPHIGFDLEWKPNYRPGEAENPIAVIQIAFQTASYVVHVRWMRNLPDGLAEILENPRIVKVGVGIQNDAKKLFKDLRICLNSCVDLSLFVKCVDSGLFAERLDRYAGIPLPSSAFTPPSLPPDSTSPWEFYASETFLGPHFRRLFRGSYFSSIGLARLAETYEGIVLTKGKITQSNWDLELSPAQLTYAALDAYAGSVVYTHLIRLFSLLEPTKRPKRKFYAFDCIRGTLYNCCGDDRRTLLGEQMEDTELPRGYTILPTFYPVEDEITLHLQGVGTDQPRGLIVWNPSNPEYDPGPMPPKKTPEEKEEARIARQKRRQEKMKEEVAQKGGAKTMKEEAAQKGGAKTDSEVVRAPNDSVSVAPNVARAPPRIDNTGSRAQRRTNFVPKNINNHGPTNLVGSSALPRNPALPITSSGPNGIHSSMQTARISNAPSSKAPGAPTEGSKPHPPRRPRYRKRNPPPQSTNQEVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRN5</accession>
    <name>A0ABQ8VRN5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_915657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4498997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="804" mass="87635" checksum="1D356CC599113323" modified="2025-10-08" version="1">MASPINIASSGGTVEKNSPTQAESDNSARSRTVMTMLSGFANECMTEWGFYPGMTQELVTLKVENVALRSENTALRAGNAALRNTQSSMEASMKKLWQDNEILDRTLKSIGPERDFFKDRADRYHALFAASPEALPAVCRDLQQEVERLRRQYAALTSTTERLVNDGLALGVLVKTDNSPDDMSLNVHYQRPHLNTTQARTVPSNVAQNTNGATIHQQQPYVNNRSPIISNINHSSTGSIHIPSQTTSQPHTVAHRTSNDSSKVMSHADHRRNSAPSISPIAHERPVASVSMPAQLLQSQYNANAPQSNRVSAQVGIHSYSQPQPSTICPYPSRTITHPKPSASSPHPFTQVQMISQGHSTPFENHSSRSSIPQSHSVPSKIQPTQLRMNPQSHSALLDNQSSRSSVPQNHSVPSHNRLSQSPMIPQEHPAPIETHASRSSTPHSYPVPSNNQSVRSCVSSTQVSPSQNAQNTRFSNNVYQSNPSTVPQSASRMGPPSTVVYHTPVPVSSCSGVHISAQVHDAQPDDKKPIQGPAPPTPPQSDKSLSPEQEQYPTLPSPLLIRTPLKRVSIDEGIPPSPSKRMRLDGKEAATPVHSTEAPTVTQSVESMVQDDVPSPHFDQPVTGNVIVQSPNLKFVGTTVTTMEKDELVSTSHALASIEPDLENLEIPQSNLMSNNPSDPVISDVGSRQMVNNAEAEGSEDDEAGRDKGNKEDEDEDEDEEDEDESSCTEKEALEEVLKLGHSGNICKLCRARHDRYPDKYTDAIFDCNTPTSVLVSHFTTVHPAVWTRLRGSSVATPTPTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS92</accession>
    <name>A0ABQ8VS92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_755073</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="9">
        <location>
            <begin position="103"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="367" mass="40923" checksum="96289F2C125D2011" modified="2025-10-08" version="1">MAKSKGGYYAVKKGRVAGIYTTWRCEEQVKGYPGAKYQKFVSKAQAEDYMGSVEVSSETVQPVRASNDTDSKSKPFKSIPSKGKKRTFAEMQTPLLIFEINDSVEPLVVYCDGACKGNGKVGSVAGIGVWWGHNDSRNLAERCPGEQTNNRAELIAICRVLETTRFQKGPLTIKTDSKYSFNDWLQKWLENNWRKADGSAVKNPELIHYVAILLSSRFRIGQSVKLEYVKGHSGIEGNEGADHLANLGAMMDEEDDRDWSALRNEYTTTLEKMIEERKSRQAAKNQAGSLEVIGVEQATRDLEKEPEIEAVNTMTKGAPSINETKVRRVGDEAEVNVKDEHIHKLPVVSFYGSRRYSAGIAEPSEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSE0</accession>
    <name>A0ABQ8VSE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="363" mass="40804" checksum="747B95140B5EF8AD" modified="2025-10-08" version="1">MSFSVTINRIGSGRRRQSRTSTASAQCSPMFMQIAEHNDTGLLRDLFIEFKQHAKKRKLVTFDKRTMKWMPWNPPIEQSQSGQTTTVCPMEYTNILGYEGPLCPHISNGFFTDDDCTMVVRTYHSHGETQYYFLAPHVGCEFRMKILWSANLSLDFGRGVHWDETVADISFTYLSNRQWSNLSSSSTREIEHLLQHNSSSSIQTIISPSSTDHCISNTIDSSVNSSYASLTMGLSVGTVTQSQVLPSTTTENAPETFESFYEEDSARARASPDLHMVQVLRDAFHDGVFRKYPSLHPTYNDDNPPSILQSFDPRSTPGTSTFSHLQYFDTVVGKVETAMVVDANFHPMVTQVTCSKPIRNTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSI6</accession>
    <name>A0ABQ8VSI6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_815351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="1">
        <location>
            <begin position="114"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="258" mass="29336" checksum="E067EAA09049A2D9" modified="2025-10-08" version="1">MTLMRRRYLPDIISVMTCTVCSQKLDSFSTGYKNTRIYHAIQRSEVPRRGSEYSPLPTHTAALLKSSSPAYSVASLPVIDGSVSPQPIPTIMLPAVDCQLHRALQSNKFSPSAISWDMSYPVETARLQPPCTQFDWNAPATNPHTTHLTITFGAWKFTVVPHPASRVSYVTVLDVLHGIYRYFRTSSSERDYRALSSDKRHRVTSAYNQRWQRCHPAEQEMEQKKGVKQIDFLADSKTFWGLLPTKELGTWQLQVTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSY0</accession>
    <name>A0ABQ8VSY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_24954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF15">
        <property type="entry name" value="SEDOHEPTULOSE 1,7-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="234" mass="26855" checksum="A2F53B9075D19326" modified="2025-10-08" version="1">MPRPMPRLFVIRHGETEWSLNGRHVGISTLFMYALHETTQTGRTDIPLTARGEQQVKEKAPILVGEGRPIDPKNLCTVFVSPRQRAHKTFHLLFGHVETPNHILTEEAREWDYGEYEGLLSSEIKEKRPNWNIWLDGCPGGESVEQMENRVDRIIDSVRKYHREYHEEGLNTRDVVIVAHGHLSRVLISRWIQFPLKLGTHFNVEPGGVAVLSYNHNTLAEPALNALNLYADLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTB2</accession>
    <name>A0ABQ8VTB2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_29050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="739" mass="82339" checksum="6EE5EFD9A3CF2EB5" modified="2025-10-08" version="1">MEYPPDHTSTLRAPAGTKQHRLVGRAQQLSLTFIMHGDVRKEQLIAPDVNARLVQFMTEQDLIYVERDGSPAVFNEDGLNWTVLYCQHSHRAGGSPILRHHPTPWQLNYWDLIQSAKRYSAVQVGESETELLVFLGFLPGQAPCVHRHLCLHFRLWAGFSSANEEDLVNIDNILREACWINRDGEATTGHIPGNCPLHESNLPARILNTVVALQASGPVSTSGTLLPSMSPESSNINHAVEANRDDSSSSATSTPFSVTSLLPSVSPEPEHQLNAEPEAELQPSLYHSYESIIADAQHFHRISPDVYGPQASVFNALAGTPPHPASARGPNVEAIANAMWDRFIALANGDHSLEESTESQGVTLHNFTMEGLHSNLVLMSIISGDQGAMGRGVWTEVLHLIEHKIIMDDENWQQLGFDGYFTLKLRDFEDIPYPTTDIRHFRAVGLFLRLALMWQVEPVAISPMMVAYLISESMEASISLNLLSRVAPDLNHRISQWPPTAHESITFISVPFQLVSQAFSDNYTVAQLRGLSTQQINTLTPKIREAIAFNTRPRQFQVAHPLVKAITEGINITHHHNTSSLYSTVFDSEPEQLQDYLISAWTGRHIQSWQDVVRLFDIQYIESAGREYLARERGFMAGLLRFLQKSVFNCRLFLVAVTGSPYVPVAVSGSPSKFHISFRTYLAHGASASFHSCSKQVDILHSEETSTMFLSSLPDNLEESTLFDSWLLALIGDGDFNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUH0</accession>
    <name>A0ABQ8VUH0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_813021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF15">
        <property type="entry name" value="TRANSCRIPTION FACTOR MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="269"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="388"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="109"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="737" mass="81720" checksum="F80C5B8BF8D59E1F" modified="2025-10-08" version="1">MPPDPQIFKATYSGIPVYEMMCKGVAVMRRRSDAWLNATQILKVAGFDKPQRTRVLEREVQKGEHEKVQGGYGKYQGTWIPLERGFSLAKQYNCDTLLRPLIDFQPAAKSPPLAPKHLVSATAPRPARRTATGDGPGGSVVNTRSSRRQAHQEVDQASEGQETLSVVGTEDGSMTPSPSEASSSSRTPSPINSPGPYSLNTVGSARQRRKSIDDRYNEYEDEIPVDGINDARAYGDQILEYFISDTNQVPAILIHPPIDFDPNMAIDDDGHTSLHWACAMGRLRIVKLLLTAGADIFKVNKAGQTPLMRSVMFANNYDVRKFPELYELLHRSTLNIDNYNRTVFHHVVDVAMSKGKTHAARYYMETILTRLAEYPKELADVINFQDEDGETALTMAARCRSKRLVKLLIDHGADPKIVNNDGKSTEDYILEDERFRSSPVPPSRAMTMSFRNAQVAFLPPNAPPNYSFGPSNGDRPPLHHSVAGQRASTRCVNDMTSMLDSLAASFDQELRDKERDTTQAHALLSNIQGEILESQRAVGHLQRVAEGMGHTKQSLSALEKELNDRMCRRYRMGCEKWVKDEEGREMKIRDASGGVLELTPDTATFIINGGPSSEDPLLNNDDGTASKRQVGIQIDETVSDLLVLHDNIPTDPEALKRACDGLREELGAHRKRRKVIFDELVEFQAEAGTKGRMKDYRRLIGAGCGGIPPSEVDGVLGMLLETLESEEPSGKSNTSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUH7</accession>
    <name>A0ABQ8VUH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_812856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="47267" checksum="14205AD58E01F215" modified="2025-10-08" version="1" fragment="single">KSWVMLFGLLPHPLPQFTLSGETLTFRDVVRYVGVFFQSTHRNIFASHYTKKRDCAVGTARAITGCDLLIGNRRMPPAITKQLYTALVDCHLTNGCEITPDTDPSLLRLLEDVQTRFLRRMLGLSSNSVITPLHTETGIMPIRTRRVSLTLRYLKYLMDLPDYHYASLALNESNNLRNSQSPCWLSDLDYAINQLPGNHRLPNLRSLNGDYIDRLIKSIEFSTKADLQSHIDMWSELSLLRHRLEPNEEGPPKPLLIGLRHYLTRIANHKHHRVITKLLCGDYIPHVFRASPSPLRQLSTAERFSRLCRACNLQPETPQHVLLQCPSLNSVSFLRSEFMSDIRQSRPLPINTFLSDSTALHYLKLLIFDWSLIIPTAKFIHDAIGRWQHFLDTGIDLHLEDDVGTGGEDSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV91</accession>
    <name>A0ABQ8VV91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Triose-phosphate transporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_752212</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="57"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="420" mass="47288" checksum="04456AE59870B3B2" modified="2025-10-08" version="1">MALLRQDDRSLDDSLRRSSSQEDDYEQQDLRPSFYAHVPSVEEKRRLWIQNATVNTMFIGSWFFFAILLSMYNKWMFSDSHFNFPYPLFVTSLHMVVQFILAGLVISIWPHKFRPDRYPTTEEYGKNAVPTGATTSLDIGLSNLSLKTVSLSFYTMVKSSSLIFVLLFAFLFHLERFSWRLVGVIMLICSGVLLMVATETHFILGGFVLVISASALGGLRWALTQLLFQNKKMGFSNPASTIFLLSPIMAVTLIILSFLIESWSSLLRSEFFTSGITRTIKTILLLLAPGVLAFCMVLSEFYIIQRAGMVPMSIAGIAKEVATISVSAWFFGDELTPLNITGVAITICGICLFTYHKYLKSIQSTIPLDGHGNPILPEEEIALHPRDDTTELDETSRLTSNSAENLEIHQVVSNVILRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVK3</accession>
    <name>A0ABQ8VVK3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_875164</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="11"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="113"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="218"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="34271" checksum="3659CD61D63A1BB2" modified="2025-10-08" version="1">MSRNNGSKKPVGFATHVTAGGIAGACEALTCQPLDTIKVRMQLSRSGRLPGTKPRGFFATGTYIVRRETPLALYKGLGAVLSGIVPKMSIRFASFEAYKTALADPETGNTSMGNIFIAGLGAGTTEAVAVVTPMEVVKIRLQAQQHSLADPLETPRYRNAGHAVYTIVREEGFSTLYRGVSLTALRQATNQGANFTVYQEAKKFAQRLQPGVEELPSYQTMMIGLLSGAAGPLSNAPIDTIKTRLQKSTAAPGSSALSRIMTIAREMWIQEGVKSFYKGLTPRILRVAPGQSVVFAVYERVSGMIERMRPSTGGDAYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVP0</accession>
    <name>A0ABQ8VVP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">KRI1-like family C-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_811267</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05178">
        <property type="entry name" value="Kri1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kri1-like C-terminal" evidence="3">
        <location>
            <begin position="512"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="592"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="639"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="611"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="669"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="685" mass="79160" checksum="075D7EF98C97D0BF" modified="2025-10-08" version="1">MSLLSDAESDSDFQLTINEHYAQAFQYKKEREELEQLKLKYGSDEEEDNSETDSEEDESEDEDGEELTPAVDAAILRTLARIKRKDPEIYNNKTGIFKEEQKKLGSTKPVSKRPKDKARPITMRQVAMEAQLQGDSRSPSPEPLTHSEEQRRLRDETIAVFHQLGGDNSEGDDLFVPREKTKDEQEQEEEEYRSFLEREVGGDLKTLVSVEENTWKEGTPPSTESKQKKKQKKKGKDVKKADDDDQEFLINYILNRGWIDRSINRVPTYKEVVAPKKGKGKATDEEGSLEGSLEDANPSLFKEDIHPTADSDIDEEEFEEIVDRFESSYNFRFEEPDAAVIQTHPRQIPSLIRREDTTRKEARQRRKKRQEEEMEKKREEVKRMKALKMKELRMRLDRIGQQGGKNAEDDPALQELDLEGEWDPEAHDQQMAALYGDDADYDEDGKPTWDDDINIGDIAMANDSESTRQKKKKKKKGEKAVEEDGVSVDAMDADIDKVDDNEWDGTEEMRKRKIEEYMDEVYGLDFNDMVGGIPTRFQYTHVEPENFHLSPTEILMATDAELNEYMGIKKFAPYRKAGKWDSNRGDRLKELRQKIGERGYGGDTTQEDKPVKKRKGKKERMRMKTVLDLDVGEDVEKEVEAAGKSAMPENLKRKQPSGDVLDESEEAQKKKRRRHKKKNHSEDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW17</accession>
    <name>A0ABQ8VW17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_751458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="2">
        <location>
            <begin position="42"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="234" mass="27173" checksum="6AF718881F7FD128" modified="2025-10-08" version="1" fragment="single">FFLHADEVVREAQFIVGSLPNAEQFSVERSLRLLYSIYHVLSTHNVRIERAWRDVRKDSLEVFRKIFQYLVDIGLLDPENSIQSLCLYVVYRNRIQASLDRTLSAWNNHQLRTEHHKTPIAIYELSREKAINQGYWTGDPGDDVRTASHPFYGQEDGDLPPLDELANDPTQPNYTPYNSKDEEKADGIFVNDDDEIQDVKDFLVAEGFDYDREDGNWGIDVYCEAVMKIQQLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWE7</accession>
    <name>A0ABQ8VWE7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TBP-associated factor 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_348326</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08045">
        <property type="entry name" value="HFD_TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045144">
        <property type="entry name" value="TAF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138:SF14">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="10">
        <location>
            <begin position="94"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="378"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="447" mass="46367" checksum="4A4B3A2A6485357F" modified="2025-10-08" version="1">MDIPIDPALQAQPAPGATPITPTATQAGQTTPAPVYQYTPYGYYQSYQNQFSSVPGVGTSATSATTPTPVVAHNNSTYTPAPANGIDTSDINTLRDALGSTGVDLRAEEESLQRTSDSHLTYRSYEDRTRKQPSKPNFNTIYLSSTIHQITSAHKLSNPNPSADTVNYLALALRARLQDLISAMITAARHRTDTQFDNAPSLYEDGSPMWSILVRSDVAKQIAALEKVEREEEIKIRRERKERADMAAAQAAALAAQSASAMNGGAGGSGGGDDDLDGFGGGGGGKKKRKKDGPGVTAKNMSVDVQKKMSNAAASHAAGLAGRYSWMTAGASSTGSSTPKKTAVAAAPAAAPATTTATTPGALSSSLTGAGASAASTTATLSTPSAGGSSSGWARPYVSAKKTTETNTTQEIVEEDTRTAITMRDAMFVIEKERGHGGGRGAAKGWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWH6</accession>
    <name>A0ABQ8VWH6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-ubiquinone oxidoreductase 9.5 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22903">
        <property type="entry name" value="NI9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039961">
        <property type="entry name" value="Nuo9.5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8746" checksum="D3F05312BAF59E6B" modified="2025-10-08" version="1">MASLFRPFQRSYNYLYRTAHEKPVMFYSVVLGVIGPVMTIAIPPLRESFGYVPPPAVPSSYPLPNRPRQPISGYDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWJ0</accession>
    <name>A0ABQ8VWJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_808784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="15425" checksum="85009D24D797D212" modified="2025-10-08" version="1">MEAKFDNKANILNARLLATHDNSPIYATKTNFTFRGRDITLLQDTNPALSTGSVTVGAIHWNDKIMEVNGQRKKVADLKEKRKDGFLNKVFRRARYWRWSAERREYEIKYTNDEWAATTLKSDGTSKINSIGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWP6</accession>
    <name>A0ABQ8VWP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="7">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_751007</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="10">
        <location>
            <begin position="46"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="25314" checksum="AE373E5578273E25" modified="2025-10-08" version="1">MDPQSDESKSYSSTGDVSIDRLAFFHILERLKTQKRTGWVDNNIQNPESISDHMYRMAVLSMCTSDKNLDVAKCVMLSVVHDLAEAQVGDIAPSHGISREEKSRLEAEAMHIFIHEMLHDSPAAQRIGALWKEYEDRETPEARFVKDLDRFEMATQALEYERDLNVSRLQSFYDSSIPYIEHPEVQQWGEDLLEERGRLLGAIHSAKLEMSEGDRLGEEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX78</accession>
    <name>A0ABQ8VX78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_892616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="14"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="375" mass="39613" checksum="8F3A48F4001122F1" modified="2025-10-08" version="1">MSQQKALLLEKAKGAFVVSTVPISKPGPGQISIKVIAAALNPVDWKIQAWDFFMKKYPAILGTDIAGDVEEIGEGVEGFSKGDKVFCQGFFVNEMAGFQQYTSIPADIVGKIPSNIDYAQAATIPLGFSTAAIGLLRAQPEGGGLNPTFDPKVNFSGEPAIVVGGSTSVGQYAIQLLHLLGYSTIIAYASARHTDYLKSIGATHVIDRGEIPIGRLAEAAKKVANAPIKIAYNAVGDNDSLAACIAAIVEGGQVADVNPQAKNEDSGNGKRVFAIFGSSHHPPHRDFAGIQWKTLPNLVAEGKIVPNRVEKVPNGLAGIDEGLQKLKANKVSGVKLVAFPQETALSLVHWVPTPGLHRPVSFVSLGHQRTAIPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXB6</accession>
    <name>A0ABQ8VXB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="237" mass="24557" checksum="58A76D9391416D12" modified="2025-10-08" version="1">MVAFHSIYAIEIVGILLAAVSVIPADAMPATRTVTGFEAQTPPNTLTEDLPTPLSTPTLVYSISVVGTTTTNGNTMTVYGEDIINSEYIQVDGYPVTNGDGSTSYTWSTEALSTTFTEHEIFEVGTTAIDFILNNGSAAALEPAINIECNFDSGASSETGVCTEVVQFPGQSTAQTTAWTGSIVPIFTFEVSVSATTTGSATNAAGSMKGGQWSGLLATTCIVTVFSSLAGLIYGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXT2</accession>
    <name>A0ABQ8VXT2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046418865" evidence="1">
        <location>
            <begin position="19"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="256" mass="28064" checksum="E307E6521284CB6E" modified="2025-10-08" version="1">MRVVPAYFFLALVSATYAAPAPVAPARSFHNTEAEAYASNLPSESRTPPELRAFSADVHDTMNTNLADGSNISSGTSPQARGTPIALELEGRQPGSDKPTAPMGAHSPSQTAQIQFVEQYDHTESGAPQGFKAGAPDCVDELLKWMIEIWQPNIQYALTYVNSFYEVLSDGFAQPPARFEFYVSGFAECFAKTAFVHDPKNSRKSTPPPPSCRVVVNSSKLKGKITVYQEDMKKGTSMLFSKELPENLWRPGMTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY12</accession>
    <name>A0ABQ8VY12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.157</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TSR3</name>
        <name evidence="10" type="ORF">C8R41DRAFT_893656</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1191) in yeast 18S rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63300"/>
            <dbReference type="Rhea" id="RHEA-COMP:13852"/>
            <dbReference type="Rhea" id="RHEA-COMP:16309"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
            <dbReference type="EC" id="2.5.1.157"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.157" evidence="6"/>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002621">
        <property type="entry name" value="PRK02287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426:SF0">
        <property type="entry name" value="18S RRNA AMINOCARBOXYPROPYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase L inhibitor RLI-like possible metal-binding" evidence="9">
        <location>
            <begin position="67"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal" evidence="8">
        <location>
            <begin position="106"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="238"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4499405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="308" mass="34912" checksum="5BADF00E7158BD17" modified="2025-10-08" version="1">MGRKNSETITSTSRGKRGRGAGYKGGSRGTFRGKLNRERDLDDWKPDSIIDSAEDEQEQENEPRIDVPVAMWDFNHCDPRRCSGKKLARLGLIKELKVGQGRYRGIVVSPKGSQVISPSDREIILKNGLAVVECSWARLDDVPFGKIASPHERLLPYLLATNPTNYGKPWRLNCVEALAAAFYITGFDTYAEILLAGFGWGASFWKVNRHFLERYRKCSTPAEVNAAQDQLMEELENNWEESRREKNAHPNDSEDLLFENPNHRREYESDDDGSAGEDWERNPREKSNEKRVNVPVGPPPSDSESDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYD0</accession>
    <name>A0ABQ8VYD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="476" mass="52835" checksum="B6BA56443AA0ED50" modified="2025-10-08" version="1">MSPACVSSPPSQPSSAKSQTKTTLLANTRTMNTTEPSSLLITGEFLGSKRARTISTSSVDTIRINSGKKKSTSSKKRARASEPSSGSECDQNILEDIRRIRQRKSSTYSADTIRALESPVVTFPIFCDPPERTSPQSETPSTAALKKKDPRKVTPPQLNPGKTAPSVAVTSVRHAPPPPIITNLVRSRVSSIKRPSSRPTSPAAILSNYHPTGFEPLPSHLQEWQPSSTHFMLSDDEGSACDDKASSQVTAWKDQWDHVHPGMSDLAISICFHKKQPFFDVWDLPDDIYIAVPARLHLTLKNPQQWKELPSEPDIRYIDIKCNTFEYRPLSEYYPPEYSVSYTGASSAEYADPAIIPADLTRGIIVNKRWNKTFPGNKFHFKETLITNFGRLPDDSLNTHSKDDGDSISKRGWFFKFMIPIPSWVLRQGNTRAFVVETSVWIGGLDNGGLLHGDTELVISHLRSEREMVKGVGQCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZK6</accession>
    <name>A0ABQ8VZK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_805916</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="39"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4501812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="519" mass="56276" checksum="3F9B92CE657DAB3D" modified="2025-10-08" version="1">MANTELKRDSSSVTMEHELKPQQPENSLASIAGWRKSILLFIFCFAQFLDAFNNSALFAAIPPISAAIGISDSNSVWLISAYQLTFAALLLTTGRLSDLYNPKWAFILGLLLMSFSSLGCGFVRSQVPLIILRAIMGIGAALNIPSALAMIIGMYPDPTAQGKALGGFAASATIGNVTGLFIGAALAAFVSWTWIFYLITILSFVMAAAVLVIMPLHISFMDGLGLSQGERFKRLDLVGVSTLTVSLVLLVYSVTTGSIDGWGEAKVLVPLILFFVLVVAFFQWEGRIPEHIAAVPPKMWRYQNFTILIILSLQPFMFWVATQLLLSWYWQFIFDWSTINVAIHFLPLGVISFPMIAVAIVLQKNFSLKWVILMGEILVIAGTLLLPFADSKPHYWRYAFPGFVLGSAGTTVVYATTNIALFAVTPPEVAGIVGAIFNCALQLGAAAGSAIITSIQTSTEKNHGGTSSFEGRAAGFWFMFTFTALEAIGVAIFMKNTVPALKAQNQGEGDQKEQQTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1U5</accession>
    <name>A0ABQ8W1U5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_805988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="60156" checksum="E5A550BD7F4F3DFA" modified="2025-10-08" version="1">MEDVPLEMPPLHEDGEQERYSPVPDSPQHMPLLDGDDGAVADDSAAALLPEAHEEPRSRSNDAGRRHSGGSAHTGESSSLVRVETNAETENPDPRGDVPAYFEVVDLNDEAQQRPPIPPIPSSEPTPTNSSMTAASSTASRGTSSRRSLRNLFGWSGRSPMTPPGLPSTSAQSHARADSGGALSLVSTMSRPSTSNRHSHRPSQSSSSVFSVVNPLNRKKSSATLSSNHLTSPSSISLASISAPLTHTVVRTEFTYPKAGPTPEQLKLISSREAFARFGVPYGKDAIAFAASTQDLNPPPEFESEAGPSSSSPPRSQSQTRVLARESIGRSSESSGESNGTNGLSSLETPEIRVHESSRPVSLSVEPDTPATSVEPSSPSQREPKVADLTHTSPLVDPTASSKDIVAHTEIPGTPSNARISPLINSPKDDIVPPHSTVSSVSPVQHAPLASPSTPTISSKPPPTSFRNPPASEAPAPSLRSESRTSSFRSFETARESVNEHGVLRAGSGSGTPTMSDSEYFSEQETEMGDSRPATPITQTSMTLPVRLLDGRDSSHHVLEGTDTTIRATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZUR6</accession>
    <name>A0A9W8ZUR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquinol-cytochrome-c reductase complex subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8J55DRAFT_526061</name>
        <name evidence="3" type="ORF">C8R41DRAFT_922717</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000041">
        <property type="protein sequence ID" value="KAJ4467463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZUR6"/>
    <dbReference type="OrthoDB" id="2391627at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4479502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="73" mass="8189" checksum="8375FF28664D18FA" modified="2023-11-08" version="1">MSRVFYKSRNPLQYYSFVFRNWTPSLATWGVGAGAGALLFLSVTPLVRRELLSKVPGIKGYFTDNTPASDKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A5Y3</accession>
    <name>A0A9W9A5Y3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8J55DRAFT_432617</name>
        <name evidence="13" type="ORF">C8R41DRAFT_820330</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000022">
        <property type="protein sequence ID" value="KAJ4475273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A5Y3"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000017">
        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="10">
        <location>
            <begin position="54"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="11">
        <location>
            <begin position="205"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4475273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4497953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="287" mass="32252" checksum="004A760B9071C9F5" modified="2023-11-08" version="1">MSRPELQAPPEIYYGDTEAKKYTKNTRNQQIQADMTYRALELLNLPPDEPAFLLDIGCGSGLSGEILDEEGYLWAGVDIAPSMLEVALEREVEGDLFLQDIGQGFGFRPGSFDGAISISVLQWLLNAETSHPTSSPPHRLNRFFTTLHSALRNPSRAVFQFYPSSDDQIQLITSIAQKAGFGGGVVVDYPNSNKARKVFLCLYVGGGGGQQQQIPQGLDGDVVEDGKVRFEKRRARDLRKDKNGKRKSQKVIDRDWILRKKELYRKRGKESVPRDSKFTGRKRKPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DIQ0</accession>
    <name>A0A9W9DIQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Guanine nucleotide binding protein beta subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_543508</name>
        <name evidence="7" type="ORF">C8R41DRAFT_802575</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000100">
        <property type="protein sequence ID" value="KAJ4468557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000027">
        <property type="protein sequence ID" value="KAJ4472479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DIQ0"/>
    <dbReference type="OrthoDB" id="10255630at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000020">
        <property type="entry name" value="Guanine nucleotide-binding protein beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="59"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="148"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="189"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="317"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4468557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4472479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="349" mass="38239" checksum="D5F1C50FB86DCB4E" modified="2023-11-08" version="1">MSQSQGDIQERIAAARREAESLKEKIRAKKESSADTSLRAMAAEVDALPRIVMRPRRALRGHLAKIYAMHWAADRRHLVSASQDGKLIVWDAYTTNKVHAIPLRSSWVMTCAYSASGNFVACGGLDNICSIYNLNSKEGTNLRGARELSAHSGYLSCCRFLNDRQIVTSSGDMTCMLWDIEAGVRVVEFSDHTGDVMSLSLGPNQNVFVSGACDATAKLWDIRSGRATQTFTGHESDINAVQFFPNGDAFATGSDDASCRLFDIRADRELNTFIHDNILCGITSVAFSISGRILFGGYDDWTCNVWDTLKGERVGVLTGHENRVSCLGVSTDGMALCTGSWDSTLRVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UVS5</accession>
    <name>A0ABQ8UVS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_872489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000202">
        <property type="protein sequence ID" value="KAJ4463201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="15619" checksum="2D8D0D239BB4F324" modified="2025-10-08" version="1">MAVRALQDLVEESPSTESEIYNFFEEAAPFLIYIHDFWMGRANCPLFAEQVLSSAESLTFGLPAFLRDNLTQQWGISPEHRSSAKDVFASLRGKGSTAVASPIITASTPLEIKSSASVSKTPVAPPRLLLLPGPPIQKTPIMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWS9</accession>
    <name>A0ABQ8UWS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="169" mass="19379" checksum="41F92BBFD3CAC59C" modified="2025-10-08" version="1">MNTNIRNSPTRGSRRNAAVSYDISRHLPINQLPPMQSHQHVNPRDVVLSSMPQFMRTMFANDARRLRNPRSRNDNIPLTPPGLQHPYRTLQRVTALPPGVPPPGLSTPSQFKVPLNILYLRILETMFRPITNTRPIPVYLRVKGMVSSDELGKRRVHPPFPRPLHKPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXY8</accession>
    <name>A0ABQ8UXY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_891298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF34">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="2">
        <location>
            <begin position="27"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4465351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="34655" checksum="A1D8939E1B98E383" modified="2025-10-08" version="1">MVTFNKPSHFGVLTLASIIALNKANAHGQIKGVLANGIYNDGPNIYWDADPVNEQTATRKMYQAAGPSYVLPQDFSDNSKMACEGAAGAPKIINVSAGSDLRVDWVGATSELDGKPGTGNVPAGQNPWVHAMGTMASYIAKCTNDDCTTYDASQGSWVKLAMFGIDKSETISSDLRETMKNKPEEYYPTPGTSGLWGMARFIEASSSWTVTIPKGLANGQYIIRQEVGAIHNPWNAQDDTSGTQLYIGCIQINVINGGNTKLPGGTRAGSLYATSGAFARYNVYEDNGMTFVDPGPVLWPSSYAKREEWRMKKVKRCMKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UY23</accession>
    <name>A0ABQ8UY23_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_861080</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000155">
        <property type="protein sequence ID" value="KAJ4463697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="14">
        <location>
            <begin position="133"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="56"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="390"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4463697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="539" mass="61161" checksum="51687B72E74585BD" modified="2025-10-08" version="1">MPVTHSVPVSHQAPLHTVRKHEHDEPVVILQESASEDEPRVYVHYVNLEKRNDEWVPKSLLQPMPSTSTSNGAVPSKKRKRSSSKRPSASASRSYSALSDEDSSEGRDSNGQPAGEVVMTEEEYDLQHHKKINTRRNFAQVCVGEWLIKTWYFSPYPLTENEDAESSIASQEKAISAVNRIPGVYRITNRSHGRTSDMLAGGMGRLVEKEILYVCEMCFKYMTDAPTWELHKKHCTVSHPPGRKVYQRGAHTIWEVDGAREKLYCQNLSLFGKLFIDIKTLFFDCDNFLFYILTDATRNNDHLLGFFSKEKVSYDDYNLACIITLPPFQRKGFGRLMIEFSYELSRRVGKAGTPERPLSDLGLRSYLAYWVSTLIRFFRKLLEVMPVSTGPNPVISRGTPPDFRSPSRELSSDEGSAYRRRKRNKGWQGEASEDEVVEDIDEKLASFRTFITTRNPDGSASVHLEIQCSLADIADATNLRVDDTAFALNEMGMLKRWGKLSGSDEEQPMVVLTREIVEKVAQERGVKDGSVLHLSHVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ91</accession>
    <name>A0ABQ8UZ91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="148" mass="16423" checksum="7F68990F881A001B" modified="2025-10-08" version="1">MATSESDVSSKSSSSDGDSASDVDANGTPVESGVSRVAKAYAQKGIRSSWSRSAQRNQLNKLARRIIRETLGGRKNYQLFVCPSVSDGRLKEFEQNPQAYGPKIRNTFIDKRGLTTQHLLEQPWNQQVTTIMAKNAEQIAKNCKDERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0Q3</accession>
    <name>A0ABQ8V0Q3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GPR1/FUN34/yaaH family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_872135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000141">
        <property type="protein sequence ID" value="KAJ4464388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4464388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="270" mass="28822" checksum="1F74EB19632939DE" modified="2025-10-08" version="1">MDFMHDIEKGSIEQQGVTGRPLIQLTPEQFERLFLAPHPDTGNSPAYRLGVQRFGNPTPLAMIAFLLVQAPTACIQMGWGGSTTAANAVLTGPYYLLGGLGLVISGLMEWIIGNTFSSVVAITFGGNWLALATITDPAHGIASTFPSGINSPEYNKALMFYLAFWTFLTSVYFVASLRSNIASASVFVGQGVFFNISFANGLNAAGYGELGNGNQVLADALFKAGGAFEFVVVCASGYLFVALMLESVEMPFRLPLGDLSNVFTKKTKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1T3</accession>
    <name>A0ABQ8V1T3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_777721</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="244"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="348"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="694"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4469811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="757" mass="83621" checksum="8539BA2B96FFDAF3" modified="2025-10-08" version="1">MSVDARKAGESLILIGSLVYASSKIWEGTNFHSPNFDSQQYNLWVLTELHCLVGATVLYVLWLSNSLISSKANPFTSLNADAAAPSMTSKRPSSPRIPETRDSNFKRNVPLLLRKRADFGFVWMSVPRNYRESSDDGILTGLLFGPLVSSALLYSSLTLPSSATPLSSWRIEAPRLLSNAKDSYSALEALVLSRYNLVDLSNLCSTILLLHVCASWWFESRYRVAAATLDSERKSVPRSAGKRLSYFVVFTLGITICMLGIKFALVYFSLGIWQHLNWFEITVASLFYQCTLYGVVRLAHRGFTLGELGIVSFGGTALFMEFLNVTAARIWPLTTPYIKTYRLPTPLLIFQTALIAGSFLTGFVLSPFLILSRHIGQRPVRRMRYPELKLRQRRLLALGFYVGSFVMTMGLIGMWTYWCLGKRNPWLWVIFYILEGRKGWSRPALLIYWIALGSLSVAGWNRQLARSRKFRAWNTAGENLIVPGSGGAFMGPPFVDGLVPQSSGNSSDTQNGSSVSGGSGSTMGLTFPNLSNLPNLPHLPNGVATDLLDAADKHVPTLRLNARRKFFHALTVIMFVPGVAFDPAFTHLSFSVAFALFTFAEYVRYFAIYPFGASIHLFMNEFLDQKDGGTAILSHFYLLTGCAGSLWLEGSSPLLLFTGILVLGVGDALASIIGKRVGVHRWSPTTTKTLEGSFAFTLSVVISAWILRLFGVTESFSTLRYTTVIGTSSILEALSDQNDNVTLPLFSFSLLALVGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V271</accession>
    <name>A0ABQ8V271_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Acetyl CoA carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C8R41DRAFT_924813</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0092">Biotin</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="18">
        <location>
            <begin position="38"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="190"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="16">
        <location>
            <begin position="673"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="19">
        <location>
            <begin position="1471"/>
            <end position="1809"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="20">
        <location>
            <begin position="1813"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="2024"/>
            <end position="2051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ4470478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2231" mass="247430" checksum="EC2807EBEADD6F70" modified="2025-10-08" version="1">MSAYDHSRVQYFIGGNSLDKASPSSVYDFVKANGGHTIITKVLIANNGIAAVKEIRSIRQWSYETFGSERQVEFTVMATPEDLKVNAEYIRMADRYIEVPGGSNNNNYANVDLIVDVAERAGVHAVWAGWGHASENPRLPESLAASKNKIVFIGPPGSAMRSLGDKISSTIVAQSANVPTMPWSGTGITDTALSEAGYVIVPDQAYQDACVTSVEEGLVKAEEIGWPVMIKASEGGGGKGIRKVEQPEAFKNAYHAVAGEIPGSPIFIMKLAGAARHLEVQLLADQYGNAISLFGRDCSVQRRHQKIIEEAPVTIAKQDTFEKMERAAVRLAKLVGYVSAGTVEYLYSHADDSFHFLELNPRLQVEHPTTEMVSGVNLPAAQLQVAMGIPLHRIRHIRQLYGVAPNAASEIDFDMIKPDANQLQRKPRPKGHVVAVRITAENPDAGFKPSSGSLQELNFRSSTNVWGYFSVSSAGGLHEFADSQFGHIFAYGEDRGESRKNMIIALKELSIRGDFRTTVEYLIKLLELDDFKDNTITTGWLDSLISDKLTAERPDATLAVICGAVTKAYLASEACWTDYKRILDKGQVPARDVLKTVFVIDFIYENVRYSFTAARSSSTAWTLYLNGGSTMVGARPLADGGLLVLLDGRSHSIYWREEVGALRLMVDAKTCLIEQENDPTQLRSPSPGKLIRFFVDSGEHINAGEQYAEIEVMKMYMPLVASEDGIVQLIKQPGVSLEPGDILGILTLDDPGRVKHAKPFEGLLPTMGTPAVTGSKPHQRFIRCLGVLNDILDGFDNQAIMASTVKDLIDILHDPELPYSELTAILSSLSGRIPAKLDDSIHAALETAKAKGEFPAARIKKVLENFVESSVLPQDRPMFRTQLGAIYDVLDRFTGGLKGHEIKVWSNLLEKYEATERMFGGSIEARILTLREQNKDDLDKVISLVLSHIKVSSKAKLVLTILNHIKTKGISVSNAESPLYKVLQDLASLEAKSSTSVSLKAREVLIMGQMPSYEERLGQMETVLRSSVTSQYYGEQVNTVHTPSAEVLRELSDSRYTVFDVLSAFFEHEDHMVPLAAFEVYIRRAYKAYTLLSIDYEEGDELDDGDSPSIVTWRFNLGQSHSPPSTPRISLSGESKRSASVSDLTYLISRHQSQPIRVGAISSFPNFLALAKGFSKVASALPLFDAIEYNSRYGNPQSHPNVLNVALRLFREEDDMPEDAWFEKLTAFVNKQSSTLREHGVGRVSIMLCRPSQYPVYLTLREVDRVWTEEQSIRNIEPALAFQLELSRLSSYKLKPVFVESKQIHIYHAVARENQLDNRFFVRALVRPGRLRGSMSTAEYLISETDRLVTTVLDALELVTAEQRNTDCNHIFLNFIYNLAVTYEDVLAAISGFIERHGKRLWRLHVTGSEIRIALEDDEGNVTPIRCVIENVSGFIVNYHGYQEITTDKGTTILKSIGEKGPLHLQPVHQAYSTKESLQPKRYQAHLIGTTYVYDFPDLFSKALQNLWDNTRATNPTLVKPKVLLESKELVLDEHDQLAEVDRAPGNNTFGMISWVFTMRTPEFPQGRRVVVVANDITYKIGSFGPMEDQFFYLVTQYARELGLPRIYLSANSGARIGLAEELIPLFSAAWNEEGHPEKGVHYLYLTHENYLKLEEQGHDSIKTIDVEVAGELRHKITDIIGLQDGLGVESLKGSGLIAGETSRAYDDIFTITLVTARSVGIGAYLVRLGERAVQVEGQPIILTGAGALNKVLGREVYTSNLQLGGTQIMFKNGVSHLTAGSDLEGATHILKWLSYVPEVKDGALPVLESSDSWDRDIGYTPPKGAYDPRWFIEGKTDEATSEWMSGFFDKGSFQETLSGWAQTVVVGRARLGGIPMGVIAVETRTIERIVPADPANPASFEQRIMEAGQVWYPNSAYKTAQAIFDFNREGLPLIIFANWRGFSGGQQDMYDEVLKQGSKIVDGLSSYKQPIFVYIVPNGELRGGAWVVLDPSINSEQMEMYADVDARAGVLEPEGIVEIKFRQNKITALMERLDTEYASLKRESKDATKTAESRSAATAALERREAILQPTYKQIALLYADLHDRTGRMEAKGCAKPAIWKDARRKFYWAVRARVARSAALAELTEASPGSTTEYRSHLLDSLASIDAAMNDREVSETLEKLDLSQTVSQLKADYLMRRMVELTKEDRKAAMNGFARLADNLSDEERNSLISVLQSATRSPAPPSYATSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2P9</accession>
    <name>A0ABQ8V2P9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_71323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38669" checksum="E7A1A3DFA145CBBF" modified="2025-10-08" version="1">MNWVILTARAYSSFLLGFSCSTYPFLVMADTHSLVSVPQKRKMELEELSISDNNTGNDFMNIDDHLMTVKPPKLRRILAKYPEEDSSANFSSHNVESYFLESVAQSHSTIQSIETITEHYRKISFRILRINLLHRDATARMDKQPHIIDDIYDINGEENKLAWPLNMPPKEPVIIVPKPRAADIPIHSTRVLRSSQRQSTSSPSTSKSSTPVPPALESPIIIPLGTTSKDTLESSASPLPSPEALVVKTDPELCQIPPYKKLPSRGDSVQKRIAKLQADPWSDASKLTAKSVFCIGCQKSVCLDKRFDYYPGFWETHKRRCPFVQNGTPKQDETVTVIEQANST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2X4</accession>
    <name>A0ABQ8V2X4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_852660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000094">
        <property type="protein sequence ID" value="KAJ4469830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="24500" checksum="BB194861F5BBD60F" modified="2025-10-08" version="1">MTTDCMTNNSLSAAPESRISVTPFLPAHLSFVTSSPPINHIGSISSQKPAPDFTNPFSSVISNLPSVPVPNPSRDPSVHVRFNTRSAARRTSSPQSSFSSTDVATVRGRSNSMGSHGGYTRGSFARTRSLSRSFWASPTSPPTGPLPDPPPDVPSTSSSVKDLQPYRIDMTSPNHSNSASLVLPVVSIPGPSAVAVDFLARQGRTPSRRRHTQSRLVADILTFEGDSEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3S4</accession>
    <name>A0ABQ8V3S4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_924582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4471222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="375" mass="41122" checksum="05DFBC9AC114DD91" modified="2025-10-08" version="1">MDTQESSLSPIPSEQQLPNVAEVVGSPVLFSHQLASQFELGDMGRAELSEVAKCIGGQLPPAMVMAHLYSLAAQFKTHENQQALKREVANLTLKVDTISESIETMPTLTKPQKDDILATCKLVVYNPVHIDYDNDSIVQDGKLKEQGSTNSFKSFFVQESTSMKRVVKDHVRIQASYAKSALRNAIIKSMRVGVTQATSTIAGSMGSSTKILVQETSQVILLRYFVRQERPDLFDTSKTKTKAKTRKSSKRAHVNGDNFAINWQATNPSETTAAPILTTAAGTADTVHEGQSVNEIDEQESKATAWASGFTEWINSKINGTPGKDDALALILTLTVASIKNSSRKSSCFFHKTSFQTFLANELPPFPLSHIQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3Z6</accession>
    <name>A0ABQ8V3Z6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_850684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="29918" checksum="C05479695777B49D" modified="2025-10-08" version="1">MKLRAFKRIAKFIRPDRAKQSQYDSPTTYTTAPARGPKTQTNRPNDGPDESLFGTYALNGQDNTVSTIAPRPASPRVFDYGSPHLDSALQHDHPVPYPTEDLPALQQHSHVHIGGHVIFPVGPIDYLLRIEEATPGPGCNCLIPAGEMQIASPNMNIVLGPGRRVVLLIGSPTGEGKEYVAEVIKHYILTTQQLEAGMRVRRNIAEAINILNTQLSVGGDVGIHINIGEDQQVPQRPLGDSSRPATATPVQDNGKGKRREAAIIVSSSSIQNSFVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V455</accession>
    <name>A0ABQ8V455_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_925827</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60876"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="Rhea" id="RHEA-COMP:15719"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
            <dbReference type="ChEBI" id="CHEBI:144051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. NudC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF6">
        <property type="entry name" value="NAD-CAPPED RNA HYDROLASE NUDT12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="244"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4467277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="422" mass="46180" checksum="5B1CD6224D3F877A" modified="2025-10-08" version="1">MFAGSPLNRLSWLRTSHSFLNSIIASPKSRWLLFKSGNPLTSKSEGKSILAYLSTKDVGPFIGEAPHFGQGKESGLLTSEEQITATEGVRHRGSPIVFLGLHENTSSGSGALPSSDFIDADKAVSKLEGVPYFAMDVADLEMEDSAIETALKETDATKAGTTLTWLDARSVMTNANLFDGAIFAEARSMIDWNTRNKFCPGCGSRQHSLWGGWKFGCSTLMPWSDNTGRKPCPSGKGLHNFTHPRSDPVVIMLAVDETGEKILLGQNNRFKGQFYSALAGFIEPGETFEDAVKREMWEEAGVKAWDVQYHSGQPWPFPASLMCGFYARADSTQPVRVDLDNELSDARWFTREEVMSVLNHATGSYLDLAKLAEASSQLNKDVSDPPFRVPPTTAIAGVLIKDWAEGKVQFPPFALNSLKGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4H7</accession>
    <name>A0ABQ8V4H7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_888373</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="8">
        <location>
            <begin position="160"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4473535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="309" mass="34651" checksum="92D32D0CD3C6A3CC" modified="2025-10-08" version="1">MSFLSRVHQHSLRSSLLGTRLSIANPSISTVPHSCRWHFLFKSTSRALALPSTSNAAHHTRLNDLGIKSAWLKIRQQSGRVRTPLRSHGYGGGGGSKRSPFDFLDRIPEDVVFWGIIGLNGAVFIMWQLAQKRYEIERDPRSYIWMQENFTTSWANFSSGRIWTAATAMFSHQGFQHILFNMFTFYFLARPVLSILGPRRFLSLYIGGGLVSSFGSMYWHNKIKHRDTSSLGASGAVFAVNGFLACVAPKMIFQIYGIIPVPAWLFVSGVFVFDVMSAMSDKRRETDTAGHVAGILAGIAYYLLKRFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4J0</accession>
    <name>A0ABQ8V4J0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translation protein SH3-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_801016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_bL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="Ribosomal_bL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4473550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="19991" checksum="DF3BBBA83E627EE1" modified="2025-10-08" version="1">MFNIFRWTSRSLTRTMATAAQTVSKPYPFSKTAIILPEPYVAPPLPLVQGKGLMPYLQKNLTTPEKQTMLRELFSRHSAKRIYPGSIVGVTLEHAPFAFTGVVLAIRRRGIDTSMVLRNVIQRTGVEMQLFVNSPHVKTIKVVQKPPKGRMKRAKLFYLRHSPEKMSALAGSKKGTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4N7</accession>
    <name>A0ABQ8V4N7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_923926</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025795">
        <property type="entry name" value="tRNA_(uracil-5-)_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="RNA M5U METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061:SF30">
        <property type="entry name" value="TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51622">
        <property type="entry name" value="SAM_MT_RNA_M5U_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="7">
        <location>
            <begin position="92"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4474161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="548" mass="60945" checksum="C5C6B7A9D8337604" modified="2025-10-08" version="1">MSSSKATEAETKLSEKGPGKRPRAPSPLSQAEKQAKRAKSVARATAKRLKKQRGHVPEVCSPEDVRWTDIVSLLGQDVVDKAAEDGSEFNSPFLFKSEVELEVKAISSNGEGLAQSDEEDSKPWVVVVPFCLPGERVKCRVFKNDRMHSLADFMQIIRPNSVLRDNEKVNCKYFSKCGGCQYQMLSYETQLAFKRNVVVKAYKNYSGLPESTIPEIQPTIGSPLQYGYRTKITPHFQAPPPKVDRIALQAQVENDDKPDWLQIGFNIQSQNKVFDIEECPIATPVLNRALPEIFQNVVKTIHTYKKGATLLLRESLDTSVDPDPSDTSKDTKLCITNNHASIRERVGGFLFEYVASSFFQNNNAILPALTSYVREAVASLYPDPDDPSRPTHLIDTYCGSGLFAITLSPDFSTVAGIEISADSILYAKRNAKLNGIVAEKMTFRKGDAAEIFKTVSDFPPEKTVMVIDPPRKGCDDLFIEQLLEFRPKVVAYVSCNVHTQARDVGKILKATQDSVEGEGKKYVLESLRGFDLFPQTAHVESVAILRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Q5</accession>
    <name>A0ABQ8V4Q5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Laccase lcc6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_984742</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13856">
        <property type="entry name" value="CuRO_1_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13903">
        <property type="entry name" value="CuRO_3_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632051" evidence="7">
        <location>
            <begin position="20"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="34"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="162"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="363"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4467834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="524" mass="55516" checksum="175F97540FAFE8D1" modified="2025-10-08" version="1">MNFVTALPLIAQLIGTALAAIGPVTDLHVVNKFIQPDGFNRSYILAEGVFPGPLISGQKGDNFQINVINELTNDTMLLSTSIHWHGLFQEGTNWADGYAFINQCPIAAGNSFLYNFNVPDQAGVFWYHSHLATQYCDGLRGPLVVYDPQDPYLSLYDVDDDSTVITLADLYHVPAPLIVGAATSDATLINGLGRYTNGPATAPLAVISVTLGKRYRFRLVSISCEPNFVFSIDGHTFTVIEVDGVSHDPVVADSIQIFASQRYSFVLNANQIVGNYWIRANPSVGTTGFTGGINSAILRYVGAPVADPVTVSTSVNPLLETSLHPLVSPGAPGSPTLSGVDVDLRLVLGFNAGSFLVNGVKFVPPTVPVLLQILSGATTAASLLPAGSVYTLPLNSTIQLSFDASAVAAIGGPHPFHLHGHNFDVVRPAGSTTYNYVNPIRRDTVSTGAATDNVTIRFTTNNAGPWFLHCHIDWHLEAGFAIVLAEDAPGVAAANPTTDAWNDLCPIYDALTSAELGGGGGPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V503</accession>
    <name>A0ABQ8V503_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-mannosidase A</fullName>
            <ecNumber evidence="5">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Mannanase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_923903</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF5">
        <property type="entry name" value="BETA-MANNOSIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046615428" description="Beta-mannosidase A" evidence="12">
        <location>
            <begin position="20"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="14">
        <location>
            <begin position="29"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="13">
        <location>
            <begin position="880"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4474567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1020" mass="112003" checksum="BDF7CF155E565B44" modified="2025-10-08" version="1">MALLRALLLGLSLLHCAFAAIFDLSELSWSLKNENGSIVVPGTVPSQAHIDLLKAGVITEPLLEINDFTQRWVWMDNWTYTADLSGFFDTLQPASSDQTLLVFYGLDTIANITFAGIPIAWVNNQFRQYVYDLTPHIPAAAASGGNLTVEFESAFWYGLNVSSRPDAEFFPGGNGVFEVPAARHYIRKQQIDFGWDWSPAFVPTGIYKPAYLVTLANESDASSITLSSTPPLSPSGSTNTSDVIFIEEVAVDIYKLGSSFTVLPDQSADWVVNVSLAIRAGASVEAPTVQLALPELNVSSEAFTIPTLNGHANETVWAIVQWQIPDAVPQRWYPHNLGTPQLYNLTATLSLPTSSPTSEPHKVSFTTRTGFRTIRLVQLPVPQSDVTERGLTPGDQYHFEVNGKEFWSKGSNLVPFDPFYSRITTDRVQWVLQSAVTSGQNMVRVWGGGILQPSNAGTAGGVYAFYDLCDELGILAWSEFLFSDALSPINPFFLESVEPEIRENVRRLNRHPSVAQWAGGNEIEGIVISTNQSLPNGTIYLDQFVTMFQDFLHDLETSESRSVPYTDCSTTKGFLSLDPYILRFDNGTSGDIYGNSERFDYTATDAFDYSTYPIARFVNEFGFHSMPSIYAWEQALLSPEDFAFNSTVVVSREHHNPAGSLAFPNPNAPEGQAEMTLAAEQWLPVPPFLGSNSSITSGSAQDNATFAAWCYTTQVFQALTIASEINFYRRGAGLPENNLGGIVWQLNDIWQAPSWSSIEFDGRWKVLAYAEERAYRPITIHPFWIPEAENLEVSVMSDILGSDVQGTAQMTWYDWSGKVVLALPAVKFTVPSLNFTAVLNQTGLDTILPPGKGVQDVWMLVNVTADVPGFTPTSLGNVTLVDPEITVNTGYSYEFVLEAKGGVAPWTWIEHPAGTVGMFIDAYTGSPSNAFYLIPGVQKIVRFIPNTALSTVQDPRPIDFVVRSLFNNTILDTGSKVETEVAVDAVQVISTSTVDTIDHAPAKPHFPGHGHDGQIPVVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V540</accession>
    <name>A0ABQ8V540_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Clasp N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_775652</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567">
        <property type="entry name" value="CLASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567:SF9">
        <property type="entry name" value="CLIP-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="7">
        <location>
            <begin position="367"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="639"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="652"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="699"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="712"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="737"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4473534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1318" mass="142494" checksum="A04CE96E31B990FB" modified="2025-10-08" version="1">MESDDSRLDALLSQCKSNDVDVKIDALTKIQAEAEQGLEINDPDALINVLKSCLRISNQHLTTATLSALPTLLPLLISRPLNAPPPRLPANGQSSAHSSTSSSSPSSIVDAYALRQLLNAFLPTGGLFERLGDKEKAQTKAREALVILGGFAFRAPGSTLATMSTGSRSGKGPETSLVVFERFLRENGLSSKVWKVREQSILTLVQIRRQHHMFPLRPYLPLLVDCLEDTDAHVRDCARQSVVELFSGPSVTDAARTDLKKEMAKKGVRKTIVDGVLSKILNGNGPDSNPQSPAGSESGDGKPVSYVPPSLVLQGRKASGAPTPLAPSLSQSGIIRPPSRAAALDSSMPPTPTTEVPSEVKPVYIASVRDLENEFQGMEKAFEGKETEHNWSTREQYILRVRGMLKGDVHQKYFDSFLACLKQSFVQWSLKTLASLRTTVCTNTCALYQELAAALGTSIDPLCDLLLTHLLRMAGFTKKLTADRSQAAVNSLIMYSSGTPRIFISLISQISKEKNVQARNFAMGHFKAYIDIHGHRAKSAIESFGGVDILESAIKKSLGDPNAGVKAAARAAFWSFNEIWRERGVAILETLTPLARKEVEKVCPNPELALSLPPTTPKPAKKSSVAAAIAASRAKAKAIATAPPSLRHQATSASHIAPARRSASPSLSKSTSRSPPSRPSSPLRTSTGSSPPRSRIISNTMPRSISTTAITPSMSRPVPRSDSPPSPPSPVSDSFSRRLSSPLATGISPTRPTTIRRAMQTTLPASPHSTESPPHRSISRVQPAFAAAAVRMSSLMPTLNGSDEDSLLLATAIPLPDGDSDSDEHSINLMSFSAPYEMYHPPPASDSQAHSVSPNSADFNPIIGVSNALSTDSVTELAQGGGAPVVEDALRARAEQAESAAERLLELVEPEDDIPHPILPPSLLVGSPVSNGLSTPGKSKPPPVSVAQFPVTPKNRASIVMRQAALFQDSPAYNGRAPSLLDVLQDRSKETGWWLKRKTLLGQRIALGITESSNAQTDLENYISILEEGDPHLSTLQKLVFLCIENPAIDVLSPLSPDSLYLMSPSPFTSSGPVPTLHRDMWEKNRNFDKLFNALGSYMVSTKDEIQIEHGLMVLWQMLESQSIHLEGREGDVFTLLLRVRYCNKFNVLEATNTIRDVLTARIEPVYGLTTLHASLRTFQSEAPPLEDDAEVKAASYAFGLIALGKFILRLPAEIAEEELPRLRDTLISGLNDAKSLVIREAAAAAIISAQLVLRDETHLFALLDGLADEKKNLLTYLFDKHGARGLSHSLGRTGVDKLEKEMRRLDSRTSTPPRQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V598</accession>
    <name>A0ABQ8V598_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_847777</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048899">
        <property type="entry name" value="NMD_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21193">
        <property type="entry name" value="NMD_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="14"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 SH3" evidence="11">
        <location>
            <begin position="245"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="309"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="490"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4474796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="550" mass="61613" checksum="F1D078841266C328" modified="2025-10-08" version="1">MEFVPAPAVHRVLCADCGTPIVPNSANLCVACLRNTVDITEGIPKQASVSFCRNCERFLAPPQAWVLAKPESSELLALCLKKLKGLPKVRLTEAHFIWTEPHSKRLRVSLTIQKEVLTSTILEQTFEIEYLVQHGQCPDCAKLAAKNTWKALVQVRQKVPHKRTFLFLEQLILKHGAQKDTISVKEVKDGLDFFYSQRSHAIKMVEFLTGVVPVRSKASEQLLSSDTHSNTANFKYTYSVEIMPICKDDLVCIPPKQARQLGNISPLTVCTRVGSSIQLLDPATLQTCEITSAIYWRNEFNSLATVTDLVEFTVLDVEVDGRSRGKFVLADAQVALAGAFRSGAGQDEDSMDYESAGYTNQIYHTRTHLGGILQPGDTALGYFLTNSNYNSDDFASLPAERIPDIMLVKKTYPNRRKKNKSRGWKLRSIGKEAGEEGETGSGRGVVGRLGGRDQKKVEEDYEHFLRDLEEDPEMRSAVNLYKSTDVNMKTETKRGPKKPQFAMDVDETPRQIEEEEEEEADFPEIQLDELLEGFDEMTLGEGREEVVEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5C7</accession>
    <name>A0ABQ8V5C7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_743775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="171" mass="18612" checksum="92AB5A3D06B302E9" modified="2025-10-08" version="1" fragment="single">PLSTSACEGDCITNTTNEFIRLYATPLKTLLDHTNTDLASRFNLPSSSQCVSHLQDAYATIAYAYLENAIFPSYFHGKCQQRTANGTLVNPPGCPNPDCPVVCGTPGSMVHHYDALRNITVNSHEGMFALLTKQDSGSFQDVKTCVLGATTLKKCPKEPARTTRSFSRSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7U0</accession>
    <name>A0ABQ8V7U0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_772348</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000064">
        <property type="protein sequence ID" value="KAJ4478930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="710"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="35"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="232"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="429"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="837"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="872"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="957"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="876"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4478930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1006" mass="114330" checksum="080FD71EDFA977FA" modified="2025-10-08" version="1">MLPSYFTLLFDDGNGTQPDLPPGSPPTLKFEGPWLTTQLILSGSIGIISFLIFSYSRTRWPLLFAPRTKLKGFSPHEAHAHQAFFGWILPTIRTSEFTVLQIVGLDAAVLLNFFKMAFYLFSVCSFFAVTALMPLNWKHNKRLGDDNDGNEPDDDWSALFVSYSFEPSQNSTLPTDDSWLGLISDANTYLSVHLVFTYLFTGLSLYFTYKNYRRFIRSRQLFSLELVHSIPARTVMVTNLPQHLRGERSLAEYFESMNMSVESVSVVREVGSLERLLNKRTRALLALEKAWAAYVGNPSTVEEYDPENTAVVNLIEPDTESGPTTRLVVPHRQRPTIRPGWFKPKVDALEYLENRFGEIDEIVKRRRRTGKFKATKTAFVTFEKMSSAQIALQTAHAPNPFQCVTYASPEPRDIVWANMTSSDHTLRARDILILAAIGLLFFFWVIPIAALASLLSYEEIKKTLPWLAGLIDKNDKIQALVQNSLPSVAMITLNALLPFALEGLTYFQGYRARSWIEYSLMKKYHLFLLVNVVFIFLVASTYWQLVRDLANFPAKIPEKLAKSLQSGRARNFFLSYAILQGLGIMPLQLLNLGVIVPRIIMRLFFTRTPRDYAELNAPPMINYGVVYPQAILMFTITMLYSVVQPLIVVFGAIYFGVAYVVYKYKLLFVFYKPYESQGQAWPLTYVRLVWGVLIFLVFMTGFFLLSKSFVLSSLLVPLLAGTVIWSWWLHKSLTPLSDYVNLSSVFEVERGEESADVARLKLGHPVTWSQSNLNRRRYAQNDDTLYVAPEDERTDYSQPPMANWYRGVLNTGKRRFGHPALNGVLPEPWLPLKKGQTLTNHENRNNGSPRQGNDSNQAVVLTLRKRASVVRRSRLISRQTPTSESAANNSNPWQDAQSSTRRTQTAPDVIHHRLSFDHATGVIMIPDDENWLAEDVDSDEEDYGAAGIDRIQRTQTEPTISGSEVVSEDEDLPIAASPSRTSRYGTYFHHPERRRQTIPGAFPRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V867</accession>
    <name>A0ABQ8V867_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_851873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000091">
        <property type="protein sequence ID" value="KAJ4470494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="16245" checksum="2151E5F6A5B9BB2E" modified="2025-10-08" version="1">MPQSKLILYVALTTFALFGLLFLVCQFAPVVSQWKNKKQVKQDLDIEKLNFEYSRKLCQEGNLNSEESLPSGSLAKMISGLSFECGAPFVPLINAVTSSSMPLPPSLLYPLHQNVFPHIFIEARSAILQRLTWLPYVYQPLQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8S4</accession>
    <name>A0ABQ8V8S4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_896824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="95"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4480744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="367" mass="41405" checksum="B8FDB9E0C25393E1" modified="2025-10-08" version="1">MHVKRVTLTSKKNWWMVEMDEENESKQPTSSADTVVDPFHYNDYIKHEIQGEHTRTPSTPTPTMPPMNYKIPRHPTAIFSFPTPTPYSAPSGNPTLTLAPCANGSASELFKCIVKKPDVVQMEINDEMQSNASDVTVQFLAELRVYTTVQTHRNICAFLGSLENVGMVLEYIDGRTLFDVISVRPELTISKKIDYHNQLLDGLTHLHSYGLSHGDLSLLNIQVTNSSDTIKLLDFGRSVSADSVYANPEAEPIDPFTALAKRTSIFSPLPPSKTEQIHPGTRPFCAPEILRGECQDARLADAYSFGLIIVCLDRCETVDIKPWDQRKDLLPKDLFEGCSVFEDRARAYLQKWMARRRLMKEDKMALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8T1</accession>
    <name>A0ABQ8V8T1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_869101</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="6">
        <location>
            <begin position="120"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4480299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="235" mass="25885" checksum="42311BB1CD136EB4" modified="2025-10-08" version="1">MTTHALVTLDEPMTRTRRRSMRNLAESESELEETRPLKRVKRVNEPSKSSTSPSRLKTKVRAPKHPTSHAAPAHWRQAYDLIHGMRCARDAPVDTMGCDVAGEAESLQNKRFLILISLMLSSQTKDLVTHTAVSNLRSALRGLNASALACAPPSLVQESINKVGFWRCKAGYIQATAVICRDKYGGDVPRMLGELLELPGVGKKMGYLMLGSGWGLNVGIGVDVHIDMTQFYLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8U8</accession>
    <name>A0ABQ8V8U8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_922355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF38">
        <property type="entry name" value="LD27581P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="181"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4480761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="274" mass="30113" checksum="FE028FE97AEB5838" modified="2025-10-08" version="1">MSFQDIEAGFGPGASNNNISLATPESPEDAAFRSLQSSLSLQMLKMNANVQGILKLVDQLGTGRDSAALRKSLHDLTDTTRAMAKRGSEDLKKLTTQQTKLPHQKASLQKTSHDFQLSLVGFQRAQQLSADRQRTVVQGVKMAVEDNGEGPEANEPPSSPSQRQAQLLQAQLSPHELAYQESLIHEREEDIREIEAGVHELAEIFRDLGTLVHQQGGMLDNIDYNIQSVHMDTSRAAEELTTAHEYQRKAGRRAACLMLILIVVVAIVLLAVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V942</accession>
    <name>A0ABQ8V942_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_475740</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="150"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="110"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4481332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="48383" checksum="6A94A0DBDE2AC289" modified="2025-10-08" version="1">MELESADCLASLVSSQLTLEEIRDITFARKGKAREDNPVTDEEIAFKLFEEENAAVVGSLRLAFSLQHALDVDQAILAKLSVEELGAVDDHRYAQALSLGQVLPDKSDAQEALEDSAVDSEATDTEDQIGERSASSGRPWSPHFGGSKPFRVHCIICTDSFRSSNTFQAPCKDYYCFKCLRDLVLACIGDESLFPLRCCQQSLPVADVLQLLPDDLRTKFENKSHEFGTLANNRVYCSTPICSKFLGSSAEAETSNIFCSQCSASTCALCKECSHPGESCAENIALLELKALATEKHWQTCPRCSSMIELKVGRYHMTCLCRMQFCYMCAAAWKECECLQWEENRLLNAAEARVEQEFGAVARVAEPAVFQRRVEQRTQELRYYHDCNPHRWRHHQGGGTCEECGNFLPLFLKGCRNCHIMVCVRCMRNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V958</accession>
    <name>A0ABQ8V958_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_842042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4480735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="14325" checksum="4DF9D751560B6A08" modified="2025-10-08" version="1">MSVAVPPGLYQVQVTSNASQKVAAPASAGGNITVNTSTSQVWQITGDGVITSFQTGSSATQARTPNVPAITGNNVVANAGTIAQQWIISGANLISNTYWTGYVMTSDGTRLFWGVDGSNNVLVTGTSAKTQFNFIPIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9H6</accession>
    <name>A0ABQ8V9H6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_904906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMA16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.170">
        <property type="entry name" value="Translation machinery-associated protein 16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021346">
        <property type="entry name" value="Tma16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038356">
        <property type="entry name" value="Tma16_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349:SF2">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11176">
        <property type="entry name" value="Tma16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="277" mass="32132" checksum="05025AB6077E0602" modified="2025-10-08" version="1">MAPSKTSKTSTKSSKKEKIFHPQSRKADQLSRKAQRKDKLVSLVSSRNKKHDILADFYGFFYHSMPAEGTLTLEELHSLIADVWLKRHDEELETERAARRKGRPKSVKESRLEDLTLRESEQYRTGFEVIDLTHPENVTLFRTWDQKEVPFIDLLRFIRICSASPNTFVVSRPGKHYSITKDLLAQSLPDSGDMELDTYKMGRERRRYDSGVSGTPINTHFKVHRYEREFKLINHAARELFVIFNAVGRTFLFWPILSASTCLDPHRFDTEGTILAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9J1</accession>
    <name>A0ABQ8V9J1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_773918</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4476173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="358" mass="40253" checksum="4C9C260E89776E0A" modified="2025-10-08" version="1" fragment="single">MSLSDLPCAPRKNNDPKQLGYWKLGRILGQGASGRVRIARHAKTGQMAAIKIIPKNLLASRAEGLNLAGAEAERQEQSLRREVVLMKLIEHPNIMKLYDVWDLPDELFLVLEYVQGGELLEYLSKAIESGQKSIPLSQALSYFQQIILAVSYCHRFNVSHRDLKLENILVDSDNNIKIADFGLASFQPDSIVRTACGSLHYCAPEVVTGYGNYNGPMADVWSCGIILFALLTCSLPFNPENDDDLKDEIIHAEVPFPTGLDSDAQDLISRMLTKDVQERITMSKIQRHPFFLSEKPKITYGGIPSLETISVPLKSVDDIDLELLRSLRTLWREAPDEELKNSLVNPDRNWQKGAYYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9Y5</accession>
    <name>A0ABQ8V9Y5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_525692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF11">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="17"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="486" mass="53623" checksum="838235A4D5C75D17" modified="2025-10-08" version="1">MAIDTIPHGSGDDVKPNIVVVGGSYVGSKVVDDLIPLVHETHNIVLVEKSSHFKVALAIHQKVQKINLSQNIFAFPRLHAVSGFESKAFIPYTSEYFDEAYATLSPHKTHRCTHIITGLVTSILSAEVILEDGRTIPYEYLVIATGTGQRTTLGLHNSNIVNSTLTKDTSNDKEKGLVHIHEWQADMKRANKIVVVGGGAYGVQLVTDIKTYKSTLSKNVTLVHSRAKLLHTFHHGLHDIVMEKMKEIGVDTILGQRAIRIEEVEGMFDDSNEILGVTRKTPEFIVHLSGGEQLRADLVITCLGGTPLSDPLRALAPAAVDLETGYIRVLPTLQIASPNDHNATSNSSYTAYPNVFALGDVAHTGAHKAARPGHFQSGVVTRNIQRLIKAKVAQRLNIKSKFNNHNNAQPHKGAHDVLESYIPPEAPGIHLRLGMRDSLIFRNPALESDVPYVQWDDRDSATFDCGCERYWKKRAETLWKNGDFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAD9</accession>
    <name>A0ABQ8VAD9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LSM1</name>
        <name evidence="8" type="ORF">C8R41DRAFT_840416</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4484085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="136" mass="15692" checksum="1F00DFEEADCA1259" modified="2025-10-08" version="1">MDSLIPFTTSGSLVDCVDRKMLVILRDGRKLHGVLRSYDQFANLVLEDTVERIYHENLFAESWHGLFLIRGENVVLLGEIDLDREDDIPLRQVEYHELEPFHKSAIELKKQNDDAKSHILYKQKGFCKEGGEGDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAQ7</accession>
    <name>A0ABQ8VAQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="26616" checksum="9E416BE6ADF60495" modified="2025-10-08" version="1">MKGSGEHCVKIHEDSLMDAWASSRVCQAVVVVEVLSLGGGFEDGSGVRRFSREEGEVPERGRRFLEAHRDPGQRTQFSLLPEQWRTIAAKIESSTSSTRALLELSLLNDQDRLEEDHLELQDFIRRQPQLSTIVEPILSDSRLPLVPAKVLLILKKRKRVIRMGEVPSSECKHSVEPDLGVGNADYRRVVLVLPPQAVSHPEDVEPRTPSRGDTPNKASHPLPSPGVSLPLPPCADTSYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBG6</accession>
    <name>A0ABQ8VBG6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NTF2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_838258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4486418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33905" checksum="6793F751CA46FA1B" modified="2025-10-08" version="1">MDIDESRNRYKRLSLAGESTLSVVSLHSTSLEICEMVYGEHSTSYDAVERFYEASARYENPLVTTTSRTMLTDILRISRQLSVINVPRPLAVVYSFFRLQIPDYLSSPWIHALRAWTEIDDICETESFDGHRKTIVEHTLNVLVFPNIHSDSGTPARFSHSTESAPSTPGSQIPPSHPIHPSLPIPGTSLTVPSPFHLKLRIITRFSFNEQGRITHHRDFWDVKDVMGLVPGVSLAQWIGTRLTARGLSYVSRAWFKTSGVQASSTENDAEIRLENGYGPSSSPAADYAKSTGKDFADSAVSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBJ4</accession>
    <name>A0ABQ8VBJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate esterase family 9 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_838381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF5">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="152"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="948" mass="102347" checksum="61458223839C2320" modified="2025-10-08" version="1">MEKAIITPYIQQRPSTKRPYSSLRTILALSLLVVCVYTGLFAAFRTLDTKSSVAKVPINAPQIIQKCSTLNVIPGPPQDFDSRKESDRYVLGTNPTLIKNATIWTGNVKGLEIILGDLLLDKGMIQAVGEIPGHLLNMYHHLSVIDANGSWLSPGIVDLHSHLGDQSSPKLSGSADTNSRKGLVQPWLRSLDSLNTHDDAYQLSIAGGVTTAVILPGSANAIGGQAFVIKLRPTKERSSSSMLLEPPFTFNGTGIEEVQPPRWRQLKQACGENPSRVYSGTRMDTIWAYRQGYEEARKLKVKQDAYCEKAVAGHWDNIGDFPEDLQWEALVDVLRGKVKIQNHCYEAVDLDGIVRLTNEFKFPIAAFHHAHETYLVPDLLKKAYGQTPAVALFATKARYKRESYRGSEFAARILAENEIQVVMKSDHPVLNSRFLLHEAQQAHYFGLASNLALASVTSTPAQTMGQGHRIGFIRKGYDADVVLWDSHPLAIGATPKQVFIDGIAQLGSPFVRPKSKALQHAPKTPNFEDEKKAALEFDGLPPLGPKESVSDVVIFQNFDTLFMDMGNGVEQVFAKDHLGAPQIAVVQNGKLNYIGVPEGYSTNLTTTPRTVDLHGGSLAPGLLSYGSRLGLVHIAGEATTQDGEVFDSLMDEVSSTLGREAVVIRAKDGLQFTTRDALLAYRSGVTTAVTAPYSSGLLSGLSTAFNTGAAHKLKEGAVMQDEVALHVSLSLSSSVSVSTQIAMLRRLLSGGARGDLELQISRILEGKIPLVVDVHNADIMASLIQLKSEIQEQTKSVIQMTFAGASEAHLLAREIGAAGVGVIVSPVRPFPSFWDMRRILPGPPLTQYNAISTLLANNVTVGVGVESDGAWAVRHTRFDVSWAAIEAGGDISREEAIALASSNLEKLLGLASGTVSSSLVATAGGTILDFESKVVAVASAKRGVLDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC14</accession>
    <name>A0ABQ8VC14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_455513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="260" mass="28410" checksum="89B9557C632658CC" modified="2025-10-08" version="1">MSFEITDVLRTWNTLNPQERNQLHRLSAEMTFHPLLIKDESTMRKLLAPALAAGSISDKDYAFAAARLGSLSNFYYFNYHHVGPAITAVVVCETGSLVLRKRPSAFIRGFFLFPLAFAAATLSTHSAIARRIDSIWEGLDNPLGVGKVIHARIRKNEQGVYSEPSSSDGLIPDFVSDTVESSFDGEPSKPLSSPEPPSPASPSSPSPPTQSNASNPNSRWDEIRAASKGQSAVSTWDEIRQQNARAQIPGTHDNQDRSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VC65</accession>
    <name>A0ABQ8VC65_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_845726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="44"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="2">
        <location>
            <begin position="131"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4476834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="31968" checksum="4E6997C4785D1F87" modified="2025-10-08" version="1">MTENRIVFYDIPLAQPNICWSPNTWKTRGVQDFSSQRPCDNMTHDARYSLNFKGLAYTTEWVEYPDIEALCIKIGAALTDVKSDGTTPEYTLPVIYDPSTNKVISDSFNIAQYLNTTYPDTPQLIPPGTRALQSGFTQYVNLRVKSILGQFVRPVVFQRLPFGKSQQYFRRTREALYNVKIEEWAPQGEDRVREWKRLRRALIESLDGHYREAKEETGGDFLCGVDPTFVDFALAGILQWSKHILAAESEEWNNILSWQEGKWANFMSRLERYAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCF4</accession>
    <name>A0ABQ8VCF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_836722</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="61"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="92"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="295"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="440"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="61"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4487431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="486" mass="54105" checksum="FFBE4DFB3C946E1D" modified="2025-10-08" version="1">MGNMGAGLHSVDWSRTTLEHFEKNFYLEDKRVSARSEREIEEFRRFKEIKIQGRNVPRPVTSFSEAGFPEYLMASIRAQGFKEPTPIQCQAWPMALSGRDVIAIAQTGSGKTISFALPAMLHINAQPLLAPGDGPIALVLAPTRELAVQIQQECTKFGSNSRIRNTAIYGGAPKGPQIRDLQRGVEIVIATPGRLIDMLETGKTNLRRVTYLVMDEADRMLDMGFEPQIRRIVSQIRPDRQTLMFSATWPKDVQKLASDFLHDMIQCNVGSMDLTANHNIEQIIDVCSEFEKRNKLISHLEKISAENAKVLIFVATKRVADEITKYLRQDGWPALAIHGDKEQRERDWVLGEFKAGRSPILIATDVASRGLDVKDVGYVINYDFPNNCEDYVHRVGRTGRAGKKGTSFTYFTTENARSARELISILREAKSVVPPELEEMAMLGGGGGKSRYNSSRGGSGRGGGRGTGSRYGQQSDTGYGSRSSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDC4</accession>
    <name>A0ABQ8VDC4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_954930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177:SF1">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4489134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="38392" checksum="920A27EFD5E4C9BE" modified="2025-10-08" version="1">MSVTVCMSVVSSMFTSMPDLDKRQLVFDEMAKDPNSKRGPQTIKECLSMEHGVHLTREFIEDTMREEDPEGFRLCDPTSEKIPRTVLVCIGPHQEWSGDGHDKLAAIGFPIWGVRDVWSGKWLGLWVVPNNRLKDTIGYLYLKLVHEYGGVPIQMTTDCGSELVTVYGFANALREELASNLPIDILPVHKFLQSIHNITIERGWLRLCLDWGENVKIYWDVGAGIYNPSDPQHNLKDRFNNHRVRKDKRKYLPSGVSPNVAFSLYHNYNGDLPEQAFCARASQDYGLQQVDRNVISKLMEDIGGEELIRFVLVDLDLPKLSMDNIWNVFQAMLPHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDK7</accession>
    <name>A0ABQ8VDK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MEMO1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_896614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="347" mass="38511" checksum="FBAA970CFA8EF998" modified="2025-10-08" version="1">MPRSSESSQTDLFFRIFESRLKAPESPVKLPTSHAGSWYTDDGEELATEISGWLDQVKGVHPPYPIAGCKAVIAPHAGYSYSGAAAAWAYKSIDITGIKRVFILGPSHHLYVDGCALSRCKEYATPVGNLPLDLEIINELRDTGKFEDLDIEADEAEHSLEMHLPYVRTIFKGVDVSIVPIMVGAISRQSEVVYGQLLAPYLAREDTFCVVSSDFCHWGSRFSYTYYYPEPKPSSEPGLHLSRAIAPSSSHPIHESISRLDHEAMDILTIPSSSASEVHLEFARYLSKTKNTICGRHPIGVLLGVLATLEENKEVHPTIQWVRYEQSSACATIRDSSVSYACAWIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDL3</accession>
    <name>A0ABQ8VDL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 43 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_835205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043750">
        <property type="entry name" value="DUF5695"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18951">
        <property type="entry name" value="DUF5695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045869778" description="Glycoside hydrolase family 43 protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="904" mass="98561" checksum="246674052BEB2951" modified="2025-10-08" version="1">MRSTFQHITCWLLLFAHSTFGQSNTLGLSDGFLSFNTSTFAVQLVKDSQTLYSLTTVDGGFNFIPSDMMADRANNGNYHLGDITFRARTVGSTAWTTGDTSTSRVKLTASSVSGNTRAAANLAPTLPRGSLLNITRQWVVDDNVLQLLFDVTNSQTSAVEIGSLGAPLEFNNIFTDRTAAQTNTLCSLFDPYIGQDAGYVQVTPLLGTLPPLVVLPVGQSPLEGWRFLPESTVLTPFYQSQTFEGLYEWDFHTLAYAEDEWASTTPWNAPTSFVLQPGQTRTYGLQFRVAPSIREIESTVASTGQPVAVTIPGTILPADQIGKVFLNTNTTVANITVSPAGALTWATNIDALTAGWLGYTITPHTWGRSRLSVTYSDGRLQTIHYYVTKGATAALDDLGTFLTTSQWYTNTSDPFHRAPSVISYDRSVNAPVTNDPRVWIGGLGDEAGSGSWLAAAMKQFVQPDAAEVAKLEQFVNQTLWGTIQNRNNATVKMSVFFYQPDLVPNYVYPSNEDWTVWWSWNQASAWATGRGYDYVHVTAAYWAMYRVARNYPSLVSVHDWQWYLNQAVLTVATLTDGQVGYADDGLMGETVIHYLLNDLQREGLTANATLVQSKMKSRWQIWSTERYPFGSEMAWDSTGQEGVYIWSTFFNDSVTALNALNSIIAYQPVVAHWGYNGNARRYWDNIYGGKLMRIERQIHHYGSGLNALPLIESFEANPTDYYLLRAGFGGLSGPLSNIDEEGFASASFHSFADTLAWDAYSGDYGPNFSGHSMGMGTFIINHPDFGWQAFGGNIVATSPAVQVQIKDSVRRRVFIAPLGALLSLDSGAFSTISYNPTAKTVTVTITPVADGTTGAASAPVGRLVIAQSAPVAGEGLLKPTSSLATDAGAFVIPFTNGAGTVTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VED6</accession>
    <name>A0ABQ8VED6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046383399" evidence="1">
        <location>
            <begin position="26"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="212" mass="23064" checksum="03266DD62BB3816D" modified="2025-10-08" version="1">MFNLSLLRLLATFLLLPLSLLAVTGAPLTGRTDMPTQLNPKRFGKITIRYTNCESARIYIGNSNSFLPVLQDGRGATGAGGNNNSEIFIGRHLLDVRCEVKPIAVVDFETVKRNCVYTDLKTLHGSSKWDYIAKAMGYLQQKEGLRFTFENGGEEKWIGLLEKCGGKQEPKTSMVHSSTAGSGCDNPVSQKKLPTLSNILIGGKVGNVTNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEH0</accession>
    <name>A0ABQ8VEH0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase pc-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_883162</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4491674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="585" mass="66853" checksum="60E4F5C7CEDBA477" modified="2025-10-08" version="1">MTIPPGLSFLFRLVFPRILSSIAVFGALTVLSGQRPGFSAYSTWIYLICAIFVHPVLFLVQTKCAEVLDNRRAAVLGAIQPPAVQGSSYELRSAIIQSFGHGYTGDCYFEWMNQYGYTFRLKIYGETRLMTVEPEHIKAFLATQFENFEKGPVTFDQLHSLLGLGVFNSDGERWKTHRNMTRPFFSRNRISDFDNFERHTENTISTIKARLTQGYPIDFQDVVARFTLDSATEFLFGKDVGSLGANLPYPENSPLANDPSILNHPSNVFVRAFMQGQIHTAFRARFGMLWPLKEIWSDKVSPYRQQVDEFVNPILEERKQHLAAEKPSDDDEGETFLDHLIKHTADNQVIKDELVNILVAGRDTTASLLTFCIYVLTQRPDITERLRLEVLEKVGPNARPTYKIISEMKFLRAFINETLRLYPAVPFDGRTTRSPVVLPQTETQPAYYIPAGVKCLYSVFLMHRRADLWGPDVLEFDPDRFLDERLHKYLTPNPFIFLPFNAGPRICLGQQFAYNETSYFLIKFLQAFTDFQIAWDVQPESSKPPASWKPAPGTTKGLDKVLHATHLTMNVKEALWVRMKDSNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEY8</accession>
    <name>A0ABQ8VEY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Surfeit locus protein 6-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_921200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029190">
        <property type="entry name" value="Rrp14/SURF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029188">
        <property type="entry name" value="Rrp14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007019">
        <property type="entry name" value="SURF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369:SF0">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15459">
        <property type="entry name" value="RRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04935">
        <property type="entry name" value="SURF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14 N-terminal" evidence="6">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal" evidence="5">
        <location>
            <begin position="193"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="191"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="248"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="358"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="418" mass="45929" checksum="22B61FB4B9861E3D" modified="2025-10-08" version="1">MGSTTTSTVTVTPLSTLRTSLEKHNDTFETLLKLIPAKYYIVQEFTEEQAASKFQQNKKKQKAPKQAIKEASKKARKDKLDPANQKTIIDIQNESSNVKGKRKAIEIDSSSDEEDDGDDEVAMDVDVRLEEGIDADSPPTPPALVPMSTPTSITALRAKLHAKMASLRRGGGGASGANKVELGARLETGSRDDLLEERRQQRAAMRERRRKETKEKIKRDNTNNNNKDASAKLTKTQLLVNDPTAAIIASQNPNSKLTHVSFSGLSSKPQPSSSSNPTQALSQLVSHNQKVASLPSSKQKAIEEKERFEKASARLEGVKVLDDEARLRKAIKRKEKEKGKSKKEWGDRKEKVEMAIKAKQKKRGDNIAMRNERRSEKRKGIKAKKGGAHISKGSQGGKARPGFEGKAFGKSGGKGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF91</accession>
    <name>A0ABQ8VF91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_884361</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF6">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045632059" evidence="4">
        <location>
            <begin position="24"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="89"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4486918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="481" mass="49527" checksum="3D751C2D0C258D3E" modified="2025-10-08" version="1">MVPFSSLSPLALLVSLSANVVYAAPRSSPLSLSMTLSRRAPEARSPDEIGSWAQAHKANVETKYGNPSSKAKRSSGQNLIVNQKADSSFFGSVAIGTPPVAYDVILDTGSADLWLASSTCTESACEGIATFDSSSSSSFQNKSTEFSITYGSGDAAGTLGEDIVQMAGFSVSNQVFGVCDQVSDGLLNSPVSGLLGLAFQTIASSGASPLWETLASSGAWDQPLMAFQLTRFNNDSKATDLEPGGTFTMGATNTSLYTGDIDYNDIPDNEESYWLQTVSSITSQGSAITISSGSSALAAIDTGTTLIGGPADAVAEIYSNIPNAEAGTGQLEGYYIYPCSTTVNVTMAFGGKSWAISNADFQAEQLNEDTCMGAFFSLTTGNNAPAWIVGDTFLKNVYSVFRYNPASVGFATLSAEALAMNGVNAAVPSATIGSAAATISATATAGTRDANGASIIQSLLSGPALSLLVIAMTIVFSSVCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFD5</accession>
    <name>A0ABQ8VFD5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_765923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
            <location evidence="7">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4491820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="387" mass="41456" checksum="9E1F7B969CC99CC4" modified="2025-10-08" version="1">MPEVFSISQNPITAHAFNADRSQLAVSLNSNDAQILIRSGPEWVPTEMLTEHDKVITSIDWAPNSNQIVTASQDRNAYVWQQTPDPETGKIVWKPTLVLLRINRAATHVRWSPKEDKFAVASGARAIAICSFDPENNWWVSKLLKKPIRSTVLAVDWHPNNVLLAAGSADMKARVFSAYIKEIDERPAATVWGSKLPFNTICGEFTSAAGGWVHSVGFSPSGDVLAFASHDSSISIAYPGGPVYNIRMPTLPLVTLTWTSEDNIIAAGHDCQPIVFGGSDAGWQEIGTLDNGSYAAGSKAGPGSVGRLKAGAFATFRDADSRGQTSSGTTDTKLSTIHQNTITSVRPYAGVPGQITQVSTTGVDGKLVIWDTASVSALTGRMAAMSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFL2</accession>
    <name>A0ABQ8VFL2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_832603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="270" mass="30158" checksum="C9650B1311BCAAEE" modified="2025-10-08" version="1">MAISPPACIHSSSYKMWTFDNTFAEEIAVLVSQWDHFCPAAALFYWGKNSLDTGLRIEATEIMREFVDNIQFGRDPEGWLFYGSPQDLDTDSGDTVYYRVYINDESPMAIRIDFSGRDPNTPGIKPFAQFLTKDTVKIPIEDIPADTGSGLWRKLNTGISSATVSKLTNDPSIKLSAHAIGKKLTFDLPNSASFTQALHIDGAFHFQNIKDLNYNTLAITNYNTDRILYYDQNDSTKLLGVFYPSSDLFPDGFNNEGDVNPPIATCSDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG53</accession>
    <name>A0ABQ8VG53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-galactose transporter homolog 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_335108</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4493234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="402" mass="44131" checksum="6D8EB4282DBD72FA" modified="2025-10-08" version="1">MSFIRLIFCVAGVYSMFLWWAIAQERLSVPFQSIDGESSAKFRSALFLGTCQSFLSSLSALIYILIRKKPSETLIQALGFHDKNSGEPTSASTANGKAHTHTHHTNGSAKPRPDTRFSSKALLLSYAQCATFITFAAPFGFAALSYISYPAMVLGKSCKLVPVMIMNVLLYRRRFAPHKYLVVFMVTTGITIFMGFGSDSQKHGGKKAVSASMDHGSMPYASLIGASYLLINLALDGAINSTQDEIFSRYKISGQQMMLWINLMCTCISFVLMVLPLPSIPVLLPSGNGRSELVAALTFVQQHPGIISPLIEFSVTGALGQLFIFETLQHFGSLTLVTITLTRKMFTMLLSVVVYNHQLTPGQWLGATVVFAGISVEAFVKRNDVHAKRVLQEKEKAKLKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGG1</accession>
    <name>A0ABQ8VGG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ESCRT-I complex subunit VPS28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_369600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="7">
        <location>
            <begin position="117"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4491845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="219" mass="25010" checksum="FEC5EA0204980A3A" modified="2025-10-08" version="1">MSSSFSLDEEVRLYQTNAEREKYNSLATLFGIITAIHYLENAYLRDSITAAEVRKRYSPACSRLLSQYKTMLKLVGDDVPSVEEFMKRYRMDYSAALERVKVGVPATVEHPTDSGPETAKWVAETTQSFITFMDALKLRLRAKDQLHPLLQELVTGYARFKGSKDWEGRSRMVGWLITLNGMKASEEITEEQSRQLLFDVDHAYAEFFRSLSGKPSDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGG2</accession>
    <name>A0ABQ8VGG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_919647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4493183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="510" mass="55739" checksum="1EF7D17531525D46" modified="2025-10-08" version="1">MSVVERLCSAPAVTGGRLLPQEQYGRRMSSSVPSTCIITENPDIAGIGVRLSIYIPAILVTLNSGFVTGQVFVDIFTGKLSEYIPPAPPKPSLGDANSVSGSDIELADLEAAGHADRSSSPARTTSSSIPSWTSDNSALRTFRGYLSYISDHPHYFESAKSLERSLFLIGSAIIVSAFLDARGVTSTIGLPPYHALLVLNLSLLNNLAGSSFLPFRIGAIFATIEVDDEDDEHTKGIMSKTIWWSIKFFDVFGLGLLQTGVIIAFGIWFWVSTMFYHSFSGYSMTVDALLSSPLYNSTVAVSSSGSLDPSQCVSKTFYWAFIGSPIESTLSLQVISFIFYVGTASVPFLGIFVTVVPTIILFRTVPIFLGLSFSSVIYSFGIILPRITPRLIYILLPKLFHLPITLSYPHPTQPLFPTRLSPSAISTKLIFFAMMITNQCTVVFLIISTEKTISMNSASQKGMVVINGAQWTYGQTLALMSAVIGVLMYAAEVVGHWREAWIERRKRMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH60</accession>
    <name>A0ABQ8VH60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_310714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="15463" checksum="0FCD9E1EAD31E172" modified="2025-10-08" version="1">MLFKLRRKESPWEVAERKLVDPVLMYEEEELDLDIVNQSDICGTYVFDVKKHDQSEADLRNAVVIARQQLLQEIATKGLNVLLTESWNLTVYRQGKRRRIEVRYSGRPAHACGKLPLIHPPPFMEVLRDCLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHH2</accession>
    <name>A0ABQ8VHH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="331" mass="36372" checksum="74A9BB20AFA18B90" modified="2025-10-08" version="1">MSAPTTPSTSSARRTRTLHSIHQDHNILVALLEKDVKGVSAVNKEMQKAKVGVDAANIRLEEKLNQVELDIKEIWKLTSPPSTPTCSWKVKHIPSLKNLYATPRSPLPAMSNTRSAERVIASPSKQNISLVWISLEDEANCPDDSEDSDTDDSGDGWIPQSAADVSSDEDEPLPGLGGVTAAEASARKASKSGGFVEKTYLVYYGRNNSDGLYFKWQGTNGATGALELTDEFPDAIHKSFSNRKLAAKAYKECKHTGVLDILKIPVHAKENLIVIKGENPGVYNRCTLMKQGLCWHGGKVIIHIGTRYDAQQAFLVLKNNHKTYELPKDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHH6</accession>
    <name>A0ABQ8VHH6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_866846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="103" mass="11942" checksum="FEBEF096D85CE8EC" modified="2025-10-08" version="1" fragment="single">MSYISLPYPTLPDVPPALVEDLNNSHRQHLKLHAIYGEESRKTRQTTKLISANIIEQWAKPWIKIWMEDEAKRNVILDWLAQAICVDFEQIPSEGLNVFLSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHY3</accession>
    <name>A0ABQ8VHY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Smg-4/UPF3 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_828426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12455">
        <property type="entry name" value="RRM_like_Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF3" evidence="6">
        <location>
            <begin position="57"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="533"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="542" mass="57939" checksum="4B7512B22CE6B4AD" modified="2025-10-08" version="1">MIKAAEMATPAGILTQMTSTITPAHSASSPTKSKKDRVRGEKGKDKERKDKFPQHEERLKTIVRKLPPNLPEEIFWQSVQTWVTDETVSWKIYYPGKFRRRLNKENVPSRAYILFKNEGQLALFSKEYDGHLFRDKSGNEAHAVVEFAPYQKVPPEKKKLDPRNGTIEKDENYISFIESLTASANREPVSIETLIASTQPVPQPKTTPLLEALKAEKNAIKEKAAVKEKVAIMRNAALEASRKEDSGKKKGGKTGSDPSASSSVLPPSSKKALHKKAVLNANNTSTPTAGGPAAKSGGPPSKSSKASRQQLSQPQTRTQPSVQPPTKLLTHNPPVAPSNPESQSKTDPSSSTAPTPAPRRVRPMLGLASRQFEAALSGAGVNAAERKSRKEREKEREAAAVNKDKEHGPQEQALALVIGKDAPSISTNIPTANTNNTLVSSGSKPPSPKRDRGGSKRKNSVSSNSGTPIATTPKVPSILQRAVIADISTGSIPPVIPPRGGDESVSGPSSSVEAGPGIRGGRRGRGRGARGASNSTTPGRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHZ3</accession>
    <name>A0ABQ8VHZ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_920855</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046538358" description="alpha-1,2-Mannosidase" evidence="12">
        <location>
            <begin position="24"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4488614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="544" mass="59853" checksum="B9E16FE3F7FE543E" modified="2025-10-08" version="1">MVQFSRPLKVALAVSACVVPALAGQVQLSNLQLPPSAAATQATVKEMFVDSYNAYRTYAWGHDDLLPVSASFTDGRNGWGASIVDGMATMYIMGLDDFFNEALNFTQFINFNESQVVETVSIFETSIRYVGGLLSAYELSGKQHQILVDKAKEVADKMAYAWQTLPDQTIPFGEIWFSDNTAVVDTSNIAEAGTLDIEWSRLSLYTGNDTYTELTEGSVRTIANLVTPLPGLAPQGIDPSSNTFVGDYLTWGGGSDSYFEYLIKYPRVTNTDDNLFADTWHAAVDSSISAMARKSTVGNYTYIADWDEGELIHVGSHLECFHGGNWIFGGHLLNNQTIIDYGLELVDACWNTYASTSTGIGPEVFYFLANDQWNGNGVPSEDELTFYNEHGFWITTSDYILRPEVLESNFYAWRSTGDTKYLDRAASAVESLKKYLPQPSGGYAGLNDVDDPSAGFIDDQESFWFAEVLKYLYLTFDDPEHISLNDYVLNTEGQPFEAPAAKDVYGSGQPAIVLGQFVSKTGLPLPAISPNKYLPSPLPTPTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI09</accession>
    <name>A0ABQ8VI09_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_830998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="141" mass="16597" checksum="4F7511E9F8510AAA" modified="2025-10-08" version="1">MQPLWCFDLYRNIKLLIKLLVSAKSLVWVTCLSRDSIFDLHKWHLCLIAQRWVCTTESFRRVVHSGRVNVDWIYTGMLEIGVVVSSILFGILTMQIYFYHKNFSEDPPWIKLGLVDGIWFIELIHTVCIAHEVYEPITQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIR6</accession>
    <name>A0ABQ8VIR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Pre-mRNA-splicing factor CWC2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_762410</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM CWC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12360">
        <property type="entry name" value="RRM_cwf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034181">
        <property type="entry name" value="Cwc2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="16">
        <location>
            <begin position="86"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="151"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="13">
        <location>
            <begin position="86"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="277"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4495543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="42465" checksum="A420359B1243BC85" modified="2025-10-08" version="1">MSSNGTETAVVAIPPKKTKIKKLRPARKQVKPGDVEKKETPQTGKEYNIWYNKWAGGDREDSYSNKTKSQTRCNIKLDSGLTRANTTGMKYCCLFFSRGCCPYGWECEYLHTLPDPSTALPDSSKDCFARDKFADYRDDMGGVGSFNRQNRTLYVGRIKETGTGLETEEVVRRHFKEFGEIEHGWAVKVLQYRSVAFVTYKSEFHAQFAKEAMACQSLDNDEILNVRWATEDPNPVSKVNEKRRLEDMGQAVIREKMDPRVVDAMRTIRALEDGDVLDEDGNLLENGPMDADEEDDEGSDRGAKRRKLDVDDRVSISPPPQQEPPKLTGLLSADTMDSLKYFSEIRKRNGIQPSTAVRITKPSAGLGLGDYGSDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VIW0</accession>
    <name>A0ABQ8VIW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1941-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_895196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040144">
        <property type="entry name" value="RAP1GDS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10957">
        <property type="entry name" value="RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="84538" checksum="6D2835B93E374CB9" modified="2025-10-08" version="1">MANNLLLLEKKLSELLKNLQDAESDDTWQQVAATAQVLANGLRDKDGSIDNHTILGRTSIFTNLRALLSLALHGSTIPDSPYTSPILEILRVSANLCMDHDDNRASLLDAGFPQVLLSLLEAYTSLVNSSSESQQLLSLSLSHLKVVRTAVGVLLNASVGYDPVKIRLISLDAGSTLLKLLSVVYIPGAWLSVSSPDAEEWQIRSMLSAWVWRTLVELKEVKDETLQPLSAKDLPLLTAILVAFTPPHTSTSSGTFPSDSEMFFDLVQADLECLEESCSLIESLSLDVEDVRLCLALGFKTPSEHPTGSSLRSILDFIEKGEYSSLWANAPDDFDVPRKQKTFDMCKAALIKTVVEVAGEEAAEMSLWDDSEGRAGGEFVVRMVEWLKGYVIDIDAGKGAFFNRSDLATCASLSLGNLTRREKNATVLLSPPHSLAPALSSQHLLSISTDIKVKHGVLGLLKHIAQAGPPGSDIHVILGKAGLIQSICDSGVWDEKTDGMAEVLQVSAIGVVKHMCNTNVENTFSLVLPPSTNTPIPPSGLSLILALVKRADTVTVKSEGTRVLVNVIKSLWSGDIIGTPVTTASSPIANGTVDSDLLAGKERRKKETVKAILTMQCATALASLVGRSGQYPLLINEGVVALTLLSTQKAGAPLVLRAILAPLSFEHPPSSAEPPSASTSVTTDSSSPTIATPSTRGRLPVPKTPLDMFIAVLKNVDNPINYQPEVRINVCSFFIQIGRNIAGEEIEKIKETVRPVMEKVLKTLKDATGKEEMLGNALKKALDTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ87</accession>
    <name>A0ABQ8VJ87_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="13">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_909531</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. PP-2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07416">
        <property type="entry name" value="MPP_PP2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041751">
        <property type="entry name" value="MPP_PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="15">
        <location>
            <begin position="174"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="553"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="563"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4496457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="656" mass="72358" checksum="44796865827297D8" modified="2025-10-08" version="1">MSTHLARAIEQISVKPPLPDIDFTQHTLDDGTTVSTQERVIKDVQAPAMQIPTPEQFFANHGQDRSKPDVGFLKNHFYREGRLSEEQALWILEKGTEILSKEPNVLNVDAPITVCGDIHGQYYDLMKLFEVGGSPADTRYLFLGDYVDRGYFSIECVLYLWSLKIWYPETLFLLRGNHECRHLTDYFTFKLECKHKYSERIYDACMESFCALPLAAVMNKQFLCIHGGLSPELNTLDDIRVLDRFREPPTHGLMCDILWADPVEDFGTEKITDSFVHNHVRGCSYFFTYQAACQFLERNNLLSIIRAHEAQDAGYRMYRKTKSTGFPSVMTIFSAPNYLDVYNNKAAVLKYESNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLVAVLNTCTKEELEESDEEEEVVSPMTSAVPAPEESDQRRKVIKNKIMAVGRVARVFALLREDAEKVSELKSISGSSKLPYGTLASGSEGIKNAIKGFEDARKSDIENERLPPDLYDAESEEGKAIIASGSLPSTPAEGQEAPTPITANGVAASLAAAISSGAIPSSPSPASPSSASPVSPTSPVSGGGAFRRGHGRQASLGTTMTSPSTRRRSLESTMSLIQGVLDGKDGTIPENDETVEGLAAQLAGSSVNNGATAAGFKSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKU5</accession>
    <name>A0ABQ8VKU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(9)-N1)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA methyltransferase 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1G9)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_760857</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="10">
        <location>
            <begin position="55"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4496906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="321" mass="36868" checksum="19419814A1F14DB7" modified="2025-10-08" version="1">MSKKAMKKAAKAERYQAFKLERRAREKQMQKEKRRLKAQKRAAGELDDSAELEEKARKRQKMSGFGGKIVLDLSFDKLMSEKEINSLCSQLAYTYSANRNASYPFTLLCTSLNGRTRDRLEAINDGAYKRWTHTEWWENSYDCLWSSPGVSSSTREASLPQADLDVQKQKIVYLTADSGEEIEELKPGETYIIGALVDRNRYKNLTFDKATKESIRHARLPIGKYISSLPTRKVLTVNQVFEIMLKWVETRDWEEAFNCIIPKRKFLDSRKKGKDKSLSEKEEVVSEGEGGDITSDQAELKIDAEDLEKVVQEDQLLEAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKY0</accession>
    <name>A0ABQ8VKY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_760665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039295">
        <property type="entry name" value="MSB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778:SF1">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="358" mass="38337" checksum="976355EEBDC1F665" modified="2025-10-08" version="1" fragment="single">TTTVVSTSVTTALTVVSVPSDLSFVLTQTTLEVASVSSSATSQTLSNPDQATTTISQTTLSASAPLATAALPSSLPYRILPQDQLASNEDLSGYTLVSLLFDLQLNWPFVVSSPDSSSQLFAYMPVILQNSLGLTADQVKTWTLQVNIPSDYTGPSDADLLETMYLVYIPSSSVSSLQDQIKAQQSAFYTGVNNSVAQQLASLVNSGWNLLSIAAPDDSGSTGSSSSDSDTGASSSDNKSKEDAIIGVTASLGGIAICVLGFLIYRSYKRRKELAHRRLSEPTGTAGYRPEGREFDQDSVGGQRRRSFYFAEDSLRGYQGDRVDDSHFDARTGQMSQRRNVMPAAISAPILRESSMNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL24</accession>
    <name>A0ABQ8VL24_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_823276</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033865">
        <property type="entry name" value="Ataxin-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006155">
        <property type="entry name" value="Josephin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159:SF0">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02099">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01233">
        <property type="entry name" value="JOSEPHIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01246">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50957">
        <property type="entry name" value="JOSEPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Josephin" evidence="13">
        <location>
            <begin position="8"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="176"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="238"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="319"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="449"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4497107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="477" mass="52435" checksum="B1000DBE1FC08530" modified="2025-10-08" version="1">MAGLENLLPLIYHEKQQPGSMLCAQHALNSLLQGNFFSASDLSAIAQNLDDLEGTYDTENPSFTSQNMDDTGFFSVQVLENALDVWGLSLLRWRSEQMRPYQDYPEQERAFIFNSQQHWYTLRRFGVSESYQDGAGSGHWFNLNSSLPGPEWVSKLYLSMFIQAAETDGYSVFVVRPTDPEAPPTLPKTEADDVASTLPDPPGAQSVTPRTHDADAMGYEGMEDEDIELQMALQASLGHDIPPSPADPPQLLRTSVPLPLVDSYPPSTSGSGTRTPLQQDSLLSPISPDVPHDPASVEASIAQSRRIYERMLAEQNLAHREIAAEGGGNSRVRRMREEEEEEEEEMLRRAIAESEAMAKEEGHEMGSISDDEGESHVNLDQSHLAPSSTAGRRVYDDEDAELQAALRASLEGWNPPPETTTVPAPAVSHTSPLQSSDSSMTDDDESIASEDTAAAESSEAPVSVEEMRRRRLARFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL62</accession>
    <name>A0ABQ8VL62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_764638</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="204" mass="23986" checksum="CD5A21869DEFFF3C" modified="2025-10-08" version="1">MKVEIQNRFRQIPTFGFDTIRLFSNNASEMKRLAARDFEDLLQASTSNMFGCAIPVFEGLLEGDDNKMLMKLLYRTAEWHALAKLRMHTERTLDYMETCTQEFGKLMRDFRDLSQKFNTRETDREMTARYRRTAEQAKKSLGQQASGPPLIAPGARRKKTLNLFTYKWHALMDYIWFIRWFGPSDIYSTQLVCELYSEKNGTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL81</accession>
    <name>A0ABQ8VL81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycerol-3-phosphate O-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_273751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="3">
        <location>
            <begin position="52"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="708"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="712"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4495564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="781" mass="86894" checksum="92F369F1669887B3" modified="2025-10-08" version="1">MVDMAAATPVKIDSSHLSYEASILFWKLIVNIFFREIRPRGAFNIPRKGPVIFVAAPHNNQFLDPLLLSLQVHRETHRHVQFLTAAKSLNRQFVGLFSRLMGSIPVARAADDAKPGIGRVCLSEEDPCLVIGEGTQFTAEFAPRMQIMLPKTVNYATAEVAEVVSDTQLRIKKEFGGDSGKRTAKVKEKLAELRRDGQVGLEFKILPYVDQQQMYQYVYESLRHGGSIGIFPEGGSHDRTDLLPLKAGVSIMALGAMANDPECHVKIVPVGFSYFHPHRFRSRAVIEFGSALDVPTEFVEMYKQGGVQKREAVSKFLDLIYDGLKTVTVRAPDYDTLMLIQAARRLYKTPAQHLTLGQVVELNRRLLEGYTHFKDEHRIQKLRQDVLKYNRLLRDLGLRDHQVPRAQKANWKTLGLLTYRVGLLIVWTIFALPGTILNGPIFILASILSRQKAKEALAASTVKLKGRDVLATWKVLISLGVAPVLYLLYAFLATLIAIRANATTKWKIMTPLIVFMALPFMNIAALKFGEAGMDVLKSLRPLVVASVPGQQRTLDKLRAMREQLSNEVADVINDFGPKLYEDFNQWRMLPSASAPPSSGTPGLWRRKSSTGAVDAQGLGLIHPMTWIDERLFGWSRSAHRGTSAWAGSFEEPSHTGTPEDSDEEDAGDYDHVIGLVPGHDDHLGSKTRSRNNSYANLQRLRLSSLAQTTGTDVPSAFSPSSPDDDGLQIRTGHRARRESLSDGVPVQRLAAVDRREPFSDATGDLNEEIRQGKNGQPNNIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLZ6</accession>
    <name>A0ABQ8VLZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FUN34 transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_894680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4497296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="25704" checksum="6560C2B87A3E8CEB" modified="2025-10-08" version="1">MSSAASDPEKGRVENITSNGGTGRTRVSNDVEEYGPNSGDPVSYQRYPSHIANPGPMGLFSFASTTFILSLFNVGTRGISHPNVVVGMAIFAGGLTQFIAGMWEFPRGNVFGATAFASYGSFWMSYATIFIPGSGIMAAFSDPQELNNAIGIYLIAWFMITIFFLLAVLRRNVAFTVLLSCLSVALLLLAIAEWGGMEQVQKAGGVFGIVTGLVAFYIGVSELLVAEPRAVARLPQGLLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMU9</accession>
    <name>A0ABQ8VMU9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_821705</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="835"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="870"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="921"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="948"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="976"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1065"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="386"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="645"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="764"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4497596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1091" mass="119433" checksum="1E3B79CA8EA73F6A" modified="2025-10-08" version="1">MYNNSLSTNSWAQTSYSISNLSLATRPEKCPPCFNCMLPAFTCGQYGDCDPYDGQCKCPPGWSGIDCLTPQCGSLADDQRIPRDDGQKCDCKDGWGGINCNVCKTDQACRGFPLFGIPDSEQDGSEAQNMTCYTGGETVFQNHQMCDVTNRKILDQVGDNRPVQVTFSCDKNEATCSFQFWVDEIESFYCGLDECSSEITPGYDFNTTSYKCDKLQCKCVPGRFICGQDGSVDISDFLTEEIKGPASFSCTSGGNTGSGPSFGGDTSNNCKFSEAAMNQLINDVFGDPYITLTCDGGECLHYSQVPGYVRPPKPDNTRWVALNALGACLFVVLVALLLWYVGRTGSGGDYGFLKKGSGGGIRLPESEEDSENESAKLMAEHVPASMHFDDLSYVLNSKTILSGISGAVKPGQVMAIMGASGAGKSTLLDILARKSKRGTVGGEILINGRIVGDAEFRAVTGYVDQEDTLMSTLTVYETVLYSALLRLPREMSEDAKKFRTLETLNELGILGIKDMRIGSSGHRSISGGEKRRVSIACELVTSPSILFLDEPTSGLDAFNAFNVIDSLVSLARNYHRTVIFTIHQPRSNIVALFDQLVVLAMGRVVYSGVVGRCGDYFDGIGRPCPAGFNIADYLIDLTVQSNVESRSTSPTLENSSSEEEDTSNGPHGEQTVLSGINISRDDSTELQLQTRAHPRPSSVISNSSVSGAYNSIKRKTSQLFEVVSYGNASSSSSQSQPHNHHGQMAAKLRYLVAEYKKSDVAKEIKEDRESVRSSVENSNGDNANSASNAYEAHLSQLPDVATETTLLRGRKRASWGTQFRILSGRAFKNLYRDPALLMAHYLSAVVLALFCGVFYHNITNDIAGFQNRLGFFFFTLALFGFSCLSSLGLFANERILFMRERSNGYYSSFTYFSSKILFDILPLRLVPPLMFGGIVYGLIGLVPTVGTFWKFILALVLFNLTTASVVLWLSIAFESVSVASLVGTLIMLYNLLFTGLLINRETVTKALQFLHTISFFHAAFEALAVNELRYLSLKEHKYGVELDVPAATILSTFGLRAQSFWWPNIALLGIFFGVFTVGSFLTLHFFVKEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMX8</accession>
    <name>A0ABQ8VMX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045160664" description="SAP domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="68800" checksum="DCEFA676CA29759A" modified="2025-10-08" version="1">MDWPVLCPSFRLSFSFILPPFTLLTLGVPCSSIDNGGAAAPAAGSLDSLIVSASNNLDPQFLVLLHKILSSQSLALSLLALRSQQLVGLMEIHNTSSAPTDHVAIELEGQTIEVRYPAEPQPPNSLIFPGEYTDGVMHTVYKDINNLKREALLALCKQYSLGTLGNKSVLKQKLIGFSENKIRWPSLIHGARRAHRGVRDGGITKNKPKPKDSSVASSTAVKKLKPSVIRQNELLGLPLNAPLGSQLFDTQRSKDTRTLEEKAELLRWAKEFDESHPYIPEAEIARRRKAREEERAKEKAAGTVMVTESIRSMNEQIANLTATINMLVVGLPTLPPLPATVLAQLQTQPSIPPAPFSSATSSVQTNRFSLGQQVHPVTSSHSVCTSLDRQVHPVTPDPIPFLSPPSTTPMTTGALASNSTTATSATPTNGLVIAGATEETTFSLAIGHGQIIRYKYSDIREPRQISFATNIVRLDRVWDDESLNWDPIDCARNLLQINGTAIALRYWQTVFSGKKNRVWSWLKKLWTEWKYVAERYRSRGPDDFWQEFSLTKGEHFHWKAITDPLRELRSAQDERLVDRAKVEYGDRFSQVFVNNRGKVLTDKSAIARRYLAELDRCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP65</accession>
    <name>A0ABQ8VP65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_894883</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039730">
        <property type="entry name" value="Jlp2/Ccd25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049">
        <property type="entry name" value="DUF814-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="126"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="210" mass="24043" checksum="AECDC19E8B6FDDB8" modified="2025-10-08" version="1">MVLFFTSAVVSPAATIYMGRDKVENEELIKYAWPQDVWFHVDKLSSAHVYLRMPEPMSWEAIPEVLLIDCAQLVKANSIEGNKKDNLTIIYTPADNLKKTGDMAVGQVSFHNDKRRENSIVNRLTKTKIERQVDHEQERVDRIKKESAIRRAAVAEKKKAELELARAREVEKAARSYDSLFNGEYNDGEDDDKPAIGARKTGRELEEDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPN0</accession>
    <name>A0ABQ8VPN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase C15, pyroglutamyl peptidase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_757270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="entry name" value="Peptidase C15, pyroglutamyl peptidase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402:SF1">
        <property type="entry name" value="PYROGLUTAMYL-PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35263" checksum="DC24E8E84DF6CB72" modified="2025-10-08" version="1">MPALSTANGGGEEGVFNVLLTGFGPFQNHTAENPSWLAVKPLHNVVIPLDSDPVVIDGQVVMRTPTTSSKHWLVKISALEIPVEYEAVMDTVPKLHLRPPVLPDEVKDDFYPLPPDKGYDFIFHVGVAGRGPLRMEKLGHKLGYYMKDVAGKLAPIVKGPPSEFGRRGIEDTDVSVVGEQPLQVGERLGLGFEMENAGDSYSARPSRGFGVGYEKFSDEIYTDIDVSRLVYDLRNSGIEQIYSSMDAGHYICDFTYYCSLAESKRNGKPYEKDRNTQVLFVHCPPVGQPLTTEEVTEAIRRIVFWVCSELAEIHDMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPQ5</accession>
    <name>A0ABQ8VPQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_894108</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF25">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="5">
        <location>
            <begin position="38"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="239" mass="25588" checksum="ED2CBCCB39EA94E2" modified="2025-10-08" version="1">MPLLPTRLSAPDQMAFSDPVAGIVEGFVARDVHRKELVVALRGSASVADVLLDTQVQLVPLVSPGVSIPHDVQVHAGFLTAWNSVGVQVLAILAEQLVLHGDIKTIVTSGHSLGGALATLSAISANQRFPQCRVITYSYGAPRIGNKAFAEFANKSLGENAFRIVHTHDGVPTMIPQSLGYHHHGIEYWQEYEPAIAENVVKCEPQGEDSSCSLSIPSGGVNDAHMKYFGIVITTPFCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQB7</accession>
    <name>A0ABQ8VQB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="312" mass="33796" checksum="313BC30B346B4AAB" modified="2025-10-08" version="1">MSTPPPSSMSTPGPSNSASFSSKSSKSSNFPRRQSLLDPRASAGEKGRMISSPPPPMHMIRVPSEETRVLARAQQQTDFKSSHPNYPARGSVVLYRLDDPTQDVLNMRDVEALLPPNLPFGSGGGGKSRQDRSGSGSMTISRSSMDGVGSVAGSMRSFSSRHSVMSGDSRIPLIRSDFRDGSHRKGQEMQLVAYAYQPDALLDGEDDGEDDDWLHDPKVSFYASPQSKAEVRENKGKNSELSPSLRTGKTGYVEDSISMRGLGNYFTLWLLLVGLVALFIFYPVVTEAGRSDLSDSIVNNPNINSTGQATAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQU8</accession>
    <name>A0ABQ8VQU8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Organic solute transporter Ostalpha-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_877760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4498773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="389" mass="44468" checksum="0D5B2757A0787EA9" modified="2025-10-08" version="1">MPTCPSDNQQAVDQTGFWNPDGGIDWDAHRIGWAIAGACSVATVLISMISVFQHCRTYTKPAEQRQILRILYMPPIYAVISFCSYRFFRSYTYYDLAEVVYEAFTLSAFLMLLIEFVADSGSGHNPESSIARKGKRSLPFPFCHWRYRPTKPYFMYTLKWAVLQYVILRPAISITGIICQAFNVLCESSGFNVHYANVYLEAIDFVTISIALYGLILFYALTREELAGRRPLAKFLAIKLIVMFTWYQSFVFDALEGRVIHATEYWSETNIADGLNALTICIEMIFFACFMWWAYTPAAYRIQGAKPTSIWRPLWDSINFSDFALEIWYSLKFFIAYIRGVPETHSRFAKSNAGFDDAFGLTTGRPVSYNKHSINIGSLRGQNGRTSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQZ6</accession>
    <name>A0ABQ8VQZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">mRNA-capping enzyme subunit alpha</fullName>
            <ecNumber evidence="3 16">2.7.7.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 16">GTP--RNA guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 16">mRNA guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_819935</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the eukaryotic GTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="3 16"/>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017075">
        <property type="entry name" value="mRNA_cap_enzyme_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03919">
        <property type="entry name" value="mRNA_cap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036959">
        <property type="entry name" value="mRNA_cap_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 16" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="5 16" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="18">
        <location>
            <begin position="132"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="376"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="381"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR036959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4497880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="431" mass="49725" checksum="C8EB306A80CD0058" modified="2025-10-08" version="1">MPIPDLPGELIPKHSPEESWLKSSVARVCQLENERFPGSQPVSFGTRDLLKLESQDFWVCEKSDGIRVLMFVLFDHNGQKVFLIDRHNTYRELTGLFFPHHENPLNPLRNTLVDGELVIDVDPRTRREITRFLVFDCLVVDNQNVMSRPLDKRYGRLNEWFYKPYAKMVRDHPHVAASHPFEIKVKEIRSAYNVEQVFSMDIPALQHENDGLIYTCVNTPYTPGTDSNVIKWKPPTENSIDFKLVLRFPPLPSSPTQPDFAAKPNFLLHVWCGDQNGTPRYEQYDEMYVDEDEWEKMKISGEQYDDRIVEVHWDAYVKGWRMMRFRNDKPNGNHKNVVENIITSIADGVEKQTLLSRSNRIRAAWKARQGALNQNATTLPARPPPPSGPPAAAPVNRPSHPIPRVELRYGPLQPSRWSKVAGPRNISGFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRM9</accession>
    <name>A0ABQ8VRM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Signal transducer</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_818597</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09395">
        <property type="entry name" value="LIM2_Rga"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051854">
        <property type="entry name" value="Rho-type_GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075">
        <property type="entry name" value="CHIMERIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075:SF2">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="84"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="8">
        <location>
            <begin position="1231"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="9">
        <location>
            <begin position="1304"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="763"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1277"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="929"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1009"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="379"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="601"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="786"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="825"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1277"/>
            <end position="1294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4498282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1505" mass="163880" checksum="D2F19C01257FA9AD" modified="2025-10-08" version="1">MIAALNPAVSQQQQYPMPDDLEERLCPGCKLSVVSEEGGLVVAFGQCFFHVNCFKCAKCNDKVTADTNLLLLSDGSPICANCSYACNVCKQPILDEAIMTGDDAYHAHCFKCKVCKNRIDELVFAKTSQGIYCMDCHNERMIKIRKHTQKKAERDRERQAAQTAAYNELGVGGANKGGSVSTSHRDRELRAREMLGKDTSSQTLQSSRSTEFSLNGHPSHPLRAPHANKASEYSRNNQSSVFHPPPRTSSVDSASQRPTPSKNHSMPVALEEPSLSNHPAVPSLSVPLPTNGGLHVTSTRDKRRSINPGLVIKPPGEPSTAASSLSPIQREPPSPVNDLFGGSPTSVKATSPFRENFPSSRPSSAASNNSAHVHRQRSRPTSVMSSSSVGATTSTIGDESTVTMRPSPSPLRPTTPRVSSSTRPNSANSLQKPERFSGRLSSRPGSAAGRDRPPSRADVPRSVESATDEDDDEEKQEIKGSRFDRALQRSMTDDSAKYSLIDAYSGVAADSTTYKDKEPHLRTFSVESVPPMPPPKDSKVGPPAPLSTLPKRVSSSSHGPISAMSDPPSLTPEPNALLSVPSPKSLNTPTGTAGLSVPVMSRNDSSHSNTSASTSGPGEVSDTETTETTAEDKELLDAEIEAEENGEESGNRATATFIAPALPPIRFSLNAADFSDLFTSVGGNMNSLKNLDTLATVAENHSSERTLWDITPSTPPPSAASVQPNTMSQTLNVQSVRVVPDLPGPEATSSSTLMPVHNEFSSSVYSSAHDPTSVVGTAEESVPNSEDGHSSNSDHHSKKEKGGLLRKVSFGKRNKLDRSASSSRALREREKRVTEAMPVPSNSKAGLAAPPLSRTISEPQVKNISDETLPSTTIMVSPPEDAKEEAKEPISAADLVLQRLQDVLADATDRGAQQMKFDRGFVEAIVNAMATKKADYVEARKQIDSMKRASKQYIDGISVAQTEYDRELKARRDAEAEVTRLRVLLSGQAARLTALTGDSRRQELRQQMSKELHENLNGLERDLSKLKVERDVTLAEVEELNAVSSISGVTSEPPANLSRSLTKRLDNLKSQYQRDLLPLTQQREALTREVMELKAARDVFLEETTVLNARNEELAQLSAQYSRRVAMVPPNGPSNSNGTETSSKNIGPMIVETPVRIDSRNIQQQQTPQQSHQLSAYSSVEEFDARKTKVEETHTPSRGPVKVFKWGSRAKEVSAPIAQSATEKVKIGHMEHSFQPLSLLRFTRCDHCGEKMWGSQLRCMGCSISVHTRCVNQVHSACSPQTHNPSGSGNNEDSQPLPPSMFGRDLIEQVLADAKGGSRKVPVIVEKCIEAVEKLAMDYEGIYRKTGGSGQSRIITQLFERGDYQAFDLLDSDRFNDICSVTSVLKTYLRSLPVPLLTHDLHDQFMSAVEIRDPVLKNSTLTELVNNLPPEHYHTVRMLMLHLNRICQLSEVNLMNARNLGVVFGPTLMRSRNPGAEFSDMAGKALSIEWLVETAPQVFNTPTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRQ3</accession>
    <name>A0ABQ8VRQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_915707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="37226" checksum="03A39E6BF5BC9075" modified="2025-10-08" version="1">MTQKYKYLSPEQVDHFLEHGFIVIQNGFTEEKAADWTKTIWIRLNLDPNDKSTWDRERIHMPWHRRERVATFAPKVWDAMQDLLGGAERINEEDSRWGDSFIVNFGNETLENATDHIHPRDLDNWHVDGDFFVHYLDSPEQALLVIPIFSNIKTGGGGTFIAPEGIRMIARYLACHPEGVMPTGLSFTPSTTICTDFKNDPGYWSHLKEVRNCSQFEEMVGQVGDVVLLHPLMLHSASKNYLRQPRIITNPPVSLKEPFNFAREDEEQYSLVEKKTLKSLGVDKLEFHITTERRRMTPKRLGVQEKLLEEEKQRLRDHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSL9</accession>
    <name>A0ABQ8VSL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_815430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4499370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="255" mass="27971" checksum="E10916D6C689B483" modified="2025-10-08" version="1">MADFLTSGNDDIDFDRAASAFPDISLDDIGDMPALPTTTSPAAPVPSSSGFSFDDFDSPTPAAAPVKVTGDDDIEKFESEFPDIDIPSSPPVMMHQTSQPSFGSAFAPIPQQSASLSTPTIVPEIPEEEPEVIKEWRRKQAEEISARDEASQRRRNDNIAKAEKAIDDFYENYAAKKERNIRENKDEEADYVQSLTESLSAGTTWERICNLIELQNSQSKTIARTGAGTTDITRFKEVLLRLKREGDMAPGAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTT2</accession>
    <name>A0ABQ8VTT2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FRG1-like family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_175345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FRG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23339">
        <property type="entry name" value="beta-trefoil_FSCN_fungal_FRG1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010414">
        <property type="entry name" value="FRG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928">
        <property type="entry name" value="FRG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928:SF0">
        <property type="entry name" value="FSHD REGION GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06229">
        <property type="entry name" value="FRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="284" mass="32100" checksum="A8C33B8A263ADFD9" modified="2025-10-08" version="1">MGDDKIRSTKLKFKGDKQKKKRRREDTEEGSSDNKRRKEDNVDPDTWVFPDNPNEIRGPTFIIHPSDPSPISLNFSSTTNRVVLHFIDKEKLEDDSEPQSLLERTPTDISQVWVTTRVAGSPTINIRSGSGEGKFLSANTLGIVSCDRDARGPQEEWTPVIMPDGMTALMNSYEKYLGIDEVAGGSLQLRADSDEVGFKERFWLKIQSKYKKEANEEEKTKKEGMAGPPKIDESATNHVYQAWGAGRSVVSSHDKKELKRARKEGRLAEALLDRRAKLKSDRFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTY6</accession>
    <name>A0ABQ8VTY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mediator complex subunit 16 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_820565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048339">
        <property type="entry name" value="Mediator_Med16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20719">
        <property type="entry name" value="Med16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator complex subunit 16 C-terminal" evidence="1">
        <location>
            <begin position="808"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="873" mass="97758" checksum="2D0764E67ADF317A" modified="2025-10-08" version="1">MEATWNSGWWDFHPLSEYPRKPVEWSNSSVIFTAHALQPLIIARHFSSSRQFNLPFPAPISSNLNTYDPPTIITCSPDDRWLFAFFPGRGEDGLCCLWHRGVELDSWSVKEWWLFAQSAGVVAARWLGGPREWTIDSSSGAPTRLPSRGPSTPVSNPTLILVTQDHRLFVCYLRYYKPKLNMFSCSLLQASVIVEQEPDNSQETLDEVDSVKICINAAIGTTYSDSSILVAMRSQVFPISFSVPTPDQFSLDLGLPLEMEPDQTEVYPTAREDSSEDSTIQIAEVQLQFDGTRMVLSSKVHPIIENAPNRLRDLCFVCKTPSNENLSSTSMHLVASFIDFKEYVSLPIFSMKCYSFIRTNASGGEKGTWTMQSEINRDFEPGALAQVAVFQPAYTDHGVYVSIYDTSGMQPRHKIQQAELSVGHLKMLKIPDLTYDDTWGASPVLAPIRTLGTEVPINSIVSPGQNLLCTIFPSPWSSQMSIQKLPRPSSSNLASSSGSIPFLALSIVTAILSNRSTDDLTHSLLPSSTPLIEVAEVLYHVFTLLDRYVPGAFTLQLGITVESYRSRTLRTSSNIHDRERADVIWRTAHDMISVATCNAVFNDCTDGQEYQTDLFWQMIDLSSWILGLVETIVKECILSSDFADSIESTGSAGDDLFGSDSPIKDTNLRSLDYPVFMHLVHIQALRNLRIALGHVNRFCKYLTGLTPRTENSHLSKEVLLDLVDYSGIDIPGLDKIFQELEDFVQEFDDDQMRKALASCSPSLSMQIPLREAVNSMSRSPALNKARLFIKSFEMIDGHNQTMSLDRSQKDKIKNRDVVSKGVLLYRAQGTECVRCGGRSEYGKDIMVSRPLNNWEKSWARRCICGGLWTRTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVB8</accession>
    <name>A0ABQ8VVB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Very-long-chain 3-oxoacyl-CoA reductase</fullName>
            <ecNumber evidence="12">1.1.1.330</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">3-ketoacyl-CoA reductase</fullName>
            <shortName evidence="12">3-ketoreductase</shortName>
            <shortName evidence="12">KAR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Microsomal beta-keto-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_751985</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="EC" id="1.1.1.330"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endoplasmic reticulum membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.330" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05356">
        <property type="entry name" value="17beta-HSD1_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03107">
        <property type="entry name" value="3_ketoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027533">
        <property type="entry name" value="3_ketoreductase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086:SF2">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086">
        <property type="entry name" value="VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000126">
        <property type="entry name" value="11-beta-HSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0521">NADP</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4500332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="343" mass="37372" checksum="581B693EB6FA7244" modified="2025-10-08" version="1">MSPRRFSVHETDSLYAANAYPLAASLLLGLGAITIAKFCYRTLSVFLQIFVLPGQSLKRYGAKKGAWAIVTGASDGIGKEFAFQLAKAGFNVFLVARNLELLDAAAAEIASKYSVSTQTASIDFAKADDAAYEILDRKFQGLDVGVLGKLNNVGKSHAMPAYLVDTPKEEMADIVSINVNATMRVTYSVLPGMIQRKRGLILNIGSFAGAIPSPMLATYSGTKAFLATFTSALAEEVRQHGITVEHINTYFVVSKLSKIRKSSALIPRPGPYVRSVLSKIGLPCGAAYSRRPNTSTPYWSHALIDYAMTVLDMPTLLIKYTHGLHKDIRRRALKKMEREAKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVL4</accession>
    <name>A0ABQ8VVL4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_751991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04515">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.200.10">
        <property type="entry name" value="MHCK/EF2 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004166">
        <property type="entry name" value="a-kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051852">
        <property type="entry name" value="Alpha-type_PK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992:SF2">
        <property type="entry name" value="EUKARYOTIC ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992">
        <property type="entry name" value="EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02816">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00811">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51158">
        <property type="entry name" value="ALPHA_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-type protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="241" mass="26894" checksum="B45887BF1D76C1CF" modified="2025-10-08" version="1">MEECTIDVPRNWRRFAKGGVPKGGYRGKGSFKYCIEARYNAKPVALLQCIPELGSTTESNRNLLLKEFEILIQASGFAESFNERAKLAGVSIPGSGLTFNITDAFVGTTILPIPSGGLPMEESIENDDRSLLYNTFLVVPLLTISGLYQEKKFSGNSMIGYNDDDFAGKLIDAFAHHVLEHTKGEYMLADLQGKDTKILYSKYQDSGDWDRGIEEIQKFCQKHHCNDICTQIQLCDLSKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW46</accession>
    <name>A0ABQ8VW46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">TKL/LISK/LISK-DD1 protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_751600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050940">
        <property type="entry name" value="Actin_reg-Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46485:SF5">
        <property type="entry name" value="CENTER DIVIDER, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46485">
        <property type="entry name" value="LIM DOMAIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="15"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="12">
        <location>
            <begin position="520"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4500603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="600" mass="65390" checksum="0D4AB48B9B4481C5" modified="2025-10-08" version="1">MHSDAFDVIPYEDIKGDWKTLGSGSFGKVYKGTYLGIDVAIKEVLPSTEYDVAKYFEREWRLMKESRHPNIVLFLGLSRAPEPDNRIFIVSEFIDNGNLRHYIHDKNKPFPWRLRLSFATDIARALAYLHARKCIHRDLKGENLLVTANGRLKITDFGFARIAARSEDESKRLTFCGTDSYMSPEILLGEEFDLPTDIFSFGIILCEIAARRLADDHHFKRAAPTFCIDADEIRSLANPGCPPDLISLCIECCSPNPAARPTTRQILEKLRVIEAEVLSRPNEGEDVNVGSIKFMTGHKRPGPQPRIPSFGMGVGKDIRNSGSSTDDSDDEDELMEAVQGLSGVGLNSDWTEAPNGKEPLLNGNASAISEYSTTVVRAHPNHDGNGTQAPSLSSILTIRASPDPNAINNQVLPGSDHSPEASTIMAEHPANGSDLLGHSSILSIDSLDSYHTAAGSSIISSTMATEGGSTIKSLHGNYSAPLVHRFTILKPGAKPTKKSGNSTPPTNAPVAEPLSWNPFDLFFSGGSLVSKCDVCSKRFGPWKPILECDDCGLKAHVKCGDDAPIDCGVRPVRPRVHHQPSNSLGKLKFGKGEKTASPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW86</accession>
    <name>A0ABQ8VW86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_810456</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09326">
        <property type="entry name" value="LIM_CRP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09401">
        <property type="entry name" value="LIM_TLP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF35">
        <property type="entry name" value="MUSCLE LIM PROTEIN MLP84B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="8"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="246"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="79"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4500647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="34470" checksum="7011619DFBD7BD3A" modified="2025-10-08" version="1">MHPFGGTPKCPRCQKAVYLAEQVIGPGRKLYHKPCLACTTCNKRLDSLSLLEHNEEPYCKSCHIKNFGTRDLRQANHPYRARSPSLSPGKTSNGQPQRSFFPPPSPTHPRPFATGNGYIPQSPAHKSISTATSSLPHNDETEFVGISTNLDEECEEGRDSVESLTRKTVESPFKPSHHNPSGLSQIVGDDNTAAVAAIDKFRNTVGRSGAMRPITQTPTGTRYGVALGGPVAHTTGSPRKWGGETPNCPKCGKSVYFAEQVKAVGKTYHKGCLRCSECSTSLDSNKLRDHEGVPLCSRCYNKLHGPQGNGYALLGKAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWG2</accession>
    <name>A0ABQ8VWG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_907655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="5"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4500664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="29417" checksum="7FD3A64C66AE5FAB" modified="2025-10-08" version="1">MTLDLILSFDSLSRVDGSARFGFGLYPQYLTSISGPIEVRLASEQPSQSTIEVHVRPLTNVPGTESKKAAVILKEVLQMEVIMEANPRTLIQFVVQALVPTPNVTDELVAAMINCCTLSLLNAGSVPMRGVICAVSIVRLSPVKGEIPIYKVHLTEEPIPRLEATGCFAFLFSDSVSSNTYASSCIWTNWHSSYSGSAKAVDEDDLVRARDVARSAAREVWDRMKLLIEERERPKIAMRGSLVKNASHEMADAEKMDVEEDDAKMEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWQ8</accession>
    <name>A0ABQ8VWQ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_352727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046222067" evidence="1">
        <location>
            <begin position="24"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="398" mass="38784" checksum="57F1D238769C1C07" modified="2025-10-08" version="1">MFTATQIGALTLSILAASEDVLARPLLAFRQSTNSSIGDFGSCTVPQIQFATGFDNRKETSFEPVDLTSYPHGSAQGIDIITQFMCDQLVNSCGADATAKATCASAAAAADTATAKTGAQADKFNAVFGIQTNFAAVPVVSDQGVTLGVDGSGTSAAAATSAVAVASAASATTTSVAATVADTATSSDPCPATVTVTVTAADAASTSAAATDAATDATSATDVASTSAAATDAATDTTSAADVATTSVAVASATAEASSSAAVATSTASAADIGNFGSCTVPQIQFGVGFDNRRETAFEPVDQTSYNHGSADNIAVITDFMCNTLTNTCGADATAKATCATAQAAAAAGLAQTGDQADKFNAVFGIITTFAQVPVVSNTGTTLGVDGTNTAAAATATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWS6</accession>
    <name>A0ABQ8VWS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyltransferase ChoActase/COT/CPT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_814806</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF29">
        <property type="entry name" value="MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="5">
        <location>
            <begin position="49"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="743" mass="83302" checksum="A7AF1D6CB67D6E9D" modified="2025-10-08" version="1">MSESPDDNRCSAFLIYTPATVCFYPMFSNNDADIVPGQTFASQDKLPKLPVPPLEETCRRYLRALEGLQDPEEHTKTKEVVREFLENEGPEIQKKLMDWARTRDSYIEEFWYESYLSHSDPVVLALNPFFVLENDPTPNRGSQLPRAASLIIASLGFIHDLRAKILEPDHVRSTPLDMDQYTRLFGAARIPTDKGCRMEVSTNSHHIVVLRRGQFYWFDVLDSENRPLLTEREMIRHLQAIVDDASTLSTKDVAQRSMGVLSTENRKIWSKLRATISSDRHNASCLEIVDRALFIVCLDDGLPMKDDLPQLCSNFLCGTYGLEEGIQVGTCTNRWYDKLQIIVCSDGAAGINFEHTGVDGHTVLRFAADIFTECLMLLARSINPAAPTLFHAQLSPHAKSYKQPRNAKTTAPDVGPIDTTPKKLEWDLTSELRVGIRFAETRISDLICQNDCQALEFKGYGKNFITSHGFSPDAFVQMALQAAYFGLYGRIECVYEPAMTKAFLHGRTEAIRSVQSESIEFTKIFYSEAPASAKVAALRKACERHVKLTKECSQGLGQDRHLYALYCLLQRERQAGGENPLPAIFSDPGWVVLNTSILSTSNCGNPALRLFGFGPVAAAGFGIGYIIKDDGLSICASSKHLQTRRFLDTLQGFLLDIQRTVIHLHRAANERPSPFVDHSGVLRDARTGRPINGRVLDDEEEDEIALPGYSFFGSGDVEKILGQRKRAEQPYSHIGKVIQMAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXW7</accession>
    <name>A0ABQ8VXW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_862430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046521">
        <property type="entry name" value="DUF6698"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20414">
        <property type="entry name" value="DUF6698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="51102" checksum="7F99CB08F6D5F1D9" modified="2025-10-08" version="1">MTIMIHEAHRHPVESVLFNNPSHILHATIASLRTRNASETWNVNLLVQGIQRKRKAESERRHIHTLLAQYDEYRHKGYHQLDSEGDDDDIDIEEKRRLQRGYSGIMTLYKTVYPDFLKKIKEPGSAHIIRELQTGANSSRAFDTSTVMKFVGDILNEEVRKINQAKLKEYQVKLRAYTENVTTGDSASDFPTATTNTMAEPVLERVEEFCTTSRDNRGLQNDVTGYLLCPAEFDWNDTAVRAAVRAFDPNYDFASSAHARCFYKDEEFDPDDFDKGFLQSYLLVQVYRLMFTSPSSTKDQPQDVENLPASKKKKTTGTNHRGNVAQIIHMNDVKPRSIAYAAVHLHFALSDASQWTNSHMGYNYLDLWNFIVDFFEDPEGEEEEQRSKELLKWWNDRIFTGTRAAANSCGTKMTSRKQDVSKRLRVASPLHDIFSNGTGAAPGPASST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXW8</accession>
    <name>A0ABQ8VXW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="611" mass="66918" checksum="23F6A12F599AE196" modified="2025-10-08" version="1">MSLRRQNRVSTLAIVLPHPPLLRRRSSLLSQGSINSPHTPRTSNCASPTCQSWLFANNNNRKSTDSWNSSNQDVGEDCESEWKPDQILLLSRTLDALPSHLVTPFNGPIPPSNLLDKIARGVANAKGPAEWPHSLRATRVKLIEIARQRAKEDPPRGPKSVVTDENDDISCYSTDSDLNAGLSRKRSRVIPRRPLYRQSSMDFVNPGDRKNGDNITRLSTRLQRTDSLVPNPNYHPYTRSRARAQTQSQTQARIDQMNRRSSSPPRPAHVPSLISPSTPSSSTLNSFSSLSTSAARRHVIRRSASTFSSSDSSMISGNRSSLADSEVKPHLLPSVLPDPIDARVQRVRRSESFYNPPYSASNDNHPFVASARTPPSTHQAFKRAPSYGALVQEAREREKEKRSNGAVPHIYGSKSREEMNVSPCPSSDEEEKLRNNQAKKVKGPGGKASRSPAAPLPPDSRSSDQGKAKKHTKAKDAVCSESKATSYRLKSPPPPASISAVVPTQPLDHPRPQMNLQHSSIFGEELPHLHIPAAPSRPIPSASSSSSNQRPTATPSQPAGPPRKTLRRVKRLAPSRKISFGSLIAPNGNDTDIEDDKGGQHPKLGSAFQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY90</accession>
    <name>A0ABQ8VY90_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_863507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="26403" checksum="CD648F0D6E51D0AB" modified="2025-10-08" version="1">MALEPSLPFPILILSSPFVSLPTHHMAVRTLQDLVEDSPPTESEVYNVFEEAAPFLIYIHDFWMGRANCLLFTEQVLLSAELLSLSLPAFLRDDLTQQWGIPPEHRSSAESVHKFERFPAIPIPFCLRFCEESVMMRSVSSTDLDVFASLRGKGSLAGASKLNVPAPPLEIMSSTSVAKALVAPPRLIRRNRELESLKAEASTFFSSPCSTRSRDSDNELLSGFPSAGRNLKLQLLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYQ8</accession>
    <name>A0ABQ8VYQ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aquaporin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_914212</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF14">
        <property type="entry name" value="AQUAPORIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="329" mass="35307" checksum="53F7A07D6904E1E3" modified="2025-10-08" version="1">MSTNVVHLRDVQARSKFFTVWERHRHTTVHWLVECFAEFLGVFFYVYAGPQGVGSQVPFIVGPILSIDGLSSVLQIGLAYACGIIFAISICGATSGGHFNPAVTLTLVLFKGFPPFKAVRYIIAQILGGYIACLLIYVQWHDLIKESELVLAAAGTLDATLFTPQGPAGAFGLYVIPGLNLGGVFLNEFVTDIFLALVIWGSIDPTNVLIPPQLAPFVIALAYAAAIWGFATPALAANPARDLGGRLAAMTIWGTKAAGGRYAAIAALTSIPATMLGVFIHELFLTDYARVIPSSQREYMEVHHNHLHAPGKAASDVSSNEKADLEHNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYW3</accession>
    <name>A0ABQ8VYW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_892182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024729">
        <property type="entry name" value="USP7_ICP0-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029346">
        <property type="entry name" value="USP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14533">
        <property type="entry name" value="USP7_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12436">
        <property type="entry name" value="USP7_ICP0_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="43"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="201"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4501526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1100" mass="126578" checksum="9441F3204CDBDDE0" modified="2025-10-08" version="1">MDTLDEKANGGPSMEIDEIVSVRNHEAFAAKHMPDLGQDIKDFQVFTWRLENWKKLDKKLTSQEFECGGHKWRILLFPFGNSNAPPNDTVSVYLDYAEPKKAPEGWHACAQFALVISNIHDPTVFTVSHAHHRFIAEECDWGFTRFSELRKLFNVQEGQPRPTIENESADISVFVRVLEDPTGVLWHNFVNYDSKKETGFVGLKNQGATCYMNSLLQSLFCTRYFRKAVYQIPTEDDLPTESVSLALQRVFYHLQTSDQPVGTTELTKSFGWKSLDSFLQHDVQEFNRVLQDKLESKMKGTIAEGAIAKLFVGKMKSYIKCVNVEYESSRTEEFNDIQLNVKGMRNLYESFKDYVAVENMDGENKYQAEGFGLQDAKKGIIFESFPPVLHLQLKRFEYDIQRDAMVKINDRHEFPFEIDLGEFLDANADRSKPWKYRLTGVLVHSGDLHGGHYFALIKPDRDTRWLKFDDDRVTPVTDKEVLEENYGGEPLNGLPPTAQRNQVRAMKRFTNAYMLVYIRESAMDEVLAPFTEEDTPPHLKRRLDEERLQSEAKKREREEQHLFLTAKVITDETFSRHEGFDLATFDEKNWPPSDLPSFRVLKQETYSVFKSRVAQHFNYPENQIRLWVLVNRQNKTVRPDTAIPENEPTLTVEVIRNNMAARQNDLRLYLDVVTDPSKPESPPQSIMVFLKHFDTSKQNLLGAGKVYMPRTSKVGDLVPIINERMRWTPGTPVKLYEEIKPGMIELMKPKLSFAQSEIQDGDVICFQVDLPEKEIHDLESQGLHSNPIHFYDFIQNRVMIIFRPKYEDSDHDHPEFSLILSKKQNYDTMSIKAGEYLRHDPIKLRFTTTHANNGNAKSVLKRSLNQSIAEIMAPYYTTSAVILYEKLDVSIVELETKRSLKVIWTGIHNKEEGTFPFLLPKTSSVYELAENLAKQVTLTPSGTGKIRIFEISRDGKTQKEFTGSEMIGNIPDPVDLYAEEIPREELEADDADKVIGVFHFSRELTRTHGIPFKFVVKRGEKFSDTKKRLQARLGVSDKDIAKYRFALIQGSTFKQPSYIEDDDTIYEHQFAPEDVLGLDHIDKSGRSKAGVAEKAIVIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W041</accession>
    <name>A0ABQ8W041_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_749352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045469">
        <property type="entry name" value="Nis1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19271">
        <property type="entry name" value="Nis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="18767" checksum="DA95E2F62FCC1071" modified="2025-10-08" version="1">MKNILRSISYSIALGAFVSTRVALGNPVIWIPTEGTTLTAGSEVTVMVQDSSYATPIQETSLSIGLSPCTETSCPGPDTSVLYLLYTGAFDPQRPSSPVNYDPGSYAFQNFTVTVPAEAESGSYTLGVLHSYWGESVRFIVSSRFAEELIFVLCSCLLNCRLSRCTSPRLTSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0K8</accession>
    <name>A0ABQ8W0K8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_808335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="167"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="322" mass="35494" checksum="E002EAA599ABB89D" modified="2025-10-08" version="1">MAQAATLDNTMGAMFIGVLFAAVLYGAACIQTWYYYIHQKDRWPLRFLVAAVMIVDTLHQALIAHTVYTYLISNFGNTSELLNTVWSLLAEVLVNGFTAVFVQSFLAHRVWQLSNGNIWISVPAFLLVAAEFVSVFVFGVIGLTRVHTFVELSDILKGLSITVNVLAAVADTYIAGLLTLLLHTSRTGFQRSDSIINKLIIFSINTGALTSLCAIASMLSILLAPATFIYISFFFCMGRLYANSLLATLNIRTLIRKEGGSNVQASGDTGSIPLGNYNTSIFNPPSTISVKIDTSREFTTDREREQKRTTDFEDLSSRMNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0Y9</accession>
    <name>A0ABQ8W0Y9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="11"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="363" mass="39855" checksum="D799510B392EDE8F" modified="2025-10-08" version="1">MSPAARATTTNLFSPIKVGNMLLNHRVVMAPMTRLRTTKTSALLKVVKEYYSQRASSPGTFLISEGTVISPRATGFPGLPGIWSDEQIAAWKEVVEAVHAKGSYIYLQIAAMGRAAQPSVLQSYDPTYDVVGAGDIPMTGGEVPRPITVEEIQASIGDFVQAATNAVHKAGFDGVELHGANGFLIDQFIQDVSNNRTDKYGGSIENRVRFALEVVDAVAKAVGEDKTAIRLSPWSKEQDMGMENPIPTFTHLISQLKEKQPNLAYLHLIQSRDLDDPKQSNENFFDLWSPRPLVVADGINREKALKFAEREGLLVAFGRQFISNPDLPLRLKADIPLSEYDRSSFYGGDESGKGYIDYAFASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1B3</accession>
    <name>A0ABQ8W1B3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047245287" evidence="2">
        <location>
            <begin position="23"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="340" mass="37415" checksum="394069D5F5719743" modified="2025-10-08" version="1">MALFRLSNLVALLTFSSLTVLAFHFIAGHGDASGFFDKLSAPCLNITPDEAPFSLPYTGIQSVDKTLCGIIVFFHASFGPEIAPFLIYFLLSAVPITGHAYFESSRLKRPFLMAYPVVFFQVMQLLSFGATFSVYWMLFILSGASRLPSLGRQTMVTKAHAQAIMFGIFIGLVILTGCMIILQDPYITAIWQVFPIVLSAATSLHLLVRPASLYPESGFSVIRGFYILSFILISSMHITLITSRGIEELKALMLPSITVLPSSTSIELQALNLLQWDAAFGLLSALLATLWFGRNTKETFVLLAWNLLASLLVGPGAAFAASALWRESWLHEELISDKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1G3</accession>
    <name>A0ABQ8W1G3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pre-mRNA-processing protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_913163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="5">
        <location>
            <begin position="182"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="206"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="356"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="592" mass="65653" checksum="33A41ACC9FC8F6F1" modified="2025-10-08" version="1">MSALAAALPKPLHTSVEDEEDDYTQYARPAPSTSQQVIARFIVPPYGQRKGWKPSKVEDYGDGGAFPECHIAQYPLEMGRKKASSGNTLALQVDSEGNVRYDAIAHQGQRPDKIIQSQFKDLVPLAQRKDLDDSDRQMERPPDEEVQATADKTRAALEKLVNGKIKAAQPKNVPGSLAKTSFIRYTPGQQNGDGLKQRIIKMSEIVEDPLEPPRFKHKKIPRGPPSPPPPVLRSPPRKATAAEQKEWMIPPCISNWKNNKGFTIPLDKRLAADGRGLQDVHINDNFAKFSEALFVADRHAREEVRQRSLMQQKLAQKEKASKEETLRMLAQRAREERNGSVPKPTAASQAALKSSLAAYGSDSDSDGESGSESVDSAEDEEAKKIRDEMRRDKRREREREMRMSNMGQEQRAKQLARQQNRDISEKVALGLAKPTMSKESMLDSRLFNQESLSGNFGNDESYNLYDKPLFHGSTAAAAIYKARGNIEQGNEESFGGGTDEGIGKALDNDRFSLGRPQVGFEGASDQEVREGPVQFEKDTSDVFGVNQFLSEASTGKKRGLDSAGQVFHRPKLCHSNSLVFSPVEVVHGNDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1P7</accession>
    <name>A0ABQ8W1P7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_913561</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="21"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4501025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="614" mass="67725" checksum="49B7D2E97AE44829" modified="2025-10-08" version="1">MASNLAIAEKTTPLITQLHGIIIGGSISGLSAAIALRRAGHRVTVLEKDPMINEKLGRGFRIAPNLHKILCEWGLEAELKEISSKPKMMNMLSYNNGTYLGSLTWDQEVLKETSGEFRLTTYSALWTLLYRETISQGACVRFRARIVSLKTRSISPSVTLESGETVYADLLIGADGVNGLTRRYISASASPPYNYGHNDRKDQRAYGDAKPGARIESAKFKMFRYLVFLTCISHPIPSSRSASIPKKLIINDPQLAYLINRRENDMFVWIGHEHSAIGFPSGNSSDFFLNVYGLESGVQVQDLQHVLYGAESSLLKLSRIASETFSSLTYATLIHESVLETWVDGSLVVIGEAAHPLPPGSVQSCALSVEDGAVLARLFAPQSLSWRSKSCGLVSHIPTILAAFQSIRYQRCASVQTREVGIIHYMTMPGSSEAERNVRDQGMRARRDLVELAVVPVPPEIADFFKTDFDDDVEEEEEGLCYQVTNANLTANTGDRLEISPEWVEASEVFGYQAEEEAEEWWATWGRYQIQTEVSPAVAIGGNDETVCNFFQKLSTSDPLHSNSSIAPHSPYTLPSSSNSEENWNHTPACTSAEFLTHKLIGSSEDGCGCCFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W1R7</accession>
    <name>A0ABQ8W1R7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_14590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045750505" evidence="1">
        <location>
            <begin position="23"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="102" mass="11526" checksum="218C4186F4CDA453" modified="2025-10-08" version="1">MLGCAQNSYLIFFFSLLLLSVAAPLKPVDVDIRNLNSRVLYSQGPKKVFWHAKKPQKVKNAIHMFFKIVLPGLDKSESVSSIRIKPSDWEGVPDPRRSTISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AY46</accession>
    <name>A0A9W9AY46_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8J55DRAFT_533948</name>
        <name evidence="8" type="ORF">C8R41DRAFT_781061</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000120">
        <property type="protein sequence ID" value="KAJ4465879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000005">
        <property type="protein sequence ID" value="KAJ4491984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AY46"/>
    <dbReference type="OrthoDB" id="275748at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000286">
        <property type="entry name" value="Putative pre-mRNA branch site protein p14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4465879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4491984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="122" mass="13780" checksum="72E265EB13B7423B" modified="2023-11-08" version="1">MALARPTSKLPAGANRILFVKNLNYQITGEDLYDLFARYGSIRQIRMGNESKSKGTAYVVFDDVMDAKNALDHLNGFHLQERYIVVLYHMPAKQDAAAAKADLARREEELAQLKKKHNIGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B1F9</accession>
    <name>A0A9W9B1F9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_532772</name>
        <name evidence="7" type="ORF">C8R41DRAFT_762627</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000002">
        <property type="protein sequence ID" value="KAJ4494538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9B1F9"/>
    <dbReference type="OrthoDB" id="268479at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000027">
        <property type="entry name" value="Proteasome subunit beta type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4494538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4495344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="258" mass="28913" checksum="15C786AD1C5AEE32" modified="2023-11-08" version="1">MPDMVTLPYSSPGTPQQRQFNPYSENGGTILAISGADFSVIAGDTRQSEGYSIQTRYAPKVFRLTDNAVLAVNGFAADGNMFVKQVRQRLEWYRHAHAKDMPLRAIARLIQTMLYSRRFFPYYVYNILGGIEEDGSGAVYSFDPVGSYERESCRAAGAAQSLVQPFLDNQIYFKNQVPQPGHPHPQHLPLTTVIQLVIDSFTSATERHIEVGDGLEMFIVLAKGSPLYGLENIDGVQEMTVTNEGERIFVVRRNLKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW99</accession>
    <name>A0ABQ8UW99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_872343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000154">
        <property type="protein sequence ID" value="KAJ4463705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047402345" evidence="1">
        <location>
            <begin position="29"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="164" mass="18020" checksum="B69AF2273B9481B0" modified="2025-10-08" version="1">MHFPLPGAGFKVFIVFILGLVSFACISARPLTNSESNLISRSELNSAPSKILPSKIACNIKNDIRKAISTNIVSGHTVKVKFSQLVPEFNKNQEIPFLITWDNGAQSGPSKGVVKKILEESDQFHVEVELNPPYSTPAINASDHETVESRSYFSQAQTCDAAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWI8</accession>
    <name>A0ABQ8UWI8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_783271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000150">
        <property type="protein sequence ID" value="KAJ4463934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="19761" checksum="FFB5AB5DD2A9A64F" modified="2025-10-08" version="1" fragment="single">MAWYSSRSPYARILNTNFLPSHAQRKEIETFLSEPQQELSRLETEILRVRVILDDLSSQRAEVREYVKIHRGLLAPIRRLPVELLTEIFVLCLSTERYPVRSLREAPLLLTMICRHWREVTLKSPSLWNSLHIFLPQDLTKEAVTLRERGVNQWLTRSGSLPLSLSLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYV8</accession>
    <name>A0ABQ8UYV8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_906857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000158">
        <property type="protein sequence ID" value="KAJ4463604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="3">
        <location>
            <begin position="61"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4463604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="233" mass="25980" checksum="098CE3F9B8DAF2A5" modified="2025-10-08" version="1" fragment="single">MQNQTSLTNPDAHRGPTATNRHLFGLNPKGYFVNFDFDGDYEQRFPSDAMYEELGPNARVWKTYLAETSSLDENMVGEARDGLVSMLVFAGLFSAVVSTLLVQATQNLQVNYTEVTASLMFELVQIQRAVAVGTSVTAVPTSLLNPTTKVKPDNLNVWTNGLWGISLSLSLSVALATVLVKQWLHRYLAVHSGTPRDRSHTRQFRYTGFEKWQVLNIIGVLPVIMHISLAFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ44</accession>
    <name>A0ABQ8UZ44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_856777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000114">
        <property type="protein sequence ID" value="KAJ4466596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4466596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="150" mass="16728" checksum="E4789CC91D2C61AF" modified="2025-10-08" version="1">MQLEITLSRFFVHLLNWIVKHVCFSGILILGSFFNTLRKKDFLLLVLEFTCSAVFMGCFMFLLSRARTATSRRRTIHLDDLESGFHIGTIEAISVMSACPICLADEMPLLNSLALGSSVTGSDSEREQTPSSKFLPSDRYVIGGGRWGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZS1</accession>
    <name>A0ABQ8UZS1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_779777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF34">
        <property type="entry name" value="NAD-DEPENDENT MALIC ENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="7">
        <location>
            <begin position="76"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="6">
        <location>
            <begin position="264"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4467332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="563" mass="62363" checksum="F8EC0EE451B37E7C" modified="2025-10-08" version="1">MSLPKFQVALRGEALLAHPRFNKGTAFTASERKAFGLTGKLPYRINSLDEQCQRAYDQLQSQSTDIGKNSFLQSMKDQNWVLFYSLLTRHLRELIPIIYTPTEAEAIANYSHLFRRSEGLYLTFANRDSMEEDFLEATKGKSIDLFVSSDAEAILGIGDQGVGISAAKSVIYSLIGGIDPSKAIAVTLDVGTNNESLLNDPLYVGWPHERIRGKEYDDFVDKFVQLVRKYFPHSLLHFEDYGVTNAQRLLQRYRDTHAVFNDDIQGTGAVTLSTLMAAIGVTKSKLCDQRIIIYGAGSAGLGITKQLRDAMVSINNISVEEANAQFWLIDKHGLIRESLPDVREDLKEYVRKDAEWEECQSNGDIKLLDVVKKVKPTVMIGTSTHAGGFTQEVVEAMAAGCDRPIIFPLSNPSRLVEVDPRDANDWTKGKALLATGSPFPPAKMPNGKDYIIAECNNALIYPGLGFGSMISQSRIMTDTMIIAGARRLASLSPALKDPDDALLPDFGDAPSVNFEVAVAVAEQAIEEGSAGVDWKKEEVREKAKERLWQPIYGEYVYDKNGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V078</accession>
    <name>A0ABQ8V078_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_855126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="54574" checksum="800B30882A7AFF61" modified="2025-10-08" version="1">MLNVDVITLICEELEFGTSRCLDRTFRTTEDLNCRKGLLSLGLSSKTFLEPALDVLWRTLNRVEPLLSVLPETVSLNGKKMIMKQIALPSWDRLHYYASRVRIFKDDGTDNVHESVYAILGQSKPIFPKLAQLLPGTQICTYSLVFFLTSSISRAVIPSPYFPQSEHLDFGPSLALLASKSPGLRSLFITTTQFSGISASLRGFRELEDLHLGRLPQYEKDYIQSLASLTKLTYLNLTLLSDDSFDYVGLQNSFPSLKQLSIIGSSSELHNFLKIVTPLSLQILSLTWHGDPSIIDAIDVTTSLGRFSSLQNLNIDNATSLFVVDPDRERLWSLFNPLLKLTQIRSLRYSSPLFLTDQITATIASSWPHAETLHFTAVSWSEIPPVSSLAHFARECPNLDYLQYPIQIDVSPGAADPIPPTPFMHPLRDFICSVHYDVLDPLYVALSLHQIFPSLKNVSGDGDKWDEVKAILESYHLILAQDRRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Q4</accession>
    <name>A0ABQ8V2Q4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_604754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000089">
        <property type="protein sequence ID" value="KAJ4471012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="69"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="368" mass="41515" checksum="A243DC341F73AFC8" modified="2025-10-08" version="1">MPAPLQIAPFIFDAPHVRHLENIASSSSSFSVNIVQKGIPVEPCSPGLKMTAKRYTSGFSGDNTFGLTLLFAHGVGSHKEQWEPTIERIFLTQATKERHHQIREAWSFDWQNHGDAALLNEEALKGRHEGVSIYEWAPAIIEFVLSPRMVGHRIVPLGHSAGAGAMMLTTKSFPLSHLPYVSLILIEPTMITREMFEAHFDDRIRSMEMSVGATEVRRDVWPDREEAFRWLSRRFPFRTWDPRVVRLLVEQGLYQKSPGSKAVSLKCDRKQEAISYPDVDGHFEATTELARVCRALPVHVIWGTSNDMFPDYFQDSLTDATQGRIVASASKVHGAGHLVMQEKPDHLALKICEALDTISPYLSFRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V433</accession>
    <name>A0ABQ8V433_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_584146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="140" mass="15822" checksum="50A1BCF206AF8091" modified="2025-10-08" version="1">MRAGTGEMLFEEIVLQKLEIVLSELPIDIPSNHWLSDPIHQVFPHATEVALNTAYLFLTLAGWTPALLFALSSVVLTLGQTISLCIQAHFYPNFLPKAIHLSTVSWSLVLIFRVLIPSLVMFVICRELCGRLMEVRQHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4S8</accession>
    <name>A0ABQ8V4S8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mitochondrial glycoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_559394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.280.10">
        <property type="entry name" value="Mitochondrial glycoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003428">
        <property type="entry name" value="MAM33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036561">
        <property type="entry name" value="MAM33_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10826">
        <property type="entry name" value="COMPLEMENT COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10826:SF1">
        <property type="entry name" value="COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02330">
        <property type="entry name" value="MAM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54529">
        <property type="entry name" value="Mitochondrial glycoprotein MAM33-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4474206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="268" mass="30178" checksum="15D78E16ABA12D72" modified="2025-10-08" version="1">MSSIRALRQLSTVSSRSAVFRSTSFVARARLASLQVPSRTFSVSARSFGQGTADVALSNKLTEEMKYEKESMTDSPKEAGDILEQFKAQGKWQIEDTSFNDEVTLTRKFGNENLRLTFSIVDIRGEQEDFDNEAASEENDEDGSQEEEVLNTYPIRVSLTVTKSSTPGSLAIDMMCQEGQFVVDNIAYYKDGSLATDLTAEADWKRRGIYMGPQFDTLDIGLQEEFDKFLQERGVDQTLALFIPEYAEHKEQREYVSWLEGVKGFVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4U7</accession>
    <name>A0ABQ8V4U7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_561012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19704" checksum="E952349940AF5BA7" modified="2025-10-08" version="1">MGVIEADYRYYRCPTVELGGRLAAALCLFLHTLFAIAAVVVTMTTSFELATPNVMLTVIGVLGLTISYRAASATPHAITRLIRYQVPPCRTLRTFGERAIAEWKRLGQELPEVMAEKKMALDLGEGFSVALKHHFRGEPGLYYEDLYDLVCPLQPQSLSPNYPDLLVSKTPPRHLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5C8</accession>
    <name>A0ABQ8V5C8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein BNI4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_549813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751:SF18">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR PHACTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="988" mass="105840" checksum="DD0C0F57BCBB67BF" modified="2025-10-08" version="1">MAVLAPSDWQYLPRDSHAMDLPSNNSRQQRSSPANDGTSPSPTTAPPHGSHPQFQQMNHQQSQQPPQQPYPYPVQQQPQGSWTPSISAQPFYPSFYQNHQQSPQGYPQLPQQAPYFDPANAQLAQWAYQQMMFNAQQGFIPPQQTRSSSGRSGSGPSPDYFAQNQMNPMFNPFPSGTPPPPHPNRTASVDQQQQQQQQNGQYPGFHPYRRPVRQGSSQSHPHAADGEWRPANMPIPPYARPDASGSSSSVNSTNSQRQRTNSNQSGNSGQNTPPGGSIRSRNGSPAAAGNQQPVSTATAARSSPSGSTSSTSSATPAAPKLPHNRNLSSSSAGSYTASSRPSGLAPSITSPPMSTTSSTPPSSASSTNLRPARPSPLSQGTFTASEKRMSRDDSDLAAMLESTPSAAMIRSGGLKGRLRRALTFNAQQQALKEEEDDDDASIKASALGSSSSKLKPKSAHSINTVVGQSNPGGGVPSPDIDDAESTATVQTKKKSRAASLFNSRLNASTDNISLSSTVSSASVMIRKLGSMGKLARRNSLAGITSLFKDKEKKNKEKEKEEGESADKKGKKKKSAKAEASEASVSHVTAELDRSAGDWGGPEMNGLSPAAKLARQHTLKSNAEAAAKAKAQQEATVAAAAAAAVSSTQPNGYGSGAGVPTWEKNTHTRQGSVSPVKGGGGFRINEDGTRVLVEDDDEDRSDDGHYGVPTQSPGEYNPEGWDDDEDWDGEDDEDVTIRMGIGRVSLDNEYEEPDPWATDIRRSVERTRVPAKGILKHAATYDQKSYMTENVTANRLRSNSYNSHTHQAELGPLARIPSPDPDHIDGLHRHGSHSSGHGSNSTITAAPTIPPLSFEPSAPSPIRATNFDSPRDSIDSTSTVSHVPHPPEKSSLLFSHSNSSAPALSTISSKAPTLTHRSATTPSKRLAFANNLSVYDTFPSSVYDRRSEPATWSRLTPALAQRIKEELNSYKMEEMEVHAASRIHTQFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5P5</accession>
    <name>A0ABQ8V5P5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Permease for cytosine/purines, uracil, thiamine, allantoin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_776364</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000084">
        <property type="protein sequence ID" value="KAJ4472412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4472412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="516" mass="55483" checksum="30CECD9B5DBF2945" modified="2025-10-08" version="1">MSAEDSEKAYSSSAGDDVPEYAGERAVNKKAAERFGVFAPVMEKLFDYGVEARGVERVLENERDPKLLWNNLFMWWSVNCVLTTVPIGALAQAFFTLSFGNACATILCFGALGAAFTSGIATLGPKTGLRTMIIARFSSGYIGGIIYSIFNILTQLGFATTCVILGGQTLAAVRPDTLSLEGGVAIVAVLSVIPCFVGYELLHRYERYVWAPILLVMLFLWGLGGKAGYHVTAQKAFEDPAGRFLAGDVLSFGGIVFGSFTGWAPVAADYNCKLPVNTSAWAVFFMTFFGLYLPVCFISILGAALMTITNPVYVAAYEDGSMGGLIAQVLTPWGGFGKFLLVVLALSVIANNMVNTYSTGISIQALGRPFAVVPRMFWTLVGFIAYTIAGIVGREHFSDILSNFLSILSYWTAFFMVITLEEHFIFRRKGGPLGGYNLDDWDTPSKLPLGIAGILAGAIGVAGAVVGMAEVWYIGPIGILAGNPEFGGDLGFELAAIFAGVSYPFLRWLEIRLVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Z8</accession>
    <name>A0ABQ8V5Z8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine protease inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_904901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0722">Serine protease inhibitor</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="143" mass="16252" checksum="ADC3494A63CBF848" modified="2025-10-08" version="1">MSLDTGRYLIHNGNNIVSRNLAEDRSLNPKRIVLLEPNDKIEFTWIIEKSGDEYILNNRGAPTTHIEDHVFALLIHQEQATKWTIEAVPRHGKNAYIIKGSDGKGWVAPEKVGEQIIYRTLIVGPSEPPTFPLNQVFQIIKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V630</accession>
    <name>A0ABQ8V630_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_587325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001251">
        <property type="entry name" value="AMP_deaminase_met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4472748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="788" mass="90710" checksum="981853AE829ED788" modified="2025-10-08" version="1">MNSPSPSGTLSPQSENSTGHLQIPETRDGFFGYTEEKSLQHIGEKYWAHRRGSDVPSEGPAASFASGSLQISGLHAAMAEKANSSSPFTDDDEEKSVAESTVHDTISAELLHMFQSLQKCLELRDKYMTKSRQRLGDNPRDYDGDFTGLNDECAGVSGVRPDANFAANQPPPWSPERWVIYPPPPPPHWHWTDMQQVISSDGRRSPEGEFNFKECHIPEGDSKEFAVDDTGVYQVYDNAAKKKARDPCYDIPSVREYFKDLDYVLSVISDGPTKSFAFRRLKYLSSKFTMYSLMNEYQELADMKSVPHRDFYNVRKVDTHVHHSSSMNQKHLLRFIKSKMKRTPHDVVIFRDGQELTLQQVFESLQLTAYDLSIDTLDMHAHQDSFHRFDKFNLKYNPIGESRLREIFLKTDNYIQGRYLAELTKEVMTDLEQSKYQNCEWRLSIYGRSASEWDNLAKWVVNNKLFSHNIRWLIQVPRLYDIYKANGSVKTFEDIIKNVFGPLFEVTKDPRTHPELHVFLQRVVGFDTVDDESKTERRLYRKYPYPRLWDTEQSPPYSYWAYYMYANMASLNRWRQQRGFSTLVFRPHSGEAGDTDHLTSAFLTGHSISHGILLRKVPALQYLFYLRQIGIAMSPLSNNALFLSYERNPLPEFFKVGLNVSLSTDDPLQFHFTKEPLLEEYSVAAHIYKMPQSSLAELARNSVIQSGFEMEIKRHWLGHQWYVTGSAGNDINKTNVPNIRLAFRHQTLIEELEMITKPLKVTHSKRAENGVGPRGMLPTADTVAAMGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6D2</accession>
    <name>A0ABQ8V6D2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_774753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF1">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="2">
        <location>
            <begin position="40"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4474809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="434" mass="47492" checksum="7154C5655C0213CA" modified="2025-10-08" version="1">MTSHSQSHPTIPPFSASFTDSNLKVARSIYFKTLIGGTVALTAAMFAIFSIYWGALWKSPEHPLQGWIVDFDQSTIGNAVVQALEESSALGKITWSQVPSSNFADPNEVGNDVVEQKTWIAVVVNANATSNLQSAVASVDSSYNGSSAITVYGNQARSENGYNAVLLPTVQAVLLATSQKFAQSYATNLASSSSSSNLTDLLARAPQIITQPVSFVINDLKPFDIPVATAMTYVGLIYTLILSFFIVNISLSARLMSGLETHLTTASIIRLRLSSSFVTYLFLSLFYSLLSRAFQVDFSRKFGAAGFVLFWMLNWAGMLSVGLALEAMLTLLTMKGVPFFMILLIISNVSVCFLPIDVLPGIYRYGYAFPFYNISCAVRTILFGTKNNLGLNFGVLIAWTAISCITLPFFQWFMRRKHISELNGTMEPDEKVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6N2</accession>
    <name>A0ABQ8V6N2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_870622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046732071" description="Protein kinase domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29867" checksum="0A930C1F54129204" modified="2025-10-08" version="1">MRFPSLFSQFVFGVVCLFAAVRTMPIEPSKGPSKSAAAAFHGNASALAESDNDSQNRHWEKWWGQLDQTAVEDLTEKIRERGFSVPRNYGGHNLAIFPLSPETREFESLPGNQIVVKLVDYDDETSSCEVFALREYAEFQKAKGQTPTFVTSGAIVMRKVPGQGLEDTDQWQEKIGERQGMLDKVFKNIQNFNYEFIEKTKLVHVDLNMRNFPVDDHMNVYPIDFGPPSIYPVECVPSRSEFDAWFSERFDLIWGTQQGGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V717</accession>
    <name>A0ABQ8V717_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000069">
        <property type="protein sequence ID" value="KAJ4476796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF121">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27040" checksum="71574E1810074E51" modified="2025-10-08" version="1">MVLGAALVTGAAQGIGRAIALRLAKDGFKVAVNDVASKSDQLERLAQDIKKVNGKSSHFVVADVSKETEVEEMVNAVSKTLGELRVMVANAGIITRSKTTIDYSADEWDEIFAVNTRGVFLSYKYAARQMIAQGNGGRILGPSSLAGRKAGLEASADCASKFAVRGLTQSTALELGKFGITVNAYAPGFTKTALNEPFWDDPGSLLRKYGLVMPSYFKLGEPEYIASLVSYLASEEAHYLTGQTISPNGGALFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7B1</accession>
    <name>A0ABQ8V7B1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Golgi SNAP receptor complex member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_772781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of several multiprotein Golgi SNARE complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GOSR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4478001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027109">
        <property type="entry name" value="Golgi_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR027109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4478001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="220" mass="24880" checksum="91DEAB0EB2D4B7C0" modified="2025-10-08" version="1">MSSYEQLHRQCRTLENLFDTKLASYSQLVSTISRPSEDVEAEGSRARWKDLEMEAEELLEKAKETNEQLAALDSEILSPSMLRAIQRHRELFQDNSRELKRTKTSVQNALDQANLLSGVRNDIDAYKSSAADSLLAERGRIDSSHRMTDDLINQAYETRADLARQRSSLSGINTRVGNALNTLPGINNLVSMIKSRRRRDSVILGIVIGICIILIISYLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7J3</accession>
    <name>A0ABQ8V7J3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_512761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000065">
        <property type="protein sequence ID" value="KAJ4478566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4478566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="53912" checksum="A3A9430524E30510" modified="2025-10-08" version="1">MDNPQYYQPLSHALNPPRSSSQPQFYKTASVEHQKTLESDDDDEGRVEEQLSRTSAPPSPKPPETAPENQHEPEPKRRGRPRGSKNRRGRVSSQTVVVKSSPPSHQPLHATGQGTNPPQLPEVTAQNQQYYEFQWRVLNLCAEFYGAAEELVKGTPALVIAQCYQMGPNSKVDPLIMLNEAKQNCDILLANPSHLITSPPPPMYPSVPTFYATGVPSSSSSSGAPTGPPTMISQPQTFVVPMGSHAYYAPPPPGQYPTTSYYSYPYGHPGAYYTPAVAPVAPPPAAPAAPTPIVTMTNSGTGNSGSWSDEEIERLKIMAEEKKTGSGEIDWDDIISQWGSTRSRHQILIKATQLGLKESSSVRGVKRRRDVDGDPISSAAPTPNATTVRNPSSTPSSTPVASPSLQNQPQPASSNSKASTSVPVPPPGLASQPWPMPVVAVSTSSPVNIGPSPSDHRVTSYYRPRPTDPPSRPSSSSGASQLPTVHRYMYQPNGHHSESAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7K1</accession>
    <name>A0ABQ8V7K1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_897590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="16"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4473200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="281" mass="30534" checksum="2AB2810384ACC7CD" modified="2025-10-08" version="1">MPLLRALLSSSNPPNVIVLTRPGSKNKDLLSDLSPVSPIVISVDYTDTSALTTLFKKHSIEIVISALASTGYKAQYNLADAAKASGSVKLFVPSEWGSPTEGAKDKGEDNIFAVTASFTEHLKLLDLPYTRFFTGLFMAYVPWVVGADVDGKVHIQGKGDTPFTVTSQEDIGGFVAHVLTSLPLTSPELVNASLRIQGQQITLRQYAQVANKPIVTVTENETIPGNTDEDKALKAFLQKHIEEGTATTGWDHRTEREIEGATGSANKLWEGHVWQTIERTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7V4</accession>
    <name>A0ABQ8V7V4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_922619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="238" mass="27383" checksum="0AB124DBD4C9095D" modified="2025-10-08" version="1">MFLFSLASSRRLHQILSMYLFFTAMLVNVLVFAAPMPPTYLPLYILAKFTIRLGRRVGTNGPLLSNKIGFAPDQQFVLFVGDRHMFQYHHDTGKISSEIDVVDFKTFGSSPRNPDPPFIQLGTDHEQDIFINFHEKEIMTVKKPSDTMSIYGVGGFWGLIQDVEELRTTTGVRFTSDLEYVDAVFVVLMKLVRADGKTNLLESEDYQGWQDIFNVNRHLRAGVYRMLGAWDDQRRCRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V836</accession>
    <name>A0ABQ8V836_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_771990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="713"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="742" mass="82829" checksum="A693B585CECB03B9" modified="2025-10-08" version="1">MTTPLPKRDERSAPKFDPKNEALLPNFFEEFERTAKAAGIDEDAERMKRAVLGYLDAKTMRFWQSLDTFDDDEKTWEDFKTEILDYYPGATGTAEVTTEELVRVVKTFKKKAISTTQELAEYHREFAVVAKALRTQGTLSEILIAQHYVVPFPESIRARIDTGLYVHYPTKKVGQAYTINKIRKVVTFLLSDASAPVSSGSFRSGDRTSIPRSTIKETPPVIKTEPKDSEDSLSRQVAALTQMMQQLVRDNKNRENGTREPREPRTEKNCPWDGCLAKALKECPDLADWIAKGKVERNERGFVQLRGGRDLPNETKYKRGLVKVRFERYFEENPSAKTWILDVPQPPGSPLAPALAGVEVSQHNAYTLHSYQGPSMLATAAAYTLQGETDPYEAAAVRDLIFKMETRRATKERSGSSSSSTSPPKPITPLASDPQPPVAKPPTDPEPTKPIPPRNTIPTKPPRPIIGKLPENYVPPQERTVGVQPKEDTRNYRYRAPIETDAAVERVIQTGMSSMDDLLAIAPEYRKKVKDSIMSRRIGVDGGMLEDMALLEPVLMLDLDLANGTHSTPVSQKSLANFFTDFGDAREGDGFYVARESHSIRAVNAIIGGRPAHCILDGGCSIVVMSDAACNAFGLAFDPEKRINLQSANGNTDWSMGLAKDVPFRFGDVVAFLQVQVVDSPAYDFILGRPFEILMQASYKNFLSGNQHLTLTDPNTHKTTTIPTVPREPPRFRKEDSREYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8N0</accession>
    <name>A0ABQ8V8N0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Survival Motor Neuron Gemin2-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_842796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000061">
        <property type="protein sequence ID" value="KAJ4480350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22852">
        <property type="entry name" value="SMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22851">
        <property type="entry name" value="SMN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047313">
        <property type="entry name" value="SMN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049481">
        <property type="entry name" value="SMN_G2-BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20636">
        <property type="entry name" value="SMN_G2-BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival Motor Neuron Gemin2-binding" evidence="2">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4480350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="351" mass="37946" checksum="E74F9B881984AEC0" modified="2025-10-08" version="1">MRPVVSYDDITLPYDSVSAVVQETSRIVAHNNNRTSTTNKSSSSKKRKRKSRHSAAATSGHHGITGNNNNFNGEEDEDAVYLEVEESRELTHDEIWDDSALIEAWNAAAEEYKAYHGPDKGWKNEPVHKSPLWYNTPPPSSKKQKTSHPLPPSVVDVAVTASVKGPVVSTGTEADIAIESDSKPIDFATFVPTHDAGLSLPGSVPRMMPEGSNGISKPDLSSHHTTALSSDPGPMVSQDEAFKRALEATYWSGYWTAVYHCQNQKKATESKSAEDVNTEELVDAGERGDEISFDAEMMDNDVKAILDISNDSTFEGEVDSGDGEGNGGGDEDGENDSLASSTEGDLVSTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9F5</accession>
    <name>A0ABQ8V9F5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_745415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="14625" checksum="816EA5B089126FAF" modified="2025-10-08" version="1" fragment="single">PYAKKMMTARKYVPLWYFLPDAAVEAKERSKESLDTNHLQFAVEDGDSLAGSTVSLIGSHSVRASLNAIPDSQLSWTQVMQAKSAFLNALGPGTWPDDFVAMFAGFYSNMDMHRKLQEQDGDQVLAHYHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA27</accession>
    <name>A0ABQ8VA27_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 9">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1 9">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_770024</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1 9"/>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4483980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4483980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="365" mass="41894" checksum="9CDB3C55388D70D7" modified="2025-10-08" version="1">MSSRKTSKPLPAFEIGEDYQLLHAIGEGAYGTVAAALHKPSGRQVAIKKILPFDHVLFCLRTLRELKLLKYFTETCVNENIITILDIIKPPSLNEFTEIYFIQELMQTDLHRVIRTQHLTEDHCQYFVYQTLRALKSIHSADIVHRDLKPANLLLNANCDLKVCDFGLARSIKTTAGKEPGAMTEYVATRWYRAPEIMLSFKMYSKSVDIWAVGCILAELISGRPLFPGRDYSHQLDLILDVIGTPSLDEFYAITSRRSREYIRSLPIRKRRSFATLFPHASSEAVDFLSKTLAFDPKKRMTVDECLEHPYLTQYHDPEDEPAATPLSPTYFEFDQHKDKLSKDQLKELLYEEVLSFKSVINETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VAD8</accession>
    <name>A0ABQ8VAD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_459338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="929"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1044"/>
            <end position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1085" mass="119150" checksum="53BEFED7041BEFE7" modified="2025-10-08" version="1">MSRRLTISSLLCDDNNDSSEPRIVPEPVVLAPHLRRSPQRVEGDSTRSSSQSTASSSSKIGLDALVHAASAVAAAEERSRLPALSPTSWSADSHYTQSSSYTYSQEHLQRHQQQLEQRHVHREQILGYNEHHRPGRKSDPLPGPGMRNILSPSVSTSDAPFQPSSTRPLAPRFPHEADEHLNKKRRYSQEDFMVDQQRENQAREYERLRQQEDTDRYRRLEEDRERELHHRTSQQETTDDMDRTRHRMTVNNPPSRSSLSVITSPTVASINTSPLLPSRRVGAGYDPVHENDHHARYNVPRTSSHWDRIQSPSQFPSAQHVQRSRPPMEIEVTERESEVLVEDGRVTTAKRTWNGHKEFPSHAPYNLLSQESQSRAHAQSIPSSYRESYPATLSPIISQERPQSQSDTPIHPVFPREILSPTSAASGRSPHFQHDIIHTSESPSTLHVQHIQRDPPLPVSLAAPQHNARESKSLALSHTHPQLPHIPHQVRDLPPQHRVISPVGRRSPPGSQAGRAIAAKKVEHEHQMPSLESVLRTGTPVSSSTHPIEEAQTKRDLLMAHVSTKEADLTVIKDQEPVKSKEREVKKKERKPLRTKEVSQLGPVALKLEDGTSRPTLTPSGTSAPRQIAPPPSVSLTSQTNKQRHQDEDPHEWLLEHYADDDRRKIKRPSSTLSSVAVITNSDPGRNSTTSPLTRKPTRSPVMPSTSSVSKRDDTQSDKDGDDAMMALEQELDAELAKGVVDQKGSTYDNDTMDVDVDLAVAELVDETLGIDASATVIIGGRQHLTDEESKLGIRDEDDSGREPAHKAQPNADDKAMDVDVEDELLSLLDDRPNSRMSASPQSVAPSAPEPPRSSKPIVTAALRMKHEEPTSRPPSPLAVSTGSPFRSSSMTGARQSSAKPSEQDDRASMPPPSTPIEKTEGAVAAAQAKKKGKPGPRPKARNTDGAMVGAPPPPKPRGKPGPKPKPRDEFGNIIRTPSTSATPAPPTTTVTQSGRASSSSTPAPTLVSRTASGSGAAAGSTSGARSRSTSAHPAGSVGPEVEGQTKEEEKTEDKEEEVDDKFYCLCKTKYDEDKPMIACDSGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB06</accession>
    <name>A0ABQ8VB06_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_769268</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="JANVFT010000052">
        <property type="protein sequence ID" value="KAJ4484623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF3">
        <property type="entry name" value="HOLOCYTOCHROME-C SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4484623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="270" mass="30317" checksum="AF8DC88267F53F4A" modified="2025-10-08" version="1">MGQSVSTSKSTGGAQCPVDHNSLKPASCPVDHNSLKTSSQTPAQCPVDHQNKSPSSSSTQKQLAECPVDHSSLNQMPTLSQQPSPNQTITLPTARTESSILRDGSTKWDYPSPQQFYNALVRKGWETPEEHIETMVEIHNFLNEQAWQEVLKWEKRATDNTADVELARFKGRPGELSPKARFWLLAGWLFPSRFNTEPPFDRHDWIVRRPGSGEEVRYVIDYYSAPPDPDGSPVFSLDVRPALDSFASMKERIALATEEVWADFRETKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB71</accession>
    <name>A0ABQ8VB71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_768921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4485118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17333" checksum="F597DBBB430C106C" modified="2025-10-08" version="1">MTIFCDACLDGVAFWIPELLLGFYAPISSSQTTVRPIFFYESLAVVSAVKWFCMTARSDESLKQNLRLTVFTDSSNTVDIFNTLRALPDYNGLLRFAVDELIAASVDIRVLHIPGEQNTVADAISRHDFDRAKQLAPGLSIEFFQPPRVTLGAPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBG5</accession>
    <name>A0ABQ8VBG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit D</fullName>
            <shortName evidence="5">eIF3d</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_768551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03003">
        <property type="entry name" value="eIF3d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007783">
        <property type="entry name" value="eIF3d"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05091">
        <property type="entry name" value="eIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016281">
        <property type="entry name" value="EIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA gate" evidence="5">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="580" mass="63584" checksum="D5048C5FA26D10E6" modified="2025-10-08" version="1">MSFSLPPINDNPDGGWGPSSSNFPGQFKFKDIPYAPYSKSDKLGRFADWNETTSDTRQNAVGTVSTQNTRTGPGGRRREGAQAFGSGTASAFAYFHVEDESSFSLVDNKNAPPRRGGTFIRGRGTARGGVGNYNARGGAQRGGRGGFGGRGGNAQRGRRGWRDWDKGGRARESSVVISPQWSMLEEIEFHRLAKLRLEVDEPENIDSYGRLFAYDKTFDRITTKTEKPLQQLDRIKYNTTTSDDPVIQQLVNKNTATIYTTDVILSVLMCAPRSVYPWDIVIVREGNSLYFDKRDGGPFDTVTVNENAADPPQDPSPPNPNNPNEKVLDTPSINSATSLSLEATYVNQNFAFQSVVETSPPPAVDFSNPNPFYGPDETEPLASCGYRYRVFDLSVQEDEDFKICVRTEVDAYLPGSGNPREGQGLVTIRALNEFDPRAAGAGGAPDWRTKLDSQRGAVVATEMKNNSCKLAKWAVQSILAGADLMKIGYVSRSNPRDAARHIILSTASMRPTDFAAQLNVSLNNGWGIVRTVADLCMKMPEGKYVLVKDPNKPLIRLYAIPASTFSGEDEDGEGFEDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBI8</accession>
    <name>A0ABQ8VBI8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_982123</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GnRH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000050">
        <property type="protein sequence ID" value="KAJ4486435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002012">
        <property type="entry name" value="GnRH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00473">
        <property type="entry name" value="GNRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046300729" description="Thioredoxin-like protein" evidence="5">
        <location>
            <begin position="16"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4486435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36079" checksum="8A2D9FFA5DC170FA" modified="2025-10-08" version="1">MIFWLLLGLFSFANGQYFSEGWKPGQAFTNEPLAPVPTVASGHVGEEPQSQQGSSLDSSSISSIFAKIGVNITSIASAAGLSSKAAYPWDPRIPLITDVNYDNIVVNEELTPEEEGNRTWLIVVSTSATNQGGGMSQFVDKIFDETYNETLIAEDMPNLRWGRIDYLNVTYLTTKWGVWQAPTFIILQNRGQTLRFVKPHWLRLREGALREFLTDGTYNEVPPWDSSFAPGGSNEYLLHYLGLVLTTIYNITIKVPRWILYILSGSVASFIIQLLHRPPKKEQLKTQASATQKAEAVHIPGTSAPAAAAASGSTPTQSKAKQRKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCJ4</accession>
    <name>A0ABQ8VCJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_886900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000066">
        <property type="protein sequence ID" value="KAJ4477912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053729">
        <property type="entry name" value="MAD2L1BP_domain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="441" mass="48660" checksum="C88AAEBFB67704E5" modified="2025-10-08" version="1">MSLRVITPLVVPHPLSDLSNSAAERATTSQTPSKVQISPKQVDLQTETSAKDINDSVPKIPRVCLDMDVIPDMMAARLATSLLGHVLFLKNQIPFPVAQLSRLPGGKAFQSNTRAAKLKHDLIDSFDTLSSHLDTTFTALSTAFARCSPTGAFSSGDNDAVEQSPGSQAYLAILVGPSIGTAKSKVIFAVDGLETKIWGVRDDLPRKVEAREEVEDESDSDAEEGLEETYETFDDDDEENSHSEPEASDSEDDSDVSSTSSRPNSPIPQPPPSLPRRVYPSTSSQTSPTHLLQDHVREQQKIRAADQLLSRTLAMADAEGRGMASELVPTQTHVLLRAPRRFSHPAWIPRPNFTNSMEHTLNDFLEETRLFVDPFLENKPKSKRTQKQKVEGVWVARRTLSLNAPSALMSGEQENADQGQDEEDEMIWWSWDGKIVGFSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCY1</accession>
    <name>A0ABQ8VCY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_867991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000046">
        <property type="protein sequence ID" value="KAJ4488657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4488657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="179" mass="19188" checksum="74DE1D17A4938786" modified="2025-10-08" version="1">MASFLRKFSTTASAAGARSNVFFDVAIKGQHAGRIVFKLYDDIVPKTAKNFRELATGQNGFGYAGSSFHRVIPSFMLQGGDFTNHNGTGGKSIYGAKFPDENFSIKHTRPGLLSMANAGPNTNGSQFFITTVVTNWLDGKHVVFGEVVEGMDVVNKIENEGSSSGTPRSKVTITESGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDC5</accession>
    <name>A0ABQ8VDC5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_501210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4479404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="763" mass="81167" checksum="CC5FA73597FC4EC3" modified="2025-10-08" version="1">MAEAKLRALGSKDNVKPPTASLSIPRKRISHRHSRSTPTVLPIPALSFSSTSSSRTSATESTLATPVNSVCNGNIPQIHMSDIADNSDDDEDNLDTTTPTPSPKARARSPARIRSATTALAGQSPSILRQLSLSRSEFFSRSLTPPPRARPSLAMSPEIHPRVDSVSGGRVTASKPRRASQLTSPMSLTSFSLPASPLHQTTMLPSSIQQRPLSRSEHLLRSALLKDEFAQGSSTSALNAPVKHPSKTHRRRHSHATVSADPPLDHSSYPLPAGFAVVTSPSSPSGRNTPTPRPRPVSPVHTKSAPVTHTMQTRLHPRSQSYAHALNEASSTTSTRLPLTPHEQVLRARLERVLSAGSVASPSSYQYGSTTRSNGSSSSADDDSLSHVSGHDLSGEDYGYSADLRQLRLKRAERKKHRASAPANGSGFLGWLWRSTESDEEEIPNPLFAPLAAGYRQTLQFQDVTDERRNPSIPNSPRTPRMNTSSNSNALNAPSSPYHTTSPQLSPSPSRLRSHTQPLPSSPNRSPYGQGYTYSPKPKHAFSLGSVPSVARDLSNVAATSGNGGLTGINGKGRMLTPPPTPPRDESVLFAEGLGQTDSPVNLSHDEHEPGSSEENANLEASLIRRGDSFTGKSGRGQRSLGLGRPGAKSSEDSVSSTASSLAEAIPSVSVGVDSSNATKSNDSALSPLLSPTSALSTTSSFNARTASLQCREIDGYISFASIEGLGEPPVSALPTDSGDRGSMDGDEQESQKKGLFGRLFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDH5</accession>
    <name>A0ABQ8VDH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_884556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="74"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4486824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="273" mass="29385" checksum="E5FB2E30F43D1445" modified="2025-10-08" version="1">MSSVSSSTSTSPSSGPSKEKLDSEGSVKDISVNSFPKDTEENSTTAQEITKKPSEKDAESIELNASGSAIPGFAASSTPWQAIYSPQYNAYYFFNAETNETTWENPLVTAPDSTTPNPALENPTDSSSSAVAPVEGAFDGAALSSYNALQAAAIAQGIDPSLAHLDPSLAGPIPGSSSGAYGAAAKFNARTGQFTRLDGRDPSHLSEYERAKRMSEFYFDVNAWEKQRAHEQDAEAEAGGNEKKRKRPSKKDLERFKEQKKQKKIAKTAWLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDI6</accession>
    <name>A0ABQ8VDI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HSP20-like chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_504367</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="5">
        <location>
            <begin position="4"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="CHORD" evidence="5">
        <location>
            <begin position="137"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="216"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4479479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="342" mass="37767" checksum="400D3BC6E3C4B3F8" modified="2025-10-08" version="1">MPRCIRKGCGKEFSEGSTERCTFHPGAPVFHEGLKSWSCCSDKNKPVLDFDEFMEIMGCVETDRHTNDVPDPESKAPATLTAAKEVAKAPSKVLEVSAASSDPAPPLATAKVVPATLPLVAEEEDDLSVSIAPGTSCRRKGCNVTFISDDENRLGDGEGTRCKYHPAPPIFREGSKGYMCCKRRVLEFEEFLKIEGCQTGRHLFSLKVNTDKKEEFTTCRLDHYQTLDQVHVSVFAKQVDKDRSNVKINEQTLSIDLYLPGSKRFSKTINLFGPITPEQSTVQYFGTKVEVHLKKQDTRSWTILEKPTRDLGNVALTFGVSGRTGTIGAKESVLDAQNSARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE29</accession>
    <name>A0ABQ8VE29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_833994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02883">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="78"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4491038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="292" mass="33015" checksum="ACE7D8A54D14E8F2" modified="2025-10-08" version="1">MSIFGSRSQHRNTNIHNSLPASSVARASSSSHPNTISSGSSFLPTLFPRHRSPRPQPPLNFSRYSSTSVPDGGWACEDFMVGVGMVVIQPTTNKMVLLYDHSGLKGRSYFLPKGRKDLGETLQQAALREAYEESGFKVDFLPLYKHHRQPIPPADRADGWKPDTEPIYMTLRKWGPRVRQDRIVNSGGEYFVSWFVGQIAENAVQQKGVGMPDEQAFESYLFTFDEALNMINPEERPVVIYAEHLYQQHFRIVAEFEKRRAKDQDLEGTERVAVDSEKRYAGESSSKLNSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF04</accession>
    <name>A0ABQ8VF04_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046379759" evidence="1">
        <location>
            <begin position="29"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="197" mass="21807" checksum="9B58F73648B0300B" modified="2025-10-08" version="1">MVFTFSLSLSRLLGPGLVLFLHILGALAAPLASNNAMMGPTAHLEQRGSYHWNNVAVTFLPYNREFSDKDNWAIKFGERMSMFHAEEVVANGVVTFRVKETLKTPVVGGSVGRVNLLNQNGKTSAFSKINAIKPTGKAQFLYEAMRILKEDYSLDQNAEDLGRWNELKRKMVDLTAQAQQKAKAQALAQSALALMPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFG7</accession>
    <name>A0ABQ8VFG7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mug135-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0612 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013902">
        <property type="entry name" value="Mug135-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08593">
        <property type="entry name" value="Mug135_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mug135-like C-terminal" evidence="2">
        <location>
            <begin position="157"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="253" mass="27979" checksum="8DC9B4A0CD991603" modified="2025-10-08" version="1">MLQRKLLISESTLRPIFDPGLTDEFNNIQCPQNPPTPAEVIEAARLAHRALRYRDNGAPPTSNEYISDEAVAACFYYEKAVLESAAGVAGAPLWFQQWNQASFVPLVNDVRTLKDDVRTLKVNVCTLKVNVNTLKDSVNALGLNTSTLLIQDGKDRNGQQNVNNSGPFYEIPFPDGRKPWGLSVNRPGHVSSSFLPNVILPRLDNQASIDNLTHNQSYAYFAGYYPNMPVSNTGPNTLRDWKLAIARAIGHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFJ9</accession>
    <name>A0ABQ8VFJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="272" mass="29980" checksum="FD0D95FD04F12A07" modified="2025-10-08" version="1">MSSTNRNSSNNYQTNQTAQGRVRFEEESTVYSHEATRNPRSTTSSRGAPRLQDTRSLYARQYSEWITIKLAKFTHNANSPQSQPAPNMTGNRGYIEVPQLQPPEQSYGSAHQGNPAASWQHSAYPGQFVGNSAVDFTPPTPQGVNIVPLPNVGENNYQEAWRRQASPYQYNPVADSNQPPLTTVWMSTSATALPSAPEGVNIIPLQSIGGNGSAETRRGRGRVSAYPSSSMRYPMTVNQSAPQQSFPMNTFPVNNGATQEEGEEDRRCCRFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFM5</accession>
    <name>A0ABQ8VFM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_868259</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="737"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="430"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="532"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="639"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="784"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="537"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="594"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="797"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="831"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="879"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="897"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4486872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="931" mass="96796" checksum="E16AD12E1AC6FF3E" modified="2025-10-08" version="1">MASGSYTSGDGSSFNPASYTRHFLGSPMSYRSAVGSYNSRLLGYPGSVGSVTMGSPMDIHRDPAVSNALRLFEFQDELCRNYTCCGLHLTDLHALLEHFEDIHVVCIDQPGGGAPQARISVPFEPQIIDAGGVPQPMPSNQLQNQQQSMHQGGGPVDPDDMELETPFPSATASAASSMPSSPTSTPSPPETLLATPLSTYSSPSNLIHNSLAAAYPGGYPGVKSQKSLPSSSPPSPRQQNSLHNTTNPPTSTQNPQNITNDANSLQRPNLALNLPGFPSSSSRPVVHSPFITGPPPSGGAGAWAHSHGMPGGVDMTYMGNIGMNGGLGIGGFGGNFHYQNPYGYNYSEGEPVGSENGTVDMGCVQPAMLFSTPSSPQSHPGDGADDEDADAEFDIDIEDQEKEVPLPVYDVQKEAKKEKVSIKTLSAKAANTKGKGQYSGNSLDDSTTPVASTNAASSGISVDTAKPVPRIGRPPTGGGGSGLLQSKPFKCPKPNCNKSYKQANGLKYHITHGSCNFAPPKDMEHVQAILERKRKQQQQQQTPQENPANVNPSPSASSSGANTPRSGMATPVTPSSLSSPFTLALSVNTGVVSTGGSNPSSALSSPVAPSSGSHFTGTNNFIPTPSSLSTALSSALSLSSPTTATSGYAEGTYQDGEETSLNRSNSYGQAVSQNRITNANASSSSLINALTPISAAATSNNTTAADSLTSLRSTLSSLPPSELLAIEAEAERQLKPYACGVGDCPRRYKNMNGLRYHYMHSGDHGAIGLQWLASGKHECLAQRGDKSAGKNKGLNTGTGSVGSVVSTAYPSAGRVGGTEREGRKVRGAAGSSSKPPSRASSVSASRTSTPVTTTFPPMPMPYSSATQGEVSATVAPGYQPTQQFTQTPSSQPLSTPAHQYQQSQQFTPQASNGSHPTPNYQSRLGYPAPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VG09</accession>
    <name>A0ABQ8VG09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_332732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4493187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61886" checksum="D7C54E742EB1F3D1" modified="2025-10-08" version="1">MTRKGHQKLFEPRVKVDNLALNERLRSSYGIIDNAKIKGLLNQAEEDLAGYDLEMERVRMAYEEEMHRLGLRRQGLHIYMTNLTALQSPIRRLPEELLSLIFLHCCKENDLTADYEGCRKAMAMTISCVCTRWRRLALPCPVFWSNLTITFAYRNSKEEEAKLVHKLSIYLKRSKSHPLTLELTAYVFEPTTHKALALIARESHRWQYILFRGDFFGGDNFPYLEPLRLPILETMIFDKFEDTFFFKEPHSEPFTSTLNLKYVVFGSLELGSGAIALSLPLETITSLDYASRTDIVKSLSLVKRCTNLRHLRIDLWVDYDSNDYSDLEIIPQILSIDTLEVDIYEARKHNNSLALFTFPNLVNLTLTGGAPPSFSRSFAALKSLLARSKCHLQVLTIREYHCLADTDVVTLLLQFPTLQELCIEEDNYSSKPQPISTSFITSLHTWKQSFLRCSSAPLVPQLRVLTLKTVAEDFDPSSFVEMITSRWLPDECSEREIGAVCLRSVELHLPGIADAKPYEPLAHIDKAGMRVVVKCEGGYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGR2</accession>
    <name>A0ABQ8VGR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_980881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="174" mass="18046" checksum="5CFA1BEE3B799384" modified="2025-10-08" version="1">MATRHSVVAVTSMSSFSTSRYLTSGGTSPSGASSSPHRSQNYPDIFSNSMLLSPQAGMQAAGVANGGYPYPCGGRYQAIPRSPSPSPSKVAMPTQIIGGSALGMSYDGSRDVGYTNNRAERQAANAERKTYRRMQKGLRKGLLSGMGKAEQSCGCCGSSGTLGHERSLGGGYAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGW4</accession>
    <name>A0ABQ8VGW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_834575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="8"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="515" mass="58012" checksum="83B3ABD26F62B5D1" modified="2025-10-08" version="1">MAAAFILFMPNEIQLEIFHAVHDAGDALRSVSQVCRLWRELSVNTSTFWTGISIDISSIDQGVALGDPYTIEFGRLVEVFPWPATLLRRSGFQPIDISINLDSDFDTCTFSHDIVNVPWLTGYAVVLARFLAFYAARFRRVEILSDDLHPVRFLSLTLFDMPMPLLEQWSVISDKPRLTVLPPPPAPTIFQRPVGIVPSIEHTDTLYPKLASLSIHGITYDWGQFIPRNLVTLNLGNLLFSHDEFKTLLFHSKDTLQSLTVSAMAIYLPAQHVPTDARITLPNLYYLAVGVTFDPTAPYLATQLDVPNLLCLEIHDITTESERTWDTDDHLQRFYLHVIANWPLKQLTHLTLGSAHCPMDPANLIALQQDFEAGRGPSCFPSVLTTLFFNCTGLRNLRLLEPDSTTLKSLNVAINLQDKGPGILPSSSLDFLHIETQNYRELAEFLAQMKIYADLDSARIIARFIPTILLDIPPAWGPYLRPFLSRKACAEIVNGEGYFEVESGRIFNLLDNLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHA4</accession>
    <name>A0ABQ8VHA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_882173</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="4">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="458"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="65578" checksum="42DA6BAEACB639AD" modified="2025-10-08" version="1">MTAVNITDVDAVLTIYNSLVELHLNWMLLKYDDNSDEFYLYASGSKGLPELKQSFKETSTVHIAFYNEESSQVQSRPGFALINYIPSSISGIRRARALVQSRRIGALFVKTEYATLTIDHLSNLTPSAIHQAVLHPDGVHNIRIERSASSPEPIDPQSTSESMIFPIRRSFTENRDPSVIPLNYSTPPKSQSLFSSILRRKRATPSTDVPWDSDEDVAPPTPPKDNDNVSRSNFTYTPGARLRSIPNSDLRKSLAEFAFISHPIPSSDDEVIVEHPNPPPKTLQPLSSNKPDGALFSIPLDRKWVHDTVYIPDPEERARRRKLVQQQRALEEQQALQQEAERQARIKEEKEELKRQEEEEEAWRKSMLEQELQEIKARRRAREQRAQEEDARKKREIETRKEMDRKRRMEEHEKLEEWRQQMAWEVEAEKMKEEDDRRRADAERKTKVQNMVKEVKMELRSSGWTTAWATLQTGDSLVWRRRYLKLVGSKISIYRSPKDMNQALDEVELRGQIVGLCEPNEGFEELKAIKHSFAIVFKDGRDPWALFGDTEEEKIKMLGMLQYAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHF2</accession>
    <name>A0ABQ8VHF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_896280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000048">
        <property type="protein sequence ID" value="KAJ4486958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4486958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="712" mass="80547" checksum="76539BD3EB67AB2A" modified="2025-10-08" version="1">MNHSAPLEELNLRVHRTYTSSDENKSERLTILSVEEDSPYAEVRSAVANFDDPDMPVSTIRAWVLGIIWTVLLAGINQVIVYRFPSILITNFVALLVIFPCGQAWARVCPSISVLKMPLNPGPFSIKEHVLSSIMASVAAQSAYSTDIIAVQRVFYGEIYSFLFQWMLTVSTQLIGLSLGGVMHRFLVAPPSMIWPNTLVQCALLNTLHSQQYAGIGRHRGPSRERFFLMGFIGAVLWTFLPSYLFTALSIFSWGLNPIDSDTYKTTRFQSGLGLSMITFDWNQIAYIGSPVAGWSEANVVVGFIMFYVIITPIFYYTNVWYSQYLPMVASHAFDNTGNSYNLTRVLTNGAFNLQAYKDYSPLYLPMNFVIAYGLSFIAIGSTVTHGIIYLRKPTLMHFRRSLQEQPDVHARLMTKYAQVRGWYYACVFVVTFAMACLCIELWPTGMSIWELLVALGIAGVLVLPIAMIQAVTNRQIPMNVFTELISGFLLPGQPVAMMLYTFGYITTFQAIAFTQDFKLGHYMKIPPLVMFWAQIASTLIAGSVQLGVQMWCVDHRNVQVFGTASIIWGAVGSRLQFTDGHLYYPLMYCFLIGAACPAILWVLTKKFPRSKLGYINVIFGGPAYVPPANSINYLTWAFVGFIFQHLVRRRRFLWWAKYNYYPLNGTIGMNTIQKWWGNTVYTRTLDWKSPPLRALAPGETFGYDFNLDREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHY5</accession>
    <name>A0ABQ8VHY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cinnamoyl-CoA reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_919097</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4494423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="334" mass="36180" checksum="50B7FEEDA98E6902" modified="2025-10-08" version="1">MSRILVTGANGFLGAHIVKEALDSGYLVRGTVRSQTKAEELRKVFPSDKFDTSVVPDLITGDYTEALKDVTAVIHSASPFTMDLSDPKDFLDPAINGTLNILRAAHAAGVKRFVVTSTVGTLPNRPESLFADTTYGPDDWLPITYEQAASGTLPGFMVYITSKKYAELAAWDFAKEHPEVKVTSVNPTIIYGPVIHPISSLKSLNASNMAIYSLINGSKTIPPDSVPIFCDVVSTARVHVKALDSEATYGKRVLFAKGPATMYQILQIIVKARPELADRFPPIPEVDPVAGKPISRIDSTIAMEALGIKGLELEETVLQTVDNLLELEKKLGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJA8</accession>
    <name>A0ABQ8VJA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_763203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="26155" checksum="019E0AA840F5FB5B" modified="2025-10-08" version="1">MEHACGEGCGSYIWGRSIHNVRIEHLWVDVSHYVSQTWHDLFTHLELHHGLDISNTNHIWLLQHLSESYKVFLSTINEQLTFWAEGWNNHQISQRNGPSQSPEDMFGFDMIANGLQGGSLDEVSMTNKELEVFGLDWDGLRDKVLLRSLRQNYNNEGSSSWLGQRGPPPELNQVVVDPPPGLFTLEQIAWMDEQLSRLARGPQEEDVVQLWITALAIARSMTGNTPTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJI1</accession>
    <name>A0ABQ8VJI1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_909813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF141">
        <property type="entry name" value="GH15225P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="411"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4494254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="628" mass="71838" checksum="CAB500472D541DAF" modified="2025-10-08" version="1">MNDRKRPALEQLSSVRHAKQQRTALLSVDGERQSPAVASTAALVSRWNRIYHDLKELGKDTILLLSGRVVASDSSEESLEQQGSSQTLSPSPEFLRQTGAAAEESSRVEFPPATPNTVHSFAASQSSLRPTSLYATSSYSSFPFPSTSPFTFTPRNRHSLPSSESSEISFPTFSSTHHQLPITPSSSLDNLYSSRRPRTKSTMGPPPDPSMFDPYLRSTSALEKNLQSLKMAQQPRLYKTRPHIYVERHKQEIRKNLEATKDLLFELARQKRGFKSGRKDFDSYLDYSYMLENAEKRPRFTSPSMIDLRSEYAFDDKKALSRRSSDSLSREQWLERKLQIAQKMFSGPKPPPAWSPSLDDLKLRQRSKDDLIDQRLRPPRLPLPSSLPPEDEGKVKSLLKQSGVIAKFAREQILDKDLVRLKPGSWLNDEIINYYGALILGRSDESKENGDNGIINGVANARKGKVLNVHYFTTFFWQKLTREGYEKGRLAKWTKKVDLFSKDIVLIPVNHNNTHWTAAAINFRQKRMESYDSMDLDRSAVFKVLRGYIDAEHRNKKGIPFDFTGWEDYILKDTPQQENGYDCGVFTCQFLESLSRGEETFNFSQDDIPYLRRRMIWEIGHSTLRTDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJT2</accession>
    <name>A0ABQ8VJT2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_918615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="842" mass="92822" checksum="614EEA3B76BA276D" modified="2025-10-08" version="1">MSSNSDCSPSCTPSPLLPPLTALGEVPSPDSESDGEVKQDQLAFTLESPSRPQLQLFETVFNTGKPLSGYCQDDPLWLLLAEVASPCTNCVKTPGKCKVLLNSPRCANCTSKKTCSLGKILQYRYFARRCDQDLAYSRRFLELHGTSAHQSTWGIPLSAWREYNAALHARTSSTSTLLELNMLDEKDTVEADQQELREFLALQQGEAVVAAKRKRDRSPLPVAGSSWKKVWSDAPKKCSRRRTPVAATIPGSPLRIRLVVPPSRPVVASSSPPIRPHSSPSLMEVLHRDLPMQGPSDLVRLAAAAEVHPGLVQQAGSSSPARTPIKGAGQDLLSSTMPPILRPALVPRNLASHPYRAENQCLAARVHLRESQLADSQRENSSLTSALRDTSHALKSRQREVEQLRSSSQEFLQHQEEYRCIVDHFNTLDRALSGPSDQSLLECFQKVEEELRITKKDRDDATGKLSTSSRRISELTTALLYQHGITDEGNALSTRQRARLEELQEEVHRTCGRAAFVERMIKEYPDEGYYKVVLPPLSQLEGDLVKVQADLRRVATLAHRLYRSDPATVLHHHNRYIGAIIEAVVAFLRHALETEDPNVMVHNFQLALDYMQLARGIHGDLHIRSLSSIQWFFNNAVDQNEGLYTLMLENSRFDSDRPFLTAAQHAGFTSPPPDLLEPPLHRRMLALSTALPHREGAGRWDDLVPAIPSDDQLTLDWERLMLQYMHHIIDTPLPAPDVATSISSVGPGGESSGGAGVGAEQSFDAGVAPMVEPRSVSSPIRTPLFLPEQESPTSPSPPPPSPSLPPLFGSVAPLTIDLTSNDEELYDAGDVDAGQVLKNEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK88</accession>
    <name>A0ABQ8VK88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_980054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045634234" evidence="1">
        <location>
            <begin position="27"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25728" checksum="7D478B6D3F155C0C" modified="2025-10-08" version="1">MPCFRAMFVHLFGLCIISSNVLSVVASPIFHDGALLVPRADNHPGSEASSAVSHPAQDDVDRFQHSEDGELYWDGDAVEDDSNTLIASGRPDNEVEDLAIAIYQSKGRNIPESEKKYWLCVGTKCLRANKDPKAPSDLLPDVIQGRGTLQELKNFGKISFKDIKHKRRILVNFGKGQRHYFVGNSNPTNWDYIAALLRELRRQSAEAQLVKQEVIEQYMKEEAKKNLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKN7</accession>
    <name>A0ABQ8VKN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_760538</name>
        <name evidence="2" type="ORF">C8R41DRAFT_760805</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35871:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35871">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4496948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="48679" checksum="E7DF7F1BA5CECA1B" modified="2025-10-08" version="1" fragment="single">REKREEILTSAFKDIDKLILSKKTNFVNGHDGLQATRARSIHSTLTMVVERKKGLIDASRIAAEAHNFAVEWGSRCIRRWTQDWIKTRELPHSNRGRHAKVYSLLSDPTARDAIRAYLRTNKWSLDPPKLKKLFANELAPDEAHEYSKQIISQEMPRGLKSFVEETLLPSMQCKPSHLGLSLSSMRRLMLREGFTYKGWVLEDNQPLKKKGPGRGIHQSDFICSTVGWLKDASVTLEYGKNHEGFWNCELFIKQLKEKFFPAFRAAHGPGYIAVVLVDNSQGHAAYAKDALRVSEMGFRPGGKQCRMRNGWFTCNGQKIDQSMLFPPDHPQYPDQPKGMQQRYLREHCDYTFQTLRENMPKALASIKIELIRKWEHRAWRFIDAYSDGLGAKDAVTQVKKFSSRRYTSHRRIPESLARAMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKX7</accession>
    <name>A0ABQ8VKX7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 9">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="1 9">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_294947</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="1 9"/>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023617">
        <property type="entry name" value="Tyr-tRNA-ligase_arc/euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050489">
        <property type="entry name" value="Tyr-tRNA_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006330">
        <property type="entry name" value="PRK08560.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264:SF4">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264">
        <property type="entry name" value="TYROSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006588">
        <property type="entry name" value="TyrRS_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="377"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4495444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="436" mass="48304" checksum="7C3FF4D10FD9C673" modified="2025-10-08" version="1">MEDPSSSLDLSPEQNAQYDMITRRLQEVLGGDAIKAILKEGKTPKAYWGTAPTGRPHIGYFVPLTKIADFLRAGVEVKILLADVHAFLDNLKAPLELVQHRTKYYEYVLRAVFKSLGIPTSKLHFFQGSSYQLTSEYNMDNYRLCATVTEHDAKKAGAEVVKQVESPLLSGLLYPGLQALDEQYLDVDFQFGGVDQRKIFTFAELYLPRLGYRKRAHLMNAMVPGLMGGKMSSSDPNSKIDFLDSPEIVKKKIKGAFCEPGNVEDNGLLSFAEAVIFPISQLKIDQAKGTGVMDEDGKEALSTDQRSFASDNAPEGTLFSVNTKFDGPMHFSTFEDLRQAFKDEKLHPGDLKPAMVDAINRLLDPIRKAFGESEEFRQTEQLAYPDPNAKQPAKKKKEKVYHPPPPGKGKNANKSDAVAEVPVGLESHPLEASSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL10</accession>
    <name>A0ABQ8VL10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ftr1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_303844</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4494421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="386" mass="42239" checksum="E6A4BBF99CA782F2" modified="2025-10-08" version="1">MTKNLFSVPIFFIAFRETLEAAIIVSVLLGLAEQIVYEDPGRFTQEHTVTSTTDESKQDNPEQDLAVAADEEVQRRRLIRKLRIQIFAGAGIGLLIALSVGAAFIAVWFTQAANLWANTEELWEGIFDVIASLMIFVMGVSMLKMDRAKAKWRLKLQKAFDGRTKGDKDGKAGKWVLLILPMITVMREGLEAVIFIGGVSLGQPATAIPIAAIVGLVCGLIVGFLIYQFGSRTTLSIFLIAMTNLLLLIGAGLFSRGVWAFQENAFNDLLGADVDDSGGDGPGSFRVQGNIWHLDCCNPEDNLDNSGWSIFNAIFGWTNSATLGSVLSYVFYWLAVIVTLVIMKFQEGRTTLFGHESSAGRARRIRREKAASRPIDGSSGSSTDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL20</accession>
    <name>A0ABQ8VL20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_226267</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009316">
        <property type="entry name" value="COG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024603">
        <property type="entry name" value="COG_complex_COG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024602">
        <property type="entry name" value="COG_su2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12022">
        <property type="entry name" value="COG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06148">
        <property type="entry name" value="COG2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 2 N-terminal" evidence="9">
        <location>
            <begin position="60"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="COG complex component COG2 C-terminal" evidence="10">
        <location>
            <begin position="526"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4497087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="894" mass="99958" checksum="647524D42F2B0A30" modified="2025-10-08" version="1">MSVLSPAASSSSSADPFQLERLAEELATRELSHPAQSYPQDGASHDLPIYTPLSHENPFLSAENFDVEEFLLSRSHTSLQDLRTELRDYLATLKEALVKLINDDYEAFISLSTDLKGEGERLTGLKQPLGVLKAEISLSKTELRGIQDEIMLKLEHRTVIREEKALLHLLLKISESVTRLESLLSITNPSQDEEPVEYEQFKVSATSNTTENTNERSPANKAKHLNRAAAEYTQLLYHASKARSENCAFVDEIQWKIDRIQSSLSSDLDALFASTLTAIAGDAKLSELEKNKILPDLTECIRTYDVLGLWRDAEEILRSEVMRPFIKKTVFTGALSAPHSPLLPHTPFRSSMGSGFPNSSSSMPPRTPFTPFTAFSTQQSAFPSSLGKTKSPYSRLLDDSDDPLAKLYTQILRFVERDFSSIMDIAEKVSVKSRSSTDPFQIDAAENGRKRDGLGFDIMANVIWNELGKAIMDDLGGFVFASGRPDEFRKNYEITQAFIRSLEFIAPSAQSVQSMRAHPVYSMFEKRWQLPVYFQMRWKEIVSKVEDALALPVEPSGKPPGAADSLVTPQATSVWVALTACWSAEIYIPELSHRFWRLTLQLLSRYRVWLNDVVQDTNYSSMNSVNTIHTGKISEANTRSPTPALSERPSLEAFSADESLLLRYVSLIADIKTLQSSTMNLWQEEICMMLPEPDGLDENDKSQDALENAVDAISALIRPMSSTVIVVLTERCIVPLNAVKKIRTDLRAKANKLLPTEPHPWITSVLRPLKVFFGLSGKDGIGAVLKAEYLDPWSKQIFENVCEKYISHVSTLKKAEESLRRLKRGPKNTTFSLFGSTNPRDVEGKDEERIRVQLILDVEALRKDAETLGIIPGNSEAFVALSNLVQSNDPPETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMG1</accession>
    <name>A0ABQ8VMG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isomerase YbhE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_761353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF7">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="364" mass="38536" checksum="3D847C1915AA928B" modified="2025-10-08" version="1">MVKFSILAGGYNTFIATYLFDSSAGTLDVAAKFPAGTNTSWITPHPTNSSIFYATNELSPMGALQSYTTTSDGVVSGPHDTVPSGGSDPAFTVALSTGQVAIMNYDSGNGRIFPTDSTSLKFDNDSAPIITFPPPVGGVSHPHMAYEYEGEVIVPDLGGDKLWRITRDDGPAHPGDWNITGLIPQPLGSGPRHMKIFGERIFVIHELASTLTVQPIPAPPNGTSDIIDSKLITPSGLPAGAAMAAAEILIPNPTSKFPTPYIYVSNRNTGVQDPRGDAIAIFEHVNPGKPDEGLKLITEVFTGLDQIRGMEIGLERNGGDEFLIAAGVAGSAGAVVYQRVDGGRNLTEVARNLDIPTRTTFIWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VN30</accession>
    <name>A0ABQ8VN30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_760833</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4497007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF143">
        <property type="entry name" value="FMN-DEPENDENT ALPHA-HYDROXY ACID DEHYDROGENASE PB1A11.03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="433" mass="46992" checksum="AAE940EF9C251E71" modified="2025-10-08" version="1">MSNASSDVIPQWGTYMREIYLNGKGPEPLGTVVFEEIEKKAIEKLKDLPGAFLYSGGSAGTWSTYTGNTIALNKFRIIPRMLVPCNNRDLRVTLFGVTYPSPLILGPVGVQGTFTAEGEYAPAKAAAKLGVPFVMSSASTRSIEQVAQASGNGPRWYQLYWPRHEEVTFSLLKRAKENGFTGLVVTLDTMSLGWRPHDLERSYLPFGHGVGTQVGSSDPVFMARLGRKPIADEIPEFPYDAVTKQKLLVDGDPTAKDAAQLGYAWLAEANFGFYRSWEDVKPLRDNWEGPLILKGIQHVEDAEKAIDIGVDGIVVSNHGGRQLDGAIPSIYALESIMKSEKVRAAQKSGKFTIMFDSGIRTGSDIIKAMALGAQAVLLGRPWVYGAAIAGQEGVEQVIKIILADLDISLAQAGLKGVADVLGRADQILTKVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNY3</accession>
    <name>A0ABQ8VNY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gelsolin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_894209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF51">
        <property type="entry name" value="PROTEIN FLIGHTLESS-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="38315" checksum="03CE0F9D01322729" modified="2025-10-08" version="1">MIISGNNAAVLSRETDIFYDAEVVAIVHRSKSKSNGLVSTTIWGWLGKNCEAGDLEQNKLEELSKRYGTNVILVKQYAEPSEMLRLLGNHLAVRQGKRAHWSADNTAMHVTRSRRGVIFIDELDLTIRNLCSGFSYCLTVLETIYVWYGRGSVASERKAALAYGRSLGENIVELQEGQDDGDEMFWMILGEEAFANANYWQWRPSAADINPRVLEVSEQTVKPVDFLQNISTMVHLVDCVWEYFIIVGSEARTQRQNIRIALYVASELVRRVGWQRPYIPPIHVVILPSQIPLDFKIHLREIDESSLNPQGVPEHMNLLTFEEAHDHLLRRTFWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VP37</accession>
    <name>A0ABQ8VP37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_160282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="312" mass="35650" checksum="F036F2449198E970" modified="2025-10-08" version="1">MQAQLPSSVLGLLATGCDFALTRQKEQEFIWNHKKPFRLTFVKGLFISMRYLAFVIHIVNIVLSSIWTVEFSNAQQASEEACRILLIFQIISCYTMLLLLQLILMLRVFALYNRSLRMAIFLFLLFAGRTAMSIYTSFGKSTHSPRHIKFGRYCIPKISLREQSIGNPTLVFIYGELLVQLVIHGLAWKRTIWDLRQYYSYPPPALLSVLNKDGLKVLMGISVAMAAVGLATLKISFPVTFIFPLFISLVSALGCRTILNLQRLDALTEPRTSEPHKELELSTIDHSSMTNWDAAWDLTTFYMEDSHPRDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPI9</accession>
    <name>A0ABQ8VPI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dfp1/Him1, central region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_818718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013939">
        <property type="entry name" value="Regulatory_Dfp1/Him1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006572">
        <property type="entry name" value="Znf_DBF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF26">
        <property type="entry name" value="PROTEIN CHIFFON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08630">
        <property type="entry name" value="Dfp1_Him1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07535">
        <property type="entry name" value="zf-DBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="75"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="514" mass="58316" checksum="B747151F39B9092A" modified="2025-10-08" version="1">MATTFRNPLSQRSRPSLASPRVTKTSVGLKRPRSPGVTPEDQPSNGATKRVKSVAEASLDKHRRRDQEEIEWREKYTRAFNAFKFHFSEDIQNTDYVKQLERRILQLGGTVEDFFSSSITHLIVRDVEPSRASDKENRHGQRSPTKKVGLITEVPLVYRRTVDEAKIKEWGVRKLDSVLSRCLIQPVILPTSGPLPARLNPSTSTHPTGQTRSLNKLLQSEKIHGTTERDPTQKRHDFAYFARGSYFVLVEDIHQELATIVTHQYTPPKKGSTRTPWPVLHCHPQSRGPFVPFDEKEKKRWEKAQKIEREDKIEAHERELKEQKLFQERMSREREARHRGFDLRRSVSMNNLRRRESLEAETGNEQCFDLGDPDSACASGYLASGNGGYIAASGNSVGITSTTGTTSTTESNFGLGSKLSAKLKAFADQQVPTSLKTGRRDSIKGNMGPPALPEGRVGVGLRRAKSTNNLKLPKREEGSKPGYCESCRQKFEDFKQVHFPDLYLYLHLFTRCFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQY6</accession>
    <name>A0ABQ8VQY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_101375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4498798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="74" mass="8402" checksum="7F4CA3DC68F2FE4A" modified="2025-10-08" version="1">MKALNAFSLASRGNEYIHQDLAESEQVLENEREQREHAEMVLGDVLRECKQPTITPALLTALGQTDFSQTLHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR23</accession>
    <name>A0ABQ8VR23_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_755804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="264" mass="30030" checksum="248AF53D1D9F938A" modified="2025-10-08" version="1" fragment="single">VGAHRRNFFGPTPTIAGELWKRAFWCLVCIDTQSVSCHCLFLIISSLCLKSFHSYDLDFPDCDDEYWVQPGEQAFQQPAGKPSTVSSWIYFLKLLDIFGLAQRSIYAVRKPERWTSNASWDENIVAELDVALNKWADTVPEHIRWDPHRQDPLFFALSASLYSCYYWAIMVLIQIHRPFIFVPGKGKGSGMKYYSSLAICENAARSCVHVFGRLHSRDGEHGYPSKYPSLFNSAIVLLLNLWGGRQLGLATDPIRVMADVNKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR33</accession>
    <name>A0ABQ8VR33_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cleavage stimulation factor subunit 2 hinge domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_818957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cleavage stimulation factor subunit 2 hinge" evidence="3">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription termination and cleavage factor C-terminal" evidence="2">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16592" checksum="C3278D6173BDEB5E" modified="2025-10-08" version="1">MSEQLIELMLQLKKTTPAAAKQILNSQPQIAYALMTLMVSMNAVNFEVFQKTLAEFSLGASQPQPQANPQPPPPQTYHRPTPPIYSQPSTSTYPSYASSTPAPAINPAILAAIPDDQKVMVMQILSMTPEQLAVLPPQDRANIMQLKSTFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRR2</accession>
    <name>A0ABQ8VRR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_916563</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Conjugated with ATG12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Preautophagosomal structure membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.190">
        <property type="entry name" value="Autophagy protein Apg5, helix rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007239">
        <property type="entry name" value="Atg5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048940">
        <property type="entry name" value="ATG5_HBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042526">
        <property type="entry name" value="Atg5_HR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048939">
        <property type="entry name" value="ATG5_UblA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042527">
        <property type="entry name" value="Atg5_UblA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048318">
        <property type="entry name" value="ATG5_UblB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040:SF2">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20637">
        <property type="entry name" value="ATG5_HBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20638">
        <property type="entry name" value="ATG5_UblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04106">
        <property type="entry name" value="ATG5_UblB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="4 6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Autophagy protein ATG5 UblA" evidence="10">
        <location>
            <begin position="36"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 alpha-helical bundle region" evidence="9">
        <location>
            <begin position="165"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 UblB" evidence="8">
        <location>
            <begin position="263"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="220"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4498312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="366" mass="40979" checksum="847B086658234C4A" modified="2025-10-08" version="1">MSTYGTTRHHHSPAANYSNRDRVTNYHTTLFRRLTWDGTVPLEIRVDPKELPANSDRNLECYFVQAPRVSYLPLLMPEIRRFFMDLVFDETAAKDLKDEEWWFETTEGTLIKWHWPIGLIYDNHTISASLKPSTSRSSANVTPLRLILHLASPPNDKLLLSPSPEACKQAFMGQLKEADFIRWGSTKRMTGLRQQDQDGLWEGIKEHNFDDYWRVASKVTPTTAPTRAQSPAPPSSSASMVNRPPSADPGGPSERDGAYNVRSIPVRLYLPDGPVIQDLVPPMVDDNTPRTLSHYLTDHIPLLFPAAPPAPPPSRTNPHPRPPPVPRLAYVLVQGIVMPLETEMAWLGGCLAGADGWVNVCIGINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRU0</accession>
    <name>A0ABQ8VRU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Casein kinase II subunit beta</fullName>
            <shortName evidence="3">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_121307</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4498671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="345" mass="38717" checksum="94B5E24BB3BADC38" modified="2025-10-08" version="1">MNVANQAELEEEEAISGTGEGDEIMEEVEEQEDGYTSSTPTSTLTWISWFCSLPGHEYFCEVTEDFIEDDFNLTGLNTMVPFWKEAMEMVLDVEPDEDTSKIPDVSIVESSAEMLYGLVHQRYILTRVGLSAMVDKYEAGIFGSCPRVYCMGTNVVPCGRSDMPGLDTVKLFCPNCNDIYVPPSSRFQGVDGAFFGTTFAHLFFQTYRELAPAPFWKAPPSSSMSNSPRLSTGSMAHTASTFVNPNPHGGQKRAAGYVYVPRIYGFKVSERAKCGPRMQWLRLRPESPDELDMVDWRGRWLDDEDDEYDEDDEEEEDRQMEDFDPVRSNPALFPLAAISSVSTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRW1</accession>
    <name>A0ABQ8VRW1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LCCL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_755187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20369" checksum="D0D9FC4EA4649EF5" modified="2025-10-08" version="1">MAVPAHITTLNLNGKFQMNKSLSDSPDDMLSAQGVGWIKRKAMGAASITVTITHSKNNAGVDTLSLVQVVSGGDPAEPEEKTLDWEEKTKEIKLFGGPCVTRSKRVSLDEVQESYLKEGWSADTLEHGCILVHLAYEGKHGWKTEQTWGIGEINGERRHIRRIALTGTKGEKLYNRIVYDYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRY6</accession>
    <name>A0ABQ8VRY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_816152</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF4">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="31"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="455"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4499143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="510" mass="55490" checksum="6C0C00587D17E564" modified="2025-10-08" version="1">MEFVERAVAENYRSLSLRADSTSFNGGDVSFIIVAGAMVLLMVPGLAFLYSGLARRKSALSLIWAVAASNAVGIFQWWFWGYSLAFSSSATNGYIGNLRNFGLMKVLGDPSPGSPLIPEILYSFFQMEFACVTIGILMGGIAERGRVLPAMVLTFTWMTLVYCPLACWVWGVNGWAFSWGVLDFAGGGPVEIGSGVSGLALAWVIGRRQEKELLNFRPHNVSLVCLGTFLLWFGWLGFNGGSAFGANLRAIVAIWNSMLAAAFGGMIWCIMDFRYEKHWSMVGFCSGTIAGLVAATPSSGFVHPWASVIIGIVSGASCNLATKLKFHFQIDDALDLFAEHAVGGIVGLFLNGFFGTNEVIRLDGVNTSIPGGFMDHNWKQLYIQFAYICATCSYSFFVTAALAKIIDMIPGLKLRSTPEDECLGMDEVEIGEFATDYIEIRRDVTDGLFMNSDSLSEHPVAAGDRHGRPDNQQSTMSNGNGHVHQGSDEIQHDSNGITDIKEKMRDSESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS83</accession>
    <name>A0ABQ8VS83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_136411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="275" mass="30312" checksum="CECA47C8C537E6B1" modified="2025-10-08" version="1">MAAVSPAEIAIYHSWIDAYLVSAFVELFMDGLYTALIIVTILVIASIKQKRSLSDYVIYASLFLLYAMCMVHLGSWAAHIHDAFINHTGDTSTVFAFFSLASHQAIVRDVMAVAMTLVADLILVWRVFAVWGSSWKIASVPLILTLFALAFGIQYIDLATKPSNLVSLKWITDVAGIYYGSTLGNTVISTLLILLRVHSLSGTKGINRYWRFLSLVVESAALYSVILIIYMPYVTGTDFATHAPTEIVQSVVIPITVSPSLSMNPCYPLEVIYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSB1</accession>
    <name>A0ABQ8VSB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_915455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="635"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="657"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="783" mass="85069" checksum="0F2E26CC21C1E42F" modified="2025-10-08" version="1">MASRRLNLHVSALNDAEYQLYTSSLADITLTDSQVDDGIEHDDAYFENISITVREARAWLRGRYSHISAAMLDNILRFFSPNLSQTDMLSGGQFFAALRLVLHVESGKDVDRALAFVQAHPSSVPISRPSSPPKSQTQAVSSTVSSSRRSSDSNNPFSAPPQHRTFNTNHNPFSSTRSVSAKSHDGATDSTPSKLPPLPPRKPAPPIPGFQPPPRHGSFVAPVGNPPPPPPLPSKPTLLHSHTSHVTSALMKQSLIASKNGKTWKQAEEQLEKERVLRVLKSSEVSSSNSSNSSPFTLRGRSHSPNKMGSSASSSSYTSSSDNNRAPPLPKRNHSKKPPSPPMSTTSFQQVALAGKPSTSSSHNPFKSSPFQPVSVIDPPRYASSPSTSPVRKSVDLPQLPGPPPKHPDQNMSYRKPPPPIPPNLSSSATSSGFHVIHKRTPSFTQLHKSAESFANDADQRDFEVIYGTKPKTASPYVSTFSRGSTDFTSSRNREGTASDSSNHFDRNVFPNNGNSPSRMFRSKSLHHPSPTSLANRLAAAELGDTERSPFSPLDDDTPDASPGPSPASRRRRPESVQVLGSNNNVLGTNEWSPPKNISPSGSSPNSNLSRHMSLSTPSPPNGAASLRRHQRKVSGSSSGLGLGQSPSTSDNPLKSLAASLQPQLLSMQQQLQPHLDKARFKAEAGLSKRGFVRDHKSLIRPREEEEGLMRDEREDRWEQQCVEDDDSNEDVEDYERNTQGGQEDRTPRSLSIGSRKGSAASVGIEKDNLKWPVGEEEGWGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSB9</accession>
    <name>A0ABQ8VSB9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_815068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="105" mass="11018" checksum="21893A6DE3BE6840" modified="2025-10-08" version="1">MSLFRTAISRVSATSSLRAFHASPAASKTVTEKVSEMAENVNKKLGQGLASAIEKGEDATSSTKESLRSAADKTKEGATVAKQKANQASAGATEAKEDFKKEVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSR7</accession>
    <name>A0ABQ8VSR7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_755858</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044244">
        <property type="entry name" value="TTC27/Emw1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="557"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="591"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="897" mass="101560" checksum="040F47CB3E0F1F1E" modified="2025-10-08" version="1">MTEMDVVAIEKSLLNGHWDNSFPHTPSVDVAQAVVRGRFGEALTSSYAQQLFQFRLADTLKNSFNISASLMQDEPQNELLRLALAVACLHAFLQVNWTGPDLDFQPLDILLQTESHNLSNEALNELAISELALGGEPAYHLAQHAIFLRLTQILLDAPYHHCQTAIWWRLRAHLVHQQVIDEPVILSDNDMTTFEHWQSPFALDSPDLNGRLLLEHGLLHHIFQQDKIAAEYFVKAARATDLQYELTGALGKRTKFQQTELSQLVLLAESHLPDVSPERTEVLSTNEPDQAVVPETLALNDDTLLEKTEFTSSRPLADPSSSSLYRIDPSNQPPLHPLDQCILLSLCLNVRNTSPLHGLTSEQMSPYVARVISHPRNWTIHTMALLLRSRLEANRTRTVERSTLQLQALVDQMPATDVEAAPVSERLRYLHSISLPPKWELERELANRFISLGVIRSALDIYERLEMWEEVVKCHVSLDRPDRGITIVKDLLAGNKVESEAVISREKASGAVDSMKRLQRFDSVREAKLWCILGDIEPEHAVEHYKRAWEISKNTSGRAMRSLGGFYFARAEYRLARECLQKSVKIEPLLSKSWFILGCACMRLEDWQGAKEAFARCVTIDEEDGESWSNLASMYLRIEESNKDGDSAGTTVVTHNNNQLAFRALKEGLRRSYDNWRMWSNYMIIAVDLGELAEACRALGRVVEETSNKAGGVVLDEDVLDRLVIAVTRAPSDPQEAVASSNSDQVQYSLNPNEGHGLLPRVLDLFDRIILPRVSSTRVFRAYARLLTWMGRWEDTMKAWMDAYRESDAGKLTRGELDTVAAVGDDMGRRVWRDAVGEVEEIVDILRNVGARLASSSTKKWRLQAKSVVRSFMARTRENFEDDSEWKRLEELLDGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSV4</accession>
    <name>A0ABQ8VSV4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_879382</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="208"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4497635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="439" mass="49443" checksum="D21DA2C6ED0C64EB" modified="2025-10-08" version="1">MTGNIEVQVLLELITKSATEALDEYGKYGDSVPSVYETNTHPLDEHKMSLRLKKAIRNLEGACDQLCATLAPPLHTIVNRAQDYYWSCLRVAAQNKIADLLDHTTGGMNLESLAHESGIEPSKLRILMRTLAARHCFQEVSHDVYANTRLSLVLHSQSSHTSYIDLLTKEGQESAGNFQKYLSDNEYSQCNDSTHTVFTHAVKDTGFHGTVYDWMKVNGDRRAVMSSSMPSMNSVMGTLSIIEGYPWEKISTVCDVGCGNGSFVWSLLQNFPQIHVTLFDLHETLEAAKQAAGCLSQELQSQIHFQPGDFFKDSLPKAVDIYYLRNIIHNWPDNDVLTILVSIKNVMGPQSRILIHDYTMHSFQNQSPHHSLDQAPWPMLPDFGNGSMRLHYQDLTMLFMYNSKERTLEEVKNLSQNAGLKLEQIRDLGETTVLEFGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTP3</accession>
    <name>A0ABQ8VTP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">chitin deacetylase</fullName>
            <ecNumber evidence="12">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_755896</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="12"/>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF98">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="14">
        <location>
            <begin position="108"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4498855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="338" mass="37573" checksum="6B7329D2F6B7653F" modified="2025-10-08" version="1" fragment="single">CAPYTYPPVADQMGSFPPLWGPASILPDDSAALAMWNSISSDIPTSIDTKVVDFFFRLIYLIDPLCRRNLPPSDYSSDDPDCWWTYDQCTTPKLSGLPPDVADAPEPATLGYGFDDGPSCAHNVFYDYLQSQNQKATFYFIGSNVASSPLEAQRALTEGHEICVHTWSHPYMTTVGSEDAFAELWYSKDGDLPIQMIKLAVGVTPTCWRPPYGDIDDRIRSIANALGLQTIMWKYDTADASVDGTTITDETVETNYNDFLQTANSGAFNSTGAILLTHELNNFTMSEAVKYYPQLKSAFQYIVPVGVSLNKTQPYIETNYSLPTFEQCKHCIALINIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTV4</accession>
    <name>A0ABQ8VTV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_813569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="201" mass="23068" checksum="B10994FC5ACFDF06" modified="2025-10-08" version="1" fragment="single">GLQYMHRNNVAHRDCVRNNMGMDANPMFTCHRRAFHHSCTCCPPTHFLIDFGQSRMYNPSQPCPSEYALKPGSYTPPEGDADIPCDPFATDVYILGTMIRTSFLDGDSNSYKPGVHGFEFLRPFVNDMIADNPSNRPTMNEVASWFSSIVGKLQWWKLRSQAVQKDEFNLTTLFHALYHLFWMTLMMLLFKPAIPSPKDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUC0</accession>
    <name>A0ABQ8VUC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">5'-3' exoribonuclease</fullName>
            <ecNumber evidence="13">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_812761</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Possesses 5'-&gt;3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.</text>
    </comment>
    <comment type="function">
        <text evidence="11">Possesses 5'-&gt;3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with RAI1; the interaction is direct, stabilizes RAT1 protein structure and may stimulate its exoribonuclease activity. The interaction also stimulates RAI1 pyrophosphohydrolase activity, probably by recruiting it to mRNA substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="13"/>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017151">
        <property type="entry name" value="Xrn2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037239">
        <property type="entry name" value="Exonuclease_Xrn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 13 17" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 13" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="14" id="KW-0862">Zinc</keyword>
    <keyword evidence="14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="16">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="408"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="628"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="947"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1155"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="635"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="969"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1019"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1155"/>
            <end position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4499973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1190" mass="132047" checksum="7449FFAB4204AFF5" modified="2025-10-08" version="1">MGVPALFRWLSKKYPKIIYPVQEEEEVQVPDENDEIVVIPPRMADSNPNGVEFDNLYLDMNGIVHPCTHPEGRPAPETEEEMMVEIFKYTERVVNMVRPRKLLFMAIDGVAPRAKMNQQRSRRFRAAQEAKEKDEQRKESVLLWEAMGKELSEEEKNKVAWDTNAITPGTPFMDLLAASLRYWVVSKMNTDDGWKGIQVIISDASVPGEGEHKIMDWIRRQRANPGHDPNTRHVIYGLDADLIMLALATHEPHFRVLREDVFGESNSNACRKCGQEGHYAAQCTAELAQIQKKPPSEKKPFIFLDVAVLREYLEVELDVPQAYFPFDFERSIDDWVLLIFFVGNDFLPHLPSLEIREGAIDTLLRIWKQELPRMGGYVTNHGRLELPRVQIILEGLAKREDDIFRRRREGEERQEANAKRRKLEEENSKNGFSAGPSSSLSLTASTSSLTNTTTVTHPSLPPRPDFAARADSIGLGAKPNAESIQNIPAATQALAGSNHDVVANRRAIRMANMSAAEVLKAELAGLVPVKPTASHVDNVPNVLLPSDPEPSMIVSDTTATPSVDITMTVDTEDEVPGFGAQSVTDENAPSVSTDFDIPFSEKNNVGIFENGTVGADDVEFDPNLAGAKRKHDEMNTEETDETVVVDDDEPPVDGPNSSLAFKVNPDGTVSQEDTVKLWEPGYRDRYYRQKFDVEPNDKEFRRQITKHYVEGMAWVLCYYYQGTPSWQWYYPYHFAPFAADFEDVDKMDIKFEIGQPFKPYEQLMGVFPASSRKHIPEPFHYLMTDDDSPIIDFYPSTFEIDMNGKRMAWQGVALLPFIDPVRLLEAMKEPYTKLTEDEIRRNTWGNNSIFTSDVHPIHPFYEQLYGKRRPKEPLQIDHNLTKGVSGSVLPNPECLPGSTYLTPLVEQNLPDIKNDRSLSVFYFFPKQLTPHRSVLLPGVTRSPRILSANDLEHARNGGRGRGRGSGYDRGGRDRGGNDRNDPFHSRPPNYGNGRGNSRESYRGQYRGDNGSYNDRGRGRPSPNNSYSNGYGNGRDVSSASNNSYGGYGGYGGGPAREYGNGPMGSYGSAPTGGYGVGNVRGGYGGTSRDYGGSGGNAGGSGARDYEGYGGYGNTGGAGGGPAAYRNSGGYGNAGGNFPGASRGMGSYRDDNHSRYSASGYTNPTHGNGGYSNAIQGGPYNTPSRGRGRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUY7</accession>
    <name>A0ABQ8VUY7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi apparatus membrane protein TVP38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_531700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17342" checksum="3B5B7B9D0E55EC9F" modified="2025-10-08" version="1">MTASAIPPATSIGPEPAPISTLMQYTPIIASNIVKITSSSFHLTTWLIRSSFSYPKRIILSPLSVFLSVSLYLLAPVIVFVQVLFDVLVLTPYNSVIYLVDAIYPLYVFCGVACITGVILGVLARQLVFWLTELGKIDELPEQPIKLVAEKVKWEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVB3</accession>
    <name>A0ABQ8VVB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_811002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="177" mass="18858" checksum="47AB5748ADDE5CE3" modified="2025-10-08" version="1">MGVLSVARTQAQFMSFLITIPAILSVTIGPIEVVAKGGGAHVTEKSEPSGESLGLKTPTVIVHHGSHECIEQNTGQIVACPSDLTAAAIAGITIGSIIASLILAFVLWKLFSFYRKRRERKRAARANPSTYQQLEGHVHPESMQDTGYASSVSDSGTLIGNDEKMSLSDSVKGYMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVD5</accession>
    <name>A0ABQ8VVD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_864697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000015">
        <property type="protein sequence ID" value="KAJ4498505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="816"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="963" mass="107606" checksum="018838B6762613A3" modified="2025-10-08" version="1">MSTAREQAGVSVRLRIRYHKQKPGYSTFDPDGPPINTNKVQREISRLGLPYCRKDAIEVPRLGQVQCEWYFEKGSKTPQTMAYKLRPESDSVRPKEIDDWMQEFSIFGFTATCKERGCPPQLIVKHPEDPHFGGNLEMFPIIPGPKRFTKHPQEYPASTRAWGVKPNYDEYPKLGRYSLSSITKPSSNEHQRSPLSSIASTPPQLRSPATTLVDHESSSSLVPPPTSSTLVGDPSVDGSWPTLYTKDADYSPRYKREREEDDFVMRKHSLPSASKRSRWDVAPTGNLLERFRSRSTSPSHKRKSNCPPSGPRSMVNNVVKNSGHGEDFTINPHRYRSSSESHHDYREPHSERWEGEDIARWPRRTPSPSPPSRRSPKISDAYINPHVHSSQSVASVPARKMGTNNNEAPVTTSSAAISPSSLLTIAPVDLTEFLTAFSTATASVVPSSSASDSLPISSHHNASSNSTSSPVPNGESSSSTISMSDLNSLIKAFPAVSSRPAPQEQAPSAEGAGESTLSQTYALASSSMGTYVAPAQLSYGQYGYSYPPVHSNSYQYPYPYTYQPPHDGSYNQSSSLMPVVTAVPVTPAVTTGVPIPSFDSGGNINEPRIKEESLNSFINAMNVNPSHGEIEASSFMNPGVARIVQLRSELLSLRNEIRERGKKEKIVLAELAELAEKLQTDFVLGEVDGCGFQGFGIGSELGLGLRDDDKIMEKPSSSEIETELRSNLLIMQAQLTSERNIRRKVDQERRDAEFAKREAEHALKETEQRLSDAEQFMSEAEQGRKNAEYALSEVENAKKEVQLSLKEAVERRREAEQLRRDAEHAKITADDRRKDVEQGRKDAEHDKRKADDRRRDAEQARRDAERATRRAESDKHDADDRRRAAEHRLHDAESAKLEMEQRWKEAELARKEAEERRREADAFVADVKRECREPFVVPALMDVFWNVSKVTTQTTSAANEKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVY7</accession>
    <name>A0ABQ8VVY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trp-Asp repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_756417</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000014">
        <property type="protein sequence ID" value="KAJ4498700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018983">
        <property type="entry name" value="U3_snoRNA-assocProt_15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924:SF26">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924">
        <property type="entry name" value="UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09384">
        <property type="entry name" value="UTP15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="126"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="260"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 15 C-terminal" evidence="7">
        <location>
            <begin position="383"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="536" mass="58976" checksum="CA2F5B23F3569951" modified="2025-10-08" version="1">MDYQPVIVKVHPRPSSSKSSPEARYWRQFKHPVFVKEYAPVTSVHFSPTKPHRYAVTAATRVQLYAPRTQKVTKTISRFKDIARSGCIRADGKLLVAGDDTGLIQAFFFRSTKRNQRLKESILRTFDSHKQAVHVTKFSSLAPTQVLSCSDDTTVRIWDVPSQSCTTTFTAHTDYVRSGQSSTSSPHLHLTGSYDATVRLFDSRSGHCEMVMNPAGGSTGGNVPVEQVLMFPSGTVAVSSAGSILRVWDLVAGGRCVRALSNHQKTVTAIAFDSTASRLLTGGLDQMVKVYDVSTYKVVHTMRYPAPVLCLAVSPDETHIAAGMTDGTLSVRRRNPKPSETQFDASLAAAVLRSGTFETFLGGTLPAIGLGTVKGKGKAKPLGDVNEFRIESRRAKRLKGYDKLLKGFKYSAALDSVLRKQVPPTTTFALIQELIHRDGLRIALAGRDDVLLEPVLRVLVKHATDPRFGEMVCDIAGLVIQMYTPILGQSPLIDSLFLRLRKKVQTELRFQKEIRRTKGALDMIFSAVASTNLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW31</accession>
    <name>A0ABQ8VW31_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C8R41DRAFT_810114</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="13">
        <location>
            <begin position="43"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="190"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="14">
        <location>
            <begin position="449"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="549"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="631"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="10">
        <location>
            <begin position="678"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="11">
        <location>
            <begin position="1051"/>
            <end position="1136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4500583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1139" mass="127579" checksum="4187D5BDEAAD8269" modified="2025-10-08" version="1">MDETEETGWDDAGSRWRGLGLTDPIKTVEDKWLLLPAFLKVKGLVKQHTDSFNYFVDVDIKNVVKANNKITSDVDPRFWLKYTDINIGFPDRNEVETVDKRVTPHECRLRDITYAAPIIVTVQYTRGNKIVQRNVNIGRLPIMLRSNKCVLTGKNEAELARMTECPLDPGGYFVVKGTEKVILVQEQLSKNRIIVETDSVKGIVQASCTSSTHGGLKSKTYVATKKGKIYLRHNSIHEDVPIVIALKALGIQSDKEILLLTAGNTEAYKVAFSANLEDAAKLGVFTRQQALEWIGSRVKVNRRVMGPRRPAWEEALEALATIVLAHVPVNGLDFRSKAIFVATMTRRVLMAMNDEKMVDDRDYVGNKRLELAGQLLALLFEDLFKTYNSNLKTAIDKTLKKPSRVNEYDAWHTMQFQGDHITSGFVRAISTGNWSLKRFKMERAGVTHVLSRLSFISALGMMTRISSQFEKTRKVSGPRALQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDVEEEPIIRIAYMLGVEDISLSTGAEIYRRNTFIVNVNGTIIGLTKYPKRFVQQFRKLRRARRISEFVSIYINHHHQAVHIASDGGRICRPIIIVDKGRPRVTSEHISQLKQGQFVFDDFLRKGIVEYLDVNEENDAYIALYESDIVATTTHLEIEPFTLLGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIGYNQLNRIDTLLYLSVYPQQPMVKTRSIELVGYDRLPAGQNATVAVMSYSGYDIEDALILNKASLDRGYGRCQVLRKNATLIRKYPNGTFDRLADAPFDENGQKAKKYDIIQEDGLAGVGERVDPGDVYINKQSPTNANDNSFTGQAATVPYKNTPMTYKSPVAGNIDKVMISDTDNDQTLIKVLIRQTRRPELGDKFSSRHGQKGVCGLIVNQEDMPFNDQGINPDTIMNPHGFPSRMTVGKMIELLAGKAGVLNGKLQYGTAFGGSKVEDMSRILIENGFSYSGKDMLTSGITGEPLEAYVYFGPIYYQKLKHMVMDKMHARARGPRATLTRQPTEGRSREGGLRLGEMERDCLIGYGATQLLLERLMISSDKFEVNACQECGLMGYNGWCTYCKSSKKMAQLTIPYAAKLLFQELMAMNVVPRLILDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VW73</accession>
    <name>A0ABQ8VW73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_751597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="104" mass="11182" checksum="33F2ECAB91B80A62" modified="2025-10-08" version="1" fragment="single">LSMTLKLTDDIKKEIGQHFIFGFHGPTPFSGKGKDILTLTGPGYWAGNVIFMKRNVVKTVSEHPIDSHGRAEEIASHIAGLQQHARDSGQSIGLGIGTDQEGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWQ4</accession>
    <name>A0ABQ8VWQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_892777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF74">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="40"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="55272" checksum="8E31DBCA253A19A8" modified="2025-10-08" version="1">MYEDNKESLHEQDIAPSPVTWDGPNDPQNPQNWSLRRKWIITLVTSGVTINATFSSSAPSSATTRIIEQFAISSEVSYVVTSVYLLGYVFGSFFFGPGSEVVGRKRILVVTMCCYTLFILGQIFAPNIQTLLVTRFFSGFFASSPLTVGGAVLADLWAGKDRGLPSSIFSGSVFLGPALGPLVGGFVAESSLKWNWIFWVMFIFAGASTLVMIVLLPETCPLVLLSEKAKRLRKQAATPQIAKAIFTEHERKESTLGEMVRVTFCRPFLMLAEEPILVLVTVYMSIVYGLLYALFEAFPIIFMERHGLSSSQNGLIFIGVGIGSTIGAVLNWHLTETLYVPHYARWKGFPPAEYRLWGAMVGSPALVIGTFWLGLTGNYESISWAAPAVATIFLGFGIFLIFTSFLTYLIDTYLMYCASAFAANTVIRSLVAAAFPLFTVQMFQTLGIGWAASLIGFTALLLAPSPFLFYKYGARIRAKSKFAPCIDLKIAKELEKSKFFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX39</accession>
    <name>A0ABQ8VX39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_812034</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17961">
        <property type="entry name" value="DEADc_DDX56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF21">
        <property type="entry name" value="DEAD-BOX HELICASE 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="44"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="344"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="324"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="619"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="635"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4500172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="671" mass="73977" checksum="0289059B5CEC62F2" modified="2025-10-08" version="1">MVDAHLVDAKATFSSFSHLLDARLLRALADMGFARPTLVQSKAIPLALEGRDILARARTGSGKTAAYCIPVVQKILSTKSALDLEDLSRQATRCIILVPTRELSEQVSSYLKGLCKYCEDIVIANAAGSTSAHLQRTLLSDKPDIVIATPARGLALLQSKSLVASHLDSLVVDEADLVLSYGHDDDIRQIFSGAYLPKVYQSFLMSATMTEDVELLKGLTLRNPAILKLEDGEDEAAHLSQYAVKCSEVDKFLLTYVILKLKLVRGKSILFVNDVDRSYRLKLFLEQFSIKSCVLNSELPLNSRYHTVQEFNKGVYDYIIATDESDAQEKDEEEGNSEDGADDEDEDEIEELTSTQRDNPSSSSSSTTQTAISGSNAENSRKRKRLESADSKSQSQKRTKSQSETSGKTKSKKSKHDKEYGVTRGIDFIDVACVLNFDLPSSSRSYTHRVGRTARAGRTGMALSFVVPRDQWGKNKVVGSLPSAQHDEKVFSRIEKEQGARGSKLMEYKFDMKQVEAFRYRMEDALRSVTRSAVREARIKELKEEVLNSDRLKAHFEDNPLDLEYLRHDKPLHPTRIQPHMKHVPKYLLPKTAPAPVPGGAGVEATGVVEAEGDKSVGFVPFKKTNSHASRGRGRGAGGRNGRSSGRGGMGGRGSGRGGKKKSDPLKKFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX57</accession>
    <name>A0ABQ8VX57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_278849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4500977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="90" mass="10481" checksum="E8B83F6B233F5E2E" modified="2025-10-08" version="1">MLSPRLFTPFPRFQFPRPSVLSISPGSLLPCRARLYTVDTAVNNEEPSPLRGHGGVIRREPYWYKIPIWKDVTETEFLDYSWQVKSAEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXG0</accession>
    <name>A0ABQ8VXG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_808030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="454" mass="51004" checksum="B348B4D99BB30D56" modified="2025-10-08" version="1">MEETTHAQLYYDAQHQPQYIVHHIQYGTPSNFTQTVDKVLLQEGANLVQQVRTEKIWHNVEIKARYNTPALIISSRIVTLSQPPPPAIIPVASPVVTKALRDWLEPPTDEEIYALDELEEFESTDLSGLLWITYDNGSQFQGKKRSLPLDSEHSEDFDRDKPSKKILRLDSDSLLRVIPQPHIQLSKSFIPPRFDAIQAYDRAQTISLPPYTGPLPSTNDNFSRRAWIIPARGYLPSAWSESGASSAVVLDPQEPGFSLEMTTTGSTIKWSHFALKEFWKYLNTLRDLNKLGSLGISFQPAQSASLRLRREKENLSSLGSPDAHQGLHVAESLSQSGQSSTTSGASSSLRDCDYFKVYHDAKISMHLRRALDLFTFRLGSNEEQSVHLGQSEKAEFFEQSRESGVTSSPSSVYSKATENSEGEGRPKRKKPKYCLLRGARLVLVDERSRGMLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXL5</accession>
    <name>A0ABQ8VXL5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-mRNA-splicing factor PRP46</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pre-mRNA-processing protein 46</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_286338</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the WD repeat PRL1/PRL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045241">
        <property type="entry name" value="Prp46/PLRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923:SF0">
        <property type="entry name" value="PLEIOTROPIC REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923">
        <property type="entry name" value="WD40 REPEAT PROTEINPRL1/PRL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="1 4 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="138"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="222"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="264"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="349"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="434" mass="47497" checksum="EA4F1C6E3A394350" modified="2025-10-08" version="1">MSAHALPPLEPQLRHNAKRTRAVFASCPDDSITDEERSVRLRLAVKINDEFRQFKELPPALLSQQGAIGPARPKETRKMITANGDAETSRMIAKIDNTPVAQPSTFSSTKLSHALALHKTTRTIKPTYHPPWKLVRVISGHLGWVRSVAVEPGNKWFATGAGDRVIKIWDLASGELKLSLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLESNKVIRHYHGHLSGVYAMDLHPTLDVLVTCGRDASARVWDMRTKANIHTLTGHGGTVADVKCQESDPQVITGSMDSTVRLWDLAAGKTMVTLTHHKKSIRALAIHPTEYSFASGSAGGNNIKKWKCPEGSFVFNFSGHNAIINTLSVNAEGVFFSGGDNGTLTFWDYNTGTPFQNLDDVPQPGSLEAEAGVFCSTFDMTGTRLITGGADKTIKVYAEQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXM7</accession>
    <name>A0ABQ8VXM7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trichodiene synthase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_913702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the trichodiene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024652">
        <property type="entry name" value="Trichodiene_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06330">
        <property type="entry name" value="TRI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="317" mass="36009" checksum="4B91874451C9C3E6" modified="2025-10-08" version="1">MSTQPSEIQAMNVAKEDISSAIRSFLSRCSIPYRKVPMDLPFLELCYNEAAKRGYTVEGSDPLKPFIPAGVTIAITSYAHLKDTSVQVWMALYTACAIYCEDIHQKDTTAMAVFFERLMRGRPQEDRTLDAFADLILETSRHFPRITANFMVSSTLNFVNALLLEDQTQGLKFSTHASNYPAFSRTMSGVSELYALAIFPSMETPLESFIQALPTLMVFIVNVNDILSFYKEELYGETVNQISLLALCRDLSKSHAFHSLIHETVEAHEKIIRILEPDREALDAYKEFARGYVEFHVSLDSRYRLNELEFQPVLSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXQ2</accession>
    <name>A0ABQ8VXQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_862809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="133" mass="15236" checksum="93692CACDF315F3F" modified="2025-10-08" version="1">MTNQRSRSAKELRALYASQRARGVSLADGPGFLYAFVEYGHRWKIGMTDNYDRRKAEWDQSLAHILLELKCFKRPRIQCTQCVTSKNSSSLENGDEFGEGRFGQCLCALDLRKAFKSPALLNHQEPLEISEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXR9</accession>
    <name>A0ABQ8VXR9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_190607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="531" mass="60283" checksum="9C253529DCFFA5E5" modified="2025-10-08" version="1">MLSNNSSQLRSPIADRSCSFAKFSDPSQSENEGSTPEPDLCTCTPGAKHLCWDVDYEVYGVIHNNDIGCITCNDFASHIHRSRQQKVRGIEEAYAKMHEHHDIMWRRGLKEGACRYSFTAPLDNLQVLEEELNIAQINQAKAEEELKYLTRVVLGQISLVEFLSTFTHPTFATREEFWLSMSDTAAANTTKGLWSDDVNVENSILAQDSSLRHMTPDFHLKSSAEVSDIRRRADTSSQVSTNNHVCDHSSSSTALPRPSPSTEHPVISRHIPNLRPGEDIPGYYEGNLRTRDLREVLTTLFDQAHSGDADALAKCKALCREAHMVDTPDRTFGMRHVLIHWKKPALPNSSLSRTSRRTERNRHRDRRPGHSSDTSSVVLVNPKLTDSPEVWFEYLKMHSLSWPNGVRKQSNGDPWMADLRASRMFAQFRPLHEDMTYIRNQFTFATLSLFTDKGRYKFLVKQLGLRICPVAKYVPFTDQSGGSGNVSEEDVARHYATCGVTVQEVENEVEGWAIQYKRERDQRPSQTRSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXW9</accession>
    <name>A0ABQ8VXW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription activator GCR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="46664" checksum="FE6F837FA89C6342" modified="2025-10-08" version="1">MPPQLKRTLPWADAHQDEYNEDFAPYTRVRLVMQNGSYETEIDLLRLKNAELEARVNELESDMERILNIEMDDVVLLKEDMLSYYRQYRESQLEIMELEEEISKLWADANHQSLGQSPLEEGTLIRSELGSLEEKQLVAHTRQVDQGGVTSFEKQGMGRNVGVDELPAKDCIPEYVPDLRDVSQTNAGPDLRDCAGASSCSEFDEHIDGSSENISNMNSTHSTSSLTSLDTLPYPTGAPSLGWFFEAFHYLNTALGPQYIGLLQEWVDYERKHHWLNPHKLAGFSPEKRPTVLLDWMKNRPRPLPKVDKRGFFTPNFAEEVWAWWASLQPQWRLLDEGGLPVSFEQFGDDLSPLNKHGRNAWVGLLACIKWWGIGLKHYASDDHELYLSSWHSIVADMAKMLGKLVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY98</accession>
    <name>A0ABQ8VY98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_807108</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="370"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="610" mass="69727" checksum="0BFB765287C21D21" modified="2025-10-08" version="1">MALGLQPKPGTRVTEDILSIRLPIRRSWPIIFSWLSFFTTFFVEHDFKFYDDLQPETGVPSLRTVAQLFCLLLSSNIIRPVEFRSTPGAAEMMVRVHMYVFTIRSSPDSSVQRPNRKSALEASECGLAFSDGILAEWDDFWEEIYGDVFTKLVQTRLSTIIVRTLAHLSQEERLNYGLLRSWFCALTDILGWSVTEPVFNEISHLPSARYTSVVLRRLSADASNPNRTLTPSQQTNLQAVWYHALEFLSESFHFGGYTNIILALKSGLLLTLWNLSLAAETHPWVIQSSITCPRYIDLVKLIAGSSMYRSVQRCLEKPLQTSPFADVDIDSVIPNMSLATLTVWRDFKLLCVSRMRLRKYLETKYSFCSNDKCTTNSPQVRLCNGCKVTLYCGLSCQKQHWRNGHRAECLQHIKDAEAHLPRPAQERDYNIIGCIIQTELWEDRDRLLREQSMYRDQHLADDSAVYINRIDLTTSDARASVWTLEEAKANTEFAEEDWNFLIQGFHTMLRHQPQIEGDSEEVGPIITAIFPHPGQPSYMNMILTRPKFEAQSDPLDNNNDPELDSETEIRTSVIENNVGLSRFPSLRMGGGRFLFPVLGVHIKGPKQQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYD3</accession>
    <name>A0ABQ8VYD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_956886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1079"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1202"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="580"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="743"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1204"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1243"/>
            <end position="1257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1306" mass="144559" checksum="4EC689B850848671" modified="2025-10-08" version="1">MWRKLTSALKHGEQDTASTSTVSQGDVMGKVLEQHPNLSMFHPAPQENAPNSNSPPPSPTKSRRSMFKRGSRMPSDDDERAPSPSLPKLSLGIPKKVKSSLSLAGNQSQSSLSRASGRNTLSAATAEANRGLSLDLLRSPLSPNAAFDSIRSSPPESHQRPSIDTLRTLNADADDIRPPTPGILQGSVRSILRDPNTPGTGRNVRFFSRDAYQAVTPEQSTDNEYPPLSVPPVIPTGSAIDLSKPSTLSSIVIRPSSSPKNARPSVTEVFSPMRQDSENTSSASPPVPENDTSNLLDMSQEIQLSAFSPPGLGFDIDLDKVLDLPLSDDDNKDLVPNAMTSTPYRGPLRLKGKESAVQDSAQPSVDVVDESIFHSKEKSPRLPSILHDRSHSFSFGQTVFFSMADASKRSSTSSAVPSLTSTDTKSSPSPVSLQSSDSPSQSSIRSRSRALSDTVFHSMLRSSPISSKPPEADINDESSSELVVYDPAKPEPDPFSATANTYYTPQTMIPVTPPRGLPNHARKTSREDSIIVSLQTQLALQSELCGQYETDLRARDEMVQILGQKVNDLEKEELKRKGILRAWKKKVAELERTCRFLEEEVEGSRQESMDRSIMDEASSEALRMLHRQIASLERDKGDMARREEALRDEVQALENIVQDRSEEILSLKETVWSRDESQRELQQGLREAQEQIEQIGNISMVTMDLASVVGDGKNDDGKEEERERHRLAEVEWEKQRTEMIMTTEKAKAETVALEGENEKLRQQLKTTDDELTMLKNELEAQWGHSEKASERIEALEEEKREIEKERHALSGDVEELQERLGVVDGQKTDMEHECQSLTATIEQLEEKIGNMEVEWEESENRRADLEDAKKALEDEMHQVTEELQQQLQSAKDQVRYKHEHAERIAQTMKESEIRIAELELERQYSLSEISRLESNVKQCDTDVGTYSSRVVDLEKEIETLRERLSNINRDHARVMNEQERALQAATEHDGETTEQMKDLLKRQGEQNAELRMNKDKVNNLQAELDRLRRQVHTLQQESADKEVKIVQLSKQHDHAKEDLMQMNMALDSKQQELELLKRRHNVRGTAGSTSSTPAPSRVSRRDSAVFSTPSTSRPSSVISIGSDKESNTGKSTVTKERKLSSESVLPKMNTLAKSTRMNGPVPTANVSMGPPSTTKPRLAGTMGPPRMSMGTPTPIARVASLSRSTTTKPTLVSSSTSSGTVAHHRRSSALAGGSGSSTTTGSMKQPTSMPSVPTTLPSAPVTPSPISNLANLIEEKENLDTLHNLDATPAKADRGDRRRSMIPTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYM4</accession>
    <name>A0ABQ8VYM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_203912</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4501414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="51848" checksum="2245142FDA41E5B5" modified="2025-10-08" version="1">MPKDLPGFYFDTQKNRYFPLSSRPSTSPQSTLSSSKRSGSSVEVDPPNTPRVISHHTRSAQTLNQRLLSSPVPHCRPFVNHDTQCTRIVSTSRFDFSQTASFGDITEFCSATSDNGSTRRYIGDNKGWLYTCSVYSDISFDNRLEALNQYPPTDSPSAQTYMWPAEINLHSHSQVSSIKISGQKCVATCFGPVTKVAVQDLHVSGRTTLITLNQVHDVRVSHLQDNALILGAKGKAVYIPNIDISGSVQHLSNPQNSDVFALDRDENLIYTGLRNGSITRHDLRVSSNNHDGQLLFHSRFTPSKNSTSPSPVLYLKLVKDSQLLVSQMNGELCTYDTRFPVHSTPSQIFTGHRNSVTQKLGICIDPMHEFLFAAGEDRCIRGWSLRTGKALHGTSSVATCVPASTSRSSSSSTSYSDLTQFRNPFNTEFPTPIPTMQVTEESDGSLCLWAGSRQTLYQYFLGQYSKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYX3</accession>
    <name>A0ABQ8VYX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2-hydroxyacid dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_752063</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF257">
        <property type="entry name" value="GLYOXYLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="68"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="5">
        <location>
            <begin position="122"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4500414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="36847" checksum="6ECA22F887FA3C16" modified="2025-10-08" version="1">MLPRVLICGTITWADEDVKELLGPIADVVRFDSIDRSDFLKGFQPGGKYEGTVAVFRDNNLTDKIGIFDQSLVDGFPSTIKWIAHNGAGYDQIDVPACKAKGIIVSNTPGAVDDASATTALYLLISTLRNYAISERSLRELKWKPNGLAKRSHDLTGHTLAILGLGGIGMRLAELAHAFPMRIIYYSRHKVTDAPDWCEYFENVEEMLAQADVLSVHVPLNPNTVGLVGEKWIRALKKGAIIINTARGKVIDEDAMIRALEDGHLASVGLDVFPDEPEVNPRLLEFPHVTLLPHMGTETRDTQHKMEVRALKNIQDFLNNGRGIDVIPEMKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZF0</accession>
    <name>A0ABQ8VZF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_892346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF42">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="546" mass="59124" checksum="99AA1846851EEABE" modified="2025-10-08" version="1">MFLLSAFVSVALGSQIGFALVPGKASSFAGSTSTFQFPPADVTATASLINSFFPDASEVGFAGPTPTGDEAESIATAPALSPVKGYFPLVRPETSDKKGKAFDVVDSWANLSPMQSVKSFGLDNATERIPEGCKINQVFLLHRHGARYPTSGSSPAAFASSVHSAAGNGTFIATGPLEFLNTWTYKLGAEILTPFGREQLFNLGVGFRVKYGDLLKNFTGLPVWRTTSEERMVDSALHFAAGFFGVQSYQNSYYQVIEIEQDGFNNTLAPYDQCPNANNNISSLGGEATKTWNNVYLVDAQRRFAQFLPGFNLTISDVAGMQTLCPYETVALGYSAFCDLFTEDEWKGFAYGIDLDFWYGDGPGNPAVSAQGIGWVHELVSRLTQTRITTFDSTVNETIVSSNITFPLNQPIYVDATHDTVISAILPAMNFTSLSAGGPLPLDHIPENRTYKVQEISPFASRLVGQVLSCPASDTPTHIRWVLNDGVLPQNGITGCGDNPDGLCELNTFIAGMKQRIKEVDFDFDCFANYTFSLANDTITNGQFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZL9</accession>
    <name>A0ABQ8VZL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_282630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="65"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="300" mass="32894" checksum="9AD247ACD903EF5E" modified="2025-10-08" version="1">MPPKTAKIKNALKSAARLPVRRRRTVSSSSDSPTATLPVTTTPATGHTRSFKKGLRVGRISLGNGKGSGRNMQSPLEGESPLALLRVQVVACTDLLAKDRNGFSDPFATISLPPHPTRHSTPVSKRTLNPTFPAAQSTFDFPIYLSLADRLGVLEVVVWDKDYFGVEKIGMGRKEYLGEVGISLEDWFSIREPGEQLRALGWFEEGNTTFSLSLASTRSNTNAQGSVQLKIGFVEAPKHQAHHQRFSLAKETVGAAREGIEGVFGKEEKYPDVEVDFEEVYGELLKRSRPSLVNIPPPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZR4</accession>
    <name>A0ABQ8VZR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_805992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="71" mass="8017" checksum="543139EB4DA6591E" modified="2025-10-08" version="1">MSAFVDCWCGACLLNVTNHLFVNVLIAALLRIVMPQCNYFAIIVLMYVSRVIRSICSCSVFWFEVIEAVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZT0</accession>
    <name>A0ABQ8VZT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="142" mass="14910" checksum="AE9F8070DCA350AB" modified="2025-10-08" version="1">MWSTPVRSPSRTPSPLLPPLTALGEVPSPDPASDGEVEEDQLAFTLESPSRPQLQLFETVFNTGKPLSGYCQDDPLWLLQSLGPSCFILLASGCVSFNPSAPSYLPGPPPHLPVLPAPMKPSAAAMAGVSSDGVCANDVRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W065</accession>
    <name>A0ABQ8W065_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="5 13">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8R41DRAFT_11222</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="5 13"/>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943:SF1">
        <property type="entry name" value="GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11 13" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="9 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Galactose-1-phosphate uridyl transferase N-terminal" evidence="14">
        <location>
            <begin position="37"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose-1-phosphate uridyl transferase C-terminal" evidence="15">
        <location>
            <begin position="233"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4501716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="395" mass="45185" checksum="6D0AD7EECBC6B8D7" modified="2025-10-08" version="1">MAEIFDPSTHPHRRCACLAFFLNTHNQKCSFDFFADNPLTNEHVIVSPHRNKRPWLGQVEPPQNDKLPQYDPACYLCPGNTRAGGKKTEVYEHTYIFENDYAAVLPPPMPEAPINPHHLLTTKPIGGDCDVLIFHPRHDLTIPRLLIEDIERIIEEWIKIYVRRGSEEGIKHVQIFENKGAMMGCSNPHPHGQIWSFTNVPTLPAHEMANLIDYSHSVHPPSDAPRGPHGKPCLLCEYAHTEVNIGGTDRVVVKNGHWVAVVPWWAYWPFEILLLPYRRHIPSIFHLTPEEKTSFADILSKITKRYDNLFSCSFAYSMGIHQRPIPLSSPEETDEDDVAHLHLHFSPPLLRSATVKKFMAGIELMAESQRDITPEQAAQRLRECSEIHYMDVSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AV32</accession>
    <name>A0A9W9AV32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8J55DRAFT_534542</name>
        <name evidence="9" type="ORF">C8R41DRAFT_893704</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000007">
        <property type="protein sequence ID" value="KAJ4489604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AV32"/>
    <dbReference type="OrthoDB" id="10261046at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4489604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4499057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="188" mass="20776" checksum="4B4BECF306610B31" modified="2023-11-08" version="1">MIHAVLIFNTSGIPRLTKFYTPVHLSVQTLVQKIFSLVYSRPAGLCNFLDAPELEPYLAQNEEGERWRVVYRSYATLYFVFVIDGAESELGILDLIQVFVESLDRAFENVCELDLVHHILAEIIQGGLVLETNVDEIDDSVQLAAKLRRESYASSNPLALGGGLAPRGSNLQTPLGWLTGKLTGVGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AZ48</accession>
    <name>A0A9W9AZ48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8J55DRAFT_500205</name>
        <name evidence="11" type="ORF">C8R41DRAFT_810779</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000003">
        <property type="protein sequence ID" value="KAJ4493926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AZ48"/>
    <dbReference type="OrthoDB" id="423462at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089701">
        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000066">
        <property type="entry name" value="Splicing factor u2af 23 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="44"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4493926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4500268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="226" mass="25693" checksum="E0F50CEFC4357037" modified="2023-11-08" version="1">MASHLANIFGTEQDRVNCSFYYKIGACRHGDRCSRKHIRPPFSQTILLPNVYHNPAHDPVCKLNEKELQEGFDAVYEDLYIELAKFGHLLELHVCDNVGDHLIGNVYARYEWETEAQAAVDNLNDRWYAGRPLYAELSPVTDFRESCCRQNENGECNRGGFCNFMHLRLASKDLVSQLRAGQRLERKLNPPAAQGGGGWEPGKREGRARSASPKRGGNGEDRWTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9B3B3</accession>
    <name>A0A9W9B3B3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8J55DRAFT_413904</name>
        <name evidence="10" type="ORF">C8R41DRAFT_768364</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000001">
        <property type="protein sequence ID" value="KAJ4495932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9B3B3"/>
    <dbReference type="SMR" id="A0A9W9B3B3"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000329">
        <property type="entry name" value="GTP-binding protein rhoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4486799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4495932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="194" mass="21569" checksum="D9FB877A2AF3C71D" modified="2023-11-08" version="1">MSEIRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAVDSPDSLDNVQEKWISEVMHFCAGLPIILVGCKKDLRRDPRVIEELRKTSQRPVTPEEGMAVAQKIGAKHYLECSAKSGEGVREVFQYATRAALLSRPGKKKGSKCVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DKV4</accession>
    <name>A0A9W9DKV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor SLT11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Pre-mRNA-splicing factor slt11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C8J55DRAFT_124751</name>
        <name evidence="17" type="ORF">C8R41DRAFT_820424</name>
    </gene>
    <organism evidence="16 19">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLT11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000022">
        <property type="protein sequence ID" value="KAJ4475246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DKV4"/>
    <dbReference type="OrthoDB" id="10259600at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000006">
        <property type="entry name" value="Putative pre-mrna-splicing factor rbm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048995">
        <property type="entry name" value="STL11/RBM22-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF6">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21369">
        <property type="entry name" value="STL11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="15">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="14">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00069020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4475246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ4497978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="321" mass="35558" checksum="0A9D3B796C5B1D40" modified="2023-11-08" version="1">MPPKLDINKAGWEQSEFPILCETCLGDNPFIRMSKQEFGRSCGTCARPFTVFRWNPGSGMRFKTTVICQTCAKIKNVCQTCLLDLEYGLPTQVRDTALGFVNEAPTSDINREYYAQNMEGKLEGNKSGLDTGKAQSAGKEMLKQLARTDPYYKRNRPKICSFFVKGECARGSECPYRHEKPVDNELSHQNIQDRYHGRNDPVARKIMGAHAESQGLKPPEDPSITSLFLTSLSPDSTELSIRTQVLKSLPTVQPAELKSVVHVAKSRCAFINFKERNTCECAAGAWANGLEIDGERVAVKWGRSKASKPPAVVTSSLAVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DRJ3</accession>
    <name>A0A9W9DRJ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM3</name>
        <name evidence="11" type="ORF">C8J55DRAFT_560283</name>
        <name evidence="12" type="ORF">C8R41DRAFT_894471</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000014">
        <property type="protein sequence ID" value="KAJ4481746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DRJ3"/>
    <dbReference type="OrthoDB" id="29543at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000036">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="10"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4481746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4497793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="92" mass="10235" checksum="291FEC67A6CCFB19" modified="2023-11-08" version="1">MDGSSSGIQEPFDLIRLSLSERVFVKLRGDREMTGILHAYDGHMNLILSDVEETIMIVNEGEQATVNVAKRKMDMLFVRGDGVILVSPPSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9DUM8</accession>
    <name>A0A9W9DUM8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like modifier HUB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8J55DRAFT_507319</name>
        <name evidence="4" type="ORF">C8R41DRAFT_855804</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000109">
        <property type="protein sequence ID" value="KAJ4467269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFS010000009">
        <property type="protein sequence ID" value="KAJ4487228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9DUM8"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01791">
        <property type="entry name" value="Ubl_UBL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000054">
        <property type="entry name" value="Ubiquitin-like protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4467269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4487228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="73" mass="8396" checksum="EA9C5E6DE5C1A8F4" modified="2023-11-08" version="1">MALIEVIANDRLGRKVRVKCSPDDTVGDLKKLIAAQTGTDHTKIQLKKWYTIYKDHITLSDYEIHDGMSLEMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWW5</accession>
    <name>A0ABQ8UWW5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_927247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000153">
        <property type="protein sequence ID" value="KAJ4463779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="69817" checksum="3AAD15EB7EF58725" modified="2025-10-08" version="1">MSFSCPYCGHFCKTEAGRCSHVKQTLCNYKPGLVPLSTLLSLLSSASLSSFPPAPGSSSPHLPSPHLPSSNSELDPWTEDDQEDFMDVDHIEANSVPYQIPFPNASQIVGQGATFMDDFNDDHFADERGTNLYYPFASRPEWETASFLLNSSLSMQEIDVYLKLDLVQKSTTSGCKLEIKKYEDFTPLQLQNSFGPLLSRCYRSPSRSHEKPFDMRLSPFHSYANFEDSRKLVKVYDSWLSGDKAWKMQSQYPEGATLLGIVLSSDKTTVSVITRNRVAHPLLISLANIGSDLLSKALLHLFSLLALLPVPKYVEQKTSIRGVLENQLYHKCMDIVLEPLKVTAHIGCMMSDPVGQLRVCYTPLARAIVDTPEASLIACTDAIDSIQARNIFPQDLPAYQRAAITAHTNGVVYPFWRDWALAEPCEFLTPEPLHHWHKMFWDHNAKWAIQAVRASHINFRFSIHQPTVGYRHFQEGISSLRQVTGRTHRDIQRYLIPIISGAISAKFVTALRALLDFRYSGQAQRFSQTSSLRVQTALKEFHESKSVILELKARVNPKGKLIDHWEIPKLEFMQSVEPSIRASGPIMQWTADITEHAHITLVKDPARSGNNHDFEIQIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXE1</accession>
    <name>A0ABQ8UXE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_860172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000143">
        <property type="protein sequence ID" value="KAJ4464273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17788" checksum="CC319464BD913A3C" modified="2025-10-08" version="1">MYLEGLKPAPKPVHVVVKLADWERDSEAPEGSQTPYGKSLCYEAKIYHHLVGSNIGPHFYGVFNNSGSIALVLEYKGKRLPDFGSLTDDRKQMLFNQACNLHSLGVKHKYLAPRNVLVNKEGDLTIVDFHRSKLGHKCKGSRRCSELKDFAEHLQIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXZ1</accession>
    <name>A0ABQ8UXZ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_859228</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFB7 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000133">
        <property type="protein sequence ID" value="KAJ4464847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008698">
        <property type="entry name" value="NDUB7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05676">
        <property type="entry name" value="NDUF_B7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4464847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="76" mass="9145" checksum="F0FC1567044E1D98" modified="2025-10-08" version="1">MSPTTLATPEEMKAARLPLGWRDQCSALLIPLNICRRDKNFLPWECEHEKHAYEKCQYDDYMRRMSELSRRKREEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZE1</accession>
    <name>A0ABQ8UZE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="2 17">1.3.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">tRNA-dihydrouridine synthase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C8R41DRAFT_65848</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the dus family. Dus3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="2 17"/>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25585">
        <property type="entry name" value="zf-CCCH_DUS3L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 17" id="KW-0288">FMN</keyword>
    <keyword evidence="16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 17" id="KW-0520">NAD</keyword>
    <keyword evidence="9 17" id="KW-0521">NADP</keyword>
    <keyword evidence="10 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="16 17" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 16 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="20">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="20">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="17"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="260"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="216"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU291113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ4466962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="674" mass="74420" checksum="37A0005D94C7C331" modified="2025-10-08" version="1">MSVFPDGTAPVKAEYLISVDPLPVPDDDAAEGGQGSRSRNGRDTTEANDGGGRNNKKRSKEEKKARQGQNKNRRFAKVRDEQDICFKVAAGTLCEFGADCKYNHDLQAYLAAKPPDLRMPTVDGLLDAGVEDAADSQPALCPIFEEFGECKYGFKCRYLSAHIRKSSSENGGTESLSLVVDEEKKARAAISAKEVNYIGGETQKLLRTKKYPFPVTDAYLLELQEADKREQEIEKERKRVKEEEREKAEAGDDTVVVAEPEQSRDSAAKVQERTAMDVTSAPQADLDTPDVPMRFSEKNRLDWKGKTYLAPLTTVGNLPFRRLCVSYGVDITCGEMGLSTSFLSGSKEEWSLVRRHPSERTFGVQIAGNKPNTLVPTAEVLARECGSHGGIDFVDVNCGCPIDLVFKTGSGSALLDAPGKLGKALIGMNKALGSIPVTLKLRTGVKDGRNTAEKLMTRAVGGGGESGWGVGCITLHGRTRQQRYTKLADWEYIRQCVDAVRAREADEDLPPIPIFGNGDCFSSHDYHSAVERYHVDGVMVGRGALIKPWIFTEIKERREWDISSRERLEGIRKLAEFGLSHFGSDTSGINTTRRYLCEALSFQYRYVPIGLLEVLPAKINDRAPRFRGRDELENLLASPNSADWVKLSEMFLGPAPEAFVFVPKHKSNAYESQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V029</accession>
    <name>A0ABQ8V029_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetylornithine aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_898386</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000118">
        <property type="protein sequence ID" value="KAJ4466059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4466059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="454" mass="49090" checksum="3C03F6C70FD6FAD5" modified="2025-10-08" version="1">MSSSILPPSTLNDFGKKHVTKGLARISDGIMVKGKGSYVEYLDGKKMLDFTCGIGVTNLGHSHPKVSRAAADQCMNIVHAQCSIAFHEPYLRLIERLLPVMPHPSLDSFFFWNSGSEAVEGAIKMARALTGRQNIVTMQGAYHGRTFGAMAVTKSKTVYSDSVAPLMPGVFSIPYPFWHQHRLPPSIPPSILTEQCLYQLHLLLSQQTSPKDTAAIIIEPVLGEGGYVPAPKEFLAGLRAVCDQHGILLIVDEVQSGFGRTGKWFFIEESGVKPDILLMAKGLANGFPLSGIVSRKELTDKLAPGSMGGTYAGNAVSCAAACAVADAFHEENIMANVQARSQELFASLNALRDDQTLAQYILDVRGRGLMVAMEFASSEGPGAAFDPATPKGLTVKKGIASRVTKKCIEKGMLLLTTSVYEVVRFIPPLNISQEDMKKGCDIFAESLREVVREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V059</accession>
    <name>A0ABQ8V059_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_912550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000132">
        <property type="protein sequence ID" value="KAJ4464950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026960">
        <property type="entry name" value="RVT-Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13966">
        <property type="entry name" value="zf-RVT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="364" mass="41414" checksum="A127388EA8A7A221" modified="2025-10-08" version="1">MTIETDSKYVLGLLKNAHELEDTGFINTSNAKLVRSTIASLRLRPTQTLLKWVKGHSGHERNEGADTMAKEAVGKVKASYINLCPPHTLHVTGAKISAMTQALAYKVIMTQKSSDADMYRRRTEINIMRVQNCVEDMFGYIPTPETFWKSIRHKDLELKLQIFLWKVTHDAYWTGTRWANLPKPELQERAICSVCEEVDDFAHILTKCQSPGQETIWQLAGQLWGKKANNIPWRTPTIGDILGCGLARIKNQQVILTGDCRLWKLLIALSAYLIWTLRCERVIANEGRPFQQIEIQNRWNKSINNQLKMDCQMAHKRYEEKALPRGLVIQTWRGVIKDEKNLPMDWIDTDGVLVGIAGGSDDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0G9</accession>
    <name>A0ABQ8V0G9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_44875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF8">
        <property type="entry name" value="LD22649P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="136"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="468" mass="51358" checksum="1E0B06AB2611C102" modified="2025-10-08" version="1">MQDTVDELHYNPFAAPVDSPPRSLSTSSLQNNSFFPTSTSTLSVTANIHNDGRGSSAGGDNQHTEIRKAQAEDANILDHHPLRSAGLSNSFEDAGVTRPHLTRILDSDRLVDVPSFPNDEEDTGQDKATPDEKVVIVHEVSSNDSLAGVALKYRINLTELRRANHLWTSDSIHLRNVLYIPLEKTSLPPPTTLSFASSSDEPTSFYSHESPLPEDRQSPTATPISSSAIRRIPASELSFFPPPSRTSALSNSLSPSQPRPSNSRIIHIRHATTPAPSLNTILTALPIAASTRDTIIARLSFDSPSSSYNDQEREAYLNGHEGHELADVQARREPSRRSLEEDQQGYLDGVTTKLLKKNSQSTFTNDPVSKQPDISAINPDWKARSERVGPKFNRHGRSFSEEYTGPAPSLPSISSTRIRNVQLEPSPVMQIPIKNNENSSQLCSMLCSTGTKKADLALLESDPKFDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1H6</accession>
    <name>A0ABQ8V1H6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_782430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000135">
        <property type="protein sequence ID" value="KAJ4464706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="95" mass="10620" checksum="AFF5D16B310CF2B0" modified="2025-10-08" version="1">MLAKGYGPLAPCVTFLENLSDLPNLTSRHLLVNEATKHFLQKELPHLTEPSFQDIHPSLGNLDHLQVYIDRACDSVYPHGTGWSGSYISTVLLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1K1</accession>
    <name>A0ABQ8V1K1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_854690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="101" mass="9932" checksum="D23664FEB34352AB" modified="2025-10-08" version="1">MKRQDSSTSLITITPSPTSTSGVGLPNPTVSASVGGGPVGLGAGNVDTEIGNITIFVGNVNVSVGDVSIKNVTIGNIFVLVQIGQPDLNGAIGNLSSQLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2P1</accession>
    <name>A0ABQ8V2P1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_48416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000105">
        <property type="protein sequence ID" value="KAJ4467780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046025584" evidence="2">
        <location>
            <begin position="22"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4467780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="41432" checksum="C0013DEB46E0F4D7" modified="2025-10-08" version="1">MRSHRTLIPFIALAVTLAANAAPVLHPLGARASDTNILHMRHASPTPDLLEAQSNADVDFNADSLLRSRTVEPRAKKKNKQKKNKQRKQRQQQQKAKAGGGGGQTNTSSDGQGVPVPEGNKEATPNGGKVEAAQAPPKKPQPANEANGNTHAGPSHSGASGVKEKEKEPVSAATTPSSDHEPKPGGLSRVNTGSSISSTSSHSSTSSDGSVYSCSSHGSTPSSDPYEHDHMYGTHCDPVPHQPAEEAGASKEEEDKEKEKEDQEKSKKKGKQKMRNLVGGASAVAGLGLLGAGIYGIDSLAKSSKSAFTSVGSEGESSESSGLESSGSESSGLDGIQFGVCRFQLIIEMLFTNLLISRSPQRGISSYNFTRCFPKGSRGGKDIFVTIAYYDCCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2Q5</accession>
    <name>A0ABQ8V2Q5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_889008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000088">
        <property type="protein sequence ID" value="KAJ4471182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="666"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="682"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4471182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="805" mass="91405" checksum="1FB60991A493BDE5" modified="2025-10-08" version="1">MMLDEDSEPRTERKKPRLPNACRNCRAKKVMCDSAIRPGNICSNCIAFGSECTHGIAKKRGPRIGLPQGRHSVQATVDAILSTRRSFEVPKDPVITKEILVNLANYIKDLEEDIAQLKQGLGTSSTHREPPPSTALQLNEKGEITRSSLVPDNPFQSPDDYSIDDLTRSFKMFGEFDDNCVRHFGSSSSRALVKDALDMKKEYTGDADFVNVKPSFKRLEFWSVHPWQIRKTEDRPPPFEFPPHDLMMSLIDLFFTKIHLLLPILHRPSFLKSVAKGLHHEDRHFGGLVLAICALGARFSDDPRVFEEHTSNERSIGWKWIRQIEPIKGSFTDPPTIHEIQLYTVYVMFVGPTSTPEACWILISIGVRSLQDVGAHRKLPNHVKPSVETESWKRAFWFMYVTDIFASTLLGRPRSMSQNDFDADLPIDCDDEYWEQGDPELAFEQPPGKPSTMSYWTCYLKLANILGLTLHTIHGVRQSDMWSATMGFSKKDWNERIVSEVDSLLNKWIDEIPDHLKWDPDRENIEHFDQSVMLYTTYYWTQILVHRPFIHRPGEDTQSKIPSLAICANAARSCLRVVEVHQQRKSNAFIVPNVMMALFNSVIVLLVNMWRGKHFIGSSPDLNKELADVHRAINTFHLHENRWEQAGRLADILMEVISVSHFPQSSQPRTISLKRPRRENNILPSSLTTSEAVGNEDQYTTGRNGNIGDPPTASIRELGAKFTLPLNSNELESLPICEPFDWSTPQNQWGSTSANQTADNSWAATLPYDASQFGLYSTSSGTFTNFSGESQEVFRSIFVTLTIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3H4</accession>
    <name>A0ABQ8V3H4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_620780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000093">
        <property type="protein sequence ID" value="KAJ4470063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="612" mass="65746" checksum="0083BA948DFF7F31" modified="2025-10-08" version="1">MSFLQPYPGMDACSPSLDQFASFSTNSKSITHRGEHKRDSISLLEAPSCEGLKENVPSSSTTASSTNTDLYFSDCSGEVSALNNFFDPNSLFGGFNTMGEMDISPPPMPDFLASPQAASGTSANTFEIERGASPSTSSESYHTTHDKLWDSAPAVTGGSDIELATSEKDNSVTSNHRTRSPTNYPELFGEYNSSPLAMDLALPLPLLQSSTTSQSGCGLVLDPLLIDPQAAPPVRSGVEGTSPGPDLSPRIDIPSSLSFINTDIDVSPTTFVDLGVNQTGNESPAGQSSSLGNVIFHGNLAFPSRASVEPAHFAPDAPLAISPSSQTGAALFNPGVTQTGYTPVMQSTHYQSMTGTYLNPSGPEMGPSTIAQSIPQPPPDSYHASLLNQDIFGLPKAEPTLNYALINPHPYWHDIALQFGVAPPPPATIIRSRSRDLVVQAGLKWDHDKGPLILPDLGYLPQPEILPPAMKNVMDLYFSHIIRPPPTADQYILWWNAVWISKQFLLKLEQQQQTTPVRTAISSEPQSSRGNPQAGKTRRKPPTSQNDPFPQSITPAHDSSPVQLPAASQPSAEDLAKMEPFSIFITETGRPRGRAARISDERSKKKARPAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3U6</accession>
    <name>A0ABQ8V3U6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_856327</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="6">
        <location>
            <begin position="155"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4466788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="579" mass="64811" checksum="AF9ABB2247D347D2" modified="2025-10-08" version="1">MTSRSSQIPYGADTSRPLKRGKACLTCRRKCDGARPICGPCQRTPKDDPCEYADGPGRSRVRALEETVSRLEARLREYEHPEETPSIVLHDPYQYEGSTGSSDTAERRIALPGTRRLLEWFLNNAVSFGFFLDHLRFSDSVLLPLDFGHQSRPCPGLLSTVYLWGIHLSPQTQHKDLEHTLLMRALRDTASDLSTSNPHPHRFIHTIQAETLLGYYFFRNGNILEAKRHASSAVSLALGCGLNTLRSSHEQQWSSNINLPPPQDAIEEGERINAFWAAFTLYQDIAVTVDPPRSVCGIFDTPGCQVDTPWPLDMDMYKKNILPPRSSMTLHKFLNHNQQSVDENQISSATNVITKASLLLHQASFVAGQYDPNMPTPEAQTLFATFQSVQQLISSLSSQLFPLKFDHETQKLSAFREIHLAHSLVHGSIIRLNEIFSDSNADCRQYCVKSAQAIIHGGGFDVAEFGCVNPIMGTLWTLACQTLVQEIVRLRSLRTGEVHRSWSYLSSRSSEPASISSLTYRQDHLHVGSENKVKEDLHLDNEDSLLASLQRGLSALTFFSTNSALMDKSFLSSPLSNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4B1</accession>
    <name>A0ABQ8V4B1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_600426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000087">
        <property type="protein sequence ID" value="KAJ4471236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4471236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="35090" checksum="E1A34548538779E4" modified="2025-10-08" version="1">MSVLNDADMTNKVDWFFYGFVISTLLIGATTIQAWIYYTTNHDKWPLRTLVTALVTMDFTLTFLNAEVIRFYLITNFGNLEIFATVSPVLKIEILCSFIVVFVINIFFASRVYKLQQAPFVVTLVIVAAALGSIIAGMLLSARLFQAHASSQLMTFFYTTKAKVEMGITLVLAAFSEILALSTISFSLRNSRTGYTQTDTVLKKLFTFFVSRGIILAAAQIVGICVYFVGKNPLIWLTWNFISTKLYDLNTTVSLSEQSDPHSRHSRMTRPSTGLSLIQFSRREEVFYDDQLDSPIPKIALQSPTVSRFNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4C1</accession>
    <name>A0ABQ8V4C1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication factor Cdt1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_897524</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cdt1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000080">
        <property type="protein sequence ID" value="KAJ4473475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1420">
        <property type="entry name" value="DNA replication factor Cdt1, C-terminal WH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032054">
        <property type="entry name" value="Cdt1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038090">
        <property type="entry name" value="Cdt1_C_WH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16679">
        <property type="entry name" value="CDT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Cdt1 C-terminal" evidence="4">
        <location>
            <begin position="362"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="493"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="369"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4473475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="550" mass="60341" checksum="7E1A5F5354A6163C" modified="2025-10-08" version="1">MSDIYSTLSFSPKKKRTAANFDADTLTPKRLRLAPPTPPTTRNRKLPAEPQISLSSHLTRLQSIQTSLQQALSHALASCAASPTSDTGILCNVTNHISLSQYNGLTNNFTVEDLRRLCWLWEWDGKTIQNAVEDDDNPFLDSPSPSKDWKRGSMGFVISPATQFSKVEGKRVPAYGIGIEVEIDLDKDMGAGMAAVARWTSATETRRALFCEKLHTWTKMHAALPDVPMVPLANLPNLSSPLKSSSLTRVFASMSPKSSSSLPKELVPPTPSSPSRTSSKSPTKRDFAMTASFNSIMPTEGTVLFPSTPTSSRAERTPRILNLRTPTSKLSIDDLSSETSTPRGRDPASILQTPTTSRRQALYDRIRQRSLSASPSKSQRNAVIPGSKLTKDQIMKMGQDEMRRRCLLGRLGGVAESVWMLFSSASGSTPTSTPSSRKRRTLPLVEVATAVMKSSPVPISQAEANESLELLITLCPFFLKQLTIGSEDWLEMPSSIPNDTGSPSKRAPPSPGKVESARELMTRSPKRVKREAGGLREVREIVRRELELHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4M0</accession>
    <name>A0ABQ8V4M0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CxC1-like cysteine cluster associated with KDZ transposases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_775390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000079">
        <property type="protein sequence ID" value="KAJ4473921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4473921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="912" mass="104915" checksum="AFD4CDB89D64E6E7" modified="2025-10-08" version="1">MLIECRPPLSTNPLFHRNFHRYRTGQYRQRLDGRTWKHHIRRLNKNWQPLIPALIDAYTTWKYSPPPHIVTYTDPDASPLVDGRDFDINILDIHNLARVAVIPCGEDDEGAVALVRAGYLGCTPQRPSLAISLRTLELFYTIRMFRPSFSIEAFTKVVCHVHSVTYCRGYRSAISDAFDTYIIIRRHLDSRVAHELGQDTQNYRVLNSCPPCNYELKDELPLKFSRMFVLDGNNSLKRMQGAGNRQVADDRVYQDSDYFLPEEYVNQFSNEVPRGHTQTEDEDAEEPGLEQGGDPTDGQTSMSETSPLQKCTSNWKAAAGDAAKKMWDGFHETGISASACRHGFIIWLTDMIRSGELAKHPLAITAKALEVFGENMLIGYDIGCRFSETIAKTSLNEAFQKKKCRTCVNAFHGYSHNALCQQSFHPTHIKGMGLEDLETLERIFSQSNQLAAVTRYMSRYHRKVFIDLFFRQWDSDKYANLGTMLFNNYIQALHILETEAAELVHDLEQFNLTESDLEAMWVDQAGHFKELGKERAEEVNGVAYVELRQQLRDIEAALERSYTAFRIQEPEDFEQLPPLSSYSSGLSETRKTETRRCFLGEKRDNVLWEILQMESQMDVQRRWTPLDSEYKAALKYMTERKYLQALENLHLLVIKRLFEMHKLNMSGTGYKMRTHIAQALQRRAKAIRNAVNEYNKHALMLDPPRDTLDWTKVTHFSFIDQFDILRDTQHNVFHEKWAQPLYRELMNRVHKVSRAREEIHRVNIELRRLHTRIVDEEKLFASTLGHLGGSLMLGPVLEYVTRRREVNKLLISRINATYNLPGFTGTPYPGESINPVHATYPHTPSASEMHEPDTSPPTSPGHNAGSSNVPHSTPDDRQPQFEDDNSEDEGPLEDDDEFVDDMGKVVDFIAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4V7</accession>
    <name>A0ABQ8V4V7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_778115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000096">
        <property type="protein sequence ID" value="KAJ4469345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="17"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4469345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="357" mass="38381" checksum="375EB90F87B22324" modified="2025-10-08" version="1">MTTELQSSNVRSIFLLGATGYVGGQVLVSLAHDFPSFPIRALARNITPPKLTQLRALHSKLEVVEGSLSDHNVIEAEAKNADIVINVAAAGDTDSVNAIIRGLQQRSRSYTPTVPPIYIHMSGTGIMGDNARGELIVPDRLWVDTEFDLENIKTKLLTKACEAIVDAGKNGEIRTMIVFPGLIYGIGPGIQKISLPHRFYLNLAAQAGHSGSFGPGRNIAGLVHLKDVASAVSAVLEGALNGGKVGEKIGEGKEGIYFVLSKYMLSMMEFSNIVGDTLFKQGLISKTGSSPFSASIADKAGPFGYNIFGSSQFCRAERLTKELGWSAEHTETESLYDSLPKEIELAVKEMGLQFPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V544</accession>
    <name>A0ABQ8V544_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000076">
        <property type="protein sequence ID" value="KAJ4474785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="269" mass="30561" checksum="594BC5C4970156A1" modified="2025-10-08" version="1">MSVTLAPNTSLTPNTSLTTSDSIDNQLEKLCQLNFEFLTTPTRKLREKDIVPVGDHPESRRPQFALDGRMSEATWSALIHSLEVIQRADQGRKDDTPVSEESAQKVALPQPPLKLILKYAKSANPLSYPGSRRQIVYTYYGARLLLVRIVQWMSLCQMRAVQLEEEGINSGWNWKAALTEDTIAIPNDLNISDEMFTSPNIETYDPRLPAFNPKLISGQKEEESREMVLHPYASHYACHFPNFDPFSGKELKEIEDCLGKEFCTRNKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V556</accession>
    <name>A0ABQ8V556_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OsmC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_780573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OsmC/Ohr family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019953">
        <property type="entry name" value="OHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03561">
        <property type="entry name" value="organ_hyd_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797">
        <property type="entry name" value="ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797:SF2">
        <property type="entry name" value="ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="OsmC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="17049" checksum="9A0B50E3EAE1D032" modified="2025-10-08" version="1">MSFARTTLKASRAFTSASLRTRSRTLVTLKDHKYTAQAVAQGAGRNGEVTSNGLDLKLALPKEMGGTGQGQNPEQLFAMGYSACLLGAIQAVAKNLGKADMAKNAKVHASVHIGEPEGMPGFGIAVDMKVEGIDEKLLKAGHEFCPYSRLMKNGGVVNVSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V623</accession>
    <name>A0ABQ8V623_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4476179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="267" mass="29861" checksum="A30201746FA1CE56" modified="2025-10-08" version="1">MTPTNCVSVGIHSLSNSPTSYSTYKKTSVLRSKILNEILSELSLNDRLSNDSALEARLSEEIESRLSLIPEFLGDTWPTLGDVDIPLLDQIHKEIEDIASLESELSSTWSSSIDVISRINELHITLQTELLDAISTIPPALNKKRKADNALSAAVIEASLVKLSLMRAQSHQKFYGYVSKTQPDATMIKALSIAQDKLRDEADDLLEEERALDSQIEAYARLMRLVDGSPQTDRAGFAQIVEDYIRVEKETEECRRDLRRLGWTGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6C0</accession>
    <name>A0ABQ8V6C0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_923552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4475843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="33873" checksum="291B64B75C01E793" modified="2025-10-08" version="1">MSEESPQQLVWMITGCSTGFGRRFVPAILRRGDKIIATARNLSTIENLTTEVSEQDLDANNLKILELDLEWTTAKLEGVVKEALDTWGRIDVLVNNGGVGMKSLIEEADARLFARQFQINMFGHVDVTNAVLPSMRARKSGTIVVLGSRSSWRPELPATGPYASSKAAFTAYAETLATELAFFSIRVLIVQPSSFRTENMLTYPYHNDKLIPEYDILREKALAGAGSLHGNQPGDPVKAVELVVDVVRGEGKAKGRKFPRYLPLGSNAGQAIKEKTDMMKSVLEEWGDVIGSELDYETVGVTKMWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6Y2</accession>
    <name>A0ABQ8V6Y2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_557705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07091">
        <property type="entry name" value="ALDH_F1-2_Ald2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4474180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="502" mass="54102" checksum="1D604E16F18A64DE" modified="2025-10-08" version="1">MPAIFSHRFDTPLYTGNVCVQTGLFINGAFVDASSRTTIDIFNPSTGKVITQVSEGTAKDIDLAVAAARNAFNTTWGLKVPGSARGQLLYKLATLMEESLEELAAIEALDNGTAFGVVKGWVVPFSIGLIKYYAGWADKISGQVIETDEGRLTYTRHEPIGVVGQIIPWNAPLLMFAMKIAPALAAGNTVIIKPSELTPLSALRVCSLVQEAGFPPGVLNVVVGYGNTVGSALSSHMSIDKISFTGSTLTGRKIMEAASKSNLKNITLELGGKSPNIIFNDADVDQAVNWACHGIFFAQGQICFAGSRIYVQSGIYDEFLAKFTVRSKAHKIGDPFGVDSYQGPQISSTQTERVMGYIKSGVDQGAKVHLGGQRHGEQDGNFITPTIFTDTRPDMKIVQEEIFGPVSVVIKFEDQEDVIQQANDTIYGLAAAVFTQDISQAFEVGHALKAGTVWVNCYNEVHAAVPFGGFKQSGIGREYGSYALEHYVNVKAMHININHKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V866</accession>
    <name>A0ABQ8V866_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_711055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000081">
        <property type="protein sequence ID" value="KAJ4473214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4473214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="9020" checksum="782168FECF703EC8" modified="2025-10-08" version="1" fragment="single">GPAIPRRDRKEVWPRYCRLMLMFFKPWRTGTDLRNEGQGWEEAFEMFLVSCLVRIKEVMENMQILHECRDSRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8L2</accession>
    <name>A0ABQ8V8L2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_848053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000077">
        <property type="protein sequence ID" value="KAJ4474573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046617292" evidence="1">
        <location>
            <begin position="19"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4474573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="107" mass="12173" checksum="03EA570B23F8BB8E" modified="2025-10-08" version="1">MALGVALCSVLWCIHVHLFFHTHTHTLSLFYTNPTPPPSPTPFSNSFPYSHSHSFSNSFSHSHSFSHSFSFSNPNSYTHLKITLSNNFLTPIHVEQGFLLTWQGFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8M5</accession>
    <name>A0ABQ8V8M5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_869930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4475442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="491" mass="55547" checksum="2EA898D2297D742C" modified="2025-10-08" version="1">MSSLKNQDQNSINSTYSAEAKYKRSWGSYIWDTWDKSPEERRFLTKLDSYQQNITNAYVSGMQEDLHLVGNDLNYITTAWTCGYVIGQIPSNLLITRIRPSLWIPAMEVLWSVLTVLLSTSKNFTHLVVIRFFVGLAESTFYPAMQYVIGSWYKTDELGKRACIFHVASAIGPMFSGFLQTAAYNGLNEVHGLAGWKWLFIIDGIITIPIALLGFLVMPDLPNNTRPSKWLYTEAQLEIANKRMAEINRKPPSKFTKAKILGFFTTWHIYTLVPLYILFNNGGGPASSMIFWLKSFNTPTKTVYTVGQINIYPLGQNVVQVHCLGPGSQMQSTWSMIICILLAVTPLYTHIARRWALYYMTTVPAGMSGLILAWANELTGADSEKRSFVVASCNMWAYVMQAWLPMWNNPVFFAFLTYLLQRRDARRQRSLEKSQSTPDNGIRVEGLPYEGTELLIDVVAGKIEGFFGLLGCKAQKPDARMSQDKDATYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V910</accession>
    <name>A0ABQ8V910_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_904263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000059">
        <property type="protein sequence ID" value="KAJ4481304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045167035" evidence="1">
        <location>
            <begin position="24"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="253" mass="28881" checksum="7511E637049F8DC3" modified="2025-10-08" version="1" fragment="single">MRLPLPAMICMFILCLFSEWTCAMPLALDTPRIDEIVHAENAAPKFSPTPIPSVAVRDGNSEKLQSFRQWQTEPSIHKRKSSLMSRLEVRFLTQEEIMEDTKLPEGIRKFAQEEFIQYHGNVTSTTTTTAAAKIQEQAKSIIRSHLLWNLPYGENGMLYFGEKKHTRTLIFPDDNSKLQYPFSSIPDSGVAYEIHDRREESLGPCKPRCHGAAWIIKAWRRVLGNKRVGWGAFLDPPSTFAYEQLAAVRRTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V967</accession>
    <name>A0ABQ8V967_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000073">
        <property type="protein sequence ID" value="KAJ4475826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="71"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="393" mass="44960" checksum="969C74FA1EA5A8B8" modified="2025-10-08" version="1">MVSVIFWDVQGNRIEDTLPDEEQVDILHSVTEILPDAPVILGELRKVAQTDISKLHQLGQNHFFVFDATMTDGAHYIVRVARFSEPTELSYLRDKVQRECEILKWMGSLDSLPVPKPILCDATSPSPPFMITNKCEGIQVIYGFGTLSEDAKMRNLRSFARFAIAMFQAKCPQQIGSIMRFSSNSESPRDSGSTKVEIGPVVAYRKTETPSQCFSSAQEYIRWLIACKQNRANSVANVKPILRRAEAIFAQETQRQDEEQLRCIPWHGDAVSHNILIDNSGEITGVIDWEFHMILPAYLAVDYPSWITYDGLQDPNFFPTTGQFSPFWPTSRQEATSLRQMYDEHLEIVKKLDHTYYLSLKKGEIARLIMQWLIADEDRELFVRTTTYEDTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBG4</accession>
    <name>A0ABQ8VBG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_910904</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000057">
        <property type="protein sequence ID" value="KAJ4482664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4482664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="468" mass="50889" checksum="7C4282512246265C" modified="2025-10-08" version="1">MMLSSTVPEAASRLLSFVNASPTPFHAVQTTVQRLEKVGFSKLKESDGWDKVVKPGGKYFFTRNQSTIVAFTTPQNWKQGAGLSIVATHIDSPNLRIRPISKRTKAGYLQVGIETYGGGIWHSWLDRDLSVAGRVITSNGSGQFKSRLIKVDRPILRIPSLAIHLDRGVNDSLKFNQETEFVPILGLISEQLNATSESPKLSTRDVQASSIANNHHSALLSLLASELSIAPDDIFDFELQLYDNQPSQLGGIANEFVFSPRMDNQFSSFCAVDALIGSLSSNSLLEGNVNCIALFNHEEVGSVSSTGAESNLIPSVLSRLSPTPDLLAQSIASSFLVSCDMGHAIHPNYTNKHEENHQPRINGGVMIKTNAKQKYTSDAIGSFLVKKLVEKKGGKVQEYEARNDMPCGSTVGPSLSTMGLRVVDVGCPMLSMHSIRETAGTSDVQSCIDLFQSLFENFAQLDAELVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VBJ5</accession>
    <name>A0ABQ8VBJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_896990</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000063">
        <property type="protein sequence ID" value="KAJ4479499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16180">
        <property type="entry name" value="EFh_PEF_Group_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4479499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="215" mass="24357" checksum="E0074A1BCCDF0874" modified="2025-10-08" version="1">MYSQSSGYGVPHQHQHQHHGSIHSTHSSRYSRPEGYGYQAAPPPGTDPTLWAYFTGVDTDRSGSITANELQQALVNEFDLDTVKMLMSTFDVDRSGTINYNEFAGLWKYIQDWQNVFRHFDRDHSGTIEGYELSEALRSFGYNLSPDLLRMIEQKYASAPISGYGPPPGITFDRFVRACVVVKTLTESFQRADVNRTGYVQFSYEQFMSIVLSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCA4</accession>
    <name>A0ABQ8VCA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_768350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000049">
        <property type="protein sequence ID" value="KAJ4486901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4486901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23704" checksum="5906C33B0E4D9C91" modified="2025-10-08" version="1">MRSVDAQLERLYQQARVDVAHQNHRRGQYPTLPAGCGFGGGRTEPGNYANTPHNAALIEEILANREFQLVASFIDAGVQTTFPKLHTFLTNLLDKILADNPHIKKMFNGCCYGACHFNLHNACTDNHEDYFNILFAMCCAFCVGNFDHTRGGHIIAWNLGVVTEFPPGAAVYLPSAWVTHANVPIAPHERRSSIAFFTSSGLARWYQNGYMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCL0</accession>
    <name>A0ABQ8VCL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_447504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000053">
        <property type="protein sequence ID" value="KAJ4484540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047520521" evidence="1">
        <location>
            <begin position="32"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4484540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="147" mass="15953" checksum="781CDD777EE071A0" modified="2025-10-08" version="1">MTQLVSAHAITKLYSFLFVVLQLFLAKTVRTIPIGSETVHGGSSSDLTLDNHNFVTLDVSNTAGLSSSNRARAEGPTIIQAHIVVNTSLETPDDVLLSIHDATVSFQSVAYEEPRTTSKLRELAERWVKKWVGPARNPGGPPITNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCS5</accession>
    <name>A0ABQ8VCS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_720093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000056">
        <property type="protein sequence ID" value="KAJ4483121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4483121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="86" mass="10081" checksum="7BE70A52EF972EF1" modified="2025-10-08" version="1" fragment="single">IKGCLYHYHKTVNRMGRIGDAVPQNTKSEFQKLCRSLPEITDVKHFDDIVSTIRKRWPCVSRWLSWWLMSEHAGMLFPCKLTMAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDC3</accession>
    <name>A0ABQ8VDC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_767163</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04515">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.200.10">
        <property type="entry name" value="MHCK/EF2 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004166">
        <property type="entry name" value="a-kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051852">
        <property type="entry name" value="Alpha-type_PK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992:SF2">
        <property type="entry name" value="EUKARYOTIC ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992">
        <property type="entry name" value="EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02816">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51158">
        <property type="entry name" value="ALPHA_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-type protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="222" mass="24310" checksum="5D7256D46341C3AD" modified="2025-10-08" version="1" fragment="single">ALFMHKPVGSSNDLNKAGLHAELDLLVQGNGFAQSFKLRASAVGLKLPDIKYNAENAFVGTITTPLPASPLPVDDAVVEFDEDRSLLFDTFLVVPLLQTRGIFTERKFSGNMQTGDNTDYVGEVVDAFAHHFLEETSCMFMLADIQGVVGPDCSITLFDPQAHSTAGDSGKWDQGSNVIKKFCDEHHCNRVCRQLKLKSLKDQYHDSSCSPRNGSLAFILGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDD4</accession>
    <name>A0ABQ8VDD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_920810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4489136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="495" mass="55100" checksum="4283EA447E6C56EF" modified="2025-10-08" version="1">MSFFSSARPPLPPGPKGLPLIGNVLDMPSESEWLTFAEWGRQYGGLCSVTLMGQPMIIVNSGEIMEQLDKRGSLHSDRPRLQMAGELVGYSKTLVLVPYGQRLRNYRRHVSRMIGSPGTLSQFHPMIEAETHMFLKRTAANPDSDLLSHNLRKTSGSIILKLSYGIEVQEENDPFVSLIERANDNFSLATKPGAFLVDVFPSLRHIPPGFPGAKFHQLAAKWAKDFNDMIEVPFNFTKELMSKGIAPVSFVSASLEHEDKLSENEIFEIKHTAASIYAEGPQLAGADTTVSDQYSVFLAMVRHPEVLHKAQAEIDSIVGNERLPTFSDREHLPYLNAVLTESLRWNSVAPTGVPHRSMEDDIIGGYFIPKGSIIITNLWNMLNDPEVYPDPFKFDPERHISLPGKPAQKDPRHACFGFGRRVCVGMHLAEASLWIYIAMILAVFDITPALDEQGNPIIPEHENTTGTISHPKPFKCIVKPRSEKALSLITADIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE42</accession>
    <name>A0ABQ8VE42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone acetyltransferase type B subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_835075</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="6">
        <location>
            <begin position="23"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="234"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="278"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="322"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4489188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="464" mass="51508" checksum="A64DFD4C38CAB95E" modified="2025-10-08" version="1">MKPQVEEVEDDYAAEEENKLINEEYKVWKKNAPYLYDLVITHALDWPSLTCQWFPDKETPPGKNYTVHRLLLGTHTSGQAQDYLQIATVSIPNRDNTPHSDKLDRENYDGERGELGGHTIPPSPRIQITQKIAHPGEVNRARYMPQNIELLATKAVSGEVLVFDRTKHPSEPDQGGGSKPNIRLVGQSKEGYGLAWNPNKAGHILGASEDMTVCHWDCQAYSKENSTIQPTNTFIGHTSVVGDVDWHSKKDYFFASVGDDKMLMLWDTRSPGGPVTKVQAHDREILAVAFSPASEDLLVTGSADKTAILHDLRSPNRKLHSFESHTDEVLHLAWSPHNPTIFASASSDRRINIWDLSLIGQEQTPDDQEDGPPELLFIHGGHTARPTDFCWAPEEMENWTAASASEDNVVMVWQPTMRVWAGEQVKIDVKELEDDAMEGVEATNEPGASGSKSNSSVSASGADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEP2</accession>
    <name>A0ABQ8VEP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_833907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="81"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4491738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="467" mass="50581" checksum="BBE6D474C7F22FEE" modified="2025-10-08" version="1">MVNEHTRTRHPASLIDISAHNPQLVRLMGSRVNMDMIDYIARQAANVICIEGESPIIASSVASMPSPNCAYDSVASLPLREFIGHLVRHAHVQVPTLLATLIYLERLRSKLPTLTKGTTPCTRHRVFLATLVVAAKYLNDSTLKNKHWAQYALFFTIEEITLMETQLLGFLDYDLRFDEEEACRMFAPFMATPAQRASTRALAVDRVVKAGRARVQAQQIPDSSVEAIPPHLPSQSSSTSSGLASTVRTLAKRISNTHISSSRSQSTTSTASSPMYTSLSTTSTLSSSSSDVGSLIEDFGSSSGSSSGWNTSDSESDLEEYAEPQVYSNSSMSLYPRDEQVPERLIKSSSIVRSIPSYAQKSQQLRSRKPSDASSICTVTQSPLISAAHSRRCSNKRSVSISVAGTDHVKDSGISSSATMPIISRGTSGNFLARMWGAAKGQAFRRLVLVHSRSGLSRGASSSGVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEX7</accession>
    <name>A0ABQ8VEX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_833360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF131">
        <property type="entry name" value="GTPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="32"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="748"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="628"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="702"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4491837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="843" mass="93996" checksum="F9C2E6BAC339DC65" modified="2025-10-08" version="1">MASNLSSTVYASRRKELLALVNQLRAVGAQNELDLPRITVIGNQSAGKSSVVEAISGITVPRDAGTCTRCPMECRLFSSSNAWACRISIRIEFDDDGNRLREVAENIFIGNITDKSQVEFALRRAQFAVLNPEISWDKILKSPIEELKKLVNAKSLPFSQNVVCVDLEGPDLTDLSFIDLPGLIQNAQPEVVQLVEDMVVSHIKGNCIILVAVPMTDDIENQKALRLASQEDPDGRRTIGVLTKPDMLTTGSTKVARLWLDVLEDRRHLLRHGYYCTRQPDDDERSASIEQKKAREIEEKFFKTTTPWCQSVNPTRFGTQNLVSTLSRLLVQVIDEHLPQIREDASKQLSECRKELTRIPSPISDEPATYMLAIVTSFCSDFRTLVRGSADSAELIRLHRRSYGTFKNTIRKTAPSFVPFEASQTVSDFYNCLDDEEDDPVARVSAIGKSTMNLTEVRNHINLSLTRELPNNVPYEAKASLMARFQESWPKAVDDCFRSVESDTLAVLTKMIEKHFGRFSLLQSQMKNLVKALLDEHKAHCNIMLDYVLEAEHVPFTQNGHYYESCKQGWLTKYRAVRSGKVGEEELDPQVKRHRVAAPGFESSTFLNTNSASKGGPATSNLFSFTGLGNRHAPEKSPSPIPSASSMFGLPPSTPLTSGNGPFASRPIQFPTATTEPKPAPSQQAFTVAQDSDSETNRATERMNSNSPDKQTVQEAIALLVKAGLPVASLDPMDLLGKLIPPDEYETELGVMAEVRGYFQVAYKRMIDNVPNYIDLLFVRKLGKSLQPHLISKLGMGTPSANERCGSLLGEDPMLVLRREELLARRKRLESVEKELDAYSLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF29</accession>
    <name>A0ABQ8VF29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_833468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="342"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="372"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="628"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="727"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="628"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="681"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="733"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="784"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4491873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="802" mass="85061" checksum="36350C5AB17F3DA5" modified="2025-10-08" version="1">MEQSPPLAELEEDWDENDEGEYDEEEDGDDDIDAQAEEMARKLNEQLWEDMRRAATTESVSTTPMEIDPASAIHSNTSDPASTVAPGSSQKEEAVLSTIKAIMALLNHDSVAHNILASTALPSTPFGSVLDALIQTLTTGKVTKPTAIILSQTLVGLAGSEALFGSLKGRDAAQAKKEILGKRKREEEPVTIPPPQLPSKYDIVSEAVQVVTHALHTSSSINPALITSIQESLRNIFLFCVSAAARPVESGASASTASLQEISGLIQVLGVLSGIQFGLNTAHGTGQSADINAMVHPCMVPSCNKTFMQLTNLRAHENTHHFNQSQPNSASSNVTATYDRPFPCTFPSCSASFLRNHDLKRHIKVAHEHKSFECGGCGKKFSRRDAIKRHKDASVAKSQQPSLLGRPVILCYEAEVIEIEGGVEDQDGLDDDETLPDIKRARTVAEEGGEEEEGELSEETISTTQAVIMQLHPLLRAVVAKASGTPLPLIPFPTQTVDPLSPPPPQTSSSSSEQISNPVATAVDNLTSQLESKISDDSSSSSQQVKRTPELEPGVRFPTIVPMTTKISSPSCTEDSNIIPVTPPASHTNGVPIVTGYSGLSAQQSSSQPSQPPTLASIIAHAQSQNPIPTTVTDTVGSNSAITGESNKISPSSTTPSTANIPMEPSNVEPNQDANHIPPWSFSSQLASTLAQSSSLHPQPQPQSQIHGISNYQTQLLEQAIANAAHAAQAEANLEEDGDENGDGDANGKDRAELAGASQEETAVTTSANRDVVGDRQVGGGVDSDADADGEVDMDLQNENIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFF9</accession>
    <name>A0ABQ8VFF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_919930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="172" mass="19399" checksum="81C4862B100CE0F0" modified="2025-10-08" version="1">MSLEVRVVSVDTGRLRLLEEQALLKRKEVVQLRGVVQRLRSRYELELNMDRSKTDFHDATALVHRLRTEILTSLGRDTVDDQCLKVITTNEAEYFWSFVDGVLSTSERKDVASSSASPSDPPEADISASELTVLLIEQSLKLDELAGNLHTGVAERHLRNQCKQLCHLARSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFM4</accession>
    <name>A0ABQ8VFM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="861"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="973"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1035" mass="118657" checksum="0BC5A07BA652B1EF" modified="2025-10-08" version="1">MLVEQQLSSPYHWQTVVSLIIPDTQRHLISDQPTNISTMEQPTNTMHAVLQCEWAQSLNSHDKEINRQVMIATIKAEMYSYLQKYRSGMIDLATNAITTEPWKPNVLVSERTIKAITQLNIPRACAPYSHLPDMLSHRLGRFQDDAKLKQRMHELFGSETHKIFVNTSGAGKTRLVLEHLCSNWGLYLTCHDDSRIGSKDLSIAISNIKASRLFKKSLPPSIQLLVSTQDRPEHAKQSAGRALRDRMEDFESTPEGHTFGRALETNNGLVACELFATLLARLHILHQFLATLVEIGEDITQPMHIQNWLRIQLHPDLLLPQNESGDMFAQFRNHIAKMLGHFQDLKDSEEILSELLQDILTKIRSILHFNLIIVLDECQFAARELRNSFRSDDWITKRPLLRQIAKCLNDIFLESGVHGSRATFIFTGTGLSKVDITDALSSIVAKAPPCDDVNDTGAFDDIDTLRNYIEGYLPQHVLQSDQFPRLLERIFRWLRGRFTAEYISVVLQNGYKHLDKLLNAYIYNLTGFEPTDYSGEEVISRLITFPTRAFIFETVSDTMKERIKSLCYDYLLRSRLEGWLGDDEDDYIAYGFARVKFSGELKRIRIDEPLVLMACAMWLNGSPGVMGAHSLYKYVANRIQDHNPSTGRNGFEEFICFYLQRVFQTPRRLGQVFDFLDKKSALAQKRATLVTLHIDKVGTKRALGLGIESLDESVSLTDWVKLKSHTAFCFPMNEMGPDIMCFLKLQGDKENPEDFTYICLAVQCKFYQVDGELEPSTLKDAIATVTPKKFFAPRHLVAQVKDEKKAEGREEKRRGLRRCILRALKRLPHRDPLAGKYGVVRIICGFPVKVNLETAFYKHKKQGKTPKYTQDPDEEDHHPLGQLNADLLSTETAHLHPTNLLKVIKGRARKEKKKGKSFWDTFDPAILWSDSEDSEDELPTKTGRRKIADAAEPIEFGSQARMVIEMLDSDYSRSRGLDLPSRPKRKREEMDLDELDIDRSEDEGYKENYRKIEDDSNANYEDDYEDDDDNDYNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFQ2</accession>
    <name>A0ABQ8VFQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_832851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="146" mass="16753" checksum="81EE002E2F931718" modified="2025-10-08" version="1" fragment="single">MDPDLEDVIEAIRLMESDNKIMPSVKGEWKLPIWAPTREDTDPDIMDHVRKLGIPLGNREEIPLVILHKLGSFQHDPILKKRLDTIFSPNHHTFVYMCRPPFYFVHHPVFLSIRLALGKLNSFSKAFASIGDSILQLGTIKVDKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGB5</accession>
    <name>A0ABQ8VGB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_339863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="93" mass="10538" checksum="7BD3C9235CE60290" modified="2025-10-08" version="1">MPNNVAIFPKLIASCTSLLYPCLLSIVLISLLFVRVYIALVTHFGLVQSTEHIFLFSSRSTCYHQVFIPRIPLAYIAIHCTVCMVNQDLPKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGS5</accession>
    <name>A0ABQ8VGS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_317180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="230" mass="24733" checksum="20367BAAEDF9365F" modified="2025-10-08" version="1">MQAPRQGSTFNTPFPSSQHIPSYSESSTVSSSVAFPSRGEGYVLPARSRTGSIAGGEVTRRLLRTLSTVSIYESGEGLAGGLADLAPIGRYIVDRQTTEADAPASEMPREFGINEADEDAWDEKVRKRERKEGKFFVGDGQKPTSSSQNPTPNLTASRSHSQSALDTSPEPSRSGGNELQAPAHSPKEKKAPVVKKLSVQSLEQALAEAVTDEQPKSGEASTSRRRFLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGU1</accession>
    <name>A0ABQ8VGU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="285" mass="32084" checksum="B9C1A3E087D76138" modified="2025-10-08" version="1">MTRDIRHIYLFQVDLTAITTPMLDDTDTPTDTTSITSAVPQLETSSHLTCCCQQDDCSNFKAWKAIILRLENNFILSTEAGQALLQRYDALRLLHQKLDLALINNEAAEASAFTLHRELDEAWATITRLSANHVDITTLGTLLSRLNGELDDMQQERDIALIKVSVNESKLKLSMDKASELHSENRRLRKELRQKDQLHMDSNESLLQGAKSKIQKLALNATLGSTATSTLENAELTKALETVYGHNKNLKRHNNELQALLADAQDEIFTMREEVEVHLANPPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHK7</accession>
    <name>A0ABQ8VHK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Clathrin adaptor mu subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_766106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="167"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="427" mass="49182" checksum="13D9BD7AE48C588A" modified="2025-10-08" version="1">MASLIAILDLKGKPLIQRSYRDDVPPSYVERFLPIILEIEEEGQQVTPCFSREGVNYMHIRHSNLYLLALSRRNSNAAEIIIFLHRLSQVLVEYFKELEEESIRDNFVIIYELMDEMMDFGYPQTTESKILQEYITQESHKLEIQVRPPIAVTNAVSWRSEGIKYRKNEVFLDVVESVNLLVNTAGTVIRSEILGAVKMKCYLSGMPELRLGLNDKVMFESTGKTARGKSIEMEDVKFHQCVRLARFENDRTISFIPPDGEFELMSYRISTPVKPLIWVEAAIESHRGSRVEYMVKVVAQFKRRSTANNVEIYVPVPDDADSPKFRASTGSVQYAPDKSAFVWKIKQLAGGKEFLMRAHFGLPSVKNENDPPPRAPITVRFEIPYFTVSGIQVRYLKIVEKSGYQALPWVRYITQNGDDYRHWLPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHM9</accession>
    <name>A0ABQ8VHM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytoplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_883544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GET4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875:SF0">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="35962" checksum="B09CB6BF2DBBF1E6" modified="2025-10-08" version="1">MSSSRALNAILPQIEKSPYEAHQKARTFASRYVKSSQYDVAIDVLFQSSRELLKTGQPGSGIDLAGFLLEVYDTKGENVTEESRGRLTQLIALTGSEGAWRKTLIDKSLAWSAKHGPCPAGDQALHHYIGELLYKEGSFDTAERHFLASGSRDSARLLAEMFIQWATPTNTFGLFALRGTIPYLQNGNILAARTFIKHYVSASVLPRSTVGSTLPVGTSGDEIIVAQDPFVNFAQLAVVTCQRANGERNKVMRESWVRLCGTYQSRGGILAQPEVRRALQDIATLYFAIPPPRSQAGNPLGDMMSSLFGGAPSAQPVRRVLTPATAATGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHN9</accession>
    <name>A0ABQ8VHN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000036">
        <property type="protein sequence ID" value="KAJ4493268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="57925" checksum="9CA7836592F3BB5A" modified="2025-10-08" version="1">MVVWCKEQLFAGNGDGEIMIFHPVAHWFGKQTEQIVSEFYSPIYCLELNRSGDQLLVCSGSRTTLLGERKSGHWKLVYHFDSPSCFEETAELGEPDGFDEPQVLATSTHFLHEKESVVIGYLHHGLWKHQIKTGTAVLVWGPDEKIGFTALLPDGTALAISNVRSGIDWLRVYTGSTRWKKISTTLEIQDLSANIPLPVQFIDKGKYILMGTSKGYAVIFHAKHGKRVISLDHGSDKTRVTALAYVHPKNCPQLLATGDGNCGPNTKIKVWIEDTEEKRETASPSGLNGQESSLRVYVRSIVGAVYNVSAVIGVMAIILLLLPSAWKEFDIPIAKTLLSKHVIQILKPLPVSTLATLDTSGPLSTSSPTASTANSADPTSIVLTLVPVTSVSSDPPSLTTRYSDGQGIWDRIFGAARSGTACDCYLEFDLEGWGGHISERALGSRYCPQFDGFKIPSHISHYCPYISKLTRAWITELQDPGLVYKIPTIATYSSSHRPQPFEVDVELLLELARAGGAAVLFKWLGLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ47</accession>
    <name>A0ABQ8VJ47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glucanase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_918474</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046183377" description="Glucanase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="480"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4496417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="516" mass="53453" checksum="4F8C4942953790E3" modified="2025-10-08" version="1">MFRTAALLSFAYLAVVYGQQAGTSTAEVHPPLTWEQCTSGGSCTTQSSSVVLDSNWRWTHVVGGYTNCYTGNEWNATVCPDGTTCAANCALDGADYEGTYGITTSGNALTLKFVTASTQTNVGSRVYLMAPGSETEYQMFNPLNQEFTFDVDVSALPCGLNGALYFSEMDADGGLSEYPTNKAGAKYGTGYCDSQCPRDIKFIEGKANVEGWTPSSTSPNAGTGGTGICCNEMDIWEANSISEALTPHPCTAQGGTACTGDSCSSPNSTAGICDQAGCDFNSFRMGDTSFYGPGLTVDTTSKITVVTQFITSDNTTTGDLTAIRRIYVQNGQVIQNSMSNIAGVTATNEITTDFCDQQKTAFGDTNTFSEKGGLTGMGAAFSRGMVLVLSIWDDDAAEMLWLDSTYPVGKTGPGAARGTCATTSGQPDQVETQSPNAQVVFSNIKFGAIGSTFSSTGTGTGTGTGTGTGTGTTTSSAPAATQTKYGQCGGQGWTGATVCASGSTCTSSGPYYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ56</accession>
    <name>A0ABQ8VJ56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_826406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000028">
        <property type="protein sequence ID" value="KAJ4496427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="239" mass="26985" checksum="413E64D5826EC536" modified="2025-10-08" version="1">MSLLSDIIQDAVKDVYASKYASLAASVIIVYDHLITLDNEFDLIWKSSWSIGKGLFIINRYYSLASVIANNYALFGTALTNSGCLRYYHWQGWTGLIACMIAETILQMRLYALYFLNKRILYLMVGSFILTSASAATIMSIAINQFQAETHLLPGLPCVALHVPSYFYSFWIPILAFETLLCILALIRGFRAHTESGYPVRSDSGKRLVSLLIRDSVCYYVVMFATYLTCLLVWVVNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJ58</accession>
    <name>A0ABQ8VJ58_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_762424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4495661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13751" checksum="56BACCC53FEA5502" modified="2025-10-08" version="1">MVSLLDDDGAISESFENCLKHIFAKYCIPESMSPFSGELPLNAYLDSAGLDSWASDTNGEPFSEDTKEEILQFMDVTDEGNLTFKGFLQVYQLQTENDEEETWRDLSKHGYDRSLMFIGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJB6</accession>
    <name>A0ABQ8VJB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance of mitochondria protein 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_895742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045318451" description="Altered inheritance of mitochondria protein 5, mitochondrial" evidence="1">
        <location>
            <begin position="25"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="14001" checksum="C90F09C3F7C86BD7" modified="2025-10-08" version="1">MNTLSAFGIATLLVSVGAVAGVWAIKTTMDVQDTQEFARKMRRIVLTRMPMLSARIHRVLDDEGDDNPIDSTDWNWEDAERRLRDAYEKDGIVAWAEATLKEFRAEEHSERLKRKELEDAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJJ5</accession>
    <name>A0ABQ8VJJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-dependent phosphotriesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_828606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000031">
        <property type="protein sequence ID" value="KAJ4495308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="408" mass="45006" checksum="CB2A6CE4A70B0A0F" modified="2025-10-08" version="1">MLNLLIGAIVGILALLYAYRTTILPERIIHDRHGQIAIVNLLEFNVIGTDGHFRDVLRDRHFNPTNHTVPFFQVFEDEFLDVVGPNPSLNVISSDPSFAFAHEAPVWVPDTDEIFFCSNAGGYLGRSDINHNNQVGKVSLKEVALAMAEGPADVNVTHYKINLPESVQMTNGGTGLYKGQILLTNEGRGHRPANLVLVNPHPPHNVTVLLDHFYGRHFNSLNDVKVHSSGNIFFTDVPYGYYQHFKAEPQLPNQIYSFNPRTGAIRVVADQLDKPNGLAFSRDYKTVYVADTGSLIGKFGRNLTLPATIQKYDVDPKTLEFKNKRVFAYADSGAADGLGVDEFGNVYGACFDGINVWNPTGTLIGKFFLGTKSANFAFAGRGRLAILAETQIYLAHINAGGMSLMHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJR5</accession>
    <name>A0ABQ8VJR5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_827777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4495383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="36277" checksum="6CB757D42131C82A" modified="2025-10-08" version="1">MQAKIKAFISLQLLGAFCFFLVTVTAAFSPRVKRYATWYSFCVSWIISSLSYSLTLIVDAYAGAQGFHKDSHFVVGSMEWKAKRACTVQAVLIYATPVLTGFTSLAMCMHVLLYVRAALRVPMSRVKTVTTTMLVVIPYVIWATMFIVLFQLGQAQPNAVQLERSGYYCHLALPQPMAVCSSIAVLASISVAIVETWMAIAVHKYRDALPRTTHPMTFTLRVLLFGFVDLFALIVGLLLLIPSTWKFGVNFLLSLIPVLGIFIFGSQTDILRAWMFWKKPPSETASLPTSASRGSHYSDDFTFRQPSLSVICRRRMNIIIILRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJX4</accession>
    <name>A0ABQ8VJX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_946148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="121"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4496702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="430" mass="47957" checksum="A52BF78F92FB8249" modified="2025-10-08" version="1">MRSGNPHVSRSGLDTGSAHASSSSPSKVSEFGRMRIEIEILKNALSEQKKNNTKQAKKIEDLEAEIVIGKAKIDVLNAKILVQRAHFQTMDEREVQLRHLYESEHTSNEELMNEFETLLTCNICMEVFNNPFSLSPCGHTFCLQDLQEWFRKAPSMEYAMDDDIYDPEYIMNCQKSCPTCRAIVIGRPLPVYSVKDIINALQKAKPNGGSAADHNTISSCSKDPWEGLFPLTVSSSWSSSPYTSEDPWEGPLPDDLFPNYDEVEGESESGFADEETDGNPAGPAYEEGYGSVIDEEECNSLAYYEDMYGIPSDEEKEWYNHFEEMYGHLVDEEEDDCIGDEEENGHLVDEEEDDCIGDEEEYESPADGDDNSPADGDDNSPSDGDDNSPADGGYNSPADGGYDSPADKRAYDSPSDGGYAEEEEEDDMFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK15</accession>
    <name>A0ABQ8VK15_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sodium/calcium exchanger protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_866100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="540"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="574"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="149"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="473"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="360"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4496708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="630" mass="67699" checksum="79A8FCCA5CB94950" modified="2025-10-08" version="1">MEPAASLHHEHGSDIALLSDESAPPTQTTFTQATINNISPTVTSTAAPALPPLITVDHMKPDFKSVFRRSTPDSRRQRHERGEGYEPTSPREVVRAGTFSSLLTPSKKVGPSPTMLQSFRSVICSSWINLLLLCIPVSWALNFASDNDTLIFVFSFLAIIPLAKLLAFATDELSMRVGQTLAGLLNATLGNAVELIVAIIALTQCKLHIVQSSLIGSMLSNLLLVLGMCFFAGGVRFSEQGFGLVASQLNSSLLTIAVIAILLPAAFYYNVTTQTDSDEGQDLLKVSHGVAIILLFIYGAYLVFQLYSHASLYNDKNDIIKSTKYAPRPKKTKSNKSSVDHAHLNASAERLEMHVMPPYSSFDLAHDQHPDPEHGHGEGEGPSPGFSSPSATPTSSKPLIGRLTTKAWDTASTTAATFTSVASSAASLAGGRHKSKDVEKGLAPATSTAEGEVVVEIEEEEEEKPQMNLTTTIVLLAVVTALVSVTAEWLVDSIDGLTDTGVISQEFVGIILLPIVGNAAEHVTAVTVSVKDKLTLSLGVAVGSTLQIALFVIPFIVTLGWMMGKPLTLLFDPYESITLFLAVLTVNYSVQDGKSNWLEGMILMCLYIILCVTFWYYPGSDPSGLLNNCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKE2</accession>
    <name>A0ABQ8VKE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_980084</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CASC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09405">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="14">
        <location>
            <begin position="187"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="309"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="411"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="550"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="678"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="564"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4496847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="788" mass="86672" checksum="9D43F3BCA4B6DE01" modified="2025-10-08" version="1">MSAQVASSTSATARNMADNNSTSRTGGSQGKRRRFIRRRGRKPSLDSDDEVEREVRTDSESEDDLSSSDSTSDSDTEPASEDVQPNEQPRVLTPSTSQSPEGASHLLVNGRSQPFFGSSENWSEMVANEAEHGPENLPVIDFTELDSQVLPLPNQSRKSKKTQKHIHNRASLPTSPAQPQSADELEESQESRAPSSHSTTRRPPGQSARQAYQQRLEADPSYVPTVGEFWGHDDRLLDKNLRSLSGWWRGRWQGGMRGRVGFSRGSFRGRGGFFGSPFAGNPTAEQDLEEDGAQPVDLAWTHDGFEELKRNEEERSTSSHQQAHIRTPPSRGFDPALSRGGSFIGRGGRGAYSPPFRSRQTHAPDPARVWFLKKPEHMWTKQAEAFLFSDFSSKPRAGHPASIRVKLPSQKTAPVRVPIQSVPRASTTKHPNTSPESDSGDKILVVRLPKSVPTGQPVAAETISHPPRIDEPSIEEVFTVRPQLVSPKLIPLPEQQPAIKEASVTLPNGAHTVSSSISSVDPAIQQKLEQLSLEPQKTDPTRWVQTEEAVMRNPTGTVPEEQQEQPPLSSMQHTFSPSDQVSPGYGSPYQYAPHLPPGLAINSAGMAYEVATGRPVYLQAPSNMYAAPMMQPVPFVPSHVHHHSAVSSSEFIPAGTPPINGGYMEYTPTPSIFSFPRQSSRVQIRAPDEPKQNARSTSTSEAVDLAAGQQSSTELRSDAVAFEPAEQYYSEGDGLTAGSHQHQVQDAMMGYYNPYYYPDPSYGYNPYLDMSQVAPYEMFPPQGTVYYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKM2</accession>
    <name>A0ABQ8VKM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_902547</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05500">
        <property type="entry name" value="Bromo_BDF1_2_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05498">
        <property type="entry name" value="Bromo_Brdt_II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043509">
        <property type="entry name" value="Bromo_Brdt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="217"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="323"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="857"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="1072"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="8">
        <location>
            <begin position="1243"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="11"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="484"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="699"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="750"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="961"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1159"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1197"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1321"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="970"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1166"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1205"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1340"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1383"/>
            <end position="1395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4494286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1395" mass="153065" checksum="6D9A9A9865A809BD" modified="2025-10-08" version="1">MADMDVFAAMGISGFGKSNQKKKLDPSRFDKNKRSEVSAPVHAPVTASLAGSSSLPAEYKGEKSDDENDVGPSPPAPQTSTKDDNEEEPEYDPDEMENDDVDNEVPQFPTTHELILKDHTKVVSALALDPSGARIVSGSHDYDCKLWDFGGMDTRCKPFKSWEPSGSYHIHDIKYSNDGQRFLVISGTLQAKLYDRDGEEQATFIKGDPYIRDMKNTAGHVGELSTCAWHPKNSQLFITSSADSTIRIWDVENKRKQKTVIVVKSKERGARTKVLSCAYSPDGGMIGGVCLDGALHMWNTSSNFVRPNLSIESAHVKGTETGSLVFSVDGRTVLTRGGDDTVKLWDLRAFKKPLSTRAELPTLYPNTNAIFSPDDKYVVTGAGASVKGGTGRLLFMRKDNLEIAKTLEVGATPVKVFWHSKINQIVTGLSNGQICVLYSPHTSLNGAKLLLNKGPPRKVTIEDMSDALAAPAILTPHALPMFRDGDGIVRGGKRKREKDRMDPRKSRRPELPVTGPGKGGRVGASATQHVVQNLVRDTTRDEDPREALLRYATAANEDPQWTAARMERKSSTEPTLVGNEKEKEALRIRMETGDNSSLMDMNDAPVISSDVDLSGDQASLIDADAENQPLGNEVFGSPPASPSTPVSNQITPEVKIDVHYEDQESDAHNELLPIEPINDTQDKTSQDVLTVSEVAAELDSAGSLPPETPMETHDSNDTTAVPINDINGLNGVNGVNGVHVDSDIIMEEHTPATTPGVSGGSFSGTNGSTAHTTPNDILDDDDDKPPPAKRARVHSDADQASIAHSATPPPPSATTLATPVPPPSASHDPFTPVSSTGSSMLTVGQYRFCQSTIRSLKKLKDASPFLRPVDPVALNIPHYPSIIKNPMDFSTIERKLTASNPVKPDPNSLNPRYRTAEEFVADIRLIISNCVTFNGPDHVITAMSRRVEEVFDKQVKNMPTVDAPVVKKQSPPPPPPQRPVAVAPPPVSTPALVKKVPPVRRPSTSLPTIRRNEAQEVIGRPKREIHPPAPKDLPYADAPKKQRKVKLVKDSAGSVEQLKYCSKILSDLHKKQYYTIANPFYQPVDWMKLEIPSYPKIIKRPMDMSTMRRKLDAHEYRTASSFWDDFKLMIRNCFTFNPAGTPVNQAGQELQRVFDEKWKNLPPEPMSEDEEEEEEEDSEDERARTIAMMESQIETIRGTISQLKSKPKDKKKKVKQEKAPVPSTSKASHPKPPKQPTTSKKKGKKAVTDDDVLSFEQKKELSDTIDKKLDPAKLERVIQIIHEGVPEIRDSTEEIELEIDMLPTAVLTRLYNVVVRPLKAAPPKRNRPGKGTGTGGLKRKSMDEEVEAEKIRQLEQRMRLFDQGANGAAPSGAHAHDSDHSSDSSSDDSSGSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKS2</accession>
    <name>A0ABQ8VKS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Signal peptidase I family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_919298</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S26 family. IMP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052064">
        <property type="entry name" value="Mito_IMP1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383:SF16">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383">
        <property type="entry name" value="PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="7">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="7">
        <location>
            <begin position="73"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4494331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="132" mass="14326" checksum="F0D8117146AA7858" modified="2025-10-08" version="1">MSGPSMLPTLAASGEVVVEDRLSLRLNPASLARGDLIVVRSPIDPTAIVCKRVIGLPGDVVCVDPTGLKAPSTEHVLVPKGHVWICGDNMTHSRDSRDYGPVPIALIRSKLFARVLPLKDRIIFRNPMRVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL79</accession>
    <name>A0ABQ8VL79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Meiotic nuclear division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_229256</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MND1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005647">
        <property type="entry name" value="Mnd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040453">
        <property type="entry name" value="Mnd1_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03962">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026991">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mnd1 HTH" evidence="6">
        <location>
            <begin position="15"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR026991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4497152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="204" mass="23345" checksum="0A574EA33D2A4831" modified="2025-10-08" version="1">MAPRGLSADEKRVKLLEIFHETKDFYQLKELEKLGPKLKGIVSQSVKEVLQSLVDDGLVQGDKIGASNFFWSFPSHQGAVIQGRVDNAKEMKISQQTQLLEIQQSIEREKSTRIESESRTAAIAKLQYMKKELAKLDEELTAYGACDPVKLEETRRAITLGKEAAIRWTENYSALLPHFLHHSMASIEDVRKYLEIDEEYEDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL98</accession>
    <name>A0ABQ8VL98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_230632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="365" mass="40339" checksum="7C3AFF17A31A1C2F" modified="2025-10-08" version="1">MSNGNTKDVSGSSLLRTRSAGDPSFSPSDLGVPRTGASHLSSDHFFSSTVITIPKRASRGPHSAGPSFNAFFPESIPKKRENQVIAAICSSPRIPPPAILHPPPTPIPMNNTIPAPPLRRPVHTHHSPVARLLHFFGYGNDASKVRKELVSLIWRLGWGFAQMVSIVVVLALFAPKASPTVPGANEWTACNRPLGVWSCLWLGRTIVGGGLLGMDSRPIHNRNTRIDPESGQRASNSEHLEQTRSHNPQQPPFPSINSPQTQNDHLPHTVMFRRFSLFSSMYGIIWFLTAYILVCTSLKTCRLSSPHIWWLTIAILCTMYLKFILLSLIVSVFALVFSIWNILLRCTTKSNTENTDHQTGHQEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLE9</accession>
    <name>A0ABQ8VLE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045828935" evidence="2">
        <location>
            <begin position="23"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="234" mass="25453" checksum="9C8975B0E8496060" modified="2025-10-08" version="1">MVHSCSVLTAVIAVGVAPSVLAIPVPPASTNTGGPNSGVAPTPSNLLVPGQNIMPSHTSNSPPPNVNFLLGQPSSNDRNVKRAFEKHSRYLDITVQDNVDSEEPNEGLITSSVRREILERDSDIDVVTAQKELASTNYDWSEFLENTQQGKMIKKLDNDAQENWKTYFLSVKGSRERSTNPHAPQSTTGPGSHGHNYGNPVDKNMKPGGGFTPLMRRARSRARASPYNHVEDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLR1</accession>
    <name>A0ABQ8VLR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_865655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4497349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="124" mass="13821" checksum="59AA5A769B6C9D20" modified="2025-10-08" version="1">MLLHPSGKKEVLEMFDFQCTKRQGSTCNETRQNLEDGLRLQPNIGSDRSWVWKVAAEYSETPPTSETLAIRFANSESSILDAPKFKKEFEAAQKTNAALRGGAPAEASLMKEKKDEVEKEEKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMJ2</accession>
    <name>A0ABQ8VMJ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_821790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="57" mass="6451" checksum="BE67047B2D2BB007" modified="2025-10-08" version="1" fragment="single">MESPEGFVKPGSEHLVCKLKKSIYTGVHPSIMELEAAGDRGPVYHRIRIHWPIPLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPJ4</accession>
    <name>A0ABQ8VPJ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7082 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_818734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055509">
        <property type="entry name" value="DUF7082"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39463">
        <property type="entry name" value="MEDUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39463:SF1">
        <property type="entry name" value="MEDUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23305">
        <property type="entry name" value="DUF7082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7082" evidence="1">
        <location>
            <begin position="81"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="313" mass="35888" checksum="C49ACB62AB7C62D4" modified="2025-10-08" version="1">MRAKYPVCKDVDEELYAQTPLLQLVTSLDSMCVAWEPSEKRVSRRLVRFTKVQDGRKLIVSCEAISQDDYRESDSVISCINDEFPVEEKNRIRRNLEGLRPTTVSKHKQGFENFFQRIMEFPDPKPRNIEKDLKVFEWSLLGQALDKILSKYHVYTSSPTDSTVSLPMEPFEDAPYPRNVDHQVAHDAKLDRYPELVHPTPTSTMKFEPGLYEDRSLLFLQPHSDNMECLSHPATPFVHHGSAAHTPLTSDYQSGHWTPPDHMVSNELAIGEYRHLTDFQYPGPHPNGDGSDYGTYLGSYSFPGMTETPLAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPU2</accession>
    <name>A0ABQ8VPU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_757475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4498399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="57" mass="6472" checksum="5877D14912660D8B" modified="2025-10-08" version="1" fragment="single">LSSPLPGITKPAIRRLARRGGVKHISSLIYKETRGVLRIFLENVIRDSVTYTEHAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPZ9</accession>
    <name>A0ABQ8VPZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_825509</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000026">
        <property type="protein sequence ID" value="KAJ4496675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="552"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4496675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="683" mass="75230" checksum="7665FF75C9407C8C" modified="2025-10-08" version="1">MAHSMTPKDRHRPSNLRTISAASSIMGAEGIMTPHSEQSEREQLLETDIERLGGISRDSQYGSTSARAIGHKPPQGRKKLRKRVKYYIPSLSWIPNYSASLIGGDLLAGLTVASMLIPQSVSYASSLAKLSPVTGLFSASIPGIVYAFLGTSRHLNVAPEAALSLLLGQAVDDIRHDLDDPHSDKGDAIGLAVATIITLQVGLLSFIFGFFRLGFLDVILSRALLRGFIAAMAVIILIEQLIPMLGLVPLERLLHPATTIEKLLFLVENMFTHGNPTTTMISFVALGTLVLLRFIKGCFKKYWFIYRIPEVLVVVVVSTILSREFRWDEKGVDILGSVKVVTSGSFFQFPIRSSNMKYLRRTTSTAVVSAVVGYLDSMVAAKQAGSRFGYGISPNRELVALGAANIGGSLIPGTLPAFGSITRTRINGDVGGSTQMASLVCSAVILLATFYLLPLLYYLPKCVLASIITLVVFSLIQETPHDLIYYYRMSAWMDLLLVILTFVLSIVWNVEVGIVVSLVISLLLVVRRSSKTRMTILGRIPGTDRWKPINENPEAEEDVSGALIVRIRENLDFANTAQLKERLRRLELYGVDKSHPSEDPRRTQATVLVFHMADMDDCDAIACQIFYELIEEYRNRGVGIFVTHLRAEPLKAFEKAGIVKLLGADAFEDNVADAMAKIRPNRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQL4</accession>
    <name>A0ABQ8VQL4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_793095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1234"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1326"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="772"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="973"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1107"/>
        </location>
    </feature>
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        <location>
            <begin position="1175"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1266"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1326"/>
            <end position="1345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4496900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1424" mass="152029" checksum="8CB481D150C52D16" modified="2025-10-08" version="1">MASPSRPEPMNATKHHPKVNVSLILAESYFVAGEYISGKMEMDCKADKGLGIGMIMIELSATQELTSRDHSARSTFIHARRLFQGPGLPPSNAVQAHPLPGDPPLPLHYHQAKRGHSTFLFRLPLPATSPSSISFGSGLASVKYEIRASVGVYWKGERQLVTERKDADVVEAYDEERIGQDEPEITVVGENGKIWCQARLIGGILIAGESACIELQVKNHSAKKNTGLSISLNRSLHLPNLPADEKPLHIGDTVTTVPFRGPEYIIPPGVEGVASLVFDVPKSARGVRGGLLVGDENEALKNGKSPRTTQGLFEVNCVIAVKMLMGFGNKDILIEIPAVVVHPSALPELPLPEEQDPGYTYYDQQQVYQPALIPYTTQSPPTSFPSQSPYPEQAQVQGTYVLYPALPMSPGPPGPALATTSYVDPNQNLVWLPPSIPFIPTVTAQPYLYPQSPNHLHAEYAMILETPAPYPRDDDIFLRSPPQPSSPGLISSSTTTVAALLSPPLPELPGLPPPSTHQDLTSMFNYPTEPILMHSHMRAPVSPANAVHSSSSRVGPGMYGSATGLGDAPSHTGITGIDGEQGMMHHTSARTLRVTSQTQRRGRSTSPIGGQSHSLNGGSDEPTSADVFHPTLAPLPPLNLDFKPTTLRTPLHSPRPVLSPKRSFTKVTEVSNAGEMVSKSVPKSERVEQLERMADEVETRVRDLSSDLPPSSDQKQLDGWAEEPPPVPTITDKARLPLTKPRENDYFSIAPAPNQSALNGYGSPKKDLTNGLAAPSSSTSSRPRSRSRTPPTPATPTLTAVVTPRKSLATGYMNVYSTKAVKAVKGKSGNDQSLLGLGLGVEGRAESGLDALERKLLAEVGTRKIVDEKRPDVWSVLGSGKDKTLSPNDTNNPGSGRDSGVGAEKTEKPSPIEIPRRDSDRDPFNDSAISSLTLPDCGDIEPVVSNSNSQPDVADAWKSTAAMDKVHGNSNSELDRDRDSDEKTHKGGLRSKNNKRKKHSSKGTLKDGQDGKEDDDGETREAKKKGGKKKGKDRSSASKGRVAAWLGGVGAEPPLDDVISPSPSPQPPRIVELPSDIELLDKPHADLQGEPRDTDSTQEKEHRKDSDTAGLPPSPDPRSSGFVPIGTLKRDIYQRTLVPKDSPMASTSPSEDAKRITDIWNHRDTARHAGPSPKFNGTSNDLAKNPWQSVVGKGRLSVLPPERSDPEIKYDIRSARGGKGGRVTAVAAIWASGSVSASGKKPTAASPLSTPHSPGKSSKATAKVTSPFSVPKFPVSVSSSSSSGSGDGINGQRTTPTRRNFGVGVSVKVASTPVPAVISSSYAKPALSTTASLSRPTAAASRASPIKVPPTISEFPSEVRLESKSSDPASNPKMARTGLGLGAGKAANNLRAVTSSETKKTYTHGEHLAFGQARLRDLIKKYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQT5</accession>
    <name>A0ABQ8VQT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_758793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="574" mass="65156" checksum="2DCD76E76C82526E" modified="2025-10-08" version="1">MGSSELSDALNPYFTQPRGTHSSNANYSEPLQPVMQPSQQYVPHRSELELAISELPATRHRGSFEGHDAIQELLRVVTQTSQAQENERKRRQAWEQEQEERYSQRQAELERQMLEMQREIYSLRSAFTAGPSAPTPSDLQHSSDQFGSQAPRPATTRSHGQYYSPISPVPQISDPFNQGSSSSPIRLYNPSTANYPMSASSQYNSPMSPAPSSSSSPLDSPMIMPGSDSPIGTSALSPELPSDKGSNNDDWLEDPAHIGDHYQRKCRSIQEAMRRHMLRLMDVGDNQNLPDSQPEGTIRDPSQPIRFVWEKTMKQSVHNIRMKSFVLEDIKQNRQLYNELPDRDFSKNILESAFDQGFTYLRQKFKSQRDVKEAENMKFRGDQRAQNARRLARRKKKLDTRAAARLRIPNFERATFDGALQLECMSSEESDDADVSKHTTLYTRGYLWRSSRLLHFFHALDQEDMAVPKRGSAKMNRAIGTPKESIGLPPKGVSSWMISRRWIRATQVKQPDLSEALERLVCGSPNLPPETVFQLGEESEEEEEHNQAIQDEVSGQLHIAMPQHYSSSLHNALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VQW2</accession>
    <name>A0ABQ8VQW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_190075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000019">
        <property type="protein sequence ID" value="KAJ4497850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045909186" description="Hydrophobin" evidence="1">
        <location>
            <begin position="19"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9458" checksum="5D8248E6CB84DE76" modified="2025-10-08" version="1">MRVVFLTLAAVGVGLVSAVPITPTSDSLLPCAVCPAIAESDDLLPFILTQSTEGLLSIILQCDYTNLLGSASCSYFVSTTKYRRYTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VR72</accession>
    <name>A0ABQ8VR72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_935004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="151" mass="16376" checksum="A8F19A3C50535F1C" modified="2025-10-08" version="1">MVIHPPLVLTRRHPASQESSSQITQLEDDPPPPPRKPLTRRHGPSEAHSSQPAVTEMKDDQPPLSRKTHEVICSPVSVPTDFAKVVLTSKPASPSNPNILELTMSAFVLPNAPIPDNTPLEKFVMPVEAVERAAALALFSDAVKSTSKHIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRF1</accession>
    <name>A0ABQ8VRF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_758126</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4498045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="14">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4498045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="572" mass="61690" checksum="79D1CE7B24D88267" modified="2025-10-08" version="1">MVLADLGRKLNAALSSLNRAPIVDEKVVDATLKEITSALLESDVNVKLVASLRQKVKTKVKAAFESSDKSKDANRRNAIQKAVFDELVHLVDPGVEPYKPTKGKTNVIMAVGLQGNGKTTTCTKLAVYYQKRGFKSAIVCADTFRAGAFDQTRQSATKAKVAYFGSYTETDPVAIAAQGVAKFKKERFEVIIVDTSGRHRQESELFEEMVQIGEAVDPNMTVLILDASIGQAAEAQSRAFKETADFGAIIVTKMDGHAKGGGAISAVAATKTPIIFLGVGEHLHDLDKFSPQPFISKLLGLGDMQGLMEHMQDLATQNPDKQKEMAKKLEEGKLSIRDWREQISNVMNMGPISKIASMIPGLPQELLQGSDEEGTLRMKRMIYITDSMNTLELDSDGSPFMEMGKDGKPIGLTWRVTRVARGSGTSVREVEELLCQYRMMANMAKQAGGKNGWLSAMQKMQTAAGGKGRGANGMPTPAQIQAMQRAMPPGMLQQMQRQMRSGGGMQEMMKAMMQSQGGDQMDMEEMQRMMSQMGNGIGGLGGLGGLGGLAGGMPNMGDMFKMMGMGGGGGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRX3</accession>
    <name>A0ABQ8VRX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_755473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="38675" checksum="385E7E0E9001597C" modified="2025-10-08" version="1" fragment="single">GSIMDAVRISDNKPVMLKAVSRIIHPQEVKIGMYFSDKSIASDPRNHCIPIYDVFPVPDSEMDLIVMPVLRPFENPQFDTGIQFMHEHLVAHGDCTEMNIMMDGSRMYPKGWNTLDPWQAREDPFRAAKRAGFRMQFWPKYYLIDFGLSHMYSSKRTVPPLERILRGGDKSAPEHAPKYKRANPFSTDIYYIGNLIRENFTERRNSSLCKRFSFLKPLVDSMVQNDPVKRPTIDDVVMQFDAVVRKNRRHLKFRAAACDLQHYQFTDQIPALFRRFTKYFVMRRSLPVLPQSERHLSPELTWMYSGPPTEYPEGQQRPMFLYIHDLDDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRZ5</accession>
    <name>A0ABQ8VRZ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_755202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="16306" checksum="06E66DCF9BCF02C7" modified="2025-10-08" version="1" fragment="single">LKIRYESLETWWLAVDILHCNPNFHGHPRYDYIIFSGILGPVFAQLHYLLLCNACDSQYPIALMQAYKIVNTRSCIDKDLGLLRIRKEHNLEFISVRSIVRGAVVLPISSETDDRFVWDPLDGDMFLRVKKYFPGFTDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS52</accession>
    <name>A0ABQ8VS52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_900652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="405" mass="47579" checksum="7E7384D01A0FC06F" modified="2025-10-08" version="1">MDPIFALKFKIDRTKQDEKREAEERKRAMKTNQLQSVEIFFWYKDDTIPKHFVPCAISDYPFLNLAQTRTHYDNDIISKPLLQRLGLGPGDDIDRWSHNTNSWCTDITTCAIEIDKKRRPILLKKPEVTTPLNLERYIERHDNLKRDKKVLKRTWEEGLQEKQSIEEGVMKRICSPKPKTRQRALTAPTHTQSLSFITKHFEPILYSPTPLPTPSPPPYDWYQTEAHAADMRQYLKETLLYVKSPQPVTLESPQPVMLKSPQLVTPKFPQSATPKPDTRGEDGTMRAQLKEEHRVCVSGVVASGRPWPHGMIVKDMIDSFTLVDSHYWKSRYPHNQQDRINEVFQGVSVDKRQFHKQRRAWQGMTRDEWAYAQSGGHEQEWVQWRKTSKGWKEENERNHRRIAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTC5</accession>
    <name>A0ABQ8VTC5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_31797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000010">
        <property type="protein sequence ID" value="KAJ4499627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42697" checksum="E8DC6EB98E65470A" modified="2025-10-08" version="1">MQQYYSSYPTQSNYYSQPYDGAGPYNGYTPYTSQPQVPVWGSTPYAPNAGLPPPMQMQSGAPPPTPTAHRSSHRRRTTMPSRNTSQPLKSALKPSNSIQMPTPSSPAPLHRKRAMSNPKRDYQSMGMPNAADYTTPFSNQGFHLPEDESTYMFVSFHGTNELHIENLAHKAMDEIRKEIFGMWPGGLELDELQNTQWRVRFKNTPWSLRDENVQWAWRMLVKLFTLFEERGYSYNTTLDVGTSSPRLHFVASSLSICRFFLATISNGGRTFTLIDPPMDVMRDLTTGLQGALPGHISKDEFGRLGETNLRIVELRRPIYGGNEITCNQFHCQILRILKHIGYMLCATLPMARKGPLSAIGIGTRQELLVLKSVKSSPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VTF2</accession>
    <name>A0ABQ8VTF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_915990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="157" mass="16819" checksum="4891B93B6AE2E7A9" modified="2025-10-08" version="1">MPAVTFPMLIDVTTTTVFASSPVTPTSSNKSSTSSVPVAAIAGGVTGGAVLAVAIVIAWIIWGRSIKRQKDELRITKHNTMKNASTFSKPRNYSYRPLFWPPSNTQVKFADESEKKSPAAANPTYKTPSRPKLLTPCVSFTPNTRITPSAEPPAGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU22</accession>
    <name>A0ABQ8VU22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endoplasmic reticulum protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_753227</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="70"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="90"/>
            <end position="109"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="218"/>
            <end position="238"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="387"/>
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        <location>
            <begin position="408"/>
            <end position="426"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="446"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
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            <dbReference type="SAM" id="Phobius"/>
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    <evidence type="ECO:0000313" key="8">
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            <dbReference type="EMBL" id="KAJ4499881.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
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    </evidence>
    <sequence length="510" mass="57135" checksum="38BAFD7D90505C02" modified="2025-10-08" version="1">MDALFVPLAGAVGASVDQVKLISCLLIAYPLGSVFVRIPSDKPTLRHLFNISVSLFYFFPMLGMYTGFLQLLGDILITYFAAKFSSTSKIMPWFIFLFILGHLMFNHIIRVIYDLSYETIEVTGPQMVLTMKLTTFAWNVWDGRRDPKDLDKWQLEKSVREFPSLLEFLGYALYFPGVLVGPSLEFTDYINLVHERTFTAPGKHEGGRRLPAGRKRVGYRKMVTGLAFLGVFVVFGGSNNYSVMVTPWFAEQSWLKRVLLAQLYGTCERTKYYAIWTLTEGASILTGNGFTGFTPSGQSTWNGAANVIPTVIEFPSNFKVLLDSWNMKANVWLRECVYKRITPKGQKPGFWSSMLTFATSAFWHGAQVGYYLTFLMGGFITSAARLARMNFRPFFLPAEGQPITTAKRLYDFVGALVSLLVLNYVASPFMLLTWENSITGWTRLGWYGHVVVMGSLLFFYVGGSGFCRSLQKKRGISSKKVASASGAATPVAEKTFQVPPALDKIVPPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUT3</accession>
    <name>A0ABQ8VUT3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_863465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ4500138.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="65728" checksum="591D8F2585088496" modified="2025-10-08" version="1">MDDVSVILLSLDADTTITKVSCIAVVNADSLCYQAQKRVQAAFDTKGASFVFFMLNEPIGVDEEPAMAARLGHFNYEWIRWTKGTLREALKTNPKPEVIQVVAITFSEFRMLPPREFLPELPGGKFFQERPPKAPSSGAEPKEFAQSQENEKTRIHIDRPRKLNNTSLPIALLVPSFGNFQTNIKNIAPSDRAILFATKMANELCVIFRDEQEREQKFCSILSEFLGEDISNATTIGDFKTDDGVFHKYTAVDMNGAPRLFIKVRLEQTGTGDPCLQVSLDYLENTRRVRQNVVSRNEKAAAWFRARLPSILITHAGPNIQILGGVMTDRPQIEVLSASVPMYFHVSNQDLFLDLARTLTALNILFSDLGKLYDNPPPLNPLFPVQHEYPYPRRFKCGNQVITFTYLKRVDPIRLVFKVETEEKKLLYIKYTQRYGAEAHRNAYELGIAPELLAYDDTLPGGWKMVVMKPIPRGYVETDGIRGGEEQGRVQAVVIAKMRPYFDEGFVHGDLRAANIFVDGERQHIMVIDYDWAGRNKEVTYPPDVRSSIDIWRPRVELSLRPIETEHDCQMLKHLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUX3</accession>
    <name>A0ABQ8VUX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_531304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000007">
        <property type="protein sequence ID" value="KAJ4500181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="154"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="451"/>
            <end position="489"/>
        </location>
    </feature>
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            <begin position="548"/>
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            <begin position="610"/>
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    </feature>
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            <begin position="717"/>
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    </feature>
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            <begin position="919"/>
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            <begin position="1293"/>
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            <begin position="1357"/>
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    </feature>
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        <location>
            <begin position="1492"/>
            <end position="1516"/>
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        <location>
            <begin position="1549"/>
            <end position="1682"/>
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            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
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            <begin position="154"/>
            <end position="164"/>
        </location>
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            <begin position="165"/>
            <end position="175"/>
        </location>
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            <begin position="196"/>
            <end position="207"/>
        </location>
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            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
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            <begin position="552"/>
            <end position="563"/>
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            <begin position="1357"/>
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        <location>
            <begin position="1380"/>
            <end position="1394"/>
        </location>
    </feature>
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        <location>
            <begin position="1407"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1496"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1549"/>
            <end position="1563"/>
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        <location>
            <begin position="1569"/>
            <end position="1618"/>
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    </feature>
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        <location>
            <begin position="1628"/>
            <end position="1637"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1646"/>
            <end position="1661"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1670"/>
            <end position="1682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4500181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1682" mass="175123" checksum="C3C93930C38108BD" modified="2025-10-08" version="1">MDSSPISPPPLASPNPLYSPNVPSPIPNSPIPSSPSFSPRPTPPVRRASTSSVTIPIPGKSILKKPPPPPTGLLSRITSGISVNGIGGMSMGGLGKFFGSGTGGNATSSLNSNLATIPEPPLDTVPSSLPPLNPALKRAHFILPHMAVVYPISSSAPPRTPTTQMEKKAVENRERERRRKVVSGDSTGSGGSAVSITNQSESSGYTTPVNEDYRYGLSTDSLPTPIGASGAGWWNMDKVGAFYKECCVASDELPDPAISKALLRYSTSAAASTSLTTLSTNPNSTNNALTPITANPNPISVLPSSMSASAPRTLDLTGISLSLTQAEILADVLSIEWGLRTLILCESNLDVIILKPILHALLLNNTLIYLSVASNSGLGRSSKSSVAGGGGGLNFSGGFGSLKGAVSGGAVTGWVVLEAYLSKSRLKVLDLSMNVLDKKAMESVVRGALGSLGDDSTSSSSRSPSTESLSAITEPHDSHSHSHSPSPSVISLTLDSTTIKSSAALDVLARAVRTSPSLRTLSLRNCRIGAMGSRGGIAVSLMVRDWPDSVPGGTGPSGNGSGNASGSNSSSASVSMLNPLSLNPGNTSHPQSTTSIQRLRRPAALTNLFDSVTSPPVTSTPTTNSAFQSSSFSKPPLSAKPSPSAPLQKPLLPPPRHPVNSNMESTSKPNYLPPPAAHPLSHSSNLPPPPPIHPTKIPPQTTYTPYVPRSKRAVLGAAPGTESVPPTPTTPSGPLTPMKSATPFTHTPITTTLTTVSRGGVTALTSTNDSNNLSSDIASNHAIDSNSNSLNPNVINAITHNHGGATLGAQPMPPSVAALNSASAALLTQVRALDALPRIGSLRVLDLRGNELRNHITYLAQVLKRNRTLKSLNLQDNKLDPKALVVIAEALKYNAALEELDLGRNPCCGVVGGVGIASGGDPTLTRSSTVSSTNSTSSSSSIRSYASSYTPSMSTPTSSTTSFVSYKPNPPSNASLTTAHTQPRSQLYSNPHPSTTGSAFSSHPSSAPPQAQPNLGLEGLHALRLALALNTTLTRLSLSATHLGDAGAIALAEWMGEYRGLRWLDLTRNSAAEVSSKSLGLSGVSGSGLGGLGQAGVMALAQGVKVNRTLRCLDVEIPPGVEGYAKLSREILNTCIRNVEASAREQAEQAERGGENREQLDDWNITKDPVHRAKDCMEDLKKYLKIVSSTNSAASITSTTFSSPTTFNTSLYPHPHANADVETLLQRSKSALDDLTNVISGLLEDTSELSFDGPIKEAKMQEVLELSDVLSALVGNLEEVIRKNNAQESVLNEKNEVQGMAGVRTNEAVDVPGAEGKESGRTSLPWKEKPSLRVEVPLNHPTPSVAFLTSLSSSMSASSTLSDSTVSSSGPTFTITDSPTPSPPPSTSPRPSSPIHPVQASDASITYEEHDVLIPTSDKGKARAPPEPERHEPVLSPTAVLLRNGVRGASSLGLIGSPLSSLGVGIGLSDDGLSESEGEGEIEDEYEDAIDRAGEDEGENGEEEAEAGVRSRSWVAEEGEVFRKGNVLLGPEEMEGEYDGEELRRELLEAMVERPAPRSLRIDDPDDYGSALTPSSPSAGGSALSTPLSPPHSSASLHSTSSLSSSPSISSPSTPLASHPEHDLRLTSPSSSKSSMSDGTTPTQESTASSAADVSSSSSFAMVRPYVPRTRSSFSGMTLNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VV00</accession>
    <name>A0ABQ8VV00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_63085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045635558" evidence="3">
        <location>
            <begin position="22"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4499407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="380" mass="39208" checksum="2FB0777AEAEAD709" modified="2025-10-08" version="1">MARLLTLVSLLFFSVGSRVAASPCVAFDASWNLYAFGFNGKDYNAGTSDSWASGTASDVTASGRPPFDGANTTCYLSQFYNGIYVLNGDSSNPSNVHIYDPTAKSWTTQATSGGPTDGYSAVLDHDTNVFYVLSDSGELWFLSFENITTAAQSSTIPWTDVEKAGFDTTNYEPVMALANNHVHFLDVPGVAAGSADIFVIHFSWFQPDSQSYGNFPAQHGQTASIFEPANDGLAFAYIPDDGSATYIIDVVSNTTATMAGPSTKDSSASYFASDAAIVQLTSSGAVNYIPYTNSSSDSSASWSTVKNLVSVAPTSSASSASGSASATKSATGSAASGTATTSTSSSSSSNGSMGVAVKSGTVVVGMMSALLLGTIALFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVA2</accession>
    <name>A0ABQ8VVA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_914368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4500298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="114" mass="12707" checksum="77B4CD729A88334F" modified="2025-10-08" version="1">MSKRLIIHLHEISMKRRIDTAADAALSSSQSISSVESMSHVVRTQFKPKASTVSLDLTIPDFDLEDVELGTDWAEDGSAHVRVEKTVQVERRSRMVYELGDDSITPGPSLSRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVC7</accession>
    <name>A0ABQ8VVC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GIT Spa2 homology (SHD) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_811052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000006">
        <property type="protein sequence ID" value="KAJ4500331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022018">
        <property type="entry name" value="GIT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013724">
        <property type="entry name" value="GIT_SHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039892">
        <property type="entry name" value="Spa2/Sph1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056439">
        <property type="entry name" value="VBS_C3G9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601:SF0">
        <property type="entry name" value="PROTEIN SPA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601">
        <property type="entry name" value="SPA2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12205">
        <property type="entry name" value="GIT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08518">
        <property type="entry name" value="GIT_SHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23742">
        <property type="entry name" value="VBS_C3G9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00555">
        <property type="entry name" value="GIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="3">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="3">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="754"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="754"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="785"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="809"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="819"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="967" mass="107353" checksum="1465B0133DBC322A" modified="2025-10-08" version="1">MKRSQSRAPSPTPTAFSGISNYRTDSYRPISKNAPPVPQIDYRSISKIHFDELSQYLAAYLARALPNSRSTARQKLTRLTIQQFHELSTDVYDELIRRKSDKEVPFLPVREEFHPKRNQARQKLATLPTSRFEDLSSDVYFELARRYPEFKEDPAGRTSVGSNYDDYPAPGFPSTTTPRAANTSRTSGRASADRPSDSGYGGSVSSRRPSQDRRRPSEDLYGGRMSDDNYASSISSRRKASQDTTTRRSEDREREREYSRRPSAAASMSANSDSTATAAQSTMATSGMIIPNTSTMEEEYIEVPYGRDARESGSSTNDERDRSRDRGQTPGFSPGFTDDEPDSASNYASPLSPNSPAVGLSGLSARLKTDEEEDGPSTRGGDDFYDKPLSYGRNSANSDRSINAYSNRMGGRASVVEENEKMRRDYEFRIATMQTQISNLQRDLGDSQQTQFKLSESEMRVRQLEEELASVLRRTEEQTSVMRTLQKELDDLQETRQREKERESRRAREDEDELQILRDRLESLEEERANGRGGAADAEVVEQLRSDMQGLLIEVSDLSRRNDELMTAKDSDLVVIRDLDNQLKEYKRKYEQAKTELRSVKATSQLFLQAPKIDKLEDQLPVSADGGILDIHVTAFLSAVDGLLTAGRSNAPTRVLSPMKYVVNAVTNIIDDVRAYERRPSRADVDVDTLHMLRERADATLSNLVTASKTHATSSGMSPVSLLDAAASHVAATITDIGKLIYIRKATKAEQEQFASSTYSPGPSATNGFTPSLRSVNEKDHQRKGSAASSAFGSSSRYDNPSMYPSGRSSDEHARRTPSDNSSSEKTNSPPPIFDHPPNTASTVSDGDGTEDNWAEVKPYLETQTETIVYAIQSVLSGVRSPTPSPTLNENITQIITIVFSIVAVCKDNFPPASAQQGNEILQELSEHANTLSEMQALPEVTKESRQVMAKSSFAIANAMKGLMKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWB8</accession>
    <name>A0ABQ8VWB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_751335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF517">
        <property type="entry name" value="RNA HELICASE NONSENSE MRNA REDUCING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="392"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="643"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="495"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4500653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="929" mass="103978" checksum="9F4FE02ED69494C6" modified="2025-10-08" version="1">MYTGILHSKLILHQNFRLRLSNFSLPSSKRYISRRIDEEEAFIATVHGLTRQNTPPLTLERSHSAERYDWRLRATSRPRNDLKSNTGNGDSPSLIKRVKPPQSALEKSSPYYAAFNEYKSHFLPLLQYEQDEEESLIRERLGTWSLPKLKDEGYTLTGLSAYWLEGTRFGKPMASFSLGPGLHLPEHKFLNGTRVLLSRIDPLKEEPSRGSVLSTTSTHLTISFPDRSFSLDVPEGSDGWRIDLTESDYVFELMRTAIDSYKFDVRKQEQTGIFLPSSGLEGQREREYILMGTHLRDVLLQSSQPSESPHAHRALQDAEDPNYVERDVLEHDYHPDHLSLPTGGFQEQPPSLGDNHGAFHDDMLISSWANRYSHPNPVVIEGDPQFEELSRMNETQKRAMAMMIGERISLVQGPPGTGKTLTIISTIKLLKMHFQVPQPLLVCTYTNVAVDNLVEGLAKAGLKPLRAASAGKTKESLTKWTLEYQMQLHARYADWKDLEDRVKKIGDTLKELRNKIQNLERKMAKEGLSSRETQIRDGMLKNVIRQGRSLDATKRRSYGLEQAMVKDILNNADVICTTCITSASAALNAIDFPVVFLDEASMSTEPASLIPLMKGCRHVALIGDHKQLPPVITSPEARSLGLAISLFERLAEERVVPSIMLNIQYRMHPAISHFPSLEFYNSSLLDGTADTFGYVLPRLMPPSVSPVLLPPVRTSARPPVIFLDHSGNESMKTKSRVNWDEAHIVASVVEDLLLNNDNLNGQDIGIIAPYVAQISLLTKLFNADPKYRDRFNTVLGEHRAMQLSNIEIKTVDGFEGREKEVIIFSTVRNNSGGYIGFLADRRRLNVGLTRAKRGLFVVGSMNTLRQGRTARSNDGATKVGKGAESWRRYMEYVGQHGLVLNLQPGDALAKVLHGNVNAAAAAAIAAVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VWH9</accession>
    <name>A0ABQ8VWH9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_892697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37487">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37487:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045912584" description="GPI anchored protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="18556" checksum="0AC17040AFA9F9E9" modified="2025-10-08" version="1">MNSFVLVVVVTFIAPSVLALTVNTPSSLTTCEPTLLSWSGGTAPYYLSILPGGETTSAALKTFDTTNATEYTWTVDIAADTEITVELKDSTGTIAYSDEVDITAGSDTSCVSTSVSASATAGSTSISADSSVTTTSGSSTTSANSASGSTSSSTSASSASSSSNAASRLMANCGTTGFLGLIGVVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX07</accession>
    <name>A0ABQ8VX07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_813058</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4500040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="7">
        <location>
            <begin position="10"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4500040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="361" mass="38861" checksum="C2FF5CD4187F8486" modified="2025-10-08" version="1">MTQVSNFGCVLIKALSVEVKEVTLPVVGPEDVMVKVESTGICGSDLHLYNHFGFGKVMMRKPNILGHESAGTVVEVGHNVTDVAIGDRVCIEPTMFCRKCHNCKIGKSNVCRNFRQAGMEPTPGTLQQYYVCESDFVVKIPDSLSWEEAGCIQPLAIAIQLAKRAKFAAGQTVAVFGCGPLGALVMATARAYGVSKIVAIDISQKRVDFAKSMWADYSFISPPKELPQDYPDWAAAFKDQVMKDAGLDPWGVDIAVEASGAEPCMHAGIAFTHPGGTYVQAGLGRAINSFPTVEVVAKELDVIGSVRYTAGCFQTAIDLVVSGKVDLKPLITAIFPLSRSTEALEAVRRGDDLKVVIMNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX38</accession>
    <name>A0ABQ8VX38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_429069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="452"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="658" mass="75360" checksum="E296F9A5952ED815" modified="2025-10-08" version="1">MSPPPPPPVFPIFLTPPAKESFPVVQSAHEHLRHASDTIHQHRYSLASQLKGFDSRWAHLFSVAPVLNKLTKGRQRPDEFRKNAQGLDDDVQVALEEARQRKHSQTRFADEQDSIIPGPPPSDTIYSKVSKKVKALSSILERVERGDQVQPGASRTSRSPHVSSKTSSQSKQSKSRAKSPTKSPSEQSKTRSSKLTVNQTSTRRPARVRKKDSRHSIRSIRSARSMTLRSSSPFRHPKPKRSSRDRLRTTSGRDGERERDPGRDRDYRHREDRDRYRDRNRDRDRDSRDRDKDRDRDRERDRYSRDRDRDRDRERGRNSREREASRERTRDTRRSPRSSSRHDHHHRYSPEGKTYSPGNLGNVGQPPVPAPPHPVLSAPPAPVIPSNMPPIYARFANGHKYEYENNADLEPLQPPVLPFVTERMEKRREAREQNGRSPQDQNQDYRRDNRGYPLSSSYPLPTSSYHPQNPQIIPPSDGRGRGRDRSSKSAHRRAGYNGYDNYTYSSTSTPVIPVMATLPDSSSVPINTNIVIPAPSSTRHLSRSRYPPPSSKASRSPYLHTREEYGYKNDHGYNGYNGYNGYNGYGRDGRTGAEYQGDGGHRYDSNSNVRNARSSRSPRTHYPPSPQPTRNPRSPKSPLIMRSKFKENFSVLQSESGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VXY7</accession>
    <name>A0ABQ8VXY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_876693</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF15">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="85"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="398"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4499375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="637" mass="70216" checksum="B8FDBF7DD9BBCC88" modified="2025-10-08" version="1">MAPSASKQKRLAEKAAKKAAGVGDASTSTSTPTGSVNGSTGVNTPMTSVSAATSSEDLTNMAKLKIATDRSASGVLVSDVKARDIKIDQYTLSFHGRLLIEGAEIALNYGQRYGLLGENGSGKSTFLQSIAERDIEIPQHIDIYLVRGEVEPSNVNAVEFIVASAKAKVEKLEKYIEELSVSDDPDAELALDAAYEELEELDPSTFETKAASILHGLGFGQEMMKKATKDMSGGWRMRVALARALFVKPHLLLLDEPTNHLDLGAVVWLEAYLSTYNHILVITSHSQDFMDSVCTNVMDLTFKKKLVYYTGNYTTYVRTKQENEVNQIKAYNKQQDEIQHIKKFIASAGTYANLVRQAKSKQKILDKMEAAGLVEKIEAPKQLSFNFEDVRKLPPPIIAFDEVAFSYSGKKADYLYQNLSFGIDMDSRIAILGANGAGKSTLLHLITGALQPVEGTVSKHTALKLAKYSQHSADQLPYDKSPIEYFQSLFSEKFPEKDTQAWRAQLGRFGLSGTHQVSPIKQLSDGLRNRVVFAQLAMEHPHILLLDEPTNHLDMESIDALAKAINEFEGGVVIVSHDFRLISQVAQELWEVSDKKIRNLTKDDISIVDYKKNLVKASNAAIEKAKLFSKTAPKGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYR7</accession>
    <name>A0ABQ8VYR7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_432531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="159"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="730"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="795"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="827"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="954" mass="103423" checksum="69737F46D0E489B1" modified="2025-10-08" version="1">MAFLNRRTTVMTTSSSNSGHPASSSASLGIPPSTGNSNNSLYSSQRGQSYSDSIMKRVSTMFTPKKKSSQDTSSVFGIGHEASNLSKQSRKKDKSSKSRRDSVRSFRASSESDLEDLEEIRQPNDLGPTRASSVPNLGSFIPATPPPFTLSVRRKPPPRLGLRELPVEIIAHVFKLLPRSLLLGLAPLSKNFSQAAQLVIYETLDLRNISSSRQDELDILLTKRQDLTEITRELICDDRPSLYLHSFPSALILAHMTHLTTLTLPSFSLDLMQHHTAFGLRSVTFFNTDLTSTEKVELLTWLDGQVNITTLSLPRLFDSPPAADLDNVGTLEREISHSPVLLSTSSPSRLNNHFSSPPSPLNSLLVSPQPSQIPLPPSPGLKSLSNSNLSSELITLCTSSTLLPHLGIVHAPPSILQLLAPSRARTLRKVGVNINDTLVGGLRPAELVGFLKASQGQPASSDESEDGGISEVNGGLEELYLNFGKNVDRRTVEKVLSAAGAALGGFSSSKAVERGRVREDKDVENSANSHNIQEDYHPPGLQSLEIAIPWNGPRTEEMLYKTIHSILPRYRALYTLVMRLSSPLPSNEITPSEPQVFSTTVKESLRPLLNQLPAVQVNGQPDADQTLIEDVKSDENDALLSPTDTNENSVDSEHSRVNQRHSYASSSQISLASGGTAPSAGSIVSLTMFPNPPSSLIPIPRTSTPTNNGTETALGSPKSAISFYSSSNRTSESPTLPSSPTPAKSKNFLGRLPSLKKRGKRADTDPLPPLPKITTQLTPSGRSATLPIPIPVSPVSPRTPTITTPTTITPTPPSTDIPVTMSTIPNTPTTPRMPSTPSTPRYSQFVQTQPRTAVSTTDRWDDDLPTQRWETRRVSSMTTSALSVSSSIRSVDWNHGNTNGNGSENSGPPSPRTPVPETPTIVLTDSEKKHVRMWIRQCPTLRRVVFISGAEWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYS7</accession>
    <name>A0ABQ8VYS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytidine deaminase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_913481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10540">
        <property type="entry name" value="SET_SpSet7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="16"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="312"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4501481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="471" mass="52616" checksum="2E5D9FA05C221D3C" modified="2025-10-08" version="1">MSVSSSSIAPEHLNSSGCRIQYSESKGRGVYASREIPRNTVIEISPVLFFGKKEYEKYGKYTVLDHYTFKWKDGRMALALGLGSLFNHSNSPNVSYTLDPCTDSIRYRTARNIDPDEELCIFYGHNLWFDPVDTTVSVINPELEDGWGGLSAAWNDHDDLGKLSNSVDQNEIVDDHSLPFTMLKPPPEEEDLATVRTEALHLVLAWVVDVPESRQITTLLKWLKNSGSEDPSLGHLKRIRKQDGKTTLLLSVDPTPPELPVELELASPFQIPVPSSAALTLTSLSLKATFWPTFYAPKRKGEVEHWSRGKVEWAREAMKVVETEALKSQSENELPISAFMPASYGGGEDEKVAVAHDTRTSNSHPLRHAVLNLIRRVADLEVDKSSSSENGFNYLLTGRSVFLSHEPCIMCSMALLHSRVKQIFYLNPMRRTGGCGGVTCLPTLQGVNHRFEVFLWKEVVSKLVINEALDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZ65</accession>
    <name>A0ABQ8VZ65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_813844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303:SF2">
        <property type="entry name" value="COA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303">
        <property type="entry name" value="CYTOPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA-binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="15879" checksum="49236B153C85B32A" modified="2025-10-08" version="1">MAFEAVKTAFFHSPAYAVVGASKDQTKYGTKVLQWYKAREMDVTPVHPKESELEGITAVKSIEELSSPSTTSISIITPSKITLALLQKAKELNVPALWIQPGASDRDCIQFIKDNDMVDRVIYGGSCVLTEGDSFRTNHNTSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZD2</accession>
    <name>A0ABQ8VZD2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="324" mass="36474" checksum="00CD834A70E9849F" modified="2025-10-08" version="1">MHPLPAQHPDATSESSLPYSQTSPPRFPSPVLGAPLTLRASPDNIGLNHLSDGALPVTDDHSANNGDLVPDGTFADVTAACHQLGFVLESVKYQRRQGRGVSFLNMLNNWTATSNFIVALGYDRNGGLESQKVTFKDGPQSFADLLVNKLGWEIRGYQKKRTLFQWAEEATLRKKWSLTKSQINTEAFRTWMQMCYIWHDPGFVRTHSRLDSHADDEKEQVVHIHAFTLIYQQSSPPAVRIHAFTLVYQQLSPPAVRIHAFTLVYQQSSPPAVRIHTFILVYQQSSPPAVRIHAFTLVYQQSSPPAIRIKRTVIETQIDSQSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W049</accession>
    <name>A0ABQ8W049_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trypsin-like serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_892481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4501282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="63746" checksum="A3FC337092CFC9EB" modified="2025-10-08" version="1">MLCLDLLYNPNISSAPLFCFLPPPQSSSLHNYQRFITVEVSIRTVRGPHASPTTNLDPLASLSSTLYQLKNLGTEDDIPSAALCVYKSGSAWPVRTGPEAQRIIREARGVHGHPIQPVWLELGQRVYKLLDEMGVRWTSIDPLAFAEAGKKSFSPLLLWIGVVPGSLQYKLANTAAEAVTKLISDAGFSGVEIGFRESIVTPSLAGPKMLSFDPFKDPISEFTKPFTPTLGLSIAPLNSPHYEGTGALTVGVLLLTCAHVARPPPDHCNPAPVNKTSNNPREYIIALGHSGYISALQSMMGAIGDLHHLNKDWQDILDRLGEAQEDESETTTQKREEHLNLAKKAWWKTEKINEFHTDVSKLWNLPNDRIIGEVVHFEPIAASVGPQKLPEDWALIALHENKFEWDKFKGNVVYIGGNLSSAEYGKIMFPTDDERTNYAYPKDGLLQVRGVIQLDDIYNPKHLDVNGEQCLLVVKNGLTTGTTIGRALGMESFTRVYKESKIEKTSIEFGVLSYGSTKGPFSAAGDSGSIVLDRNGDILGMLTGGAGTANRTDVTYVTPYAYLDKAIKKYFPDSSLYEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W097</accession>
    <name>A0ABQ8W097_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="679"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="719" mass="82580" checksum="17ADB085679EE91F" modified="2025-10-08" version="1">MSTNVIGRPSARQTEEMIMRQAFRSTVSRLWPHVLHKTECMAYAVSGITSFAFAVVAADLAPLGSPLSRDILDTLLSIRPREQMLFSLNHTMARYVGLFLGLRGTDLEQFTSPYNSRHLLNFREASLPTLVVKLDTACASHNMRRPICRLPPELISTIINLCLDLDPLTVPYSALGSLDQNWKLPISSKPPWYPFSRVCRVVRNAVLGDSKLWGKHVMVIHSQRSFQGIQSMVEFANRRLQAGKPVDLEFTVPDDKMREKLTLKAPESFGIPHTRMATMFNGFLHTRYLTISAPEEYLRELFSLKTPLWPSLERLSIEVQNPSECSLTVDDYNTPDITTFTNSPKLREVRLVSEAKQNSTPFIPRVALPCSHLTRLILRDGSDKFWPDLSIRIVFRSCAPTLEYCEIRSYGFLDDFYDSDSESNDEKEQLVTFPHLIDLFLDFGTGKHHRNYTTMSCVMLWNVAFPALKNFRLWTTVPPIYFNEEMNVGGDKSLDETMKILQQRSMFKLQKFQLFFAGWHAPGIASFLELIPSLEVLDLRGTYYGWTDTVRSISTRDDYLPNLRCVRVNDRTSFSPGWEEMEPSYGEHATLIRDMIPRRCIPVGKLETVVFNIRRPSPNNYISDGNGPMPRNFKRVIREIEKTRTSMPSEVRIHLERFPLGQYTDFSWSMPGFPPSWYEHQEAGKKTGQDTADSDEDTEMEPVEIPDLEFIPMEIDDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W264</accession>
    <name>A0ABQ8W264_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-glucuronidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_749510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047205976" description="Beta-glucuronidase C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="2">
        <location>
            <begin position="420"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="527" mass="55623" checksum="DDB77418B01EFF14" modified="2025-10-08" version="1">MLSTIILSYIVSVTFQACAINVFIPLTAPTNSSSISPSHISFSIEQDRWTDWPGATTKNEFVSNALNNLASLAGEPPRLRIGADSEDRTNFQPGLKLTETVFAPPSAATPYPEAESVVVGEAFYKAAQNLLPGTHVTWGVNFKALNLTAAFLEAGAIADAFTSFPASSGLSLDAIEIGNEADLYTNNGGRPANFTIAQYVTQWTSFASNVSLTVPIGPNTTTKFWGGAFAGSDHSSTGFSPQGLFANGILSSTPGNLINTISQHVYSGSGLGCGSISTCIQDLMSKAFVRGNLSQFIPDVAATQAQGLAYVLGETNSYFDHGTNVVGNVFSGAALWALDYALFASLLGIERLYFHEGVGYKYNFIQPVTLNLSIVDGTPLAEPLLPHIQPAYYGAIVTAEAIGKTGRVSELSINSDVVSGYAFYTNEGQLSKAVFVNSEGFFSNSGANRTSVHLDINFASTGQSPSHMSVKRLEIGHADDTDGLTWGGQTYETPNAQVSGTLSVITSDVGEGLDIPATQAVLLTFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9A8R2</accession>
    <name>A0A9W9A8R2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 1</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8J55DRAFT_516846</name>
        <name evidence="16" type="ORF">C8R41DRAFT_842292</name>
    </gene>
    <organism evidence="15 18">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JANVFS010000020">
        <property type="protein sequence ID" value="KAJ4476417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000060">
        <property type="protein sequence ID" value="KAJ4480778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9A8R2"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07835">
        <property type="entry name" value="STKc_CDK1_CdkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000281">
        <property type="entry name" value="Cyclin-dependent kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000027">
        <property type="entry name" value="Putative Cyclin-dependent kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="4"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4476417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ4480778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="294" mass="33640" checksum="67638B6AFAB58884" modified="2023-11-08" version="1">MDRYTKIEKVGEGTYGVVYKAKDNGTNQIVALKKIRLEAEDEGVPSTAIREISLLKELNDDHVVRLLDIIHVEQKLYLVFEFLDVDLKRYIDNGNQNRTPITPKIVKKFLWQLNAGLLYCHSHRILHRDLKPQNLLINKDDNLKLADFGLARAFGIPMRTYTHEIVTLWYRAPEVLLGGRHYSTAVDMWSVGCIFAEMALQGHPLFPGDSEIDQIFKIFKIMGTPNEQIWPGVSSLPDYKATFPQWSTKDLLGVVPVLDEAGIDMLKQTLIYDSAKRISAKRALIHPYFADYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W9AYX8</accession>
    <name>A0A9W9AYX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C8J55DRAFT_501285</name>
        <name evidence="19" type="ORF">C8R41DRAFT_893179</name>
    </gene>
    <organism evidence="18 21">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="18" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2</text>
            <dbReference type="Rhea" id="RHEA:23916"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="EC" id="4.1.1.35"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="6"/>
    <dbReference type="EMBL" id="JANVFS010000004">
        <property type="protein sequence ID" value="KAJ4492764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W9AYX8"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05230">
        <property type="entry name" value="UGD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000150">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="17">
        <location>
            <begin position="114"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ4492764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4499878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="433" mass="48876" checksum="613D0F2A6E57260D" modified="2023-11-08" version="1">MPSTSPVKVLDKSGQEIVSVGFDRFGFNSEVPIDALRSLYLRSHYVVTSTSDKVDGDSLDPDAEEQQHAKFTKGLSAYQSKSIFYPEDNSISYTTLARFPPVKLLAPSQRKRVLVTGGAGFVGSHLVDRLMLLGHDVTVLDNFFTGSRTTVSHWVGHPNFELVRHDVVEPFMIECDQIYHLACPASPPHYQFNPVKTVKTSFMGTLNMLGLAKRTKARFLISSTSEVYGDPEVHPQPEDYWGHVNPIGDRACYDEGKRVAETLTYGYQRQDGVDVRVARIFNTYGPRMNPYDGRVVSNFIVQALKGEDLTVYGDGTQTRSFQYIHDLIDGLICLMNSDESRPVNIGNGDEFTIGEFAELVREIVEKVQSEAGDRPSRRVQIIYKTLPNDDPQKRRPDTSRAKESLKWQPRWTVRMGLEEMVRYYKAKMAEGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWH7</accession>
    <name>A0ABQ8UWH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_898733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000151">
        <property type="protein sequence ID" value="KAJ4463899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="144" mass="15301" checksum="5E46C923C57DA098" modified="2025-10-08" version="1">MAPSEYSLRLQKGITGGFAPPTPSFIATITRPVDSDSLNITSASRPDGTPDLQSFAPKTLALGLIDELHGILKELPTEEPRGSEDIYGLDTSIFWGSDDLQWMNGGMGGVTGQPGSSTVQPTPEQKAQFKRAVEIVEALVGEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWX5</accession>
    <name>A0ABQ8UWX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_860181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000143">
        <property type="protein sequence ID" value="KAJ4464278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4464278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="50753" checksum="C80E129A38FB3686" modified="2025-10-08" version="1">MMIQDLAYAPVYPFNGLSSARCKRVSSELITLSVLNRQFRRISLPFLFAFVTLKHLEDVEKFLQMCLVNPTLGSTIRVIKLDEMHFSKKSGHDELCRLLPHLTRLTCVDLQGSTSSVTLLNTVNQHPSISTMIVDSLYGLDNLPPPLSSLNLSKVVVECGRISHPGLETSYVRGLEVYRLVVFQPESLKEEFGNSRFQGLHEISLVMNRHPLFLEWLPRLASSHPHLKKVIIADISNQKMKYTSDTIPFILPFIQKSSQQGLDTTFSITRLVITRALSCSLSTPEWRVTELDMNVQSSLLVILPLVASCFPYIHTLGVGVYHKRRYNVDELVAVLASFRSLRVLKSVRLFKKLRSPDEQLHRPWKPLRHIDKIHRVRRLGARAEARLYWYMSLISKALPSLEAVYIEEEGYGDEKSCSHGDWSLQGWLSIGGATRDVIGTLELSGTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXU0</accession>
    <name>A0ABQ8UXU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_926643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000129">
        <property type="protein sequence ID" value="KAJ4465212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="31"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4465212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="411" mass="45408" checksum="787EF4BFAD2CC10E" modified="2025-10-08" version="1">MSSELWQNVPLAPPDSIFKLTAAYKADTFDKKVNLGVGAYRDDDDKPWILPVVRKAEEILLNTPALDHEYLPITGLPEFTIAAAKLILGPDSSAIAEGRVTAVQTISGTGANHLGALFLSRFYQWSGDKKEVYLSDPTWANHPAIFNNVGIASLYYPYYDPKTIGLNFDGFLSSLESAPSGSVFLIHACAHNPTGVDPTRDQWDAIAKIMLDKGHYGFFDCAYQGFASGDLDNDAWAVRFFVDKGVNMLICQSFAKNAGLYGERVGALHVVSPNKEAAERVKSQLSVLQRSEISNPPSYGARIVTLILNDPALFDEWKRDISTMAGRIIDMRKELFKILTEELHTPGNWNHIVNQIGMFSFTGITPEQSKALTEKAHIYLTVNGRISMTGLNRHNIRYFATSLDAAVRGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZ13</accession>
    <name>A0ABQ8UZ13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Autophagy-related protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Autophagy-related E2-like conjugation enzyme ATG3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_857001</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000115">
        <property type="protein sequence ID" value="KAJ4466374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="301"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4466374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="369" mass="40722" checksum="CF6C7E25F6CF5FE9" modified="2025-10-08" version="1">MHAIQQQYWSIRDYLSPVLKESKFKEHGRITPEEFVAAGDFLAYKFPVWTWEKGDSSKARDYLPADKQYLVTRGVPCLRRATSLAYTDADEDAERLLNFGDSSAGGDGDEWVETHAGRKPNLDSAANPGEIADIPDDNAQDDDLASGVGNMSLGNVPAMSEIPDIDEIPDMEEEDLEEGDAATAPVKATPNVIDPSQVEVATGNLLQVRTYDVMITYDKYYQTPRIWLQGYDENRTPLTPSQIFQDVSADHALKTVTIEPFPHSSSLQAASVHPCKHASVMKKVIERMNNSVVAEQLAQQKIPKEKKKWPFGRKTSGTGKDDKNAAAAAAAAGDDEEVEGMRVDFYLVVFLKFIASIVPTIEVDSTTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZA9</accession>
    <name>A0ABQ8UZA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_925975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="286" mass="31538" checksum="A5CC53409AD77AF7" modified="2025-10-08" version="1">MSSADSENINYATIFGFNSVAAAAVFAALYTLLFCFYLFKVIRERRGILIALLAFCLFRIVGFIMRAIASNNTKIGENPGYVVATETFFSIGFFGLLFCAFLLVVARLELCATKPSTSPFIRTLLGFTRSPRVFRLCLLAPMALGIAGLDESVDNPQESLGLELRKASAALFLVLTFFQVVQTGVLIKSEYEDKNSLKYVSPSFGGRHASWIFGGISLLLLIREIFTTATINTFSRANNEHYWYPLVAVPEILCVILYMIPGVVPPKVRAKSDSSDVEESLPMGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZV6</accession>
    <name>A0ABQ8UZV6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_857755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000121">
        <property type="protein sequence ID" value="KAJ4465870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="13894" checksum="D31D2D4A22D9FCD8" modified="2025-10-08" version="1">MMAYTFFTVYQPRRNINIHISLLDTDTAMPHKFEDSAASSKFIKKDMQAKGLGHPTAVDKAPTGKDLYRSAPVYQDAPNDPPEPMETLKNPSSAGTDFKVGAAGTTGTLEVVRDAPMRNLPPEVLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZX7</accession>
    <name>A0ABQ8UZX7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_927307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000156">
        <property type="protein sequence ID" value="KAJ4463620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4463620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="42071" checksum="8CF55EA5A5DA68E8" modified="2025-10-08" version="1">MKKADWSAQDAVKALQRDNPTLYEHLHCGTVWKWKEKDARAWSEKTREKVKNHHALLGSGRAGALTKHPELVEEIKTTLSSLCTSGFVWENIPPKLVINGNQQGIFVLPSSSKTYNTKGDSDILPFQCVWAGKTAASLPSKDAPGMEKALGHGFCFTVAASEKSPRSHFSTLKTMKEYITDIIMPYVKSVIAADPDLNNEQKAVLYIDVYPVHTSKPFRTFVYTGFPNLVIVFVPANCTGKYEPANLAAGAKPEEIKVTTSLPKLRDASVAGLVKAYEYMQLLDGRDLIKKAWAKSTTSNGYNLSAECLTSRESHAALSKYLMMDQTLHHEIEAWCGKVLRLDDGTAVEGNTDFGCDQNEDADVPFDELVAETFSEQTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V004</accession>
    <name>A0ABQ8V004_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_857826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000122">
        <property type="protein sequence ID" value="KAJ4465746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047362382" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4465746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="185" mass="18313" checksum="AEDB5E2416473C0F" modified="2025-10-08" version="1">MRASLAAVALFPAYVLATISISAPSSSEFWVFNTSNPINWTSTGGDPTSFNIDIINLDNTTLNGAFSIASGVANNLSFEVTNVTLVPGDNYICQFVNSSNITQVFVNSSTFSVKPAGTTPAPPVSSSAASSSGSSGSASSGASGSSTASGSATSASPTSNGASSLFTTKSAVVAAGAMAFVALVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0F9</accession>
    <name>A0ABQ8V0F9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13455">
        <property type="entry name" value="MUG113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00974">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="1">
        <location>
            <begin position="103"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="202" mass="23694" checksum="AF4F4297CACD99AC" modified="2025-10-08" version="1">MLSNLTPEDWEVNVKRTVWKEDGWHRFGLKRYCLSRLCLGIALVWGKWVPEKLLTIHTQLEERVDIKRGACCFESRVNRRQIFLQRPARFYPSIRRCFLYAFVDGGVLWKIGMTKDFDRRRAEWDNQCPFPGRIWMAPVPTMTRRRAESLAHLALENSCLDRPRVWCNNCGRQHVEFFVFTGNPGQVWPTIISPILANAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0I6</accession>
    <name>A0ABQ8V0I6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">dihydroxy-acid dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C8R41DRAFT_778843</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14"/>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="entry name" value="IlvD/EDD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050165">
        <property type="entry name" value="DHAD_IlvD/Edd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
        <property type="entry name" value="ILV_EDD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002068">
        <property type="entry name" value="PRK00911.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000:SF5">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24877">
        <property type="entry name" value="ILV_EDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="IlvD/EDD N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase N-terminal" evidence="17">
        <location>
            <begin position="35"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal" evidence="18">
        <location>
            <begin position="373"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ4468060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="568" mass="60924" checksum="26846AF32138F9B7" modified="2025-10-08" version="1">MNRYSRVVTQPKDQGASQAMLYATDGISSDEDFNKAMIGVASIWYEGNPCNKHLLGLGQDIKLSLQKADLIGYQFGTVGVSDGISMGTRGMSFSLQSRDLIADQVETAAGGHHLDGMVVVPGCDKNMPGVLMALGRLNRPGLMVYGGTIRAGSCEGLPPLDLVSAFQSYGKFLQDGETPAAEKERYQTVRHACPGPGACGGMYTANTMASAAETMGMTLPGSSSFPAESQEKRAECASIGPAMYELVSRNILPREIMTRSAFENAMVLTMILGGSTNAVLHLIAIAHSVGITLTIDDFQNVSDRTPFLADIKPSGKYLMEDVYKIGGIPKILHFLMKQKMIDGNNMTVTGRTLGENLERWVHKYGELDFNRQDVIRPLNKPIKETGHIRILKGNLAPGGAVAKITGKEGLDFKGKARTFDSEDDFVKAVESGSIKKGEKTVVILRYLGPQGGPGMPEMLKPTSLIMGAGLGFDVACLTDGRFSGGSHGFCIGHVVPEAQVGGPIAFVQDGDVISVDAVKNTIELHITPEEMEKRRKAWVAPPLKVAQGTLYKYVKLVTDASHGCVTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0K8</accession>
    <name>A0ABQ8V0K8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_856602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000113">
        <property type="protein sequence ID" value="KAJ4466743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4466743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="81" mass="8863" checksum="3E1B1FE3F6DF35C5" modified="2025-10-08" version="1">MVSLLLFSLFSVLRSLFSILRPLFSLCPFSFHSSSFLPVLLPSVLVSCPMLYITPPLCSLIGPPPLPSPSSFLKILDSSHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0L4</accession>
    <name>A0ABQ8V0L4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_778911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4468086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="478" mass="52671" checksum="DEF0B64B88B7BC5C" modified="2025-10-08" version="1">MGLHIPSLFPSPRLRHSFDRLRSFHLVPGLGAAIPDNTTHATVGGTIFTEPARKERSLSLRAIQTPAIRTVNGVIPVPPIFYFGLAILCSVIFVLTIPSVFHGVTAQEPLFKSILDEVAHSNPGIVLLGESVDIDVDEPSVTIRWSIVACGQDYMLPGSSGIHGSTLCGLPNNTLQIYIDGDNDPTGVFDPELIPYSENGERRKIQNMVQFDSDHVLDVHNDRLYPFDTYFLSSTLRATSDKDYPISFSKLATIDLTSSFVVESADVQSFVLSADGVNAPSRDIDIHIRRPIEARLITLLLFASSWFLTHICIGNVILARRTIYVKSILKILIVNGATLIGLPQIRYSMPDEPGLDDAIGYFPQMIIVGFSVVVLLLTVIARELNDGERNALPQHTSMSLAPKFGTYQQSKTKHRPPPLPLPTSNSTEIARYNIYRMGKHLKGEFVFPPVRLEGLPEEAGSPRSPSHKRFKTTTGSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V133</accession>
    <name>A0ABQ8V133_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small RNA 2'-O-methyltransferase</fullName>
            <ecNumber evidence="11">2.1.1.386</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C8R41DRAFT_704505</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>small RNA 3'-end nucleotide + S-adenosyl-L-methionine = small RNA 3'-end 2'-O-methylnucleotide + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37887"/>
            <dbReference type="Rhea" id="RHEA-COMP:10415"/>
            <dbReference type="Rhea" id="RHEA-COMP:10416"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74896"/>
            <dbReference type="ChEBI" id="CHEBI:74898"/>
            <dbReference type="EC" id="2.1.1.386"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. HEN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.386" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026610">
        <property type="entry name" value="Hen1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21404">
        <property type="entry name" value="HEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21404:SF3">
        <property type="entry name" value="SMALL RNA 2'-O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ4467089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="248" mass="27889" checksum="2BA4E29A072ECEE0" modified="2025-10-08" version="1" fragment="single">IEHLPPTILPFFAPILLGVYKPKFLLITTPSYTFNALFTSPNSHPSVRLRTGYSDPTCRTDRIFRHDDHKFEWTPEEFHEYCKKEAVEWGYTVDVSDIGRAQDADEWGRDTEVGGASLVAIFTRIDVVDRDAIEEKARAVVQGMLPQLQQSSSSPSTTPPSTPPQSPELFSPIAHRCLTTFIHPAHASAQQPLPLHSIGDIVKSRMEDLRESFLRVEELWYEPEVAQACGGWIELLIAAVEQYDGSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1M4</accession>
    <name>A0ABQ8V1M4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_925076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000095">
        <property type="protein sequence ID" value="KAJ4469630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4469630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="293" mass="33084" checksum="6461F1071DEE4913" modified="2025-10-08" version="1">MKRSNRNTPGSSPGYRPASSSPYQPSSSSHATRNGRHQWYKLHSVRAREEADSGSPTPRSSGIRGQHKRKELSWAEDSQIQTYTYVDHMREFNARWNTATKSSKIIVSDNDSDSVTSGIESTTRHKFDRLANGDSQDPRTYRYDPGRYGSESYDLLDKGFREDLTASPKMENSLLLYPASPVPKNKQSAYTADSPVLKIENPVVNSAQEKQAYNATALLAINVELKRRLKDSEDELASVKAHVDELENKLHLWKEIFNRMGVISTSVADGSFEADKVLDSLNRHLISKYRETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V1Y3</accession>
    <name>A0ABQ8V1Y3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000139">
        <property type="protein sequence ID" value="KAJ4464579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="21012" checksum="18AD8541F5F4BDC2" modified="2025-10-08" version="1">MSFGSDPESFLVYALSLPDPVVPDPETSDSSDQSSPSEQHSEQESVQSSTNSDPDQSSYDSEFPGPFDYDYLYQSSDFDSDHPGPYDLSYLHSYPSSSASDSHESFHSFTSKASEAPELRPGDDRPGHPHLGPDGRLVDSERERHRVLGLCFYCGGEHMKVDCLKLQARTGENYDADDSELDIPGSDDGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2B4</accession>
    <name>A0ABQ8V2B4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate esterase family 16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_898537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000131">
        <property type="protein sequence ID" value="KAJ4465084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF85">
        <property type="entry name" value="A, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33605" checksum="866D87D6EBA6A380" modified="2025-10-08" version="1">MTVAATVATSSGVNWNSTRFVYAFGDSYTFVQGTSGYPNFSFIGDVLDLAFTPQKIFFDDIIPKNTSSEGSNWVQYLTGCFEGSPTLCEKQLWNFAFAGSDIDAALLPRHHNFTTSLVEQVAQWTEYASDVLPHPENETLTFWWIGINDTGDTMNNASILDFAAFWETEMTSYFSAVQMAFDNGLRKHLFINVPPEDRNPATVGNTTAAAEMKEHIALFNSALANHTIAFSERNPNATVMTFDANAVFNNILDNAAEFGFSNITGFCTCTDPEGFFWYNTGHPTQAVHKLVADTLRSQLESGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V2V2</accession>
    <name>A0ABQ8V2V2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_925961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000112">
        <property type="protein sequence ID" value="KAJ4466786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="675"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4466786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="936" mass="106986" checksum="4D747D968C97333D" modified="2025-10-08" version="1">MSLLRCQVPGCMRTFKRSSDLTRHVNLSHKHYGVDPSTPPDPRCPNSPEHDLFNDQQLYSPPPPPLPKERKNYHPFLRGDICTEDGRPLSASSSPPPQVESQNPWEPFSGEAQFRISNLLFKKVQMSQTNIDELFNIWNLHQQELTKTDSPFENHKDMYNVIDSIVDGGAAWNCFQTVVNEHLSPDAPEWQRTSYQVWYRNPATVIANILANPEFRHDFDPAPYVHINSNGQRRWADFMSGNWAWRHATQIYENDTTDCVDGAMLVPIILGADKTTVSVATGHVEYHPLYLSIGNISNAARRAHRNAVIPIGFLAIPKSDRKYDNDSNLRIFKKRLYHSSISAILQSLKPGMTIPVIRKCPDGHFRRLLYELAAFIADYPEQVYLSGIVSGWCGRCQGIFSDLDGPSSSDRRSRKIDQILREEYGGEGRTLWDNFGIDEHVIPFTEDFPRADIHEMLAPDLLHQVIKGSFKDSLVEWCLDYLTTTHGEARANEILDDIDRRLAAVPAFPGLRRFPHGRRFKRWTGDDSKALMKVFLPVVAEYLPEEMMRCLSSFLDFCYLIRRSDIDEQCLDAIKSSLEAFHHYRDIFKTSGVRNHFSLPRMHSMLHYPFTIMDFASSNGLCSSITESRHITAVKKPWRRSNRYKALSQMLLTNQRLDKLAALESTLVDRQLLLPSGRTQPSDPFDAENEDVGPTDSGHSLVDVKLAKTRETSYPRYLSELGTHINQPNLELLTRRFLHEQLDQSDSSSSISLSDTNIDSLPEITSKIDVFHSAVAVFFAPSDSSGIRGMRRERIRSTPSWYGQERRDCVLVVLNEDIAGFLGMSAARVLLFFSFQHRQTKYPCALVHWYNTYGEQKDAKTGLWIVRPAEWNPQCQQQDPRFAVVHLDALVRGVHLIPVYGSEPIPLGLDFQQSLDVFDSFYVNKYADHHANEILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V327</accession>
    <name>A0ABQ8V327_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SacI homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_850656</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000086">
        <property type="protein sequence ID" value="KAJ4471669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043573">
        <property type="entry name" value="Fig4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738:SF5">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="5">
        <location>
            <begin position="144"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4471669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="818" mass="94655" checksum="37CB67308A2398CA" modified="2025-10-08" version="1">MAQRSSSLNKFILYENKLRFYIIASNSSDSRHRIIKIDRSVQDELVIVEDDAEYTGKEMSAMLKMLDDGNKNMGGLGKAKVIFGVAGFIRFTAGWYMILLTKRSIVALLGGHYLYHCENTEMIPVCFNHKVDKPAEEQRMMNIFKQVDMSKNFYFSYTYDLTSTLQHNLAGSTRNVHGNWSFNDRFAWNFHMITAPFRDIEASRTHWLLPLVHGHVDQAKLTVLGRVIFITLIARRSRHFAGARYLKRGVNVEGNVANEVETEQIVFEALTTPFYYPARTDDDQCRRRPNPNYTSYVQYRGSIPFYWTQESNVMRPPIEISVADPFYTAAARHFDGLLKRYGSPITVLNLIKEQEPVPRESKLRDEYTQCVNYLNQFLPKDKQMNYVPWDMSKAYKSKNQDVISILEDLAETSIQQTGFFHSGPEPFYHYLQQEGEPPNDQLWRNKISLQNGICRTNCVDCLDRTNAAQFVFGKRALGHQLYALGVVENPNLAFDSDAVNMLTEMYHDHGDTIALQYTGSALVNRVETYRRMPHWNSHSRDIIENIRRFYTNSLLDADKQAAINIFLGITNDRPIALPPVRGGYRQWFDEEHLKPPYVIEDCDQKLRDFVRYRGDFWIEYYRPLLFTSLMKHFAYSMNSTLKLPGKTAKDMNYSPFETHGARSHHTGVVQGVKRWMSSNHPSAAKKANRKPTLQPEAHWKAMEPELDRHSTEAVAKQLLDPIVSEEEEAEYQGYIDQCQELLDARFDSGERKDLELYTTAVRTASGDNDFDWVDEEPREFITYVEHGSIQYLEGSGGRREALPVTYNYERWLSGAVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V476</accession>
    <name>A0ABQ8V476_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_926533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000126">
        <property type="protein sequence ID" value="KAJ4465462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045564">
        <property type="entry name" value="DUF5910"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19287">
        <property type="entry name" value="DUF5910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047127057" evidence="1">
        <location>
            <begin position="22"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4465462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="197" mass="22312" checksum="D546C07F3B0D6C90" modified="2025-10-08" version="1">MHISFNKLLLGFVLLLEGTFASPSIAKRMPKDLSKKVFLGYRAIDSITAASYNRKHRLVYTPTTFDQLGKGAYLTRRLGDWTADYVCAVYADATQLASTKKLWLDHDERESPVREQVIKTQLNMKEKNIHKVILTSGIWGEDDRESHVQMLIPPYLLAHKDSSGKLGIYVICVPWESHAELPTNEEADWSSLGIVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5A4</accession>
    <name>A0ABQ8V5A4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_774601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046497058" description="Integrase core domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase core" evidence="2">
        <location>
            <begin position="278"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="485" mass="55113" checksum="0B7510DCEDEDBFA3" modified="2025-10-08" version="1">MFQWIKLSLASFLLVFLLPGLAANTTHPTSSNGLLDAFRSHYEQFHALLVSVHSEETDPFLLRLLGEDLEEFSRIVNQNTNVFDLEELQTLLINPDFLSWAYSHRTTSGISQFLGISRATVRRRLLENNIALPGIDPFPSNADSSAYNRQPGSLEGSRTDEILDAQIEAPISLPEEIYAQAASIASTSSSATYLSSISDSQLDALLSQLRVHYCRAGIRMLDGMLRRVGHIVPYERIQHSLLRIDPIHRVFDRIRIRRRGYSVPGPNSLWHHDGHHRQSIHNVRIERLWVDVSHYISQTWHDLFTDLELHHGLDASNINHIWLLQYLFLPTINEHLAFWAEGWNNHRISQRNGPSRSPEDMFGFDMIANGMRGESLDEVAMTDEELEVFGLDWEGLRDETLLRSLRRNYCNEGSGSWLGQQGPPPELNRVVVDPLPGLFTPEQIAHMDEQLLGLGRGPQIEDVVHLWTTALAIARSMSSNDPTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5G0</accession>
    <name>A0ABQ8V5G0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GPR1/FUN34/yaaH family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_847095</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4475394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="239" mass="25016" checksum="C69959A921A3A704" modified="2025-10-08" version="1">MADLEKGTTTTTTSGVDHRPYADNGSAAYRNSPTTPVRTNIGNPGTLGLFSFASTTLILSLYNTSARGVNTPNVVVGMALFCGGLVQLLAGMWEFAKGNTFGATAFSSYGAFWLSYATILIPGSGISDAFTDVPSQEPNAIGIFLMTWMTVTFLLFIASLRKNIGFIALFFFLTFTFMCLGAGNFVVASAPNASAGLIKAGGALGIITALIAYYVGLSELLASERAAVVGLPIGVFKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5G3</accession>
    <name>A0ABQ8V5G3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_721155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000074">
        <property type="protein sequence ID" value="KAJ4475407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="319" mass="36158" checksum="DF735F39B2BA8E0A" modified="2025-10-08" version="1" fragment="single">LNAFIHSLLGYDATHQDIKGGILGLVKGYYGCIEAQGRGTLHCHMMIWLEGGLNPNEIRRRAIEDPNSDFCRRLIAFLDDTITNQLPVDDSVGIHVPSDDFHPCSVRGTTMVGYDAQDSNPEDAVRKDFHNLVQTCQIHKHTATCFKYCKGSQPKECRFGLHESNTTAETVFDENTGELTLRCLDGLVNNFNETILRAIRCNMDIKFIGSGASAKAVLYYITNYITKSQLKAHVAYAALERAVRRLDEQCSTDTPFTIRAKRLLQKCAYSMISQQELSAQQVNTYLLDLDDHFTSHQYKNFYWTQFEHLVECQIPSPEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V5Z6</accession>
    <name>A0ABQ8V5Z6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine protease inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_923481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14965" checksum="AA9FEE289B5DD599" modified="2025-10-08" version="1">MSLETGRYIIKNGDKIRIILASSDNESTWIIEKTDSVKDPSYLFISFGSPTTHIEHNVFALLVNQEAATKWVVIPVSKHGKDAFLITTADRNEGWVAPKEIGEQIQYRPLIIAPSEPPQFPTSEVFHITKVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6A6</accession>
    <name>A0ABQ8V6A6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_773631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000070">
        <property type="protein sequence ID" value="KAJ4476525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4476525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="51" mass="5889" checksum="6E0C6CCDBD9C4CE3" modified="2025-10-08" version="1" fragment="single">FYSFAHQSRRFMDAYHRGLSGKQAAWAGKMYHGHCVLPDSLMKDMEVANLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6G8</accession>
    <name>A0ABQ8V6G8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4475117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="176" mass="20147" checksum="96C8CD21ED2CAC64" modified="2025-10-08" version="1">MSSVHFASPPQVPEVDAEVVPKPKPIQKSRPQAPAYGIHGPLVLGFAFSFEELHKRAFERLPEYRELSQQSPQPDHKMMIRAHNFIYRLCADIDHLWPQAFKGWVRDPDTGNGMYVVRLSSNRDSDRLRMPTPAHAEKMQKILKCGQAQWYPDLIPPSKTNSRASVCPVFKLYVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6R9</accession>
    <name>A0ABQ8V6R9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:flavin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_911767</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF4">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="35"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4472644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="376" mass="41885" checksum="5738804B1414C6C3" modified="2025-10-08" version="1">MKFTNDGVRGVSGYFPYNDPEIGTPIKKTESMPLLFSPITIRNVTFKNRIFAAPMCQYSSDKGHATDWHLVHIGSMASRGVGAICMEATSVVPEGRISPEDAGLWTDSQMEPLKRIVNFVHAQGTKIGVQLAHAGRKASTYAPWVRERAGVRNTTVSIEENGWPNEVVGPSPIPWSEDLVEPKELNKDQLIGIEEAFIASIKRCQEIGFDFIEIHGAHGYLLSSFVSPLSNIRSDEFGGQLLENRLRWPLQLIKRCRDAWSKPLFVRISATDWADGPEQENDLVHVSSGGNWSNQKIIVVPYAESIKQANPQQLVGVVGVITDPKLAESYLQEGKADIIFLARALMRNPHWPLEAAEQLGLRVKAANQYERAFDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V6W0</accession>
    <name>A0ABQ8V6W0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Family A G protein-coupled receptor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_521042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000067">
        <property type="protein sequence ID" value="KAJ4477586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32100" checksum="E0E4E20A64D19D3E" modified="2025-10-08" version="1">MRAPSHGPPPLPPYGQLFIIGIWVESVLYGINIVVFTAVVVILLRRYQAGKSSARLLLATSTVLFLLSTAYVSISCRELLEAYVWGPPGGANLYFADASQHYTGVKLSLALVNIFIQDVILIWRMWVVYNNKWTIIILPILGEIGHVAAGISSIHSILLCKSTVSGPAVPSLVVYWGLDFVINIGVTGCIIHKLWSAGRTVKGFIITRDTHHPYLSVIFIIVESGGILAMATLITLCLYLSRNPAAAPAIDSVVQFATLTPLLIVVRVAFGLQRGVSVNETTAVSYSVELTQASPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V7G2</accession>
    <name>A0ABQ8V7G2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Association with the SNF1 complex (ASC) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_849603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000082">
        <property type="protein sequence ID" value="KAJ4472737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="3">
        <location>
            <begin position="551"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="325"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="627"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="72"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="630"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="676"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="699"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="798"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4472737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="887" mass="94898" checksum="608C27D11821180B" modified="2025-10-08" version="1">MGNSQSNQTQQPSSAYSPTGSRRFGSPRPRTSSAATAASSPKRSSSLRSATKPTRAQSPSSFTPPSNTRSGSTRVRSPQPQPSSSSSSSQYQQPTSPSPSSRVRSPIPIGSRLAPREREIRDAWEREIKEREAREVKEREKIAKEKEQFQPPYVHRSLQTKKKSLELPDLALTQVTTPTPSSASAAAPAIPIPERQPGAGYQYSTPIHIRSRSSSRPPDLPNPQSTAGPVAGHDYPRIVVRSSIPLPANLLIAEAKAAQATQAKLVLAESDSEEIINSIAVARSPSLLIPPISPPAHRVNPQPSEGEPTYLVKISWHGGGKEVFLTRAGDDDWNGRKKMEKEVEEQEDSEENSEKQTHESIIAGKGPTQVCHTGTTFSTIIALPRGTHHLRFLVDGQARVADDLPTAVDDNGSLANYVAVGLGSVGDAAAGDAAGDIASGDSPTTLVVAEGVDGAEVVAVAVDDVDVVVAQPEKTPRPGDDNISEFVVPDIHPHPTRVDSHSSFWSENEYTESHPPSLSSSPQTVISPLTSIDPNASATVNNLQTPIRIRKVPYAPRWTREIPLELLEAAADEESYLSYENELENAHAAGRRIHITGFVPLPNIPPAPRLPRYLDKLILNNPVVPPIARNGSPNTSGTTSPSGAAGATVGAGNDIGNGSDNNPAGIAGIGAGLGERTSRESRDSRTRDREGYPPLSPSREGRNGSRDGGRDGRDGSRDRRDGRNSRELREGRRREREWKSMSMVLAEGGEVDPAQGPNANANALESGEKSRGSERQRSNTLDRPLPITTASGTDVSHHPSASPSQPPTSISMMPAIPEPWGPSSHISNSNANAIPSIADDASVLPVPSHVVLHHLCTSAMRNGVLAVGETIRYRKKFVTTIYYKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V863</accession>
    <name>A0ABQ8V863_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Bifunctional purine biosynthesis protein ade10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_923502</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000072">
        <property type="protein sequence ID" value="KAJ4476169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024050">
        <property type="entry name" value="AICAR_Tfase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005492">
        <property type="entry name" value="PRK07106.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4476169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="600" mass="64580" checksum="582F2B1725420FC7" modified="2025-10-08" version="1">MSKPIALLSVYDKANLIEFAKGLDAAGIKLLGSGGTAKKIREAGIPIGDVSDITKAPEMLGGRVKTLHPAVHGGILSRNIPSDQEDLNAQNIEPISIVVCNLYPFTSTISQPNCTLADAVEEIDIGGVTLLRAAAKNHERVSVLSDPADYAEFLEAWNNGQGDVGKAIRNKLALKAFEMTAEYDDAISGYFREQYASGDLPKEKLAGPVQRIPLRYGANPHQKPAQAYVTGGVLPFKALRGSPGYINLLDALNSYALVKELQEALNLPAAASFKHVSPAGAAVGISLDETEKKVYGVDDLKESLTPLACAYARARGADRMSSFGDFIALSAPCDLATAKIISREVSDGIIAPGYSPEALDVLSKKKGGKYCVLEIDPSYEPPEVETKQVFGISLQQRRNNAKIDARLFDNIVTVEKELPSSAQTDLILATLALKYTQSNSVAYARNGAIIGLGAGQQSRIHCTRLAGGKADLWWLRHHPHVLALPFKKGVKRAEKANAIDLFVSGEILEGGEKEHWESLFEGPVQALTDAERKEWASKLEGVACSSDAFFPFPDNVHRAKKSGVKYLAAPSGSVMDAECIKAADEHGMVFAHTSLRLFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V8D7</accession>
    <name>A0ABQ8V8D7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_499101</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000062">
        <property type="protein sequence ID" value="KAJ4479883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="24"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="171"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4479883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="343" mass="37319" checksum="2A1B408C1D65B138" modified="2025-10-08" version="1">MEAVYYHGIRNFEILQTEIPLLNDNEILVKVSACGICGTDQHISEGEFIAKFPLIPGHEIVGTVVELGKEVDSGTLKVGDRCVVDPSLTCGLCFYCRRGQPLLCENYEGLGCTMSGGFAEYAVARENKVFKIHNLTDEDATLIEPAACAVHGADKLALPVGAEVLILGAGPTGLILAQLLKLNGASRIVIAANKGIKTNIARQLEVADDYIEIDRDSEDQDSQWAGIKDKYPYGFDAVVEATGSERIANLSIQYVRRGGTLMVYGVYANDSLVHWSPSFIFANEIKIIGSFAQMNCFPRAIAYLDSGKVKVSGMVTDTFTIKQYQQALEKLTSRTALKVVVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V9G2</accession>
    <name>A0ABQ8V9G2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_868962</name>
        <name evidence="3" type="ORF">C8R41DRAFT_951868</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000058">
        <property type="protein sequence ID" value="KAJ4481871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4481871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4492325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="162" mass="18211" checksum="BE88E25D47BBFBF5" modified="2025-10-08" version="1">MQISECNVSHPRKQCHSDQSNFKNTSPLRPATRKCATHAAHVIQCLYNSGVENSQVKSQTWVLSVYQHAGQSVLVDTASSNTQFLQSDNFEGRKGSLENLCAIDWVKVNKGGSTAEFAAHWNKIEKTLEAKVQSSTIIWDTTIKWDKRCFTMIYSYSGFGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA59</accession>
    <name>A0ABQ8VA59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_869593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="176" mass="19421" checksum="C5820CC86F01FBFB" modified="2025-10-08" version="1">MSGGGFEDPGPAACPRKSVRTKKRRRTDTYDYEDNTTSRFATGNMAAKPSKDVLVDLTTQLARISFGTQTTVGHIDYSSWVTNLKAIMEGTSDNVKDLAVSSLVNIAHRCDLASKVDGTAWFVRVKPMPRASIPPLGTPKIHLYCNLLLIVLSRYTYPFILVLPYCLLLYPAGLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA61</accession>
    <name>A0ABQ8VA61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Vacuolar fusion protein MON1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_840182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 3">Prevacuolar compartment membrane</location>
            <topology evidence="1 3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MON1/SAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000055">
        <property type="protein sequence ID" value="KAJ4484010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19038">
        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="5">
        <location>
            <begin position="179"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="6">
        <location>
            <begin position="344"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="7">
        <location>
            <begin position="576"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="510"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="541"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4484010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="718" mass="78222" checksum="054AC0426AA094F6" modified="2025-10-08" version="1">MMSGSSSRTPSISRASTPGPSNPSGAGYHRSPSKLAIAPVIRQSPSLSNLRVHSYNAGTPTDTNADVPPVPPIPPQLMSSGSHSSASSVINLELDNTNGNRILVQDVEAEVDSINEDVYQNKPGNESKEGESKKILRDQLRRTLTSNHATTEASFTNRGPARWLPDSQRSFHSKLSPREYFILTDAGKPVYISRGTDTDDIDVSSMLGVMQALISVFIDDGDKLKSINAGKTRITFLQRQPLYYACVSTWGEPESVARSQLEYLHLQILSVVTSVQLKRIFERRGNFDLRRLLGGADTFLTTMIARLQLDLAISMSALRCLRLDPFLRNKLAQALVPSGKFTKDILYIILVTQGEIITIVRPRKHSVHPADIHILLTTLASPSISNSPAAAMWVPLCLPKWNEGRMVNAYVVNIPYMLGGNSNSSRLEGTSGSSSLTSDPIVQCQDDLILPNSANNDSVVSTEAISVNRKRETQTLTSRSITLVCISGGSDFDSVRAWCDEAVEKLSASLPSSSSSVSTSNSSSMLSPSLSKATAPGTTLSASSSPANHTSSSSFHHLRTHISHSSYAISELGIPGLRHFVYKARGLVQVTYPVWEDEMYMARDTGGDINDKGKADEKNEGETDEKKRIITLYQLVHDAIHAKGMSNPGKGEVREGLKLQYLRTETEAVLGWITQPFELYLTLSPLLPKSAAVGAANAVARWVKKEEGKLFLKDAPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VA81</accession>
    <name>A0ABQ8VA81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_923157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000068">
        <property type="protein sequence ID" value="KAJ4477119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4477119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="355" mass="40800" checksum="3395119BEE0E1072" modified="2025-10-08" version="1">MTFFASATNFSINNGPGGNGPIFQHFRGDCHYIYHSSSVRQSRTTVSSRLQDSSRRHNEPLGNLPPTISNSRSERLGINRESNVHNHVVTYRLYEASSSPGTNGTSSPQPGHQTLRSNGRRQSQTRQDTSSWTELTSHDHSIDTERLEYYNVNVETPYRIHNAQDNRSSTSLRTRGNRISSYDQEREQYRRNRERYYLEREQYRQERERYHQERERGRVQRGQSRTLPNSSINGGVFNVVNGGIRSSGQEVFINRDHSNRLHHHLAEPWQNYYGNPDDYIQVDEDYIPPGMFEGNVQRDPEILYEAPAPSYTDSALDILLESGGRKTEEGGSSEAETPLYTEDDMDPISAYTTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VB48</accession>
    <name>A0ABQ8VB48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_740890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135:SF1">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4485087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="70" mass="8206" checksum="E2E1099791D8651F" modified="2025-10-08" version="1" fragment="single">MVLGPTARMLLPYLNFTIATSALAFQTTVLYPWHHELDTAFHTLRAEQLQVLKEFHEVKLGRIEELERRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VCK3</accession>
    <name>A0ABQ8VCK3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SCP2 sterol-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_884251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094:SF28">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094">
        <property type="entry name" value="STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4487473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="134" mass="14100" checksum="400B1B16D0CF706A" modified="2025-10-08" version="1">MADLKVAGFKSSELISSLGAVFESFSPAEKTSQIKKTNGVFEIVVKKPQGPSPTAQEAIWTIDLKKAGKVTKGKAPAGTKADVTITMDDETFVDLASGKLNGQKAFMSGKLKTRGNIMLATKLDGVLKGAKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD21</accession>
    <name>A0ABQ8VD21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="7">HIU hydrolase</shortName>
            <shortName evidence="7">HIUHase</shortName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_868438</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000051">
        <property type="protein sequence ID" value="KAJ4485170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023419">
        <property type="entry name" value="Transthyretin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00095">
        <property type="entry name" value="TR_THY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00769">
        <property type="entry name" value="TRANSTHYRETIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4485170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="125" mass="14277" checksum="2EAB9D006779776D" modified="2025-10-08" version="1">MKSPITCHVLDTSTGRPAQGVIIKLQQYEETEGDAFLFNPIAKGKTDFDGRCTDLLPPITSTETKDLLKPGLYKMIFRTKEYFDSQSVKTFYPWVEITFELSNLSEHYHIPLLISPYGFTTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD32</accession>
    <name>A0ABQ8VD32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_867862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="60"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4489055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="559" mass="62669" checksum="17DB81DD48AD85ED" modified="2025-10-08" version="1">MITFFLFHSSPGDSKGIRSSPTLEVDGCNSNSDSTGSALDYPHLYRPSRNPSMCISISTSKIIPSLPEDVLFMIFQHLSLQDVLSIRRVCRSFKDITHSRGLWVLILRKEVWDRDIPTPRFNLDHLSSAQIEKQVAISLHLHLNWTSKSPKVIRRRHVTVATPRARITSLHFITLGECSCLLSFSLKSRVEPRTVTIECWDLSSLRCKARRTVQWFGGYAVNSDPEMSFKLQGLIMQKVADFHSVEILAFDPSASSADLALIPLITLNTAAKSILSFSGTTVIFRTPNDELKILDIIRPFYEIKLEDRQPFVPPNQPDSFEAVLDNEYAIILRPKTLALYSLGTFRRGSHPPSASLSPSQVHEFQWRIDSCVMQRQISPSAPYLSNDSKPSTLNILIRYSSLFPWPVNLLHHYTLYPNDSYISSATNKHSSTTTGFAITSNNLPYKFPPVLSQTIVSPVRLFAITDMALGPYGTAVWFDSHTDYHGEVGQRLAGLMLDREETGSNNITAADQVSTMPSMVFGAHEKDDWNRLAIDEGEGCIAVGSTTGEIIIEDYAERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VD91</accession>
    <name>A0ABQ8VD91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_835570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045356699" evidence="1">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="178" mass="19107" checksum="CC35F3EE2937A438" modified="2025-10-08" version="1">MRFNAIRAYLALSIVSAVYAAPLSEADAGITRLARSDLSSVSHARRDGGEYVATFTLTKSGGGRGRGPVRSPKAKAATPSHIARVKALIIRAAKKKWDQDIDPSEIVIVGNQYSSNTDAVPFTLEAPSLKECNPLPCKGEALYHVFNANNKPELGAGTISSQLPPKIIYDSANKIWKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDB9</accession>
    <name>A0ABQ8VDB9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_867911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000045">
        <property type="protein sequence ID" value="KAJ4489121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="199" mass="22577" checksum="13EF922432922371" modified="2025-10-08" version="1">MTSTIVIAAQMLSTSCDLDERLESRNIFRKLLPETREQKLAFTSSNLDNMTKVLEAVRDLVIQSGTTAHKNEFHSLCQLCRKHNVELEKLERRIEEKGQSWANILRWDDNIGFLLKQLRDQVTIDKRVVIRASMKYRAELIDAGMVTITIEESPEVSQSSVSDTTTPMLNSNSSNQRDSSKSKIPTAIDIEMTNLSTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDS7</accession>
    <name>A0ABQ8VDS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Di-copper centre-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_766804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5046538355" evidence="3">
        <location>
            <begin position="20"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4489763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="367" mass="40428" checksum="E24725A1D3273ACF" modified="2025-10-08" version="1">MGFISTLGVLLSGALLVVSNDTQCTNPTVRREWRTLSRDERAAWISAVKCLAANPHNPDLIATVNSSISQIPAMNTSASFWDDISYMHMDLNVKIHQTGMFLPFHRWFVHSVEQAMIDKCGFSGGFPYWNWTIDAPDFYTSSWWQDSDPESGIGGWGDPDKDYEVQDGAFAGFPLAYPSYHPLRHQYTAQPFAAFAASSPTIAQFFNSTMLETFANSTFHTDQIAAIIAGNPGDYVGFQQSLDNWIGAHGSVHAITGGDLAGTCPATTDDCIPGNKWSPNSPLFFLHHAMIDKIWSDWQNLNGTSATAFYGGSVQAFDNTTYFAEYPNGALPMLNTSSQIYTDNMFPGGTIGDVMNHTAGYLCYVYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VDW8</accession>
    <name>A0ABQ8VDW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_834593</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000043">
        <property type="protein sequence ID" value="KAJ4489805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="11"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4489805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="532" mass="59462" checksum="46E430540E5921A0" modified="2025-10-08" version="1">MTVKYPKVAGYDLVQQIGGGGFSTVFRAVNLSEHRVAACKVILITDQTTEKDRKTIDKETRIHSVLKHVYVLELICAVTVELKYREMYVPGIYMLLELAAGGDLFDKIAPDVGVGDEVAHLYFNQLLAGMEYIHSKGICHRDLKPENLLLDIAGNLKVSDFGLSAVFRLGNGKTRLLSERCGSLPYVAPELNTDETYAAEPIDMWGIGVILFTLLAGNTPWDEPTRHSPEFRKYKSGDIFKEDPWNRLSEDALCEQSQVSLLFFLKLHPSLFLPKYSLLLCLLLLPIALLRALLTINPKQRLTLPETMQHPWCIRTSQLARQSTAVLADKLTESLRATGDMDYVMPQPTDLPMDVDQDDGDKETSSAAGPSHNSQFTQSLMLFSQTQSGARYTPHLTRFYARLGPALLMPIVKETLGELGIVFKESSSNHRSNVGQALDSSNEENTGGAIVGDGTIRENNGVDRIWKIRVGGKDARKILFKGWIEMEHFSHGGMNGTFCVMSRDEGNPLSWRQFFKALLKSDAVYPHVLRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VE85</accession>
    <name>A0ABQ8VE85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G protein-coupled receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_392173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000044">
        <property type="protein sequence ID" value="KAJ4489233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4489233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26664" checksum="3BE373F11E8B2763" modified="2025-10-08" version="1">MMAVTTVKAELGGTVIDCLVYVLLNRKIYDRTSLFLMSTTVALFCLITSHLALDVDRAFRAFTSNIGTPNYPKDYFNILSGAEALAKNSAYVTITLIADAFLTFRCWAAFGQNYLVIIIPSALYIGNLATACWALVTFKEAEDPTTGVVVVAEVISRVKYMYITTLCLNLYCSLAIATRIWFVQRQSTGTSGHLLRNTMTIITESAALYSVFLIILITSAALENPLMYAVLNPMPSIIGFVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEB0</accession>
    <name>A0ABQ8VEB0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Clavaminate synthase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_795969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000042">
        <property type="protein sequence ID" value="KAJ4491113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF25">
        <property type="entry name" value="OXIDOREDUCTASE AIM17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="8">
        <location>
            <begin position="44"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="172"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4491113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="51775" checksum="B09308566099D61B" modified="2025-10-08" version="1">MSSSFYRLATGKNSRLLPRRIIHNQILVSPALHRCITTATLNDNSLTIPSLDNATFPYIWLRDSCSSPECKHPETTQKLHSSTDFDVDIRPKTVNIIENYESEGGLGIRIEWPDGHVSFFPESFLKRHSSKEYLGSFRKDVEAETWDKEDIEQSRDLYLSHEEIKTPAGLLRAIDKLCRHGMLFLKGVSTSTPTEPTLTDLALQFSSEIRETFYGRIFHVQNTNAENIAYTNLKLGLHMDLLYFEHPPRYQILHCIRNRVQGGSSIFSDSFHAAKMLKSFYPEDYDILTKTPVPFEYLYGDHHLHFSHPTIEEDHYNPALQCPPIKCINYGPPFQAPLLLSPTSSSSLSPSSSSSALRRFYLALGRFAKLLDSPENTYEYTLQEGDAVIFDNRRVLHSRTAFMDPNAMDSGRSDFDTTEKKDISRWLQGCYFEGDIMKDRGRVLRAKKIAGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VEX4</accession>
    <name>A0ABQ8VEX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_920184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="Adhesin YadA, collagen-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4491813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="256" mass="27151" checksum="4D572A103FFE036B" modified="2025-10-08" version="1">MSKKALVDIAFSLKVPSKDATQDALCVRLHAHFDAHPELKKHPRYIGLFERTRKRKDPPNDAHPGPSSCRLLPPFQRSPSPEPSSFSLGPSSFSPGPSSFSPGPSLFAPGPSSFAPGPSSFAPGPSSFALGPSSSSTPGPSSALGPSSFAPGPPSFAPGPSSYSLSTYHSSLSSPPFFGQLQRMPLPLHAHHYHPVASENQSPSTSHQSTTPIYSVPPPLPHSSSSPPTTFSSSVLQPRPRPRPRSVPRRNVDYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VF72</accession>
    <name>A0ABQ8VF72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Transfer RNA methyltransferase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TRM8</name>
        <name evidence="11" type="ORF">C8R41DRAFT_920997</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with TRM82.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="9"/>
    <dbReference type="EMBL" id="JANVFT010000047">
        <property type="protein sequence ID" value="KAJ4487465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03055">
        <property type="entry name" value="tRNA_methyltr_TrmB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025763">
        <property type="entry name" value="Trm8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF16">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="94"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="131"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="232"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4487465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="258" mass="29430" checksum="5235993A5E9BB84C" modified="2025-10-08" version="1">MGKRKRVAVDQTAQDEGQKLLPQKRFYRQRAHANPFSDHTLDYPKSPQHMDWNAHYPGAAPGKRPEFADIGCGFGGLSMTLAPLFPDSLILGMEIRVQVSQYVQDRITALRTANHGDPTAHYQNVSIVRANAMKFLPNYFAKASLSALFFLFPDPHFKARKHKARIISPTLLAEYAFILRPGGIVYTITDVKDLHDWMRTHLENFPLFDFVSEEQLRAEGKGDIVDAVYTSTEEGKKVERNKGEKWLACFRRIEVPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VFR8</accession>
    <name>A0ABQ8VFR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_765022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000037">
        <property type="protein sequence ID" value="KAJ4492484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="206" mass="23212" checksum="AB939CCF7F865F38" modified="2025-10-08" version="1">MSHYVNPLHPSVHAGNTSSYSTLGSANHMSSPAASTFLIPNRRRLAQTPYSPSGKWKSTSGRMQPLHNPIAFDLKGYSKQGFPMQELCIRGEYALEQMMQGATDQVLAHAPYLRKITIHIRWPGYEHTEWARPIEVVTSRGPISRATLAQAIALNFARFCEKAQMERPQSPHWRIGHGGITFERLVLVSLWNPFEDAWQADVAVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VGD1</accession>
    <name>A0ABQ8VGD1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_325918</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF6">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="5">
        <location>
            <begin position="87"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="6">
        <location>
            <begin position="714"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="774"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="782"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="797"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4493311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="901" mass="100615" checksum="6990F622CAB0D4F2" modified="2025-10-08" version="1">MPPVPSISPATGKPTTSSFIHTLDSNFVDNAGRTLLLRGVNLSGSSKAPVDQPSYISDNFWESAEHGGKTFIGRPLDLDDGSADVHLARLRGWGFNMLRFPITWEALEHEGPGTYDYEFMDYTVRVLRKCKEYGFKVYIDPHQDTWSRFSGGSGAPFWTLAACGINPRNFTSTQAAIIHSEYPIPSAATPASLPAMVWSTNYGRLLSQTIFTLFFAGRDFAPKCIIDGKNIQDYLQEHYIEAMGQMADRIRDAGDLLEECVIGWDSMNEPFEGFCGWEDLNANPTKQGSTLKKGSSPTPAQSFRLGMGTAQTVDNWNFGTFGPSKNGSVTIDPNGDKMWADPDIEDTDGIHPRWGWQRDSGWKLGTCIWAQHGVWDLETGDILRPDYFRYLPKARKPIDRYALSEEEISSPNAPVVEFVEHYWRSHWRLFVIRIRASHPEAIMFIQPPVFAAPPPIEETGVDGLNGRCAFAGHYYDGLTLITRHWNWFNADALGVIRGRYSSPIQAVKIGERAIRKSLQEQLGILKSDTLTLGPYPTIIGEIGTPFDMDDKRSYGWTDDGKYRGDYSRQERALDASLNGADGSNAINYTIWTYCPDSTHQWGDGWNMEDLSLWSADDIGLTGRTPTIGDLLKQQGDEASMYGMGRDDSQAVLLKKKVEASQGRIFRQPSAADSSALSLATLGPLEVWSEITSRWRENPFDFLTDGARAVKAFARPWPTKVVGKPSNIQFDIASTSFKLTVLVRPEDKLNEEGIDDKDLATEVYVPLVHYAHPRLLPSREDEQPPSEDDTLDGGEVRIAPSPSEISTSTTPTITNASVGWEGLTEQPDVLDIEVTVSAGRWSVQGQTIKWWYEVPQVGEVDREYTMEIRRTGGAIKTNESLNYESWFEQLCPDLCPESCCVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH29</accession>
    <name>A0ABQ8VH29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_919995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000038">
        <property type="protein sequence ID" value="KAJ4492441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4492441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="510" mass="56647" checksum="77619ED52793261D" modified="2025-10-08" version="1">MAPREFQLQSIGFLRHFSPSVDLNNVDPDFVALERAFESGAAFGEQPPSGTRGGGQPVSATEEDSTPFSESSDEDLGLNPAPSRKHGAKASPRNQRKPGSKILHADDSATPRTSASPRQHRTALVTHSPPYSPDLSPDLALFPHKWKRTRKHQLRKWSLAKKAEKATKVHPTKASFEIKGDSRISKPAWMGLRASVDLRKPIEEAVSHPGSNLALELFKDLTRAPYLPHLALAVVDGLGRLFLYRSRLTPMMMADLLPKVNALVPDFVSAITRPFSNNDMLLNSRGEHWFSIAGHDRNNKSKPAATQFQQQNHQVIAGFFTKGSVLERLTAYGCDILKAHFPVIAQRYQDSIDYMLEAYGIQAMFDLTSIGKTWLLGCHFNHHEKCWLVIWEAGIVVELPPGVFLFYPSSLFLHFNIDVSDLPVFTTQHGETPTRENSTPLSFCSCNSHKGNRGWEDADGRGSMVWFNQASMIQTSELGVPTIEYARGLGMNTKCDGEGWFTKGAFPVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VH35</accession>
    <name>A0ABQ8VH35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_323447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000034">
        <property type="protein sequence ID" value="KAJ4494240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4494240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="112" mass="12115" checksum="E51E4F4E96942623" modified="2025-10-08" version="1">MKNLQSEIMSTRTANVTASSSSPLPSHFNPFATHPFTSCSAVSSASRPTSQPQPQLSTSTQPRLTHHPSPTRTTASPKAVFVPFRQGAASPDLYEILKKKPQPTQITSLKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHG1</accession>
    <name>A0ABQ8VHG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_763936</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000033">
        <property type="protein sequence ID" value="KAJ4494383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="69"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="306"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4494383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="39757" checksum="87F6B2878312E67C" modified="2025-10-08" version="1">MKRPLYESSTQYKNWRYSPERLSQIRSTMNEAAVGVIRKTFEAYEPGSSSNVSFVNAHEEHLLVTFYVHKISQLCGHFRFPEEVEATATSYLKRFYLKNTVMDWHPKSVMLTALFLATKTTNNPISLDVYASHIPNTVASDVLNLEFLVAQSLAFEFAVWHTHRALWGIWLDIQNLPDSPPDISKTQGSIYDSALIHVRAARLTDAEFIYTPSQIALACISLTAPDLAKKWLESKENMPVPENRTDIPPRPSATTLFASIEAIKSIITNAGKVPDVEAVREVDRRLRTCKNPEKVVGTKAYLARKAEAEKKAEEKKNKKAEIQKATGAADTDPFGDPLSEPVKPGLVDYDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VHV8</accession>
    <name>A0ABQ8VHV8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_763387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000032">
        <property type="protein sequence ID" value="KAJ4494506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4494506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="35722" checksum="706FAF9E76000875" modified="2025-10-08" version="1">MIARNLSDACPTLSTSLSNKSVELPTDIVREIFETTARNFPRTGAKLAGLCKRTQYWMEWIIYETVVLDHPPTRTSAFLRTIDARPAEFFYQRVKNLYLSYTLTLDEAQKILSVCSGLTHLTCWAQSSQRPGWLLPLLSSSTLTRLSIKLDMLKPRGPLFMFSDKIFQGLTHLEIVCPPPVNTGMSVDWTALMELPKLKHFIIGNLFSRDHFYLLPIIRGLLDAPASLEVLAILSKDPQMLEALDCQEFNDPRLVIFPRFNWPLDLPTYWKNLYIGELDAWEPSAQKGMKQRLERSQRVRRELIHYYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI12</accession>
    <name>A0ABQ8VI12_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_833754</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000041">
        <property type="protein sequence ID" value="KAJ4491698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF25">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="35"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="426" mass="47309" checksum="07D14A015546EB78" modified="2025-10-08" version="1">MFAKAFTPNFYLEPVDNELQLRIGTPSPAAPKEKRILVIGGGVSGMTSAWALMDQGYDVTILSDRWADRKNRITSQIAGALWEYPPAVCGKHTDAISLCHSKGWAMTSYKIFEQIVTKLGETDGIDHGVRMRIANFFFDTPLEARPDQLEKWEEICSLSHTIKGLKRSADLIQHHSVDQKAGMKDAYQLLSPAVDTDVYMMWLHFVLSCKGATFVTERIKGSLLDQEEELLSRFDAYAIINATGLSALELAGDETVYPLRGAIIRVKNDGTKFPKLTEALAVTHDETYGTDEDMVFIVPRNDNILILGGITEPNEWNLNLTVDTPVIKRMRERCNAFVPGLENAEYDDETDLLQGLRPFRGSNVRVERETAPRKDGSHSRIVHTYGQGGSGFSLSFGCAGTVVSLVQEIEASKPPAKMELVNAVCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2025-10-08" version="1" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI20</accession>
    <name>A0ABQ8VI20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_345301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000039">
        <property type="protein sequence ID" value="KAJ4492265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4492265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="783" mass="89767" checksum="FCAC7AAB4218A607" modified="2025-10-08" version="1">MDIFASFPEVEDATLGSKFLHAYLNKAPKGLFEPSVELCAAGLTVDPALHSTLKAAHRTRDLDALERLRTHLEWNSWRYHPQFSEMNEVILVTESAGKIEEMAVKELERPIWMPRKPNTNSQVAEFIRNLRIPLGSYKDVPLVILVKLGSFQYDRLLRKRLDRIFSPLNHTFLVNTSGTGKTRLLFEGLCLHWGFYITCILDSSLLGAGDFPHIVNNVNRNSRWNPVLPPISDPEHASALQGNVHLAYRACSEALLARLLVFKMYLKACSKVGFSHDQRRRWLESQIFPFDLTSDFDPFGKIRYSISILRLSDSILDEAISCTLKDIQSIWDLPPGEYIYITLDEANAASKKHRRAFSDEYGRYPILKEMLRALRRRMGHLPVKFVVAGTMIPPEHFQSAAGEWDDFRWCSDTGSFDDPEEHRRYVSQFLPSEFVSSMTGQALLERSWRWLRGRHRYTASYITVLLDSSFESPHTLLGNYIEKISNYIPHDNSEYTHGEVVRFNRWYTSIGDSGLKEGWISTIEMHRAIISFLVTSKGCIDCSTKERALVSEDYGYFIDSDCSRIVLDEPLTIMYGAGWFKQTKMVYTITTFDTFRFQHGIDIRASHFAFFLALSFASMFDGLSEVSDAFTISGISMPFPKAKLVTFTNIGPRLEARDAHFTDHTPDRLVLLATTMEDALCWFKHERDEPFCVLQDSSSTSVTLVFCLQFSDARTAWVSVRVPSTFQNAEDQDFARDIQDLHPSAIFRDQVRKTIQPQISQHISPCSSIWFRSSTKYRMSVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VI95</accession>
    <name>A0ABQ8VI95_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_866451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="312"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="402"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="748"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="810"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1037"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="756"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="820"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="850"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="864"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1037"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1084" mass="116107" checksum="CB4AAA163252FB1A" modified="2025-10-08" version="1">MSATPSPALADRLHDTSCHSRQTSHQSSADSTASIQSLHLASVPLSDFSTSRVPVSPPSHLATSPHPSSDATSYRVYRHDPNMVDGSDGSTLGTGEVVGLMRTINLTSSPTTSIIPERDLEEGEILASPASPKSPVGRAPRQREESFGGALPSSPEVLPSAASGRLVASLAPASSSGATSPAVINALSSLPTSSTLSSILSSSSFHTASSSSSIPTSISNSGSANNLSMCNSDSQDFNSGTKFTAQKPQLTSRSGNVPETGPIDLEALEKDSANATLTFNVNHSVPAHILSSDSDHGTGGSYDAADDQQKSPNVYINGLPSHFPEEQLFELAAPFGEIRSVRSFTRHVGEKESGYGFVLFETVEAAEKCIQSLRRFRNLHPTFSKQSHKIPGLPYTQSSLQSGWTHENDNGPSLAHGTGVRSSAAGGGTGMNQAGEISFKTKMEHLQDPNSTNLYIEGLPLSIDEPSLVALVSPHRIKSSRFFQTRLSNPPRIIAFVRHGAEEVVERLHGRMVRGWNDPGSRISVRFADTSEQRELRRSERVIREDDSASPARLTIAQAALLNLRGRDQLRNQQQTGVNAPLIGASRLVHGSAPTANQVYNDFSSNAHDLSAAAAGAYRGSASDLTSAAQLLAGLNNGPRRGVNLSPYHQTSPLPNVLGQTNQDLTPAMAALLDSLRGNGAPWTGHDDRYTAPQRQPHTFRNAHSVLGDVDLNLTFTPEYQSRVGGGVAQTRSGYTPAEELILNAHAQRRKSAHIGGDEPPYHQHGQHGDDAGFNVGVRGYRTQASTMAIQQQPSSYYLSSGNLPVVVESDGDQEAEHPPQSTRYPQSQLNGRSRQVRNSGPRERDIHNNFLSNNHNQQAHVRSTTLPPSSTPSAAAPRHYQHNSMSVLKSRNITNDIMRTTPSQLQTISSNQPQAHSKHRSMNSISSSILNNSKIHDDNIHNNTHLYSDASDIRTPNGGSSYTDMTSTHQQHHYRHNYPTKTAGDQDPPFGNNNLGSKKNGFDDGSYSVTTHSYTRNPETYDVPQTSPPLVSPALTYSSRGSGATLSPSTPYVGTFTSASGHGAGGEYQSAQGVETEVGAGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJP6</accession>
    <name>A0ABQ8VJP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_946725</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Self-assembles to form functional amyloid fibrils called rodlets. Self-assembly into fibrillar rodlets occurs spontaneously at hydrophobic:hydrophilic interfaces and the rodlets further associate laterally to form amphipathic monolayers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Secreted</location>
            <location evidence="1 8">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000027">
        <property type="protein sequence ID" value="KAJ4496603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044960515" description="Hydrophobin" evidence="8">
        <location>
            <begin position="23"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4496603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="134" mass="13378" checksum="0FEDA39E2D8EDA6C" modified="2025-10-08" version="1">MFFRIATVAFYALFAFAILAAAIPGGKPTTTIAPVTTTITVTAPAMTTTITSGDCTTGPIQCCESTESASSTAASLLLSLLGIVLNDLNVLLGLNCSPITVIGASGSSCSAQTVCCEDNAVGGLISIGCIPIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VJT3</accession>
    <name>A0ABQ8VJT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_866976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000035">
        <property type="protein sequence ID" value="KAJ4493316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4493316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="153" mass="16618" checksum="0D5F0610AC54F571" modified="2025-10-08" version="1">MAGNSVRRRGRPPGTIKRSQDKSPEVIISDDEDNVDKDAGQAAGSNLSSASSDLSSLQDSDFELPENPLDATPQLLKAPDELIKNSAAKRKNISEKDSSNTKDMDIDEERQTEPHKRAKTNKETTAVIAKTKPPPAPVKIDFVISLQKIGPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VK53</accession>
    <name>A0ABQ8VK53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tom7-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_760889</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000025">
        <property type="protein sequence ID" value="KAJ4496776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012621">
        <property type="entry name" value="Tom7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08038">
        <property type="entry name" value="Tom7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4496776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7512" checksum="1B487F0372DB52C6" modified="2025-10-08" version="1">MPSEDTKERIAKVVDVTRTFLHYAWIPMIIYVGFTRSNPQPSLIKCVAISIFSEYDFTNYYTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VKR1</accession>
    <name>A0ABQ8VKR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-hexosaminidase</fullName>
            <ecNumber evidence="7">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_824273</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="7"/>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06562">
        <property type="entry name" value="GH20_HexA_HexB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF26">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001093">
        <property type="entry name" value="B-hxosamndse_ab_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045160660" description="Beta-hexosaminidase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="10">
        <location>
            <begin position="18"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="9">
        <location>
            <begin position="176"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4496987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="553" mass="59849" checksum="C7879606860ABFC8" modified="2025-10-08" version="1">MTRRFLVVATVISAAYALWPLPTDFSTGTAALTLASDFDIDISTIPNPPQDLLDAISRTKGYLQTDQLEALVVDRGASYNQSLQNASSLVSLVLSYDSGVAGEPTSISEEAIDDIDSRVEGYTLTVPEDGSAATIKANSTLGLFRGLTTFGQLWYDLNNTTYTVEAPIAITDSPVFPYRGFMLDTARNYFPVSDILRTLDAMSWVKMTTFHWHMVDSQSFPLEVPEFPELSLNGAYGPSLVYSTNDVQTIVSYANARGIDVLPEIDTPGHTAIIAQAYPEHVACPGATPWATYANEPPAGQLRFANANTTNFTASLISSVSARFPGKYFSTGGDELNTECYAVDESTQADLNTTGKTLEQALDTFTQTVQSVLEDSGKTPVVWEEMVLDFNLTLSNNTIVMVWISSADAAAVADKGFRLVQAPSDYFYLDCGAGGWVGANPSGNSWCDPFKTWQYAYSFDPVANLTDAQAKLVIGGEHLLWTEQSHASNLDSIVWPRAAASAELFWSGPGGNISEALPRLHDVAFRMTQRGVGAIALQPLWCALRPGVCDLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VL18</accession>
    <name>A0ABQ8VL18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_760757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000024">
        <property type="protein sequence ID" value="KAJ4496981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4496981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="42194" checksum="9B0F16B1596855A7" modified="2025-10-08" version="1">MDSDRKSTVSSFYGGRRGSQDALNNDFPSSSGPSYPNYAQGRGRDDASSFFDPDRTSRNLDGAGRASTAGYNRGSFFLAGREEPVKGGRDEEGGAGGNGGAWDIYADFNNEGPRYSSAFGSSSTPADAYHPLVQKEDVASTIGPVEMVTVPAMGPEWQRDELRNMTKAGRRENKSESRMQAWREWNRGQRGICGKWFTRRMLVIFLFVLCCCIGLILAFTIPRVPAFAFNTSTPLANATGDWKDAIPTVFSRSPTNFSFAAFADLQVNTDSNFLPLTFNHLRATVYDLDTGIEVGSGDLGHRTFPAKTLSSFQLPLNFTYSAVNTRTNWYDACRNAIDDVGGIRPGKSSSVKFTIKLDMDIAGLTTNPSTQAQVSNAACPVELAENAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLC0</accession>
    <name>A0ABQ8VLC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_894766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="615"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="893"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="972" mass="106639" checksum="A5A181B2FFDBEDA8" modified="2025-10-08" version="1">MNELDFRDNRYPSIGAHSSKSTRDQPAPSSMLMASSGWEPEEKETSSSNPPLRNSSSRNGASDIQSSPEPSKSAVSYSLPQNNRRVVERYSLDNEAQQEPTVQQKQHSFQEVSVSLIPAAPRHPSLPAAGSRAGPSNTNSSVSPVIMPLSASPTYSPPISSRQRAYPQQPTYIQNVSHNPVNPVYLPNNPPAEEVCIECAMRDQDMADVDVTSPGIWDRESDIHYEELKRKELEEEASGIIDTEGPPRPKAIGGQLTESNLKLWLSVNPREPTSRQQTLNSYIKSQRTLLEAEALARARAFHEAKELDNRMRDTYSQLRRSAYDMGNSASPADDTGGVRIKPPTSPVSASFPRAHDRSHSRDVTLLENGMIVEHVDVRKEEKEARDRRRKDERRARKSSRSSAVDVNSLMSTHSLVAPHTDSGVGLKPYSRYSQASSARPLSVLTAPLDRPDLPRALSQASFSDVHSLGSPSSRRTRFFGVRSSYWKSQDSLAMSGVSGSMLDMHVALQREGNRGQMVQSPVDVAPGLHRQTWPSTELAPIISRQSEEQPKKKKGFAKIWRIVTRSKKNRSSSARESQSLDRTEDDADYPLAPPPPLSYLVNRGNPGDRMGPRHASTPSLPLASSPKLALSSTTGISPPTAPSTSLPSPASSRQSGADQDTGEGKKTTIVNGDEIEPPNAGYFISSNVHSPISEPDLRRISQTAVPIIDVPMDKHFSQTVSSRLTISTLSREKSLPPLPNDAVIRPYVNARDNSRPRTVYTFDSRPPGTGAPHDFIPPQAPFRTEARRQSFGGLTSRPNLSGFLSRSTNSKAVVNPQQGLAPTYDEFGASRGSLRLPPADTNSRNSVAHTGPTPTKRRSRFGLSSLLGKKNTSPDRSKEAYEPQYQPYTVPNQQGQPQQQQQFPALHTSGSDVHDEVMTGYATSNSRHSGSGGGGPRMSITSRKALDELVSQDAEFVAYRYPSNDQRLDLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLC6</accession>
    <name>A0ABQ8VLC6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_762451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000029">
        <property type="protein sequence ID" value="KAJ4495609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF1">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="261"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
        <location>
            <begin position="533"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4495609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="741" mass="83704" checksum="40FBB406066773EF" modified="2025-10-08" version="1">MLIGVLKKQVSLRTFSYADDRPISYRQEEEYFTSPRRGADGRFTPVEQVRPIDEQFIGGFLPPPSPGPPPLPAKDDIYNDPTFRLPDEIKSQKSISSSQLSRLSAVERSRILRVARMEPHLMFMVGPLLKYDTTDEHGIWHGALLIVTADSSSTYEPHPTLTYQYDPDKLTRHHKRKTFEGKSFDLGPHPADPHSTSLSLSASQINGHASSGPNFTSEQSPAQEIWLEGKPLTFTFWRFMIHIPLGPNEMKVAYSINHGQQLHFFVPGRNQNMRWASYSCNGFSAGVNPDDFRGPGFQSGFDPCWLDLLAHHHEEPFHVLVGGGDQLYCDGLTREPELQEWVAKLKPEEKQNYQLTDEILEAIDRFYFNHYCQVFRSGAFARANCSMQIDGFGSYPDDLQNSPIFRTIGTRGYFFFLLFQCFINVDVDGVDDKNHINRSIIIGAPGPYVGFPSHSFLGYLGPQTSILLLDCRAERKKDQVCSPLEYEKVFARLHQLPSTVEHLVVQIGIPIAYPRMVALEKILESKYNPLVALGRNGSLGLSGFVNKFNAEAELLDDLNDHWTSRTHKQERNWFISQLQEFAKVKHIRVSFLSGDVHCSAVGVFKSLKDKNNPEVPSPLDYRYMLNVVTSAIVNTPPPGGVIKLVASLAGKTHKTMHKSQTDETMLPLFTKDPDGSNRGQKYIMGRRNWCITTYDESTGDLSFDIRVEIEKGIGQTQGYMVRTPPPRWERSLAATLSTSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLJ1</accession>
    <name>A0ABQ8VLJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_894821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="59"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="491" mass="54314" checksum="F5EAEDEFE19031FA" modified="2025-10-08" version="1">MASTTNPLVTGSQSGDDLNGKISPVSVSNSDFERTVCGIPVRNQATFERRVMRRIDLRVLPLLGILYSLALIDRSNLGVARIAGMGEDLELSIGSRYSVVSCVYFIPYILLELPSNMLLRTFGTRNLLSFCVIAWGAVQLAMAFVPNWQYLALCRVLLGAFEAGFFPALVFIITTWYRRHEVQKRLAGFYLISLLAGGFSAILAYSFSHLAGKAGLPGWSWIFVIEGAVTILIGCVAWAFLPGFPDNNTFLNSEETRFILERIEEDRGDSLPDTVTLWKAFEYLSDWKIWIYGLMFLCATIPAYAIGFFITVILSGMGWNLEFALLLSAPPYVFAALSVFVFAWLSDHFRSRAIFLTAQTILTLVGFAITGFVERPGWRYFGLFLGNAGSAGCVPGILAYSSNNIVSHSKRAVTTAIIISFGGLGGIIATTIFRQQDFPRYIPGISVTISCQALLLVLLGVLTLNFRYHNKTKRNTLQPAMGGRIDFLYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLP9</accession>
    <name>A0ABQ8VLP9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_917683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4497333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="36915" checksum="95A15FC77E7EC56C" modified="2025-10-08" version="1">MIKRHPTYWFNDGDTILHQKVLSDHDDNDIFYRIHHSRFSWPESPKFLPGSSSQLVSELGSYISDNDQNTFRTMGENDSDEELLDGLNGCKYVVLDHEQAIDANDLVVLLDHFYGKNVLSPESDLTTRIVPILRITSLDQLNIPTLHEEAKKSFVRSFPNNAQELANFQGECAEEALAVAIQYDIRQPQKPLLYYLATQTHLELHEADSQDSRTSISTLSHTISTHMISLFTPLLFTPPPTSHMECTDALAEHWMPLVIAPAIEDSAMGKPLQTLERMKDVNWSECGLCEECVRIKREEWTEEQDRVWKIMDTWILEADAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VLR6</accession>
    <name>A0ABQ8VLR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_917679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000022">
        <property type="protein sequence ID" value="KAJ4497332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="287" mass="31715" checksum="FAD142FC3CE93760" modified="2025-10-08" version="1">MNHKKLNRLAKRHYRPSSGSDDDDYKPSESQQLSLVAKKHRPAESLPTHINGSPLPPRSSFLAAMDANQDLADSHVFDDDVGSQQFIDNLLATNGLDSSLNSEEMEDYNSDIDNVEYNLESQKPDLYGSSPAPSSPGKPLSTYYQIVTEEYGVTEIADLGQETSAFCPHSASACACADFLLTQYHQLNKCLAQERHENEQLIAQNFRQNIRLKHVAHLLGKSLGSFGRSHDAEPNTLSIMKKEAEAALVAARKDAEEARAAQKTAEGLLQLANNMRLEILALVQDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM05</accession>
    <name>A0ABQ8VM05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_895302</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000030">
        <property type="protein sequence ID" value="KAJ4495461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF7">
        <property type="entry name" value="DRUG_PROTON ANTIPORTER YHK8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4495461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="460" mass="50633" checksum="7CA4161B93968359" modified="2025-10-08" version="1">MSSSSSTRSQTANNIEESLEVRSLQYEVTLEDHEHPQSLARRRKWLIVLVISSSALCVTCASSAASFTEDGVSETFHVSREVTILAISLFVEGLGLGPLLAGPLSEVYGRNIIYRVSFILLFAFSFGVAFAPNIVVYLVFRFITGFCGSTFLSVAGGSVSDLFDNKTVANPMAVYTISPFIGPNTNWRWTYYTLTIWTFTQTLALFIFVPETLRKSTGDESYFAPLEKGEINLGQAILVSCYKPFQLVLYDRMALLLNTWTSLILGILYLAFQAFPIIFETNHGFNMQETGLAFLGIGLGMLCGLASQPYWNRVFAREAEKNGGVAPPEARLYMGEIGGILTPLGLYFLAFTTYSSVHWIVPIIASIFFGTGIYFVFTCVFTYLVTAYRPIAASAMASNSAMRSTFAAVFPLFASYMYDGLGTVGATALLAGVMTLTIPLPFVYRRIGPRLRAKSRFAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM07</accession>
    <name>A0ABQ8VM07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C8R41DRAFT_943797</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="3"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ4497438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="398" mass="42996" checksum="2A67CCFA9FE9DB9E" modified="2025-10-08" version="1">MIHFAALCWCFILEGWNDGSVGPLLPVIQAYYSVGFAVVSLLFVFNCCGFVIGAGINIWLNERLGFGKVMVLGSLLQLATYAIQSPAPPFPAMVLSFFLAGLGMSLQATYSGIQNAQANGFVGSLKKNKSTKLMMLHASYGLGAFCSPLIATQFSQTRHWSFHYIISCGIAVSNTTVLCAVFRLKRQEELLKETGQEPNEERPSNGVALTSNNLYRQIFNINAVHYLALFAFIYVGVEIVTFIIRERDGGASAGYISSGFFGGLTLGRLGLIYINKKVGERRVVFIYVLLSIGLEITIWFVPSIIENAVAVSFIGAMLGPLFPILVGYGARVLPPYLFTGGMGWITGVGTAGSAALPFITGVLASKYGIKSLQPFLVAMMCTLVGIWAVVPKGRRIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VM85</accession>
    <name>A0ABQ8VM85_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_865538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000021">
        <property type="protein sequence ID" value="KAJ4497480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF1">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="199" mass="20969" checksum="E5ECB4A9787AFE30" modified="2025-10-08" version="1">MNNADRQTASSSSSSPTQEKRSLSEQISFIGARINRALSRGRSEERSARDFDNDSLVSSSATVVSVEGRGGIGNIVASVPEDAVVEQSVSPIRGRDISRPSEVPTGLPFAGSTGRGGAGNIRAPSQEQKFDSDAITLVPSYLYRQRSSDTSNVRSPSQTSPSRNMLSTGRGGIGNIKRNPASDLNTSQGAASDEQNGHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMH5</accession>
    <name>A0ABQ8VMH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_821585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000020">
        <property type="protein sequence ID" value="KAJ4497570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051040">
        <property type="entry name" value="COX23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811:SF1">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4497570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10318" checksum="E34D03439001E525" modified="2025-10-08" version="1">MSTKSDAVPLPPASANVKPLNYREQFQGREVVSRFIDPCEAASKATMACMNKHNYDREKCLDYFQAYRECKNAWIEQRKDDRRNGRPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VMN6</accession>
    <name>A0ABQ8VMN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_760184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000023">
        <property type="protein sequence ID" value="KAJ4497171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4497171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="428" mass="45715" checksum="AFFFB1B5B4DA7E51" modified="2025-10-08" version="1">MKQPLRRFSFRPFALQLHLEHNDTLSSFQEREKKEQASVALSKRLAKPISSSSDKRAKQSALLVRGLIVGPTASSPKLSSAVAKPQMGKLKSQLMQAKSANKIIAHLRTLSADSAEPKPTGPIHAVCLARPDGEEHELHFSKLGTTTPPSVSSFAVMNSAPLEALSSLFNEMHVIDLVKSPDFGLGQPGDGNGILAGALPTAETVINGIEQITPQLMALGYATGRAVMPDHTGIHPPIDRMSVLTYWWGLEVVLPPPSLVYLANAQSISGSVVNFLTALAVINNGVREILPFVRYISQFIDFEFKTIQSQDKGKGVVCAATWIMPAAMVPRPWDFPPPEPKLVSKPTVPTEVEALPPVSPKSSKPDESIPAETSPFSPPAMSLPAKPSMPHVTPIAPTLSIPAISTNSTVISTVTQGSPVVQPSISAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VNM8</accession>
    <name>A0ABQ8VNM8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_791375</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_uL3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4497998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="321" mass="34925" checksum="F6301A93421C8DB2" modified="2025-10-08" version="1">MLRLWTLKQKPHRNLILKCLHGSSNVGASPTAASTSSVSSNAPSPPTKWTPDSIRTGLIARKRGMTALWNDQGARLPVTVLQLENCQVTANIVTTRQDKSEYHAVQVAASDKPLKRTTRQMQGHFRKAKVNPKRIVKEFPITSDAHVPIGTTFSAIHFVPGQYVDVIAKSIGKGFQGGMKRWNFKGLRASHGVSVSHRSAGATGAHQDPGRIWPGKKMAARMGGQRITTQNLAVVRVDTSLNLIYLRGAVPGVDDAQVMVRDAKKLAAVGRHNQAKGLYEKVLPKGVDDLPFPAGTLEMAKTLPSIIEAPAYRVSPFVPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VPX0</accession>
    <name>A0ABQ8VPX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_864857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4498397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="140" mass="15837" checksum="C2123C2EDF9690B9" modified="2025-10-08" version="1">MIFGTKLDHTQILIQLDKDIECSLRLEGPNQLSVLGHFVDDVPSVNVTADPRPKALKRKLIETGASDIDSKRVPRIQVPRTQVPRIQVPRTQVPRIQVPRTQVPRIQVPRTQVPRIQVPRTQVPQIQVPQMQASQTTQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRD1</accession>
    <name>A0ABQ8VRD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_893828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4498871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="362" mass="39019" checksum="B3D4BC6CF6D9D8C9" modified="2025-10-08" version="1">MDHKKILMELSKREDLKNKWASLSFGTFICPQCAGLHRGFGVHTRCMDTWQDEQVKRMQLGGNAPFRDFLRSYTPVEQGGYSDTLSPYDTCHSWAATQYREKLRSGKDWSPSPPPEGTAANTSRTPKRPSSAQGLRKSRATSRAMASSAIRSSSDASSPASMRGTGSNAGTPDLSRSGTSALKTKNENSFASLDHLNANRPLDLHPSQGGRYTGFGRTPAPSAGSSNASYGLSSRAAPSLQDLQQNPLGALSKGWSLFSSAVVGASKTINETVIQPSMERDTGPEFQSNVKGILGEAQKHVGEKVGTLVGGVGGNPRNQGYGHVGSGYGEEETSEVYHDNDAEYWGRHDGWVYSAASYHHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRE9</accession>
    <name>A0ABQ8VRE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_755987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000013">
        <property type="protein sequence ID" value="KAJ4498922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021013">
        <property type="entry name" value="ATPase_Vma12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11712">
        <property type="entry name" value="Vma12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4498922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="229" mass="25416" checksum="E38997E3C117FEE9" modified="2025-10-08" version="1">MSSEHSVNVSLETHLVSALEPLLFITDASLSIRLAQHLSDPRGIIPYDILLSVSRWSRSATGSSALRACSPPLDPNSYTMIALLAGTTTSPERKFGPYQPPQEPERLVAQEKRERKAITTIINGVLSIIGSGAAAWIGSERTNWRQEWRVLFALFVAVVVAISETALYIIWQSRSSSHLTTAKTRKHIRAKKEDNENPSLPNHSPTNEDDRGGLRLRIQKKPTSNENLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRU4</accession>
    <name>A0ABQ8VRU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_864271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040096">
        <property type="entry name" value="Ric1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746:SF10">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746">
        <property type="entry name" value="RAB6A-GEF COMPLEX PARTNER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4499103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="514" mass="57570" checksum="192A99D8ED0F718B" modified="2025-10-08" version="1">MYFPTSTARRLSIVPALPNIPPENVLTICPSPRKSLFCTLTRNGISIWRVQPSANLAFLSRTPISIIDHGENKEAFWSPDGSRIVIKTSDSYLVLVTVIFHPNETIYQAPPLSTNAQRNFLAGPGEAFPSSSVSLQFEGVIRVEGTLISVSPRKQSVMFSTQNPPAIQRIPWPASEEVGERGSDEEEYGTRRRKLDNYDQWIINDGDFGWLVEPEVTISQILHDRSTGVESWIASDGRAYINYLVIPRMLQTSTCPKTTNFKRKSLTIPVFPDGQRNVWIGTCIHDFETSRWVQKQRRVEPEEHGSVYFEPRRAVRLAINAKFSLIAVGMLGGGIQYTTFPVDEGAVPTSQQIEIHNPSSRQTGPVYSMEWSSDGYVLAVGWQHGRGLFSVGGRCLVSGFGVEDVDEQNFQDTFMNGVLNLFWAPGNFELIVLAPPSMKFHQSLTFRIAIDGQLFVIPFVKSATTGQHSPDNTRYAFLQLEDCALVYRGADQPDISIINPESDVWQHIKANFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRV7</accession>
    <name>A0ABQ8VRV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">BCS1 N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C8R41DRAFT_908871</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000018">
        <property type="protein sequence ID" value="KAJ4497954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="46"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="259"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ4497954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="462" mass="51977" checksum="0794001D840D0043" modified="2025-10-08" version="1">MSTDNPNTIIKEGLNDAAAPSPLQNGTKNWLEGLDNPYFQAGFGLMGVGVVFGGLRKFTTFADVFLRRRLLVQVEINNKDRAYPWLLSWMAQQNQINQSLGRVSGSLISKSHRLSVETTVEQHQNGSSSVFFNLVAGTGMHWLKYRGVWMQVVRERDTQSMQMMSGNPWETVTLTTLSRDRDIFLRLLAEARDLAMRDQEGKLVIQTPWGTEWRPFGLPRRKRPLHSVVLDNGIAAAIENDVQSFLNRRQWYVDRGIPYRRGFLLHGPPGSGKSSYIQALAGSLNYNLCLLNLSERGLGDDKLTHLLSTVPEQSIVLIEDVDAAFNKRVQTSEDGYQSSVTFSGFLNALDGVASGEERIVFLTTNHIERLDPALIRPGRVDFTQYVGDATPNQARSLFERFYGTELLETIDVGRNLYDLIEEEMKQGKRISMAALQGLFIRNHDAQSALAACRQTFLEIKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VRY9</accession>
    <name>A0ABQ8VRY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rof/RNase P-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C8R41DRAFT_818965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ4498387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="239" mass="26464" checksum="B8CD1ADA2CDD41CC" modified="2025-10-08" version="1" fragment="single">MDIYAQSVVPSLQKARLVFNSKDPFVPSFVQNSLLPSVNPQEIYASRIHGRRILLDNPIGKGDKKPKKKKKKSTTNCNIPRISGSWSLDAHQAKFDLFVPLHQLWMGYMSELLALNSAEPPSSASAHPKLLKADFSGSFISVQASKNPSLSSIQGIVLHESENTFVIITRDNKTKVLPKQNTIFTLCVPATSVSQSLPSAATIVLDIPHLAFTLYGNQFRFRASDRAGRKFKSKETVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS03</accession>
    <name>A0ABQ8VS03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ornithine N(5)-monooxygenase [NAD(P)H]</fullName>
            <ecNumber evidence="4">1.14.13.196</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_893754</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="4"/>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802:SF1">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="442"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4499132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="550" mass="60624" checksum="04CBF24EC75FA37F" modified="2025-10-08" version="1">MSTGTESTYPAVYDLIGIGFGPSNIAISGALVEKWTALSNDAETSFQKVLFIERHPSFQWHPGMLLPGAQMQISFMKDLATLRSPQSPLTFVNYLHSQGRLSAFINRGSLTPSRKEFADYLEWAARYVEAQGVNVNYGQEVVAIDESMDGLITVTSITLADGKLNSFITRNLVVSPGGRARIPNVVVPFIKEPSIVARSTLLHSSEYKHRIGELLESITSERQRPLRIAVIGGGQSAAEVTMNLHGLLNDLPAGDGPIGHQVDMLLRKGSLKPSDDTPFSNEIFDPEVTNDWFSTSEQGRERIMAEYKATNYSVVNPRTIDALYEMIYDQEVDEAIGARNSTVFTPRPRITIRSHMHIPSLKYDTGSKNFVFTLQNVRTREVFENESYDAVVCATGYQRNSWTKMFRASDRLGKRFGIDDSASDIPIKLVPFAQRVADTADLDQPQDSPLSSVSSTPTSVVTTPPISPGAENVVKQESSPTEAVKLYITRNYRLLPMASTKTMQDGSAEGLKARIYIQGLEESTHGLSDTLLSVVSCRAGEVVDDLLNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VS29</accession>
    <name>A0ABQ8VS29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_711302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="208" mass="22488" checksum="5CF45AAE7B24E1BF" modified="2025-10-08" version="1" fragment="single">LSSGAAVEADIDASKFEAAHGAHTGKPGKKADMGTKSDREKRYTVAELIDMGFEHIQWDGVTPIPIVDCCGRIIAVLAGQPGGDYPEELQEAFGIMQKEGENAGLSSKATDGPHKRGAFPAYNRGVTMGMGNAHPVVLNPRSMTQVLNRLVGHSAFRRMAKYQNAAFGLWAPRVYEEYEKVHNTMHANLELPENFPGVVFAAAAFNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSF9</accession>
    <name>A0ABQ8VSF9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_915517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000011">
        <property type="protein sequence ID" value="KAJ4499310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045477571" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="17"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="80"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4499310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="541" mass="58435" checksum="3896FC9426BE2EFF" modified="2025-10-08" version="1">MVALSDLFWLVTSTHNWCCSSSVEQTQNSSVASSSAATIAVQSCQQLQQSLGPTVVQTSTSGSDYILGANGAWSTFNTEVNYQPTCIVFANEAEHVQTAMQTIYQNEADYAVQAGGHSGMTGWNTIQDGVLISFKNMNTSSYDPDHDTITMMPGVRWGEVITEMEPFGVAPVGGRISEVGTGLLLGGGLSFLSSAEGYASDNYVSLDVVLVDGTLVTATADNEYQDLFKALKGGANRFGIVTKYEVKAVHTGTKEEKRWWGGLFVYPNSSSEALLGAIAHYTHDTEDTNAVMVTVIMTTWPSLEPSISVLLVYNGTEASFNHAFAEFLSIPYTSSSPGSLSFLELSNAVHFPSGMGTLFSASSLAGTPANSDVSVDDYLELYRQYNNFSTTFASSSDIGFTLLDFSPVLQSQIRAGYKKGGNPINPPLGTTGYSIILFQVTYREGVTQTAEDVEDGRQFWIENAPSTPGLPLFLSEADAAQQVFATYGEYDFLKQVYAKYDPTSFNVRHTEGPLGLESVLTPSICEPLSIFNYSLPLPLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VSG7</accession>
    <name>A0ABQ8VSG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SCO1/SenC-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C8R41DRAFT_819014</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000016">
        <property type="protein sequence ID" value="KAJ4498420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017276">
        <property type="entry name" value="Synth_of_cyt-c-oxidase_Sco1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151:SF5">
        <property type="entry name" value="AT19154P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037736">
        <property type="entry name" value="SCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ4498420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="280" mass="31705" checksum="5C8D9EED6F521655" modified="2025-10-08" version="1">MLSLNHFLRPITTRPFSTGRCLVRPQKHLSGAQLWKRHAGTSPEPSQPSRPSSEPSRPQRNVIGAFTPTSAAIFVVVGVGLFWYFRNEKAKLQEQREKERMSKSYGRPHVGGPFSLVNCTAAPSSSEQRFTHEDLLRRWSLVYFGFTNCPDICPAELDKVTAVVNELRQSNPDLPVQPVFISVDPARDTPSTIRTYLTDFHPSFVGLVGSFEQTKSVCKAYRVYFSTPPDADPKGDYLVDHSIFVYLMDPEGRFVEAFGQTAEKEEMVDKIKQFVVEWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VT26</accession>
    <name>A0ABQ8VT26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_755313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000012">
        <property type="protein sequence ID" value="KAJ4499106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="332" mass="38848" checksum="C5540A5CE2315F7C" modified="2025-10-08" version="1" fragment="single">LQGSIMDAVRISDNKPVMLKAVSRIIHPQEVKIGMYFSSKSMASDLRNHCIPIYDVFPVPDSEMDLIVMPVLRPFENPQFDTGIQFMHEHLVAHGDCTEMNIMMDGSRMYPEGWNTLRPWQARDDPFRAAKRAGFRMQFWPKYYLIDFGLSHMYSSKRTVPPLERILRGGDKSAPEHAPKYKSANPFSTDIYYIGNLIRENFTERRNSTLCARFSFLKPLVDSMVQDDPIKRPTIDDVVMQFDAVLRKNRRHLNFRAAACDLQHFQFADQIPALFRRFTKYFVIRRSLPVLPHPRRRLSPELHWMYSGPPTEYPEGQERPTFLYVHDLDDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VU55</accession>
    <name>A0ABQ8VU55_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleolar protein 12-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_916738</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000017">
        <property type="protein sequence ID" value="KAJ4498100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019186">
        <property type="entry name" value="Nucleolar_protein_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09805">
        <property type="entry name" value="Nop25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4498100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="244" mass="27300" checksum="173FD770BA2B6EE4" modified="2025-10-08" version="1">MSPPNLNVLTQAHTAIAAKKRAKRNQVQEVIFDDTARHDFLTGFHKRKLAKTEAAKKKALEREKQQRQEDRREVRAYLKSLAVSLTLVQQRRMLRERAAENAAEIEKAYGATLAPSAGDQEWQGISDPGDQKEQEYEDEEVLATVAIVEDFDPDTLLHGPTKTVSDPESSSVPVVAGPSHRNSSDPAAKLTRKNRPKKVRYQTKDARKSERTKQRARRAEKAELAGGKASRKNRNAGGKGGKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUC7</accession>
    <name>A0ABQ8VUC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_570326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000008">
        <property type="protein sequence ID" value="KAJ4499978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4499978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="541" mass="59456" checksum="2B6405E67E10163D" modified="2025-10-08" version="1">MFPITSYFQRKTKKENVNPPKKRKQILSDDDEISLQPSGSSKKVKVDAPRRQQLSNRTKSLNKEGFSAAASSSTSASHTETISRRTPPHHHYATPQSLARASNTGYTSDSIIDLTTGPSSSTQPQRDTNANPFLIQTPRPLPSMIVQPAPASSIHPPKASSPRHFKAAGAFYSEMTSSSLPSIRQALSRSLVTTTPNTPKRSNHTTEIVPATPESPLLRLPIVPDESSHLSVPSSQNQEAEMDFLVNRKHKALTPDATNKLDDLSQVPTSQSQEVEIDLHVHRKDVSLAANATTGDELFDLSQVPTSQSQEVEVDLSIYRKYNAKEHHSAHPPSDEIVPCSQSQDFDGIFLEAVSPRRKRVLRELEQARQVATATDLSSGSGSRTSPTKCDESQSIFHSPVEVQSMTDEAVKSPMLSHENIIPYAAQEAISESPNIERPESNHAMVPINDEDIQSLFEIGLPSMPPSQAASVTESDSGDEQWMLRGLNTDARRPVLTSEVSRDSVRPLTQSEVQSWQTDVSAYSYPRDVLDFLDMLEGGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VUT1</accession>
    <name>A0ABQ8VUT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_863734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000009">
        <property type="protein sequence ID" value="KAJ4499751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="397"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4499751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="674" mass="74199" checksum="630D14268CF9A25B" modified="2025-10-08" version="1">MSSRRASRQSGGNKPVDTVVASTPTNENPRETRSRKRKSTGSKPDNRELETEQPAKRLRGSRKEDTIPASVSTPQFSRRQRNKNKNVLAPTPLDSAIQPMQATQEMPTPTRKPQRNTRTKLSATPRGILALTGADTPKSRGHVAAKTPVITQTLNQIRSDLLFNQRHTRQEIKEAQEGNDSDQDSDLNGDIGDIDCEVERQNDSEAAKHFNEEVPIHAAQFPSRSHGRKNRTGDTGMVNNRSRQVEVEEDIEEALSSSEDNVPKLAPVTKKVQRMAAKLAVELPVVSTKDADMPAPTSTLPQFQSAEPAWLPHTNLILKPSTDATWSYRLDLKAQNSQVRSVVKAARSRATLELVTNGKECGLQTSGLNAITLGALIQCADELGFDADLDLSHRLEEGDHTTYARPLIKYVAQRVILERRTLKTGFSSVVLTAFGLDYSEAGIEEAKQLVANSDYIYQLLPSGLYDYARPFSHNVIYKYLSAALFSSTKYSKLIMSRKASIFVSSLPHKPLELELPKAMVAMASCVIHSILQDHAKFTEENFPPTGLHSQWSTFMAILTNLEIASRVNYHKLMHKLYLQSSRTVAPTEHGLSQDQILQRINLTAFAANGGDDDSSRSSSESDPVHGGSHDGECTISLSGDGMADSLTANGNGSVIGREDEFNKDRAGKETEVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VVZ2</accession>
    <name>A0ABQ8VVZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_426046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="41"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="650" mass="75552" checksum="2BADBDB55852744A" modified="2025-10-08" version="1">MYQDDRYNERYYSISSWLDSREAIESNQSRHDMNLRRHSTGTCAWLTDNTDYRDWEQGASSPSIIWCHAPPGTGKSVLCSQVIRRLMDIPSVTCAYLFYQFDAPYTAVETLRLLAAQLITNSYLTYRHKISDKLYLMSQGARTFDSLSACIDMLLPQFQTVYLLLDGLDEECVKDRWSEACRVIDFLVGMSKAHPRIVRLWFSSQDRSSIRAKMEKFTICNFHEPMKEDVSIFLASLSSELEDLIASEQAKSFLLEKLQRRGESNFLWVNLMINTLREEASSPEEVTRLLEDGLPSTLDEYYRRIFGRIEVNQRSLVCKVFSLIAFARRPLRMSELREAIGILSIDISTSLNSRHIPFEPHLRKLFAPLIQIYPVAESEDYTCRLFHSTVRDFLRKYGGNVFPEFSSGLVVSPEISARACLAYLRQQRYSLTLRHEDELWLDSNGNAVKEHSFLLYAAKYWDKHFDEVLGDEVTRNAIVSFITSSNFQTFVQIQSLWLENRFTIFRQSNGCECDDCTRIRFLVRVFPLWLINGIEATNERRLWASYRRFIHDWRHFLSCANCEKRGCLFARCAGEIDRCWWGALGPRNFLSRLQGRYRSFSFQREGIVTTEPGPSFEGITQEGDKMKILRLNASDASSGTLTFTCEHWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VX97</accession>
    <name>A0ABQ8VX97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_914226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000005">
        <property type="protein sequence ID" value="KAJ4500636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21383">
        <property type="entry name" value="GAT_GGA_Tom1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045007">
        <property type="entry name" value="LSB5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789:SF2">
        <property type="entry name" value="VHS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4500636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="785" mass="86966" checksum="5DF84BFB2DDF885E" modified="2025-10-08" version="1">MPLRKSKSFSSKHNATVTTSAPPFDLPPPPISPIPKPNRSHSKPPSFRSALRSILGLNRPKIIANLDSADLDAEFIHNSTTVSTASHVVSWRKHTMTYSSSMHDSPRPYRCMEPPDVLPIINIGFDDSINYTDVAHEHEHSTISTTTTSSRSTTTTTDPTSIDAESNVPSFELSNTEKDAGFRGLWKKVKPADKPDEGFPFENDDAMFNPPAVSGNGRGSYYENIPPSAAVQYESTNDNPITEPKKERSDRDREGRHKDREHREHREHRERDKDRDREHRHKDREHKEKKSSKNRIIPLEEDIRRLFQECKIGLGNASLLSQACVHAKVEELKKGEVIKEFRLKCLSSQELIAAQIPWATAGAERSRKEKEREKALLYGENNDPSRRSRDRNRDRSISQLADAAGIPATDFPVDEQTTEEQLLAALLEANGELLAALGQYDDVERVAMERKAEEKSRKEVRMDRRAIATLEQQQQLEEIAAISGAGAGGSTVHLTSSRSPSPASYRGSRPSSMVMQHPLPQHPHSLLTHPAQQQLQHHLPAQNSFSSHSPEVPGTTLAPPRAPPHGPRSPASGHGHGHTRTGSSGFPPSRTPSPNTPSMDHSSSGTGTGESVGGSALDVVRDIDLVDGFDSLHVDKGRATWSGRIPVDDSSEEEILTPIKPSAKALGKRRVEVNDATENSFNPDDIYYDQPRDLGLSDPYNPYASDGDIPVPSSEGGYNSDSDDSESAYYPNGRPRSRNNGLLHNLHHPPVHFVYDAAAERTQQRIKKMELENHMEKSMEVGGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY40</accession>
    <name>A0ABQ8VY40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_913224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="129"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="221" mass="24711" checksum="B83E27A55DB8CE40" modified="2025-10-08" version="1">MGTRRRSPLCKAGTRRAPRTSHSRSHPMALRRPVSAQMSPASVAPTSFDTPLMSSPNAGDSGSPSRNRLESVFETQTLKYMEESNDILQTRSQTLLLLNQKLASLNNEKERLNTEMEQEIATRASEYQCPLCLGLAWNPHVLVCGHSFCSKCLGQHKAEHDRKRTANAIGTDLDPVIRCPTCRSLILRKPQFSHTIQSGVESVAKYLHEDAPSAHRLEWSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY41</accession>
    <name>A0ABQ8VY41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_806690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="52" mass="5817" checksum="D66E98FBFC367604" modified="2025-10-08" version="1">MRDGLFGGYFLNLRQYKAVILIVGCNGATSVSSTMLLRIPIFMHSGSYLRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VY85</accession>
    <name>A0ABQ8VY85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CxC1-like cysteine cluster associated with KDZ transposases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_749665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="763"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="822" mass="94425" checksum="3AE0417CE9041C7B" modified="2025-10-08" version="1">MDELTEAYVKWKYNFNLSDNFNEEYSFKIDAVNIYTLEKEVCIHRSENTKAAVALVSAGYLGTSPEFPSLAISLQTLELYYTLRLFKPSFSVEAFAKALCHLYSIPFHRGYRTGLSDTFDVYLAIRRRIDSQVAKELGHEGANYCVLNSCPACCYKLEDEPELEFSRMWVVDRNNSLKRMAGIGNREVSDTRIFGESDYYLSEDFVNIYAGEIKARPLACNIEDEDPDELQSDWVDEEHGDPTDGIEDSELAQCTENWKAAAADQQKKMWGIFHESGYFASACRHGFVLWVADMIRSGELAKYPLAIVAKALGVLPPRWLMGYDIGCSFGGTILRSSLGPEFAKQKCRTCVNAFHGYSHNAACQQKYHPLNILGMGLEDLETLERLFSSSNQLAPLIRYMTAYRRRVFIDIFLQQWDQEKYQNLATMLHNNYVQALNILEDEAKALQADLLAKGITIEDLETYFVEESNHLKEIGKEAEGDLHAVAYVELLQRYRELSSACDNAAADFRSQTPADYEFLASAASYSRNLSDGRRAETKRRYLREQRDKTLFEVVQMETAMSISPRWEPTDREYIETIEYMNTRKYRQALERLYKLVIQRLFELHKMNLSFTGYKMRTHISNALQRRSKAIRNAVKTYNSAAAAIGRPTLDWVKVTHYSFLDQFNVLQDTRHSILDKKWADPVVRHLMKQHRQVARAKEEIQHCNIQIRRLQTSIFDEDKKFQKVLEHLKDTSMYFPVHDFINRRRAVNQLLLSRIYQTQALPGFTGNRNPGVREGSGPPTSTSVPMNFDLPDPDSDDGEDAEDDEIVDGMGAVIEYMSNLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYA6</accession>
    <name>A0ABQ8VYA6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8R41DRAFT_913318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000002">
        <property type="protein sequence ID" value="KAJ4501320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="722"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1827"/>
            <end position="1902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4501320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="2158" mass="240282" checksum="CA16716A75B6A976" modified="2025-10-08" version="1">MAHSSSLTDSEIEILAAIALAYSTTSFNYWELENIDLVLRVVDLTGEKLLSLTFSLSYTVEQLYKLLHSSWNHPSTEELTPAGIIFLGTSDFPLNLDLPNFPDVKFAVSLDNISGKIELHPTSESRFILPRFHSLLSLLHDATPLETVLYELTSVTEHEEKLLLQWGVATPEQQSSEHEYSAVIHHYIEKVARETPDAVALQFENHTFVRYGELDQQADNLARYLVHELGVHPGDLVLEFFDRSVEMIIAQLAILKAGAAYVPLDIVHPVQRSRTIQEITNAKVCLTTETLRESVCDRLPTVNAVGVDTFLSSIPSKVSWPPISHSSDGEDLCYVMFTSGTTGTPKGVMVQHSAVVASVINGPAYNQKLRQLGPNLRTLVLSNYAFDYSTWDVFLTLTSGGCLCIAPKDTMLVDVTGTVNSMNVTFLETTPTLLSLLELDECPSLRFVYSSGEALSPTIHRKFLARKLAQKGKGESELLFANGGAPTETTVMSVFGPINIGDDSEQPVYGRPFGGNRLYILDSHGRLCPPGTVGQLWIGGPQVTKGYLGRDDLTAKVYRPDPYAGSGRMYNSGDLCSWLSDGHLRHHGRSDTQVKIRGQRVEVNEVETTILKVLPVKAVCVIKHAYQSREELLAFVVSNVRPSALYVFQALMIFKQGIVLKNPQQMLSSHLPTYMVPSRFISISELPVTSNGKTDQKRLLRLADDLASQRQISEASSESSRRPMSSAQRILLKAWSTSLSLAPEDIHSSSDFFTIGGDSIAAIRVAASCRAEGYLLNVVDFQAHSRFSAQTELLENRPFVGNRPALQQYTPFKLLETGIRDVILSEITEHGYQDSDIEDAYPSISSVAGLVSLAVADPMSYMAQYSFKNFHKFDPIRMNTAWKLVVGRHQSLRTTFVIASELESSIIQVVLKAGQFNLPWNYKAFESDPDMDKAAQDYILQSEGFRLGKVPTTVALFEGANSSTLVIQLHHTQFDGWCLPIILEHLQEAYAATTVSEDWIKASPPFSNFIQWVSSQPPADAIDYWRKKLESVAVPKWPNNAPNILLKTPMKGTTNHSFISTFNDTEQLSTFCAEHEITLSSLISAALAMVLGLYEDSDDVLFGVVTSGRTGDVPGIEDIVGYCVSTVPCRVHIPTDVSLEAIVKAVHDDLLGSTPYQFLGLNDIITTAFPIPHDILRVLLTIENLPGLFEENSEFLGQNLRGFAIDVSYPFAVTVFPSPDNRQLKFHFQWDSEFLSRADVDWFQSHMYAILHAIIDHPSSQLRKSDFLANGETENILSLSRSVPDPLASVRPFFHQLVDEMGHQYPDKIAIERDNHQGRLTFKEYVARANQVAHALQGKGVRPEYMVPVLFNQNTTNTDITIAFLAILKAGGAFVPLNSAWPEDRLQYCIHQTRGQILICETGLEGIATKLASLSELPLHVSRIEDLVRGQPSYTPATPTLQMDSLSCAMFTSGINGKPKGVLIEHADEDIISAATLFPLDCAERMLHLSPWTFNQGLVDWFLSLAHGKTLILADAQSVVTDISEVVNRTKADYVTLTPTLAQKLQHDIPYPHLKTLVSEGDKLPRQVIERWRDRLDLIDAYGSTETTAHCVSANHSRGSRLRPGVIGRPLGASRVYILDENMSPVPMGAVGELFIGGTQVARGYFNLPNKTVEVFLRDPFSHANRIFRTGDRARWHSDGTIEYLRRMEDNYVNIRGLRVDIEEIETTLMFSASSNKITAVVQLVEVDSTSHLAVFFSEKLGHPNAHIRICEDLASYQRLVRELLQTCQRTLPTYAVPSFWLALDTIPLGHNNKVDQKRLRAFFQLQSPKKVRKYTKTLLGALSDRGPETPVEQLLHDMWLPILIRSEPISVHDDFFTLGGDSIHCIRFLAALKRRGCEVTVNEFYKARTIAQLADIVYGRLPANANLSIQNVESPLTNGLVVHIRSASSKQDKTNSPIWFVHDGKGLIGPQYGELGSLDREVYGISNPATTKAELEAAYPSWESFVQSYEPLLPLRSVFIGGWSSGGNIALLLAAEHVRKSRPVKGVILLDSYTGDGFIPTKEHKTDYPDDPAKARAYTQMNHIEKLLVAYPEPESSELEGIPVLLIRAGSDPMGKVARDHPNQAKEKLEKNLWSKVKMEIKEVKEANHKSLMAEEEFRQRVAKIVRSWCRELERTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYN3</accession>
    <name>A0ABQ8VYN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_347416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000004">
        <property type="protein sequence ID" value="KAJ4500682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
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        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="165"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4500682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="354" mass="38896" checksum="B710B0FB630E9D59" modified="2025-10-08" version="1">MSSPIDETFGAAYIGIVVAALLLGISVIQGFYYFTHQNDGWILRGLVAGVLVFDFVHQVLITHTGYAYLITFWQQPAKLRIVIWSLLAEVLFNGLTGFCVQCFLTYRIWKLSGTKVWLTVVVISLVFAEFACVIAFAVIAFLRVKTFEQLSAELKGLSVTVNALAVVGDLFIAGILTLLLQRSKTGFRKSDTMINKLTIFAVNTGALTSLCAVASLISIIAAPNTFIYISFFFSMGRLYTNSLLATLNARKMIRDAAEGINTTTGDNISLPCKGRASSSKVVFQRSRNLNTNISIQVDTTREFLSDLEHGVVRDTHLSDFKHDEVEIEEDLSEVNLSNGDIESNISSGIECTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VYU2</accession>
    <name>A0ABQ8VYU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_804844</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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            <begin position="3"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ4501496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="320" mass="35708" checksum="B9952DAB43AD65E7" modified="2025-10-08" version="1">MKSQRIAIAGGQGKIGKHIVEGLLGIKQLYSLEIIVLSRSESPDVSYAGSSAPVIAVDYNDQASLQEVLNRYKIDTIISTTSGFSPDPFISSQINLLQAALTVPTFRRFAPSEFTAAPSEQVADKVKLFQMKLPIIHSLRKAKQERPDSFEFSIINCGMFMNYLGYGNTKPDGHKAFGHLGAFPYIYDLSKHTADIPGDGEKQIMYTHADDVGKFVAAATQLDVWEEHFEMAGEVTTMNEILRMCEDVCGSKFDVKYNSREDVVARMSSAPEKAIENFFMENYLAIIDGDADLKRPLNLNELVDVKPMGVQEYLLRWWGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZC9</accession>
    <name>A0ABQ8VZC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_913022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
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        </source>
    </evidence>
    <sequence length="1717" mass="183969" checksum="D63E304C8134BB7F" modified="2025-10-08" version="1">MASGPPTNARVNPARTRPDIGFGQRIRNGTADSNSARPSPAPARKTSFTQATASRISPNPASSPIQRPVQSLTPASPSRSTYNSQNDPKITTRLLSSSKQTPSTRSPTTSSPSRIARPRAISTTLPSTPTVLPSRLRTMSSINPGMKLQRSSPTPAGTKFPNTSSTYSAAPRTSISLTPSPRPQSRPTTRPNVKSRITPAHTKPVDDCTGRHNLVSGRGSGLEAEQKRKTQPAQPSQNAKSENADSNDSGDPEDLGLSPTEVTVLKSVWEDFPVNTDASFDPGGSSTVDRTAVKSGYGSIFGFNMVPKSRNSFAVTEGSSEDRSQSASSIGSTLSHFSLVSTKTVAAGPPSPVNPPTLQTTPQYPSSTTTQSSSPSVEVTHPASIAALEFPSEHSMLQSSFAPLSQSSSLSPDSLDVYAAVQYLRTRVSTSALRSGAPSGNADATASTSRVSGSTSRVSLHATAHPTPKLTASAHVNPSTRVSPGSSRASSTAKGSSPLQAKDSNVSVPKTRMAPVATTPEYPPTPLHTDGTVVHRATSRTEGSTNHIHPTELSSMMDVMTSPSSYDMPSSHSFPEASYGQRYTSNTSLMSSDISPSSPFSLPVDSPVHSYSPPASSPPTVNLKRLLSKPAPTGNSSASESESGVITTKSRPVRRIERIDEKNEKQRIEAFSRGRAIESDAECTPPFGNSRERDRARKMEWEAERRLLKERALSHSRPTTSQSTDSSQSKERKGFGGLVRSASWSRTRGPEGTDKAEKKTRNTLKRHPSATSVASPSDASQMKEFPYSSFAPAYTGSILPATRPAPSSGSLLPPAAGLSSSRGSSPTPQDKRRSLIPHSALLKQGLAGISSDDGVTSSGTTPAKEIMIAYKQQQEREKKRERERNERAREKQREKELWQQEDDRQQRALKDQPSPSHYDQSNSLTTSRSQSIFVRDVPSAGMQIHPRERSSSVPNSGAASMIHDSSHLAQSSDQSPSRPEKLLNEARSFDEEPSQPYYTVLGSSKRVVAAEGVKIEDTFFPDFSLSTSNLVEGISSSMGVSLGLGQPSSSPQSEIPRPSTQTWERSASVTVGKPSKTSGAFGIGIGKTLSRKMSGRLGAPKRGPSLDISPLSNTPTLPVHEHGMPSLHERRVMPKNENRTSGSRGDKRSLRLSIDDYATTKGAISPPKKSPAIHRPVLTQDGEFRTSLLKSSLTSSPQPSPTSSSSHSGGKNKIWNLMKRISTGGLRDNYRDNGASLPTSPLPPPPPVPALPKDLSVYSKEMTQKGGEDVTEGLHKRNVTSTTIHSPYGKLSSAGSIKAPMIPSTSTRSGTATRSSSPISSSDIGSSKFFNRSQSQRSSSSSYGEQIPPVPTAPGKTFQLQQHILPPSELYQLHLNLERNKDDPNARPLNSSNSTNYSHSLSSLNTSISHSRSQVNLKLQTQTQQKPALAEEWTIIPTPKEEKAGFSLPVPRRRTGSDNIDEVGSRRPPTAYESSRSPSPTIAQFSTENTINSLTSVSSPSRQTKPSGSALTSTSTDASSAYRESASAGSRFSSLPVIPSKSPRRAASASSASLTSSGRTWSPAIPPLPTPHVTTSVSGHQRPQEEYVKPDADSPSRRGMRKSFGFSSPSESSSHNYIRKRTISSSSRPTTSPADYHPLTTAQIRTTSRLPRSENSQRPNARTSGPLSAKEKDDKWDDLLERSKRAGGTLHLNGGLDGLDSDRLRFSVNDSEDEHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZN7</accession>
    <name>A0ABQ8VZN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_18844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018824">
        <property type="entry name" value="Conidiation-specific_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052670">
        <property type="entry name" value="UPF0654_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576:SF1">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10346">
        <property type="entry name" value="Con-6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11169" checksum="02EB672DFD35E00D" modified="2025-10-08" version="1">MSGNDSQKNPERVAAGLRGTLHNDNASDEAKDRATERLREMGDDFENKTNRGSAGTGDAHQNQVLGGYKATLHNDKVGEAAKAHAREVLDNANASEEPLPQSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZS1</accession>
    <name>A0ABQ8VZS1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_19913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="185"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4501873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="1229" mass="136986" checksum="A149C5F7C6C63627" modified="2025-10-08" version="1">MFYENHNVVEAATRDTHLDTTAAPQDAPVQSVQELEYDGEGDDEEDDEEDDEEDDSASEGDDLREELEEVFEGDFDFRGSYAYSSLFTDAPNPVLNITGVGPIGLPLSPRDAQLIITSATQAPFGHGTETKIDTSVRHTWEIEPARVSFGNAVWRTWMEETVVRGVATALGVPSSTTPPKCELYKLLLYEQDSHFLPHQDTVKAQNMFATIIVVLPSPYTGGQVHVSHSSSQQVFSFDSNSLLSTAVMAWYTDVQHEVKPITSGYRLALSYNLVHVTPGVPPPILPDMHSSIMSLRRVLKKWRTYKYPDIEPNIMCHILSHKYSPAGLSTGFKALKGKDSYLVAQLMPLATEQEFFVGLANLTYHQTGTADGDGGYGDYYKRRRGYGRYGYGRYGYGRYGYGRYGYYDSDCDDDDDEEVPGIDEVTDTTLTVENLFDMAGNKPARSKKISLDLENLVQQDAFEDVEPDEDHYEGYMGNYSGEVEQWYRRTVLIIMPEESARSVLYTSDYALEILHRAALERPGKPSPEDLLFANIVLNNFQHSPATLVTMAQYAVSWNNLELWRRVLSAGNWTASSVLPMKELVAGWKAFSFDSVCNSLEQIVQKAPQISRGISLIRDLVENGPQEDCQMAQQWADQLISQLLTTLEAPTVQDVSLLIETARKQGLSYLTCTLIPRLEKKSGLHDFWLAMIRELESNRTYFVSPPEAEGSSTSETQNQFENTKKRCLDIVLCNWEHGSADPPPVNNTPYYSHRPRPPPQSLVTHTTRVIQILDLCIDVGVLGICKVFLGLVMKKKPPTSDNFQTLYSPVISHIRQKLSTTNESVSFNSDVFVDFMGLILQTLKTPSSADVPWIIDILQTKGAPYMIQSFVPRLEKNVALYHFWYQFITTLVKDETAIVTKSTATDPDSKNSVPRFLDPLTRLWSLLAKAKPLTLQENFQTIYNPLIPQLRQLLTTKNLDISSSPFLELIQVVLGSYLRFVLGARPNPNALVPARKLGCGCSDCQVLDNFLMSKSLEQTFRLVQARRTHLERQLYSGRDLVSFTTIRSGSPHGLVVKKNRQVADYQSWMQRQSQTKTFLGTIGDGNMLRKIAGHRYGDVLTAFEGKQQFMLPWNSVASTSASTNHSSSGATGRTPSTTNSNPTAAPINTSLHGAPPPHLHNPGPSSTQSTSYMWPSQPALSASTPAIVMALGSSNPMPMMTGSALTVPGTNKRKKSTMVSMDTIDLTGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8VZW8</accession>
    <name>A0ABQ8VZW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_284047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4501075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="417" mass="46329" checksum="D04D36715AD6FD38" modified="2025-10-08" version="1">MSQHDHLLKQLCGSSVETLERARELLYTSTVKTAPGSGFQLKDPLGRPAACALIASEQLKNTVVDPASAQGNSCLNPTAFKKCLAEVRAALAHDASNQPITPTQRRQTRSVSTPRASYDSLVAKYALSQTYGDRFVGWCQRAEFAFFDLGKGNNIARDSPKLKYGIFFWVCGILEPGQLDLLSFVKDSGAYSDNTRRISKVMDVYGTKIRTLIMEESKRSNDAVIRRSSTRVSPGKRMMREAPSKDSPKKQKLSTEDDTKLTTPHKQPNTLFQALDAPKGMFPPSRSPRKSPFKPSFQKLPTRDHAQDKAITQDSDVEMTLPQTPSKTSHRATSSGGIAYIPATSPFPIRRSDRLNSTTASPSKSGTLDLENSLDDVDKLPTVRKRFRPVFLDRKQWGAQDPTLIRLNRRIEKVALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8W0U5</accession>
    <name>A0ABQ8W0U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Thioredoxin-like [2Fe-2S] ferredoxin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_748980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000001">
        <property type="protein sequence ID" value="KAJ4501612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371:SF3">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="245" mass="27268" checksum="40E0E7829DF348BC" modified="2025-10-08" version="1">MFARLPRQVSQRALATRRSISSTYSRRSDALFVHRDTPYNNPKIPFEFNAPNLKRAEEIIKRYPPQYKKAAVIPLLDLGQRQNKGWTSISVMNYVARLLEMPPMRVYEVATFYTMFNREPIGENFVQVCTTTPCALRGSGEILKTVCNELGGIKPGETTKDGKFTVIEVECQGACSNAPMLVIGDDFYEDLTPESTKSILGAFAKGQKPKPGPQSGRQTSENAAGLTTLTTKPYGPGEFCLPEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZP56</accession>
    <name>A0A9W8ZP56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide chain release factor eRF/aRF subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C8J55DRAFT_464173</name>
        <name evidence="7" type="ORF">C8R41DRAFT_765969</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000074">
        <property type="protein sequence ID" value="KAJ4463349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000040">
        <property type="protein sequence ID" value="KAJ4491795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZP56"/>
    <dbReference type="OrthoDB" id="10254527at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018444">
        <property type="term" value="C:translation release factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000001">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.960.10:FF:000001">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000006">
        <property type="entry name" value="Peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="entry name" value="eRF1 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03676">
        <property type="entry name" value="aRF1_eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="5">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ4463349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4491795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="438" mass="49262" checksum="D61D0CA944D10E80" modified="2023-11-08" version="1">MSQDAAEQNIQMWKVKKLIKSLDSARGAGTSMISLIIPPKDQISRASAMLTQEYGTASNIKSRVNRLSVLAAITSTQQRLKLYNRVPPNGLVLFVGTILTDEGKEKKVSFDFEPHKPINTSLYLCDNKFHTEALSELLESDSRFGFIVMDGNGTLFGILAGNTREVIHKFTVDLPKKHGRGGQSALRFSRLRDEKRHNYVRKVAELAVQHFITNDKVNVTGLVLAGSADFKTELSQSDMFDPRLGAKVIKVVDVSYGGENGFNQAIELAAESLANVKFVQEKRLIQKYFDEISQDTGKYCFGIEDTLKALELGAVETLVVWENLDITRYTLRNAAGEEIVVYANKEQEKDREKFFDRSTGMEMEQADEPQSLLEWFAEKYKDFGANLEFVTNRSQEGAQFVKGFGGIGGLLRYKVDFSNLTSIDEEEEDEFYSDDEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-11-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9W8ZZP1</accession>
    <name>A0A9W8ZZP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cys/Met metabolism PLP-dependent enzyme-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8J55DRAFT_459866</name>
        <name evidence="8" type="ORF">C8R41DRAFT_907338</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Min B."/>
                <person name="Riley R."/>
                <person name="Sierra-Patev S."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Hibbett D.S."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="journal article" date="2023" name="Proc. Natl. Acad. Sci. U.S.A." volume="120" first="0" last="0">
            <title>A global phylogenomic analysis of the shiitake genus Lentinula.</title>
            <authorList>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Donoghue J."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="LaButti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D."/>
            </authorList>
            <dbReference type="PubMed" id="36848567"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">Sp2 HRB7682 ss15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFS010000032">
        <property type="protein sequence ID" value="KAJ4470337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000003">
        <property type="protein sequence ID" value="KAJ4501024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9W8ZZP1"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150238">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4470337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4501024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001150238"/>
        </source>
    </evidence>
    <sequence length="436" mass="46572" checksum="F38B332778A7F61A" modified="2023-11-08" version="1">MADSQQFHKAPEFDTLMVHAGQTPDTAVHSRAVPIYATTSFVFNDSAHGADLFGLKTPGFIYSRIGNPTVDVFENRMAALEGGVGAVATASGQAAQFLAISALADVGDNVVTSSFLYGGTYNQFKVTLKKYGIHAKFVTETDPAAFAAAIDEKTKAIYIESITNPKYHVIDIPVLAEIAHKHGIPLVVDNTFGMGGYLIRPLDHGADIVVHSATKWIGGHGTTIGGVIIDGGKFNWKSPKFPGFTNPAEGYHGLVFADLGPAAFSIKVRTEFLRDVGPCLSPFAAFLLLQGLETLSLRGERHSSNALAVAQYLEKHPNVKWVSYLGLTSHKSHETAKKLLRPGVFGGILSFGLDGDAATGSKFVDSLKLASNLANVGDAKTLVIHPASTTHSQLTEVEQLQSGVPPDLIRVSIGIEDYRDIIADLDAGFKIAFEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UW84</accession>
    <name>A0ABQ8UW84_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C8R41DRAFT_783506</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JANVFT010000155">
        <property type="protein sequence ID" value="KAJ4463689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="173"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ4463689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="479" mass="52432" checksum="20B51F869F73F70A" modified="2025-10-08" version="1">MTSNAGTFDTASPTSSPTVSEYDWNTSAPSTRTNSRAPSMSSGVAGSKLQMSKPSAVMTPAASAANGVQRSVSTNSAISNTHATLEPASPAVGSRPKPSSIHSTDGEKHRFTLKDLLANGPKLARKSSQRSTGSRSSRKSDGGESDGGGYKSGGAAKSTAGDSTTSLSKKYGVCQKVAIGKGATSVVRLAHKWDRSEERLYAVKEFRKRRKNETEKEYVKKLTAEFCISSTLHHTNIVETVDLVQDESQHWCEVMEFCPGGDLYAAIKKGGMSPSEVECCFKQILCGVEYLHSQGVAHRDIKPENLFFDTKGHLKIGDYGASTVYRLPWEATIHMSTGLCGSEPYIAPEQFLGKPYDARLVDIWACGVVYYCLHFSELPWRAAQQSDQLFASYAEACKSPQPSQSACPPTINNLSPRACRTLLRRMLEPDPKLRAPIEEVMKHQWIHSIEVCHEVPEPKHVHVHARQLARAQLKELRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UWV3</accession>
    <name>A0ABQ8UWV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_131626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000145">
        <property type="protein sequence ID" value="KAJ4464181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="19304" checksum="E006A8E0CC065288" modified="2025-10-08" version="1">MMVRWHLWFVAFETCLIFSFIEIPLRFKPRNSYLNTTARHYLFTLHIIPYNIRFLWRFTRLQFPCARRQNYITLHDLSLCPRVSDRVSVSLFQSLRLQTPSTLFTATPPPPCPLLLRLDFGGVMNDSLVGLRNSMCVFSRPWSSYQFSLWATTFTVDFDCFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXC8</accession>
    <name>A0ABQ8UXC8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_859346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000135">
        <property type="protein sequence ID" value="KAJ4464710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="394" mass="43985" checksum="AD8A465B83387627" modified="2025-10-08" version="1">MCASNSKLFQPIRVGRMSLDHRIIYAPQTRYKATRNGHVPMLPIVKEYYSQRASMPGTLIITEAVLVSDKAGGKTHLPGIWSQDQIDAWRMVASEIHAGGCFAFMQIWALGRAAEYEDPGVEDTSKPFEYVSSSDVQLFGLKDKPPRPLTLSEIKEYISDFGKAASNAVHGAGFDGVEVHAANGYLCDQFTQDVANKRTDEYGGSIEGRCKFVIDVMNEVAKAVGEDRVAVRLSPWSLFQNMRMADPIPTFSYLVTKLKESLPGIAYLHVVEPRINGSKTERAENIVQTDSNDFLRQIWHPKPLISAGGYTRETAMQIANEKEDLIAFGRYFISNPDLPSRIIHNHPLAPYDRDTFYTRGDDSGRGYTDYAFYTPDAQGGLTTKEAFAKLVYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXF4</accession>
    <name>A0ABQ8UXF4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_859295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000134">
        <property type="protein sequence ID" value="KAJ4464817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5047402347" evidence="1">
        <location>
            <begin position="19"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4464817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="213" mass="22786" checksum="2B8A58EF7EED3DF2" modified="2025-10-08" version="1" fragment="single">MGGCVLLPLFFLMSLTIGGQTCVATKDCSIYYSVLSRSFVRHFLGNSPNDNISALVNIRHSNFAFTSRVDFVVLDELVGCEATFGLQFRQTCSFLQCLGLFELLPDTKTLLEHCVPSPRLLSVIGLPGSSAMLPDGVGPLFPLLSNPKTTRNMAVLSTHDGEGFFAAPNNGNNNCLPSTSSTADLPSMSIPSAQLLNLCLFGNSKSGILSLCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UXG2</accession>
    <name>A0ABQ8UXG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dipeptidyl peptidase 3</fullName>
            <ecNumber evidence="11">3.4.14.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl aminopeptidase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl peptidase III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_926797</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.</text>
            <dbReference type="EC" id="3.4.14.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.4" evidence="11"/>
    <dbReference type="EMBL" id="JANVFT010000134">
        <property type="protein sequence ID" value="KAJ4464816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005317">
        <property type="entry name" value="Dipeptidyl-peptase3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF11">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007828">
        <property type="entry name" value="Dipeptidyl-peptidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR007828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4464816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="726" mass="81104" checksum="065BEBB6E8F3AA45" modified="2025-10-08" version="1">MFILRGLRPRAIYNGLHYPLSSSQKPNLRKNFMASANAHSERFLADRAAPLCSLDISKTFAQLSSQEKKYTHHISEAAWAGARIIQAQWTPQANDLYDLLILTFTDDGKLADLKKLQSASRLTAEEWEDIMQYTVQVLSNLVNYRSFGFTKIIPRISDIKFEAVVQQCANSNKALEMWYKLKEHIYATEPSTSLFIGKRSEGHVSNYYLGEVISDEEVGDVQTAAENLGVDVLNTRLRKNGQEDFTLLVASAQSKPSAVHYISAKSGSFKLTVEYGDHAAALKKVVVSLKEAKKYTANSHQANMVEKYIDSYNTGSIQDHKDGSTEWVKDTGPIIESYLGFIETYVDPYGGRAEWEGFTAVVNKALSAKYDTLVAQAPKLIEVLPWGKDFEVETFRKPDFTALEVVSFATGGIPAGINIPNYYDIRETVGFKNVSLANILAAKAPNEELTFIHPDDAKLYNEWDQRAFELQVANHELLGHGSGKLLKENGDGSKNFDPSVINPLTGDPVTSWYKPGQTPDAVLGEVSSSVEECRAETVALFLVGNRDILKIFNYVDEQEIEDIQYITFLLMARAGLRALEFFDPATQKHGQAHMQARLGITQFLMRNGIARLEEVRDSDDKLENVFVRVDRDQVLARGKDVAGKLLVSLQVYKSTADGAGARKFYTELTTPMSGWDGELRDLVLKKKLPRKIFVQPTTAIVDGEVQLKEYPLTSAGAIESFIDRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UYT9</accession>
    <name>A0ABQ8UYT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Avidin/streptavidin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_926203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the avidin/streptavidin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000117">
        <property type="protein sequence ID" value="KAJ4466215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.30">
        <property type="entry name" value="Avidin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005469">
        <property type="entry name" value="Avidin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036896">
        <property type="entry name" value="Avidin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005468">
        <property type="entry name" value="Avidin/str"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051764">
        <property type="entry name" value="Avidin/Streptavidin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34399">
        <property type="entry name" value="AVIDIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01382">
        <property type="entry name" value="Avidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00709">
        <property type="entry name" value="AVIDIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50876">
        <property type="entry name" value="Avidin/streptavidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51326">
        <property type="entry name" value="AVIDIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5045437238" evidence="6">
        <location>
            <begin position="19"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4466215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="168" mass="17750" checksum="FE07CFFB924D745B" modified="2025-10-08" version="1">MTRYLVTLLVLGLSCVSGAPTASESPQVGNQLSMNLETIAPTATLGYIAGELSGTWINKLGSTVTLIADQAGGLSGQYYSAVGAASGFYNLTGRFDSLPPAGRGVSVGWVVTWNNKGRNAHSTTTWSGQYFNKGGSKTLITQWLLTASTTPNNVWASTTIGHDEFIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZF7</accession>
    <name>A0ABQ8UZF7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_871498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000111">
        <property type="protein sequence ID" value="KAJ4466959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4466959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="475" mass="51902" checksum="01C895D2DC2F7723" modified="2025-10-08" version="1">MTARLNESGNIELSHGKYGPHVKAMATLSPEDLDDLYEDSHQFAKLHSEETIDNICEVIADAFSARVHRDWFRSEKATHLALALEQKDPVDDTGPPTFPFLDALRRKFCRHDWAQVHSARRDDLRMSVGGVGCFDEYLSQVEGCNNCLKGVGNYLTPPQLLTILARGIATTLTAILSEQGTVIDETTVYKDWITSCRDLEVRFKTCLMSADRTGRRGNFPSGGSNNLPPHKRTATSDPSGHPNKRLTTDGPPSNTGMGPFYMRAFSKMPEAMQKEQRELLSCISACVKCHTAWGTCASNLDKCPGAMLSVPWRPLTKEMVDWAIAAHKSTGRPILYNAILKQANSAISVSSVQGPPLEDISAYITNNTTRAPPAAAIYGARSVAHVARGENVYGSFAGPSMRHSDFSSSSRASQIVAPVIGQCRLTRNDADEDVDWSDRSMSPSPASRTKAIAMIKKEPLSGSENDEGVVSDNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZI8</accession>
    <name>A0ABQ8UZI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_925873</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000110">
        <property type="protein sequence ID" value="KAJ4467094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4467094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="464" mass="50445" checksum="AE68CBE5C745EFF9" modified="2025-10-08" version="1">MVSAENTMVVPLSGIDQNGVHTSSITFGYVVARLDVEALEAAAIRAAEEWRLLAGRVEWNATIKSFQVRVPVSGSLPKDYALVKFTTSKLPSTKLPITPFDDSSATFLERPPVKLFRHSSTLNSLSDYASKKAPILSLHVSLMANCACVGMTLPHGIFDATGMGQVVQALNSCLNNLPWTPPKISSSSILAEELKRLRESESVGDPCPPGLVNLQRDFTSVNVKNVLTLGASCATELLWHRVKPAAIYLGSNVVQEMVANVKKQAADEGKGWVSTGDILVAFLLKAAYLDEGPTSPNALTMSAAVSLRSVLAATNRDFESYTHNALLPLALPPLTVQQVSSMSLYEFALIHRKAIEDMRNIPYIQGYEKWVPSIGGAAIPARRKGTDSWLLSNQVVGGVDKLDLGSEPLGFWHWMLPFMPDHVFTVNKLRGGYILDGFSGVRPQRLKAIEKALEGIRRGEPLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8UZU0</accession>
    <name>A0ABQ8UZU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C8R41DRAFT_855671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000108">
        <property type="protein sequence ID" value="KAJ4467346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="653"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="725"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="664"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ4467346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="950" mass="105159" checksum="087C7E9F18FF5DBF" modified="2025-10-08" version="1">MGASVKEKQTDAKKTTAKRRPGRTATSCAECRRLKLRCDRQVPCGKCVSRGCAAICPDGSLTAGKGNRLVLANTEQLHDRIEQLCSRIRELESALRGAQAQLSEEEHPLLRSELLQLKSPHTVYPKNKPDHQTADPLIASGTHPSPTQNYSSSTKNPEDENLIDAFGTLSIRENGETQFLGQTARSEYLIRALAKPQKSSIPISCTRLSQKIINGAHFCRDDSEPSYGNSVTSERDIYELGQEVFGLLPPLSEAIRLCEVYLEYGKYMYTPLPRTQLFDEILASIYRSDSFDTIRCYHSLSLIFIIFAIASLFDPSLPSCSVQAQEYFYLSKAALSFNSPFSHTTFKSIWCMLHIAQFLEFSDWEAMGSTAGWAYIGHVVRMGTSIGFHLNSSRWSLPHEIQQMQYRLFWTVFTADTWSSFYYGRPPSLSRAYVDCPLPKDTEEFVSADGEREPGFHYWSWQFTAFVHTIMEETFGSSRPAYSTIIDFDRKIRDFLIPVNLRVKCGALETRQDLYLQRLIVMCYKENMLMHLHRAYFAQALQDSPDDLTTHKYVASVIATYRSAWRLSKAMQIAWMHIPHLLARYHLAWSQVLSSAIVMCILVTRAPNSKMTKSSVEELDGMTSLFEEAAPTSRSAANILDTMRNLRRKAREVIDTAASPDRTSNSGSPAESSSSQAGSDHSPSARSPPCAVSFTSTADLKEAQGIPLSTFELDRLGGRTHLISACKSSKPSTPVEKPASPPNSSDTGSDAHPSPEILASLPPSMSWAHGESQQHLQQLAPVQNLHPTIVQDIRNIEMDVDMNFGGFELHFLDTPTANRTETEQSFGLSLGQQQGGQDTSQLGNASLRYPTALAGSQNQDIVTSSSSSHYSGMSGMAFDFMSMGGEDTSLHMGDLSTMGGGNAFGNSMVSPSFSTGTFSTLGYPPANTQLLPGTPVLDASWQSFVEQLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0B5</accession>
    <name>A0ABQ8V0B5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C8R41DRAFT_869971</name>
        <name evidence="2" type="ORF">C8R41DRAFT_872279</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000149">
        <property type="protein sequence ID" value="KAJ4463954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JANVFT010000075">
        <property type="protein sequence ID" value="KAJ4475126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4463954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ4475126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="191" mass="20936" checksum="210E57F87349A577" modified="2025-10-08" version="1">MSFGSDPESFLEYALSLPDPVSPDPETSDPSDQSSPSDHNSEQESVQSGTNSDPDQSSYDSEFPGPFDYDYLYQSSDFDSDHPGPYDLSYLHSYPSSSASDSHESFHSFASEASEAPELRPGDDRSGHPHLGPDGRLVDSERERRRVLGLCFYCGGEHMKVDCLKLQARTGENYDADDSESDIPGSDDGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0D2</accession>
    <name>A0ABQ8V0D2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_984757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000104">
        <property type="protein sequence ID" value="KAJ4467855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4467855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="314" mass="34517" checksum="02793981B440B07F" modified="2025-10-08" version="1">MSVRQLKEEKTRRRRPTASGTTRPYVPQAASTINRPVINRLANFPAEPHIPVPPKGRAQTPYHPTIPPPDDDEEDEPPPPVVVPSVAGSVHLPSVLEHRQRHSEPLYHQIIPPPPPVDSTRQSAFDRPLWSPSGNPLPEPPRDPFNSEAYNSLDKDVARDRVRLGDVRLVPSSVLVERVNGETSSTAEVNEIAMDGVIPPPPVLKEQTGGSPPFLVMLGPSAAPAVGPSQINVPFPVITIPRAPSADQQPLFPPESPERHVYLHPILANLSRFLSPYPHRVLHNNFYPTATYLHEALKYLSAQPSPPKSAYALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0G1</accession>
    <name>A0ABQ8V0G1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pheromone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C8R41DRAFT_858606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000128">
        <property type="protein sequence ID" value="KAJ4465328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012597">
        <property type="entry name" value="Pheromone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08015">
        <property type="entry name" value="Pheromone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ4465328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="60" mass="6320" checksum="0E8A40A5A4A7EF99" modified="2025-10-08" version="1">MDNFNTLNTMFPTTTFIADSPDDRSLTLLSDNTHCAPAPSVPVDSEAVGSGDIIGFCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0R1</accession>
    <name>A0ABQ8V0R1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C8R41DRAFT_778737</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CHS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ4468491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="360" mass="39443" checksum="AA16A877F3C2070F" modified="2025-10-08" version="1">MGIKFGSFDSVCETAALVICPLVGTDQGVEPTCYSRNVDVGGTLIFQPSTCFVHIAAIIMTIIMILHIRSKYTAVGRKEIIMLFYMYLVISLLAMFLDSGIIPTANAAYPWFAAIYTGLIASAYCCLLINAFVGFQFAEDGTPLSLWLLRICCFVVWGIGFFVGIATFKQFASFSYSNPIALWIVYLIWPIVCVAVYIVSQLILVFRTLEDRWPIGDIVFGAAFWVIGMVLLFAFSDTICNAIEHYLDGLFFQELCVLLAIMMVYKYWDSITREDLEFSVGSKAAVWEVKDPLLSGSAGYPSRGDYSEEDVGSNYGGYAPPPGFGNNKTASLVGGVSGAQLYDRKGYGAGGRGYPPAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V0U5</accession>
    <name>A0ABQ8V0U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_854423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000101">
        <property type="protein sequence ID" value="KAJ4468522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4468522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="277" mass="30742" checksum="07908BF5BD01FC16" modified="2025-10-08" version="1">MASTFSISSSVKLSTGYLMPVLGFGVYQNYDARTSCLEAFKAGYRHVDSAQMYRNEAAVGEAVRESGINRSALFITTKCASRSHGYESTLSGVDESLSKLQFDYVDLFLIHDPLSGSEKRLATYKALQECKTAGKIRTVGVSNYNVKHLEEIRNAGYDLPAVNQIELHPFCQQKPIVEYCLKNSIVVQAYCPIIRGKTDHEVFNSIAVKHNHDPAQVLIRWSLQKGFVPLPKSATPSRIHSNAQVFDFELDADDMARIDALDQGKQGAISWNPVDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V229</accession>
    <name>A0ABQ8V229_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AN1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_854441</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000102">
        <property type="protein sequence ID" value="KAJ4468052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057357">
        <property type="entry name" value="Znf-C2H2_ZFAND2A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF40">
        <property type="entry name" value="CDC48-ASSOCIATED UBIQUITIN-LIKE_ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25403">
        <property type="entry name" value="zf-C2H2_ZFAND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="7">
        <location>
            <begin position="110"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4468052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="272" mass="29633" checksum="65DF493705B3377C" modified="2025-10-08" version="1">MPSSSARATPKPEQDGPLLAIGKQCSHSTCQLVDFLSFKCQHCHGSFCQDHYKVAEHSCPDYDESKHNRIAPNCPLCNEPVAIRPGTDPNVRMEAHFATECSVMTGHVAKKSTPICAQRKCGKVLFAPIHCDKCRKSFCPSHRFPGDHACNTTHPARSSAPANALPFTLNVKAASHAASSTVGAIKKTMSSTTNASVAAPSQVPVTTSKSAPPMPNPFSKVDRRAKLERESMRRALQERAKKGLLTEEEKLRLASQEAEEAQERKRGDCVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V270</accession>
    <name>A0ABQ8V270_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C8R41DRAFT_852182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000092">
        <property type="protein sequence ID" value="KAJ4470314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ4470314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="381" mass="43087" checksum="BB5F7696C3499557" modified="2025-10-08" version="1">MGTFLTLPVELIADVLSELDLDSLIIISYLSRRLHDIVSDPSLNPWRKPILRSLRSSQIEGSSGSLKHLSVRRIVPRHNWIEILSLASPSFILLDATLPNLRSEEWEECFNRRFLPGWRKWHKEGSWKATYLEVLHRVYHRSRTSCTSDESWTKYIVLNRNGTANELEGSSRGFNPLAIFNEMKLQNNLMHLETRIRLVVELTDVRIIALGTLDRPRSTLTVNPNAHTFLHPPGIDDLQAPRNNRVVTDHGVYPLGPNLADYPGVSPPSIDFSHMTHPLPVSSHANYPWYTPGGGDKRWLGSGEVEEEGLKWVGGLMIITQILMPKTHELGGDWLPLQDLDLVVGSGRQQYASLGWSDLWAIAPWMEERISNKIDGPGLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3N4</accession>
    <name>A0ABQ8V3N4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_888686</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000083">
        <property type="protein sequence ID" value="KAJ4472685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12400">
        <property type="entry name" value="RRM_Nop6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034228">
        <property type="entry name" value="Nop6_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF51">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="134"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ4472685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="310" mass="34283" checksum="57BEE15710722AC4" modified="2025-10-08" version="1">MNSSKLTKKQKKGIAFRSGKLGKGARKNDVGTSSNDTEYNSVPVLEIQDGLDIEDVEMENETVFSEEKIKDATVSAREKGKGKAIEEKADAVTVPPNKRKRGSEPVMEKVKDGEGKEENVPKKKKKGNDEKQRFILFVGNLKYTTPIDSVKEHFSVCDPPPFVRLLTPKTSTPNNKSKGCAFLEFTHRNALQQALKLHQSRLDGRAINVELTSGGGGKSEARLQKLKERNKKLHDQRTERQGMNEENSTQPERYSATSGIGATPGAKKTWTVDDVGHGTVHRGGKKHNKKRDRSQHSNEWGTGVNAIPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V3W0</accession>
    <name>A0ABQ8V3W0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C8R41DRAFT_854676</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JANVFT010000103">
        <property type="protein sequence ID" value="KAJ4468018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ4468018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="314" mass="35581" checksum="69ECF414606649C3" modified="2025-10-08" version="1">MAPFDLDACIEQLLRKQLLHEALLREICEKTKEVLMRESNVVHVSAPVTVVGDIHGQFYDLIEIFRIGGYAPNTNYLFLGDYVDRGLFSVETISLLTCLKLRYPDRVQLIRGNHESRAVTQTYGFYTECVRKYGSSHVWTYFTDMFDFLTLSVVIDDRIFCVHGGLSPSIHSIDQIKVVDRFREIPHEGPMADLVWSDPDPEKEDFAISPRGAGYTFGSGVVHKFLEINRMSHILRAHQLCMEGYASLFDRHLSTVWSAPNYCYRCGNSASILEVGPGGSMYFNVFEAAPENERDGPTQQAAQNASGKLPEYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V409</accession>
    <name>A0ABQ8V409_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C8R41DRAFT_779469</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000106">
        <property type="protein sequence ID" value="KAJ4467598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ4467598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001150217"/>
        </source>
    </evidence>
    <sequence length="517" mass="58619" checksum="5346D2CFE59FE7F6" modified="2025-10-08" version="1">MIDFGPSLNTPMLGEIISSFSLKVFVIVSLAYITYRELSFRRKRLPPGPTPLLMIGNVLQIPSISPQKKFAEWLDVYGDVVYLRIFQQPMLILNSLEAAQDLLHQRSSIYSDRPNFVLLNDLMGWQNASTHVRYGPRFRRHRRFIHQTFNQRAVETLRSVQEKEISHLIQDLIREPEQVAQHLQRFTAATIMKITYGADVKSNDDPFVQLAQRAGSLTIQSGTPAATLVDYIPIMRYIPSWAPLAGFKRNAGIVKEAVDSMFNIPYETVKGQMASGIDFPCMTSRLMKACSPAGVHYLSLEDEEDIKGVAGTMYAAAEDTTHCILSTFILAMVLHPEVFKKAQAEMDDVVGMDRLPTFEDRSSLPYLECVLKEVCRWNVPVPLGLPHRLMNVDVYRNYHIPKGTTVMANIHSILQNCSQPQLFRPERYIEDPNLLDPADVIYGFGRRRCPGRHFGDRTVWLAAASLVCTMIISKTKDEHGNDITPNATFVNGFVRHPSEFPCNIQPRSERILMMTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2025-10-08" modified="2026-01-28" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0ABQ8V4Q2</accession>
    <name>A0ABQ8V4Q2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C8R41DRAFT_848145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lentinula lateritia</name>
        <dbReference type="NCBI Taxonomy" id="40482"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Marasmiineae</taxon>
            <taxon>Omphalotaceae</taxon>
            <taxon>Lentinula</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2022-08" db="EMBL/GenBank/DDBJ databases">
            <title>A Global Phylogenomic Analysis of the Shiitake Genus Lentinula.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Sierra-Patev S."/>
                <person name="Min B."/>
                <person name="Naranjo-Ortiz M."/>
                <person name="Looney B."/>
                <person name="Konkel Z."/>
                <person name="Slot J.C."/>
                <person name="Sakamoto Y."/>
                <person name="Steenwyk J.L."/>
                <person name="Rokas A."/>
                <person name="Carro J."/>
                <person name="Camarero S."/>
                <person name="Ferreira P."/>
                <person name="Molpeceres G."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Serrano A."/>
                <person name="Henrissat B."/>
                <person name="Drula E."/>
                <person name="Hughes K.W."/>
                <person name="Mata J.L."/>
                <person name="Ishikawa N.K."/>
                <person name="Vargas-Isla R."/>
                <person name="Ushijima S."/>
                <person name="Smith C.A."/>
                <person name="Ahrendt S."/>
                <person name="Andreopoulos W."/>
                <person name="He G."/>
                <person name="Labutti K."/>
                <person name="Lipzen A."/>
                <person name="Ng V."/>
                <person name="Riley R."/>
                <person name="Sandor L."/>
                <person name="Barry K."/>
                <person name="Martinez A.T."/>
                <person name="Xiao Y."/>
                <person name="Gibbons J.G."/>
                <person name="Terashima K."/>
                <person name="Grigoriev I.V."/>
                <person name="Hibbett D.S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RHP3577 ss4</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JANVFT010000078">
        <property type="protein sequence ID" value="KAJ4474174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001150217">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference p
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